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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
PFPHHAOO_00011	1.83e-21	-	-	-	-	-	-	-	-
PFPHHAOO_00013	1.59e-217	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
PFPHHAOO_00014	9.5e-238	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
PFPHHAOO_00015	1.39e-208	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
PFPHHAOO_00016	3.66e-314	steT	-	-	E	ko:K03294	-	ko00000	amino acid
PFPHHAOO_00017	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
PFPHHAOO_00018	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
PFPHHAOO_00019	1.03e-19	-	-	-	-	-	-	-	-
PFPHHAOO_00020	1.45e-149	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
PFPHHAOO_00021	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
PFPHHAOO_00022	9.93e-115	ykhA	3.1.2.20	-	I	ko:K01073	-	ko00000,ko01000	Thioesterase superfamily
PFPHHAOO_00023	2e-206	-	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	PFAM extracellular solute-binding protein, family 3
PFPHHAOO_00024	1.06e-258	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
PFPHHAOO_00025	3.94e-221	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
PFPHHAOO_00026	2.76e-215	lutA	-	-	C	ko:K18928	-	ko00000	Cysteine-rich domain
PFPHHAOO_00027	0.0	lutB	-	-	C	ko:K18929	-	ko00000	4Fe-4S dicluster domain
PFPHHAOO_00028	1.5e-176	lutC	-	-	S	ko:K00782	-	ko00000	LUD domain
PFPHHAOO_00029	1.08e-215	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
PFPHHAOO_00030	9.42e-234	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
PFPHHAOO_00031	9.5e-200	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PFPHHAOO_00032	3.96e-226	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
PFPHHAOO_00033	1.88e-68	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
PFPHHAOO_00034	4.27e-66	-	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain protein
PFPHHAOO_00035	1.58e-238	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PFPHHAOO_00036	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
PFPHHAOO_00039	1.52e-08	-	-	-	D	-	-	-	nuclear chromosome segregation
PFPHHAOO_00040	1.22e-60	-	-	-	D	-	-	-	nuclear chromosome segregation
PFPHHAOO_00042	8.49e-08	-	-	-	K	-	-	-	peptidyl-tyrosine sulfation
PFPHHAOO_00048	2.44e-266	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
PFPHHAOO_00049	1.76e-313	-	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	pyridine nucleotide-disulfide oxidoreductase
PFPHHAOO_00050	3.38e-109	yvbK	-	-	K	-	-	-	GNAT family
PFPHHAOO_00051	4.18e-119	-	-	-	-	-	-	-	-
PFPHHAOO_00052	5.93e-156	pnb	-	-	C	-	-	-	nitroreductase
PFPHHAOO_00053	2.07e-97	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Methyltransferase
PFPHHAOO_00054	2.36e-216	-	3.2.1.96, 3.5.1.28	GH73	M	ko:K01227,ko:K01447,ko:K13714,ko:K13731	ko00511,ko05100,map00511,map05100	ko00000,ko00001,ko01000	N-acetylmuramoyl-L-alanine amidase
PFPHHAOO_00055	2.62e-89	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
PFPHHAOO_00056	1.43e-100	-	-	-	K	-	-	-	LytTr DNA-binding domain
PFPHHAOO_00057	1.46e-119	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
PFPHHAOO_00058	3.39e-92	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
PFPHHAOO_00059	4.75e-240	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
PFPHHAOO_00060	3.83e-70	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
PFPHHAOO_00062	8.48e-28	-	-	-	T	ko:K06919	-	ko00000	Phage plasmid primase, P4 family
PFPHHAOO_00067	2.05e-112	-	-	-	K	-	-	-	Transcriptional regulator
PFPHHAOO_00068	9.36e-178	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
PFPHHAOO_00069	3.71e-142	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
PFPHHAOO_00070	9.77e-185	-	-	-	C	-	-	-	Aldo keto reductase
PFPHHAOO_00071	2.3e-151	-	-	-	GM	-	-	-	NmrA-like family
PFPHHAOO_00072	1.33e-155	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
PFPHHAOO_00073	1.58e-90	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
PFPHHAOO_00075	2.62e-31	-	-	-	EGP	ko:K08166	-	ko00000,ko02000	Major Facilitator Superfamily
PFPHHAOO_00076	3.18e-133	-	1.1.1.65	-	C	ko:K05275	ko00750,ko01100,ko01120,map00750,map01100,map01120	ko00000,ko00001,ko01000	Aldo/keto reductase family
PFPHHAOO_00077	1.24e-80	yphH	-	-	S	-	-	-	Cupin domain
PFPHHAOO_00078	3.2e-61	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	decarboxylase
PFPHHAOO_00079	6.49e-228	-	-	-	L	-	-	-	Transposase DDE domain
PFPHHAOO_00080	3.39e-92	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
PFPHHAOO_00081	4.75e-240	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
PFPHHAOO_00082	3.83e-70	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
PFPHHAOO_00084	3.39e-86	-	-	-	M	-	-	-	Rib/alpha-like repeat
PFPHHAOO_00086	3.83e-70	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
PFPHHAOO_00087	4.75e-240	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
PFPHHAOO_00088	3.39e-92	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
PFPHHAOO_00089	3.68e-155	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
PFPHHAOO_00090	1.31e-189	epsB	-	-	M	-	-	-	biosynthesis protein
PFPHHAOO_00091	2.21e-213	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
PFPHHAOO_00092	6.74e-53	-	-	-	K	-	-	-	Transcriptional regulator, HxlR family
PFPHHAOO_00094	3.83e-70	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
PFPHHAOO_00095	4.75e-240	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
PFPHHAOO_00096	3.39e-92	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
PFPHHAOO_00097	0.0	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
PFPHHAOO_00098	6.28e-19	-	-	-	-	-	-	-	-
PFPHHAOO_00099	5.32e-206	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
PFPHHAOO_00100	8.66e-70	-	-	-	S	-	-	-	Mazg nucleotide pyrophosphohydrolase
PFPHHAOO_00101	1.05e-45	-	-	-	-	-	-	-	-
PFPHHAOO_00102	3.03e-83	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
PFPHHAOO_00103	0.0	-	-	-	E	ko:K03294	-	ko00000	amino acid
PFPHHAOO_00104	5.46e-183	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
PFPHHAOO_00105	1.47e-116	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PFPHHAOO_00106	3.74e-53	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
PFPHHAOO_00107	1.21e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
PFPHHAOO_00108	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PFPHHAOO_00109	4.23e-76	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
PFPHHAOO_00110	3.67e-260	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
PFPHHAOO_00111	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
PFPHHAOO_00112	1.57e-168	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
PFPHHAOO_00113	1.81e-50	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PFPHHAOO_00114	5.51e-240	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
PFPHHAOO_00115	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PFPHHAOO_00116	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
PFPHHAOO_00117	1.05e-77	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
PFPHHAOO_00118	1.1e-34	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
PFPHHAOO_00119	4.7e-157	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
PFPHHAOO_00120	4.49e-151	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
PFPHHAOO_00121	2.33e-206	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
PFPHHAOO_00122	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
PFPHHAOO_00123	1.17e-165	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
PFPHHAOO_00124	2.81e-314	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PFPHHAOO_00125	1.43e-222	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PFPHHAOO_00126	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PFPHHAOO_00127	5.06e-263	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PFPHHAOO_00128	6.66e-43	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
PFPHHAOO_00129	3.59e-147	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
PFPHHAOO_00130	8.66e-70	-	-	-	-	-	-	-	-
PFPHHAOO_00131	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
PFPHHAOO_00132	1.85e-99	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
PFPHHAOO_00133	2.81e-191	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
PFPHHAOO_00134	1.24e-198	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
PFPHHAOO_00135	1.15e-57	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PFPHHAOO_00136	2.66e-278	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PFPHHAOO_00137	3.63e-189	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PFPHHAOO_00138	1.84e-91	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PFPHHAOO_00139	2.27e-93	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
PFPHHAOO_00140	1.73e-147	-	-	-	J	-	-	-	2'-5' RNA ligase superfamily
PFPHHAOO_00141	3.54e-255	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
PFPHHAOO_00142	2.13e-167	-	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
PFPHHAOO_00143	5.93e-60	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
PFPHHAOO_00144	8.44e-71	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
PFPHHAOO_00145	2.68e-67	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
PFPHHAOO_00146	3.16e-143	-	-	-	K	-	-	-	Transcriptional regulator
PFPHHAOO_00149	5.52e-112	-	-	-	S	-	-	-	Protein conserved in bacteria
PFPHHAOO_00150	1.67e-229	-	-	-	-	-	-	-	-
PFPHHAOO_00151	8.07e-202	-	-	-	-	-	-	-	-
PFPHHAOO_00152	1.08e-67	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
PFPHHAOO_00153	2.72e-129	msrA	1.8.4.11	-	C	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PFPHHAOO_00154	1.28e-18	-	-	-	-	-	-	-	-
PFPHHAOO_00155	6.49e-228	-	-	-	L	-	-	-	Transposase DDE domain
PFPHHAOO_00157	3.83e-70	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
PFPHHAOO_00158	4.75e-240	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
PFPHHAOO_00159	3.39e-92	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
PFPHHAOO_00164	4.42e-51	int2	-	-	L	-	-	-	Belongs to the 'phage' integrase family
PFPHHAOO_00165	1.04e-165	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
PFPHHAOO_00166	5.63e-178	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PFPHHAOO_00167	2.43e-205	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
PFPHHAOO_00168	1.33e-47	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
PFPHHAOO_00169	1.16e-140	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
PFPHHAOO_00170	8.88e-217	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
PFPHHAOO_00171	6.12e-194	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
PFPHHAOO_00172	1.23e-142	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
PFPHHAOO_00173	2.78e-118	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PFPHHAOO_00174	1.41e-244	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PFPHHAOO_00175	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
PFPHHAOO_00176	7.84e-284	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
PFPHHAOO_00177	1.24e-296	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
PFPHHAOO_00178	1.6e-54	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
PFPHHAOO_00179	6.66e-316	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
PFPHHAOO_00180	1.49e-274	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
PFPHHAOO_00181	2.64e-148	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
PFPHHAOO_00182	1.04e-69	-	-	-	M	-	-	-	Lysin motif
PFPHHAOO_00183	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
PFPHHAOO_00184	1.43e-250	-	-	-	S	-	-	-	Helix-turn-helix domain
PFPHHAOO_00185	2.09e-130	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
PFPHHAOO_00188	8.97e-16	-	-	-	-	-	-	-	-
PFPHHAOO_00190	2.89e-168	lysA2	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
PFPHHAOO_00191	2.63e-46	-	-	-	S	-	-	-	Bacteriophage holin of superfamily 6 (Holin_LLH)
PFPHHAOO_00192	8.4e-53	-	-	-	-	-	-	-	-
PFPHHAOO_00194	3.15e-76	-	-	-	S	-	-	-	Domain of unknown function (DUF2479)
PFPHHAOO_00195	5.31e-86	dex	3.2.1.11	GH66	G	ko:K05988	ko00500,map00500	ko00000,ko00001,ko01000	Cycloisomaltooligosaccharide glucanotransferase
PFPHHAOO_00197	1.96e-38	-	-	-	-	-	-	-	-
PFPHHAOO_00198	0.0	-	-	-	M	-	-	-	Prophage endopeptidase tail
PFPHHAOO_00199	2.08e-199	-	-	-	S	-	-	-	Phage tail protein
PFPHHAOO_00200	0.0	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
PFPHHAOO_00201	6.2e-89	-	-	-	-	-	-	-	-
PFPHHAOO_00202	1.24e-170	-	-	-	S	-	-	-	Phage tail tube protein
PFPHHAOO_00203	1.39e-92	-	-	-	-	-	-	-	-
PFPHHAOO_00204	1.09e-114	-	-	-	-	-	-	-	-
PFPHHAOO_00205	2.05e-83	-	-	-	S	-	-	-	Phage head-tail joining protein
PFPHHAOO_00206	1.74e-92	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
PFPHHAOO_00208	4.1e-272	-	-	-	S	-	-	-	Phage capsid family
PFPHHAOO_00209	5.4e-177	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
PFPHHAOO_00210	1.15e-315	-	-	-	S	-	-	-	portal protein
PFPHHAOO_00211	0.0	-	-	-	L	-	-	-	Terminase
PFPHHAOO_00212	3.3e-114	-	-	-	L	-	-	-	Terminase
PFPHHAOO_00213	7.81e-102	-	-	-	L	-	-	-	Phage terminase, small subunit
PFPHHAOO_00214	5.01e-69	-	-	-	L	-	-	-	HNH nucleases
PFPHHAOO_00228	6.19e-12	-	-	-	V	-	-	-	HNH nucleases
PFPHHAOO_00230	4.75e-51	-	-	-	S	-	-	-	HicB_like antitoxin of bacterial toxin-antitoxin system
PFPHHAOO_00235	1.89e-152	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
PFPHHAOO_00236	2.51e-45	-	-	-	L	-	-	-	NUMOD4 motif
PFPHHAOO_00245	7.69e-263	XK27_11280	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
PFPHHAOO_00246	0.0	-	-	-	-	-	-	-	-
PFPHHAOO_00248	5.44e-99	-	-	-	S	-	-	-	Transcriptional regulator, RinA family
PFPHHAOO_00253	6.12e-166	-	-	-	F	-	-	-	deoxynucleoside kinase
PFPHHAOO_00259	2.36e-170	-	-	-	-	-	-	-	-
PFPHHAOO_00263	1.08e-88	-	-	-	Q	-	-	-	DNA (cytosine-5-)-methyltransferase activity
PFPHHAOO_00269	5.12e-101	rusA	-	-	L	-	-	-	Endodeoxyribonuclease RusA
PFPHHAOO_00270	1.31e-46	-	-	-	-	-	-	-	-
PFPHHAOO_00271	2.03e-26	-	-	-	-	-	-	-	-
PFPHHAOO_00275	8.91e-193	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
PFPHHAOO_00276	9.48e-172	-	-	-	S	-	-	-	Putative HNHc nuclease
PFPHHAOO_00277	5.07e-81	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
PFPHHAOO_00285	3.24e-149	-	-	-	S	-	-	-	Protein of unknown function (DUF3102)
PFPHHAOO_00286	2.11e-28	-	-	-	-	-	-	-	-
PFPHHAOO_00289	3.37e-63	-	-	-	K	ko:K07727	-	ko00000,ko03000	addiction module antidote protein HigA
PFPHHAOO_00290	2.64e-96	-	-	-	E	-	-	-	IrrE N-terminal-like domain
PFPHHAOO_00294	4.74e-86	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
PFPHHAOO_00295	1.49e-164	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
PFPHHAOO_00296	5.49e-135	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PFPHHAOO_00297	5.35e-175	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
PFPHHAOO_00298	1.23e-84	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PFPHHAOO_00299	1.93e-210	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
PFPHHAOO_00300	2.27e-216	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
PFPHHAOO_00301	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
PFPHHAOO_00302	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
PFPHHAOO_00303	3.79e-40	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
PFPHHAOO_00304	6.7e-303	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
PFPHHAOO_00305	2.94e-198	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PFPHHAOO_00306	8.96e-160	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
PFPHHAOO_00307	7.19e-280	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
PFPHHAOO_00308	1.03e-265	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
PFPHHAOO_00309	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
PFPHHAOO_00310	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
PFPHHAOO_00311	2.5e-233	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
PFPHHAOO_00312	2.5e-188	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
PFPHHAOO_00313	6.02e-216	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PFPHHAOO_00314	1.66e-77	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
PFPHHAOO_00315	4.45e-109	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PFPHHAOO_00316	1.06e-233	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
PFPHHAOO_00317	3.46e-217	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
PFPHHAOO_00318	4.44e-112	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
PFPHHAOO_00319	5.09e-302	-	-	-	L	-	-	-	Transposase
PFPHHAOO_00320	0.0	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Thioredoxin domain
PFPHHAOO_00321	3.25e-136	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Peroxiredoxin
PFPHHAOO_00322	3.37e-193	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
PFPHHAOO_00323	3.55e-154	sdhB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
PFPHHAOO_00326	1.39e-232	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
PFPHHAOO_00327	3.75e-45	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
PFPHHAOO_00328	6.69e-304	-	-	-	L	-	-	-	Integrase core domain
PFPHHAOO_00329	3.06e-126	epsB	-	-	M	-	-	-	biosynthesis protein
PFPHHAOO_00330	3.01e-140	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
PFPHHAOO_00331	8.24e-63	-	-	-	M	ko:K13012	-	ko00000,ko01005	Bacterial sugar transferase
PFPHHAOO_00332	2.44e-103	-	-	GT4	G	ko:K19422	-	ko00000,ko01000	Glycosyl transferase 4-like domain
PFPHHAOO_00333	2.59e-83	wefC	-	-	M	-	-	-	Stealth protein CR2, conserved region 2
PFPHHAOO_00334	2.34e-52	-	-	-	M	-	-	-	Glycosyltransferase GT-D fold
PFPHHAOO_00336	7.81e-85	cps2I	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
PFPHHAOO_00337	1.07e-49	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
PFPHHAOO_00338	5.7e-33	-	-	-	M	-	-	-	PFAM Glycosyl transferase family 2
PFPHHAOO_00339	2.97e-32	-	-	-	M	-	-	-	COG0463 Glycosyltransferases involved in cell wall biogenesis
PFPHHAOO_00340	1.77e-59	-	-	-	S	-	-	-	Glycosyltransferase like family 2
PFPHHAOO_00342	9.6e-35	-	-	-	S	-	-	-	Acyltransferase family
PFPHHAOO_00343	0.0	-	2.4.1.5	GH13	G	ko:K00689	ko00500,ko02020,map00500,map02020	ko00000,ko00001,ko01000	Glycosyl hydrolase family 70
PFPHHAOO_00344	6.69e-304	-	-	-	L	-	-	-	Integrase core domain
PFPHHAOO_00345	3.81e-41	-	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
PFPHHAOO_00346	9.14e-89	-	1.1.1.100, 1.1.1.304, 1.1.1.76	-	IQ	ko:K00059,ko:K18009	ko00061,ko00333,ko00650,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00650,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
PFPHHAOO_00347	5.37e-45	-	-	-	K	-	-	-	Bacterial transcriptional regulator
PFPHHAOO_00348	9.5e-162	pgm3	-	-	G	-	-	-	phosphoglycerate mutase family
PFPHHAOO_00349	1.7e-54	-	-	-	-	-	-	-	-
PFPHHAOO_00350	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
PFPHHAOO_00351	1.16e-263	gldA	1.1.1.6	-	C	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	dehydrogenase
PFPHHAOO_00352	3.84e-145	-	-	-	L	-	-	-	transposase IS116 IS110 IS902 family protein
PFPHHAOO_00353	9.63e-103	-	-	-	L	-	-	-	transposase IS116 IS110 IS902 family protein
PFPHHAOO_00354	1.6e-49	-	-	-	S	-	-	-	Alpha beta hydrolase
PFPHHAOO_00355	3.17e-106	-	-	-	S	-	-	-	Alpha beta hydrolase
PFPHHAOO_00356	7.69e-275	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
PFPHHAOO_00357	8.47e-126	-	-	-	-	-	-	-	-
PFPHHAOO_00359	8.11e-159	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
PFPHHAOO_00360	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
