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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
CIGNPGHA_00001	7.88e-26	yobV3	-	-	K	-	-	-	WYL domain
CIGNPGHA_00002	6.07e-15	yobV3	-	-	K	-	-	-	Transcriptional regulator
CIGNPGHA_00003	4.97e-168	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
CIGNPGHA_00004	2.31e-110	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
CIGNPGHA_00005	0.0	-	-	-	S	ko:K18231,ko:K19349	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ATPases associated with a variety of cellular activities
CIGNPGHA_00006	8.73e-314	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
CIGNPGHA_00008	2.81e-183	kduD	1.1.1.127	-	IQ	ko:K00065	ko00040,map00040	ko00000,ko00001,ko01000	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CIGNPGHA_00009	1.27e-223	-	-	-	K	ko:K02525	-	ko00000,ko03000	Transcriptional regulator, LacI family
CIGNPGHA_00010	3.04e-68	-	-	-	K	-	-	-	transcriptional regulator
CIGNPGHA_00011	9.8e-134	-	-	-	S	-	-	-	Enoyl-(Acyl carrier protein) reductase
CIGNPGHA_00012	4.06e-315	yhdP	-	-	S	-	-	-	Transporter associated domain
CIGNPGHA_00013	1.62e-80	-	-	-	-	-	-	-	-
CIGNPGHA_00014	1.19e-93	hsp1	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
CIGNPGHA_00015	0.0	-	-	-	E	-	-	-	Amino Acid
CIGNPGHA_00016	2.74e-207	yvgN	-	-	S	-	-	-	Aldo keto reductase
CIGNPGHA_00017	6.97e-05	-	-	-	-	-	-	-	-
CIGNPGHA_00018	0.0	yfgQ	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
CIGNPGHA_00019	8.76e-121	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
CIGNPGHA_00020	0.0	glpQ4	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
CIGNPGHA_00021	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
CIGNPGHA_00022	6.43e-104	-	-	-	M	-	-	-	LysM domain protein
CIGNPGHA_00023	0.0	-	-	-	M	-	-	-	Leucine-rich repeat (LRR) protein
CIGNPGHA_00024	1.64e-88	-	-	-	M	-	-	-	LysM domain protein
CIGNPGHA_00026	3.71e-76	lysM	-	-	M	-	-	-	LysM domain
CIGNPGHA_00028	1.13e-125	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
CIGNPGHA_00029	9.6e-212	kduI	5.3.1.17	-	G	ko:K01815	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
CIGNPGHA_00030	3.5e-223	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	pfkB family carbohydrate kinase
CIGNPGHA_00031	2.23e-279	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CIGNPGHA_00032	2.12e-78	-	-	-	S	-	-	-	3D domain
CIGNPGHA_00033	0.0	-	-	-	M	ko:K01992	-	ko00000,ko00002,ko02000	Exporter of polyketide antibiotics
CIGNPGHA_00034	7.01e-213	ybhF_1	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
CIGNPGHA_00035	7.18e-153	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
CIGNPGHA_00036	9.34e-317	-	-	-	V	-	-	-	MatE
CIGNPGHA_00037	0.0	uxaC	5.3.1.12	-	G	ko:K01812	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	glucuronate isomerase
CIGNPGHA_00038	0.0	-	-	-	G	ko:K03292	-	ko00000	MFS/sugar transport protein
CIGNPGHA_00039	0.0	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
CIGNPGHA_00040	3.1e-209	-	-	-	EG	ko:K16321	-	ko00000,ko02000	GntP family permease
CIGNPGHA_00041	1.7e-104	eda	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	KDPG and KHG aldolase
CIGNPGHA_00042	2.17e-135	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	pfkB family carbohydrate kinase
CIGNPGHA_00043	5.33e-305	uxaC	5.3.1.12	-	G	ko:K01812	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	glucuronate isomerase
CIGNPGHA_00044	1.15e-46	-	-	-	-	-	-	-	-
CIGNPGHA_00045	0.0	uxuT	-	-	G	ko:K03292,ko:K16210	-	ko00000,ko02000	MFS/sugar transport protein
CIGNPGHA_00046	7.56e-119	kdgR	-	-	K	-	-	-	FCD domain
CIGNPGHA_00047	1.76e-257	uxuA	4.2.1.8	-	G	ko:K01686	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of D-mannonate
CIGNPGHA_00048	0.0	uxuB	1.1.1.57	-	G	ko:K00040	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Mannitol dehydrogenase C-terminal domain
CIGNPGHA_00049	1.12e-211	yqhA	-	-	G	-	-	-	Aldose 1-epimerase
CIGNPGHA_00050	1.19e-152	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
CIGNPGHA_00051	1.41e-240	-	-	-	C	-	-	-	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CIGNPGHA_00052	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
CIGNPGHA_00053	2.36e-217	gntZ	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
CIGNPGHA_00054	3.54e-165	-	-	-	K	-	-	-	FCD domain
CIGNPGHA_00055	9.16e-266	uxuA	4.2.1.8	-	G	ko:K01686	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of D-mannonate
CIGNPGHA_00056	4.5e-235	exuR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding protein domain
CIGNPGHA_00057	0.0	-	-	-	G	ko:K03292	-	ko00000	MFS/sugar transport protein
CIGNPGHA_00058	0.0	-	5.1.2.7	-	S	ko:K21619	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	tagaturonate epimerase
CIGNPGHA_00059	0.0	uxaC	5.3.1.12	-	G	ko:K01812	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	glucuronate isomerase
CIGNPGHA_00060	1.37e-289	-	-	-	S	-	-	-	module of peptide synthetase
CIGNPGHA_00062	0.0	-	-	-	EGP	-	-	-	Major Facilitator
