ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
MEPAFCOE_00001 1.25e-153 - - - S - - - Protein of unknown function (DUF1461)
MEPAFCOE_00002 7.44e-187 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MEPAFCOE_00003 2.07e-126 yutD - - S - - - Protein of unknown function (DUF1027)
MEPAFCOE_00004 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
MEPAFCOE_00005 2.17e-146 - - - S - - - Calcineurin-like phosphoesterase
MEPAFCOE_00006 3.54e-194 yeaE - - S - - - Aldo keto
MEPAFCOE_00007 0.0 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
MEPAFCOE_00008 2.16e-282 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MEPAFCOE_00009 4.88e-237 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
MEPAFCOE_00010 5.67e-96 - - - - ko:K02248 - ko00000,ko00002,ko02044 -
MEPAFCOE_00012 6.48e-104 - - - - - - - -
MEPAFCOE_00013 1.61e-64 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 competence protein ComGC
MEPAFCOE_00014 3.54e-216 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
MEPAFCOE_00015 3.77e-220 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
MEPAFCOE_00016 1.68e-169 yebC - - K - - - Transcriptional regulatory protein
MEPAFCOE_00017 0.0 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
MEPAFCOE_00018 1.97e-173 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MEPAFCOE_00019 2.37e-168 - - - - - - - -
MEPAFCOE_00020 7.14e-231 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
MEPAFCOE_00021 2.45e-270 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
MEPAFCOE_00022 1.38e-73 - - - - - - - -
MEPAFCOE_00023 3.9e-82 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MEPAFCOE_00024 2.7e-199 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
MEPAFCOE_00025 2.17e-62 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
MEPAFCOE_00027 3.37e-110 ykuL - - S - - - (CBS) domain
MEPAFCOE_00028 1.41e-125 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
MEPAFCOE_00029 5.97e-138 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MEPAFCOE_00030 7.98e-188 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
MEPAFCOE_00031 4.87e-118 yslB - - S - - - Protein of unknown function (DUF2507)
MEPAFCOE_00032 5.12e-71 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
MEPAFCOE_00033 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MEPAFCOE_00034 5.2e-115 cvpA - - S - - - Colicin V production protein
MEPAFCOE_00035 1.62e-53 - - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MEPAFCOE_00036 2.47e-68 yrzB - - S - - - Belongs to the UPF0473 family
MEPAFCOE_00037 7.07e-97 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MEPAFCOE_00038 1.94e-59 yrzL - - S - - - Belongs to the UPF0297 family
MEPAFCOE_00039 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MEPAFCOE_00040 0.0 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MEPAFCOE_00041 5.26e-230 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
MEPAFCOE_00042 3.87e-231 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MEPAFCOE_00043 7.43e-46 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
MEPAFCOE_00044 3.07e-288 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MEPAFCOE_00045 3.96e-254 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MEPAFCOE_00046 9.56e-243 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MEPAFCOE_00047 1.07e-137 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MEPAFCOE_00048 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MEPAFCOE_00049 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MEPAFCOE_00050 8.08e-191 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 YmdB-like protein
MEPAFCOE_00051 6.75e-314 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
MEPAFCOE_00053 3.9e-248 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MEPAFCOE_00054 6.05e-290 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
MEPAFCOE_00055 4.55e-131 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MEPAFCOE_00056 2.57e-141 ymfM - - S ko:K15539 - ko00000 Domain of unknown function (DUF4115)
MEPAFCOE_00057 7.68e-311 ymfH - - S - - - Peptidase M16
MEPAFCOE_00058 9.21e-304 ymfF - - S - - - Peptidase M16 inactive domain protein
MEPAFCOE_00059 1.85e-204 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
MEPAFCOE_00060 8.68e-121 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MEPAFCOE_00061 5.65e-143 - - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter permease
MEPAFCOE_00062 1.57e-190 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
MEPAFCOE_00063 1.18e-149 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
MEPAFCOE_00064 3.16e-119 mreD - - M ko:K03571 - ko00000,ko03036 rod shape-determining protein MreD
MEPAFCOE_00065 5.11e-183 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
MEPAFCOE_00066 1.71e-218 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
MEPAFCOE_00067 3.27e-150 radC - - L ko:K03630 - ko00000 DNA repair protein
MEPAFCOE_00068 4.82e-315 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
MEPAFCOE_00069 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MEPAFCOE_00070 5.75e-119 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MEPAFCOE_00071 1.27e-290 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MEPAFCOE_00072 5.63e-275 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
MEPAFCOE_00073 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MEPAFCOE_00074 7.76e-108 yebR 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
MEPAFCOE_00075 5.1e-140 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MEPAFCOE_00076 6.78e-81 - - - KLT - - - serine threonine protein kinase
MEPAFCOE_00077 6.01e-147 yktB - - S - - - Belongs to the UPF0637 family
MEPAFCOE_00078 1.3e-104 XK27_05190 - - S - - - Protein of unknown function (DUF1694)
MEPAFCOE_00079 4.23e-306 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
MEPAFCOE_00080 3.68e-55 - - - - - - - -
MEPAFCOE_00081 2.12e-107 uspA - - T - - - universal stress protein
MEPAFCOE_00082 5.48e-204 - - - K - - - Helix-turn-helix XRE-family like proteins
MEPAFCOE_00083 1.5e-234 - 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Glycerophosphoryl diester phosphodiesterase family
MEPAFCOE_00084 1.56e-276 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
MEPAFCOE_00085 3.15e-229 - - - S - - - Protein of unknown function (DUF2785)
MEPAFCOE_00086 3.22e-185 - - - O - - - Band 7 protein
MEPAFCOE_00087 2.71e-66 gcsH2 - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 glycine cleavage
MEPAFCOE_00088 9.13e-282 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
MEPAFCOE_00089 5.6e-45 - - - S - - - Protein of unknown function (DUF2969)
MEPAFCOE_00090 1.11e-69 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
MEPAFCOE_00091 4.82e-230 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
MEPAFCOE_00092 5e-310 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MEPAFCOE_00093 1.11e-45 ywzB - - S - - - Protein of unknown function (DUF1146)
MEPAFCOE_00094 4.49e-88 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
MEPAFCOE_00095 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MEPAFCOE_00096 1.52e-208 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MEPAFCOE_00097 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MEPAFCOE_00098 4.44e-117 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MEPAFCOE_00099 3.81e-77 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MEPAFCOE_00100 7.38e-37 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MEPAFCOE_00101 1.55e-162 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
MEPAFCOE_00102 1.06e-145 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MEPAFCOE_00103 4.47e-295 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MEPAFCOE_00104 5.53e-242 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MEPAFCOE_00105 5.43e-194 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MEPAFCOE_00106 2.65e-247 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MEPAFCOE_00107 7.63e-143 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
MEPAFCOE_00108 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Mur ligase, middle domain
MEPAFCOE_00109 1.29e-172 cobQ - - S ko:K07009 - ko00000 glutamine amidotransferase
MEPAFCOE_00110 2.37e-248 ampC - - V - - - Beta-lactamase
MEPAFCOE_00111 0.0 yfiC - - V ko:K06147 - ko00000,ko02000 ABC transporter
MEPAFCOE_00112 0.0 ycfI - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
MEPAFCOE_00113 5.22e-75 - - - - - - - -
MEPAFCOE_00114 5.55e-29 - - - - - - - -
MEPAFCOE_00115 7.11e-187 - - - T - - - diguanylate cyclase
MEPAFCOE_00116 1.06e-155 - - - T - - - Putative diguanylate phosphodiesterase
MEPAFCOE_00117 9.29e-251 ysdE - - P - - - Citrate transporter
MEPAFCOE_00118 1.03e-217 - - - S - - - NAD:arginine ADP-ribosyltransferase
MEPAFCOE_00120 9.4e-45 - - - - - - - -
MEPAFCOE_00121 1.9e-43 - - - S - - - Phage gp6-like head-tail connector protein
MEPAFCOE_00122 1.72e-259 - - - S ko:K06904 - ko00000 Caudovirus prohead serine protease
MEPAFCOE_00123 8.18e-245 - - - S - - - Phage portal protein
MEPAFCOE_00125 0.0 terL - - S - - - overlaps another CDS with the same product name
MEPAFCOE_00126 3.81e-100 - - - L - - - overlaps another CDS with the same product name
MEPAFCOE_00127 5.17e-71 - - - L - - - HNH endonuclease
MEPAFCOE_00131 1.27e-134 - - - S ko:K06919 - ko00000 Phage plasmid primase, P4
MEPAFCOE_00132 2.27e-119 - - - L - - - Bifunctional DNA primase/polymerase, N-terminal
MEPAFCOE_00137 7.19e-11 - - - K - - - Helix-turn-helix XRE-family like proteins
MEPAFCOE_00138 2.32e-260 - - - L - - - Belongs to the 'phage' integrase family
MEPAFCOE_00141 1.87e-126 - - - S - - - Protein of unknown function (DUF1211)
MEPAFCOE_00142 2.2e-105 tspO - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 TspO/MBR family
MEPAFCOE_00143 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
MEPAFCOE_00144 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
MEPAFCOE_00145 8.7e-198 glcU - - U ko:K05340 - ko00000,ko02000 sugar transport
MEPAFCOE_00146 8.88e-268 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 S-adenosylmethionine-dependent methyltransferase
MEPAFCOE_00147 0.0 yclK - - T - - - Histidine kinase
MEPAFCOE_00148 3.84e-188 yclJ - - K ko:K02483 - ko00000,ko02022 response regulator
MEPAFCOE_00150 0.0 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MEPAFCOE_00151 1.02e-46 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MEPAFCOE_00152 8.72e-301 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
MEPAFCOE_00153 0.0 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MEPAFCOE_00154 8.25e-25 dltX - - S - - - D-Ala-teichoic acid biosynthesis protein
MEPAFCOE_00155 2e-248 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MEPAFCOE_00156 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
MEPAFCOE_00157 2.51e-123 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MEPAFCOE_00158 8.18e-243 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MEPAFCOE_00159 3.4e-229 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
MEPAFCOE_00160 7.03e-216 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MEPAFCOE_00161 1.77e-74 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MEPAFCOE_00162 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MEPAFCOE_00163 1.99e-59 ylxQ - - J - - - ribosomal protein
MEPAFCOE_00164 2.64e-63 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
MEPAFCOE_00165 1.92e-251 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
MEPAFCOE_00166 3.03e-106 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
MEPAFCOE_00167 4.41e-52 - - - - - - - -
MEPAFCOE_00168 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MEPAFCOE_00169 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MEPAFCOE_00170 6.6e-294 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
MEPAFCOE_00171 1.31e-175 cdsA 2.7.7.41 - I ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
MEPAFCOE_00172 1.4e-190 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MEPAFCOE_00173 3.42e-97 - - - - - - - -
MEPAFCOE_00174 2.83e-111 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MEPAFCOE_00175 2.12e-165 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
MEPAFCOE_00176 2.79e-197 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MEPAFCOE_00177 5.38e-183 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
MEPAFCOE_00178 1.63e-173 - - - S ko:K07025 - ko00000 Haloacid dehalogenase-like hydrolase
MEPAFCOE_00179 3.05e-236 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MEPAFCOE_00180 1.23e-57 yazA - - L ko:K07461 - ko00000 GIY-YIG catalytic domain protein
MEPAFCOE_00181 2.3e-173 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
MEPAFCOE_00182 5.71e-152 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
MEPAFCOE_00183 0.0 mdlB - - V ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MEPAFCOE_00184 0.0 mdlA - - V ko:K06148,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MEPAFCOE_00185 1.61e-44 XK26_06720 - - S ko:K09976 - ko00000 Uncharacterised protein family (UPF0154)
MEPAFCOE_00186 2.61e-49 ynzC - - S - - - UPF0291 protein
MEPAFCOE_00187 2.41e-142 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MEPAFCOE_00188 1.66e-100 - - - F - - - nucleoside 2-deoxyribosyltransferase
MEPAFCOE_00189 5.07e-108 - - - - - - - -
MEPAFCOE_00190 1.18e-271 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
MEPAFCOE_00191 3.89e-208 - - - S - - - Polyphosphate nucleotide phosphotransferase, PPK2 family
MEPAFCOE_00192 1.91e-158 pgm3 - - G - - - phosphoglycerate mutase
MEPAFCOE_00193 2.94e-34 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
MEPAFCOE_00194 2.06e-107 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Belongs to the NDK family
MEPAFCOE_00198 3.36e-91 - - - S - - - TIR domain
MEPAFCOE_00199 2.96e-209 - - - I - - - Diacylglycerol kinase catalytic domain
MEPAFCOE_00200 5.89e-98 - - - - - - - -
MEPAFCOE_00201 6.11e-11 - - - K - - - CsbD-like
MEPAFCOE_00202 7.24e-102 - - - T - - - Universal stress protein family
MEPAFCOE_00203 1.03e-118 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MEPAFCOE_00204 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
MEPAFCOE_00205 3.64e-71 yrvD - - S - - - Pfam:DUF1049
MEPAFCOE_00206 6.88e-230 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MEPAFCOE_00207 1.59e-36 - - - - - - - -
MEPAFCOE_00208 1.45e-157 - - - - - - - -
MEPAFCOE_00209 1.28e-54 - - - - - - - -
MEPAFCOE_00211 2.82e-281 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
MEPAFCOE_00213 1.72e-28 - - - E - - - Protein of unknown function (DUF3923)
MEPAFCOE_00214 7.13e-17 - - - S - - - Protein of unknown function (DUF3278)
MEPAFCOE_00215 9.56e-89 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
MEPAFCOE_00216 1.05e-97 - - - L - - - Transposase DDE domain
MEPAFCOE_00217 1.87e-128 - - - L - - - Integrase
MEPAFCOE_00218 4.65e-47 - - - Q - - - ubiE/COQ5 methyltransferase family
MEPAFCOE_00219 3.57e-213 yhgE - - V ko:K01421 - ko00000 domain protein
MEPAFCOE_00220 3.43e-120 epsB - - M - - - biosynthesis protein
MEPAFCOE_00221 2.26e-168 ywqD - - D - - - Capsular exopolysaccharide family
MEPAFCOE_00222 7.89e-177 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
MEPAFCOE_00223 1e-109 rfbP - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 Bacterial sugar transferase
MEPAFCOE_00224 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MEPAFCOE_00225 3.39e-274 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MEPAFCOE_00226 9.61e-155 - - - - - - - -
MEPAFCOE_00227 2.78e-82 - - - - - - - -
MEPAFCOE_00228 8.38e-90 - - - - - - - -
MEPAFCOE_00229 0.0 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Belongs to the DNA polymerase type-Y family
MEPAFCOE_00230 1.11e-70 - - - - - - - -
MEPAFCOE_00231 5.24e-84 - - - - - - - -
MEPAFCOE_00232 4.8e-96 - 1.1.1.29 - CH ko:K00018 ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MEPAFCOE_00233 1.53e-113 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
MEPAFCOE_00234 1.01e-119 - - - O - - - Zinc-dependent metalloprotease
MEPAFCOE_00246 6.78e-102 - - - - - - - -
MEPAFCOE_00247 2.99e-289 - - - EK - - - Aminotransferase, class I
MEPAFCOE_00248 2.44e-211 - - - K - - - LysR substrate binding domain
MEPAFCOE_00250 9.83e-37 - - - - - - - -
MEPAFCOE_00251 2.2e-128 - - - K - - - DNA-templated transcription, initiation
MEPAFCOE_00252 3.57e-260 - - - - - - - -
MEPAFCOE_00253 4.86e-84 - - - - - - - -
MEPAFCOE_00254 7.09e-72 - - - - - - - -
MEPAFCOE_00255 2.19e-249 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Belongs to the DNA polymerase type-Y family
MEPAFCOE_00256 2.56e-289 - - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MEPAFCOE_00257 1.92e-24 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MEPAFCOE_00258 7.05e-139 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
MEPAFCOE_00259 6.85e-189 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
MEPAFCOE_00260 1.48e-176 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MEPAFCOE_00261 1.01e-191 yneD - - S - - - Enoyl-(Acyl carrier protein) reductase
MEPAFCOE_00262 2.26e-166 yjkA - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
MEPAFCOE_00263 8.74e-153 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MEPAFCOE_00264 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MEPAFCOE_00265 2.14e-96 - - - - - - - -
MEPAFCOE_00266 1.48e-114 rmeB - - K - - - transcriptional regulator, MerR family
MEPAFCOE_00267 2.01e-123 - - - J - - - glyoxalase III activity
MEPAFCOE_00268 2.4e-177 XK27_00890 - - S ko:K08974 - ko00000 Domain of unknown function (DUF368)
MEPAFCOE_00269 2.59e-171 - - - K - - - helix_turn_helix, mercury resistance
MEPAFCOE_00270 8.48e-285 xylR - - GK - - - ROK family
MEPAFCOE_00271 4.04e-204 - - - C - - - Aldo keto reductase
MEPAFCOE_00272 5.68e-316 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
MEPAFCOE_00273 0.0 cpdB - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
MEPAFCOE_00274 3.15e-163 - - - S - - - Protein of unknown function (DUF1275)
MEPAFCOE_00275 7.12e-226 ybcH - - D ko:K06889 - ko00000 Alpha beta
MEPAFCOE_00276 0.0 pepF2 - - E - - - Oligopeptidase F
MEPAFCOE_00277 9.09e-97 - - - K - - - Transcriptional regulator
MEPAFCOE_00278 1.86e-210 - - - - - - - -
MEPAFCOE_00279 7.9e-247 - - - S - - - DUF218 domain
MEPAFCOE_00280 8.73e-201 nanK - - GK - - - ROK family
MEPAFCOE_00281 0.0 - - - E - - - Amino acid permease
MEPAFCOE_00282 0.0 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
MEPAFCOE_00283 4.26e-23 - - - S - - - SEC-C Motif Domain Protein
MEPAFCOE_00284 5.45e-268 - - - S ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
MEPAFCOE_00286 9.83e-66 - - - - - - - -
MEPAFCOE_00287 1.11e-100 - - - K ko:K06075 - ko00000,ko03000 Winged helix DNA-binding domain
MEPAFCOE_00288 1.09e-141 nnrE 5.1.99.6 - H ko:K17759 - ko00000,ko01000 Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
MEPAFCOE_00289 2.88e-130 aad 3.4.13.22 - E ko:K08641 ko01502,ko02020,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
MEPAFCOE_00290 6.4e-142 - - - - - - - -
MEPAFCOE_00291 3.06e-238 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MEPAFCOE_00292 1.34e-109 lytE - - M - - - NlpC P60 family
MEPAFCOE_00293 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
MEPAFCOE_00294 0.0 - - - S - - - Predicted membrane protein (DUF2207)
MEPAFCOE_00295 5.22e-270 - - - KLT - - - Protein kinase domain
MEPAFCOE_00296 3.3e-131 - - - S - - - Plasmid replication protein
MEPAFCOE_00297 1.35e-135 mob - - D - - - Plasmid recombination enzyme
MEPAFCOE_00298 2.37e-62 - - - - - - - -
MEPAFCOE_00299 2.41e-30 - - - S - - - Family of unknown function (DUF5388)
MEPAFCOE_00300 3e-152 soj - - D - - - CobQ CobB MinD ParA nucleotide binding domain protein
MEPAFCOE_00301 2.3e-259 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
MEPAFCOE_00302 5.32e-129 - - - L - - - Resolvase, N terminal domain
MEPAFCOE_00303 2.14e-174 - - - I - - - alpha/beta hydrolase fold
MEPAFCOE_00304 7.42e-228 draG - - O - - - ADP-ribosylglycohydrolase
MEPAFCOE_00305 6.17e-133 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
MEPAFCOE_00306 0.0 eriC - - P ko:K03281 - ko00000 chloride
MEPAFCOE_00307 5.04e-75 - - - - - - - -
MEPAFCOE_00309 5.29e-86 - - - L - - - the current gene model (or a revised gene model) may contain a frame shift
MEPAFCOE_00310 1.57e-246 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MEPAFCOE_00311 2.22e-15 - - - C - - - Flavodoxin
MEPAFCOE_00312 1.2e-106 - - - - - - - -
MEPAFCOE_00313 4.61e-272 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
MEPAFCOE_00314 2.82e-194 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
MEPAFCOE_00315 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
MEPAFCOE_00316 2.51e-237 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MEPAFCOE_00317 4.33e-260 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
MEPAFCOE_00318 3.64e-224 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
MEPAFCOE_00319 1.6e-218 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 mevalonate kinase
MEPAFCOE_00320 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
MEPAFCOE_00321 1.08e-113 ypmB - - S - - - Protein conserved in bacteria
MEPAFCOE_00322 5.14e-268 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
MEPAFCOE_00323 1.33e-159 dnaD - - L ko:K02086 - ko00000 Replication initiation and membrane attachment
MEPAFCOE_00324 2.51e-115 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
MEPAFCOE_00325 7.67e-80 - - - P - - - Rhodanese Homology Domain
MEPAFCOE_00326 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
MEPAFCOE_00327 5.76e-146 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MEPAFCOE_00328 1.96e-138 ypsA - - S - - - Belongs to the UPF0398 family
MEPAFCOE_00329 7e-52 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MEPAFCOE_00331 1.98e-279 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
MEPAFCOE_00332 6.93e-88 - - - FG ko:K02503 - ko00000,ko04147 Scavenger mRNA decapping enzyme C-term binding
MEPAFCOE_00333 1.06e-311 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