PFPHHAOO_00361	1.68e-139	nnrE	5.1.99.6	-	H	ko:K17759	-	ko00000,ko01000	Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
PFPHHAOO_00362	6.5e-111	-	-	-	-	-	-	-	-
PFPHHAOO_00363	7.97e-311	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
PFPHHAOO_00364	4.1e-272	yttB	-	-	EGP	-	-	-	Major Facilitator
PFPHHAOO_00365	1.91e-142	-	-	-	-	-	-	-	-
PFPHHAOO_00366	2.6e-33	-	-	-	-	-	-	-	-
PFPHHAOO_00367	5.37e-221	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
PFPHHAOO_00368	2.71e-51	-	-	-	S	-	-	-	Protein of unknown function (DUF1797)
PFPHHAOO_00369	9.33e-229	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PFPHHAOO_00370	2.29e-252	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
PFPHHAOO_00371	8.93e-291	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
PFPHHAOO_00372	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PFPHHAOO_00373	3.69e-54	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
PFPHHAOO_00374	5.62e-37	-	-	-	-	-	-	-	-
PFPHHAOO_00375	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
PFPHHAOO_00376	1.56e-130	-	-	-	S	-	-	-	Pfam:DUF3816
PFPHHAOO_00377	5.49e-182	-	-	-	G	-	-	-	MucBP domain
PFPHHAOO_00378	1.17e-147	-	-	-	-	-	-	-	-
PFPHHAOO_00379	2.92e-198	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PFPHHAOO_00380	1.19e-84	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
PFPHHAOO_00381	0.0	bamA	-	-	GM	ko:K07277,ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko02000,ko03016,ko03019,ko03029	domain, Protein
PFPHHAOO_00382	0.0	-	-	-	S	-	-	-	Peptidase, M23
PFPHHAOO_00383	0.0	-	-	-	M	-	-	-	NlpC/P60 family
PFPHHAOO_00384	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
PFPHHAOO_00385	9.71e-301	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
PFPHHAOO_00386	3.74e-232	yueF	-	-	S	-	-	-	AI-2E family transporter
PFPHHAOO_00387	0.0	csd1	3.5.1.28	-	M	ko:K01447,ko:K17733,ko:K19117	-	ko00000,ko01000,ko01002,ko01011,ko02048	N-Acetylmuramoyl-L-alanine amidase
PFPHHAOO_00389	7.69e-75	-	-	-	-	-	-	-	-
PFPHHAOO_00390	3.48e-85	-	-	-	-	-	-	-	-
PFPHHAOO_00391	1.29e-37	-	-	-	-	-	-	-	-
PFPHHAOO_00392	1.29e-194	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
PFPHHAOO_00393	9.68e-159	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
PFPHHAOO_00394	1.95e-131	-	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
PFPHHAOO_00395	1.5e-91	-	-	-	-	-	-	-	-
PFPHHAOO_00396	0.0	XK27_00340	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
PFPHHAOO_00397	1.87e-132	-	-	-	L	-	-	-	nuclease
PFPHHAOO_00398	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
PFPHHAOO_00399	3.9e-266	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
PFPHHAOO_00400	1.97e-183	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
PFPHHAOO_00401	0.0	snf	-	-	KL	-	-	-	domain protein
PFPHHAOO_00403	2.74e-50	-	-	-	-	ko:K18829	-	ko00000,ko02048	-
PFPHHAOO_00404	5.1e-89	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	Toxin-antitoxin system, toxin component, MazF family
PFPHHAOO_00406	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
PFPHHAOO_00407	1.32e-219	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
PFPHHAOO_00408	1.39e-232	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
PFPHHAOO_00409	3.75e-45	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
PFPHHAOO_00410	5.09e-302	-	-	-	L	-	-	-	Transposase
PFPHHAOO_00411	5.37e-74	-	-	-	S	-	-	-	Small secreted protein
PFPHHAOO_00412	5.52e-71	ytpP	-	-	CO	-	-	-	Thioredoxin
PFPHHAOO_00413	1.15e-152	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PFPHHAOO_00414	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
PFPHHAOO_00415	4.56e-154	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
PFPHHAOO_00416	1.61e-93	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
PFPHHAOO_00417	2.26e-21	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
PFPHHAOO_00418	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PFPHHAOO_00419	5.3e-202	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
PFPHHAOO_00420	5.43e-125	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
PFPHHAOO_00421	2.82e-105	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PFPHHAOO_00422	7.42e-296	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
PFPHHAOO_00423	8.6e-222	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
PFPHHAOO_00424	1.07e-110	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PFPHHAOO_00425	1.82e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
PFPHHAOO_00426	5.46e-74	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PFPHHAOO_00427	5.09e-302	-	-	-	L	-	-	-	Transposase
PFPHHAOO_00428	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
PFPHHAOO_00429	2.07e-303	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
PFPHHAOO_00430	1.07e-237	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
PFPHHAOO_00431	6.71e-92	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
PFPHHAOO_00432	1e-31	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
PFPHHAOO_00433	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
PFPHHAOO_00434	2.57e-169	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
PFPHHAOO_00435	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
PFPHHAOO_00436	3.1e-213	-	-	-	G	-	-	-	Phosphotransferase enzyme family
PFPHHAOO_00437	1.88e-101	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
PFPHHAOO_00438	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PFPHHAOO_00439	1.94e-68	-	-	-	-	-	-	-	-
PFPHHAOO_00440	1.31e-162	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
PFPHHAOO_00441	1.89e-228	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
PFPHHAOO_00442	3.36e-77	-	-	-	-	-	-	-	-
PFPHHAOO_00443	6.51e-220	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
PFPHHAOO_00445	1.18e-253	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
PFPHHAOO_00446	0.0	pepD3	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
PFPHHAOO_00447	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
PFPHHAOO_00448	2.2e-273	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
PFPHHAOO_00449	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
PFPHHAOO_00450	3.69e-114	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PFPHHAOO_00451	7.6e-246	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
PFPHHAOO_00452	1.04e-83	-	-	-	-	-	-	-	-
PFPHHAOO_00453	3.13e-225	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
PFPHHAOO_00454	2.63e-210	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PFPHHAOO_00455	1.38e-77	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PFPHHAOO_00456	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PFPHHAOO_00457	7.97e-65	ylxQ	-	-	J	-	-	-	ribosomal protein
PFPHHAOO_00458	5.93e-60	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
PFPHHAOO_00459	3.39e-274	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
PFPHHAOO_00460	6.36e-108	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
PFPHHAOO_00461	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PFPHHAOO_00462	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
PFPHHAOO_00463	9.45e-298	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
PFPHHAOO_00464	5.83e-178	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
PFPHHAOO_00465	1.29e-182	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PFPHHAOO_00466	3.48e-122	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
PFPHHAOO_00467	1.28e-166	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
PFPHHAOO_00468	1.82e-196	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PFPHHAOO_00469	2.91e-183	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
PFPHHAOO_00470	1.62e-230	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PFPHHAOO_00471	9.65e-65	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
PFPHHAOO_00472	5.67e-180	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
PFPHHAOO_00473	7.51e-152	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
PFPHHAOO_00474	1.6e-40	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
PFPHHAOO_00475	2.7e-47	ynzC	-	-	S	-	-	-	UPF0291 protein
PFPHHAOO_00476	2.52e-148	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PFPHHAOO_00477	5.32e-266	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
PFPHHAOO_00478	7.21e-164	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PFPHHAOO_00480	1.26e-121	-	-	-	-	-	-	-	-
PFPHHAOO_00481	5.09e-119	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PFPHHAOO_00482	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
PFPHHAOO_00483	9.7e-198	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
PFPHHAOO_00484	2.79e-225	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
PFPHHAOO_00485	1.69e-314	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PFPHHAOO_00486	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
PFPHHAOO_00487	4.93e-20	-	-	-	-	-	-	-	-
PFPHHAOO_00488	1.11e-78	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
PFPHHAOO_00489	2.01e-139	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
PFPHHAOO_00490	2.06e-297	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PFPHHAOO_00491	3.2e-302	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
PFPHHAOO_00492	4.94e-288	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PFPHHAOO_00493	1.25e-208	-	-	-	S	-	-	-	Tetratricopeptide repeat
PFPHHAOO_00494	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PFPHHAOO_00495	1.74e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PFPHHAOO_00496	1.44e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
PFPHHAOO_00497	2.27e-200	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
PFPHHAOO_00498	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
PFPHHAOO_00499	2.47e-116	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
PFPHHAOO_00500	4.83e-138	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
PFPHHAOO_00501	8.27e-250	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
PFPHHAOO_00502	3.05e-116	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PFPHHAOO_00503	4.59e-127	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
PFPHHAOO_00504	6.37e-60	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
PFPHHAOO_00505	1.07e-283	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
PFPHHAOO_00506	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
PFPHHAOO_00507	4.59e-173	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
PFPHHAOO_00508	1.32e-59	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
PFPHHAOO_00509	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
PFPHHAOO_00510	1.23e-310	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
PFPHHAOO_00511	1.34e-231	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
PFPHHAOO_00512	6.71e-265	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
PFPHHAOO_00513	2.78e-132	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
PFPHHAOO_00514	3.66e-103	-	-	-	-	-	-	-	-
PFPHHAOO_00515	9.99e-44	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
PFPHHAOO_00516	4.14e-230	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic
PFPHHAOO_00517	4.37e-39	-	-	-	-	-	-	-	-
PFPHHAOO_00518	2.51e-217	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
PFPHHAOO_00520	2.15e-75	-	-	-	-	-	-	-	-
PFPHHAOO_00521	3.74e-265	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
PFPHHAOO_00522	6.34e-279	yojA	-	-	EG	ko:K03299	-	ko00000,ko02000	GntP family permease
PFPHHAOO_00523	5.77e-104	-	-	-	KT	ko:K02647	-	ko00000,ko03000	Putative sugar diacid recognition
PFPHHAOO_00524	4.47e-255	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PFPHHAOO_00525	5.91e-279	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
PFPHHAOO_00526	1.56e-181	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
PFPHHAOO_00527	1.09e-221	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PFPHHAOO_00528	2.32e-283	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
PFPHHAOO_00529	4.39e-110	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
PFPHHAOO_00530	1.09e-309	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
PFPHHAOO_00531	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
PFPHHAOO_00532	2.6e-233	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PFPHHAOO_00533	3.49e-222	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PFPHHAOO_00534	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
PFPHHAOO_00535	5.21e-155	-	-	-	S	-	-	-	repeat protein
PFPHHAOO_00536	5.71e-159	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
PFPHHAOO_00537	8.77e-286	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
PFPHHAOO_00538	5.58e-76	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
PFPHHAOO_00539	4.48e-278	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
PFPHHAOO_00540	6.59e-160	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PFPHHAOO_00541	1.19e-25	-	-	-	-	-	-	-	-
PFPHHAOO_00542	1.44e-128	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
PFPHHAOO_00543	5.69e-44	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
PFPHHAOO_00544	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PFPHHAOO_00545	3.1e-101	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
PFPHHAOO_00546	1.76e-188	ylmH	-	-	S	-	-	-	S4 domain protein
PFPHHAOO_00547	3.2e-54	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
PFPHHAOO_00548	4.51e-92	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
PFPHHAOO_00549	8.44e-284	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PFPHHAOO_00550	0.0	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
PFPHHAOO_00551	5.77e-184	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
PFPHHAOO_00552	1.98e-258	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PFPHHAOO_00553	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PFPHHAOO_00554	7.73e-230	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PFPHHAOO_00555	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
PFPHHAOO_00556	2.85e-72	ftsL	-	-	D	-	-	-	Cell division protein FtsL
PFPHHAOO_00557	1.04e-220	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
PFPHHAOO_00558	1.5e-101	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
PFPHHAOO_00559	5.06e-77	-	-	-	-	-	-	-	-
PFPHHAOO_00560	4.47e-16	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
PFPHHAOO_00561	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
PFPHHAOO_00562	1.53e-123	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
PFPHHAOO_00563	2.24e-203	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
PFPHHAOO_00564	1.88e-251	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
PFPHHAOO_00566	2.8e-81	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
PFPHHAOO_00567	3.44e-12	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
PFPHHAOO_00568	2.03e-141	-	-	-	L	-	-	-	Bacterial dnaA protein
PFPHHAOO_00569	6.08e-171	-	-	-	L	-	-	-	Integrase core domain
PFPHHAOO_00570	1.19e-188	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
PFPHHAOO_00571	5.09e-302	-	-	-	L	-	-	-	Transposase
PFPHHAOO_00572	1.59e-14	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
PFPHHAOO_00573	4.35e-76	-	2.1.1.72, 3.1.21.3	AA10,CBM73	M	ko:K01154,ko:K02014,ko:K03933,ko:K07316	-	ko00000,ko01000,ko02000,ko02048	domain protein
PFPHHAOO_00574	6.19e-16	-	2.1.1.72, 3.1.21.3	AA10,CBM73	M	ko:K01154,ko:K02014,ko:K03933,ko:K07316	-	ko00000,ko01000,ko02000,ko02048	domain protein
PFPHHAOO_00575	1.79e-18	-	2.1.1.72, 3.1.21.3	AA10,CBM73	M	ko:K01154,ko:K02014,ko:K03933,ko:K07316	-	ko00000,ko01000,ko02000,ko02048	domain protein
PFPHHAOO_00576	4.37e-23	-	-	-	S	-	-	-	YSIRK type signal peptide
PFPHHAOO_00577	7.53e-157	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
PFPHHAOO_00578	3.29e-279	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
PFPHHAOO_00579	3.83e-175	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PFPHHAOO_00580	2.89e-100	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
PFPHHAOO_00582	4.08e-176	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
PFPHHAOO_00583	0.0	yhaN	-	-	L	-	-	-	AAA domain
PFPHHAOO_00584	1.11e-283	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
PFPHHAOO_00585	2.42e-64	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
PFPHHAOO_00586	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
PFPHHAOO_00587	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
PFPHHAOO_00588	6.15e-194	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
PFPHHAOO_00589	2.15e-210	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
PFPHHAOO_00591	2.47e-53	-	-	-	-	-	-	-	-
PFPHHAOO_00592	1.88e-60	-	-	-	-	-	-	-	-
PFPHHAOO_00593	6.22e-266	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydropteroate synthase
PFPHHAOO_00594	1.12e-131	folQ	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
PFPHHAOO_00595	8.72e-280	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
PFPHHAOO_00596	1.94e-135	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
PFPHHAOO_00597	1.46e-117	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
PFPHHAOO_00598	8.28e-73	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PFPHHAOO_00599	5.19e-90	-	-	-	-	-	-	-	-
PFPHHAOO_00601	9.17e-59	-	-	-	-	-	-	-	-
PFPHHAOO_00602	8.99e-141	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
PFPHHAOO_00603	2.54e-42	-	-	-	-	-	-	-	-
PFPHHAOO_00604	1.7e-209	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PFPHHAOO_00605	8.79e-239	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
PFPHHAOO_00606	1.53e-146	-	-	-	-	-	-	-	-
PFPHHAOO_00607	3.06e-150	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
PFPHHAOO_00608	1.4e-225	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
PFPHHAOO_00609	2.18e-112	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
PFPHHAOO_00610	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
PFPHHAOO_00611	9.73e-194	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PFPHHAOO_00612	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
PFPHHAOO_00613	1.02e-55	-	-	-	-	-	-	-	-
PFPHHAOO_00614	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
PFPHHAOO_00615	2.71e-280	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PFPHHAOO_00616	1.28e-120	tag1	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
PFPHHAOO_00617	0.0	-	-	-	EGP	-	-	-	Major Facilitator
PFPHHAOO_00618	1.46e-110	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
PFPHHAOO_00619	2.01e-302	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
PFPHHAOO_00620	1.88e-131	-	-	-	V	-	-	-	VanZ like family
PFPHHAOO_00621	7.03e-33	-	-	-	-	-	-	-	-
PFPHHAOO_00622	6.49e-228	-	-	-	L	-	-	-	Transposase DDE domain
PFPHHAOO_00624	6.49e-228	-	-	-	L	-	-	-	Transposase DDE domain
PFPHHAOO_00626	3.02e-161	bamA	-	-	GM	ko:K07277,ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko02000,ko03016,ko03019,ko03029	domain, Protein
PFPHHAOO_00627	0.0	-	-	-	J	-	-	-	Elongation factor G, domain IV
PFPHHAOO_00628	6.49e-228	-	-	-	L	-	-	-	Transposase DDE domain
PFPHHAOO_00629	1.35e-186	-	-	-	C	-	-	-	NADH flavin oxidoreductases, Old Yellow Enzyme family
PFPHHAOO_00630	9.5e-110	-	-	-	P	-	-	-	Putative esterase
PFPHHAOO_00631	5.43e-120	-	-	-	I	-	-	-	acetylesterase activity
PFPHHAOO_00632	4.71e-63	-	-	-	C	-	-	-	Flavodoxin
PFPHHAOO_00633	7.46e-105	-	-	-	P	-	-	-	esterase
PFPHHAOO_00635	3.97e-75	-	-	-	C	-	-	-	Flavodoxin
PFPHHAOO_00636	7.03e-29	-	-	-	P	-	-	-	FAD-binding domain
PFPHHAOO_00637	2.54e-19	-	-	-	P	-	-	-	FAD-binding domain