CIGNPGHA_00065	7.28e-175	-	-	-	-	-	-	-	-
CIGNPGHA_00066	5.77e-118	ebsC	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CIGNPGHA_00067	1.75e-169	gntR1	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
CIGNPGHA_00068	4.33e-161	zmp3	-	-	O	-	-	-	Zinc-dependent metalloprotease
CIGNPGHA_00069	1.68e-109	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
CIGNPGHA_00070	6.37e-102	-	-	-	-	-	-	-	-
CIGNPGHA_00071	2.4e-181	agrA	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
CIGNPGHA_00072	1.53e-304	pltK	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
CIGNPGHA_00073	1.48e-281	-	-	-	T	-	-	-	protein histidine kinase activity
CIGNPGHA_00074	3.97e-173	-	-	-	IQ	-	-	-	Oxidoreductase, short chain dehydrogenase reductase family protein
CIGNPGHA_00076	6.32e-224	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
CIGNPGHA_00077	4.19e-101	uspA3	-	-	T	-	-	-	universal stress protein
CIGNPGHA_00078	8.87e-49	-	-	-	EGP	-	-	-	Major Facilitator
CIGNPGHA_00079	2.3e-150	-	-	-	EGP	-	-	-	Major Facilitator
CIGNPGHA_00080	1.55e-64	-	-	-	K	-	-	-	transcriptional regulator
CIGNPGHA_00081	0.0	oppA1	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
CIGNPGHA_00082	3.95e-224	oppC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CIGNPGHA_00083	1.14e-229	oppB	-	-	P	ko:K02033,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
CIGNPGHA_00084	5.64e-228	oppF	-	-	P	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
CIGNPGHA_00085	1.08e-243	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
CIGNPGHA_00086	3.7e-101	-	-	-	K	-	-	-	Winged helix-turn-helix transcription repressor, HrcA DNA-binding
CIGNPGHA_00087	6.05e-250	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
CIGNPGHA_00088	8.07e-91	-	-	-	-	-	-	-	-
CIGNPGHA_00089	2.68e-62	-	-	-	-	-	-	-	-
CIGNPGHA_00090	0.0	xylA	5.3.1.5	-	G	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko01000	Belongs to the xylose isomerase family
CIGNPGHA_00091	0.0	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Xylulose kinase
CIGNPGHA_00092	5.73e-288	xylT	-	-	EGP	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
CIGNPGHA_00094	7.71e-182	budC	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	reductase
CIGNPGHA_00095	5.97e-79	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
CIGNPGHA_00096	1.44e-141	-	-	-	S	-	-	-	membrane
CIGNPGHA_00097	0.0	-	-	-	S	-	-	-	membrane
CIGNPGHA_00098	1.06e-116	usp5	-	-	T	-	-	-	universal stress protein
CIGNPGHA_00099	2.26e-125	yxkA	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
CIGNPGHA_00100	2.14e-279	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
CIGNPGHA_00101	3.72e-160	-	-	-	P	ko:K10716	-	ko00000,ko02000	Ion channel
CIGNPGHA_00102	2.16e-77	-	-	-	-	-	-	-	-
CIGNPGHA_00103	7.25e-216	-	-	-	C	-	-	-	Aldo keto reductase
CIGNPGHA_00104	5.43e-91	-	-	-	-	-	-	-	-
CIGNPGHA_00105	1.9e-121	-	-	-	S	-	-	-	Acetyltransferase (GNAT) family
CIGNPGHA_00106	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
CIGNPGHA_00107	2.42e-241	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
CIGNPGHA_00108	2.17e-241	idhA	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CIGNPGHA_00109	0.0	yufL	2.7.13.3	-	T	ko:K02476,ko:K11614	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Single cache domain 3
CIGNPGHA_00110	6.8e-161	dctR	-	-	K	ko:K02475,ko:K11692	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	cheY-homologous receiver domain
CIGNPGHA_00111	3.66e-280	-	-	-	S	-	-	-	ABC-2 family transporter protein
CIGNPGHA_00112	8.52e-130	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
CIGNPGHA_00113	2.83e-159	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
CIGNPGHA_00114	2.24e-123	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
CIGNPGHA_00115	9.87e-183	-	-	-	S	-	-	-	zinc-ribbon domain
CIGNPGHA_00116	0.0	-	-	-	S	-	-	-	response to antibiotic
CIGNPGHA_00117	4.33e-109	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
CIGNPGHA_00119	4.36e-87	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
CIGNPGHA_00120	1.64e-108	padR	-	-	K	-	-	-	Virulence activator alpha C-term
CIGNPGHA_00121	2.28e-132	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
CIGNPGHA_00122	1.28e-232	-	1.1.1.219	-	GM	ko:K00091	-	ko00000,ko01000	Male sterility protein
CIGNPGHA_00123	4.95e-98	-	-	-	S	ko:K02348	-	ko00000	Gnat family
CIGNPGHA_00124	5.75e-103	yybA	-	-	K	-	-	-	Transcriptional regulator
CIGNPGHA_00128	0.0	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CIGNPGHA_00129	1.02e-46	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CIGNPGHA_00130	8.72e-301	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
CIGNPGHA_00131	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CIGNPGHA_00132	8.25e-25	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
CIGNPGHA_00133	2e-248	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
CIGNPGHA_00134	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