MEPAFCOE_00334 1.17e-38 - - - - - - - -
MEPAFCOE_00335 5.74e-107 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
MEPAFCOE_00336 1.16e-72 - - - - - - - -
MEPAFCOE_00337 4.85e-158 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
MEPAFCOE_00338 1.5e-112 - - - K - - - Bacterial regulatory proteins, tetR family
MEPAFCOE_00339 1.79e-144 XK27_02070 - - S ko:K07078 - ko00000 Nitroreductase family
MEPAFCOE_00340 9.19e-266 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 FAD dependent oxidoreductase
MEPAFCOE_00341 1.59e-90 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease HI
MEPAFCOE_00342 1.53e-74 esbA - - S - - - Family of unknown function (DUF5322)
MEPAFCOE_00343 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
MEPAFCOE_00344 9.45e-104 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MEPAFCOE_00345 1.8e-220 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
MEPAFCOE_00346 6.85e-115 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MEPAFCOE_00347 3.3e-260 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarA family
MEPAFCOE_00348 0.0 pyrAB2 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
MEPAFCOE_00349 0.0 FbpA - - K - - - Fibronectin-binding protein
MEPAFCOE_00350 2.12e-92 - - - K - - - Transcriptional regulator
MEPAFCOE_00351 2.57e-251 npp - - S - - - type I phosphodiesterase nucleotide pyrophosphatase
MEPAFCOE_00352 3.15e-296 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 Vacuole effluxer Atg22 like
MEPAFCOE_00353 2.42e-204 - - - S - - - EDD domain protein, DegV family
MEPAFCOE_00354 2.29e-113 - - - S - - - ECF transporter, substrate-specific component
MEPAFCOE_00355 2.37e-95 gtcA - - S - - - Teichoic acid glycosylation protein
MEPAFCOE_00356 6.2e-114 ysaA - - V - - - VanZ like family
MEPAFCOE_00357 4.56e-120 - - - V - - - VanZ like family
MEPAFCOE_00358 2.15e-153 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MEPAFCOE_00359 5.66e-188 - - - K - - - helix_turn_helix, mercury resistance
MEPAFCOE_00360 3.15e-229 - - - C - - - Zinc-binding dehydrogenase
MEPAFCOE_00361 4.7e-133 - - - - - - - -
MEPAFCOE_00362 3.98e-126 - - - S - - - Plasmid replication protein
MEPAFCOE_00364 3.69e-189 soj - - D - - - CobQ CobB MinD ParA nucleotide binding domain protein
MEPAFCOE_00365 8.55e-78 - - - S - - - Family of unknown function (DUF5388)
MEPAFCOE_00366 3.75e-54 - - - S - - - Pfam Methyltransferase
MEPAFCOE_00367 7.39e-98 - - - K ko:K03827 - ko00000,ko01000 Acetyltransferase (GNAT) domain
MEPAFCOE_00368 2.16e-122 cadD - - P - - - Cadmium resistance transporter
MEPAFCOE_00370 6.05e-225 - - - EG - - - EamA-like transporter family
MEPAFCOE_00371 4.37e-43 - - - - - - - -
MEPAFCOE_00372 8.83e-06 - - - - - - - -
MEPAFCOE_00373 5.47e-85 - - - D - - - AAA domain
MEPAFCOE_00374 3.7e-94 - - - EGP - - - Major Facilitator
MEPAFCOE_00375 8.44e-201 dkgB - - S - - - reductase
MEPAFCOE_00376 3.58e-283 B4168_4126 - - L ko:K07493 - ko00000 Transposase
MEPAFCOE_00377 0.0 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MEPAFCOE_00378 3.25e-154 csrR - - K - - - response regulator
MEPAFCOE_00379 4.42e-248 adhP 1.1.1.1 - C ko:K00001,ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
MEPAFCOE_00380 8.69e-149 - - - O - - - Zinc-dependent metalloprotease
MEPAFCOE_00381 4.58e-69 czrA - - K ko:K22043 - ko00000,ko03000 Transcriptional regulator, ArsR family
MEPAFCOE_00382 7.47e-190 - 3.1.3.23 - S ko:K07757 - ko00000,ko01000 Sucrose-6F-phosphate phosphohydrolase
MEPAFCOE_00383 4.39e-39 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
MEPAFCOE_00384 6.8e-123 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
MEPAFCOE_00385 8.65e-275 ylbM - - S - - - Belongs to the UPF0348 family
MEPAFCOE_00386 2.93e-180 yqeM - - Q - - - Methyltransferase
MEPAFCOE_00387 1.28e-77 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MEPAFCOE_00388 6.24e-139 yqeK - - H - - - Hydrolase, HD family
MEPAFCOE_00389 1.58e-152 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MEPAFCOE_00390 1.5e-64 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein
MEPAFCOE_00391 9.12e-285 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
MEPAFCOE_00392 2.6e-134 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
MEPAFCOE_00393 6.09e-72 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MEPAFCOE_00394 5.7e-36 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
MEPAFCOE_00395 2.31e-101 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MEPAFCOE_00396 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MEPAFCOE_00397 3.88e-211 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
MEPAFCOE_00398 1.34e-311 dnaB - - L ko:K03346 - ko00000,ko03032 replication initiation and membrane attachment
MEPAFCOE_00399 4.94e-114 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MEPAFCOE_00400 4.86e-142 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MEPAFCOE_00401 1.59e-208 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MEPAFCOE_00402 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MEPAFCOE_00403 0.0 guaD 3.5.4.3 - F ko:K01487 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Amidohydrolase family
MEPAFCOE_00404 1.7e-299 - - - F ko:K03458 - ko00000 Permease
MEPAFCOE_00405 4.23e-153 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
MEPAFCOE_00406 2.69e-169 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
MEPAFCOE_00407 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
MEPAFCOE_00408 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
MEPAFCOE_00409 9.43e-146 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MEPAFCOE_00410 2.29e-74 ytpP - - CO - - - Thioredoxin
MEPAFCOE_00411 2.71e-72 - - - S - - - Small secreted protein
MEPAFCOE_00412 1.97e-311 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
MEPAFCOE_00413 2.14e-188 ald 1.4.1.1 - C ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
MEPAFCOE_00414 9.26e-52 ald 1.4.1.1 - C ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
MEPAFCOE_00415 3.73e-110 - - - T - - - Belongs to the universal stress protein A family
MEPAFCOE_00416 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
MEPAFCOE_00417 2.12e-188 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MEPAFCOE_00418 2.8e-160 - 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 pseudouridine synthase activity
MEPAFCOE_00419 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
MEPAFCOE_00420 1.03e-66 - - - - - - - -
MEPAFCOE_00421 8.42e-188 - - - S - - - NADPH-dependent FMN reductase
MEPAFCOE_00422 1.24e-156 - - - P ko:K01990 - ko00000,ko00002,ko02000 ABC-type multidrug transport system ATPase component
MEPAFCOE_00423 6.49e-70 - - - - - - - -
MEPAFCOE_00424 1.02e-54 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MEPAFCOE_00425 1.98e-214 ytbD - - EGP ko:K19577 - ko00000,ko02000 Major Facilitator
MEPAFCOE_00426 1.7e-149 - - - L - - - Transposase and inactivated derivatives, IS30 family
MEPAFCOE_00427 8.67e-164 - - - L - - - Transposase and inactivated derivatives, IS30 family
MEPAFCOE_00428 4.33e-97 pinR1 - - L - - - Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
MEPAFCOE_00429 1.87e-246 - - - L - - - Transposase and inactivated derivatives, IS30 family
MEPAFCOE_00431 1.96e-224 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
MEPAFCOE_00442 2.94e-49 inlJ - - M - - - MucBP domain
MEPAFCOE_00443 0.0 - - - - - - - -
MEPAFCOE_00444 1.18e-50 - - - - - - - -
MEPAFCOE_00445 0.0 - - - E - - - Peptidase family C69
MEPAFCOE_00446 4.42e-154 rcfA - - K ko:K21562 - ko00000,ko03000 Transcriptional regulator, Crp Fnr family
MEPAFCOE_00447 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
MEPAFCOE_00448 0.0 yxbA 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp enzyme
MEPAFCOE_00449 2.13e-168 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
MEPAFCOE_00450 1e-42 - 2.7.1.194 - G ko:K02821 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MEPAFCOE_00451 9.95e-32 ulaB 2.7.1.194 - G ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase system galactitol-specific IIB component
MEPAFCOE_00452 3.37e-240 ulaA - - S ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
MEPAFCOE_00453 6.51e-314 tkt 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MEPAFCOE_00454 4.43e-275 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MEPAFCOE_00455 9.43e-109 - - - G ko:K03483 - ko00000,ko03000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MEPAFCOE_00456 6.5e-71 - - - S - - - Protein of unknown function (DUF1516)
MEPAFCOE_00457 2.14e-127 ywjB - - H - - - RibD C-terminal domain
MEPAFCOE_00458 1.53e-305 - 3.2.1.96, 3.5.1.28 GH73 M ko:K01227,ko:K01447,ko:K13714,ko:K13731 ko00511,ko05100,map00511,map05100 ko00000,ko00001,ko01000 N-acetylmuramoyl-L-alanine amidase
MEPAFCOE_00459 3.49e-24 - - - - - - - -
MEPAFCOE_00461 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
MEPAFCOE_00462 5.9e-103 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
MEPAFCOE_00463 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
MEPAFCOE_00464 2.44e-71 yheA - - S - - - Belongs to the UPF0342 family
MEPAFCOE_00465 2.3e-297 yhaO - - L ko:K03547 - ko00000,ko03400 Ser Thr phosphatase family protein
MEPAFCOE_00466 0.0 yhaN - - L - - - AAA domain
MEPAFCOE_00467 6.67e-236 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 Metal dependent phosphohydrolases with conserved 'HD' motif.
MEPAFCOE_00468 8.85e-195 prsA 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MEPAFCOE_00469 1.78e-67 - - - - - - - -
MEPAFCOE_00470 5.29e-109 hit - - FG ko:K02503 - ko00000,ko04147 histidine triad
MEPAFCOE_00471 2.85e-173 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MEPAFCOE_00472 5.74e-284 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
MEPAFCOE_00473 1.57e-192 ytmP - - M - - - Choline/ethanolamine kinase
MEPAFCOE_00474 7.82e-160 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MEPAFCOE_00475 6.04e-250 coiA - - S ko:K06198 - ko00000 Competence protein
MEPAFCOE_00476 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
MEPAFCOE_00477 2.15e-202 degV1 - - S - - - DegV family
MEPAFCOE_00478 9.83e-148 yjbH - - Q - - - Thioredoxin
MEPAFCOE_00479 9.43e-154 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
MEPAFCOE_00480 3.71e-193 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MEPAFCOE_00481 3.94e-220 yjbO 5.4.99.23 - G ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
MEPAFCOE_00482 4.68e-67 - - - S ko:K19157 - ko00000,ko01000,ko02048 Bacterial toxin of type II toxin-antitoxin system, YafQ
MEPAFCOE_00483 8.83e-57 - - - S ko:K07473 - ko00000,ko02048 RelB antitoxin
MEPAFCOE_00484 8.93e-113 - - - S - - - Cysteine-rich secretory protein family
MEPAFCOE_00485 9.56e-89 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
MEPAFCOE_00486 3.98e-115 traI 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 This gene contains a nucleotide ambiguity which may be the result of a sequencing error
MEPAFCOE_00487 2.99e-116 - - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
MEPAFCOE_00488 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
MEPAFCOE_00489 8.34e-195 gntR - - K - - - rpiR family
MEPAFCOE_00490 5.71e-190 lys - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
MEPAFCOE_00491 2.89e-84 - - - S - - - Domain of unknown function (DUF4828)
MEPAFCOE_00492 9.54e-241 mocA - - S - - - Oxidoreductase
MEPAFCOE_00493 2.15e-298 yfmL - - L - - - DEAD DEAH box helicase
MEPAFCOE_00496 7.84e-101 - - - T - - - Universal stress protein family
MEPAFCOE_00497 2.22e-296 gntP - - EG ko:K03299 - ko00000,ko02000 Gluconate
MEPAFCOE_00498 6.25e-202 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 Glycosyltransferase like family 2
MEPAFCOE_00499 1.05e-272 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MEPAFCOE_00500 1.3e-201 - - - S - - - Nuclease-related domain
MEPAFCOE_00501 4.48e-203 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
MEPAFCOE_00502 2.17e-102 ykuP - - C ko:K03839 - ko00000 Flavodoxin
MEPAFCOE_00503 8.69e-187 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
MEPAFCOE_00504 1.11e-282 pbpX2 - - V - - - Beta-lactamase
MEPAFCOE_00505 2.15e-52 - - - S - - - Bacteriocin-protection, YdeI or OmpD-Associated
MEPAFCOE_00506 1.5e-140 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
MEPAFCOE_00507 6.54e-253 yueF - - S - - - AI-2E family transporter
MEPAFCOE_00508 2.51e-98 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Glycerol-3-phosphate cytidylyltransferase
MEPAFCOE_00509 1.06e-201 - - - - - - - -
MEPAFCOE_00510 0.0 tagF 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycerophosphotransferase
MEPAFCOE_00511 7.34e-117 - - - - - - - -
MEPAFCOE_00512 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MEPAFCOE_00513 0.0 - - - S - - - Leucine-rich repeat (LRR) protein
MEPAFCOE_00514 0.0 nox 1.6.3.4 - C ko:K17869 - ko00000,ko01000 NADH oxidase
MEPAFCOE_00515 0.0 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
MEPAFCOE_00516 0.0 pacL3 3.6.3.8 - P ko:K01537 - ko00000,ko01000 Cation transporter/ATPase, N-terminus
MEPAFCOE_00517 1.12e-272 - - - G - - - MucBP domain
MEPAFCOE_00518 0.0 clpE - - O ko:K03697 - ko00000,ko03110 Belongs to the ClpA ClpB family
MEPAFCOE_00519 3.61e-42 - - - - - - - -
MEPAFCOE_00520 2.6e-54 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
MEPAFCOE_00521 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MEPAFCOE_00522 2e-285 pimB 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
MEPAFCOE_00523 9.58e-244 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
MEPAFCOE_00524 1.83e-234 mprF - - S ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MEPAFCOE_00525 3.96e-49 ykuJ - - S - - - Protein of unknown function (DUF1797)
MEPAFCOE_00526 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MEPAFCOE_00533 2.63e-58 - - - L - - - DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MEPAFCOE_00534 2.2e-202 - - - S - - - Helix-turn-helix domain
MEPAFCOE_00535 1.66e-105 - - - - - - - -
MEPAFCOE_00537 4.63e-85 - - - S - - - sequence-specific DNA binding
MEPAFCOE_00539 8.97e-129 - - - S - - - DNA binding
MEPAFCOE_00541 7.2e-21 - - - - - - - -
MEPAFCOE_00551 3.44e-11 - - - S - - - Siphovirus Gp157
MEPAFCOE_00552 7.4e-38 - - - S - - - ERF superfamily
MEPAFCOE_00553 1.17e-73 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MEPAFCOE_00554 3.86e-110 - - - S - - - Putative HNHc nuclease
MEPAFCOE_00555 1.62e-113 - - - L - - - DnaD domain protein
MEPAFCOE_00556 2.73e-63 - - - L ko:K02315 - ko00000,ko03032 IstB-like ATP binding protein
MEPAFCOE_00559 0.000322 - - - S - - - C-5 cytosine-specific DNA methylase
MEPAFCOE_00560 1.98e-55 - - - S - - - sequence-specific DNA binding
MEPAFCOE_00563 5.88e-29 - - - S - - - YopX protein
MEPAFCOE_00567 6.39e-62 - - - S - - - Transcriptional regulator, RinA family
MEPAFCOE_00569 1.35e-91 - - - L ko:K07474 - ko00000 Terminase small subunit
MEPAFCOE_00570 4.99e-200 - - - S - - - Terminase-like family
MEPAFCOE_00572 0.0 - - - S - - - Phage portal protein, SPP1 Gp6-like
MEPAFCOE_00573 1.34e-97 - - - S - - - Phage Mu protein F like protein
MEPAFCOE_00574 5.27e-70 - - - S - - - Domain of unknown function (DUF4355)
MEPAFCOE_00575 1.12e-230 gpG - - - - - - -
MEPAFCOE_00577 7.47e-75 - - - - - - - -
MEPAFCOE_00583 2.03e-147 - - - L - - - Probable transposase
MEPAFCOE_00586 0.0 - - - M - - - tape measure
MEPAFCOE_00587 3.36e-76 - - - M - - - LysM domain
MEPAFCOE_00589 6.8e-167 - - - - - - - -
MEPAFCOE_00590 3.99e-55 - - - - - - - -
MEPAFCOE_00592 1.71e-227 - - - S - - - Baseplate J-like protein
MEPAFCOE_00594 5.98e-63 - - - D - - - nuclear chromosome segregation
MEPAFCOE_00596 2.55e-49 - - - - - - - -
MEPAFCOE_00597 9.93e-113 - - - M - - - hydrolase, family 25
MEPAFCOE_00600 7.22e-129 soj - - D - - - CobQ CobB MinD ParA nucleotide binding domain protein
MEPAFCOE_00601 2.53e-173 cat 2.3.1.28 - V ko:K19271 - br01600,ko00000,ko01000,ko01504 Chloramphenicol acetyltransferase
MEPAFCOE_00602 3.71e-281 - 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
MEPAFCOE_00603 2.96e-216 - 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
MEPAFCOE_00604 1.8e-124 - - - S ko:K16925 - ko00000,ko00002,ko02000 ABC transporter permease
MEPAFCOE_00605 0.0 - - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
MEPAFCOE_00606 5.03e-148 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
MEPAFCOE_00607 1.7e-155 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MEPAFCOE_00608 4.78e-79 - - - - - - - -
MEPAFCOE_00609 1.59e-10 - - - - - - - -
MEPAFCOE_00611 3.18e-58 - - - - - - - -
MEPAFCOE_00612 2.69e-276 - - - - - - - -
MEPAFCOE_00613 1.07e-238 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 Asparaginase
MEPAFCOE_00614 9.57e-36 - - - - - - - -
MEPAFCOE_00615 1.82e-316 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
MEPAFCOE_00616 1.8e-215 natA - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MEPAFCOE_00617 3.11e-271 natB - - CP ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
MEPAFCOE_00619 0.0 - - - S - - - Putative threonine/serine exporter
MEPAFCOE_00620 7.25e-206 yitS - - S - - - Uncharacterised protein, DegV family COG1307
MEPAFCOE_00621 1.25e-196 - - - C - - - Aldo keto reductase
MEPAFCOE_00622 4.07e-85 - - - S - - - Protein of unknown function (DUF1722)
MEPAFCOE_00623 5.58e-91 yqeB - - S - - - Pyrimidine dimer DNA glycosylase
MEPAFCOE_00624 0.0 gadB 4.1.1.15, 4.1.2.27 - E ko:K01580,ko:K01634 ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940 ko00000,ko00001,ko00002,ko01000 Belongs to the group II decarboxylase family
MEPAFCOE_00625 4.67e-163 rcfB - - K - - - Crp-like helix-turn-helix domain
MEPAFCOE_00626 1.71e-301 larA 5.1.2.1 - S ko:K22373 ko00620,map00620 ko00000,ko00001,ko01000 Domain of unknown function (DUF2088)
MEPAFCOE_00627 1.13e-171 larB - - S ko:K06898 - ko00000 AIR carboxylase
MEPAFCOE_00628 2.55e-288 larC 4.99.1.12 - S ko:K09121 - ko00000,ko01000 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
MEPAFCOE_00629 2.05e-191 larE - - S ko:K06864 - ko00000 NAD synthase
MEPAFCOE_00630 2.21e-160 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
MEPAFCOE_00631 8.66e-229 - - - U ko:K07241 - ko00000,ko02000 High-affinity nickel-transport protein
MEPAFCOE_00632 2.9e-53 yfhR3 - - S ko:K06889 - ko00000 Serine hydrolase (FSH1)
MEPAFCOE_00633 1.95e-41 yfhR3 - - S ko:K06889 - ko00000 Serine hydrolase (FSH1)
MEPAFCOE_00634 8.39e-54 - - - K - - - Acetyltransferase (GNAT) domain
MEPAFCOE_00635 4.06e-267 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MEPAFCOE_00636 8.33e-189 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MEPAFCOE_00637 1.21e-173 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MEPAFCOE_00638 1.15e-259 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MEPAFCOE_00639 8.38e-190 pstB2 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MEPAFCOE_00640 4.95e-192 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
MEPAFCOE_00641 4.2e-215 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
MEPAFCOE_00642 1.19e-199 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
MEPAFCOE_00643 2.15e-75 - - - - - - - -
MEPAFCOE_00644 1.91e-42 - - - - - - - -
MEPAFCOE_00645 2.14e-57 - - - - - - - -
MEPAFCOE_00646 0.0 uvrB3 3.1.12.1 - KL ko:K07464 - ko00000,ko01000,ko02048 DEAD_2
MEPAFCOE_00647 6.36e-162 - - - - - - - -
MEPAFCOE_00648 2.22e-229 - - - - - - - -
MEPAFCOE_00649 2.7e-60 - - - V - - - ABC transporter transmembrane region
MEPAFCOE_00650 1.32e-119 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
MEPAFCOE_00651 0.0 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Peptidase dimerisation domain
MEPAFCOE_00652 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MEPAFCOE_00653 4.24e-114 - - - - - - - -
MEPAFCOE_00654 1.72e-73 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
MEPAFCOE_00656 2.26e-33 - - - - - - - -
MEPAFCOE_00657 1.08e-102 - - - O - - - OsmC-like protein
MEPAFCOE_00658 2.39e-34 - - - - - - - -
MEPAFCOE_00659 8.55e-99 - - - K - - - Transcriptional regulator
MEPAFCOE_00660 3.69e-114 - - - S - - - Domain of unknown function (DUF5067)
MEPAFCOE_00661 4.33e-195 - - - M ko:K07271 - ko00000,ko01000 LicD family
MEPAFCOE_00662 0.0 ppx3 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
MEPAFCOE_00663 0.0 ppk 2.7.4.1 - P ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MEPAFCOE_00664 1.94e-217 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
MEPAFCOE_00665 3.16e-182 fepC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MEPAFCOE_00666 8.57e-222 isdF - - U ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MEPAFCOE_00667 1.12e-209 isdE - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
MEPAFCOE_00668 9.62e-154 - - - M ko:K14193 ko05150,map05150 ko00000,ko00001 Iron Transport-associated domain
MEPAFCOE_00669 4.98e-256 - - - M - - - Iron Transport-associated domain
MEPAFCOE_00670 5.16e-125 - - - S - - - Iron Transport-associated domain
MEPAFCOE_00671 3.14e-66 - - - - - - - -
MEPAFCOE_00672 2.31e-257 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
MEPAFCOE_00673 6.01e-45 copZ - - P - - - Heavy-metal-associated domain
MEPAFCOE_00674 1.05e-121 dpsB - - P - - - Belongs to the Dps family
MEPAFCOE_00675 7.11e-185 agl 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 31 family
MEPAFCOE_00676 1.69e-231 agl 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 31 family
MEPAFCOE_00677 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 P-type ATPase
MEPAFCOE_00678 0.0 - - CBM50 NU ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MEPAFCOE_00679 4.46e-167 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MEPAFCOE_00680 3.46e-18 - - - - - - - -
MEPAFCOE_00681 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MEPAFCOE_00682 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MEPAFCOE_00683 2e-188 ybbR - - S - - - YbbR-like protein
MEPAFCOE_00684 1.62e-195 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MEPAFCOE_00685 9.08e-157 - - - S - - - Protein of unknown function (DUF1361)
MEPAFCOE_00686 0.0 yvgP - - P ko:K03316 - ko00000 Sodium proton antiporter
