Read a JSON File

ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
IHHMCIAP_00001	5.7e-148	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
IHHMCIAP_00002	5.37e-241	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
IHHMCIAP_00003	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
IHHMCIAP_00004	1.03e-150	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IHHMCIAP_00005	1.98e-237	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IHHMCIAP_00006	4.71e-169	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
IHHMCIAP_00007	0.0	aha1	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
IHHMCIAP_00008	9.2e-46	aha1	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
IHHMCIAP_00009	2.2e-115	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IHHMCIAP_00010	2.34e-242	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IHHMCIAP_00011	2.93e-158	-	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
IHHMCIAP_00012	3.58e-85	-	-	-	-	-	-	-	-
IHHMCIAP_00013	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
IHHMCIAP_00015	1.46e-162	pnb	-	-	C	-	-	-	nitroreductase
IHHMCIAP_00016	2.77e-08	-	-	-	-	-	-	-	-
IHHMCIAP_00017	9.69e-239	-	-	-	I	-	-	-	Protein of unknown function (DUF2974)
IHHMCIAP_00018	2.86e-64	-	-	-	S	-	-	-	Protein of unknown function (DUF2974)
IHHMCIAP_00019	3.33e-140	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
IHHMCIAP_00020	1.83e-296	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IHHMCIAP_00021	1.6e-276	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
IHHMCIAP_00022	7.85e-285	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IHHMCIAP_00023	3.14e-189	-	-	-	-	-	-	-	-
IHHMCIAP_00024	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IHHMCIAP_00025	1.01e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IHHMCIAP_00026	7.29e-45	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
IHHMCIAP_00027	6.37e-232	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
IHHMCIAP_00028	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
IHHMCIAP_00029	7.89e-119	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
IHHMCIAP_00030	1.26e-242	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
IHHMCIAP_00031	1.04e-107	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IHHMCIAP_00032	5.62e-126	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
IHHMCIAP_00033	1.31e-70	ylbG	-	-	S	-	-	-	UPF0298 protein
IHHMCIAP_00034	1.37e-271	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
IHHMCIAP_00035	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
IHHMCIAP_00036	8.33e-133	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IHHMCIAP_00037	3.04e-48	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
IHHMCIAP_00038	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IHHMCIAP_00039	0.0	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
IHHMCIAP_00040	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
IHHMCIAP_00041	8.69e-149	-	-	-	S	-	-	-	repeat protein
IHHMCIAP_00042	7.5e-160	pgm	-	-	G	-	-	-	Phosphoglycerate mutase family
IHHMCIAP_00043	3.28e-280	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
IHHMCIAP_00044	2.45e-75	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
IHHMCIAP_00045	3.66e-274	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
IHHMCIAP_00046	1.56e-163	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IHHMCIAP_00047	3.72e-36	-	-	-	-	-	-	-	-
IHHMCIAP_00048	3.66e-132	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
IHHMCIAP_00049	3.24e-44	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
IHHMCIAP_00050	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IHHMCIAP_00051	1.14e-186	ylmH	-	-	S	-	-	-	S4 domain protein
IHHMCIAP_00052	7.21e-62	yggT	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
IHHMCIAP_00053	3.21e-99	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
IHHMCIAP_00054	4.44e-308	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IHHMCIAP_00055	0.0	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
IHHMCIAP_00056	3.01e-190	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
IHHMCIAP_00057	2.35e-266	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IHHMCIAP_00058	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IHHMCIAP_00059	1.09e-227	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IHHMCIAP_00060	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
IHHMCIAP_00061	1.14e-71	ftsL	-	-	D	-	-	-	Cell division protein FtsL
IHHMCIAP_00062	2.66e-221	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
IHHMCIAP_00063	4.45e-99	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
IHHMCIAP_00064	2.49e-73	-	-	-	S	-	-	-	Protein of unknown function (DUF3397)
IHHMCIAP_00066	1.62e-123	mreD	-	-	-	ko:K03571	-	ko00000,ko03036	-
IHHMCIAP_00067	2.17e-175	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
IHHMCIAP_00068	9.63e-225	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
IHHMCIAP_00069	5.69e-91	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
IHHMCIAP_00070	1.15e-162	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
IHHMCIAP_00071	2.5e-296	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
IHHMCIAP_00072	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
IHHMCIAP_00073	2.38e-167	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
IHHMCIAP_00074	8.93e-291	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IHHMCIAP_00075	6.59e-276	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
IHHMCIAP_00076	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
IHHMCIAP_00077	3.59e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IHHMCIAP_00078	4e-105	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
IHHMCIAP_00079	1.55e-308	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
IHHMCIAP_00080	5.05e-57	-	-	-	-	-	-	-	-
IHHMCIAP_00081	5.41e-52	uspA	-	-	T	-	-	-	universal stress protein
IHHMCIAP_00082	1.19e-279	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
IHHMCIAP_00083	6.23e-47	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
IHHMCIAP_00084	8.88e-64	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
IHHMCIAP_00085	1.13e-225	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
IHHMCIAP_00086	7.57e-44	-	-	-	S	-	-	-	Protein of unknown function (DUF1146)
IHHMCIAP_00087	3.63e-95	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
IHHMCIAP_00088	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IHHMCIAP_00089	1.66e-218	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IHHMCIAP_00090	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IHHMCIAP_00091	2.9e-122	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IHHMCIAP_00092	6.38e-102	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IHHMCIAP_00093	1.68e-37	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IHHMCIAP_00094	9.32e-164	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
IHHMCIAP_00095	2.61e-146	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IHHMCIAP_00096	8.81e-240	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
IHHMCIAP_00097	3.44e-200	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
IHHMCIAP_00098	2.77e-249	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IHHMCIAP_00099	1.08e-145	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
IHHMCIAP_00100	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Mur ligase, middle domain
IHHMCIAP_00101	3.69e-45	-	-	-	-	-	-	-	-
IHHMCIAP_00102	2.97e-244	ampC	-	-	V	-	-	-	Beta-lactamase
IHHMCIAP_00105	1.29e-103	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
IHHMCIAP_00106	1.91e-107	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
IHHMCIAP_00107	2.19e-111	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
IHHMCIAP_00108	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
IHHMCIAP_00109	4.43e-138	vanZ	-	-	V	-	-	-	VanZ like family
IHHMCIAP_00110	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
IHHMCIAP_00111	0.0	yclK	-	-	T	-	-	-	Histidine kinase
IHHMCIAP_00112	7.74e-173	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
IHHMCIAP_00115	4.9e-283	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IHHMCIAP_00116	2.51e-235	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
IHHMCIAP_00119	2.11e-98	-	-	-	-	ko:K02246	-	ko00000,ko00002,ko02044	-
IHHMCIAP_00120	2.72e-67	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
IHHMCIAP_00121	5.81e-209	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
IHHMCIAP_00122	2.81e-232	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
IHHMCIAP_00123	1.01e-169	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
IHHMCIAP_00124	2.32e-121	-	-	-	S	-	-	-	VanZ like family
IHHMCIAP_00125	1.93e-208	psaA	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
IHHMCIAP_00126	9.34e-203	-	-	-	S	-	-	-	Phospholipase, patatin family
IHHMCIAP_00127	8.44e-133	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IHHMCIAP_00128	0.0	-	-	-	E	-	-	-	Amino acid permease
IHHMCIAP_00129	1.54e-87	-	-	-	GM	-	-	-	epimerase
IHHMCIAP_00130	5.29e-109	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IHHMCIAP_00131	4.9e-86	-	-	-	-	-	-	-	-
IHHMCIAP_00133	4.47e-234	-	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
IHHMCIAP_00134	1.18e-57	-	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
IHHMCIAP_00135	1.06e-231	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
IHHMCIAP_00136	1.43e-153	-	-	-	T	-	-	-	diguanylate cyclase activity
IHHMCIAP_00137	4.18e-95	-	-	-	-	-	-	-	-
IHHMCIAP_00138	2.04e-79	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IHHMCIAP_00139	1.1e-85	crcB1	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IHHMCIAP_00140	0.0	copA	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
IHHMCIAP_00141	6e-84	-	-	-	S	-	-	-	Cupredoxin-like domain
IHHMCIAP_00142	3.22e-103	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
IHHMCIAP_00143	6.52e-75	-	-	-	V	-	-	-	peptidase activity
IHHMCIAP_00144	1.1e-191	-	-	-	S	-	-	-	hydrolase
IHHMCIAP_00145	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IHHMCIAP_00146	6.44e-214	ybbR	-	-	S	-	-	-	YbbR-like protein
IHHMCIAP_00147	1.1e-191	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IHHMCIAP_00148	3.44e-263	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IHHMCIAP_00149	2.96e-174	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IHHMCIAP_00150	9.32e-184	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IHHMCIAP_00151	6.4e-260	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
IHHMCIAP_00152	1.25e-206	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
IHHMCIAP_00153	9.43e-127	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
IHHMCIAP_00154	1.13e-112	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
IHHMCIAP_00155	3.29e-234	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
IHHMCIAP_00156	7.22e-171	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IHHMCIAP_00157	1.91e-204	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
IHHMCIAP_00158	3.79e-136	-	-	-	-	-	-	-	-
IHHMCIAP_00159	5.95e-65	-	-	-	K	ko:K06977	-	ko00000	acetyltransferase
IHHMCIAP_00160	6.54e-33	-	-	-	K	ko:K06977	-	ko00000	acetyltransferase
IHHMCIAP_00161	3.16e-182	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IHHMCIAP_00162	2.86e-286	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
IHHMCIAP_00163	4.06e-244	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IHHMCIAP_00164	4.59e-270	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
IHHMCIAP_00166	3.5e-171	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IHHMCIAP_00167	2.38e-123	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
IHHMCIAP_00168	6.77e-38	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
IHHMCIAP_00169	6.86e-13	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
IHHMCIAP_00170	6.44e-56	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
IHHMCIAP_00171	4.69e-23	ABC-SBP	-	-	S	ko:K01989,ko:K05832	-	ko00000,ko00002,ko02000	ABC transporter substrate binding protein
IHHMCIAP_00172	0.0	-	-	-	-	-	-	-	-
IHHMCIAP_00173	1.21e-130	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
IHHMCIAP_00174	1.26e-217	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
IHHMCIAP_00175	2.75e-243	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
IHHMCIAP_00176	1.16e-209	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
IHHMCIAP_00177	3.52e-106	dmpA	3.4.11.19	-	EQ	ko:K01266	-	ko00000,ko01000,ko01002	Peptidase family S58
IHHMCIAP_00179	2.61e-188	dppA	-	-	E	ko:K16203	-	ko00000,ko01000,ko01002	D-aminopeptidase
IHHMCIAP_00180	9.33e-119	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
IHHMCIAP_00181	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
IHHMCIAP_00182	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
IHHMCIAP_00183	1.43e-223	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
IHHMCIAP_00184	7.86e-242	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
IHHMCIAP_00185	9.5e-201	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IHHMCIAP_00186	2.12e-222	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IHHMCIAP_00187	2.72e-57	-	-	-	-	-	-	-	-
IHHMCIAP_00188	2.24e-238	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IHHMCIAP_00189	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IHHMCIAP_00190	2.28e-126	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IHHMCIAP_00191	1.9e-156	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
IHHMCIAP_00192	2.9e-313	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
IHHMCIAP_00193	2.7e-153	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
IHHMCIAP_00194	1.88e-273	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
IHHMCIAP_00195	1.65e-284	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
IHHMCIAP_00196	1.13e-252	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IHHMCIAP_00197	1.87e-126	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IHHMCIAP_00198	8.57e-161	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
IHHMCIAP_00199	1.33e-169	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
IHHMCIAP_00200	6.95e-301	ymfH	-	-	S	-	-	-	Peptidase M16
IHHMCIAP_00201	1.89e-293	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
IHHMCIAP_00202	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
IHHMCIAP_00203	1.81e-90	-	-	-	S	-	-	-	Protein of unknown function (DUF1149)
IHHMCIAP_00204	3.13e-133	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
IHHMCIAP_00205	5.85e-255	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
IHHMCIAP_00206	7.79e-85	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
IHHMCIAP_00212	3.07e-94	-	-	-	S	-	-	-	Virulence-associated protein E
IHHMCIAP_00215	1.62e-24	-	-	-	-	-	-	-	-
IHHMCIAP_00217	0.000202	puuR	-	-	K	-	-	-	domain protein
IHHMCIAP_00218	4.8e-113	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
IHHMCIAP_00219	1.18e-251	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
IHHMCIAP_00220	3.14e-189	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
IHHMCIAP_00221	7.7e-31	-	-	-	-	-	-	-	-
IHHMCIAP_00222	8.2e-220	rluD2	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
IHHMCIAP_00223	7.48e-192	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IHHMCIAP_00224	1.34e-145	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
IHHMCIAP_00225	4.73e-140	-	-	-	S	-	-	-	CYTH
IHHMCIAP_00226	3.15e-145	yjbH	-	-	Q	-	-	-	Thioredoxin
IHHMCIAP_00227	4.74e-210	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
IHHMCIAP_00228	1.5e-174	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
IHHMCIAP_00229	3.22e-90	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
IHHMCIAP_00230	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IHHMCIAP_00231	6.14e-53	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
IHHMCIAP_00233	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
IHHMCIAP_00234	4.54e-59	XK27_09445	-	-	S	-	-	-	Domain of unknown function (DUF1827)
IHHMCIAP_00235	5.57e-85	sufI	-	-	Q	-	-	-	Multicopper oxidase
IHHMCIAP_00236	7.37e-208	sufI	-	-	Q	-	-	-	Multicopper oxidase
IHHMCIAP_00237	2.8e-35	sufI	-	-	Q	-	-	-	Multicopper oxidase
IHHMCIAP_00238	9.06e-27	-	-	-	-	-	-	-	-
IHHMCIAP_00239	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IHHMCIAP_00240	1.07e-202	hlyX	-	-	S	ko:K03699	-	ko00000,ko02042	Transporter associated domain
IHHMCIAP_00241	2.48e-95	-	-	-	-	-	-	-	-
IHHMCIAP_00242	1.75e-110	-	-	-	-	-	-	-	-
IHHMCIAP_00243	1.89e-188	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
IHHMCIAP_00244	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IHHMCIAP_00245	3.03e-231	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
IHHMCIAP_00247	3.93e-218	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
IHHMCIAP_00248	9.11e-133	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
IHHMCIAP_00249	1.05e-62	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
IHHMCIAP_00250	3.34e-209	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
IHHMCIAP_00251	8.2e-102	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
IHHMCIAP_00252	1.74e-106	gtcA1	-	-	S	-	-	-	Teichoic acid glycosylation protein
IHHMCIAP_00253	1.67e-271	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
IHHMCIAP_00254	7.82e-34	-	-	-	-	-	-	-	-
IHHMCIAP_00255	0.0	-	-	-	E	-	-	-	Amino acid permease
IHHMCIAP_00257	0.0	speA	4.1.1.17, 4.1.1.18, 4.1.1.19	-	E	ko:K01581,ko:K01582,ko:K01585	ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Orn/Lys/Arg decarboxylase, C-terminal domain
IHHMCIAP_00258	2.15e-299	ynbB	-	-	P	-	-	-	aluminum resistance
IHHMCIAP_00259	5.67e-296	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
IHHMCIAP_00260	8.28e-233	pfoS/R	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
IHHMCIAP_00262	2.6e-314	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IHHMCIAP_00263	2.16e-282	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
IHHMCIAP_00264	6.11e-159	lys	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
IHHMCIAP_00265	1.14e-292	-	-	-	E	ko:K03294	-	ko00000	amino acid
IHHMCIAP_00266	5.18e-134	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
IHHMCIAP_00267	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
IHHMCIAP_00268	4.16e-31	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
