ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
HFLOMJMM_00001 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HFLOMJMM_00002 8.49e-265 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HFLOMJMM_00003 5.41e-47 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain protein YaaA
HFLOMJMM_00004 2.07e-262 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HFLOMJMM_00005 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HFLOMJMM_00006 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HFLOMJMM_00007 4.55e-64 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
HFLOMJMM_00008 1.03e-114 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HFLOMJMM_00009 9.36e-48 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HFLOMJMM_00010 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
HFLOMJMM_00011 1.25e-97 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
HFLOMJMM_00012 3.65e-308 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
HFLOMJMM_00013 3.37e-272 yttB - - EGP - - - Major Facilitator
HFLOMJMM_00014 1.56e-80 - - - - - - - -
HFLOMJMM_00015 1.36e-212 - - - S - - - Polyphosphate nucleotide phosphotransferase, PPK2 family
HFLOMJMM_00016 5.2e-132 - - - K - - - DNA-binding helix-turn-helix protein
HFLOMJMM_00018 6.55e-97 - - - K ko:K18909 - ko00000,ko00002,ko01504,ko03000 helix_turn_helix multiple antibiotic resistance protein
HFLOMJMM_00019 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
HFLOMJMM_00021 1.29e-168 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
HFLOMJMM_00022 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HFLOMJMM_00023 0.0 yycH - - S - - - YycH protein
HFLOMJMM_00024 6.38e-196 yycI - - S - - - YycH protein
HFLOMJMM_00025 3.06e-197 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
HFLOMJMM_00026 6.24e-287 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
HFLOMJMM_00027 5.79e-117 pgpA - - I - - - Phosphatidylglycerophosphatase A
HFLOMJMM_00028 1.02e-232 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
HFLOMJMM_00029 2.63e-115 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HFLOMJMM_00031 1.56e-125 - - - S - - - reductase
HFLOMJMM_00032 1.08e-288 dhaT 1.1.1.202 - C ko:K00086 ko00561,ko00640,map00561,map00640 ko00000,ko00001,ko01000 Dehydrogenase
HFLOMJMM_00033 8.4e-200 - - - U ko:K05340 - ko00000,ko02000 sugar transport
HFLOMJMM_00034 3.72e-193 - - - E - - - Glyoxalase-like domain
HFLOMJMM_00035 2.13e-189 - 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HFLOMJMM_00036 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
HFLOMJMM_00037 1.06e-202 hlyD3 - - M ko:K02005 - ko00000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HFLOMJMM_00038 1.69e-167 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
HFLOMJMM_00039 3.16e-278 - - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
HFLOMJMM_00041 7.63e-64 - - - - - - - -
HFLOMJMM_00042 0.0 - - - S - - - Putative peptidoglycan binding domain
HFLOMJMM_00045 1.37e-35 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
HFLOMJMM_00046 6.86e-98 - - - O - - - OsmC-like protein
HFLOMJMM_00047 5.24e-232 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HFLOMJMM_00048 2.83e-282 - - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HFLOMJMM_00049 8.68e-44 - - - - - - - -
HFLOMJMM_00050 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 associated with various cellular activities
HFLOMJMM_00052 1.22e-139 - - - K - - - PFAM GCN5-related N-acetyltransferase
HFLOMJMM_00053 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HFLOMJMM_00054 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HFLOMJMM_00055 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
HFLOMJMM_00056 9.34e-225 malR1 - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
HFLOMJMM_00057 4.84e-277 atoB 1.1.1.88, 2.3.1.9 - I ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
HFLOMJMM_00058 0.0 malT - - G ko:K16211 - ko00000,ko02000 Major Facilitator
HFLOMJMM_00059 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
HFLOMJMM_00060 4.32e-155 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
HFLOMJMM_00061 8.58e-94 - - - - - - - -
HFLOMJMM_00062 2.92e-111 - - - T - - - Region found in RelA / SpoT proteins
HFLOMJMM_00063 1.1e-153 dltr - - K - - - response regulator
HFLOMJMM_00064 5.59e-290 sptS - - T - - - Histidine kinase
HFLOMJMM_00065 7.76e-279 - - - P - - - Voltage gated chloride channel
HFLOMJMM_00066 0.0 gshAB 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
HFLOMJMM_00067 4.71e-112 - - - L ko:K07491 - ko00000 PFAM transposase IS200-family protein
HFLOMJMM_00068 1.29e-176 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
HFLOMJMM_00069 1.54e-216 - - - C - - - Aldo keto reductase
HFLOMJMM_00070 0.0 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Membrane domain of glycerophosphoryl diester phosphodiesterase
HFLOMJMM_00071 6.51e-114 - - - S - - - ECF-type riboflavin transporter, S component
HFLOMJMM_00072 0.0 nox 1.6.3.4 - C ko:K17869 - ko00000,ko01000 NADH oxidase
HFLOMJMM_00073 2.95e-239 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HFLOMJMM_00074 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HFLOMJMM_00075 2.31e-131 - - - - - - - -
HFLOMJMM_00076 1.14e-123 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HFLOMJMM_00078 3.62e-308 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HFLOMJMM_00079 4.72e-107 - - - L ko:K07491 - ko00000 Transposase IS200 like
HFLOMJMM_00080 8.71e-178 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
HFLOMJMM_00081 5.46e-315 - - - E - - - amino acid
HFLOMJMM_00082 1.64e-18 - - - K - - - Transcriptional regulator, TetR family
HFLOMJMM_00083 4.39e-94 - - - K - - - Transcriptional regulator, TetR family
HFLOMJMM_00084 8.53e-95 - - - - - - - -
HFLOMJMM_00085 0.0 tagE 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
HFLOMJMM_00086 0.0 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Poly(Glycerol-phosphate) alpha-glucosyltransferase
HFLOMJMM_00087 0.0 - - - M - - - domain protein
HFLOMJMM_00088 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
HFLOMJMM_00089 0.0 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
HFLOMJMM_00090 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
HFLOMJMM_00091 3.22e-269 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
HFLOMJMM_00092 0.0 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
HFLOMJMM_00093 2.07e-236 cytR - - K ko:K02529,ko:K03604 - ko00000,ko03000 Transcriptional regulator, LacI family
HFLOMJMM_00094 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HFLOMJMM_00096 6e-132 - 1.5.1.36 - S ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 reductase
HFLOMJMM_00097 3e-274 - 1.5.1.36 - S ko:K19784,ko:K22393,ko:K22394 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 reductase
HFLOMJMM_00098 2.4e-230 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HFLOMJMM_00099 0.0 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HFLOMJMM_00100 8.5e-266 - - - M - - - Rib/alpha-like repeat
HFLOMJMM_00101 9.62e-94 - - - L - - - PFAM Integrase catalytic region
HFLOMJMM_00102 0.0 - - - M - - - Rib/alpha-like repeat
HFLOMJMM_00103 0.0 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HFLOMJMM_00104 0.0 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HFLOMJMM_00105 3.99e-178 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HFLOMJMM_00106 2.25e-288 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
HFLOMJMM_00107 1.69e-278 nupG - - F ko:K03317,ko:K11535,ko:K16323 - ko00000,ko02000 Nucleoside transporter
HFLOMJMM_00108 2.47e-220 rihA 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
HFLOMJMM_00109 1.08e-210 - 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 3-hydroxyacyl-CoA dehydrogenase
HFLOMJMM_00110 9.71e-167 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
HFLOMJMM_00111 3.57e-198 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
HFLOMJMM_00112 8.34e-180 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
HFLOMJMM_00113 1.68e-198 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
HFLOMJMM_00114 8.24e-43 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
HFLOMJMM_00115 6.1e-255 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HFLOMJMM_00116 6.3e-175 - - - S - - - Protein of unknown function (DUF1129)
HFLOMJMM_00117 5.64e-153 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HFLOMJMM_00118 6.87e-300 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
HFLOMJMM_00119 5.15e-306 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 pyrimidine-nucleoside phosphorylase
HFLOMJMM_00120 3.27e-167 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
HFLOMJMM_00121 5.59e-221 deoR - - K ko:K05346 - ko00000,ko03000 sugar-binding domain protein
HFLOMJMM_00122 1.47e-265 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HFLOMJMM_00123 9.76e-161 vanR - - K - - - response regulator
HFLOMJMM_00124 1.36e-266 hpk31 - - T - - - Histidine kinase
HFLOMJMM_00125 6.03e-196 - - - E - - - AzlC protein
HFLOMJMM_00126 4.05e-70 - - - S - - - branched-chain amino acid
HFLOMJMM_00127 1.3e-156 - - - K ko:K09681 - ko00000,ko03000 DNA-binding transcription factor activity
HFLOMJMM_00128 1.56e-20 - - - K - - - LysR substrate binding domain
HFLOMJMM_00129 1.81e-221 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
HFLOMJMM_00130 3.19e-315 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HFLOMJMM_00131 2.77e-220 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HFLOMJMM_00132 1.96e-167 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HFLOMJMM_00133 6.66e-151 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HFLOMJMM_00134 1.4e-152 - - - S - - - Haloacid dehalogenase-like hydrolase
HFLOMJMM_00135 1.4e-302 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
HFLOMJMM_00136 5.53e-223 ydbI - - K - - - AI-2E family transporter
HFLOMJMM_00137 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
HFLOMJMM_00138 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
HFLOMJMM_00139 4.32e-173 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Belongs to the alpha-acetolactate decarboxylase family
HFLOMJMM_00140 8.95e-110 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HFLOMJMM_00141 1.75e-275 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HFLOMJMM_00142 0.0 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HFLOMJMM_00143 2.7e-172 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
HFLOMJMM_00144 7.76e-51 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HFLOMJMM_00145 1.19e-164 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HFLOMJMM_00146 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HFLOMJMM_00147 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HFLOMJMM_00148 8.29e-252 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
HFLOMJMM_00149 4.09e-136 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HFLOMJMM_00150 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
HFLOMJMM_00151 4.44e-314 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
HFLOMJMM_00152 5.27e-169 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HFLOMJMM_00153 4.86e-237 - - - - - - - -
HFLOMJMM_00154 2.97e-306 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HFLOMJMM_00157 1.5e-85 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
HFLOMJMM_00158 0.0 - - - L ko:K07484 - ko00000 Transposase IS66 family
HFLOMJMM_00160 3.87e-112 - - - - - - - -
HFLOMJMM_00161 6.73e-244 - - - L - - - PFAM Integrase catalytic region
HFLOMJMM_00162 1.69e-170 - - - F - - - NUDIX domain
HFLOMJMM_00163 0.0 nadC2 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HFLOMJMM_00164 3.53e-135 pncA - - Q - - - Isochorismatase family
HFLOMJMM_00165 2.34e-266 - - - O - - - ADP-ribosylglycohydrolase
HFLOMJMM_00166 0.0 - - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
HFLOMJMM_00167 2.09e-213 - - - G - - - Belongs to the carbohydrate kinase PfkB family
HFLOMJMM_00168 1.07e-52 hxlR - - K - - - regulation of RNA biosynthetic process
HFLOMJMM_00169 1.05e-309 - - - EGP - - - MFS transporter, metabolite H symporter (MHS) family protein
HFLOMJMM_00170 1.89e-171 - - - IQ - - - dehydrogenase reductase
HFLOMJMM_00171 2.33e-51 - - - - - - - -
HFLOMJMM_00172 1.39e-149 - - - S ko:K07118 - ko00000 NAD(P)H-binding
HFLOMJMM_00173 2.3e-52 - - - S - - - Cytochrome b5-like Heme/Steroid binding domain
HFLOMJMM_00174 0.0 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
HFLOMJMM_00175 1.86e-136 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HFLOMJMM_00176 1.2e-63 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HFLOMJMM_00178 3.04e-133 - - - S ko:K07002 - ko00000 Serine hydrolase
HFLOMJMM_00179 6.25e-83 psiE - - S ko:K13256 - ko00000 Phosphate-starvation-inducible E
HFLOMJMM_00180 6.12e-182 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HFLOMJMM_00182 3.04e-233 ydhF - - S - - - Aldo keto reductase
HFLOMJMM_00183 1.31e-109 - 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 PAP2 superfamily
HFLOMJMM_00184 0.0 - - - L - - - Helicase C-terminal domain protein
HFLOMJMM_00186 0.0 - 1.8.1.7 - C ko:K00383,ko:K21739 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Pyridine nucleotide-disulfide oxidoreductase
HFLOMJMM_00187 2.84e-73 - - - S - - - Sugar efflux transporter for intercellular exchange
HFLOMJMM_00188 2.31e-166 - - - - - - - -
HFLOMJMM_00189 3e-167 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
HFLOMJMM_00190 0.0 cadA - - P - - - P-type ATPase
HFLOMJMM_00191 5.8e-291 - 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Metalloenzyme superfamily
HFLOMJMM_00192 4.44e-11 - - - - - - - -
HFLOMJMM_00193 5.1e-204 - - - GM - - - NAD(P)H-binding
HFLOMJMM_00194 1.07e-68 ywnA - - K - - - Transcriptional regulator
HFLOMJMM_00195 1.85e-209 proWY - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, QAT family
HFLOMJMM_00196 2.86e-140 proWZ - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HFLOMJMM_00197 6.38e-184 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HFLOMJMM_00198 6.84e-139 - - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, permease protein
HFLOMJMM_00199 7.7e-104 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
HFLOMJMM_00200 0.0 eriC - - P ko:K03281 - ko00000 chloride
HFLOMJMM_00201 6.12e-279 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
HFLOMJMM_00202 5.25e-140 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HFLOMJMM_00203 1.04e-245 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HFLOMJMM_00204 5.28e-201 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
HFLOMJMM_00205 1.26e-217 hdhL 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
HFLOMJMM_00206 2.41e-280 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 transporter
HFLOMJMM_00207 3.07e-58 - 1.3.5.4 - S ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FMN binding
HFLOMJMM_00208 4.89e-153 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HFLOMJMM_00209 0.0 ctrA - - E ko:K03294 - ko00000 amino acid
HFLOMJMM_00210 0.0 gabT 2.6.1.19, 5.1.1.21 - E ko:K00823,ko:K20708 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HFLOMJMM_00212 1.1e-260 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HFLOMJMM_00213 0.0 - - - L - - - DNA helicase
HFLOMJMM_00214 2.02e-106 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Belongs to the NDK family
HFLOMJMM_00215 5.96e-241 - 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 Belongs to the N(4) N(6)-methyltransferase family
HFLOMJMM_00216 1.36e-243 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
HFLOMJMM_00217 2.53e-214 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
HFLOMJMM_00218 1.98e-297 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
HFLOMJMM_00219 1.33e-228 - - - - - - - -
HFLOMJMM_00220 1.51e-170 cobB - - K ko:K12410 - ko00000,ko01000 SIR2 family
HFLOMJMM_00222 1.16e-208 yunF - - F - - - Protein of unknown function DUF72
HFLOMJMM_00223 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HFLOMJMM_00224 5.77e-201 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
HFLOMJMM_00225 1.04e-128 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HFLOMJMM_00226 3.73e-208 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HFLOMJMM_00227 2.74e-50 veg - - S - - - Biofilm formation stimulator VEG
HFLOMJMM_00228 1.71e-206 ispE 2.7.1.148 - F ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HFLOMJMM_00229 5.16e-218 psaA - - P ko:K02077,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
HFLOMJMM_00230 4.85e-158 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HFLOMJMM_00231 4.31e-166 - - - U ko:K02075 - ko00000,ko00002,ko02000 ABC 3 transport family
HFLOMJMM_00232 2.09e-190 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
HFLOMJMM_00233 2.74e-316 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HFLOMJMM_00234 3.53e-229 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HFLOMJMM_00235 2.4e-102 - - - - - - - -
HFLOMJMM_00236 2.06e-193 yidA - - S - - - hydrolase
HFLOMJMM_00237 0.0 ywfO - - S ko:K06885 - ko00000 HD domain protein
HFLOMJMM_00238 2.16e-200 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 biotin lipoate A B protein ligase
HFLOMJMM_00239 1.2e-80 - - - L ko:K07491 - ko00000 PFAM transposase IS200-family protein
HFLOMJMM_00240 1.54e-293 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HFLOMJMM_00241 1.95e-90 ywiB - - S - - - Domain of unknown function (DUF1934)
HFLOMJMM_00242 3.49e-82 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HFLOMJMM_00243 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HFLOMJMM_00244 0.0 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HFLOMJMM_00245 6.72e-303 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HFLOMJMM_00246 9.43e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
HFLOMJMM_00247 2.02e-306 pts13C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HFLOMJMM_00248 8.23e-216 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HFLOMJMM_00249 4.29e-162 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
HFLOMJMM_00250 3.01e-179 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HFLOMJMM_00251 1.59e-209 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