MEPAFCOE_00687 2.34e-210 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
MEPAFCOE_00688 3.87e-193 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
MEPAFCOE_00689 6.15e-132 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
MEPAFCOE_00690 1.65e-208 akr5f 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
MEPAFCOE_00691 6.57e-11 - - - K - - - Transcriptional regulator
MEPAFCOE_00692 4.89e-53 - - - K - - - Transcriptional regulator
MEPAFCOE_00693 2.29e-252 adhB 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
MEPAFCOE_00694 9.1e-65 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2316)
MEPAFCOE_00695 1.61e-87 - - - K ko:K18909 - ko00000,ko00002,ko01504,ko03000 MarR family
MEPAFCOE_00696 1.17e-51 - - - K - - - helix_turn_helix, mercury resistance
MEPAFCOE_00697 6.28e-125 - - - GM - - - Male sterility protein
MEPAFCOE_00698 1.57e-233 - - - C - - - Zinc-binding dehydrogenase
MEPAFCOE_00699 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
MEPAFCOE_00700 1.26e-36 yycB - - P ko:K03449 - ko00000,ko02000 Major Facilitator Superfamily
MEPAFCOE_00701 2.16e-247 nhaK - - P ko:K03316 - ko00000 Sodium proton antiporter
MEPAFCOE_00702 1.69e-77 - - - S - - - Belongs to the HesB IscA family
MEPAFCOE_00703 1.76e-225 lctO 1.13.12.4 - C ko:K00467,ko:K10530 ko00620,map00620 ko00000,ko00001,ko01000 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
MEPAFCOE_00704 7.75e-145 - - - K - - - Bacterial regulatory proteins, tetR family
MEPAFCOE_00705 1.51e-248 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
MEPAFCOE_00706 1.36e-157 ybhF_2 - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
MEPAFCOE_00708 6.64e-162 - 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 N-acetylmuramoyl-L-alanine amidase
MEPAFCOE_00709 1.35e-55 - - - S - - - Mor transcription activator family
MEPAFCOE_00710 6.09e-53 - - - S - - - Mor transcription activator family
MEPAFCOE_00711 8.26e-92 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MEPAFCOE_00712 5.12e-132 - - - K - - - Psort location Cytoplasmic, score
MEPAFCOE_00713 0.0 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MEPAFCOE_00714 8.85e-261 - - - - - - - -
MEPAFCOE_00715 1.36e-79 - 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 6-pyruvoyl tetrahydropterin synthase
MEPAFCOE_00716 8.9e-269 icaA - - M - - - Glycosyl transferase family group 2
MEPAFCOE_00717 3.32e-135 - - - - - - - -
MEPAFCOE_00718 2.31e-163 - - - - - - - -
MEPAFCOE_00719 3.32e-77 - - - - - - - -
MEPAFCOE_00720 6.21e-39 yozG - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
MEPAFCOE_00721 8.9e-61 - - - S - - - Protein of unknown function (DUF2975)
MEPAFCOE_00722 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MEPAFCOE_00723 1.22e-36 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
MEPAFCOE_00724 2.96e-198 yitT - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
MEPAFCOE_00725 0.0 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
MEPAFCOE_00726 0.0 potE - - E - - - Amino Acid
MEPAFCOE_00727 1.17e-55 - - - S - - - protein with an alpha beta hydrolase fold
MEPAFCOE_00728 3.73e-176 - - - K - - - Helix-turn-helix
MEPAFCOE_00729 2.99e-45 - - - K - - - Bacterial regulatory proteins, tetR family
MEPAFCOE_00730 1.01e-58 npr 1.11.1.1 - C ko:K05910 - ko00000,ko01000 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain
MEPAFCOE_00731 6.6e-86 - - - - - - - -
MEPAFCOE_00732 1.56e-131 - - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
MEPAFCOE_00733 1.8e-125 - - - S - - - Leucine-rich repeat (LRR) protein
MEPAFCOE_00734 4.71e-238 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MEPAFCOE_00735 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MEPAFCOE_00736 3.79e-308 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MEPAFCOE_00737 2.16e-126 - - - K - - - Bacterial regulatory proteins, tetR family
MEPAFCOE_00738 1.19e-231 - - - D ko:K06889 - ko00000 Alpha beta
MEPAFCOE_00739 3.84e-189 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
MEPAFCOE_00740 1.36e-213 - - - I - - - Alpha beta
MEPAFCOE_00741 0.0 - - - O - - - Pro-kumamolisin, activation domain
MEPAFCOE_00742 6.12e-156 - - - S - - - Membrane
MEPAFCOE_00743 1.19e-173 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
MEPAFCOE_00744 1.68e-50 - - - - - - - -
MEPAFCOE_00745 1.27e-147 nth2 - - L ko:K07457 - ko00000 Base excision DNA repair protein, HhH-GPD family
MEPAFCOE_00746 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MEPAFCOE_00747 1.96e-254 - - - M - - - NlpC/P60 family
MEPAFCOE_00748 3.75e-209 - - - G - - - Peptidase_C39 like family
MEPAFCOE_00749 7.48e-299 - 3.2.1.21, 3.2.1.52 GH3 G ko:K01207,ko:K05349 ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501 ko00000,ko00001,ko00002,ko01000 Fibronectin type III-like domain
MEPAFCOE_00750 6.57e-100 - - - K - - - AraC-like ligand binding domain
MEPAFCOE_00751 6.25e-305 lacZ3 3.2.1.23 - G ko:K01190,ko:K12308 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Beta-galactosidase trimerisation domain
MEPAFCOE_00752 2.39e-196 - - - G - - - MFS/sugar transport protein
MEPAFCOE_00753 4.28e-270 srfJ1 3.2.1.45 GH30 M ko:K01201 ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 30 family
MEPAFCOE_00754 4.83e-136 pncA - - Q - - - Isochorismatase family
MEPAFCOE_00755 1.03e-70 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator PadR-like family
MEPAFCOE_00756 2.1e-117 - - - S - - - Protein of unknown function (DUF1700)
MEPAFCOE_00757 5.39e-194 - - - S - - - Putative adhesin
MEPAFCOE_00758 1.03e-238 dus - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MEPAFCOE_00759 1.78e-285 fabV 1.3.1.44, 1.3.1.9 - I ko:K00209 ko00061,ko00650,ko01100,ko01120,ko01200,ko01212,map00061,map00650,map01100,map01120,map01200,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 NAD(P)H binding domain of trans-2-enoyl-CoA reductase
MEPAFCOE_00760 6.75e-96 - - - C - - - Flavodoxin
MEPAFCOE_00761 2.42e-127 - - - K - - - Acetyltransferase (GNAT) domain
MEPAFCOE_00762 7.74e-315 yifK - - E ko:K03293 - ko00000 Amino acid permease
MEPAFCOE_00763 9.77e-152 - - - - - - - -
MEPAFCOE_00764 8.15e-136 - - - S - - - WxL domain surface cell wall-binding
MEPAFCOE_00765 0.0 - - - S - - - Leucine-rich repeat (LRR) protein
MEPAFCOE_00766 4.77e-289 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
MEPAFCOE_00767 5.52e-241 adhP 1.1.1.1 - C ko:K00001,ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
MEPAFCOE_00768 3.05e-90 - - - K ko:K03719 - ko00000,ko03000,ko03036 AsnC family
MEPAFCOE_00769 2.36e-217 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MEPAFCOE_00770 0.0 - - - EM ko:K05845,ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MEPAFCOE_00771 6.2e-264 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
MEPAFCOE_00772 9.34e-130 - - - S - - - NADPH-dependent FMN reductase
MEPAFCOE_00773 3.92e-110 - - - K - - - MarR family
MEPAFCOE_00774 0.0 pacL1 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
MEPAFCOE_00775 0.0 pepD1 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
MEPAFCOE_00776 1.4e-195 - - - - - - - -
MEPAFCOE_00777 4.42e-136 maa 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
MEPAFCOE_00778 4.01e-153 - - - S - - - Elongation factor G-binding protein, N-terminal
MEPAFCOE_00779 6.76e-214 - - - EG - - - EamA-like transporter family
MEPAFCOE_00780 0.0 copB 3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54 - P ko:K01533,ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
MEPAFCOE_00781 2.86e-102 atkY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor CopY TcrY
MEPAFCOE_00782 6.03e-289 dacA2 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
MEPAFCOE_00783 1.16e-203 morA - - S - - - reductase
MEPAFCOE_00784 0.0 copA 3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54 - P ko:K01533,ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
MEPAFCOE_00785 4.56e-87 - - - S - - - Cupredoxin-like domain
MEPAFCOE_00787 4.19e-202 icaB - - G - - - Polysaccharide deacetylase
MEPAFCOE_00788 1.41e-205 - - - L - - - Phage integrase, N-terminal SAM-like domain
MEPAFCOE_00789 7.85e-242 add 3.5.4.2, 3.5.4.4 - F ko:K01488,ko:K02029,ko:K21053 ko00230,ko01100,ko05340,map00230,map01100,map05340 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MEPAFCOE_00790 0.0 oatA - - I - - - Acyltransferase
MEPAFCOE_00791 9.04e-156 - - - - - - - -
MEPAFCOE_00792 0.0 l1n 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
MEPAFCOE_00793 1.08e-133 - 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
MEPAFCOE_00794 1.38e-89 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
MEPAFCOE_00795 2.11e-49 - - - - - - - -
MEPAFCOE_00796 4.44e-122 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
MEPAFCOE_00797 1.5e-315 xylP1 - - G ko:K03292 - ko00000 MFS/sugar transport protein
MEPAFCOE_00798 1.16e-129 - - - S ko:K08996 - ko00000 Protein of unknown function (DUF1440)
MEPAFCOE_00799 0.0 uvrA2 - - L - - - ABC transporter
MEPAFCOE_00800 5.02e-87 yodA - - S - - - Tautomerase enzyme
MEPAFCOE_00801 0.0 - - - - - - - -
MEPAFCOE_00802 5.73e-300 - - - - - - - -
MEPAFCOE_00803 3.23e-141 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MEPAFCOE_00804 1.74e-224 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MEPAFCOE_00805 1.39e-136 opuCB - - E ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MEPAFCOE_00806 6.99e-199 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MEPAFCOE_00807 5.69e-56 - - - - - - - -
MEPAFCOE_00808 4.19e-282 - - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
MEPAFCOE_00809 8.73e-233 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Peroxidase
MEPAFCOE_00810 1.29e-279 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
MEPAFCOE_00811 1.72e-159 - - - M - - - Protein of unknown function (DUF3737)
MEPAFCOE_00812 0.0 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MEPAFCOE_00813 1.94e-247 ykoT - - M - - - Glycosyl transferase family 2
MEPAFCOE_00814 4.28e-309 - - - M ko:K07273 - ko00000 hydrolase, family 25
MEPAFCOE_00815 1.43e-136 - - - - - - - -
MEPAFCOE_00816 9.86e-264 XK27_05220 - - S - - - AI-2E family transporter
MEPAFCOE_00817 1.66e-265 yclI - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
MEPAFCOE_00818 1.9e-153 vex2 - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
MEPAFCOE_00819 0.0 malL 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
MEPAFCOE_00820 3.54e-178 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
MEPAFCOE_00821 3.29e-206 - - - P - - - CorA-like Mg2+ transporter protein
MEPAFCOE_00822 0.0 pox2 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
MEPAFCOE_00823 3.7e-96 - - - - - - - -
MEPAFCOE_00824 3.02e-57 - - - - - - - -
MEPAFCOE_00825 2.93e-314 hpk2 - - T - - - Histidine kinase
MEPAFCOE_00826 2.6e-167 rrp2 - - K - - - Transcriptional regulatory protein, C terminal
MEPAFCOE_00827 6.24e-53 - - - - - - - -
MEPAFCOE_00828 2.61e-148 - - - GM - - - NAD(P)H-binding
MEPAFCOE_00829 2.28e-292 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
MEPAFCOE_00831 1.25e-119 ogt 2.1.1.63 - L ko:K00567 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MEPAFCOE_00832 7.64e-131 - - - K - - - Bacterial regulatory proteins, tetR family
MEPAFCOE_00833 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
MEPAFCOE_00834 1.11e-127 - - - K - - - Bacterial transcriptional regulator
MEPAFCOE_00835 5.76e-65 - - - G - - - Xylose isomerase domain protein TIM barrel
MEPAFCOE_00836 2.31e-06 - - - - - - - -
MEPAFCOE_00837 1.6e-185 kduI 5.3.1.17 - G ko:K01815 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
MEPAFCOE_00838 5.12e-177 kduD 1.1.1.127 - IQ ko:K00065 ko00040,map00040 ko00000,ko00001,ko01000 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MEPAFCOE_00839 6.39e-164 kdgT - - P ko:K02526 - ko00000,ko02000 2-keto-3-deoxygluconate permease
MEPAFCOE_00840 3.21e-139 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 pfkB family carbohydrate kinase
MEPAFCOE_00841 2.71e-103 eda 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 KDPG and KHG aldolase
MEPAFCOE_00842 1.48e-165 - 1.1.1.53 - IQ ko:K00038 ko00140,ko01100,map00140,map01100 ko00000,ko00001,ko01000 reductase
MEPAFCOE_00843 1.8e-306 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
MEPAFCOE_00844 2.03e-118 - - - S - - - Short repeat of unknown function (DUF308)
MEPAFCOE_00845 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MEPAFCOE_00846 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MEPAFCOE_00847 3.05e-121 - - - K - - - acetyltransferase
MEPAFCOE_00848 3.17e-149 yfbR - - S ko:K07023 - ko00000 HD containing hydrolase-like enzyme
MEPAFCOE_00850 3.26e-226 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MEPAFCOE_00851 1.16e-213 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
MEPAFCOE_00852 2.14e-234 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
MEPAFCOE_00853 2.41e-199 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MEPAFCOE_00854 4.08e-219 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MEPAFCOE_00855 7.21e-50 yvlD - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
MEPAFCOE_00856 5.88e-72 - - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain protein
MEPAFCOE_00857 1.68e-155 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
MEPAFCOE_00858 6.12e-180 pstB1 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MEPAFCOE_00859 5.46e-194 pstB2 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MEPAFCOE_00860 1.68e-198 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
MEPAFCOE_00861 8.95e-201 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
MEPAFCOE_00862 6.18e-205 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
MEPAFCOE_00863 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MEPAFCOE_00864 2.49e-166 phoP - - K ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
MEPAFCOE_00865 5.08e-284 minJ - - O - - - Domain present in PSD-95, Dlg, and ZO-1/2.
MEPAFCOE_00866 9.3e-236 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MEPAFCOE_00867 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MEPAFCOE_00868 3.5e-126 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MEPAFCOE_00869 5.9e-162 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
MEPAFCOE_00870 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
MEPAFCOE_00871 2.39e-147 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
MEPAFCOE_00872 6.19e-243 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 transferase
MEPAFCOE_00873 1.17e-91 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 LrgA family
MEPAFCOE_00874 1.8e-180 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 LrgB-like family
MEPAFCOE_00875 0.0 ydaO - - E - - - amino acid
MEPAFCOE_00876 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MEPAFCOE_00877 1.56e-60 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MEPAFCOE_00878 3.84e-145 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MEPAFCOE_00879 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
MEPAFCOE_00880 3.61e-61 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
MEPAFCOE_00881 9.34e-317 - - - V - - - MatE
MEPAFCOE_00882 7.18e-153 yagB - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
MEPAFCOE_00883 7.01e-213 ybhF_1 - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
MEPAFCOE_00884 0.0 - - - M ko:K01992 - ko00000,ko00002,ko02000 Exporter of polyketide antibiotics
MEPAFCOE_00885 2.12e-78 - - - S - - - 3D domain
MEPAFCOE_00886 3.85e-280 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MEPAFCOE_00887 3.5e-223 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 pfkB family carbohydrate kinase
MEPAFCOE_00888 9.6e-212 kduI 5.3.1.17 - G ko:K01815 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
MEPAFCOE_00889 1.13e-125 - - - K - - - Bacterial regulatory proteins, tetR family
MEPAFCOE_00891 3.71e-76 lysM - - M - - - LysM domain
MEPAFCOE_00893 1.64e-88 - - - M - - - LysM domain protein
MEPAFCOE_00894 0.0 - - - M - - - Leucine-rich repeat (LRR) protein
MEPAFCOE_00895 6.43e-104 - - - M - - - LysM domain protein
MEPAFCOE_00896 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
MEPAFCOE_00897 0.0 glpQ4 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 phosphodiesterase
MEPAFCOE_00898 8.76e-121 - - - K - - - Domain of unknown function (DUF1836)
MEPAFCOE_00899 0.0 yfgQ - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
MEPAFCOE_00900 6.97e-05 - - - - - - - -
MEPAFCOE_00901 2.74e-207 yvgN - - S - - - Aldo keto reductase
MEPAFCOE_00902 0.0 - - - E - - - Amino Acid
MEPAFCOE_00903 1.19e-93 hsp1 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
MEPAFCOE_00904 1.62e-80 - - - - - - - -
MEPAFCOE_00905 4.06e-315 yhdP - - S - - - Transporter associated domain
MEPAFCOE_00906 9.8e-134 - - - S - - - Enoyl-(Acyl carrier protein) reductase
MEPAFCOE_00907 3.04e-68 - - - K - - - transcriptional regulator
MEPAFCOE_00908 1.27e-223 - - - K ko:K02525 - ko00000,ko03000 Transcriptional regulator, LacI family
MEPAFCOE_00909 2.81e-183 kduD 1.1.1.127 - IQ ko:K00065 ko00040,map00040 ko00000,ko00001,ko01000 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MEPAFCOE_00911 8.73e-314 lmrB - - U ko:K18926 - ko00000,ko00002,ko02000 Belongs to the major facilitator superfamily
MEPAFCOE_00912 0.0 - - - S ko:K18231,ko:K19349 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ATPases associated with a variety of cellular activities
MEPAFCOE_00913 2.31e-110 nrdI - - F ko:K03647 - ko00000 Belongs to the NrdI family
MEPAFCOE_00914 1.43e-167 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
MEPAFCOE_00915 6.07e-15 yobV3 - - K - - - Transcriptional regulator
MEPAFCOE_00916 7.88e-26 yobV3 - - K - - - WYL domain
MEPAFCOE_00917 1.42e-218 pmrB - - EGP - - - Major Facilitator Superfamily
MEPAFCOE_00918 2.24e-92 - - - S - - - COG NOG18757 non supervised orthologous group
MEPAFCOE_00920 1.96e-293 - - - EK - - - Aminotransferase, class I
MEPAFCOE_00921 0.0 fusA1 - - J - - - elongation factor G
MEPAFCOE_00922 1.13e-164 - - - F - - - glutamine amidotransferase
MEPAFCOE_00923 1.28e-16 yhaZ - - L - - - DNA alkylation repair enzyme
MEPAFCOE_00924 2.81e-159 yhaZ - - L - - - DNA alkylation repair enzyme
MEPAFCOE_00925 2.48e-159 - - - K - - - UTRA
MEPAFCOE_00926 5.75e-242 - - - O - - - ADP-ribosylglycohydrolase
MEPAFCOE_00927 0.0 - - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
MEPAFCOE_00928 1.31e-210 - - - G - - - Belongs to the carbohydrate kinase PfkB family
MEPAFCOE_00929 1.28e-225 pepI 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
MEPAFCOE_00930 5.23e-170 - - - S - - - Protein of unknown function
MEPAFCOE_00931 1.28e-275 - - - EGP ko:K08196 - ko00000,ko02000 Major Facilitator
MEPAFCOE_00932 6.47e-155 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MEPAFCOE_00933 8.43e-144 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MEPAFCOE_00934 2.8e-173 XK27_08125 - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
MEPAFCOE_00935 0.0 - 3.2.1.45 GH30 G ko:K01201 ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142 ko00000,ko00001,ko01000 Glycosyl hydrolase family 30 TIM-barrel domain
MEPAFCOE_00936 1.24e-201 - - - K - - - Transcriptional regulator
MEPAFCOE_00937 4.68e-09 - - - S - - - Protein of unknown function (DUF2992)
MEPAFCOE_00938 7.18e-43 - - - S - - - Transglycosylase associated protein
MEPAFCOE_00939 2.5e-52 - - - - - - - -
MEPAFCOE_00940 0.0 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
MEPAFCOE_00941 2.5e-201 - - - EG - - - EamA-like transporter family
MEPAFCOE_00942 7.56e-36 - - - - - - - -
MEPAFCOE_00943 1.47e-265 atoB 1.1.1.88, 2.3.1.9 - I ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
MEPAFCOE_00944 9.7e-252 ptcA 2.1.3.6 - E ko:K13252 - ko00000,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MEPAFCOE_00945 6.03e-306 aguD - - E ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 Amino Acid
MEPAFCOE_00946 8.96e-277 aguA 3.5.3.12 - E ko:K10536 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko01000 agmatine deiminase
MEPAFCOE_00947 2.85e-216 arcC 2.7.2.2 - E ko:K00926 ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200 ko00000,ko00001,ko01000 Belongs to the carbamate kinase family
MEPAFCOE_00948 1.01e-276 aguA2 3.5.3.12 - E ko:K10536 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko01000 agmatine deiminase
MEPAFCOE_00949 5.05e-192 - - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
MEPAFCOE_00950 3.19e-208 mleR - - K - - - LysR family
MEPAFCOE_00951 0.0 mleS 1.1.1.38, 4.1.1.101 - C ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme
MEPAFCOE_00952 4.7e-215 mleP2 - - S ko:K07088 - ko00000 Sodium Bile acid symporter family
MEPAFCOE_00953 3.2e-107 thiW - - S - - - Thiamine-precursor transporter protein (ThiW)
MEPAFCOE_00954 8.28e-249 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MEPAFCOE_00955 2.73e-140 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 Ribosomal-protein-alanine acetyltransferase
MEPAFCOE_00956 7.6e-159 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
MEPAFCOE_00957 1.15e-181 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
MEPAFCOE_00958 1.68e-201 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MEPAFCOE_00959 3.21e-62 yabA - - L - - - Involved in initiation control of chromosome replication
MEPAFCOE_00960 1.04e-225 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
MEPAFCOE_00961 5.88e-72 yaaQ - - S - - - Cyclic-di-AMP receptor
MEPAFCOE_00962 7.16e-141 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MEPAFCOE_00963 2.48e-52 yaaL - - S - - - Protein of unknown function (DUF2508)
MEPAFCOE_00964 1.31e-141 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MEPAFCOE_00965 9.59e-58 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MEPAFCOE_00966 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MEPAFCOE_00967 1.09e-123 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MEPAFCOE_00968 3.89e-145 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
MEPAFCOE_00969 9.51e-51 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