CIGNPGHA_00135	2.51e-123	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CIGNPGHA_00136	8.18e-243	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
CIGNPGHA_00137	3.4e-229	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
CIGNPGHA_00138	7.03e-216	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CIGNPGHA_00139	1.77e-74	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CIGNPGHA_00140	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CIGNPGHA_00141	1.99e-59	ylxQ	-	-	J	-	-	-	ribosomal protein
CIGNPGHA_00142	2.64e-63	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
CIGNPGHA_00143	1.92e-251	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
CIGNPGHA_00144	3.03e-106	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
CIGNPGHA_00145	4.41e-52	-	-	-	-	-	-	-	-
CIGNPGHA_00146	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CIGNPGHA_00147	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
CIGNPGHA_00148	6.6e-294	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
CIGNPGHA_00149	1.31e-175	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
CIGNPGHA_00150	1.4e-190	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CIGNPGHA_00151	3.42e-97	-	-	-	-	-	-	-	-
CIGNPGHA_00152	2.83e-111	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
CIGNPGHA_00153	2.12e-165	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
CIGNPGHA_00154	2.79e-197	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CIGNPGHA_00155	5.38e-183	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
CIGNPGHA_00156	1.63e-173	-	-	-	S	ko:K07025	-	ko00000	Haloacid dehalogenase-like hydrolase
CIGNPGHA_00157	3.05e-236	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CIGNPGHA_00158	1.23e-57	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
CIGNPGHA_00159	2.3e-173	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
CIGNPGHA_00160	5.71e-152	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
CIGNPGHA_00161	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
CIGNPGHA_00162	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
CIGNPGHA_00163	1.61e-44	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
CIGNPGHA_00164	2.61e-49	ynzC	-	-	S	-	-	-	UPF0291 protein
CIGNPGHA_00165	2.41e-142	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CIGNPGHA_00166	1.66e-100	-	-	-	F	-	-	-	nucleoside 2-deoxyribosyltransferase
CIGNPGHA_00167	4.16e-107	-	-	-	-	-	-	-	-
CIGNPGHA_00168	1.18e-271	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
CIGNPGHA_00169	9.54e-209	-	-	-	S	-	-	-	Polyphosphate nucleotide phosphotransferase, PPK2 family
CIGNPGHA_00170	1.1e-157	pgm3	-	-	G	-	-	-	phosphoglycerate mutase
CIGNPGHA_00171	2.94e-34	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
CIGNPGHA_00172	2.06e-107	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
CIGNPGHA_00176	3.36e-91	-	-	-	S	-	-	-	TIR domain
CIGNPGHA_00177	2.96e-209	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
CIGNPGHA_00178	5.89e-98	-	-	-	-	-	-	-	-
CIGNPGHA_00179	6.11e-11	-	-	-	K	-	-	-	CsbD-like
CIGNPGHA_00180	7.24e-102	-	-	-	T	-	-	-	Universal stress protein family
CIGNPGHA_00181	1.03e-118	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CIGNPGHA_00182	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
CIGNPGHA_00183	3.64e-71	yrvD	-	-	S	-	-	-	Pfam:DUF1049
CIGNPGHA_00184	6.88e-230	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
CIGNPGHA_00185	1.59e-36	-	-	-	-	-	-	-	-
CIGNPGHA_00186	1.45e-157	-	-	-	-	-	-	-	-
CIGNPGHA_00187	0.0	katA	1.11.1.6	-	C	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	Belongs to the catalase family
CIGNPGHA_00188	2.31e-242	rsgA_2	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
CIGNPGHA_00189	4.8e-187	-	-	-	C	-	-	-	Aldo/keto reductase family
CIGNPGHA_00190	6.83e-274	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CIGNPGHA_00191	9.61e-155	-	-	-	-	-	-	-	-
CIGNPGHA_00192	2.78e-82	-	-	-	-	-	-	-	-
CIGNPGHA_00193	1.8e-134	-	-	-	-	-	-	-	-
CIGNPGHA_00194	3.44e-70	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
CIGNPGHA_00195	7.64e-125	laaE	-	-	K	-	-	-	Transcriptional regulator PadR-like family
CIGNPGHA_00196	3.77e-84	lysM	-	-	M	-	-	-	LysM domain
CIGNPGHA_00197	7.4e-165	XK27_07210	-	-	S	-	-	-	B3 4 domain
CIGNPGHA_00198	4.82e-155	-	-	-	K	ko:K10914,ko:K21828	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	Cyclic nucleotide-monophosphate binding domain
CIGNPGHA_00199	1.27e-219	arcC	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	Belongs to the carbamate kinase family
CIGNPGHA_00200	5.22e-08	-	-	-	-	-	-	-	-
CIGNPGHA_00201	4.46e-48	-	-	-	-	-	-	-	-
CIGNPGHA_00202	6.13e-127	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
CIGNPGHA_00204	1.37e-167	-	-	-	F	-	-	-	NUDIX domain
CIGNPGHA_00205	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CIGNPGHA_00206	2.61e-132	pncA	-	-	Q	-	-	-	Isochorismatase family
CIGNPGHA_00207	0.0	ybeC	-	-	E	-	-	-	amino acid