HFLOMJMM_00252 1.84e-155 - - - G - - - Belongs to the phosphoglycerate mutase family
HFLOMJMM_00253 5.7e-114 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HFLOMJMM_00254 4.93e-123 lemA - - S ko:K03744 - ko00000 LemA family
HFLOMJMM_00255 1.84e-204 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
HFLOMJMM_00256 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HFLOMJMM_00257 0.0 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HFLOMJMM_00258 4.68e-197 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HFLOMJMM_00259 6.14e-215 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
HFLOMJMM_00260 4.71e-112 - - - L ko:K07491 - ko00000 PFAM transposase IS200-family protein
HFLOMJMM_00261 0.0 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HFLOMJMM_00262 0.0 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HFLOMJMM_00263 4.98e-48 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HFLOMJMM_00264 3.3e-302 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
HFLOMJMM_00265 0.0 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HFLOMJMM_00266 2.63e-08 dltX - - S - - - D-Ala-teichoic acid biosynthesis protein
HFLOMJMM_00267 2.29e-81 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HFLOMJMM_00268 2.28e-271 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HFLOMJMM_00269 1.3e-82 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
HFLOMJMM_00270 0.0 - - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
HFLOMJMM_00271 9.6e-310 codA 3.5.4.1 - F ko:K01485 ko00240,ko00330,ko01100,map00240,map00330,map01100 ko00000,ko00001,ko01000 cytosine deaminase
HFLOMJMM_00272 2.06e-188 mhpD - - Q ko:K02509 ko00350,ko01120,map00350,map01120 ko00000,ko00001,ko01000 hydratase
HFLOMJMM_00273 8.08e-147 - - - S - - - (CBS) domain
HFLOMJMM_00274 1.38e-132 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HFLOMJMM_00275 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HFLOMJMM_00276 1.01e-52 yabO - - J - - - S4 domain protein
HFLOMJMM_00277 4.31e-76 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
HFLOMJMM_00278 5.75e-103 yabR - - J ko:K07571 - ko00000 RNA binding
HFLOMJMM_00279 0.0 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HFLOMJMM_00280 1.05e-124 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
HFLOMJMM_00281 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HFLOMJMM_00282 2.77e-219 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HFLOMJMM_00283 2.64e-242 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HFLOMJMM_00284 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
HFLOMJMM_00285 6.85e-115 - - - - - - - -
HFLOMJMM_00289 2.21e-87 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
HFLOMJMM_00290 0.0 - - - L ko:K07484 - ko00000 Transposase IS66 family
HFLOMJMM_00293 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
HFLOMJMM_00294 2.01e-206 - - - S - - - Calcineurin-like phosphoesterase
HFLOMJMM_00297 5.92e-150 - - - - - - - -
HFLOMJMM_00298 0.0 - - - EGP - - - Major Facilitator
HFLOMJMM_00299 0.0 - - - P ko:K07085 - ko00000 Predicted Permease Membrane Region
HFLOMJMM_00300 5.9e-170 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
HFLOMJMM_00301 3.54e-165 yvoA_2 - - K ko:K03710 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
HFLOMJMM_00302 0.0 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HFLOMJMM_00303 1.84e-197 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HFLOMJMM_00304 0.0 tex - - K ko:K06959 - ko00000 Tex-like protein N-terminal domain protein
HFLOMJMM_00305 2e-112 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
HFLOMJMM_00307 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
HFLOMJMM_00308 9.89e-240 lacM 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase
HFLOMJMM_00309 0.0 - - - S - - - Bacterial membrane protein, YfhO
HFLOMJMM_00310 3.04e-172 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HFLOMJMM_00311 7.63e-217 - - - I - - - alpha/beta hydrolase fold
HFLOMJMM_00312 4.46e-276 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
HFLOMJMM_00313 3.36e-154 tcyB - - E ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HFLOMJMM_00314 1.75e-173 - - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HFLOMJMM_00315 3.01e-181 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
HFLOMJMM_00316 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
HFLOMJMM_00317 2.5e-162 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HFLOMJMM_00318 1.65e-66 yjdJ - - S ko:K06975 - ko00000 GCN5-related N-acetyl-transferase
HFLOMJMM_00319 1.02e-130 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
HFLOMJMM_00320 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HFLOMJMM_00321 2.54e-266 yacL - - S - - - domain protein
HFLOMJMM_00322 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
HFLOMJMM_00323 2.16e-94 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HFLOMJMM_00324 1.82e-175 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HFLOMJMM_00325 9.18e-31 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
HFLOMJMM_00326 7.11e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HFLOMJMM_00327 1.1e-126 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
HFLOMJMM_00328 1.39e-92 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HFLOMJMM_00329 8.31e-158 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HFLOMJMM_00330 9.63e-291 aadAT - - EK ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko01000 Aminotransferase, class I
HFLOMJMM_00332 0.0 - - - M - - - Glycosyl transferase family group 2
HFLOMJMM_00333 4.1e-273 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HFLOMJMM_00334 3.6e-107 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HFLOMJMM_00335 2.46e-72 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HFLOMJMM_00336 8.34e-65 - - - - - - - -
HFLOMJMM_00338 2.94e-65 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HFLOMJMM_00339 1.38e-75 XK27_06915 - - K ko:K10947 - ko00000,ko03000 transcriptional regulator PadR family
HFLOMJMM_00340 5.64e-129 - - - S - - - Protein of unknown function (DUF1700)
HFLOMJMM_00341 3.67e-176 - - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
HFLOMJMM_00342 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
HFLOMJMM_00343 1.14e-255 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HFLOMJMM_00344 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HFLOMJMM_00345 9.33e-48 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
HFLOMJMM_00346 6.21e-119 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HFLOMJMM_00347 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HFLOMJMM_00348 5.87e-62 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HFLOMJMM_00349 4.92e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HFLOMJMM_00350 4.67e-52 - - - S - - - Protein of unknown function (DUF2508)
HFLOMJMM_00351 1.11e-149 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HFLOMJMM_00352 2.83e-69 yaaQ - - S - - - Cyclic-di-AMP receptor
HFLOMJMM_00353 2.72e-237 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
HFLOMJMM_00354 6.41e-77 yabA - - L - - - Involved in initiation control of chromosome replication
HFLOMJMM_00355 9.87e-204 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HFLOMJMM_00356 2.92e-183 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
HFLOMJMM_00357 0.0 ppx3 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
HFLOMJMM_00358 0.0 ppk 2.7.4.1 - P ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HFLOMJMM_00359 1.43e-225 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
HFLOMJMM_00360 1.48e-247 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
HFLOMJMM_00361 1.52e-270 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
HFLOMJMM_00362 1.93e-40 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
HFLOMJMM_00363 5.86e-168 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
HFLOMJMM_00364 3.02e-135 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 Ribosomal-protein-alanine acetyltransferase
HFLOMJMM_00365 1.74e-252 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HFLOMJMM_00366 1.87e-172 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HFLOMJMM_00367 1.62e-293 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HFLOMJMM_00368 2.29e-180 proB 2.7.2.11 - F ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HFLOMJMM_00369 3.05e-189 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Carbon-nitrogen hydrolase
HFLOMJMM_00370 1.37e-292 mtnE - - E ko:K08969 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HFLOMJMM_00371 1.92e-238 ykpB 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HFLOMJMM_00372 0.0 - - - L - - - Transposase
HFLOMJMM_00373 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
HFLOMJMM_00374 4.67e-147 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HFLOMJMM_00376 1.83e-59 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HFLOMJMM_00377 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HFLOMJMM_00378 3.5e-112 - - - S ko:K19055 - ko00000,ko01000,ko03016 Aminoacyl-tRNA editing domain
HFLOMJMM_00379 0.0 - - - E - - - amino acid
HFLOMJMM_00380 0.0 ydaO - - E - - - amino acid
HFLOMJMM_00381 2.63e-53 - - - - - - - -
HFLOMJMM_00382 3.07e-89 - - - K - - - Transcriptional regulator
HFLOMJMM_00383 0.0 - - - EGP - - - Major Facilitator
HFLOMJMM_00384 1.4e-146 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
HFLOMJMM_00385 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
HFLOMJMM_00386 1.4e-163 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
HFLOMJMM_00387 3.01e-125 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HFLOMJMM_00388 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HFLOMJMM_00389 4.72e-240 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HFLOMJMM_00390 3.65e-67 - - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain protein
HFLOMJMM_00391 1.88e-68 yvlD - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
HFLOMJMM_00392 1.38e-226 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HFLOMJMM_00393 4.38e-205 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HFLOMJMM_00394 5.93e-237 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
HFLOMJMM_00395 1.08e-215 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
HFLOMJMM_00396 4.49e-178 lutC - - S ko:K00782 - ko00000 LUD domain
HFLOMJMM_00397 0.0 lutB - - C ko:K18929 - ko00000 4Fe-4S dicluster domain
HFLOMJMM_00398 2.37e-216 lutA - - C ko:K18928 - ko00000 Cysteine-rich domain
HFLOMJMM_00399 2.04e-223 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HFLOMJMM_00400 1.45e-281 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
HFLOMJMM_00401 5.33e-211 - - - ET ko:K02030 - ko00000,ko00002,ko02000 PFAM extracellular solute-binding protein, family 3
HFLOMJMM_00402 5.98e-116 ykhA 3.1.2.20 - I ko:K01073 - ko00000,ko01000 Thioesterase superfamily
HFLOMJMM_00403 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HFLOMJMM_00404 3.57e-150 yfbR - - S ko:K07023 - ko00000 HD containing hydrolase-like enzyme
HFLOMJMM_00405 2.12e-19 - - - - - - - -
HFLOMJMM_00406 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HFLOMJMM_00407 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HFLOMJMM_00408 9.18e-317 steT - - E ko:K03294 - ko00000 amino acid
HFLOMJMM_00409 3.42e-209 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
HFLOMJMM_00410 6.97e-240 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
HFLOMJMM_00411 6.77e-219 whiA - - K ko:K09762 - ko00000 May be required for sporulation
HFLOMJMM_00413 1.83e-21 - - - - - - - -
HFLOMJMM_00414 4.72e-134 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HFLOMJMM_00415 0.0 - - - L - - - Transposase
HFLOMJMM_00416 2.26e-20 - - - L - - - Transposase
HFLOMJMM_00418 1.31e-243 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HFLOMJMM_00419 3.1e-289 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
HFLOMJMM_00420 2.51e-182 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HFLOMJMM_00421 0.0 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HFLOMJMM_00422 0.0 - - - L - - - Transposase
HFLOMJMM_00423 0.0 yifK - - E ko:K03293 - ko00000 Amino acid permease
HFLOMJMM_00424 0.0 eriC - - P ko:K03281 - ko00000 chloride
HFLOMJMM_00425 1.43e-47 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
HFLOMJMM_00426 6.17e-192 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Serine aminopeptidase, S33
HFLOMJMM_00427 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HFLOMJMM_00428 7.73e-109 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HFLOMJMM_00429 9.61e-137 - - - - - - - -
HFLOMJMM_00430 1.84e-174 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HFLOMJMM_00431 1.38e-228 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
HFLOMJMM_00432 1.2e-105 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
HFLOMJMM_00433 2.63e-115 - - - K - - - Acetyltransferase (GNAT) domain
HFLOMJMM_00434 6.13e-100 XK27_04775 - - S ko:K09155 - ko00000 PAS domain
HFLOMJMM_00435 6.9e-134 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
HFLOMJMM_00436 2.36e-216 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
HFLOMJMM_00437 2.26e-214 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HFLOMJMM_00438 2.47e-88 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HFLOMJMM_00439 0.0 fucP - - G ko:K02429 - ko00000,ko02000 Major Facilitator Superfamily
HFLOMJMM_00440 6.61e-195 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HFLOMJMM_00441 1.99e-165 ybbR - - S - - - YbbR-like protein
HFLOMJMM_00442 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HFLOMJMM_00443 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HFLOMJMM_00444 5.17e-70 - - - - - - - -
HFLOMJMM_00445 0.0 oatA - - I - - - Acyltransferase
HFLOMJMM_00446 7.53e-104 - - - K - - - Transcriptional regulator
HFLOMJMM_00447 4.88e-194 - - - S - - - Cof-like hydrolase
HFLOMJMM_00448 2.2e-110 lytE - - M - - - Lysin motif
HFLOMJMM_00450 2.06e-176 yclJ - - K ko:K02483 - ko00000,ko02022 response regulator
HFLOMJMM_00451 0.0 yclK - - T - - - Histidine kinase
HFLOMJMM_00452 7.78e-200 - - - U ko:K05340 - ko00000,ko02000 sugar transport
HFLOMJMM_00453 2.09e-154 maa3 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
HFLOMJMM_00454 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
HFLOMJMM_00455 2.69e-36 - - - - - - - -
HFLOMJMM_00457 6.11e-44 xylB 2.7.1.17, 2.7.1.53 - G ko:K00854,ko:K00880 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the FGGY kinase family
HFLOMJMM_00458 3.87e-111 - - - L ko:K07491 - ko00000 PFAM transposase IS200-family protein
HFLOMJMM_00459 2.24e-200 - - - KT ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 YcbB domain
HFLOMJMM_00460 9.21e-244 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HFLOMJMM_00461 1.37e-221 arcC 2.7.2.2 - E ko:K00926 ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200 ko00000,ko00001,ko01000 Belongs to the carbamate kinase family
HFLOMJMM_00462 1.92e-209 - - - EG - - - EamA-like transporter family
HFLOMJMM_00463 1.04e-135 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
HFLOMJMM_00464 1.53e-71 - - - S - - - Cupredoxin-like domain
HFLOMJMM_00465 2.2e-65 - - - S - - - Cupredoxin-like domain
HFLOMJMM_00466 0.0 copA 3.6.3.3, 3.6.3.5, 3.6.3.54 - P ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
HFLOMJMM_00467 2.91e-118 - - - - - - - -
HFLOMJMM_00469 1.28e-75 - - - - - - - -
HFLOMJMM_00470 6.08e-305 nhaP3 - - P ko:K03316 - ko00000 Sodium proton antiporter
HFLOMJMM_00474 1.52e-303 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HFLOMJMM_00475 3.92e-87 - - - - - - - -
HFLOMJMM_00477 1.6e-94 - - - - - - - -
HFLOMJMM_00479 1.38e-05 - - - - - - - -
HFLOMJMM_00482 2.49e-180 - - - L ko:K07497 - ko00000 hmm pf00665
HFLOMJMM_00483 1.21e-137 - - - L - - - Helix-turn-helix domain
HFLOMJMM_00484 2.51e-83 - - - - - - - -
HFLOMJMM_00485 3e-251 ampC - - V - - - Beta-lactamase
HFLOMJMM_00486 1.25e-304 arcA 3.5.3.6 - E ko:K01478 ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130 ko00000,ko00001,ko01000 Arginine
HFLOMJMM_00487 3.05e-104 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
HFLOMJMM_00488 0.0 arcD - - E ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
HFLOMJMM_00489 1.07e-301 potE - - U ko:K03756,ko:K03758 - ko00000,ko02000 Amino acid permease
HFLOMJMM_00490 1.19e-173 - - - S ko:K07009 - ko00000 CobB/CobQ-like glutamine amidotransferase domain
HFLOMJMM_00491 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Mur ligase, middle domain
HFLOMJMM_00492 6.8e-140 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
HFLOMJMM_00493 1.73e-248 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HFLOMJMM_00494 7.63e-217 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HFLOMJMM_00495 6.56e-252 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HFLOMJMM_00496 9.39e-296 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HFLOMJMM_00497 6.68e-150 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HFLOMJMM_00498 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HFLOMJMM_00499 1.27e-250 yibE - - S - - - overlaps another CDS with the same product name
HFLOMJMM_00500 4.22e-169 yibF - - S - - - overlaps another CDS with the same product name
HFLOMJMM_00501 9.76e-295 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
HFLOMJMM_00502 4.63e-162 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
HFLOMJMM_00503 1.26e-29 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HFLOMJMM_00504 1.07e-95 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HFLOMJMM_00505 6.84e-121 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HFLOMJMM_00506 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HFLOMJMM_00507 1.3e-212 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HFLOMJMM_00508 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HFLOMJMM_00509 8.95e-90 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
HFLOMJMM_00510 1.76e-45 ywzB - - S - - - Protein of unknown function (DUF1146)
HFLOMJMM_00511 7.7e-311 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HFLOMJMM_00512 2.57e-227 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