MEPAFCOE_00970 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MEPAFCOE_00971 4.42e-249 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MEPAFCOE_00972 1.08e-215 - 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 3-hydroxyacyl-CoA dehydrogenase
MEPAFCOE_00973 7.64e-142 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
MEPAFCOE_00974 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MEPAFCOE_00975 7.9e-74 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MEPAFCOE_00976 3.73e-110 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MEPAFCOE_00977 1.75e-160 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MEPAFCOE_00978 4.14e-94 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MEPAFCOE_00979 1.61e-127 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
MEPAFCOE_00980 3.64e-34 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MEPAFCOE_00981 2.97e-122 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Sigma-70 region 2
MEPAFCOE_00982 7.3e-117 yacP - - S ko:K06962 - ko00000 YacP-like NYN domain
MEPAFCOE_00983 5.21e-178 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MEPAFCOE_00984 7.28e-92 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MEPAFCOE_00985 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
MEPAFCOE_00986 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MEPAFCOE_00987 3e-272 yacL - - S - - - domain protein
MEPAFCOE_00988 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MEPAFCOE_00989 2.6e-129 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
MEPAFCOE_00990 1.42e-74 - - - - - - - -
MEPAFCOE_00991 1.63e-163 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MEPAFCOE_00993 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
MEPAFCOE_00994 5.86e-294 - - - V - - - Beta-lactamase
MEPAFCOE_00995 8.39e-159 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MEPAFCOE_00996 5.41e-231 - - - EG - - - EamA-like transporter family
MEPAFCOE_00997 5.71e-212 mleP2 - - S ko:K07088 - ko00000 Transporter, auxin efflux carrier (AEC) family protein
MEPAFCOE_00998 3.7e-259 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
MEPAFCOE_00999 4.58e-217 psaA - - P ko:K02077,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
MEPAFCOE_01000 0.0 XK27_06930 - - V ko:K01421 - ko00000 domain protein
MEPAFCOE_01001 2.02e-131 - - - K - - - Bacterial regulatory proteins, tetR family
MEPAFCOE_01002 3.3e-152 - - - T - - - Putative diguanylate phosphodiesterase
MEPAFCOE_01003 4.82e-211 - - - T - - - diguanylate cyclase
MEPAFCOE_01004 1.94e-226 ydbI - - K - - - AI-2E family transporter
MEPAFCOE_01005 2.4e-193 manN - - G ko:K02796,ko:K02815 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
MEPAFCOE_01006 4.4e-173 manM - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system
MEPAFCOE_01007 8.55e-79 manX 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
MEPAFCOE_01008 5.33e-71 levD 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11194 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
MEPAFCOE_01009 3.3e-137 - - - S - - - HAD hydrolase, family IA, variant
MEPAFCOE_01010 3.81e-310 dinF - - V - - - MatE
MEPAFCOE_01011 6.05e-98 - - - K - - - MarR family
MEPAFCOE_01012 3.74e-130 - - - S - - - Psort location CytoplasmicMembrane, score
MEPAFCOE_01013 4.99e-81 - - - K - - - transcriptional regulator
MEPAFCOE_01014 1.21e-156 - - - S - - - Alpha/beta hydrolase family
MEPAFCOE_01015 5.63e-191 - 4.1.1.52 - S ko:K22213 - ko00000,ko01000 Amidohydrolase
MEPAFCOE_01017 3.42e-202 thrB 2.7.1.39 - F ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MEPAFCOE_01018 1.75e-115 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
MEPAFCOE_01019 0.0 tex - - K ko:K06959 - ko00000 Tex-like protein N-terminal domain protein
MEPAFCOE_01020 3e-93 - - - - ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 -
MEPAFCOE_01021 7.76e-195 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MEPAFCOE_01022 0.0 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MEPAFCOE_01023 1.29e-178 tagA 2.4.1.187 GT26 F ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
MEPAFCOE_01024 9.21e-120 yfbM - - K - - - FR47-like protein
MEPAFCOE_01025 2.79e-162 yvoA_2 - - K ko:K03710 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
MEPAFCOE_01026 1.56e-276 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
MEPAFCOE_01027 1.15e-171 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MEPAFCOE_01030 5.29e-193 - - - S - - - Calcineurin-like phosphoesterase
MEPAFCOE_01031 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
MEPAFCOE_01032 4.54e-70 - 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
MEPAFCOE_01034 7.06e-102 - 2.4.2.6 - F ko:K08728 ko00240,map00240 ko00000,ko00001,ko01000 Nucleoside 2-deoxyribosyltransferase
MEPAFCOE_01035 9.36e-111 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
MEPAFCOE_01036 0.0 ydbT - - S ko:K08981 - ko00000 Bacterial PH domain
MEPAFCOE_01037 4.84e-242 nhaP4 - - P ko:K03316 - ko00000 Sodium proton antiporter
MEPAFCOE_01038 3.08e-264 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
MEPAFCOE_01039 2e-272 yojA - - EG ko:K03299 - ko00000,ko02000 GntP family permease
MEPAFCOE_01040 1.94e-246 - - - KT ko:K02647 - ko00000,ko03000 Putative sugar diacid recognition
MEPAFCOE_01041 4.11e-224 - - - - ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
MEPAFCOE_01042 2.52e-206 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MEPAFCOE_01043 2.63e-82 ytrA - - K ko:K07979 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
MEPAFCOE_01044 6.56e-164 - - - S - - - Protein of unknown function (DUF975)
MEPAFCOE_01045 3.69e-169 - - - S - - - B3/4 domain
MEPAFCOE_01046 0.0 - 2.8.2.22 - M ko:K01023 - ko00000,ko01000 Arylsulfotransferase Ig-like domain
MEPAFCOE_01047 7.27e-42 - - - - - - - -
MEPAFCOE_01048 2.5e-230 iunH5 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 inosine-uridine preferring nucleoside hydrolase
MEPAFCOE_01049 9.86e-210 oroP - - S ko:K09936 ko02024,map02024 ko00000,ko00001,ko02000 Putative inner membrane exporter, YdcZ
MEPAFCOE_01050 0.0 ykpA - - S - - - ABC transporter, ATP-binding protein
MEPAFCOE_01051 8.24e-87 - - - K - - - helix_turn_helix, arabinose operon control protein
MEPAFCOE_01052 4.15e-96 - - - K - - - helix_turn_helix, arabinose operon control protein
MEPAFCOE_01053 3.08e-52 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 transporter
MEPAFCOE_01054 2.83e-190 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 transporter
MEPAFCOE_01055 2.89e-195 - - - K - - - LysR substrate binding domain
MEPAFCOE_01056 3.87e-208 - - - S - - - Conserved hypothetical protein 698
MEPAFCOE_01057 2.63e-128 cadD - - P - - - Cadmium resistance transporter
MEPAFCOE_01058 2.02e-69 czrA - - K ko:K22043 - ko00000,ko03000 Transcriptional regulator, ArsR family
MEPAFCOE_01059 0.0 sufI - - Q - - - Multicopper oxidase
MEPAFCOE_01060 1.49e-154 - - - S - - - SNARE associated Golgi protein
MEPAFCOE_01061 0.0 cadA - - P - - - P-type ATPase
MEPAFCOE_01062 3.87e-263 - - - M - - - Collagen binding domain
MEPAFCOE_01063 3.22e-90 - - - S - - - Iron-sulphur cluster biosynthesis
MEPAFCOE_01064 5.55e-79 - - - K - - - Transcriptional regulator, GntR family
MEPAFCOE_01065 0.0 - - - Q ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
MEPAFCOE_01066 1.14e-175 cysA - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MEPAFCOE_01067 3.04e-233 ydhF - - S - - - Aldo keto reductase
MEPAFCOE_01068 1.08e-256 ydiC1 - - EGP - - - Major Facilitator
MEPAFCOE_01069 0.0 ydgH - - S ko:K06994 - ko00000 MMPL family
MEPAFCOE_01070 2.21e-21 - - - - - - - -
MEPAFCOE_01071 9.28e-171 - 1.1.1.304, 1.1.1.76 - IQ ko:K03366 ko00650,map00650 ko00000,ko00001,ko01000 reductase
MEPAFCOE_01072 1.16e-241 - 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MEPAFCOE_01073 2.59e-231 - - - S - - - DUF218 domain
MEPAFCOE_01074 1.77e-143 acmA - - NU - - - mannosyl-glycoprotein
MEPAFCOE_01075 1.54e-305 - 3.4.16.4 - V ko:K01286 - ko00000,ko01000 SH3-like domain
MEPAFCOE_01076 4.93e-164 - - - P - - - integral membrane protein, YkoY family
MEPAFCOE_01077 1.2e-204 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 Dehydrogenase
MEPAFCOE_01079 1.49e-282 - - - - - - - -
MEPAFCOE_01081 1.53e-146 - - - S - - - Fn3-like domain
MEPAFCOE_01082 8.39e-73 - - - S - - - WxL domain surface cell wall-binding
MEPAFCOE_01083 4.05e-81 - - - S - - - WxL domain surface cell wall-binding
MEPAFCOE_01084 1.61e-177 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MEPAFCOE_01085 2.56e-196 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
MEPAFCOE_01086 4.81e-228 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
MEPAFCOE_01087 6.68e-206 - - - S - - - Uncharacterised protein, DegV family COG1307
MEPAFCOE_01088 4.03e-215 XK27_00670 - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
MEPAFCOE_01089 4.03e-215 WQ51_06230 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
MEPAFCOE_01090 3.97e-156 - - - S ko:K05833 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
MEPAFCOE_01091 1.19e-161 XK27_07075 - - S ko:K07052 - ko00000 CAAX protease self-immunity
MEPAFCOE_01092 1.57e-89 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MEPAFCOE_01093 0.0 - - - S - - - ABC transporter, ATP-binding protein
MEPAFCOE_01094 4.19e-113 yciB - - M - - - ErfK YbiS YcfS YnhG
MEPAFCOE_01095 3.67e-227 - 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
MEPAFCOE_01096 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
MEPAFCOE_01097 0.0 yhdG - - E ko:K03294 - ko00000 Amino Acid
MEPAFCOE_01098 3.55e-99 apfA 3.6.1.61 - F ko:K18445 ko00230,map00230 ko00000,ko00001,ko01000 Nudix hydrolase
MEPAFCOE_01099 1.3e-97 gmk2 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Guanylate kinase
MEPAFCOE_01100 1.57e-198 degV - - S - - - Uncharacterised protein, DegV family COG1307
MEPAFCOE_01101 0.0 nox - - C - - - NADH oxidase
MEPAFCOE_01102 6.89e-75 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
MEPAFCOE_01103 2.72e-51 yrkD - - S - - - Metal-sensitive transcriptional repressor
MEPAFCOE_01104 3.13e-86 crcB1 - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MEPAFCOE_01105 1.82e-77 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MEPAFCOE_01106 8.33e-193 - - - - - - - -
MEPAFCOE_01107 2.01e-210 - - - I - - - Carboxylesterase family
MEPAFCOE_01108 1.44e-113 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MEPAFCOE_01109 2.67e-209 - - - - - - - -
MEPAFCOE_01110 0.0 pts14C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MEPAFCOE_01111 1.08e-216 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
MEPAFCOE_01112 4.53e-203 lysR5 - - K - - - LysR substrate binding domain
MEPAFCOE_01113 6.23e-183 - - - S ko:K07090 - ko00000 membrane transporter protein
MEPAFCOE_01114 2.42e-74 - - - S - - - Protein of unknown function (DUF1634)
MEPAFCOE_01115 7.15e-179 - - - IQ - - - Oxidoreductase, short chain dehydrogenase reductase family protein
MEPAFCOE_01116 1.43e-290 mdtG - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
MEPAFCOE_01117 4.89e-121 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
MEPAFCOE_01118 2.36e-38 - - - S - - - Protein of unknown function (DUF2929)
MEPAFCOE_01119 3.7e-224 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MEPAFCOE_01121 0.0 - - - S - - - membrane
MEPAFCOE_01122 4.29e-160 ciaR - - K ko:K14983 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 cheY-homologous receiver domain
MEPAFCOE_01123 5.25e-313 ciaH 2.7.13.3 - T ko:K14982 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 His Kinase A (phosphoacceptor) domain
MEPAFCOE_01124 3.99e-231 malR1 - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
MEPAFCOE_01125 0.0 malT - - G ko:K16211 - ko00000,ko02000 Major Facilitator
MEPAFCOE_01126 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
MEPAFCOE_01127 3.12e-100 - - - - - - - -
MEPAFCOE_01128 5.85e-56 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MEPAFCOE_01129 1.31e-190 galM1 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
MEPAFCOE_01130 4.22e-207 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
MEPAFCOE_01131 1.91e-193 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
MEPAFCOE_01132 1.7e-84 - - - K - - - MarR family
MEPAFCOE_01133 0.0 - - - M - - - Parallel beta-helix repeats
MEPAFCOE_01135 1.23e-117 - - - S - - - Cob(I)alamin adenosyltransferase
MEPAFCOE_01136 0.0 rtpR 1.17.4.2 - F ko:K00527 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 ribonucleoside-triphosphate reductase activity
MEPAFCOE_01138 5.92e-236 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
MEPAFCOE_01139 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
MEPAFCOE_01140 5.36e-247 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
MEPAFCOE_01141 1.76e-277 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MEPAFCOE_01142 0.0 lacP - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
MEPAFCOE_01143 1.71e-49 - - - - - - - -
MEPAFCOE_01144 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
MEPAFCOE_01145 3.63e-248 galM1 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
MEPAFCOE_01146 8.79e-263 - 1.3.8.1, 1.3.8.7 - I ko:K00248,ko:K00249,ko:K18244 ko00071,ko00280,ko00410,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map00650,map01100,map01110,map01120,map01130,map01200,map01212,map03320 ko00000,ko00001,ko00002,ko01000 Acyl-CoA dehydrogenase, C-terminal domain
MEPAFCOE_01147 5.62e-182 fixA - - C ko:K03521 - ko00000 Electron transfer flavoprotein domain
MEPAFCOE_01148 1.74e-225 etfA 1.3.1.108 - C ko:K03522,ko:K22432 - ko00000,ko01000,ko04147 Electron transfer flavoprotein FAD-binding domain
MEPAFCOE_01149 1.02e-232 - 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 nadph quinone reductase
MEPAFCOE_01150 2.1e-71 - - - K - - - Transcriptional
MEPAFCOE_01151 4.85e-159 - - - S - - - DJ-1/PfpI family
MEPAFCOE_01152 0.0 - - - EP - - - Psort location Cytoplasmic, score
MEPAFCOE_01153 7.57e-97 - - - K - - - Transcriptional regulator, LysR family
MEPAFCOE_01154 3.17e-242 - - - G ko:K08177 - ko00000,ko02000 Major Facilitator Superfamily
MEPAFCOE_01155 5.13e-164 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MEPAFCOE_01156 1.96e-168 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
MEPAFCOE_01157 2.02e-106 - - - S - - - ASCH
MEPAFCOE_01158 5.31e-316 - - - EGP - - - Major Facilitator
MEPAFCOE_01159 3.29e-32 - - - - - - - -
MEPAFCOE_01160 3.31e-195 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
MEPAFCOE_01161 3.43e-179 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
MEPAFCOE_01163 1.07e-120 - - - I - - - NUDIX domain
MEPAFCOE_01164 1.18e-94 yviA - - S - - - Protein of unknown function (DUF421)
MEPAFCOE_01165 4.02e-23 yviA - - S - - - Protein of unknown function (DUF421)
MEPAFCOE_01166 1.21e-94 - - - S - - - Protein of unknown function (DUF3290)
MEPAFCOE_01167 8.13e-206 ropB - - K - - - Helix-turn-helix XRE-family like proteins
MEPAFCOE_01168 2.36e-273 - - - EGP - - - Transmembrane secretion effector
MEPAFCOE_01169 0.0 gshR 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
MEPAFCOE_01170 2.98e-49 ygbF - - S - - - Sugar efflux transporter for intercellular exchange
MEPAFCOE_01172 6.83e-257 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MEPAFCOE_01173 5.37e-48 - - - - - - - -
MEPAFCOE_01174 3.02e-174 - - - G - - - Xylose isomerase domain protein TIM barrel
MEPAFCOE_01175 3.58e-291 gntT - - EG - - - Citrate transporter
MEPAFCOE_01176 5.62e-226 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 pfkB family carbohydrate kinase
MEPAFCOE_01177 5.45e-138 - 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Orotidine 5'-phosphate decarboxylase HUMPS family
MEPAFCOE_01178 2.02e-113 hxlB 5.3.1.27 - M ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 sugar phosphate isomerase involved in capsule formation
MEPAFCOE_01179 1.05e-225 kdgR - - K ko:K02525 - ko00000,ko03000 helix_turn _helix lactose operon repressor
MEPAFCOE_01180 2.33e-108 - - - - - - - -
MEPAFCOE_01181 0.0 - - - L - - - DNA helicase
MEPAFCOE_01182 1.16e-243 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
MEPAFCOE_01183 2.2e-131 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
MEPAFCOE_01184 1.38e-55 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
MEPAFCOE_01185 7.25e-284 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
MEPAFCOE_01186 1.23e-225 - - - - - - - -
MEPAFCOE_01187 1.69e-167 cobB - - K ko:K12410 - ko00000,ko01000 SIR2 family
MEPAFCOE_01188 8.41e-67 - - - - - - - -
MEPAFCOE_01189 6.98e-205 yunF - - F - - - Protein of unknown function DUF72
MEPAFCOE_01190 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MEPAFCOE_01191 2.71e-186 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
MEPAFCOE_01192 9.98e-128 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MEPAFCOE_01193 4.9e-208 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MEPAFCOE_01194 1.14e-48 veg - - S - - - Biofilm formation stimulator VEG
MEPAFCOE_01195 3.2e-207 ispE 2.7.1.148 - F ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MEPAFCOE_01196 0.0 - - - G ko:K03292 - ko00000 MFS/sugar transport protein
MEPAFCOE_01197 0.0 - 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 31 family
MEPAFCOE_01198 3.1e-209 - - - EG ko:K16321 - ko00000,ko02000 GntP family permease
MEPAFCOE_01199 1.7e-104 eda 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 KDPG and KHG aldolase
MEPAFCOE_01200 2.17e-135 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 pfkB family carbohydrate kinase
MEPAFCOE_01201 5.33e-305 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
MEPAFCOE_01202 1.15e-46 - - - - - - - -
MEPAFCOE_01203 0.0 uxuT - - G ko:K03292,ko:K16210 - ko00000,ko02000 MFS/sugar transport protein
MEPAFCOE_01204 7.56e-119 kdgR - - K - - - FCD domain
MEPAFCOE_01205 1.76e-257 uxuA 4.2.1.8 - G ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of D-mannonate
MEPAFCOE_01206 0.0 uxuB 1.1.1.57 - G ko:K00040 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Mannitol dehydrogenase C-terminal domain
MEPAFCOE_01207 1.12e-211 yqhA - - G - - - Aldose 1-epimerase
MEPAFCOE_01208 1.19e-152 - - - G - - - Belongs to the phosphoglycerate mutase family
MEPAFCOE_01209 1.41e-240 - - - C - - - Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MEPAFCOE_01210 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
MEPAFCOE_01211 2.36e-217 gntZ 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
MEPAFCOE_01212 3.54e-165 - - - K - - - FCD domain
MEPAFCOE_01213 9.16e-266 uxuA 4.2.1.8 - G ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of D-mannonate
MEPAFCOE_01214 2.14e-233 exuR - - K ko:K02529 - ko00000,ko03000 Periplasmic binding protein domain
MEPAFCOE_01215 0.0 - - - G ko:K03292 - ko00000 MFS/sugar transport protein
MEPAFCOE_01216 0.0 - 5.1.2.7 - S ko:K21619 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 tagaturonate epimerase
MEPAFCOE_01217 0.0 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
MEPAFCOE_01218 1.37e-289 - - - S - - - module of peptide synthetase
MEPAFCOE_01220 0.0 - - - EGP - - - Major Facilitator
MEPAFCOE_01223 7.28e-175 - - - - - - - -
MEPAFCOE_01224 5.77e-118 ebsC - - J ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MEPAFCOE_01225 3.02e-170 gntR1 - - K - - - UbiC transcription regulator-associated domain protein
MEPAFCOE_01226 4.33e-161 zmp3 - - O - - - Zinc-dependent metalloprotease
MEPAFCOE_01227 1.68e-109 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MEPAFCOE_01228 6.37e-102 - - - - - - - -
MEPAFCOE_01229 2.4e-181 agrA - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
MEPAFCOE_01230 1.53e-304 pltK 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
MEPAFCOE_01231 8.52e-281 - - - T - - - protein histidine kinase activity
MEPAFCOE_01232 3.97e-173 - - - IQ - - - Oxidoreductase, short chain dehydrogenase reductase family protein
MEPAFCOE_01234 6.32e-224 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
MEPAFCOE_01235 4.19e-101 uspA3 - - T - - - universal stress protein
MEPAFCOE_01236 8.87e-49 - - - EGP - - - Major Facilitator
MEPAFCOE_01237 2.3e-150 - - - EGP - - - Major Facilitator
MEPAFCOE_01238 1.55e-64 - - - K - - - transcriptional regulator
MEPAFCOE_01239 0.0 oppA1 - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
MEPAFCOE_01240 3.95e-224 oppC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MEPAFCOE_01241 1.14e-229 oppB - - P ko:K02033,ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MEPAFCOE_01242 5.64e-228 oppF - - P ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MEPAFCOE_01243 1.08e-243 oppD - - P ko:K02031,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MEPAFCOE_01244 4.5e-102 - - - K - - - Winged helix-turn-helix transcription repressor, HrcA DNA-binding
MEPAFCOE_01245 6.45e-244 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
MEPAFCOE_01246 8.07e-91 - - - - - - - -
MEPAFCOE_01247 2.68e-62 - - - - - - - -
MEPAFCOE_01248 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
MEPAFCOE_01249 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Xylulose kinase
MEPAFCOE_01250 5.73e-288 xylT - - EGP - - - Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MEPAFCOE_01252 7.71e-182 budC 1.1.1.304, 1.1.1.76 - IQ ko:K03366 ko00650,map00650 ko00000,ko00001,ko01000 reductase
MEPAFCOE_01253 5.97e-79 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
MEPAFCOE_01254 6.65e-137 - - - S - - - membrane
MEPAFCOE_01255 0.0 - - - S - - - membrane
MEPAFCOE_01256 1.06e-116 usp5 - - T - - - universal stress protein
MEPAFCOE_01257 2.26e-125 yxkA - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
MEPAFCOE_01258 2.14e-279 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
MEPAFCOE_01259 3.72e-160 - - - P ko:K10716 - ko00000,ko02000 Ion channel
MEPAFCOE_01260 2.16e-77 - - - - - - - -
MEPAFCOE_01261 7.25e-216 - - - C - - - Aldo keto reductase
MEPAFCOE_01262 5.43e-91 - - - - - - - -
MEPAFCOE_01263 1.9e-121 - - - S - - - Acetyltransferase (GNAT) family
MEPAFCOE_01264 0.0 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
