ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
EMKMLPHE_00001 1.37e-71 - - - S - - - Uncharacterised protein family (UPF0236)
EMKMLPHE_00002 9.57e-52 - - - S - - - Uncharacterised protein family (UPF0236)
EMKMLPHE_00003 7.33e-126 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
EMKMLPHE_00004 7.76e-20 - - - - - - - -
EMKMLPHE_00006 1.91e-77 - - - D - - - AAA domain
EMKMLPHE_00008 5.33e-05 - - - L - - - Resolvase, N terminal domain
EMKMLPHE_00009 0.0 - - - LV - - - site-specific DNA-methyltransferase (adenine-specific) activity
EMKMLPHE_00010 7.24e-74 - - - L - - - Resolvase, N terminal domain
EMKMLPHE_00011 4.01e-73 - - - L ko:K07497 - ko00000 hmm pf00665
EMKMLPHE_00012 1.55e-106 - - - L ko:K07497 - ko00000 hmm pf00665
EMKMLPHE_00013 5.66e-98 - - - L - - - Helix-turn-helix domain
EMKMLPHE_00014 0.000558 - - - - - - - -
EMKMLPHE_00015 1.37e-71 - - - S - - - Uncharacterised protein family (UPF0236)
EMKMLPHE_00016 9.57e-52 - - - S - - - Uncharacterised protein family (UPF0236)
EMKMLPHE_00018 3.83e-70 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
EMKMLPHE_00019 4.75e-240 - - - L ko:K07484 - ko00000 Transposase IS66 family
EMKMLPHE_00020 3.39e-92 - - - L - - - An automated process has identified a potential problem with this gene model
EMKMLPHE_00021 2.39e-91 - - - L - - - Phage integrase, N-terminal SAM-like domain
EMKMLPHE_00022 6.74e-48 - - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-strand binding protein family
EMKMLPHE_00023 1.32e-127 nicK - - L ko:K07467 - ko00000 Replication initiation factor
EMKMLPHE_00025 2.57e-67 - - - L - - - Lactococcus lactis RepB C-terminus
EMKMLPHE_00026 1.6e-38 - - - L - - - Integrase
EMKMLPHE_00027 1.09e-202 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EMKMLPHE_00028 1.22e-130 - - - L ko:K07482 - ko00000 Helix-turn-helix domain
EMKMLPHE_00030 8.75e-146 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EMKMLPHE_00031 9.7e-162 mhpD - - Q ko:K02509 ko00350,ko01120,map00350,map01120 ko00000,ko00001,ko01000 hydratase
EMKMLPHE_00034 3.83e-70 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
EMKMLPHE_00035 4.75e-240 - - - L ko:K07484 - ko00000 Transposase IS66 family
EMKMLPHE_00036 3.39e-92 - - - L - - - An automated process has identified a potential problem with this gene model
EMKMLPHE_00037 5.21e-179 budC 1.1.1.304, 1.1.1.76 - IQ ko:K03366 ko00650,map00650 ko00000,ko00001,ko01000 reductase
EMKMLPHE_00038 4.65e-143 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
EMKMLPHE_00039 2.75e-130 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
EMKMLPHE_00040 2.34e-265 purK2 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EMKMLPHE_00041 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
EMKMLPHE_00042 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EMKMLPHE_00043 1.11e-260 camS - - S - - - sex pheromone
EMKMLPHE_00044 2.75e-66 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EMKMLPHE_00045 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
EMKMLPHE_00046 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EMKMLPHE_00047 4.16e-236 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
EMKMLPHE_00048 0.0 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EMKMLPHE_00049 6.22e-51 - - - S - - - Protein of unknown function (DUF3021)
EMKMLPHE_00050 3.81e-83 - - - K - - - LytTr DNA-binding domain
EMKMLPHE_00051 9.94e-158 cylB - - V ko:K11051 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 type transporter
EMKMLPHE_00052 7.33e-160 - - - V ko:K11050 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
EMKMLPHE_00053 0.0 - - - L - - - Recombinase
EMKMLPHE_00054 6.21e-292 - - - L - - - Recombinase zinc beta ribbon domain
EMKMLPHE_00055 6.18e-26 - - - - - - - -
EMKMLPHE_00056 4.59e-40 - - - S - - - Bacteriophage holin family
EMKMLPHE_00057 2.78e-71 - - - S - - - Phage head-tail joining protein
EMKMLPHE_00058 1.16e-52 - - - S - - - Phage gp6-like head-tail connector protein
EMKMLPHE_00059 8.27e-235 - - - S - - - Phage capsid family
EMKMLPHE_00060 1.27e-115 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EMKMLPHE_00061 8.85e-164 - - - F - - - NUDIX domain
EMKMLPHE_00062 0.0 nadC2 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EMKMLPHE_00063 3.18e-133 pncA - - Q - - - Isochorismatase family
EMKMLPHE_00064 3.39e-92 - - - L - - - An automated process has identified a potential problem with this gene model
EMKMLPHE_00065 4.75e-240 - - - L ko:K07484 - ko00000 Transposase IS66 family
EMKMLPHE_00066 3.83e-70 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
EMKMLPHE_00068 5.71e-23 cas9 - - L ko:K09952 - ko00000,ko01000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
EMKMLPHE_00069 3.99e-143 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EMKMLPHE_00070 7.44e-51 cas2 - - L ko:K09951 - ko00000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EMKMLPHE_00071 4.91e-59 - - - S - - - CRISPR-associated protein (Cas_Csn2)
EMKMLPHE_00072 1.11e-237 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
EMKMLPHE_00073 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
EMKMLPHE_00074 0.0 lacZ 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 -beta-galactosidase
EMKMLPHE_00075 5.41e-227 hepT 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
EMKMLPHE_00076 4.67e-203 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
EMKMLPHE_00077 6.41e-184 XK27_00940 3.5.1.9 - S ko:K07130 ko00380,ko00630,ko01100,map00380,map00630,map01100 ko00000,ko00001,ko00002,ko01000 Putative cyclase
EMKMLPHE_00078 3.29e-282 - 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
EMKMLPHE_00079 3.54e-165 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
EMKMLPHE_00080 5.18e-291 mdtG2 - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
EMKMLPHE_00081 1.73e-215 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
EMKMLPHE_00082 2.48e-57 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EMKMLPHE_00083 3.2e-84 - - - L ko:K07491 - ko00000 Transposase IS200 like
EMKMLPHE_00084 8.01e-232 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
EMKMLPHE_00085 3.39e-92 - - - L - - - An automated process has identified a potential problem with this gene model
EMKMLPHE_00086 4.75e-240 - - - L ko:K07484 - ko00000 Transposase IS66 family
EMKMLPHE_00087 3.83e-70 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
EMKMLPHE_00089 7.1e-198 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
EMKMLPHE_00090 6.86e-195 - - - M - - - Glycosyl transferase family group 2
EMKMLPHE_00091 1.15e-40 - - - M - - - Glycosyl transferase family group 2
EMKMLPHE_00093 2.96e-285 aadAT - - EK ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko01000 Aminotransferase, class I
EMKMLPHE_00094 8.31e-158 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
EMKMLPHE_00095 1.39e-92 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EMKMLPHE_00096 1.1e-126 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
EMKMLPHE_00097 7.11e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
EMKMLPHE_00098 9.18e-31 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
EMKMLPHE_00099 1.82e-175 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EMKMLPHE_00100 2.95e-92 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EMKMLPHE_00101 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
EMKMLPHE_00102 5.49e-262 yacL - - S - - - domain protein
EMKMLPHE_00103 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EMKMLPHE_00104 8.07e-128 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
EMKMLPHE_00105 4.04e-67 yjdJ - - S ko:K06975 - ko00000 GCN5-related N-acetyl-transferase
EMKMLPHE_00106 2.92e-161 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EMKMLPHE_00107 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
EMKMLPHE_00108 7.93e-177 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
EMKMLPHE_00109 4.11e-172 - - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
EMKMLPHE_00110 3.36e-154 tcyB - - E ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
EMKMLPHE_00111 5.21e-275 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
EMKMLPHE_00112 4.95e-213 - - - I - - - alpha/beta hydrolase fold
EMKMLPHE_00113 5.05e-171 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EMKMLPHE_00114 0.0 - - - S - - - Bacterial membrane protein, YfhO
EMKMLPHE_00115 6.15e-234 lacM 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase
EMKMLPHE_00116 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
EMKMLPHE_00118 3.74e-108 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
EMKMLPHE_00119 0.0 tex - - K ko:K06959 - ko00000 Tex-like protein N-terminal domain protein
EMKMLPHE_00120 1.76e-195 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
EMKMLPHE_00121 0.0 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EMKMLPHE_00122 3.54e-165 yvoA_2 - - K ko:K03710 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
EMKMLPHE_00123 4.13e-167 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
EMKMLPHE_00124 0.0 - - - P ko:K07085 - ko00000 Predicted Permease Membrane Region
EMKMLPHE_00125 4.55e-315 - - - EGP - - - Major Facilitator
EMKMLPHE_00126 1.14e-145 - - - - - - - -
EMKMLPHE_00129 5.86e-190 - - - S - - - Calcineurin-like phosphoesterase
EMKMLPHE_00130 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
EMKMLPHE_00133 5.51e-49 - - - L ko:K07484 - ko00000 Transposase IS66 family
EMKMLPHE_00134 5.04e-113 - - - L ko:K07484 - ko00000 Transposase IS66 family
EMKMLPHE_00135 3.39e-92 - - - L - - - An automated process has identified a potential problem with this gene model
EMKMLPHE_00136 4.75e-240 - - - L ko:K07484 - ko00000 Transposase IS66 family
EMKMLPHE_00137 3.83e-70 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
EMKMLPHE_00140 3.39e-92 - - - L - - - An automated process has identified a potential problem with this gene model
EMKMLPHE_00141 4.75e-240 - - - L ko:K07484 - ko00000 Transposase IS66 family
EMKMLPHE_00142 3.83e-70 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
EMKMLPHE_00145 8.91e-102 - - - D - - - nuclear chromosome segregation
EMKMLPHE_00146 7.31e-18 - - - S - - - AAA ATPase domain
EMKMLPHE_00147 2.12e-44 - - - S - - - Psort location Cytoplasmic, score 8.96
EMKMLPHE_00148 2.06e-17 - - - - - - - -
EMKMLPHE_00149 1.79e-123 - - - L - - - Helix-turn-helix domain
EMKMLPHE_00150 1.44e-170 - - - O - - - Bacterial dnaA protein
EMKMLPHE_00151 6.69e-304 - - - L - - - Integrase core domain
EMKMLPHE_00152 3.39e-92 - - - L - - - An automated process has identified a potential problem with this gene model
EMKMLPHE_00153 4.75e-240 - - - L ko:K07484 - ko00000 Transposase IS66 family
EMKMLPHE_00154 3.83e-70 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
EMKMLPHE_00156 9.27e-220 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
EMKMLPHE_00157 2.76e-215 lutA - - C ko:K18928 - ko00000 Cysteine-rich domain
EMKMLPHE_00158 0.0 lutB - - C ko:K18929 - ko00000 4Fe-4S dicluster domain
EMKMLPHE_00159 1.5e-176 lutC - - S ko:K00782 - ko00000 LUD domain
EMKMLPHE_00160 1.09e-215 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
EMKMLPHE_00161 9.42e-234 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
EMKMLPHE_00162 9.5e-200 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EMKMLPHE_00163 3.96e-226 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EMKMLPHE_00164 1.88e-68 yvlD - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
EMKMLPHE_00165 4.27e-66 - - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain protein
EMKMLPHE_00166 1.58e-238 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EMKMLPHE_00167 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
EMKMLPHE_00168 3.44e-148 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
EMKMLPHE_00169 1.85e-104 yjcF 3.5.4.33, 4.4.1.8 - K ko:K02348,ko:K07000,ko:K11991,ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007,ko03016 protein acetylation
EMKMLPHE_00170 1.36e-248 - - - S - - - Protein of unknown function (DUF3114)
EMKMLPHE_00171 0.0 gshA 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
EMKMLPHE_00172 2.16e-212 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
EMKMLPHE_00173 1.46e-135 - 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
EMKMLPHE_00174 4.62e-81 - - - S - - - Domain of unknown function (DUF4828)
EMKMLPHE_00175 1.26e-243 mocA - - S - - - Oxidoreductase
EMKMLPHE_00176 9.46e-298 yfmL - - L - - - DEAD DEAH box helicase
EMKMLPHE_00178 2.09e-266 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
EMKMLPHE_00179 1e-72 - - - - - - - -
EMKMLPHE_00180 2.45e-88 gtcA - - S - - - Teichoic acid glycosylation protein
EMKMLPHE_00181 1.92e-102 ykuP - - C ko:K03839 - ko00000 Flavodoxin
EMKMLPHE_00182 4.96e-216 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
EMKMLPHE_00183 1.69e-281 arcT - - E - - - Aminotransferase
EMKMLPHE_00184 0.0 arcD - - E ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
EMKMLPHE_00185 0.0 potE - - E - - - Amino Acid
EMKMLPHE_00186 5.01e-197 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
EMKMLPHE_00187 1.26e-46 - - - S - - - Protein of unknown function (DUF2922)
EMKMLPHE_00188 2.53e-42 - - - - - - - -
EMKMLPHE_00189 4.55e-172 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
EMKMLPHE_00190 1.57e-188 cps1D - - M - - - Domain of unknown function (DUF4422)
EMKMLPHE_00191 7.05e-219 yfdH - GT2 M ko:K12999 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
EMKMLPHE_00192 2.23e-150 - - - M - - - Bacterial sugar transferase
EMKMLPHE_00193 0.0 spoIIQ - - M ko:K06386 - ko00000 Peptidase family M23
EMKMLPHE_00194 6.74e-53 - - - K - - - Transcriptional regulator, HxlR family
EMKMLPHE_00195 2.21e-213 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
EMKMLPHE_00196 1.31e-189 epsB - - M - - - biosynthesis protein
EMKMLPHE_00197 3.68e-155 ywqD - - D - - - Capsular exopolysaccharide family
EMKMLPHE_00198 9.5e-62 - - - M ko:K13012 - ko00000,ko01005 Bacterial sugar transferase
EMKMLPHE_00199 8.43e-43 wbiF - - S ko:K07011 - ko00000 glycosyl transferase
EMKMLPHE_00200 1.04e-55 - - - S - - - Hexapeptide repeat of succinyl-transferase
EMKMLPHE_00201 2.27e-124 - - - M - - - Glycosyl transferases group 1
EMKMLPHE_00202 4.5e-45 - - - M - - - Glycosyl transferase family 2
EMKMLPHE_00203 6.67e-46 - - - M - - - Glycosyltransferase like family 2
EMKMLPHE_00205 5.65e-123 - - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EMKMLPHE_00206 1.58e-205 rfbA 2.7.7.24 - H ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EMKMLPHE_00207 7.93e-140 rfbC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
EMKMLPHE_00208 1.15e-263 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
EMKMLPHE_00209 0.0 - 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Thioredoxin domain
EMKMLPHE_00210 3.25e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Peroxiredoxin
EMKMLPHE_00211 3.37e-193 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
EMKMLPHE_00212 3.55e-154 sdhB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
EMKMLPHE_00215 8.01e-232 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
EMKMLPHE_00216 2.99e-51 - - - L ko:K07491 - ko00000 Transposase IS200 like
EMKMLPHE_00217 7.03e-33 - - - - - - - -
EMKMLPHE_00218 1.88e-131 - - - V - - - VanZ like family
EMKMLPHE_00219 2.01e-302 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
EMKMLPHE_00220 1.46e-110 perR - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
EMKMLPHE_00221 0.0 - - - EGP - - - Major Facilitator
EMKMLPHE_00222 1.28e-120 tag1 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
EMKMLPHE_00223 2.71e-280 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EMKMLPHE_00224 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
EMKMLPHE_00225 1.02e-55 - - - - - - - -
EMKMLPHE_00226 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
EMKMLPHE_00227 9.73e-194 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EMKMLPHE_00228 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
EMKMLPHE_00229 2.18e-112 - - - T - - - Belongs to the universal stress protein A family
EMKMLPHE_00230 1.4e-225 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
EMKMLPHE_00231 3.06e-150 dgk2 - - F - - - deoxynucleoside kinase
EMKMLPHE_00232 1.53e-146 - - - - - - - -
EMKMLPHE_00233 8.79e-239 rbsR - - K ko:K02529 - ko00000,ko03000 Periplasmic binding proteins and sugar binding domain of LacI family
EMKMLPHE_00234 1.7e-209 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EMKMLPHE_00235 2.54e-42 - - - - - - - -
EMKMLPHE_00236 8.99e-141 XK27_07085 - - S ko:K07052 - ko00000 CAAX protease self-immunity
EMKMLPHE_00237 9.17e-59 - - - - - - - -
EMKMLPHE_00239 5.19e-90 - - - - - - - -
EMKMLPHE_00240 8.28e-73 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EMKMLPHE_00241 1.46e-117 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
EMKMLPHE_00242 1.94e-135 folE 2.7.6.3, 3.5.4.16 - F ko:K00950,ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase 1
EMKMLPHE_00243 8.72e-280 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
EMKMLPHE_00244 1.12e-131 folQ 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Ham1 family
EMKMLPHE_00245 6.22e-266 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 dihydropteroate synthase
EMKMLPHE_00246 1.88e-60 - - - - - - - -
EMKMLPHE_00247 2.47e-53 - - - - - - - -
EMKMLPHE_00249 2.15e-210 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
EMKMLPHE_00250 6.15e-194 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
EMKMLPHE_00251 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
EMKMLPHE_00252 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
EMKMLPHE_00253 2.42e-64 yheA - - S - - - Belongs to the UPF0342 family
EMKMLPHE_00254 1.11e-283 yhaO - - L ko:K03547 - ko00000,ko03400 Ser Thr phosphatase family protein
EMKMLPHE_00255 0.0 yhaN - - L - - - AAA domain
EMKMLPHE_00256 4.08e-176 prsA 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
EMKMLPHE_00258 2.89e-100 hit - - FG ko:K02503 - ko00000,ko04147 histidine triad
EMKMLPHE_00259 3.83e-175 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EMKMLPHE_00260 3.29e-279 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
EMKMLPHE_00261 7.53e-157 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
EMKMLPHE_00262 4.37e-23 - - - S - - - YSIRK type signal peptide
EMKMLPHE_00263 1.79e-18 - 2.1.1.72, 3.1.21.3 AA10,CBM73 M ko:K01154,ko:K02014,ko:K03933,ko:K07316 - ko00000,ko01000,ko02000,ko02048 domain protein
EMKMLPHE_00264 6.19e-16 - 2.1.1.72, 3.1.21.3 AA10,CBM73 M ko:K01154,ko:K02014,ko:K03933,ko:K07316 - ko00000,ko01000,ko02000,ko02048 domain protein
EMKMLPHE_00265 4.35e-76 - 2.1.1.72, 3.1.21.3 AA10,CBM73 M ko:K01154,ko:K02014,ko:K03933,ko:K07316 - ko00000,ko01000,ko02000,ko02048 domain protein
EMKMLPHE_00266 1.59e-14 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
EMKMLPHE_00267 5.09e-302 - - - L - - - Transposase
EMKMLPHE_00268 1.53e-52 - - - - - - - -
EMKMLPHE_00269 0.0 ydaO - - E - - - amino acid
EMKMLPHE_00270 0.0 - - - E - - - amino acid
EMKMLPHE_00271 1.73e-103 - - - S ko:K19055 - ko00000,ko01000,ko03016 Aminoacyl-tRNA editing domain
EMKMLPHE_00272 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
EMKMLPHE_00273 1.83e-59 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EMKMLPHE_00275 4.67e-147 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EMKMLPHE_00276 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
EMKMLPHE_00277 2.93e-233 ykpB 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EMKMLPHE_00278 8.87e-289 mtnE - - E ko:K08969 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
EMKMLPHE_00279 8.63e-180 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Carbon-nitrogen hydrolase