PFPHHAOO_00638	1.04e-39	-	-	-	P	-	-	-	FAD-binding domain
PFPHHAOO_00639	1.04e-91	-	-	-	C	-	-	-	Flavodoxin
PFPHHAOO_00640	3.75e-103	-	-	-	C	-	-	-	Flavodoxin
PFPHHAOO_00641	1.99e-70	-	-	-	K	-	-	-	Transcriptional regulator
PFPHHAOO_00642	1.02e-90	adhR	-	-	K	-	-	-	helix_turn_helix, mercury resistance
PFPHHAOO_00643	1.78e-242	adh2	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
PFPHHAOO_00644	7.07e-181	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PFPHHAOO_00645	1.69e-155	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
PFPHHAOO_00648	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PFPHHAOO_00649	3.6e-208	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
PFPHHAOO_00650	1.23e-135	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
PFPHHAOO_00651	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PFPHHAOO_00652	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PFPHHAOO_00653	1.02e-103	-	-	-	F	-	-	-	NUDIX domain
PFPHHAOO_00654	7.36e-222	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
PFPHHAOO_00655	6.48e-34	-	-	-	S	-	-	-	Belongs to the HesB IscA family
PFPHHAOO_00656	1.96e-35	-	-	-	-	-	-	-	-
PFPHHAOO_00658	8.23e-112	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
PFPHHAOO_00659	1.57e-80	asp1	-	-	S	-	-	-	Asp23 family, cell envelope-related function
PFPHHAOO_00660	6.23e-35	-	-	-	-	-	-	-	-
PFPHHAOO_00661	3.66e-121	-	-	-	-	-	-	-	-
PFPHHAOO_00662	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
PFPHHAOO_00663	3.78e-230	-	-	-	K	ko:K02525	-	ko00000,ko03000	Transcriptional regulator, LacI family
PFPHHAOO_00664	1.55e-294	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
PFPHHAOO_00665	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
PFPHHAOO_00666	2.93e-125	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
PFPHHAOO_00667	5.09e-302	-	-	-	L	-	-	-	Transposase
PFPHHAOO_00668	6.49e-228	-	-	-	L	-	-	-	Transposase DDE domain
PFPHHAOO_00669	5.49e-52	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
PFPHHAOO_00670	7.46e-41	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
PFPHHAOO_00671	1.46e-118	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
PFPHHAOO_00672	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PFPHHAOO_00673	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
PFPHHAOO_00674	1.13e-223	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PFPHHAOO_00675	2.39e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF3042)
PFPHHAOO_00676	1.09e-87	yqhL	-	-	P	-	-	-	Rhodanese-like protein
PFPHHAOO_00677	1.02e-234	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
PFPHHAOO_00678	7.07e-48	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
PFPHHAOO_00679	1.76e-26	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
PFPHHAOO_00680	5.07e-96	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
PFPHHAOO_00681	1.38e-131	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PFPHHAOO_00682	1.53e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
PFPHHAOO_00683	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
PFPHHAOO_00684	0.0	-	-	-	S	-	-	-	membrane
PFPHHAOO_00685	2.13e-88	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
PFPHHAOO_00686	3.52e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PFPHHAOO_00687	2.8e-150	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
PFPHHAOO_00688	1.9e-145	-	-	-	M	-	-	-	PFAM NLP P60 protein
PFPHHAOO_00689	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PFPHHAOO_00690	3.66e-252	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PFPHHAOO_00691	1.37e-76	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
PFPHHAOO_00692	2.17e-118	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
PFPHHAOO_00693	1.1e-185	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PFPHHAOO_00694	2.36e-56	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
PFPHHAOO_00695	2.25e-214	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PFPHHAOO_00696	1.52e-89	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
PFPHHAOO_00697	1.02e-295	-	-	-	V	-	-	-	MatE
PFPHHAOO_00698	0.0	potE	-	-	E	-	-	-	Amino Acid
PFPHHAOO_00699	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
PFPHHAOO_00700	1.38e-155	csrR	-	-	K	-	-	-	response regulator
PFPHHAOO_00701	7.21e-39	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
PFPHHAOO_00702	1.01e-129	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
PFPHHAOO_00703	4.94e-267	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
PFPHHAOO_00704	8.35e-175	yqeM	-	-	Q	-	-	-	Methyltransferase
PFPHHAOO_00705	1.9e-79	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
PFPHHAOO_00706	4.03e-143	yqeK	-	-	H	-	-	-	Hydrolase, HD family
PFPHHAOO_00707	6.68e-156	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PFPHHAOO_00708	5.4e-63	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
PFPHHAOO_00709	7.72e-279	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
PFPHHAOO_00710	2.23e-124	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
PFPHHAOO_00711	4.48e-205	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
PFPHHAOO_00712	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
PFPHHAOO_00713	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
PFPHHAOO_00714	3.7e-204	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
PFPHHAOO_00715	4.93e-123	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
PFPHHAOO_00716	5.7e-114	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PFPHHAOO_00717	1.84e-155	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
PFPHHAOO_00718	3.08e-207	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
PFPHHAOO_00719	8.28e-177	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
PFPHHAOO_00720	3.7e-192	-	-	-	G	-	-	-	Right handed beta helix region
PFPHHAOO_00721	0.0	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
PFPHHAOO_00722	1.18e-159	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
PFPHHAOO_00723	2.96e-209	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
PFPHHAOO_00724	2.42e-298	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PFPHHAOO_00725	9.43e-56	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
PFPHHAOO_00726	1.11e-301	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PFPHHAOO_00727	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
PFPHHAOO_00728	2.44e-84	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
PFPHHAOO_00729	6.59e-90	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
PFPHHAOO_00730	0.0	spoIIQ	-	-	M	ko:K06386	-	ko00000	Peptidase family M23
PFPHHAOO_00731	5.77e-79	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
PFPHHAOO_00733	8.91e-102	-	-	-	D	-	-	-	nuclear chromosome segregation
PFPHHAOO_00734	7.31e-18	-	-	-	S	-	-	-	AAA ATPase domain
PFPHHAOO_00735	2.12e-44	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
PFPHHAOO_00736	3.09e-16	-	-	-	-	-	-	-	-
PFPHHAOO_00737	1.79e-123	-	-	-	L	-	-	-	Helix-turn-helix domain
PFPHHAOO_00738	1.44e-170	-	-	-	O	-	-	-	Bacterial dnaA protein
PFPHHAOO_00741	1.44e-170	-	-	-	O	-	-	-	Bacterial dnaA protein
PFPHHAOO_00747	2.61e-148	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
PFPHHAOO_00748	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
PFPHHAOO_00749	2.32e-06	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
PFPHHAOO_00750	3.13e-150	-	-	-	I	-	-	-	phosphatase
PFPHHAOO_00751	8.68e-106	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
PFPHHAOO_00752	2.85e-164	-	-	-	S	-	-	-	Putative threonine/serine exporter
PFPHHAOO_00753	2.54e-42	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
PFPHHAOO_00754	3.16e-159	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
PFPHHAOO_00755	1.58e-209	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
PFPHHAOO_00756	2.99e-151	-	-	-	S	-	-	-	membrane
PFPHHAOO_00757	7.81e-141	-	-	-	S	-	-	-	VIT family
PFPHHAOO_00758	4.83e-108	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
PFPHHAOO_00759	1.39e-173	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
PFPHHAOO_00760	3.85e-195	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PFPHHAOO_00761	5.24e-143	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PFPHHAOO_00762	1.48e-140	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PFPHHAOO_00763	8.11e-282	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
PFPHHAOO_00764	5.09e-302	-	-	-	L	-	-	-	Transposase
PFPHHAOO_00765	1.44e-170	-	-	-	O	-	-	-	Bacterial dnaA protein
PFPHHAOO_00766	4.5e-288	-	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
PFPHHAOO_00767	1.56e-312	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
PFPHHAOO_00768	2.77e-306	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
PFPHHAOO_00769	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
PFPHHAOO_00770	3.34e-215	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
PFPHHAOO_00771	8.51e-214	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
PFPHHAOO_00772	1.08e-168	yceF	-	-	P	ko:K05794	-	ko00000	membrane
PFPHHAOO_00773	6.46e-74	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
PFPHHAOO_00774	4.19e-300	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
PFPHHAOO_00775	4.63e-74	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
PFPHHAOO_00776	2.98e-123	-	-	-	P	-	-	-	Cadmium resistance transporter
PFPHHAOO_00777	5.63e-177	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PFPHHAOO_00778	1.18e-196	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
PFPHHAOO_00779	7.44e-232	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
PFPHHAOO_00780	1.46e-156	-	-	-	M	-	-	-	PFAM NLP P60 protein
PFPHHAOO_00782	3.12e-130	-	-	-	S	-	-	-	Protein of unknown function (DUF3278)
PFPHHAOO_00783	5.78e-39	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix domain
PFPHHAOO_00784	4.48e-90	moaC	4.6.1.17	-	H	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
PFPHHAOO_00785	3.35e-59	-	-	-	S	-	-	-	Pfam:DUF59
PFPHHAOO_00786	8.08e-216	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
PFPHHAOO_00787	0.0	-	-	-	J	-	-	-	Elongation factor G, domain IV
PFPHHAOO_00788	2.23e-113	allC	3.5.3.9	-	E	ko:K02083	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000,ko01002	Peptidase family M20/M25/M40
PFPHHAOO_00791	1.12e-150	-	-	-	-	-	-	-	-
PFPHHAOO_00794	1.45e-26	-	-	-	S	-	-	-	Excisionase from transposon Tn916
PFPHHAOO_00795	2.66e-214	int7	-	-	L	-	-	-	Belongs to the 'phage' integrase family
PFPHHAOO_00796	6.04e-109	-	-	-	-	-	-	-	-
PFPHHAOO_00797	0.0	-	-	-	J	-	-	-	Elongation factor G, domain IV
PFPHHAOO_00798	1e-28	-	-	-	K	-	-	-	sequence-specific DNA binding
PFPHHAOO_00799	7.94e-199	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
PFPHHAOO_00800	0.0	-	-	-	LV	-	-	-	site-specific DNA-methyltransferase (adenine-specific) activity
PFPHHAOO_00801	6.49e-228	-	-	-	L	-	-	-	Transposase DDE domain
PFPHHAOO_00802	1.79e-176	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
PFPHHAOO_00803	3.22e-189	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
PFPHHAOO_00804	5.47e-151	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
PFPHHAOO_00805	1.61e-291	-	-	-	P	-	-	-	Chloride transporter, ClC family
PFPHHAOO_00806	6.89e-171	-	-	-	L	-	-	-	PFAM transposase IS116 IS110 IS902
PFPHHAOO_00807	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
PFPHHAOO_00808	4.64e-142	-	-	-	I	-	-	-	Acid phosphatase homologues
PFPHHAOO_00809	2.33e-50	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
PFPHHAOO_00810	5.04e-113	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
PFPHHAOO_00811	3.7e-19	-	-	-	-	-	-	-	-
PFPHHAOO_00812	1.79e-266	thiP	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
PFPHHAOO_00813	1.67e-119	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
PFPHHAOO_00814	4.89e-122	-	-	-	K	-	-	-	PFAM GCN5-related N-acetyltransferase
PFPHHAOO_00815	6.65e-104	-	-	-	-	-	-	-	-
PFPHHAOO_00816	3.75e-175	-	-	-	M	-	-	-	Lysin motif
PFPHHAOO_00817	4.24e-252	-	-	-	EGP	-	-	-	Major Facilitator
PFPHHAOO_00818	2.74e-50	-	-	-	D	-	-	-	Antitoxin component of a toxin-antitoxin (TA) module
PFPHHAOO_00819	1.38e-65	-	-	-	S	-	-	-	ParE toxin of type II toxin-antitoxin system, parDE
PFPHHAOO_00820	1.25e-122	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
PFPHHAOO_00821	1.2e-205	-	-	-	J	-	-	-	Methyltransferase
PFPHHAOO_00822	5.16e-289	oxlT	-	-	P	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
PFPHHAOO_00823	4.25e-183	-	-	-	V	-	-	-	DNA restriction-modification system
PFPHHAOO_00824	0.0	-	-	-	G	-	-	-	Major Facilitator Superfamily
PFPHHAOO_00825	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
PFPHHAOO_00826	4.03e-208	add	3.5.4.2, 3.5.4.4	-	F	ko:K01488,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko01000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
PFPHHAOO_00827	1.64e-233	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
PFPHHAOO_00828	0.0	ade	-	-	F	-	-	-	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
PFPHHAOO_00829	2.82e-98	-	-	-	L	-	-	-	Helix-turn-helix domain
PFPHHAOO_00830	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
PFPHHAOO_00831	4.67e-39	-	-	-	-	-	-	-	-
PFPHHAOO_00832	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
PFPHHAOO_00833	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PFPHHAOO_00834	7.93e-242	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
PFPHHAOO_00835	4.3e-96	-	-	-	S	ko:K04750	-	ko00000	3-demethylubiquinone-9 3-methyltransferase
PFPHHAOO_00836	3.16e-107	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
PFPHHAOO_00837	1.79e-302	yhdP	-	-	S	-	-	-	Transporter associated domain
PFPHHAOO_00838	8.05e-198	-	-	-	V	-	-	-	(ABC) transporter
PFPHHAOO_00839	9.43e-116	-	-	-	GM	-	-	-	epimerase
PFPHHAOO_00840	5.04e-116	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
PFPHHAOO_00841	8.16e-103	yybA	-	-	K	-	-	-	Transcriptional regulator
PFPHHAOO_00842	3.53e-169	XK27_07210	-	-	S	-	-	-	B3 4 domain
PFPHHAOO_00843	4.09e-235	XK27_12525	-	-	S	-	-	-	AI-2E family transporter
PFPHHAOO_00844	8.07e-199	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
PFPHHAOO_00845	8.24e-205	-	-	-	-	-	-	-	-
PFPHHAOO_00846	9.82e-173	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
PFPHHAOO_00847	4.02e-177	eutJ	-	-	E	ko:K04024	-	ko00000	Hsp70 protein
PFPHHAOO_00848	1.69e-202	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
PFPHHAOO_00849	2.33e-50	-	-	-	CQ	-	-	-	BMC
PFPHHAOO_00850	3.41e-170	pduB	-	-	E	-	-	-	BMC
PFPHHAOO_00851	0.0	pduC	4.2.1.28	-	Q	ko:K01699	ko00640,map00640	ko00000,ko00001,ko01000	Dehydratase large subunit
PFPHHAOO_00852	5e-162	pduD	4.2.1.28	-	Q	ko:K13919	ko00640,map00640	ko00000,ko00001,ko01000	Dehydratase medium subunit
PFPHHAOO_00853	8.85e-97	pduE	4.2.1.28	-	Q	ko:K13920	ko00640,map00640	ko00000,ko00001,ko01000	Dehydratase small subunit
PFPHHAOO_00854	0.0	pduG	-	-	D	-	-	-	Diol dehydratase reactivase ATPase-like domain
PFPHHAOO_00855	1.31e-59	pduH	-	-	S	-	-	-	Dehydratase medium subunit
PFPHHAOO_00856	9.33e-75	-	-	-	CQ	-	-	-	BMC
PFPHHAOO_00857	3.65e-53	pduA_2	-	-	CQ	ko:K04027	-	ko00000	BMC
PFPHHAOO_00858	1.98e-148	pduL	2.3.1.222	-	Q	ko:K13923	ko00640,map00640	ko00000,ko00001,ko01000	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate
PFPHHAOO_00859	1.25e-103	-	-	-	S	-	-	-	Putative propanediol utilisation
PFPHHAOO_00860	5.63e-55	pduN	-	-	CQ	ko:K04028	-	ko00000	Ethanolamine utilisation protein EutN/carboxysome
PFPHHAOO_00861	2.85e-134	-	-	-	S	-	-	-	Cobalamin adenosyltransferase
PFPHHAOO_00862	1.62e-101	pduO	-	-	S	-	-	-	Haem-degrading
PFPHHAOO_00863	0.0	pduP	1.2.1.87	-	C	ko:K13922	ko00640,map00640	ko00000,ko00001,ko01000	Aldehyde dehydrogenase family
PFPHHAOO_00864	4.33e-259	pduQ	-	-	C	ko:K13921	ko00640,map00640	ko00000,ko00001	Iron-containing alcohol dehydrogenase
PFPHHAOO_00865	2.5e-278	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PFPHHAOO_00866	9.15e-72	-	-	-	E	ko:K04031	-	ko00000	BMC
PFPHHAOO_00867	7.99e-150	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Pfam:Y_phosphatase3C
PFPHHAOO_00868	3.03e-96	pgm1	-	-	G	-	-	-	phosphoglycerate mutase
PFPHHAOO_00869	3.45e-87	-	-	-	P	-	-	-	Cadmium resistance transporter
PFPHHAOO_00870	1.44e-90	eutP	-	-	E	ko:K04029	-	ko00000	Ethanolamine utilisation - propanediol utilisation
PFPHHAOO_00871	6.45e-95	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
PFPHHAOO_00872	4.92e-147	nqo1	-	-	S	ko:K19784	-	ko00000	NADPH-dependent FMN reductase
PFPHHAOO_00873	1.72e-102	yvqK	2.5.1.17	-	S	ko:K00798	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Cobalamin adenosyltransferase
PFPHHAOO_00874	2.83e-215	cobD	4.1.1.81	-	E	ko:K04720	ko00860,map00860	ko00000,ko00001,ko01000	Aminotransferase class I and II
PFPHHAOO_00875	2.22e-256	cbiA	6.3.5.11, 6.3.5.9	-	F	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source
PFPHHAOO_00876	4.35e-186	cobD	6.3.1.10	-	H	ko:K02227	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
PFPHHAOO_00877	5.48e-139	cbiC	5.4.99.60, 5.4.99.61	-	H	ko:K06042	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Precorrin-8X methylmutase
PFPHHAOO_00878	1.39e-244	cbiD	2.1.1.195	-	H	ko:K02188	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
PFPHHAOO_00879	6.19e-102	cbiE	2.1.1.289	-	H	ko:K03399	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
PFPHHAOO_00880	7.05e-100	cbiT	2.1.1.196	-	H	ko:K02191	ko00860,map00860	ko00000,ko00001,ko01000	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
PFPHHAOO_00881	5.75e-165	cbiF	2.1.1.133, 2.1.1.271	-	H	ko:K05936	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
PFPHHAOO_00882	3.13e-181	cbiG	3.7.1.12	-	H	ko:K02189	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Cobalamin synthesis G C-terminus
PFPHHAOO_00883	2.29e-165	cbiH	2.1.1.131	-	H	ko:K05934	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
PFPHHAOO_00884	1.51e-125	cobK	1.3.1.106, 1.3.1.54	-	H	ko:K05895	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Precorrin-6x reductase CbiJ/CobK
PFPHHAOO_00885	1.2e-223	cobA	2.1.1.107, 4.2.1.75	-	H	ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
PFPHHAOO_00886	1.97e-138	cbiK	4.99.1.3	-	H	ko:K02190	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Cobalt chelatase (CbiK)
PFPHHAOO_00887	5.52e-117	cbiL	2.1.1.130, 2.1.1.151	-	H	ko:K03394	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
PFPHHAOO_00888	3.86e-158	cbiM	-	-	P	ko:K02007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
PFPHHAOO_00889	8.36e-59	cbiN	-	-	P	ko:K02009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
PFPHHAOO_00890	1.88e-131	cbiQ	-	-	P	ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
PFPHHAOO_00891	7.19e-155	cbiO	-	-	P	ko:K02006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	part of an ABC transporter complex. Responsible for energy coupling to the transport system
PFPHHAOO_00892	9.25e-301	cobQ	6.3.5.10	-	H	ko:K02232	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
PFPHHAOO_00893	5.47e-75	cysG	1.3.1.76, 4.99.1.4	-	H	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Putative NAD(P)-binding
PFPHHAOO_00894	1.34e-245	hemA	1.2.1.70	-	H	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
PFPHHAOO_00895	4.41e-172	hemC	2.5.1.61	-	H	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
PFPHHAOO_00896	2.77e-223	hemB	4.2.1.24	-	H	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko04147	Delta-aminolevulinic acid dehydratase
PFPHHAOO_00897	2.26e-304	hemL	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