MEPAFCOE_01265 2.42e-241 - - - S ko:K07088 - ko00000 Membrane transport protein
MEPAFCOE_01266 2.17e-241 idhA 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MEPAFCOE_01267 0.0 yufL 2.7.13.3 - T ko:K02476,ko:K11614 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Single cache domain 3
MEPAFCOE_01268 6.8e-161 dctR - - K ko:K02475,ko:K11692 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 cheY-homologous receiver domain
MEPAFCOE_01269 3.66e-280 - - - S - - - ABC-2 family transporter protein
MEPAFCOE_01270 8.52e-130 - - - K - - - Bacterial regulatory proteins, tetR family
MEPAFCOE_01271 2.83e-159 - - - T - - - Putative diguanylate phosphodiesterase
MEPAFCOE_01272 2.24e-123 - - - K - - - Acetyltransferase (GNAT) family
MEPAFCOE_01273 9.87e-183 - - - S - - - zinc-ribbon domain
MEPAFCOE_01274 0.0 - - - S - - - response to antibiotic
MEPAFCOE_01275 4.33e-109 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
MEPAFCOE_01277 4.36e-87 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
MEPAFCOE_01278 1.64e-108 padR - - K - - - Virulence activator alpha C-term
MEPAFCOE_01279 2.28e-132 - - - K - - - Bacterial regulatory proteins, tetR family
MEPAFCOE_01280 5.2e-232 - 1.1.1.219 - GM ko:K00091 - ko00000,ko01000 Male sterility protein
MEPAFCOE_01281 4.95e-98 - - - S ko:K02348 - ko00000 Gnat family
MEPAFCOE_01282 5.75e-103 yybA - - K - - - Transcriptional regulator
MEPAFCOE_01286 4.26e-24 - - - K ko:K20375 ko02024,map02024 ko00000,ko00001,ko03000 Transcriptional activator, Rgg GadR MutR family
MEPAFCOE_01290 1.51e-250 - - - M - - - domain protein
MEPAFCOE_01291 5.05e-184 - - - K - - - Helix-turn-helix domain
MEPAFCOE_01292 9.98e-215 - - - - - - - -
MEPAFCOE_01293 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
MEPAFCOE_01294 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
MEPAFCOE_01295 7.71e-277 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
MEPAFCOE_01296 2.61e-235 pgdA 3.5.1.104 - G ko:K22278 - ko00000,ko01000 polysaccharide deacetylase
MEPAFCOE_01297 3.66e-77 - - - - - - - -
MEPAFCOE_01298 1.58e-133 - - - GM - - - NAD(P)H-binding
MEPAFCOE_01299 1.1e-231 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
MEPAFCOE_01300 1e-289 pbuG - - S ko:K06901 - ko00000,ko02000 permease
MEPAFCOE_01301 4.15e-120 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
MEPAFCOE_01302 1.32e-199 drrA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
MEPAFCOE_01303 5.93e-165 drrB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
MEPAFCOE_01304 4.28e-128 - - - K - - - LysR substrate binding domain
MEPAFCOE_01305 9.97e-87 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
MEPAFCOE_01306 2.97e-213 - 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 UbiA prenyltransferase family
MEPAFCOE_01307 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
MEPAFCOE_01308 1.39e-112 ccl - - S - - - QueT transporter
MEPAFCOE_01312 1.15e-94 - - - K - - - helix_turn_helix, mercury resistance
MEPAFCOE_01313 5.42e-169 gntR - - K - - - UbiC transcription regulator-associated domain protein
MEPAFCOE_01314 0.0 xpkA 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
MEPAFCOE_01315 3.14e-187 yxeH - - S - - - hydrolase
MEPAFCOE_01316 0.0 ywfO - - S ko:K06885 - ko00000 HD domain protein
MEPAFCOE_01317 2.61e-199 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 biotin lipoate A B protein ligase
MEPAFCOE_01318 1.22e-102 ywiB - - S - - - Domain of unknown function (DUF1934)
MEPAFCOE_01319 3.8e-78 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MEPAFCOE_01320 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MEPAFCOE_01321 0.0 - - - S - - - Leucine-rich repeat (LRR) protein
MEPAFCOE_01322 7.74e-299 - - - - - - - -
MEPAFCOE_01323 9.42e-95 - - - K - - - Transcriptional regulator
MEPAFCOE_01324 0.0 spxB 1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8 - EH ko:K00156,ko:K00158,ko:K01577,ko:K01652 ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
MEPAFCOE_01325 2.02e-157 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Belongs to the alpha-acetolactate decarboxylase family
MEPAFCOE_01326 8.25e-168 - - - M - - - LPXTG-motif cell wall anchor domain protein
MEPAFCOE_01328 1.29e-297 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MEPAFCOE_01329 3.24e-57 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
MEPAFCOE_01330 2.17e-152 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
MEPAFCOE_01334 1.77e-165 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
MEPAFCOE_01335 4.49e-151 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
MEPAFCOE_01336 1.94e-215 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MEPAFCOE_01337 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
MEPAFCOE_01338 6.05e-169 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
MEPAFCOE_01339 1.7e-314 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MEPAFCOE_01340 3.11e-220 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MEPAFCOE_01341 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MEPAFCOE_01342 1.09e-274 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MEPAFCOE_01343 2.53e-42 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MEPAFCOE_01344 2.35e-134 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
MEPAFCOE_01345 2.72e-67 - - - - - - - -
MEPAFCOE_01347 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
MEPAFCOE_01348 9.88e-100 argR2 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
MEPAFCOE_01349 1.62e-189 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
MEPAFCOE_01350 5.49e-207 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
MEPAFCOE_01351 6.72e-47 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MEPAFCOE_01352 3.68e-311 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MEPAFCOE_01353 3.85e-201 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MEPAFCOE_01354 2.79e-97 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MEPAFCOE_01355 8.9e-96 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
MEPAFCOE_01356 5.18e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MEPAFCOE_01357 6.82e-251 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
MEPAFCOE_01358 8.46e-65 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
MEPAFCOE_01359 7.92e-76 ysxB - - J ko:K07584 - ko00000 Cysteine protease Prp
MEPAFCOE_01360 5.22e-65 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
MEPAFCOE_01361 3.43e-123 - - - K - - - Transcriptional regulator
MEPAFCOE_01362 1.05e-124 - - - S - - - Protein conserved in bacteria
MEPAFCOE_01363 7.15e-230 - - - - - - - -
MEPAFCOE_01364 1.83e-200 - - - - - - - -
MEPAFCOE_01365 6.01e-304 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
MEPAFCOE_01366 1.38e-274 hpk31 - - T - - - Histidine kinase
MEPAFCOE_01367 4.64e-159 vanR - - K - - - response regulator
MEPAFCOE_01368 1.42e-267 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MEPAFCOE_01369 3.1e-138 - - - - - - - -
MEPAFCOE_01370 2.48e-170 - - - S - - - Protein of unknown function (DUF1129)
MEPAFCOE_01371 2.3e-255 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MEPAFCOE_01372 3.3e-43 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
MEPAFCOE_01373 1.44e-199 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
MEPAFCOE_01374 3.52e-176 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
MEPAFCOE_01375 5.86e-191 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
MEPAFCOE_01376 2.3e-170 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
MEPAFCOE_01377 7.03e-213 - 3.1.4.17, 3.1.4.53 - S ko:K01120,ko:K03651 ko00230,ko02025,map00230,map02025 ko00000,ko00001,ko01000 Calcineurin-like phosphoesterase
MEPAFCOE_01378 5.58e-218 rihA 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
MEPAFCOE_01379 7.77e-283 pbuO_1 - - S ko:K06901 - ko00000,ko02000 Permease family
MEPAFCOE_01380 4.23e-287 nupG - - F ko:K16323 - ko00000,ko02000 Nucleoside
MEPAFCOE_01381 1.03e-198 - 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Metalloenzyme superfamily
MEPAFCOE_01382 2.4e-144 - - - GM - - - NmrA-like family
MEPAFCOE_01383 4.83e-59 - - - - - - - -
MEPAFCOE_01384 1.3e-124 - - - - - - - -
MEPAFCOE_01385 6.01e-54 - - - - - - - -
MEPAFCOE_01386 2.61e-83 - - - K - - - HxlR-like helix-turn-helix
MEPAFCOE_01388 1.91e-150 - - - - - - - -
MEPAFCOE_01391 2.64e-215 tas - - C - - - Aldo/keto reductase family
MEPAFCOE_01392 1.85e-82 - - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 glycine cleavage
MEPAFCOE_01393 7.02e-245 - 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
MEPAFCOE_01394 2.47e-68 - - - - - - - -
MEPAFCOE_01395 0.0 - - - M - - - domain, Protein
MEPAFCOE_01396 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
MEPAFCOE_01397 3.84e-281 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific adenine glycosylase
MEPAFCOE_01398 2.63e-69 - - - - - - - -
MEPAFCOE_01399 1.41e-142 mhqD - - S ko:K06999 - ko00000 Dienelactone hydrolase family
MEPAFCOE_01400 2.32e-43 cspC - - K ko:K03704 - ko00000,ko03000 Cold shock protein
MEPAFCOE_01401 1.04e-49 - - - S - - - Cytochrome B5
MEPAFCOE_01403 1.76e-44 - - - - - - - -
MEPAFCOE_01405 4.12e-158 yrkL - - S - - - Flavodoxin-like fold
MEPAFCOE_01406 8.02e-25 - - - - - - - -
MEPAFCOE_01407 8.74e-194 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
MEPAFCOE_01408 9.2e-64 - - - - - - - -
MEPAFCOE_01409 7.25e-305 codA 3.5.4.1 - F ko:K01485 ko00240,ko00330,ko01100,map00240,map00330,map01100 ko00000,ko00001,ko01000 cytosine deaminase
MEPAFCOE_01410 1.89e-110 - - - - - - - -
MEPAFCOE_01411 4.49e-188 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MEPAFCOE_01412 5.2e-108 - - - S ko:K04750 - ko00000 3-demethylubiquinone-9 3-methyltransferase
MEPAFCOE_01413 1.53e-146 maa 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
MEPAFCOE_01414 0.0 - - - U ko:K03451 - ko00000 Belongs to the BCCT transporter (TC 2.A.15) family
MEPAFCOE_01415 2.33e-103 - - - T - - - Universal stress protein family
MEPAFCOE_01416 3.02e-160 - - - S - - - HAD-hyrolase-like
MEPAFCOE_01417 1.01e-91 yeaO - - S - - - Protein of unknown function, DUF488
MEPAFCOE_01418 1.35e-153 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
MEPAFCOE_01419 1.99e-201 - - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
MEPAFCOE_01420 1e-132 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
MEPAFCOE_01421 7.89e-216 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
MEPAFCOE_01422 1.06e-235 - - - K - - - Transcriptional regulator
MEPAFCOE_01423 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MEPAFCOE_01424 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MEPAFCOE_01425 1.83e-136 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MEPAFCOE_01426 2.87e-213 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
MEPAFCOE_01427 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MEPAFCOE_01428 1.68e-121 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MEPAFCOE_01429 5.87e-228 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family. XerC subfamily
MEPAFCOE_01430 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MEPAFCOE_01431 2.53e-210 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
MEPAFCOE_01432 5.64e-172 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MEPAFCOE_01433 6.95e-203 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MEPAFCOE_01435 9.5e-98 abiGI - - K - - - Psort location Cytoplasmic, score
MEPAFCOE_01438 6.13e-165 - - - - - - - -
MEPAFCOE_01439 6.56e-48 yozE - - S - - - Belongs to the UPF0346 family
MEPAFCOE_01440 9.91e-137 ypmS - - S - - - Uncharacterized protein conserved in bacteria (DUF2140)
MEPAFCOE_01441 1.47e-214 XK27_03630 - - E - - - GDSL-like Lipase/Acylhydrolase
MEPAFCOE_01442 1.23e-190 WQ51_01275 - - S - - - EDD domain protein, DegV family
MEPAFCOE_01443 1.06e-147 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
MEPAFCOE_01444 6.78e-136 - - - K - - - acetyltransferase
MEPAFCOE_01445 1.68e-225 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
MEPAFCOE_01446 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
MEPAFCOE_01447 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
MEPAFCOE_01448 2.61e-154 pgm3 - - G - - - phosphoglycerate mutase
MEPAFCOE_01449 3.27e-229 oppF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MEPAFCOE_01450 1.24e-259 oppD - - P ko:K02031,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MEPAFCOE_01451 1.11e-238 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MEPAFCOE_01452 7.11e-203 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MEPAFCOE_01453 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MEPAFCOE_01454 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MEPAFCOE_01455 2.8e-295 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MEPAFCOE_01456 4.59e-140 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MEPAFCOE_01457 1.5e-142 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MEPAFCOE_01458 1.29e-194 glnH - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
MEPAFCOE_01459 8.35e-175 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MEPAFCOE_01460 4.22e-216 - - - - - - - -
MEPAFCOE_01461 4.52e-47 - 3.2.1.14 GH18 - ko:K01183 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 -
MEPAFCOE_01462 2.18e-19 - - - - - - - -
MEPAFCOE_01463 1.2e-234 - - - - - - - -
MEPAFCOE_01465 5.57e-129 yobS - - K - - - Bacterial regulatory proteins, tetR family
MEPAFCOE_01466 2.3e-96 - - - K - - - helix_turn_helix, mercury resistance
MEPAFCOE_01467 1.06e-100 yphH - - S - - - Cupin domain
MEPAFCOE_01468 3.88e-71 yphJ 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 decarboxylase
MEPAFCOE_01469 1.1e-257 - - - G - - - Glycosyl hydrolases family 8
MEPAFCOE_01470 2.25e-214 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 hydrolase, family 25
MEPAFCOE_01471 1.11e-192 - - - S - - - Zinc-dependent metalloprotease
MEPAFCOE_01472 2.12e-136 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
MEPAFCOE_01473 1.58e-263 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
MEPAFCOE_01474 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 Putative exonuclease SbcCD, C subunit
MEPAFCOE_01475 3.06e-238 pva2 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
MEPAFCOE_01476 0.0 - 3.2.1.21, 3.2.1.52 GH3 G ko:K01207,ko:K05349 ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501 ko00000,ko00001,ko00002,ko01000 hydrolase, family 3
MEPAFCOE_01478 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MEPAFCOE_01479 1.49e-125 tag2 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
MEPAFCOE_01480 4.65e-187 - - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
MEPAFCOE_01481 2.44e-244 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MEPAFCOE_01482 5.79e-147 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MEPAFCOE_01483 4.13e-43 - - - S ko:K21449 - ko00000,ko02000 Domain of unknown function (DUF4430)
MEPAFCOE_01484 0.0 gshR3 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
MEPAFCOE_01485 5.57e-115 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
MEPAFCOE_01486 1.17e-175 azlC - - E - - - AzlC protein
MEPAFCOE_01487 1.3e-71 - - - S - - - branched-chain amino acid
MEPAFCOE_01488 1.14e-302 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
MEPAFCOE_01489 4.7e-177 - - - - - - - -
MEPAFCOE_01490 1.31e-271 xylR - - GK - - - ROK family
MEPAFCOE_01491 6.11e-238 ydbI - - K - - - AI-2E family transporter
MEPAFCOE_01492 0.0 - - - M - - - domain protein
MEPAFCOE_01493 3.05e-169 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MEPAFCOE_01494 1.65e-108 yafP - - K ko:K03830 - ko00000,ko01000 Acetyltransferase (GNAT) domain
MEPAFCOE_01495 4.28e-53 - - - - - - - -
MEPAFCOE_01496 1.26e-51 - - - S - - - Protein of unknown function (DUF3781)
MEPAFCOE_01497 2.31e-283 - - - U - - - Belongs to the major facilitator superfamily
MEPAFCOE_01498 1.4e-213 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
MEPAFCOE_01499 1.58e-138 - 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 DJ-1/PfpI family
MEPAFCOE_01500 9.55e-266 - - - - - - - -
MEPAFCOE_01502 0.0 arcT - - E - - - Dipeptidase
MEPAFCOE_01503 0.0 arcD - - S - - - C4-dicarboxylate anaerobic carrier
MEPAFCOE_01504 4.64e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
MEPAFCOE_01505 1.43e-75 yloU - - S - - - Asp23 family, cell envelope-related function
MEPAFCOE_01506 0.0 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
MEPAFCOE_01507 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MEPAFCOE_01508 2.73e-241 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MEPAFCOE_01509 3.98e-49 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
MEPAFCOE_01510 5.47e-167 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MEPAFCOE_01511 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
MEPAFCOE_01512 1.64e-249 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MEPAFCOE_01513 8.53e-76 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MEPAFCOE_01514 3.49e-280 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MEPAFCOE_01515 0.0 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
MEPAFCOE_01516 1.09e-272 - - - S - - - associated with various cellular activities
MEPAFCOE_01517 0.0 - - - S - - - Putative metallopeptidase domain
MEPAFCOE_01518 7.31e-65 - - - - - - - -
MEPAFCOE_01519 3.48e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
MEPAFCOE_01520 2.63e-53 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
MEPAFCOE_01521 3.58e-119 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MEPAFCOE_01522 9.06e-183 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
MEPAFCOE_01523 2.13e-76 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MEPAFCOE_01524 0.0 - 3.4.19.1 - E ko:K01303 - ko00000,ko01000,ko01002 Prolyl oligopeptidase family
MEPAFCOE_01525 1.42e-218 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MEPAFCOE_01526 7.46e-59 - - - - - - - -
MEPAFCOE_01527 3.64e-86 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MEPAFCOE_01528 0.0 nhaP2 - - P ko:K03316 - ko00000 Sodium proton antiporter
MEPAFCOE_01529 0.0 yfkN 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
MEPAFCOE_01530 0.0 astA 2.8.2.22 - M ko:K01023 - ko00000,ko01000 Arylsulfotransferase Ig-like domain
MEPAFCOE_01531 1.55e-151 - - - S - - - Protein of unknown function (DUF1275)
MEPAFCOE_01532 1.44e-199 rihA - - F ko:K01250 - ko00000,ko01000 Inosine-uridine preferring nucleoside hydrolase
MEPAFCOE_01534 1.71e-239 nupC - - F ko:K11535 - ko00000,ko02000 Na+ dependent nucleoside transporter C-terminus
MEPAFCOE_01535 1.78e-188 - 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
MEPAFCOE_01536 3.19e-94 - - - S - - - Membrane
MEPAFCOE_01537 1.25e-143 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
MEPAFCOE_01538 5.77e-156 psuK 2.7.1.83 - G ko:K16328 ko00240,map00240 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
MEPAFCOE_01539 1.08e-139 psuK 2.7.1.83 - GK ko:K16328 ko00240,map00240 ko00000,ko00001,ko01000 Winged helix-turn-helix DNA-binding
MEPAFCOE_01541 7.41e-229 - - - K ko:K02529,ko:K03435 - ko00000,ko03000 helix_turn _helix lactose operon repressor
MEPAFCOE_01542 1.48e-69 - - - S - - - Pentapeptide repeats (8 copies)
MEPAFCOE_01543 4.43e-129 ywlG - - S - - - Belongs to the UPF0340 family
MEPAFCOE_01544 5.54e-111 hmpT - - S - - - ECF-type riboflavin transporter, S component
MEPAFCOE_01545 3.8e-180 thiD 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
MEPAFCOE_01546 0.0 norG_2 - - K - - - Aminotransferase class I and II
MEPAFCOE_01547 9.85e-283 ywtF_2 - - K - - - Cell envelope-related transcriptional attenuator domain
MEPAFCOE_01548 6.08e-179 - - - P ko:K02049 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
MEPAFCOE_01549 4.71e-189 - - - P ko:K02050 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MEPAFCOE_01550 6.03e-204 - - - P ko:K02050 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MEPAFCOE_01551 3.11e-290 rodA - - D ko:K05837 - ko00000,ko03036 Cell cycle protein
MEPAFCOE_01552 9.6e-27 - - - - - - - -
MEPAFCOE_01553 1.31e-76 - - - - - - - -
MEPAFCOE_01555 1.23e-92 - 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase
MEPAFCOE_01556 6.12e-184 - - - S - - - Membrane
MEPAFCOE_01557 8.46e-239 tdh 1.1.1.14 - C ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Zinc-binding dehydrogenase
MEPAFCOE_01558 1.81e-221 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
MEPAFCOE_01559 3.42e-97 - - - - - - - -
MEPAFCOE_01560 9.54e-262 gldA 1.1.1.6 - C ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 ko00000,ko00001,ko01000 dehydrogenase
MEPAFCOE_01561 8.43e-65 ykkC - - P ko:K18924 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
MEPAFCOE_01562 3.77e-68 ykkD - - P ko:K18925 - ko00000,ko00002,ko02000 Multidrug resistance protein
MEPAFCOE_01563 1.2e-128 yokL3 - - J - - - Acetyltransferase (GNAT) domain
MEPAFCOE_01564 8.63e-188 - - - G - - - Belongs to the phosphoglycerate mutase family
MEPAFCOE_01566 0.0 treP 2.4.1.64 GH65 G ko:K05342 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
MEPAFCOE_01567 4.28e-252 - - - I - - - alpha/beta hydrolase fold
MEPAFCOE_01568 0.0 xylP2 - - G - - - symporter
MEPAFCOE_01569 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MEPAFCOE_01570 4.9e-105 - - - - - - - -
MEPAFCOE_01572 7.38e-228 cytR - - K ko:K02529,ko:K03604 - ko00000,ko03000 Transcriptional regulator, LacI family
MEPAFCOE_01573 0.0 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
MEPAFCOE_01574 0.0 - 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
MEPAFCOE_01575 2.22e-146 - - - - - - - -
MEPAFCOE_01576 1.19e-97 - - - K - - - helix_turn_helix, mercury resistance
MEPAFCOE_01577 4.33e-69 - - - K - - - Transcriptional regulator
MEPAFCOE_01578 1.3e-35 - - - C - - - alcohol dehydrogenase
MEPAFCOE_01579 6.23e-94 - - - C - - - alcohol dehydrogenase
MEPAFCOE_01580 4.1e-93 - 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Bacterial transferase hexapeptide (six repeats)
MEPAFCOE_01581 5.6e-125 - - - C - - - Oxidoreductase
MEPAFCOE_01582 1.06e-107 - - - C - - - Oxidoreductase
MEPAFCOE_01584 1.83e-84 - - - K - - - Transcriptional regulator, HxlR family
