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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HFLCNNMA_00001	3.43e-43	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HFLCNNMA_00002	1.11e-25	-	-	-	L	-	-	-	transposase and inactivated derivatives, IS30 family
HFLCNNMA_00003	7.38e-148	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HFLCNNMA_00004	0.0	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HFLCNNMA_00005	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
HFLCNNMA_00006	6.12e-195	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HFLCNNMA_00007	1.21e-217	-	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HFLCNNMA_00008	2.22e-155	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HFLCNNMA_00009	3.96e-177	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HFLCNNMA_00011	4.84e-284	-	-	-	S	ko:K09136	-	ko00000,ko03009	ATP diphosphatase activity
HFLCNNMA_00012	3.42e-195	mutR	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HFLCNNMA_00013	9.42e-203	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
HFLCNNMA_00014	1.67e-123	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
HFLCNNMA_00015	5.3e-264	ysdE	-	-	P	-	-	-	Citrate transporter
HFLCNNMA_00016	5.79e-23	-	-	-	-	-	-	-	-
HFLCNNMA_00017	1.13e-221	-	-	-	L	-	-	-	HNH nucleases
HFLCNNMA_00018	1.32e-152	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
HFLCNNMA_00019	2.81e-181	glnQ	-	-	E	ko:K17076	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HFLCNNMA_00020	0.0	XK27_05795	-	-	P	ko:K17073,ko:K17074	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HFLCNNMA_00021	6.22e-158	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
HFLCNNMA_00022	9.2e-87	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
HFLCNNMA_00023	2.93e-168	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
HFLCNNMA_00024	1.43e-105	-	-	-	-	-	-	-	-
HFLCNNMA_00025	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HFLCNNMA_00026	1.9e-230	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HFLCNNMA_00027	1.37e-173	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HFLCNNMA_00028	8.04e-209	-	-	-	S	-	-	-	Protein of unknown function (DUF1002)
HFLCNNMA_00029	2.85e-205	epsV	-	-	S	-	-	-	glycosyl transferase family 2
HFLCNNMA_00030	1.92e-162	-	-	-	S	-	-	-	Alpha/beta hydrolase family
HFLCNNMA_00031	1.03e-237	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HFLCNNMA_00032	1.83e-159	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HFLCNNMA_00033	1.67e-185	-	-	-	-	-	-	-	-
HFLCNNMA_00034	2.41e-150	crp2	-	-	K	ko:K10914,ko:K21562	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
HFLCNNMA_00035	3.59e-263	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
HFLCNNMA_00036	4.03e-263	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HFLCNNMA_00038	6.42e-243	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
HFLCNNMA_00039	1.98e-166	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
HFLCNNMA_00040	4.6e-218	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HFLCNNMA_00041	1.46e-109	dexB	3.2.1.70	-	G	ko:K01215	-	ko00000,ko01000	Alpha amylase, catalytic domain protein
HFLCNNMA_00042	2.03e-127	malF	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HFLCNNMA_00043	2.65e-186	malG	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HFLCNNMA_00044	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
HFLCNNMA_00045	6.17e-284	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HFLCNNMA_00046	2.59e-116	ntd	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside
HFLCNNMA_00047	3.14e-109	-	2.7.1.200, 2.7.1.204	-	G	ko:K02773,ko:K20112	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HFLCNNMA_00048	8.73e-191	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HFLCNNMA_00049	3.83e-109	usp5	-	-	T	-	-	-	universal stress protein
HFLCNNMA_00050	4.89e-212	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
HFLCNNMA_00051	2.39e-179	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HFLCNNMA_00052	2.63e-172	phnB	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HFLCNNMA_00053	5.24e-190	-	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HFLCNNMA_00054	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HFLCNNMA_00055	3e-108	-	-	-	-	-	-	-	-
HFLCNNMA_00056	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HFLCNNMA_00057	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HFLCNNMA_00058	5.46e-315	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
HFLCNNMA_00059	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
HFLCNNMA_00060	7.21e-182	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HFLCNNMA_00061	2.49e-27	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HFLCNNMA_00062	2.47e-27	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HFLCNNMA_00063	1.22e-113	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
HFLCNNMA_00064	5.06e-62	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
HFLCNNMA_00065	3.77e-288	yqjV	-	-	EGP	-	-	-	Major Facilitator Superfamily
HFLCNNMA_00066	2.18e-82	-	-	-	O	-	-	-	Glutaredoxin-related protein
HFLCNNMA_00067	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
HFLCNNMA_00068	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HFLCNNMA_00069	2.42e-96	-	-	-	-	-	-	-	-
HFLCNNMA_00070	2.96e-175	-	-	-	-	-	-	-	-
HFLCNNMA_00071	1.23e-39	-	-	-	-	-	-	-	-
HFLCNNMA_00072	6.35e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
HFLCNNMA_00073	1.24e-228	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HFLCNNMA_00074	0.0	-	3.2.1.96, 3.5.1.28	GH73	M	ko:K01227,ko:K01447,ko:K13714,ko:K13731	ko00511,ko05100,map00511,map05100	ko00000,ko00001,ko01000	N-acetylmuramoyl-L-alanine amidase
HFLCNNMA_00075	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
HFLCNNMA_00076	2.6e-93	-	-	-	S	-	-	-	Oxidoreductase
HFLCNNMA_00077	7.96e-170	-	-	-	-	-	-	-	-
HFLCNNMA_00078	2.71e-167	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HFLCNNMA_00079	9.16e-272	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HFLCNNMA_00080	2.71e-24	plsY1	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HFLCNNMA_00081	4.15e-93	plsY1	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HFLCNNMA_00082	0.0	XK27_08315	-	-	M	-	-	-	Sulfatase
HFLCNNMA_00083	1.68e-70	-	-	-	S	-	-	-	Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units
HFLCNNMA_00084	5.61e-99	-	-	-	L	-	-	-	DDE superfamily endonuclease
HFLCNNMA_00085	2.15e-103	-	-	-	L	-	-	-	DDE superfamily endonuclease
HFLCNNMA_00086	5.42e-32	-	-	-	L	-	-	-	Transposase
HFLCNNMA_00087	3.45e-25	nth2	-	-	L	ko:K07457	-	ko00000	Base excision DNA repair protein, HhH-GPD family
HFLCNNMA_00088	8.76e-75	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HFLCNNMA_00089	1.06e-260	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
HFLCNNMA_00090	0.0	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HFLCNNMA_00091	7.12e-256	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydropteroate synthase
HFLCNNMA_00092	4.67e-127	-	3.6.1.67	-	F	ko:K19965	ko00790,map00790	ko00000,ko00001,ko00002,ko01000	NUDIX domain
HFLCNNMA_00093	1.32e-144	glnP9	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter, permease protein
HFLCNNMA_00094	1.39e-121	glnP7	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter permease
HFLCNNMA_00095	4.14e-175	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HFLCNNMA_00096	2.53e-205	cjaA	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
HFLCNNMA_00098	3.23e-308	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HFLCNNMA_00100	4.09e-80	-	-	-	S	ko:K07006	-	ko00000	Pyridoxamine 5'-phosphate oxidase
HFLCNNMA_00101	3.06e-123	steT	-	-	E	ko:K03294	-	ko00000	amino acid
HFLCNNMA_00102	2.29e-297	amd	-	-	E	-	-	-	Peptidase family M20/M25/M40
HFLCNNMA_00103	2.47e-164	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HFLCNNMA_00104	1.27e-311	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
HFLCNNMA_00105	9.11e-155	ypgQ	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HFLCNNMA_00106	9.42e-30	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HFLCNNMA_00107	3.11e-78	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HFLCNNMA_00108	4.26e-220	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HFLCNNMA_00109	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HFLCNNMA_00110	5.19e-42	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	transmembrane transport
HFLCNNMA_00111	4.15e-160	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HFLCNNMA_00112	4.42e-63	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HFLCNNMA_00113	1.03e-36	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HFLCNNMA_00114	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
HFLCNNMA_00115	1.09e-200	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HFLCNNMA_00116	3.19e-239	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HFLCNNMA_00117	2.78e-251	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HFLCNNMA_00118	1.09e-226	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HFLCNNMA_00119	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
HFLCNNMA_00120	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Papain family cysteine protease
HFLCNNMA_00121	6.11e-96	-	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HFLCNNMA_00122	2.07e-102	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HFLCNNMA_00123	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HFLCNNMA_00124	4.21e-242	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HFLCNNMA_00125	0.0	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
HFLCNNMA_00126	6.71e-85	-	-	-	-	-	-	-	-
HFLCNNMA_00127	3.79e-291	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
HFLCNNMA_00128	2.76e-129	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HFLCNNMA_00129	2.95e-263	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HFLCNNMA_00130	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
HFLCNNMA_00131	5.02e-52	-	-	-	S	-	-	-	HicA toxin of bacterial toxin-antitoxin,
HFLCNNMA_00132	7.29e-84	-	-	-	S	-	-	-	HicB family
HFLCNNMA_00133	0.0	-	-	-	KLT	-	-	-	Protein kinase domain
HFLCNNMA_00134	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
HFLCNNMA_00135	5.11e-180	-	-	-	K	-	-	-	Transcriptional regulator
HFLCNNMA_00136	5.1e-303	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HFLCNNMA_00139	4.74e-177	fliY	-	-	ET	ko:K02030,ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
HFLCNNMA_00140	6.82e-171	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HFLCNNMA_00141	3.63e-165	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HFLCNNMA_00143	7.71e-165	-	-	-	F	-	-	-	Phosphorylase superfamily
HFLCNNMA_00144	0.0	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
HFLCNNMA_00145	1.41e-215	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
HFLCNNMA_00146	3.57e-60	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HFLCNNMA_00147	2.44e-141	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HFLCNNMA_00148	5.83e-223	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
HFLCNNMA_00149	1.75e-11	-	-	-	S	-	-	-	Aminoacyl-tRNA editing domain
HFLCNNMA_00150	7.43e-68	-	-	-	S	-	-	-	Aminoacyl-tRNA editing domain
HFLCNNMA_00151	5.71e-08	tyrA	1.3.1.12, 5.4.99.5	-	E	ko:K14187	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	chorismate mutase
HFLCNNMA_00152	4.05e-98	-	-	-	K	-	-	-	DNA-binding transcription factor activity
HFLCNNMA_00153	1.45e-239	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase, type I
HFLCNNMA_00154	4.69e-10	-	-	-	Q	-	-	-	phosphatase activity
HFLCNNMA_00155	3.06e-119	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HFLCNNMA_00156	8.99e-104	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HFLCNNMA_00157	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HFLCNNMA_00158	4.51e-25	-	-	-	L	-	-	-	transposase and inactivated derivatives, IS30 family
HFLCNNMA_00159	1.95e-113	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HFLCNNMA_00160	3.73e-69	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HFLCNNMA_00161	4.64e-139	pncA	-	-	Q	-	-	-	Isochorismatase family
HFLCNNMA_00162	2.87e-151	-	-	-	-	-	-	-	-
HFLCNNMA_00163	1.9e-56	-	-	-	L	-	-	-	Membrane
HFLCNNMA_00164	2.32e-187	-	-	-	F	-	-	-	NUDIX domain
HFLCNNMA_00165	1.14e-38	-	-	-	S	-	-	-	Enterocin A Immunity
HFLCNNMA_00167	3.74e-149	-	-	-	E	-	-	-	peptidase
HFLCNNMA_00168	5.53e-174	-	-	-	V	-	-	-	ABC-2 type transporter
HFLCNNMA_00169	6.61e-167	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HFLCNNMA_00170	2.71e-07	-	-	-	KLT	-	-	-	Protein tyrosine kinase
HFLCNNMA_00171	4.83e-153	-	-	-	-	-	-	-	-
HFLCNNMA_00173	9.25e-247	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HFLCNNMA_00174	2.79e-117	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	MafB19-like deaminase
HFLCNNMA_00175	7.13e-134	-	-	-	S	ko:K06872	-	ko00000	TPM domain
HFLCNNMA_00176	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
HFLCNNMA_00177	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HFLCNNMA_00178	5.49e-191	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
HFLCNNMA_00179	3.34e-126	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HFLCNNMA_00180	1.57e-204	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HFLCNNMA_00181	4.13e-51	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
HFLCNNMA_00182	4.31e-192	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
HFLCNNMA_00183	0.0	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HFLCNNMA_00184	7.9e-60	-	-	-	-	-	-	-	-
HFLCNNMA_00185	1.27e-225	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HFLCNNMA_00186	0.0	-	-	-	S	ko:K06885	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HFLCNNMA_00187	1.73e-84	-	-	-	S	-	-	-	Domain of unknown function (DUF1934)
HFLCNNMA_00188	3.45e-91	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HFLCNNMA_00189	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HFLCNNMA_00190	1.26e-306	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HFLCNNMA_00191	3.27e-55	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
HFLCNNMA_00192	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HFLCNNMA_00193	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HFLCNNMA_00194	3.58e-93	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HFLCNNMA_00195	1.62e-276	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HFLCNNMA_00196	9.02e-163	-	-	-	S	-	-	-	(CBS) domain
HFLCNNMA_00197	5.2e-132	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HFLCNNMA_00198	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HFLCNNMA_00199	1.48e-45	yabO	-	-	J	-	-	-	S4 domain protein
HFLCNNMA_00200	1.99e-78	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
HFLCNNMA_00201	4.32e-80	-	-	-	J	ko:K07571	-	ko00000	S1 RNA binding domain
HFLCNNMA_00202	0.0	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HFLCNNMA_00203	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HFLCNNMA_00204	2.85e-210	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HFLCNNMA_00205	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HFLCNNMA_00206	0.0	yqjE	3.4.11.14, 3.4.11.4	-	E	ko:K01258,ko:K01263	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HFLCNNMA_00207	2.57e-250	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HFLCNNMA_00208	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HFLCNNMA_00210	2.95e-72	-	-	-	T	ko:K03320	-	ko00000,ko02000	GGDEF domain
HFLCNNMA_00211	1.79e-81	-	-	-	T	ko:K03320	-	ko00000,ko02000	GGDEF domain
HFLCNNMA_00213	4.18e-31	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	o-acetylhomoserine
HFLCNNMA_00214	2.39e-276	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
HFLCNNMA_00215	3.88e-140	XK27_00160	-	-	S	-	-	-	Domain of unknown function (DUF5052)
HFLCNNMA_00219	9.11e-106	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
HFLCNNMA_00220	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HFLCNNMA_00223	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HFLCNNMA_00224	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HFLCNNMA_00226	7.5e-19	-	-	-	Q	-	-	-	phosphatase activity
HFLCNNMA_00227	2.96e-91	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HFLCNNMA_00228	6.89e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HFLCNNMA_00229	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HFLCNNMA_00230	1.55e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
HFLCNNMA_00231	3.42e-142	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HFLCNNMA_00232	6.65e-138	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