IHHMCIAP_00270	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
IHHMCIAP_00271	3.82e-168	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
IHHMCIAP_00272	2.57e-222	rihC	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
IHHMCIAP_00273	2.48e-159	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IHHMCIAP_00274	3.71e-154	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
IHHMCIAP_00275	7.49e-208	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IHHMCIAP_00276	1.6e-114	-	-	-	-	-	-	-	-
IHHMCIAP_00277	5.09e-51	-	-	-	-	-	-	-	-
IHHMCIAP_00279	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
IHHMCIAP_00280	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IHHMCIAP_00281	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
IHHMCIAP_00282	1.83e-190	-	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
IHHMCIAP_00283	4.57e-142	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IHHMCIAP_00284	3.27e-142	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IHHMCIAP_00285	1.89e-192	glnH	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
IHHMCIAP_00286	4.64e-172	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IHHMCIAP_00287	1.45e-152	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Zeta toxin
IHHMCIAP_00288	5.48e-143	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Zeta toxin
IHHMCIAP_00290	2.02e-131	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
IHHMCIAP_00291	2.34e-266	pepA	-	-	E	-	-	-	M42 glutamyl aminopeptidase
IHHMCIAP_00292	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
IHHMCIAP_00293	9.39e-184	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
IHHMCIAP_00294	4.56e-154	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
IHHMCIAP_00295	4.83e-276	pmrA	-	-	EGP	ko:K08161	-	ko00000,ko02000	MFS_1 like family
IHHMCIAP_00296	3.11e-75	-	-	-	-	-	-	-	-
IHHMCIAP_00298	3.29e-45	proP	-	-	EGP	ko:K03761,ko:K03762	-	ko00000,ko02000	Sugar (and other) transporter
IHHMCIAP_00299	4.47e-129	proP	-	-	EGP	ko:K03761,ko:K03762	-	ko00000,ko02000	Sugar (and other) transporter
IHHMCIAP_00300	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
IHHMCIAP_00301	2.34e-215	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
IHHMCIAP_00302	0.0	ppc	4.1.1.31	-	H	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
IHHMCIAP_00303	1.61e-55	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
IHHMCIAP_00304	3.48e-18	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
IHHMCIAP_00305	4.6e-10	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
IHHMCIAP_00306	9.32e-70	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	transcriptional antiterminator
IHHMCIAP_00307	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
IHHMCIAP_00308	3.25e-112	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	AsnC family
IHHMCIAP_00309	2.21e-69	-	-	-	S	ko:K08987	-	ko00000	membrane
IHHMCIAP_00310	1.17e-34	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
IHHMCIAP_00312	1.13e-11	-	-	-	T	-	-	-	GGDEF domain
IHHMCIAP_00313	2.67e-90	-	-	-	T	-	-	-	Gaf domain
IHHMCIAP_00314	9.96e-124	-	3.6.1.22	-	L	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	ko00000,ko00001,ko01000	NUDIX domain
IHHMCIAP_00315	6.93e-161	alkD	-	-	L	-	-	-	DNA alkylation repair enzyme
IHHMCIAP_00316	3.26e-272	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
IHHMCIAP_00317	1.23e-143	-	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
IHHMCIAP_00318	1.64e-61	-	-	-	D	-	-	-	Di-iron-containing protein involved in the repair of iron-sulfur clusters
IHHMCIAP_00319	1.04e-45	copZ	-	-	P	-	-	-	Heavy-metal-associated domain
IHHMCIAP_00320	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
IHHMCIAP_00321	1.2e-87	-	-	-	C	-	-	-	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
IHHMCIAP_00322	3.86e-118	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
IHHMCIAP_00323	4.36e-155	-	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	Eukaryotic-type carbonic anhydrase
IHHMCIAP_00324	1.16e-205	-	-	-	L	ko:K07448	-	ko00000,ko02048	Mrr N-terminal domain
IHHMCIAP_00325	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IHHMCIAP_00326	2.18e-158	ybbB	-	-	S	-	-	-	Protein of unknown function (DUF1211)
IHHMCIAP_00327	5.36e-218	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
IHHMCIAP_00328	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IHHMCIAP_00329	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
IHHMCIAP_00330	3.99e-64	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IHHMCIAP_00331	5.43e-257	camS	-	-	S	-	-	-	sex pheromone
IHHMCIAP_00332	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IHHMCIAP_00333	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
IHHMCIAP_00334	1.44e-147	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
IHHMCIAP_00335	7.97e-131	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
IHHMCIAP_00337	2.99e-119	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
IHHMCIAP_00338	3.33e-140	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
IHHMCIAP_00340	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
IHHMCIAP_00341	2.23e-194	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
IHHMCIAP_00342	1.77e-174	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
IHHMCIAP_00343	1.51e-260	-	-	-	M	-	-	-	Glycosyl transferases group 1
IHHMCIAP_00344	4.83e-173	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
IHHMCIAP_00345	0.0	epsU	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
IHHMCIAP_00346	1.15e-282	-	-	-	M	-	-	-	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
IHHMCIAP_00348	3.45e-83	-	-	-	-	-	-	-	-
IHHMCIAP_00349	1.51e-299	-	-	-	-	-	-	-	-
IHHMCIAP_00350	1.79e-27	-	-	-	-	-	-	-	-
IHHMCIAP_00351	9.39e-73	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
IHHMCIAP_00352	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
IHHMCIAP_00355	1.51e-163	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
IHHMCIAP_00356	7.01e-213	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
IHHMCIAP_00357	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
IHHMCIAP_00358	2.69e-178	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
IHHMCIAP_00359	1.49e-308	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IHHMCIAP_00360	8.61e-223	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IHHMCIAP_00361	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IHHMCIAP_00362	1.28e-45	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
IHHMCIAP_00363	2.84e-143	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
IHHMCIAP_00364	8.37e-66	-	-	-	-	-	-	-	-
IHHMCIAP_00365	5.6e-45	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	transmembrane transport
IHHMCIAP_00366	1.2e-17	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
IHHMCIAP_00367	3.4e-61	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	transmembrane transport
IHHMCIAP_00368	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
IHHMCIAP_00369	5.49e-197	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
IHHMCIAP_00370	7.83e-205	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
IHHMCIAP_00371	2.38e-43	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IHHMCIAP_00372	0.0	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IHHMCIAP_00373	4.56e-198	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IHHMCIAP_00374	7.64e-88	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IHHMCIAP_00375	6.3e-95	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
IHHMCIAP_00376	8.59e-133	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IHHMCIAP_00377	3.27e-256	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
IHHMCIAP_00378	2.67e-64	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
IHHMCIAP_00379	5.61e-65	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
IHHMCIAP_00380	6.33e-87	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
IHHMCIAP_00381	9.07e-119	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
IHHMCIAP_00382	4.84e-73	livF	-	-	E	ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
IHHMCIAP_00383	1.13e-308	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
IHHMCIAP_00384	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
IHHMCIAP_00385	2.37e-141	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IHHMCIAP_00386	2.39e-253	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
IHHMCIAP_00387	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IHHMCIAP_00388	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IHHMCIAP_00389	1.98e-162	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IHHMCIAP_00390	8.7e-52	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IHHMCIAP_00391	5.04e-173	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
IHHMCIAP_00392	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IHHMCIAP_00393	1.94e-270	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IHHMCIAP_00394	6.03e-109	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IHHMCIAP_00395	1.66e-55	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2087)
IHHMCIAP_00396	5.85e-275	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
IHHMCIAP_00397	2.39e-287	-	-	-	-	-	-	-	-
IHHMCIAP_00398	0.0	-	-	-	S	-	-	-	SH3-like domain
IHHMCIAP_00399	0.0	traI	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
IHHMCIAP_00401	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
IHHMCIAP_00402	3.42e-276	-	-	-	EGP	-	-	-	Major Facilitator
IHHMCIAP_00403	1.07e-193	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
IHHMCIAP_00404	8.22e-217	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
IHHMCIAP_00405	3.42e-89	-	-	-	L	-	-	-	DDE superfamily endonuclease
IHHMCIAP_00406	5.17e-19	-	-	-	L	-	-	-	Transposase
IHHMCIAP_00407	1.32e-295	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
IHHMCIAP_00408	3.68e-165	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
IHHMCIAP_00409	1.16e-239	add	3.5.4.2, 3.5.4.4	-	F	ko:K01488,ko:K02029,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IHHMCIAP_00410	4.33e-75	-	-	-	-	-	-	-	-
IHHMCIAP_00413	9.5e-239	manL	2.7.1.191	-	G	ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
IHHMCIAP_00414	9.98e-179	manY	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
IHHMCIAP_00415	6.24e-215	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
IHHMCIAP_00416	1.35e-82	-	-	-	S	-	-	-	Domain of unknown function (DUF956)
IHHMCIAP_00417	3.77e-08	-	-	-	-	-	-	-	-
IHHMCIAP_00418	4e-313	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
IHHMCIAP_00419	2.01e-208	-	3.4.14.13	-	M	ko:K20742	-	ko00000,ko01000,ko01002	NlpC/P60 family
IHHMCIAP_00421	2.17e-10	-	-	-	K	-	-	-	Helix-turn-helix domain
IHHMCIAP_00422	1.36e-242	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
IHHMCIAP_00423	0.0	-	-	-	L	-	-	-	Helicase conserved C-terminal domain
IHHMCIAP_00424	3.39e-63	-	-	-	-	-	-	-	-
IHHMCIAP_00427	2.95e-283	oxlT	-	-	P	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
IHHMCIAP_00428	2.09e-25	malS	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Glycogen debranching enzyme, glucanotransferase domain
IHHMCIAP_00429	4.49e-175	malS	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Glycogen debranching enzyme, glucanotransferase domain
IHHMCIAP_00430	6.54e-59	malS	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Glycogen debranching enzyme, glucanotransferase domain
IHHMCIAP_00432	1.9e-259	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
IHHMCIAP_00433	1.62e-265	-	-	-	G	-	-	-	Major Facilitator Superfamily
IHHMCIAP_00434	3.21e-48	-	-	-	L	ko:K07497	-	ko00000	COG2963 Transposase and inactivated derivatives
IHHMCIAP_00435	9.63e-260	-	-	-	G	-	-	-	Major Facilitator Superfamily
IHHMCIAP_00436	2.92e-74	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
IHHMCIAP_00437	0.0	-	-	-	E	-	-	-	Amino acid permease
IHHMCIAP_00438	0.0	speA	4.1.1.17, 4.1.1.18, 4.1.1.19	-	E	ko:K01581,ko:K01582,ko:K01585	ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Orn/Lys/Arg decarboxylase, C-terminal domain
IHHMCIAP_00439	4.71e-98	malZ	3.2.1.20, 3.2.1.41	CBM48,GH13,GH31	G	ko:K01187,ko:K01200	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
IHHMCIAP_00440	1.96e-158	malZ	3.2.1.20, 3.2.1.41	CBM48,GH13,GH31	G	ko:K01187,ko:K01200	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
IHHMCIAP_00441	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
IHHMCIAP_00442	9.39e-256	-	2.7.1.11, 2.7.1.90	-	F	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
IHHMCIAP_00443	1.86e-103	-	2.7.1.211	-	G	ko:K02755,ko:K02756,ko:K02757,ko:K02777,ko:K02808,ko:K02809,ko:K02810	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
IHHMCIAP_00444	2.72e-72	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
IHHMCIAP_00445	1.56e-136	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
IHHMCIAP_00446	1.52e-175	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
IHHMCIAP_00447	3.18e-34	-	-	-	-	-	-	-	-
IHHMCIAP_00448	3.2e-137	yiiE	-	-	S	-	-	-	Protein of unknown function (DUF1211)
IHHMCIAP_00449	1.4e-127	-	2.3.1.128	-	K	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
IHHMCIAP_00453	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
IHHMCIAP_00454	3.72e-203	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
IHHMCIAP_00458	2.41e-128	-	-	-	M	-	-	-	LysM domain protein
IHHMCIAP_00459	7.1e-197	-	-	-	D	-	-	-	nuclear chromosome segregation
IHHMCIAP_00460	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Fumarase C C-terminus
IHHMCIAP_00461	2.46e-10	-	-	-	K	ko:K02530	-	ko00000,ko03000	DeoR C terminal sensor domain
IHHMCIAP_00462	1.7e-213	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
IHHMCIAP_00463	9.91e-59	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
IHHMCIAP_00464	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
IHHMCIAP_00465	9.02e-177	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
IHHMCIAP_00466	5.45e-48	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase
IHHMCIAP_00468	1.18e-250	ykfB	5.1.1.20	-	M	ko:K19802	-	ko00000,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
IHHMCIAP_00469	1.58e-122	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
IHHMCIAP_00470	2.77e-140	thiJ	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
IHHMCIAP_00471	1.09e-159	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
IHHMCIAP_00472	5.92e-165	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
IHHMCIAP_00473	2.88e-39	-	-	-	-	-	-	-	-
IHHMCIAP_00474	8.57e-41	-	-	-	-	-	-	-	-
IHHMCIAP_00475	1.02e-160	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IHHMCIAP_00476	8.76e-104	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
IHHMCIAP_00477	4.68e-234	-	-	-	S	-	-	-	AAA domain
IHHMCIAP_00479	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
IHHMCIAP_00480	7.39e-65	-	-	-	-	-	-	-	-
IHHMCIAP_00481	1.09e-128	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
IHHMCIAP_00482	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IHHMCIAP_00483	4.02e-237	-	-	-	M	-	-	-	Glycosyl transferase family 8
IHHMCIAP_00484	3.18e-88	-	-	-	T	-	-	-	domain protein
IHHMCIAP_00485	4.29e-189	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
IHHMCIAP_00488	1.4e-22	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
IHHMCIAP_00489	1.24e-147	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
IHHMCIAP_00490	4.71e-149	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IHHMCIAP_00491	4.33e-192	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
IHHMCIAP_00492	1.28e-91	-	-	-	I	-	-	-	Psort location Cytoplasmic, score
IHHMCIAP_00493	3.82e-77	-	-	-	I	-	-	-	acetylesterase activity
IHHMCIAP_00494	1.07e-241	-	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IHHMCIAP_00495	0.0	yuxL	3.4.19.1	-	E	ko:K01303	-	ko00000,ko01000,ko01002	Prolyl oligopeptidase family
IHHMCIAP_00496	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
IHHMCIAP_00497	6.44e-152	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
IHHMCIAP_00498	2.12e-136	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
IHHMCIAP_00499	5.35e-85	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
IHHMCIAP_00500	1.01e-278	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
IHHMCIAP_00501	1.65e-135	XK27_01810	-	-	S	-	-	-	Calcineurin-like phosphoesterase
IHHMCIAP_00502	1.93e-84	XK27_01810	-	-	S	-	-	-	Calcineurin-like phosphoesterase
IHHMCIAP_00503	7.43e-77	-	-	-	-	-	-	-	-
IHHMCIAP_00504	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
IHHMCIAP_00505	1.3e-99	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IHHMCIAP_00506	1.95e-218	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
IHHMCIAP_00507	1.88e-251	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
IHHMCIAP_00508	0.0	carB1	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
IHHMCIAP_00509	4.02e-58	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
IHHMCIAP_00510	1.39e-313	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
IHHMCIAP_00511	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
IHHMCIAP_00512	4.83e-85	-	-	-	S	-	-	-	EDD domain protein, DegV family
IHHMCIAP_00513	4.22e-103	-	-	-	S	-	-	-	EDD domain protein, DegV family
IHHMCIAP_00514	2.5e-238	-	-	-	-	-	-	-	-
IHHMCIAP_00515	5.54e-213	-	-	-	EG	-	-	-	EamA-like transporter family
IHHMCIAP_00516	9.2e-154	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IHHMCIAP_00517	1.55e-110	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IHHMCIAP_00518	2.77e-105	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IHHMCIAP_00519	6.8e-106	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IHHMCIAP_00520	5.73e-149	pgm1	-	-	G	-	-	-	phosphoglycerate mutase
IHHMCIAP_00521	2.84e-16	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
IHHMCIAP_00522	3.44e-117	yfhC	-	-	C	-	-	-	Nitroreductase family
IHHMCIAP_00523	4e-57	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
IHHMCIAP_00524	5.33e-91	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
IHHMCIAP_00526	2.38e-227	xerS	-	-	L	ko:K03733	-	ko00000,ko03036	Belongs to the 'phage' integrase family
IHHMCIAP_00527	1.21e-265	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
IHHMCIAP_00528	6.23e-267	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
IHHMCIAP_00529	1.81e-99	-	-	-	S	ko:K07126	-	ko00000	Sel1-like repeats.