HFLOMJMM_00513 3.77e-56 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
HFLOMJMM_00514 7.96e-45 - - - S - - - Protein of unknown function (DUF2969)
HFLOMJMM_00515 4.7e-282 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
HFLOMJMM_00516 2.98e-64 gcsH2 - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 glycine cleavage
HFLOMJMM_00517 0.0 - - - S - - - Uncharacterised protein family (UPF0236)
HFLOMJMM_00518 5.42e-276 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
HFLOMJMM_00519 6.61e-194 - - - K - - - Helix-turn-helix XRE-family like proteins
HFLOMJMM_00520 0.0 araP - - U - - - Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HFLOMJMM_00521 0.0 araB 2.7.1.16 - G ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 carbohydrate kinase FGGY
HFLOMJMM_00522 2.32e-179 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
HFLOMJMM_00523 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
HFLOMJMM_00524 2.28e-137 maa 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
HFLOMJMM_00525 3.74e-204 yvgN - - S - - - Aldo keto reductase
HFLOMJMM_00526 1.3e-265 araR - - K ko:K02103 - ko00000,ko03000 Transcriptional regulator
HFLOMJMM_00527 1.95e-109 uspA - - T - - - universal stress protein
HFLOMJMM_00528 3.61e-61 - - - - - - - -
HFLOMJMM_00529 4.83e-312 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
HFLOMJMM_00530 3.65e-114 XK27_05190 - - S - - - Protein of unknown function (DUF1694)
HFLOMJMM_00531 1.14e-27 - - - - - - - -
HFLOMJMM_00532 4.92e-99 - 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase
HFLOMJMM_00533 4.16e-180 - - - S - - - Membrane
HFLOMJMM_00534 1.24e-182 - - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
HFLOMJMM_00535 0.0 spxB 1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8 - EH ko:K00156,ko:K00158,ko:K01577,ko:K01652 ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
HFLOMJMM_00536 6.74e-209 frc 2.8.3.16 - C ko:K07749 - ko00000,ko01000 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HFLOMJMM_00537 4.71e-112 - - - L ko:K07491 - ko00000 PFAM transposase IS200-family protein
HFLOMJMM_00538 2.45e-110 frc 2.8.3.16 - C ko:K07749 - ko00000,ko01000 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HFLOMJMM_00539 0.0 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HFLOMJMM_00540 1.14e-300 pbuG - - S ko:K06901 - ko00000,ko02000 permease
HFLOMJMM_00541 5.96e-139 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HFLOMJMM_00542 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HFLOMJMM_00543 2.59e-276 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
HFLOMJMM_00544 4.1e-292 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HFLOMJMM_00545 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HFLOMJMM_00546 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
HFLOMJMM_00547 2.07e-237 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase subunit II
HFLOMJMM_00548 0.0 cydC - - CO ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HFLOMJMM_00549 0.0 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HFLOMJMM_00550 1.09e-295 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
HFLOMJMM_00551 9.51e-317 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
HFLOMJMM_00552 3.6e-158 radC - - L ko:K03630 - ko00000 DNA repair protein
HFLOMJMM_00553 8.33e-230 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
HFLOMJMM_00554 7.72e-195 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
HFLOMJMM_00555 1.69e-120 mreD - - M ko:K03571 - ko00000,ko03036 rod shape-determining protein MreD
HFLOMJMM_00556 3.13e-141 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
HFLOMJMM_00557 1.45e-151 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HFLOMJMM_00558 2.84e-205 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
HFLOMJMM_00559 3.68e-295 ymfF - - S - - - Peptidase M16 inactive domain protein
HFLOMJMM_00560 0.0 ymfH - - S - - - Peptidase M16
HFLOMJMM_00561 7.21e-198 ymfM - - S ko:K15539 - ko00000 Helix-turn-helix domain
HFLOMJMM_00562 1.16e-133 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HFLOMJMM_00563 6.36e-296 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
HFLOMJMM_00564 7.67e-252 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HFLOMJMM_00565 2.29e-276 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
HFLOMJMM_00566 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HFLOMJMM_00567 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HFLOMJMM_00568 4.52e-133 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HFLOMJMM_00569 9.97e-245 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HFLOMJMM_00570 1.11e-260 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HFLOMJMM_00571 1.86e-62 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
HFLOMJMM_00572 2.15e-234 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
HFLOMJMM_00573 0.0 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HFLOMJMM_00574 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HFLOMJMM_00575 8.03e-58 yrzL - - S - - - Belongs to the UPF0297 family
HFLOMJMM_00576 3.62e-100 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HFLOMJMM_00577 3.75e-63 yrzB - - S - - - Belongs to the UPF0473 family
HFLOMJMM_00578 7.15e-122 cvpA - - S - - - Colicin V production protein
HFLOMJMM_00579 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HFLOMJMM_00580 2.86e-72 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
HFLOMJMM_00581 3.01e-126 yslB - - S - - - Protein of unknown function (DUF2507)
HFLOMJMM_00582 3.41e-189 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
HFLOMJMM_00583 1.53e-138 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HFLOMJMM_00584 1.16e-124 - - - S ko:K07095 - ko00000 Phosphoesterase
HFLOMJMM_00585 1.79e-100 ykuL - - S - - - (CBS) domain
HFLOMJMM_00586 1.4e-198 - - - S - - - haloacid dehalogenase-like hydrolase
HFLOMJMM_00587 1.6e-190 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
HFLOMJMM_00588 1.54e-71 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HFLOMJMM_00589 2.93e-58 - - - - - - - -
HFLOMJMM_00590 6.25e-272 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
HFLOMJMM_00591 1.7e-235 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
HFLOMJMM_00592 1.03e-181 - - - - - - - -
HFLOMJMM_00593 1.22e-168 yebC - - K - - - Transcriptional regulatory protein
HFLOMJMM_00594 8.77e-237 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
HFLOMJMM_00595 2.95e-240 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
HFLOMJMM_00596 6.31e-62 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 competence protein ComGC
HFLOMJMM_00597 3.65e-103 - - - NU ko:K02246 - ko00000,ko00002,ko02044 general secretion pathway protein
HFLOMJMM_00598 3.65e-60 - - - - - - - -
HFLOMJMM_00599 1.01e-95 - - - - ko:K02248 - ko00000,ko00002,ko02044 -
HFLOMJMM_00601 3.58e-186 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
HFLOMJMM_00602 1.36e-286 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HFLOMJMM_00603 6.01e-153 - - - S - - - Calcineurin-like phosphoesterase
HFLOMJMM_00604 3.03e-129 yutD - - S - - - Protein of unknown function (DUF1027)
HFLOMJMM_00605 1.44e-180 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HFLOMJMM_00606 7.15e-148 - - - S - - - Protein of unknown function (DUF1461)
HFLOMJMM_00607 1.29e-149 dedA - - S ko:K03975 - ko00000 SNARE-like domain protein
HFLOMJMM_00629 1.52e-303 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HFLOMJMM_00630 1.31e-103 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
HFLOMJMM_00631 4.08e-88 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HFLOMJMM_00632 5.67e-157 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HFLOMJMM_00633 2.15e-267 coiA - - S ko:K06198 - ko00000 Competence protein
HFLOMJMM_00634 0.0 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HFLOMJMM_00635 2.51e-150 yjbH - - Q - - - Thioredoxin
HFLOMJMM_00636 9.06e-151 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
HFLOMJMM_00637 1.52e-198 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HFLOMJMM_00638 4.28e-225 yjbO 5.4.99.23 - G ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
HFLOMJMM_00641 0.0 - - - L ko:K07484 - ko00000 Transposase IS66 family
HFLOMJMM_00642 3.81e-88 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
HFLOMJMM_00644 6.84e-254 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
HFLOMJMM_00645 3.61e-209 rrmA 2.1.1.187 - H ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 Methyltransferase
HFLOMJMM_00646 2.64e-124 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HFLOMJMM_00647 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
HFLOMJMM_00648 4.47e-16 - - - S - - - Protein of unknown function (DUF4044)
HFLOMJMM_00649 1.6e-77 - - - - - - - -
HFLOMJMM_00650 1.5e-101 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
HFLOMJMM_00651 1.61e-224 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HFLOMJMM_00652 5.99e-74 ftsL - - D - - - Cell division protein FtsL
HFLOMJMM_00653 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
HFLOMJMM_00654 3.83e-230 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HFLOMJMM_00655 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HFLOMJMM_00656 2.16e-262 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HFLOMJMM_00657 7.77e-198 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HFLOMJMM_00658 0.0 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HFLOMJMM_00659 6.52e-289 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HFLOMJMM_00660 1.57e-92 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HFLOMJMM_00661 1.11e-54 ylmG - - S ko:K02221 - ko00000,ko02044 YGGT family
HFLOMJMM_00662 1.84e-190 ylmH - - S - - - S4 domain protein
HFLOMJMM_00663 6.11e-108 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
HFLOMJMM_00664 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HFLOMJMM_00665 5.69e-44 cspB - - K ko:K03704 - ko00000,ko03000 Cold shock protein
HFLOMJMM_00666 2.48e-129 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
HFLOMJMM_00667 1.54e-33 - - - - - - - -
HFLOMJMM_00668 3.4e-162 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HFLOMJMM_00669 1.63e-280 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
HFLOMJMM_00670 5.58e-76 XK27_04120 - - S - - - Putative amino acid metabolism
HFLOMJMM_00671 2.15e-286 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HFLOMJMM_00672 4.89e-160 pgm6 - - G - - - phosphoglycerate mutase
HFLOMJMM_00673 1.1e-156 - - - S - - - repeat protein
HFLOMJMM_00674 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HFLOMJMM_00675 3.64e-224 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HFLOMJMM_00676 6.48e-243 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HFLOMJMM_00677 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
HFLOMJMM_00678 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HFLOMJMM_00679 1.2e-114 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HFLOMJMM_00680 4.19e-286 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HFLOMJMM_00681 5.62e-224 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HFLOMJMM_00682 1.62e-183 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HFLOMJMM_00683 3.19e-283 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HFLOMJMM_00684 1.56e-255 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HFLOMJMM_00685 6.43e-05 cdaR_3 - - QT ko:K02647 - ko00000,ko03000 PucR C-terminal helix-turn-helix domain
HFLOMJMM_00686 6.84e-35 - - - KT ko:K02647 - ko00000,ko03000 Putative sugar diacid recognition
HFLOMJMM_00687 2.31e-281 yojA - - EG ko:K03299 - ko00000,ko02000 GntP family permease
HFLOMJMM_00688 1.73e-270 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
HFLOMJMM_00689 5.28e-76 - - - - - - - -
HFLOMJMM_00691 5.28e-254 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
HFLOMJMM_00692 4.37e-39 - - - - - - - -
HFLOMJMM_00693 2.71e-235 - - - I - - - Diacylglycerol kinase catalytic
HFLOMJMM_00694 9.99e-44 ykzG - - S - - - Belongs to the UPF0356 family
HFLOMJMM_00695 2.79e-107 - - - - - - - -
HFLOMJMM_00696 8.3e-134 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HFLOMJMM_00697 2.44e-267 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
HFLOMJMM_00698 2.31e-232 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Transketolase, C-terminal domain protein
HFLOMJMM_00699 1.34e-314 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HFLOMJMM_00700 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
HFLOMJMM_00701 2.87e-63 yktA - - S - - - Belongs to the UPF0223 family
HFLOMJMM_00702 2.12e-178 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the inositol monophosphatase superfamily
HFLOMJMM_00703 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
HFLOMJMM_00704 2.75e-286 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
HFLOMJMM_00705 3.83e-61 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
HFLOMJMM_00706 2.37e-129 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
HFLOMJMM_00707 3.05e-116 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HFLOMJMM_00708 1.56e-254 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
HFLOMJMM_00709 8.7e-141 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
HFLOMJMM_00710 2.47e-116 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
HFLOMJMM_00711 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
HFLOMJMM_00712 5.84e-203 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
HFLOMJMM_00713 1.44e-47 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
HFLOMJMM_00714 1.74e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HFLOMJMM_00715 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HFLOMJMM_00716 1.3e-210 - - - S - - - Tetratricopeptide repeat
HFLOMJMM_00717 4.94e-288 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HFLOMJMM_00718 5.54e-303 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HFLOMJMM_00719 5.06e-298 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HFLOMJMM_00720 2.01e-139 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
HFLOMJMM_00721 1.11e-78 - - - S - - - mazG nucleotide pyrophosphohydrolase
HFLOMJMM_00722 2.44e-20 - - - - - - - -
HFLOMJMM_00723 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HFLOMJMM_00724 0.0 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HFLOMJMM_00725 2.39e-226 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HFLOMJMM_00726 1.05e-201 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
HFLOMJMM_00727 5.25e-106 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
HFLOMJMM_00731 0.0 - - - S ko:K06919 - ko00000 Phage plasmid primase, P4
HFLOMJMM_00734 3.72e-111 - - - L - - - HNH nucleases
HFLOMJMM_00736 1.34e-103 terS - - L - - - Phage terminase, small subunit
HFLOMJMM_00737 0.0 terL - - S - - - overlaps another CDS with the same product name
HFLOMJMM_00739 9.18e-265 - - - S - - - Phage portal protein
HFLOMJMM_00740 0.0 - - - S ko:K06904 - ko00000 Caudovirus prohead serine protease
HFLOMJMM_00741 3.04e-100 - - - S - - - Transcriptional regulator, RinA family
HFLOMJMM_00742 6.69e-61 - - - S - - - Phage gp6-like head-tail connector protein
HFLOMJMM_00744 3.18e-167 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HFLOMJMM_00745 1.49e-272 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
HFLOMJMM_00746 2.52e-148 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HFLOMJMM_00747 2.7e-47 ynzC - - S - - - UPF0291 protein
HFLOMJMM_00748 1.6e-40 XK26_06720 - - S ko:K09976 - ko00000 Uncharacterised protein family (UPF0154)
HFLOMJMM_00749 1.84e-152 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
HFLOMJMM_00750 2.92e-182 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
HFLOMJMM_00751 6.79e-65 yazA - - L ko:K07461 - ko00000 GIY-YIG catalytic domain protein
HFLOMJMM_00752 8.74e-235 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HFLOMJMM_00753 3.54e-184 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
HFLOMJMM_00754 3.14e-197 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HFLOMJMM_00755 2.21e-167 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
HFLOMJMM_00756 7.32e-124 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HFLOMJMM_00757 0.0 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HFLOMJMM_00758 4.71e-112 - - - L ko:K07491 - ko00000 PFAM transposase IS200-family protein
HFLOMJMM_00759 6.92e-184 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HFLOMJMM_00760 2.03e-178 cdsA 2.7.7.41 - I ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
HFLOMJMM_00761 9.87e-300 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
HFLOMJMM_00762 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HFLOMJMM_00763 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HFLOMJMM_00764 7.73e-109 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
HFLOMJMM_00765 3.54e-276 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
HFLOMJMM_00766 5.93e-60 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
HFLOMJMM_00767 1.96e-65 ylxQ - - J - - - ribosomal protein
HFLOMJMM_00768 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HFLOMJMM_00769 1.38e-77 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HFLOMJMM_00770 1.48e-216 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HFLOMJMM_00771 4.14e-230 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
HFLOMJMM_00772 3.09e-85 - - - - - - - -
HFLOMJMM_00773 1.37e-248 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HFLOMJMM_00774 2.83e-118 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HFLOMJMM_00775 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
HFLOMJMM_00776 3.81e-274 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HFLOMJMM_00777 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HFLOMJMM_00778 4.55e-288 int7 - - L - - - Belongs to the 'phage' integrase family
HFLOMJMM_00779 1.7e-182 - - - - - - - -
HFLOMJMM_00780 4.29e-18 - - - - - - - -
HFLOMJMM_00781 2.44e-99 - - - - - - - -
HFLOMJMM_00782 5.09e-107 - - - - - - - -
HFLOMJMM_00783 2.6e-14 - - - K - - - Peptidase S24-like
HFLOMJMM_00784 1.21e-30 - - - K - - - Peptidase S24-like