PFPHHAOO_00898	1.41e-98	cobU	2.7.1.156, 2.7.7.62	-	H	ko:K02231	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Cobinamide kinase / cobinamide phosphate guanyltransferase
PFPHHAOO_00899	2.56e-152	cobS	2.7.8.26	-	H	ko:K02233	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
PFPHHAOO_00900	4.47e-95	cobC	3.1.3.73	-	G	ko:K02226	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphoglycerate mutase family
PFPHHAOO_00901	1.1e-91	-	-	-	H	-	-	-	Uroporphyrinogen-III synthase
PFPHHAOO_00902	2.26e-185	cobT	2.4.2.21	-	F	ko:K00768	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)
PFPHHAOO_00903	3.21e-66	-	-	-	EG	-	-	-	PFAM EamA-like transporter family
PFPHHAOO_00904	5.84e-66	-	-	-	S	-	-	-	Domain of unknown function (DUF4430)
PFPHHAOO_00905	5.76e-103	-	-	-	S	ko:K16927	-	ko00000,ko00002,ko02000	ECF transporter, substrate-specific component
PFPHHAOO_00906	1.39e-232	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
PFPHHAOO_00907	1.73e-68	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
PFPHHAOO_00908	2.48e-57	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PFPHHAOO_00909	1.73e-215	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
PFPHHAOO_00910	5.18e-291	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
PFPHHAOO_00911	3.54e-165	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
PFPHHAOO_00912	3.29e-282	-	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
PFPHHAOO_00913	6.41e-184	XK27_00940	3.5.1.9	-	S	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	ko00000,ko00001,ko00002,ko01000	Putative cyclase
PFPHHAOO_00914	4.67e-203	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
PFPHHAOO_00915	5.41e-227	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
PFPHHAOO_00916	0.0	lacZ	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
PFPHHAOO_00917	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
PFPHHAOO_00918	1.11e-237	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
PFPHHAOO_00919	4.91e-59	-	-	-	S	-	-	-	CRISPR-associated protein (Cas_Csn2)
PFPHHAOO_00920	7.44e-51	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
PFPHHAOO_00921	3.99e-143	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
PFPHHAOO_00922	5.71e-23	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
PFPHHAOO_00924	3.83e-70	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
PFPHHAOO_00925	4.75e-240	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
PFPHHAOO_00926	3.39e-92	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
PFPHHAOO_00927	1.39e-232	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
PFPHHAOO_00928	1.49e-69	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
PFPHHAOO_00929	0.0	-	2.4.1.5	GH13	G	ko:K00689	ko00500,ko02020,map00500,map02020	ko00000,ko00001,ko01000	Glycosyl hydrolase family 70
PFPHHAOO_00930	0.0	-	-	-	G	-	-	-	Peptidase_C39 like family
PFPHHAOO_00931	2.54e-45	-	-	-	-	-	-	-	-
PFPHHAOO_00932	4.12e-277	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
PFPHHAOO_00933	2.42e-265	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
PFPHHAOO_00934	4.89e-94	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
PFPHHAOO_00935	2.69e-109	-	-	-	-	-	-	-	-
PFPHHAOO_00936	9.63e-38	-	-	-	M	-	-	-	biosynthesis protein
PFPHHAOO_00937	1.1e-95	-	-	GT2	M	ko:K12997	-	ko00000,ko01000,ko01003,ko01005	Glycosyl transferase family 2
PFPHHAOO_00938	4.46e-84	-	-	-	S	-	-	-	Glycosyltransferase like family
PFPHHAOO_00939	4.99e-98	-	-	-	S	ko:K07011	-	ko00000	Glycosyltransferase, group 2 family protein
PFPHHAOO_00940	3.22e-89	-	-	-	S	-	-	-	Acyltransferase family
PFPHHAOO_00941	5.44e-96	-	-	-	-	-	-	-	-
PFPHHAOO_00942	4.52e-184	-	-	-	M	-	-	-	Glycosyl transferase family 2
PFPHHAOO_00943	2.46e-173	-	-	-	-	-	-	-	-
PFPHHAOO_00944	0.0	-	-	CBM50	NU	ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
PFPHHAOO_00945	1.58e-205	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
PFPHHAOO_00946	7.93e-140	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
PFPHHAOO_00947	1.15e-263	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
PFPHHAOO_00948	1.15e-263	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
PFPHHAOO_00949	7.93e-140	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
PFPHHAOO_00950	1.58e-205	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
PFPHHAOO_00951	5.65e-123	-	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
PFPHHAOO_00953	6.67e-46	-	-	-	M	-	-	-	Glycosyltransferase like family 2
PFPHHAOO_00954	4.5e-45	-	-	-	M	-	-	-	Glycosyl transferase family 2
PFPHHAOO_00955	2.27e-124	-	-	-	M	-	-	-	Glycosyl transferases group 1
PFPHHAOO_00956	1.04e-55	-	-	-	S	-	-	-	Hexapeptide repeat of succinyl-transferase
PFPHHAOO_00957	8.43e-43	wbiF	-	-	S	ko:K07011	-	ko00000	glycosyl transferase
PFPHHAOO_00958	9.5e-62	-	-	-	M	ko:K13012	-	ko00000,ko01005	Bacterial sugar transferase
PFPHHAOO_00960	3.83e-70	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
PFPHHAOO_00961	4.75e-240	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
PFPHHAOO_00962	3.39e-92	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
PFPHHAOO_00963	9.7e-162	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
PFPHHAOO_00964	8.75e-146	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PFPHHAOO_00966	1.22e-130	-	-	-	L	ko:K07482	-	ko00000	Helix-turn-helix domain
PFPHHAOO_00967	1.09e-202	panE1	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PFPHHAOO_00968	1.6e-38	-	-	-	L	-	-	-	Integrase
PFPHHAOO_00969	2.57e-67	-	-	-	L	-	-	-	Lactococcus lactis RepB C-terminus
PFPHHAOO_00971	1.32e-127	nicK	-	-	L	ko:K07467	-	ko00000	Replication initiation factor
PFPHHAOO_00972	6.74e-48	-	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-strand binding protein family
PFPHHAOO_00973	3.81e-105	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
PFPHHAOO_00977	2.56e-81	-	-	-	S	-	-	-	Initiator Replication protein
PFPHHAOO_00978	9.85e-13	-	-	-	-	-	-	-	-
PFPHHAOO_00979	1.34e-15	-	-	-	LV	-	-	-	site-specific DNA-methyltransferase (adenine-specific) activity
PFPHHAOO_00980	9.55e-43	-	-	-	S	-	-	-	Protein of unknown function (DUF2089)
PFPHHAOO_00981	3e-37	-	-	-	-	-	-	-	-
PFPHHAOO_00983	1.52e-119	-	-	-	L	-	-	-	Integrase
PFPHHAOO_00986	3.17e-243	secY2	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	SecY translocase
PFPHHAOO_00987	0.0	asp1	-	-	S	ko:K12268	-	ko00000,ko02044	Accessory Sec system protein Asp1
PFPHHAOO_00988	0.0	asp2	-	-	S	ko:K12269	-	ko00000,ko02044	Accessory Sec system GspB-transporter
PFPHHAOO_00990	0.0	secA2	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
PFPHHAOO_00992	0.0	gtf1	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
PFPHHAOO_00993	0.0	gtf2	-	-	M	-	-	-	A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
PFPHHAOO_00994	1.33e-173	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
PFPHHAOO_00995	5.14e-92	-	-	-	L	-	-	-	Helix-turn-helix domain
PFPHHAOO_00996	3.96e-16	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.87
PFPHHAOO_00998	2.03e-98	tnpR1	-	-	L	-	-	-	Resolvase, N terminal domain
PFPHHAOO_00999	9.38e-39	-	-	-	S	-	-	-	FRG
PFPHHAOO_01000	1.21e-28	-	-	-	K	-	-	-	sequence-specific DNA binding
PFPHHAOO_01001	0.0	-	-	-	J	-	-	-	Elongation factor G, domain IV
PFPHHAOO_01002	1.96e-111	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
PFPHHAOO_01003	1.7e-100	-	-	-	L	-	-	-	Phage integrase family
PFPHHAOO_01004	7.93e-07	-	-	-	S	-	-	-	Domain of unknown function (DUF3173)
PFPHHAOO_01006	2.4e-76	-	-	-	L	-	-	-	Resolvase, N terminal domain
PFPHHAOO_01012	3.39e-92	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
PFPHHAOO_01013	4.75e-240	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
PFPHHAOO_01014	3.83e-70	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
PFPHHAOO_01016	1.35e-302	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PFPHHAOO_01017	1.85e-225	-	-	-	-	-	-	-	-
PFPHHAOO_01018	5.27e-169	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PFPHHAOO_01019	9.62e-309	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
PFPHHAOO_01020	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
PFPHHAOO_01021	2.37e-135	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PFPHHAOO_01022	4.6e-249	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
PFPHHAOO_01023	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PFPHHAOO_01024	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PFPHHAOO_01025	5.68e-163	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PFPHHAOO_01026	4.5e-50	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PFPHHAOO_01027	3.53e-168	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
PFPHHAOO_01028	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PFPHHAOO_01029	7.12e-275	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PFPHHAOO_01030	8.95e-110	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PFPHHAOO_01031	7.04e-127	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
PFPHHAOO_01032	3.61e-219	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
PFPHHAOO_01033	5.9e-231	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
PFPHHAOO_01034	1.36e-30	rhaS4	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
PFPHHAOO_01035	5.74e-24	mocA	-	-	S	-	-	-	Oxidoreductase
PFPHHAOO_01036	3.66e-165	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Belongs to the alpha-acetolactate decarboxylase family
PFPHHAOO_01037	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
PFPHHAOO_01038	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
PFPHHAOO_01039	3.86e-223	ydbI	-	-	K	-	-	-	AI-2E family transporter
PFPHHAOO_01040	1.64e-291	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
PFPHHAOO_01041	2.62e-122	ribB	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PFPHHAOO_01042	3.7e-148	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
PFPHHAOO_01043	1.51e-147	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PFPHHAOO_01044	3.95e-167	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
PFPHHAOO_01045	1.87e-218	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
PFPHHAOO_01046	2.13e-313	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
PFPHHAOO_01047	2.57e-221	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
PFPHHAOO_01048	1.12e-165	-	-	-	K	-	-	-	LysR substrate binding domain
PFPHHAOO_01049	4.05e-70	-	-	-	S	-	-	-	branched-chain amino acid
PFPHHAOO_01050	9.75e-186	-	-	-	E	-	-	-	AzlC protein
PFPHHAOO_01051	3.73e-264	hpk31	-	-	T	-	-	-	Histidine kinase
PFPHHAOO_01052	9.76e-161	vanR	-	-	K	-	-	-	response regulator
PFPHHAOO_01053	1.47e-265	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
PFPHHAOO_01054	3.92e-217	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	sugar-binding domain protein
PFPHHAOO_01055	3.27e-167	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
PFPHHAOO_01056	1.58e-300	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	pyrimidine-nucleoside phosphorylase
PFPHHAOO_01057	4.64e-298	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
PFPHHAOO_01058	9.74e-154	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
PFPHHAOO_01059	6.3e-175	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
PFPHHAOO_01060	1.75e-254	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
PFPHHAOO_01061	2.37e-42	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
PFPHHAOO_01062	8e-197	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
PFPHHAOO_01063	8.34e-180	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
PFPHHAOO_01064	1.32e-193	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
PFPHHAOO_01065	9.18e-156	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
PFPHHAOO_01066	5.72e-206	-	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase
PFPHHAOO_01067	4.78e-218	rihA	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
PFPHHAOO_01068	2.4e-278	nupG	-	-	F	ko:K03317,ko:K11535,ko:K16323	-	ko00000,ko02000	Nucleoside transporter
PFPHHAOO_01069	2.51e-285	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
PFPHHAOO_01070	8.05e-178	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
PFPHHAOO_01071	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PFPHHAOO_01072	0.0	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PFPHHAOO_01073	4.91e-44	-	-	-	L	-	-	-	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
PFPHHAOO_01075	1.05e-34	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
PFPHHAOO_01076	5.04e-113	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
PFPHHAOO_01077	5.51e-49	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
PFPHHAOO_01080	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
PFPHHAOO_01081	5.86e-190	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
PFPHHAOO_01084	1.14e-145	-	-	-	-	-	-	-	-
PFPHHAOO_01085	4.55e-315	-	-	-	EGP	-	-	-	Major Facilitator
PFPHHAOO_01086	0.0	-	-	-	P	ko:K07085	-	ko00000	Predicted Permease Membrane Region
PFPHHAOO_01087	4.13e-167	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
PFPHHAOO_01088	3.54e-165	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
PFPHHAOO_01089	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PFPHHAOO_01090	1.76e-195	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
PFPHHAOO_01091	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
PFPHHAOO_01092	3.74e-108	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
PFPHHAOO_01094	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
PFPHHAOO_01095	6.15e-234	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
PFPHHAOO_01096	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
PFPHHAOO_01097	5.05e-171	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PFPHHAOO_01098	4.95e-213	-	-	-	I	-	-	-	alpha/beta hydrolase fold
PFPHHAOO_01099	5.21e-275	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
PFPHHAOO_01100	3.36e-154	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PFPHHAOO_01101	4.11e-172	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
PFPHHAOO_01102	7.93e-177	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
PFPHHAOO_01103	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
PFPHHAOO_01104	2.92e-161	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
PFPHHAOO_01105	4.04e-67	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
PFPHHAOO_01106	8.07e-128	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
PFPHHAOO_01107	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PFPHHAOO_01108	5.49e-262	yacL	-	-	S	-	-	-	domain protein
PFPHHAOO_01109	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
PFPHHAOO_01110	2.95e-92	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
PFPHHAOO_01111	1.82e-175	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PFPHHAOO_01112	9.18e-31	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
PFPHHAOO_01113	7.11e-32	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
PFPHHAOO_01114	1.1e-126	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
PFPHHAOO_01115	1.39e-92	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PFPHHAOO_01116	8.31e-158	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
PFPHHAOO_01117	2.96e-285	aadAT	-	-	EK	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000	Aminotransferase, class I
PFPHHAOO_01119	1.15e-40	-	-	-	M	-	-	-	Glycosyl transferase family group 2
PFPHHAOO_01120	6.86e-195	-	-	-	M	-	-	-	Glycosyl transferase family group 2
PFPHHAOO_01121	1.53e-268	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
PFPHHAOO_01122	3.6e-107	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PFPHHAOO_01123	2.46e-72	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
PFPHHAOO_01124	3.05e-49	-	-	-	-	-	-	-	-
PFPHHAOO_01125	3.29e-62	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
PFPHHAOO_01126	2.79e-75	XK27_06915	-	-	K	ko:K10947	-	ko00000,ko03000	transcriptional regulator PadR family
PFPHHAOO_01127	6.31e-126	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
PFPHHAOO_01128	9.28e-170	-	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
PFPHHAOO_01129	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
PFPHHAOO_01130	4.45e-253	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PFPHHAOO_01131	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PFPHHAOO_01132	9.33e-48	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
PFPHHAOO_01133	1.35e-113	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
PFPHHAOO_01134	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PFPHHAOO_01135	5.87e-62	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PFPHHAOO_01136	1.65e-140	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PFPHHAOO_01137	1.57e-50	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
PFPHHAOO_01138	3.41e-144	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PFPHHAOO_01139	1.64e-68	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
PFPHHAOO_01140	7.16e-233	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
PFPHHAOO_01141	1.77e-74	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
PFPHHAOO_01142	1.06e-198	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PFPHHAOO_01143	1.43e-174	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
PFPHHAOO_01144	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
PFPHHAOO_01145	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
PFPHHAOO_01146	7.29e-219	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
PFPHHAOO_01147	2.35e-244	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
PFPHHAOO_01148	2.56e-162	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
PFPHHAOO_01149	8e-131	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
PFPHHAOO_01150	1.13e-248	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PFPHHAOO_01151	9.93e-168	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PFPHHAOO_01152	1.22e-288	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PFPHHAOO_01153	1.48e-176	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PFPHHAOO_01154	8.63e-180	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
PFPHHAOO_01155	8.87e-289	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
PFPHHAOO_01156	2.93e-233	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PFPHHAOO_01157	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
PFPHHAOO_01158	4.67e-147	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
PFPHHAOO_01160	1.83e-59	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PFPHHAOO_01161	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
PFPHHAOO_01162	1.73e-103	-	-	-	S	ko:K19055	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
PFPHHAOO_01163	0.0	-	-	-	E	-	-	-	amino acid
PFPHHAOO_01164	0.0	ydaO	-	-	E	-	-	-	amino acid
PFPHHAOO_01165	1.53e-52	-	-	-	-	-	-	-	-
PFPHHAOO_01166	3.99e-72	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
PFPHHAOO_01167	5.26e-55	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
PFPHHAOO_01168	2.71e-103	usp5	-	-	T	-	-	-	universal stress protein
PFPHHAOO_01169	2.7e-104	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	AsnC family
PFPHHAOO_01170	5.61e-292	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
PFPHHAOO_01171	2.6e-141	apl	3.1.3.1	-	S	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	SNARE associated Golgi protein
PFPHHAOO_01172	5.68e-12	-	-	-	IQ	-	-	-	KR domain
PFPHHAOO_01173	9.4e-146	-	-	-	IQ	-	-	-	KR domain
PFPHHAOO_01174	1.47e-171	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