IHHMCIAP_00530	3.49e-60	-	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
IHHMCIAP_00531	6.19e-102	-	-	-	GM	-	-	-	NmrA-like family
IHHMCIAP_00532	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
IHHMCIAP_00533	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
IHHMCIAP_00534	1.76e-173	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
IHHMCIAP_00535	2.29e-222	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
IHHMCIAP_00536	1.54e-159	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
IHHMCIAP_00537	3.33e-41	-	-	-	K	-	-	-	LysR substrate binding domain
IHHMCIAP_00538	4.81e-48	-	-	-	L	-	-	-	DDE superfamily endonuclease
IHHMCIAP_00540	6.31e-159	WQ51_05710	-	-	S	-	-	-	Mitochondrial biogenesis AIM24
IHHMCIAP_00541	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
IHHMCIAP_00542	7.57e-10	-	-	-	Q	-	-	-	Methyltransferase domain
IHHMCIAP_00545	1.17e-119	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
IHHMCIAP_00546	3.28e-141	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
IHHMCIAP_00547	1.48e-38	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
IHHMCIAP_00548	2.26e-49	-	-	-	-	-	-	-	-
IHHMCIAP_00549	1.15e-169	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
IHHMCIAP_00552	8.71e-201	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
IHHMCIAP_00553	3.05e-205	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
IHHMCIAP_00554	4.17e-202	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
IHHMCIAP_00555	9.06e-182	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IHHMCIAP_00556	1.98e-147	-	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
IHHMCIAP_00557	2.5e-161	phoB	-	-	T	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
IHHMCIAP_00558	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IHHMCIAP_00559	9.63e-52	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
IHHMCIAP_00560	3.58e-107	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
IHHMCIAP_00562	3.17e-156	-	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
IHHMCIAP_00563	1.78e-240	-	-	-	S	-	-	-	Glycosyl hydrolases family 18
IHHMCIAP_00564	6.6e-134	M1-740	-	-	I	-	-	-	NUDIX domain
IHHMCIAP_00565	1.74e-128	-	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
IHHMCIAP_00566	2.21e-179	-	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
IHHMCIAP_00567	4.13e-188	-	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
IHHMCIAP_00568	8.58e-174	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
IHHMCIAP_00569	1.43e-135	-	-	-	T	ko:K16923	-	ko00000,ko00002,ko02000	phosphorelay sensor kinase activity
IHHMCIAP_00571	4.57e-87	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
IHHMCIAP_00572	3.87e-262	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
IHHMCIAP_00573	4.56e-243	-	-	-	T	-	-	-	diguanylate cyclase
IHHMCIAP_00574	2.98e-135	-	-	-	-	-	-	-	-
IHHMCIAP_00575	1.11e-194	-	-	-	G	-	-	-	Sucrose-6F-phosphate phosphohydrolase
IHHMCIAP_00576	0.000638	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
IHHMCIAP_00577	1.82e-65	-	-	-	V	ko:K06147	-	ko00000,ko02000	(ABC) transporter
IHHMCIAP_00578	1.63e-07	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
IHHMCIAP_00579	2.39e-55	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
IHHMCIAP_00580	1.05e-68	-	-	-	V	ko:K06147	-	ko00000,ko02000	abc transporter atp-binding protein
IHHMCIAP_00581	2.51e-235	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
IHHMCIAP_00582	3.97e-38	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
IHHMCIAP_00583	1.1e-144	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
IHHMCIAP_00584	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IHHMCIAP_00585	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IHHMCIAP_00586	1.66e-218	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
IHHMCIAP_00587	1.13e-247	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
IHHMCIAP_00588	5.48e-260	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
IHHMCIAP_00589	1.22e-224	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
IHHMCIAP_00590	7.03e-216	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	GHMP kinases N terminal domain
IHHMCIAP_00591	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
IHHMCIAP_00592	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
IHHMCIAP_00593	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
IHHMCIAP_00594	4.66e-93	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
IHHMCIAP_00595	7.33e-187	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	EXOIII
IHHMCIAP_00596	3.09e-139	-	-	-	S	-	-	-	YjbR
IHHMCIAP_00597	1.39e-183	-	-	-	S	-	-	-	Gram-negative-bacterium-type cell wall biogenesis
IHHMCIAP_00598	1.47e-53	pat	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
IHHMCIAP_00599	1.61e-96	-	-	-	C	-	-	-	FMN_bind
IHHMCIAP_00600	1.04e-184	-	-	-	C	-	-	-	FMN_bind
IHHMCIAP_00601	2.28e-26	pat	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
IHHMCIAP_00603	2.41e-16	-	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	EcoEI R protein C-terminal
IHHMCIAP_00604	2.92e-286	-	-	-	S	ko:K06915	-	ko00000	Domain of unknown function DUF87
IHHMCIAP_00605	2.86e-197	-	-	-	S	-	-	-	SIR2-like domain
IHHMCIAP_00607	1.14e-113	-	-	-	L	ko:K07448	-	ko00000,ko02048	restriction endonuclease
IHHMCIAP_00609	0.0	hsdR	3.1.21.3	-	F	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
IHHMCIAP_00610	5.28e-123	-	-	-	V	-	-	-	Type I restriction modification DNA specificity domain
IHHMCIAP_00611	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	COG COG0286 Type I restriction-modification system methyltransferase subunit
IHHMCIAP_00612	2.36e-23	-	-	-	L	ko:K07473	-	ko00000,ko02048	Addiction module antitoxin, RelB DinJ family
IHHMCIAP_00613	8.91e-170	-	-	-	L	-	-	-	COG3547 Transposase and inactivated derivatives
IHHMCIAP_00614	2.22e-96	-	-	-	L	-	-	-	COG3547 Transposase and inactivated derivatives
IHHMCIAP_00615	5.5e-202	-	-	-	V	-	-	-	LD-carboxypeptidase
IHHMCIAP_00616	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
IHHMCIAP_00617	1.48e-223	-	-	-	-	-	-	-	-
IHHMCIAP_00618	7.45e-178	-	-	-	-	-	-	-	-
IHHMCIAP_00619	4.3e-36	-	-	-	-	-	-	-	-
IHHMCIAP_00620	3.33e-146	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
IHHMCIAP_00621	3.03e-179	prsW	-	-	S	-	-	-	Involved in the degradation of specific anti-sigma factors
IHHMCIAP_00622	2.46e-93	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
IHHMCIAP_00623	1.73e-24	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
IHHMCIAP_00624	7.85e-46	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
IHHMCIAP_00625	0.0	gapN	1.2.1.9	-	C	ko:K00131	ko00010,ko00030,ko01100,ko01120,ko01200,map00010,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
IHHMCIAP_00626	0.0	-	-	-	EM	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
IHHMCIAP_00627	4.75e-216	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
IHHMCIAP_00628	4.87e-101	ywnA	-	-	K	-	-	-	Transcriptional regulator
IHHMCIAP_00629	1.79e-86	-	-	-	GM	-	-	-	NmrA-like family
IHHMCIAP_00630	2.16e-210	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Peptidase family M48
IHHMCIAP_00631	7.58e-289	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
IHHMCIAP_00632	0.0	prtP	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
IHHMCIAP_00633	1.22e-25	-	-	-	K	-	-	-	GNAT family
IHHMCIAP_00634	2.37e-98	-	-	-	-	-	-	-	-
IHHMCIAP_00635	6.16e-138	apl	3.1.3.1	-	S	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	SNARE associated Golgi protein
IHHMCIAP_00636	5.84e-253	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
IHHMCIAP_00642	1.63e-278	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IHHMCIAP_00643	0.0	bmr3_1	-	-	EGP	ko:K18935	-	ko00000,ko02000	Sugar (and other) transporter
IHHMCIAP_00644	8.07e-155	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
IHHMCIAP_00645	2.24e-184	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
IHHMCIAP_00646	1.11e-25	-	-	-	L	-	-	-	transposase and inactivated derivatives, IS30 family
IHHMCIAP_00647	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
IHHMCIAP_00648	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
IHHMCIAP_00649	3.66e-103	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
IHHMCIAP_00650	6.16e-54	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
IHHMCIAP_00651	2.23e-105	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
IHHMCIAP_00652	9.16e-69	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
IHHMCIAP_00653	4.88e-88	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
IHHMCIAP_00654	5.2e-222	-	-	-	-	-	-	-	-
IHHMCIAP_00655	6.42e-182	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
IHHMCIAP_00656	1.03e-50	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
IHHMCIAP_00657	7.69e-98	-	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain
IHHMCIAP_00659	7.15e-295	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
IHHMCIAP_00660	4.69e-202	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IHHMCIAP_00661	0.0	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
IHHMCIAP_00663	1.4e-47	-	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
IHHMCIAP_00664	5.3e-99	-	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
IHHMCIAP_00665	3.25e-79	-	-	-	-	-	-	-	-
IHHMCIAP_00666	6.37e-76	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
IHHMCIAP_00667	7.36e-18	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
IHHMCIAP_00668	7.46e-36	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
IHHMCIAP_00669	9.99e-216	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
IHHMCIAP_00670	7.86e-207	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
IHHMCIAP_00671	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
IHHMCIAP_00672	3.16e-73	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
IHHMCIAP_00673	1.54e-289	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
IHHMCIAP_00674	0.0	yhaN	-	-	L	-	-	-	AAA domain
IHHMCIAP_00675	1.28e-229	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
IHHMCIAP_00676	1.81e-86	aroK	1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4	-	F	ko:K00014,ko:K00891,ko:K03785,ko:K03786,ko:K13829,ko:K15546	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko03000	shikimate kinase activity
IHHMCIAP_00677	5.07e-64	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
IHHMCIAP_00678	8.28e-199	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
IHHMCIAP_00679	9.14e-146	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IHHMCIAP_00680	2.5e-173	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
IHHMCIAP_00681	5.79e-218	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
IHHMCIAP_00682	4.02e-71	-	-	-	-	-	-	-	-
IHHMCIAP_00683	1.67e-104	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
IHHMCIAP_00684	3.02e-176	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IHHMCIAP_00685	1.89e-276	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
IHHMCIAP_00686	1.64e-158	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
IHHMCIAP_00687	9.52e-72	ytpP	-	-	CO	-	-	-	Thioredoxin
IHHMCIAP_00688	1.2e-154	XK27_10290	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IHHMCIAP_00689	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
IHHMCIAP_00690	2.08e-104	-	-	-	K	-	-	-	Helix-turn-helix domain
IHHMCIAP_00691	4.38e-84	-	-	-	L	-	-	-	MobA MobL family protein
IHHMCIAP_00692	1.47e-83	-	-	-	S	-	-	-	Domain of unknown function DUF1828
IHHMCIAP_00693	6.13e-278	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
IHHMCIAP_00694	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
IHHMCIAP_00695	9.14e-217	ynbB	-	-	P	-	-	-	aluminum resistance
IHHMCIAP_00696	1.87e-218	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IHHMCIAP_00697	8.9e-92	yqhL	-	-	P	-	-	-	Rhodanese-like protein
IHHMCIAP_00698	2.98e-45	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
IHHMCIAP_00699	5.6e-148	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Rhomboid family
IHHMCIAP_00700	4.78e-135	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IHHMCIAP_00701	2.18e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
IHHMCIAP_00702	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
IHHMCIAP_00703	0.0	-	-	-	S	-	-	-	membrane
IHHMCIAP_00704	2.55e-105	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IHHMCIAP_00705	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IHHMCIAP_00706	2.39e-253	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IHHMCIAP_00707	9.83e-81	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
IHHMCIAP_00708	8.95e-174	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IHHMCIAP_00709	5.39e-61	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
IHHMCIAP_00710	4.75e-202	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IHHMCIAP_00711	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IHHMCIAP_00712	1.96e-164	csrR	-	-	K	-	-	-	response regulator
IHHMCIAP_00713	2.09e-130	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
IHHMCIAP_00714	1.68e-273	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
IHHMCIAP_00715	1.46e-77	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
IHHMCIAP_00716	6.76e-143	yqeK	-	-	H	-	-	-	Hydrolase, HD family
IHHMCIAP_00717	1.58e-153	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IHHMCIAP_00718	1.16e-270	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
IHHMCIAP_00719	2.91e-74	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IHHMCIAP_00720	1.37e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
IHHMCIAP_00721	3.99e-112	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IHHMCIAP_00722	0.0	-	-	-	L	-	-	-	Putative transposase DNA-binding domain
IHHMCIAP_00723	2.29e-145	-	-	-	L	-	-	-	Resolvase, N terminal domain
IHHMCIAP_00724	0.0	-	-	-	S	ko:K06921	-	ko00000	Archaea bacterial proteins of unknown function
IHHMCIAP_00725	7.36e-44	-	-	-	-	-	-	-	-
IHHMCIAP_00726	2.73e-58	-	-	-	-	-	-	-	-
IHHMCIAP_00727	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IHHMCIAP_00728	4.07e-217	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
IHHMCIAP_00729	3.85e-314	dnaB2	-	-	L	ko:K03346	-	ko00000,ko03032	Replication initiation and membrane attachment
IHHMCIAP_00730	1.57e-107	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IHHMCIAP_00731	1.03e-131	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IHHMCIAP_00732	2.53e-203	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
IHHMCIAP_00733	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IHHMCIAP_00734	2.79e-48	-	-	-	EGP	-	-	-	Major Facilitator
IHHMCIAP_00735	4.4e-90	-	-	-	EGP	-	-	-	Major Facilitator
IHHMCIAP_00736	1.16e-48	-	-	-	EGP	-	-	-	Major facilitator Superfamily
IHHMCIAP_00737	1.08e-36	-	-	-	L	-	-	-	Transposase