EMKMLPHE_00280 1.48e-176 proB 2.7.2.11 - F ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EMKMLPHE_00281 1.22e-288 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EMKMLPHE_00282 9.93e-168 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EMKMLPHE_00283 1.13e-248 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EMKMLPHE_00284 8e-131 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 Ribosomal-protein-alanine acetyltransferase
EMKMLPHE_00285 2.56e-162 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
EMKMLPHE_00286 2.35e-244 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
EMKMLPHE_00287 7.29e-219 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
EMKMLPHE_00288 0.0 ppk 2.7.4.1 - P ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EMKMLPHE_00289 0.0 ppx3 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
EMKMLPHE_00290 1.43e-174 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
EMKMLPHE_00291 1.06e-198 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EMKMLPHE_00292 1.77e-74 yabA - - L - - - Involved in initiation control of chromosome replication
EMKMLPHE_00293 7.16e-233 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
EMKMLPHE_00294 1.64e-68 yaaQ - - S - - - Cyclic-di-AMP receptor
EMKMLPHE_00295 3.41e-144 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EMKMLPHE_00296 1.57e-50 - - - S - - - Protein of unknown function (DUF2508)
EMKMLPHE_00297 1.65e-140 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EMKMLPHE_00298 5.87e-62 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EMKMLPHE_00299 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EMKMLPHE_00300 1.35e-113 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
EMKMLPHE_00301 9.33e-48 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
EMKMLPHE_00302 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EMKMLPHE_00303 4.45e-253 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EMKMLPHE_00304 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
EMKMLPHE_00305 9.28e-170 - - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
EMKMLPHE_00306 6.31e-126 - - - S - - - Protein of unknown function (DUF1700)
EMKMLPHE_00307 2.79e-75 XK27_06915 - - K ko:K10947 - ko00000,ko03000 transcriptional regulator PadR family
EMKMLPHE_00308 3.29e-62 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
EMKMLPHE_00309 3.05e-49 - - - - - - - -
EMKMLPHE_00310 2.46e-72 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
EMKMLPHE_00311 3.6e-107 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EMKMLPHE_00312 2.25e-59 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
EMKMLPHE_00313 3.39e-92 - - - L - - - An automated process has identified a potential problem with this gene model
EMKMLPHE_00314 4.75e-240 - - - L ko:K07484 - ko00000 Transposase IS66 family
EMKMLPHE_00315 3.83e-70 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
EMKMLPHE_00318 7.69e-75 - - - - - - - -
EMKMLPHE_00319 3.48e-85 - - - - - - - -
EMKMLPHE_00320 1.29e-37 - - - - - - - -
EMKMLPHE_00321 1.29e-194 - - - G - - - Belongs to the phosphoglycerate mutase family
EMKMLPHE_00322 9.68e-159 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
EMKMLPHE_00323 1.95e-131 - - - D ko:K04095 - ko00000,ko03036 Fic/DOC family
EMKMLPHE_00324 1.5e-91 - - - - - - - -
EMKMLPHE_00325 0.0 XK27_00340 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
EMKMLPHE_00326 1.87e-132 - - - L - - - nuclease
EMKMLPHE_00327 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 Putative exonuclease SbcCD, C subunit
EMKMLPHE_00328 3.9e-266 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
EMKMLPHE_00329 1.97e-183 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
EMKMLPHE_00330 0.0 snf - - KL - - - domain protein
EMKMLPHE_00332 2.74e-50 - - - - ko:K18829 - ko00000,ko02048 -
EMKMLPHE_00333 5.1e-89 - - - T ko:K07171 - ko00000,ko01000,ko02048 Toxin-antitoxin system, toxin component, MazF family
EMKMLPHE_00335 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
EMKMLPHE_00336 1.32e-219 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine S-methyltransferase
EMKMLPHE_00337 8.01e-232 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
EMKMLPHE_00338 2.99e-51 - - - L ko:K07491 - ko00000 Transposase IS200 like
EMKMLPHE_00339 6.49e-228 - - - L - - - Transposase DDE domain
EMKMLPHE_00341 9.6e-35 - - - S - - - Acyltransferase family
EMKMLPHE_00342 0.0 - 2.4.1.5 GH13 G ko:K00689 ko00500,ko02020,map00500,map02020 ko00000,ko00001,ko01000 Glycosyl hydrolase family 70
EMKMLPHE_00343 6.49e-228 - - - L - - - Transposase DDE domain
EMKMLPHE_00344 3.2e-61 yphJ 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 decarboxylase
EMKMLPHE_00345 1.24e-80 yphH - - S - - - Cupin domain
EMKMLPHE_00346 3.18e-133 - 1.1.1.65 - C ko:K05275 ko00750,ko01100,ko01120,map00750,map01100,map01120 ko00000,ko00001,ko01000 Aldo/keto reductase family
EMKMLPHE_00347 2.62e-31 - - - EGP ko:K08166 - ko00000,ko02000 Major Facilitator Superfamily
EMKMLPHE_00349 1.58e-90 ltrA - - S - - - Bacterial low temperature requirement A protein (LtrA)
EMKMLPHE_00350 1.33e-155 - - - EGP - - - Major Facilitator Superfamily
EMKMLPHE_00351 2.3e-151 - - - GM - - - NmrA-like family
EMKMLPHE_00352 9.38e-185 - - - C - - - Aldo keto reductase
EMKMLPHE_00353 3.71e-142 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
EMKMLPHE_00354 9.36e-178 akr5f 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
EMKMLPHE_00355 2.05e-112 - - - K - - - Transcriptional regulator
EMKMLPHE_00359 8.48e-28 - - - T ko:K06919 - ko00000 Phage plasmid primase, P4 family
EMKMLPHE_00361 3.83e-70 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
EMKMLPHE_00362 4.75e-240 - - - L ko:K07484 - ko00000 Transposase IS66 family
EMKMLPHE_00363 3.39e-92 - - - L - - - An automated process has identified a potential problem with this gene model
EMKMLPHE_00364 6.49e-228 - - - L - - - Transposase DDE domain
EMKMLPHE_00365 1.28e-18 - - - - - - - -
EMKMLPHE_00366 2.72e-129 msrA 1.8.4.11 - C ko:K07304 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EMKMLPHE_00367 1.08e-67 yitW - - S - - - Iron-sulfur cluster assembly protein
EMKMLPHE_00368 8.07e-202 - - - - - - - -
EMKMLPHE_00369 1.67e-229 - - - - - - - -
EMKMLPHE_00370 5.52e-112 - - - S - - - Protein conserved in bacteria
EMKMLPHE_00374 3.16e-143 - - - K - - - Transcriptional regulator
EMKMLPHE_00375 2.68e-67 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
EMKMLPHE_00376 8.44e-71 ysxB - - J ko:K07584 - ko00000 Cysteine protease Prp
EMKMLPHE_00377 5.93e-60 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
EMKMLPHE_00378 2.13e-167 - - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EMKMLPHE_00379 3.54e-255 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
EMKMLPHE_00380 1.73e-147 - - - J - - - 2'-5' RNA ligase superfamily
EMKMLPHE_00381 2.27e-93 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
EMKMLPHE_00382 1.84e-91 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EMKMLPHE_00383 3.63e-189 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EMKMLPHE_00384 7.97e-280 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
EMKMLPHE_00385 1.15e-57 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
EMKMLPHE_00386 1.24e-198 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
EMKMLPHE_00387 2.81e-191 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
EMKMLPHE_00388 1.85e-99 argR2 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
EMKMLPHE_00389 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
EMKMLPHE_00390 8.66e-70 - - - - - - - -
EMKMLPHE_00391 3.59e-147 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
EMKMLPHE_00392 6.66e-43 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
EMKMLPHE_00393 5.06e-263 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EMKMLPHE_00394 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EMKMLPHE_00395 5.81e-222 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EMKMLPHE_00396 2.81e-314 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EMKMLPHE_00397 1.17e-165 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
EMKMLPHE_00398 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
EMKMLPHE_00399 2.33e-206 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
EMKMLPHE_00400 4.49e-151 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
EMKMLPHE_00401 4.7e-157 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
EMKMLPHE_00402 1.1e-34 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
EMKMLPHE_00403 1.05e-77 yloU - - S - - - Asp23 family, cell envelope-related function
EMKMLPHE_00404 0.0 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
EMKMLPHE_00405 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EMKMLPHE_00406 5.51e-240 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
EMKMLPHE_00407 1.81e-50 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
EMKMLPHE_00408 1.57e-168 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
EMKMLPHE_00409 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
EMKMLPHE_00410 3.67e-260 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
EMKMLPHE_00411 4.23e-76 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
EMKMLPHE_00412 0.0 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EMKMLPHE_00413 1.21e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
EMKMLPHE_00414 3.74e-53 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
EMKMLPHE_00415 1.47e-116 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EMKMLPHE_00416 5.46e-183 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
EMKMLPHE_00417 0.0 - - - E ko:K03294 - ko00000 amino acid
EMKMLPHE_00418 3.03e-83 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
EMKMLPHE_00419 1.05e-45 - - - - - - - -
EMKMLPHE_00420 8.66e-70 - - - S - - - Mazg nucleotide pyrophosphohydrolase
EMKMLPHE_00421 5.32e-206 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
EMKMLPHE_00422 6.28e-19 - - - - - - - -
EMKMLPHE_00423 0.0 cas9 - - L ko:K09952 - ko00000,ko01000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
EMKMLPHE_00424 3.39e-92 - - - L - - - An automated process has identified a potential problem with this gene model
EMKMLPHE_00425 4.75e-240 - - - L ko:K07484 - ko00000 Transposase IS66 family
EMKMLPHE_00426 3.83e-70 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
EMKMLPHE_00428 6.49e-228 - - - L - - - Transposase DDE domain
EMKMLPHE_00429 1.44e-59 - - - S - - - Glycosyltransferase like family 2
EMKMLPHE_00430 2.97e-32 - - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
EMKMLPHE_00431 5.7e-33 - - - M - - - PFAM Glycosyl transferase family 2
EMKMLPHE_00432 1.07e-49 - - - M - - - Glycosyltransferase sugar-binding region containing DXD motif
EMKMLPHE_00433 7.81e-85 cps2I - - S - - - Psort location CytoplasmicMembrane, score
EMKMLPHE_00435 2.34e-52 - - - M - - - Glycosyltransferase GT-D fold
EMKMLPHE_00436 2.59e-83 wefC - - M - - - Stealth protein CR2, conserved region 2
EMKMLPHE_00437 9.77e-103 - - GT4 G ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like domain
EMKMLPHE_00438 8.24e-63 - - - M ko:K13012 - ko00000,ko01005 Bacterial sugar transferase
EMKMLPHE_00439 3.01e-140 ywqD - - D - - - Capsular exopolysaccharide family
EMKMLPHE_00440 3.06e-126 epsB - - M - - - biosynthesis protein
EMKMLPHE_00441 6.69e-304 - - - L - - - Integrase core domain
EMKMLPHE_00442 1.44e-170 - - - O - - - Bacterial dnaA protein
EMKMLPHE_00443 6.49e-228 - - - L - - - Transposase DDE domain
EMKMLPHE_00444 1.35e-186 - - - C - - - NADH flavin oxidoreductases, Old Yellow Enzyme family
EMKMLPHE_00445 9.5e-110 - - - P - - - Putative esterase
EMKMLPHE_00446 5.43e-120 - - - I - - - acetylesterase activity
EMKMLPHE_00447 4.71e-63 - - - C - - - Flavodoxin
EMKMLPHE_00448 7.46e-105 - - - P - - - esterase
EMKMLPHE_00450 3.97e-75 - - - C - - - Flavodoxin
EMKMLPHE_00451 7.03e-29 - - - P - - - FAD-binding domain
EMKMLPHE_00452 2.54e-19 - - - P - - - FAD-binding domain
EMKMLPHE_00453 1.04e-39 - - - P - - - FAD-binding domain
EMKMLPHE_00454 1.04e-91 - - - C - - - Flavodoxin
EMKMLPHE_00455 3.75e-103 - - - C - - - Flavodoxin
EMKMLPHE_00456 1.99e-70 - - - K - - - Transcriptional regulator
EMKMLPHE_00457 1.02e-90 adhR - - K - - - helix_turn_helix, mercury resistance
EMKMLPHE_00458 1.78e-242 adh2 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
EMKMLPHE_00459 7.07e-181 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EMKMLPHE_00460 1.69e-155 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
EMKMLPHE_00463 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EMKMLPHE_00464 3.6e-208 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
EMKMLPHE_00465 1.23e-135 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
EMKMLPHE_00466 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
EMKMLPHE_00467 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
EMKMLPHE_00468 1.02e-103 - - - F - - - NUDIX domain
EMKMLPHE_00469 7.36e-222 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
EMKMLPHE_00470 6.48e-34 - - - S - - - Belongs to the HesB IscA family
EMKMLPHE_00471 1.96e-35 - - - - - - - -
EMKMLPHE_00473 8.23e-112 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
EMKMLPHE_00474 1.57e-80 asp1 - - S - - - Asp23 family, cell envelope-related function
EMKMLPHE_00475 6.23e-35 - - - - - - - -
EMKMLPHE_00476 3.66e-121 - - - - - - - -
EMKMLPHE_00477 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
EMKMLPHE_00478 3.78e-230 - - - K ko:K02525 - ko00000,ko03000 Transcriptional regulator, LacI family
EMKMLPHE_00479 1.55e-294 gntP - - EG ko:K03299 - ko00000,ko02000 Gluconate
EMKMLPHE_00480 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
EMKMLPHE_00481 2.93e-125 - - - K - - - Acetyltransferase (GNAT) domain
EMKMLPHE_00482 5.09e-302 - - - L - - - Transposase
EMKMLPHE_00483 5.09e-302 - - - L - - - Transposase
EMKMLPHE_00484 4.44e-112 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
EMKMLPHE_00485 3.46e-217 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
EMKMLPHE_00486 1.06e-233 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
EMKMLPHE_00487 4.45e-109 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EMKMLPHE_00488 1.66e-77 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
EMKMLPHE_00489 6.02e-216 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EMKMLPHE_00490 2.5e-188 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
EMKMLPHE_00491 2.5e-233 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
EMKMLPHE_00492 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
EMKMLPHE_00493 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
EMKMLPHE_00494 1.03e-265 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
EMKMLPHE_00495 7.19e-280 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
EMKMLPHE_00496 8.96e-160 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
EMKMLPHE_00497 2.94e-198 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EMKMLPHE_00498 6.7e-303 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
EMKMLPHE_00499 3.79e-40 - - - S - - - Protein of unknown function (DUF2929)
EMKMLPHE_00500 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
EMKMLPHE_00501 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
EMKMLPHE_00502 2.27e-216 yitL - - S ko:K00243 - ko00000 S1 domain
EMKMLPHE_00503 1.93e-210 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
EMKMLPHE_00504 1.23e-84 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EMKMLPHE_00505 5.35e-175 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EMKMLPHE_00506 5.49e-135 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EMKMLPHE_00507 1.49e-164 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
EMKMLPHE_00508 4.74e-86 - - - L - - - Belongs to the 'phage' integrase family
EMKMLPHE_00512 2.64e-96 - - - E - - - IrrE N-terminal-like domain
EMKMLPHE_00513 3.37e-63 - - - K ko:K07727 - ko00000,ko03000 addiction module antidote protein HigA
EMKMLPHE_00516 2.11e-28 - - - - - - - -
EMKMLPHE_00517 3.24e-149 - - - S - - - Protein of unknown function (DUF3102)
EMKMLPHE_00525 5.07e-81 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
EMKMLPHE_00526 9.48e-172 - - - S - - - Putative HNHc nuclease
EMKMLPHE_00527 8.91e-193 - - - L - - - Psort location Cytoplasmic, score
EMKMLPHE_00531 2.03e-26 - - - - - - - -
EMKMLPHE_00532 1.31e-46 - - - - - - - -
EMKMLPHE_00533 5.12e-101 rusA - - L - - - Endodeoxyribonuclease RusA
EMKMLPHE_00539 1.08e-88 - - - Q - - - DNA (cytosine-5-)-methyltransferase activity
EMKMLPHE_00543 3.78e-170 - - - - - - - -
EMKMLPHE_00549 6.12e-166 - - - F - - - deoxynucleoside kinase
EMKMLPHE_00554 5.44e-99 - - - S - - - Transcriptional regulator, RinA family
EMKMLPHE_00556 0.0 - - - - - - - -
EMKMLPHE_00557 7.69e-263 XK27_11280 - - S - - - Psort location CytoplasmicMembrane, score
EMKMLPHE_00566 2.51e-45 - - - L - - - NUMOD4 motif
EMKMLPHE_00567 1.89e-152 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
EMKMLPHE_00572 4.75e-51 - - - S - - - HicB_like antitoxin of bacterial toxin-antitoxin system
EMKMLPHE_00574 6.19e-12 - - - V - - - HNH nucleases
EMKMLPHE_00588 5.01e-69 - - - L - - - HNH nucleases
EMKMLPHE_00589 7.81e-102 - - - L - - - Phage terminase, small subunit
EMKMLPHE_00590 3.3e-114 - - - L - - - Terminase
EMKMLPHE_00591 0.0 - - - L - - - Terminase
EMKMLPHE_00592 1.15e-315 - - - S - - - portal protein
EMKMLPHE_00593 5.4e-177 - 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S14 family
EMKMLPHE_00594 4.1e-272 - - - S - - - Phage capsid family
EMKMLPHE_00596 1.74e-92 - - - S - - - Phage gp6-like head-tail connector protein
EMKMLPHE_00597 2.05e-83 - - - S - - - Phage head-tail joining protein
EMKMLPHE_00598 1.09e-114 - - - - - - - -
EMKMLPHE_00599 1.39e-92 - - - - - - - -
EMKMLPHE_00600 1.24e-170 - - - S - - - Phage tail tube protein
EMKMLPHE_00601 6.2e-89 - - - - - - - -
EMKMLPHE_00602 0.0 - - - L - - - Phage tail tape measure protein TP901
EMKMLPHE_00603 2.08e-199 - - - S - - - Phage tail protein
EMKMLPHE_00604 0.0 - - - M - - - Prophage endopeptidase tail
EMKMLPHE_00605 1.96e-38 - - - - - - - -
EMKMLPHE_00607 5.31e-86 dex 3.2.1.11 GH66 G ko:K05988 ko00500,map00500 ko00000,ko00001,ko01000 Cycloisomaltooligosaccharide glucanotransferase
EMKMLPHE_00608 3.15e-76 - - - S - - - Domain of unknown function (DUF2479)
EMKMLPHE_00610 8.4e-53 - - - - - - - -
EMKMLPHE_00611 2.63e-46 - - - S - - - Bacteriophage holin of superfamily 6 (Holin_LLH)
EMKMLPHE_00612 2.89e-168 lysA2 - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
EMKMLPHE_00614 8.97e-16 - - - - - - - -
EMKMLPHE_00617 2.09e-130 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EMKMLPHE_00618 1.43e-250 - - - S - - - Helix-turn-helix domain
EMKMLPHE_00619 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
EMKMLPHE_00620 1.04e-69 - - - M - - - Lysin motif
EMKMLPHE_00621 2.64e-148 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
EMKMLPHE_00622 1.49e-274 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
EMKMLPHE_00623 6.66e-316 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
EMKMLPHE_00624 1.6e-54 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
EMKMLPHE_00625 1.24e-296 XK27_05225 - - S - - - Tetratricopeptide repeat protein
EMKMLPHE_00626 7.84e-284 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
EMKMLPHE_00627 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 ABC transporter, ATP-binding protein
EMKMLPHE_00628 1.41e-244 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EMKMLPHE_00629 2.78e-118 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EMKMLPHE_00630 1.23e-142 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
EMKMLPHE_00631 6.12e-194 WQ51_01275 - - S - - - EDD domain protein, DegV family
EMKMLPHE_00632 8.88e-217 - - - E - - - lipolytic protein G-D-S-L family
EMKMLPHE_00633 1.16e-140 ypmS - - S - - - Uncharacterized protein conserved in bacteria (DUF2140)
EMKMLPHE_00634 1.33e-47 yozE - - S - - - Belongs to the UPF0346 family
EMKMLPHE_00635 2.43e-205 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EMKMLPHE_00636 5.63e-178 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EMKMLPHE_00637 1.04e-165 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