HFLCNNMA_00233	1.72e-59	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HFLCNNMA_00234	2.82e-198	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HFLCNNMA_00235	1.79e-60	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HFLCNNMA_00236	3.7e-72	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HFLCNNMA_00237	3.28e-156	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HFLCNNMA_00238	8.89e-101	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HFLCNNMA_00239	9.34e-34	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
HFLCNNMA_00240	1.34e-56	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HFLCNNMA_00241	1.73e-77	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HFLCNNMA_00242	5.64e-45	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HFLCNNMA_00243	1.75e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HFLCNNMA_00244	9.28e-89	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HFLCNNMA_00245	2.92e-120	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HFLCNNMA_00246	1.55e-74	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HFLCNNMA_00247	4.52e-112	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HFLCNNMA_00248	1.1e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
HFLCNNMA_00249	5.15e-95	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HFLCNNMA_00250	5.33e-303	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HFLCNNMA_00251	6.92e-155	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HFLCNNMA_00252	3.13e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HFLCNNMA_00253	5.08e-74	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HFLCNNMA_00254	6.6e-83	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HFLCNNMA_00255	2.66e-220	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HFLCNNMA_00256	1.91e-81	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HFLCNNMA_00257	4.69e-199	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HFLCNNMA_00258	1.41e-207	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HFLCNNMA_00259	6.07e-182	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HFLCNNMA_00260	8.77e-194	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HFLCNNMA_00261	1.54e-101	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HFLCNNMA_00262	9.68e-86	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
HFLCNNMA_00263	5.07e-61	-	-	-	-	-	-	-	-
HFLCNNMA_00264	5.58e-150	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HFLCNNMA_00265	3.08e-23	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HFLCNNMA_00266	5.57e-73	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HFLCNNMA_00267	8.82e-155	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
HFLCNNMA_00268	4.49e-45	-	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
HFLCNNMA_00269	8.27e-78	-	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
HFLCNNMA_00270	4.3e-86	-	-	-	EGP	-	-	-	Major Facilitator
HFLCNNMA_00271	1.8e-119	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
HFLCNNMA_00274	8.51e-286	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HFLCNNMA_00275	5.09e-224	pfoSR	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
HFLCNNMA_00278	1.2e-98	oppA2	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HFLCNNMA_00279	6.54e-273	-	-	-	-	-	-	-	-
HFLCNNMA_00280	3.41e-256	-	-	-	-	-	-	-	-
HFLCNNMA_00281	8.01e-162	gntR1	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
HFLCNNMA_00282	3.43e-284	-	-	-	M	-	-	-	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HFLCNNMA_00283	0.0	epsU	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HFLCNNMA_00284	1.19e-173	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HFLCNNMA_00285	3.56e-259	-	-	-	M	-	-	-	Glycosyl transferases group 1
HFLCNNMA_00286	2.07e-173	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
HFLCNNMA_00287	3.16e-194	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HFLCNNMA_00288	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HFLCNNMA_00292	1.3e-137	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HFLCNNMA_00293	1.48e-119	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
HFLCNNMA_00295	1.13e-130	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
HFLCNNMA_00296	6.12e-149	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
HFLCNNMA_00297	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
HFLCNNMA_00298	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HFLCNNMA_00299	8.06e-259	camS	-	-	S	-	-	-	sex pheromone
HFLCNNMA_00300	3.99e-64	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HFLCNNMA_00301	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HFLCNNMA_00302	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HFLCNNMA_00303	5.36e-218	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
HFLCNNMA_00304	1.26e-157	ybbB	-	-	S	-	-	-	Protein of unknown function (DUF1211)
HFLCNNMA_00305	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HFLCNNMA_00306	3.53e-188	-	-	-	L	ko:K07448	-	ko00000,ko02048	Mrr N-terminal domain
HFLCNNMA_00307	4.36e-155	-	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	Eukaryotic-type carbonic anhydrase
HFLCNNMA_00308	1.31e-185	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HFLCNNMA_00309	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
HFLCNNMA_00310	1.04e-45	copZ	-	-	P	-	-	-	Heavy-metal-associated domain
HFLCNNMA_00311	1.99e-62	-	-	-	D	-	-	-	Di-iron-containing protein involved in the repair of iron-sulfur clusters
HFLCNNMA_00312	4.47e-146	-	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
HFLCNNMA_00313	1.26e-304	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HFLCNNMA_00314	1.57e-157	alkD	-	-	L	-	-	-	DNA alkylation repair enzyme
HFLCNNMA_00315	1.65e-122	-	3.6.1.22	-	L	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	ko00000,ko00001,ko01000	NUDIX domain
HFLCNNMA_00316	5.56e-100	-	-	-	T	-	-	-	Gaf domain
HFLCNNMA_00318	1.17e-34	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HFLCNNMA_00319	2.21e-69	-	-	-	S	ko:K08987	-	ko00000	membrane
HFLCNNMA_00320	3.25e-112	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	AsnC family
HFLCNNMA_00321	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HFLCNNMA_00322	6.31e-68	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	transcriptional antiterminator
HFLCNNMA_00323	4.6e-10	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
HFLCNNMA_00324	2.13e-85	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
HFLCNNMA_00325	0.0	ppc	4.1.1.31	-	H	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HFLCNNMA_00326	2.08e-71	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HFLCNNMA_00327	6.09e-122	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HFLCNNMA_00328	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
HFLCNNMA_00329	7.41e-128	proP	-	-	EGP	ko:K03761,ko:K03762	-	ko00000,ko02000	Sugar (and other) transporter
HFLCNNMA_00330	1.21e-56	proP	-	-	EGP	ko:K03761,ko:K03762	-	ko00000,ko02000	Sugar (and other) transporter
HFLCNNMA_00332	3.11e-75	-	-	-	-	-	-	-	-
HFLCNNMA_00333	9.33e-274	pmrA	-	-	EGP	ko:K08161	-	ko00000,ko02000	MFS_1 like family
HFLCNNMA_00334	4.56e-154	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HFLCNNMA_00335	5.43e-183	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HFLCNNMA_00336	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HFLCNNMA_00337	2.34e-266	pepA	-	-	E	-	-	-	M42 glutamyl aminopeptidase
HFLCNNMA_00338	2.02e-131	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
HFLCNNMA_00340	5.48e-143	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Zeta toxin
HFLCNNMA_00341	1.62e-149	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Zeta toxin
HFLCNNMA_00342	9.36e-172	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HFLCNNMA_00343	1.89e-192	glnH	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HFLCNNMA_00344	3.27e-142	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HFLCNNMA_00345	4.57e-142	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HFLCNNMA_00346	1.89e-193	-	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
HFLCNNMA_00347	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HFLCNNMA_00348	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HFLCNNMA_00349	1.1e-174	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
HFLCNNMA_00350	1.3e-140	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
HFLCNNMA_00352	1.46e-50	-	-	-	-	-	-	-	-
HFLCNNMA_00353	1.6e-114	-	-	-	-	-	-	-	-
HFLCNNMA_00354	7.49e-208	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HFLCNNMA_00355	3.05e-153	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
HFLCNNMA_00356	6.1e-160	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HFLCNNMA_00357	2.57e-222	rihC	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
HFLCNNMA_00358	3.82e-168	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
HFLCNNMA_00359	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
HFLCNNMA_00362	1.86e-316	yhdP	-	-	S	-	-	-	Transporter associated domain
HFLCNNMA_00363	3e-133	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
HFLCNNMA_00364	1.14e-292	-	-	-	E	ko:K03294	-	ko00000	amino acid
HFLCNNMA_00365	1.28e-160	lys	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HFLCNNMA_00366	5.3e-283	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
HFLCNNMA_00367	4.31e-313	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HFLCNNMA_00369	7.1e-234	pfoS/R	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
HFLCNNMA_00370	6.91e-297	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
HFLCNNMA_00371	2.15e-299	ynbB	-	-	P	-	-	-	aluminum resistance
HFLCNNMA_00372	0.0	speA	4.1.1.17, 4.1.1.18, 4.1.1.19	-	E	ko:K01581,ko:K01582,ko:K01585	ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Orn/Lys/Arg decarboxylase, C-terminal domain
HFLCNNMA_00374	1.13e-157	-	-	-	E	-	-	-	Amino acid permease
HFLCNNMA_00375	9.03e-173	-	-	-	E	-	-	-	Amino acid permease
HFLCNNMA_00376	7.82e-34	-	-	-	-	-	-	-	-
HFLCNNMA_00377	5.58e-270	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HFLCNNMA_00378	5e-106	gtcA1	-	-	S	-	-	-	Teichoic acid glycosylation protein
HFLCNNMA_00379	8.2e-102	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
HFLCNNMA_00380	3.34e-209	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
HFLCNNMA_00381	8.5e-213	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
HFLCNNMA_00382	1.87e-216	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HFLCNNMA_00384	4.5e-233	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
HFLCNNMA_00385	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HFLCNNMA_00386	1.89e-188	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
HFLCNNMA_00387	1.75e-110	-	-	-	-	-	-	-	-
HFLCNNMA_00388	2.48e-95	-	-	-	-	-	-	-	-
HFLCNNMA_00389	3.06e-202	hlyX	-	-	S	ko:K03699	-	ko00000,ko02042	Transporter associated domain
HFLCNNMA_00390	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HFLCNNMA_00391	9.06e-27	-	-	-	-	-	-	-	-
HFLCNNMA_00392	2.16e-260	sufI	-	-	Q	-	-	-	Multicopper oxidase
HFLCNNMA_00393	4.54e-59	XK27_09445	-	-	S	-	-	-	Domain of unknown function (DUF1827)
HFLCNNMA_00394	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
HFLCNNMA_00396	6.14e-53	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
HFLCNNMA_00397	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HFLCNNMA_00398	3.22e-90	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HFLCNNMA_00399	5e-173	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HFLCNNMA_00400	4.74e-210	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
HFLCNNMA_00401	3.15e-145	yjbH	-	-	Q	-	-	-	Thioredoxin
HFLCNNMA_00402	4.73e-140	-	-	-	S	-	-	-	CYTH
HFLCNNMA_00403	3.84e-145	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
HFLCNNMA_00404	7.48e-192	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HFLCNNMA_00405	8.2e-220	rluD2	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HFLCNNMA_00406	7.7e-31	-	-	-	-	-	-	-	-
HFLCNNMA_00407	3.66e-188	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HFLCNNMA_00408	2.89e-252	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
HFLCNNMA_00409	1.11e-84	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
HFLCNNMA_00410	5.85e-255	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
HFLCNNMA_00411	2.21e-133	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HFLCNNMA_00412	1.81e-90	-	-	-	S	-	-	-	Protein of unknown function (DUF1149)
HFLCNNMA_00413	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HFLCNNMA_00414	7.67e-293	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
HFLCNNMA_00415	3.44e-301	ymfH	-	-	S	-	-	-	Peptidase M16
HFLCNNMA_00416	1.33e-169	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
HFLCNNMA_00417	8.57e-161	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
HFLCNNMA_00418	1.87e-126	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HFLCNNMA_00419	1.13e-252	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HFLCNNMA_00420	6.72e-284	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
HFLCNNMA_00421	1.88e-273	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
HFLCNNMA_00422	2.7e-153	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
HFLCNNMA_00423	1.38e-311	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
HFLCNNMA_00424	1.1e-155	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
HFLCNNMA_00425	2.28e-126	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HFLCNNMA_00426	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HFLCNNMA_00427	2.24e-238	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HFLCNNMA_00428	2.72e-57	-	-	-	-	-	-	-	-
HFLCNNMA_00429	2.12e-222	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HFLCNNMA_00430	9.5e-201	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HFLCNNMA_00431	5.53e-242	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
HFLCNNMA_00432	2.48e-224	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HFLCNNMA_00433	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HFLCNNMA_00434	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HFLCNNMA_00435	9.33e-119	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
HFLCNNMA_00436	2.61e-188	dppA	-	-	E	ko:K16203	-	ko00000,ko01000,ko01002	D-aminopeptidase
HFLCNNMA_00437	6.08e-107	dmpA	3.4.11.19	-	EQ	ko:K01266	-	ko00000,ko01000,ko01002	Peptidase family S58
HFLCNNMA_00438	1.16e-209	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
HFLCNNMA_00439	1.47e-242	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
HFLCNNMA_00440	1.79e-217	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
HFLCNNMA_00441	1.21e-130	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HFLCNNMA_00442	6.63e-294	-	-	-	-	-	-	-	-
HFLCNNMA_00443	5.47e-47	-	-	-	-	-	-	-	-
HFLCNNMA_00444	1.98e-40	ABC-SBP	-	-	S	ko:K01989,ko:K05832	-	ko00000,ko00002,ko02000	ABC transporter substrate binding protein
HFLCNNMA_00445	2.35e-68	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
HFLCNNMA_00446	1.89e-13	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
HFLCNNMA_00447	1.08e-39	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HFLCNNMA_00448	6.81e-123	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HFLCNNMA_00449	1.38e-114	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HFLCNNMA_00450	1e-28	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HFLCNNMA_00452	6.25e-268	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
HFLCNNMA_00453	4.06e-244	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HFLCNNMA_00454	2.86e-286	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
HFLCNNMA_00455	3.16e-182	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HFLCNNMA_00456	2.01e-34	-	-	-	K	ko:K06977	-	ko00000	acetyltransferase
HFLCNNMA_00457	4.9e-64	-	-	-	K	ko:K06977	-	ko00000	acetyltransferase
HFLCNNMA_00458	3.12e-135	-	-	-	-	-	-	-	-
HFLCNNMA_00459	3.86e-204	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HFLCNNMA_00460	1.77e-171	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HFLCNNMA_00461	3.84e-233	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
HFLCNNMA_00462	1.13e-112	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
HFLCNNMA_00463	9.43e-127	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HFLCNNMA_00464	5.08e-206	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
HFLCNNMA_00465	6.4e-260	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HFLCNNMA_00466	9.32e-184	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HFLCNNMA_00467	1.71e-173	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HFLCNNMA_00468	4.19e-264	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HFLCNNMA_00469	1.1e-191	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HFLCNNMA_00470	6.44e-214	ybbR	-	-	S	-	-	-	YbbR-like protein