PFPHHAOO_01175	1.05e-127	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
PFPHHAOO_01176	3.61e-316	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
PFPHHAOO_01177	4.63e-144	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
PFPHHAOO_01178	6.5e-71	-	-	-	-	-	-	-	-
PFPHHAOO_01179	0.0	nhaK	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
PFPHHAOO_01180	2.59e-68	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
PFPHHAOO_01181	1.03e-240	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
PFPHHAOO_01182	1.3e-95	-	-	-	K	-	-	-	Transcriptional regulator
PFPHHAOO_01183	2.62e-202	-	-	-	-	-	-	-	-
PFPHHAOO_01184	5.8e-223	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
PFPHHAOO_01185	0.0	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system Galactitol-specific IIC component
PFPHHAOO_01186	3.23e-269	-	-	-	EGP	-	-	-	Major Facilitator
PFPHHAOO_01187	2.16e-173	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
PFPHHAOO_01188	1.3e-148	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
PFPHHAOO_01189	4.39e-11	-	-	-	-	-	-	-	-
PFPHHAOO_01190	1.78e-83	-	-	-	-	-	-	-	-
PFPHHAOO_01191	1e-248	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
PFPHHAOO_01192	7.46e-106	uspA3	-	-	T	-	-	-	universal stress protein
PFPHHAOO_01193	0.0	fusA1	-	-	J	-	-	-	elongation factor G
PFPHHAOO_01194	2.96e-211	-	-	-	GK	-	-	-	ROK family
PFPHHAOO_01195	6.02e-305	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
PFPHHAOO_01196	3.54e-177	yfhR3	-	-	S	ko:K06889	-	ko00000	Serine hydrolase (FSH1)
PFPHHAOO_01197	7.37e-99	-	-	-	E	-	-	-	amino acid
PFPHHAOO_01198	3.59e-147	-	-	-	E	-	-	-	amino acid
PFPHHAOO_01199	7.66e-23	-	-	-	E	-	-	-	amino acid
PFPHHAOO_01200	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
PFPHHAOO_01201	8.56e-162	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
PFPHHAOO_01202	3.07e-109	ebsC	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PFPHHAOO_01203	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
PFPHHAOO_01204	0.0	rtpR	1.17.4.2	-	F	ko:K00527	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	ribonucleoside-triphosphate reductase activity
PFPHHAOO_01205	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
PFPHHAOO_01206	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
PFPHHAOO_01207	1.16e-23	-	-	-	K	-	-	-	Winged helix-turn-helix DNA-binding
PFPHHAOO_01208	1.86e-227	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PFPHHAOO_01209	3.85e-24	-	-	-	S	-	-	-	PFAM Archaeal ATPase
PFPHHAOO_01210	1.36e-28	-	-	-	D	-	-	-	Domain of Unknown Function (DUF1542)
PFPHHAOO_01211	4.06e-56	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
PFPHHAOO_01212	3.58e-47	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
PFPHHAOO_01213	3.65e-64	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
PFPHHAOO_01214	3.63e-36	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
PFPHHAOO_01215	8.45e-149	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
PFPHHAOO_01216	1.85e-104	yjcF	3.5.4.33, 4.4.1.8	-	K	ko:K02348,ko:K07000,ko:K11991,ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007,ko03016	protein acetylation
PFPHHAOO_01217	1.36e-248	-	-	-	S	-	-	-	Protein of unknown function (DUF3114)
PFPHHAOO_01218	0.0	gshA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
PFPHHAOO_01219	2.16e-212	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
PFPHHAOO_01220	1.46e-135	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
PFPHHAOO_01221	4.62e-81	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
PFPHHAOO_01222	1.26e-243	mocA	-	-	S	-	-	-	Oxidoreductase
PFPHHAOO_01223	9.46e-298	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
PFPHHAOO_01225	2.09e-266	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
PFPHHAOO_01226	1e-72	-	-	-	-	-	-	-	-
PFPHHAOO_01227	2.45e-88	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
PFPHHAOO_01228	1.92e-102	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
PFPHHAOO_01229	4.96e-216	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
PFPHHAOO_01230	1.69e-281	arcT	-	-	E	-	-	-	Aminotransferase
PFPHHAOO_01231	0.0	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
PFPHHAOO_01232	0.0	potE	-	-	E	-	-	-	Amino Acid
PFPHHAOO_01233	5.01e-197	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
PFPHHAOO_01234	1.26e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
PFPHHAOO_01235	2.53e-42	-	-	-	-	-	-	-	-
PFPHHAOO_01236	4.55e-172	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
PFPHHAOO_01237	1.57e-188	cps1D	-	-	M	-	-	-	Domain of unknown function (DUF4422)
PFPHHAOO_01238	7.05e-219	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
PFPHHAOO_01239	2.23e-150	-	-	-	M	-	-	-	Bacterial sugar transferase
PFPHHAOO_01240	6.21e-62	ywnA	-	-	K	-	-	-	Transcriptional regulator
PFPHHAOO_01241	1.96e-53	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
PFPHHAOO_01242	2.25e-24	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
PFPHHAOO_01243	3.51e-253	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
PFPHHAOO_01244	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
PFPHHAOO_01245	2.41e-156	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
PFPHHAOO_01246	7.13e-247	-	2.7.7.65	-	T	ko:K02488	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko00002,ko01000,ko02022	GGDEF domain
PFPHHAOO_01247	3.3e-100	-	-	-	-	-	-	-	-
PFPHHAOO_01248	5.09e-302	-	-	-	L	-	-	-	Transposase
PFPHHAOO_01249	5.02e-190	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	biotin lipoate A B protein ligase
PFPHHAOO_01250	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
PFPHHAOO_01251	7.71e-189	yidA	-	-	S	-	-	-	hydrolase
PFPHHAOO_01252	1.19e-98	-	-	-	-	-	-	-	-
PFPHHAOO_01253	3.53e-229	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PFPHHAOO_01254	3.04e-312	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PFPHHAOO_01255	2.09e-190	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
PFPHHAOO_01256	1.75e-165	-	-	-	U	ko:K02075	-	ko00000,ko00002,ko02000	ABC 3 transport family
PFPHHAOO_01257	1.98e-157	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
PFPHHAOO_01258	1.93e-213	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
PFPHHAOO_01259	1.71e-206	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
PFPHHAOO_01260	2.74e-50	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
PFPHHAOO_01261	1.03e-205	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
PFPHHAOO_01262	7.04e-127	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
PFPHHAOO_01263	3.58e-198	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
PFPHHAOO_01264	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PFPHHAOO_01265	3.2e-206	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
PFPHHAOO_01267	4.85e-167	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
PFPHHAOO_01268	1.05e-225	-	-	-	-	-	-	-	-
PFPHHAOO_01269	7.91e-288	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
PFPHHAOO_01270	2.53e-214	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
PFPHHAOO_01271	2.26e-242	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
PFPHHAOO_01272	8.74e-234	-	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	Belongs to the N(4) N(6)-methyltransferase family
PFPHHAOO_01273	4.08e-106	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
PFPHHAOO_01274	0.0	-	-	-	L	-	-	-	DNA helicase
PFPHHAOO_01275	7.77e-261	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
PFPHHAOO_01277	0.0	gabT	2.6.1.19, 5.1.1.21	-	E	ko:K00823,ko:K20708	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PFPHHAOO_01278	0.0	ctrA	-	-	E	ko:K03294	-	ko00000	amino acid
PFPHHAOO_01279	1.64e-151	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PFPHHAOO_01280	5.74e-54	-	1.3.5.4	-	S	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FMN binding
PFPHHAOO_01281	1.7e-280	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	transporter
PFPHHAOO_01282	7e-215	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
PFPHHAOO_01283	5.91e-198	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
PFPHHAOO_01284	3.47e-244	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PFPHHAOO_01285	1.06e-139	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PFPHHAOO_01286	6.29e-272	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
PFPHHAOO_01287	9.39e-238	eriC	-	-	P	ko:K03281	-	ko00000	chloride
PFPHHAOO_01288	2.48e-274	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
PFPHHAOO_01289	1.12e-76	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
PFPHHAOO_01290	7.7e-104	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
PFPHHAOO_01291	1.32e-136	-	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, permease protein
PFPHHAOO_01292	3.69e-183	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
PFPHHAOO_01293	7.17e-135	proWZ	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PFPHHAOO_01294	8.79e-208	proWY	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, QAT family
PFPHHAOO_01295	3.71e-95	ywnA	-	-	K	-	-	-	Transcriptional regulator
PFPHHAOO_01296	2.68e-45	-	-	-	GM	-	-	-	NAD(P)H-binding
PFPHHAOO_01297	4.44e-11	-	-	-	-	-	-	-	-
PFPHHAOO_01298	1.4e-280	-	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Metalloenzyme superfamily
PFPHHAOO_01299	0.0	cadA	-	-	P	-	-	-	P-type ATPase
PFPHHAOO_01300	1.53e-160	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
PFPHHAOO_01301	2.12e-162	-	-	-	-	-	-	-	-
PFPHHAOO_01302	1.85e-69	-	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
PFPHHAOO_01303	7.42e-311	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
PFPHHAOO_01305	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
PFPHHAOO_01306	2.43e-105	-	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	PAP2 superfamily
PFPHHAOO_01307	7.7e-227	ydhF	-	-	S	-	-	-	Aldo keto reductase
PFPHHAOO_01309	5.03e-181	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
PFPHHAOO_01310	4.48e-37	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
PFPHHAOO_01311	3.28e-128	-	-	-	S	ko:K07002	-	ko00000	Serine hydrolase
PFPHHAOO_01313	5.64e-232	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PFPHHAOO_01314	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
PFPHHAOO_01315	2.22e-50	-	-	-	S	-	-	-	Cytochrome b5-like Heme/Steroid binding domain
PFPHHAOO_01316	9.4e-148	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
PFPHHAOO_01317	1.3e-48	-	-	-	-	-	-	-	-
PFPHHAOO_01318	1.03e-24	-	-	-	IQ	-	-	-	dehydrogenase reductase
PFPHHAOO_01319	2.98e-77	-	-	-	IQ	-	-	-	dehydrogenase reductase
PFPHHAOO_01320	6.78e-306	-	-	-	EGP	-	-	-	MFS transporter, metabolite H symporter (MHS) family protein
PFPHHAOO_01321	1.6e-19	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
PFPHHAOO_01322	6.21e-16	-	-	-	M	-	-	-	Rib/alpha-like repeat
PFPHHAOO_01323	2.2e-105	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
PFPHHAOO_01324	8.33e-186	artP	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
PFPHHAOO_01325	1.51e-126	-	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
PFPHHAOO_01326	1.33e-170	-	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
PFPHHAOO_01327	8.56e-162	-	-	-	K	-	-	-	helix_turn_helix gluconate operon transcriptional repressor
PFPHHAOO_01328	2.79e-193	frlD1	2.7.1.218	-	G	ko:K10710	-	ko00000,ko01000	pfkB family carbohydrate kinase
PFPHHAOO_01329	1.29e-231	-	-	-	G	-	-	-	Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
PFPHHAOO_01331	1.36e-227	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
PFPHHAOO_01333	8.75e-146	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PFPHHAOO_01334	9.7e-162	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
PFPHHAOO_01335	5.09e-302	-	-	-	L	-	-	-	Transposase
PFPHHAOO_01336	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PFPHHAOO_01337	8.46e-77	-	-	-	-	-	-	-	-
PFPHHAOO_01338	1.53e-97	-	-	-	K	-	-	-	MerR HTH family regulatory protein
PFPHHAOO_01339	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
PFPHHAOO_01340	1.47e-157	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
PFPHHAOO_01341	3.34e-212	yjbO	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
PFPHHAOO_01343	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PFPHHAOO_01344	7.62e-132	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
PFPHHAOO_01345	3.06e-238	-	-	-	I	-	-	-	Alpha beta
PFPHHAOO_01346	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
PFPHHAOO_01347	6.38e-151	-	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
PFPHHAOO_01348	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
PFPHHAOO_01349	1.2e-203	-	-	-	K	-	-	-	LysR family
PFPHHAOO_01350	0.0	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
PFPHHAOO_01351	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
PFPHHAOO_01352	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
PFPHHAOO_01353	0.0	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
PFPHHAOO_01354	1.44e-202	mleR	-	-	K	-	-	-	LysR family
PFPHHAOO_01355	6.76e-143	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PFPHHAOO_01356	3.86e-263	adh	1.1.1.1	-	C	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding alcohol dehydrogenase family protein
PFPHHAOO_01357	0.0	-	-	-	L	-	-	-	PFAM plasmid pRiA4b ORF-3 family protein
PFPHHAOO_01358	1.22e-204	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
PFPHHAOO_01359	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
PFPHHAOO_01360	2.33e-29	-	-	-	-	-	-	-	-
PFPHHAOO_01361	1.5e-254	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
PFPHHAOO_01362	5.36e-97	-	-	-	-	-	-	-	-
PFPHHAOO_01363	5.17e-290	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
PFPHHAOO_01364	1.67e-179	-	-	-	V	-	-	-	Beta-lactamase enzyme family
PFPHHAOO_01365	0.0	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Sucrose glucosyltransferase
PFPHHAOO_01366	6.33e-275	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
PFPHHAOO_01367	0.0	arcT	-	-	E	-	-	-	Dipeptidase
PFPHHAOO_01368	0.0	arcD	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
PFPHHAOO_01369	1.56e-229	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
PFPHHAOO_01370	3.23e-213	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
PFPHHAOO_01371	1.45e-171	-	-	-	I	-	-	-	alpha/beta hydrolase fold
PFPHHAOO_01372	4.8e-229	-	-	-	S	-	-	-	Conserved hypothetical protein 698
PFPHHAOO_01373	1.76e-122	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
PFPHHAOO_01374	1.26e-214	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
PFPHHAOO_01375	2.69e-228	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
PFPHHAOO_01376	2.57e-291	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
PFPHHAOO_01377	1.12e-112	-	-	-	Q	-	-	-	Methyltransferase
PFPHHAOO_01378	2.68e-150	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
PFPHHAOO_01379	9.61e-305	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
PFPHHAOO_01380	0.0	mycA	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
PFPHHAOO_01381	1.33e-179	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
PFPHHAOO_01382	2.52e-286	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
PFPHHAOO_01383	3.37e-308	-	-	-	M	-	-	-	Glycosyl transferase
PFPHHAOO_01385	8.27e-191	-	-	-	-	-	-	-	-
PFPHHAOO_01386	6.09e-162	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
PFPHHAOO_01387	5.22e-176	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PFPHHAOO_01388	2.7e-199	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
PFPHHAOO_01389	4.58e-194	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
PFPHHAOO_01390	1.64e-203	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
PFPHHAOO_01391	4.65e-167	-	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C-terminal domain protein
PFPHHAOO_01393	2.17e-243	-	-	-	-	-	-	-	-
PFPHHAOO_01394	2.32e-126	-	-	-	K	-	-	-	acetyltransferase
PFPHHAOO_01395	1.03e-106	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
PFPHHAOO_01396	1.71e-89	-	1.1.1.90	-	C	ko:K00055	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Zn-dependent alcohol dehydrogenases, class III
PFPHHAOO_01397	2.74e-80	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PFPHHAOO_01398	1.07e-239	-	-	-	-	-	-	-	-
PFPHHAOO_01399	4.8e-128	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PFPHHAOO_01400	1.54e-234	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
PFPHHAOO_01401	9.36e-36	-	-	-	NU	-	-	-	Mycoplasma protein of unknown function, DUF285
PFPHHAOO_01403	1.84e-203	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
PFPHHAOO_01404	9.38e-115	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
PFPHHAOO_01405	1.75e-158	-	-	-	O	-	-	-	Zinc-dependent metalloprotease
PFPHHAOO_01406	3.37e-71	-	-	-	L	-	-	-	Helix-turn-helix domain
PFPHHAOO_01410	1.1e-205	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
PFPHHAOO_01411	1.64e-204	-	-	-	S	-	-	-	EDD domain protein, DegV family
PFPHHAOO_01412	2.28e-118	-	-	-	-	-	-	-	-
PFPHHAOO_01413	2.4e-151	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
PFPHHAOO_01414	4.69e-199	gspA	-	-	M	-	-	-	family 8
PFPHHAOO_01415	5.06e-198	-	-	-	S	-	-	-	Alpha beta hydrolase
PFPHHAOO_01416	7.5e-122	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
PFPHHAOO_01417	4.27e-308	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
PFPHHAOO_01418	1.02e-51	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
PFPHHAOO_01419	2.76e-214	yvgN	-	-	C	-	-	-	Aldo keto reductase
PFPHHAOO_01420	1.63e-118	exuR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding protein domain
PFPHHAOO_01421	4.89e-279	-	-	-	G	ko:K03292	-	ko00000	MFS/sugar transport protein
PFPHHAOO_01422	3.41e-290	uxaC	5.3.1.12	-	G	ko:K01812	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	glucuronate isomerase
PFPHHAOO_01423	3.08e-120	-	-	-	S	-	-	-	module of peptide synthetase
PFPHHAOO_01425	6.44e-186	uxaB	1.1.1.58	-	G	ko:K00041	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	tagaturonate reductase activity
PFPHHAOO_01426	3.74e-152	uxaA	4.2.1.7	-	G	ko:K01685	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Altronate
PFPHHAOO_01427	9.05e-112	yqhA	-	-	G	-	-	-	Aldose 1-epimerase
PFPHHAOO_01428	4.55e-89	eda	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	KDPG and KHG aldolase
PFPHHAOO_01429	2.08e-208	uxaA	4.2.1.7	-	G	ko:K01685	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Altronate
PFPHHAOO_01430	1.05e-157	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	pfkB family carbohydrate kinase
PFPHHAOO_01431	1.52e-67	kdgR	-	-	K	-	-	-	FCD domain
PFPHHAOO_01432	4.07e-262	uxuB	1.1.1.57	-	G	ko:K00040	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Mannitol dehydrogenase C-terminal domain
PFPHHAOO_01433	6.75e-230	uxuA	4.2.1.8	-	G	ko:K01686	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of D-mannonate
PFPHHAOO_01434	6.81e-275	uxuT	-	-	G	ko:K03292,ko:K16210	-	ko00000,ko02000	MFS/sugar transport protein
PFPHHAOO_01435	5.71e-276	uxaC	5.3.1.12	-	G	ko:K01812	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	glucuronate isomerase
PFPHHAOO_01436	3.95e-19	-	-	-	K	ko:K21498	-	ko00000,ko02048	Helix-turn-helix XRE-family like proteins
PFPHHAOO_01437	4.49e-21	-	-	-	K	ko:K21498	-	ko00000,ko02048	Helix-turn-helix XRE-family like proteins
PFPHHAOO_01438	2.95e-49	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
PFPHHAOO_01439	3.14e-174	kduI	5.3.1.17	-	G	ko:K01815	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