EMKMLPHE_00638 4.42e-51 int2 - - L - - - Belongs to the 'phage' integrase family
EMKMLPHE_00643 3.39e-92 - - - L - - - An automated process has identified a potential problem with this gene model
EMKMLPHE_00644 4.75e-240 - - - L ko:K07484 - ko00000 Transposase IS66 family
EMKMLPHE_00645 3.83e-70 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
EMKMLPHE_00647 5.09e-302 - - - L - - - Transposase
EMKMLPHE_00648 5.37e-74 - - - S - - - Small secreted protein
EMKMLPHE_00649 5.52e-71 ytpP - - CO - - - Thioredoxin
EMKMLPHE_00650 2.71e-151 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
EMKMLPHE_00651 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
EMKMLPHE_00652 4.56e-154 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
EMKMLPHE_00653 1.61e-93 - - - S - - - Protein of unknown function (DUF1275)
EMKMLPHE_00654 2.26e-21 - - - S - - - Protein of unknown function (DUF1275)
EMKMLPHE_00655 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EMKMLPHE_00656 5.3e-202 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
EMKMLPHE_00657 5.43e-125 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EMKMLPHE_00658 2.82e-105 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EMKMLPHE_00659 7.42e-296 dnaB - - L ko:K03346 - ko00000,ko03032 replication initiation and membrane attachment
EMKMLPHE_00660 8.6e-222 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
EMKMLPHE_00661 1.07e-110 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EMKMLPHE_00662 1.82e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
EMKMLPHE_00663 5.46e-74 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EMKMLPHE_00664 4.48e-205 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
EMKMLPHE_00665 0.0 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
EMKMLPHE_00666 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
EMKMLPHE_00667 3.7e-204 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
EMKMLPHE_00668 4.93e-123 lemA - - S ko:K03744 - ko00000 LemA family
EMKMLPHE_00669 5.7e-114 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EMKMLPHE_00670 1.84e-155 - - - G - - - Belongs to the phosphoglycerate mutase family
EMKMLPHE_00671 3.08e-207 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
EMKMLPHE_00672 8.28e-177 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
EMKMLPHE_00673 3.7e-192 - - - G - - - Right handed beta helix region
EMKMLPHE_00674 0.0 pps 2.7.9.2 - H ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
EMKMLPHE_00675 1.18e-159 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
EMKMLPHE_00676 2.96e-209 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
EMKMLPHE_00677 2.42e-298 pts13C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EMKMLPHE_00678 9.43e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
EMKMLPHE_00679 1.3e-300 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EMKMLPHE_00680 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
EMKMLPHE_00681 2.44e-84 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
EMKMLPHE_00682 6.59e-90 ywiB - - S - - - Domain of unknown function (DUF1934)
EMKMLPHE_00691 1.12e-167 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
EMKMLPHE_00692 1.04e-174 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 alpha subunit
EMKMLPHE_00693 1.19e-183 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EMKMLPHE_00694 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
EMKMLPHE_00695 2.29e-97 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
EMKMLPHE_00696 4.19e-96 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
EMKMLPHE_00697 7.83e-283 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
EMKMLPHE_00698 5.12e-159 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
EMKMLPHE_00699 2.72e-194 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
EMKMLPHE_00700 1.99e-44 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
EMKMLPHE_00701 3.58e-215 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EMKMLPHE_00702 1.94e-100 - - - K - - - Transcriptional regulator, MarR family
EMKMLPHE_00703 1.39e-91 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
EMKMLPHE_00705 3.42e-258 xerS - - L - - - Belongs to the 'phage' integrase family
EMKMLPHE_00706 4.34e-19 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 Levansucrase/Invertase
EMKMLPHE_00707 9.52e-202 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 Levansucrase/Invertase
EMKMLPHE_00708 2.53e-74 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 Levansucrase/Invertase
EMKMLPHE_00709 1.15e-200 rssA - - S - - - Phospholipase, patatin family
EMKMLPHE_00710 9.45e-152 - - - L - - - Integrase
EMKMLPHE_00711 1.55e-195 - - - EG - - - EamA-like transporter family
EMKMLPHE_00712 5.14e-92 - - - L - - - Helix-turn-helix domain
EMKMLPHE_00713 9.51e-95 - - - L - - - PFAM Integrase catalytic region
EMKMLPHE_00714 5.96e-139 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EMKMLPHE_00715 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EMKMLPHE_00716 7.1e-274 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
EMKMLPHE_00717 2.37e-291 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EMKMLPHE_00718 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
EMKMLPHE_00719 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
EMKMLPHE_00720 5.45e-233 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase subunit II
EMKMLPHE_00721 0.0 cydC - - CO ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
EMKMLPHE_00722 0.0 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EMKMLPHE_00723 1.81e-294 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
EMKMLPHE_00724 2.66e-306 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
EMKMLPHE_00725 4.2e-157 radC - - L ko:K03630 - ko00000 DNA repair protein
EMKMLPHE_00726 8.33e-230 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
EMKMLPHE_00727 3.82e-195 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
EMKMLPHE_00728 1.69e-120 mreD - - M ko:K03571 - ko00000,ko03036 rod shape-determining protein MreD
EMKMLPHE_00729 4.45e-141 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
EMKMLPHE_00730 1.45e-151 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
EMKMLPHE_00731 3.32e-204 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
EMKMLPHE_00732 1.87e-288 ymfF - - S - - - Peptidase M16 inactive domain protein
EMKMLPHE_00733 1.92e-316 ymfH - - S - - - Peptidase M16
EMKMLPHE_00734 1.71e-189 - - - S - - - Helix-turn-helix domain
EMKMLPHE_00735 1.16e-133 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EMKMLPHE_00736 6.52e-289 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
EMKMLPHE_00737 6.3e-251 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EMKMLPHE_00738 2.29e-276 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
EMKMLPHE_00739 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EMKMLPHE_00740 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EMKMLPHE_00741 4.34e-131 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
EMKMLPHE_00742 2.74e-242 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
EMKMLPHE_00743 9.79e-239 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
EMKMLPHE_00744 1.44e-59 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
EMKMLPHE_00745 3.56e-233 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
EMKMLPHE_00746 0.0 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
EMKMLPHE_00747 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EMKMLPHE_00748 8.03e-58 yrzL - - S - - - Belongs to the UPF0297 family
EMKMLPHE_00749 3.62e-100 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EMKMLPHE_00750 3.75e-63 yrzB - - S - - - Belongs to the UPF0473 family
EMKMLPHE_00751 1.44e-121 cvpA - - S - - - Colicin V production protein
EMKMLPHE_00752 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
EMKMLPHE_00753 2.86e-72 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
EMKMLPHE_00754 5.82e-124 yslB - - S - - - Protein of unknown function (DUF2507)
EMKMLPHE_00755 1.62e-187 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
EMKMLPHE_00756 2.44e-135 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EMKMLPHE_00757 1.65e-120 - - - S ko:K07095 - ko00000 Phosphoesterase
EMKMLPHE_00758 8.55e-99 ykuL - - S - - - (CBS) domain
EMKMLPHE_00759 3.3e-197 - - - S - - - haloacid dehalogenase-like hydrolase
EMKMLPHE_00760 7.58e-189 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
EMKMLPHE_00761 8.88e-71 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
EMKMLPHE_00762 2.9e-72 - - - - - - - -
EMKMLPHE_00763 4.92e-266 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
EMKMLPHE_00764 7.72e-232 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
EMKMLPHE_00765 1.05e-174 - - - - - - - -
EMKMLPHE_00766 7.07e-168 yebC - - K - - - Transcriptional regulatory protein
EMKMLPHE_00767 1.56e-230 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
EMKMLPHE_00768 6.11e-233 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
EMKMLPHE_00769 6.31e-62 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 competence protein ComGC
EMKMLPHE_00770 2.12e-102 - - - NU ko:K02246 - ko00000,ko00002,ko02044 general secretion pathway protein
EMKMLPHE_00771 1.96e-55 - - - - - - - -
EMKMLPHE_00772 3.12e-90 - - - - ko:K02248 - ko00000,ko00002,ko02044 -
EMKMLPHE_00774 5.43e-191 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
EMKMLPHE_00775 4.36e-283 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EMKMLPHE_00776 1.21e-143 - - - S - - - Calcineurin-like phosphoesterase
EMKMLPHE_00777 2.66e-120 yutD - - S - - - Protein of unknown function (DUF1027)
EMKMLPHE_00778 4.76e-170 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
EMKMLPHE_00779 6.92e-130 - - - S - - - Protein of unknown function (DUF1461)
EMKMLPHE_00780 1.06e-148 dedA - - S ko:K03975 - ko00000 SNARE-like domain protein
EMKMLPHE_00781 1.79e-176 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EMKMLPHE_00782 3.22e-189 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
EMKMLPHE_00783 5.47e-151 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
EMKMLPHE_00784 1.61e-291 - - - P - - - Chloride transporter, ClC family
EMKMLPHE_00785 6.89e-171 - - - L - - - PFAM transposase IS116 IS110 IS902
EMKMLPHE_00786 0.0 agl 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 31 family
EMKMLPHE_00787 4.64e-142 - - - I - - - Acid phosphatase homologues
EMKMLPHE_00788 4.3e-51 - - - L ko:K07484 - ko00000 Transposase IS66 family
EMKMLPHE_00789 5.04e-113 - - - L ko:K07484 - ko00000 Transposase IS66 family
EMKMLPHE_00792 0.0 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
EMKMLPHE_00793 6.65e-136 - - - S - - - GyrI-like small molecule binding domain
EMKMLPHE_00794 1.09e-127 - - - S ko:K07507 - ko00000,ko02000 MgtC family
EMKMLPHE_00795 1.02e-121 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
EMKMLPHE_00796 5.79e-247 flp - - V - - - Beta-lactamase
EMKMLPHE_00797 1.58e-91 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EMKMLPHE_00798 1.27e-115 - - - J ko:K19055 - ko00000,ko01000,ko03016 Aminoacyl-tRNA editing domain
EMKMLPHE_00799 3.74e-67 - - - S - - - Alpha beta hydrolase
EMKMLPHE_00800 1.2e-195 mhpD - - Q ko:K02509 ko00350,ko01120,map00350,map01120 ko00000,ko00001,ko01000 hydratase
EMKMLPHE_00801 4.61e-223 hdhL 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
EMKMLPHE_00802 1.67e-291 aadAT - - EK ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko01000 Aminotransferase, class I
EMKMLPHE_00803 1.45e-214 ypuA - - S - - - Protein of unknown function (DUF1002)
EMKMLPHE_00804 1.99e-235 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase, type I
EMKMLPHE_00805 4.24e-190 - - - K - - - Transcriptional regulator
EMKMLPHE_00806 1.15e-204 akr5f 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
EMKMLPHE_00807 4.71e-128 qorB 1.6.5.2 - GM ko:K19267 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NmrA-like family
EMKMLPHE_00808 6.31e-79 - - - - - - - -
EMKMLPHE_00809 2.72e-164 - - - F - - - glutamine amidotransferase
EMKMLPHE_00810 1.69e-177 - - - T - - - EAL domain
EMKMLPHE_00811 0.0 yijG - GT2 M ko:K11936 ko02026,map02026 ko00000,ko00001,ko01000,ko01003,ko02000 Glycosyl transferase
EMKMLPHE_00812 5.09e-302 - - - L - - - Transposase
EMKMLPHE_00813 1.58e-305 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
EMKMLPHE_00814 2.57e-141 - - - S - - - Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
EMKMLPHE_00815 1.58e-66 azlD - - E - - - Branched-chain amino acid transport
EMKMLPHE_00816 4.42e-153 azlC - - E - - - azaleucine resistance protein AzlC
EMKMLPHE_00817 0.0 - - - K - - - Aminotransferase class I and II
EMKMLPHE_00818 1.52e-239 - - - S - - - amidohydrolase
EMKMLPHE_00819 5.95e-134 - - - L ko:K07497 - ko00000 hmm pf00665
EMKMLPHE_00820 1.73e-48 - - - L - - - PFAM Integrase catalytic region
EMKMLPHE_00822 2.45e-63 - 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase, GNAT family
EMKMLPHE_00823 5.59e-20 - 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase, GNAT family
EMKMLPHE_00824 1.41e-146 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
EMKMLPHE_00825 2.61e-315 yxbA 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp enzyme
EMKMLPHE_00826 0.0 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EMKMLPHE_00827 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
EMKMLPHE_00828 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
EMKMLPHE_00829 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EMKMLPHE_00830 1.08e-170 jag - - S ko:K06346 - ko00000 R3H domain protein
EMKMLPHE_00831 1.21e-171 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EMKMLPHE_00832 1.39e-76 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
EMKMLPHE_00833 7.96e-21 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
EMKMLPHE_00834 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EMKMLPHE_00835 4.03e-263 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
EMKMLPHE_00836 2.21e-46 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain protein YaaA
EMKMLPHE_00837 1.63e-259 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EMKMLPHE_00838 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EMKMLPHE_00839 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EMKMLPHE_00840 4.55e-64 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
EMKMLPHE_00841 1.34e-110 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
EMKMLPHE_00842 9.36e-48 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EMKMLPHE_00843 1.31e-97 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EMKMLPHE_00844 1.67e-23 deoR - - K ko:K05346 - ko00000,ko03000 sugar-binding domain protein
EMKMLPHE_00845 1.14e-66 deoR - - K ko:K05346 - ko00000,ko03000 sugar-binding domain protein
EMKMLPHE_00846 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
EMKMLPHE_00847 1.25e-97 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
EMKMLPHE_00848 7.36e-308 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
EMKMLPHE_00849 7.59e-269 yttB - - EGP - - - Major Facilitator
EMKMLPHE_00850 7.71e-81 - - - - - - - -
EMKMLPHE_00851 1.46e-207 - - - S - - - Polyphosphate nucleotide phosphotransferase, PPK2 family
EMKMLPHE_00852 8.32e-47 - - - S - - - Fic/DOC family
EMKMLPHE_00853 2.09e-90 - - - S - - - Fic/DOC family
EMKMLPHE_00855 6.3e-95 - - - K ko:K18909 - ko00000,ko00002,ko01504,ko03000 helix_turn_helix multiple antibiotic resistance protein
EMKMLPHE_00856 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
EMKMLPHE_00858 1.29e-168 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
EMKMLPHE_00859 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EMKMLPHE_00860 1.09e-311 yycH - - S - - - YycH protein
EMKMLPHE_00861 1.18e-191 yycI - - S - - - YycH protein
EMKMLPHE_00862 2.52e-196 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
EMKMLPHE_00863 7.23e-284 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
EMKMLPHE_00864 9.62e-116 pgpA - - I - - - Phosphatidylglycerophosphatase A
EMKMLPHE_00865 4.26e-225 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
EMKMLPHE_00866 2.63e-115 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EMKMLPHE_00868 1.56e-125 - - - S - - - reductase
EMKMLPHE_00869 1.08e-288 dhaT 1.1.1.202 - C ko:K00086 ko00561,ko00640,map00561,map00640 ko00000,ko00001,ko01000 Dehydrogenase
EMKMLPHE_00870 1.7e-199 - - - U ko:K05340 - ko00000,ko02000 sugar transport
EMKMLPHE_00871 1.52e-192 - - - E - - - Glyoxalase-like domain
EMKMLPHE_00872 3.54e-188 - 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EMKMLPHE_00873 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
EMKMLPHE_00874 3.2e-197 hlyD3 - - M ko:K02005 - ko00000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EMKMLPHE_00875 3.99e-166 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
EMKMLPHE_00876 7.58e-270 - - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
EMKMLPHE_00877 3.39e-86 - - - M - - - Rib/alpha-like repeat
EMKMLPHE_00879 3.83e-70 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
EMKMLPHE_00880 4.75e-240 - - - L ko:K07484 - ko00000 Transposase IS66 family
EMKMLPHE_00881 3.39e-92 - - - L - - - An automated process has identified a potential problem with this gene model
EMKMLPHE_00882 6.69e-304 - - - L - - - Integrase core domain
EMKMLPHE_00883 1.44e-170 - - - O - - - Bacterial dnaA protein
EMKMLPHE_00889 2.61e-148 dgk2 - - F - - - deoxynucleoside kinase
EMKMLPHE_00890 0.0 lysP - - E ko:K03293,ko:K11733 - ko00000,ko02000 amino acid
EMKMLPHE_00891 1.68e-06 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
EMKMLPHE_00892 3.13e-150 - - - I - - - phosphatase
EMKMLPHE_00893 8.68e-106 - - - S - - - Threonine/Serine exporter, ThrE
EMKMLPHE_00894 2.85e-164 - - - S - - - Putative threonine/serine exporter
EMKMLPHE_00895 2.54e-42 cspC - - K ko:K03704 - ko00000,ko03000 Cold shock protein
EMKMLPHE_00896 3.16e-159 mntR - - K ko:K03709 - ko00000,ko03000 iron dependent repressor
EMKMLPHE_00897 1.58e-209 - - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
EMKMLPHE_00898 2.99e-151 - - - S - - - membrane
EMKMLPHE_00899 7.81e-141 - - - S - - - VIT family
EMKMLPHE_00900 4.83e-108 - - - T - - - Belongs to the universal stress protein A family
EMKMLPHE_00901 1.39e-173 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
EMKMLPHE_00902 3.85e-195 peb1A - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
EMKMLPHE_00903 5.24e-143 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
EMKMLPHE_00904 1.48e-140 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
EMKMLPHE_00905 8.11e-282 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
EMKMLPHE_00906 5.09e-302 - - - L - - - Transposase
EMKMLPHE_00907 4.48e-90 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
EMKMLPHE_00908 3.35e-59 - - - S - - - Pfam:DUF59
EMKMLPHE_00909 8.08e-216 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EMKMLPHE_00910 1.52e-119 - - - L - - - Integrase
EMKMLPHE_00912 3e-37 - - - - - - - -
EMKMLPHE_00913 9.55e-43 - - - S - - - Protein of unknown function (DUF2089)
EMKMLPHE_00914 1.34e-15 - - - LV - - - site-specific DNA-methyltransferase (adenine-specific) activity
EMKMLPHE_00915 9.85e-13 - - - - - - - -
EMKMLPHE_00916 2.56e-81 - - - S - - - Initiator Replication protein
EMKMLPHE_00921 3.39e-92 - - - L - - - An automated process has identified a potential problem with this gene model
EMKMLPHE_00922 4.75e-240 - - - L ko:K07484 - ko00000 Transposase IS66 family
EMKMLPHE_00923 3.83e-70 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
EMKMLPHE_00925 9.73e-112 - - - L - - - Transposase and inactivated derivatives, IS30 family
EMKMLPHE_00926 1.27e-24 - - - K - - - Cro/C1-type HTH DNA-binding domain
EMKMLPHE_00927 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