HFLOMJMM_00785 0.0 pepD3 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HFLOMJMM_00786 3.16e-258 - - - C - - - Belongs to the LDH2 MDH2 oxidoreductase family
HFLOMJMM_00787 3.37e-222 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
HFLOMJMM_00789 3.36e-77 - - - - - - - -
HFLOMJMM_00790 2.15e-234 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
HFLOMJMM_00791 1.05e-168 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HFLOMJMM_00792 2.38e-72 - - - - - - - -
HFLOMJMM_00793 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HFLOMJMM_00794 5.38e-101 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HFLOMJMM_00795 2.03e-218 - - - G - - - Phosphotransferase enzyme family
HFLOMJMM_00796 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HFLOMJMM_00797 4.71e-112 - - - L ko:K07491 - ko00000 PFAM transposase IS200-family protein
HFLOMJMM_00798 1.01e-171 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HFLOMJMM_00799 0.0 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
HFLOMJMM_00800 1e-31 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
HFLOMJMM_00801 2.34e-92 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
HFLOMJMM_00802 6.44e-239 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HFLOMJMM_00803 6.2e-305 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
HFLOMJMM_00804 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
HFLOMJMM_00805 7.55e-123 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
HFLOMJMM_00806 4.86e-233 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HFLOMJMM_00807 6.39e-235 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
HFLOMJMM_00808 1.55e-109 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HFLOMJMM_00809 1.8e-81 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
HFLOMJMM_00810 2.66e-219 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HFLOMJMM_00811 3.71e-190 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
HFLOMJMM_00812 6.69e-238 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
HFLOMJMM_00813 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
HFLOMJMM_00814 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HFLOMJMM_00815 2.54e-266 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HFLOMJMM_00816 2.51e-280 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HFLOMJMM_00817 0.0 - - - S - - - Uncharacterised protein family (UPF0236)
HFLOMJMM_00818 1.23e-166 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
HFLOMJMM_00819 1.93e-203 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HFLOMJMM_00820 1.72e-305 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
HFLOMJMM_00821 5.59e-42 - - - S - - - Protein of unknown function (DUF2929)
HFLOMJMM_00822 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
HFLOMJMM_00823 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
HFLOMJMM_00824 9.26e-216 yitL - - S ko:K00243 - ko00000 S1 domain
HFLOMJMM_00825 4.23e-214 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
HFLOMJMM_00826 3.67e-86 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HFLOMJMM_00827 1.05e-181 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HFLOMJMM_00828 1.15e-136 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HFLOMJMM_00829 2.58e-165 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
HFLOMJMM_00830 3.23e-134 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HFLOMJMM_00831 8.62e-252 - - - S - - - Helix-turn-helix domain
HFLOMJMM_00832 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
HFLOMJMM_00833 1.81e-70 - - - M - - - Lysin motif
HFLOMJMM_00834 4.62e-154 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
HFLOMJMM_00835 1.49e-274 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
HFLOMJMM_00836 0.0 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
HFLOMJMM_00837 1.6e-54 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HFLOMJMM_00838 1.64e-301 XK27_05225 - - S - - - Tetratricopeptide repeat protein
HFLOMJMM_00839 1.8e-289 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HFLOMJMM_00840 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 ABC transporter, ATP-binding protein
HFLOMJMM_00841 3.61e-247 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HFLOMJMM_00842 4.1e-120 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HFLOMJMM_00843 2.59e-144 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
HFLOMJMM_00844 9.45e-198 WQ51_01275 - - S - - - EDD domain protein, DegV family
HFLOMJMM_00845 1.18e-221 - - - E - - - lipolytic protein G-D-S-L family
HFLOMJMM_00846 2.01e-141 ypmS - - S - - - Uncharacterized protein conserved in bacteria (DUF2140)
HFLOMJMM_00847 4.62e-48 yozE - - S - - - Belongs to the UPF0346 family
HFLOMJMM_00848 2.53e-207 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HFLOMJMM_00849 3.16e-184 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HFLOMJMM_00850 2.44e-210 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
HFLOMJMM_00851 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HFLOMJMM_00852 2.19e-218 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
HFLOMJMM_00853 1.9e-139 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HFLOMJMM_00854 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HFLOMJMM_00855 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HFLOMJMM_00856 3.56e-113 - - - F - - - NUDIX domain
HFLOMJMM_00857 1.81e-222 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
HFLOMJMM_00858 3.33e-244 - - - L - - - PFAM Integrase catalytic region
HFLOMJMM_00859 2.59e-89 - - - S - - - Belongs to the HesB IscA family
HFLOMJMM_00860 4.18e-43 - - - - - - - -
HFLOMJMM_00862 9.65e-120 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
HFLOMJMM_00863 1.15e-82 asp1 - - S - - - Asp23 family, cell envelope-related function
HFLOMJMM_00864 3.09e-35 - - - - - - - -
HFLOMJMM_00865 1.38e-125 - - - - - - - -
HFLOMJMM_00866 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
HFLOMJMM_00867 2.49e-235 - - - K ko:K02525 - ko00000,ko03000 Transcriptional regulator, LacI family
HFLOMJMM_00868 8.68e-257 gntP - - EG ko:K03299 - ko00000,ko02000 Gluconate
HFLOMJMM_00869 7.28e-305 int - - L ko:K06400 - ko00000 COG1961 Site-specific recombinases, DNA invertase Pin homologs
HFLOMJMM_00870 4.28e-192 - - - - - - - -
HFLOMJMM_00872 3.75e-98 - - - - - - - -
HFLOMJMM_00873 2.86e-93 - - - S - - - IrrE N-terminal-like domain
HFLOMJMM_00874 3.02e-62 - - - K - - - Helix-turn-helix domain
HFLOMJMM_00875 3.73e-44 - - - K - - - Helix-turn-helix XRE-family like proteins
HFLOMJMM_00876 1.1e-180 - - - K ko:K07741 - ko00000 BRO family, N-terminal domain
HFLOMJMM_00879 1.98e-44 - - - - - - - -
HFLOMJMM_00880 1.35e-05 - - - K - - - XRE family transcriptional regulator
HFLOMJMM_00884 1.03e-211 - - - L ko:K07455 - ko00000,ko03400 RecT family
HFLOMJMM_00885 2.65e-210 pi112 - - L - - - PDDEXK-like domain of unknown function (DUF3799)
HFLOMJMM_00886 1.65e-205 - - - L - - - Psort location Cytoplasmic, score
HFLOMJMM_00887 2.3e-78 - - - - - - - -
HFLOMJMM_00896 2.17e-10 - - - - - - - -
HFLOMJMM_00899 4.49e-102 - - - - - - - -
HFLOMJMM_00900 9.86e-200 - - - - - - - -
HFLOMJMM_00902 4.71e-112 - - - L ko:K07491 - ko00000 PFAM transposase IS200-family protein
HFLOMJMM_00903 2.71e-14 - - - - - - - -
HFLOMJMM_00904 1.51e-132 - - - L - - - HNH nucleases
HFLOMJMM_00905 1.1e-108 - - - L - - - Phage terminase, small subunit
HFLOMJMM_00907 1.59e-13 - - - - - - - -
HFLOMJMM_00908 0.0 - - - S - - - Phage Terminase
HFLOMJMM_00909 1.85e-283 - - - S - - - Phage portal protein
HFLOMJMM_00910 9.31e-166 - 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S14 family
HFLOMJMM_00911 3.68e-276 - - - S - - - Phage capsid family
HFLOMJMM_00912 4.41e-80 - - - S - - - Phage gp6-like head-tail connector protein
HFLOMJMM_00913 4.51e-77 - - - S - - - Phage head-tail joining protein
HFLOMJMM_00914 1.11e-92 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
HFLOMJMM_00915 3.7e-88 - - - S - - - Protein of unknown function (DUF806)
HFLOMJMM_00916 4.5e-174 - - - S - - - Phage tail tube protein
HFLOMJMM_00917 6.12e-83 - - - S - - - Phage tail assembly chaperone proteins, TAC
HFLOMJMM_00918 0.0 - - - L - - - Phage tail tape measure protein TP901
HFLOMJMM_00919 7.27e-207 - - - S - - - Phage tail protein
HFLOMJMM_00920 0.0 - - - M - - - Prophage endopeptidase tail
HFLOMJMM_00921 2.9e-23 spoIVFA - GT2,GT4 D ko:K05802,ko:K06401,ko:K20444,ko:K22051 - ko00000,ko01000,ko01005,ko02000 peptidase
HFLOMJMM_00925 6.49e-268 - - - - - - - -
HFLOMJMM_00928 9.71e-101 - - - - - - - -
HFLOMJMM_00930 4.85e-57 - - - - - - - -
HFLOMJMM_00931 6.74e-80 - - - S - - - COG5546 Small integral membrane protein
HFLOMJMM_00932 6.1e-247 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
HFLOMJMM_00933 4.71e-112 - - - L ko:K07491 - ko00000 PFAM transposase IS200-family protein
HFLOMJMM_00934 4.45e-47 - - - - - - - -
HFLOMJMM_00935 5.41e-73 - - - S - - - Mazg nucleotide pyrophosphohydrolase
HFLOMJMM_00936 1.31e-206 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
HFLOMJMM_00937 0.0 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HFLOMJMM_00938 2.68e-110 - - - - - - - -
HFLOMJMM_00939 5.12e-243 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
HFLOMJMM_00940 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
HFLOMJMM_00941 0.0 lacZ 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 -beta-galactosidase
HFLOMJMM_00942 8.36e-231 hepT 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
HFLOMJMM_00943 8.07e-204 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
HFLOMJMM_00944 4.7e-186 XK27_00940 3.5.1.9 - S ko:K07130 ko00380,ko00630,ko01100,map00380,map00630,map01100 ko00000,ko00001,ko00002,ko01000 Putative cyclase
HFLOMJMM_00945 7.22e-286 - 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
HFLOMJMM_00946 2.22e-168 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HFLOMJMM_00947 6.3e-292 mdtG2 - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
HFLOMJMM_00948 1.73e-215 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
HFLOMJMM_00949 2.48e-57 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HFLOMJMM_00952 8.1e-160 sdhB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
HFLOMJMM_00953 8.64e-196 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HFLOMJMM_00954 1.61e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Peroxiredoxin
HFLOMJMM_00955 0.0 - 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Thioredoxin domain
HFLOMJMM_00956 3.09e-209 - - - L ko:K07497 - ko00000 hmm pf00665
HFLOMJMM_00957 1.61e-163 - - - L - - - Helix-turn-helix domain
HFLOMJMM_00958 0.0 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HFLOMJMM_00959 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
HFLOMJMM_00960 1.89e-35 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
HFLOMJMM_00961 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HFLOMJMM_00962 8.53e-120 - - - - - - - -
HFLOMJMM_00963 4.1e-51 - - - - - - - -
HFLOMJMM_00964 6.28e-136 - - - K - - - DNA-templated transcription, initiation
HFLOMJMM_00965 7.59e-37 - - - - - - - -
HFLOMJMM_00966 2e-79 - - - L ko:K07491 - ko00000 PFAM transposase IS200-family protein
HFLOMJMM_00967 1.08e-293 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HFLOMJMM_00968 2.24e-123 - - - - - - - -
HFLOMJMM_00969 1.37e-90 - - - K - - - Transcriptional regulator, HxlR family
HFLOMJMM_00970 2.91e-230 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
HFLOMJMM_00971 1.31e-28 epsB - - M - - - biosynthesis protein
HFLOMJMM_00972 1.55e-224 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HFLOMJMM_00973 8.85e-208 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HFLOMJMM_00974 0.0 - - - S - - - Protein of unknown function (DUF2971)
HFLOMJMM_00975 0.0 - - - S - - - KAP family P-loop domain
HFLOMJMM_00976 0.0 - - - S ko:K07459 - ko00000 AAA domain, putative AbiEii toxin, Type IV TA system
HFLOMJMM_00977 1.93e-266 - - - L - - - DNA helicase
HFLOMJMM_00978 2.9e-295 - - - L - - - Integrase core domain
HFLOMJMM_00979 7.45e-181 - - - L - - - Bacterial dnaA protein
HFLOMJMM_00980 1.01e-203 - - - - - - - -
HFLOMJMM_00981 3.33e-244 - - - L - - - PFAM Integrase catalytic region
HFLOMJMM_00982 9.76e-93 - - - O - - - Preprotein translocase subunit SecB
HFLOMJMM_00983 1.49e-225 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine S-methyltransferase
HFLOMJMM_00984 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
HFLOMJMM_00986 3.07e-05 - - - K - - - sequence-specific DNA binding
HFLOMJMM_00987 4.51e-192 - - - S - - - Protein of unknown function (DUF3800)
HFLOMJMM_00989 0.0 snf - - KL - - - domain protein
HFLOMJMM_00990 1.77e-203 snf - - KL - - - domain protein
HFLOMJMM_00991 1.63e-187 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
HFLOMJMM_00992 7.33e-271 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HFLOMJMM_00993 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 Putative exonuclease SbcCD, C subunit
HFLOMJMM_00994 1.24e-136 - - - L - - - nuclease
HFLOMJMM_00995 0.0 XK27_00340 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
HFLOMJMM_00996 5.2e-89 - - - - - - - -
HFLOMJMM_00997 3.82e-133 - - - D ko:K04095 - ko00000,ko03036 Fic/DOC family
HFLOMJMM_00998 1.9e-165 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HFLOMJMM_00999 7.77e-196 - - - G - - - Belongs to the phosphoglycerate mutase family
HFLOMJMM_01000 7.82e-37 - - - - - - - -
HFLOMJMM_01001 9.88e-239 - - - - - - - -
HFLOMJMM_01003 0.0 - - - L ko:K07484 - ko00000 Transposase IS66 family
HFLOMJMM_01004 1.5e-85 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
HFLOMJMM_01006 5.8e-149 - - - I - - - Acid phosphatase homologues
HFLOMJMM_01007 0.0 agl 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 31 family
HFLOMJMM_01008 6.12e-296 - - - P - - - Chloride transporter, ClC family
HFLOMJMM_01009 8.1e-153 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HFLOMJMM_01010 3e-194 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
HFLOMJMM_01011 2.03e-182 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HFLOMJMM_01012 6.11e-68 - - - - - - - -
HFLOMJMM_01013 0.0 - - - S - - - SEC-C Motif Domain Protein
HFLOMJMM_01014 0.0 - - - L ko:K07484 - ko00000 Transposase IS66 family
HFLOMJMM_01015 1.01e-69 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
HFLOMJMM_01017 5.16e-115 - - - K ko:K21562 - ko00000,ko03000 Transcriptional regulator, Crp Fnr family
HFLOMJMM_01018 7.69e-100 - - - - - - - -
HFLOMJMM_01019 2.4e-231 - - - - - - - -
HFLOMJMM_01020 4.71e-112 - - - L ko:K07491 - ko00000 PFAM transposase IS200-family protein
HFLOMJMM_01021 3.84e-60 - - - L - - - transposase and inactivated derivatives, IS30 family
HFLOMJMM_01022 6.19e-163 - - - L - - - PFAM Integrase catalytic region
HFLOMJMM_01023 1.19e-05 - - - - - - - -
HFLOMJMM_01024 0.0 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HFLOMJMM_01025 6.83e-101 tnp2 - - L - - - PFAM Transposase, IS204 IS1001 IS1096 IS1165
HFLOMJMM_01026 1.77e-93 tnp2 - - L - - - PFAM Transposase, IS204 IS1001 IS1096 IS1165
HFLOMJMM_01027 1.65e-151 - - - L - - - PFAM Integrase catalytic region
HFLOMJMM_01028 4.74e-223 fecB - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
HFLOMJMM_01029 3.12e-176 fecE 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
HFLOMJMM_01030 4.18e-165 fecD - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HFLOMJMM_01031 1.21e-99 - - - S - - - Flavodoxin
HFLOMJMM_01032 8.67e-85 moaE 2.8.1.12 - H ko:K03635,ko:K21142 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 MoaE protein
HFLOMJMM_01033 4.04e-48 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 ThiS family
HFLOMJMM_01034 5.25e-279 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 Transporter, major facilitator family protein
HFLOMJMM_01035 3.34e-213 - - - H - - - geranyltranstransferase activity
HFLOMJMM_01036 2.71e-234 - - - - - - - -
HFLOMJMM_01037 2.45e-26 - - - - - - - -
HFLOMJMM_01038 7.45e-150 nreC - - K ko:K07696 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 PFAM regulatory protein LuxR
HFLOMJMM_01039 5.31e-242 nreB 2.7.13.3 - F ko:K07683 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Sensor histidine kinase
HFLOMJMM_01040 6.37e-60 - - - - - - - -
HFLOMJMM_01041 2.03e-136 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HFLOMJMM_01042 1.17e-110 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
HFLOMJMM_01043 1.27e-290 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 MoeA N-terminal region (domain I and II)
HFLOMJMM_01044 4.94e-109 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
HFLOMJMM_01045 2.54e-243 moeB 2.7.7.80 - H ko:K21029 ko04122,map04122 ko00000,ko00001,ko01000 ThiF family
HFLOMJMM_01046 0.0 narZ 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HFLOMJMM_01047 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 4Fe-4S dicluster domain
HFLOMJMM_01048 2.97e-130 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase molybdenum cofactor assembly chaperone
HFLOMJMM_01049 9.45e-168 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase
HFLOMJMM_01050 2.52e-302 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HFLOMJMM_01051 0.0 - - - L - - - Transposase
HFLOMJMM_01052 3.97e-198 - - - EG - - - EamA-like transporter family
HFLOMJMM_01053 1.15e-152 - - - L - - - Integrase
HFLOMJMM_01054 8.81e-205 rssA - - S - - - Phospholipase, patatin family
HFLOMJMM_01055 0.0 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
HFLOMJMM_01056 8.4e-259 xerS - - L - - - Belongs to the 'phage' integrase family
HFLOMJMM_01058 1.76e-94 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HFLOMJMM_01059 2.35e-101 - - - K - - - Transcriptional regulator, MarR family
HFLOMJMM_01060 4.83e-229 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HFLOMJMM_01061 2.51e-47 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
HFLOMJMM_01062 2.23e-209 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
HFLOMJMM_01063 7.69e-170 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
HFLOMJMM_01064 1.27e-288 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HFLOMJMM_01065 1.3e-99 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HFLOMJMM_01066 1.38e-98 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HFLOMJMM_01067 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