CIGNPGHA_00208	7.04e-247	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
CIGNPGHA_00209	4.22e-55	tnpR	-	-	L	-	-	-	Resolvase, N terminal domain
CIGNPGHA_00210	3.57e-213	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
CIGNPGHA_00211	1.2e-120	epsB	-	-	M	-	-	-	biosynthesis protein
CIGNPGHA_00212	3.74e-167	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
CIGNPGHA_00213	1.17e-178	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
CIGNPGHA_00214	6.06e-111	rfbP	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
CIGNPGHA_00215	2.09e-85	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
CIGNPGHA_00216	7.11e-231	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
CIGNPGHA_00217	7.29e-140	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
CIGNPGHA_00220	5.47e-85	-	-	-	D	-	-	-	AAA domain
CIGNPGHA_00221	8.83e-06	-	-	-	-	-	-	-	-
CIGNPGHA_00222	7.51e-97	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
CIGNPGHA_00223	3.55e-99	apfA	3.6.1.61	-	F	ko:K18445	ko00230,map00230	ko00000,ko00001,ko01000	Nudix hydrolase
CIGNPGHA_00224	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
CIGNPGHA_00225	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
CIGNPGHA_00226	3.67e-227	-	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
CIGNPGHA_00227	4.19e-113	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
CIGNPGHA_00228	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
CIGNPGHA_00229	1.57e-89	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
CIGNPGHA_00230	1.19e-161	XK27_07075	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
CIGNPGHA_00231	3.97e-156	-	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
CIGNPGHA_00232	4.7e-214	WQ51_06230	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
CIGNPGHA_00233	4.03e-215	XK27_00670	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
CIGNPGHA_00234	6.68e-206	-	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
CIGNPGHA_00235	4.81e-228	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
CIGNPGHA_00236	2.56e-196	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
CIGNPGHA_00237	1.61e-177	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
CIGNPGHA_00238	3.51e-82	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
CIGNPGHA_00239	8.39e-73	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
CIGNPGHA_00240	1.53e-146	-	-	-	S	-	-	-	Fn3-like domain
CIGNPGHA_00242	1.49e-282	-	-	-	-	-	-	-	-
CIGNPGHA_00244	1.2e-204	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
CIGNPGHA_00245	4.93e-164	-	-	-	P	-	-	-	integral membrane protein, YkoY family
CIGNPGHA_00246	1.87e-306	-	3.4.16.4	-	V	ko:K01286	-	ko00000,ko01000	SH3-like domain
CIGNPGHA_00247	1.77e-143	acmA	-	-	NU	-	-	-	mannosyl-glycoprotein
CIGNPGHA_00248	2.59e-231	-	-	-	S	-	-	-	DUF218 domain
CIGNPGHA_00249	1.16e-241	-	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
CIGNPGHA_00250	9.28e-171	-	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	reductase
CIGNPGHA_00251	2.21e-21	-	-	-	-	-	-	-	-
CIGNPGHA_00252	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
CIGNPGHA_00253	0.0	ydiC1	-	-	EGP	-	-	-	Major Facilitator
CIGNPGHA_00254	5.42e-117	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
CIGNPGHA_00255	3.41e-107	-	-	-	K	-	-	-	MerR family regulatory protein
CIGNPGHA_00256	6.48e-87	lytE	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family
CIGNPGHA_00257	3.26e-101	yyaT	-	-	K	ko:K02348	-	ko00000	protein acetylation
CIGNPGHA_00258	6.66e-159	pgm3	-	-	G	-	-	-	phosphoglycerate mutase family
CIGNPGHA_00259	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
CIGNPGHA_00260	5.02e-230	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
CIGNPGHA_00261	1.5e-180	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
CIGNPGHA_00262	1.65e-243	-	-	-	S	-	-	-	Protease prsW family
CIGNPGHA_00263	6.11e-229	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
CIGNPGHA_00264	6.95e-10	-	-	-	-	-	-	-	-
CIGNPGHA_00265	1.75e-129	-	-	-	-	-	-	-	-
CIGNPGHA_00266	7.18e-193	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
CIGNPGHA_00267	6.68e-198	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
CIGNPGHA_00268	4.73e-303	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CIGNPGHA_00269	4.01e-185	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2087)
CIGNPGHA_00270	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
CIGNPGHA_00271	4.8e-96	-	1.1.1.29	-	CH	ko:K00018	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CIGNPGHA_00272	5.24e-84	-	-	-	-	-	-	-	-
CIGNPGHA_00273	1.11e-70	-	-	-	-	-	-	-	-
CIGNPGHA_00274	0.0	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
CIGNPGHA_00275	1.53e-113	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
CIGNPGHA_00276	1.15e-57	-	-	-	L	ko:K07473	-	ko00000,ko02048	Addiction module antitoxin, RelB DinJ family
CIGNPGHA_00277	3.88e-38	-	-	-	-	-	-	-	-
CIGNPGHA_00278	1.47e-55	-	-	-	-	-	-	-	-