EMKMLPHE_00928 6.21e-241 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EMKMLPHE_00929 1.87e-217 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EMKMLPHE_00930 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EMKMLPHE_00931 8.67e-124 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
EMKMLPHE_00932 0.0 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
EMKMLPHE_00933 5.75e-103 yabR - - J ko:K07571 - ko00000 RNA binding
EMKMLPHE_00934 1.02e-74 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
EMKMLPHE_00935 1.01e-52 yabO - - J - - - S4 domain protein
EMKMLPHE_00936 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EMKMLPHE_00937 1.13e-131 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
EMKMLPHE_00938 3.29e-146 - - - S - - - (CBS) domain
EMKMLPHE_00939 8.04e-186 mhpD - - Q ko:K02509 ko00350,ko01120,map00350,map01120 ko00000,ko00001,ko01000 hydratase
EMKMLPHE_00940 9.21e-308 codA 3.5.4.1 - F ko:K01485 ko00240,ko00330,ko01100,map00240,map00330,map01100 ko00000,ko00001,ko01000 cytosine deaminase
EMKMLPHE_00941 0.0 - - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
EMKMLPHE_00942 5.31e-82 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
EMKMLPHE_00943 4.93e-266 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EMKMLPHE_00944 1.55e-79 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
EMKMLPHE_00945 4.54e-09 dltX - - S - - - D-Ala-teichoic acid biosynthesis protein
EMKMLPHE_00946 0.0 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EMKMLPHE_00947 1.29e-299 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
EMKMLPHE_00948 1e-47 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EMKMLPHE_00949 0.0 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EMKMLPHE_00950 1.34e-174 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
EMKMLPHE_00951 3.7e-19 - - - - - - - -
EMKMLPHE_00952 1.79e-266 thiP - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
EMKMLPHE_00953 1.67e-119 ltrA - - S - - - Bacterial low temperature requirement A protein (LtrA)
EMKMLPHE_00954 4.89e-122 - - - K - - - PFAM GCN5-related N-acetyltransferase
EMKMLPHE_00955 6.65e-104 - - - - - - - -
EMKMLPHE_00956 3.75e-175 - - - M - - - Lysin motif
EMKMLPHE_00957 4.24e-252 - - - EGP - - - Major Facilitator
EMKMLPHE_00958 2.74e-50 - - - D - - - Antitoxin component of a toxin-antitoxin (TA) module
EMKMLPHE_00959 1.38e-65 - - - S - - - ParE toxin of type II toxin-antitoxin system, parDE
EMKMLPHE_00960 1.25e-122 ywlG - - S - - - Belongs to the UPF0340 family
EMKMLPHE_00961 1.2e-205 - - - J - - - Methyltransferase
EMKMLPHE_00962 5.16e-289 oxlT - - P ko:K08177 - ko00000,ko02000 Major Facilitator Superfamily
EMKMLPHE_00963 4.25e-183 - - - V - - - DNA restriction-modification system
EMKMLPHE_00964 0.0 - - - G - - - Major Facilitator Superfamily
EMKMLPHE_00965 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
EMKMLPHE_00966 4.03e-208 add 3.5.4.2, 3.5.4.4 - F ko:K01488,ko:K21053 ko00230,ko01100,ko05340,map00230,map01100,map05340 ko00000,ko00001,ko01000 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EMKMLPHE_00967 1.64e-233 pbuG - - S ko:K06901 - ko00000,ko02000 permease
EMKMLPHE_00968 0.0 ade - - F - - - Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EMKMLPHE_00969 2.82e-98 - - - L - - - Helix-turn-helix domain
EMKMLPHE_00970 7.27e-190 - - - S ko:K06889 - ko00000 Hydrolases of the alpha beta superfamily
EMKMLPHE_00971 2.56e-249 adhP 1.1.1.1 - C ko:K00001,ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
EMKMLPHE_00972 2.81e-101 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
EMKMLPHE_00973 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
EMKMLPHE_00974 8.51e-143 - - - K - - - Bacterial regulatory proteins, tetR family
EMKMLPHE_00975 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EMKMLPHE_00976 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EMKMLPHE_00977 5.24e-260 - - - - - - - -
EMKMLPHE_00978 8.83e-141 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 Type II secretory pathway prepilin signal peptidase PulO and related peptidases
EMKMLPHE_00979 2.51e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EMKMLPHE_00980 2.06e-108 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
EMKMLPHE_00981 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EMKMLPHE_00982 1.28e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
EMKMLPHE_00983 5.45e-153 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EMKMLPHE_00984 6.64e-139 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
EMKMLPHE_00985 3.61e-61 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
EMKMLPHE_00986 1.16e-203 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EMKMLPHE_00987 5.72e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EMKMLPHE_00988 4.36e-70 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EMKMLPHE_00989 9.81e-157 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EMKMLPHE_00990 1.96e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EMKMLPHE_00991 5.49e-38 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
EMKMLPHE_00992 1.1e-55 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EMKMLPHE_00993 3.62e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EMKMLPHE_00994 2.58e-65 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EMKMLPHE_00995 7.42e-125 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EMKMLPHE_00996 4.97e-40 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EMKMLPHE_00997 1.54e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EMKMLPHE_00998 2.14e-123 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EMKMLPHE_00999 5.03e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EMKMLPHE_01000 3.45e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EMKMLPHE_01001 5.94e-34 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
EMKMLPHE_01002 8.6e-93 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
EMKMLPHE_01003 9.61e-305 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
EMKMLPHE_01004 6.16e-159 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
EMKMLPHE_01005 2.41e-45 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EMKMLPHE_01006 5.79e-21 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
EMKMLPHE_01007 2.19e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EMKMLPHE_01008 1.62e-83 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EMKMLPHE_01009 2.19e-220 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EMKMLPHE_01010 8.08e-83 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
EMKMLPHE_01011 1.71e-177 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EMKMLPHE_01012 3.12e-193 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EMKMLPHE_01013 6.79e-180 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EMKMLPHE_01014 1.75e-181 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
EMKMLPHE_01015 9.25e-103 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EMKMLPHE_01016 1.61e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
EMKMLPHE_01018 3.83e-70 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
EMKMLPHE_01019 4.75e-240 - - - L ko:K07484 - ko00000 Transposase IS66 family
EMKMLPHE_01020 3.39e-92 - - - L - - - An automated process has identified a potential problem with this gene model
EMKMLPHE_01021 4.49e-205 qor 1.1.1.1, 1.6.5.5 - C ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
EMKMLPHE_01022 5e-59 ydeP - - K - - - Transcriptional regulator, HxlR family
EMKMLPHE_01023 8.55e-06 - - - - - - - -
EMKMLPHE_01024 6.23e-10 - - - K - - - Cro/C1-type HTH DNA-binding domain
EMKMLPHE_01025 1.97e-54 - - - D - - - nuclear chromosome segregation
EMKMLPHE_01031 5.22e-101 tnpR1 - - L - - - Resolvase, N terminal domain
EMKMLPHE_01032 9.38e-39 - - - S - - - FRG
EMKMLPHE_01033 1.21e-28 - - - K - - - sequence-specific DNA binding
EMKMLPHE_01034 0.0 - - - J - - - Elongation factor G, domain IV
EMKMLPHE_01035 2.23e-113 allC 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 Peptidase family M20/M25/M40
EMKMLPHE_01038 1.12e-150 - - - - - - - -
EMKMLPHE_01041 1.45e-26 - - - S - - - Excisionase from transposon Tn916
EMKMLPHE_01042 2.66e-214 int7 - - L - - - Belongs to the 'phage' integrase family
EMKMLPHE_01043 6.04e-109 - - - - - - - -
EMKMLPHE_01044 8.01e-232 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
EMKMLPHE_01045 1.92e-67 - - - L ko:K07491 - ko00000 Transposase IS200 like
EMKMLPHE_01046 0.0 - 2.4.1.5 GH13 G ko:K00689 ko00500,ko02020,map00500,map02020 ko00000,ko00001,ko01000 Glycosyl hydrolase family 70
EMKMLPHE_01047 1.83e-21 - - - - - - - -
EMKMLPHE_01049 1.59e-217 whiA - - K ko:K09762 - ko00000 May be required for sporulation
EMKMLPHE_01050 9.5e-238 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
EMKMLPHE_01051 1.39e-208 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
EMKMLPHE_01052 3.66e-314 steT - - E ko:K03294 - ko00000 amino acid
EMKMLPHE_01053 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
EMKMLPHE_01054 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
EMKMLPHE_01055 1.03e-19 - - - - - - - -
EMKMLPHE_01056 1.45e-149 yfbR - - S ko:K07023 - ko00000 HD containing hydrolase-like enzyme
EMKMLPHE_01057 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
EMKMLPHE_01058 9.93e-115 ykhA 3.1.2.20 - I ko:K01073 - ko00000,ko01000 Thioesterase superfamily
EMKMLPHE_01059 2e-206 - - - ET ko:K02030 - ko00000,ko00002,ko02000 PFAM extracellular solute-binding protein, family 3
EMKMLPHE_01060 1.06e-258 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
EMKMLPHE_01061 3.39e-92 - - - L - - - An automated process has identified a potential problem with this gene model
EMKMLPHE_01062 4.75e-240 - - - L ko:K07484 - ko00000 Transposase IS66 family
EMKMLPHE_01063 3.83e-70 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
EMKMLPHE_01065 0.0 - - - G - - - Peptidase_C39 like family
EMKMLPHE_01066 2.54e-45 - - - - - - - -
EMKMLPHE_01067 4.12e-277 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
EMKMLPHE_01068 2.42e-265 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
EMKMLPHE_01069 4.89e-94 - - - M - - - transferase activity, transferring glycosyl groups
EMKMLPHE_01070 2.69e-109 - - - - - - - -
EMKMLPHE_01071 9.63e-38 - - - M - - - biosynthesis protein
EMKMLPHE_01072 1.1e-95 - - GT2 M ko:K12997 - ko00000,ko01000,ko01003,ko01005 Glycosyl transferase family 2
EMKMLPHE_01073 4.46e-84 - - - S - - - Glycosyltransferase like family
EMKMLPHE_01074 4.99e-98 - - - S ko:K07011 - ko00000 Glycosyltransferase, group 2 family protein
EMKMLPHE_01075 5e-88 - - - S - - - Acyltransferase family
EMKMLPHE_01077 3.83e-70 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
EMKMLPHE_01078 4.75e-240 - - - L ko:K07484 - ko00000 Transposase IS66 family
EMKMLPHE_01079 3.39e-92 - - - L - - - An automated process has identified a potential problem with this gene model
EMKMLPHE_01080 5.14e-92 - - - L - - - Helix-turn-helix domain
EMKMLPHE_01081 1.33e-173 - - - L ko:K07497 - ko00000 hmm pf00665
EMKMLPHE_01082 0.0 gtf2 - - M - - - A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
EMKMLPHE_01083 0.0 gtf1 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
EMKMLPHE_01085 3.83e-70 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
EMKMLPHE_01086 4.75e-240 - - - L ko:K07484 - ko00000 Transposase IS66 family
EMKMLPHE_01087 3.39e-92 - - - L - - - An automated process has identified a potential problem with this gene model
EMKMLPHE_01089 1.58e-70 - - - - - - - -
EMKMLPHE_01090 5.83e-152 yrkL - - S - - - Flavodoxin-like fold
EMKMLPHE_01092 2.01e-84 yeaO - - S - - - Protein of unknown function, DUF488
EMKMLPHE_01093 7.83e-153 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
EMKMLPHE_01094 1.02e-261 - - - S - - - associated with various cellular activities
EMKMLPHE_01095 9.52e-301 - - - S - - - Putative metallopeptidase domain
EMKMLPHE_01096 8.55e-64 - - - - - - - -
EMKMLPHE_01097 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
EMKMLPHE_01098 9.1e-139 - - - K - - - Helix-turn-helix XRE-family like proteins
EMKMLPHE_01099 8.54e-113 ymdB - - S - - - Macro domain protein
EMKMLPHE_01100 4.05e-250 - - - EGP - - - Major Facilitator
EMKMLPHE_01101 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EMKMLPHE_01102 7.86e-13 - - - K - - - helix_turn_helix, mercury resistance
EMKMLPHE_01103 8.81e-212 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
EMKMLPHE_01104 3.87e-199 metA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
EMKMLPHE_01105 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
EMKMLPHE_01106 1.67e-172 XK27_05695 - - V ko:K02003,ko:K19083 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
EMKMLPHE_01107 1.39e-229 kinG - - T - - - Histidine kinase-like ATPases
EMKMLPHE_01108 1.06e-161 XK27_10500 - - K - - - response regulator
EMKMLPHE_01109 8.44e-201 yvgN - - S - - - Aldo keto reductase
EMKMLPHE_01110 3.13e-172 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
EMKMLPHE_01111 1.59e-105 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
EMKMLPHE_01112 3.04e-259 - - - - - - - -
EMKMLPHE_01113 1.76e-68 - - - - - - - -
EMKMLPHE_01114 1.21e-48 - - - - - - - -
EMKMLPHE_01115 9.57e-47 - - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
EMKMLPHE_01116 1.15e-17 - - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
EMKMLPHE_01117 1.06e-184 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
EMKMLPHE_01118 4.27e-224 celE3 - - E - - - GDSL-like Lipase/Acylhydrolase family
EMKMLPHE_01119 4.92e-286 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EMKMLPHE_01120 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
EMKMLPHE_01121 9.37e-230 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
EMKMLPHE_01122 5.14e-92 - - - L - - - Helix-turn-helix domain
EMKMLPHE_01123 0.0 uvrA2 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 excinuclease ABC, A subunit
EMKMLPHE_01124 1.73e-70 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EMKMLPHE_01125 4.18e-75 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EMKMLPHE_01126 1.96e-89 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EMKMLPHE_01127 5.2e-186 - - - S - - - DUF218 domain
EMKMLPHE_01128 0.0 ubiB - - S ko:K03688 - ko00000 ABC1 family
EMKMLPHE_01129 2.2e-315 yhdP - - S - - - Transporter associated domain
EMKMLPHE_01130 3.97e-97 atkY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor CopY TcrY
EMKMLPHE_01131 3.5e-294 - - - U - - - Belongs to the major facilitator superfamily
EMKMLPHE_01132 2.93e-92 - - - S - - - UPF0756 membrane protein
EMKMLPHE_01133 9.06e-99 - - - S - - - Cupin domain
EMKMLPHE_01134 3.85e-66 - - - C - - - Flavodoxin
EMKMLPHE_01135 3.19e-187 rlrB - - K - - - LysR substrate binding domain protein
EMKMLPHE_01136 9.51e-88 - - - K - - - Bacterial transcriptional regulator
EMKMLPHE_01137 2.77e-165 kduD 1.1.1.127 - IQ ko:K00065 ko00040,map00040 ko00000,ko00001,ko01000 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EMKMLPHE_01138 3.14e-174 kduI 5.3.1.17 - G ko:K01815 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
EMKMLPHE_01139 2.95e-49 - - - G - - - Xylose isomerase-like TIM barrel
EMKMLPHE_01140 3.18e-14 - - - K ko:K21498 - ko00000,ko02048 Helix-turn-helix XRE-family like proteins
EMKMLPHE_01141 3.95e-19 - - - K ko:K21498 - ko00000,ko02048 Helix-turn-helix XRE-family like proteins
EMKMLPHE_01142 5.71e-276 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
EMKMLPHE_01143 6.81e-275 uxuT - - G ko:K03292,ko:K16210 - ko00000,ko02000 MFS/sugar transport protein
EMKMLPHE_01144 6.75e-230 uxuA 4.2.1.8 - G ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of D-mannonate
EMKMLPHE_01145 4.07e-262 uxuB 1.1.1.57 - G ko:K00040 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Mannitol dehydrogenase C-terminal domain
EMKMLPHE_01146 1.52e-67 kdgR - - K - - - FCD domain
EMKMLPHE_01147 1.05e-157 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 pfkB family carbohydrate kinase
EMKMLPHE_01148 2.08e-208 uxaA 4.2.1.7 - G ko:K01685 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
EMKMLPHE_01149 4.55e-89 eda 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 KDPG and KHG aldolase
EMKMLPHE_01150 9.05e-112 yqhA - - G - - - Aldose 1-epimerase
EMKMLPHE_01151 3.74e-152 uxaA 4.2.1.7 - G ko:K01685 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
EMKMLPHE_01152 6.44e-186 uxaB 1.1.1.58 - G ko:K00041 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 tagaturonate reductase activity
EMKMLPHE_01154 3.08e-120 - - - S - - - module of peptide synthetase
EMKMLPHE_01155 3.41e-290 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
EMKMLPHE_01156 4.89e-279 - - - G ko:K03292 - ko00000 MFS/sugar transport protein
EMKMLPHE_01157 1.63e-118 exuR - - K ko:K02529 - ko00000,ko03000 Periplasmic binding protein domain
EMKMLPHE_01158 2.76e-214 yvgN - - C - - - Aldo keto reductase
EMKMLPHE_01159 1.02e-51 XK27_08630 - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
EMKMLPHE_01160 4.27e-308 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
EMKMLPHE_01161 7.5e-122 - - - K - - - Acetyltransferase (GNAT) domain
EMKMLPHE_01162 5.06e-198 - - - S - - - Alpha beta hydrolase
EMKMLPHE_01163 4.69e-199 gspA - - M - - - family 8
EMKMLPHE_01164 2.4e-151 yagB - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
EMKMLPHE_01165 2.28e-118 - - - - - - - -
EMKMLPHE_01166 1.64e-204 - - - S - - - EDD domain protein, DegV family
EMKMLPHE_01167 1.1e-205 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
EMKMLPHE_01168 3.99e-72 ltrA - - S - - - Bacterial low temperature requirement A protein (LtrA)
EMKMLPHE_01169 5.26e-55 ltrA - - S - - - Bacterial low temperature requirement A protein (LtrA)
EMKMLPHE_01170 2.71e-103 usp5 - - T - - - universal stress protein
EMKMLPHE_01171 2.7e-104 - - - K ko:K03719 - ko00000,ko03000,ko03036 AsnC family
EMKMLPHE_01172 5.61e-292 gltT - - U ko:K03309,ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
EMKMLPHE_01173 2.6e-141 apl 3.1.3.1 - S ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 SNARE associated Golgi protein
EMKMLPHE_01174 5.78e-39 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix domain
EMKMLPHE_01175 3.12e-130 - - - S - - - Protein of unknown function (DUF3278)
EMKMLPHE_01177 1.46e-156 - - - M - - - PFAM NLP P60 protein
EMKMLPHE_01178 7.44e-232 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
EMKMLPHE_01179 1.18e-196 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
EMKMLPHE_01180 5.63e-177 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EMKMLPHE_01181 2.98e-123 - - - P - - - Cadmium resistance transporter
EMKMLPHE_01182 4.63e-74 czrA - - K ko:K22043 - ko00000,ko03000 Transcriptional regulator, ArsR family
EMKMLPHE_01183 4.19e-300 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
EMKMLPHE_01184 6.46e-74 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
EMKMLPHE_01185 1.08e-168 yceF - - P ko:K05794 - ko00000 membrane
EMKMLPHE_01186 8.51e-214 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
EMKMLPHE_01187 3.34e-215 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
EMKMLPHE_01188 0.0 pepD1 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
EMKMLPHE_01189 2.77e-306 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
EMKMLPHE_01190 1.56e-312 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
EMKMLPHE_01191 4.5e-288 - - - S - - - C4-dicarboxylate anaerobic carrier
EMKMLPHE_01192 1.44e-170 - - - O - - - Bacterial dnaA protein
EMKMLPHE_01193 6.69e-304 - - - L - - - Integrase core domain
EMKMLPHE_01194 6.36e-75 - - - - - - - -
EMKMLPHE_01195 2.71e-51 - - - S - - - Protein of unknown function (DUF1797)
EMKMLPHE_01196 9.33e-229 mprF - - I ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EMKMLPHE_01197 1.13e-252 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
EMKMLPHE_01198 8.93e-291 pimB 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