HFLCNNMA_00471	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HFLCNNMA_00472	3.69e-190	-	-	-	S	-	-	-	hydrolase
HFLCNNMA_00473	5.26e-139	-	-	-	V	-	-	-	Beta-lactamase
HFLCNNMA_00474	2.1e-99	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
HFLCNNMA_00475	1.3e-82	-	-	-	S	-	-	-	Cupredoxin-like domain
HFLCNNMA_00476	0.0	copA	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
HFLCNNMA_00477	9.05e-85	crcB1	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HFLCNNMA_00478	2.39e-78	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HFLCNNMA_00479	4.25e-24	-	-	-	-	-	-	-	-
HFLCNNMA_00480	4.7e-124	-	-	-	-	-	-	-	-
HFLCNNMA_00481	1.3e-151	-	-	-	T	-	-	-	diguanylate cyclase activity
HFLCNNMA_00482	3.94e-230	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HFLCNNMA_00483	0.0	-	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
HFLCNNMA_00485	3.45e-86	-	-	-	-	-	-	-	-
HFLCNNMA_00486	2.62e-109	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HFLCNNMA_00487	4.25e-85	-	-	-	GM	-	-	-	epimerase
HFLCNNMA_00488	0.0	-	-	-	E	-	-	-	Amino acid permease
HFLCNNMA_00489	1.7e-132	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HFLCNNMA_00490	1.55e-201	-	-	-	S	-	-	-	Phospholipase, patatin family
HFLCNNMA_00491	1.11e-207	psaA	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HFLCNNMA_00492	2.32e-121	-	-	-	S	-	-	-	VanZ like family
HFLCNNMA_00493	1.01e-169	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
HFLCNNMA_00494	3.28e-231	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
HFLCNNMA_00495	5.81e-209	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
HFLCNNMA_00496	2.72e-67	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
HFLCNNMA_00497	6.05e-98	-	-	-	-	ko:K02246	-	ko00000,ko00002,ko02044	-
HFLCNNMA_00500	2.51e-235	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
HFLCNNMA_00501	4.9e-283	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HFLCNNMA_00504	7.74e-173	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
HFLCNNMA_00505	0.0	yclK	-	-	T	-	-	-	Histidine kinase
HFLCNNMA_00506	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HFLCNNMA_00507	1.2e-146	vanZ	-	-	V	-	-	-	VanZ like family
HFLCNNMA_00508	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HFLCNNMA_00509	7.63e-112	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HFLCNNMA_00510	6.39e-227	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HFLCNNMA_00513	2.97e-244	ampC	-	-	V	-	-	-	Beta-lactamase
HFLCNNMA_00514	3.69e-45	-	-	-	-	-	-	-	-
HFLCNNMA_00515	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Mur ligase, middle domain
HFLCNNMA_00516	8.86e-145	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
HFLCNNMA_00517	2.77e-249	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HFLCNNMA_00518	5.7e-199	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HFLCNNMA_00519	9.18e-242	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HFLCNNMA_00520	3.18e-147	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HFLCNNMA_00521	9.32e-164	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HFLCNNMA_00522	7.13e-39	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HFLCNNMA_00523	6.38e-102	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HFLCNNMA_00524	2.39e-121	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HFLCNNMA_00525	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HFLCNNMA_00526	1.66e-218	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HFLCNNMA_00527	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HFLCNNMA_00528	3.63e-95	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HFLCNNMA_00529	7.57e-44	-	-	-	S	-	-	-	Protein of unknown function (DUF1146)
HFLCNNMA_00530	5.61e-226	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
HFLCNNMA_00531	4.4e-64	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
HFLCNNMA_00532	1.04e-45	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
HFLCNNMA_00533	2.41e-279	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
HFLCNNMA_00534	2.07e-102	uspA	-	-	T	-	-	-	universal stress protein
HFLCNNMA_00535	1.02e-56	-	-	-	-	-	-	-	-
HFLCNNMA_00536	5.39e-309	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
HFLCNNMA_00537	9.83e-106	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HFLCNNMA_00538	3.59e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HFLCNNMA_00539	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HFLCNNMA_00540	1.89e-275	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HFLCNNMA_00541	9.32e-293	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HFLCNNMA_00542	2.38e-167	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HFLCNNMA_00543	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HFLCNNMA_00544	1.57e-299	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HFLCNNMA_00545	2.82e-163	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HFLCNNMA_00546	5.32e-148	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
HFLCNNMA_00547	9.63e-225	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
HFLCNNMA_00548	5.34e-176	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
HFLCNNMA_00549	1.97e-124	mreD	-	-	-	ko:K03571	-	ko00000,ko03036	-
HFLCNNMA_00551	2.49e-73	-	-	-	S	-	-	-	Protein of unknown function (DUF3397)
HFLCNNMA_00552	4.45e-99	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HFLCNNMA_00553	2.66e-221	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HFLCNNMA_00554	1.14e-71	ftsL	-	-	D	-	-	-	Cell division protein FtsL
HFLCNNMA_00555	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HFLCNNMA_00556	4.46e-227	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HFLCNNMA_00557	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HFLCNNMA_00558	2.35e-266	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HFLCNNMA_00559	6.07e-190	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HFLCNNMA_00560	0.0	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HFLCNNMA_00561	5.99e-305	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HFLCNNMA_00562	3.21e-99	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HFLCNNMA_00563	7.21e-62	yggT	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
HFLCNNMA_00564	1.14e-186	ylmH	-	-	S	-	-	-	S4 domain protein
HFLCNNMA_00565	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HFLCNNMA_00566	3.24e-44	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
HFLCNNMA_00567	3.66e-132	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
HFLCNNMA_00568	3.72e-36	-	-	-	-	-	-	-	-
HFLCNNMA_00569	1.56e-163	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HFLCNNMA_00570	3.66e-274	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HFLCNNMA_00571	2.45e-75	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
HFLCNNMA_00572	3.28e-280	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HFLCNNMA_00573	7.5e-160	pgm	-	-	G	-	-	-	Phosphoglycerate mutase family
HFLCNNMA_00574	3.54e-148	-	-	-	S	-	-	-	repeat protein
HFLCNNMA_00575	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HFLCNNMA_00576	4.63e-316	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
HFLCNNMA_00577	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HFLCNNMA_00578	3.04e-48	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
HFLCNNMA_00579	8.33e-133	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HFLCNNMA_00580	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
HFLCNNMA_00581	3.93e-271	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HFLCNNMA_00582	1.31e-70	ylbG	-	-	S	-	-	-	UPF0298 protein
HFLCNNMA_00583	5.62e-126	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
HFLCNNMA_00584	1.53e-107	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HFLCNNMA_00585	1.53e-243	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
HFLCNNMA_00586	9.17e-118	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
HFLCNNMA_00587	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
HFLCNNMA_00588	1.5e-230	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
HFLCNNMA_00589	2.09e-44	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
HFLCNNMA_00590	1.01e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HFLCNNMA_00591	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HFLCNNMA_00592	5.43e-190	-	-	-	-	-	-	-	-
HFLCNNMA_00593	7.85e-285	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HFLCNNMA_00594	1.35e-300	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HFLCNNMA_00595	1.83e-296	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HFLCNNMA_00596	3.33e-140	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
HFLCNNMA_00597	0.0	-	-	-	I	-	-	-	Protein of unknown function (DUF2974)
HFLCNNMA_00598	2.77e-08	-	-	-	-	-	-	-	-
HFLCNNMA_00599	2.07e-162	pnb	-	-	C	-	-	-	nitroreductase
HFLCNNMA_00601	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HFLCNNMA_00602	1.03e-84	-	-	-	-	-	-	-	-
HFLCNNMA_00603	1.22e-151	-	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HFLCNNMA_00604	2.34e-242	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HFLCNNMA_00605	1.88e-116	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HFLCNNMA_00606	0.0	aha1	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
HFLCNNMA_00607	7.79e-168	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HFLCNNMA_00608	6.62e-236	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HFLCNNMA_00609	1.03e-150	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HFLCNNMA_00610	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HFLCNNMA_00611	2.67e-241	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
HFLCNNMA_00612	2.47e-149	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
HFLCNNMA_00613	2.91e-196	-	-	-	S	-	-	-	Protein of unknown function (DUF3298)
HFLCNNMA_00614	1.13e-127	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70 region 2
HFLCNNMA_00615	0.0	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HFLCNNMA_00616	1.95e-119	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HFLCNNMA_00617	4.92e-136	-	-	-	S	-	-	-	SNARE associated Golgi protein
HFLCNNMA_00618	5.49e-195	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HFLCNNMA_00619	1.15e-201	plcR	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
HFLCNNMA_00620	1.32e-122	-	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside 2-deoxyribosyltransferase
HFLCNNMA_00621	3.44e-167	-	-	-	F	-	-	-	glutamine amidotransferase
HFLCNNMA_00622	3.39e-253	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
HFLCNNMA_00623	4.53e-227	-	-	-	-	-	-	-	-
HFLCNNMA_00624	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
HFLCNNMA_00625	9.52e-128	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HFLCNNMA_00626	2.11e-34	-	-	-	-	-	-	-	-
HFLCNNMA_00627	1.69e-203	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
HFLCNNMA_00628	1.63e-206	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HFLCNNMA_00629	1.5e-144	pepI	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HFLCNNMA_00630	2.02e-61	pepI	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HFLCNNMA_00631	2.94e-106	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HFLCNNMA_00632	5.14e-137	-	-	-	-	-	-	-	-
HFLCNNMA_00633	1.19e-56	-	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	dipeptidase activity
HFLCNNMA_00634	1.8e-127	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
HFLCNNMA_00635	1.52e-201	dkgB	-	-	S	-	-	-	reductase
HFLCNNMA_00637	2.33e-43	-	-	-	GK	-	-	-	ROK family
HFLCNNMA_00638	2.48e-62	-	-	-	GK	-	-	-	ROK family
HFLCNNMA_00640	2.38e-88	-	-	-	S	-	-	-	PAS domain
HFLCNNMA_00641	2.76e-42	-	-	-	S	-	-	-	PAS domain
HFLCNNMA_00642	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
HFLCNNMA_00643	3.07e-196	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
HFLCNNMA_00644	1.11e-25	-	-	-	L	-	-	-	transposase and inactivated derivatives, IS30 family
HFLCNNMA_00645	3.13e-252	-	-	-	-	-	-	-	-
HFLCNNMA_00646	1.24e-230	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HFLCNNMA_00647	6.12e-102	-	-	-	S	-	-	-	Helix-turn-helix domain
HFLCNNMA_00648	4.8e-128	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HFLCNNMA_00649	1.01e-220	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
HFLCNNMA_00650	4.26e-133	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HFLCNNMA_00651	1.17e-96	-	-	-	K	-	-	-	LytTr DNA-binding domain
HFLCNNMA_00653	2.48e-92	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
HFLCNNMA_00654	1.11e-62	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
HFLCNNMA_00655	2.78e-55	-	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
HFLCNNMA_00656	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HFLCNNMA_00657	2.58e-147	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
HFLCNNMA_00658	1.58e-160	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
HFLCNNMA_00659	1.35e-172	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
HFLCNNMA_00661	0.0	-	3.1.4.46, 3.2.1.99	GH43	N	ko:K01126,ko:K06113	ko00564,map00564	ko00000,ko00001,ko01000	domain, Protein
HFLCNNMA_00662	1.5e-16	-	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphodiester phosphodiesterase activity
HFLCNNMA_00664	1.49e-149	-	-	-	L	-	-	-	DNA synthesis involved in DNA repair
HFLCNNMA_00665	6.16e-21	-	-	-	L	-	-	-	DNA synthesis involved in DNA repair
HFLCNNMA_00666	3.68e-73	-	-	-	L	-	-	-	DNA synthesis involved in DNA repair
HFLCNNMA_00667	1.01e-165	-	-	-	S	-	-	-	VanZ like family
HFLCNNMA_00668	3.27e-96	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
HFLCNNMA_00669	1.59e-104	-	-	-	-	-	-	-	-
HFLCNNMA_00670	7.85e-12	-	-	-	M	-	-	-	NlpC/P60 family
HFLCNNMA_00671	1.81e-112	-	-	-	M	-	-	-	NlpC/P60 family
HFLCNNMA_00673	1.85e-170	-	-	-	G	-	-	-	Peptidase_C39 like family
HFLCNNMA_00674	6.03e-248	-	-	-	S	-	-	-	Acyltransferase family
HFLCNNMA_00675	4.66e-93	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
HFLCNNMA_00676	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
HFLCNNMA_00677	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
HFLCNNMA_00678	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HFLCNNMA_00679	7.03e-216	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	GHMP kinases N terminal domain
HFLCNNMA_00680	1.22e-224	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
HFLCNNMA_00681	3.3e-261	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
HFLCNNMA_00682	2.27e-247	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HFLCNNMA_00683	2.02e-219	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
HFLCNNMA_00684	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HFLCNNMA_00685	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HFLCNNMA_00686	1.1e-144	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HFLCNNMA_00687	3.09e-56	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HFLCNNMA_00688	3.64e-154	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HFLCNNMA_00689	1.88e-75	-	-	-	V	ko:K06147	-	ko00000,ko02000	abc transporter atp-binding protein
HFLCNNMA_00690	3.51e-47	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HFLCNNMA_00691	4.65e-08	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HFLCNNMA_00692	7.52e-47	-	-	-	V	ko:K06147	-	ko00000,ko02000	(ABC) transporter
HFLCNNMA_00693	1.6e-12	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HFLCNNMA_00694	1.76e-191	-	-	-	G	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HFLCNNMA_00695	2.98e-135	-	-	-	-	-	-	-	-
HFLCNNMA_00696	1.88e-197	-	-	-	T	-	-	-	diguanylate cyclase
HFLCNNMA_00697	1.34e-286	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HFLCNNMA_00699	1.43e-135	-	-	-	T	ko:K16923	-	ko00000,ko00002,ko02000	phosphorelay sensor kinase activity
HFLCNNMA_00700	1.73e-173	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HFLCNNMA_00701	4.3e-190	-	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HFLCNNMA_00702	2.21e-179	-	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HFLCNNMA_00703	3.03e-53	-	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
HFLCNNMA_00704	5.43e-133	M1-740	-	-	I	-	-	-	NUDIX domain
HFLCNNMA_00705	2.26e-243	-	-	-	S	-	-	-	Glycosyl hydrolases family 18
HFLCNNMA_00706	3.17e-156	-	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
HFLCNNMA_00708	5.81e-73	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
HFLCNNMA_00709	5.46e-10	-	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter, ATP-binding protein
HFLCNNMA_00710	0.000856	ccmA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HFLCNNMA_00711	2.71e-28	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
HFLCNNMA_00712	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HFLCNNMA_00713	1.45e-160	phoB	-	-	T	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
HFLCNNMA_00714	1.98e-147	-	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