IHHMCIAP_00738	1.38e-37	-	-	-	-	-	-	-	-
IHHMCIAP_00740	2.59e-199	-	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
IHHMCIAP_00741	6.63e-125	-	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IHHMCIAP_00742	1.39e-101	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
IHHMCIAP_00743	5.76e-52	axe	-	-	K	ko:K21498	-	ko00000,ko02048	Helix-turn-helix XRE-family like proteins
IHHMCIAP_00744	2.5e-09	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
IHHMCIAP_00745	1.22e-251	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
IHHMCIAP_00746	3.76e-78	XK27_02085	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IHHMCIAP_00747	3.07e-225	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
IHHMCIAP_00748	5.85e-15	-	-	-	-	-	-	-	-
IHHMCIAP_00749	2.21e-197	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
IHHMCIAP_00750	1.59e-144	-	-	-	L	-	-	-	nuclease
IHHMCIAP_00751	1.31e-17	XK27_02085	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IHHMCIAP_00752	5.44e-149	-	-	-	V	ko:K19147	-	ko00000,ko02048	McrBC 5-methylcytosine restriction system component
IHHMCIAP_00753	0.0	-	-	-	V	ko:K07452	-	ko00000,ko01000,ko02048	AAA domain (dynein-related subfamily)
IHHMCIAP_00754	7.58e-49	-	-	-	L	-	-	-	Transposase and inactivated derivatives
IHHMCIAP_00755	5.26e-129	-	-	-	L	-	-	-	Transposase and inactivated derivatives
IHHMCIAP_00756	6.13e-257	-	-	GT4	M	ko:K19424	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
IHHMCIAP_00757	9.32e-21	-	-	-	S	-	-	-	Core-2/I-Branching enzyme
IHHMCIAP_00759	2.87e-43	-	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Rossmann-like domain
IHHMCIAP_00760	6.14e-143	-	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
IHHMCIAP_00761	4.75e-90	-	-	-	L	-	-	-	DDE superfamily endonuclease
IHHMCIAP_00762	1.02e-37	-	-	-	L	-	-	-	DDE superfamily endonuclease
IHHMCIAP_00763	5.49e-53	-	-	-	L	-	-	-	DDE superfamily endonuclease
IHHMCIAP_00764	1.18e-36	-	-	-	M	-	-	-	Glycosyl transferases group 1
IHHMCIAP_00765	2.92e-240	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
IHHMCIAP_00767	5.29e-112	-	-	-	M	-	-	-	Domain of unknown function (DUF4422)
IHHMCIAP_00768	2.84e-109	-	-	-	S	-	-	-	Glycosyltransferase family 28 C-terminal domain
IHHMCIAP_00769	4.69e-113	-	-	-	M	-	-	-	Oligosaccharide biosynthesis protein Alg14 like
IHHMCIAP_00770	1.19e-156	epsE2	-	-	M	-	-	-	Bacterial sugar transferase
IHHMCIAP_00771	3.29e-187	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
IHHMCIAP_00772	7.58e-151	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
IHHMCIAP_00773	1.33e-157	epsB	-	-	M	-	-	-	biosynthesis protein
IHHMCIAP_00774	1.04e-229	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
IHHMCIAP_00775	1.53e-237	pbpX1	-	-	V	-	-	-	Beta-lactamase
IHHMCIAP_00776	7.81e-37	-	-	-	-	-	-	-	-
IHHMCIAP_00777	4.25e-251	-	-	-	S	-	-	-	Protein of unknown function DUF262
IHHMCIAP_00778	7.88e-75	-	-	-	S	-	-	-	Putative inner membrane protein (DUF1819)
IHHMCIAP_00779	4.86e-73	-	-	-	S	-	-	-	Domain of unknown function (DUF1788)
IHHMCIAP_00780	0.0	-	-	-	K	-	-	-	RNA-binding protein homologous to eukaryotic snRNP
IHHMCIAP_00781	0.0	-	-	-	V	-	-	-	restriction
IHHMCIAP_00782	1.04e-293	-	-	-	S	-	-	-	TIGR02687 family
IHHMCIAP_00783	0.0	-	3.4.21.53	-	O	ko:K01338	ko04112,map04112	ko00000,ko00001,ko01000,ko01002	Putative ATP-dependent Lon protease
IHHMCIAP_00785	1.88e-164	ogt	2.1.1.63	-	L	ko:K00567,ko:K13531	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IHHMCIAP_00786	3.9e-179	-	-	-	S	-	-	-	Peptidase family M23
IHHMCIAP_00787	7.34e-104	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
IHHMCIAP_00788	1.13e-155	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
IHHMCIAP_00789	7.8e-194	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IHHMCIAP_00790	2.26e-308	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
IHHMCIAP_00791	3.04e-32	-	-	-	-	-	-	-	-
IHHMCIAP_00792	1.37e-133	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
IHHMCIAP_00793	2.25e-204	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
IHHMCIAP_00794	6.29e-71	-	-	-	S	-	-	-	Alpha beta hydrolase
IHHMCIAP_00796	1.37e-33	maa	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Psort location Cytoplasmic, score
IHHMCIAP_00797	6.67e-194	-	-	-	L	-	-	-	DDE superfamily endonuclease
IHHMCIAP_00798	4.73e-65	-	-	-	S	-	-	-	SLAP domain
IHHMCIAP_00799	8.33e-138	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
IHHMCIAP_00802	9.88e-246	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
IHHMCIAP_00803	4.26e-108	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
IHHMCIAP_00804	2.71e-35	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
IHHMCIAP_00805	5.11e-18	-	-	-	C	-	-	-	Pyridoxamine 5'-phosphate oxidase
IHHMCIAP_00806	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
IHHMCIAP_00807	5.8e-168	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IHHMCIAP_00808	4.97e-93	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Low molecular weight phosphotyrosine protein phosphatase
IHHMCIAP_00809	9.53e-99	-	-	-	-	-	-	-	-
IHHMCIAP_00810	3.85e-103	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
IHHMCIAP_00811	5.03e-105	cylB	-	-	V	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
IHHMCIAP_00812	2.57e-138	-	-	-	L	-	-	-	Integrase
IHHMCIAP_00813	5.89e-41	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
IHHMCIAP_00814	1.01e-95	-	-	-	K	-	-	-	3.5.2 Transcription regulation
IHHMCIAP_00815	1.38e-276	-	-	-	V	-	-	-	drug transmembrane transporter activity
IHHMCIAP_00817	8.93e-45	-	-	-	T	-	-	-	diguanylate cyclase activity
IHHMCIAP_00818	4.59e-32	carA	6.3.5.5	-	F	ko:K01955,ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
IHHMCIAP_00819	5.9e-198	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
IHHMCIAP_00820	0.0	carB	-	-	F	-	-	-	Psort location Cytoplasmic, score 8.87
IHHMCIAP_00821	7.11e-29	-	-	-	V	ko:K06147	-	ko00000,ko02000	(ABC) transporter
IHHMCIAP_00822	1.93e-117	ybaJ	-	-	Q	-	-	-	Hypothetical methyltransferase
IHHMCIAP_00823	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IHHMCIAP_00824	8.99e-104	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
IHHMCIAP_00825	3.35e-97	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
IHHMCIAP_00826	1.28e-61	-	-	-	Q	-	-	-	phosphatase activity
IHHMCIAP_00827	4.16e-239	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase, type I
IHHMCIAP_00828	1.41e-98	-	-	-	K	-	-	-	DNA-binding transcription factor activity
IHHMCIAP_00829	5.71e-08	tyrA	1.3.1.12, 5.4.99.5	-	E	ko:K14187	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	chorismate mutase
IHHMCIAP_00830	1.26e-101	-	-	-	S	-	-	-	Aminoacyl-tRNA editing domain
IHHMCIAP_00831	1.67e-222	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
IHHMCIAP_00832	2.33e-212	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
IHHMCIAP_00833	9.96e-25	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
IHHMCIAP_00834	2.96e-217	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
IHHMCIAP_00835	0.0	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
IHHMCIAP_00836	7.71e-165	-	-	-	F	-	-	-	Phosphorylase superfamily
IHHMCIAP_00838	3.63e-165	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IHHMCIAP_00839	3.78e-168	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IHHMCIAP_00840	4.74e-177	fliY	-	-	ET	ko:K02030,ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
IHHMCIAP_00842	2.65e-305	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
IHHMCIAP_00843	1.64e-40	-	-	-	K	-	-	-	Transcriptional regulator
IHHMCIAP_00844	3.64e-101	-	-	-	K	-	-	-	Transcriptional regulator
IHHMCIAP_00845	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
IHHMCIAP_00846	0.0	-	-	-	KLT	-	-	-	Protein kinase domain
IHHMCIAP_00847	7.29e-84	-	-	-	S	-	-	-	HicB family
IHHMCIAP_00848	5.02e-52	-	-	-	S	-	-	-	HicA toxin of bacterial toxin-antitoxin,
IHHMCIAP_00849	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
IHHMCIAP_00850	2.95e-263	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IHHMCIAP_00851	2.76e-129	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
IHHMCIAP_00852	8.92e-290	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
IHHMCIAP_00853	6.71e-85	-	-	-	-	-	-	-	-
IHHMCIAP_00854	0.0	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
IHHMCIAP_00855	4.21e-242	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IHHMCIAP_00856	9.69e-317	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IHHMCIAP_00857	5.07e-103	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IHHMCIAP_00858	6.11e-96	-	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
IHHMCIAP_00859	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Papain family cysteine protease
IHHMCIAP_00860	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
IHHMCIAP_00861	1.33e-227	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IHHMCIAP_00862	2.78e-251	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IHHMCIAP_00863	3.19e-239	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IHHMCIAP_00864	1.09e-200	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IHHMCIAP_00865	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
IHHMCIAP_00866	3.28e-128	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
IHHMCIAP_00867	5.9e-160	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
IHHMCIAP_00868	5.19e-42	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	transmembrane transport
IHHMCIAP_00869	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
IHHMCIAP_00870	4.99e-264	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
IHHMCIAP_00872	3.18e-155	ypgQ	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
IHHMCIAP_00873	1.8e-311	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
IHHMCIAP_00874	7.66e-251	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
IHHMCIAP_00875	6.38e-141	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
IHHMCIAP_00876	2.29e-297	amd	-	-	E	-	-	-	Peptidase family M20/M25/M40
IHHMCIAP_00877	4.17e-102	steT	-	-	E	ko:K03294	-	ko00000	amino acid
IHHMCIAP_00878	4.09e-80	-	-	-	S	ko:K07006	-	ko00000	Pyridoxamine 5'-phosphate oxidase
IHHMCIAP_00880	7.93e-309	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IHHMCIAP_00883	1.46e-204	cjaA	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
IHHMCIAP_00884	3.4e-174	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IHHMCIAP_00885	1.39e-121	glnP7	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter permease
IHHMCIAP_00886	1.32e-144	glnP9	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter, permease protein
IHHMCIAP_00887	4.67e-127	-	3.6.1.67	-	F	ko:K19965	ko00790,map00790	ko00000,ko00001,ko00002,ko01000	NUDIX domain
IHHMCIAP_00888	9.47e-120	-	-	-	L	-	-	-	DDE superfamily endonuclease
IHHMCIAP_00889	1.68e-70	-	-	-	S	-	-	-	Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units
IHHMCIAP_00890	0.0	XK27_08315	-	-	M	-	-	-	Sulfatase
IHHMCIAP_00891	1.2e-140	plsY1	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
IHHMCIAP_00892	7.51e-271	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
IHHMCIAP_00893	2.71e-167	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IHHMCIAP_00894	1.38e-170	-	-	-	-	-	-	-	-
IHHMCIAP_00895	2.41e-91	-	-	-	S	-	-	-	Oxidoreductase
IHHMCIAP_00896	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
IHHMCIAP_00897	3.64e-22	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
IHHMCIAP_00898	0.0	-	3.2.1.96, 3.5.1.28	GH73	M	ko:K01227,ko:K01447,ko:K13714,ko:K13731	ko00511,ko05100,map00511,map05100	ko00000,ko00001,ko01000	N-acetylmuramoyl-L-alanine amidase
IHHMCIAP_00899	2.71e-262	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IHHMCIAP_00900	6.35e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
IHHMCIAP_00901	3.54e-39	-	-	-	-	-	-	-	-
IHHMCIAP_00902	3.3e-158	-	-	-	-	-	-	-	-
IHHMCIAP_00903	2.42e-96	-	-	-	-	-	-	-	-
IHHMCIAP_00904	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
IHHMCIAP_00905	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
IHHMCIAP_00906	2.18e-82	-	-	-	O	-	-	-	Glutaredoxin-related protein
IHHMCIAP_00907	1.37e-290	yqjV	-	-	EGP	-	-	-	Major Facilitator Superfamily
IHHMCIAP_00908	7.92e-61	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
IHHMCIAP_00909	1.61e-44	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
IHHMCIAP_00910	6.18e-183	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IHHMCIAP_00911	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
IHHMCIAP_00912	5.46e-315	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
IHHMCIAP_00913	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
IHHMCIAP_00914	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
IHHMCIAP_00915	3e-108	-	-	-	-	-	-	-	-
IHHMCIAP_00916	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
IHHMCIAP_00917	9.06e-191	-	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IHHMCIAP_00918	1.59e-173	phnB	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IHHMCIAP_00919	2.39e-179	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
IHHMCIAP_00920	1.4e-211	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
IHHMCIAP_00921	2.22e-108	usp5	-	-	T	-	-	-	universal stress protein
IHHMCIAP_00922	3.05e-191	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
IHHMCIAP_00923	1.28e-108	-	2.7.1.200, 2.7.1.204	-	G	ko:K02773,ko:K20112	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IHHMCIAP_00924	2.59e-116	ntd	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside
IHHMCIAP_00925	6.17e-284	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IHHMCIAP_00926	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
IHHMCIAP_00927	2.65e-186	malG	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IHHMCIAP_00928	2.03e-127	malF	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IHHMCIAP_00929	4.88e-69	dexB	3.2.1.70	-	G	ko:K01215	-	ko00000,ko01000	Alpha amylase, catalytic domain protein
IHHMCIAP_00930	1.74e-23	dexB	3.2.1.70	-	G	ko:K01215	-	ko00000,ko01000	Alpha amylase, catalytic domain protein
IHHMCIAP_00931	8.91e-216	-	-	-	I	-	-	-	alpha/beta hydrolase fold
IHHMCIAP_00932	2.81e-166	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
IHHMCIAP_00933	5.27e-242	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
IHHMCIAP_00935	4.03e-263	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
IHHMCIAP_00936	5.34e-265	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
IHHMCIAP_00937	4.16e-151	crp2	-	-	K	ko:K10914,ko:K21562	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
IHHMCIAP_00938	7.92e-184	-	-	-	-	-	-	-	-
IHHMCIAP_00939	5.24e-159	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IHHMCIAP_00940	1.03e-237	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IHHMCIAP_00941	1.92e-162	-	-	-	S	-	-	-	Alpha/beta hydrolase family