EMKMLPHE_01199 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EMKMLPHE_01200 3.69e-54 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
EMKMLPHE_01201 5.62e-37 - - - - - - - -
EMKMLPHE_01202 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
EMKMLPHE_01203 1.56e-130 - - - S - - - Pfam:DUF3816
EMKMLPHE_01204 5.49e-182 - - - G - - - MucBP domain
EMKMLPHE_01205 1.17e-147 - - - - - - - -
EMKMLPHE_01206 2.92e-198 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EMKMLPHE_01207 1.19e-84 - - - K - - - Transcriptional regulator, GntR family
EMKMLPHE_01208 0.0 bamA - - GM ko:K07277,ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko02000,ko03016,ko03019,ko03029 domain, Protein
EMKMLPHE_01209 0.0 - - - S - - - Peptidase, M23
EMKMLPHE_01210 0.0 - - - M - - - NlpC/P60 family
EMKMLPHE_01211 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EMKMLPHE_01212 2.39e-301 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
EMKMLPHE_01213 3.74e-232 yueF - - S - - - AI-2E family transporter
EMKMLPHE_01214 0.0 csd1 3.5.1.28 - M ko:K01447,ko:K17733,ko:K19117 - ko00000,ko01000,ko01002,ko01011,ko02048 N-Acetylmuramoyl-L-alanine amidase
EMKMLPHE_01215 3.8e-63 - - - - - - - -
EMKMLPHE_01216 1.81e-41 - - - - - - - -
EMKMLPHE_01217 7.29e-60 - - - - - - - -
EMKMLPHE_01218 3.04e-56 - - - S - - - Protein of unknown function (DUF805)
EMKMLPHE_01219 3.09e-19 - - - IQ - - - KR domain
EMKMLPHE_01220 0.0 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
EMKMLPHE_01221 1.01e-247 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
EMKMLPHE_01222 6.18e-76 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 type I restriction modification DNA specificity domain protein
EMKMLPHE_01223 1.02e-228 - - - L - - - Belongs to the 'phage' integrase family
EMKMLPHE_01224 1.18e-76 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
EMKMLPHE_01225 0.0 - - - L - - - PLD-like domain
EMKMLPHE_01227 3.68e-228 rihA - - F ko:K01250 - ko00000,ko01000 Inosine-uridine preferring nucleoside hydrolase
EMKMLPHE_01228 4.62e-232 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EMKMLPHE_01229 1.96e-123 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
EMKMLPHE_01230 1.86e-286 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
EMKMLPHE_01231 4.52e-101 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
EMKMLPHE_01232 1.87e-65 - - - T ko:K10716 - ko00000,ko02000 Ion transport 2 domain protein
EMKMLPHE_01233 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
EMKMLPHE_01234 8.99e-258 - - - G - - - Transporter, major facilitator family protein
EMKMLPHE_01235 1.87e-137 yvrI - - K ko:K03091,ko:K03093 - ko00000,ko03021 sigma factor activity
EMKMLPHE_01236 2.08e-79 yuxO - - Q - - - Thioesterase superfamily
EMKMLPHE_01237 1.16e-199 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EMKMLPHE_01238 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
EMKMLPHE_01239 0.0 feoB - - P ko:K04759 - ko00000,ko02000 transporter of a GTP-driven Fe(2 ) uptake system
EMKMLPHE_01240 6.71e-41 feoA - - P ko:K04758 - ko00000,ko02000 FeoA domain
EMKMLPHE_01241 1.56e-184 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
EMKMLPHE_01242 2.36e-305 sufD - - O ko:K07033,ko:K09015 - ko00000 FeS assembly protein SufD
EMKMLPHE_01243 8.34e-295 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EMKMLPHE_01244 1.24e-103 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
EMKMLPHE_01245 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
EMKMLPHE_01246 1.18e-76 - - - S - - - Iron-sulfur cluster assembly protein
EMKMLPHE_01247 6.4e-204 - - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
EMKMLPHE_01248 1.18e-146 nreC - - K ko:K07696 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 PFAM regulatory protein LuxR
EMKMLPHE_01249 1.43e-51 - - - S - - - Cytochrome B5
EMKMLPHE_01250 3.3e-198 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
EMKMLPHE_01251 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
EMKMLPHE_01252 1.8e-190 - - - O - - - Band 7 protein
EMKMLPHE_01253 7.5e-56 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 LytS YhcK-type transmembrane receptor domain protein
EMKMLPHE_01254 4.96e-222 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
EMKMLPHE_01255 7.04e-215 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
EMKMLPHE_01256 9.1e-237 galR - - K ko:K02529 - ko00000,ko03000 Periplasmic binding protein-like domain
EMKMLPHE_01257 0.0 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
EMKMLPHE_01258 0.0 - - - L - - - Transposase
EMKMLPHE_01259 0.0 - - - L - - - PFAM RNA-directed DNA polymerase (Reverse transcriptase)
EMKMLPHE_01260 1.13e-117 - - - S ko:K08996 - ko00000 Protein of unknown function (DUF1440)
EMKMLPHE_01261 3.63e-247 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
EMKMLPHE_01262 1.13e-271 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
EMKMLPHE_01263 8.5e-218 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
EMKMLPHE_01264 2.86e-217 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 mevalonate kinase
EMKMLPHE_01265 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
EMKMLPHE_01266 1.57e-113 ypmB - - S - - - Protein conserved in bacteria
EMKMLPHE_01267 7.96e-158 dnaD - - L ko:K02086 - ko00000 DnaD domain protein
EMKMLPHE_01268 2.32e-206 - - - EG - - - EamA-like transporter family
EMKMLPHE_01269 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
EMKMLPHE_01270 2.01e-152 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
EMKMLPHE_01271 5.6e-129 ypsA - - S - - - Belongs to the UPF0398 family
EMKMLPHE_01272 3.25e-72 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
EMKMLPHE_01273 6.59e-106 - - - F ko:K03647 - ko00000 Belongs to the NrdI family
EMKMLPHE_01274 1.7e-282 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
EMKMLPHE_01275 1.55e-91 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease HI
EMKMLPHE_01276 7.39e-85 esbA - - S - - - Family of unknown function (DUF5322)
EMKMLPHE_01277 1.26e-96 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EMKMLPHE_01278 3.24e-221 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
EMKMLPHE_01279 5.29e-263 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarA family
EMKMLPHE_01280 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
EMKMLPHE_01281 0.0 FbpA - - K - - - Fibronectin-binding protein
EMKMLPHE_01282 2.27e-74 - - - L - - - PFAM RNA-directed DNA polymerase (Reverse transcriptase)
EMKMLPHE_01283 2.23e-124 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
EMKMLPHE_01284 7.72e-279 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
EMKMLPHE_01285 5.4e-63 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein
EMKMLPHE_01286 6.68e-156 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EMKMLPHE_01287 4.03e-143 yqeK - - H - - - Hydrolase, HD family
EMKMLPHE_01288 1.9e-79 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
EMKMLPHE_01289 8.35e-175 yqeM - - Q - - - Methyltransferase
EMKMLPHE_01290 1.21e-267 ylbM - - S - - - Belongs to the UPF0348 family
EMKMLPHE_01291 1.01e-129 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
EMKMLPHE_01292 7.21e-39 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
EMKMLPHE_01293 1.38e-155 csrR - - K - - - response regulator
EMKMLPHE_01294 0.0 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EMKMLPHE_01295 0.0 potE - - E - - - Amino Acid
EMKMLPHE_01296 1.02e-295 - - - V - - - MatE
EMKMLPHE_01297 1.52e-89 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
EMKMLPHE_01298 2.25e-214 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EMKMLPHE_01299 2.36e-56 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
EMKMLPHE_01300 1.1e-185 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EMKMLPHE_01301 2.17e-118 XK27_09705 - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
EMKMLPHE_01302 1.37e-76 yodB - - K - - - Transcriptional regulator, HxlR family
EMKMLPHE_01303 3.66e-252 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EMKMLPHE_01304 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
EMKMLPHE_01305 1.9e-145 - - - M - - - PFAM NLP P60 protein
EMKMLPHE_01306 2.8e-150 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
EMKMLPHE_01307 3.52e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
EMKMLPHE_01308 2.13e-88 yneR - - S - - - Belongs to the HesB IscA family
EMKMLPHE_01309 0.0 - - - S - - - membrane
EMKMLPHE_01310 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
EMKMLPHE_01311 1.53e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
EMKMLPHE_01312 1.38e-131 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EMKMLPHE_01313 5.07e-96 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Peptidase, S54 family
EMKMLPHE_01314 1.76e-26 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Peptidase, S54 family
EMKMLPHE_01315 7.07e-48 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
EMKMLPHE_01316 1.02e-234 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
EMKMLPHE_01317 1.09e-87 yqhL - - P - - - Rhodanese-like protein
EMKMLPHE_01318 2.39e-30 - - - S - - - Protein of unknown function (DUF3042)
EMKMLPHE_01319 1.13e-223 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EMKMLPHE_01320 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
EMKMLPHE_01321 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EMKMLPHE_01322 1.46e-118 araT 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
EMKMLPHE_01323 7.46e-41 araT 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
EMKMLPHE_01324 5.49e-52 araT 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
EMKMLPHE_01325 6.49e-228 - - - L - - - Transposase DDE domain
EMKMLPHE_01326 2.94e-72 - - - - - - - -
EMKMLPHE_01327 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EMKMLPHE_01329 3.95e-07 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 Vacuole effluxer Atg22 like
EMKMLPHE_01330 9.44e-94 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 Vacuole effluxer Atg22 like
EMKMLPHE_01331 3.49e-106 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 Vacuole effluxer Atg22 like
EMKMLPHE_01332 2.2e-69 npp - - S - - - type I phosphodiesterase nucleotide pyrophosphatase
EMKMLPHE_01333 3.08e-77 npp - - S - - - type I phosphodiesterase nucleotide pyrophosphatase
EMKMLPHE_01334 1.37e-83 npp - - S - - - type I phosphodiesterase nucleotide pyrophosphatase
EMKMLPHE_01335 2.71e-39 npp - - S - - - type I phosphodiesterase nucleotide pyrophosphatase
EMKMLPHE_01336 4.67e-313 - - - E ko:K03294 - ko00000 amino acid
EMKMLPHE_01337 9.04e-152 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EMKMLPHE_01338 8.95e-20 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EMKMLPHE_01340 8.37e-280 - 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
EMKMLPHE_01341 3.78e-20 - - - S - - - Cytochrome B5
EMKMLPHE_01342 4.97e-97 - - - S ko:K02348 - ko00000 Gnat family
EMKMLPHE_01343 1.11e-156 - - - GM - - - NmrA-like family
EMKMLPHE_01344 1.07e-66 ydeP - - K - - - Transcriptional regulator, HxlR family
EMKMLPHE_01345 7.53e-137 XK27_02070 - - S ko:K07078 - ko00000 Nitroreductase family
EMKMLPHE_01346 7.27e-106 - - - K - - - Transcriptional regulator, HxlR family
EMKMLPHE_01347 9.71e-293 - - - - - - - -
EMKMLPHE_01348 2.65e-269 - - - EGP - - - Major Facilitator Superfamily
EMKMLPHE_01349 0.0 pepE 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
EMKMLPHE_01350 8.37e-145 - - - GM - - - NAD dependent epimerase dehydratase family protein
EMKMLPHE_01351 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
EMKMLPHE_01352 9.75e-145 frnE 5.3.4.1 - Q ko:K01829 - ko00000,ko01000 DSBA-like thioredoxin domain
EMKMLPHE_01353 1.24e-209 - - - I - - - alpha/beta hydrolase fold
EMKMLPHE_01354 2.05e-27 - - - K - - - Helix-turn-helix XRE-family like proteins
EMKMLPHE_01355 4.22e-41 - - - S - - - Phage derived protein Gp49-like (DUF891)
EMKMLPHE_01356 1.39e-257 - - - M - - - hydrolase, family 25
EMKMLPHE_01357 3.67e-69 - - - S - - - Bacteriophage holin of superfamily 6 (Holin_LLH)
EMKMLPHE_01358 3.41e-47 - - - S - - - Bacteriophage holin family
EMKMLPHE_01362 7.94e-109 - - - S - - - Domain of unknown function (DUF2479)
EMKMLPHE_01364 0.0 spoIIQ - - M ko:K06386 - ko00000 Peptidase family M23
EMKMLPHE_01365 5.09e-202 - - - S - - - Phage tail protein
EMKMLPHE_01366 1.05e-110 - - - L - - - Phage tail tape measure protein TP901
EMKMLPHE_01367 1.58e-305 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
EMKMLPHE_01368 5.02e-190 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 biotin lipoate A B protein ligase
EMKMLPHE_01369 0.0 ywfO - - S ko:K06885 - ko00000 HD domain protein
EMKMLPHE_01370 7.71e-189 yidA - - S - - - hydrolase
EMKMLPHE_01371 1.19e-98 - - - - - - - -
EMKMLPHE_01372 3.53e-229 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EMKMLPHE_01373 3.04e-312 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EMKMLPHE_01374 2.09e-190 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
EMKMLPHE_01375 1.75e-165 - - - U ko:K02075 - ko00000,ko00002,ko02000 ABC 3 transport family
EMKMLPHE_01376 1.98e-157 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
EMKMLPHE_01377 1.93e-213 psaA - - P ko:K02077,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
EMKMLPHE_01378 1.71e-206 ispE 2.7.1.148 - F ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EMKMLPHE_01379 2.74e-50 veg - - S - - - Biofilm formation stimulator VEG
EMKMLPHE_01380 1.03e-205 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
EMKMLPHE_01381 7.04e-127 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EMKMLPHE_01382 3.58e-198 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
EMKMLPHE_01383 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EMKMLPHE_01384 3.2e-206 yunF - - F - - - Protein of unknown function DUF72
EMKMLPHE_01386 4.85e-167 cobB - - K ko:K12410 - ko00000,ko01000 SIR2 family
EMKMLPHE_01387 1.05e-225 - - - - - - - -
EMKMLPHE_01388 7.91e-288 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
EMKMLPHE_01389 2.53e-214 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
EMKMLPHE_01390 2.26e-242 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
EMKMLPHE_01391 8.74e-234 - 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 Belongs to the N(4) N(6)-methyltransferase family
EMKMLPHE_01392 4.08e-106 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Belongs to the NDK family
EMKMLPHE_01393 0.0 - - - L - - - DNA helicase
EMKMLPHE_01394 7.77e-261 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
EMKMLPHE_01396 0.0 gabT 2.6.1.19, 5.1.1.21 - E ko:K00823,ko:K20708 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EMKMLPHE_01397 0.0 ctrA - - E ko:K03294 - ko00000 amino acid
EMKMLPHE_01398 1.64e-151 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EMKMLPHE_01399 5.74e-54 - 1.3.5.4 - S ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FMN binding
EMKMLPHE_01400 1.7e-280 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 transporter
EMKMLPHE_01401 7e-215 hdhL 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
EMKMLPHE_01402 5.91e-198 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
EMKMLPHE_01403 3.47e-244 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EMKMLPHE_01404 1.06e-139 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
EMKMLPHE_01405 6.29e-272 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
EMKMLPHE_01406 9.39e-238 eriC - - P ko:K03281 - ko00000 chloride
EMKMLPHE_01407 2.48e-274 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
EMKMLPHE_01408 1.12e-76 - - - L ko:K07491 - ko00000 PFAM transposase IS200-family protein
EMKMLPHE_01409 7.7e-104 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
EMKMLPHE_01410 1.32e-136 - - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, permease protein
EMKMLPHE_01411 3.69e-183 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
EMKMLPHE_01412 7.17e-135 proWZ - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
EMKMLPHE_01413 8.79e-208 proWY - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, QAT family
EMKMLPHE_01414 3.71e-95 ywnA - - K - - - Transcriptional regulator
EMKMLPHE_01415 2.68e-45 - - - GM - - - NAD(P)H-binding
EMKMLPHE_01416 4.44e-11 - - - - - - - -
EMKMLPHE_01417 1.4e-280 - 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Metalloenzyme superfamily
EMKMLPHE_01418 0.0 cadA - - P - - - P-type ATPase
EMKMLPHE_01419 1.53e-160 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
EMKMLPHE_01420 2.12e-162 - - - - - - - -
EMKMLPHE_01421 1.85e-69 - - - S - - - Sugar efflux transporter for intercellular exchange
EMKMLPHE_01422 7.42e-311 - 1.8.1.7 - C ko:K00383,ko:K21739 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Pyridine nucleotide-disulfide oxidoreductase
EMKMLPHE_01424 0.0 - - - L - - - Helicase C-terminal domain protein
EMKMLPHE_01425 2.43e-105 - 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 PAP2 superfamily
EMKMLPHE_01426 7.7e-227 ydhF - - S - - - Aldo keto reductase
EMKMLPHE_01428 5.03e-181 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
EMKMLPHE_01429 4.48e-37 psiE - - S ko:K13256 - ko00000 Phosphate-starvation-inducible E
EMKMLPHE_01430 3.28e-128 - - - S ko:K07002 - ko00000 Serine hydrolase
EMKMLPHE_01432 5.64e-232 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EMKMLPHE_01433 0.0 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
EMKMLPHE_01434 2.22e-50 - - - S - - - Cytochrome b5-like Heme/Steroid binding domain
EMKMLPHE_01435 9.4e-148 - - - S ko:K07118 - ko00000 NAD(P)H-binding
EMKMLPHE_01436 1.3e-48 - - - - - - - -
EMKMLPHE_01437 1.03e-24 - - - IQ - - - dehydrogenase reductase
EMKMLPHE_01438 2.98e-77 - - - IQ - - - dehydrogenase reductase
EMKMLPHE_01439 6.78e-306 - - - EGP - - - MFS transporter, metabolite H symporter (MHS) family protein
EMKMLPHE_01440 1.6e-19 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
EMKMLPHE_01441 6.21e-16 - - - M - - - Rib/alpha-like repeat
EMKMLPHE_01443 3.83e-70 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
EMKMLPHE_01444 4.75e-240 - - - L ko:K07484 - ko00000 Transposase IS66 family
EMKMLPHE_01445 3.39e-92 - - - L - - - An automated process has identified a potential problem with this gene model
EMKMLPHE_01446 5.44e-96 - - - - - - - -
EMKMLPHE_01447 4.52e-184 - - - M - - - Glycosyl transferase family 2
EMKMLPHE_01448 2.46e-173 - - - - - - - -
EMKMLPHE_01449 0.0 - - CBM50 NU ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
EMKMLPHE_01450 1.58e-205 rfbA 2.7.7.24 - H ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EMKMLPHE_01451 7.93e-140 rfbC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
EMKMLPHE_01452 1.15e-263 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
EMKMLPHE_01453 5.37e-221 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional regulator, LacI family
EMKMLPHE_01454 2.6e-33 - - - - - - - -
EMKMLPHE_01455 1.91e-142 - - - - - - - -
EMKMLPHE_01456 4.1e-272 yttB - - EGP - - - Major Facilitator
EMKMLPHE_01457 7.97e-311 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
EMKMLPHE_01458 6.5e-111 - - - - - - - -
EMKMLPHE_01459 1.68e-139 nnrE 5.1.99.6 - H ko:K17759 - ko00000,ko01000 Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
EMKMLPHE_01460 0.0 - - - S - - - Putative peptidoglycan binding domain
EMKMLPHE_01461 8.11e-159 - - - M - - - ErfK YbiS YcfS YnhG
EMKMLPHE_01463 8.47e-126 - - - - - - - -
EMKMLPHE_01464 4.45e-274 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
EMKMLPHE_01465 3.17e-106 - - - S - - - Alpha beta hydrolase
EMKMLPHE_01466 1.6e-49 - - - S - - - Alpha beta hydrolase
EMKMLPHE_01467 9.63e-103 - - - L - - - transposase IS116 IS110 IS902 family protein
EMKMLPHE_01468 3.84e-145 - - - L - - - transposase IS116 IS110 IS902 family protein
EMKMLPHE_01469 1.16e-263 gldA 1.1.1.6 - C ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 ko00000,ko00001,ko01000 dehydrogenase
EMKMLPHE_01470 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