PFPHHAOO_01440	2.77e-165	kduD	1.1.1.127	-	IQ	ko:K00065	ko00040,map00040	ko00000,ko00001,ko01000	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PFPHHAOO_01441	9.51e-88	-	-	-	K	-	-	-	Bacterial transcriptional regulator
PFPHHAOO_01442	3.19e-187	rlrB	-	-	K	-	-	-	LysR substrate binding domain protein
PFPHHAOO_01443	3.85e-66	-	-	-	C	-	-	-	Flavodoxin
PFPHHAOO_01444	9.06e-99	-	-	-	S	-	-	-	Cupin domain
PFPHHAOO_01445	2.93e-92	-	-	-	S	-	-	-	UPF0756 membrane protein
PFPHHAOO_01446	3.5e-294	-	-	-	U	-	-	-	Belongs to the major facilitator superfamily
PFPHHAOO_01447	3.97e-97	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
PFPHHAOO_01448	2.2e-315	yhdP	-	-	S	-	-	-	Transporter associated domain
PFPHHAOO_01449	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	ABC1 family
PFPHHAOO_01450	5.2e-186	-	-	-	S	-	-	-	DUF218 domain
PFPHHAOO_01451	1.96e-89	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PFPHHAOO_01452	4.18e-75	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PFPHHAOO_01453	1.73e-70	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PFPHHAOO_01454	0.0	uvrA2	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC, A subunit
PFPHHAOO_01463	1.12e-167	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
PFPHHAOO_01464	1.04e-174	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
PFPHHAOO_01465	1.19e-183	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PFPHHAOO_01466	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
PFPHHAOO_01467	2.29e-97	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
PFPHHAOO_01468	4.19e-96	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
PFPHHAOO_01469	7.83e-283	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
PFPHHAOO_01470	5.12e-159	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
PFPHHAOO_01471	2.72e-194	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
PFPHHAOO_01472	1.99e-44	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PFPHHAOO_01473	3.58e-215	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PFPHHAOO_01474	1.94e-100	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
PFPHHAOO_01475	1.39e-91	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
PFPHHAOO_01477	3.42e-258	xerS	-	-	L	-	-	-	Belongs to the 'phage' integrase family
PFPHHAOO_01478	4.34e-19	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	Levansucrase/Invertase
PFPHHAOO_01479	2.46e-202	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	Levansucrase/Invertase
PFPHHAOO_01480	2.53e-74	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	Levansucrase/Invertase
PFPHHAOO_01481	1.15e-200	rssA	-	-	S	-	-	-	Phospholipase, patatin family
PFPHHAOO_01482	9.45e-152	-	-	-	L	-	-	-	Integrase
PFPHHAOO_01483	2.46e-126	-	-	-	EG	-	-	-	EamA-like transporter family
PFPHHAOO_01484	5.14e-92	-	-	-	L	-	-	-	Helix-turn-helix domain
PFPHHAOO_01485	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
PFPHHAOO_01486	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
PFPHHAOO_01487	5.29e-263	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
PFPHHAOO_01488	3.24e-221	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
PFPHHAOO_01489	1.26e-96	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PFPHHAOO_01490	7.39e-85	esbA	-	-	S	-	-	-	Family of unknown function (DUF5322)
PFPHHAOO_01491	1.55e-91	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
PFPHHAOO_01492	1.7e-282	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
PFPHHAOO_01493	6.59e-106	-	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
PFPHHAOO_01494	3.25e-72	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
PFPHHAOO_01495	5.6e-129	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
PFPHHAOO_01496	2.01e-152	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
PFPHHAOO_01497	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
PFPHHAOO_01498	2.32e-206	-	-	-	EG	-	-	-	EamA-like transporter family
PFPHHAOO_01499	7.96e-158	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
PFPHHAOO_01500	1.57e-113	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
PFPHHAOO_01501	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
PFPHHAOO_01502	2.86e-217	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
PFPHHAOO_01503	8.5e-218	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
PFPHHAOO_01504	1.13e-271	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
PFPHHAOO_01505	3.63e-247	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
PFPHHAOO_01506	1.13e-117	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
PFPHHAOO_01507	0.0	-	-	-	L	-	-	-	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
PFPHHAOO_01508	0.0	-	-	-	L	-	-	-	Transposase
PFPHHAOO_01509	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
PFPHHAOO_01510	7.8e-238	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding protein-like domain
PFPHHAOO_01511	7.04e-215	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
PFPHHAOO_01512	4.96e-222	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
PFPHHAOO_01513	7.5e-56	lytS	2.7.13.3	-	T	ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	LytS YhcK-type transmembrane receptor domain protein
PFPHHAOO_01514	1.8e-190	-	-	-	O	-	-	-	Band 7 protein
PFPHHAOO_01515	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
PFPHHAOO_01516	3.3e-198	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
PFPHHAOO_01517	1.43e-51	-	-	-	S	-	-	-	Cytochrome B5
PFPHHAOO_01518	1.18e-146	nreC	-	-	K	ko:K07696	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	PFAM regulatory protein LuxR
PFPHHAOO_01519	6.4e-204	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
PFPHHAOO_01520	1.18e-76	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
PFPHHAOO_01521	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
PFPHHAOO_01522	1.24e-103	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
PFPHHAOO_01523	8.34e-295	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PFPHHAOO_01524	2.36e-305	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
PFPHHAOO_01525	1.56e-184	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
PFPHHAOO_01526	6.71e-41	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain
PFPHHAOO_01527	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
PFPHHAOO_01528	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
PFPHHAOO_01529	1.16e-199	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
PFPHHAOO_01530	2.08e-79	yuxO	-	-	Q	-	-	-	Thioesterase superfamily
PFPHHAOO_01531	1.87e-137	yvrI	-	-	K	ko:K03091,ko:K03093	-	ko00000,ko03021	sigma factor activity
PFPHHAOO_01532	8.99e-258	-	-	-	G	-	-	-	Transporter, major facilitator family protein
PFPHHAOO_01533	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
PFPHHAOO_01534	1.87e-65	-	-	-	T	ko:K10716	-	ko00000,ko02000	Ion transport 2 domain protein
PFPHHAOO_01535	4.52e-101	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
PFPHHAOO_01536	1.86e-286	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
PFPHHAOO_01537	1.96e-123	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
PFPHHAOO_01538	4.62e-232	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PFPHHAOO_01539	3.68e-228	rihA	-	-	F	ko:K01250	-	ko00000,ko01000	Inosine-uridine preferring nucleoside hydrolase
PFPHHAOO_01541	0.0	-	-	-	L	-	-	-	PLD-like domain
PFPHHAOO_01542	8.36e-69	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	type I restriction modification DNA specificity domain protein
PFPHHAOO_01543	1.02e-228	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
PFPHHAOO_01544	3.08e-93	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
PFPHHAOO_01545	1.01e-247	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
PFPHHAOO_01546	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
PFPHHAOO_01547	3.09e-19	-	-	-	IQ	-	-	-	KR domain
PFPHHAOO_01548	3.04e-56	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
PFPHHAOO_01549	7.29e-60	-	-	-	-	-	-	-	-
PFPHHAOO_01550	1.81e-41	-	-	-	-	-	-	-	-
PFPHHAOO_01551	3.8e-63	-	-	-	-	-	-	-	-
PFPHHAOO_01552	5.09e-302	-	-	-	L	-	-	-	Transposase
PFPHHAOO_01553	1.34e-174	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
PFPHHAOO_01554	0.0	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
PFPHHAOO_01555	1e-47	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PFPHHAOO_01556	1.29e-299	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
PFPHHAOO_01557	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PFPHHAOO_01558	4.54e-09	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
PFPHHAOO_01559	1.55e-79	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
PFPHHAOO_01560	4.93e-266	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PFPHHAOO_01561	5.31e-82	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
PFPHHAOO_01562	0.0	-	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
PFPHHAOO_01563	9.21e-308	codA	3.5.4.1	-	F	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000	cytosine deaminase
PFPHHAOO_01564	8.04e-186	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
PFPHHAOO_01565	3.29e-146	-	-	-	S	-	-	-	(CBS) domain
PFPHHAOO_01566	1.13e-131	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
PFPHHAOO_01567	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PFPHHAOO_01568	1.01e-52	yabO	-	-	J	-	-	-	S4 domain protein
PFPHHAOO_01569	1.02e-74	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
PFPHHAOO_01570	5.75e-103	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
PFPHHAOO_01571	0.0	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
PFPHHAOO_01572	8.67e-124	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
PFPHHAOO_01573	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PFPHHAOO_01574	1.87e-217	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
PFPHHAOO_01575	6.21e-241	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PFPHHAOO_01576	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
PFPHHAOO_01578	5.09e-302	-	-	-	L	-	-	-	Transposase
PFPHHAOO_01579	0.0	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
PFPHHAOO_01580	1.69e-177	-	-	-	T	-	-	-	EAL domain
PFPHHAOO_01581	2.72e-164	-	-	-	F	-	-	-	glutamine amidotransferase
PFPHHAOO_01582	6.31e-79	-	-	-	-	-	-	-	-
PFPHHAOO_01583	4.71e-128	qorB	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NmrA-like family
PFPHHAOO_01584	1.15e-204	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
PFPHHAOO_01585	4.24e-190	-	-	-	K	-	-	-	Transcriptional regulator
PFPHHAOO_01586	1.99e-235	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase, type I
PFPHHAOO_01587	1.45e-214	ypuA	-	-	S	-	-	-	Protein of unknown function (DUF1002)
PFPHHAOO_01588	1.67e-291	aadAT	-	-	EK	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000	Aminotransferase, class I
PFPHHAOO_01589	4.61e-223	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
PFPHHAOO_01590	1.2e-195	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
PFPHHAOO_01591	3.74e-67	-	-	-	S	-	-	-	Alpha beta hydrolase
PFPHHAOO_01592	1.27e-115	-	-	-	J	ko:K19055	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
PFPHHAOO_01593	1.58e-91	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PFPHHAOO_01594	5.79e-247	flp	-	-	V	-	-	-	Beta-lactamase
PFPHHAOO_01595	1.02e-121	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
PFPHHAOO_01596	1.09e-127	-	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
PFPHHAOO_01597	6.65e-136	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
PFPHHAOO_01598	0.0	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
PFPHHAOO_01599	2.57e-141	-	-	-	S	-	-	-	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
PFPHHAOO_01600	1.58e-66	azlD	-	-	E	-	-	-	Branched-chain amino acid transport
PFPHHAOO_01601	4.42e-153	azlC	-	-	E	-	-	-	azaleucine resistance protein AzlC
PFPHHAOO_01602	0.0	-	-	-	K	-	-	-	Aminotransferase class I and II
PFPHHAOO_01603	1.52e-239	-	-	-	S	-	-	-	amidohydrolase
PFPHHAOO_01604	5.95e-134	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
PFPHHAOO_01605	1.73e-48	-	-	-	L	-	-	-	PFAM Integrase catalytic region
PFPHHAOO_01607	2.45e-63	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase, GNAT family
PFPHHAOO_01608	5.59e-20	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase, GNAT family
PFPHHAOO_01609	1.41e-146	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
PFPHHAOO_01610	2.61e-315	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
PFPHHAOO_01611	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PFPHHAOO_01612	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
PFPHHAOO_01613	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
PFPHHAOO_01614	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PFPHHAOO_01615	1.08e-170	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
PFPHHAOO_01616	1.21e-171	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PFPHHAOO_01617	1.39e-76	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
PFPHHAOO_01618	7.96e-21	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
PFPHHAOO_01619	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PFPHHAOO_01620	4.03e-263	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
PFPHHAOO_01621	2.21e-46	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
PFPHHAOO_01622	1.63e-259	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PFPHHAOO_01623	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PFPHHAOO_01624	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PFPHHAOO_01625	4.55e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
PFPHHAOO_01626	1.34e-110	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
PFPHHAOO_01627	9.36e-48	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PFPHHAOO_01628	1.31e-97	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
PFPHHAOO_01629	1.67e-23	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	sugar-binding domain protein
PFPHHAOO_01630	1.14e-66	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	sugar-binding domain protein
PFPHHAOO_01631	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
PFPHHAOO_01632	1.25e-97	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
PFPHHAOO_01633	7.36e-308	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
PFPHHAOO_01634	7.59e-269	yttB	-	-	EGP	-	-	-	Major Facilitator
PFPHHAOO_01635	7.71e-81	-	-	-	-	-	-	-	-
PFPHHAOO_01636	1.46e-207	-	-	-	S	-	-	-	Polyphosphate nucleotide phosphotransferase, PPK2 family
PFPHHAOO_01637	8.32e-47	-	-	-	S	-	-	-	Fic/DOC family
PFPHHAOO_01638	2.09e-90	-	-	-	S	-	-	-	Fic/DOC family
PFPHHAOO_01640	6.3e-95	-	-	-	K	ko:K18909	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
PFPHHAOO_01641	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
PFPHHAOO_01643	1.29e-168	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
PFPHHAOO_01644	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
PFPHHAOO_01645	1.09e-311	yycH	-	-	S	-	-	-	YycH protein
PFPHHAOO_01646	1.18e-191	yycI	-	-	S	-	-	-	YycH protein
PFPHHAOO_01647	2.52e-196	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
PFPHHAOO_01648	7.23e-284	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
PFPHHAOO_01649	9.62e-116	pgpA	-	-	I	-	-	-	Phosphatidylglycerophosphatase A
PFPHHAOO_01650	4.26e-225	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
PFPHHAOO_01651	2.63e-115	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PFPHHAOO_01653	1.56e-125	-	-	-	S	-	-	-	reductase
PFPHHAOO_01654	1.08e-288	dhaT	1.1.1.202	-	C	ko:K00086	ko00561,ko00640,map00561,map00640	ko00000,ko00001,ko01000	Dehydrogenase
PFPHHAOO_01655	1.7e-199	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
PFPHHAOO_01656	1.52e-192	-	-	-	E	-	-	-	Glyoxalase-like domain
PFPHHAOO_01657	3.54e-188	-	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PFPHHAOO_01658	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
PFPHHAOO_01659	3.2e-197	hlyD3	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PFPHHAOO_01660	3.99e-166	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
PFPHHAOO_01661	7.58e-270	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
PFPHHAOO_01662	1.28e-70	-	-	-	-	-	-	-	-
PFPHHAOO_01663	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
PFPHHAOO_01666	3.99e-68	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
PFPHHAOO_01667	1.79e-111	-	-	-	K	-	-	-	FR47-like protein
PFPHHAOO_01668	2.79e-97	-	-	-	O	-	-	-	OsmC-like protein
PFPHHAOO_01669	3.47e-221	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PFPHHAOO_01670	1.13e-272	-	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
PFPHHAOO_01671	2.49e-43	-	-	-	-	-	-	-	-
PFPHHAOO_01672	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	associated with various cellular activities
PFPHHAOO_01674	1.12e-135	-	-	-	K	-	-	-	PFAM GCN5-related N-acetyltransferase
PFPHHAOO_01675	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PFPHHAOO_01676	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
PFPHHAOO_01677	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
PFPHHAOO_01678	5.18e-222	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
PFPHHAOO_01679	2.2e-273	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
PFPHHAOO_01680	0.0	malT	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
PFPHHAOO_01681	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
PFPHHAOO_01682	2.05e-153	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
PFPHHAOO_01683	8.84e-94	-	-	-	-	-	-	-	-
PFPHHAOO_01684	1.24e-112	-	-	-	T	-	-	-	Region found in RelA / SpoT proteins
PFPHHAOO_01685	3.15e-153	dltr	-	-	K	-	-	-	response regulator
PFPHHAOO_01686	3.23e-289	sptS	-	-	T	-	-	-	Histidine kinase
PFPHHAOO_01687	1.38e-272	-	-	-	P	-	-	-	Voltage gated chloride channel
PFPHHAOO_01688	0.0	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
PFPHHAOO_01689	2.5e-174	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
PFPHHAOO_01690	1.48e-214	-	-	-	C	-	-	-	Aldo keto reductase
PFPHHAOO_01691	0.0	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
PFPHHAOO_01692	6.51e-114	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
PFPHHAOO_01693	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
PFPHHAOO_01694	2.95e-239	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
PFPHHAOO_01695	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PFPHHAOO_01696	2.55e-121	-	-	-	-	-	-	-	-
PFPHHAOO_01697	4.65e-123	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PFPHHAOO_01699	8.95e-18	-	-	-	E	-	-	-	amino acid
PFPHHAOO_01700	2.53e-17	-	-	-	K	-	-	-	Transcriptional regulator, TetR family
PFPHHAOO_01701	1.13e-96	-	-	-	K	-	-	-	Transcriptional regulator, TetR family
PFPHHAOO_01702	8.53e-95	-	-	-	-	-	-	-	-
PFPHHAOO_01703	0.0	tagE6	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
PFPHHAOO_01704	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Poly(Glycerol-phosphate) alpha-glucosyltransferase
PFPHHAOO_01705	0.0	sdrF	-	-	M	ko:K14194	ko05150,map05150	ko00000,ko00001	protein which possibly mediates interactions of S.aureus with components of the extracellular matrix of higher eukaryotes
PFPHHAOO_01706	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
PFPHHAOO_01707	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
PFPHHAOO_01708	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
PFPHHAOO_01709	8.13e-263	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
PFPHHAOO_01710	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