IHHMCIAP_00942	2.85e-205	epsV	-	-	S	-	-	-	glycosyl transferase family 2
IHHMCIAP_00943	4.65e-208	-	-	-	S	-	-	-	Protein of unknown function (DUF1002)
IHHMCIAP_00944	2.48e-176	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IHHMCIAP_00945	1.9e-230	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
IHHMCIAP_00946	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IHHMCIAP_00947	5e-106	-	-	-	-	-	-	-	-
IHHMCIAP_00948	1.24e-169	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
IHHMCIAP_00949	7.87e-88	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
IHHMCIAP_00950	7.27e-157	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
IHHMCIAP_00951	0.0	XK27_05795	-	-	P	ko:K17073,ko:K17074	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IHHMCIAP_00952	2.81e-181	glnQ	-	-	E	ko:K17076	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IHHMCIAP_00954	4.91e-154	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
IHHMCIAP_00955	1.54e-219	-	-	-	L	-	-	-	HNH nucleases
IHHMCIAP_00956	2.02e-23	-	-	-	-	-	-	-	-
IHHMCIAP_00957	5.93e-261	ysdE	-	-	P	-	-	-	Citrate transporter
IHHMCIAP_00958	1.67e-123	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
IHHMCIAP_00959	5.3e-209	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
IHHMCIAP_00960	1.69e-193	mutR	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IHHMCIAP_00961	1.39e-283	-	-	-	S	ko:K09136	-	ko00000,ko03009	ATP diphosphatase activity
IHHMCIAP_00963	3.96e-177	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
IHHMCIAP_00964	2.22e-155	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
IHHMCIAP_00965	5.36e-219	-	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
IHHMCIAP_00966	1.06e-195	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
IHHMCIAP_00967	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
IHHMCIAP_00968	0.0	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IHHMCIAP_00969	4.27e-147	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
IHHMCIAP_00970	1.11e-25	-	-	-	L	-	-	-	transposase and inactivated derivatives, IS30 family
IHHMCIAP_00971	4.93e-49	-	-	-	L	-	-	-	transposase and inactivated derivatives, IS30 family
IHHMCIAP_00972	5.35e-81	-	-	-	S	ko:K07006	-	ko00000	Pyridoxamine 5'-phosphate oxidase
IHHMCIAP_00978	8.64e-107	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IHHMCIAP_00979	1.29e-239	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
IHHMCIAP_00980	6.41e-193	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
IHHMCIAP_00981	3.96e-183	yycI	-	-	S	-	-	-	YycH protein
IHHMCIAP_00982	0.0	yycH	-	-	S	-	-	-	YycH protein
IHHMCIAP_00983	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IHHMCIAP_00984	3.27e-170	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
IHHMCIAP_00986	2.73e-195	-	-	-	I	-	-	-	Acyl-transferase
IHHMCIAP_00987	1.25e-199	arbx	-	-	M	-	-	-	Glycosyl transferase family 8
IHHMCIAP_00988	7.03e-151	-	-	-	M	-	-	-	Glycosyl transferase family 8
IHHMCIAP_00989	2.27e-213	arbZ	-	-	I	-	-	-	Phosphate acyltransferases
IHHMCIAP_00990	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
IHHMCIAP_00991	6.06e-222	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
IHHMCIAP_00992	1.44e-191	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
IHHMCIAP_00993	3.15e-126	-	-	-	S	-	-	-	Membrane
IHHMCIAP_00994	3.87e-282	-	-	-	EGP	ko:K08196	-	ko00000,ko02000	Major Facilitator
IHHMCIAP_00995	4.37e-212	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
IHHMCIAP_00996	1.32e-220	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
IHHMCIAP_00998	2.39e-148	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
IHHMCIAP_00999	1.79e-214	cpsY	-	-	K	-	-	-	Transcriptional regulator, LysR family
IHHMCIAP_01000	1.5e-166	-	-	-	-	-	-	-	-
IHHMCIAP_01001	5.1e-29	mutS1	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
IHHMCIAP_01002	9.53e-162	mutS1	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
IHHMCIAP_01003	3.15e-192	mutS1	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
IHHMCIAP_01004	1.79e-39	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
IHHMCIAP_01005	5.19e-280	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
IHHMCIAP_01006	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
IHHMCIAP_01007	1.39e-17	-	1.3.8.1, 1.3.8.7	-	I	ko:K00248,ko:K00249,ko:K18244	ko00071,ko00280,ko00410,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map00650,map01100,map01110,map01120,map01130,map01200,map01212,map03320	ko00000,ko00001,ko00002,ko01000	Acyl-CoA dehydrogenase, C-terminal domain
IHHMCIAP_01008	3.13e-252	-	-	-	-	-	-	-	-
IHHMCIAP_01009	1.24e-230	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
IHHMCIAP_01010	2.84e-101	-	-	-	S	-	-	-	Helix-turn-helix domain
IHHMCIAP_01011	4.8e-128	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IHHMCIAP_01012	1.01e-220	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
IHHMCIAP_01013	4.26e-133	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
IHHMCIAP_01014	1.17e-96	-	-	-	K	-	-	-	LytTr DNA-binding domain
IHHMCIAP_01016	6.47e-110	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
IHHMCIAP_01017	1.04e-64	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
IHHMCIAP_01018	2.78e-55	-	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
IHHMCIAP_01019	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
IHHMCIAP_01020	7.7e-149	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
IHHMCIAP_01021	9.13e-160	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
IHHMCIAP_01022	1.35e-172	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
IHHMCIAP_01023	5.55e-54	-	-	-	-	-	-	-	-
IHHMCIAP_01025	0.0	-	3.1.4.46, 3.2.1.99	GH43	N	ko:K01126,ko:K06113	ko00564,map00564	ko00000,ko00001,ko01000	domain, Protein
IHHMCIAP_01027	3.93e-104	-	-	-	L	-	-	-	DNA synthesis involved in DNA repair
IHHMCIAP_01028	2.97e-71	-	-	-	L	-	-	-	DNA synthesis involved in DNA repair
IHHMCIAP_01029	1.01e-165	-	-	-	S	-	-	-	VanZ like family
IHHMCIAP_01030	9.37e-96	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
IHHMCIAP_01031	4.56e-104	-	-	-	S	-	-	-	VanZ like family
IHHMCIAP_01032	7.85e-12	-	-	-	M	-	-	-	NlpC/P60 family
IHHMCIAP_01033	1.28e-112	-	-	-	M	-	-	-	NlpC/P60 family
IHHMCIAP_01035	4.17e-167	-	-	-	G	-	-	-	Peptidase_C39 like family
IHHMCIAP_01036	2.67e-251	-	-	-	S	-	-	-	Acyltransferase family
IHHMCIAP_01039	5.07e-282	-	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyl transferase 4-like domain
IHHMCIAP_01040	1.06e-256	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
IHHMCIAP_01041	3.8e-228	mprF	-	-	S	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IHHMCIAP_01042	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
IHHMCIAP_01043	1.3e-40	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
IHHMCIAP_01044	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
IHHMCIAP_01045	5.92e-102	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
IHHMCIAP_01048	1.23e-275	-	-	-	S	-	-	-	FtsX-like permease family
IHHMCIAP_01049	2.2e-151	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IHHMCIAP_01051	6.88e-26	malH	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase C-terminal domain
IHHMCIAP_01052	1.74e-107	-	-	-	-	-	-	-	-
IHHMCIAP_01053	1.13e-108	ptbA	2.7.1.208	-	G	ko:K02755,ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
IHHMCIAP_01054	9.11e-118	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
IHHMCIAP_01055	1.14e-183	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
IHHMCIAP_01056	2.93e-280	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
IHHMCIAP_01057	7.59e-287	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IHHMCIAP_01058	2.66e-97	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
IHHMCIAP_01059	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
IHHMCIAP_01060	2.58e-101	cydD1	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	abc transporter atp-binding protein
IHHMCIAP_01062	4.52e-14	-	-	-	N	-	-	-	phage tail tape measure protein
IHHMCIAP_01063	1.36e-27	luxA_2	-	-	C	-	-	-	Coenzyme F420-dependent N5N10-methylene tetrahydromethanopterin reductase
IHHMCIAP_01064	5.16e-55	-	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IHHMCIAP_01065	1.76e-233	-	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Rossmann-like domain
IHHMCIAP_01066	5.63e-77	-	-	-	K	-	-	-	sequence-specific DNA binding
IHHMCIAP_01067	1.8e-69	-	-	-	-	-	-	-	-
IHHMCIAP_01068	4.49e-19	-	-	-	L	-	-	-	nuclease
IHHMCIAP_01069	2.05e-99	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
IHHMCIAP_01071	6.16e-245	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
IHHMCIAP_01072	1.29e-85	-	-	-	S	-	-	-	Core-2/I-Branching enzyme
IHHMCIAP_01073	5.51e-104	-	-	-	S	-	-	-	Core-2/I-Branching enzyme
IHHMCIAP_01074	5.38e-153	rfbP	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
IHHMCIAP_01075	5.29e-193	cps3J	-	-	M	-	-	-	Domain of unknown function (DUF4422)
IHHMCIAP_01076	2.4e-280	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
IHHMCIAP_01077	4.61e-220	-	-	-	S	ko:K07011	-	ko00000	Glycosyltransferase like family 2
IHHMCIAP_01078	1.59e-233	epsF	-	GT4	M	ko:K19424	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
IHHMCIAP_01079	2.39e-253	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
IHHMCIAP_01080	0.0	epsIIL	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
IHHMCIAP_01081	1.33e-229	licD	-	-	M	ko:K07271	-	ko00000,ko01000	LicD family
IHHMCIAP_01082	3.17e-111	tagD	2.7.7.15, 2.7.7.39	-	IM	ko:K00968,ko:K00980	ko00440,ko00564,ko01100,ko05231,map00440,map00564,map01100,map05231	ko00000,ko00001,ko00002,ko01000	Glycerol-3-phosphate cytidylyltransferase
IHHMCIAP_01083	9.64e-289	-	-	-	-	-	-	-	-
IHHMCIAP_01086	2.87e-43	bgl	3.2.1.21, 3.2.1.86	GT1	G	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	beta-glucosidase activity
IHHMCIAP_01087	6.73e-244	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
IHHMCIAP_01088	3.6e-38	scrK	2.7.1.2, 2.7.1.4	-	GK	ko:K00845,ko:K00847	ko00010,ko00051,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00051,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
IHHMCIAP_01090	5.87e-179	-	-	-	-	-	-	-	-
IHHMCIAP_01092	2.11e-108	-	-	-	K	-	-	-	DNA-templated transcription, initiation
IHHMCIAP_01094	2.5e-173	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
IHHMCIAP_01095	3.59e-213	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Sucrose glucosyltransferase
IHHMCIAP_01096	1.49e-281	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
IHHMCIAP_01097	4.77e-118	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
IHHMCIAP_01098	6.42e-229	yfdH	-	GT2	M	ko:K12999,ko:K20534	-	ko00000,ko01000,ko01003,ko01005,ko02000	Glycosyltransferase like family 2
IHHMCIAP_01099	1.64e-120	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
IHHMCIAP_01100	1.14e-186	yitS	-	-	S	-	-	-	EDD domain protein, DegV family
IHHMCIAP_01101	4.52e-115	-	-	-	T	-	-	-	EAL domain
IHHMCIAP_01102	9.22e-135	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
IHHMCIAP_01103	1.92e-161	pgm7	-	-	G	-	-	-	Phosphoglycerate mutase family
IHHMCIAP_01104	4.85e-16	-	-	-	-	-	-	-	-
IHHMCIAP_01105	5.76e-153	-	-	-	-	-	-	-	-
IHHMCIAP_01106	7.18e-57	-	-	-	-	-	-	-	-
IHHMCIAP_01107	1.32e-114	-	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	biotin transmembrane transporter activity
IHHMCIAP_01108	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
IHHMCIAP_01109	2.13e-235	ydbI	-	-	K	-	-	-	AI-2E family transporter
IHHMCIAP_01110	2.37e-222	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IHHMCIAP_01111	1.31e-44	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IHHMCIAP_01112	5.44e-230	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
IHHMCIAP_01113	1.53e-158	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
IHHMCIAP_01114	1.87e-288	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IHHMCIAP_01115	3.61e-95	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
IHHMCIAP_01116	6.26e-101	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
IHHMCIAP_01117	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
IHHMCIAP_01118	1.85e-205	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IHHMCIAP_01119	7.4e-178	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
IHHMCIAP_01120	1.28e-163	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
IHHMCIAP_01121	8.75e-160	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
IHHMCIAP_01123	1.69e-65	-	-	-	S	-	-	-	Domain of Unknown Function with PDB structure (DUF3862)
IHHMCIAP_01127	2.3e-184	-	-	-	G	-	-	-	polysaccharide deacetylase
IHHMCIAP_01128	9.05e-62	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
IHHMCIAP_01129	3.43e-213	-	1.1.1.1, 1.2.1.10, 1.2.1.87	-	C	ko:K04072,ko:K13922	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Aldehyde dehydrogenase family
IHHMCIAP_01130	9.01e-06	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
IHHMCIAP_01131	1.86e-08	-	-	-	Q	-	-	-	Methyltransferase domain
IHHMCIAP_01132	1.93e-316	-	-	-	-	-	-	-	-
IHHMCIAP_01133	7.51e-106	-	-	-	-	-	-	-	-
IHHMCIAP_01134	0.0	-	-	-	-	-	-	-	-
IHHMCIAP_01135	0.0	-	-	-	-	-	-	-	-
IHHMCIAP_01136	1.13e-223	gyaR	1.1.1.26, 1.1.1.399, 1.1.1.95	-	CH	ko:K00015,ko:K00058	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IHHMCIAP_01137	2.41e-101	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
IHHMCIAP_01138	0.0	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
IHHMCIAP_01139	0.0	XK27_09605	-	-	V	ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter transmembrane region
IHHMCIAP_01140	2.68e-67	XK27_05625	-	-	P	-	-	-	Rhodanese Homology Domain
IHHMCIAP_01141	4.92e-86	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA-DNA hybrid ribonuclease activity
IHHMCIAP_01142	3.64e-98	-	-	-	L	-	-	-	Resolvase, N-terminal
IHHMCIAP_01143	2.09e-61	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IHHMCIAP_01144	5.97e-56	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
IHHMCIAP_01145	6.36e-171	-	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD-hyrolase-like
IHHMCIAP_01147	3e-168	-	-	-	C	-	-	-	FAD binding domain
IHHMCIAP_01148	6.39e-297	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IHHMCIAP_01149	1.29e-164	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
IHHMCIAP_01150	4.16e-133	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
IHHMCIAP_01151	1.4e-164	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
IHHMCIAP_01152	3.03e-106	lytE	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
IHHMCIAP_01153	3.81e-254	idhA	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IHHMCIAP_01154	5.18e-109	lytE	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family
IHHMCIAP_01155	6.35e-126	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase homologues.