HFLOMJMM_01068 7.2e-185 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HFLOMJMM_01069 5.87e-181 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 alpha subunit
HFLOMJMM_01070 1.04e-172 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
HFLOMJMM_01079 1.57e-73 - - - - - - - -
HFLOMJMM_01080 5.47e-151 frnE 5.3.4.1 - Q ko:K01829 - ko00000,ko01000 DSBA-like thioredoxin domain
HFLOMJMM_01081 5.51e-213 - - - I - - - alpha/beta hydrolase fold
HFLOMJMM_01082 4.71e-112 - - - L ko:K07491 - ko00000 PFAM transposase IS200-family protein
HFLOMJMM_01083 3.7e-11 - - - K - - - Helix-turn-helix XRE-family like proteins
HFLOMJMM_01084 1.54e-05 - - - K - - - Helix-turn-helix XRE-family like proteins
HFLOMJMM_01085 6.4e-26 - - - S - - - Phage derived protein Gp49-like (DUF891)
HFLOMJMM_01086 3.01e-63 int2 - - L - - - Belongs to the 'phage' integrase family
HFLOMJMM_01088 1.94e-64 - - - S - - - Lipopolysaccharide assembly protein A domain
HFLOMJMM_01089 3.73e-203 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
HFLOMJMM_01090 1.38e-117 ntd 2.4.2.6 - F ko:K08728 ko00240,map00240 ko00000,ko00001,ko01000 Nucleoside
HFLOMJMM_01091 5.02e-29 - - - - - - - -
HFLOMJMM_01092 5.57e-214 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HFLOMJMM_01093 3.57e-150 - - - S - - - Protein of unknown function (DUF421)
HFLOMJMM_01094 2.7e-39 - - - S - - - Protein of unknown function (DUF3290)
HFLOMJMM_01095 5.07e-39 - - - S - - - Protein of unknown function (DUF3290)
HFLOMJMM_01096 7.11e-57 - - - S ko:K09790 - ko00000 Protein of unknown function (DUF454)
HFLOMJMM_01097 0.0 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HFLOMJMM_01098 0.0 - - - I - - - Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HFLOMJMM_01099 1.78e-204 endA - - V ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
HFLOMJMM_01100 0.0 yifK - - E ko:K03293 - ko00000 Amino acid permease
HFLOMJMM_01102 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HFLOMJMM_01103 3.41e-296 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
HFLOMJMM_01104 2.9e-158 - - - S - - - SNARE associated Golgi protein
HFLOMJMM_01105 0.0 uvrA2 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 excinuclease ABC, A subunit
HFLOMJMM_01106 1.27e-72 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HFLOMJMM_01107 7.82e-80 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HFLOMJMM_01108 3.39e-90 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HFLOMJMM_01109 2.92e-192 - - - S - - - DUF218 domain
HFLOMJMM_01110 0.0 ubiB - - S ko:K03688 - ko00000 ABC1 family
HFLOMJMM_01111 0.0 yhdP - - S - - - Transporter associated domain
HFLOMJMM_01112 1.68e-98 atkY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor CopY TcrY
HFLOMJMM_01113 2.6e-312 - - - U - - - Belongs to the major facilitator superfamily
HFLOMJMM_01114 1.35e-97 - - - S - - - UPF0756 membrane protein
HFLOMJMM_01115 1.42e-82 - - - S - - - Cupin domain
HFLOMJMM_01116 7.72e-114 - - - C - - - Flavodoxin
HFLOMJMM_01117 2.08e-208 rlrB - - K - - - LysR substrate binding domain protein
HFLOMJMM_01118 2.79e-225 yvgN - - C - - - Aldo keto reductase
HFLOMJMM_01119 1.02e-51 XK27_08630 - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
HFLOMJMM_01120 9.81e-314 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
HFLOMJMM_01121 0.0 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HFLOMJMM_01122 1.11e-123 - - - K - - - Acetyltransferase (GNAT) domain
HFLOMJMM_01123 5.98e-206 - - - S - - - Alpha beta hydrolase
HFLOMJMM_01124 9.18e-206 gspA - - M - - - family 8
HFLOMJMM_01125 1.29e-155 yagB - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
HFLOMJMM_01126 7.18e-126 - - - - - - - -
HFLOMJMM_01127 5.11e-208 - - - S - - - EDD domain protein, DegV family
HFLOMJMM_01128 0.0 FbpA - - K - - - Fibronectin-binding protein
HFLOMJMM_01129 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
HFLOMJMM_01130 1.93e-265 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarA family
HFLOMJMM_01131 7.11e-225 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
HFLOMJMM_01132 8.85e-97 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HFLOMJMM_01133 2.58e-85 esbA - - S - - - Family of unknown function (DUF5322)
HFLOMJMM_01134 7.66e-92 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease HI
HFLOMJMM_01135 6.84e-296 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
HFLOMJMM_01136 6.11e-111 - - - F ko:K03647 - ko00000 Belongs to the NrdI family
HFLOMJMM_01137 6.82e-74 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HFLOMJMM_01138 1.17e-135 ypsA - - S - - - Belongs to the UPF0398 family
HFLOMJMM_01139 1.21e-153 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HFLOMJMM_01140 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
HFLOMJMM_01141 2.42e-208 - - - EG - - - EamA-like transporter family
HFLOMJMM_01142 2.48e-161 dnaD - - L ko:K02086 - ko00000 DnaD domain protein
HFLOMJMM_01143 1.15e-115 ypmB - - S - - - Protein conserved in bacteria
HFLOMJMM_01144 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
HFLOMJMM_01145 1.09e-221 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 mevalonate kinase
HFLOMJMM_01146 1.74e-226 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
HFLOMJMM_01147 4.11e-274 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
HFLOMJMM_01148 1.31e-247 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HFLOMJMM_01149 8.22e-122 - - - S ko:K08996 - ko00000 Protein of unknown function (DUF1440)
HFLOMJMM_01150 0.0 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
HFLOMJMM_01151 1.12e-246 galR - - K ko:K02529 - ko00000,ko03000 Periplasmic binding protein-like domain
HFLOMJMM_01152 4.28e-102 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
HFLOMJMM_01153 1.7e-101 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
HFLOMJMM_01154 1.19e-229 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
HFLOMJMM_01155 4.38e-161 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 LrgB-like family
HFLOMJMM_01156 3.69e-87 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 LrgA family
HFLOMJMM_01157 2.9e-169 lytT - - K ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator receiver
HFLOMJMM_01158 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 LytS YhcK-type transmembrane receptor domain protein
HFLOMJMM_01159 3.63e-190 - - - O - - - Band 7 protein
HFLOMJMM_01160 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
HFLOMJMM_01161 4.21e-201 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
HFLOMJMM_01162 7.08e-52 - - - S - - - Cytochrome B5
HFLOMJMM_01163 6.38e-151 nreC - - K ko:K07696 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 PFAM regulatory protein LuxR
HFLOMJMM_01164 2e-207 - - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
HFLOMJMM_01165 1.18e-76 - - - S - - - Iron-sulfur cluster assembly protein
HFLOMJMM_01166 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
HFLOMJMM_01167 9.11e-106 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
HFLOMJMM_01168 2.43e-303 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HFLOMJMM_01169 2.11e-308 sufD - - O ko:K07033,ko:K09015 - ko00000 FeS assembly protein SufD
HFLOMJMM_01170 5.43e-185 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
HFLOMJMM_01171 9.89e-43 feoA - - P ko:K04758 - ko00000,ko02000 FeoA domain
HFLOMJMM_01172 0.0 feoB - - P ko:K04759 - ko00000,ko02000 transporter of a GTP-driven Fe(2 ) uptake system
HFLOMJMM_01173 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HFLOMJMM_01174 6.96e-201 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HFLOMJMM_01175 4.73e-85 yuxO - - Q - - - Thioesterase superfamily
HFLOMJMM_01176 3.51e-142 yvrI - - K ko:K03091,ko:K03093 - ko00000,ko03021 sigma factor activity
HFLOMJMM_01177 3.07e-265 - - - G - - - Transporter, major facilitator family protein
HFLOMJMM_01178 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
HFLOMJMM_01179 1.81e-146 - - - T ko:K10716 - ko00000,ko02000 Ion transport 2 domain protein
HFLOMJMM_01180 2.33e-103 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HFLOMJMM_01181 1e-290 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
HFLOMJMM_01182 3.2e-138 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
HFLOMJMM_01183 1.19e-259 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HFLOMJMM_01184 3.42e-233 rihA - - F ko:K01250 - ko00000,ko01000 Inosine-uridine preferring nucleoside hydrolase
HFLOMJMM_01186 0.0 - - - L - - - PLD-like domain
HFLOMJMM_01187 1.5e-48 higA - - K ko:K21498 - ko00000,ko02048 addiction module antidote protein HigA
HFLOMJMM_01188 0.0 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
HFLOMJMM_01189 6.57e-239 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
HFLOMJMM_01190 3.55e-231 - - - L - - - Belongs to the 'phage' integrase family
HFLOMJMM_01191 4.33e-146 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
HFLOMJMM_01192 6.46e-131 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
HFLOMJMM_01193 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
HFLOMJMM_01194 2.75e-105 - - - S - - - Protein of unknown function (DUF805)
HFLOMJMM_01195 1.26e-60 - - - - - - - -
HFLOMJMM_01196 0.0 nylA 3.5.1.4 - J ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 ko00000,ko00001,ko01000 Belongs to the amidase family
HFLOMJMM_01197 1.81e-41 - - - - - - - -
HFLOMJMM_01198 2.06e-125 - - - K - - - Acetyltransferase (GNAT) domain
HFLOMJMM_01199 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
HFLOMJMM_01200 8.65e-20 gntP - - EG ko:K03299 - ko00000,ko02000 Gluconate
HFLOMJMM_01201 1.5e-247 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
HFLOMJMM_01202 2.35e-106 - - - S - - - Bacteriophage holin family
HFLOMJMM_01204 2.78e-100 - - - - - - - -
HFLOMJMM_01207 6.49e-268 - - - - - - - -
HFLOMJMM_01211 8.21e-19 - - - LM - - - gp58-like protein
HFLOMJMM_01212 0.0 - - - S - - - Peptidase family M23
HFLOMJMM_01213 1.49e-222 - - - S - - - Phage tail protein
HFLOMJMM_01214 0.0 - - - D - - - domain protein
HFLOMJMM_01215 1.55e-122 - - - S - - - Phage tail assembly chaperone protein, TAC
HFLOMJMM_01216 2.24e-159 - - - - - - - -
HFLOMJMM_01217 5.74e-94 - - - - - - - -
HFLOMJMM_01218 5.18e-128 - - - - - - - -
HFLOMJMM_01219 3.92e-70 - - - - - - - -
HFLOMJMM_01220 1.8e-83 - - - S - - - Phage gp6-like head-tail connector protein
HFLOMJMM_01221 8.1e-261 gpG - - - - - - -
HFLOMJMM_01222 1e-138 - - - S - - - Domain of unknown function (DUF4355)
HFLOMJMM_01224 5.45e-231 - - - S - - - Phage Mu protein F like protein
HFLOMJMM_01225 0.0 - - - S - - - Phage portal protein, SPP1 Gp6-like
HFLOMJMM_01226 0.0 - - - S ko:K06909 - ko00000 Phage terminase, large subunit
HFLOMJMM_01228 1.14e-183 - - - K - - - Belongs to the N(4) N(6)-methyltransferase family
HFLOMJMM_01229 7.15e-95 - - - - - - - -
HFLOMJMM_01230 8.42e-163 - 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 sulfate reduction
HFLOMJMM_01232 4.49e-102 - - - - - - - -
HFLOMJMM_01235 2.17e-10 - - - - - - - -
HFLOMJMM_01244 2.3e-78 - - - - - - - -
HFLOMJMM_01245 1.65e-205 - - - L - - - Psort location Cytoplasmic, score
HFLOMJMM_01246 5.75e-196 pi112 - - L - - - PDDEXK-like domain of unknown function (DUF3799)
HFLOMJMM_01247 2.9e-228 - - - L ko:K07455 - ko00000,ko03400 RecT family
HFLOMJMM_01251 3.7e-25 - - - - - - - -
HFLOMJMM_01252 2.73e-181 - - - K ko:K07741 - ko00000 BRO family, N-terminal domain
HFLOMJMM_01253 2.72e-42 - - - K - - - Helix-turn-helix XRE-family like proteins
HFLOMJMM_01254 2.37e-95 - - - K - - - Cro/C1-type HTH DNA-binding domain
HFLOMJMM_01255 2.76e-108 - - - E - - - IrrE N-terminal-like domain
HFLOMJMM_01256 1.48e-66 - - - M - - - Host cell surface-exposed lipoprotein
HFLOMJMM_01257 2.86e-68 - - - - - - - -
HFLOMJMM_01258 1.66e-269 - - - L - - - Belongs to the 'phage' integrase family
HFLOMJMM_01259 3.03e-83 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HFLOMJMM_01260 0.0 - - - E ko:K03294 - ko00000 amino acid
HFLOMJMM_01261 5.46e-183 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
HFLOMJMM_01262 1.86e-119 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HFLOMJMM_01263 3.74e-53 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
HFLOMJMM_01264 1.21e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
HFLOMJMM_01265 0.0 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HFLOMJMM_01266 4.23e-76 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HFLOMJMM_01267 4.22e-293 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HFLOMJMM_01268 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
HFLOMJMM_01269 1.57e-168 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HFLOMJMM_01270 1.81e-50 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
HFLOMJMM_01271 1.41e-242 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HFLOMJMM_01272 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HFLOMJMM_01273 0.0 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
HFLOMJMM_01274 1.05e-77 yloU - - S - - - Asp23 family, cell envelope-related function
HFLOMJMM_01275 1.1e-34 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
HFLOMJMM_01276 6.95e-159 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
HFLOMJMM_01277 5.46e-152 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
HFLOMJMM_01278 1.59e-213 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HFLOMJMM_01279 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
HFLOMJMM_01280 4.45e-170 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
HFLOMJMM_01281 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HFLOMJMM_01282 1.81e-225 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HFLOMJMM_01283 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HFLOMJMM_01284 1.97e-276 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HFLOMJMM_01285 6.66e-43 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HFLOMJMM_01286 4.37e-148 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
HFLOMJMM_01287 9e-72 - - - - - - - -
HFLOMJMM_01288 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
HFLOMJMM_01289 6.71e-102 argR2 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
HFLOMJMM_01290 1.69e-192 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
HFLOMJMM_01291 3.59e-207 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
HFLOMJMM_01292 9.86e-59 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HFLOMJMM_01293 5.04e-283 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HFLOMJMM_01294 2.71e-200 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HFLOMJMM_01295 9.11e-92 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HFLOMJMM_01296 2.27e-93 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
HFLOMJMM_01297 6.38e-159 - - - J - - - 2'-5' RNA ligase superfamily
HFLOMJMM_01298 2.83e-261 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
HFLOMJMM_01299 1.63e-171 - - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HFLOMJMM_01300 5.07e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
HFLOMJMM_01301 8.76e-73 ysxB - - J ko:K07584 - ko00000 Cysteine protease Prp
HFLOMJMM_01302 2.68e-67 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
HFLOMJMM_01303 1.99e-146 - - - K - - - Transcriptional regulator
HFLOMJMM_01306 3.61e-117 - - - S - - - Protein conserved in bacteria
HFLOMJMM_01307 2.07e-239 - - - - - - - -
HFLOMJMM_01308 8.42e-204 - - - - - - - -
HFLOMJMM_01309 7.62e-68 yitW - - S - - - Iron-sulfur cluster assembly protein
HFLOMJMM_01310 6.94e-132 msrA 1.8.4.11 - C ko:K07304 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HFLOMJMM_01311 1.51e-200 - - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
HFLOMJMM_01312 1.28e-18 - - - - - - - -
HFLOMJMM_01313 1.31e-286 araT 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HFLOMJMM_01314 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HFLOMJMM_01315 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
HFLOMJMM_01316 1.06e-228 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HFLOMJMM_01317 1.18e-30 - - - S - - - Protein of unknown function (DUF3042)
HFLOMJMM_01318 2.67e-88 yqhL - - P - - - Rhodanese-like protein
HFLOMJMM_01319 2.51e-235 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
HFLOMJMM_01320 7.07e-48 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
HFLOMJMM_01321 1.44e-148 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Peptidase, S54 family
HFLOMJMM_01322 9.73e-132 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HFLOMJMM_01323 1.53e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
HFLOMJMM_01324 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
HFLOMJMM_01325 0.0 - - - S - - - membrane
HFLOMJMM_01326 4.64e-92 yneR - - S - - - Belongs to the HesB IscA family
HFLOMJMM_01327 6.08e-102 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HFLOMJMM_01328 2.06e-152 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
HFLOMJMM_01329 6.17e-151 - - - M - - - PFAM NLP P60 protein
HFLOMJMM_01330 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HFLOMJMM_01331 3.66e-252 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HFLOMJMM_01332 4.77e-77 yodB - - K - - - Transcriptional regulator, HxlR family
HFLOMJMM_01333 3.75e-119 XK27_09705 - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
HFLOMJMM_01334 6.64e-187 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HFLOMJMM_01335 1.07e-61 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
HFLOMJMM_01336 9.55e-216 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HFLOMJMM_01337 5.74e-94 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
HFLOMJMM_01338 1.84e-298 - - - V - - - MatE
HFLOMJMM_01339 0.0 potE - - E - - - Amino Acid
HFLOMJMM_01340 0.0 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HFLOMJMM_01341 1.38e-155 csrR - - K - - - response regulator
HFLOMJMM_01342 7.21e-39 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
HFLOMJMM_01343 1.01e-129 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
HFLOMJMM_01344 1.75e-276 ylbM - - S - - - Belongs to the UPF0348 family
HFLOMJMM_01345 9.84e-183 yqeM - - Q - - - Methyltransferase