CIGNPGHA_00279	1.69e-37	-	-	-	-	-	-	-	-
CIGNPGHA_00280	1.94e-82	-	-	-	-	-	-	-	-
CIGNPGHA_00281	2.97e-136	-	-	-	L	-	-	-	Integrase
CIGNPGHA_00282	1.01e-119	-	-	-	O	-	-	-	Zinc-dependent metalloprotease
CIGNPGHA_00294	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
CIGNPGHA_00295	3.3e-131	-	-	-	S	-	-	-	Plasmid replication protein
CIGNPGHA_00296	1.35e-135	mob	-	-	D	-	-	-	Plasmid recombination enzyme
CIGNPGHA_00298	6.06e-174	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
CIGNPGHA_00299	1.23e-135	-	-	-	-	-	-	-	-
CIGNPGHA_00300	2.14e-174	-	-	-	I	-	-	-	alpha/beta hydrolase fold
CIGNPGHA_00301	7.42e-228	draG	-	-	O	-	-	-	ADP-ribosylglycohydrolase
CIGNPGHA_00302	6.17e-133	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
CIGNPGHA_00303	6.78e-102	-	-	-	-	-	-	-	-
CIGNPGHA_00304	2.99e-289	-	-	-	EK	-	-	-	Aminotransferase, class I
CIGNPGHA_00305	2.44e-211	-	-	-	K	-	-	-	LysR substrate binding domain
CIGNPGHA_00307	2.2e-128	-	-	-	K	-	-	-	DNA-templated transcription, initiation
CIGNPGHA_00308	3.57e-260	-	-	-	-	-	-	-	-
CIGNPGHA_00309	4.86e-84	-	-	-	-	-	-	-	-
CIGNPGHA_00310	3e-73	-	-	-	-	-	-	-	-
CIGNPGHA_00311	2.19e-249	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
CIGNPGHA_00312	2.56e-289	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
CIGNPGHA_00313	1.92e-24	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
CIGNPGHA_00314	7.05e-139	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
CIGNPGHA_00315	6.85e-189	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
CIGNPGHA_00316	1.48e-176	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CIGNPGHA_00317	1.01e-191	yneD	-	-	S	-	-	-	Enoyl-(Acyl carrier protein) reductase
CIGNPGHA_00318	2.26e-166	yjkA	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
CIGNPGHA_00319	8.74e-153	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
CIGNPGHA_00320	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CIGNPGHA_00321	2.14e-96	-	-	-	-	-	-	-	-
CIGNPGHA_00322	1.48e-114	rmeB	-	-	K	-	-	-	transcriptional regulator, MerR family
CIGNPGHA_00323	2.01e-123	-	-	-	J	-	-	-	glyoxalase III activity
CIGNPGHA_00324	2.4e-177	XK27_00890	-	-	S	ko:K08974	-	ko00000	Domain of unknown function (DUF368)
CIGNPGHA_00325	2.59e-171	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
CIGNPGHA_00326	8.48e-285	xylR	-	-	GK	-	-	-	ROK family
CIGNPGHA_00327	4.04e-204	-	-	-	C	-	-	-	Aldo keto reductase
CIGNPGHA_00328	5.68e-316	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
CIGNPGHA_00329	0.0	cpdB	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
CIGNPGHA_00330	3.15e-163	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
CIGNPGHA_00331	7.12e-226	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
CIGNPGHA_00332	0.0	pepF2	-	-	E	-	-	-	Oligopeptidase F
CIGNPGHA_00333	9.09e-97	-	-	-	K	-	-	-	Transcriptional regulator
CIGNPGHA_00334	1.86e-210	-	-	-	-	-	-	-	-
CIGNPGHA_00335	7.9e-247	-	-	-	S	-	-	-	DUF218 domain
CIGNPGHA_00336	8.73e-201	nanK	-	-	GK	-	-	-	ROK family
CIGNPGHA_00337	0.0	-	-	-	E	-	-	-	Amino acid permease
CIGNPGHA_00338	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
CIGNPGHA_00339	4.26e-23	-	-	-	S	-	-	-	SEC-C Motif Domain Protein
CIGNPGHA_00340	5.45e-268	-	-	-	S	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
CIGNPGHA_00342	9.83e-66	-	-	-	-	-	-	-	-
CIGNPGHA_00343	1.11e-100	-	-	-	K	ko:K06075	-	ko00000,ko03000	Winged helix DNA-binding domain
CIGNPGHA_00344	1.09e-141	nnrE	5.1.99.6	-	H	ko:K17759	-	ko00000,ko01000	Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
CIGNPGHA_00345	2.88e-130	aad	3.4.13.22	-	E	ko:K08641	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
CIGNPGHA_00346	6.4e-142	-	-	-	-	-	-	-	-
CIGNPGHA_00347	3.06e-238	yxeI	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
CIGNPGHA_00348	1.34e-109	lytE	-	-	M	-	-	-	NlpC P60 family
CIGNPGHA_00349	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
CIGNPGHA_00350	2.08e-101	-	-	-	L	-	-	-	Replication protein
CIGNPGHA_00352	1.47e-182	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
CIGNPGHA_00353	9.76e-229	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
CIGNPGHA_00354	5.11e-64	-	-	-	S	-	-	-	FRG
CIGNPGHA_00355	8.92e-11	-	-	-	S	-	-	-	Putative Holin-like Toxin (Hol-Tox)
CIGNPGHA_00356	2.07e-46	-	-	-	-	-	-	-	-
CIGNPGHA_00357	3.84e-191	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
CIGNPGHA_00358	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
CIGNPGHA_00359	3.59e-113	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
CIGNPGHA_00360	1.02e-219	-	-	-	L	-	-	-	Integrase core domain
CIGNPGHA_00361	6.85e-140	-	-	-	L	-	-	-	Bacterial dnaA protein
CIGNPGHA_00362	2.06e-29	-	-	-	K	-	-	-	DeoR C terminal sensor domain
CIGNPGHA_00363	1.99e-12	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
CIGNPGHA_00364	2.98e-35	-	3.2.1.4	GH5,GH9	M	ko:K01179	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	domain protein