MEPAFCOE_01585 1.04e-219 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MEPAFCOE_01586 1.57e-281 dhaT 1.1.1.202 - C ko:K00086 ko00561,ko00640,map00561,map00640 ko00000,ko00001,ko01000 Dehydrogenase
MEPAFCOE_01587 7.8e-155 - 3.8.1.2 - S ko:K01560 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
MEPAFCOE_01588 2.14e-141 - - - S ko:K15770 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 GyrI-like small molecule binding domain
MEPAFCOE_01589 3.12e-286 - - - U - - - Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MEPAFCOE_01590 1.89e-157 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MEPAFCOE_01591 5.38e-231 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
MEPAFCOE_01592 1.98e-112 - - - K - - - Bacterial regulatory proteins, tetR family
MEPAFCOE_01593 1.66e-270 - - - EGP - - - Major Facilitator Superfamily
MEPAFCOE_01594 1.24e-83 - - - G - - - Domain of unknown function (DUF386)
MEPAFCOE_01595 7.08e-275 - - - G - - - Sugar (and other) transporter
MEPAFCOE_01596 5.25e-106 - - - G - - - Domain of unknown function (DUF386)
MEPAFCOE_01597 1.88e-165 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
MEPAFCOE_01598 9.44e-185 sga 5.1.3.22 - G ko:K03079 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Xylose isomerase-like TIM barrel
MEPAFCOE_01599 4.39e-295 - 2.7.1.53 - G ko:K00880 ko00040,ko00053,map00040,map00053 ko00000,ko00001,ko01000 Xylulose kinase
MEPAFCOE_01600 1.79e-209 - - - - - - - -
MEPAFCOE_01601 4.54e-199 gyaR 1.1.1.26, 1.1.1.399, 1.1.1.95 - CH ko:K00015,ko:K00058 ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MEPAFCOE_01602 5.15e-179 - - - K ko:K02525 - ko00000,ko03000 helix_turn _helix lactose operon repressor
MEPAFCOE_01603 3.18e-140 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MEPAFCOE_01604 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
MEPAFCOE_01605 1.01e-116 - - - K - - - Transcriptional regulator, MarR family
MEPAFCOE_01606 3.35e-156 - - - S ko:K07090 - ko00000 membrane transporter protein
MEPAFCOE_01607 3.12e-145 - - - T - - - Tyrosine phosphatase family
MEPAFCOE_01608 4.33e-159 - - - - - - - -
MEPAFCOE_01609 2.77e-159 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
MEPAFCOE_01610 1.52e-81 lexA - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator, GntR family
MEPAFCOE_01611 1.27e-222 - 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
MEPAFCOE_01612 9.4e-110 gpo 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
MEPAFCOE_01613 7.25e-162 - - - S - - - haloacid dehalogenase-like hydrolase
MEPAFCOE_01614 1.03e-266 - - - EGP ko:K02030,ko:K07552 - ko00000,ko00002,ko02000 Drug resistance transporter Bcr CflA subfamily
MEPAFCOE_01615 5.02e-187 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
MEPAFCOE_01616 4.2e-201 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
MEPAFCOE_01617 1.71e-146 - - - - - - - -
MEPAFCOE_01619 1.14e-170 - - - S - - - KR domain
MEPAFCOE_01620 1.8e-87 - - - K - - - HxlR-like helix-turn-helix
MEPAFCOE_01621 5.5e-83 asp2 - - S - - - Asp23 family, cell envelope-related function
MEPAFCOE_01622 4.16e-93 - - - S - - - Asp23 family, cell envelope-related function
MEPAFCOE_01623 1.02e-34 - - - - - - - -
MEPAFCOE_01624 1.23e-119 - - - - - - - -
MEPAFCOE_01625 4.98e-44 - - - S - - - Transglycosylase associated protein
MEPAFCOE_01626 8.01e-202 - - - - - - - -
MEPAFCOE_01627 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
MEPAFCOE_01628 1.2e-113 - - - U - - - Major Facilitator Superfamily
MEPAFCOE_01629 2.17e-127 lemA - - S ko:K03744 - ko00000 LemA family
MEPAFCOE_01630 1.88e-197 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
MEPAFCOE_01631 7.79e-192 - - - - - - - -
MEPAFCOE_01632 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MEPAFCOE_01633 0.0 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MEPAFCOE_01634 1.67e-271 - - - S - - - nuclear-transcribed mRNA catabolic process, no-go decay
MEPAFCOE_01635 9.61e-84 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MEPAFCOE_01636 1.74e-274 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MEPAFCOE_01638 1.45e-80 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
MEPAFCOE_01639 7.47e-148 - - - S - - - (CBS) domain
MEPAFCOE_01641 0.0 - - - S - - - Putative peptidoglycan binding domain
MEPAFCOE_01642 5.62e-225 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
MEPAFCOE_01643 1.05e-131 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MEPAFCOE_01644 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MEPAFCOE_01645 0.0 yabM - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
MEPAFCOE_01646 7.09e-53 yabO - - J - - - S4 domain protein
MEPAFCOE_01647 9.05e-58 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
MEPAFCOE_01649 3.39e-34 azoR - - C ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MEPAFCOE_01650 5.04e-312 glpT - - G ko:K02445 - ko00000,ko02000 Major Facilitator Superfamily
MEPAFCOE_01651 3.25e-273 yttB - - EGP - - - Major Facilitator
MEPAFCOE_01652 3.88e-149 - - - - - - - -
MEPAFCOE_01653 1.85e-204 - 1.1.1.65 - C ko:K05275 ko00750,ko01100,ko01120,map00750,map01100,map01120 ko00000,ko00001,ko01000 Aldo keto reductase
MEPAFCOE_01654 1.65e-204 - 2.3.1.81 - V ko:K00662 - ko00000,ko01000,ko01504 Aminoglycoside 3-N-acetyltransferase
MEPAFCOE_01655 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MEPAFCOE_01656 3.49e-102 - - - S ko:K02348 - ko00000 Gnat family
MEPAFCOE_01657 4.64e-96 - - - K - - - Transcriptional regulator
MEPAFCOE_01658 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MEPAFCOE_01661 5.81e-63 - - - K - - - Helix-turn-helix domain
MEPAFCOE_01663 3.28e-61 - - - - - - - -
MEPAFCOE_01664 5.26e-148 - - - GM - - - NAD(P)H-binding
MEPAFCOE_01665 1.84e-80 - - - - - - - -
MEPAFCOE_01666 5.01e-138 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Peroxiredoxin
MEPAFCOE_01667 3.25e-291 gltT - - U ko:K03309,ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MEPAFCOE_01668 9e-74 - - - S - - - Domain of unknown function (DUF3899)
MEPAFCOE_01669 2.8e-229 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MEPAFCOE_01670 6.29e-307 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MEPAFCOE_01671 1.69e-184 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
MEPAFCOE_01674 2.09e-173 znuB - - U ko:K02075,ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
MEPAFCOE_01675 4.16e-168 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
MEPAFCOE_01676 4.59e-219 psaA - - P ko:K02077,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
MEPAFCOE_01677 1.94e-206 - - - S ko:K06889 - ko00000 Prolyl oligopeptidase family
MEPAFCOE_01679 2.09e-07 - - - - - - - -
MEPAFCOE_01680 5.74e-211 ypbG 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
MEPAFCOE_01681 1.78e-124 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MEPAFCOE_01682 1.07e-200 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MEPAFCOE_01683 2.28e-272 xylR - - GK - - - ROK family
MEPAFCOE_01684 0.0 xylP - - G ko:K03292 - ko00000 MFS/sugar transport protein
MEPAFCOE_01685 0.0 yicI 3.2.1.177 GH31 G ko:K01811 - ko00000,ko01000 Belongs to the glycosyl hydrolase 31 family
MEPAFCOE_01686 2.84e-116 ung2 - - L - - - Uracil-DNA glycosylase
MEPAFCOE_01687 8.65e-144 aqpZ - - U ko:K06188 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
MEPAFCOE_01688 2.25e-76 - - - S - - - Domain of unknown function (DU1801)
MEPAFCOE_01689 0.0 epsA - - I - - - PAP2 superfamily
MEPAFCOE_01690 9.53e-93 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
MEPAFCOE_01691 9.15e-207 - - - K - - - LysR substrate binding domain
MEPAFCOE_01692 0.0 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
MEPAFCOE_01693 1.87e-126 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
MEPAFCOE_01694 2.34e-93 - - - - - - - -
MEPAFCOE_01695 3.16e-204 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type cobalt transport system permease component CbiQ and related transporters
MEPAFCOE_01696 0.0 - - - S ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
MEPAFCOE_01697 1.15e-146 - - - S ko:K16927 - ko00000,ko00002,ko02000 ECF-type riboflavin transporter, S component
MEPAFCOE_01698 1.43e-229 - - - U - - - FFAT motif binding
MEPAFCOE_01699 1.35e-122 - - - S - - - Domain of unknown function (DUF4430)
MEPAFCOE_01700 1.33e-34 - - - K - - - helix_turn_helix, arabinose operon control protein
MEPAFCOE_01701 3.04e-53 pduN - - CQ ko:K04028 - ko00000 Ethanolamine utilisation protein EutN/carboxysome
MEPAFCOE_01702 6.81e-172 namA - - C - - - Oxidoreductase
MEPAFCOE_01703 1.57e-262 - - - EGP - - - Major Facilitator
MEPAFCOE_01705 7.21e-08 - - - L - - - Transposase and inactivated derivatives, IS30 family
MEPAFCOE_01706 0.0 - 1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31 - Q ko:K10027 ko00906,ko01100,ko01110,map00906,map01100,map01110 ko00000,ko00001,ko01000 Flavin containing amine oxidoreductase
MEPAFCOE_01707 1.36e-208 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Squalene/phytoene synthase
MEPAFCOE_01709 2.15e-77 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
MEPAFCOE_01710 3.68e-104 - - - L - - - Transposase DDE domain
MEPAFCOE_01711 3.05e-186 - - - L - - - 4.5 Transposon and IS
MEPAFCOE_01712 2.71e-33 - - - L ko:K07483 - ko00000 Transposase
MEPAFCOE_01713 6.84e-233 - - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
MEPAFCOE_01714 2.38e-153 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 COG1136 ABC-type antimicrobial peptide transport system, ATPase component
MEPAFCOE_01715 3.15e-78 - - - S - - - Bacterial toxin of type II toxin-antitoxin system, YafQ
MEPAFCOE_01716 3.88e-60 - - - D ko:K19159 - ko00000,ko02048 Antitoxin component of a toxin-antitoxin (TA) module
MEPAFCOE_01717 4.4e-138 - - - L - - - Integrase
MEPAFCOE_01718 2.08e-60 - - - S - - - Phage derived protein Gp49-like (DUF891)
MEPAFCOE_01719 3.03e-49 - - - K - - - sequence-specific DNA binding
MEPAFCOE_01720 3.02e-68 - - - S - - - Bacterial mobilisation protein (MobC)
MEPAFCOE_01721 4.81e-232 - - - U - - - Relaxase/Mobilisation nuclease domain
MEPAFCOE_01722 1.91e-91 - - - - - - - -
MEPAFCOE_01723 3.06e-35 - - - L ko:K07483 - ko00000 Homeodomain-like domain
MEPAFCOE_01724 3.7e-164 - - - L ko:K07498 - ko00000 Transposase IS66 family
MEPAFCOE_01725 9.84e-58 - - - L - - - Transposase and inactivated derivatives, IS30 family
MEPAFCOE_01726 3.9e-109 - - - L - - - Belongs to the 'phage' integrase family
MEPAFCOE_01727 3.11e-48 - - - T - - - PemK-like, MazF-like toxin of type II toxin-antitoxin system
MEPAFCOE_01730 9.48e-64 - - - E - - - IrrE N-terminal-like domain
MEPAFCOE_01731 1.63e-48 - - - K - - - Helix-turn-helix XRE-family like proteins
MEPAFCOE_01732 2.13e-10 - - - K - - - sequence-specific DNA binding
MEPAFCOE_01744 1.13e-83 - - - L ko:K07455 - ko00000,ko03400 RecT family
MEPAFCOE_01745 3.38e-105 pi112 - - L - - - PDDEXK-like domain of unknown function (DUF3799)
MEPAFCOE_01747 2.94e-68 - - - K ko:K07741 - ko00000 AntA/AntB antirepressor
MEPAFCOE_01748 1.55e-54 - - - S - - - Endodeoxyribonuclease RusA
MEPAFCOE_01751 1.99e-42 - - - - - - - -
MEPAFCOE_01752 2.96e-72 - - - - - - - -
MEPAFCOE_01754 1.58e-227 - - - S - - - Baseplate J-like protein
MEPAFCOE_01755 2.95e-95 - - - - - - - -
MEPAFCOE_01758 2.1e-65 - - - N ko:K18843 - ko00000,ko02048 PFAM Uncharacterised protein family UPF0150
MEPAFCOE_01759 5.15e-91 - - - K - - - LytTr DNA-binding domain
MEPAFCOE_01760 1.35e-102 - - - S - - - Protein of unknown function (DUF3021)
MEPAFCOE_01761 6.43e-117 entB - - Q - - - Isochorismatase family
MEPAFCOE_01762 8.49e-66 - - - S - - - MazG nucleotide pyrophosphohydrolase domain
MEPAFCOE_01763 6.62e-111 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
MEPAFCOE_01764 6.51e-176 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MEPAFCOE_01765 4.26e-171 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
MEPAFCOE_01766 6.61e-181 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 alpha subunit
MEPAFCOE_01767 3.71e-198 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MEPAFCOE_01768 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
MEPAFCOE_01769 5.31e-90 fabZ2 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
MEPAFCOE_01770 3.4e-93 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MEPAFCOE_01771 5.36e-289 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MEPAFCOE_01772 2.74e-157 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
MEPAFCOE_01773 4.92e-212 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
MEPAFCOE_01774 1.84e-49 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
MEPAFCOE_01775 3.29e-233 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MEPAFCOE_01776 2.5e-104 - - - K - - - Transcriptional regulator
MEPAFCOE_01777 9.21e-99 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MEPAFCOE_01778 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
MEPAFCOE_01779 0.0 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MEPAFCOE_01780 1.93e-214 - - - - - - - -
MEPAFCOE_01781 1.44e-122 - - - S - - - Protein of unknown function (DUF1097)
MEPAFCOE_01782 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
MEPAFCOE_01783 6.68e-199 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MEPAFCOE_01784 2.19e-75 yuxO - - Q - - - Thioesterase superfamily
MEPAFCOE_01785 1.71e-110 - - - S - - - Protein of unknown function (DUF2798)
MEPAFCOE_01786 1.37e-128 - - - S ko:K09962 - ko00000 Nucleotidyltransferase
MEPAFCOE_01787 4.79e-126 - - - - - - - -
MEPAFCOE_01788 2.4e-71 - - - S - - - protein encoded in hypervariable junctions of pilus gene clusters
MEPAFCOE_01789 8.55e-186 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 prohibitin homologues
MEPAFCOE_01790 2.77e-290 - - - S ko:K01421 - ko00000 ABC-2 family transporter protein
MEPAFCOE_01791 7.48e-147 - - - K - - - Bacterial regulatory proteins, tetR family
MEPAFCOE_01792 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
MEPAFCOE_01793 6.62e-105 - - - S - - - GtrA-like protein
MEPAFCOE_01794 2.78e-168 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MEPAFCOE_01795 4.3e-106 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MEPAFCOE_01796 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MEPAFCOE_01797 6.58e-175 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Serine aminopeptidase, S33
MEPAFCOE_01798 1.06e-44 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
MEPAFCOE_01799 0.0 eriC - - P ko:K03281 - ko00000 chloride
MEPAFCOE_01801 1.89e-316 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MEPAFCOE_01802 5.46e-179 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MEPAFCOE_01803 7.88e-287 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
MEPAFCOE_01804 8.53e-245 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MEPAFCOE_01805 1.99e-237 cggR - - K ko:K05311 - ko00000,ko03000 Putative sugar-binding domain
MEPAFCOE_01807 2.33e-137 - - - S - - - ECF transporter, substrate-specific component
MEPAFCOE_01809 6.3e-161 - - - S - - - membrane
MEPAFCOE_01810 9.98e-35 - - - - - - - -
MEPAFCOE_01811 0.0 tagE2 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
MEPAFCOE_01812 0.0 tagE3 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
MEPAFCOE_01813 2.14e-19 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
MEPAFCOE_01814 4.34e-138 cutC - - P ko:K06201 - ko00000 Participates in the control of copper homeostasis
MEPAFCOE_01815 7.47e-262 XK27_05220 - - S - - - AI-2E family transporter
MEPAFCOE_01816 2.71e-199 rrmA 2.1.1.187 - H ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 Methyltransferase
MEPAFCOE_01817 1.72e-125 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MEPAFCOE_01818 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
MEPAFCOE_01819 4.92e-18 - - - S - - - Protein of unknown function (DUF4044)
MEPAFCOE_01820 1.24e-79 - - - S - - - Protein of unknown function (DUF3397)
MEPAFCOE_01821 2.68e-13 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
MEPAFCOE_01822 2.62e-294 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
MEPAFCOE_01823 1.38e-102 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
MEPAFCOE_01824 3.53e-226 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MEPAFCOE_01825 1.22e-79 ftsL - - D - - - Cell division protein FtsL
MEPAFCOE_01826 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
MEPAFCOE_01827 3.06e-236 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MEPAFCOE_01828 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MEPAFCOE_01829 1.69e-256 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MEPAFCOE_01830 8.63e-194 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MEPAFCOE_01831 7.1e-309 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MEPAFCOE_01832 1.48e-287 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MEPAFCOE_01833 1.49e-97 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MEPAFCOE_01834 1.98e-54 ylmG - - S ko:K02221 - ko00000,ko02044 YGGT family
MEPAFCOE_01835 2.81e-184 ylmH - - S - - - S4 domain protein
MEPAFCOE_01836 3.17e-133 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
MEPAFCOE_01837 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MEPAFCOE_01838 4.08e-47 cspB - - K ko:K03704 - ko00000,ko03000 Cold shock protein
MEPAFCOE_01839 2.04e-122 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
MEPAFCOE_01840 1.93e-47 - - - - - - - -
MEPAFCOE_01841 3.68e-161 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MEPAFCOE_01842 8.2e-288 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
MEPAFCOE_01843 1.79e-77 XK27_04120 - - S - - - Putative amino acid metabolism
MEPAFCOE_01845 4.16e-283 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MEPAFCOE_01846 2.23e-156 pgm6 - - G - - - phosphoglycerate mutase
MEPAFCOE_01847 5.63e-154 - - - S - - - repeat protein
MEPAFCOE_01848 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MEPAFCOE_01849 1.81e-226 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MEPAFCOE_01850 3.68e-161 - - - S - - - Protein of unknown function (DUF1275)
MEPAFCOE_01851 6.33e-157 yckA - - E ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MEPAFCOE_01852 9.88e-206 yckB - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
MEPAFCOE_01853 0.0 nylA 3.5.1.4 - J ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 ko00000,ko00001,ko01000 Belongs to the amidase family
MEPAFCOE_01854 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MEPAFCOE_01855 6.58e-200 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MEPAFCOE_01856 2.25e-241 yghZ - - C ko:K19265 - ko00000,ko01000 Aldo keto reductase family protein
MEPAFCOE_01857 8.04e-237 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
MEPAFCOE_01858 1.45e-205 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MEPAFCOE_01859 0.0 tkt2 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MEPAFCOE_01860 1e-216 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 NlpC/P60 family
MEPAFCOE_01861 6.42e-217 ypuA - - S - - - Protein of unknown function (DUF1002)
MEPAFCOE_01862 1.36e-201 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
MEPAFCOE_01863 6.66e-39 - - - - - - - -
MEPAFCOE_01864 1.35e-237 - - - I - - - Diacylglycerol kinase catalytic
MEPAFCOE_01865 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MEPAFCOE_01866 9.82e-45 ykzG - - S - - - Belongs to the UPF0356 family
MEPAFCOE_01867 9.18e-105 - - - - - - - -
MEPAFCOE_01868 9.7e-133 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MEPAFCOE_01869 4.77e-271 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
MEPAFCOE_01870 1.15e-232 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Transketolase, C-terminal domain protein
MEPAFCOE_01871 7.45e-282 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MEPAFCOE_01872 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
MEPAFCOE_01873 1.16e-209 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 L-malate dehydrogenase activity
MEPAFCOE_01874 2.07e-60 yktA - - S - - - Belongs to the UPF0223 family
MEPAFCOE_01875 7.71e-184 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the inositol monophosphatase superfamily
MEPAFCOE_01876 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
MEPAFCOE_01877 1.04e-267 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
MEPAFCOE_01878 1.33e-57 ylbG - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
MEPAFCOE_01879 2.66e-126 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
MEPAFCOE_01880 4.98e-107 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MEPAFCOE_01881 1.54e-249 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
MEPAFCOE_01882 5.42e-117 - - - K - - - Transcriptional regulator PadR-like family
MEPAFCOE_01883 3.41e-107 - - - K - - - MerR family regulatory protein
MEPAFCOE_01884 6.48e-87 lytE - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family
MEPAFCOE_01885 3.26e-101 yyaT - - K ko:K02348 - ko00000 protein acetylation
MEPAFCOE_01886 6.66e-159 pgm3 - - G - - - phosphoglycerate mutase family
MEPAFCOE_01887 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MEPAFCOE_01888 5.02e-230 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
MEPAFCOE_01889 1.5e-180 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
MEPAFCOE_01890 1.65e-243 - - - S - - - Protease prsW family
MEPAFCOE_01891 6.11e-229 iunH1 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 nucleoside hydrolase
MEPAFCOE_01892 6.95e-10 - - - - - - - -
MEPAFCOE_01893 1.75e-129 - - - - - - - -
MEPAFCOE_01894 7.18e-193 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
MEPAFCOE_01895 6.68e-198 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
MEPAFCOE_01896 4.73e-303 - - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MEPAFCOE_01897 4.01e-185 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2087)
MEPAFCOE_01898 4.02e-244 - - - L - - - Psort location Cytoplasmic, score
MEPAFCOE_01899 0.0 traA - - L - - - MobA/MobL family
MEPAFCOE_01900 2.31e-35 - - - - - - - -
MEPAFCOE_01901 1.72e-54 - - - - - - - -
MEPAFCOE_01902 1.29e-49 - - - S - - - protein conserved in bacteria