HFLOMJMM_01346 2.3e-80 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HFLOMJMM_01347 1.07e-147 yqeK - - H - - - Hydrolase, HD family
HFLOMJMM_01348 4.36e-161 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HFLOMJMM_01349 5.4e-63 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein
HFLOMJMM_01350 1.9e-279 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
HFLOMJMM_01351 1.91e-125 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
HFLOMJMM_01352 5.46e-74 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HFLOMJMM_01353 1.82e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
HFLOMJMM_01354 2.15e-110 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HFLOMJMM_01355 2.57e-223 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
HFLOMJMM_01356 2.42e-300 dnaB - - L ko:K03346 - ko00000,ko03032 replication initiation and membrane attachment
HFLOMJMM_01357 2.82e-105 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HFLOMJMM_01358 5.5e-134 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HFLOMJMM_01359 8.18e-206 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HFLOMJMM_01360 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HFLOMJMM_01361 5.87e-155 - - - S - - - Protein of unknown function (DUF1275)
HFLOMJMM_01362 4.56e-154 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
HFLOMJMM_01363 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
HFLOMJMM_01364 3.43e-154 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HFLOMJMM_01365 2.95e-75 ytpP - - CO - - - Thioredoxin
HFLOMJMM_01366 2.27e-75 - - - S - - - Small secreted protein
HFLOMJMM_01367 1.53e-216 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
HFLOMJMM_01368 5.08e-237 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
HFLOMJMM_01369 0.0 tagE3 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
HFLOMJMM_01370 0.0 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HFLOMJMM_01371 0.0 - - - A ko:K12092 ko05120,map05120 ko00000,ko00001,ko00002,ko02044 chlorophyll binding
HFLOMJMM_01372 1.24e-233 - - - S - - - YSIRK type signal peptide
HFLOMJMM_01373 4.53e-158 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HFLOMJMM_01374 2.95e-282 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
HFLOMJMM_01375 1.39e-177 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HFLOMJMM_01376 1.49e-102 hit - - FG ko:K02503 - ko00000,ko04147 histidine triad
HFLOMJMM_01378 3.01e-178 prsA 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HFLOMJMM_01379 0.0 yhaN - - L - - - AAA domain
HFLOMJMM_01380 4.1e-295 yhaO - - L ko:K03547 - ko00000,ko03400 Ser Thr phosphatase family protein
HFLOMJMM_01381 3.9e-79 yheA - - S - - - Belongs to the UPF0342 family
HFLOMJMM_01382 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
HFLOMJMM_01383 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
HFLOMJMM_01384 1.51e-194 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
HFLOMJMM_01385 4.93e-216 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
HFLOMJMM_01387 1.49e-54 - - - - - - - -
HFLOMJMM_01388 4.61e-61 - - - - - - - -
HFLOMJMM_01389 5.66e-278 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 dihydropteroate synthase
HFLOMJMM_01390 8.88e-138 folQ 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Ham1 family
HFLOMJMM_01391 5.72e-301 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
HFLOMJMM_01392 1.17e-136 folE 2.7.6.3, 3.5.4.16 - F ko:K00950,ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase 1
HFLOMJMM_01393 4.05e-124 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
HFLOMJMM_01394 1.22e-74 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HFLOMJMM_01395 5.82e-96 - - - - - - - -
HFLOMJMM_01397 9.17e-59 - - - - - - - -
HFLOMJMM_01398 2.21e-155 XK27_07085 - - S ko:K07052 - ko00000 CAAX protease self-immunity
HFLOMJMM_01399 1.52e-43 - - - - - - - -
HFLOMJMM_01400 8.45e-210 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HFLOMJMM_01401 2.63e-240 rbsR - - K ko:K02529 - ko00000,ko03000 Periplasmic binding proteins and sugar binding domain of LacI family
HFLOMJMM_01402 5.33e-147 - - - - - - - -
HFLOMJMM_01403 3.06e-150 dgk2 - - F - - - deoxynucleoside kinase
HFLOMJMM_01404 9.46e-242 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HFLOMJMM_01405 5.35e-113 - - - T - - - Belongs to the universal stress protein A family
HFLOMJMM_01406 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
HFLOMJMM_01407 9.07e-199 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HFLOMJMM_01408 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
HFLOMJMM_01409 8.74e-57 - - - - - - - -
HFLOMJMM_01410 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
HFLOMJMM_01411 9.47e-281 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HFLOMJMM_01412 4.49e-130 tag1 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
HFLOMJMM_01413 7.96e-41 - - - - - - - -
HFLOMJMM_01414 0.0 - - - EGP - - - Major Facilitator
HFLOMJMM_01415 1.25e-111 perR - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
HFLOMJMM_01416 8.53e-304 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
HFLOMJMM_01417 2.01e-134 - - - V - - - VanZ like family
HFLOMJMM_01418 7.03e-33 - - - - - - - -
HFLOMJMM_01419 2.05e-110 - - - S - - - Short repeat of unknown function (DUF308)
HFLOMJMM_01420 7.91e-104 - - - S - - - Psort location Cytoplasmic, score
HFLOMJMM_01421 0.0 umuC - - L ko:K03502 - ko00000,ko03400 impB/mucB/samB family C-terminal domain
HFLOMJMM_01422 4.63e-101 hsp - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
HFLOMJMM_01423 2.42e-201 yeaE - - S - - - Aldo keto
HFLOMJMM_01424 2.29e-309 - 1.3.1.1 - C ko:K17723 ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100 ko00000,ko00001,ko00002,ko01000 4Fe-4S dicluster domain
HFLOMJMM_01425 4.87e-299 - 1.3.1.1 - E ko:K17722 ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
HFLOMJMM_01426 4.36e-194 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
HFLOMJMM_01427 2.13e-142 - - - M - - - LysM domain protein
HFLOMJMM_01428 0.0 - - - EP - - - Psort location Cytoplasmic, score
HFLOMJMM_01429 1.32e-131 - - - M - - - LysM domain protein
HFLOMJMM_01430 7.9e-214 - - - O - - - Uncharacterized protein family (UPF0051)
HFLOMJMM_01431 1.37e-144 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HFLOMJMM_01432 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
HFLOMJMM_01433 9.83e-316 lmrB - - U ko:K18926 - ko00000,ko00002,ko02000 Belongs to the major facilitator superfamily
HFLOMJMM_01434 9.73e-132 - - - K - - - Acetyltransferase (GNAT) domain
HFLOMJMM_01446 1.97e-53 - - - S - - - Protein of unknown function (DUF1797)
HFLOMJMM_01447 8e-230 mprF - - I ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HFLOMJMM_01448 4.82e-254 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
HFLOMJMM_01449 6.85e-295 pimB 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
HFLOMJMM_01450 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HFLOMJMM_01451 3.69e-54 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
HFLOMJMM_01452 9.69e-38 - - - - - - - -
HFLOMJMM_01453 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
HFLOMJMM_01454 1.56e-130 - - - S - - - Pfam:DUF3816
HFLOMJMM_01455 9.48e-183 - - - G - - - MucBP domain
HFLOMJMM_01456 1.27e-151 - - - - - - - -
HFLOMJMM_01457 4.04e-205 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HFLOMJMM_01458 1.45e-85 - - - K - - - Transcriptional regulator, GntR family
HFLOMJMM_01459 6.81e-221 - 3.2.1.23, 3.2.1.89 - G ko:K01190,ko:K01224 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 arabinogalactan endo-1,4-beta-galactosidase activity
HFLOMJMM_01460 0.0 ganB 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
HFLOMJMM_01461 8.12e-64 - - - S - - - dextransucrase activity
HFLOMJMM_01462 1.45e-57 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
HFLOMJMM_01463 1.08e-209 - - - L ko:K07497 - ko00000 hmm pf00665
HFLOMJMM_01464 2.05e-72 - - - L - - - Helix-turn-helix domain
HFLOMJMM_01465 2.09e-41 - - - L - - - Helix-turn-helix domain
HFLOMJMM_01466 2.33e-316 - - - L - - - Transposase
HFLOMJMM_01467 1.21e-35 - - - L - - - Transposase
HFLOMJMM_01468 9.89e-76 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
HFLOMJMM_01469 5.96e-125 - - - L ko:K07483,ko:K07497 - ko00000 Helix-turn-helix domain
HFLOMJMM_01470 7.81e-148 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
HFLOMJMM_01472 0.0 - 2.4.1.5 GH13 G ko:K00689 ko00500,ko02020,map00500,map02020 ko00000,ko00001,ko01000 Glycosyl hydrolase family 70
HFLOMJMM_01473 7.03e-156 p75 - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
HFLOMJMM_01474 0.0 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HFLOMJMM_01475 4.71e-112 - - - L ko:K07491 - ko00000 PFAM transposase IS200-family protein
HFLOMJMM_01476 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HFLOMJMM_01477 7.37e-300 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
HFLOMJMM_01478 0.0 - - - S - - - Psort location CytoplasmicMembrane, score
HFLOMJMM_01479 5.17e-252 yueF - - S - - - AI-2E family transporter
HFLOMJMM_01480 1.11e-190 - - - S ko:K21471 - ko00000,ko01000,ko01002,ko01011 dextransucrase activity
HFLOMJMM_01481 4.77e-289 - - - S - - - Uncharacterised protein family (UPF0236)
HFLOMJMM_01482 2.43e-156 - - - L - - - PFAM Integrase catalytic region
HFLOMJMM_01483 1.21e-137 - - - L - - - Helix-turn-helix domain
HFLOMJMM_01484 3.07e-102 - - - L ko:K07497 - ko00000 hmm pf00665
HFLOMJMM_01485 1.23e-171 - - - O - - - Bacterial dnaA protein
HFLOMJMM_01486 6.69e-304 - - - L - - - Integrase core domain
HFLOMJMM_01487 4.14e-230 - - - M - - - Glycosyltransferase like family 2
HFLOMJMM_01488 3.2e-68 - - - - - - - -
HFLOMJMM_01489 1.51e-204 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NLP P60 protein
HFLOMJMM_01490 1.48e-242 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NLP P60 protein
HFLOMJMM_01491 4.71e-112 - - - L ko:K07491 - ko00000 PFAM transposase IS200-family protein
HFLOMJMM_01492 8.56e-236 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NLP P60 protein
HFLOMJMM_01493 2.11e-250 - - - S - - - enterobacterial common antigen metabolic process
HFLOMJMM_01494 3.11e-248 - - - M - - - transferase activity, transferring glycosyl groups
HFLOMJMM_01495 1.23e-255 - - GT4 M ko:K02840 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 Glycosyl transferases group 1
HFLOMJMM_01496 0.0 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
HFLOMJMM_01497 1.82e-137 - - - M - - - biosynthesis protein
HFLOMJMM_01498 2.22e-276 cps3F - - - - - - -
HFLOMJMM_01499 3.84e-282 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
HFLOMJMM_01500 3.06e-157 - - - M - - - Bacterial sugar transferase
HFLOMJMM_01501 5.87e-227 yfdH - GT2 M ko:K12999 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
HFLOMJMM_01502 2.95e-193 cps1D - - M - - - Domain of unknown function (DUF4422)
HFLOMJMM_01503 6.84e-183 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
HFLOMJMM_01504 6.21e-43 - - - - - - - -
HFLOMJMM_01505 8.85e-47 - - - S - - - Protein of unknown function (DUF2922)
HFLOMJMM_01506 9.09e-204 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
HFLOMJMM_01507 0.0 potE - - E - - - Amino Acid
HFLOMJMM_01508 0.0 arcD - - E ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
HFLOMJMM_01509 5.05e-283 arcT - - E - - - Aminotransferase
HFLOMJMM_01510 1e-215 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
HFLOMJMM_01511 1.64e-103 ykuP - - C ko:K03839 - ko00000 Flavodoxin
HFLOMJMM_01512 8.59e-98 gtcA - - S - - - Teichoic acid glycosylation protein
HFLOMJMM_01513 4.07e-72 - - - - - - - -
HFLOMJMM_01514 6.52e-270 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HFLOMJMM_01516 3.45e-300 yfmL - - L - - - DEAD DEAH box helicase
HFLOMJMM_01517 1.31e-245 mocA - - S - - - Oxidoreductase
HFLOMJMM_01518 7.97e-82 - - - S - - - Domain of unknown function (DUF4828)
HFLOMJMM_01519 1.66e-142 - 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
HFLOMJMM_01520 2.64e-213 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
HFLOMJMM_01521 0.0 gshA 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
HFLOMJMM_01522 1.32e-255 - - - S - - - Protein of unknown function (DUF3114)
HFLOMJMM_01523 3.32e-107 yjcF 3.5.4.33, 4.4.1.8 - K ko:K02348,ko:K07000,ko:K11991,ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007,ko03016 protein acetylation
HFLOMJMM_01524 1.59e-153 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
HFLOMJMM_01525 7.31e-27 - - - - - - - -
HFLOMJMM_01526 2.44e-125 - - - K - - - Acetyltransferase (GNAT) family
HFLOMJMM_01527 2.57e-103 - - - K - - - LytTr DNA-binding domain
HFLOMJMM_01528 4.56e-99 - - - S - - - Protein of unknown function (DUF3021)
HFLOMJMM_01529 1.22e-218 - 3.2.1.96, 3.5.1.28 GH73 M ko:K01227,ko:K01447,ko:K13714,ko:K13731 ko00511,ko05100,map00511,map05100 ko00000,ko00001,ko01000 N-acetylmuramoyl-L-alanine amidase
HFLOMJMM_01530 4.43e-100 XK27_00915 - - C - - - Luciferase-like monooxygenase
HFLOMJMM_01531 1.04e-168 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HFLOMJMM_01532 1.85e-109 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Methyltransferase
HFLOMJMM_01533 3.87e-161 pnb - - C - - - nitroreductase
HFLOMJMM_01534 5.22e-120 - - - - - - - -
HFLOMJMM_01535 2.89e-110 yvbK - - K - - - GNAT family
HFLOMJMM_01536 0.0 - 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 pyridine nucleotide-disulfide oxidoreductase
HFLOMJMM_01537 8.89e-269 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
HFLOMJMM_01538 2.27e-62 - - - S - - - PD-(D/E)XK nuclease family transposase
HFLOMJMM_01539 3.01e-92 - - - S - - - PFAM Archaeal ATPase
HFLOMJMM_01540 5.76e-134 - - - S - - - PFAM Archaeal ATPase
HFLOMJMM_01541 0.0 XK27_08510 - - L - - - Type III restriction protein res subunit
HFLOMJMM_01542 1.6e-69 - - - - - - - -
HFLOMJMM_01543 9.52e-204 - - - V ko:K11050 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HFLOMJMM_01544 8.27e-189 cylB - - V ko:K11051 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 type transporter
HFLOMJMM_01545 3.2e-100 - - - K - - - LytTr DNA-binding domain
HFLOMJMM_01546 9.77e-80 - - - S - - - Protein of unknown function (DUF3021)
HFLOMJMM_01548 6.17e-236 - - - L - - - Plasmid pRiA4b ORF-3-like protein
HFLOMJMM_01550 2.7e-145 fnr - - K ko:K21562 - ko00000,ko03000 Transcriptional regulator, Crp Fnr family
HFLOMJMM_01551 3.54e-128 dpsB - - P - - - Belongs to the Dps family
HFLOMJMM_01552 2.79e-49 copZ - - P ko:K07213 ko04978,map04978 ko00000,ko00001 PFAM Heavy metal transport detoxification protein
HFLOMJMM_01553 2.66e-110 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 E1-E2 ATPase
HFLOMJMM_01554 2.74e-246 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 E1-E2 ATPase
HFLOMJMM_01555 8.72e-50 - - - F - - - NUDIX domain
HFLOMJMM_01556 0.0 - - - L - - - PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HFLOMJMM_01557 2.66e-117 entB - - Q - - - Isochorismatase family
HFLOMJMM_01558 0.0 - 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 EcoEI R protein C-terminal
HFLOMJMM_01559 1.89e-230 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
HFLOMJMM_01560 1.68e-228 - - - L - - - Belongs to the 'phage' integrase family
HFLOMJMM_01561 3.62e-250 - - - V - - - Type I restriction modification DNA specificity domain
HFLOMJMM_01562 0.0 - 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
HFLOMJMM_01563 1.83e-302 - - - - - - - -
HFLOMJMM_01564 0.0 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HFLOMJMM_01566 5.72e-239 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
HFLOMJMM_01567 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HFLOMJMM_01568 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HFLOMJMM_01569 9.59e-67 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HFLOMJMM_01570 1.91e-261 camS - - S - - - sex pheromone
HFLOMJMM_01571 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HFLOMJMM_01572 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
HFLOMJMM_01573 3.24e-272 purK2 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HFLOMJMM_01574 2.36e-131 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HFLOMJMM_01575 3.07e-149 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
HFLOMJMM_01576 7.72e-181 budC 1.1.1.304, 1.1.1.76 - IQ ko:K03366 ko00650,map00650 ko00000,ko00001,ko01000 reductase
HFLOMJMM_01577 3.94e-85 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
HFLOMJMM_01578 2.27e-103 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HFLOMJMM_01579 7.76e-185 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HFLOMJMM_01580 3.51e-182 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HFLOMJMM_01581 1.1e-200 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HFLOMJMM_01582 2.21e-189 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HFLOMJMM_01583 8.08e-83 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
HFLOMJMM_01584 2.19e-220 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HFLOMJMM_01585 1.62e-83 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HFLOMJMM_01586 1.54e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HFLOMJMM_01587 5.79e-21 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
HFLOMJMM_01588 2.41e-45 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HFLOMJMM_01589 4.52e-161 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HFLOMJMM_01590 2.88e-306 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HFLOMJMM_01591 6.05e-93 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
HFLOMJMM_01592 5.94e-34 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
HFLOMJMM_01593 5.95e-112 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HFLOMJMM_01594 5.03e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HFLOMJMM_01595 2.6e-124 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HFLOMJMM_01596 1.54e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HFLOMJMM_01597 7.42e-125 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HFLOMJMM_01598 2.58e-65 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HFLOMJMM_01599 3.62e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HFLOMJMM_01600 1.1e-55 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HFLOMJMM_01601 5.49e-38 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