EMKMLPHE_01471 1.7e-54 - - - - - - - -
EMKMLPHE_01472 9.5e-162 pgm3 - - G - - - phosphoglycerate mutase family
EMKMLPHE_01473 5.37e-45 - - - K - - - Bacterial transcriptional regulator
EMKMLPHE_01474 9.14e-89 - 1.1.1.100, 1.1.1.304, 1.1.1.76 - IQ ko:K00059,ko:K18009 ko00061,ko00333,ko00650,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00650,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
EMKMLPHE_01475 3.81e-41 - - - S - - - C4-dicarboxylate anaerobic carrier
EMKMLPHE_01476 6.69e-304 - - - L - - - Integrase core domain
EMKMLPHE_01477 1.44e-170 - - - O - - - Bacterial dnaA protein
EMKMLPHE_01479 3.83e-70 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
EMKMLPHE_01480 4.75e-240 - - - L ko:K07484 - ko00000 Transposase IS66 family
EMKMLPHE_01481 3.39e-92 - - - L - - - An automated process has identified a potential problem with this gene model
EMKMLPHE_01482 2.67e-215 tagE6 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
EMKMLPHE_01483 0.0 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Poly(Glycerol-phosphate) alpha-glucosyltransferase
EMKMLPHE_01484 0.0 sdrF - - M ko:K14194 ko05150,map05150 ko00000,ko00001 protein which possibly mediates interactions of S.aureus with components of the extracellular matrix of higher eukaryotes
EMKMLPHE_01485 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
EMKMLPHE_01486 0.0 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
EMKMLPHE_01487 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
EMKMLPHE_01488 8.13e-263 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
EMKMLPHE_01489 0.0 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
EMKMLPHE_01490 8.55e-226 cytR - - K ko:K02529,ko:K03604 - ko00000,ko03000 Transcriptional regulator, LacI family
EMKMLPHE_01491 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EMKMLPHE_01492 5.75e-130 - 1.5.1.36 - S ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 reductase
EMKMLPHE_01493 6.57e-262 - 1.5.1.36 - S ko:K19784,ko:K22393,ko:K22394 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 reductase
EMKMLPHE_01494 9.36e-224 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
EMKMLPHE_01495 1.05e-34 - - - L ko:K07491 - ko00000 PFAM transposase IS200-family protein
EMKMLPHE_01497 4.91e-44 - - - L - - - PFAM RNA-directed DNA polymerase (Reverse transcriptase)
EMKMLPHE_01498 0.0 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EMKMLPHE_01499 0.0 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
EMKMLPHE_01500 8.05e-178 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
EMKMLPHE_01501 2.51e-285 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
EMKMLPHE_01502 2.4e-278 nupG - - F ko:K03317,ko:K11535,ko:K16323 - ko00000,ko02000 Nucleoside transporter
EMKMLPHE_01503 4.78e-218 rihA 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
EMKMLPHE_01504 5.72e-206 - 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 3-hydroxyacyl-CoA dehydrogenase
EMKMLPHE_01505 9.18e-156 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
EMKMLPHE_01506 1.32e-193 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
EMKMLPHE_01507 8.34e-180 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
EMKMLPHE_01508 8e-197 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
EMKMLPHE_01509 2.37e-42 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
EMKMLPHE_01510 1.75e-254 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
EMKMLPHE_01511 6.3e-175 - - - S - - - Protein of unknown function (DUF1129)
EMKMLPHE_01512 9.74e-154 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EMKMLPHE_01513 4.64e-298 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
EMKMLPHE_01514 1.58e-300 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 pyrimidine-nucleoside phosphorylase
EMKMLPHE_01515 3.27e-167 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
EMKMLPHE_01516 3.92e-217 deoR - - K ko:K05346 - ko00000,ko03000 sugar-binding domain protein
EMKMLPHE_01517 1.47e-265 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
EMKMLPHE_01518 9.76e-161 vanR - - K - - - response regulator
EMKMLPHE_01519 3.73e-264 hpk31 - - T - - - Histidine kinase
EMKMLPHE_01520 9.75e-186 - - - E - - - AzlC protein
EMKMLPHE_01521 4.05e-70 - - - S - - - branched-chain amino acid
EMKMLPHE_01522 1.12e-165 - - - K - - - LysR substrate binding domain
EMKMLPHE_01523 2.57e-221 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
EMKMLPHE_01524 2.13e-313 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
EMKMLPHE_01525 1.87e-218 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
EMKMLPHE_01526 3.95e-167 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
EMKMLPHE_01527 1.51e-147 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EMKMLPHE_01528 3.7e-148 - - - S - - - Haloacid dehalogenase-like hydrolase
EMKMLPHE_01529 2.62e-122 ribB 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EMKMLPHE_01530 1.64e-291 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
EMKMLPHE_01531 3.86e-223 ydbI - - K - - - AI-2E family transporter
EMKMLPHE_01532 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
EMKMLPHE_01533 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
EMKMLPHE_01534 3.66e-165 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Belongs to the alpha-acetolactate decarboxylase family
EMKMLPHE_01535 5.74e-24 mocA - - S - - - Oxidoreductase
EMKMLPHE_01536 1.36e-30 rhaS4 - - K - - - helix_turn_helix, arabinose operon control protein
EMKMLPHE_01537 5.9e-231 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
EMKMLPHE_01538 3.61e-219 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
EMKMLPHE_01539 7.04e-127 thrB 2.7.1.39 - F ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
EMKMLPHE_01540 8.95e-110 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EMKMLPHE_01541 7.12e-275 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EMKMLPHE_01542 0.0 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EMKMLPHE_01543 3.53e-168 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
EMKMLPHE_01544 4.5e-50 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EMKMLPHE_01545 5.68e-163 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EMKMLPHE_01546 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EMKMLPHE_01547 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EMKMLPHE_01548 4.6e-249 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
EMKMLPHE_01549 2.37e-135 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EMKMLPHE_01550 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
EMKMLPHE_01551 9.62e-309 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
EMKMLPHE_01552 5.27e-169 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EMKMLPHE_01553 1.85e-225 - - - - - - - -
EMKMLPHE_01554 1.35e-302 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EMKMLPHE_01555 1.37e-71 - - - S - - - Uncharacterised protein family (UPF0236)
EMKMLPHE_01556 9.57e-52 - - - S - - - Uncharacterised protein family (UPF0236)
EMKMLPHE_01557 1.2e-42 - - - S - - - Cytochrome b5-like Heme/Steroid binding domain
EMKMLPHE_01558 2.25e-107 - - - M - - - LPXTG-motif cell wall anchor domain protein
EMKMLPHE_01559 1.37e-71 - - - S - - - Uncharacterised protein family (UPF0236)
EMKMLPHE_01560 9.57e-52 - - - S - - - Uncharacterised protein family (UPF0236)
EMKMLPHE_01561 5.68e-12 - - - IQ - - - KR domain
EMKMLPHE_01562 9.4e-146 - - - IQ - - - KR domain
EMKMLPHE_01563 1.47e-171 - - - S ko:K07090 - ko00000 membrane transporter protein
EMKMLPHE_01564 1.05e-127 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
EMKMLPHE_01565 3.61e-316 - - - S ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
EMKMLPHE_01566 4.63e-144 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
EMKMLPHE_01567 6.5e-71 - - - - - - - -
EMKMLPHE_01568 0.0 nhaK - - P ko:K03316 - ko00000 Sodium proton antiporter
EMKMLPHE_01569 2.59e-68 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
EMKMLPHE_01570 1.03e-240 ybcH - - D ko:K06889 - ko00000 Alpha beta
EMKMLPHE_01571 1.3e-95 - - - K - - - Transcriptional regulator
EMKMLPHE_01572 2.62e-202 - - - - - - - -
EMKMLPHE_01573 5.8e-223 - - - C - - - Zinc-binding dehydrogenase
EMKMLPHE_01574 0.0 - - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system Galactitol-specific IIC component
EMKMLPHE_01575 3.23e-269 - - - EGP - - - Major Facilitator
EMKMLPHE_01576 2.16e-173 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
EMKMLPHE_01577 1.3e-148 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
EMKMLPHE_01578 4.39e-11 - - - - - - - -
EMKMLPHE_01579 1.78e-83 - - - - - - - -
EMKMLPHE_01580 1.42e-248 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
EMKMLPHE_01581 7.46e-106 uspA3 - - T - - - universal stress protein
EMKMLPHE_01582 0.0 fusA1 - - J - - - elongation factor G
EMKMLPHE_01583 2.96e-211 - - - GK - - - ROK family
EMKMLPHE_01584 6.02e-305 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
EMKMLPHE_01585 3.54e-177 yfhR3 - - S ko:K06889 - ko00000 Serine hydrolase (FSH1)
EMKMLPHE_01586 7.37e-99 - - - E - - - amino acid
EMKMLPHE_01587 3.59e-147 - - - E - - - amino acid
EMKMLPHE_01588 7.66e-23 - - - E - - - amino acid
EMKMLPHE_01589 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
EMKMLPHE_01590 8.56e-162 gntR - - K - - - UbiC transcription regulator-associated domain protein
EMKMLPHE_01591 1.85e-110 ebsC - - J ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EMKMLPHE_01592 0.0 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
EMKMLPHE_01593 0.0 rtpR 1.17.4.2 - F ko:K00527 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 ribonucleoside-triphosphate reductase activity
EMKMLPHE_01594 0.0 yfiC - - V ko:K06147 - ko00000,ko02000 ABC transporter
EMKMLPHE_01595 0.0 ycfI - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
EMKMLPHE_01596 1.16e-23 - - - K - - - Winged helix-turn-helix DNA-binding
EMKMLPHE_01597 1.86e-227 ldhA 1.1.1.28 - C ko:K03778,ko:K18347 ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01504 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EMKMLPHE_01598 3.85e-24 - - - S - - - PFAM Archaeal ATPase
EMKMLPHE_01599 5.76e-103 - - - S ko:K16927 - ko00000,ko00002,ko02000 ECF transporter, substrate-specific component
EMKMLPHE_01600 5.84e-66 - - - S - - - Domain of unknown function (DUF4430)
EMKMLPHE_01601 3.21e-66 - - - EG - - - PFAM EamA-like transporter family
EMKMLPHE_01602 2.26e-185 cobT 2.4.2.21 - F ko:K00768 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)
EMKMLPHE_01603 1.1e-91 - - - H - - - Uroporphyrinogen-III synthase
EMKMLPHE_01604 4.47e-95 cobC 3.1.3.73 - G ko:K02226 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
EMKMLPHE_01605 2.56e-152 cobS 2.7.8.26 - H ko:K02233 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
EMKMLPHE_01606 1.41e-98 cobU 2.7.1.156, 2.7.7.62 - H ko:K02231 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Cobinamide kinase / cobinamide phosphate guanyltransferase
EMKMLPHE_01607 2.26e-304 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class-III
EMKMLPHE_01608 2.77e-223 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Delta-aminolevulinic acid dehydratase
EMKMLPHE_01609 4.41e-172 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
EMKMLPHE_01610 1.34e-245 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EMKMLPHE_01611 5.47e-75 cysG 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Putative NAD(P)-binding
EMKMLPHE_01612 9.25e-301 cobQ 6.3.5.10 - H ko:K02232 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
EMKMLPHE_01613 7.19e-155 cbiO - - P ko:K02006 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 part of an ABC transporter complex. Responsible for energy coupling to the transport system
EMKMLPHE_01614 1.88e-131 cbiQ - - P ko:K02008 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
EMKMLPHE_01615 8.36e-59 cbiN - - P ko:K02009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
EMKMLPHE_01616 3.86e-158 cbiM - - P ko:K02007 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
EMKMLPHE_01617 5.52e-117 cbiL 2.1.1.130, 2.1.1.151 - H ko:K03394 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Tetrapyrrole (Corrin/Porphyrin) Methylases
EMKMLPHE_01618 1.97e-138 cbiK 4.99.1.3 - H ko:K02190 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Cobalt chelatase (CbiK)
EMKMLPHE_01619 1.2e-223 cobA 2.1.1.107, 4.2.1.75 - H ko:K02303,ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapyrrole (Corrin/Porphyrin) Methylases
EMKMLPHE_01620 1.51e-125 cobK 1.3.1.106, 1.3.1.54 - H ko:K05895 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Precorrin-6x reductase CbiJ/CobK
EMKMLPHE_01621 2.29e-165 cbiH 2.1.1.131 - H ko:K05934 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Tetrapyrrole (Corrin/Porphyrin) Methylases
EMKMLPHE_01622 3.13e-181 cbiG 3.7.1.12 - H ko:K02189 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Cobalamin synthesis G C-terminus
EMKMLPHE_01623 5.75e-165 cbiF 2.1.1.133, 2.1.1.271 - H ko:K05936 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Tetrapyrrole (Corrin/Porphyrin) Methylases
EMKMLPHE_01624 2.45e-90 cbiT 2.1.1.196 - H ko:K02191 ko00860,map00860 ko00000,ko00001,ko01000 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
EMKMLPHE_01625 6.19e-102 cbiE 2.1.1.289 - H ko:K03399 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Tetrapyrrole (Corrin/Porphyrin) Methylases
EMKMLPHE_01626 1.39e-244 cbiD 2.1.1.195 - H ko:K02188 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
EMKMLPHE_01627 5.48e-139 cbiC 5.4.99.60, 5.4.99.61 - H ko:K06042 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Precorrin-8X methylmutase
EMKMLPHE_01628 4.35e-186 cobD 6.3.1.10 - H ko:K02227 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
EMKMLPHE_01629 2.22e-256 cbiA 6.3.5.11, 6.3.5.9 - F ko:K02224 ko00860,ko01100,ko01120,map00860,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source
EMKMLPHE_01630 2.83e-215 cobD 4.1.1.81 - E ko:K04720 ko00860,map00860 ko00000,ko00001,ko01000 Aminotransferase class I and II
EMKMLPHE_01631 1.72e-102 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Cobalamin adenosyltransferase
EMKMLPHE_01632 4.92e-147 nqo1 - - S ko:K19784 - ko00000 NADPH-dependent FMN reductase
EMKMLPHE_01633 6.45e-95 ykuP - - C ko:K03839 - ko00000 Flavodoxin
EMKMLPHE_01634 1.44e-90 eutP - - E ko:K04029 - ko00000 Ethanolamine utilisation - propanediol utilisation
EMKMLPHE_01635 3.45e-87 - - - P - - - Cadmium resistance transporter
EMKMLPHE_01636 3.03e-96 pgm1 - - G - - - phosphoglycerate mutase
EMKMLPHE_01637 7.99e-150 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Pfam:Y_phosphatase3C
EMKMLPHE_01638 9.15e-72 - - - E ko:K04031 - ko00000 BMC
EMKMLPHE_01639 2.5e-278 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EMKMLPHE_01640 4.33e-259 pduQ - - C ko:K13921 ko00640,map00640 ko00000,ko00001 Iron-containing alcohol dehydrogenase
EMKMLPHE_01641 0.0 pduP 1.2.1.87 - C ko:K13922 ko00640,map00640 ko00000,ko00001,ko01000 Aldehyde dehydrogenase family
EMKMLPHE_01642 1.62e-101 pduO - - S - - - Haem-degrading
EMKMLPHE_01643 2.85e-134 - - - S - - - Cobalamin adenosyltransferase
EMKMLPHE_01644 5.63e-55 pduN - - CQ ko:K04028 - ko00000 Ethanolamine utilisation protein EutN/carboxysome
EMKMLPHE_01645 1.25e-103 - - - S - - - Putative propanediol utilisation
EMKMLPHE_01646 1.98e-148 pduL 2.3.1.222 - Q ko:K13923 ko00640,map00640 ko00000,ko00001,ko01000 Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate
EMKMLPHE_01647 3.65e-53 pduA_2 - - CQ ko:K04027 - ko00000 BMC
EMKMLPHE_01648 9.33e-75 - - - CQ - - - BMC
EMKMLPHE_01649 1.31e-59 pduH - - S - - - Dehydratase medium subunit
EMKMLPHE_01650 0.0 pduG - - D - - - Diol dehydratase reactivase ATPase-like domain
EMKMLPHE_01651 8.85e-97 pduE 4.2.1.28 - Q ko:K13920 ko00640,map00640 ko00000,ko00001,ko01000 Dehydratase small subunit
EMKMLPHE_01652 5e-162 pduD 4.2.1.28 - Q ko:K13919 ko00640,map00640 ko00000,ko00001,ko01000 Dehydratase medium subunit
EMKMLPHE_01653 0.0 pduC 4.2.1.28 - Q ko:K01699 ko00640,map00640 ko00000,ko00001,ko01000 Dehydratase large subunit
EMKMLPHE_01654 3.41e-170 pduB - - E - - - BMC
EMKMLPHE_01655 2.33e-50 - - - CQ - - - BMC
EMKMLPHE_01656 1.69e-202 - - - K - - - helix_turn_helix, arabinose operon control protein
EMKMLPHE_01657 4.02e-177 eutJ - - E ko:K04024 - ko00000 Hsp70 protein
EMKMLPHE_01658 9.82e-173 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
EMKMLPHE_01659 8.24e-205 - - - - - - - -
EMKMLPHE_01660 8.07e-199 - - - G - - - Xylose isomerase domain protein TIM barrel
EMKMLPHE_01661 4.09e-235 XK27_12525 - - S - - - AI-2E family transporter
EMKMLPHE_01662 3.53e-169 XK27_07210 - - S - - - B3 4 domain
EMKMLPHE_01663 8.16e-103 yybA - - K - - - Transcriptional regulator
EMKMLPHE_01664 5.04e-116 - - - K - - - Domain of unknown function (DUF1836)
EMKMLPHE_01665 9.43e-116 - - - GM - - - epimerase
EMKMLPHE_01666 8.05e-198 - - - V - - - (ABC) transporter
EMKMLPHE_01667 1.79e-302 yhdP - - S - - - Transporter associated domain
EMKMLPHE_01668 3.16e-107 nrdI - - F ko:K03647 - ko00000 Belongs to the NrdI family
EMKMLPHE_01669 4.3e-96 - - - S ko:K04750 - ko00000 3-demethylubiquinone-9 3-methyltransferase
EMKMLPHE_01670 7.93e-242 yycB - - P ko:K03449 - ko00000,ko02000 Transporter, major facilitator family protein
EMKMLPHE_01671 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EMKMLPHE_01672 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EMKMLPHE_01673 4.67e-39 - - - - - - - -
EMKMLPHE_01674 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
EMKMLPHE_01677 3.37e-71 - - - L - - - Helix-turn-helix domain
EMKMLPHE_01678 1.75e-158 - - - O - - - Zinc-dependent metalloprotease
EMKMLPHE_01679 9.38e-115 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
EMKMLPHE_01680 1.84e-203 metQ1 - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
EMKMLPHE_01682 9.36e-36 - - - NU - - - Mycoplasma protein of unknown function, DUF285
EMKMLPHE_01683 1.54e-234 - - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
EMKMLPHE_01684 4.8e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EMKMLPHE_01685 1.07e-239 - - - - - - - -
EMKMLPHE_01686 2.74e-80 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EMKMLPHE_01687 1.71e-89 - 1.1.1.90 - C ko:K00055 ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Zn-dependent alcohol dehydrogenases, class III
EMKMLPHE_01688 4.96e-144 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
EMKMLPHE_01689 2.32e-126 - - - K - - - acetyltransferase
EMKMLPHE_01690 2.17e-243 - - - - - - - -
EMKMLPHE_01692 4.65e-167 - - - K ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C-terminal domain protein
EMKMLPHE_01693 1.64e-203 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
EMKMLPHE_01694 4.58e-194 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
EMKMLPHE_01695 2.7e-199 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
EMKMLPHE_01696 3.02e-175 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
EMKMLPHE_01697 6.09e-162 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
EMKMLPHE_01698 8.27e-191 - - - - - - - -
EMKMLPHE_01700 3.37e-308 - - - M - - - Glycosyl transferase
EMKMLPHE_01701 2.52e-286 - - - G - - - Glycosyl hydrolases family 8
EMKMLPHE_01702 1.33e-179 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
EMKMLPHE_01703 0.0 mycA 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
EMKMLPHE_01704 9.61e-305 ktrB - - P ko:K03498 - ko00000,ko02000 Potassium uptake protein
EMKMLPHE_01705 2.68e-150 ktrA - - P ko:K03499 - ko00000,ko02000 domain protein
EMKMLPHE_01706 1.12e-112 - - - Q - - - Methyltransferase
EMKMLPHE_01707 5.18e-291 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
EMKMLPHE_01708 2.69e-228 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
EMKMLPHE_01709 1.26e-214 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
EMKMLPHE_01710 1.76e-122 - - - S - - - NADPH-dependent FMN reductase