HFLCNNMA_00715	9.06e-182	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HFLCNNMA_00716	4.17e-202	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
HFLCNNMA_00717	5.27e-206	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HFLCNNMA_00718	8.71e-201	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HFLCNNMA_00721	1.44e-160	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HFLCNNMA_00722	2.26e-49	-	-	-	-	-	-	-	-
HFLCNNMA_00723	1.26e-98	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HFLCNNMA_00724	6.48e-140	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HFLCNNMA_00726	1.41e-33	-	-	-	L	-	-	-	DDE superfamily endonuclease
HFLCNNMA_00727	0.0	copB	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
HFLCNNMA_00728	1.47e-49	mdt(A)	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
HFLCNNMA_00729	1.68e-239	-	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
HFLCNNMA_00730	1.31e-311	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
HFLCNNMA_00731	7.89e-30	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
HFLCNNMA_00732	3.89e-227	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HFLCNNMA_00733	2.72e-65	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
HFLCNNMA_00734	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
HFLCNNMA_00735	3.14e-72	-	-	-	-	-	-	-	-
HFLCNNMA_00736	1.23e-34	-	-	-	-	-	-	-	-
HFLCNNMA_00738	0.0	-	-	-	V	ko:K07452	-	ko00000,ko01000,ko02048	AAA domain (dynein-related subfamily)
HFLCNNMA_00739	1.26e-216	-	-	-	V	ko:K19147	-	ko00000,ko02048	McrBC 5-methylcytosine restriction system component
HFLCNNMA_00740	1.85e-27	yeeC	-	-	P	-	-	-	T5orf172
HFLCNNMA_00741	1.79e-108	yeeC	-	-	P	-	-	-	T5orf172
HFLCNNMA_00742	8.73e-70	ogt	2.1.1.63	-	L	ko:K00567,ko:K13531	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HFLCNNMA_00743	1.49e-187	-	-	-	S	-	-	-	Peptidase family M23
HFLCNNMA_00744	8.58e-103	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
HFLCNNMA_00745	3.39e-157	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
HFLCNNMA_00746	2.24e-193	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HFLCNNMA_00747	2.75e-309	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HFLCNNMA_00748	3.04e-32	-	-	-	-	-	-	-	-
HFLCNNMA_00749	1.37e-133	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HFLCNNMA_00750	4.73e-206	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
HFLCNNMA_00751	2.11e-69	-	-	-	S	-	-	-	Alpha beta hydrolase
HFLCNNMA_00752	1e-93	thgA3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HFLCNNMA_00753	2.28e-96	-	-	-	L	-	-	-	DDE superfamily endonuclease
HFLCNNMA_00754	7.25e-173	-	-	-	L	-	-	-	DDE superfamily endonuclease
HFLCNNMA_00755	2.3e-98	-	-	-	L	-	-	-	COG3547 Transposase and inactivated derivatives
HFLCNNMA_00757	2.18e-30	-	-	-	L	-	-	-	DDE superfamily endonuclease
HFLCNNMA_00758	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
HFLCNNMA_00759	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
HFLCNNMA_00760	3.32e-62	-	-	-	K	ko:K02529	-	ko00000,ko03000	purine nucleotide biosynthetic process
HFLCNNMA_00761	1.24e-145	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HFLCNNMA_00762	1.92e-287	-	-	-	L	-	-	-	Transposase
HFLCNNMA_00763	1.46e-39	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
HFLCNNMA_00764	1.39e-17	-	1.3.8.1, 1.3.8.7	-	I	ko:K00248,ko:K00249,ko:K18244	ko00071,ko00280,ko00410,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map00650,map01100,map01110,map01120,map01130,map01200,map01212,map03320	ko00000,ko00001,ko00002,ko01000	Acyl-CoA dehydrogenase, C-terminal domain
HFLCNNMA_00765	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
HFLCNNMA_00766	0.0	mutS1	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HFLCNNMA_00767	3.97e-14	mutS1	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HFLCNNMA_00768	1.5e-166	-	-	-	-	-	-	-	-
HFLCNNMA_00769	4.04e-208	cpsY	-	-	K	-	-	-	Transcriptional regulator, LysR family
HFLCNNMA_00770	4.93e-197	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
HFLCNNMA_00771	2.71e-49	metK1	-	-	E	-	-	-	methionine synthase, vitamin-B12 independent
HFLCNNMA_00773	3.78e-220	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
HFLCNNMA_00774	4.37e-212	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HFLCNNMA_00775	2.73e-282	-	-	-	EGP	ko:K08196	-	ko00000,ko02000	Major Facilitator
HFLCNNMA_00776	3.15e-126	-	-	-	S	-	-	-	Membrane
HFLCNNMA_00777	5.86e-191	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HFLCNNMA_00778	6.06e-222	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
HFLCNNMA_00779	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HFLCNNMA_00780	7.52e-24	-	-	-	-	-	-	-	-
HFLCNNMA_00781	9.24e-213	arbZ	-	-	I	-	-	-	Phosphate acyltransferases
HFLCNNMA_00782	9.6e-149	-	-	-	M	-	-	-	Glycosyl transferase family 8
HFLCNNMA_00783	1.25e-199	arbx	-	-	M	-	-	-	Glycosyl transferase family 8
HFLCNNMA_00784	3.19e-194	-	-	-	I	-	-	-	Acyl-transferase
HFLCNNMA_00786	2.21e-168	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HFLCNNMA_00787	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HFLCNNMA_00788	1.6e-316	yycH	-	-	S	-	-	-	YycH protein
HFLCNNMA_00789	3.96e-183	yycI	-	-	S	-	-	-	YycH protein
HFLCNNMA_00790	3.05e-191	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
HFLCNNMA_00791	3.03e-238	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
HFLCNNMA_00792	3.52e-106	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HFLCNNMA_00796	5.35e-81	-	-	-	S	ko:K07006	-	ko00000	Pyridoxamine 5'-phosphate oxidase
HFLCNNMA_00797	1.87e-126	-	-	-	S	-	-	-	Cob(I)alamin adenosyltransferase
HFLCNNMA_00798	5.84e-123	-	-	-	S	ko:K16927	-	ko00000,ko00002,ko02000	ECF transporter, substrate-specific component
HFLCNNMA_00799	1.54e-11	-	-	-	S	-	-	-	Domain of unknown function (DUF4430)
HFLCNNMA_00800	0.0	rtpR	1.17.4.2	-	F	ko:K00527	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	ribonucleoside-triphosphate reductase activity
HFLCNNMA_00801	2.09e-208	yvgN	-	-	C	-	-	-	Aldo keto reductase
HFLCNNMA_00802	2.11e-221	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HFLCNNMA_00803	7.07e-97	-	-	-	-	-	-	-	-
HFLCNNMA_00804	3.75e-206	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HFLCNNMA_00805	8.87e-78	-	-	-	S	-	-	-	glycolate biosynthetic process
HFLCNNMA_00806	4.3e-22	nt5e	3.1.3.18	-	L	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	haloacid dehalogenase-like hydrolase
HFLCNNMA_00807	3.57e-176	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HFLCNNMA_00808	1.27e-81	-	-	-	L	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
HFLCNNMA_00809	7.63e-139	-	-	-	L	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
HFLCNNMA_00810	1.6e-115	-	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	biotin transmembrane transporter activity
HFLCNNMA_00811	3.19e-150	-	-	-	-	-	-	-	-
HFLCNNMA_00812	4.69e-17	-	-	-	-	-	-	-	-
HFLCNNMA_00813	1.92e-161	pgm7	-	-	G	-	-	-	Phosphoglycerate mutase family
HFLCNNMA_00814	3.76e-134	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HFLCNNMA_00815	1.62e-133	-	-	-	T	-	-	-	EAL domain
HFLCNNMA_00816	6.89e-188	yitS	-	-	S	-	-	-	EDD domain protein, DegV family
HFLCNNMA_00817	6.41e-118	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
HFLCNNMA_00818	6.42e-229	yfdH	-	GT2	M	ko:K12999,ko:K20534	-	ko00000,ko01000,ko01003,ko01005,ko02000	Glycosyltransferase like family 2
HFLCNNMA_00819	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
HFLCNNMA_00820	2.19e-186	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Sucrose glucosyltransferase
HFLCNNMA_00821	3.41e-171	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HFLCNNMA_00822	1.81e-109	-	-	-	K	-	-	-	DNA-templated transcription, initiation
HFLCNNMA_00824	4.13e-179	-	-	-	-	-	-	-	-
HFLCNNMA_00826	8.83e-39	scrK	2.7.1.2, 2.7.1.4	-	GK	ko:K00845,ko:K00847	ko00010,ko00051,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00051,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HFLCNNMA_00827	3.74e-241	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HFLCNNMA_00828	1.13e-40	bgl	3.2.1.21, 3.2.1.86	GT1	G	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	beta-glucosidase activity
HFLCNNMA_00830	3.78e-20	-	-	-	S	-	-	-	Gram-negative-bacterium-type cell wall biogenesis
HFLCNNMA_00831	7.36e-139	pat	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
HFLCNNMA_00832	9.38e-97	-	-	-	C	-	-	-	FMN_bind
HFLCNNMA_00833	4.98e-12	-	-	-	D	-	-	-	Filamentation induced by cAMP protein fic
HFLCNNMA_00835	9.12e-201	-	-	-	V	-	-	-	LD-carboxypeptidase
HFLCNNMA_00836	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
HFLCNNMA_00837	1.73e-222	-	-	-	-	-	-	-	-
HFLCNNMA_00838	1.76e-176	-	-	-	-	-	-	-	-
HFLCNNMA_00839	2.49e-35	-	-	-	-	-	-	-	-
HFLCNNMA_00840	3.33e-146	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HFLCNNMA_00841	4.14e-177	prsW	-	-	S	-	-	-	Involved in the degradation of specific anti-sigma factors
HFLCNNMA_00842	4.22e-131	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
HFLCNNMA_00843	2.63e-44	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
HFLCNNMA_00844	0.0	gapN	1.2.1.9	-	C	ko:K00131	ko00010,ko00030,ko01100,ko01120,ko01200,map00010,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HFLCNNMA_00845	0.0	-	-	-	EM	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HFLCNNMA_00846	3.49e-218	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HFLCNNMA_00847	4.87e-101	ywnA	-	-	K	-	-	-	Transcriptional regulator
HFLCNNMA_00848	5.95e-19	-	-	-	GM	-	-	-	NAD(P)H-binding
HFLCNNMA_00849	3.83e-120	-	-	-	GM	-	-	-	NmrA-like family
HFLCNNMA_00850	5.31e-211	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Peptidase family M48
HFLCNNMA_00851	5.58e-55	-	-	-	-	-	-	-	-
HFLCNNMA_00852	1.08e-288	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
HFLCNNMA_00853	0.0	prtP	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HFLCNNMA_00854	7.54e-99	-	-	-	K	-	-	-	GNAT family
HFLCNNMA_00855	1.27e-62	-	-	-	-	-	-	-	-
HFLCNNMA_00856	4.3e-36	-	-	-	-	-	-	-	-
HFLCNNMA_00857	1.32e-09	apl	3.1.3.1	-	S	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	SNARE associated Golgi protein
HFLCNNMA_00858	5.84e-253	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
HFLCNNMA_00860	4.12e-104	cydD1	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	abc transporter atp-binding protein
HFLCNNMA_00861	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
HFLCNNMA_00862	2.66e-97	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
HFLCNNMA_00863	8.85e-286	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HFLCNNMA_00864	2.93e-280	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
HFLCNNMA_00865	1.14e-183	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
HFLCNNMA_00866	9.11e-118	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HFLCNNMA_00867	3.95e-50	glvC	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HFLCNNMA_00868	3.71e-265	malH	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase C-terminal domain
HFLCNNMA_00869	6.69e-20	malH	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase C-terminal domain
HFLCNNMA_00871	2.2e-151	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HFLCNNMA_00872	5e-275	-	-	-	S	-	-	-	FtsX-like permease family
HFLCNNMA_00875	5.92e-102	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HFLCNNMA_00876	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HFLCNNMA_00877	1.3e-40	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HFLCNNMA_00878	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HFLCNNMA_00879	7.66e-228	mprF	-	-	S	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HFLCNNMA_00880	1.06e-256	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HFLCNNMA_00881	1.98e-279	-	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyl transferase 4-like domain
HFLCNNMA_00884	6.73e-72	luxA_2	-	-	C	-	-	-	Coenzyme F420-dependent N5N10-methylene tetrahydromethanopterin reductase
HFLCNNMA_00885	1.46e-56	-	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HFLCNNMA_00886	1.06e-234	-	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Rossmann-like domain
HFLCNNMA_00887	1.33e-75	-	-	-	K	-	-	-	sequence-specific DNA binding
HFLCNNMA_00888	1.15e-33	-	-	-	-	-	-	-	-
HFLCNNMA_00889	3.12e-50	-	-	-	-	-	-	-	-
HFLCNNMA_00890	9.97e-98	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
HFLCNNMA_00892	2.69e-255	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HFLCNNMA_00894	2.19e-152	rfbP	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
HFLCNNMA_00895	7.21e-191	cps3J	-	-	M	-	-	-	Domain of unknown function (DUF4422)
HFLCNNMA_00896	1.69e-280	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
HFLCNNMA_00897	5.38e-219	-	-	-	S	ko:K07011	-	ko00000	Glycosyltransferase like family 2
HFLCNNMA_00898	1.59e-233	epsF	-	GT4	M	ko:K19424	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HFLCNNMA_00899	4.81e-253	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HFLCNNMA_00900	0.0	epsIIL	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
HFLCNNMA_00901	1.39e-231	licD	-	-	M	ko:K07271	-	ko00000,ko01000	LicD family
HFLCNNMA_00902	3.17e-111	tagD	2.7.7.15, 2.7.7.39	-	IM	ko:K00968,ko:K00980	ko00440,ko00564,ko01100,ko05231,map00440,map00564,map01100,map05231	ko00000,ko00001,ko00002,ko01000	Glycerol-3-phosphate cytidylyltransferase
HFLCNNMA_00903	1.12e-287	-	-	-	-	-	-	-	-
HFLCNNMA_00905	3.53e-35	XK27_02085	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HFLCNNMA_00906	2.77e-131	-	-	-	L	-	-	-	nuclease
HFLCNNMA_00907	2.7e-198	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
HFLCNNMA_00908	8.62e-14	-	-	-	-	-	-	-	-
HFLCNNMA_00909	1.36e-109	-	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
HFLCNNMA_00910	1.36e-74	-	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
HFLCNNMA_00911	1.31e-193	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
HFLCNNMA_00912	6.56e-94	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
HFLCNNMA_00913	7.03e-58	dhaM	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	PTS system fructose IIA component
HFLCNNMA_00914	3.02e-162	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HFLCNNMA_00915	4.2e-75	XK27_02085	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HFLCNNMA_00916	2.57e-255	-	-	-	KQ	-	-	-	Hypothetical methyltransferase
HFLCNNMA_00917	1.11e-265	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HFLCNNMA_00918	1.68e-198	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HFLCNNMA_00919	7.88e-149	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HFLCNNMA_00920	1.25e-240	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HFLCNNMA_00921	4.84e-102	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
HFLCNNMA_00922	8.07e-126	-	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HFLCNNMA_00923	1.16e-184	-	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
HFLCNNMA_00926	1.61e-36	-	-	-	-	-	-	-	-
HFLCNNMA_00927	1.11e-25	-	-	-	L	-	-	-	transposase and inactivated derivatives, IS30 family
HFLCNNMA_00929	1.12e-140	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HFLCNNMA_00930	4.49e-278	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HFLCNNMA_00931	1.1e-181	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HFLCNNMA_00932	3.49e-219	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HFLCNNMA_00933	3.15e-278	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HFLCNNMA_00934	1.29e-114	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HFLCNNMA_00935	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HFLCNNMA_00936	2.72e-237	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HFLCNNMA_00937	5e-57	celA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	beta-glucosidase activity
HFLCNNMA_00938	3.25e-48	pbg4	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HFLCNNMA_00939	7.44e-258	-	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HFLCNNMA_00940	1.69e-256	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HFLCNNMA_00941	1.49e-254	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HFLCNNMA_00942	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HFLCNNMA_00943	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
HFLCNNMA_00944	2.59e-227	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
HFLCNNMA_00945	7.11e-173	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
HFLCNNMA_00946	9.98e-215	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HFLCNNMA_00947	4.68e-99	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HFLCNNMA_00948	1.46e-128	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HFLCNNMA_00949	3.92e-219	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