MEPAFCOE_01903 1.23e-35 - - - - - - - -
MEPAFCOE_01904 1.26e-136 repA - - S - - - Replication initiator protein A
MEPAFCOE_01905 4.07e-196 - - - L ko:K07482 - ko00000 Integrase core domain
MEPAFCOE_01906 2.35e-28 repA - - S - - - Replication initiator protein A
MEPAFCOE_01907 0.0 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
MEPAFCOE_01909 6.13e-127 soj - - D - - - CobQ CobB MinD ParA nucleotide binding domain protein
MEPAFCOE_01911 3.44e-67 - - - S - - - Domain of unknown function (DUF4355)
MEPAFCOE_01912 3.62e-22 ytgB - - S - - - Transglycosylase associated protein
MEPAFCOE_01913 1.14e-168 - - - S - - - Phage Mu protein F like protein
MEPAFCOE_01914 0.0 mdr - - EGP - - - Major Facilitator
MEPAFCOE_01915 1.39e-74 XK27_08430 - - S - - - Staphylococcal protein of unknown function (DUF960)
MEPAFCOE_01916 1.03e-155 dgk2 - - F - - - Deoxynucleoside kinase
MEPAFCOE_01917 7.76e-185 - - - S - - - haloacid dehalogenase-like hydrolase
MEPAFCOE_01918 2.13e-152 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
MEPAFCOE_01919 0.0 trePP 2.4.1.216, 2.4.1.8 GH65 G ko:K00691,ko:K03731 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycosyl hydrolase family 65 central catalytic domain
MEPAFCOE_01920 5.62e-226 - 1.1.1.26 - CH ko:K00015 ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MEPAFCOE_01921 3.58e-51 - - - - - - - -
MEPAFCOE_01922 4.3e-158 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
MEPAFCOE_01923 2.39e-108 ohrR - - K - - - Transcriptional regulator
MEPAFCOE_01924 1.1e-116 - - - V - - - VanZ like family
MEPAFCOE_01925 4.08e-62 - - - - - - - -
MEPAFCOE_01928 0.0 - - - S - - - membrane
MEPAFCOE_01929 8.94e-75 yneR - - S - - - Belongs to the HesB IscA family
MEPAFCOE_01930 2.72e-92 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MEPAFCOE_01931 5.67e-155 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
MEPAFCOE_01932 7.58e-267 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MEPAFCOE_01933 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MEPAFCOE_01934 6.88e-257 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MEPAFCOE_01935 4.2e-88 yodB - - K - - - Transcriptional regulator, HxlR family
MEPAFCOE_01936 8.56e-119 - - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
MEPAFCOE_01937 2.91e-180 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MEPAFCOE_01938 2.66e-57 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
MEPAFCOE_01939 1.86e-193 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MEPAFCOE_01940 2.3e-96 - - - P - - - ArsC family
MEPAFCOE_01941 4.49e-185 lytE - - M - - - NlpC/P60 family
MEPAFCOE_01942 4.34e-201 - - - K - - - acetyltransferase
MEPAFCOE_01943 0.0 - - - E - - - dipeptidase activity
MEPAFCOE_01944 1.69e-88 - - - S ko:K07090 - ko00000 membrane transporter protein
MEPAFCOE_01945 1.2e-65 - - - S ko:K07090 - ko00000 membrane transporter protein
MEPAFCOE_01946 1.81e-159 - - - IQ - - - Enoyl-(Acyl carrier protein) reductase
MEPAFCOE_01947 7.05e-171 fabG1 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MEPAFCOE_01948 2.81e-197 - - - GM - - - NmrA-like family
MEPAFCOE_01949 8.91e-94 - - - K - - - Transcriptional regulator
MEPAFCOE_01950 0.0 tagB 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycerophosphotransferase
MEPAFCOE_01951 2.12e-93 - - - - - - - -
MEPAFCOE_01952 2.35e-94 - - - - - - - -
MEPAFCOE_01953 5.61e-82 ytcD - - K - - - Transcriptional regulator, HxlR family
MEPAFCOE_01954 7.08e-76 melB - - G - - - symporter
MEPAFCOE_01955 1.14e-224 araR - - K ko:K02103 - ko00000,ko03000 Transcriptional regulator
MEPAFCOE_01956 4.34e-186 - - - K - - - transcriptional regulator, ArsR family
MEPAFCOE_01957 1.43e-256 abf - - G - - - Belongs to the glycosyl hydrolase 43 family
MEPAFCOE_01958 1.31e-302 lacY - - G ko:K02532 - ko00000,ko02000 Oligosaccharide H symporter
MEPAFCOE_01959 0.0 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
MEPAFCOE_01960 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
MEPAFCOE_01961 1.56e-93 - - - K - - - Transcriptional regulator
MEPAFCOE_01962 2.53e-124 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
MEPAFCOE_01963 0.0 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
MEPAFCOE_01964 6.85e-297 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
MEPAFCOE_01965 4.94e-119 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
MEPAFCOE_01966 1.76e-176 yhfI - - S - - - Metallo-beta-lactamase superfamily
MEPAFCOE_01967 3.6e-92 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MEPAFCOE_01968 4.43e-165 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
MEPAFCOE_01969 9.61e-132 - - - T - - - EAL domain
MEPAFCOE_01970 2.74e-117 - - - - - - - -
MEPAFCOE_01971 1.98e-314 yijG - GT2 M ko:K11936 ko02026,map02026 ko00000,ko00001,ko01000,ko01003,ko02000 Glycosyl transferase
MEPAFCOE_01973 3.94e-133 ytqB - - J - - - Putative rRNA methylase
MEPAFCOE_01974 2.71e-150 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
MEPAFCOE_01975 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
MEPAFCOE_01977 2.86e-104 - - - L - - - Transposase and inactivated derivatives, IS30 family
MEPAFCOE_01978 2.77e-68 - - - L - - - transposition
MEPAFCOE_01979 1.17e-120 - 2.4.1.187 GT26 F ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
MEPAFCOE_01980 3.75e-221 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MEPAFCOE_01981 5.63e-84 - - - M - - - Glycosyltransferase Family 4
MEPAFCOE_01982 4.71e-62 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
MEPAFCOE_01983 7.59e-71 - - - M - - - -O-antigen
MEPAFCOE_01984 6.69e-100 cps2J - - S - - - Polysaccharide biosynthesis protein
MEPAFCOE_01985 3.08e-116 - - - S - - - Polysaccharide pyruvyl transferase
MEPAFCOE_01986 5.02e-84 - - - L - - - PFAM transposase, IS4 family protein
MEPAFCOE_01987 5.09e-202 is18 - - L - - - Integrase core domain
MEPAFCOE_01988 7.81e-114 - - - S - - - WxL domain surface cell wall-binding
MEPAFCOE_01989 0.0 - - - S - - - Leucine-rich repeat (LRR) protein
MEPAFCOE_01990 4.39e-303 - - - M - - - domain protein
MEPAFCOE_01991 0.0 - - - E ko:K03294 - ko00000 Amino Acid
MEPAFCOE_01992 1.44e-184 dhrS4 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Oxidoreductase, short chain dehydrogenase reductase family protein
MEPAFCOE_01993 1.98e-156 dedA - - S ko:K03975 - ko00000 SNARE-like domain protein
MEPAFCOE_01994 7.54e-115 pgpA 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Phosphatidylglycerophosphatase A
MEPAFCOE_01995 4.07e-144 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MEPAFCOE_01996 4.82e-94 yugI - - J ko:K07570,ko:K07571 - ko00000 general stress protein
MEPAFCOE_01997 2.12e-222 - - - - - - - -
MEPAFCOE_01999 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MEPAFCOE_02000 0.0 - 4.1.1.15, 4.1.2.27 - E ko:K01580,ko:K01634 ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940 ko00000,ko00001,ko00002,ko01000 Belongs to the group II decarboxylase family
MEPAFCOE_02001 6.36e-75 - - - E ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 amino acid
MEPAFCOE_02002 6.38e-258 - - - E ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 amino acid
MEPAFCOE_02003 1.31e-135 - - - K - - - Bacterial regulatory proteins, tetR family
MEPAFCOE_02004 5.62e-229 - - - C - - - nadph quinone reductase
MEPAFCOE_02005 1.55e-128 - - - K - - - Bacterial regulatory proteins, tetR family
MEPAFCOE_02008 8.89e-269 - - - E - - - Major Facilitator Superfamily
MEPAFCOE_02010 6.81e-83 - - - - - - - -
MEPAFCOE_02011 2.33e-57 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MEPAFCOE_02012 1.79e-71 - - - - - - - -
MEPAFCOE_02013 5.23e-229 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
MEPAFCOE_02014 8.59e-170 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MEPAFCOE_02015 1.6e-79 - - - - - - - -
MEPAFCOE_02016 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MEPAFCOE_02017 1.21e-98 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MEPAFCOE_02018 7.47e-148 - - - S - - - HAD-hyrolase-like
MEPAFCOE_02019 5.83e-208 - - - G - - - Fructosamine kinase
MEPAFCOE_02020 2.24e-202 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 N-acetylmuramoyl-L-alanine amidase
MEPAFCOE_02021 2.71e-125 - - - - - - - -
MEPAFCOE_02022 1.89e-312 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
MEPAFCOE_02023 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
MEPAFCOE_02024 3.57e-125 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MEPAFCOE_02025 1.65e-208 yitT - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
MEPAFCOE_02026 9.98e-262 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MEPAFCOE_02027 1.84e-194 tagG - - U ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
MEPAFCOE_02028 3.08e-308 - 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycerophosphotransferase
MEPAFCOE_02029 6.04e-220 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MEPAFCOE_02030 1.69e-193 yqfL 2.7.11.33, 2.7.4.28 - F ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MEPAFCOE_02031 2.21e-30 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
MEPAFCOE_02032 4.75e-245 qor 1.1.1.1, 1.6.5.5 - C ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
MEPAFCOE_02033 1.27e-79 ydeP - - K - - - Transcriptional regulator, HxlR family
MEPAFCOE_02034 1.72e-94 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
MEPAFCOE_02035 2.8e-230 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
MEPAFCOE_02036 1.22e-112 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MEPAFCOE_02037 2.74e-81 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
MEPAFCOE_02038 1.27e-217 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MEPAFCOE_02039 3.06e-193 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
MEPAFCOE_02040 7.13e-227 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
MEPAFCOE_02041 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
MEPAFCOE_02042 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MEPAFCOE_02043 9.66e-252 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MEPAFCOE_02044 1.11e-111 - - - K - - - Transcriptional regulator
MEPAFCOE_02045 0.0 ydgH - - S ko:K06994 - ko00000 MMPL family
MEPAFCOE_02046 1.14e-162 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
MEPAFCOE_02047 1.52e-197 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MEPAFCOE_02048 8.41e-300 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
MEPAFCOE_02049 0.0 clpB - - O ko:K03695 ko04213,map04213 ko00000,ko00001,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MEPAFCOE_02050 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
MEPAFCOE_02051 2.27e-161 tal2 2.2.1.2 - H ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase/Fructose-6-phosphate aldolase
MEPAFCOE_02052 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
MEPAFCOE_02053 3.1e-214 yitL - - S ko:K00243 - ko00000 S1 domain
MEPAFCOE_02054 1.79e-211 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
MEPAFCOE_02055 7.96e-94 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MEPAFCOE_02056 4.42e-170 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MEPAFCOE_02057 1.7e-133 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MEPAFCOE_02058 2.58e-166 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
MEPAFCOE_02059 4.5e-121 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MEPAFCOE_02060 5.95e-240 - - - S - - - Helix-turn-helix domain
MEPAFCOE_02061 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
MEPAFCOE_02062 4.61e-63 - - - M - - - Lysin motif
MEPAFCOE_02063 9.33e-153 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
MEPAFCOE_02064 2.29e-278 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
MEPAFCOE_02065 1.34e-314 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
MEPAFCOE_02066 1.87e-53 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MEPAFCOE_02067 4.5e-298 XK27_05225 - - S - - - Tetratricopeptide repeat protein
MEPAFCOE_02068 2.98e-217 ypjC - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
MEPAFCOE_02069 5.97e-285 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MEPAFCOE_02070 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 ABC transporter, ATP-binding protein
MEPAFCOE_02071 3.88e-240 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MEPAFCOE_02072 8.6e-118 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MEPAFCOE_02073 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
MEPAFCOE_02074 5.33e-30 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
MEPAFCOE_02075 1.09e-118 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MEPAFCOE_02076 3.64e-150 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Peptidase, S54 family
MEPAFCOE_02077 9.85e-49 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
MEPAFCOE_02078 3.99e-232 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
MEPAFCOE_02079 1.11e-92 yqhL - - P - - - Rhodanese-like protein
MEPAFCOE_02080 1.23e-32 WQ51_02665 - - S - - - Protein of unknown function (DUF3042)
MEPAFCOE_02081 2.31e-179 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 phosphodiesterase
MEPAFCOE_02082 7.04e-218 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MEPAFCOE_02083 7.74e-86 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 Transcriptional regulator
MEPAFCOE_02084 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
MEPAFCOE_02087 5.12e-71 - - - S ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Glycine cleavage H-protein
MEPAFCOE_02088 6.49e-212 yjbO 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
MEPAFCOE_02089 2.05e-181 yejC - - S - - - Protein of unknown function (DUF1003)
MEPAFCOE_02090 1.26e-137 - - - K ko:K06977 - ko00000 acetyltransferase
MEPAFCOE_02091 1.88e-111 nimA - - S ko:K07005 - ko00000 resistance protein
MEPAFCOE_02092 4.05e-07 - - - L ko:K07483,ko:K09936 ko02024,map02024 ko00000,ko00001,ko02000 Helix-turn-helix domain
MEPAFCOE_02093 3.42e-132 - - - L - - - PFAM Integrase catalytic region
MEPAFCOE_02094 1.15e-115 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
MEPAFCOE_02095 5.81e-92 - - - - - - - -
MEPAFCOE_02096 9.73e-275 - - - EGP - - - Transmembrane secretion effector
MEPAFCOE_02097 5.06e-298 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
MEPAFCOE_02098 1.55e-275 arcT - - E - - - Aminotransferase
MEPAFCOE_02099 0.0 arcD - - E ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
MEPAFCOE_02100 2.48e-252 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MEPAFCOE_02101 1.15e-300 arcA 3.5.3.6 - E ko:K01478 ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130 ko00000,ko00001,ko01000 Arginine
MEPAFCOE_02102 0.0 - - - S - - - C4-dicarboxylate anaerobic carrier
MEPAFCOE_02103 1.45e-296 ycbA 2.7.13.3 - T ko:K07706,ko:K07717 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 histidine kinase DNA gyrase B
MEPAFCOE_02104 4.38e-74 - - - G - - - symporter
MEPAFCOE_02105 9.06e-167 - - - K - - - helix_turn_helix, arabinose operon control protein
MEPAFCOE_02106 0.0 - - - - - - - -
MEPAFCOE_02107 0.0 araB 2.7.1.16 - G ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 carbohydrate kinase FGGY
MEPAFCOE_02108 5.47e-178 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
MEPAFCOE_02109 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
MEPAFCOE_02110 1.36e-119 maa 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
MEPAFCOE_02111 3.23e-200 - - - L - - - Initiator Replication protein
MEPAFCOE_02112 1.58e-83 - - - - - - - -
MEPAFCOE_02113 0.0 - - - L - - - helicase
MEPAFCOE_02114 3.2e-76 - - - T ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
MEPAFCOE_02115 2.22e-59 - - - T ko:K07172 - ko00000,ko02048 Antidote-toxin recognition MazE, bacterial antitoxin
MEPAFCOE_02116 8.88e-138 - - - L - - - Integrase
MEPAFCOE_02117 1.24e-39 - - - - - - - -
MEPAFCOE_02118 2.85e-234 gbuA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
MEPAFCOE_02119 4.63e-143 gbuB - - E ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
MEPAFCOE_02120 1.3e-125 gbuC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
MEPAFCOE_02121 2.22e-236 - - - L - - - PFAM Integrase catalytic region
MEPAFCOE_02122 9.23e-154 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
MEPAFCOE_02123 7.73e-33 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
MEPAFCOE_02124 1.17e-129 pinR1 - - L - - - Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
MEPAFCOE_02126 6.06e-174 - - - E - - - GDSL-like Lipase/Acylhydrolase family
MEPAFCOE_02127 1.23e-135 - - - - - - - -
MEPAFCOE_02128 7.02e-146 azo1 1.5.1.36, 1.7.1.6 - S ko:K03206,ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
MEPAFCOE_02129 0.0 - - - M - - - MucBP domain
MEPAFCOE_02130 6.68e-86 - - - - - - - -
MEPAFCOE_02131 7.02e-36 - - - K ko:K07729 - ko00000,ko03000 Transcriptional
MEPAFCOE_02132 3.88e-285 - - - LO ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
MEPAFCOE_02133 8.42e-149 cah 4.2.1.1 - P ko:K01674 ko00910,map00910 ko00000,ko00001,ko01000 Eukaryotic-type carbonic anhydrase
MEPAFCOE_02134 4.45e-151 - - - - - - - -
MEPAFCOE_02135 1.14e-153 lacA 2.3.1.18, 2.3.1.79 - S ko:K00633,ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
MEPAFCOE_02136 5.91e-42 traI 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 This gene contains a nucleotide ambiguity which may be the result of a sequencing error
MEPAFCOE_02137 7.72e-65 traI 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 This gene contains a nucleotide ambiguity which may be the result of a sequencing error
MEPAFCOE_02138 0.0 traA - - L - - - MobA MobL family protein
MEPAFCOE_02139 6.64e-35 - - - - - - - -
MEPAFCOE_02140 4.05e-53 - - - - - - - -
MEPAFCOE_02141 5.94e-69 - - - Q - - - Methyltransferase
MEPAFCOE_02142 1.14e-40 crtF - - Q - - - methyltransferase
MEPAFCOE_02143 2.38e-176 repA - - S - - - Replication initiator protein A
MEPAFCOE_02145 8.87e-173 - - - D ko:K03496 - ko00000,ko03036,ko04812 CobQ CobB MinD ParA nucleotide binding domain protein
MEPAFCOE_02146 3.6e-115 - - - K - - - Bacterial regulatory proteins, tetR family
MEPAFCOE_02147 2.56e-119 perR - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
MEPAFCOE_02148 2.09e-146 - - - S - - - VIT family
MEPAFCOE_02149 1.12e-153 - - - S - - - membrane
MEPAFCOE_02150 0.0 ybeC - - E - - - amino acid
MEPAFCOE_02151 3.62e-105 yoaA - - J - - - COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MEPAFCOE_02152 2.9e-253 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
MEPAFCOE_02154 4.7e-50 - - - KLT - - - Protein kinase domain
MEPAFCOE_02155 1.86e-306 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MEPAFCOE_02156 3.1e-305 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
MEPAFCOE_02157 1.72e-40 - - - - - - - -
MEPAFCOE_02158 4.24e-78 - - - K - - - Winged helix DNA-binding domain
MEPAFCOE_02159 0.0 - - - S ko:K13730 ko05100,map05100 ko00000,ko00001 Uncharacterized protein conserved in bacteria (DUF2252)
MEPAFCOE_02160 0.0 - - - K - - - Mga helix-turn-helix domain
MEPAFCOE_02161 4.4e-47 - - - - - - - -
MEPAFCOE_02162 2.73e-146 - - - U ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
MEPAFCOE_02164 3.28e-63 - - - - - - - -
MEPAFCOE_02165 6.36e-145 nt5e 3.1.3.18 - L ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 haloacid dehalogenase-like hydrolase
MEPAFCOE_02166 0.0 pepE 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
MEPAFCOE_02167 1.4e-233 - - - C - - - Oxidoreductase
MEPAFCOE_02168 5.95e-105 - - - K - - - LysR substrate binding domain
MEPAFCOE_02169 7.4e-98 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
MEPAFCOE_02170 3.92e-141 sip3 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
MEPAFCOE_02171 1.76e-275 tcaB - - EGP ko:K07552 - ko00000,ko02000 Drug resistance transporter Bcr CflA subfamily
MEPAFCOE_02172 1.15e-280 - - - S - - - module of peptide synthetase
MEPAFCOE_02173 1.45e-119 ykhA 3.1.2.20 - I ko:K01073 - ko00000,ko01000 Thioesterase superfamily
MEPAFCOE_02174 4.33e-127 - - - J - - - Acetyltransferase (GNAT) domain
MEPAFCOE_02175 2.68e-142 - - - S ko:K07118 - ko00000 NAD(P)H-binding
MEPAFCOE_02176 1.34e-312 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
MEPAFCOE_02177 2.62e-49 - - - - - - - -
MEPAFCOE_02178 1.62e-158 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
MEPAFCOE_02179 4.81e-50 - - - - - - - -
MEPAFCOE_02180 4.46e-81 - - - - - - - -
MEPAFCOE_02181 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MEPAFCOE_02182 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MEPAFCOE_02183 2.25e-149 jag - - S ko:K06346 - ko00000 R3H domain protein
MEPAFCOE_02184 1.67e-185 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MEPAFCOE_02185 9.04e-78 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MEPAFCOE_02186 1.61e-20 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
MEPAFCOE_02187 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MEPAFCOE_02188 1.93e-265 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MEPAFCOE_02189 9.18e-49 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain protein YaaA
MEPAFCOE_02190 2.66e-270 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MEPAFCOE_02191 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MEPAFCOE_02192 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MEPAFCOE_02193 1.36e-65 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
MEPAFCOE_02194 5.15e-104 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MEPAFCOE_02195 1.33e-47 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MEPAFCOE_02196 6.05e-293 - - - Q - - - Imidazolonepropionase and related amidohydrolases
MEPAFCOE_02197 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MEPAFCOE_02198 1.38e-179 - - - - - - - -
MEPAFCOE_02199 1.87e-291 - - - Q - - - Imidazolonepropionase and related amidohydrolases
MEPAFCOE_02200 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MEPAFCOE_02201 8.93e-130 - - - K - - - Bacterial regulatory proteins, tetR family
MEPAFCOE_02202 4.07e-52 - - - S - - - response to heat
MEPAFCOE_02203 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
MEPAFCOE_02204 5.23e-91 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