IHHMCIAP_01156	2.89e-64	-	-	-	-	-	-	-	-
IHHMCIAP_01157	0.0	-	-	-	S	-	-	-	O-antigen ligase like membrane protein
IHHMCIAP_01158	4.02e-145	-	-	-	-	-	-	-	-
IHHMCIAP_01159	3.69e-107	-	-	-	-	-	-	-	-
IHHMCIAP_01160	1.27e-110	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
IHHMCIAP_01161	4.59e-173	-	-	-	S	-	-	-	Putative threonine/serine exporter
IHHMCIAP_01162	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
IHHMCIAP_01164	1.12e-264	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
IHHMCIAP_01165	5.52e-228	-	-	-	-	-	-	-	-
IHHMCIAP_01166	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
IHHMCIAP_01167	7.83e-127	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IHHMCIAP_01168	2.2e-36	-	-	-	-	-	-	-	-
IHHMCIAP_01169	1.19e-203	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
IHHMCIAP_01170	1.98e-76	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
IHHMCIAP_01171	2.26e-115	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
IHHMCIAP_01172	8.98e-224	pepI	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
IHHMCIAP_01173	3.16e-111	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
IHHMCIAP_01174	2.09e-136	-	-	-	-	-	-	-	-
IHHMCIAP_01175	3.97e-55	-	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	dipeptidase activity
IHHMCIAP_01176	2.59e-175	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
IHHMCIAP_01177	1.52e-201	dkgB	-	-	S	-	-	-	reductase
IHHMCIAP_01179	2.67e-47	-	-	-	GK	-	-	-	ROK family
IHHMCIAP_01180	7.67e-51	-	-	-	GK	-	-	-	ROK family
IHHMCIAP_01181	2.39e-12	-	-	-	S	-	-	-	PAS domain
IHHMCIAP_01182	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
IHHMCIAP_01183	3.58e-148	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IHHMCIAP_01184	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IHHMCIAP_01185	1.01e-86	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
IHHMCIAP_01186	5.44e-315	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
IHHMCIAP_01187	1.12e-49	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IHHMCIAP_01188	1.36e-308	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
IHHMCIAP_01189	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IHHMCIAP_01190	0.000111	-	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
IHHMCIAP_01191	2.25e-70	-	-	-	-	-	-	-	-
IHHMCIAP_01192	7.9e-288	-	-	-	S	-	-	-	Membrane
IHHMCIAP_01193	3.37e-129	-	-	-	S	-	-	-	Cob(I)alamin adenosyltransferase
IHHMCIAP_01194	5.84e-123	-	-	-	S	ko:K16927	-	ko00000,ko00002,ko02000	ECF transporter, substrate-specific component
IHHMCIAP_01196	0.0	rtpR	1.17.4.2	-	F	ko:K00527	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	ribonucleoside-triphosphate reductase activity
IHHMCIAP_01197	3.46e-207	yvgN	-	-	C	-	-	-	Aldo keto reductase
IHHMCIAP_01198	2.11e-221	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
IHHMCIAP_01199	3.81e-105	-	-	-	-	-	-	-	-
IHHMCIAP_01200	1.53e-205	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
IHHMCIAP_01201	1.91e-78	-	-	-	S	-	-	-	glycolate biosynthetic process
IHHMCIAP_01202	2.73e-23	nt5e	3.1.3.18	-	L	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	haloacid dehalogenase-like hydrolase
IHHMCIAP_01203	3.57e-176	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
IHHMCIAP_01204	3.17e-87	-	-	-	L	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
IHHMCIAP_01207	2.53e-80	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
IHHMCIAP_01208	1.48e-216	potA5	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
IHHMCIAP_01209	0.0	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-type transport system involved in multi-copper enzyme maturation permease component
IHHMCIAP_01210	0.0	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
IHHMCIAP_01211	2.34e-204	XK27_10120	-	-	K	-	-	-	S-adenosyl-l-methionine hydroxide adenosyltransferase
IHHMCIAP_01212	1.32e-130	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
IHHMCIAP_01213	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IHHMCIAP_01214	2.88e-185	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
IHHMCIAP_01215	0.0	-	1.1.1.1, 1.2.1.10, 1.2.1.87	-	C	ko:K04072,ko:K13922	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Aldehyde dehydrogenase family
IHHMCIAP_01216	1.03e-111	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
IHHMCIAP_01217	9.89e-15	-	-	-	T	-	-	-	diguanylate cyclase
IHHMCIAP_01218	5.94e-141	-	-	-	T	-	-	-	EAL domain
IHHMCIAP_01220	1.29e-23	-	-	-	T	-	-	-	diguanylate cyclase
IHHMCIAP_01221	1.71e-95	-	-	-	T	-	-	-	diguanylate cyclase
IHHMCIAP_01222	4.78e-272	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
IHHMCIAP_01223	5.35e-50	-	-	-	EGP	-	-	-	Transmembrane secretion effector
IHHMCIAP_01224	8.33e-297	-	-	-	F	-	-	-	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
IHHMCIAP_01225	2.51e-120	-	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
IHHMCIAP_01226	1.3e-270	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
IHHMCIAP_01227	4.4e-65	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
IHHMCIAP_01229	6.26e-80	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
IHHMCIAP_01230	6.54e-156	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IHHMCIAP_01232	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IHHMCIAP_01233	6.58e-231	-	-	-	S	-	-	-	Conserved hypothetical protein 698
IHHMCIAP_01234	6.44e-206	-	-	-	K	-	-	-	LysR substrate binding domain
IHHMCIAP_01235	7.09e-136	-	-	-	F	-	-	-	NUDIX domain
IHHMCIAP_01236	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
IHHMCIAP_01237	6.26e-101	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IHHMCIAP_01238	1.34e-177	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IHHMCIAP_01239	5.81e-131	-	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factor activity
IHHMCIAP_01240	3.19e-45	-	-	-	-	-	-	-	-
IHHMCIAP_01241	1.73e-179	-	-	-	S	-	-	-	Alpha/beta hydrolase family
IHHMCIAP_01242	1.92e-116	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IHHMCIAP_01243	1.13e-123	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IHHMCIAP_01244	5.57e-83	dxs	2.2.1.7	-	HI	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	1-deoxy-D-xylulose-5-phosphate synthase
IHHMCIAP_01245	7.32e-28	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
IHHMCIAP_01246	3.07e-32	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
IHHMCIAP_01247	5.63e-131	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
IHHMCIAP_01248	3.27e-91	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IHHMCIAP_01249	4.45e-158	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
IHHMCIAP_01250	5.14e-245	-	-	-	S	-	-	-	Glycosyl transferase family 2
IHHMCIAP_01251	8.03e-295	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
IHHMCIAP_01252	5.15e-91	-	-	-	-	-	-	-	-
IHHMCIAP_01253	1.42e-93	-	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
IHHMCIAP_01254	1.12e-176	-	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
IHHMCIAP_01255	1.35e-108	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IHHMCIAP_01256	1.42e-71	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
IHHMCIAP_01257	3.9e-111	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
IHHMCIAP_01258	1.83e-186	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
IHHMCIAP_01259	2.65e-55	-	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
IHHMCIAP_01261	5.18e-34	-	5.3.1.6	-	G	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose/Galactose Isomerase
IHHMCIAP_01262	1.49e-54	-	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
IHHMCIAP_01263	5.84e-274	pbpX	-	-	V	-	-	-	Beta-lactamase
IHHMCIAP_01264	7.54e-264	pbpX1	-	-	V	-	-	-	Beta-lactamase
IHHMCIAP_01265	9.36e-20	-	-	-	L	ko:K07483,ko:K07497	-	ko00000	Helix-turn-helix domain
IHHMCIAP_01266	1.92e-60	-	-	-	-	-	-	-	-
IHHMCIAP_01267	9.29e-200	-	-	-	-	-	-	-	-
IHHMCIAP_01268	2.31e-117	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IHHMCIAP_01269	1.79e-144	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
IHHMCIAP_01270	1.93e-117	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
IHHMCIAP_01271	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IHHMCIAP_01272	1.9e-68	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IHHMCIAP_01273	3.6e-139	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IHHMCIAP_01274	2.21e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
IHHMCIAP_01275	2.32e-146	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IHHMCIAP_01276	6.39e-71	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
IHHMCIAP_01277	4.02e-204	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
IHHMCIAP_01278	2.21e-72	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
IHHMCIAP_01279	4.53e-204	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IHHMCIAP_01280	5.06e-182	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
IHHMCIAP_01281	5.44e-116	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
IHHMCIAP_01282	5.82e-163	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
IHHMCIAP_01283	2.61e-123	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
IHHMCIAP_01284	4.09e-248	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IHHMCIAP_01285	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
IHHMCIAP_01286	1.23e-158	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IHHMCIAP_01287	3.69e-59	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IHHMCIAP_01288	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
IHHMCIAP_01289	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IHHMCIAP_01290	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IHHMCIAP_01291	2.85e-135	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
IHHMCIAP_01292	1.02e-236	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
IHHMCIAP_01293	5.99e-71	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
IHHMCIAP_01294	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IHHMCIAP_01295	2e-263	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IHHMCIAP_01296	1.89e-228	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
IHHMCIAP_01297	4.29e-295	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
IHHMCIAP_01298	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IHHMCIAP_01299	3.09e-56	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
IHHMCIAP_01300	6.34e-94	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IHHMCIAP_01301	1.92e-67	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
IHHMCIAP_01302	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
IHHMCIAP_01303	3.11e-71	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
IHHMCIAP_01304	1.01e-87	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
IHHMCIAP_01305	1.46e-146	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IHHMCIAP_01306	3.99e-196	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
IHHMCIAP_01307	1.1e-27	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IHHMCIAP_01308	4.86e-59	-	-	-	-	-	-	-	-
IHHMCIAP_01309	5.67e-34	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
IHHMCIAP_01311	3.94e-273	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
IHHMCIAP_01312	2.14e-232	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
IHHMCIAP_01313	2.89e-77	-	-	-	-	-	-	-	-
IHHMCIAP_01314	0.0	sasH	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01081,ko:K01119,ko:K07004,ko:K08693,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
IHHMCIAP_01315	7.82e-114	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
IHHMCIAP_01316	3.84e-185	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
IHHMCIAP_01317	4.03e-137	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
IHHMCIAP_01318	5.45e-153	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
IHHMCIAP_01319	1.46e-236	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
IHHMCIAP_01320	3.71e-235	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IHHMCIAP_01321	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
IHHMCIAP_01322	2.12e-113	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
IHHMCIAP_01323	1.82e-277	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
IHHMCIAP_01324	1.42e-218	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IHHMCIAP_01325	1.56e-181	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
IHHMCIAP_01326	2.32e-280	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
IHHMCIAP_01327	2.36e-142	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IHHMCIAP_01328	2.05e-196	-	-	-	S	-	-	-	Protein of unknown function (DUF3298)
IHHMCIAP_01329	1.13e-127	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70 region 2
IHHMCIAP_01330	0.0	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IHHMCIAP_01331	1.95e-119	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
IHHMCIAP_01332	9.93e-136	-	-	-	S	-	-	-	SNARE associated Golgi protein
IHHMCIAP_01333	1.12e-193	-	-	-	I	-	-	-	alpha/beta hydrolase fold
IHHMCIAP_01334	2.83e-202	plcR	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
IHHMCIAP_01335	1.32e-122	-	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside 2-deoxyribosyltransferase
IHHMCIAP_01336	3.44e-167	-	-	-	F	-	-	-	glutamine amidotransferase
IHHMCIAP_01337	7.47e-21	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
IHHMCIAP_01338	1.06e-37	tnp2	-	-	L	-	-	-	PFAM Transposase, IS204 IS1001 IS1096 IS1165
IHHMCIAP_01339	4.51e-65	pinR1	-	-	L	-	-	-	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
IHHMCIAP_01340	1.56e-203	yicL	-	-	EG	-	-	-	EamA-like transporter family
IHHMCIAP_01341	7.72e-177	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
IHHMCIAP_01342	1.1e-190	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
IHHMCIAP_01343	2.75e-212	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
IHHMCIAP_01344	1.66e-304	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IHHMCIAP_01345	6.43e-195	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
IHHMCIAP_01346	2.13e-116	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
IHHMCIAP_01347	2.22e-182	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
IHHMCIAP_01348	2.48e-96	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
IHHMCIAP_01349	1.05e-201	loxD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
IHHMCIAP_01350	7.19e-118	loxD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
IHHMCIAP_01351	7.25e-240	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IHHMCIAP_01352	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
IHHMCIAP_01353	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
IHHMCIAP_01354	4.95e-35	-	-	-	K	ko:K02529	-	ko00000,ko03000	purine nucleotide biosynthetic process
IHHMCIAP_01355	4.73e-138	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
IHHMCIAP_01372	1.98e-107	-	-	-	E	ko:K03758	-	ko00000,ko02000	amino acid
IHHMCIAP_01373	2.35e-133	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
IHHMCIAP_01374	4.34e-63	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
IHHMCIAP_01375	4.05e-09	XK27_07210	-	-	S	-	-	-	B3 4 domain
IHHMCIAP_01376	3.05e-172	-	-	-	S	-	-	-	amidohydrolase
IHHMCIAP_01377	0.000745	-	-	-	S	-	-	-	Amidohydrolase family
IHHMCIAP_01378	1.14e-309	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
IHHMCIAP_01379	9.31e-71	-	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
IHHMCIAP_01381	2.25e-206	-	-	-	J	-	-	-	Methyltransferase
IHHMCIAP_01382	8.57e-101	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Aluminium induced protein
IHHMCIAP_01383	2.11e-231	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Aluminium induced protein
IHHMCIAP_01388	6.64e-187	-	-	-	F	-	-	-	NUDIX domain
IHHMCIAP_01389	1.9e-56	-	-	-	L	-	-	-	Membrane
IHHMCIAP_01390	1.07e-144	-	-	-	-	-	-	-	-
IHHMCIAP_01391	4.64e-139	pncA	-	-	Q	-	-	-	Isochorismatase family
IHHMCIAP_01392	1.14e-34	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
IHHMCIAP_01393	2.42e-36	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IHHMCIAP_01394	3.76e-72	-	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	MafB19-like deaminase
IHHMCIAP_01399	3.36e-111	-	-	-	L	-	-	-	COG3547 Transposase and inactivated derivatives
IHHMCIAP_01400	2.79e-162	gntR1	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
IHHMCIAP_01401	8.02e-255	-	-	-	-	-	-	-	-
IHHMCIAP_01402	6.54e-273	-	-	-	-	-	-	-	-
IHHMCIAP_01403	1.27e-73	oppA2	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
IHHMCIAP_01406	3.07e-225	pfoSR	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
IHHMCIAP_01407	4.22e-286	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
IHHMCIAP_01410	1.8e-119	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
IHHMCIAP_01411	2.84e-63	-	-	-	EGP	-	-	-	Major Facilitator
IHHMCIAP_01412	4.19e-64	-	-	-	EGP	-	-	-	Major Facilitator
IHHMCIAP_01413	1.59e-155	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
IHHMCIAP_01415	1.76e-90	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
IHHMCIAP_01416	1.1e-178	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
IHHMCIAP_01417	5.07e-61	-	-	-	-	-	-	-	-
IHHMCIAP_01418	1.79e-30	-	-	-	-	-	-	-	-
IHHMCIAP_01419	9.68e-86	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
IHHMCIAP_01420	1.54e-101	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IHHMCIAP_01421	8.77e-194	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