HFLCNNMA_00950	4.83e-30	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
HFLCNNMA_00951	3.99e-197	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HFLCNNMA_00953	3.6e-209	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HFLCNNMA_00955	7.78e-11	secY2	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	SecY translocase
HFLCNNMA_00956	1.04e-288	aspC	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HFLCNNMA_00957	1.28e-184	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HFLCNNMA_00958	9.27e-96	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HFLCNNMA_00961	1.13e-223	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
HFLCNNMA_00962	1.58e-314	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HFLCNNMA_00963	7.14e-117	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HFLCNNMA_00964	1.65e-210	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Phage integrase, N-terminal SAM-like domain
HFLCNNMA_00965	3.79e-316	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HFLCNNMA_00966	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HFLCNNMA_00967	8.75e-198	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
HFLCNNMA_00968	9.33e-177	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HFLCNNMA_00969	4.39e-210	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HFLCNNMA_00970	9.85e-49	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
HFLCNNMA_00971	5.28e-200	degV3	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
HFLCNNMA_00972	1.14e-150	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
HFLCNNMA_00973	1.02e-280	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HFLCNNMA_00974	5.15e-216	XK27_10395	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HFLCNNMA_00978	4.06e-215	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HFLCNNMA_00979	1.39e-180	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HFLCNNMA_00980	0.0	yfiB1	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HFLCNNMA_00981	1.79e-212	-	-	-	K	-	-	-	LysR substrate binding domain
HFLCNNMA_00982	6.72e-204	-	-	-	-	-	-	-	-
HFLCNNMA_00983	1.52e-129	-	-	-	I	-	-	-	PAP2 superfamily
HFLCNNMA_00984	1.06e-193	-	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
HFLCNNMA_00985	9.3e-310	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HFLCNNMA_00986	9.52e-72	-	-	-	S	-	-	-	Protein of unknown function (DUF2752)
HFLCNNMA_00987	4.04e-222	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF898)
HFLCNNMA_00988	5.93e-135	-	-	-	S	-	-	-	Protein of unknown function (DUF4230)
HFLCNNMA_00989	1.97e-173	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HFLCNNMA_00990	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HFLCNNMA_00991	4.37e-205	lysR5	-	-	K	-	-	-	LysR substrate binding domain
HFLCNNMA_00992	0.0	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
HFLCNNMA_00993	3.67e-147	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HFLCNNMA_00994	4.84e-242	-	-	-	S	-	-	-	AI-2E family transporter
HFLCNNMA_00995	1.39e-257	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
HFLCNNMA_00996	3.83e-200	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
HFLCNNMA_00997	5.47e-66	-	-	-	K	-	-	-	DNA-binding transcription factor activity
HFLCNNMA_00998	2.82e-122	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HFLCNNMA_00999	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
HFLCNNMA_01000	2.47e-156	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
HFLCNNMA_01001	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HFLCNNMA_01002	3.9e-235	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HFLCNNMA_01003	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HFLCNNMA_01004	1.04e-109	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HFLCNNMA_01005	3.09e-244	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HFLCNNMA_01006	6.61e-228	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HFLCNNMA_01007	1.18e-128	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HFLCNNMA_01008	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HFLCNNMA_01009	2.49e-114	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HFLCNNMA_01010	5.16e-218	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HFLCNNMA_01011	5.94e-271	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HFLCNNMA_01012	1.35e-51	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Bacterial transferase hexapeptide (six repeats)
HFLCNNMA_01013	1.31e-213	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HFLCNNMA_01014	2.57e-78	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HFLCNNMA_01015	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HFLCNNMA_01016	1.02e-56	ylxQ	-	-	J	-	-	-	ribosomal protein
HFLCNNMA_01017	1.03e-57	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
HFLCNNMA_01018	1.58e-263	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HFLCNNMA_01019	1.01e-109	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
HFLCNNMA_01020	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HFLCNNMA_01021	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HFLCNNMA_01022	6.52e-289	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
HFLCNNMA_01023	1.97e-187	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
HFLCNNMA_01024	3.99e-176	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HFLCNNMA_01025	2.75e-118	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HFLCNNMA_01026	5.02e-169	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HFLCNNMA_01027	3.29e-236	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HFLCNNMA_01028	1.49e-176	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
HFLCNNMA_01029	1.41e-243	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
HFLCNNMA_01030	1.31e-148	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
HFLCNNMA_01031	5.05e-233	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HFLCNNMA_01032	0.0	-	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HFLCNNMA_01033	2.28e-270	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
HFLCNNMA_01034	1.05e-93	pheB	5.4.99.5	-	S	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the UPF0735 family
HFLCNNMA_01035	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HFLCNNMA_01036	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HFLCNNMA_01037	1.55e-42	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
HFLCNNMA_01038	6.52e-43	ynzC	-	-	S	-	-	-	UPF0291 protein
HFLCNNMA_01039	2.53e-147	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HFLCNNMA_01040	1.68e-192	-	-	-	U	ko:K05340	-	ko00000,ko02000	ribose uptake protein RbsU
HFLCNNMA_01041	2.59e-192	glnH	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HFLCNNMA_01042	1.98e-123	-	-	-	-	-	-	-	-
HFLCNNMA_01043	0.0	-	-	-	L	ko:K03724	-	ko00000,ko01000,ko03400	DEAD DEAH box helicase
HFLCNNMA_01044	1.23e-315	-	-	-	P	-	-	-	P-loop Domain of unknown function (DUF2791)
HFLCNNMA_01045	0.0	-	-	-	S	-	-	-	TerB-C domain
HFLCNNMA_01046	0.0	XK27_00340	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HFLCNNMA_01047	4.71e-74	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HFLCNNMA_01048	0.0	snf	-	-	KL	-	-	-	domain protein
HFLCNNMA_01050	2.41e-178	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
HFLCNNMA_01051	7.02e-119	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HFLCNNMA_01052	3.93e-59	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
HFLCNNMA_01053	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HFLCNNMA_01054	2.27e-71	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HFLCNNMA_01055	5.53e-96	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HFLCNNMA_01056	5.23e-96	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HFLCNNMA_01057	5.31e-22	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HFLCNNMA_01058	4.93e-09	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HFLCNNMA_01059	1.71e-219	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HFLCNNMA_01060	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
HFLCNNMA_01061	2.5e-164	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HFLCNNMA_01062	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HFLCNNMA_01063	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HFLCNNMA_01064	4.18e-208	oppC5	-	-	P	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HFLCNNMA_01065	2.21e-227	oppB	-	-	P	ko:K02033,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HFLCNNMA_01066	3.53e-228	oppF	-	-	P	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HFLCNNMA_01067	3.75e-242	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HFLCNNMA_01068	1.31e-48	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HFLCNNMA_01069	9.78e-232	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HFLCNNMA_01070	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HFLCNNMA_01071	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
HFLCNNMA_01072	1.67e-74	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HFLCNNMA_01073	3.26e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
HFLCNNMA_01074	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
HFLCNNMA_01078	1.76e-162	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
HFLCNNMA_01079	2.01e-212	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HFLCNNMA_01080	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HFLCNNMA_01081	3.83e-178	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
HFLCNNMA_01082	6.32e-310	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HFLCNNMA_01083	3e-223	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HFLCNNMA_01084	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HFLCNNMA_01085	1.28e-45	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HFLCNNMA_01086	2.84e-143	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HFLCNNMA_01087	1.75e-67	-	-	-	-	-	-	-	-
HFLCNNMA_01088	3.94e-45	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	transmembrane transport
HFLCNNMA_01089	6.57e-19	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HFLCNNMA_01090	3.95e-29	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	transmembrane transport
HFLCNNMA_01091	5.85e-12	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	transmembrane transport
HFLCNNMA_01092	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
HFLCNNMA_01093	5.49e-197	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
HFLCNNMA_01094	1.16e-206	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HFLCNNMA_01095	2.38e-43	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HFLCNNMA_01096	0.0	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HFLCNNMA_01097	1.86e-197	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HFLCNNMA_01098	7.64e-88	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HFLCNNMA_01099	6.3e-95	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
HFLCNNMA_01100	8.59e-133	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HFLCNNMA_01101	5.66e-257	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HFLCNNMA_01102	3.79e-64	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
HFLCNNMA_01103	5.61e-65	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
HFLCNNMA_01104	9.71e-68	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
HFLCNNMA_01105	1.1e-119	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
HFLCNNMA_01106	1.57e-68	livF	-	-	E	ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
HFLCNNMA_01107	1.13e-308	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
HFLCNNMA_01108	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
HFLCNNMA_01109	1.17e-141	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HFLCNNMA_01110	9.71e-253	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
HFLCNNMA_01111	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HFLCNNMA_01112	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HFLCNNMA_01113	1.98e-162	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HFLCNNMA_01114	8.7e-52	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HFLCNNMA_01115	5.04e-173	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
HFLCNNMA_01116	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HFLCNNMA_01117	1.94e-270	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HFLCNNMA_01118	1.42e-107	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HFLCNNMA_01119	1.66e-55	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2087)
HFLCNNMA_01120	1.63e-67	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HFLCNNMA_01121	1.61e-126	-	-	-	P	-	-	-	nitrite transmembrane transporter activity
HFLCNNMA_01122	3.91e-106	-	-	-	-	-	-	-	-
HFLCNNMA_01123	2.64e-139	-	-	-	-	-	-	-	-
HFLCNNMA_01124	0.0	-	-	-	S	-	-	-	SH3-like domain
HFLCNNMA_01125	0.0	traI	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HFLCNNMA_01127	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HFLCNNMA_01128	2.22e-312	-	-	-	EGP	-	-	-	Major Facilitator
HFLCNNMA_01130	5.05e-193	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
HFLCNNMA_01131	8.22e-217	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HFLCNNMA_01132	4.74e-71	-	-	-	L	-	-	-	DDE superfamily endonuclease
HFLCNNMA_01133	3.14e-31	-	-	-	L	-	-	-	Transposase
HFLCNNMA_01134	4.43e-294	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
HFLCNNMA_01135	1.55e-260	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
HFLCNNMA_01136	1.92e-238	add	3.5.4.2, 3.5.4.4	-	F	ko:K01488,ko:K02029,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HFLCNNMA_01137	5.59e-75	-	-	-	-	-	-	-	-
HFLCNNMA_01138	1.47e-83	-	-	-	S	-	-	-	Domain of unknown function DUF1828
HFLCNNMA_01139	7.46e-279	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HFLCNNMA_01140	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HFLCNNMA_01141	1.04e-206	ynbB	-	-	P	-	-	-	aluminum resistance
HFLCNNMA_01142	1.87e-218	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HFLCNNMA_01143	8.9e-92	yqhL	-	-	P	-	-	-	Rhodanese-like protein
HFLCNNMA_01144	2.98e-45	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
HFLCNNMA_01145	6.09e-152	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Rhomboid family
HFLCNNMA_01146	2.26e-132	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HFLCNNMA_01147	2.18e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HFLCNNMA_01148	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HFLCNNMA_01149	0.0	-	-	-	S	-	-	-	membrane
HFLCNNMA_01150	2.55e-105	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HFLCNNMA_01151	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HFLCNNMA_01152	4.12e-254	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HFLCNNMA_01153	9.83e-81	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HFLCNNMA_01154	1.27e-173	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HFLCNNMA_01155	5.39e-61	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
HFLCNNMA_01156	4.75e-202	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HFLCNNMA_01157	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HFLCNNMA_01158	1.96e-164	csrR	-	-	K	-	-	-	response regulator
HFLCNNMA_01159	2.09e-130	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
HFLCNNMA_01160	1.68e-273	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
HFLCNNMA_01161	1.46e-77	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HFLCNNMA_01162	6.76e-143	yqeK	-	-	H	-	-	-	Hydrolase, HD family
HFLCNNMA_01163	1.58e-153	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HFLCNNMA_01164	1.16e-270	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
HFLCNNMA_01165	2.91e-74	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HFLCNNMA_01166	1.37e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
HFLCNNMA_01167	3.99e-112	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HFLCNNMA_01168	0.0	-	-	-	L	-	-	-	Putative transposase DNA-binding domain
HFLCNNMA_01169	2.29e-145	-	-	-	L	-	-	-	Resolvase, N terminal domain
HFLCNNMA_01170	0.0	-	-	-	S	ko:K06921	-	ko00000	Archaea bacterial proteins of unknown function
HFLCNNMA_01171	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HFLCNNMA_01172	4.07e-217	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
HFLCNNMA_01173	5.47e-314	dnaB2	-	-	L	ko:K03346	-	ko00000,ko03032	Replication initiation and membrane attachment
HFLCNNMA_01174	1.57e-107	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HFLCNNMA_01175	1.03e-131	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HFLCNNMA_01176	1.03e-202	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HFLCNNMA_01177	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HFLCNNMA_01178	9.6e-50	-	-	-	P	-	-	-	nitrite transmembrane transporter activity
HFLCNNMA_01179	7.87e-71	-	-	-	EGP	-	-	-	Major Facilitator