PFPHHAOO_01711	8.55e-226	cytR	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	Transcriptional regulator, LacI family
PFPHHAOO_01712	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PFPHHAOO_01713	5.75e-130	-	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
PFPHHAOO_01714	6.57e-262	-	1.5.1.36	-	S	ko:K19784,ko:K22393,ko:K22394	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
PFPHHAOO_01715	9.36e-224	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
PFPHHAOO_01717	0.000106	-	3.1.3.48	-	D	ko:K01104	-	ko00000,ko01000	nuclear chromosome segregation
PFPHHAOO_01718	1.15e-226	-	-	-	S	-	-	-	FRG
PFPHHAOO_01719	3.41e-267	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
PFPHHAOO_01720	5.25e-110	panE1	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PFPHHAOO_01721	5.33e-103	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
PFPHHAOO_01722	2.87e-88	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
PFPHHAOO_01723	3.67e-153	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
PFPHHAOO_01724	1.09e-251	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
PFPHHAOO_01725	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
PFPHHAOO_01726	3.29e-146	yjbH	-	-	Q	-	-	-	Thioredoxin
PFPHHAOO_01727	7.45e-150	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
PFPHHAOO_01728	1.2e-195	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PFPHHAOO_01729	9.29e-220	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
PFPHHAOO_01730	1.58e-22	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
PFPHHAOO_01733	1.02e-139	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
PFPHHAOO_01734	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
PFPHHAOO_01735	4.08e-147	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
PFPHHAOO_01736	3.01e-125	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PFPHHAOO_01737	1.25e-262	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
PFPHHAOO_01738	1.01e-186	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PFPHHAOO_01739	7.65e-184	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PFPHHAOO_01740	2.33e-264	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PFPHHAOO_01741	4.88e-42	-	-	-	-	-	-	-	-
PFPHHAOO_01742	5.07e-82	-	-	-	-	-	-	-	-
PFPHHAOO_01743	4.81e-22	-	-	-	-	-	-	-	-
PFPHHAOO_01744	8e-39	-	-	-	-	-	-	-	-
PFPHHAOO_01745	1.08e-31	-	-	-	L	-	-	-	Integrase
PFPHHAOO_01746	2.7e-18	XK27_09155	-	-	K	-	-	-	Transcriptional
PFPHHAOO_01747	2.79e-130	cadD	-	-	P	-	-	-	Cadmium resistance transporter
PFPHHAOO_01748	2.07e-73	cadX	-	-	K	ko:K21903	-	ko00000,ko03000	Bacterial regulatory protein, arsR family
PFPHHAOO_01749	1.31e-93	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PFPHHAOO_01750	2.52e-232	arsB	-	-	P	ko:K03325	-	ko00000,ko02000	Sodium Bile acid symporter family
PFPHHAOO_01751	1.73e-56	arsR	-	-	K	ko:K03892	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
PFPHHAOO_01752	1.47e-81	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PFPHHAOO_01753	2.92e-57	arsB	-	-	P	ko:K03325	-	ko00000,ko02000	Sodium Bile acid symporter family
PFPHHAOO_01754	4.15e-23	-	-	-	K	-	-	-	Helix-turn-helix domain
PFPHHAOO_01755	2.27e-24	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
PFPHHAOO_01756	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
PFPHHAOO_01757	2.81e-184	-	-	-	S	-	-	-	Putative ABC-transporter type IV
PFPHHAOO_01758	2.85e-135	-	-	-	NU	-	-	-	mannosyl-glycoprotein
PFPHHAOO_01759	5.41e-316	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
PFPHHAOO_01760	8.26e-290	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
PFPHHAOO_01761	4.53e-263	yngD	-	-	S	ko:K07097	-	ko00000	DHHA1 domain
PFPHHAOO_01762	1.43e-41	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
PFPHHAOO_01764	1.58e-70	-	-	-	-	-	-	-	-
PFPHHAOO_01765	5.83e-152	yrkL	-	-	S	-	-	-	Flavodoxin-like fold
PFPHHAOO_01767	2.01e-84	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
PFPHHAOO_01768	3.32e-154	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
PFPHHAOO_01769	1.02e-261	-	-	-	S	-	-	-	associated with various cellular activities
PFPHHAOO_01770	9.52e-301	-	-	-	S	-	-	-	Putative metallopeptidase domain
PFPHHAOO_01771	8.55e-64	-	-	-	-	-	-	-	-
PFPHHAOO_01772	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
PFPHHAOO_01773	9.1e-139	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
PFPHHAOO_01774	8.54e-113	ymdB	-	-	S	-	-	-	Macro domain protein
PFPHHAOO_01775	4.05e-250	-	-	-	EGP	-	-	-	Major Facilitator
PFPHHAOO_01776	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PFPHHAOO_01777	7.86e-13	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
PFPHHAOO_01778	8.81e-212	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
PFPHHAOO_01779	3.87e-199	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
PFPHHAOO_01780	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
PFPHHAOO_01781	1.67e-172	XK27_05695	-	-	V	ko:K02003,ko:K19083	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
PFPHHAOO_01782	1.39e-229	kinG	-	-	T	-	-	-	Histidine kinase-like ATPases
PFPHHAOO_01783	1.06e-161	XK27_10500	-	-	K	-	-	-	response regulator
PFPHHAOO_01784	8.44e-201	yvgN	-	-	S	-	-	-	Aldo keto reductase
PFPHHAOO_01785	3.13e-172	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
PFPHHAOO_01786	1.59e-105	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PFPHHAOO_01787	3.04e-259	-	-	-	-	-	-	-	-
PFPHHAOO_01788	1.76e-68	-	-	-	-	-	-	-	-
PFPHHAOO_01789	1.21e-48	-	-	-	-	-	-	-	-
PFPHHAOO_01790	9.57e-47	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
PFPHHAOO_01791	1.15e-17	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
PFPHHAOO_01792	1.06e-184	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
PFPHHAOO_01793	4.27e-224	celE3	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
PFPHHAOO_01794	4.92e-286	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
PFPHHAOO_01795	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
PFPHHAOO_01796	9.37e-230	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
PFPHHAOO_01806	5.19e-127	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
PFPHHAOO_01807	1.66e-305	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
PFPHHAOO_01808	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
PFPHHAOO_01809	4.6e-143	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PFPHHAOO_01810	1.76e-201	-	-	-	O	-	-	-	Uncharacterized protein family (UPF0051)
PFPHHAOO_01811	5.35e-86	-	-	-	M	-	-	-	LysM domain protein
PFPHHAOO_01812	0.0	-	-	-	EP	-	-	-	Psort location Cytoplasmic, score
PFPHHAOO_01813	8.05e-132	-	-	-	M	-	-	-	LysM domain protein
PFPHHAOO_01814	2.23e-187	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
PFPHHAOO_01815	6.91e-299	-	1.3.1.1	-	E	ko:K17722	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
PFPHHAOO_01816	1.32e-308	-	1.3.1.1	-	C	ko:K17723	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
PFPHHAOO_01817	1.23e-194	yeaE	-	-	S	-	-	-	Aldo keto
PFPHHAOO_01818	3.81e-100	hsp	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
PFPHHAOO_01819	0.0	umuC	-	-	L	ko:K03502	-	ko00000,ko03400	impB/mucB/samB family C-terminal domain
PFPHHAOO_01820	4.4e-101	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
PFPHHAOO_01821	1e-101	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
PFPHHAOO_01822	1.06e-148	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
PFPHHAOO_01823	6.92e-130	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
PFPHHAOO_01824	4.76e-170	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
PFPHHAOO_01825	2.66e-120	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
PFPHHAOO_01826	1.21e-143	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
PFPHHAOO_01827	4.36e-283	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PFPHHAOO_01828	6.64e-182	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
PFPHHAOO_01830	3.12e-90	-	-	-	-	ko:K02248	-	ko00000,ko00002,ko02044	-
PFPHHAOO_01831	1.96e-55	-	-	-	-	-	-	-	-
PFPHHAOO_01832	2.12e-102	-	-	-	NU	ko:K02246	-	ko00000,ko00002,ko02044	general secretion pathway protein
PFPHHAOO_01833	6.31e-62	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
PFPHHAOO_01834	6.11e-233	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
PFPHHAOO_01835	1.56e-230	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
PFPHHAOO_01836	7.07e-168	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
PFPHHAOO_01837	1.05e-174	-	-	-	-	-	-	-	-
PFPHHAOO_01838	7.72e-232	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
PFPHHAOO_01839	4.92e-266	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
PFPHHAOO_01840	2.9e-72	-	-	-	-	-	-	-	-
PFPHHAOO_01841	8.88e-71	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
PFPHHAOO_01842	7.58e-189	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
PFPHHAOO_01843	3.3e-197	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
PFPHHAOO_01844	8.55e-99	ykuL	-	-	S	-	-	-	(CBS) domain
PFPHHAOO_01845	1.65e-120	-	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
PFPHHAOO_01846	2.44e-135	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PFPHHAOO_01847	1.62e-187	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
PFPHHAOO_01848	5.82e-124	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
PFPHHAOO_01849	2.86e-72	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
PFPHHAOO_01850	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
PFPHHAOO_01851	1.44e-121	cvpA	-	-	S	-	-	-	Colicin V production protein
PFPHHAOO_01852	3.75e-63	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
PFPHHAOO_01853	3.62e-100	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PFPHHAOO_01854	8.03e-58	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
PFPHHAOO_01855	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PFPHHAOO_01856	0.0	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
PFPHHAOO_01857	3.56e-233	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
PFPHHAOO_01858	1.44e-59	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
PFPHHAOO_01859	9.79e-239	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
PFPHHAOO_01860	2.74e-242	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
PFPHHAOO_01861	4.34e-131	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
PFPHHAOO_01862	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PFPHHAOO_01863	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PFPHHAOO_01864	2.29e-276	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
PFPHHAOO_01865	6.3e-251	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PFPHHAOO_01866	6.52e-289	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
PFPHHAOO_01867	1.16e-133	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PFPHHAOO_01868	1.71e-189	-	-	-	S	-	-	-	Helix-turn-helix domain
PFPHHAOO_01869	8.66e-316	ymfH	-	-	S	-	-	-	Peptidase M16
PFPHHAOO_01870	1.87e-288	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
PFPHHAOO_01871	3.32e-204	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
PFPHHAOO_01872	1.45e-151	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
PFPHHAOO_01873	4.45e-141	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
PFPHHAOO_01874	1.69e-120	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
PFPHHAOO_01875	3.82e-195	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
PFPHHAOO_01876	8.33e-230	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
PFPHHAOO_01877	4.2e-157	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
PFPHHAOO_01878	2.66e-306	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
PFPHHAOO_01879	1.81e-294	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
PFPHHAOO_01880	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
PFPHHAOO_01881	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
PFPHHAOO_01882	5.45e-233	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
PFPHHAOO_01883	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
PFPHHAOO_01884	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
PFPHHAOO_01885	2.37e-291	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PFPHHAOO_01886	7.1e-274	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
PFPHHAOO_01887	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
PFPHHAOO_01888	5.96e-139	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PFPHHAOO_01889	9.51e-95	-	-	-	L	-	-	-	PFAM Integrase catalytic region
PFPHHAOO_01890	2.1e-59	-	-	-	L	-	-	-	Reverse transcriptase (RNA-dependent DNA polymerase)
PFPHHAOO_01892	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
PFPHHAOO_01893	1.5e-226	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
PFPHHAOO_01894	0.0	atp2C1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
PFPHHAOO_01895	1.19e-111	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
PFPHHAOO_01896	1.56e-222	yagE	-	-	E	-	-	-	amino acid
PFPHHAOO_01897	2.14e-148	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant
PFPHHAOO_01898	7.54e-122	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
PFPHHAOO_01899	1.69e-44	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
PFPHHAOO_01900	4.85e-233	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
PFPHHAOO_01901	5.46e-233	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
PFPHHAOO_01913	6.73e-51	-	-	-	S	-	-	-	Cytochrome B5
PFPHHAOO_01914	2.69e-79	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
PFPHHAOO_01915	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
PFPHHAOO_01916	7.01e-244	-	-	-	E	-	-	-	Zinc-binding dehydrogenase
PFPHHAOO_01917	1.46e-110	-	-	-	K	-	-	-	transcriptional regulator (TetR family)
PFPHHAOO_01918	7.46e-222	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
PFPHHAOO_01919	2.37e-152	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PFPHHAOO_01920	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PFPHHAOO_01921	1.61e-48	-	-	-	-	-	-	-	-
PFPHHAOO_01922	3.35e-65	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
PFPHHAOO_01923	0.0	-	3.2.1.17	CBM50	NU	ko:K01185,ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
PFPHHAOO_01924	6.94e-59	p75	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
PFPHHAOO_01925	2.94e-193	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
PFPHHAOO_01933	4.87e-07	-	-	-	K	ko:K07726	-	ko00000,ko03000	sequence-specific DNA binding
PFPHHAOO_01934	1.43e-34	-	-	-	S	-	-	-	RelE toxin of RelE / RelB toxin-antitoxin system
PFPHHAOO_01936	1.83e-121	-	-	-	L	-	-	-	Integrase
PFPHHAOO_01937	6.88e-49	-	-	-	-	-	-	-	-
PFPHHAOO_01938	8.51e-95	XK27_02070	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
PFPHHAOO_01939	3.72e-251	-	-	-	-	-	-	-	-
PFPHHAOO_01940	8.27e-213	qor	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
PFPHHAOO_01941	9.94e-55	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
PFPHHAOO_01942	2.71e-155	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
PFPHHAOO_01943	5.58e-88	-	-	-	L	-	-	-	Helix-turn-helix domain
PFPHHAOO_01945	5.76e-111	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
PFPHHAOO_01946	1.93e-147	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
PFPHHAOO_01947	3.7e-47	-	-	-	-	-	-	-	-
PFPHHAOO_01948	9.37e-22	-	-	-	-	-	-	-	-
PFPHHAOO_01949	7.17e-111	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
PFPHHAOO_01950	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
PFPHHAOO_01951	8.37e-145	-	-	-	GM	-	-	-	NAD dependent epimerase dehydratase family protein
PFPHHAOO_01952	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
PFPHHAOO_01953	2.65e-269	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
PFPHHAOO_01954	9.71e-293	-	-	-	-	-	-	-	-
PFPHHAOO_01955	7.27e-106	-	-	-	K	-	-	-	Transcriptional regulator, HxlR family
PFPHHAOO_01956	7.53e-137	XK27_02070	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
PFPHHAOO_01957	1.07e-66	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
PFPHHAOO_01958	1.11e-156	-	-	-	GM	-	-	-	NmrA-like family
PFPHHAOO_01959	4.97e-97	-	-	-	S	ko:K02348	-	ko00000	Gnat family
PFPHHAOO_01960	3.78e-20	-	-	-	S	-	-	-	Cytochrome B5
PFPHHAOO_01961	8.37e-280	-	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
PFPHHAOO_01963	8.95e-20	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PFPHHAOO_01964	9.04e-152	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PFPHHAOO_01965	4.67e-313	-	-	-	E	ko:K03294	-	ko00000	amino acid
PFPHHAOO_01966	2.71e-39	npp	-	-	S	-	-	-	type I phosphodiesterase nucleotide pyrophosphatase
PFPHHAOO_01967	1.37e-83	npp	-	-	S	-	-	-	type I phosphodiesterase nucleotide pyrophosphatase
PFPHHAOO_01968	3.08e-77	npp	-	-	S	-	-	-	type I phosphodiesterase nucleotide pyrophosphatase
PFPHHAOO_01969	2.2e-69	npp	-	-	S	-	-	-	type I phosphodiesterase nucleotide pyrophosphatase
PFPHHAOO_01970	3.49e-106	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
PFPHHAOO_01971	9.44e-94	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
PFPHHAOO_01972	3.95e-07	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
PFPHHAOO_01974	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PFPHHAOO_01975	2.94e-72	-	-	-	-	-	-	-	-
PFPHHAOO_01976	9.75e-145	frnE	5.3.4.1	-	Q	ko:K01829	-	ko00000,ko01000	DSBA-like thioredoxin domain
PFPHHAOO_01977	1.24e-209	-	-	-	I	-	-	-	alpha/beta hydrolase fold
PFPHHAOO_01978	2.05e-27	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
PFPHHAOO_01979	4.22e-41	-	-	-	S	-	-	-	Phage derived protein Gp49-like (DUF891)
PFPHHAOO_01980	1.39e-257	-	-	-	M	-	-	-	hydrolase, family 25
PFPHHAOO_01981	3.67e-69	-	-	-	S	-	-	-	Bacteriophage holin of superfamily 6 (Holin_LLH)
PFPHHAOO_01982	3.41e-47	-	-	-	S	-	-	-	Bacteriophage holin family
PFPHHAOO_01986	7.94e-109	-	-	-	S	-	-	-	Domain of unknown function (DUF2479)
PFPHHAOO_01988	0.0	spoIIQ	-	-	M	ko:K06386	-	ko00000	Peptidase family M23
PFPHHAOO_01989	5.09e-202	-	-	-	S	-	-	-	Phage tail protein
PFPHHAOO_01990	0.0	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
PFPHHAOO_01991	8.23e-28	-	-	-	-	-	-	-	-
PFPHHAOO_01993	2.59e-137	-	-	-	-	-	-	-	-
PFPHHAOO_01994	1.34e-98	-	-	-	-	-	-	-	-
PFPHHAOO_01995	1.75e-60	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
PFPHHAOO_01996	4.51e-54	-	-	-	S	-	-	-	Phage head-tail joining protein
PFPHHAOO_01997	1.64e-89	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
PFPHHAOO_01998	4.12e-93	-	-	-	S	-	-	-	Phage capsid family
PFPHHAOO_01999	5.97e-156	-	-	-	S	-	-	-	Phage capsid family
PFPHHAOO_02000	3.54e-148	-	-	-	S	ko:K06904	-	ko00000	Caudovirus prohead serine protease
PFPHHAOO_02001	2.96e-303	-	-	-	S	-	-	-	Phage portal protein
PFPHHAOO_02004	0.0	terL	-	-	S	-	-	-	overlaps another CDS with the same product name
PFPHHAOO_02005	8.04e-101	-	-	-	L	-	-	-	Phage terminase, small subunit
PFPHHAOO_02006	1.44e-194	-	-	-	L	-	-	-	HNH nucleases
PFPHHAOO_02010	3.15e-108	-	-	-	S	-	-	-	Phage transcriptional regulator, ArpU family
PFPHHAOO_02012	8.94e-92	XK27_00160	-	-	S	-	-	-	Domain of unknown function (DUF5052)
PFPHHAOO_02016	7.57e-163	-	-	-	-	-	-	-	-
PFPHHAOO_02017	8.03e-92	-	-	-	-	-	-	-	-
PFPHHAOO_02019	2.18e-54	-	-	-	S	-	-	-	HNH endonuclease
PFPHHAOO_02022	3.03e-176	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
PFPHHAOO_02023	2.33e-112	-	-	-	V	-	-	-	site-specific DNA-methyltransferase (adenine-specific) activity
PFPHHAOO_02024	6.94e-176	-	-	-	L	-	-	-	DnaD domain protein
PFPHHAOO_02027	1.62e-26	-	-	-	-	-	-	-	-
PFPHHAOO_02028	3.87e-23	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
PFPHHAOO_02029	3.69e-32	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2188)