EMKMLPHE_01711 4.8e-229 - - - S - - - Conserved hypothetical protein 698
EMKMLPHE_01712 1.45e-171 - - - I - - - alpha/beta hydrolase fold
EMKMLPHE_01713 3.23e-213 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
EMKMLPHE_01714 1.56e-229 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Peroxidase
EMKMLPHE_01715 0.0 arcD - - S - - - C4-dicarboxylate anaerobic carrier
EMKMLPHE_01716 0.0 arcT - - E - - - Dipeptidase
EMKMLPHE_01717 6.33e-275 - - - EGP - - - Transporter, major facilitator family protein
EMKMLPHE_01718 0.0 gtfA 2.4.1.7 GH13 G ko:K00690 ko00500,map00500 ko00000,ko00001,ko01000 Sucrose glucosyltransferase
EMKMLPHE_01719 1.67e-179 - - - V - - - Beta-lactamase enzyme family
EMKMLPHE_01720 5.17e-290 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
EMKMLPHE_01721 5.36e-97 - - - - - - - -
EMKMLPHE_01722 1.5e-254 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
EMKMLPHE_01723 2.33e-29 - - - - - - - -
EMKMLPHE_01724 0.0 - - - S ko:K13730 ko05100,map05100 ko00000,ko00001 Uncharacterized protein conserved in bacteria (DUF2252)
EMKMLPHE_01725 1.22e-204 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
EMKMLPHE_01726 0.0 - - - L - - - PFAM plasmid pRiA4b ORF-3 family protein
EMKMLPHE_01727 3.86e-263 adh 1.1.1.1 - C ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Zinc-binding alcohol dehydrogenase family protein
EMKMLPHE_01728 6.76e-143 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EMKMLPHE_01729 1.44e-202 mleR - - K - - - LysR family
EMKMLPHE_01730 0.0 mleS 1.1.1.38, 4.1.1.101 - C ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme
EMKMLPHE_01731 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
EMKMLPHE_01732 0.0 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
EMKMLPHE_01733 0.0 citP - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
EMKMLPHE_01734 1.2e-203 - - - K - - - LysR family
EMKMLPHE_01735 0.0 - - - S - - - Putative threonine/serine exporter
EMKMLPHE_01736 6.38e-151 - 3.2.2.27 - L ko:K21929 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Uracil-DNA glycosylase
EMKMLPHE_01737 0.0 qacA - - EGP - - - Major Facilitator
EMKMLPHE_01738 3.06e-238 - - - I - - - Alpha beta
EMKMLPHE_01739 7.62e-132 - 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 DJ-1/PfpI family
EMKMLPHE_01740 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EMKMLPHE_01742 3.34e-212 yjbO 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
EMKMLPHE_01743 1.47e-157 - - - S - - - Domain of unknown function (DUF4811)
EMKMLPHE_01744 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
EMKMLPHE_01745 1.53e-97 - - - K - - - MerR HTH family regulatory protein
EMKMLPHE_01746 8.46e-77 - - - - - - - -
EMKMLPHE_01747 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EMKMLPHE_01749 0.000106 - 3.1.3.48 - D ko:K01104 - ko00000,ko01000 nuclear chromosome segregation
EMKMLPHE_01750 5.25e-110 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EMKMLPHE_01751 3.41e-267 yhdG - - E ko:K03294 - ko00000 Amino Acid
EMKMLPHE_01752 1.15e-226 - - - S - - - FRG
EMKMLPHE_01753 5.33e-103 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
EMKMLPHE_01754 2.87e-88 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
EMKMLPHE_01755 3.67e-153 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
EMKMLPHE_01756 1.09e-251 coiA - - S ko:K06198 - ko00000 Competence protein
EMKMLPHE_01757 0.0 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
EMKMLPHE_01758 3.29e-146 yjbH - - Q - - - Thioredoxin
EMKMLPHE_01759 7.45e-150 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
EMKMLPHE_01760 1.2e-195 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EMKMLPHE_01761 9.29e-220 yjbO 5.4.99.23 - G ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
EMKMLPHE_01762 1.02e-139 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
EMKMLPHE_01763 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
EMKMLPHE_01764 4.08e-147 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
EMKMLPHE_01765 3.01e-125 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EMKMLPHE_01766 1.25e-262 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
EMKMLPHE_01767 1.01e-186 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
EMKMLPHE_01768 7.65e-184 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
EMKMLPHE_01769 2.33e-264 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
EMKMLPHE_01770 4.88e-42 - - - - - - - -
EMKMLPHE_01771 5.07e-82 - - - - - - - -
EMKMLPHE_01772 8e-39 - - - - - - - -
EMKMLPHE_01774 1.05e-29 - - - D - - - nuclear chromosome segregation
EMKMLPHE_01779 1.62e-65 - - - - - - - -
EMKMLPHE_01780 1.2e-61 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
EMKMLPHE_01782 5.76e-236 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
EMKMLPHE_01783 2.7e-18 XK27_09155 - - K - - - Transcriptional
EMKMLPHE_01784 2.79e-130 cadD - - P - - - Cadmium resistance transporter
EMKMLPHE_01785 2.07e-73 cadX - - K ko:K21903 - ko00000,ko03000 Bacterial regulatory protein, arsR family
EMKMLPHE_01786 1.31e-93 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EMKMLPHE_01787 2.52e-232 arsB - - P ko:K03325 - ko00000,ko02000 Sodium Bile acid symporter family
EMKMLPHE_01788 1.73e-56 arsR - - K ko:K03892 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
EMKMLPHE_01789 1.47e-81 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EMKMLPHE_01790 2.92e-57 arsB - - P ko:K03325 - ko00000,ko02000 Sodium Bile acid symporter family
EMKMLPHE_01791 4.15e-23 - - - K - - - Helix-turn-helix domain
EMKMLPHE_01792 2.27e-24 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
EMKMLPHE_01793 0.0 - - - S - - - ABC transporter, ATP-binding protein
EMKMLPHE_01794 2.81e-184 - - - S - - - Putative ABC-transporter type IV
EMKMLPHE_01795 2.85e-135 - - - NU - - - mannosyl-glycoprotein
EMKMLPHE_01796 5.41e-316 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
EMKMLPHE_01797 8.26e-290 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
EMKMLPHE_01798 4.53e-263 yngD - - S ko:K07097 - ko00000 DHHA1 domain
EMKMLPHE_01799 1.43e-41 - - - S - - - PD-(D/E)XK nuclease family transposase
EMKMLPHE_01809 5.19e-127 - - - K - - - Acetyltransferase (GNAT) domain
EMKMLPHE_01810 1.66e-305 lmrB - - U ko:K18926 - ko00000,ko00002,ko02000 Belongs to the major facilitator superfamily
EMKMLPHE_01811 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
EMKMLPHE_01812 4.6e-143 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EMKMLPHE_01813 1.76e-201 - - - O - - - Uncharacterized protein family (UPF0051)
EMKMLPHE_01814 5.35e-86 - - - M - - - LysM domain protein
EMKMLPHE_01815 0.0 - - - EP - - - Psort location Cytoplasmic, score
EMKMLPHE_01816 8.05e-132 - - - M - - - LysM domain protein
EMKMLPHE_01817 2.23e-187 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
EMKMLPHE_01818 6.91e-299 - 1.3.1.1 - E ko:K17722 ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
EMKMLPHE_01819 1.32e-308 - 1.3.1.1 - C ko:K17723 ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100 ko00000,ko00001,ko00002,ko01000 4Fe-4S dicluster domain
EMKMLPHE_01820 1.23e-194 yeaE - - S - - - Aldo keto
EMKMLPHE_01821 3.81e-100 hsp - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
EMKMLPHE_01822 0.0 umuC - - L ko:K03502 - ko00000,ko03400 impB/mucB/samB family C-terminal domain
EMKMLPHE_01823 4.4e-101 - - - S - - - Psort location Cytoplasmic, score
EMKMLPHE_01824 1e-101 - - - S - - - Short repeat of unknown function (DUF308)
EMKMLPHE_01825 2.1e-59 - - - L - - - Reverse transcriptase (RNA-dependent DNA polymerase)
EMKMLPHE_01826 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
EMKMLPHE_01827 1.5e-226 pepR 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
EMKMLPHE_01828 0.0 atp2C1 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
EMKMLPHE_01829 1.19e-111 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
EMKMLPHE_01830 1.56e-222 yagE - - E - - - amino acid
EMKMLPHE_01831 2.14e-148 - - - S - - - HAD hydrolase, family IA, variant
EMKMLPHE_01832 7.54e-122 - - - S - - - PD-(D/E)XK nuclease family transposase
EMKMLPHE_01833 1.69e-44 - - - S - - - PD-(D/E)XK nuclease family transposase
EMKMLPHE_01834 4.85e-233 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
EMKMLPHE_01835 5.46e-233 iunH1 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 nucleoside hydrolase
EMKMLPHE_01850 6.73e-51 - - - S - - - Cytochrome B5
EMKMLPHE_01851 2.69e-79 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
EMKMLPHE_01852 0.0 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
EMKMLPHE_01853 7.01e-244 - - - E - - - Zinc-binding dehydrogenase
EMKMLPHE_01854 1.46e-110 - - - K - - - transcriptional regulator (TetR family)
EMKMLPHE_01855 7.46e-222 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
EMKMLPHE_01856 2.37e-152 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EMKMLPHE_01857 0.0 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EMKMLPHE_01858 1.61e-48 - - - - - - - -
EMKMLPHE_01859 3.35e-65 czrA - - K ko:K22043 - ko00000,ko03000 Transcriptional regulator, ArsR family
EMKMLPHE_01860 0.0 - 3.2.1.17 CBM50 NU ko:K01185,ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
EMKMLPHE_01861 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
EMKMLPHE_01862 2.07e-303 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
EMKMLPHE_01863 1.07e-237 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
EMKMLPHE_01864 6.71e-92 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
EMKMLPHE_01865 1e-31 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
EMKMLPHE_01866 0.0 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
EMKMLPHE_01867 2.57e-169 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
EMKMLPHE_01868 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
EMKMLPHE_01869 3.1e-213 - - - G - - - Phosphotransferase enzyme family
EMKMLPHE_01870 1.88e-101 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
EMKMLPHE_01871 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EMKMLPHE_01872 1.94e-68 - - - - - - - -
EMKMLPHE_01873 1.31e-162 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
EMKMLPHE_01874 1.89e-228 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
EMKMLPHE_01875 3.36e-77 - - - - - - - -
EMKMLPHE_01876 6.51e-220 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
EMKMLPHE_01878 1.18e-253 - - - C - - - Belongs to the LDH2 MDH2 oxidoreductase family
EMKMLPHE_01879 0.0 pepD3 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
EMKMLPHE_01880 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
EMKMLPHE_01881 2.2e-273 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
EMKMLPHE_01882 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
EMKMLPHE_01883 3.69e-114 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EMKMLPHE_01884 7.6e-246 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
EMKMLPHE_01885 1.04e-83 - - - - - - - -
EMKMLPHE_01886 3.13e-225 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
EMKMLPHE_01887 2.63e-210 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EMKMLPHE_01888 1.38e-77 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EMKMLPHE_01889 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EMKMLPHE_01890 7.97e-65 ylxQ - - J - - - ribosomal protein
EMKMLPHE_01891 5.93e-60 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
EMKMLPHE_01892 3.39e-274 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
EMKMLPHE_01893 6.36e-108 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
EMKMLPHE_01894 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EMKMLPHE_01895 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
EMKMLPHE_01896 9.45e-298 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
EMKMLPHE_01897 5.83e-178 cdsA 2.7.7.41 - I ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
EMKMLPHE_01898 1.29e-182 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EMKMLPHE_01899 3.48e-122 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
EMKMLPHE_01900 1.72e-166 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
EMKMLPHE_01901 1.82e-196 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EMKMLPHE_01902 2.91e-183 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
EMKMLPHE_01903 1.62e-230 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EMKMLPHE_01904 9.65e-65 yazA - - L ko:K07461 - ko00000 GIY-YIG catalytic domain protein
EMKMLPHE_01905 5.67e-180 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
EMKMLPHE_01906 7.51e-152 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
EMKMLPHE_01907 1.6e-40 XK26_06720 - - S ko:K09976 - ko00000 Uncharacterised protein family (UPF0154)
EMKMLPHE_01908 2.7e-47 ynzC - - S - - - UPF0291 protein
EMKMLPHE_01909 2.52e-148 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EMKMLPHE_01910 5.32e-266 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
EMKMLPHE_01911 7.21e-164 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EMKMLPHE_01913 1.26e-121 - - - - - - - -
EMKMLPHE_01914 5.09e-119 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EMKMLPHE_01915 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
EMKMLPHE_01916 9.7e-198 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
EMKMLPHE_01917 2.79e-225 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
EMKMLPHE_01918 1.69e-314 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EMKMLPHE_01919 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
EMKMLPHE_01920 4.93e-20 - - - - - - - -
EMKMLPHE_01921 1.11e-78 - - - S - - - mazG nucleotide pyrophosphohydrolase
EMKMLPHE_01922 2.01e-139 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
EMKMLPHE_01923 2.06e-297 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EMKMLPHE_01924 3.2e-302 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
EMKMLPHE_01925 4.94e-288 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EMKMLPHE_01926 1.25e-208 - - - S - - - Tetratricopeptide repeat
EMKMLPHE_01927 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EMKMLPHE_01928 1.74e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EMKMLPHE_01929 1.44e-47 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
EMKMLPHE_01930 2.27e-200 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
EMKMLPHE_01931 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
EMKMLPHE_01932 2.47e-116 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
EMKMLPHE_01933 4.83e-138 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
EMKMLPHE_01934 8.27e-250 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
EMKMLPHE_01935 3.05e-116 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EMKMLPHE_01936 4.59e-127 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
EMKMLPHE_01937 6.37e-60 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
EMKMLPHE_01938 1.07e-283 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
EMKMLPHE_01939 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
EMKMLPHE_01940 4.59e-173 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the inositol monophosphatase superfamily
EMKMLPHE_01941 1.32e-59 yktA - - S - - - Belongs to the UPF0223 family
EMKMLPHE_01942 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
EMKMLPHE_01943 1.23e-310 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
EMKMLPHE_01944 1.34e-231 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Transketolase, C-terminal domain protein
EMKMLPHE_01945 6.71e-265 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
EMKMLPHE_01946 2.78e-132 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
EMKMLPHE_01947 3.66e-103 - - - - - - - -
EMKMLPHE_01948 9.99e-44 ykzG - - S - - - Belongs to the UPF0356 family
EMKMLPHE_01949 4.14e-230 - - - I - - - Diacylglycerol kinase catalytic
EMKMLPHE_01950 4.37e-39 - - - - - - - -
EMKMLPHE_01951 2.51e-217 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
EMKMLPHE_01953 2.15e-75 - - - - - - - -
EMKMLPHE_01954 3.74e-265 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
EMKMLPHE_01955 6.34e-279 yojA - - EG ko:K03299 - ko00000,ko02000 GntP family permease
EMKMLPHE_01956 5.77e-104 - - - KT ko:K02647 - ko00000,ko03000 Putative sugar diacid recognition
EMKMLPHE_01957 4.47e-255 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EMKMLPHE_01958 5.91e-279 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
EMKMLPHE_01959 1.56e-181 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
EMKMLPHE_01960 1.09e-221 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EMKMLPHE_01961 2.32e-283 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
EMKMLPHE_01962 4.39e-110 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
EMKMLPHE_01963 1.09e-309 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
EMKMLPHE_01964 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
EMKMLPHE_01965 2.6e-233 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EMKMLPHE_01966 3.49e-222 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EMKMLPHE_01967 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
EMKMLPHE_01968 5.21e-155 - - - S - - - repeat protein
EMKMLPHE_01969 5.71e-159 pgm6 - - G - - - phosphoglycerate mutase
EMKMLPHE_01970 8.77e-286 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
EMKMLPHE_01971 5.58e-76 XK27_04120 - - S - - - Putative amino acid metabolism
EMKMLPHE_01972 4.48e-278 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
EMKMLPHE_01973 6.59e-160 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EMKMLPHE_01974 1.19e-25 - - - - - - - -
EMKMLPHE_01975 1.44e-128 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
EMKMLPHE_01976 5.69e-44 cspB - - K ko:K03704 - ko00000,ko03000 Cold shock protein
EMKMLPHE_01977 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EMKMLPHE_01978 3.1e-101 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
EMKMLPHE_01979 1.76e-188 ylmH - - S - - - S4 domain protein
EMKMLPHE_01980 3.2e-54 ylmG - - S ko:K02221 - ko00000,ko02044 YGGT family
EMKMLPHE_01981 4.51e-92 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
EMKMLPHE_01982 8.44e-284 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EMKMLPHE_01983 0.0 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
EMKMLPHE_01984 5.77e-184 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
EMKMLPHE_01985 1.98e-258 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EMKMLPHE_01986 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EMKMLPHE_01987 7.73e-230 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EMKMLPHE_01988 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
EMKMLPHE_01989 2.85e-72 ftsL - - D - - - Cell division protein FtsL
EMKMLPHE_01990 1.04e-220 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
EMKMLPHE_01991 1.5e-101 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
EMKMLPHE_01992 5.06e-77 - - - - - - - -
EMKMLPHE_01993 4.47e-16 - - - S - - - Protein of unknown function (DUF4044)
EMKMLPHE_01994 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
EMKMLPHE_01995 1.53e-123 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
EMKMLPHE_01996 2.24e-203 rrmA 2.1.1.187 - H ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 Methyltransferase
EMKMLPHE_01997 1.88e-251 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
EMKMLPHE_01999 2.8e-81 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
EMKMLPHE_02000 3.44e-12 - - - L ko:K07484 - ko00000 Transposase IS66 family
EMKMLPHE_02001 2.03e-141 - - - L - - - Bacterial dnaA protein
EMKMLPHE_02002 6.08e-171 - - - L - - - Integrase core domain
EMKMLPHE_02003 1.19e-188 - - - L ko:K07484 - ko00000 Transposase IS66 family
EMKMLPHE_02004 1.58e-22 - - - L ko:K07484 - ko00000 Transposase IS66 family
EMKMLPHE_02005 2.13e-85 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
EMKMLPHE_02006 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
EMKMLPHE_02008 1.98e-278 - - - S ko:K07133 - ko00000 cog cog1373
EMKMLPHE_02009 8.32e-226 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
EMKMLPHE_02010 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
EMKMLPHE_02011 2.62e-204 - - - EG - - - EamA-like transporter family
EMKMLPHE_02012 7.33e-48 - - - Q - - - pyridine nucleotide-disulphide oxidoreductase
EMKMLPHE_02013 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
EMKMLPHE_02014 4.66e-148 - - - S ko:K03975 - ko00000 SNARE associated Golgi protein
EMKMLPHE_02015 3.87e-161 pgm3 - - G - - - phosphoglycerate mutase
EMKMLPHE_02016 4.64e-294 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EMKMLPHE_02017 5.25e-45 - - - S - - - Transglycosylase associated protein
EMKMLPHE_02018 2.63e-09 - - - S - - - CsbD-like
EMKMLPHE_02019 3.05e-230 - 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EMKMLPHE_02020 0.0 yhgE - - V ko:K01421 - ko00000 domain protein
EMKMLPHE_02021 1.76e-122 - - - K - - - Transcriptional regulator (TetR family)
EMKMLPHE_02022 6.09e-53 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 positive regulation of macromolecule biosynthetic process
EMKMLPHE_02023 9e-191 - - - - - - - -
EMKMLPHE_02024 5.45e-35 - 3.2.1.14 GH18 - ko:K01183 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 -
EMKMLPHE_02025 4.26e-107 zur - - P ko:K02076,ko:K03711 - ko00000,ko03000 Belongs to the Fur family
EMKMLPHE_02026 2.86e-127 gmk2 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Guanylate kinase
EMKMLPHE_02027 1.78e-97 - - - F - - - Nudix hydrolase
EMKMLPHE_02028 0.0 yhdG - - E ko:K03294 - ko00000 Amino Acid
EMKMLPHE_02029 3.27e-294 - - - EGP ko:K08368 - ko00000,ko02000 Sugar (and other) transporter
EMKMLPHE_02030 8.76e-64 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
EMKMLPHE_02031 6.17e-38 spxB 1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8 - EH ko:K00156,ko:K00158,ko:K01577,ko:K01652 ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
EMKMLPHE_02032 9.17e-250 spxB 1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8 - EH ko:K00156,ko:K00158,ko:K01577,ko:K01652 ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
EMKMLPHE_02033 6.75e-28 spxB 1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8 - EH ko:K00156,ko:K00158,ko:K01577,ko:K01652 ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
EMKMLPHE_02034 1.14e-178 - - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
EMKMLPHE_02035 2.41e-179 - - - S - - - Membrane
EMKMLPHE_02036 1.36e-96 - 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase
EMKMLPHE_02037 1.14e-27 - - - - - - - -
EMKMLPHE_02038 8.27e-111 XK27_05190 - - S - - - Protein of unknown function (DUF1694)
EMKMLPHE_02039 3.64e-307 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
EMKMLPHE_02040 1.04e-60 - - - - - - - -
EMKMLPHE_02041 1.95e-109 uspA - - T - - - universal stress protein
EMKMLPHE_02042 3.29e-259 araR - - K ko:K02103 - ko00000,ko03000 Transcriptional regulator
EMKMLPHE_02043 5.7e-199 yvgN - - S - - - Aldo keto reductase
EMKMLPHE_02044 2.65e-38 maa 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
EMKMLPHE_02045 1.9e-66 maa 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
EMKMLPHE_02046 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
EMKMLPHE_02047 1.34e-178 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
EMKMLPHE_02048 0.0 araB 2.7.1.16 - G ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 carbohydrate kinase FGGY
EMKMLPHE_02049 0.0 araP - - U - - - Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
EMKMLPHE_02050 8.63e-190 - - - K - - - Helix-turn-helix XRE-family like proteins
EMKMLPHE_02051 7.38e-274 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
EMKMLPHE_02052 8.55e-64 gcsH2 - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 glycine cleavage
EMKMLPHE_02053 9.49e-282 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
EMKMLPHE_02054 4.61e-44 - - - S - - - Protein of unknown function (DUF2969)
EMKMLPHE_02055 2.57e-227 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
EMKMLPHE_02056 4.97e-307 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EMKMLPHE_02057 1.76e-45 ywzB - - S - - - Protein of unknown function (DUF1146)
EMKMLPHE_02058 7.36e-89 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
EMKMLPHE_02059 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EMKMLPHE_02060 7.51e-212 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EMKMLPHE_02061 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EMKMLPHE_02062 6.84e-121 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EMKMLPHE_02063 1.07e-95 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EMKMLPHE_02064 1.26e-29 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EMKMLPHE_02065 4.63e-162 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
EMKMLPHE_02066 2.8e-294 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
EMKMLPHE_02067 1.41e-167 yibF - - S - - - overlaps another CDS with the same product name
EMKMLPHE_02068 1.65e-246 yibE - - S - - - overlaps another CDS with the same product name
EMKMLPHE_02069 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EMKMLPHE_02070 6.68e-150 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EMKMLPHE_02071 1.22e-291 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EMKMLPHE_02072 1.09e-250 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
EMKMLPHE_02073 9.58e-211 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
EMKMLPHE_02074 1.73e-248 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EMKMLPHE_02075 6.8e-140 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
EMKMLPHE_02076 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Mur ligase, middle domain
EMKMLPHE_02077 2.82e-172 - - - S ko:K07009 - ko00000 CobB/CobQ-like glutamine amidotransferase domain
EMKMLPHE_02079 3.26e-296 potE - - U ko:K03756,ko:K03758 - ko00000,ko02000 Amino acid permease
EMKMLPHE_02080 0.0 arcD - - E ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
EMKMLPHE_02081 1.24e-103 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
EMKMLPHE_02082 1.54e-289 arcA 3.5.3.6 - E ko:K01478 ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130 ko00000,ko00001,ko01000 Arginine
EMKMLPHE_02083 3.4e-232 ampC - - V - - - Beta-lactamase
EMKMLPHE_02084 9.2e-67 - - - - - - - -
EMKMLPHE_02085 1.15e-263 - - - M - - - domain protein
EMKMLPHE_02086 0.0 - - - M - - - domain protein
EMKMLPHE_02087 2.44e-137 - - - - - - - -
EMKMLPHE_02088 2.49e-169 int2 - - L - - - Belongs to the 'phage' integrase family
EMKMLPHE_02089 1.17e-20 - - - S - - - sequence-specific DNA binding
EMKMLPHE_02090 2.16e-20 - - - - - - - -
EMKMLPHE_02091 4.91e-55 - - - S - - - Phage regulatory protein Rha (Phage_pRha)
EMKMLPHE_02092 5.44e-07 - - - S - - - Helix-turn-helix domain
EMKMLPHE_02098 6.03e-13 - - - L - - - DnaD domain protein
EMKMLPHE_02100 1.37e-86 - - - - - - - -
EMKMLPHE_02103 1.42e-71 - - - - - - - -
EMKMLPHE_02105 5.75e-124 nhaP3 - - P ko:K03316 - ko00000 Sodium proton antiporter
EMKMLPHE_02106 2.91e-98 nhaP3 - - P ko:K03316 - ko00000 Sodium proton antiporter
EMKMLPHE_02107 3.72e-48 nhaP3 - - P ko:K03316 - ko00000 Sodium proton antiporter
EMKMLPHE_02108 1.5e-74 - - - - - - - -
EMKMLPHE_02110 7.13e-110 - - - - - - - -
EMKMLPHE_02111 0.0 copA 3.6.3.3, 3.6.3.5, 3.6.3.54 - P ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
EMKMLPHE_02112 2.18e-80 - - - S - - - Cupredoxin-like domain
EMKMLPHE_02113 7.03e-134 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
EMKMLPHE_02114 1.62e-203 - - - EG - - - EamA-like transporter family
EMKMLPHE_02115 3.94e-221 arcC 2.7.2.2 - E ko:K00926 ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200 ko00000,ko00001,ko01000 Belongs to the carbamate kinase family
EMKMLPHE_02116 7.57e-243 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EMKMLPHE_02117 1.06e-198 - - - KT ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 YcbB domain
EMKMLPHE_02118 3.42e-41 xylB 2.7.1.17, 2.7.1.53 - G ko:K00854,ko:K00880 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the FGGY kinase family
EMKMLPHE_02120 1.1e-35 - - - - - - - -
EMKMLPHE_02121 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
EMKMLPHE_02122 1.07e-138 maa3 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
EMKMLPHE_02123 2.14e-197 - - - U ko:K05340 - ko00000,ko02000 sugar transport
EMKMLPHE_02124 0.0 yclK - - T - - - Histidine kinase
EMKMLPHE_02125 4e-174 yclJ - - K ko:K02483 - ko00000,ko02022 response regulator
EMKMLPHE_02127 6.22e-107 lytE - - M - - - Lysin motif
EMKMLPHE_02128 5.46e-191 - - - S - - - Cof-like hydrolase
EMKMLPHE_02129 6.2e-103 - - - K - - - Transcriptional regulator
EMKMLPHE_02130 0.0 oatA - - I - - - Acyltransferase
EMKMLPHE_02131 3e-69 - - - - - - - -
EMKMLPHE_02132 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
EMKMLPHE_02133 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EMKMLPHE_02134 4.67e-164 ybbR - - S - - - YbbR-like protein
EMKMLPHE_02135 6.61e-195 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EMKMLPHE_02136 0.0 fucP - - G ko:K02429 - ko00000,ko02000 Major Facilitator Superfamily
EMKMLPHE_02137 1.01e-87 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
EMKMLPHE_02138 1.25e-211 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EMKMLPHE_02139 2.76e-215 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
EMKMLPHE_02140 7.18e-131 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
EMKMLPHE_02141 2.92e-98 XK27_04775 - - S ko:K09155 - ko00000 PAS domain
EMKMLPHE_02142 2.63e-115 - - - K - - - Acetyltransferase (GNAT) domain
EMKMLPHE_02143 3.44e-105 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
EMKMLPHE_02144 1.38e-228 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
EMKMLPHE_02145 1.07e-173 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EMKMLPHE_02146 9.61e-137 - - - - - - - -
EMKMLPHE_02147 7.73e-109 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
EMKMLPHE_02148 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
EMKMLPHE_02149 3e-171 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Serine aminopeptidase, S33
EMKMLPHE_02150 1.43e-47 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
EMKMLPHE_02151 0.0 eriC - - P ko:K03281 - ko00000 chloride
EMKMLPHE_02152 1.81e-316 yifK - - E ko:K03293 - ko00000 Amino acid permease
EMKMLPHE_02153 0.0 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
EMKMLPHE_02154 1.45e-181 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
EMKMLPHE_02155 1.04e-287 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
EMKMLPHE_02156 1.31e-243 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
EMKMLPHE_02158 4.72e-134 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
EMKMLPHE_02160 6.21e-62 ywnA - - K - - - Transcriptional regulator
EMKMLPHE_02161 1.96e-53 - - - S - - - ECF transporter, substrate-specific component
EMKMLPHE_02162 3.51e-253 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
EMKMLPHE_02163 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
EMKMLPHE_02164 2.41e-156 - - - T - - - Putative diguanylate phosphodiesterase
EMKMLPHE_02165 7.13e-247 - 2.7.7.65 - T ko:K02488 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko00002,ko01000,ko02022 GGDEF domain
EMKMLPHE_02166 3.3e-100 - - - - - - - -
EMKMLPHE_02176 1.22e-228 ycsG - - P - - - Natural resistance-associated macrophage protein
EMKMLPHE_02177 4.64e-130 - - - S ko:K07160 - ko00000 LamB/YcsF family
EMKMLPHE_02178 3.88e-260 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
EMKMLPHE_02179 5.44e-51 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
EMKMLPHE_02180 1.09e-134 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
EMKMLPHE_02181 8.61e-108 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
EMKMLPHE_02182 7.19e-53 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
EMKMLPHE_02184 1.9e-135 hdhL 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
EMKMLPHE_02185 1.13e-68 hdhL 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
EMKMLPHE_02186 7.48e-194 mhpD - - Q ko:K02509 ko00350,ko01120,map00350,map01120 ko00000,ko00001,ko01000 hydratase
EMKMLPHE_02187 2.31e-81 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
EMKMLPHE_02188 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EMKMLPHE_02189 0.0 sufI - - Q - - - Multicopper oxidase
EMKMLPHE_02190 8.24e-170 - - - L - - - PFAM Integrase catalytic region
EMKMLPHE_02193 2.59e-137 - - - - - - - -
EMKMLPHE_02194 1.34e-98 - - - - - - - -
EMKMLPHE_02195 1.75e-60 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
EMKMLPHE_02196 4.51e-54 - - - S - - - Phage head-tail joining protein
EMKMLPHE_02197 1.64e-89 - - - S - - - Phage gp6-like head-tail connector protein
EMKMLPHE_02198 4.12e-93 - - - S - - - Phage capsid family
EMKMLPHE_02199 5.97e-156 - - - S - - - Phage capsid family
EMKMLPHE_02200 3.54e-148 - - - S ko:K06904 - ko00000 Caudovirus prohead serine protease
EMKMLPHE_02201 2.96e-303 - - - S - - - Phage portal protein
EMKMLPHE_02204 0.0 terL - - S - - - overlaps another CDS with the same product name
EMKMLPHE_02205 8.04e-101 - - - L - - - Phage terminase, small subunit
EMKMLPHE_02206 1.44e-194 - - - L - - - HNH nucleases
EMKMLPHE_02210 3.15e-108 - - - S - - - Phage transcriptional regulator, ArpU family
EMKMLPHE_02212 8.94e-92 XK27_00160 - - S - - - Domain of unknown function (DUF5052)
EMKMLPHE_02216 7.57e-163 - - - - - - - -
EMKMLPHE_02217 8.03e-92 - - - - - - - -
EMKMLPHE_02219 2.18e-54 - - - S - - - HNH endonuclease
EMKMLPHE_02222 3.03e-176 - - - L - - - Belongs to the 'phage' integrase family
EMKMLPHE_02223 2.33e-112 - - - V - - - site-specific DNA-methyltransferase (adenine-specific) activity
EMKMLPHE_02224 6.94e-176 - - - L - - - DnaD domain protein
EMKMLPHE_02227 1.62e-26 - - - - - - - -
EMKMLPHE_02228 3.87e-23 - - - K - - - Cro/C1-type HTH DNA-binding domain
EMKMLPHE_02229 3.69e-32 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
EMKMLPHE_02236 9.06e-15 - - - K - - - Helix-turn-helix XRE-family like proteins
EMKMLPHE_02237 9.75e-101 - - - K - - - Peptidase S24-like
EMKMLPHE_02241 3.95e-29 - - - - - - - -
EMKMLPHE_02243 4.15e-49 - - - - - - - -
EMKMLPHE_02246 3.12e-90 - - - S - - - Domain of unknown function (DUF4393)
EMKMLPHE_02248 1.64e-178 int2 - - L - - - Belongs to the 'phage' integrase family
EMKMLPHE_02250 1.37e-64 - - - S - - - Lipopolysaccharide assembly protein A domain
EMKMLPHE_02251 5.84e-194 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
EMKMLPHE_02252 1.38e-117 ntd 2.4.2.6 - F ko:K08728 ko00240,map00240 ko00000,ko00001,ko01000 Nucleoside
EMKMLPHE_02253 1.15e-25 - - - - - - - -
EMKMLPHE_02254 6.99e-208 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
EMKMLPHE_02255 5.93e-149 - - - S - - - Protein of unknown function (DUF421)
EMKMLPHE_02256 3.91e-95 - - - S - - - Protein of unknown function (DUF3290)
EMKMLPHE_02257 8.32e-56 - - - S ko:K09790 - ko00000 Protein of unknown function (DUF454)
EMKMLPHE_02258 0.0 - - - I - - - Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EMKMLPHE_02259 1.99e-201 endA - - V ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
EMKMLPHE_02260 0.0 yifK - - E ko:K03293 - ko00000 Amino acid permease
EMKMLPHE_02262 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EMKMLPHE_02263 6.05e-290 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
EMKMLPHE_02264 9.71e-157 - - - S - - - SNARE associated Golgi protein
EMKMLPHE_02265 3.33e-53 uvrA2 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 excinuclease ABC, A subunit
EMKMLPHE_02266 2.44e-266 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
EMKMLPHE_02267 1.76e-313 - 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 pyridine nucleotide-disulfide oxidoreductase
EMKMLPHE_02268 3.38e-109 yvbK - - K - - - GNAT family
EMKMLPHE_02269 4.18e-119 - - - - - - - -
EMKMLPHE_02270 5.93e-156 pnb - - C - - - nitroreductase
EMKMLPHE_02271 2.07e-97 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Methyltransferase
EMKMLPHE_02272 2.36e-216 - 3.2.1.96, 3.5.1.28 GH73 M ko:K01227,ko:K01447,ko:K13714,ko:K13731 ko00511,ko05100,map00511,map05100 ko00000,ko00001,ko01000 N-acetylmuramoyl-L-alanine amidase
EMKMLPHE_02273 2.62e-89 - - - S - - - Protein of unknown function (DUF3021)
EMKMLPHE_02274 1.43e-100 - - - K - - - LytTr DNA-binding domain
EMKMLPHE_02275 1.46e-119 - - - K - - - Acetyltransferase (GNAT) family
EMKMLPHE_02276 5.37e-37 - - - - - - - -
EMKMLPHE_02277 9.22e-129 - - - K - - - DNA-templated transcription, initiation
EMKMLPHE_02278 1.33e-47 - - - - - - - -
EMKMLPHE_02279 3.21e-115 - - - - - - - -
EMKMLPHE_02280 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EMKMLPHE_02281 1.89e-35 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
EMKMLPHE_02282 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
EMKMLPHE_02283 0.0 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
EMKMLPHE_02284 1.28e-70 - - - - - - - -
EMKMLPHE_02285 0.0 - - - S - - - Putative peptidoglycan binding domain
EMKMLPHE_02288 3.99e-68 - - - L - - - An automated process has identified a potential problem with this gene model
EMKMLPHE_02289 1.79e-111 - - - K - - - FR47-like protein
EMKMLPHE_02290 2.79e-97 - - - O - - - OsmC-like protein
EMKMLPHE_02291 3.47e-221 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EMKMLPHE_02292 1.13e-272 - - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
EMKMLPHE_02293 2.49e-43 - - - - - - - -
EMKMLPHE_02294 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 associated with various cellular activities
EMKMLPHE_02296 1.12e-135 - - - K - - - PFAM GCN5-related N-acetyltransferase
EMKMLPHE_02297 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EMKMLPHE_02298 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
EMKMLPHE_02299 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
EMKMLPHE_02300 5.18e-222 malR1 - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
EMKMLPHE_02301 2.2e-273 atoB 1.1.1.88, 2.3.1.9 - I ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
EMKMLPHE_02302 0.0 malT - - G ko:K16211 - ko00000,ko02000 Major Facilitator
EMKMLPHE_02303 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
EMKMLPHE_02304 2.05e-153 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
EMKMLPHE_02305 8.84e-94 - - - - - - - -
EMKMLPHE_02306 1.24e-112 - - - T - - - Region found in RelA / SpoT proteins
EMKMLPHE_02307 3.15e-153 dltr - - K - - - response regulator
EMKMLPHE_02308 3.23e-289 sptS - - T - - - Histidine kinase
EMKMLPHE_02309 1.38e-272 - - - P - - - Voltage gated chloride channel
EMKMLPHE_02310 0.0 gshAB 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
EMKMLPHE_02311 2.5e-174 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
EMKMLPHE_02312 1.48e-214 - - - C - - - Aldo keto reductase
EMKMLPHE_02313 0.0 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Membrane domain of glycerophosphoryl diester phosphodiesterase
EMKMLPHE_02314 6.51e-114 - - - S - - - ECF-type riboflavin transporter, S component
EMKMLPHE_02315 0.0 nox 1.6.3.4 - C ko:K17869 - ko00000,ko01000 NADH oxidase
EMKMLPHE_02316 2.95e-239 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
EMKMLPHE_02317 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EMKMLPHE_02318 2.55e-121 - - - - - - - -
EMKMLPHE_02319 4.65e-123 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EMKMLPHE_02321 8.95e-18 - - - E - - - amino acid
EMKMLPHE_02322 2.53e-17 - - - K - - - Transcriptional regulator, TetR family
EMKMLPHE_02323 1.13e-96 - - - K - - - Transcriptional regulator, TetR family
EMKMLPHE_02324 8.53e-95 - - - - - - - -
EMKMLPHE_02325 5.5e-99 tagE 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
EMKMLPHE_02327 3.83e-70 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
EMKMLPHE_02328 4.75e-240 - - - L ko:K07484 - ko00000 Transposase IS66 family
EMKMLPHE_02329 3.39e-92 - - - L - - - An automated process has identified a potential problem with this gene model

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)