HFLCNNMA_01180	2.8e-19	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HFLCNNMA_01181	1.67e-27	-	-	-	K	-	-	-	Transcriptional regulator
HFLCNNMA_01182	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
HFLCNNMA_01183	6.93e-154	XK27_10290	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HFLCNNMA_01184	9.52e-72	ytpP	-	-	CO	-	-	-	Thioredoxin
HFLCNNMA_01185	1.64e-158	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HFLCNNMA_01186	1.28e-274	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HFLCNNMA_01187	3.02e-176	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HFLCNNMA_01188	5.82e-105	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
HFLCNNMA_01189	1.4e-71	-	-	-	-	-	-	-	-
HFLCNNMA_01190	1.17e-217	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HFLCNNMA_01191	2.5e-173	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HFLCNNMA_01192	9.14e-146	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HFLCNNMA_01193	8.28e-199	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HFLCNNMA_01194	5.07e-64	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HFLCNNMA_01195	1.81e-86	aroK	1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4	-	F	ko:K00014,ko:K00891,ko:K03785,ko:K03786,ko:K13829,ko:K15546	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko03000	shikimate kinase activity
HFLCNNMA_01196	1.28e-229	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
HFLCNNMA_01197	0.0	yhaN	-	-	L	-	-	-	AAA domain
HFLCNNMA_01198	8.89e-289	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
HFLCNNMA_01199	3.16e-73	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
HFLCNNMA_01200	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HFLCNNMA_01201	7.86e-207	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
HFLCNNMA_01202	9.99e-216	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
HFLCNNMA_01203	2.17e-122	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
HFLCNNMA_01204	6.37e-76	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
HFLCNNMA_01205	3.25e-79	-	-	-	-	-	-	-	-
HFLCNNMA_01206	2.63e-99	-	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
HFLCNNMA_01208	0.0	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
HFLCNNMA_01209	4.69e-202	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HFLCNNMA_01210	7.15e-295	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HFLCNNMA_01212	9.36e-173	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HFLCNNMA_01213	1.38e-183	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HFLCNNMA_01214	2.65e-228	-	-	-	-	-	-	-	-
HFLCNNMA_01215	4.88e-88	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
HFLCNNMA_01216	9.45e-67	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
HFLCNNMA_01217	2e-202	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
HFLCNNMA_01218	1.45e-70	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
HFLCNNMA_01219	2.03e-73	ppsA	2.7.9.2	-	G	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the PEP-utilizing enzyme family
HFLCNNMA_01220	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HFLCNNMA_01221	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
HFLCNNMA_01222	3.8e-252	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HFLCNNMA_01223	8.07e-155	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
HFLCNNMA_01224	0.0	bmr3_1	-	-	EGP	ko:K18935	-	ko00000,ko02000	Sugar (and other) transporter
HFLCNNMA_01225	5.44e-277	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HFLCNNMA_01231	4.36e-300	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HFLCNNMA_01232	2.26e-211	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HFLCNNMA_01233	8.7e-190	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HFLCNNMA_01234	4.66e-178	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
HFLCNNMA_01235	1.56e-203	yicL	-	-	EG	-	-	-	EamA-like transporter family
HFLCNNMA_01236	5.27e-64	pinR1	-	-	L	-	-	-	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
HFLCNNMA_01237	7.26e-39	tnp2	-	-	L	-	-	-	PFAM Transposase, IS204 IS1001 IS1096 IS1165
HFLCNNMA_01238	5.95e-239	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HFLCNNMA_01239	1.36e-178	loxD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
HFLCNNMA_01240	1.22e-60	-	-	-	C	-	-	-	FAD linked oxidase domain protein
HFLCNNMA_01241	1.23e-96	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
HFLCNNMA_01242	2.22e-182	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HFLCNNMA_01243	2.13e-116	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HFLCNNMA_01244	6.43e-195	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
HFLCNNMA_01261	2.31e-213	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
HFLCNNMA_01262	4.34e-63	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
HFLCNNMA_01263	4.05e-09	XK27_07210	-	-	S	-	-	-	B3 4 domain
HFLCNNMA_01264	7.68e-265	-	-	-	S	-	-	-	amidohydrolase
HFLCNNMA_01272	2.29e-26	-	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	MafB19-like deaminase
HFLCNNMA_01273	1.23e-36	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HFLCNNMA_01274	3.65e-56	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
HFLCNNMA_01275	2.13e-106	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
HFLCNNMA_01276	3.02e-179	-	-	-	K	-	-	-	LysR family
HFLCNNMA_01277	9.72e-47	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HFLCNNMA_01278	1.3e-205	-	-	-	J	-	-	-	Methyltransferase
HFLCNNMA_01279	2.56e-234	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Aluminium induced protein
HFLCNNMA_01280	3.6e-127	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Aluminium induced protein
HFLCNNMA_01285	7.41e-06	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
HFLCNNMA_01286	5.53e-265	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
HFLCNNMA_01287	3.82e-183	-	-	-	G	-	-	-	polysaccharide deacetylase
HFLCNNMA_01288	3.15e-14	-	-	-	G	-	-	-	polysaccharide deacetylase
HFLCNNMA_01299	3.56e-67	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	COG1053 Succinate dehydrogenase fumarate reductase, flavoprotein subunit
HFLCNNMA_01300	4.54e-86	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	COG1053 Succinate dehydrogenase fumarate reductase, flavoprotein subunit
HFLCNNMA_01301	1.72e-34	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HFLCNNMA_01302	1.28e-26	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HFLCNNMA_01303	2.28e-217	-	-	-	K	-	-	-	LysR substrate binding domain
HFLCNNMA_01304	2.7e-148	-	-	-	K	-	-	-	SIR2-like domain
HFLCNNMA_01305	1.1e-68	-	-	-	L	ko:K07484	-	ko00000	IS66 Orf2 like protein
HFLCNNMA_01306	2.94e-34	-	-	-	-	-	-	-	-
HFLCNNMA_01307	3.01e-264	-	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
HFLCNNMA_01308	5.87e-87	-	-	-	L	-	-	-	DDE superfamily endonuclease
HFLCNNMA_01309	4.43e-220	-	-	-	S	-	-	-	glycosyl transferase family 2
HFLCNNMA_01310	1.59e-82	-	-	-	S	-	-	-	Protein conserved in bacteria
HFLCNNMA_01311	8.43e-240	-	-	-	S	ko:K19419	-	ko00000,ko02000	EpsG family
HFLCNNMA_01312	3.98e-234	-	-	-	S	-	-	-	Glycosyltransferase like family 2
HFLCNNMA_01313	2.51e-84	-	-	-	M	-	-	-	Capsular polysaccharide synthesis protein
HFLCNNMA_01314	2e-105	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
HFLCNNMA_01315	2.8e-240	-	-	-	G	-	-	-	Glycosyl transferases group 1
HFLCNNMA_01316	1.88e-231	-	-	-	M	-	-	-	Glycosyl transferase 4-like
HFLCNNMA_01317	2.93e-157	epsE2	-	-	M	-	-	-	Bacterial sugar transferase
HFLCNNMA_01318	7.21e-191	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
HFLCNNMA_01319	1.3e-147	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
HFLCNNMA_01320	3.19e-156	epsB	-	-	M	-	-	-	biosynthesis protein
HFLCNNMA_01321	1.39e-233	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HFLCNNMA_01322	6.39e-297	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HFLCNNMA_01323	1.76e-162	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
HFLCNNMA_01324	1.81e-159	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
HFLCNNMA_01325	1.4e-164	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
HFLCNNMA_01326	1.01e-104	lytE	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
HFLCNNMA_01327	3.98e-256	idhA	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HFLCNNMA_01328	5.18e-109	lytE	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family
HFLCNNMA_01329	9.03e-126	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase homologues.
HFLCNNMA_01330	2.89e-64	-	-	-	-	-	-	-	-
HFLCNNMA_01331	0.0	-	-	-	S	-	-	-	O-antigen ligase like membrane protein
HFLCNNMA_01332	4.02e-145	-	-	-	-	-	-	-	-
HFLCNNMA_01333	3.69e-107	-	-	-	-	-	-	-	-
HFLCNNMA_01334	8.56e-109	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HFLCNNMA_01335	9.67e-175	-	-	-	S	-	-	-	Putative threonine/serine exporter
HFLCNNMA_01336	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
HFLCNNMA_01338	2.25e-264	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HFLCNNMA_01339	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
HFLCNNMA_01340	4.65e-130	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HFLCNNMA_01341	2.07e-112	-	-	-	KT	-	-	-	response to antibiotic
HFLCNNMA_01342	2.09e-173	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
HFLCNNMA_01343	1.2e-155	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HFLCNNMA_01344	1.01e-185	-	3.1.3.102, 3.1.3.104, 3.1.3.23	-	G	ko:K07757,ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
HFLCNNMA_01345	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
HFLCNNMA_01346	1.41e-211	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HFLCNNMA_01347	7.41e-175	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
HFLCNNMA_01348	3.86e-186	racD	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
HFLCNNMA_01349	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HFLCNNMA_01350	4.19e-283	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
HFLCNNMA_01351	3.03e-159	vanR	-	-	K	-	-	-	response regulator
HFLCNNMA_01352	2.73e-167	ndvA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HFLCNNMA_01353	7.78e-232	ndvA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HFLCNNMA_01354	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HFLCNNMA_01355	4.63e-177	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
HFLCNNMA_01356	6.88e-257	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HFLCNNMA_01357	6.38e-59	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
HFLCNNMA_01358	4.14e-200	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HFLCNNMA_01359	2.37e-176	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
HFLCNNMA_01360	2.19e-184	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HFLCNNMA_01361	3.68e-170	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
HFLCNNMA_01362	7.44e-113	cvpA	-	-	S	-	-	-	Colicin V production protein
HFLCNNMA_01363	4.03e-239	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HFLCNNMA_01364	2.05e-182	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HFLCNNMA_01365	2.48e-124	azr	1.5.1.36	-	S	ko:K22394	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
HFLCNNMA_01366	2.92e-126	azo1	1.5.1.36, 1.7.1.6	-	S	ko:K03206,ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
HFLCNNMA_01367	4.76e-127	-	-	-	K	-	-	-	WHG domain
HFLCNNMA_01368	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HFLCNNMA_01370	3.98e-151	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HFLCNNMA_01371	3.24e-138	-	-	-	-	-	-	-	-
HFLCNNMA_01373	2.04e-168	-	-	-	-	-	-	-	-
HFLCNNMA_01374	2.79e-153	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HFLCNNMA_01375	4.32e-237	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HFLCNNMA_01376	1.03e-111	-	-	-	K	-	-	-	transcriptional regulator (TetR family)
HFLCNNMA_01377	8.05e-106	glcD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
HFLCNNMA_01378	5.02e-22	glcD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
HFLCNNMA_01379	2.06e-179	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
HFLCNNMA_01380	4.7e-150	-	-	-	-	-	-	-	-
HFLCNNMA_01381	2.13e-178	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
HFLCNNMA_01382	4.3e-75	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
HFLCNNMA_01383	8.79e-63	ydgI	-	-	C	-	-	-	Nitroreductase family
HFLCNNMA_01384	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
HFLCNNMA_01385	3.44e-45	lysM	-	-	M	-	-	-	LysM domain
HFLCNNMA_01386	8.61e-223	citI	-	-	K	-	-	-	Putative sugar-binding domain
HFLCNNMA_01387	5.18e-282	-	-	-	M	ko:K08659	-	ko00000,ko01000,ko01002	Peptidase family C69
HFLCNNMA_01389	0.0	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HFLCNNMA_01390	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HFLCNNMA_01392	2.01e-195	-	-	-	-	-	-	-	-
HFLCNNMA_01393	2.18e-117	ymdB	-	-	S	-	-	-	Macro domain protein
HFLCNNMA_01394	4.38e-184	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HFLCNNMA_01395	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
HFLCNNMA_01396	3.08e-126	-	-	-	KLT	-	-	-	serine threonine protein kinase
HFLCNNMA_01397	0.0	-	-	-	KLT	-	-	-	serine threonine protein kinase
HFLCNNMA_01398	1.44e-178	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HFLCNNMA_01399	2.07e-231	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HFLCNNMA_01400	5.78e-53	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HFLCNNMA_01401	3.87e-168	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
HFLCNNMA_01402	7.46e-50	-	-	-	-	-	-	-	-
HFLCNNMA_01403	0.0	clpL	-	-	O	ko:K04086	-	ko00000,ko03110	C-terminal, D2-small domain, of ClpB protein
HFLCNNMA_01404	2.04e-77	-	-	-	T	-	-	-	diguanylate cyclase
HFLCNNMA_01405	1.95e-192	-	-	-	L	-	-	-	DDE superfamily endonuclease
HFLCNNMA_01406	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HFLCNNMA_01407	4.73e-266	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HFLCNNMA_01408	4.3e-315	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HFLCNNMA_01409	3.29e-233	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HFLCNNMA_01410	2.49e-123	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HFLCNNMA_01411	3.74e-213	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HFLCNNMA_01418	3.25e-35	-	-	-	L	-	-	-	Transposase
HFLCNNMA_01420	1.46e-236	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
HFLCNNMA_01421	5.45e-153	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
HFLCNNMA_01422	4.03e-137	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
HFLCNNMA_01423	5.46e-185	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HFLCNNMA_01424	5.27e-112	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
HFLCNNMA_01425	0.0	sasH	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01081,ko:K01119,ko:K07004,ko:K08693,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HFLCNNMA_01426	2.89e-77	-	-	-	-	-	-	-	-
HFLCNNMA_01427	2.14e-232	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
HFLCNNMA_01428	6.81e-274	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HFLCNNMA_01430	5.67e-34	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HFLCNNMA_01431	4.86e-59	-	-	-	-	-	-	-	-
HFLCNNMA_01432	1.15e-24	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HFLCNNMA_01433	5.67e-196	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
HFLCNNMA_01434	1.78e-147	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HFLCNNMA_01435	1.01e-87	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
HFLCNNMA_01436	3.11e-71	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HFLCNNMA_01437	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HFLCNNMA_01438	1.92e-67	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
HFLCNNMA_01439	6.34e-94	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HFLCNNMA_01440	1.79e-55	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
HFLCNNMA_01441	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HFLCNNMA_01442	1.74e-294	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HFLCNNMA_01443	1.89e-228	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
HFLCNNMA_01444	4.03e-263	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HFLCNNMA_01445	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HFLCNNMA_01446	1.21e-70	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HFLCNNMA_01447	1.02e-236	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HFLCNNMA_01448	4.05e-135	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HFLCNNMA_01449	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HFLCNNMA_01450	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HFLCNNMA_01451	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HFLCNNMA_01452	3.69e-59	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HFLCNNMA_01453	2.3e-158	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HFLCNNMA_01454	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