MEPAFCOE_02207 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
MEPAFCOE_02208 7.83e-128 - - - S - - - NADPH-dependent FMN reductase
MEPAFCOE_02209 1.43e-267 yttB - - EGP - - - Major Facilitator
MEPAFCOE_02210 1.96e-36 - - - - - - - -
MEPAFCOE_02211 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MEPAFCOE_02212 9.34e-49 - - - - - - - -
MEPAFCOE_02213 4.5e-144 - - - E - - - Matrixin
MEPAFCOE_02215 1.19e-170 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
MEPAFCOE_02216 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MEPAFCOE_02217 4.78e-307 yycH - - S - - - YycH protein
MEPAFCOE_02218 1.09e-189 yycI - - S - - - YycH protein
MEPAFCOE_02219 2.33e-200 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
MEPAFCOE_02220 4.64e-271 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
MEPAFCOE_02221 5.2e-108 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MEPAFCOE_02223 8.3e-117 - - - - - - - -
MEPAFCOE_02224 4.65e-191 - - - F ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
MEPAFCOE_02225 1.75e-29 - - - - - - - -
MEPAFCOE_02226 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MEPAFCOE_02227 3.23e-195 rhaS2 - - K - - - Transcriptional regulator, AraC family
MEPAFCOE_02228 0.0 - - - G ko:K03292 - ko00000 MFS/sugar transport protein
MEPAFCOE_02229 0.0 xynB 3.2.1.37 GH43 G ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
MEPAFCOE_02230 0.0 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
MEPAFCOE_02231 1.13e-205 - - - - - - - -
MEPAFCOE_02232 1.36e-132 tnpR - - L - - - Resolvase, N terminal domain
MEPAFCOE_02233 7.04e-247 - - - L - - - Transposase and inactivated derivatives, IS30 family
MEPAFCOE_02234 0.0 ybeC - - E - - - amino acid
MEPAFCOE_02235 9.61e-05 - - - S - - - HTH domain
MEPAFCOE_02237 5.74e-30 - - - K - - - Helix-turn-helix XRE-family like proteins
MEPAFCOE_02238 2.9e-38 - - - L - - - transposase and inactivated derivatives, IS30 family
MEPAFCOE_02239 1.41e-58 - - - S - - - TIR domain
MEPAFCOE_02240 9.82e-55 - - - - - - - -
MEPAFCOE_02241 2.2e-223 - - - L - - - Initiator Replication protein
MEPAFCOE_02242 2e-37 - - - - - - - -
MEPAFCOE_02243 4.97e-81 - - - - - - - -
MEPAFCOE_02244 2.92e-103 - - - L - - - Integrase
MEPAFCOE_02245 1.02e-298 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MEPAFCOE_02246 5.91e-298 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MEPAFCOE_02247 3.22e-141 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
MEPAFCOE_02248 4.51e-69 - - - S - - - mazG nucleotide pyrophosphohydrolase
MEPAFCOE_02249 1.21e-22 - - - - - - - -
MEPAFCOE_02250 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MEPAFCOE_02251 3.98e-314 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MEPAFCOE_02254 1.06e-95 - - - - - - - -
MEPAFCOE_02255 1.92e-118 - - - - - - - -
MEPAFCOE_02256 1.94e-124 - - - P - - - Cadmium resistance transporter
MEPAFCOE_02257 4.7e-157 - - - K ko:K03709 - ko00000,ko03000 Helix-turn-helix diphteria tox regulatory element
MEPAFCOE_02258 2.77e-94 usp1 - - T - - - Universal stress protein family
MEPAFCOE_02259 0.0 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
MEPAFCOE_02260 0.0 rafA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
MEPAFCOE_02261 6.04e-94 - - - S - - - Iron-sulphur cluster biosynthesis
MEPAFCOE_02262 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
MEPAFCOE_02263 0.0 arcD - - E ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
MEPAFCOE_02264 9.55e-286 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MEPAFCOE_02265 2.22e-206 - - - S - - - Tetratricopeptide repeat
MEPAFCOE_02266 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MEPAFCOE_02267 2.9e-56 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MEPAFCOE_02268 8e-45 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
MEPAFCOE_02269 1.82e-119 - - - - - - - -
MEPAFCOE_02270 1.02e-50 - - - K - - - transcriptional regulator
MEPAFCOE_02271 1.22e-246 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MEPAFCOE_02272 7.85e-209 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MEPAFCOE_02273 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MEPAFCOE_02274 5.23e-125 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
MEPAFCOE_02275 0.0 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MEPAFCOE_02276 4.64e-124 yabR - - J ko:K07571 - ko00000 RNA binding
MEPAFCOE_02277 1.3e-69 - - - S - - - WxL domain surface cell wall-binding
MEPAFCOE_02278 1.14e-233 - - - S - - - Bacterial protein of unknown function (DUF916)
MEPAFCOE_02279 9.04e-78 - - - S - - - Bacterial toxin of type II toxin-antitoxin system, YafQ
MEPAFCOE_02280 1.11e-59 - - - D ko:K19159 - ko00000,ko02048 Antitoxin component of a toxin-antitoxin (TA) module
MEPAFCOE_02281 5.14e-137 - - - L - - - Integrase
MEPAFCOE_02282 7.68e-84 - - - - - - - -
MEPAFCOE_02283 1.66e-42 - - - - - - - -
MEPAFCOE_02284 3.26e-225 - - - L - - - Initiator Replication protein
MEPAFCOE_02285 4.68e-66 - - - - - - - -
MEPAFCOE_02286 4.1e-105 nrdI - - F ko:K03647 - ko00000 NrdI Flavodoxin like
MEPAFCOE_02287 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MEPAFCOE_02288 5.59e-220 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Ribonucleotide reductase, small chain
MEPAFCOE_02289 1.34e-231 - 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Ribonucleotide reductase, small chain
MEPAFCOE_02290 1.98e-137 - - - L ko:K07497 - ko00000 hmm pf00665
MEPAFCOE_02291 7.08e-63 - - - L - - - Resolvase, N terminal domain
MEPAFCOE_02292 1.1e-210 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
MEPAFCOE_02293 9.91e-241 lplL 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Bacterial lipoate protein ligase C-terminus
MEPAFCOE_02294 0.0 - - - E ko:K03294 - ko00000 Amino Acid
MEPAFCOE_02295 1.27e-250 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
MEPAFCOE_02296 1.68e-103 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
MEPAFCOE_02297 1.58e-281 ribA 3.5.4.25, 4.1.99.12 - H ko:K02858,ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
MEPAFCOE_02298 1.57e-134 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
MEPAFCOE_02299 1.79e-250 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MEPAFCOE_02300 2.3e-150 ktrA - - P ko:K03499 - ko00000,ko02000 domain protein
MEPAFCOE_02301 3.64e-306 ktrB - - P ko:K03498 - ko00000,ko02000 Potassium uptake protein
MEPAFCOE_02302 5.05e-153 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
MEPAFCOE_02303 6.61e-54 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
MEPAFCOE_02304 3.52e-83 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
MEPAFCOE_02305 6.51e-103 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MEPAFCOE_02306 1.64e-195 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MEPAFCOE_02307 2.29e-182 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MEPAFCOE_02308 3.08e-208 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MEPAFCOE_02309 4.65e-193 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MEPAFCOE_02310 6.64e-82 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
MEPAFCOE_02311 2.1e-219 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MEPAFCOE_02312 6.34e-81 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MEPAFCOE_02313 2.37e-79 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MEPAFCOE_02314 2.92e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MEPAFCOE_02315 3.43e-156 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MEPAFCOE_02316 1.59e-302 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MEPAFCOE_02317 1.95e-89 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
MEPAFCOE_02318 1.2e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
MEPAFCOE_02319 3.46e-110 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MEPAFCOE_02320 8.69e-76 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MEPAFCOE_02321 1.44e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MEPAFCOE_02322 3.78e-88 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MEPAFCOE_02323 3.53e-123 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MEPAFCOE_02324 4.1e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MEPAFCOE_02325 1.04e-78 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MEPAFCOE_02326 3.69e-54 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MEPAFCOE_02327 3.87e-34 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
MEPAFCOE_02328 3.95e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MEPAFCOE_02329 1.63e-154 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MEPAFCOE_02330 9.77e-73 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MEPAFCOE_02331 7.56e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MEPAFCOE_02332 2.32e-199 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MEPAFCOE_02333 4.65e-58 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MEPAFCOE_02334 6.37e-137 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
MEPAFCOE_02335 1.19e-150 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MEPAFCOE_02336 4.46e-66 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
MEPAFCOE_02337 5.98e-242 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
MEPAFCOE_02338 7.85e-28 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
MEPAFCOE_02339 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MEPAFCOE_02340 5.89e-108 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MEPAFCOE_02341 1.46e-92 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MEPAFCOE_02342 1.29e-149 comC 3.4.23.43 - NOU ko:K02236 - ko00000,ko00002,ko01000,ko02044 Bacterial Peptidase A24 N-terminal domain
MEPAFCOE_02343 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MEPAFCOE_02344 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MEPAFCOE_02345 3.18e-134 - - - K - - - Bacterial regulatory proteins, tetR family
MEPAFCOE_02346 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MEPAFCOE_02347 2.31e-100 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
MEPAFCOE_02356 3.26e-277 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MEPAFCOE_02357 1.4e-146 dgk2 - - F - - - deoxynucleoside kinase
MEPAFCOE_02358 0.0 lysP - - E ko:K03293,ko:K11733 - ko00000,ko02000 amino acid
MEPAFCOE_02360 1.52e-195 - - - I - - - alpha/beta hydrolase fold
MEPAFCOE_02361 2.5e-155 - - - I - - - phosphatase
MEPAFCOE_02362 1.36e-96 - - - S - - - Threonine/Serine exporter, ThrE
MEPAFCOE_02363 4.22e-167 - - - S - - - Putative threonine/serine exporter
MEPAFCOE_02364 1.46e-155 mntR - - K ko:K03709 - ko00000,ko03000 iron dependent repressor
MEPAFCOE_02365 4.51e-205 - - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
MEPAFCOE_02366 2.03e-130 - - - K - - - Acetyltransferase (GNAT) domain
MEPAFCOE_02367 0.0 traA - - L - - - MobA MobL family protein
MEPAFCOE_02368 1.91e-34 - - - - - - - -
MEPAFCOE_02369 5.98e-55 - - - - - - - -
MEPAFCOE_02370 8.3e-71 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
MEPAFCOE_02371 1.29e-73 - - - L - - - Transposase DDE domain
MEPAFCOE_02372 4.15e-170 - - - Q - - - Methyltransferase domain
MEPAFCOE_02373 0.0 - - - - - - - -
MEPAFCOE_02374 5.45e-257 xerS - - L ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family
MEPAFCOE_02375 1.6e-98 rppH3 - - F - - - NUDIX domain
MEPAFCOE_02376 2.23e-129 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MEPAFCOE_02377 1e-106 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
MEPAFCOE_02378 1.51e-96 traI 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 This gene contains a nucleotide ambiguity which may be the result of a sequencing error
MEPAFCOE_02379 1.1e-36 traI 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 This gene contains a nucleotide ambiguity which may be the result of a sequencing error
MEPAFCOE_02380 0.0 - - - L - - - MobA MobL family protein
MEPAFCOE_02381 1.98e-36 - - - - - - - -
MEPAFCOE_02382 4.05e-53 - - - - - - - -
MEPAFCOE_02383 2.25e-111 - - - - - - - -
MEPAFCOE_02384 5.71e-58 - - - L ko:K07473 - ko00000,ko02048 Addiction module antitoxin, RelB DinJ family
MEPAFCOE_02385 2.45e-68 repA - - S - - - Replication initiator protein A
MEPAFCOE_02386 1.38e-131 yvbG - - U ko:K05595 - ko00000,ko02000 MarC family integral membrane protein
MEPAFCOE_02387 4.21e-100 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
MEPAFCOE_02388 1.4e-137 tnpR - - L - - - Resolvase, N terminal domain
MEPAFCOE_02390 3.77e-247 - - - L - - - Transposase and inactivated derivatives, IS30 family
MEPAFCOE_02391 4.63e-259 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
MEPAFCOE_02392 4.34e-185 - - - - - - - -
MEPAFCOE_02393 2.11e-108 - - - T - - - Belongs to the universal stress protein A family
MEPAFCOE_02395 6.13e-258 yibE - - S - - - overlaps another CDS with the same product name
MEPAFCOE_02396 1.15e-163 yibF - - S - - - overlaps another CDS with the same product name
MEPAFCOE_02398 1.46e-64 - - - - - - - -
MEPAFCOE_02400 2.09e-30 - - - - - - - -
MEPAFCOE_02401 4.37e-79 - - - S - - - Bacteriophage holin family
MEPAFCOE_02403 2.69e-255 lysA2 - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
MEPAFCOE_02407 8.66e-13 - - - - - - - -
MEPAFCOE_02409 0.0 - - - S ko:K09955 - ko00000 Beta-L-arabinofuranosidase, GH127
MEPAFCOE_02410 4.17e-64 - - - K - - - AraC family transcriptional regulator
MEPAFCOE_02411 4.25e-128 - - - S - - - Putative glutamine amidotransferase
MEPAFCOE_02412 2.03e-171 - - - S ko:K09936 ko02024,map02024 ko00000,ko00001,ko02000 protein conserved in bacteria
MEPAFCOE_02413 2.48e-189 - 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
MEPAFCOE_02414 1.34e-299 arcA 3.5.3.6 - E ko:K01478 ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130 ko00000,ko00001,ko01000 Arginine
MEPAFCOE_02416 1.04e-32 qorB 1.6.5.2 - GM ko:K19267 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NmrA-like family
MEPAFCOE_02417 2.83e-61 qorB 1.6.5.2 - GM ko:K19267 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NmrA-like family
MEPAFCOE_02418 7.07e-92 ywnA - - K - - - Transcriptional regulator
MEPAFCOE_02419 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
MEPAFCOE_02420 9.12e-237 lacM 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase
MEPAFCOE_02421 3.46e-51 - - - K - - - MerR, DNA binding
MEPAFCOE_02422 6.38e-192 - - - K - - - LysR substrate binding domain
MEPAFCOE_02423 4.95e-248 - 1.1.1.90 - C ko:K00055 ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Zn-dependent alcohol dehydrogenases, class III
MEPAFCOE_02424 3.68e-43 - - - S - - - YjbR
MEPAFCOE_02425 1.9e-129 - - - S - - - DJ-1/PfpI family
MEPAFCOE_02427 4.42e-292 gntP - - EG ko:K03299 - ko00000,ko02000 Gluconate
MEPAFCOE_02428 2.1e-304 - - - E ko:K03294 - ko00000 amino acid
MEPAFCOE_02429 9.26e-317 fucP - - G ko:K02429 - ko00000,ko02000 Major Facilitator Superfamily
MEPAFCOE_02430 5.83e-87 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
MEPAFCOE_02431 0.0 gshA 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
MEPAFCOE_02432 1.09e-307 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 pyrimidine-nucleoside phosphorylase
MEPAFCOE_02433 6.79e-222 deoR - - K ko:K05346 - ko00000,ko03000 sugar-binding domain protein
MEPAFCOE_02434 1.23e-166 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
MEPAFCOE_02435 2.2e-295 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
MEPAFCOE_02436 1.05e-155 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MEPAFCOE_02437 1.27e-50 - - - K - - - Helix-turn-helix XRE-family like proteins
MEPAFCOE_02438 1.06e-76 - - - K - - - Helix-turn-helix XRE-family like proteins
MEPAFCOE_02439 3.98e-185 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Pfam:Y_phosphatase3C
MEPAFCOE_02440 1.87e-248 namA - - C - - - Oxidoreductase
MEPAFCOE_02441 1.47e-72 - - - E ko:K04031 - ko00000 BMC
MEPAFCOE_02442 1.64e-281 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MEPAFCOE_02443 1.31e-269 pduQ - - C ko:K13921 ko00640,map00640 ko00000,ko00001 Iron-containing alcohol dehydrogenase
MEPAFCOE_02444 0.0 pduP 1.2.1.87 - C ko:K13922 ko00640,map00640 ko00000,ko00001,ko01000 Aldehyde dehydrogenase family
MEPAFCOE_02445 7.1e-106 pduO - - S - - - Haem-degrading
MEPAFCOE_02446 7.33e-135 - - - S - - - Cobalamin adenosyltransferase
MEPAFCOE_02447 3.12e-56 pduN - - CQ ko:K04028 - ko00000 Ethanolamine utilisation protein EutN/carboxysome
MEPAFCOE_02448 1.51e-116 - - - S - - - Putative propanediol utilisation
MEPAFCOE_02449 4.89e-146 pduL 2.3.1.222 - Q ko:K13923 ko00640,map00640 ko00000,ko00001,ko01000 Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate
MEPAFCOE_02450 3.38e-56 pduJ - - CQ - - - BMC
MEPAFCOE_02451 1.13e-108 - - - CQ - - - BMC
MEPAFCOE_02452 2.32e-75 pduH - - S - - - Dehydratase medium subunit
MEPAFCOE_02453 0.0 pduG - - D - - - Diol dehydratase reactivase ATPase-like domain
MEPAFCOE_02454 2.23e-119 pduE 4.2.1.28 - Q ko:K13920 ko00640,map00640 ko00000,ko00001,ko01000 Dehydratase small subunit
MEPAFCOE_02455 2.9e-167 pduD 4.2.1.28 - Q ko:K13919 ko00640,map00640 ko00000,ko00001,ko01000 Dehydratase medium subunit
MEPAFCOE_02456 0.0 pduC 4.2.1.28 - Q ko:K01699 ko00640,map00640 ko00000,ko00001,ko01000 Dehydratase large subunit
MEPAFCOE_02457 1.56e-166 pduB - - E - - - BMC
MEPAFCOE_02458 1.47e-55 - - - CQ - - - BMC
MEPAFCOE_02459 5.72e-263 - - - K - - - helix_turn_helix, arabinose operon control protein
MEPAFCOE_02460 4.82e-164 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
MEPAFCOE_02461 3.37e-56 eutP - - E ko:K04029 - ko00000 Ethanolamine utilisation - propanediol utilisation
MEPAFCOE_02462 0.0 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MEPAFCOE_02463 1.57e-237 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
MEPAFCOE_02464 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MEPAFCOE_02465 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MEPAFCOE_02466 4.8e-66 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MEPAFCOE_02467 1.33e-257 camS - - S - - - sex pheromone
MEPAFCOE_02468 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MEPAFCOE_02469 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
MEPAFCOE_02470 2.47e-274 purK2 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MEPAFCOE_02471 1.86e-128 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MEPAFCOE_02472 2.14e-205 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
MEPAFCOE_02473 5e-227 hepT 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
MEPAFCOE_02474 0.0 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
MEPAFCOE_02475 0.0 cydC - - CO ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
MEPAFCOE_02476 6.5e-224 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase subunit II
MEPAFCOE_02477 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
MEPAFCOE_02478 9.76e-229 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
MEPAFCOE_02479 1.47e-182 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MEPAFCOE_02480 2.27e-151 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
MEPAFCOE_02481 1.05e-116 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
MEPAFCOE_02482 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
MEPAFCOE_02483 1.1e-234 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
MEPAFCOE_02484 3.39e-67 azlD - - S - - - Branched-chain amino acid transport protein (AzlD)
MEPAFCOE_02485 1.68e-139 azlC - - E - - - branched-chain amino acid
MEPAFCOE_02486 5.16e-50 - - - K - - - MerR HTH family regulatory protein
MEPAFCOE_02487 4.36e-154 - - - S - - - Domain of unknown function (DUF4811)
MEPAFCOE_02488 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
MEPAFCOE_02489 7.65e-101 - - - K - - - MerR HTH family regulatory protein
MEPAFCOE_02490 0.0 - - - - - - - -
MEPAFCOE_02491 1.54e-177 - - - E - - - IrrE N-terminal-like domain
MEPAFCOE_02492 4.68e-10 - - - S - - - Domain of unknown function (DUF4411)
MEPAFCOE_02493 4.26e-133 - - - - - - - -
MEPAFCOE_02494 3.18e-180 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MEPAFCOE_02495 1.62e-227 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
MEPAFCOE_02496 7.73e-109 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
MEPAFCOE_02497 5.48e-114 - - - J - - - Acetyltransferase (GNAT) domain
MEPAFCOE_02498 4.56e-244 tas3 - - C ko:K19265 - ko00000,ko01000 Aldo keto reductase family protein
MEPAFCOE_02499 2.08e-133 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MEPAFCOE_02500 4.23e-217 whiA - - K ko:K09762 - ko00000 May be required for sporulation
MEPAFCOE_02501 3.47e-244 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
MEPAFCOE_02502 5.33e-211 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
MEPAFCOE_02503 7.81e-46 - - - - - - - -
MEPAFCOE_02504 4.75e-63 - - - L - - - Psort location Cytoplasmic, score
MEPAFCOE_02505 3.99e-47 - - - L - - - Psort location Cytoplasmic, score
MEPAFCOE_02506 3.35e-121 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
MEPAFCOE_02507 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
MEPAFCOE_02510 0.0 - - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 ABC transporter
MEPAFCOE_02511 0.0 katA 1.11.1.6 - C ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 Belongs to the catalase family
MEPAFCOE_02512 2.31e-242 rsgA_2 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MEPAFCOE_02513 4.8e-187 - - - C - - - Aldo/keto reductase family
MEPAFCOE_02514 7.64e-125 laaE - - K - - - Transcriptional regulator PadR-like family
MEPAFCOE_02515 3.77e-84 lysM - - M - - - LysM domain
MEPAFCOE_02516 7.4e-165 XK27_07210 - - S - - - B3 4 domain
MEPAFCOE_02517 4.82e-155 - - - K ko:K10914,ko:K21828 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 Cyclic nucleotide-monophosphate binding domain
MEPAFCOE_02518 1.27e-219 arcC 2.7.2.2 - E ko:K00926 ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200 ko00000,ko00001,ko01000 Belongs to the carbamate kinase family
MEPAFCOE_02519 2.61e-132 pncA - - Q - - - Isochorismatase family
MEPAFCOE_02520 0.0 nadC2 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MEPAFCOE_02521 1.37e-167 - - - F - - - NUDIX domain

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)