HFLOMJMM_01602 1.96e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HFLOMJMM_01603 9.81e-157 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HFLOMJMM_01604 4.36e-70 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HFLOMJMM_01605 5.72e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HFLOMJMM_01606 1.16e-203 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HFLOMJMM_01607 3.61e-61 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HFLOMJMM_01608 6.64e-139 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
HFLOMJMM_01609 5.45e-153 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HFLOMJMM_01610 1.28e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
HFLOMJMM_01611 1.1e-255 - - - L - - - Transposase
HFLOMJMM_01612 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HFLOMJMM_01613 2.06e-108 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HFLOMJMM_01614 3.56e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HFLOMJMM_01615 1.44e-155 comC 3.4.23.43 - NOU ko:K02236 - ko00000,ko00002,ko01000,ko02044 Bacterial Peptidase A24 N-terminal domain
HFLOMJMM_01616 3.31e-263 - - - - - - - -
HFLOMJMM_01617 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HFLOMJMM_01618 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HFLOMJMM_01619 2.09e-143 - - - K - - - Bacterial regulatory proteins, tetR family
HFLOMJMM_01620 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HFLOMJMM_01621 1.39e-101 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
HFLOMJMM_01622 1.8e-249 adhP 1.1.1.1 - C ko:K00001,ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
HFLOMJMM_01623 7.53e-191 - - - S ko:K06889 - ko00000 Hydrolases of the alpha beta superfamily
HFLOMJMM_01629 7.78e-150 dgk2 - - F - - - deoxynucleoside kinase
HFLOMJMM_01630 4.71e-112 - - - L ko:K07491 - ko00000 PFAM transposase IS200-family protein
HFLOMJMM_01631 0.0 lysP - - E ko:K03293,ko:K11733 - ko00000,ko02000 amino acid
HFLOMJMM_01632 8.71e-07 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
HFLOMJMM_01633 2.79e-153 - - - I - - - phosphatase
HFLOMJMM_01634 2.59e-107 - - - S - - - Threonine/Serine exporter, ThrE
HFLOMJMM_01635 7.95e-171 - - - S - - - Putative threonine/serine exporter
HFLOMJMM_01636 2.17e-43 cspC - - K ko:K03704 - ko00000,ko03000 Cold shock protein
HFLOMJMM_01637 2.32e-161 mntR - - K ko:K03709 - ko00000,ko03000 iron dependent repressor
HFLOMJMM_01638 1.72e-213 - - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
HFLOMJMM_01639 3.11e-153 - - - S - - - membrane
HFLOMJMM_01640 4.71e-142 - - - S - - - VIT family
HFLOMJMM_01641 4.83e-108 - - - T - - - Belongs to the universal stress protein A family
HFLOMJMM_01642 1.39e-173 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HFLOMJMM_01643 9.45e-196 peb1A - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HFLOMJMM_01644 5.24e-143 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HFLOMJMM_01645 3.65e-141 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HFLOMJMM_01646 8.11e-282 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
HFLOMJMM_01647 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HFLOMJMM_01648 8.46e-77 - - - - - - - -
HFLOMJMM_01649 5.33e-98 - - - K - - - MerR HTH family regulatory protein
HFLOMJMM_01650 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
HFLOMJMM_01651 6.51e-161 - - - S - - - Domain of unknown function (DUF4811)
HFLOMJMM_01652 3.34e-212 yjbO 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
HFLOMJMM_01654 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HFLOMJMM_01655 4.55e-121 - 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 DJ-1/PfpI family
HFLOMJMM_01656 1.16e-242 - - - I - - - Alpha beta
HFLOMJMM_01657 0.0 qacA - - EGP - - - Major Facilitator
HFLOMJMM_01658 2.82e-154 - 3.2.2.27 - L ko:K21929 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Uracil-DNA glycosylase
HFLOMJMM_01659 0.0 - - - S - - - Putative threonine/serine exporter
HFLOMJMM_01660 5.08e-205 - - - K - - - LysR family
HFLOMJMM_01661 0.0 citP - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
HFLOMJMM_01662 0.0 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
HFLOMJMM_01663 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HFLOMJMM_01664 0.0 mleS 1.1.1.38, 4.1.1.101 - C ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme
HFLOMJMM_01665 1.3e-206 mleR - - K - - - LysR family
HFLOMJMM_01666 8.22e-144 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HFLOMJMM_01667 9.87e-266 adh 1.1.1.1 - C ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Zinc-binding alcohol dehydrogenase family protein
HFLOMJMM_01668 0.0 - - - L - - - PFAM plasmid pRiA4b ORF-3 family protein
HFLOMJMM_01669 0.0 - - - S ko:K13730 ko05100,map05100 ko00000,ko00001 Uncharacterized protein conserved in bacteria (DUF2252)
HFLOMJMM_01670 1.19e-31 - - - - - - - -
HFLOMJMM_01671 8.05e-259 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
HFLOMJMM_01672 5.36e-97 - - - - - - - -
HFLOMJMM_01673 2.79e-294 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
HFLOMJMM_01674 1.43e-180 - - - V - - - Beta-lactamase enzyme family
HFLOMJMM_01675 0.0 gtfA 2.4.1.7 GH13 G ko:K00690 ko00500,map00500 ko00000,ko00001,ko01000 Sucrose glucosyltransferase
HFLOMJMM_01676 5.43e-276 - - - EGP - - - Transporter, major facilitator family protein
HFLOMJMM_01677 0.0 arcT - - E - - - Dipeptidase
HFLOMJMM_01678 0.0 arcD - - S - - - C4-dicarboxylate anaerobic carrier
HFLOMJMM_01679 1.56e-229 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Peroxidase
HFLOMJMM_01680 9.01e-132 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
HFLOMJMM_01681 3.74e-212 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
HFLOMJMM_01682 6.66e-177 - - - I - - - alpha/beta hydrolase fold
HFLOMJMM_01683 2.95e-157 - - - S - - - Conserved hypothetical protein 698
HFLOMJMM_01684 9.06e-125 - - - S - - - NADPH-dependent FMN reductase
HFLOMJMM_01685 1.13e-217 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
HFLOMJMM_01686 9.78e-231 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
HFLOMJMM_01687 4.85e-296 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
HFLOMJMM_01688 1.13e-108 - - - Q - - - Methyltransferase
HFLOMJMM_01689 2.8e-152 ktrA - - P ko:K03499 - ko00000,ko02000 domain protein
HFLOMJMM_01690 4.98e-307 ktrB - - P ko:K03498 - ko00000,ko02000 Potassium uptake protein
HFLOMJMM_01691 0.0 mycA 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
HFLOMJMM_01692 3.28e-180 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
HFLOMJMM_01693 1.85e-288 - - - G - - - Glycosyl hydrolases family 8
HFLOMJMM_01694 2.22e-313 - - - M - - - Glycosyl transferase
HFLOMJMM_01695 6.17e-202 - - - - - - - -
HFLOMJMM_01696 8.65e-162 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
HFLOMJMM_01697 3.14e-177 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HFLOMJMM_01698 2.7e-199 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
HFLOMJMM_01699 1.95e-195 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
HFLOMJMM_01700 1.71e-205 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
HFLOMJMM_01701 7.47e-173 - - - K ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C-terminal domain protein
HFLOMJMM_01702 6.3e-104 - - - L - - - Transposase
HFLOMJMM_01703 2.78e-48 - - - L - - - Transposase
HFLOMJMM_01705 1.66e-247 - - - - - - - -
HFLOMJMM_01706 4.01e-127 - - - K - - - acetyltransferase
HFLOMJMM_01707 1.54e-147 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
HFLOMJMM_01708 1.93e-210 - - - K - - - LysR substrate binding domain
HFLOMJMM_01709 2.09e-268 - 1.1.1.90 - C ko:K00055 ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Zn-dependent alcohol dehydrogenases, class III
HFLOMJMM_01710 3.88e-71 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HFLOMJMM_01711 4.54e-241 - - - - - - - -
HFLOMJMM_01712 4.8e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HFLOMJMM_01713 2.66e-235 - - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
HFLOMJMM_01715 1.27e-99 - - - L - - - PFAM Integrase catalytic region
HFLOMJMM_01717 1.58e-204 metQ1 - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
HFLOMJMM_01718 1.62e-115 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HFLOMJMM_01719 2.31e-163 - - - O - - - Zinc-dependent metalloprotease
HFLOMJMM_01720 2.26e-149 - - - S - - - Membrane
HFLOMJMM_01721 8.69e-257 - 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
HFLOMJMM_01722 7.98e-223 tnp2 - - L - - - PFAM Transposase, IS204 IS1001 IS1096 IS1165
HFLOMJMM_01723 0.0 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
HFLOMJMM_01724 1.3e-304 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HFLOMJMM_01725 9.92e-53 - - - S - - - Cytochrome B5
HFLOMJMM_01726 2.54e-36 - - - - - - - -
HFLOMJMM_01727 3.85e-123 - - - S - - - Domain of unknown function (DUF4767)
HFLOMJMM_01728 5.26e-19 - - - - - - - -
HFLOMJMM_01729 7.09e-273 thiP - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
HFLOMJMM_01730 1.52e-125 - - - K - - - PFAM GCN5-related N-acetyltransferase
HFLOMJMM_01731 9.83e-106 - - - - - - - -
HFLOMJMM_01732 1.71e-173 - - - M - - - Lysin motif
HFLOMJMM_01733 1.97e-257 - - - EGP - - - Major Facilitator
HFLOMJMM_01734 5.37e-112 ywlG - - S - - - Belongs to the UPF0340 family
HFLOMJMM_01735 1.03e-206 - - - J - - - Methyltransferase
HFLOMJMM_01736 5.16e-289 oxlT - - P ko:K08177 - ko00000,ko02000 Major Facilitator Superfamily
HFLOMJMM_01737 1.51e-301 - - - L - - - Belongs to the 'phage' integrase family
HFLOMJMM_01738 7.81e-46 - - - S - - - Domain of unknown function (DUF3173)
HFLOMJMM_01740 0.0 - - - - - - - -
HFLOMJMM_01741 3.94e-221 - - - - - - - -
HFLOMJMM_01742 1.43e-110 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HFLOMJMM_01743 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
HFLOMJMM_01744 0.0 - - - G - - - Major Facilitator Superfamily
HFLOMJMM_01745 1.48e-64 - - - V - - - DNA modification
HFLOMJMM_01746 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
HFLOMJMM_01748 4.23e-289 - - - S ko:K07133 - ko00000 cog cog1373
HFLOMJMM_01749 2.04e-226 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
HFLOMJMM_01750 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HFLOMJMM_01751 6.71e-207 - - - EG - - - EamA-like transporter family
HFLOMJMM_01752 4.64e-37 - - - Q - - - pyridine nucleotide-disulphide oxidoreductase
HFLOMJMM_01753 7.64e-294 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HFLOMJMM_01754 4.91e-80 - - - L ko:K07491 - ko00000 PFAM transposase IS200-family protein
HFLOMJMM_01755 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
HFLOMJMM_01756 8.39e-151 - - - S ko:K03975 - ko00000 SNARE associated Golgi protein
HFLOMJMM_01757 1.64e-162 pgm3 - - G - - - phosphoglycerate mutase
HFLOMJMM_01758 1.58e-301 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HFLOMJMM_01759 1.34e-47 - - - S - - - Transglycosylase associated protein
HFLOMJMM_01760 6.22e-10 - - - S - - - CsbD-like
HFLOMJMM_01761 1.76e-234 - 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HFLOMJMM_01762 0.0 yhgE - - V ko:K01421 - ko00000 domain protein
HFLOMJMM_01763 2.14e-123 - - - K - - - Transcriptional regulator (TetR family)
HFLOMJMM_01764 6.09e-53 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 positive regulation of macromolecule biosynthetic process
HFLOMJMM_01765 3.42e-195 - - - - - - - -
HFLOMJMM_01766 1.37e-40 - 3.2.1.14 GH18 - ko:K01183 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 -
HFLOMJMM_01767 1.27e-108 zur - - P ko:K02076,ko:K03711 - ko00000,ko03000 Belongs to the Fur family
HFLOMJMM_01768 5.82e-136 gmk2 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Guanylate kinase
HFLOMJMM_01769 2.53e-97 - - - F - - - Nudix hydrolase
HFLOMJMM_01770 0.0 yhdG - - E ko:K03294 - ko00000 Amino Acid
HFLOMJMM_01771 5.29e-300 - - - EGP ko:K08368 - ko00000,ko02000 Sugar (and other) transporter
HFLOMJMM_01772 1.06e-297 - - - - - - - -
HFLOMJMM_01773 2.54e-268 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HFLOMJMM_01774 5.39e-184 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HFLOMJMM_01775 2.49e-187 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HFLOMJMM_01776 1.25e-262 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HFLOMJMM_01777 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HFLOMJMM_01778 1.5e-226 pepR 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
HFLOMJMM_01779 0.0 atp2C1 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
HFLOMJMM_01780 2.93e-112 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
HFLOMJMM_01781 0.0 yagE - - E - - - amino acid
HFLOMJMM_01782 4.01e-153 - - - S - - - HAD hydrolase, family IA, variant
HFLOMJMM_01783 1.24e-37 - - - S - - - PD-(D/E)XK nuclease family transposase
HFLOMJMM_01784 3.33e-33 - - - L - - - Helix-turn-helix domain
HFLOMJMM_01785 6.11e-111 - - - L - - - Helix-turn-helix domain
HFLOMJMM_01786 1.91e-164 - - - L ko:K07497 - ko00000 hmm pf00665
HFLOMJMM_01787 1.51e-236 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
HFLOMJMM_01788 1.1e-232 iunH1 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 nucleoside hydrolase
HFLOMJMM_01789 7.72e-178 - - - IQ - - - KR domain
HFLOMJMM_01790 1.26e-172 - - - S ko:K07090 - ko00000 membrane transporter protein
HFLOMJMM_01791 1.55e-129 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
HFLOMJMM_01792 0.0 - - - S ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HFLOMJMM_01793 1.5e-149 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
HFLOMJMM_01794 6.5e-71 - - - - - - - -
HFLOMJMM_01795 0.0 nhaK - - P ko:K03316 - ko00000 Sodium proton antiporter
HFLOMJMM_01796 6.35e-69 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
HFLOMJMM_01797 2.19e-214 ybcH - - D ko:K06889 - ko00000 Alpha beta
HFLOMJMM_01798 1.3e-95 - - - K - - - Transcriptional regulator
HFLOMJMM_01799 1.26e-209 - - - - - - - -
HFLOMJMM_01800 4.33e-234 - - - C - - - Zinc-binding dehydrogenase
HFLOMJMM_01801 0.0 - - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system Galactitol-specific IIC component
HFLOMJMM_01802 1.18e-271 - - - EGP - - - Major Facilitator
HFLOMJMM_01803 4.99e-179 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HFLOMJMM_01804 6.26e-156 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
HFLOMJMM_01805 3.18e-11 - - - - - - - -
HFLOMJMM_01806 4.37e-84 - - - - - - - -
HFLOMJMM_01807 4.97e-249 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
HFLOMJMM_01808 7.46e-106 uspA3 - - T - - - universal stress protein
HFLOMJMM_01809 0.0 fusA1 - - J - - - elongation factor G
HFLOMJMM_01810 3.22e-215 - - - GK - - - ROK family
HFLOMJMM_01811 6.47e-316 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
HFLOMJMM_01812 8.19e-107 - - - L ko:K07491 - ko00000 Transposase IS200 like
HFLOMJMM_01813 1.72e-305 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HFLOMJMM_01814 2.71e-181 yfhR3 - - S ko:K06889 - ko00000 Serine hydrolase (FSH1)
HFLOMJMM_01815 3.68e-311 - - - E - - - amino acid
HFLOMJMM_01816 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
HFLOMJMM_01817 2.22e-173 gntR - - K - - - UbiC transcription regulator-associated domain protein
HFLOMJMM_01818 6.99e-115 ebsC - - J ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HFLOMJMM_01819 0.0 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HFLOMJMM_01820 0.0 yfiC - - V ko:K06147 - ko00000,ko02000 ABC transporter
HFLOMJMM_01821 0.0 ycfI - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
HFLOMJMM_01822 4.05e-242 ldhA 1.1.1.28 - C ko:K03778,ko:K18347 ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01504 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HFLOMJMM_01823 4.13e-116 - - - S ko:K16927 - ko00000,ko00002,ko02000 ECF transporter, substrate-specific component
HFLOMJMM_01824 3.57e-81 - - - S - - - Domain of unknown function (DUF4430)
HFLOMJMM_01825 1.6e-247 cobT 2.4.2.21 - F ko:K00768 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)
HFLOMJMM_01826 2.5e-171 - - - H - - - Uroporphyrinogen-III synthase
HFLOMJMM_01827 3.23e-145 cobC 3.1.3.73 - G ko:K02226 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
HFLOMJMM_01828 1.05e-176 cobS 2.7.8.26 - H ko:K02233 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
HFLOMJMM_01829 1.47e-132 cobU 2.7.1.156, 2.7.7.62 - H ko:K02231 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Cobinamide kinase / cobinamide phosphate guanyltransferase
HFLOMJMM_01830 0.0 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class-III
HFLOMJMM_01831 1.39e-232 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Delta-aminolevulinic acid dehydratase
HFLOMJMM_01832 1.73e-217 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
HFLOMJMM_01833 3.46e-303 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HFLOMJMM_01834 9.88e-105 cysG 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Putative NAD(P)-binding
HFLOMJMM_01835 0.0 cobQ 6.3.5.10 - H ko:K02232 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
HFLOMJMM_01836 1.24e-191 cbiO - - P ko:K02006 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 part of an ABC transporter complex. Responsible for energy coupling to the transport system
HFLOMJMM_01837 1.43e-151 cbiQ - - P ko:K02008 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
HFLOMJMM_01838 2.56e-70 cbiN - - P ko:K02009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
HFLOMJMM_01839 4.44e-171 cbiM - - P ko:K02007 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
HFLOMJMM_01840 2.2e-161 cbiL 2.1.1.130, 2.1.1.151 - H ko:K03394 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Tetrapyrrole (Corrin/Porphyrin) Methylases
HFLOMJMM_01841 1.51e-188 cbiK 4.99.1.3 - H ko:K02190 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Cobalt chelatase (CbiK)
HFLOMJMM_01842 0.0 cobA 2.1.1.107, 4.2.1.75 - H ko:K02303,ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapyrrole (Corrin/Porphyrin) Methylases
HFLOMJMM_01843 9.74e-177 cobK 1.3.1.106, 1.3.1.54 - H ko:K05895 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Precorrin-6x reductase CbiJ/CobK