HFLCNNMA_01455	1.43e-248	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HFLCNNMA_01456	9.08e-124	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
HFLCNNMA_01457	5.82e-163	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
HFLCNNMA_01458	1.56e-115	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
HFLCNNMA_01459	5.22e-114	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
HFLCNNMA_01460	6.15e-183	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
HFLCNNMA_01461	9.14e-204	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HFLCNNMA_01462	2.21e-72	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
HFLCNNMA_01463	5.96e-206	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HFLCNNMA_01464	1.83e-70	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
HFLCNNMA_01465	2.32e-146	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HFLCNNMA_01466	2.21e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
HFLCNNMA_01467	3.6e-139	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HFLCNNMA_01468	1.9e-68	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HFLCNNMA_01469	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HFLCNNMA_01470	2.25e-116	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HFLCNNMA_01471	1.79e-144	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
HFLCNNMA_01472	2.31e-117	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HFLCNNMA_01473	1.47e-96	-	-	-	-	-	-	-	-
HFLCNNMA_01474	8.5e-74	-	-	-	-	-	-	-	-
HFLCNNMA_01475	7.83e-60	-	-	-	-	-	-	-	-
HFLCNNMA_01476	2.25e-16	-	-	-	L	ko:K07483,ko:K07497	-	ko00000	Helix-turn-helix domain
HFLCNNMA_01477	7.54e-264	pbpX1	-	-	V	-	-	-	Beta-lactamase
HFLCNNMA_01478	2.38e-273	pbpX	-	-	V	-	-	-	Beta-lactamase
HFLCNNMA_01479	1.49e-54	-	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HFLCNNMA_01480	1.84e-27	-	5.3.1.6	-	G	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose/Galactose Isomerase
HFLCNNMA_01481	1.22e-15	rpiB2	5.3.1.6	-	G	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose/Galactose Isomerase
HFLCNNMA_01483	1.7e-76	-	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HFLCNNMA_01484	9.22e-18	-	-	-	P	-	-	-	nitric oxide dioxygenase activity
HFLCNNMA_01485	4.29e-185	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HFLCNNMA_01486	7.87e-111	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HFLCNNMA_01487	1.42e-71	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HFLCNNMA_01488	1.35e-108	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HFLCNNMA_01489	2.23e-20	-	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
HFLCNNMA_01490	2.1e-93	-	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
HFLCNNMA_01491	3.39e-94	-	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
HFLCNNMA_01492	5.15e-91	-	-	-	-	-	-	-	-
HFLCNNMA_01493	3.81e-293	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
HFLCNNMA_01494	2.09e-244	-	-	-	S	-	-	-	Glycosyl transferase family 2
HFLCNNMA_01495	4.45e-158	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HFLCNNMA_01496	3.27e-91	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HFLCNNMA_01497	5.63e-131	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HFLCNNMA_01498	3.07e-32	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HFLCNNMA_01499	7.32e-28	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HFLCNNMA_01500	2.07e-38	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HFLCNNMA_01501	8.44e-124	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HFLCNNMA_01502	8.92e-60	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HFLCNNMA_01503	2.32e-150	-	-	-	S	-	-	-	Alpha/beta hydrolase family
HFLCNNMA_01504	3.19e-45	-	-	-	-	-	-	-	-
HFLCNNMA_01505	5.81e-131	-	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factor activity
HFLCNNMA_01506	1.34e-177	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HFLCNNMA_01507	6.26e-101	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HFLCNNMA_01508	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HFLCNNMA_01509	6.07e-137	-	-	-	F	-	-	-	NUDIX domain
HFLCNNMA_01510	3.88e-207	-	-	-	K	-	-	-	LysR substrate binding domain
HFLCNNMA_01511	9.35e-231	-	-	-	S	-	-	-	Conserved hypothetical protein 698
HFLCNNMA_01512	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HFLCNNMA_01514	2.19e-154	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HFLCNNMA_01515	7.32e-79	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
HFLCNNMA_01517	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HFLCNNMA_01518	1.06e-121	-	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HFLCNNMA_01519	1.98e-103	-	-	-	F	-	-	-	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HFLCNNMA_01520	4.75e-180	-	-	-	F	-	-	-	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HFLCNNMA_01521	5.61e-34	-	6.3.4.18, 6.3.5.5	-	F	ko:K01589,ko:K01955,ko:K16181	ko00230,ko00240,ko00250,ko00300,ko01100,ko01110,ko01120,ko01130,map00230,map00240,map00250,map00300,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	5-(carboxyamino)imidazole ribonucleotide synthase activity
HFLCNNMA_01522	8.81e-05	-	6.3.4.18, 6.3.5.5	-	F	ko:K01589,ko:K01955,ko:K16181	ko00230,ko00240,ko00250,ko00300,ko01100,ko01110,ko01120,ko01130,map00230,map00240,map00250,map00300,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	5-(carboxyamino)imidazole ribonucleotide synthase activity
HFLCNNMA_01523	6.7e-205	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HFLCNNMA_01524	6.14e-259	-	-	-	-	-	-	-	-
HFLCNNMA_01525	8.28e-273	-	-	-	EGP	-	-	-	Transmembrane secretion effector
HFLCNNMA_01526	4.78e-272	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HFLCNNMA_01527	1.71e-95	-	-	-	T	-	-	-	diguanylate cyclase
HFLCNNMA_01528	1.29e-23	-	-	-	T	-	-	-	diguanylate cyclase
HFLCNNMA_01530	1.77e-142	-	-	-	T	-	-	-	EAL domain
HFLCNNMA_01531	9.89e-15	-	-	-	T	-	-	-	diguanylate cyclase
HFLCNNMA_01532	7.27e-112	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
HFLCNNMA_01533	0.0	-	1.1.1.1, 1.2.1.10, 1.2.1.87	-	C	ko:K04072,ko:K13922	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Aldehyde dehydrogenase family
HFLCNNMA_01534	2.03e-185	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
HFLCNNMA_01535	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HFLCNNMA_01536	7.66e-130	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
HFLCNNMA_01537	2.84e-205	XK27_10120	-	-	K	-	-	-	S-adenosyl-l-methionine hydroxide adenosyltransferase
HFLCNNMA_01538	0.0	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HFLCNNMA_01539	0.0	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-type transport system involved in multi-copper enzyme maturation permease component
HFLCNNMA_01540	1.27e-217	potA5	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HFLCNNMA_01541	2.53e-80	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
HFLCNNMA_01545	3.62e-38	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
HFLCNNMA_01546	3.87e-74	qorB	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NmrA-like family
HFLCNNMA_01547	6.01e-45	qorB	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	epimerase
HFLCNNMA_01548	1.89e-95	ywnA	-	-	K	-	-	-	Transcriptional regulator
HFLCNNMA_01549	1.33e-110	-	-	-	S	-	-	-	YcxB-like protein
HFLCNNMA_01550	1.07e-129	-	-	-	T	-	-	-	integral membrane protein
HFLCNNMA_01551	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
HFLCNNMA_01552	2.64e-116	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
HFLCNNMA_01553	3.56e-196	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
HFLCNNMA_01554	1.01e-33	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HFLCNNMA_01555	2.85e-15	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HFLCNNMA_01556	0.0	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HFLCNNMA_01558	5.36e-171	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
HFLCNNMA_01559	1.1e-144	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HFLCNNMA_01561	6.96e-30	-	-	-	-	-	-	-	-
HFLCNNMA_01562	0.0	-	-	-	KLT	-	-	-	Protein kinase domain
HFLCNNMA_01563	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K06147,ko:K11085,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
HFLCNNMA_01564	3.6e-35	-	-	-	-	-	-	-	-
HFLCNNMA_01566	6.68e-244	pltK	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HFLCNNMA_01567	2.67e-178	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HFLCNNMA_01568	5.39e-77	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
HFLCNNMA_01569	3.11e-152	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
HFLCNNMA_01570	2.35e-213	-	-	-	V	-	-	-	ABC transporter transmembrane region
HFLCNNMA_01571	3.4e-95	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HFLCNNMA_01573	3.24e-157	-	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
HFLCNNMA_01575	4.46e-90	-	-	-	-	-	-	-	-
HFLCNNMA_01576	0.0	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
HFLCNNMA_01577	4.21e-288	-	-	-	S	-	-	-	Protein of unknown function (DUF2974)
HFLCNNMA_01578	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HFLCNNMA_01579	1.11e-96	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HFLCNNMA_01580	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
HFLCNNMA_01581	1.61e-48	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HFLCNNMA_01582	1.79e-126	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HFLCNNMA_01583	1e-62	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
HFLCNNMA_01584	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HFLCNNMA_01585	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HFLCNNMA_01586	2.02e-268	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HFLCNNMA_01587	2.22e-50	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
HFLCNNMA_01588	9.76e-257	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HFLCNNMA_01589	1.7e-313	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HFLCNNMA_01590	6.59e-23	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
HFLCNNMA_01591	1.48e-82	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HFLCNNMA_01592	1.28e-195	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HFLCNNMA_01593	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HFLCNNMA_01594	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HFLCNNMA_01595	0.0	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HFLCNNMA_01596	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HFLCNNMA_01597	1.35e-97	-	-	-	-	-	-	-	-
HFLCNNMA_01598	3.4e-86	-	-	-	-	-	-	-	-
HFLCNNMA_01599	6.76e-180	-	-	-	-	-	-	-	-
HFLCNNMA_01600	1.26e-122	-	-	-	-	-	-	-	-
HFLCNNMA_01601	2.81e-141	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HFLCNNMA_01602	5.48e-135	-	-	-	-	-	-	-	-
HFLCNNMA_01603	1.05e-147	-	-	-	-	-	-	-	-
HFLCNNMA_01604	3.79e-119	-	-	-	-	-	-	-	-
HFLCNNMA_01605	1.51e-91	-	-	-	-	-	-	-	-
HFLCNNMA_01606	2.56e-20	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HFLCNNMA_01607	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HFLCNNMA_01608	1.55e-293	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HFLCNNMA_01609	8.7e-178	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HFLCNNMA_01610	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HFLCNNMA_01611	1.14e-165	dgk2	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
HFLCNNMA_01612	6.66e-159	dak	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
HFLCNNMA_01613	4.44e-51	-	-	-	-	-	-	-	-
HFLCNNMA_01614	4.95e-196	ybfG	-	-	M	-	-	-	peptidoglycan-binding domain-containing protein
HFLCNNMA_01616	3.02e-19	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
HFLCNNMA_01618	2.58e-163	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HFLCNNMA_01619	1.78e-202	-	-	-	S	-	-	-	Aldo/keto reductase family
HFLCNNMA_01620	2.9e-120	-	-	-	EGP	-	-	-	Major Facilitator
HFLCNNMA_01621	1.03e-77	-	-	-	EGP	-	-	-	Major Facilitator
HFLCNNMA_01622	1.36e-09	-	-	-	EGP	-	-	-	Major Facilitator
HFLCNNMA_01623	1.04e-220	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HFLCNNMA_01624	3.73e-263	mglC	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HFLCNNMA_01625	0.0	mglA	3.6.3.17	-	S	ko:K02056,ko:K06400	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
HFLCNNMA_01626	1.82e-254	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein PnrA-like
HFLCNNMA_01627	5.6e-251	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein PnrA-like
HFLCNNMA_01628	3.65e-95	-	-	-	S	-	-	-	Domain of unknown function (DUF4352)
HFLCNNMA_01629	2.43e-240	pkn2	-	-	KLT	-	-	-	Protein tyrosine kinase
HFLCNNMA_01630	1.35e-85	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HFLCNNMA_01632	2.36e-249	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein PnrA-like
HFLCNNMA_01633	8.03e-256	-	-	-	S	-	-	-	DUF218 domain
HFLCNNMA_01634	7.53e-158	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HFLCNNMA_01635	2.79e-257	napA	-	-	P	-	-	-	Sodium/hydrogen exchanger family
HFLCNNMA_01636	0.0	cadA	-	-	P	-	-	-	P-type ATPase
HFLCNNMA_01637	1.04e-110	ykuL	-	-	S	-	-	-	(CBS) domain
HFLCNNMA_01638	2.61e-82	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
HFLCNNMA_01639	1.86e-286	-	-	-	S	-	-	-	Membrane
HFLCNNMA_01640	1.75e-38	-	-	-	-	-	-	-	-
HFLCNNMA_01641	0.000111	-	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
HFLCNNMA_01642	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HFLCNNMA_01643	4.55e-307	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
HFLCNNMA_01644	1.12e-49	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HFLCNNMA_01645	6.34e-314	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HFLCNNMA_01647	4.13e-86	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
HFLCNNMA_01648	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HFLCNNMA_01649	3.58e-148	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HFLCNNMA_01650	1.1e-96	-	-	-	-	-	-	-	-
HFLCNNMA_01654	1.67e-91	-	-	-	E	-	-	-	Methionine synthase
HFLCNNMA_01655	5.95e-302	-	-	-	EK	-	-	-	Aminotransferase, class I
HFLCNNMA_01656	4.21e-213	yvbU	-	-	K	-	-	-	LysR substrate binding domain
HFLCNNMA_01657	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
HFLCNNMA_01658	6.58e-101	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HFLCNNMA_01659	2.34e-283	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HFLCNNMA_01660	1.76e-259	-	-	-	S	ko:K07045	-	ko00000	Amidohydrolase
HFLCNNMA_01661	6.55e-223	gyaR	1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81	-	CH	ko:K00015,ko:K00090	ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HFLCNNMA_01662	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HFLCNNMA_01663	9.49e-76	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HFLCNNMA_01664	1.45e-233	iunH	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	inosine-uridine preferring nucleoside hydrolase
HFLCNNMA_01665	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HFLCNNMA_01666	6.47e-298	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HFLCNNMA_01667	0.0	oatA	-	-	I	-	-	-	Acyltransferase
HFLCNNMA_01668	1.09e-222	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HFLCNNMA_01669	3.49e-176	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
HFLCNNMA_01670	3.88e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
HFLCNNMA_01671	0.0	yfkN	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HFLCNNMA_01672	0.0	-	-	-	L	-	-	-	SNF2 family N-terminal domain
HFLCNNMA_01673	5.63e-45	-	-	-	-	-	-	-	-
HFLCNNMA_01675	1.37e-128	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
HFLCNNMA_01676	2.82e-19	-	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA
HFLCNNMA_01677	6.57e-72	-	-	-	K	ko:K03492	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
HFLCNNMA_01678	5.61e-115	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HFLCNNMA_01679	2.87e-39	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
HFLCNNMA_01680	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
HFLCNNMA_01681	1.62e-229	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HFLCNNMA_01682	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
HFLCNNMA_01683	5.98e-72	ssuB	-	-	P	ko:K02049,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	anion transmembrane transporter activity
HFLCNNMA_01684	1.89e-119	-	-	-	I	-	-	-	Acyltransferase family
HFLCNNMA_01685	4.38e-209	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
HFLCNNMA_01686	1.26e-211	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