PFPHHAOO_02036	9.06e-15	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
PFPHHAOO_02037	9.75e-101	-	-	-	K	-	-	-	Peptidase S24-like
PFPHHAOO_02041	3.95e-29	-	-	-	-	-	-	-	-
PFPHHAOO_02043	4.15e-49	-	-	-	-	-	-	-	-
PFPHHAOO_02046	3.12e-90	-	-	-	S	-	-	-	Domain of unknown function (DUF4393)
PFPHHAOO_02048	1.64e-178	int2	-	-	L	-	-	-	Belongs to the 'phage' integrase family
PFPHHAOO_02050	1.37e-64	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
PFPHHAOO_02051	5.84e-194	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
PFPHHAOO_02052	1.38e-117	ntd	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside
PFPHHAOO_02053	1.15e-25	-	-	-	-	-	-	-	-
PFPHHAOO_02054	6.99e-208	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
PFPHHAOO_02055	5.93e-149	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
PFPHHAOO_02056	3.91e-95	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
PFPHHAOO_02057	8.32e-56	-	-	-	S	ko:K09790	-	ko00000	Protein of unknown function (DUF454)
PFPHHAOO_02058	0.0	-	-	-	I	-	-	-	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PFPHHAOO_02059	1.99e-201	endA	-	-	V	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
PFPHHAOO_02060	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
PFPHHAOO_02062	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PFPHHAOO_02063	6.05e-290	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
PFPHHAOO_02064	9.71e-157	-	-	-	S	-	-	-	SNARE associated Golgi protein
PFPHHAOO_02065	3.33e-53	uvrA2	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC, A subunit
PFPHHAOO_02066	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
PFPHHAOO_02067	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
PFPHHAOO_02068	1.89e-35	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
PFPHHAOO_02069	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PFPHHAOO_02070	3.21e-115	-	-	-	-	-	-	-	-
PFPHHAOO_02071	1.33e-47	-	-	-	-	-	-	-	-
PFPHHAOO_02072	9.22e-129	-	-	-	K	-	-	-	DNA-templated transcription, initiation
PFPHHAOO_02073	5.37e-37	-	-	-	-	-	-	-	-
PFPHHAOO_02074	1.22e-228	ycsG	-	-	P	-	-	-	Natural resistance-associated macrophage protein
PFPHHAOO_02075	4.64e-130	-	-	-	S	ko:K07160	-	ko00000	LamB/YcsF family
PFPHHAOO_02076	3.88e-260	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
PFPHHAOO_02077	5.44e-51	-	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
PFPHHAOO_02078	1.09e-134	kipA	-	-	E	ko:K06350	-	ko00000	Allophanate hydrolase subunit 2
PFPHHAOO_02079	8.61e-108	kipI	-	-	E	ko:K06351	-	ko00000	Allophanate hydrolase subunit 1
PFPHHAOO_02080	7.19e-53	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
PFPHHAOO_02082	1.9e-135	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
PFPHHAOO_02083	1.13e-68	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
PFPHHAOO_02084	7.48e-194	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
PFPHHAOO_02085	2.31e-81	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
PFPHHAOO_02086	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
PFPHHAOO_02087	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
PFPHHAOO_02088	8.24e-170	-	-	-	L	-	-	-	PFAM Integrase catalytic region
PFPHHAOO_02089	1.17e-149	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
PFPHHAOO_02094	2.13e-85	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
PFPHHAOO_02095	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
PFPHHAOO_02097	1.98e-278	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
PFPHHAOO_02098	8.32e-226	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
PFPHHAOO_02099	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
PFPHHAOO_02100	2.62e-204	-	-	-	EG	-	-	-	EamA-like transporter family
PFPHHAOO_02101	7.33e-48	-	-	-	Q	-	-	-	pyridine nucleotide-disulphide oxidoreductase
PFPHHAOO_02102	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
PFPHHAOO_02103	4.66e-148	-	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
PFPHHAOO_02104	3.87e-161	pgm3	-	-	G	-	-	-	phosphoglycerate mutase
PFPHHAOO_02105	4.64e-294	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PFPHHAOO_02106	5.25e-45	-	-	-	S	-	-	-	Transglycosylase associated protein
PFPHHAOO_02107	2.63e-09	-	-	-	S	-	-	-	CsbD-like
PFPHHAOO_02108	3.05e-230	-	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PFPHHAOO_02109	0.0	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
PFPHHAOO_02110	1.76e-122	-	-	-	K	-	-	-	Transcriptional regulator (TetR family)
PFPHHAOO_02111	6.09e-53	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	positive regulation of macromolecule biosynthetic process
PFPHHAOO_02112	9e-191	-	-	-	-	-	-	-	-
PFPHHAOO_02113	5.45e-35	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
PFPHHAOO_02114	4.26e-107	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
PFPHHAOO_02115	2.86e-127	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
PFPHHAOO_02116	1.78e-97	-	-	-	F	-	-	-	Nudix hydrolase
PFPHHAOO_02117	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
PFPHHAOO_02118	3.27e-294	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
PFPHHAOO_02119	8.76e-64	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
PFPHHAOO_02120	7.27e-190	-	-	-	S	ko:K06889	-	ko00000	Hydrolases of the alpha beta superfamily
PFPHHAOO_02121	2.56e-249	adhP	1.1.1.1	-	C	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
PFPHHAOO_02122	2.81e-101	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
PFPHHAOO_02123	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
PFPHHAOO_02124	8.51e-143	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
PFPHHAOO_02125	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PFPHHAOO_02126	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PFPHHAOO_02127	1.29e-260	-	-	-	-	-	-	-	-
PFPHHAOO_02128	8.83e-141	comC	3.4.23.43	-	NOU	ko:K02236,ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	Type II secretory pathway prepilin signal peptidase PulO and related peptidases
PFPHHAOO_02129	2.51e-94	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PFPHHAOO_02130	2.06e-108	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
PFPHHAOO_02131	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PFPHHAOO_02132	1.28e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
PFPHHAOO_02133	5.45e-153	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PFPHHAOO_02134	6.64e-139	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
PFPHHAOO_02135	3.61e-61	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
PFPHHAOO_02136	1.16e-203	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PFPHHAOO_02137	5.72e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PFPHHAOO_02138	4.36e-70	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PFPHHAOO_02139	9.81e-157	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PFPHHAOO_02140	1.96e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PFPHHAOO_02141	5.49e-38	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
PFPHHAOO_02142	1.1e-55	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PFPHHAOO_02143	3.62e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PFPHHAOO_02144	2.58e-65	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PFPHHAOO_02145	7.42e-125	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PFPHHAOO_02146	4.97e-40	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PFPHHAOO_02147	1.54e-87	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PFPHHAOO_02148	2.14e-123	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PFPHHAOO_02149	5.03e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PFPHHAOO_02150	3.45e-111	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PFPHHAOO_02151	5.94e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
PFPHHAOO_02152	8.6e-93	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
PFPHHAOO_02153	9.61e-305	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
PFPHHAOO_02154	6.16e-159	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
PFPHHAOO_02155	2.41e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PFPHHAOO_02156	5.79e-21	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
PFPHHAOO_02157	2.19e-75	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PFPHHAOO_02158	1.62e-83	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PFPHHAOO_02159	2.19e-220	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PFPHHAOO_02160	8.08e-83	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
PFPHHAOO_02161	1.71e-177	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PFPHHAOO_02162	3.12e-193	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PFPHHAOO_02163	6.79e-180	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PFPHHAOO_02164	1.75e-181	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
PFPHHAOO_02165	9.25e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PFPHHAOO_02166	1.61e-84	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
PFPHHAOO_02167	5.21e-179	budC	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	reductase
PFPHHAOO_02168	4.65e-143	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
PFPHHAOO_02169	2.75e-130	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
PFPHHAOO_02170	2.34e-265	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
PFPHHAOO_02171	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
PFPHHAOO_02172	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PFPHHAOO_02173	1.11e-260	camS	-	-	S	-	-	-	sex pheromone
PFPHHAOO_02174	2.75e-66	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PFPHHAOO_02175	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
PFPHHAOO_02176	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PFPHHAOO_02177	4.16e-236	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
PFPHHAOO_02178	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PFPHHAOO_02179	6.22e-51	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
PFPHHAOO_02180	3.81e-83	-	-	-	K	-	-	-	LytTr DNA-binding domain
PFPHHAOO_02181	9.94e-158	cylB	-	-	V	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
PFPHHAOO_02182	7.33e-160	-	-	-	V	ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PFPHHAOO_02183	0.0	-	-	-	L	-	-	-	Recombinase
PFPHHAOO_02184	6.21e-292	-	-	-	L	-	-	-	Recombinase zinc beta ribbon domain
PFPHHAOO_02185	6.18e-26	-	-	-	-	-	-	-	-
PFPHHAOO_02186	4.59e-40	-	-	-	S	-	-	-	Bacteriophage holin family
PFPHHAOO_02187	2.78e-71	-	-	-	S	-	-	-	Phage head-tail joining protein
PFPHHAOO_02188	1.16e-52	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
PFPHHAOO_02189	8.27e-235	-	-	-	S	-	-	-	Phage capsid family
PFPHHAOO_02190	1.27e-115	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
PFPHHAOO_02191	8.85e-164	-	-	-	F	-	-	-	NUDIX domain
PFPHHAOO_02192	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PFPHHAOO_02193	3.18e-133	pncA	-	-	Q	-	-	-	Isochorismatase family
PFPHHAOO_02194	6.17e-38	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
PFPHHAOO_02195	9.17e-250	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
PFPHHAOO_02196	6.75e-28	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
PFPHHAOO_02197	1.14e-178	-	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
PFPHHAOO_02198	2.41e-179	-	-	-	S	-	-	-	Membrane
PFPHHAOO_02199	1.36e-96	-	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase
PFPHHAOO_02200	1.14e-27	-	-	-	-	-	-	-	-
PFPHHAOO_02201	8.27e-111	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
PFPHHAOO_02202	3.64e-307	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
PFPHHAOO_02203	1.04e-60	-	-	-	-	-	-	-	-
PFPHHAOO_02204	1.95e-109	uspA	-	-	T	-	-	-	universal stress protein
PFPHHAOO_02205	3.29e-259	araR	-	-	K	ko:K02103	-	ko00000,ko03000	Transcriptional regulator
PFPHHAOO_02206	4.68e-198	yvgN	-	-	S	-	-	-	Aldo keto reductase
PFPHHAOO_02207	2.65e-38	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
PFPHHAOO_02208	1.9e-66	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
PFPHHAOO_02209	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
PFPHHAOO_02210	1.34e-178	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
PFPHHAOO_02211	0.0	araB	2.7.1.16	-	G	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	carbohydrate kinase FGGY
PFPHHAOO_02212	0.0	araP	-	-	U	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
PFPHHAOO_02213	8.63e-190	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
PFPHHAOO_02214	7.38e-274	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
PFPHHAOO_02215	8.55e-64	gcsH2	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	glycine cleavage
PFPHHAOO_02216	9.49e-282	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
PFPHHAOO_02217	4.61e-44	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
PFPHHAOO_02218	2.57e-227	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
PFPHHAOO_02219	4.97e-307	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PFPHHAOO_02220	1.76e-45	ywzB	-	-	S	-	-	-	Protein of unknown function (DUF1146)
PFPHHAOO_02221	7.36e-89	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
PFPHHAOO_02222	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PFPHHAOO_02223	7.51e-212	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PFPHHAOO_02224	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PFPHHAOO_02225	6.84e-121	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PFPHHAOO_02226	1.07e-95	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PFPHHAOO_02227	1.26e-29	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PFPHHAOO_02228	4.63e-162	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
PFPHHAOO_02229	2.8e-294	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
PFPHHAOO_02230	1.41e-167	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
PFPHHAOO_02231	1.65e-246	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
PFPHHAOO_02232	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PFPHHAOO_02233	6.68e-150	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PFPHHAOO_02234	1.22e-291	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PFPHHAOO_02235	1.09e-250	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
PFPHHAOO_02236	9.58e-211	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
PFPHHAOO_02237	1.73e-248	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PFPHHAOO_02238	6.8e-140	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
PFPHHAOO_02239	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Mur ligase, middle domain
PFPHHAOO_02240	2.82e-172	-	-	-	S	ko:K07009	-	ko00000	CobB/CobQ-like glutamine amidotransferase domain
PFPHHAOO_02242	3.26e-296	potE	-	-	U	ko:K03756,ko:K03758	-	ko00000,ko02000	Amino acid permease
PFPHHAOO_02243	0.0	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
PFPHHAOO_02244	1.24e-103	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
PFPHHAOO_02245	1.54e-289	arcA	3.5.3.6	-	E	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	ko00000,ko00001,ko01000	Arginine
PFPHHAOO_02246	3.4e-232	ampC	-	-	V	-	-	-	Beta-lactamase
PFPHHAOO_02247	9.2e-67	-	-	-	-	-	-	-	-
PFPHHAOO_02248	1.15e-263	-	-	-	M	-	-	-	domain protein
PFPHHAOO_02249	0.0	-	-	-	M	-	-	-	domain protein
PFPHHAOO_02250	2.44e-137	-	-	-	-	-	-	-	-
PFPHHAOO_02251	2.49e-169	int2	-	-	L	-	-	-	Belongs to the 'phage' integrase family
PFPHHAOO_02252	1.17e-20	-	-	-	S	-	-	-	sequence-specific DNA binding
PFPHHAOO_02253	2.16e-20	-	-	-	-	-	-	-	-
PFPHHAOO_02254	4.91e-55	-	-	-	S	-	-	-	Phage regulatory protein Rha (Phage_pRha)
PFPHHAOO_02255	5.44e-07	-	-	-	S	-	-	-	Helix-turn-helix domain
PFPHHAOO_02261	1.99e-13	-	-	-	L	-	-	-	DnaD domain protein
PFPHHAOO_02264	1.37e-86	-	-	-	-	-	-	-	-
PFPHHAOO_02267	1.42e-71	-	-	-	-	-	-	-	-
PFPHHAOO_02269	5.75e-124	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
PFPHHAOO_02270	2.91e-98	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
PFPHHAOO_02271	3.72e-48	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
PFPHHAOO_02272	1.5e-74	-	-	-	-	-	-	-	-
PFPHHAOO_02274	7.13e-110	-	-	-	-	-	-	-	-
PFPHHAOO_02275	0.0	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
PFPHHAOO_02276	2.18e-80	-	-	-	S	-	-	-	Cupredoxin-like domain
PFPHHAOO_02277	7.03e-134	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
PFPHHAOO_02278	1.62e-203	-	-	-	EG	-	-	-	EamA-like transporter family
PFPHHAOO_02279	3.94e-221	arcC	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	Belongs to the carbamate kinase family
PFPHHAOO_02280	7.57e-243	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
PFPHHAOO_02281	1.06e-198	-	-	-	KT	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	YcbB domain
PFPHHAOO_02282	3.42e-41	xylB	2.7.1.17, 2.7.1.53	-	G	ko:K00854,ko:K00880	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the FGGY kinase family
PFPHHAOO_02284	1.1e-35	-	-	-	-	-	-	-	-
PFPHHAOO_02285	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
PFPHHAOO_02286	1.07e-138	maa3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
PFPHHAOO_02287	2.14e-197	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
PFPHHAOO_02288	0.0	yclK	-	-	T	-	-	-	Histidine kinase
PFPHHAOO_02289	4e-174	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
PFPHHAOO_02291	6.22e-107	lytE	-	-	M	-	-	-	Lysin motif
PFPHHAOO_02292	5.46e-191	-	-	-	S	-	-	-	Cof-like hydrolase
PFPHHAOO_02293	6.2e-103	-	-	-	K	-	-	-	Transcriptional regulator
PFPHHAOO_02294	0.0	oatA	-	-	I	-	-	-	Acyltransferase
PFPHHAOO_02295	3e-69	-	-	-	-	-	-	-	-
PFPHHAOO_02296	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
PFPHHAOO_02297	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PFPHHAOO_02298	4.67e-164	ybbR	-	-	S	-	-	-	YbbR-like protein
PFPHHAOO_02299	6.61e-195	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
PFPHHAOO_02300	0.0	fucP	-	-	G	ko:K02429	-	ko00000,ko02000	Major Facilitator Superfamily
PFPHHAOO_02301	1.01e-87	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
PFPHHAOO_02302	1.25e-211	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PFPHHAOO_02303	2.76e-215	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
PFPHHAOO_02304	7.18e-131	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
PFPHHAOO_02305	2.92e-98	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
PFPHHAOO_02306	2.63e-115	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
PFPHHAOO_02307	3.44e-105	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
PFPHHAOO_02308	1.38e-228	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
PFPHHAOO_02309	1.07e-173	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PFPHHAOO_02310	9.61e-137	-	-	-	-	-	-	-	-
PFPHHAOO_02311	7.73e-109	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
PFPHHAOO_02312	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
PFPHHAOO_02313	9.44e-187	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Serine aminopeptidase, S33
PFPHHAOO_02314	1.43e-47	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
PFPHHAOO_02315	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
PFPHHAOO_02316	1.81e-316	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
PFPHHAOO_02317	0.0	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
PFPHHAOO_02318	1.45e-181	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
PFPHHAOO_02319	1.04e-287	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
PFPHHAOO_02320	1.31e-243	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
PFPHHAOO_02322	4.72e-134	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins