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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
COOLPGFE_00001	4.64e-139	pncA	-	-	Q	-	-	-	Isochorismatase family
COOLPGFE_00002	2.87e-151	-	-	-	-	-	-	-	-
COOLPGFE_00003	1.9e-56	-	-	-	L	-	-	-	Membrane
COOLPGFE_00004	2.32e-187	-	-	-	F	-	-	-	NUDIX domain
COOLPGFE_00005	1.14e-38	-	-	-	S	-	-	-	Enterocin A Immunity
COOLPGFE_00007	3.74e-149	-	-	-	E	-	-	-	peptidase
COOLPGFE_00008	5.53e-174	-	-	-	V	-	-	-	ABC-2 type transporter
COOLPGFE_00009	6.61e-167	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
COOLPGFE_00010	2.71e-07	-	-	-	KLT	-	-	-	Protein tyrosine kinase
COOLPGFE_00011	4.83e-153	-	-	-	-	-	-	-	-
COOLPGFE_00013	9.25e-247	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
COOLPGFE_00014	2.79e-117	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	MafB19-like deaminase
COOLPGFE_00015	7.13e-134	-	-	-	S	ko:K06872	-	ko00000	TPM domain
COOLPGFE_00016	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
COOLPGFE_00017	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
COOLPGFE_00018	5.49e-191	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
COOLPGFE_00019	3.34e-126	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
COOLPGFE_00020	1.57e-204	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
COOLPGFE_00021	4.13e-51	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
COOLPGFE_00022	4.31e-192	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
COOLPGFE_00023	0.0	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
COOLPGFE_00024	7.9e-60	-	-	-	-	-	-	-	-
COOLPGFE_00025	1.27e-225	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
COOLPGFE_00026	0.0	-	-	-	S	ko:K06885	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
COOLPGFE_00027	1.73e-84	-	-	-	S	-	-	-	Domain of unknown function (DUF1934)
COOLPGFE_00028	3.45e-91	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
COOLPGFE_00029	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
COOLPGFE_00030	1.26e-306	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
COOLPGFE_00031	3.27e-55	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
COOLPGFE_00032	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
COOLPGFE_00033	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
COOLPGFE_00034	3.58e-93	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
COOLPGFE_00035	1.62e-276	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
COOLPGFE_00036	9.02e-163	-	-	-	S	-	-	-	(CBS) domain
COOLPGFE_00037	5.2e-132	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
COOLPGFE_00038	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
COOLPGFE_00039	1.48e-45	yabO	-	-	J	-	-	-	S4 domain protein
COOLPGFE_00040	1.99e-78	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
COOLPGFE_00041	4.32e-80	-	-	-	J	ko:K07571	-	ko00000	S1 RNA binding domain
COOLPGFE_00042	0.0	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
COOLPGFE_00043	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
COOLPGFE_00044	2.85e-210	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
COOLPGFE_00045	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
COOLPGFE_00046	0.0	yqjE	3.4.11.14, 3.4.11.4	-	E	ko:K01258,ko:K01263	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
COOLPGFE_00047	2.57e-250	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
COOLPGFE_00048	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
COOLPGFE_00050	2.95e-72	-	-	-	T	ko:K03320	-	ko00000,ko02000	GGDEF domain
COOLPGFE_00051	1.79e-81	-	-	-	T	ko:K03320	-	ko00000,ko02000	GGDEF domain
COOLPGFE_00053	4.18e-31	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	o-acetylhomoserine
COOLPGFE_00054	3.79e-213	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
COOLPGFE_00055	3.88e-140	XK27_00160	-	-	S	-	-	-	Domain of unknown function (DUF5052)
COOLPGFE_00059	9.11e-106	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
COOLPGFE_00060	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
COOLPGFE_00063	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
COOLPGFE_00064	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
COOLPGFE_00066	7.5e-19	-	-	-	Q	-	-	-	phosphatase activity
COOLPGFE_00067	2.96e-91	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
COOLPGFE_00068	6.89e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
COOLPGFE_00069	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
COOLPGFE_00070	1.55e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
COOLPGFE_00071	3.42e-142	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
COOLPGFE_00072	6.65e-138	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
COOLPGFE_00073	1.72e-59	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
COOLPGFE_00074	2.82e-198	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
COOLPGFE_00075	1.79e-60	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
COOLPGFE_00076	3.7e-72	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
COOLPGFE_00077	3.28e-156	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
COOLPGFE_00078	8.89e-101	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
COOLPGFE_00079	9.34e-34	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
COOLPGFE_00080	1.34e-56	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
COOLPGFE_00081	1.73e-77	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
COOLPGFE_00082	5.64e-45	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
COOLPGFE_00083	1.75e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
COOLPGFE_00084	9.28e-89	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
COOLPGFE_00085	2.92e-120	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
COOLPGFE_00086	1.55e-74	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
COOLPGFE_00087	4.52e-112	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
COOLPGFE_00088	1.1e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
COOLPGFE_00089	5.15e-95	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
COOLPGFE_00090	5.33e-303	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
COOLPGFE_00091	6.92e-155	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
COOLPGFE_00092	3.13e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
COOLPGFE_00093	5.08e-74	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
COOLPGFE_00094	6.6e-83	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
COOLPGFE_00095	2.66e-220	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
COOLPGFE_00096	1.91e-81	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
COOLPGFE_00097	4.69e-199	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
COOLPGFE_00098	1.41e-207	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
COOLPGFE_00099	6.07e-182	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
COOLPGFE_00100	8.77e-194	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
COOLPGFE_00101	1.54e-101	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
COOLPGFE_00102	9.68e-86	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
COOLPGFE_00103	5.07e-61	-	-	-	-	-	-	-	-
COOLPGFE_00104	5.58e-150	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
COOLPGFE_00105	3.08e-23	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
COOLPGFE_00106	5.57e-73	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
COOLPGFE_00107	8.82e-155	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
COOLPGFE_00108	4.49e-45	-	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
COOLPGFE_00109	8.27e-78	-	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
COOLPGFE_00110	4.3e-86	-	-	-	EGP	-	-	-	Major Facilitator
COOLPGFE_00111	1.8e-119	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
COOLPGFE_00114	8.51e-286	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
COOLPGFE_00115	5.09e-224	pfoSR	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
COOLPGFE_00118	1.2e-98	oppA2	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
COOLPGFE_00119	6.54e-273	-	-	-	-	-	-	-	-
COOLPGFE_00120	3.41e-256	-	-	-	-	-	-	-	-
COOLPGFE_00121	8.01e-162	gntR1	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
COOLPGFE_00122	3.43e-284	-	-	-	M	-	-	-	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
COOLPGFE_00123	0.0	epsU	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
COOLPGFE_00124	1.19e-173	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
COOLPGFE_00125	3.56e-259	-	-	-	M	-	-	-	Glycosyl transferases group 1
COOLPGFE_00126	2.07e-173	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
COOLPGFE_00127	3.16e-194	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
COOLPGFE_00128	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
COOLPGFE_00132	1.3e-137	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
COOLPGFE_00133	1.48e-119	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
COOLPGFE_00135	1.13e-130	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
COOLPGFE_00136	6.12e-149	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
COOLPGFE_00137	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
COOLPGFE_00138	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
COOLPGFE_00139	8.06e-259	camS	-	-	S	-	-	-	sex pheromone
COOLPGFE_00140	3.99e-64	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
COOLPGFE_00141	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
COOLPGFE_00142	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
COOLPGFE_00143	5.36e-218	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
COOLPGFE_00144	1.26e-157	ybbB	-	-	S	-	-	-	Protein of unknown function (DUF1211)
COOLPGFE_00145	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
COOLPGFE_00146	3.53e-188	-	-	-	L	ko:K07448	-	ko00000,ko02048	Mrr N-terminal domain
COOLPGFE_00147	4.36e-155	-	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	Eukaryotic-type carbonic anhydrase
COOLPGFE_00148	1.31e-185	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
COOLPGFE_00149	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
COOLPGFE_00150	1.04e-45	copZ	-	-	P	-	-	-	Heavy-metal-associated domain
COOLPGFE_00151	1.99e-62	-	-	-	D	-	-	-	Di-iron-containing protein involved in the repair of iron-sulfur clusters
COOLPGFE_00152	4.47e-146	-	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
COOLPGFE_00153	1.26e-304	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
COOLPGFE_00154	1.57e-157	alkD	-	-	L	-	-	-	DNA alkylation repair enzyme
COOLPGFE_00155	1.65e-122	-	3.6.1.22	-	L	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	ko00000,ko00001,ko01000	NUDIX domain
COOLPGFE_00156	5.56e-100	-	-	-	T	-	-	-	Gaf domain
COOLPGFE_00158	1.17e-34	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
COOLPGFE_00159	2.21e-69	-	-	-	S	ko:K08987	-	ko00000	membrane
COOLPGFE_00160	3.25e-112	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	AsnC family
COOLPGFE_00161	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
COOLPGFE_00162	6.31e-68	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	transcriptional antiterminator
COOLPGFE_00163	4.6e-10	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
COOLPGFE_00164	2.13e-85	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
COOLPGFE_00165	0.0	ppc	4.1.1.31	-	H	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
COOLPGFE_00166	2.08e-71	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
COOLPGFE_00167	6.09e-122	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
COOLPGFE_00168	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
COOLPGFE_00169	7.41e-128	proP	-	-	EGP	ko:K03761,ko:K03762	-	ko00000,ko02000	Sugar (and other) transporter
COOLPGFE_00170	1.21e-56	proP	-	-	EGP	ko:K03761,ko:K03762	-	ko00000,ko02000	Sugar (and other) transporter
COOLPGFE_00172	3.11e-75	-	-	-	-	-	-	-	-
COOLPGFE_00173	9.33e-274	pmrA	-	-	EGP	ko:K08161	-	ko00000,ko02000	MFS_1 like family
COOLPGFE_00174	4.56e-154	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
COOLPGFE_00175	5.43e-183	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
COOLPGFE_00176	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
COOLPGFE_00177	2.34e-266	pepA	-	-	E	-	-	-	M42 glutamyl aminopeptidase
COOLPGFE_00178	2.02e-131	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
COOLPGFE_00180	5.48e-143	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Zeta toxin
COOLPGFE_00181	1.62e-149	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Zeta toxin
COOLPGFE_00182	9.36e-172	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
COOLPGFE_00183	1.89e-192	glnH	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
COOLPGFE_00184	3.27e-142	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
COOLPGFE_00185	4.57e-142	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
COOLPGFE_00186	1.89e-193	-	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
COOLPGFE_00187	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
COOLPGFE_00188	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
COOLPGFE_00189	1.1e-174	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
COOLPGFE_00190	1.3e-140	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
COOLPGFE_00192	1.46e-50	-	-	-	-	-	-	-	-
COOLPGFE_00193	1.6e-114	-	-	-	-	-	-	-	-
COOLPGFE_00194	7.49e-208	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
COOLPGFE_00195	3.05e-153	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
COOLPGFE_00196	6.1e-160	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
COOLPGFE_00197	2.57e-222	rihC	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
COOLPGFE_00198	3.82e-168	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
COOLPGFE_00199	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
COOLPGFE_00202	1.86e-316	yhdP	-	-	S	-	-	-	Transporter associated domain
COOLPGFE_00203	3e-133	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
COOLPGFE_00204	1.14e-292	-	-	-	E	ko:K03294	-	ko00000	amino acid
COOLPGFE_00205	1.28e-160	lys	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
COOLPGFE_00206	5.3e-283	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
COOLPGFE_00207	4.31e-313	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
COOLPGFE_00209	7.1e-234	pfoS/R	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
COOLPGFE_00210	6.91e-297	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
COOLPGFE_00211	2.15e-299	ynbB	-	-	P	-	-	-	aluminum resistance
COOLPGFE_00212	0.0	speA	4.1.1.17, 4.1.1.18, 4.1.1.19	-	E	ko:K01581,ko:K01582,ko:K01585	ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Orn/Lys/Arg decarboxylase, C-terminal domain
COOLPGFE_00214	1.13e-157	-	-	-	E	-	-	-	Amino acid permease
COOLPGFE_00215	9.03e-173	-	-	-	E	-	-	-	Amino acid permease
COOLPGFE_00216	7.82e-34	-	-	-	-	-	-	-	-
COOLPGFE_00217	5.58e-270	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
COOLPGFE_00218	5e-106	gtcA1	-	-	S	-	-	-	Teichoic acid glycosylation protein
COOLPGFE_00219	8.2e-102	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
COOLPGFE_00220	3.34e-209	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
COOLPGFE_00221	8.5e-213	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
COOLPGFE_00222	1.87e-216	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
COOLPGFE_00224	4.5e-233	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
COOLPGFE_00225	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
COOLPGFE_00226	1.89e-188	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
COOLPGFE_00227	1.75e-110	-	-	-	-	-	-	-	-
COOLPGFE_00228	2.48e-95	-	-	-	-	-	-	-	-
COOLPGFE_00229	3.06e-202	hlyX	-	-	S	ko:K03699	-	ko00000,ko02042	Transporter associated domain
COOLPGFE_00230	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
COOLPGFE_00231	9.06e-27	-	-	-	-	-	-	-	-
COOLPGFE_00232	2.16e-260	sufI	-	-	Q	-	-	-	Multicopper oxidase
COOLPGFE_00233	4.54e-59	XK27_09445	-	-	S	-	-	-	Domain of unknown function (DUF1827)
COOLPGFE_00234	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
COOLPGFE_00236	6.14e-53	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
COOLPGFE_00237	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
COOLPGFE_00238	3.22e-90	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
COOLPGFE_00239	5e-173	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
COOLPGFE_00240	4.74e-210	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
COOLPGFE_00241	3.15e-145	yjbH	-	-	Q	-	-	-	Thioredoxin
COOLPGFE_00242	4.73e-140	-	-	-	S	-	-	-	CYTH
COOLPGFE_00243	3.84e-145	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
COOLPGFE_00244	7.48e-192	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
COOLPGFE_00245	8.2e-220	rluD2	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
COOLPGFE_00246	7.7e-31	-	-	-	-	-	-	-	-
COOLPGFE_00247	3.66e-188	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
COOLPGFE_00248	2.89e-252	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
COOLPGFE_00249	1.11e-84	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
COOLPGFE_00250	5.85e-255	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
COOLPGFE_00251	2.21e-133	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
COOLPGFE_00252	1.81e-90	-	-	-	S	-	-	-	Protein of unknown function (DUF1149)
COOLPGFE_00253	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
COOLPGFE_00254	7.67e-293	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
COOLPGFE_00255	3.44e-301	ymfH	-	-	S	-	-	-	Peptidase M16
COOLPGFE_00256	1.33e-169	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
COOLPGFE_00257	8.57e-161	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
COOLPGFE_00258	1.87e-126	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
COOLPGFE_00259	1.13e-252	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
COOLPGFE_00260	6.72e-284	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
COOLPGFE_00261	1.88e-273	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
COOLPGFE_00262	2.7e-153	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
COOLPGFE_00263	1.38e-311	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
COOLPGFE_00264	1.1e-155	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
COOLPGFE_00265	2.28e-126	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
COOLPGFE_00266	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
COOLPGFE_00267	2.24e-238	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
COOLPGFE_00268	2.72e-57	-	-	-	-	-	-	-	-
COOLPGFE_00269	2.12e-222	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
COOLPGFE_00270	9.5e-201	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
COOLPGFE_00271	5.53e-242	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
COOLPGFE_00272	2.48e-224	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
COOLPGFE_00273	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
COOLPGFE_00274	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
COOLPGFE_00275	9.33e-119	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
COOLPGFE_00276	2.61e-188	dppA	-	-	E	ko:K16203	-	ko00000,ko01000,ko01002	D-aminopeptidase
COOLPGFE_00277	6.08e-107	dmpA	3.4.11.19	-	EQ	ko:K01266	-	ko00000,ko01000,ko01002	Peptidase family S58
COOLPGFE_00278	1.16e-209	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
COOLPGFE_00279	1.47e-242	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
COOLPGFE_00280	1.79e-217	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
COOLPGFE_00281	1.21e-130	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
COOLPGFE_00282	6.63e-294	-	-	-	-	-	-	-	-
COOLPGFE_00283	5.47e-47	-	-	-	-	-	-	-	-
COOLPGFE_00284	1.98e-40	ABC-SBP	-	-	S	ko:K01989,ko:K05832	-	ko00000,ko00002,ko02000	ABC transporter substrate binding protein
COOLPGFE_00285	2.35e-68	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
COOLPGFE_00286	1.89e-13	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
COOLPGFE_00287	1.08e-39	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
COOLPGFE_00288	6.81e-123	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
COOLPGFE_00289	1.38e-114	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
COOLPGFE_00290	1e-28	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
COOLPGFE_00292	6.25e-268	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
COOLPGFE_00293	4.06e-244	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
COOLPGFE_00294	2.86e-286	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
COOLPGFE_00295	3.16e-182	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
COOLPGFE_00296	2.01e-34	-	-	-	K	ko:K06977	-	ko00000	acetyltransferase
COOLPGFE_00297	4.9e-64	-	-	-	K	ko:K06977	-	ko00000	acetyltransferase
COOLPGFE_00298	3.12e-135	-	-	-	-	-	-	-	-
COOLPGFE_00299	3.86e-204	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
COOLPGFE_00300	1.77e-171	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
COOLPGFE_00301	3.84e-233	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
COOLPGFE_00302	1.13e-112	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
COOLPGFE_00303	9.43e-127	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
COOLPGFE_00304	5.08e-206	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
COOLPGFE_00305	6.4e-260	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
COOLPGFE_00306	9.32e-184	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
COOLPGFE_00307	1.71e-173	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
COOLPGFE_00308	4.19e-264	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
COOLPGFE_00309	1.1e-191	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
COOLPGFE_00310	6.44e-214	ybbR	-	-	S	-	-	-	YbbR-like protein
COOLPGFE_00311	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
COOLPGFE_00312	3.69e-190	-	-	-	S	-	-	-	hydrolase
COOLPGFE_00313	5.26e-139	-	-	-	V	-	-	-	Beta-lactamase
COOLPGFE_00314	2.1e-99	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
COOLPGFE_00315	1.3e-82	-	-	-	S	-	-	-	Cupredoxin-like domain
COOLPGFE_00316	0.0	copA	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
COOLPGFE_00317	9.05e-85	crcB1	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
COOLPGFE_00318	2.39e-78	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
COOLPGFE_00319	2.89e-160	-	-	-	-	-	-	-	-
COOLPGFE_00320	1.3e-151	-	-	-	T	-	-	-	diguanylate cyclase activity
COOLPGFE_00321	3.94e-230	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
COOLPGFE_00322	0.0	-	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
COOLPGFE_00324	3.45e-86	-	-	-	-	-	-	-	-
COOLPGFE_00325	2.62e-109	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
COOLPGFE_00326	4.25e-85	-	-	-	GM	-	-	-	epimerase
COOLPGFE_00327	0.0	-	-	-	E	-	-	-	Amino acid permease
COOLPGFE_00328	1.7e-132	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
COOLPGFE_00329	1.55e-201	-	-	-	S	-	-	-	Phospholipase, patatin family
COOLPGFE_00330	1.11e-207	psaA	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
COOLPGFE_00331	2.32e-121	-	-	-	S	-	-	-	VanZ like family
COOLPGFE_00332	1.01e-169	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
COOLPGFE_00333	3.28e-231	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
COOLPGFE_00334	5.81e-209	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
COOLPGFE_00335	2.72e-67	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
COOLPGFE_00336	6.05e-98	-	-	-	-	ko:K02246	-	ko00000,ko00002,ko02044	-
COOLPGFE_00339	2.51e-235	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
COOLPGFE_00340	4.9e-283	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
COOLPGFE_00343	7.74e-173	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
COOLPGFE_00344	0.0	yclK	-	-	T	-	-	-	Histidine kinase
COOLPGFE_00345	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
COOLPGFE_00346	1.2e-146	vanZ	-	-	V	-	-	-	VanZ like family
COOLPGFE_00347	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
COOLPGFE_00348	7.63e-112	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
COOLPGFE_00349	6.39e-227	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
COOLPGFE_00352	2.97e-244	ampC	-	-	V	-	-	-	Beta-lactamase
COOLPGFE_00353	3.69e-45	-	-	-	-	-	-	-	-
COOLPGFE_00354	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Mur ligase, middle domain
COOLPGFE_00355	8.86e-145	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
COOLPGFE_00356	2.77e-249	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
COOLPGFE_00357	5.7e-199	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
COOLPGFE_00358	9.18e-242	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
COOLPGFE_00359	3.18e-147	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
COOLPGFE_00360	9.32e-164	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
COOLPGFE_00361	7.13e-39	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
COOLPGFE_00362	6.38e-102	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
COOLPGFE_00363	2.39e-121	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
COOLPGFE_00364	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
COOLPGFE_00365	1.66e-218	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
COOLPGFE_00366	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
COOLPGFE_00367	3.63e-95	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
COOLPGFE_00368	7.57e-44	-	-	-	S	-	-	-	Protein of unknown function (DUF1146)
COOLPGFE_00369	5.61e-226	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
COOLPGFE_00370	4.4e-64	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
COOLPGFE_00371	1.04e-45	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
COOLPGFE_00372	2.41e-279	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
COOLPGFE_00373	2.07e-102	uspA	-	-	T	-	-	-	universal stress protein
COOLPGFE_00374	1.02e-56	-	-	-	-	-	-	-	-
COOLPGFE_00375	5.39e-309	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
COOLPGFE_00376	9.83e-106	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
COOLPGFE_00377	3.59e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
COOLPGFE_00378	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
COOLPGFE_00379	1.89e-275	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
COOLPGFE_00380	9.32e-293	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
COOLPGFE_00381	2.38e-167	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
COOLPGFE_00382	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
COOLPGFE_00383	1.57e-299	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
COOLPGFE_00384	2.82e-163	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
COOLPGFE_00385	5.32e-148	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
COOLPGFE_00386	9.63e-225	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
COOLPGFE_00387	5.34e-176	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
COOLPGFE_00388	1.97e-124	mreD	-	-	-	ko:K03571	-	ko00000,ko03036	-
COOLPGFE_00390	2.49e-73	-	-	-	S	-	-	-	Protein of unknown function (DUF3397)
COOLPGFE_00391	4.45e-99	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
COOLPGFE_00392	2.66e-221	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
COOLPGFE_00393	1.14e-71	ftsL	-	-	D	-	-	-	Cell division protein FtsL
COOLPGFE_00394	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
COOLPGFE_00395	4.46e-227	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
COOLPGFE_00396	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
COOLPGFE_00397	2.35e-266	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
COOLPGFE_00398	6.07e-190	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
COOLPGFE_00399	0.0	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
COOLPGFE_00400	4.25e-306	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
COOLPGFE_00401	3.21e-99	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
COOLPGFE_00402	7.21e-62	yggT	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
COOLPGFE_00403	1.14e-186	ylmH	-	-	S	-	-	-	S4 domain protein
COOLPGFE_00404	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
COOLPGFE_00405	3.24e-44	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
COOLPGFE_00406	3.66e-132	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
COOLPGFE_00407	3.72e-36	-	-	-	-	-	-	-	-
COOLPGFE_00408	1.56e-163	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
COOLPGFE_00409	3.66e-274	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
COOLPGFE_00410	2.45e-75	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
COOLPGFE_00411	3.28e-280	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
COOLPGFE_00412	7.5e-160	pgm	-	-	G	-	-	-	Phosphoglycerate mutase family
COOLPGFE_00413	3.54e-148	-	-	-	S	-	-	-	repeat protein
COOLPGFE_00414	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
COOLPGFE_00415	4.63e-316	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
COOLPGFE_00416	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
COOLPGFE_00417	3.04e-48	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
COOLPGFE_00418	8.33e-133	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
COOLPGFE_00419	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
COOLPGFE_00420	3.93e-271	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
COOLPGFE_00421	1.31e-70	ylbG	-	-	S	-	-	-	UPF0298 protein
COOLPGFE_00422	5.62e-126	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
COOLPGFE_00423	1.53e-107	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
COOLPGFE_00424	1.53e-243	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
COOLPGFE_00425	9.17e-118	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
COOLPGFE_00426	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
COOLPGFE_00427	1.5e-230	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
COOLPGFE_00428	2.09e-44	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
COOLPGFE_00429	1.01e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
COOLPGFE_00430	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
COOLPGFE_00431	5.43e-190	-	-	-	-	-	-	-	-
COOLPGFE_00432	7.85e-285	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
COOLPGFE_00433	1.35e-300	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
COOLPGFE_00434	1.83e-296	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
COOLPGFE_00435	3.33e-140	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
COOLPGFE_00436	0.0	-	-	-	I	-	-	-	Protein of unknown function (DUF2974)
COOLPGFE_00437	2.77e-08	-	-	-	-	-	-	-	-
COOLPGFE_00438	2.07e-162	pnb	-	-	C	-	-	-	nitroreductase
COOLPGFE_00440	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
COOLPGFE_00441	1.03e-84	-	-	-	-	-	-	-	-
COOLPGFE_00442	1.22e-151	-	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
COOLPGFE_00443	2.34e-242	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
COOLPGFE_00444	1.88e-116	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
COOLPGFE_00445	0.0	aha1	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
COOLPGFE_00446	7.79e-168	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
COOLPGFE_00447	6.62e-236	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
COOLPGFE_00448	1.03e-150	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
COOLPGFE_00449	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
COOLPGFE_00450	2.67e-241	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
COOLPGFE_00451	2.47e-149	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
COOLPGFE_00452	2.17e-193	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
COOLPGFE_00453	4.02e-237	-	-	-	M	-	-	-	Glycosyl transferase family 8
COOLPGFE_00454	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
COOLPGFE_00455	1.09e-128	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
COOLPGFE_00456	7.39e-65	-	-	-	-	-	-	-	-
COOLPGFE_00457	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
COOLPGFE_00458	4.68e-234	-	-	-	S	-	-	-	AAA domain
COOLPGFE_00459	8.76e-104	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
COOLPGFE_00460	3.41e-159	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
COOLPGFE_00461	1.18e-38	-	-	-	-	-	-	-	-
COOLPGFE_00462	2.88e-39	-	-	-	-	-	-	-	-
COOLPGFE_00463	5.92e-165	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
COOLPGFE_00464	1.09e-159	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
COOLPGFE_00465	2.77e-140	thiJ	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
COOLPGFE_00466	1.58e-122	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
COOLPGFE_00467	8.28e-251	ykfB	5.1.1.20	-	M	ko:K19802	-	ko00000,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
COOLPGFE_00468	1.09e-128	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase
COOLPGFE_00469	9.02e-177	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
COOLPGFE_00470	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
COOLPGFE_00471	6.17e-62	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
COOLPGFE_00472	2.07e-214	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
COOLPGFE_00473	3.01e-11	-	-	-	K	ko:K02530	-	ko00000,ko03000	DeoR C terminal sensor domain
COOLPGFE_00474	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Fumarase C C-terminus
COOLPGFE_00475	5.96e-189	-	-	-	D	-	-	-	nuclear chromosome segregation
COOLPGFE_00476	1.64e-117	-	-	-	M	-	-	-	LysM domain protein
COOLPGFE_00481	4.34e-202	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
COOLPGFE_00482	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
COOLPGFE_00486	6.92e-128	-	2.3.1.128	-	K	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
COOLPGFE_00487	5.31e-136	yiiE	-	-	S	-	-	-	Protein of unknown function (DUF1211)
COOLPGFE_00488	3.18e-34	-	-	-	-	-	-	-	-
COOLPGFE_00489	2.46e-171	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
COOLPGFE_00490	3.55e-199	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
COOLPGFE_00491	5.2e-83	-	2.7.1.211	-	G	ko:K02755,ko:K02756,ko:K02757,ko:K02777,ko:K02808,ko:K02809,ko:K02810	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
COOLPGFE_00492	9.39e-256	-	2.7.1.11, 2.7.1.90	-	F	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
COOLPGFE_00493	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
COOLPGFE_00494	8.19e-63	malZ	3.2.1.20, 3.2.1.41	CBM48,GH13,GH31	G	ko:K01187,ko:K01200	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
COOLPGFE_00495	8.86e-82	malZ	3.2.1.20, 3.2.1.41	CBM48,GH13,GH31	G	ko:K01187,ko:K01200	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
COOLPGFE_00496	5.94e-99	malZ	3.2.1.20, 3.2.1.41	CBM48,GH13,GH31	G	ko:K01187,ko:K01200	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
COOLPGFE_00497	0.0	speA	4.1.1.17, 4.1.1.18, 4.1.1.19	-	E	ko:K01581,ko:K01582,ko:K01585	ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Orn/Lys/Arg decarboxylase, C-terminal domain
COOLPGFE_00498	0.0	-	-	-	E	-	-	-	Amino acid permease
COOLPGFE_00499	2.78e-142	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
COOLPGFE_00500	7.9e-259	-	-	-	G	-	-	-	Major Facilitator Superfamily
COOLPGFE_00501	3.21e-48	-	-	-	L	ko:K07497	-	ko00000	COG2963 Transposase and inactivated derivatives
COOLPGFE_00502	2.57e-262	-	-	-	G	-	-	-	Major Facilitator Superfamily
COOLPGFE_00503	1.23e-255	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
COOLPGFE_00505	3.24e-251	malS	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Glycogen debranching enzyme, glucanotransferase domain
COOLPGFE_00506	1.51e-25	malS	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Glycogen debranching enzyme, glucanotransferase domain
COOLPGFE_00507	2.42e-282	oxlT	-	-	P	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
COOLPGFE_00510	3.39e-63	-	-	-	-	-	-	-	-
COOLPGFE_00511	0.0	-	-	-	L	-	-	-	Helicase conserved C-terminal domain
COOLPGFE_00512	1.42e-119	-	-	-	L	-	-	-	Helicase conserved C-terminal domain
COOLPGFE_00513	1.36e-242	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
COOLPGFE_00516	1.16e-207	-	3.4.14.13	-	M	ko:K20742	-	ko00000,ko01000,ko01002	NlpC/P60 family
COOLPGFE_00517	4.66e-312	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
COOLPGFE_00518	5.33e-08	-	-	-	-	-	-	-	-
COOLPGFE_00519	5.52e-82	-	-	-	S	-	-	-	Domain of unknown function (DUF956)
COOLPGFE_00520	7.29e-214	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
COOLPGFE_00521	5.16e-181	manY	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
COOLPGFE_00522	5.49e-238	manL	2.7.1.191	-	G	ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
COOLPGFE_00524	1.79e-72	-	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
COOLPGFE_00525	6.87e-311	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
COOLPGFE_00526	1.15e-71	-	-	-	C	-	-	-	FAD binding domain
COOLPGFE_00527	7.85e-119	-	-	-	C	-	-	-	FAD binding domain
COOLPGFE_00528	6.74e-07	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	domain protein
COOLPGFE_00529	5.44e-14	-	-	-	K	-	-	-	LysR substrate binding domain
COOLPGFE_00530	2.43e-52	-	-	-	K	-	-	-	LysR substrate binding domain
COOLPGFE_00531	2.36e-283	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
COOLPGFE_00532	4.75e-215	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
COOLPGFE_00533	9.19e-98	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
COOLPGFE_00534	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
COOLPGFE_00535	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
COOLPGFE_00536	8.88e-103	-	-	-	GM	-	-	-	NmrA-like family
COOLPGFE_00537	4.6e-119	-	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
COOLPGFE_00538	1.73e-97	-	-	-	S	ko:K07126	-	ko00000	Sel1-like repeats.
COOLPGFE_00539	3.6e-266	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
COOLPGFE_00540	2.97e-266	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
COOLPGFE_00541	2.49e-255	xerS	-	-	L	ko:K03733	-	ko00000,ko03036	Belongs to the 'phage' integrase family
COOLPGFE_00542	1.93e-259	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
COOLPGFE_00543	2.95e-124	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
COOLPGFE_00544	3.3e-115	yfhC	-	-	C	-	-	-	Nitroreductase family
COOLPGFE_00545	3.62e-41	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
COOLPGFE_00546	3.88e-147	pgm1	-	-	G	-	-	-	phosphoglycerate mutase
COOLPGFE_00547	8.46e-71	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
COOLPGFE_00548	3.21e-144	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
COOLPGFE_00549	3.14e-110	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
COOLPGFE_00550	1.59e-154	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
COOLPGFE_00551	7.87e-213	-	-	-	EG	-	-	-	EamA-like transporter family
COOLPGFE_00552	8.74e-239	-	-	-	-	-	-	-	-
COOLPGFE_00553	1.7e-202	-	-	-	S	-	-	-	EDD domain protein, DegV family
COOLPGFE_00554	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
COOLPGFE_00555	1.39e-313	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
COOLPGFE_00556	4.02e-58	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
COOLPGFE_00557	0.0	carB1	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
COOLPGFE_00558	1.88e-251	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
COOLPGFE_00559	1.95e-218	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
COOLPGFE_00560	1.3e-99	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
COOLPGFE_00561	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
COOLPGFE_00562	1.28e-77	-	-	-	-	-	-	-	-
COOLPGFE_00563	2.42e-238	XK27_01810	-	-	S	-	-	-	Calcineurin-like phosphoesterase
COOLPGFE_00564	2.29e-275	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
COOLPGFE_00565	5.35e-85	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
COOLPGFE_00566	2.12e-136	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
COOLPGFE_00567	6.44e-152	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
COOLPGFE_00568	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
COOLPGFE_00569	0.0	yuxL	3.4.19.1	-	E	ko:K01303	-	ko00000,ko01000,ko01002	Prolyl oligopeptidase family
COOLPGFE_00570	5.32e-242	-	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
COOLPGFE_00571	3.26e-78	-	-	-	I	-	-	-	acetylesterase activity
COOLPGFE_00572	5.21e-91	-	-	-	I	-	-	-	Psort location Cytoplasmic, score
COOLPGFE_00573	4.33e-192	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
COOLPGFE_00574	4.71e-149	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
COOLPGFE_00575	1.24e-147	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
COOLPGFE_00576	1.45e-152	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
COOLPGFE_00577	4.73e-65	-	-	-	S	-	-	-	SLAP domain
COOLPGFE_00578	1.96e-136	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
COOLPGFE_00580	2.7e-243	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
COOLPGFE_00581	1.74e-107	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
COOLPGFE_00583	5.11e-18	-	-	-	C	-	-	-	Pyridoxamine 5'-phosphate oxidase
COOLPGFE_00584	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
COOLPGFE_00585	2.02e-168	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
COOLPGFE_00586	2.88e-92	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Low molecular weight phosphotyrosine protein phosphatase
COOLPGFE_00587	2.73e-98	-	-	-	-	-	-	-	-
COOLPGFE_00588	2.44e-66	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
COOLPGFE_00589	1.09e-120	cylB	-	-	U	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
COOLPGFE_00590	1.74e-136	-	-	-	L	-	-	-	Integrase
COOLPGFE_00591	6.4e-93	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
COOLPGFE_00592	1.01e-95	-	-	-	K	-	-	-	3.5.2 Transcription regulation
COOLPGFE_00593	1.22e-275	-	-	-	V	-	-	-	MATE efflux family protein
COOLPGFE_00594	1.38e-49	-	-	-	T	-	-	-	diguanylate cyclase activity
COOLPGFE_00595	3.15e-245	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
COOLPGFE_00596	0.0	carB	-	-	F	-	-	-	Psort location Cytoplasmic, score 8.87
COOLPGFE_00597	3.38e-62	-	-	-	V	ko:K06147	-	ko00000,ko02000	(ABC) transporter
COOLPGFE_00598	3.75e-92	ybaJ	-	-	Q	-	-	-	Hypothetical methyltransferase
COOLPGFE_00599	7.57e-10	-	-	-	Q	-	-	-	Methyltransferase domain
COOLPGFE_00600	3.6e-280	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
COOLPGFE_00601	1.09e-61	-	-	-	E	-	-	-	transmembrane transport
COOLPGFE_00602	9.35e-161	WQ51_05710	-	-	S	-	-	-	Mitochondrial biogenesis AIM24
COOLPGFE_00603	3.33e-97	-	-	-	K	-	-	-	Transcriptional regulator
COOLPGFE_00604	1.12e-58	-	-	-	-	-	-	-	-
COOLPGFE_00608	0.0	-	-	-	D	-	-	-	Putative exonuclease SbcCD, C subunit
COOLPGFE_00609	1.73e-76	-	-	-	-	-	-	-	-
COOLPGFE_00610	2.87e-119	-	-	-	S	ko:K06889	-	ko00000	Hydrolases of the alpha beta superfamily
COOLPGFE_00611	1.63e-146	ylbE	-	-	GM	-	-	-	NAD(P)H-binding
COOLPGFE_00612	6.38e-61	-	-	-	V	ko:K06147	-	ko00000,ko02000	(ABC) transporter
COOLPGFE_00613	1.07e-213	-	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
COOLPGFE_00614	2.67e-101	-	-	-	V	ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score
COOLPGFE_00615	1.13e-223	gyaR	1.1.1.26, 1.1.1.399, 1.1.1.95	-	CH	ko:K00015,ko:K00058	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
COOLPGFE_00616	8.42e-102	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
COOLPGFE_00617	0.0	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
COOLPGFE_00618	0.0	XK27_09605	-	-	V	ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter transmembrane region
COOLPGFE_00619	4.63e-68	XK27_05625	-	-	P	-	-	-	Rhodanese Homology Domain
COOLPGFE_00620	5.09e-89	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA-DNA hybrid ribonuclease activity
COOLPGFE_00621	1.69e-145	-	-	-	L	-	-	-	Resolvase, N-terminal
COOLPGFE_00622	4.63e-98	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
COOLPGFE_00624	9.05e-55	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
COOLPGFE_00625	5.02e-168	-	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD-hyrolase-like
COOLPGFE_00626	4.66e-93	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
COOLPGFE_00627	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
COOLPGFE_00628	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
COOLPGFE_00629	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
COOLPGFE_00630	7.03e-216	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	GHMP kinases N terminal domain
COOLPGFE_00631	1.22e-224	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
COOLPGFE_00632	3.3e-261	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
COOLPGFE_00633	2.27e-247	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
COOLPGFE_00634	2.02e-219	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
COOLPGFE_00635	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
COOLPGFE_00636	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
COOLPGFE_00637	1.1e-144	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
COOLPGFE_00638	3.09e-56	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
COOLPGFE_00639	3.64e-154	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
COOLPGFE_00640	1.88e-75	-	-	-	V	ko:K06147	-	ko00000,ko02000	abc transporter atp-binding protein
COOLPGFE_00641	3.51e-47	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
COOLPGFE_00642	4.65e-08	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
COOLPGFE_00643	7.52e-47	-	-	-	V	ko:K06147	-	ko00000,ko02000	(ABC) transporter
COOLPGFE_00644	1.6e-12	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
COOLPGFE_00645	1.76e-191	-	-	-	G	-	-	-	Sucrose-6F-phosphate phosphohydrolase
COOLPGFE_00646	2.98e-135	-	-	-	-	-	-	-	-
COOLPGFE_00647	1.88e-197	-	-	-	T	-	-	-	diguanylate cyclase
COOLPGFE_00648	1.34e-286	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
COOLPGFE_00650	1.43e-135	-	-	-	T	ko:K16923	-	ko00000,ko00002,ko02000	phosphorelay sensor kinase activity
COOLPGFE_00651	1.73e-173	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
COOLPGFE_00652	4.3e-190	-	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
COOLPGFE_00653	2.21e-179	-	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
COOLPGFE_00654	3.03e-53	-	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
COOLPGFE_00655	5.43e-133	M1-740	-	-	I	-	-	-	NUDIX domain
COOLPGFE_00656	2.26e-243	-	-	-	S	-	-	-	Glycosyl hydrolases family 18
COOLPGFE_00657	3.17e-156	-	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
COOLPGFE_00659	5.81e-73	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
COOLPGFE_00660	5.46e-10	-	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter, ATP-binding protein
COOLPGFE_00661	0.000856	ccmA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
COOLPGFE_00662	2.71e-28	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
COOLPGFE_00663	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
COOLPGFE_00664	2.5e-161	phoB	-	-	T	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
COOLPGFE_00665	1.98e-147	-	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
COOLPGFE_00666	9.06e-182	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
COOLPGFE_00667	2.41e-201	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
COOLPGFE_00668	5.27e-206	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
COOLPGFE_00669	8.71e-201	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
COOLPGFE_00672	1.44e-160	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
COOLPGFE_00673	2.26e-49	-	-	-	-	-	-	-	-
COOLPGFE_00674	1.26e-98	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
COOLPGFE_00675	6.48e-140	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
COOLPGFE_00677	5.35e-81	-	-	-	S	ko:K07006	-	ko00000	Pyridoxamine 5'-phosphate oxidase
COOLPGFE_00681	3.52e-106	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
COOLPGFE_00682	3.03e-238	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
COOLPGFE_00683	3.05e-191	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
COOLPGFE_00684	3.96e-183	yycI	-	-	S	-	-	-	YycH protein
COOLPGFE_00685	1.6e-316	yycH	-	-	S	-	-	-	YycH protein
COOLPGFE_00686	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
COOLPGFE_00687	2.21e-168	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
COOLPGFE_00689	3.19e-194	-	-	-	I	-	-	-	Acyl-transferase
COOLPGFE_00690	1.25e-199	arbx	-	-	M	-	-	-	Glycosyl transferase family 8
COOLPGFE_00691	9.6e-149	-	-	-	M	-	-	-	Glycosyl transferase family 8
COOLPGFE_00692	9.24e-213	arbZ	-	-	I	-	-	-	Phosphate acyltransferases
COOLPGFE_00693	7.52e-24	-	-	-	-	-	-	-	-
COOLPGFE_00694	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
COOLPGFE_00695	6.06e-222	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
COOLPGFE_00696	5.86e-191	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
COOLPGFE_00697	3.15e-126	-	-	-	S	-	-	-	Membrane
COOLPGFE_00698	2.73e-282	-	-	-	EGP	ko:K08196	-	ko00000,ko02000	Major Facilitator
COOLPGFE_00699	4.37e-212	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
COOLPGFE_00700	3.78e-220	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
COOLPGFE_00702	2.71e-49	metK1	-	-	E	-	-	-	methionine synthase, vitamin-B12 independent
COOLPGFE_00703	4.93e-197	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
COOLPGFE_00704	4.04e-208	cpsY	-	-	K	-	-	-	Transcriptional regulator, LysR family
COOLPGFE_00705	1.5e-166	-	-	-	-	-	-	-	-
COOLPGFE_00706	3.97e-14	mutS1	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
COOLPGFE_00707	0.0	mutS1	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
COOLPGFE_00708	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
COOLPGFE_00709	1.69e-16	-	1.3.8.1, 1.3.8.7	-	I	ko:K00248,ko:K00249,ko:K18244	ko00071,ko00280,ko00410,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map00650,map01100,map01110,map01120,map01130,map01200,map01212,map03320	ko00000,ko00001,ko00002,ko01000	Acyl-CoA dehydrogenase, C-terminal domain
COOLPGFE_00710	2.28e-96	-	-	-	L	-	-	-	DDE superfamily endonuclease
COOLPGFE_00711	1e-93	thgA3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
COOLPGFE_00712	2.11e-69	-	-	-	S	-	-	-	Alpha beta hydrolase
COOLPGFE_00713	4.73e-206	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
COOLPGFE_00714	1.37e-133	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
COOLPGFE_00715	3.04e-32	-	-	-	-	-	-	-	-
COOLPGFE_00716	2.75e-309	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
COOLPGFE_00717	2.24e-193	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
COOLPGFE_00718	3.39e-157	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
COOLPGFE_00719	8.58e-103	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
COOLPGFE_00720	1.49e-187	-	-	-	S	-	-	-	Peptidase family M23
COOLPGFE_00721	8.73e-70	ogt	2.1.1.63	-	L	ko:K00567,ko:K13531	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
COOLPGFE_00722	1.79e-108	yeeC	-	-	P	-	-	-	T5orf172
COOLPGFE_00723	1.85e-27	yeeC	-	-	P	-	-	-	T5orf172
COOLPGFE_00724	1.26e-216	-	-	-	V	ko:K19147	-	ko00000,ko02048	McrBC 5-methylcytosine restriction system component
COOLPGFE_00725	0.0	-	-	-	V	ko:K07452	-	ko00000,ko01000,ko02048	AAA domain (dynein-related subfamily)
COOLPGFE_00727	1.23e-34	-	-	-	-	-	-	-	-
COOLPGFE_00728	3.14e-72	-	-	-	-	-	-	-	-
COOLPGFE_00729	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
COOLPGFE_00730	2.72e-65	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
COOLPGFE_00731	3.89e-227	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
COOLPGFE_00732	7.89e-30	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
COOLPGFE_00733	1.31e-311	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
COOLPGFE_00734	1.68e-239	-	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
COOLPGFE_00735	1.47e-49	mdt(A)	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
COOLPGFE_00736	0.0	copB	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
COOLPGFE_00737	1.41e-33	-	-	-	L	-	-	-	DDE superfamily endonuclease
COOLPGFE_00738	3.78e-20	-	-	-	S	-	-	-	Gram-negative-bacterium-type cell wall biogenesis
COOLPGFE_00739	7.36e-139	pat	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
COOLPGFE_00740	9.38e-97	-	-	-	C	-	-	-	FMN_bind
COOLPGFE_00741	4.98e-12	-	-	-	D	-	-	-	Filamentation induced by cAMP protein fic
COOLPGFE_00743	9.12e-201	-	-	-	V	-	-	-	LD-carboxypeptidase
COOLPGFE_00744	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
COOLPGFE_00745	1.73e-222	-	-	-	-	-	-	-	-
COOLPGFE_00746	1.76e-176	-	-	-	-	-	-	-	-
COOLPGFE_00747	2.49e-35	-	-	-	-	-	-	-	-
COOLPGFE_00748	3.33e-146	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
COOLPGFE_00749	4.14e-177	prsW	-	-	S	-	-	-	Involved in the degradation of specific anti-sigma factors
COOLPGFE_00750	4.22e-131	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
COOLPGFE_00751	2.63e-44	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
COOLPGFE_00752	0.0	gapN	1.2.1.9	-	C	ko:K00131	ko00010,ko00030,ko01100,ko01120,ko01200,map00010,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
COOLPGFE_00753	0.0	-	-	-	EM	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
COOLPGFE_00754	3.49e-218	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
COOLPGFE_00755	4.87e-101	ywnA	-	-	K	-	-	-	Transcriptional regulator
COOLPGFE_00756	5.95e-19	-	-	-	GM	-	-	-	NAD(P)H-binding
COOLPGFE_00757	3.83e-120	-	-	-	GM	-	-	-	NmrA-like family
COOLPGFE_00758	5.31e-211	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Peptidase family M48
COOLPGFE_00759	5.58e-55	-	-	-	-	-	-	-	-
COOLPGFE_00760	1.08e-288	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
COOLPGFE_00761	0.0	prtP	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
COOLPGFE_00762	7.54e-99	-	-	-	K	-	-	-	GNAT family
COOLPGFE_00763	1.27e-62	-	-	-	-	-	-	-	-
COOLPGFE_00764	4.3e-36	-	-	-	-	-	-	-	-
COOLPGFE_00765	1.32e-09	apl	3.1.3.1	-	S	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	SNARE associated Golgi protein
COOLPGFE_00766	5.84e-253	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
COOLPGFE_00767	3.13e-252	-	-	-	-	-	-	-	-
COOLPGFE_00768	1.24e-230	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
COOLPGFE_00769	6.12e-102	-	-	-	S	-	-	-	Helix-turn-helix domain
COOLPGFE_00770	4.8e-128	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
COOLPGFE_00771	1.01e-220	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
COOLPGFE_00772	4.26e-133	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
COOLPGFE_00773	1.17e-96	-	-	-	K	-	-	-	LytTr DNA-binding domain
COOLPGFE_00775	2.48e-92	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
COOLPGFE_00776	1.11e-62	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
COOLPGFE_00777	2.78e-55	-	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
COOLPGFE_00778	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
COOLPGFE_00779	2.58e-147	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
COOLPGFE_00780	1.58e-160	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
COOLPGFE_00781	1.35e-172	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
COOLPGFE_00783	0.0	-	3.1.4.46, 3.2.1.99	GH43	N	ko:K01126,ko:K06113	ko00564,map00564	ko00000,ko00001,ko01000	domain, Protein
COOLPGFE_00784	1.5e-16	-	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphodiester phosphodiesterase activity
COOLPGFE_00786	1.49e-149	-	-	-	L	-	-	-	DNA synthesis involved in DNA repair
COOLPGFE_00787	6.16e-21	-	-	-	L	-	-	-	DNA synthesis involved in DNA repair
COOLPGFE_00788	3.68e-73	-	-	-	L	-	-	-	DNA synthesis involved in DNA repair
COOLPGFE_00789	1.01e-165	-	-	-	S	-	-	-	VanZ like family
COOLPGFE_00790	3.27e-96	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
COOLPGFE_00791	1.59e-104	-	-	-	-	-	-	-	-
COOLPGFE_00792	7.85e-12	-	-	-	M	-	-	-	NlpC/P60 family
COOLPGFE_00793	1.81e-112	-	-	-	M	-	-	-	NlpC/P60 family
COOLPGFE_00795	1.85e-170	-	-	-	G	-	-	-	Peptidase_C39 like family
COOLPGFE_00796	6.03e-248	-	-	-	S	-	-	-	Acyltransferase family
COOLPGFE_00799	1.98e-279	-	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyl transferase 4-like domain
COOLPGFE_00800	1.06e-256	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
COOLPGFE_00801	7.66e-228	mprF	-	-	S	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
COOLPGFE_00802	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
COOLPGFE_00803	1.3e-40	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
COOLPGFE_00804	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
COOLPGFE_00805	5.92e-102	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
COOLPGFE_00808	5e-275	-	-	-	S	-	-	-	FtsX-like permease family
COOLPGFE_00809	2.2e-151	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
COOLPGFE_00811	6.69e-20	malH	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase C-terminal domain
COOLPGFE_00812	3.71e-265	malH	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase C-terminal domain
COOLPGFE_00813	3.95e-50	glvC	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
COOLPGFE_00814	9.11e-118	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
COOLPGFE_00815	1.14e-183	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
COOLPGFE_00816	2.93e-280	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
COOLPGFE_00817	8.85e-286	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
COOLPGFE_00818	2.66e-97	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
COOLPGFE_00819	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
COOLPGFE_00820	4.12e-104	cydD1	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	abc transporter atp-binding protein
COOLPGFE_00823	1.13e-40	bgl	3.2.1.21, 3.2.1.86	GT1	G	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	beta-glucosidase activity
COOLPGFE_00824	6.46e-242	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
COOLPGFE_00825	8.83e-39	scrK	2.7.1.2, 2.7.1.4	-	GK	ko:K00845,ko:K00847	ko00010,ko00051,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00051,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
COOLPGFE_00827	4.13e-179	-	-	-	-	-	-	-	-
COOLPGFE_00829	1.81e-109	-	-	-	K	-	-	-	DNA-templated transcription, initiation
COOLPGFE_00830	3.41e-171	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
COOLPGFE_00831	2.19e-186	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Sucrose glucosyltransferase
COOLPGFE_00832	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
COOLPGFE_00833	6.42e-229	yfdH	-	GT2	M	ko:K12999,ko:K20534	-	ko00000,ko01000,ko01003,ko01005,ko02000	Glycosyltransferase like family 2
COOLPGFE_00834	6.41e-118	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
COOLPGFE_00835	6.89e-188	yitS	-	-	S	-	-	-	EDD domain protein, DegV family
COOLPGFE_00836	1.62e-133	-	-	-	T	-	-	-	EAL domain
COOLPGFE_00837	3.76e-134	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
COOLPGFE_00838	1.92e-161	pgm7	-	-	G	-	-	-	Phosphoglycerate mutase family
COOLPGFE_00839	4.69e-17	-	-	-	-	-	-	-	-
COOLPGFE_00840	3.19e-150	-	-	-	-	-	-	-	-
COOLPGFE_00841	1.6e-115	-	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	biotin transmembrane transporter activity
COOLPGFE_00842	2.22e-312	-	-	-	EGP	-	-	-	Major Facilitator
COOLPGFE_00843	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
COOLPGFE_00845	0.0	traI	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
COOLPGFE_00846	0.0	-	-	-	S	-	-	-	SH3-like domain
COOLPGFE_00847	2.64e-139	-	-	-	-	-	-	-	-
COOLPGFE_00848	3.91e-106	-	-	-	-	-	-	-	-
COOLPGFE_00849	1.61e-126	-	-	-	P	-	-	-	nitrite transmembrane transporter activity
COOLPGFE_00850	1.63e-67	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
COOLPGFE_00851	1.66e-55	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2087)
COOLPGFE_00852	1.42e-107	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
COOLPGFE_00853	1.94e-270	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
COOLPGFE_00854	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
COOLPGFE_00855	5.04e-173	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
COOLPGFE_00856	8.7e-52	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
COOLPGFE_00857	1.98e-162	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
COOLPGFE_00858	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
COOLPGFE_00859	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
COOLPGFE_00860	9.71e-253	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
COOLPGFE_00861	1.17e-141	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
COOLPGFE_00862	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
COOLPGFE_00863	1.13e-308	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
COOLPGFE_00864	1.57e-68	livF	-	-	E	ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
COOLPGFE_00865	1.1e-119	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
COOLPGFE_00866	9.71e-68	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
COOLPGFE_00867	5.61e-65	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
COOLPGFE_00868	3.79e-64	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
COOLPGFE_00869	5.66e-257	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
COOLPGFE_00870	8.59e-133	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
COOLPGFE_00871	6.3e-95	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
COOLPGFE_00872	7.64e-88	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
COOLPGFE_00873	1.07e-196	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
COOLPGFE_00874	0.0	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
COOLPGFE_00875	2.38e-43	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
COOLPGFE_00876	1.16e-206	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
COOLPGFE_00877	5.49e-197	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
COOLPGFE_00878	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
COOLPGFE_00879	5.85e-12	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	transmembrane transport
COOLPGFE_00880	3.95e-29	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	transmembrane transport
COOLPGFE_00881	6.57e-19	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
COOLPGFE_00882	3.94e-45	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	transmembrane transport
COOLPGFE_00883	1.75e-67	-	-	-	-	-	-	-	-
COOLPGFE_00884	2.84e-143	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
COOLPGFE_00885	1.28e-45	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
COOLPGFE_00886	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
COOLPGFE_00887	3e-223	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
COOLPGFE_00888	6.32e-310	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
COOLPGFE_00889	3.83e-178	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
COOLPGFE_00890	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
COOLPGFE_00891	2.01e-212	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
COOLPGFE_00892	1.76e-162	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
COOLPGFE_00896	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
COOLPGFE_00897	3.26e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
COOLPGFE_00898	1.67e-74	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
COOLPGFE_00899	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
COOLPGFE_00900	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
COOLPGFE_00901	9.78e-232	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
COOLPGFE_00902	1.31e-48	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
COOLPGFE_00903	3.75e-242	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
COOLPGFE_00904	3.53e-228	oppF	-	-	P	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
COOLPGFE_00905	2.21e-227	oppB	-	-	P	ko:K02033,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
COOLPGFE_00906	4.18e-208	oppC5	-	-	P	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
COOLPGFE_00907	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
COOLPGFE_00908	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
COOLPGFE_00909	2.5e-164	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
COOLPGFE_00910	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
COOLPGFE_00911	1.71e-219	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
COOLPGFE_00912	4.93e-09	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
COOLPGFE_00913	5.31e-22	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
COOLPGFE_00914	5.23e-96	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
COOLPGFE_00915	5.53e-96	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
COOLPGFE_00916	2.27e-71	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
COOLPGFE_00917	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
COOLPGFE_00918	3.93e-59	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
COOLPGFE_00919	7.02e-119	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
COOLPGFE_00920	2.41e-178	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
COOLPGFE_00922	0.0	snf	-	-	KL	-	-	-	domain protein
COOLPGFE_00923	4.71e-74	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
COOLPGFE_00924	0.0	XK27_00340	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
COOLPGFE_00925	0.0	-	-	-	S	-	-	-	TerB-C domain
COOLPGFE_00926	1.23e-315	-	-	-	P	-	-	-	P-loop Domain of unknown function (DUF2791)
COOLPGFE_00927	0.0	-	-	-	L	ko:K03724	-	ko00000,ko01000,ko03400	DEAD DEAH box helicase
COOLPGFE_00928	1.98e-123	-	-	-	-	-	-	-	-
COOLPGFE_00929	2.59e-192	glnH	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
COOLPGFE_00930	1.68e-192	-	-	-	U	ko:K05340	-	ko00000,ko02000	ribose uptake protein RbsU
COOLPGFE_00931	2.53e-147	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
COOLPGFE_00932	6.52e-43	ynzC	-	-	S	-	-	-	UPF0291 protein
COOLPGFE_00933	1.55e-42	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
COOLPGFE_00934	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
COOLPGFE_00935	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
COOLPGFE_00936	1.05e-93	pheB	5.4.99.5	-	S	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the UPF0735 family
COOLPGFE_00937	2.28e-270	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
COOLPGFE_00938	0.0	-	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
COOLPGFE_00939	5.05e-233	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
COOLPGFE_00940	1.31e-148	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
COOLPGFE_00941	1.41e-243	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
COOLPGFE_00942	1.49e-176	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
COOLPGFE_00943	3.29e-236	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
COOLPGFE_00944	5.02e-169	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
COOLPGFE_00945	2.75e-118	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
COOLPGFE_00946	3.99e-176	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
COOLPGFE_00947	1.97e-187	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
COOLPGFE_00948	6.52e-289	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
COOLPGFE_00949	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
COOLPGFE_00950	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
COOLPGFE_00951	1.01e-109	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
COOLPGFE_00952	1.58e-263	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
COOLPGFE_00953	1.03e-57	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
COOLPGFE_00954	1.02e-56	ylxQ	-	-	J	-	-	-	ribosomal protein
COOLPGFE_00955	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
COOLPGFE_00956	2.57e-78	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
COOLPGFE_00957	1.31e-213	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
COOLPGFE_00958	1.35e-51	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Bacterial transferase hexapeptide (six repeats)
COOLPGFE_00959	5.94e-271	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
COOLPGFE_00960	5.16e-218	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
COOLPGFE_00961	2.49e-114	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
COOLPGFE_00962	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
COOLPGFE_00963	1.18e-128	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
COOLPGFE_00964	6.61e-228	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
COOLPGFE_00965	3.09e-244	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
COOLPGFE_00966	1.04e-109	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
COOLPGFE_00967	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
COOLPGFE_00968	3.9e-235	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
COOLPGFE_00969	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
COOLPGFE_00970	2.47e-156	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
COOLPGFE_00971	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
COOLPGFE_00972	2.82e-122	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
COOLPGFE_00973	5.47e-66	-	-	-	K	-	-	-	DNA-binding transcription factor activity
COOLPGFE_00974	3.83e-200	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
COOLPGFE_00975	1.39e-257	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
COOLPGFE_00976	4.84e-242	-	-	-	S	-	-	-	AI-2E family transporter
COOLPGFE_00977	3.67e-147	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
COOLPGFE_00978	0.0	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
COOLPGFE_00979	4.37e-205	lysR5	-	-	K	-	-	-	LysR substrate binding domain
COOLPGFE_00980	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
COOLPGFE_00981	1.97e-173	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
COOLPGFE_00982	5.93e-135	-	-	-	S	-	-	-	Protein of unknown function (DUF4230)
COOLPGFE_00983	4.04e-222	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF898)
COOLPGFE_00984	9.52e-72	-	-	-	S	-	-	-	Protein of unknown function (DUF2752)
COOLPGFE_00985	9.3e-310	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
COOLPGFE_00986	1.06e-193	-	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
COOLPGFE_00987	1.52e-129	-	-	-	I	-	-	-	PAP2 superfamily
COOLPGFE_00988	6.72e-204	-	-	-	-	-	-	-	-
COOLPGFE_00989	1.79e-212	-	-	-	K	-	-	-	LysR substrate binding domain
COOLPGFE_00990	0.0	yfiB1	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter, ATP-binding protein
COOLPGFE_00991	1.39e-180	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
COOLPGFE_00992	4.06e-215	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
COOLPGFE_00996	5.15e-216	XK27_10395	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
COOLPGFE_00997	1.02e-280	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
COOLPGFE_00998	6.6e-150	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
COOLPGFE_00999	5.28e-200	degV3	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
COOLPGFE_01000	9.85e-49	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
COOLPGFE_01001	4.39e-210	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
COOLPGFE_01002	9.33e-177	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
COOLPGFE_01003	8.75e-198	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
COOLPGFE_01004	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
COOLPGFE_01005	3.79e-316	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
COOLPGFE_01006	1.65e-210	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Phage integrase, N-terminal SAM-like domain
COOLPGFE_01007	7.14e-117	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
COOLPGFE_01008	1.58e-314	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
COOLPGFE_01009	1.13e-223	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
COOLPGFE_01012	9.27e-96	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
COOLPGFE_01013	1.28e-184	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
COOLPGFE_01014	1.04e-288	aspC	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
COOLPGFE_01015	7.78e-11	secY2	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	SecY translocase
COOLPGFE_01017	3.6e-209	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
COOLPGFE_01019	3.99e-197	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
COOLPGFE_01020	4.83e-30	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
COOLPGFE_01021	3.92e-219	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
COOLPGFE_01022	1.46e-128	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
COOLPGFE_01023	4.68e-99	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
COOLPGFE_01024	9.98e-215	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
COOLPGFE_01025	7.11e-173	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
COOLPGFE_01026	2.59e-227	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
COOLPGFE_01027	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
COOLPGFE_01028	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
COOLPGFE_01029	1.49e-254	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
COOLPGFE_01030	1.69e-256	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
COOLPGFE_01031	7.44e-258	-	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
COOLPGFE_01032	3.25e-48	pbg4	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
COOLPGFE_01033	5e-57	celA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	beta-glucosidase activity
COOLPGFE_01034	1.85e-57	-	-	-	L	-	-	-	DDE superfamily endonuclease
COOLPGFE_01035	6.73e-72	luxA_2	-	-	C	-	-	-	Coenzyme F420-dependent N5N10-methylene tetrahydromethanopterin reductase
COOLPGFE_01036	1.46e-56	-	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
COOLPGFE_01037	1.06e-234	-	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Rossmann-like domain
COOLPGFE_01038	1.33e-75	-	-	-	K	-	-	-	sequence-specific DNA binding
COOLPGFE_01039	1.15e-33	-	-	-	-	-	-	-	-
COOLPGFE_01040	3.12e-50	-	-	-	-	-	-	-	-
COOLPGFE_01041	9.97e-98	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
COOLPGFE_01043	2.69e-255	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
COOLPGFE_01045	2.19e-152	rfbP	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
COOLPGFE_01046	7.21e-191	cps3J	-	-	M	-	-	-	Domain of unknown function (DUF4422)
COOLPGFE_01047	1.69e-280	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
COOLPGFE_01048	5.38e-219	-	-	-	S	ko:K07011	-	ko00000	Glycosyltransferase like family 2
COOLPGFE_01049	1.59e-233	epsF	-	GT4	M	ko:K19424	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
COOLPGFE_01050	4.81e-253	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
COOLPGFE_01051	0.0	epsIIL	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
COOLPGFE_01052	1.39e-231	licD	-	-	M	ko:K07271	-	ko00000,ko01000	LicD family
COOLPGFE_01053	3.17e-111	tagD	2.7.7.15, 2.7.7.39	-	IM	ko:K00968,ko:K00980	ko00440,ko00564,ko01100,ko05231,map00440,map00564,map01100,map05231	ko00000,ko00001,ko00002,ko01000	Glycerol-3-phosphate cytidylyltransferase
COOLPGFE_01054	1.12e-287	-	-	-	-	-	-	-	-
COOLPGFE_01056	3.53e-35	XK27_02085	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
COOLPGFE_01057	2.77e-131	-	-	-	L	-	-	-	nuclease
COOLPGFE_01058	2.7e-198	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
COOLPGFE_01059	8.62e-14	-	-	-	-	-	-	-	-
COOLPGFE_01060	1.36e-109	-	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
COOLPGFE_01061	1.36e-74	-	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
COOLPGFE_01062	1.31e-193	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
COOLPGFE_01063	6.56e-94	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
COOLPGFE_01064	7.03e-58	dhaM	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	PTS system fructose IIA component
COOLPGFE_01065	3.02e-162	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
COOLPGFE_01066	4.2e-75	XK27_02085	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
COOLPGFE_01067	2.57e-255	-	-	-	KQ	-	-	-	Hypothetical methyltransferase
COOLPGFE_01068	1.11e-265	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
COOLPGFE_01069	1.68e-198	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
COOLPGFE_01070	7.88e-149	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
COOLPGFE_01071	1.25e-240	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
COOLPGFE_01072	4.84e-102	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
COOLPGFE_01073	8.07e-126	-	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
COOLPGFE_01074	1.16e-184	-	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
COOLPGFE_01077	1.61e-36	-	-	-	-	-	-	-	-
COOLPGFE_01078	1.11e-25	-	-	-	L	-	-	-	transposase and inactivated derivatives, IS30 family
COOLPGFE_01080	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
COOLPGFE_01081	2.76e-42	-	-	-	S	-	-	-	PAS domain
COOLPGFE_01082	2.38e-88	-	-	-	S	-	-	-	PAS domain
COOLPGFE_01084	2.48e-62	-	-	-	GK	-	-	-	ROK family
COOLPGFE_01085	2.33e-43	-	-	-	GK	-	-	-	ROK family
COOLPGFE_01087	1.52e-201	dkgB	-	-	S	-	-	-	reductase
COOLPGFE_01088	1.8e-127	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
COOLPGFE_01089	1.19e-56	-	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	dipeptidase activity
COOLPGFE_01090	5.14e-137	-	-	-	-	-	-	-	-
COOLPGFE_01091	2.94e-106	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
COOLPGFE_01092	2.02e-61	pepI	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
COOLPGFE_01093	1.5e-144	pepI	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
COOLPGFE_01094	4.01e-207	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
COOLPGFE_01095	1.69e-203	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
COOLPGFE_01096	2.11e-34	-	-	-	-	-	-	-	-
COOLPGFE_01097	9.52e-128	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
COOLPGFE_01098	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
COOLPGFE_01099	4.53e-227	-	-	-	-	-	-	-	-
COOLPGFE_01100	1.4e-22	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
COOLPGFE_01101	3.57e-176	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
COOLPGFE_01102	4.3e-22	nt5e	3.1.3.18	-	L	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	haloacid dehalogenase-like hydrolase
COOLPGFE_01103	8.87e-78	-	-	-	S	-	-	-	glycolate biosynthetic process
COOLPGFE_01104	3.75e-206	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
COOLPGFE_01105	7.07e-97	-	-	-	-	-	-	-	-
COOLPGFE_01106	2.11e-221	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
COOLPGFE_01107	2.09e-208	yvgN	-	-	C	-	-	-	Aldo keto reductase
COOLPGFE_01108	0.0	rtpR	1.17.4.2	-	F	ko:K00527	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	ribonucleoside-triphosphate reductase activity
COOLPGFE_01109	1.54e-11	-	-	-	S	-	-	-	Domain of unknown function (DUF4430)
COOLPGFE_01110	5.84e-123	-	-	-	S	ko:K16927	-	ko00000,ko00002,ko02000	ECF transporter, substrate-specific component
COOLPGFE_01111	1.87e-126	-	-	-	S	-	-	-	Cob(I)alamin adenosyltransferase
COOLPGFE_01112	1.15e-191	-	-	-	L	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
COOLPGFE_01113	7.25e-240	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
COOLPGFE_01114	1.36e-178	loxD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
COOLPGFE_01115	1.22e-60	-	-	-	C	-	-	-	FAD linked oxidase domain protein
COOLPGFE_01116	1.23e-96	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
COOLPGFE_01117	2.22e-182	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
COOLPGFE_01118	2.13e-116	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
COOLPGFE_01119	2.72e-237	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
COOLPGFE_01120	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
COOLPGFE_01121	1.29e-114	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
COOLPGFE_01122	3.15e-278	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
COOLPGFE_01123	3.49e-219	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
COOLPGFE_01124	1.1e-181	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
COOLPGFE_01125	4.49e-278	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
COOLPGFE_01126	1.12e-140	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
COOLPGFE_01127	1.46e-39	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
COOLPGFE_01128	1.92e-287	-	-	-	L	-	-	-	Transposase
COOLPGFE_01129	1.24e-145	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
COOLPGFE_01130	3.32e-62	-	-	-	K	ko:K02529	-	ko00000,ko03000	purine nucleotide biosynthetic process
COOLPGFE_01131	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
COOLPGFE_01132	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
COOLPGFE_01133	2.18e-30	-	-	-	L	-	-	-	DDE superfamily endonuclease
COOLPGFE_01135	2.91e-196	-	-	-	S	-	-	-	Protein of unknown function (DUF3298)
COOLPGFE_01136	1.13e-127	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70 region 2
COOLPGFE_01137	0.0	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
COOLPGFE_01138	1.95e-119	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
COOLPGFE_01139	4.92e-136	-	-	-	S	-	-	-	SNARE associated Golgi protein
COOLPGFE_01140	5.49e-195	-	-	-	I	-	-	-	alpha/beta hydrolase fold
COOLPGFE_01141	1.15e-201	plcR	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
COOLPGFE_01142	1.32e-122	-	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside 2-deoxyribosyltransferase
COOLPGFE_01143	3.44e-167	-	-	-	F	-	-	-	glutamine amidotransferase
COOLPGFE_01144	4.36e-300	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
COOLPGFE_01145	2.26e-211	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
COOLPGFE_01146	8.7e-190	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
COOLPGFE_01147	4.66e-178	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
COOLPGFE_01148	1.56e-203	yicL	-	-	EG	-	-	-	EamA-like transporter family
COOLPGFE_01149	5.27e-64	pinR1	-	-	L	-	-	-	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
COOLPGFE_01150	7.26e-39	tnp2	-	-	L	-	-	-	PFAM Transposase, IS204 IS1001 IS1096 IS1165
COOLPGFE_01152	7.68e-265	-	-	-	S	-	-	-	amidohydrolase
COOLPGFE_01153	4.05e-09	XK27_07210	-	-	S	-	-	-	B3 4 domain
COOLPGFE_01154	4.34e-63	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
COOLPGFE_01155	2.31e-213	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
COOLPGFE_01178	2.29e-26	-	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	MafB19-like deaminase
COOLPGFE_01179	1.23e-36	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
COOLPGFE_01180	3.65e-56	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
COOLPGFE_01181	2.13e-106	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
COOLPGFE_01182	3.02e-179	-	-	-	K	-	-	-	LysR family
COOLPGFE_01183	9.72e-47	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
COOLPGFE_01184	3.56e-67	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	COG1053 Succinate dehydrogenase fumarate reductase, flavoprotein subunit
COOLPGFE_01185	4.54e-86	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	COG1053 Succinate dehydrogenase fumarate reductase, flavoprotein subunit
COOLPGFE_01186	1.72e-34	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
COOLPGFE_01187	1.28e-26	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
COOLPGFE_01188	2.28e-217	-	-	-	K	-	-	-	LysR substrate binding domain
COOLPGFE_01189	2.7e-148	-	-	-	K	-	-	-	SIR2-like domain
COOLPGFE_01190	1.1e-68	-	-	-	L	ko:K07484	-	ko00000	IS66 Orf2 like protein
COOLPGFE_01191	2.94e-34	-	-	-	-	-	-	-	-
COOLPGFE_01192	3.01e-264	-	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
COOLPGFE_01193	5.87e-87	-	-	-	L	-	-	-	DDE superfamily endonuclease
COOLPGFE_01194	4.43e-220	-	-	-	S	-	-	-	glycosyl transferase family 2
COOLPGFE_01195	6.97e-84	-	-	-	S	-	-	-	Protein conserved in bacteria
COOLPGFE_01196	8.43e-240	-	-	-	S	ko:K19419	-	ko00000,ko02000	EpsG family
COOLPGFE_01197	6.92e-235	-	-	-	S	-	-	-	Glycosyltransferase like family 2
COOLPGFE_01198	2.51e-84	-	-	-	M	-	-	-	Capsular polysaccharide synthesis protein
COOLPGFE_01199	2e-105	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
COOLPGFE_01200	2.8e-240	-	-	-	G	-	-	-	Glycosyl transferases group 1
COOLPGFE_01201	1.88e-231	-	-	-	M	-	-	-	Glycosyl transferase 4-like
COOLPGFE_01202	2.93e-157	epsE2	-	-	M	-	-	-	Bacterial sugar transferase
COOLPGFE_01203	7.21e-191	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
COOLPGFE_01204	3.89e-149	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
COOLPGFE_01205	3.19e-156	epsB	-	-	M	-	-	-	biosynthesis protein
COOLPGFE_01206	1.39e-233	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
COOLPGFE_01207	6.39e-297	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
COOLPGFE_01208	1.76e-162	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
COOLPGFE_01209	1.81e-159	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
COOLPGFE_01210	1.4e-164	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
COOLPGFE_01211	1.01e-104	lytE	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
COOLPGFE_01212	3.98e-256	idhA	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
COOLPGFE_01213	5.18e-109	lytE	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family
COOLPGFE_01214	9.03e-126	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase homologues.
COOLPGFE_01215	2.89e-64	-	-	-	-	-	-	-	-
COOLPGFE_01216	0.0	-	-	-	S	-	-	-	O-antigen ligase like membrane protein
COOLPGFE_01217	4.02e-145	-	-	-	-	-	-	-	-
COOLPGFE_01218	3.69e-107	-	-	-	-	-	-	-	-
COOLPGFE_01219	8.56e-109	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
COOLPGFE_01220	9.67e-175	-	-	-	S	-	-	-	Putative threonine/serine exporter
COOLPGFE_01221	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
COOLPGFE_01223	2.25e-264	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
COOLPGFE_01224	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
COOLPGFE_01225	4.65e-130	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
COOLPGFE_01226	2.07e-112	-	-	-	KT	-	-	-	response to antibiotic
COOLPGFE_01227	2.09e-173	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
COOLPGFE_01228	1.2e-155	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
COOLPGFE_01229	1.01e-185	-	3.1.3.102, 3.1.3.104, 3.1.3.23	-	G	ko:K07757,ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
COOLPGFE_01230	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
COOLPGFE_01231	1.41e-211	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
COOLPGFE_01232	7.41e-175	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
COOLPGFE_01233	3.86e-186	racD	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
COOLPGFE_01234	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
COOLPGFE_01235	4.19e-283	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
COOLPGFE_01236	3.03e-159	vanR	-	-	K	-	-	-	response regulator
COOLPGFE_01237	2.73e-167	ndvA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
COOLPGFE_01238	7.78e-232	ndvA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
COOLPGFE_01239	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter, ATP-binding protein
COOLPGFE_01240	4.63e-177	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
COOLPGFE_01241	6.88e-257	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
COOLPGFE_01242	6.38e-59	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
COOLPGFE_01243	4.14e-200	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
COOLPGFE_01244	2.37e-176	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
COOLPGFE_01245	2.19e-184	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
COOLPGFE_01246	3.68e-170	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
COOLPGFE_01247	7.44e-113	cvpA	-	-	S	-	-	-	Colicin V production protein
COOLPGFE_01248	4.03e-239	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
COOLPGFE_01249	2.05e-182	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
COOLPGFE_01250	2.48e-124	azr	1.5.1.36	-	S	ko:K22394	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
COOLPGFE_01251	2.92e-126	azo1	1.5.1.36, 1.7.1.6	-	S	ko:K03206,ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
COOLPGFE_01252	4.76e-127	-	-	-	K	-	-	-	WHG domain
COOLPGFE_01253	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
COOLPGFE_01255	3.98e-151	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
COOLPGFE_01256	3.24e-138	-	-	-	-	-	-	-	-
COOLPGFE_01258	2.04e-168	-	-	-	-	-	-	-	-
COOLPGFE_01259	2.79e-153	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
COOLPGFE_01260	4.32e-237	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
COOLPGFE_01261	1.03e-111	-	-	-	K	-	-	-	transcriptional regulator (TetR family)
COOLPGFE_01262	8.05e-106	glcD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
COOLPGFE_01263	5.02e-22	glcD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
COOLPGFE_01264	2.06e-179	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
COOLPGFE_01265	4.7e-150	-	-	-	-	-	-	-	-
COOLPGFE_01266	7.02e-288	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
COOLPGFE_01267	8.79e-63	ydgI	-	-	C	-	-	-	Nitroreductase family
COOLPGFE_01268	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
COOLPGFE_01269	3.44e-45	lysM	-	-	M	-	-	-	LysM domain
COOLPGFE_01270	8.61e-223	citI	-	-	K	-	-	-	Putative sugar-binding domain
COOLPGFE_01271	5.18e-282	-	-	-	M	ko:K08659	-	ko00000,ko01000,ko01002	Peptidase family C69
COOLPGFE_01273	0.0	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
COOLPGFE_01274	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
COOLPGFE_01276	2.01e-195	-	-	-	-	-	-	-	-
COOLPGFE_01277	2.18e-117	ymdB	-	-	S	-	-	-	Macro domain protein
COOLPGFE_01278	4.38e-184	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
COOLPGFE_01279	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
COOLPGFE_01280	3.08e-126	-	-	-	KLT	-	-	-	serine threonine protein kinase
COOLPGFE_01281	0.0	-	-	-	KLT	-	-	-	serine threonine protein kinase
COOLPGFE_01282	1.44e-178	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
COOLPGFE_01283	2.07e-231	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
COOLPGFE_01284	5.78e-53	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
COOLPGFE_01285	3.87e-168	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
COOLPGFE_01286	7.46e-50	-	-	-	-	-	-	-	-
COOLPGFE_01287	0.0	clpL	-	-	O	ko:K04086	-	ko00000,ko03110	C-terminal, D2-small domain, of ClpB protein
COOLPGFE_01288	2.04e-77	-	-	-	T	-	-	-	diguanylate cyclase
COOLPGFE_01289	1.95e-192	-	-	-	L	-	-	-	DDE superfamily endonuclease
COOLPGFE_01290	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
COOLPGFE_01291	4.73e-266	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
COOLPGFE_01292	4.3e-315	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
COOLPGFE_01293	3.29e-233	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
COOLPGFE_01294	2.49e-123	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
COOLPGFE_01295	3.74e-213	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
COOLPGFE_01297	5.44e-277	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
COOLPGFE_01298	0.0	bmr3_1	-	-	EGP	ko:K18935	-	ko00000,ko02000	Sugar (and other) transporter
COOLPGFE_01299	8.07e-155	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
COOLPGFE_01304	3.6e-127	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Aluminium induced protein
COOLPGFE_01305	2.56e-234	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Aluminium induced protein
COOLPGFE_01306	1.3e-205	-	-	-	J	-	-	-	Methyltransferase
COOLPGFE_01307	3.15e-14	-	-	-	G	-	-	-	polysaccharide deacetylase
COOLPGFE_01308	3.82e-183	-	-	-	G	-	-	-	polysaccharide deacetylase
COOLPGFE_01309	5.53e-265	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
COOLPGFE_01310	7.41e-06	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
COOLPGFE_01311	5.43e-97	-	-	-	-	-	-	-	-
COOLPGFE_01327	1.46e-236	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
COOLPGFE_01328	5.45e-153	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
COOLPGFE_01329	4.03e-137	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
COOLPGFE_01330	5.46e-185	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
COOLPGFE_01331	5.27e-112	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
COOLPGFE_01332	0.0	sasH	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01081,ko:K01119,ko:K07004,ko:K08693,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
COOLPGFE_01333	2.89e-77	-	-	-	-	-	-	-	-
COOLPGFE_01334	2.14e-232	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
COOLPGFE_01335	6.81e-274	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
COOLPGFE_01337	5.67e-34	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
COOLPGFE_01338	4.86e-59	-	-	-	-	-	-	-	-
COOLPGFE_01339	1.15e-24	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
COOLPGFE_01340	5.67e-196	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
COOLPGFE_01341	1.78e-147	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
COOLPGFE_01342	1.01e-87	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
COOLPGFE_01343	3.11e-71	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
COOLPGFE_01344	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
COOLPGFE_01345	1.92e-67	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
COOLPGFE_01346	6.34e-94	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
COOLPGFE_01347	5.13e-55	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
COOLPGFE_01348	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
COOLPGFE_01349	1.74e-294	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
COOLPGFE_01350	1.89e-228	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
COOLPGFE_01351	4.03e-263	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
COOLPGFE_01352	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
COOLPGFE_01353	1.21e-70	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
COOLPGFE_01354	1.02e-236	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
COOLPGFE_01355	4.05e-135	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
COOLPGFE_01356	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
COOLPGFE_01357	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
COOLPGFE_01358	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
COOLPGFE_01359	3.69e-59	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
COOLPGFE_01360	2.3e-158	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
COOLPGFE_01361	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
COOLPGFE_01362	1.43e-248	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
COOLPGFE_01363	9.08e-124	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
COOLPGFE_01364	5.82e-163	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
COOLPGFE_01365	1.56e-115	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
COOLPGFE_01366	5.22e-114	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
COOLPGFE_01367	6.15e-183	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
COOLPGFE_01368	9.14e-204	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
COOLPGFE_01369	2.21e-72	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
COOLPGFE_01370	5.96e-206	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
COOLPGFE_01371	1.83e-70	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
COOLPGFE_01372	2.32e-146	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
COOLPGFE_01373	2.21e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
COOLPGFE_01374	3.6e-139	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
COOLPGFE_01375	1.9e-68	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
COOLPGFE_01376	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
COOLPGFE_01377	2.25e-116	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
COOLPGFE_01378	1.79e-144	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
COOLPGFE_01379	2.31e-117	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
COOLPGFE_01380	1.47e-96	-	-	-	-	-	-	-	-
COOLPGFE_01381	8.5e-74	-	-	-	-	-	-	-	-
COOLPGFE_01382	7.83e-60	-	-	-	-	-	-	-	-
COOLPGFE_01383	2.25e-16	-	-	-	L	ko:K07483,ko:K07497	-	ko00000	Helix-turn-helix domain
COOLPGFE_01384	7.54e-264	pbpX1	-	-	V	-	-	-	Beta-lactamase
COOLPGFE_01385	6.48e-174	pbpX	-	-	V	-	-	-	Beta-lactamase
COOLPGFE_01386	1.49e-54	-	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
COOLPGFE_01387	1.84e-27	-	5.3.1.6	-	G	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose/Galactose Isomerase
COOLPGFE_01388	1.22e-15	rpiB2	5.3.1.6	-	G	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose/Galactose Isomerase
COOLPGFE_01390	1.7e-76	-	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
COOLPGFE_01391	9.22e-18	-	-	-	P	-	-	-	nitric oxide dioxygenase activity
COOLPGFE_01392	4.29e-185	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
COOLPGFE_01393	7.87e-111	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
COOLPGFE_01394	1.42e-71	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
COOLPGFE_01395	1.35e-108	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
COOLPGFE_01396	2.23e-20	-	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
COOLPGFE_01397	2.1e-93	-	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
COOLPGFE_01398	3.39e-94	-	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
COOLPGFE_01399	5.15e-91	-	-	-	-	-	-	-	-
COOLPGFE_01400	3.81e-293	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
COOLPGFE_01401	2.09e-244	-	-	-	S	-	-	-	Glycosyl transferase family 2
COOLPGFE_01402	4.45e-158	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
COOLPGFE_01403	3.27e-91	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
COOLPGFE_01404	5.63e-131	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
COOLPGFE_01405	3.07e-32	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
COOLPGFE_01406	7.32e-28	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
COOLPGFE_01407	2.07e-38	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
COOLPGFE_01408	8.44e-124	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
COOLPGFE_01409	8.92e-60	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
COOLPGFE_01410	2.32e-150	-	-	-	S	-	-	-	Alpha/beta hydrolase family
COOLPGFE_01411	3.19e-45	-	-	-	-	-	-	-	-
COOLPGFE_01412	5.81e-131	-	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factor activity
COOLPGFE_01413	1.34e-177	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
COOLPGFE_01414	6.26e-101	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
COOLPGFE_01415	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
COOLPGFE_01416	6.07e-137	-	-	-	F	-	-	-	NUDIX domain
COOLPGFE_01417	3.88e-207	-	-	-	K	-	-	-	LysR substrate binding domain
COOLPGFE_01418	9.35e-231	-	-	-	S	-	-	-	Conserved hypothetical protein 698
COOLPGFE_01419	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
COOLPGFE_01421	2.19e-154	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
COOLPGFE_01422	7.32e-79	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
COOLPGFE_01424	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
COOLPGFE_01425	1.06e-121	-	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
COOLPGFE_01426	1.98e-103	-	-	-	F	-	-	-	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
COOLPGFE_01427	4.75e-180	-	-	-	F	-	-	-	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
COOLPGFE_01428	5.61e-34	-	6.3.4.18, 6.3.5.5	-	F	ko:K01589,ko:K01955,ko:K16181	ko00230,ko00240,ko00250,ko00300,ko01100,ko01110,ko01120,ko01130,map00230,map00240,map00250,map00300,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	5-(carboxyamino)imidazole ribonucleotide synthase activity
COOLPGFE_01429	8.81e-05	-	6.3.4.18, 6.3.5.5	-	F	ko:K01589,ko:K01955,ko:K16181	ko00230,ko00240,ko00250,ko00300,ko01100,ko01110,ko01120,ko01130,map00230,map00240,map00250,map00300,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	5-(carboxyamino)imidazole ribonucleotide synthase activity
COOLPGFE_01430	6.7e-205	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
COOLPGFE_01431	6.14e-259	-	-	-	-	-	-	-	-
COOLPGFE_01432	8.28e-273	-	-	-	EGP	-	-	-	Transmembrane secretion effector
COOLPGFE_01433	4.78e-272	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
COOLPGFE_01434	1.71e-95	-	-	-	T	-	-	-	diguanylate cyclase
COOLPGFE_01435	1.29e-23	-	-	-	T	-	-	-	diguanylate cyclase
COOLPGFE_01437	1.77e-142	-	-	-	T	-	-	-	EAL domain
COOLPGFE_01438	9.89e-15	-	-	-	T	-	-	-	diguanylate cyclase
COOLPGFE_01439	7.27e-112	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
COOLPGFE_01440	0.0	-	1.1.1.1, 1.2.1.10, 1.2.1.87	-	C	ko:K04072,ko:K13922	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Aldehyde dehydrogenase family
COOLPGFE_01441	2.03e-185	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
COOLPGFE_01442	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
COOLPGFE_01443	7.66e-130	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
COOLPGFE_01444	2.84e-205	XK27_10120	-	-	K	-	-	-	S-adenosyl-l-methionine hydroxide adenosyltransferase
COOLPGFE_01445	0.0	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
COOLPGFE_01446	0.0	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-type transport system involved in multi-copper enzyme maturation permease component
COOLPGFE_01447	1.27e-217	potA5	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
COOLPGFE_01448	2.53e-80	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
COOLPGFE_01454	3.25e-35	-	-	-	L	-	-	-	Transposase
COOLPGFE_01456	3.62e-38	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
COOLPGFE_01457	3.87e-74	qorB	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NmrA-like family
COOLPGFE_01458	6.01e-45	qorB	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	epimerase
COOLPGFE_01459	1.89e-95	ywnA	-	-	K	-	-	-	Transcriptional regulator
COOLPGFE_01460	1.33e-110	-	-	-	S	-	-	-	YcxB-like protein
COOLPGFE_01461	1.07e-129	-	-	-	T	-	-	-	integral membrane protein
COOLPGFE_01462	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
COOLPGFE_01463	2.64e-116	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
COOLPGFE_01464	3.56e-196	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
COOLPGFE_01465	1.01e-33	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
COOLPGFE_01466	2.85e-15	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
COOLPGFE_01467	0.0	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
COOLPGFE_01469	5.36e-171	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
COOLPGFE_01470	1.1e-144	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
COOLPGFE_01472	6.96e-30	-	-	-	-	-	-	-	-
COOLPGFE_01473	0.0	-	-	-	KLT	-	-	-	Protein kinase domain
COOLPGFE_01474	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K06147,ko:K11085,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
COOLPGFE_01475	3.6e-35	-	-	-	-	-	-	-	-
COOLPGFE_01477	6.68e-244	pltK	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
COOLPGFE_01478	2.67e-178	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
COOLPGFE_01479	5.39e-77	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
COOLPGFE_01480	3.11e-152	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
COOLPGFE_01481	2.35e-213	-	-	-	V	-	-	-	ABC transporter transmembrane region
COOLPGFE_01482	3.4e-95	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
COOLPGFE_01484	3.24e-157	-	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
COOLPGFE_01486	4.46e-90	-	-	-	-	-	-	-	-
COOLPGFE_01487	0.0	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
COOLPGFE_01488	4.21e-288	-	-	-	S	-	-	-	Protein of unknown function (DUF2974)
COOLPGFE_01489	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
COOLPGFE_01490	1.11e-96	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
COOLPGFE_01491	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
COOLPGFE_01492	1.61e-48	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
COOLPGFE_01493	1.79e-126	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
COOLPGFE_01494	1e-62	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
COOLPGFE_01495	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
COOLPGFE_01496	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
COOLPGFE_01497	2.02e-268	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
COOLPGFE_01498	2.22e-50	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
COOLPGFE_01499	9.76e-257	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
COOLPGFE_01500	1.7e-313	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
COOLPGFE_01501	6.59e-23	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
COOLPGFE_01502	1.48e-82	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
COOLPGFE_01503	1.28e-195	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
COOLPGFE_01504	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
COOLPGFE_01505	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
COOLPGFE_01506	0.0	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
COOLPGFE_01507	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
COOLPGFE_01508	1.35e-97	-	-	-	-	-	-	-	-
COOLPGFE_01509	3.4e-86	-	-	-	-	-	-	-	-
COOLPGFE_01510	6.76e-180	-	-	-	-	-	-	-	-
COOLPGFE_01511	1.26e-122	-	-	-	-	-	-	-	-
COOLPGFE_01512	2.81e-141	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
COOLPGFE_01513	5.48e-135	-	-	-	-	-	-	-	-
COOLPGFE_01514	1.05e-147	-	-	-	-	-	-	-	-
COOLPGFE_01515	3.79e-119	-	-	-	-	-	-	-	-
COOLPGFE_01516	1.51e-91	-	-	-	-	-	-	-	-
COOLPGFE_01517	2.56e-20	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
COOLPGFE_01518	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
COOLPGFE_01519	1.55e-293	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
COOLPGFE_01520	8.7e-178	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
COOLPGFE_01521	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
COOLPGFE_01522	1.14e-165	dgk2	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
COOLPGFE_01523	6.66e-159	dak	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
COOLPGFE_01524	4.44e-51	-	-	-	-	-	-	-	-
COOLPGFE_01525	4.95e-196	ybfG	-	-	M	-	-	-	peptidoglycan-binding domain-containing protein
COOLPGFE_01527	3.02e-19	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
COOLPGFE_01529	1.66e-49	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
COOLPGFE_01530	1.78e-202	-	-	-	S	-	-	-	Aldo/keto reductase family
COOLPGFE_01531	2.9e-120	-	-	-	EGP	-	-	-	Major Facilitator
COOLPGFE_01532	1.03e-77	-	-	-	EGP	-	-	-	Major Facilitator
COOLPGFE_01533	1.36e-09	-	-	-	EGP	-	-	-	Major Facilitator
COOLPGFE_01534	1.04e-220	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
COOLPGFE_01535	3.73e-263	mglC	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
COOLPGFE_01536	0.0	mglA	3.6.3.17	-	S	ko:K02056,ko:K06400	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
COOLPGFE_01537	1.82e-254	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein PnrA-like
COOLPGFE_01538	5.6e-251	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein PnrA-like
COOLPGFE_01539	3.65e-95	-	-	-	S	-	-	-	Domain of unknown function (DUF4352)
COOLPGFE_01540	2.43e-240	pkn2	-	-	KLT	-	-	-	Protein tyrosine kinase
COOLPGFE_01541	1.35e-85	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
COOLPGFE_01543	2.36e-249	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein PnrA-like
COOLPGFE_01544	8.03e-256	-	-	-	S	-	-	-	DUF218 domain
COOLPGFE_01545	7.53e-158	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
COOLPGFE_01546	2.79e-257	napA	-	-	P	-	-	-	Sodium/hydrogen exchanger family
COOLPGFE_01547	0.0	cadA	-	-	P	-	-	-	P-type ATPase
COOLPGFE_01548	1.04e-110	ykuL	-	-	S	-	-	-	(CBS) domain
COOLPGFE_01549	2.61e-82	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
COOLPGFE_01550	1.86e-286	-	-	-	S	-	-	-	Membrane
COOLPGFE_01551	1.75e-38	-	-	-	-	-	-	-	-
COOLPGFE_01552	0.000111	-	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
COOLPGFE_01553	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
COOLPGFE_01554	4.55e-307	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
COOLPGFE_01555	1.12e-49	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
COOLPGFE_01556	5.44e-315	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
COOLPGFE_01558	4.13e-86	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
COOLPGFE_01559	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
COOLPGFE_01560	3.58e-148	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
COOLPGFE_01567	1.69e-65	-	-	-	S	-	-	-	Domain of Unknown Function with PDB structure (DUF3862)
COOLPGFE_01569	8.75e-160	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
COOLPGFE_01570	5.2e-163	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
COOLPGFE_01571	2.12e-177	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
COOLPGFE_01572	1.85e-205	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
COOLPGFE_01573	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
COOLPGFE_01574	6.26e-101	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
COOLPGFE_01575	1.21e-93	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
COOLPGFE_01576	3.77e-288	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
COOLPGFE_01577	1.53e-158	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
COOLPGFE_01578	5.44e-230	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
COOLPGFE_01579	1.31e-44	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
COOLPGFE_01580	2.37e-222	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
COOLPGFE_01581	1.75e-234	ydbI	-	-	K	-	-	-	AI-2E family transporter
COOLPGFE_01582	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
COOLPGFE_01583	6.11e-13	-	-	-	-	-	-	-	-
COOLPGFE_01584	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
COOLPGFE_01585	5e-311	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
COOLPGFE_01586	2.42e-97	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
COOLPGFE_01587	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
COOLPGFE_01588	2.28e-222	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
COOLPGFE_01589	1.16e-115	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
COOLPGFE_01590	3.13e-308	-	-	-	S	-	-	-	Putative threonine/serine exporter
COOLPGFE_01591	6.16e-282	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
COOLPGFE_01592	9.4e-275	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
COOLPGFE_01593	4.76e-248	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
COOLPGFE_01594	2.29e-291	sptS	-	-	T	-	-	-	Histidine kinase
COOLPGFE_01595	1.55e-149	dltr	-	-	K	-	-	-	response regulator
COOLPGFE_01596	8.48e-145	-	-	-	T	-	-	-	Region found in RelA / SpoT proteins
COOLPGFE_01597	1.83e-200	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR-associated protein (Cas_Cas2CT1978)
COOLPGFE_01598	2.28e-223	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
COOLPGFE_01599	1.71e-150	casE	-	-	S	ko:K19126	-	ko00000,ko02048	CRISPR_assoc
COOLPGFE_01600	1.1e-168	casD	-	-	S	ko:K19125	-	ko00000,ko02048	CRISPR-associated protein (Cas_Cas5)
COOLPGFE_01601	6.88e-237	casC	-	-	L	ko:K19124	-	ko00000,ko02048	CT1975-like protein
COOLPGFE_01602	1.41e-142	-	-	-	S	ko:K19046	-	ko00000,ko02048	CRISPR-associated protein Cse2 (CRISPR_cse2)
COOLPGFE_01603	0.0	casA	-	-	L	ko:K19123	-	ko00000,ko02048	the current gene model (or a revised gene model) may contain a frame shift
COOLPGFE_01604	0.0	cas3	-	-	L	ko:K07012	-	ko00000,ko01000,ko02048	CRISPR-associated helicase cas3
COOLPGFE_01606	8.89e-26	-	-	-	-	-	-	-	-
COOLPGFE_01608	1.02e-98	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
COOLPGFE_01609	9.54e-118	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
COOLPGFE_01611	5.36e-93	-	-	-	-	-	-	-	-
COOLPGFE_01612	0.0	-	-	-	I	-	-	-	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
COOLPGFE_01614	2.61e-35	-	-	-	-	-	-	-	-
COOLPGFE_01615	4.57e-134	-	-	-	K	ko:K13928	-	ko00000,ko03000	DNA-binding transcription factor activity
COOLPGFE_01616	1.77e-11	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
COOLPGFE_01617	4.53e-143	-	-	-	K	-	-	-	LysR substrate binding domain
COOLPGFE_01618	7.38e-44	-	-	-	K	-	-	-	LysR substrate binding domain
COOLPGFE_01619	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
COOLPGFE_01620	1.68e-292	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
COOLPGFE_01621	5.57e-55	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
COOLPGFE_01622	7.74e-314	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
COOLPGFE_01623	2.15e-280	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
COOLPGFE_01624	1.22e-139	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
COOLPGFE_01625	5.23e-06	mltD	-	-	M	ko:K08307	-	ko00000,ko01000,ko01011	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
COOLPGFE_01626	3.33e-150	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
COOLPGFE_01627	4.13e-167	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
COOLPGFE_01628	1.77e-135	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
COOLPGFE_01629	6.52e-164	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
COOLPGFE_01630	2.22e-82	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
COOLPGFE_01631	1.26e-211	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
COOLPGFE_01632	4.38e-209	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
COOLPGFE_01633	1.89e-119	-	-	-	I	-	-	-	Acyltransferase family
COOLPGFE_01634	5.98e-72	ssuB	-	-	P	ko:K02049,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	anion transmembrane transporter activity
COOLPGFE_01635	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
COOLPGFE_01636	1.62e-229	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
COOLPGFE_01637	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
COOLPGFE_01638	2.87e-39	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
COOLPGFE_01639	1.68e-116	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
COOLPGFE_01640	6.57e-72	-	-	-	K	ko:K03492	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
COOLPGFE_01641	2.82e-19	-	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA
COOLPGFE_01642	1.37e-128	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
COOLPGFE_01644	5.63e-45	-	-	-	-	-	-	-	-
COOLPGFE_01645	0.0	-	-	-	L	-	-	-	SNF2 family N-terminal domain
COOLPGFE_01646	0.0	yfkN	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
COOLPGFE_01647	3.88e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
COOLPGFE_01648	3.49e-176	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
COOLPGFE_01649	1.09e-222	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
COOLPGFE_01650	0.0	oatA	-	-	I	-	-	-	Acyltransferase
COOLPGFE_01651	6.47e-298	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
COOLPGFE_01652	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
COOLPGFE_01653	1.45e-233	iunH	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	inosine-uridine preferring nucleoside hydrolase
COOLPGFE_01654	9.49e-76	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
COOLPGFE_01655	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
COOLPGFE_01656	6.55e-223	gyaR	1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81	-	CH	ko:K00015,ko:K00090	ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
COOLPGFE_01657	1.76e-259	-	-	-	S	ko:K07045	-	ko00000	Amidohydrolase
COOLPGFE_01658	2.34e-283	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
COOLPGFE_01659	6.58e-101	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
COOLPGFE_01660	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
COOLPGFE_01661	4.21e-213	yvbU	-	-	K	-	-	-	LysR substrate binding domain
COOLPGFE_01662	5.95e-302	-	-	-	EK	-	-	-	Aminotransferase, class I
COOLPGFE_01663	1.67e-91	-	-	-	E	-	-	-	Methionine synthase
COOLPGFE_01667	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
COOLPGFE_01668	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
COOLPGFE_01669	2.03e-73	ppsA	2.7.9.2	-	G	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the PEP-utilizing enzyme family
COOLPGFE_01670	1.45e-70	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
COOLPGFE_01671	2e-202	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
COOLPGFE_01672	9.45e-67	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
COOLPGFE_01673	4.88e-88	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
COOLPGFE_01674	2.65e-228	-	-	-	-	-	-	-	-
COOLPGFE_01675	1.38e-183	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
COOLPGFE_01676	9.36e-173	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
COOLPGFE_01678	7.15e-295	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
COOLPGFE_01679	4.69e-202	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
COOLPGFE_01680	0.0	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
COOLPGFE_01682	2.63e-99	-	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
COOLPGFE_01683	3.25e-79	-	-	-	-	-	-	-	-
COOLPGFE_01684	6.37e-76	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
COOLPGFE_01685	2.17e-122	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
COOLPGFE_01686	9.99e-216	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
COOLPGFE_01687	7.86e-207	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
COOLPGFE_01688	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
COOLPGFE_01689	3.16e-73	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
COOLPGFE_01690	8.89e-289	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
COOLPGFE_01691	0.0	yhaN	-	-	L	-	-	-	AAA domain
COOLPGFE_01692	1.28e-229	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
COOLPGFE_01693	1.81e-86	aroK	1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4	-	F	ko:K00014,ko:K00891,ko:K03785,ko:K03786,ko:K13829,ko:K15546	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko03000	shikimate kinase activity
COOLPGFE_01694	5.07e-64	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
COOLPGFE_01695	8.28e-199	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
COOLPGFE_01696	9.14e-146	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
COOLPGFE_01697	2.5e-173	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
COOLPGFE_01698	1.17e-217	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
COOLPGFE_01699	1.4e-71	-	-	-	-	-	-	-	-
COOLPGFE_01700	5.82e-105	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
COOLPGFE_01701	3.02e-176	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
COOLPGFE_01702	1.28e-274	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
COOLPGFE_01703	1.64e-158	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
COOLPGFE_01704	9.52e-72	ytpP	-	-	CO	-	-	-	Thioredoxin
COOLPGFE_01705	6.93e-154	XK27_10290	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
COOLPGFE_01706	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
COOLPGFE_01707	1.67e-27	-	-	-	K	-	-	-	Transcriptional regulator
COOLPGFE_01708	2.8e-19	-	-	-	EGP	-	-	-	Major facilitator Superfamily
COOLPGFE_01709	7.87e-71	-	-	-	EGP	-	-	-	Major Facilitator
COOLPGFE_01710	9.6e-50	-	-	-	P	-	-	-	nitrite transmembrane transporter activity
COOLPGFE_01711	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
COOLPGFE_01712	1.03e-202	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
COOLPGFE_01713	1.03e-131	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
COOLPGFE_01714	1.57e-107	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
COOLPGFE_01715	5.47e-314	dnaB2	-	-	L	ko:K03346	-	ko00000,ko03032	Replication initiation and membrane attachment
COOLPGFE_01716	4.07e-217	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
COOLPGFE_01717	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
COOLPGFE_01718	0.0	-	-	-	S	ko:K06921	-	ko00000	Archaea bacterial proteins of unknown function
COOLPGFE_01719	2.29e-145	-	-	-	L	-	-	-	Resolvase, N terminal domain
COOLPGFE_01720	0.0	-	-	-	L	-	-	-	Putative transposase DNA-binding domain
COOLPGFE_01721	3.99e-112	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
COOLPGFE_01722	1.37e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
COOLPGFE_01723	2.91e-74	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
COOLPGFE_01724	1.16e-270	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
COOLPGFE_01725	1.58e-153	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
COOLPGFE_01726	6.76e-143	yqeK	-	-	H	-	-	-	Hydrolase, HD family
COOLPGFE_01727	1.46e-77	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
COOLPGFE_01728	1.68e-273	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
COOLPGFE_01729	2.09e-130	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
COOLPGFE_01730	1.96e-164	csrR	-	-	K	-	-	-	response regulator
COOLPGFE_01731	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
COOLPGFE_01732	4.75e-202	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
COOLPGFE_01733	5.39e-61	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
COOLPGFE_01734	1.27e-173	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
COOLPGFE_01735	9.83e-81	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
COOLPGFE_01736	4.12e-254	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
COOLPGFE_01737	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
COOLPGFE_01738	2.55e-105	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
COOLPGFE_01739	0.0	-	-	-	S	-	-	-	membrane
COOLPGFE_01740	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
COOLPGFE_01741	2.18e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
COOLPGFE_01742	2.26e-132	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
COOLPGFE_01743	6.09e-152	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Rhomboid family
COOLPGFE_01744	2.98e-45	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
COOLPGFE_01745	8.9e-92	yqhL	-	-	P	-	-	-	Rhodanese-like protein
COOLPGFE_01746	1.87e-218	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
COOLPGFE_01747	1.04e-206	ynbB	-	-	P	-	-	-	aluminum resistance
COOLPGFE_01748	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
COOLPGFE_01749	7.46e-279	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
COOLPGFE_01750	1.47e-83	-	-	-	S	-	-	-	Domain of unknown function DUF1828
COOLPGFE_01751	5.59e-75	-	-	-	-	-	-	-	-
COOLPGFE_01752	1.92e-238	add	3.5.4.2, 3.5.4.4	-	F	ko:K01488,ko:K02029,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
COOLPGFE_01753	1.55e-260	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
COOLPGFE_01754	4.43e-294	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
COOLPGFE_01755	3.14e-31	-	-	-	L	-	-	-	Transposase
COOLPGFE_01756	4.74e-71	-	-	-	L	-	-	-	DDE superfamily endonuclease
COOLPGFE_01757	8.22e-217	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
COOLPGFE_01758	9.68e-106	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
COOLPGFE_01760	1.68e-70	-	-	-	S	-	-	-	Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units
COOLPGFE_01761	0.0	XK27_08315	-	-	M	-	-	-	Sulfatase
COOLPGFE_01762	4.15e-93	plsY1	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
COOLPGFE_01763	2.71e-24	plsY1	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
COOLPGFE_01764	9.16e-272	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
COOLPGFE_01765	2.71e-167	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
COOLPGFE_01766	7.96e-170	-	-	-	-	-	-	-	-
COOLPGFE_01767	2.6e-93	-	-	-	S	-	-	-	Oxidoreductase
COOLPGFE_01768	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
COOLPGFE_01769	0.0	-	3.2.1.96, 3.5.1.28	GH73	M	ko:K01227,ko:K01447,ko:K13714,ko:K13731	ko00511,ko05100,map00511,map05100	ko00000,ko00001,ko01000	N-acetylmuramoyl-L-alanine amidase
COOLPGFE_01770	1.24e-228	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
COOLPGFE_01771	6.35e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
COOLPGFE_01772	1.23e-39	-	-	-	-	-	-	-	-
COOLPGFE_01773	2.96e-175	-	-	-	-	-	-	-	-
COOLPGFE_01774	2.42e-96	-	-	-	-	-	-	-	-
COOLPGFE_01775	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
COOLPGFE_01776	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
COOLPGFE_01777	2.18e-82	-	-	-	O	-	-	-	Glutaredoxin-related protein
COOLPGFE_01778	3.77e-288	yqjV	-	-	EGP	-	-	-	Major Facilitator Superfamily
COOLPGFE_01779	5.06e-62	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
COOLPGFE_01780	1.22e-113	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
COOLPGFE_01781	2.47e-27	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
COOLPGFE_01782	2.49e-27	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
COOLPGFE_01783	7.21e-182	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
COOLPGFE_01784	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
COOLPGFE_01785	5.46e-315	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
COOLPGFE_01786	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
COOLPGFE_01787	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
COOLPGFE_01788	3e-108	-	-	-	-	-	-	-	-
COOLPGFE_01789	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
COOLPGFE_01790	5.24e-190	-	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
COOLPGFE_01791	2.63e-172	phnB	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
COOLPGFE_01792	2.39e-179	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
COOLPGFE_01793	4.89e-212	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
COOLPGFE_01794	3.83e-109	usp5	-	-	T	-	-	-	universal stress protein
COOLPGFE_01795	1.61e-185	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
COOLPGFE_01796	3.14e-109	-	2.7.1.200, 2.7.1.204	-	G	ko:K02773,ko:K20112	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
COOLPGFE_01797	2.59e-116	ntd	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside
COOLPGFE_01798	6.17e-284	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
COOLPGFE_01799	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
COOLPGFE_01800	2.65e-186	malG	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
COOLPGFE_01801	2.03e-127	malF	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
COOLPGFE_01802	1.46e-109	dexB	3.2.1.70	-	G	ko:K01215	-	ko00000,ko01000	Alpha amylase, catalytic domain protein
COOLPGFE_01803	4.6e-218	-	-	-	I	-	-	-	alpha/beta hydrolase fold
COOLPGFE_01804	1.98e-166	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
COOLPGFE_01805	6.42e-243	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
COOLPGFE_01807	4.03e-263	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
COOLPGFE_01808	3.59e-263	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
COOLPGFE_01809	2.41e-150	crp2	-	-	K	ko:K10914,ko:K21562	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
COOLPGFE_01810	1.67e-185	-	-	-	-	-	-	-	-
COOLPGFE_01811	1.83e-159	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
COOLPGFE_01812	1.03e-237	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
COOLPGFE_01813	1.92e-162	-	-	-	S	-	-	-	Alpha/beta hydrolase family
COOLPGFE_01814	2.85e-205	epsV	-	-	S	-	-	-	glycosyl transferase family 2
COOLPGFE_01815	8.04e-209	-	-	-	S	-	-	-	Protein of unknown function (DUF1002)
COOLPGFE_01816	1.37e-173	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
COOLPGFE_01817	1.9e-230	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
COOLPGFE_01818	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
COOLPGFE_01819	1.43e-105	-	-	-	-	-	-	-	-
COOLPGFE_01820	2.93e-168	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
COOLPGFE_01821	9.2e-87	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
COOLPGFE_01822	6.22e-158	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
COOLPGFE_01823	0.0	XK27_05795	-	-	P	ko:K17073,ko:K17074	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
COOLPGFE_01824	2.81e-181	glnQ	-	-	E	ko:K17076	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
COOLPGFE_01826	1.32e-152	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
COOLPGFE_01827	1.13e-221	-	-	-	L	-	-	-	HNH nucleases
COOLPGFE_01828	5.79e-23	-	-	-	-	-	-	-	-
COOLPGFE_01829	5.3e-264	ysdE	-	-	P	-	-	-	Citrate transporter
COOLPGFE_01830	1.67e-123	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
COOLPGFE_01831	9.42e-203	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
COOLPGFE_01832	3.42e-195	mutR	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
COOLPGFE_01833	4.84e-284	-	-	-	S	ko:K09136	-	ko00000,ko03009	ATP diphosphatase activity
COOLPGFE_01835	3.96e-177	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
COOLPGFE_01836	2.22e-155	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
COOLPGFE_01837	1.21e-217	-	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
COOLPGFE_01838	6.12e-195	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
COOLPGFE_01839	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
COOLPGFE_01840	0.0	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
COOLPGFE_01841	7.38e-148	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
COOLPGFE_01842	4.51e-25	-	-	-	L	-	-	-	transposase and inactivated derivatives, IS30 family
COOLPGFE_01843	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
COOLPGFE_01844	8.99e-104	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
COOLPGFE_01845	1.77e-118	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
COOLPGFE_01846	4.69e-10	-	-	-	Q	-	-	-	phosphatase activity
COOLPGFE_01847	1.45e-239	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase, type I
COOLPGFE_01848	4.05e-98	-	-	-	K	-	-	-	DNA-binding transcription factor activity
COOLPGFE_01849	5.71e-08	tyrA	1.3.1.12, 5.4.99.5	-	E	ko:K14187	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	chorismate mutase
COOLPGFE_01850	7.43e-68	-	-	-	S	-	-	-	Aminoacyl-tRNA editing domain
COOLPGFE_01851	1.75e-11	-	-	-	S	-	-	-	Aminoacyl-tRNA editing domain
COOLPGFE_01852	5.83e-223	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
COOLPGFE_01853	2.44e-141	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
COOLPGFE_01854	3.57e-60	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
COOLPGFE_01855	1.41e-215	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
COOLPGFE_01856	0.0	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
COOLPGFE_01857	7.71e-165	-	-	-	F	-	-	-	Phosphorylase superfamily
COOLPGFE_01859	3.63e-165	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
COOLPGFE_01860	6.82e-171	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
COOLPGFE_01861	4.74e-177	fliY	-	-	ET	ko:K02030,ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
COOLPGFE_01864	5.1e-303	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
COOLPGFE_01865	5.11e-180	-	-	-	K	-	-	-	Transcriptional regulator
COOLPGFE_01866	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
COOLPGFE_01867	0.0	-	-	-	KLT	-	-	-	Protein kinase domain
COOLPGFE_01868	7.29e-84	-	-	-	S	-	-	-	HicB family
COOLPGFE_01869	5.02e-52	-	-	-	S	-	-	-	HicA toxin of bacterial toxin-antitoxin,
COOLPGFE_01870	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
COOLPGFE_01871	2.95e-263	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
COOLPGFE_01872	2.76e-129	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
COOLPGFE_01873	3.79e-291	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
COOLPGFE_01874	6.71e-85	-	-	-	-	-	-	-	-
COOLPGFE_01875	0.0	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
COOLPGFE_01876	4.21e-242	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
COOLPGFE_01877	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
COOLPGFE_01878	2.07e-102	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
COOLPGFE_01879	6.11e-96	-	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
COOLPGFE_01880	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Papain family cysteine protease
COOLPGFE_01881	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
COOLPGFE_01882	1.09e-226	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
COOLPGFE_01883	2.78e-251	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
COOLPGFE_01884	3.19e-239	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
COOLPGFE_01885	1.09e-200	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
COOLPGFE_01886	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
COOLPGFE_01887	1.03e-36	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
COOLPGFE_01888	4.42e-63	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
COOLPGFE_01889	4.15e-160	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
COOLPGFE_01890	5.19e-42	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	transmembrane transport
COOLPGFE_01891	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
COOLPGFE_01892	4.26e-220	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
COOLPGFE_01893	3.11e-78	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
COOLPGFE_01894	9.42e-30	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
COOLPGFE_01895	9.11e-155	ypgQ	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
COOLPGFE_01896	1.27e-311	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
COOLPGFE_01897	2.47e-164	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
COOLPGFE_01898	2.29e-297	amd	-	-	E	-	-	-	Peptidase family M20/M25/M40
COOLPGFE_01899	3.06e-123	steT	-	-	E	ko:K03294	-	ko00000	amino acid
COOLPGFE_01900	4.09e-80	-	-	-	S	ko:K07006	-	ko00000	Pyridoxamine 5'-phosphate oxidase
COOLPGFE_01902	3.23e-308	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
COOLPGFE_01904	2.53e-205	cjaA	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
COOLPGFE_01905	4.14e-175	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
COOLPGFE_01906	1.39e-121	glnP7	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter permease
COOLPGFE_01907	1.32e-144	glnP9	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter, permease protein
COOLPGFE_01908	4.67e-127	-	3.6.1.67	-	F	ko:K19965	ko00790,map00790	ko00000,ko00001,ko00002,ko01000	NUDIX domain
COOLPGFE_01909	7.12e-256	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydropteroate synthase
COOLPGFE_01910	0.0	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
COOLPGFE_01911	1.06e-260	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
COOLPGFE_01912	8.76e-75	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
COOLPGFE_01913	3.45e-25	nth2	-	-	L	ko:K07457	-	ko00000	Base excision DNA repair protein, HhH-GPD family
COOLPGFE_01914	5.42e-32	-	-	-	L	-	-	-	Transposase