CIGNPGHA_00365	4.7e-133	-	-	-	-	-	-	-	-
CIGNPGHA_00367	9.5e-98	icaB	-	-	G	-	-	-	Polysaccharide deacetylase
CIGNPGHA_00369	4.56e-87	-	-	-	S	-	-	-	Cupredoxin-like domain
CIGNPGHA_00370	0.0	copA	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
CIGNPGHA_00371	1.16e-203	morA	-	-	S	-	-	-	reductase
CIGNPGHA_00372	6.03e-289	dacA2	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
CIGNPGHA_00373	2.86e-102	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
CIGNPGHA_00374	0.0	copB	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
CIGNPGHA_00375	1.17e-214	-	-	-	EG	-	-	-	EamA-like transporter family
CIGNPGHA_00376	4.01e-153	-	-	-	S	-	-	-	Elongation factor G-binding protein, N-terminal
CIGNPGHA_00377	4.42e-136	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
CIGNPGHA_00378	1.4e-195	-	-	-	-	-	-	-	-
CIGNPGHA_00379	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
CIGNPGHA_00380	0.0	pacL1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
CIGNPGHA_00381	3.92e-110	-	-	-	K	-	-	-	MarR family
CIGNPGHA_00382	9.34e-130	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
CIGNPGHA_00383	6.2e-264	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
CIGNPGHA_00384	0.0	-	-	-	EM	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
CIGNPGHA_00385	9.6e-217	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
CIGNPGHA_00386	3.05e-90	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	AsnC family
CIGNPGHA_00387	5.52e-241	adhP	1.1.1.1	-	C	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
CIGNPGHA_00388	2.76e-288	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
CIGNPGHA_00389	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
CIGNPGHA_00390	1.75e-129	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
CIGNPGHA_00391	3.98e-151	-	-	-	-	-	-	-	-
CIGNPGHA_00392	1.12e-314	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
CIGNPGHA_00393	2.42e-127	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
CIGNPGHA_00394	6.75e-96	-	-	-	C	-	-	-	Flavodoxin
CIGNPGHA_00395	1.78e-285	fabV	1.3.1.44, 1.3.1.9	-	I	ko:K00209	ko00061,ko00650,ko01100,ko01120,ko01200,ko01212,map00061,map00650,map01100,map01120,map01200,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	NAD(P)H binding domain of trans-2-enoyl-CoA reductase
CIGNPGHA_00396	1.03e-238	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CIGNPGHA_00397	5.39e-194	-	-	-	S	-	-	-	Putative adhesin
CIGNPGHA_00398	2.1e-117	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
CIGNPGHA_00399	1.03e-70	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
CIGNPGHA_00400	4.83e-136	pncA	-	-	Q	-	-	-	Isochorismatase family
CIGNPGHA_00401	4.28e-270	srfJ1	3.2.1.45	GH30	M	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 30 family
CIGNPGHA_00402	2.39e-196	-	-	-	G	-	-	-	MFS/sugar transport protein
CIGNPGHA_00403	6.62e-307	lacZ3	3.2.1.23	-	G	ko:K01190,ko:K12308	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Beta-galactosidase trimerisation domain
CIGNPGHA_00404	6.57e-100	-	-	-	K	-	-	-	AraC-like ligand binding domain
CIGNPGHA_00405	7.48e-299	-	3.2.1.21, 3.2.1.52	GH3	G	ko:K01207,ko:K05349	ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501	ko00000,ko00001,ko00002,ko01000	Fibronectin type III-like domain
CIGNPGHA_00406	3.75e-209	-	-	-	G	-	-	-	Peptidase_C39 like family
CIGNPGHA_00407	1.96e-254	-	-	-	M	-	-	-	NlpC/P60 family
CIGNPGHA_00408	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CIGNPGHA_00409	3.75e-54	-	-	-	S	-	-	-	Pfam Methyltransferase
CIGNPGHA_00411	2.16e-122	cadD	-	-	P	-	-	-	Cadmium resistance transporter
CIGNPGHA_00412	7.39e-98	-	-	-	K	ko:K03827	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
CIGNPGHA_00413	4.37e-43	-	-	-	-	-	-	-	-
CIGNPGHA_00414	6.05e-225	-	-	-	EG	-	-	-	EamA-like transporter family
CIGNPGHA_00415	1.99e-58	-	-	-	L	ko:K07473	-	ko00000,ko02048	Addiction module antitoxin, RelB DinJ family
CIGNPGHA_00416	5.3e-110	-	-	-	-	-	-	-	-
CIGNPGHA_00417	1.03e-55	-	-	-	-	-	-	-	-
CIGNPGHA_00418	8.44e-201	dkgB	-	-	S	-	-	-	reductase
CIGNPGHA_00419	3.7e-94	-	-	-	EGP	-	-	-	Major Facilitator
CIGNPGHA_00420	3.58e-283	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
CIGNPGHA_00421	1.28e-172	XK27_00340	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
CIGNPGHA_00422	1.98e-214	ytbD	-	-	EGP	ko:K19577	-	ko00000,ko02000	Major Facilitator
CIGNPGHA_00423	8.67e-164	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
CIGNPGHA_00424	3.15e-229	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
CIGNPGHA_00425	5.66e-188	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
CIGNPGHA_00426	2.15e-153	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CIGNPGHA_00427	4.56e-120	-	-	-	V	-	-	-	VanZ like family
CIGNPGHA_00428	6.2e-114	ysaA	-	-	V	-	-	-	VanZ like family
CIGNPGHA_00429	2.37e-95	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
CIGNPGHA_00430	2.29e-113	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