HFLCNNMA_01687	2.22e-82	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HFLCNNMA_01688	6.52e-164	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HFLCNNMA_01689	1.77e-135	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HFLCNNMA_01690	4.13e-167	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HFLCNNMA_01691	3.33e-150	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HFLCNNMA_01692	5.23e-06	mltD	-	-	M	ko:K08307	-	ko00000,ko01000,ko01011	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HFLCNNMA_01693	1.22e-139	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
HFLCNNMA_01694	2.51e-279	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
HFLCNNMA_01695	7.74e-314	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HFLCNNMA_01696	5.57e-55	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HFLCNNMA_01697	1.68e-292	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
HFLCNNMA_01698	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
HFLCNNMA_01699	8.59e-221	-	-	-	K	-	-	-	LysR substrate binding domain
HFLCNNMA_01700	1.77e-11	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
HFLCNNMA_01701	4.57e-134	-	-	-	K	ko:K13928	-	ko00000,ko03000	DNA-binding transcription factor activity
HFLCNNMA_01702	2.61e-35	-	-	-	-	-	-	-	-
HFLCNNMA_01704	0.0	-	-	-	I	-	-	-	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HFLCNNMA_01705	5.36e-93	-	-	-	-	-	-	-	-
HFLCNNMA_01707	9.54e-118	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
HFLCNNMA_01708	1.02e-98	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
HFLCNNMA_01710	8.89e-26	-	-	-	-	-	-	-	-
HFLCNNMA_01712	0.0	cas3	-	-	L	ko:K07012	-	ko00000,ko01000,ko02048	CRISPR-associated helicase cas3
HFLCNNMA_01713	0.0	casA	-	-	L	ko:K19123	-	ko00000,ko02048	the current gene model (or a revised gene model) may contain a frame shift
HFLCNNMA_01714	1.41e-142	-	-	-	S	ko:K19046	-	ko00000,ko02048	CRISPR-associated protein Cse2 (CRISPR_cse2)
HFLCNNMA_01715	6.88e-237	casC	-	-	L	ko:K19124	-	ko00000,ko02048	CT1975-like protein
HFLCNNMA_01716	1.1e-168	casD	-	-	S	ko:K19125	-	ko00000,ko02048	CRISPR-associated protein (Cas_Cas5)
HFLCNNMA_01717	1.71e-150	casE	-	-	S	ko:K19126	-	ko00000,ko02048	CRISPR_assoc
HFLCNNMA_01718	2.28e-223	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HFLCNNMA_01719	1.83e-200	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR-associated protein (Cas_Cas2CT1978)
HFLCNNMA_01720	8.48e-145	-	-	-	T	-	-	-	Region found in RelA / SpoT proteins
HFLCNNMA_01721	1.55e-149	dltr	-	-	K	-	-	-	response regulator
HFLCNNMA_01722	2.29e-291	sptS	-	-	T	-	-	-	Histidine kinase
HFLCNNMA_01723	4.76e-248	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
HFLCNNMA_01724	9.4e-275	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
HFLCNNMA_01725	6.16e-282	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
HFLCNNMA_01726	3.13e-308	-	-	-	S	-	-	-	Putative threonine/serine exporter
HFLCNNMA_01727	1.16e-115	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HFLCNNMA_01728	2.28e-222	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
HFLCNNMA_01729	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HFLCNNMA_01730	2.42e-97	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HFLCNNMA_01731	5e-311	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
HFLCNNMA_01732	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HFLCNNMA_01733	6.11e-13	-	-	-	-	-	-	-	-
HFLCNNMA_01734	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
HFLCNNMA_01735	1.75e-234	ydbI	-	-	K	-	-	-	AI-2E family transporter
HFLCNNMA_01736	2.37e-222	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HFLCNNMA_01737	1.31e-44	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HFLCNNMA_01738	5.44e-230	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
HFLCNNMA_01739	1.53e-158	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
HFLCNNMA_01740	3.77e-288	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HFLCNNMA_01741	1.21e-93	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HFLCNNMA_01742	6.26e-101	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HFLCNNMA_01743	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
HFLCNNMA_01744	1.85e-205	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HFLCNNMA_01745	2.12e-177	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
HFLCNNMA_01746	5.2e-163	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
HFLCNNMA_01747	8.75e-160	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HFLCNNMA_01749	1.69e-65	-	-	-	S	-	-	-	Domain of Unknown Function with PDB structure (DUF3862)
HFLCNNMA_01752	6.87e-311	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
HFLCNNMA_01753	1.79e-72	-	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
HFLCNNMA_01755	5.49e-238	manL	2.7.1.191	-	G	ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HFLCNNMA_01756	5.16e-181	manY	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
HFLCNNMA_01757	7.29e-214	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
HFLCNNMA_01758	5.52e-82	-	-	-	S	-	-	-	Domain of unknown function (DUF956)
HFLCNNMA_01759	5.33e-08	-	-	-	-	-	-	-	-
HFLCNNMA_01760	4.66e-312	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HFLCNNMA_01761	1.16e-207	-	3.4.14.13	-	M	ko:K20742	-	ko00000,ko01000,ko01002	NlpC/P60 family
HFLCNNMA_01764	1.36e-242	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HFLCNNMA_01765	1.42e-119	-	-	-	L	-	-	-	Helicase conserved C-terminal domain
HFLCNNMA_01766	0.0	-	-	-	L	-	-	-	Helicase conserved C-terminal domain
HFLCNNMA_01767	3.39e-63	-	-	-	-	-	-	-	-
HFLCNNMA_01770	2.42e-282	oxlT	-	-	P	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
HFLCNNMA_01771	1.51e-25	malS	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Glycogen debranching enzyme, glucanotransferase domain
HFLCNNMA_01772	3.24e-251	malS	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Glycogen debranching enzyme, glucanotransferase domain
HFLCNNMA_01774	1.23e-255	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
HFLCNNMA_01775	2.57e-262	-	-	-	G	-	-	-	Major Facilitator Superfamily
HFLCNNMA_01776	3.21e-48	-	-	-	L	ko:K07497	-	ko00000	COG2963 Transposase and inactivated derivatives
HFLCNNMA_01777	7.9e-259	-	-	-	G	-	-	-	Major Facilitator Superfamily
HFLCNNMA_01778	2.78e-142	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HFLCNNMA_01779	0.0	-	-	-	E	-	-	-	Amino acid permease
HFLCNNMA_01780	0.0	speA	4.1.1.17, 4.1.1.18, 4.1.1.19	-	E	ko:K01581,ko:K01582,ko:K01585	ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Orn/Lys/Arg decarboxylase, C-terminal domain
HFLCNNMA_01781	5.94e-99	malZ	3.2.1.20, 3.2.1.41	CBM48,GH13,GH31	G	ko:K01187,ko:K01200	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HFLCNNMA_01782	7.54e-82	malZ	3.2.1.20, 3.2.1.41	CBM48,GH13,GH31	G	ko:K01187,ko:K01200	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HFLCNNMA_01783	8.23e-94	malZ	3.2.1.20, 3.2.1.41	CBM48,GH13,GH31	G	ko:K01187,ko:K01200	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HFLCNNMA_01784	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HFLCNNMA_01785	9.39e-256	-	2.7.1.11, 2.7.1.90	-	F	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HFLCNNMA_01786	5.2e-83	-	2.7.1.211	-	G	ko:K02755,ko:K02756,ko:K02757,ko:K02777,ko:K02808,ko:K02809,ko:K02810	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HFLCNNMA_01787	3.55e-199	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
HFLCNNMA_01788	2.46e-171	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
HFLCNNMA_01789	3.18e-34	-	-	-	-	-	-	-	-
HFLCNNMA_01790	5.31e-136	yiiE	-	-	S	-	-	-	Protein of unknown function (DUF1211)
HFLCNNMA_01791	6.92e-128	-	2.3.1.128	-	K	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HFLCNNMA_01795	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
HFLCNNMA_01796	4.34e-202	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HFLCNNMA_01801	1.64e-117	-	-	-	M	-	-	-	LysM domain protein
HFLCNNMA_01802	1.71e-188	-	-	-	D	-	-	-	nuclear chromosome segregation
HFLCNNMA_01803	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Fumarase C C-terminus
HFLCNNMA_01804	3.01e-11	-	-	-	K	ko:K02530	-	ko00000,ko03000	DeoR C terminal sensor domain
HFLCNNMA_01805	2.07e-214	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HFLCNNMA_01806	6.17e-62	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HFLCNNMA_01807	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
HFLCNNMA_01808	9.02e-177	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HFLCNNMA_01809	1.09e-128	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase
HFLCNNMA_01810	8.28e-251	ykfB	5.1.1.20	-	M	ko:K19802	-	ko00000,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
HFLCNNMA_01811	1.58e-122	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HFLCNNMA_01812	2.77e-140	thiJ	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
HFLCNNMA_01813	1.09e-159	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HFLCNNMA_01814	5.92e-165	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
HFLCNNMA_01815	2.88e-39	-	-	-	-	-	-	-	-
HFLCNNMA_01816	1.18e-38	-	-	-	-	-	-	-	-
HFLCNNMA_01817	3.41e-159	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HFLCNNMA_01818	8.76e-104	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HFLCNNMA_01819	4.68e-234	-	-	-	S	-	-	-	AAA domain
HFLCNNMA_01820	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HFLCNNMA_01821	7.39e-65	-	-	-	-	-	-	-	-
HFLCNNMA_01822	1.09e-128	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
HFLCNNMA_01823	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HFLCNNMA_01824	4.02e-237	-	-	-	M	-	-	-	Glycosyl transferase family 8
HFLCNNMA_01825	2.17e-193	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HFLCNNMA_01826	1.15e-71	-	-	-	C	-	-	-	FAD binding domain
HFLCNNMA_01827	7.85e-119	-	-	-	C	-	-	-	FAD binding domain
HFLCNNMA_01828	6.74e-07	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	domain protein
HFLCNNMA_01829	5.44e-14	-	-	-	K	-	-	-	LysR substrate binding domain
HFLCNNMA_01830	2.43e-52	-	-	-	K	-	-	-	LysR substrate binding domain
HFLCNNMA_01831	2.36e-283	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
HFLCNNMA_01832	4.75e-215	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HFLCNNMA_01833	9.19e-98	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
HFLCNNMA_01834	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
HFLCNNMA_01835	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
HFLCNNMA_01836	8.88e-103	-	-	-	GM	-	-	-	NmrA-like family
HFLCNNMA_01837	4.6e-119	-	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
HFLCNNMA_01838	1.73e-97	-	-	-	S	ko:K07126	-	ko00000	Sel1-like repeats.
HFLCNNMA_01839	3.6e-266	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
HFLCNNMA_01840	2.97e-266	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
HFLCNNMA_01841	2.49e-255	xerS	-	-	L	ko:K03733	-	ko00000,ko03036	Belongs to the 'phage' integrase family
HFLCNNMA_01842	1.93e-259	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HFLCNNMA_01843	2.95e-124	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HFLCNNMA_01844	3.3e-115	yfhC	-	-	C	-	-	-	Nitroreductase family
HFLCNNMA_01845	3.62e-41	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HFLCNNMA_01846	3.88e-147	pgm1	-	-	G	-	-	-	phosphoglycerate mutase
HFLCNNMA_01847	8.46e-71	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HFLCNNMA_01848	3.21e-144	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HFLCNNMA_01849	3.14e-110	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HFLCNNMA_01850	1.59e-154	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HFLCNNMA_01851	7.87e-213	-	-	-	EG	-	-	-	EamA-like transporter family
HFLCNNMA_01852	8.74e-239	-	-	-	-	-	-	-	-
HFLCNNMA_01853	1.7e-202	-	-	-	S	-	-	-	EDD domain protein, DegV family
HFLCNNMA_01854	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
HFLCNNMA_01855	1.39e-313	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
HFLCNNMA_01856	4.02e-58	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
HFLCNNMA_01857	0.0	carB1	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HFLCNNMA_01858	1.88e-251	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HFLCNNMA_01859	1.95e-218	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HFLCNNMA_01860	1.3e-99	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HFLCNNMA_01861	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
HFLCNNMA_01862	1.28e-77	-	-	-	-	-	-	-	-
HFLCNNMA_01863	2.42e-238	XK27_01810	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HFLCNNMA_01864	2.29e-275	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
HFLCNNMA_01865	5.35e-85	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HFLCNNMA_01866	2.12e-136	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
HFLCNNMA_01867	6.44e-152	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HFLCNNMA_01868	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
HFLCNNMA_01869	0.0	yuxL	3.4.19.1	-	E	ko:K01303	-	ko00000,ko01000,ko01002	Prolyl oligopeptidase family
HFLCNNMA_01870	5.32e-242	-	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HFLCNNMA_01871	3.26e-78	-	-	-	I	-	-	-	acetylesterase activity
HFLCNNMA_01872	5.21e-91	-	-	-	I	-	-	-	Psort location Cytoplasmic, score
HFLCNNMA_01873	4.33e-192	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HFLCNNMA_01874	4.71e-149	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HFLCNNMA_01875	1.24e-147	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
HFLCNNMA_01876	1.46e-39	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
HFLCNNMA_01878	4.73e-65	-	-	-	S	-	-	-	SLAP domain
HFLCNNMA_01879	1.96e-136	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HFLCNNMA_01882	2.7e-243	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HFLCNNMA_01883	1.74e-107	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HFLCNNMA_01885	5.11e-18	-	-	-	C	-	-	-	Pyridoxamine 5'-phosphate oxidase
HFLCNNMA_01886	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HFLCNNMA_01887	2.02e-168	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HFLCNNMA_01888	2.88e-92	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Low molecular weight phosphotyrosine protein phosphatase
HFLCNNMA_01889	2.73e-98	-	-	-	-	-	-	-	-
HFLCNNMA_01890	2.44e-66	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HFLCNNMA_01891	1.09e-120	cylB	-	-	U	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
HFLCNNMA_01892	1.74e-136	-	-	-	L	-	-	-	Integrase
HFLCNNMA_01893	6.4e-93	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
HFLCNNMA_01894	1.01e-95	-	-	-	K	-	-	-	3.5.2 Transcription regulation
HFLCNNMA_01895	1.22e-275	-	-	-	V	-	-	-	MATE efflux family protein
HFLCNNMA_01896	1.38e-49	-	-	-	T	-	-	-	diguanylate cyclase activity
HFLCNNMA_01897	3.15e-245	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HFLCNNMA_01898	0.0	carB	-	-	F	-	-	-	Psort location Cytoplasmic, score 8.87
HFLCNNMA_01899	3.38e-62	-	-	-	V	ko:K06147	-	ko00000,ko02000	(ABC) transporter
HFLCNNMA_01900	3.75e-92	ybaJ	-	-	Q	-	-	-	Hypothetical methyltransferase
HFLCNNMA_01901	7.57e-10	-	-	-	Q	-	-	-	Methyltransferase domain
HFLCNNMA_01902	3.6e-280	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HFLCNNMA_01903	1.09e-61	-	-	-	E	-	-	-	transmembrane transport
HFLCNNMA_01904	9.35e-161	WQ51_05710	-	-	S	-	-	-	Mitochondrial biogenesis AIM24
HFLCNNMA_01905	3.33e-97	-	-	-	K	-	-	-	Transcriptional regulator
HFLCNNMA_01906	1.12e-58	-	-	-	-	-	-	-	-
HFLCNNMA_01910	0.0	-	-	-	D	-	-	-	Putative exonuclease SbcCD, C subunit
HFLCNNMA_01911	1.73e-76	-	-	-	-	-	-	-	-
HFLCNNMA_01912	2.87e-119	-	-	-	S	ko:K06889	-	ko00000	Hydrolases of the alpha beta superfamily
HFLCNNMA_01913	1.63e-146	ylbE	-	-	GM	-	-	-	NAD(P)H-binding
HFLCNNMA_01914	6.38e-61	-	-	-	V	ko:K06147	-	ko00000,ko02000	(ABC) transporter
HFLCNNMA_01915	1.07e-213	-	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
HFLCNNMA_01916	2.67e-101	-	-	-	V	ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score
HFLCNNMA_01917	1.13e-223	gyaR	1.1.1.26, 1.1.1.399, 1.1.1.95	-	CH	ko:K00015,ko:K00058	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HFLCNNMA_01918	8.42e-102	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
HFLCNNMA_01919	0.0	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HFLCNNMA_01920	0.0	XK27_09605	-	-	V	ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter transmembrane region
HFLCNNMA_01921	4.63e-68	XK27_05625	-	-	P	-	-	-	Rhodanese Homology Domain
HFLCNNMA_01922	5.09e-89	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA-DNA hybrid ribonuclease activity
HFLCNNMA_01923	1.69e-145	-	-	-	L	-	-	-	Resolvase, N-terminal
HFLCNNMA_01924	4.63e-98	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HFLCNNMA_01926	9.05e-55	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
HFLCNNMA_01927	2.9e-167	-	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD-hyrolase-like