IHHMCIAP_01422	1.28e-183	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IHHMCIAP_01423	2.44e-208	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IHHMCIAP_01424	5.7e-200	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IHHMCIAP_01425	1.91e-81	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
IHHMCIAP_01426	2.66e-220	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IHHMCIAP_01427	6.6e-83	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IHHMCIAP_01428	5.08e-74	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IHHMCIAP_01429	3.13e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IHHMCIAP_01430	3.43e-155	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
IHHMCIAP_01431	5.33e-303	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
IHHMCIAP_01432	5.15e-95	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
IHHMCIAP_01433	1.1e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
IHHMCIAP_01434	4.52e-112	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IHHMCIAP_01435	1.55e-74	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IHHMCIAP_01436	2.92e-120	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IHHMCIAP_01437	9.28e-89	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IHHMCIAP_01438	1.75e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IHHMCIAP_01439	1.38e-45	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IHHMCIAP_01440	1.73e-77	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IHHMCIAP_01441	1.34e-56	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IHHMCIAP_01442	9.34e-34	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
IHHMCIAP_01443	8.89e-101	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IHHMCIAP_01444	2.31e-156	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IHHMCIAP_01445	3.7e-72	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IHHMCIAP_01446	1.79e-60	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IHHMCIAP_01447	2.82e-198	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IHHMCIAP_01448	1.72e-59	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
IHHMCIAP_01449	6.65e-138	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
IHHMCIAP_01450	3.42e-142	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IHHMCIAP_01451	1.55e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
IHHMCIAP_01452	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IHHMCIAP_01453	6.89e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
IHHMCIAP_01454	2.96e-91	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IHHMCIAP_01455	3.01e-11	-	-	-	Q	-	-	-	phosphatase activity
IHHMCIAP_01456	1.83e-09	-	-	-	S	-	-	-	hydrolase
IHHMCIAP_01458	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IHHMCIAP_01459	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IHHMCIAP_01462	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
IHHMCIAP_01463	9.11e-106	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
IHHMCIAP_01467	3.88e-140	XK27_00160	-	-	S	-	-	-	Domain of unknown function (DUF5052)
IHHMCIAP_01468	3.55e-278	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
IHHMCIAP_01469	4.18e-31	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	o-acetylhomoserine
IHHMCIAP_01471	3.99e-180	-	-	-	T	ko:K03320	-	ko00000,ko02000	GGDEF domain
IHHMCIAP_01473	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
IHHMCIAP_01474	1.09e-251	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IHHMCIAP_01475	0.0	yqjE	3.4.11.14, 3.4.11.4	-	E	ko:K01258,ko:K01263	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
IHHMCIAP_01476	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
IHHMCIAP_01477	2.85e-210	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IHHMCIAP_01478	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IHHMCIAP_01479	0.0	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
IHHMCIAP_01480	4.32e-80	-	-	-	J	ko:K07571	-	ko00000	S1 RNA binding domain
IHHMCIAP_01481	4.01e-78	-	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
IHHMCIAP_01482	1.48e-45	yabO	-	-	J	-	-	-	S4 domain protein
IHHMCIAP_01483	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IHHMCIAP_01484	5.2e-132	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
IHHMCIAP_01485	9.02e-163	-	-	-	S	-	-	-	(CBS) domain
IHHMCIAP_01486	6.86e-278	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IHHMCIAP_01487	3.58e-93	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
IHHMCIAP_01488	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
IHHMCIAP_01489	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
IHHMCIAP_01490	3.27e-55	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
IHHMCIAP_01491	1.26e-306	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IHHMCIAP_01492	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
IHHMCIAP_01493	3.67e-88	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
IHHMCIAP_01494	1.73e-84	-	-	-	S	-	-	-	Domain of unknown function (DUF1934)
IHHMCIAP_01495	0.0	-	-	-	S	ko:K06885	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
IHHMCIAP_01496	1.27e-225	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IHHMCIAP_01497	6.16e-62	-	-	-	-	-	-	-	-
IHHMCIAP_01498	0.0	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IHHMCIAP_01499	3.03e-192	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
IHHMCIAP_01500	4.13e-51	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
IHHMCIAP_01501	1.57e-204	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
IHHMCIAP_01502	3.34e-126	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IHHMCIAP_01503	5.49e-191	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
IHHMCIAP_01504	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IHHMCIAP_01505	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
IHHMCIAP_01506	7.13e-134	-	-	-	S	ko:K06872	-	ko00000	TPM domain
IHHMCIAP_01507	2.79e-117	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	MafB19-like deaminase
IHHMCIAP_01508	9.25e-247	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
IHHMCIAP_01510	2.91e-154	-	-	-	-	-	-	-	-
IHHMCIAP_01511	3.12e-06	-	-	-	KLT	-	-	-	Protein tyrosine kinase
IHHMCIAP_01512	6.61e-167	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IHHMCIAP_01513	7.86e-174	-	-	-	V	-	-	-	ABC-2 type transporter
IHHMCIAP_01514	3.2e-150	-	-	-	E	-	-	-	peptidase
IHHMCIAP_01516	3.88e-55	-	-	-	S	-	-	-	Enterocin A Immunity
IHHMCIAP_01517	2.58e-296	-	-	-	L	-	-	-	Transposase
IHHMCIAP_01518	2.53e-228	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
IHHMCIAP_01519	3.35e-139	-	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
IHHMCIAP_01520	5.43e-97	-	-	-	-	-	-	-	-
IHHMCIAP_01532	8.53e-110	ykuL	-	-	S	-	-	-	(CBS) domain
IHHMCIAP_01533	0.0	cadA	-	-	P	-	-	-	P-type ATPase
IHHMCIAP_01534	4.84e-258	napA	-	-	P	-	-	-	Sodium/hydrogen exchanger family
IHHMCIAP_01535	7.53e-158	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
IHHMCIAP_01536	2.3e-255	-	-	-	S	-	-	-	DUF218 domain
IHHMCIAP_01537	1.81e-251	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein PnrA-like
IHHMCIAP_01539	1.64e-86	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
IHHMCIAP_01540	9.88e-240	pkn2	-	-	KLT	-	-	-	Protein tyrosine kinase
IHHMCIAP_01541	6.32e-96	-	-	-	S	-	-	-	Domain of unknown function (DUF4352)
IHHMCIAP_01542	9.28e-250	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein PnrA-like
IHHMCIAP_01543	2.55e-90	-	-	-	S	-	-	-	SLAP domain
IHHMCIAP_01544	0.0	-	-	-	L	-	-	-	Transposase DDE domain
IHHMCIAP_01545	5.29e-177	-	-	-	E	ko:K02054	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IHHMCIAP_01546	5.54e-172	potC3	-	-	E	ko:K02053	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IHHMCIAP_01547	2.17e-242	potA11	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K02052,ko:K11072	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
IHHMCIAP_01548	2.73e-79	-	-	-	P	ko:K02055	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
IHHMCIAP_01549	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Adenine deaminase C-terminal domain
IHHMCIAP_01550	1.82e-254	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein PnrA-like
IHHMCIAP_01551	0.0	mglA	3.6.3.17	-	S	ko:K02056,ko:K06400	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
IHHMCIAP_01552	8.77e-262	mglC	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
IHHMCIAP_01553	2.98e-220	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
IHHMCIAP_01554	4.37e-26	-	-	-	EGP	-	-	-	Major Facilitator
IHHMCIAP_01556	1.78e-202	-	-	-	S	-	-	-	Aldo/keto reductase family
IHHMCIAP_01557	1.05e-162	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IHHMCIAP_01559	3.02e-19	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
IHHMCIAP_01561	1.73e-212	ybfG	-	-	M	-	-	-	peptidoglycan-binding domain-containing protein
IHHMCIAP_01562	9.3e-53	-	-	-	-	-	-	-	-
IHHMCIAP_01563	6.66e-159	dak	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
IHHMCIAP_01564	8.05e-166	dgk2	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
IHHMCIAP_01565	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IHHMCIAP_01566	8.7e-178	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IHHMCIAP_01567	1.89e-294	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
IHHMCIAP_01568	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
IHHMCIAP_01569	2.56e-20	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
IHHMCIAP_01570	3.05e-91	-	-	-	-	-	-	-	-
IHHMCIAP_01571	8.93e-118	-	-	-	-	-	-	-	-
IHHMCIAP_01572	5.64e-61	-	-	-	-	-	-	-	-
IHHMCIAP_01573	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IHHMCIAP_01574	0.0	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
IHHMCIAP_01575	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
IHHMCIAP_01576	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IHHMCIAP_01577	1.28e-195	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IHHMCIAP_01578	1.48e-82	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
IHHMCIAP_01579	6.59e-23	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
IHHMCIAP_01580	1.7e-313	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IHHMCIAP_01581	9.76e-257	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
IHHMCIAP_01582	2.22e-50	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
IHHMCIAP_01583	2.02e-268	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IHHMCIAP_01584	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IHHMCIAP_01585	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IHHMCIAP_01586	1.21e-63	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
IHHMCIAP_01587	1.79e-126	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IHHMCIAP_01588	1.61e-48	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IHHMCIAP_01589	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
IHHMCIAP_01590	6.68e-98	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
IHHMCIAP_01591	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
IHHMCIAP_01592	3.46e-287	-	-	-	S	-	-	-	Protein of unknown function (DUF2974)
IHHMCIAP_01593	0.0	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
IHHMCIAP_01594	4.46e-90	-	-	-	-	-	-	-	-
IHHMCIAP_01596	3.24e-157	-	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
IHHMCIAP_01598	5.4e-90	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
IHHMCIAP_01599	3.22e-105	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
IHHMCIAP_01600	6.57e-179	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
IHHMCIAP_01601	1.91e-243	pltK	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
IHHMCIAP_01603	3.6e-35	-	-	-	-	-	-	-	-
IHHMCIAP_01604	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K06147,ko:K11085,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
IHHMCIAP_01605	0.0	-	-	-	KLT	-	-	-	Protein kinase domain
IHHMCIAP_01606	6.96e-30	-	-	-	-	-	-	-	-
IHHMCIAP_01608	2.7e-145	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IHHMCIAP_01609	5.36e-171	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
IHHMCIAP_01611	0.0	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
IHHMCIAP_01612	2.85e-15	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
IHHMCIAP_01613	8.13e-38	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
IHHMCIAP_01614	3.56e-196	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
IHHMCIAP_01615	1.59e-117	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
IHHMCIAP_01616	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
IHHMCIAP_01617	2.18e-132	-	-	-	T	-	-	-	integral membrane protein
IHHMCIAP_01618	1.33e-110	-	-	-	S	-	-	-	YcxB-like protein
IHHMCIAP_01619	1.89e-95	ywnA	-	-	K	-	-	-	Transcriptional regulator
IHHMCIAP_01620	2.58e-11	qorB	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	epimerase
IHHMCIAP_01621	1.17e-71	qorB	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NmrA-like family
IHHMCIAP_01622	3.62e-38	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
IHHMCIAP_01624	5.32e-85	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
IHHMCIAP_01633	1.29e-31	-	-	-	L	-	-	-	DDE superfamily endonuclease
IHHMCIAP_01634	1.34e-36	-	-	-	-	-	-	-	-
IHHMCIAP_01635	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
IHHMCIAP_01636	8.64e-312	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
IHHMCIAP_01637	2.42e-97	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
IHHMCIAP_01638	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IHHMCIAP_01639	1.32e-221	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
IHHMCIAP_01640	1.16e-115	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IHHMCIAP_01641	1.04e-306	-	-	-	S	-	-	-	Putative threonine/serine exporter
IHHMCIAP_01642	6.16e-282	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
IHHMCIAP_01643	2.69e-274	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
IHHMCIAP_01644	4.76e-248	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
IHHMCIAP_01645	4.8e-64	-	-	-	S	-	-	-	CRISPR-associated protein (Cas_Csn2)
IHHMCIAP_01646	2.7e-51	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IHHMCIAP_01647	5.57e-165	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IHHMCIAP_01648	0.0	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
IHHMCIAP_01649	4.82e-293	sptS	-	-	T	-	-	-	Histidine kinase
IHHMCIAP_01650	9.36e-151	dltr	-	-	K	-	-	-	response regulator
IHHMCIAP_01651	5.97e-145	-	-	-	T	-	-	-	Region found in RelA / SpoT proteins
IHHMCIAP_01652	2.46e-13	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
IHHMCIAP_01654	3.77e-27	-	-	-	-	-	-	-	-
IHHMCIAP_01657	1.18e-248	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
IHHMCIAP_01658	3.63e-91	-	-	-	-	-	-	-	-
IHHMCIAP_01659	0.0	-	-	-	I	-	-	-	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IHHMCIAP_01660	9.11e-36	-	-	-	-	-	-	-	-
IHHMCIAP_01661	2.47e-145	-	-	-	K	ko:K13928	-	ko00000,ko03000	DNA-binding transcription factor activity
IHHMCIAP_01662	3.17e-12	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
IHHMCIAP_01663	4.08e-219	-	-	-	K	-	-	-	LysR substrate binding domain
IHHMCIAP_01664	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
IHHMCIAP_01665	1.68e-292	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
IHHMCIAP_01666	5.57e-55	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
IHHMCIAP_01667	2.29e-315	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
IHHMCIAP_01668	5.05e-279	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
IHHMCIAP_01669	1.22e-139	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
IHHMCIAP_01670	5.23e-06	mltD	-	-	M	ko:K08307	-	ko00000,ko01000,ko01011	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
IHHMCIAP_01671	9.54e-150	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IHHMCIAP_01672	3.39e-166	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
IHHMCIAP_01673	1.77e-135	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IHHMCIAP_01674	2.77e-165	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IHHMCIAP_01675	2.22e-82	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IHHMCIAP_01676	1.26e-211	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
IHHMCIAP_01677	4.38e-209	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
IHHMCIAP_01678	1.14e-120	-	-	-	I	-	-	-	Acyltransferase family
IHHMCIAP_01680	1.16e-50	ssuB	-	-	P	ko:K02049,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	anion transmembrane transporter activity
IHHMCIAP_01681	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
IHHMCIAP_01682	3.98e-230	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
IHHMCIAP_01683	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
IHHMCIAP_01684	2.87e-39	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
IHHMCIAP_01685	3.11e-95	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IHHMCIAP_01686	4.1e-100	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IHHMCIAP_01687	5.8e-98	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IHHMCIAP_01688	2.71e-72	-	-	-	K	ko:K03492	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
IHHMCIAP_01689	1.01e-19	-	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA
IHHMCIAP_01690	1.37e-128	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
IHHMCIAP_01692	4.23e-61	-	-	-	-	-	-	-	-
IHHMCIAP_01693	0.0	-	-	-	L	-	-	-	SNF2 family N-terminal domain
IHHMCIAP_01694	0.0	yfkN	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
IHHMCIAP_01695	3.88e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