CIGNPGHA_00431	2.42e-204	-	-	-	S	-	-	-	EDD domain protein, DegV family
CIGNPGHA_00432	3.15e-296	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
CIGNPGHA_00433	2.57e-251	npp	-	-	S	-	-	-	type I phosphodiesterase nucleotide pyrophosphatase
CIGNPGHA_00434	2.12e-92	-	-	-	K	-	-	-	Transcriptional regulator
CIGNPGHA_00435	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
CIGNPGHA_00436	0.0	pyrAB2	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
CIGNPGHA_00437	3.3e-260	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
CIGNPGHA_00438	6.85e-115	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CIGNPGHA_00439	1.8e-220	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
CIGNPGHA_00440	9.45e-104	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CIGNPGHA_00441	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
CIGNPGHA_00442	1.53e-74	esbA	-	-	S	-	-	-	Family of unknown function (DUF5322)
CIGNPGHA_00443	1.59e-90	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
CIGNPGHA_00444	9.19e-266	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	FAD dependent oxidoreductase
CIGNPGHA_00445	1.79e-144	XK27_02070	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
CIGNPGHA_00446	1.5e-112	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
CIGNPGHA_00447	4.85e-158	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
CIGNPGHA_00448	1.16e-72	-	-	-	-	-	-	-	-
CIGNPGHA_00449	5.74e-107	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
CIGNPGHA_00450	1.17e-38	-	-	-	-	-	-	-	-
CIGNPGHA_00451	1.06e-311	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
CIGNPGHA_00452	6.93e-88	-	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
CIGNPGHA_00453	1.98e-279	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
CIGNPGHA_00455	7e-52	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
CIGNPGHA_00456	1.96e-138	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
CIGNPGHA_00457	5.76e-146	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
CIGNPGHA_00458	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
CIGNPGHA_00459	7.67e-80	-	-	-	P	-	-	-	Rhodanese Homology Domain
CIGNPGHA_00460	2.51e-115	yetL	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
CIGNPGHA_00461	1.33e-159	dnaD	-	-	L	ko:K02086	-	ko00000	Replication initiation and membrane attachment
CIGNPGHA_00462	2.09e-267	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
CIGNPGHA_00463	1.08e-113	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
CIGNPGHA_00464	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
CIGNPGHA_00465	1.6e-218	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
CIGNPGHA_00466	3.64e-224	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
CIGNPGHA_00467	4.33e-260	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
CIGNPGHA_00468	5.06e-237	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
CIGNPGHA_00469	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
CIGNPGHA_00470	8.09e-194	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
CIGNPGHA_00471	4.61e-272	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
CIGNPGHA_00472	1.2e-106	-	-	-	-	-	-	-	-
CIGNPGHA_00473	9.37e-133	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
CIGNPGHA_00474	5.15e-247	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
CIGNPGHA_00476	4.07e-92	-	-	-	T	-	-	-	Universal stress protein family
CIGNPGHA_00477	6.58e-165	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
CIGNPGHA_00478	5.29e-86	-	-	-	L	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
CIGNPGHA_00479	5.04e-75	-	-	-	-	-	-	-	-
CIGNPGHA_00480	7.13e-17	-	-	-	S	-	-	-	Protein of unknown function (DUF3278)
CIGNPGHA_00481	1.81e-84	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
CIGNPGHA_00482	2.53e-173	cat	2.3.1.28	-	V	ko:K19271	-	br01600,ko00000,ko01000,ko01504	Chloramphenicol acetyltransferase
CIGNPGHA_00483	3.71e-281	-	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
CIGNPGHA_00484	2.96e-216	-	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
CIGNPGHA_00485	1.8e-124	-	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC transporter permease
CIGNPGHA_00486	0.0	-	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
CIGNPGHA_00487	4.31e-149	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
CIGNPGHA_00488	5.93e-156	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CIGNPGHA_00489	4.78e-79	-	-	-	-	-	-	-	-
CIGNPGHA_00490	1.59e-10	-	-	-	-	-	-	-	-
CIGNPGHA_00492	3.18e-58	-	-	-	-	-	-	-	-
CIGNPGHA_00493	2.69e-276	-	-	-	-	-	-	-	-
CIGNPGHA_00494	1.3e-239	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
CIGNPGHA_00495	9.57e-36	-	-	-	-	-	-	-	-
CIGNPGHA_00496	1.82e-316	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
CIGNPGHA_00497	1.8e-215	natA	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
CIGNPGHA_00498	3.11e-271	natB	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