HFLOMJMM_01844 5.23e-171 cbiH 2.1.1.131 - H ko:K05934 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Tetrapyrrole (Corrin/Porphyrin) Methylases
HFLOMJMM_01845 1.55e-250 cbiG 3.7.1.12 - H ko:K02189 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Cobalamin synthesis G C-terminus
HFLOMJMM_01846 3.02e-176 cbiF 2.1.1.133, 2.1.1.271 - H ko:K05936 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Tetrapyrrole (Corrin/Porphyrin) Methylases
HFLOMJMM_01847 1.28e-127 cbiT 2.1.1.196 - H ko:K02191 ko00860,map00860 ko00000,ko00001,ko01000 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
HFLOMJMM_01848 5.13e-144 cbiE 2.1.1.289 - H ko:K03399 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Tetrapyrrole (Corrin/Porphyrin) Methylases
HFLOMJMM_01849 6.31e-273 cbiD 2.1.1.195 - H ko:K02188 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
HFLOMJMM_01850 6.88e-160 cbiC 5.4.99.60, 5.4.99.61 - H ko:K06042 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Precorrin-8X methylmutase
HFLOMJMM_01851 3.27e-229 cobD 6.3.1.10 - H ko:K02227 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
HFLOMJMM_01852 0.0 cbiA 6.3.5.11, 6.3.5.9 - F ko:K02224 ko00860,ko01100,ko01120,map00860,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source
HFLOMJMM_01853 3.08e-267 cobD 4.1.1.81 - E ko:K04720 ko00860,map00860 ko00000,ko00001,ko01000 Aminotransferase class I and II
HFLOMJMM_01854 6.73e-244 - - - L - - - PFAM Integrase catalytic region
HFLOMJMM_01855 1.37e-133 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Cobalamin adenosyltransferase
HFLOMJMM_01856 7.23e-202 nqo1 - - S ko:K19784 - ko00000 NADPH-dependent FMN reductase
HFLOMJMM_01857 6.23e-102 ykuP - - C ko:K03839 - ko00000 Flavodoxin
HFLOMJMM_01858 2.69e-95 eutP - - E ko:K04029 - ko00000 Ethanolamine utilisation - propanediol utilisation
HFLOMJMM_01859 5.79e-120 - - - P - - - Cadmium resistance transporter
HFLOMJMM_01860 4.9e-158 pgm1 - - G - - - phosphoglycerate mutase
HFLOMJMM_01861 1.7e-192 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Pfam:Y_phosphatase3C
HFLOMJMM_01862 3.32e-74 - - - E ko:K04031 - ko00000 BMC
HFLOMJMM_01863 1.3e-282 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HFLOMJMM_01864 6.52e-270 pduQ - - C ko:K13921 ko00640,map00640 ko00000,ko00001 Iron-containing alcohol dehydrogenase
HFLOMJMM_01865 0.0 pduP 1.2.1.87 - C ko:K13922 ko00640,map00640 ko00000,ko00001,ko01000 Aldehyde dehydrogenase family
HFLOMJMM_01866 1.01e-104 pduO - - S - - - Haem-degrading
HFLOMJMM_01867 1.26e-137 - - - S - - - Cobalamin adenosyltransferase
HFLOMJMM_01868 1.96e-55 pduN - - CQ ko:K04028 - ko00000 Ethanolamine utilisation protein EutN/carboxysome
HFLOMJMM_01869 2.75e-116 - - - S - - - Putative propanediol utilisation
HFLOMJMM_01870 1.77e-151 pduL 2.3.1.222 - Q ko:K13923 ko00640,map00640 ko00000,ko00001,ko01000 Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate
HFLOMJMM_01871 4.11e-57 pduA_2 - - CQ ko:K04027 - ko00000 BMC
HFLOMJMM_01872 1.02e-115 - - - CQ - - - BMC
HFLOMJMM_01873 1.44e-79 pduH - - S - - - Dehydratase medium subunit
HFLOMJMM_01874 0.0 pduG - - D - - - Diol dehydratase reactivase ATPase-like domain
HFLOMJMM_01875 5.05e-112 pduE 4.2.1.28 - Q ko:K13920 ko00640,map00640 ko00000,ko00001,ko01000 Dehydratase small subunit
HFLOMJMM_01876 1.33e-166 pduD 4.2.1.28 - Q ko:K13919 ko00640,map00640 ko00000,ko00001,ko01000 Dehydratase medium subunit
HFLOMJMM_01877 0.0 pduC 4.2.1.28 - Q ko:K01699 ko00640,map00640 ko00000,ko00001,ko01000 Dehydratase large subunit
HFLOMJMM_01878 3.41e-170 pduB - - E - - - BMC
HFLOMJMM_01879 2.72e-56 - - - CQ - - - BMC
HFLOMJMM_01880 1.69e-258 - - - K - - - helix_turn_helix, arabinose operon control protein
HFLOMJMM_01881 3.27e-192 eutJ - - E ko:K04024 - ko00000 Hsp70 protein
HFLOMJMM_01882 4.17e-174 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
HFLOMJMM_01883 5.87e-213 - - - - - - - -
HFLOMJMM_01884 5.33e-208 - - - G - - - Xylose isomerase domain protein TIM barrel
HFLOMJMM_01885 2.08e-245 XK27_12525 - - S - - - AI-2E family transporter
HFLOMJMM_01886 7.74e-173 XK27_07210 - - S - - - B3 4 domain
HFLOMJMM_01887 5.75e-103 yybA - - K - - - Transcriptional regulator
HFLOMJMM_01888 1.51e-117 - - - K - - - Domain of unknown function (DUF1836)
HFLOMJMM_01889 2.93e-119 - - - GM - - - epimerase
HFLOMJMM_01890 1.51e-202 - - - V - - - (ABC) transporter
HFLOMJMM_01891 6.04e-309 yhdP - - S - - - Transporter associated domain
HFLOMJMM_01892 1.98e-110 nrdI - - F ko:K03647 - ko00000 Belongs to the NrdI family
HFLOMJMM_01893 1.82e-97 - - - S ko:K04750 - ko00000 3-demethylubiquinone-9 3-methyltransferase
HFLOMJMM_01894 1.59e-247 yycB - - P ko:K03449 - ko00000,ko02000 Transporter, major facilitator family protein
HFLOMJMM_01895 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HFLOMJMM_01896 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HFLOMJMM_01897 3.16e-55 - - - - - - - -
HFLOMJMM_01898 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
HFLOMJMM_01899 2.32e-104 usp5 - - T - - - universal stress protein
HFLOMJMM_01900 1.39e-106 - - - K ko:K03719 - ko00000,ko03000,ko03036 AsnC family
HFLOMJMM_01901 3.7e-297 gltT - - U ko:K03309,ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HFLOMJMM_01902 9.09e-142 apl 3.1.3.1 - S ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 SNARE associated Golgi protein
HFLOMJMM_01903 8.19e-107 - - - L ko:K07482 - ko00000 transposase and inactivated derivatives, IS30 family
HFLOMJMM_01904 1.31e-140 - - - L - - - Transposase and inactivated derivatives, IS30 family
HFLOMJMM_01905 5.06e-234 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
HFLOMJMM_01906 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
HFLOMJMM_01907 1.08e-289 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HFLOMJMM_01908 7.24e-239 celE3 - - E - - - GDSL-like Lipase/Acylhydrolase family
HFLOMJMM_01909 4.87e-190 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
HFLOMJMM_01910 1.65e-122 - - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
HFLOMJMM_01911 1.21e-48 - - - - - - - -
HFLOMJMM_01912 4.33e-69 - - - - - - - -
HFLOMJMM_01913 2.72e-262 - - - - - - - -
HFLOMJMM_01914 8.19e-108 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HFLOMJMM_01915 5.87e-177 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
HFLOMJMM_01916 2.25e-205 yvgN - - S - - - Aldo keto reductase
HFLOMJMM_01917 6.91e-164 XK27_10500 - - K - - - response regulator
HFLOMJMM_01918 7.79e-236 - - - T - - - Histidine kinase-like ATPases
HFLOMJMM_01919 5.22e-176 XK27_05695 - - V ko:K02003,ko:K19083 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HFLOMJMM_01920 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
HFLOMJMM_01921 1.78e-204 metA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
HFLOMJMM_01922 4.75e-216 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
HFLOMJMM_01923 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HFLOMJMM_01924 7.66e-255 - - - EGP - - - Major Facilitator
HFLOMJMM_01925 8.53e-120 ymdB - - S - - - Macro domain protein
HFLOMJMM_01926 1.03e-146 - - - K - - - Helix-turn-helix XRE-family like proteins
HFLOMJMM_01927 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
HFLOMJMM_01928 1.48e-64 - - - - - - - -
HFLOMJMM_01929 2.59e-314 - - - S - - - Putative metallopeptidase domain
HFLOMJMM_01930 3.49e-269 - - - S - - - associated with various cellular activities
HFLOMJMM_01931 8.15e-155 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
HFLOMJMM_01932 1.92e-86 yeaO - - S - - - Protein of unknown function, DUF488
HFLOMJMM_01934 2.8e-159 yrkL - - S - - - Flavodoxin-like fold
HFLOMJMM_01935 8.14e-73 - - - - - - - -
HFLOMJMM_01937 4.75e-184 - - - S - - - PD-(D/E)XK nuclease family transposase
HFLOMJMM_01938 2.48e-66 - - - - - - - -
HFLOMJMM_01939 5.51e-264 yngD - - S ko:K07097 - ko00000 DHHA1 domain
HFLOMJMM_01940 2.81e-297 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
HFLOMJMM_01941 0.0 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
HFLOMJMM_01942 1.79e-138 - - - NU - - - mannosyl-glycoprotein
HFLOMJMM_01943 1.57e-190 - - - S - - - Putative ABC-transporter type IV
HFLOMJMM_01944 0.0 - - - S - - - ABC transporter, ATP-binding protein
HFLOMJMM_01947 1.15e-139 - - - S - - - Protein of unknown function (DUF3278)
HFLOMJMM_01948 3.01e-19 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
HFLOMJMM_01950 3.5e-186 - - - M - - - PFAM NLP P60 protein
HFLOMJMM_01951 7.76e-234 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
HFLOMJMM_01952 1.18e-196 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HFLOMJMM_01953 3.96e-177 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HFLOMJMM_01954 6.27e-125 - - - P - - - Cadmium resistance transporter
HFLOMJMM_01955 1.14e-74 czrA - - K ko:K22043 - ko00000,ko03000 Transcriptional regulator, ArsR family
HFLOMJMM_01956 6.78e-306 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
HFLOMJMM_01957 6.46e-74 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
HFLOMJMM_01958 3.78e-169 yceF - - P ko:K05794 - ko00000 membrane
HFLOMJMM_01959 9.37e-227 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
HFLOMJMM_01960 8.21e-216 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
HFLOMJMM_01961 0.0 pepD1 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HFLOMJMM_01962 5.83e-308 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
HFLOMJMM_01963 4.33e-315 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
HFLOMJMM_01964 9.6e-317 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
HFLOMJMM_01965 5.94e-128 - - - S - - - Family of unknown function (DUF5449)
HFLOMJMM_01966 2.32e-234 - 4.1.1.22 - H ko:K01590 ko00340,ko01100,ko01110,map00340,map01100,map01110 ko00000,ko00001,ko01000 Histidine carboxylase PI chain
HFLOMJMM_01967 0.0 - - - E ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
HFLOMJMM_01968 0.0 - - - S - - - Uncharacterised protein family (UPF0236)
HFLOMJMM_01969 0.0 - - - S - - - C4-dicarboxylate anaerobic carrier
HFLOMJMM_01970 4.03e-163 pgm3 - - G - - - phosphoglycerate mutase family
HFLOMJMM_01971 1.77e-56 - - - - - - - -
HFLOMJMM_01972 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HFLOMJMM_01973 6.52e-270 gldA 1.1.1.6 - C ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 ko00000,ko00001,ko01000 dehydrogenase
HFLOMJMM_01974 3.54e-181 - - - S - - - Alpha beta hydrolase
HFLOMJMM_01975 6.17e-281 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
HFLOMJMM_01976 3.48e-134 - - - - - - - -
HFLOMJMM_01978 5.09e-162 - - - M - - - ErfK YbiS YcfS YnhG
HFLOMJMM_01979 1.4e-120 - - - S - - - Putative peptidoglycan binding domain
HFLOMJMM_01980 1.25e-54 - - - S - - - Putative peptidoglycan binding domain
HFLOMJMM_01981 1.34e-145 nnrE 5.1.99.6 - H ko:K17759 - ko00000,ko01000 Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
HFLOMJMM_01982 1.8e-115 - - - - - - - -
HFLOMJMM_01983 1.38e-311 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
HFLOMJMM_01984 2.7e-277 yttB - - EGP - - - Major Facilitator
HFLOMJMM_01985 1.52e-148 - - - - - - - -
HFLOMJMM_01986 2.6e-33 - - - - - - - -
HFLOMJMM_01987 1.38e-223 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional regulator, LacI family
HFLOMJMM_01988 0.0 - 3.2.1.17 CBM50 NU ko:K01185,ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HFLOMJMM_01989 2.75e-66 czrA - - K ko:K22043 - ko00000,ko03000 Transcriptional regulator, ArsR family
HFLOMJMM_01990 2.89e-51 - - - - - - - -
HFLOMJMM_01991 0.0 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HFLOMJMM_01992 2.58e-156 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HFLOMJMM_01993 2.5e-236 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
HFLOMJMM_01994 5.75e-117 - - - K - - - transcriptional regulator (TetR family)
HFLOMJMM_01995 9.96e-244 - - - E - - - Zinc-binding dehydrogenase
HFLOMJMM_01996 0.0 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
HFLOMJMM_01997 2.09e-86 - - - - - - - -
HFLOMJMM_01998 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HFLOMJMM_02000 5.75e-117 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 Vacuole effluxer Atg22 like
HFLOMJMM_02001 1.36e-141 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 Vacuole effluxer Atg22 like
HFLOMJMM_02002 0.0 npp - - S - - - type I phosphodiesterase nucleotide pyrophosphatase
HFLOMJMM_02003 4.54e-316 - - - E ko:K03294 - ko00000 amino acid
HFLOMJMM_02004 1.46e-236 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HFLOMJMM_02006 2.33e-39 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
HFLOMJMM_02007 9.7e-06 - - - S - - - Protein of unknown function (DUF3278)
HFLOMJMM_02008 2.61e-283 - 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
HFLOMJMM_02009 5.47e-55 - - - S - - - Cytochrome B5
HFLOMJMM_02010 8.47e-08 - - - S - - - Cytochrome B5
HFLOMJMM_02011 2.3e-52 - - - S - - - Cytochrome B5
HFLOMJMM_02012 7.65e-101 - - - S ko:K02348 - ko00000 Gnat family
HFLOMJMM_02013 6.67e-158 - - - GM - - - NmrA-like family
HFLOMJMM_02014 2.74e-69 ydeP - - K - - - Transcriptional regulator, HxlR family
HFLOMJMM_02015 1.41e-141 XK27_02070 - - S ko:K07078 - ko00000 Nitroreductase family
HFLOMJMM_02016 1.85e-108 - - - K - - - Transcriptional regulator, HxlR family
HFLOMJMM_02017 6.82e-309 - - - - - - - -
HFLOMJMM_02018 2.28e-270 - - - EGP - - - Major Facilitator Superfamily
HFLOMJMM_02019 0.0 pepE 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
HFLOMJMM_02020 6.4e-149 - - - GM - - - NAD dependent epimerase dehydratase family protein
HFLOMJMM_02021 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
HFLOMJMM_02022 1.37e-123 - - - S - - - ECF transporter, substrate-specific component
HFLOMJMM_02023 1.23e-253 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
HFLOMJMM_02024 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
HFLOMJMM_02025 3.29e-162 - - - T - - - Putative diguanylate phosphodiesterase
HFLOMJMM_02026 1.75e-263 - 2.7.7.65 - T ko:K02488 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko00002,ko01000,ko02022 GGDEF domain
HFLOMJMM_02027 7.04e-118 - - - - - - - -
HFLOMJMM_02028 0.0 yijG - GT2 M ko:K11936 ko02026,map02026 ko00000,ko00001,ko01000,ko01003,ko02000 Glycosyl transferase
HFLOMJMM_02029 1.07e-205 - - - T - - - EAL domain
HFLOMJMM_02030 4.71e-112 - - - L ko:K07491 - ko00000 PFAM transposase IS200-family protein
HFLOMJMM_02031 4.18e-168 - - - F - - - glutamine amidotransferase
HFLOMJMM_02032 1.74e-85 - - - - - - - -
HFLOMJMM_02033 1.15e-147 - - - GM - - - NAD(P)H-binding
HFLOMJMM_02034 6.54e-253 - - - S - - - membrane
HFLOMJMM_02035 6.78e-136 - - - K - - - Transcriptional regulator C-terminal region
HFLOMJMM_02036 5.33e-210 akr5f 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
HFLOMJMM_02037 1.64e-203 - - - K - - - Transcriptional regulator
HFLOMJMM_02038 3.43e-236 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase, type I
HFLOMJMM_02039 1.45e-214 ypuA - - S - - - Protein of unknown function (DUF1002)
HFLOMJMM_02040 1.17e-291 aadAT - - EK ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko01000 Aminotransferase, class I
HFLOMJMM_02041 2.28e-223 hdhL 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
HFLOMJMM_02042 1.46e-196 mhpD - - Q ko:K02509 ko00350,ko01120,map00350,map01120 ko00000,ko00001,ko01000 hydratase
HFLOMJMM_02043 2.15e-171 - - - S - - - Alpha beta hydrolase
HFLOMJMM_02044 1.48e-05 - - - S - - - Hydrolases of the alpha beta superfamily
HFLOMJMM_02045 2.21e-115 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
HFLOMJMM_02046 1.35e-206 lysR - - K - - - Transcriptional regulator
HFLOMJMM_02047 5e-116 - - - C - - - Flavodoxin
HFLOMJMM_02048 1.16e-14 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 Oxidoreductase, aldo keto reductase family protein
HFLOMJMM_02049 2e-73 yphJ 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 decarboxylase
HFLOMJMM_02050 6.2e-155 - - - M - - - Protein of unknown function (DUF3737)
HFLOMJMM_02051 1.21e-292 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
HFLOMJMM_02052 3.3e-208 - - - S ko:K07088 - ko00000 Membrane transport protein
HFLOMJMM_02053 1.76e-161 - - - H - - - RibD C-terminal domain
HFLOMJMM_02055 7.86e-243 - - - L - - - PFAM Integrase catalytic region
HFLOMJMM_02056 5.59e-54 - - - H - - - RibD C-terminal domain
HFLOMJMM_02057 1.15e-26 - - - S - - - PemK-like, MazF-like toxin of type II toxin-antitoxin system
HFLOMJMM_02058 3.43e-27 - - - L - - - Addiction module antitoxin, RelB DinJ family
HFLOMJMM_02059 6.53e-118 - - - J ko:K19055 - ko00000,ko01000,ko03016 Aminoacyl-tRNA editing domain
HFLOMJMM_02060 9.8e-75 - - - S - - - Antibiotic biosynthesis monooxygenase
HFLOMJMM_02061 5.85e-254 flp - - V - - - Beta-lactamase
HFLOMJMM_02062 2.6e-124 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
HFLOMJMM_02063 2.81e-158 - - - S ko:K07507 - ko00000,ko02000 MgtC family
HFLOMJMM_02064 4.91e-156 - - - S - - - GyrI-like small molecule binding domain
HFLOMJMM_02066 7.82e-161 - - - S - - - Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
HFLOMJMM_02067 1.58e-66 azlD - - E - - - Branched-chain amino acid transport
HFLOMJMM_02068 5.61e-156 azlC - - E - - - azaleucine resistance protein AzlC
HFLOMJMM_02069 0.0 - - - K - - - Aminotransferase class I and II
HFLOMJMM_02070 0.0 - - - S - - - amidohydrolase
HFLOMJMM_02071 1.86e-212 - - - S - - - reductase
HFLOMJMM_02072 2.55e-120 - 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase, GNAT family
HFLOMJMM_02073 2.44e-147 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HFLOMJMM_02074 1.81e-315 yxbA 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp enzyme
HFLOMJMM_02075 0.0 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HFLOMJMM_02076 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
HFLOMJMM_02077 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HFLOMJMM_02078 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HFLOMJMM_02079 3.01e-177 jag - - S ko:K06346 - ko00000 R3H domain protein
HFLOMJMM_02080 2.96e-172 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HFLOMJMM_02081 2.41e-77 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HFLOMJMM_02082 7.96e-21 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)