IHHMCIAP_01696	7.34e-178	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
IHHMCIAP_01697	4.62e-224	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
IHHMCIAP_01698	0.0	oatA	-	-	I	-	-	-	Acyltransferase
IHHMCIAP_01699	6.47e-298	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IHHMCIAP_01700	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
IHHMCIAP_01701	6.15e-235	iunH	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	inosine-uridine preferring nucleoside hydrolase
IHHMCIAP_01702	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
IHHMCIAP_01703	3.95e-224	gyaR	1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81	-	CH	ko:K00015,ko:K00090	ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IHHMCIAP_01704	8.14e-265	-	-	-	S	ko:K07045	-	ko00000	Amidohydrolase
IHHMCIAP_01705	2.34e-283	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IHHMCIAP_01706	6.58e-101	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
IHHMCIAP_01707	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
IHHMCIAP_01708	3.61e-214	yvbU	-	-	K	-	-	-	LysR substrate binding domain
IHHMCIAP_01709	3.43e-290	-	-	-	EK	-	-	-	Aminotransferase, class I
IHHMCIAP_01710	2.88e-92	-	-	-	E	-	-	-	Methionine synthase
IHHMCIAP_01712	6.85e-33	-	-	-	L	-	-	-	Transposase
IHHMCIAP_01713	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
IHHMCIAP_01714	3.27e-130	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
IHHMCIAP_01715	5.07e-74	-	-	-	KT	-	-	-	response to antibiotic
IHHMCIAP_01716	2.09e-173	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
IHHMCIAP_01717	6.92e-155	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
IHHMCIAP_01718	1.01e-185	-	3.1.3.102, 3.1.3.104, 3.1.3.23	-	G	ko:K07757,ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
IHHMCIAP_01719	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
IHHMCIAP_01720	1.41e-211	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
IHHMCIAP_01721	3.02e-174	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
IHHMCIAP_01722	3.86e-186	racD	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
IHHMCIAP_01723	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IHHMCIAP_01724	4.19e-283	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
IHHMCIAP_01725	3.03e-159	vanR	-	-	K	-	-	-	response regulator
IHHMCIAP_01726	0.0	ndvA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
IHHMCIAP_01727	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter, ATP-binding protein
IHHMCIAP_01728	1.61e-177	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
IHHMCIAP_01729	6.88e-257	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
IHHMCIAP_01730	1.1e-59	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
IHHMCIAP_01731	4.14e-200	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
IHHMCIAP_01732	2.37e-176	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
IHHMCIAP_01733	1.54e-184	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
IHHMCIAP_01734	3.68e-170	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
IHHMCIAP_01735	5.62e-146	-	-	-	L	-	-	-	Resolvase, N terminal domain
IHHMCIAP_01736	0.0	-	-	-	L	-	-	-	Putative transposase DNA-binding domain
IHHMCIAP_01737	2.13e-112	cvpA	-	-	S	-	-	-	Colicin V production protein
IHHMCIAP_01738	3.87e-237	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
IHHMCIAP_01739	5.03e-183	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
IHHMCIAP_01740	5e-124	azr	1.5.1.36	-	S	ko:K22394	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
IHHMCIAP_01741	2.92e-126	azo1	1.5.1.36, 1.7.1.6	-	S	ko:K03206,ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
IHHMCIAP_01742	4.76e-127	-	-	-	K	-	-	-	WHG domain
IHHMCIAP_01743	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
IHHMCIAP_01745	6.6e-150	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
IHHMCIAP_01746	3.24e-138	-	-	-	-	-	-	-	-
IHHMCIAP_01748	1.79e-178	-	-	-	-	-	-	-	-
IHHMCIAP_01749	9.24e-114	-	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
IHHMCIAP_01750	2.06e-14	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
IHHMCIAP_01751	1.33e-87	-	-	-	S	-	-	-	pyridoxamine 5-phosphate
IHHMCIAP_01752	2.77e-220	-	-	-	K	-	-	-	WYL domain
IHHMCIAP_01753	1.68e-154	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IHHMCIAP_01754	1.76e-236	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
IHHMCIAP_01755	9.21e-115	-	-	-	K	-	-	-	transcriptional regulator (TetR family)
IHHMCIAP_01756	6.45e-87	glcD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
IHHMCIAP_01757	1.06e-63	glcD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
IHHMCIAP_01758	7.19e-180	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
IHHMCIAP_01759	4.89e-152	-	-	-	-	-	-	-	-
IHHMCIAP_01760	5.15e-290	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
IHHMCIAP_01762	6.27e-40	drgA	-	-	C	-	-	-	coenzyme F420-1:gamma-L-glutamate ligase activity
IHHMCIAP_01763	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
IHHMCIAP_01764	8.02e-49	lysM	-	-	M	-	-	-	LysM domain
IHHMCIAP_01765	7.07e-222	citI	-	-	K	-	-	-	Putative sugar-binding domain
IHHMCIAP_01766	0.0	-	-	-	M	ko:K08659	-	ko00000,ko01000,ko01002	Peptidase family C69
IHHMCIAP_01768	0.0	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
IHHMCIAP_01769	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
IHHMCIAP_01771	4.25e-197	-	-	-	-	-	-	-	-
IHHMCIAP_01772	2.88e-47	-	-	-	-	-	-	-	-
IHHMCIAP_01773	7.6e-118	ymdB	-	-	S	-	-	-	Macro domain protein
IHHMCIAP_01774	1.59e-186	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
IHHMCIAP_01775	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
IHHMCIAP_01776	0.0	-	-	-	KLT	-	-	-	serine threonine protein kinase
IHHMCIAP_01777	2.82e-185	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
IHHMCIAP_01778	2.3e-184	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IHHMCIAP_01779	1.87e-33	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IHHMCIAP_01780	3.87e-168	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
IHHMCIAP_01781	7.46e-50	-	-	-	-	-	-	-	-
IHHMCIAP_01782	0.0	clpL	-	-	O	ko:K04086	-	ko00000,ko03110	C-terminal, D2-small domain, of ClpB protein
IHHMCIAP_01783	1.79e-78	-	-	-	T	-	-	-	diguanylate cyclase
IHHMCIAP_01784	1.56e-55	-	-	-	T	-	-	-	diguanylate cyclase
IHHMCIAP_01785	8.49e-83	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
IHHMCIAP_01786	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
IHHMCIAP_01787	2.01e-267	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
IHHMCIAP_01788	1.75e-314	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
IHHMCIAP_01789	8.08e-234	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
IHHMCIAP_01790	2.49e-123	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IHHMCIAP_01791	3.74e-213	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
IHHMCIAP_01794	3.26e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
IHHMCIAP_01795	1.67e-74	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
IHHMCIAP_01796	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
IHHMCIAP_01797	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IHHMCIAP_01798	3.56e-234	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
IHHMCIAP_01799	1.31e-48	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IHHMCIAP_01800	3.75e-242	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IHHMCIAP_01801	3.53e-228	oppF	-	-	P	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IHHMCIAP_01802	2.21e-227	oppB	-	-	P	ko:K02033,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IHHMCIAP_01803	4.18e-208	oppC5	-	-	P	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IHHMCIAP_01804	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
IHHMCIAP_01805	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
IHHMCIAP_01806	2.5e-164	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
IHHMCIAP_01807	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
IHHMCIAP_01808	1.71e-219	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
IHHMCIAP_01809	4.93e-09	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
IHHMCIAP_01810	7.82e-23	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
IHHMCIAP_01811	1.5e-115	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
IHHMCIAP_01812	1.36e-96	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
IHHMCIAP_01813	2.27e-71	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
IHHMCIAP_01814	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IHHMCIAP_01815	3.93e-59	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
IHHMCIAP_01816	4.06e-118	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IHHMCIAP_01817	2.41e-178	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
IHHMCIAP_01819	0.0	snf	-	-	KL	-	-	-	domain protein
IHHMCIAP_01820	4.71e-74	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
IHHMCIAP_01821	0.0	XK27_00340	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
IHHMCIAP_01822	0.0	-	-	-	S	-	-	-	TerB-C domain
IHHMCIAP_01823	3.4e-315	-	-	-	P	-	-	-	P-loop Domain of unknown function (DUF2791)
IHHMCIAP_01824	0.0	-	-	-	L	ko:K03724	-	ko00000,ko01000,ko03400	DEAD DEAH box helicase
IHHMCIAP_01825	1.19e-124	-	-	-	-	-	-	-	-
IHHMCIAP_01826	1.44e-198	glnH	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
IHHMCIAP_01827	4.13e-193	-	-	-	U	ko:K05340	-	ko00000,ko02000	ribose uptake protein RbsU
IHHMCIAP_01828	2.53e-147	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IHHMCIAP_01829	1.5e-44	ynzC	-	-	S	-	-	-	UPF0291 protein
IHHMCIAP_01830	1.55e-42	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
IHHMCIAP_01831	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IHHMCIAP_01832	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IHHMCIAP_01833	1.05e-93	pheB	5.4.99.5	-	S	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the UPF0735 family
IHHMCIAP_01834	1.13e-270	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
IHHMCIAP_01835	0.0	-	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
IHHMCIAP_01836	5.05e-233	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IHHMCIAP_01837	2.26e-149	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
IHHMCIAP_01838	1.41e-243	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
IHHMCIAP_01839	1.49e-176	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
IHHMCIAP_01840	8.09e-237	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IHHMCIAP_01841	5.02e-169	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
IHHMCIAP_01842	2.75e-118	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
IHHMCIAP_01843	3.99e-176	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IHHMCIAP_01844	1.97e-187	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
IHHMCIAP_01845	5.84e-292	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
IHHMCIAP_01846	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
IHHMCIAP_01847	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IHHMCIAP_01848	1.01e-109	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
IHHMCIAP_01849	9.15e-263	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
IHHMCIAP_01850	1.03e-57	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
IHHMCIAP_01851	2.5e-57	ylxQ	-	-	J	-	-	-	ribosomal protein
IHHMCIAP_01852	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IHHMCIAP_01853	2.57e-78	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IHHMCIAP_01854	1.6e-214	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IHHMCIAP_01855	2.12e-70	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Bacterial transferase hexapeptide (six repeats)
IHHMCIAP_01856	2.93e-279	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
IHHMCIAP_01857	3.48e-216	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
IHHMCIAP_01858	9.31e-44	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
IHHMCIAP_01859	2.49e-114	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
IHHMCIAP_01860	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IHHMCIAP_01861	3.25e-35	-	-	-	L	-	-	-	Transposase
IHHMCIAP_01863	4.8e-128	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
IHHMCIAP_01864	1.82e-227	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
IHHMCIAP_01865	6.5e-246	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
IHHMCIAP_01866	1.04e-109	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IHHMCIAP_01867	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
IHHMCIAP_01868	5.57e-237	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
IHHMCIAP_01869	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
IHHMCIAP_01870	3.97e-93	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
IHHMCIAP_01871	6.04e-43	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
IHHMCIAP_01872	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
IHHMCIAP_01873	2.82e-122	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IHHMCIAP_01874	5.47e-66	-	-	-	K	-	-	-	DNA-binding transcription factor activity
IHHMCIAP_01875	4.47e-199	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
IHHMCIAP_01876	1.39e-257	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
IHHMCIAP_01877	8.77e-245	-	-	-	S	-	-	-	AI-2E family transporter
IHHMCIAP_01878	1.59e-66	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
IHHMCIAP_01879	1.55e-91	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
IHHMCIAP_01880	0.0	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
IHHMCIAP_01881	4.37e-205	lysR5	-	-	K	-	-	-	LysR substrate binding domain
IHHMCIAP_01882	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
IHHMCIAP_01883	2.3e-172	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IHHMCIAP_01884	6.92e-134	-	-	-	S	-	-	-	Protein of unknown function (DUF4230)
IHHMCIAP_01885	2.82e-256	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF898)
IHHMCIAP_01886	1.09e-70	-	-	-	S	-	-	-	Protein of unknown function (DUF2752)
IHHMCIAP_01887	9.3e-310	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IHHMCIAP_01888	1.06e-193	-	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
IHHMCIAP_01889	1.52e-129	-	-	-	I	-	-	-	PAP2 superfamily
IHHMCIAP_01890	5.52e-203	-	-	-	-	-	-	-	-
IHHMCIAP_01891	1.79e-212	-	-	-	K	-	-	-	LysR substrate binding domain
IHHMCIAP_01892	0.0	yfiB1	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter, ATP-binding protein
IHHMCIAP_01893	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
IHHMCIAP_01897	5.15e-216	XK27_10395	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IHHMCIAP_01898	1.02e-280	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
IHHMCIAP_01899	4.64e-150	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
IHHMCIAP_01900	3.72e-200	degV3	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
IHHMCIAP_01901	9.85e-49	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
IHHMCIAP_01902	4.39e-210	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IHHMCIAP_01903	1.88e-176	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IHHMCIAP_01904	1.02e-196	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
IHHMCIAP_01905	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IHHMCIAP_01906	9.47e-317	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
IHHMCIAP_01907	2.35e-210	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Phage integrase, N-terminal SAM-like domain
IHHMCIAP_01908	7.14e-117	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
IHHMCIAP_01909	1.58e-314	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
IHHMCIAP_01910	1.13e-223	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
IHHMCIAP_01913	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
IHHMCIAP_01914	1.47e-288	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
IHHMCIAP_01915	1.06e-10	secY2	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	SecY translocase
IHHMCIAP_01917	1.71e-207	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IHHMCIAP_01919	1.32e-192	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
IHHMCIAP_01920	4.83e-30	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
IHHMCIAP_01921	2.36e-220	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
IHHMCIAP_01922	2.52e-129	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IHHMCIAP_01923	4.68e-99	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
IHHMCIAP_01924	2.01e-214	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IHHMCIAP_01925	1.5e-174	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
IHHMCIAP_01926	2.21e-228	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
IHHMCIAP_01927	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
IHHMCIAP_01928	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
IHHMCIAP_01929	1.49e-254	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
IHHMCIAP_01930	1.69e-256	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
IHHMCIAP_01931	1.83e-258	-	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IHHMCIAP_01932	2.37e-50	pbg4	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
IHHMCIAP_01933	5e-57	celA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	beta-glucosidase activity
IHHMCIAP_01934	0.0	copB	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
IHHMCIAP_01935	2.55e-123	mdt(A)	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Major facilitator Superfamily