CIGNPGHA_00500	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
CIGNPGHA_00501	7.25e-206	yitS	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
CIGNPGHA_00502	1.25e-196	-	-	-	C	-	-	-	Aldo keto reductase
CIGNPGHA_00503	4.07e-85	-	-	-	S	-	-	-	Protein of unknown function (DUF1722)
CIGNPGHA_00504	5.58e-91	yqeB	-	-	S	-	-	-	Pyrimidine dimer DNA glycosylase
CIGNPGHA_00505	0.0	gadB	4.1.1.15, 4.1.2.27	-	E	ko:K01580,ko:K01634	ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940	ko00000,ko00001,ko00002,ko01000	Belongs to the group II decarboxylase family
CIGNPGHA_00506	4.67e-163	rcfB	-	-	K	-	-	-	Crp-like helix-turn-helix domain
CIGNPGHA_00507	1.71e-301	larA	5.1.2.1	-	S	ko:K22373	ko00620,map00620	ko00000,ko00001,ko01000	Domain of unknown function (DUF2088)
CIGNPGHA_00508	1.13e-171	larB	-	-	S	ko:K06898	-	ko00000	AIR carboxylase
CIGNPGHA_00509	2.55e-288	larC	4.99.1.12	-	S	ko:K09121	-	ko00000,ko01000	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
CIGNPGHA_00510	2.05e-191	larE	-	-	S	ko:K06864	-	ko00000	NAD synthase
CIGNPGHA_00511	2.21e-160	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
CIGNPGHA_00512	8.66e-229	-	-	-	U	ko:K07241	-	ko00000,ko02000	High-affinity nickel-transport protein
CIGNPGHA_00513	2.9e-53	yfhR3	-	-	S	ko:K06889	-	ko00000	Serine hydrolase (FSH1)
CIGNPGHA_00514	1.95e-41	yfhR3	-	-	S	ko:K06889	-	ko00000	Serine hydrolase (FSH1)
CIGNPGHA_00515	8.39e-54	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
CIGNPGHA_00516	4.06e-267	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
CIGNPGHA_00517	4.82e-188	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
CIGNPGHA_00518	1.21e-173	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
CIGNPGHA_00519	1.15e-259	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
CIGNPGHA_00520	8.38e-190	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
CIGNPGHA_00521	4.95e-192	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
CIGNPGHA_00522	4.2e-215	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
CIGNPGHA_00523	1.19e-199	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
CIGNPGHA_00524	2.15e-75	-	-	-	-	-	-	-	-
CIGNPGHA_00525	1.91e-42	-	-	-	-	-	-	-	-
CIGNPGHA_00526	2.14e-57	-	-	-	-	-	-	-	-
CIGNPGHA_00527	0.0	uvrB3	3.1.12.1	-	KL	ko:K07464	-	ko00000,ko01000,ko02048	DEAD_2
CIGNPGHA_00528	6.36e-162	-	-	-	-	-	-	-	-
CIGNPGHA_00529	2.22e-229	-	-	-	-	-	-	-	-
CIGNPGHA_00530	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
CIGNPGHA_00531	5.22e-270	-	-	-	KLT	-	-	-	Protein kinase domain
CIGNPGHA_00532	1.05e-97	-	-	-	L	-	-	-	Transposase DDE domain
CIGNPGHA_00533	9.56e-89	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
CIGNPGHA_00535	4.49e-74	-	-	-	L	-	-	-	Transposase DDE domain
CIGNPGHA_00536	1.85e-73	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
CIGNPGHA_00540	2.17e-152	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
CIGNPGHA_00541	3.24e-57	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
CIGNPGHA_00542	4.32e-296	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CIGNPGHA_00544	8.25e-168	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
CIGNPGHA_00545	2.02e-157	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Belongs to the alpha-acetolactate decarboxylase family
CIGNPGHA_00546	0.0	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
CIGNPGHA_00547	7.75e-94	-	-	-	K	-	-	-	Transcriptional regulator
CIGNPGHA_00548	7.74e-299	-	-	-	-	-	-	-	-
CIGNPGHA_00549	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
CIGNPGHA_00550	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
CIGNPGHA_00551	3.8e-78	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
CIGNPGHA_00552	1.22e-102	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
CIGNPGHA_00553	2.61e-199	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	biotin lipoate A B protein ligase
CIGNPGHA_00554	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
CIGNPGHA_00555	1.89e-188	yxeH	-	-	S	-	-	-	hydrolase
CIGNPGHA_00556	0.0	xpkA	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
CIGNPGHA_00557	5.42e-169	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
CIGNPGHA_00558	1.15e-94	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
CIGNPGHA_00559	9e-74	-	-	-	S	-	-	-	Domain of unknown function (DUF3899)
CIGNPGHA_00560	2.8e-229	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CIGNPGHA_00561	7.66e-308	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CIGNPGHA_00562	1.69e-184	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
CIGNPGHA_00565	2.09e-173	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
CIGNPGHA_00566	4.16e-168	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
CIGNPGHA_00567	2.66e-218	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
CIGNPGHA_00568	1.94e-206	-	-	-	S	ko:K06889	-	ko00000	Prolyl oligopeptidase family
CIGNPGHA_00570	2.09e-07	-	-	-	-	-	-	-	-
CIGNPGHA_00571	5.74e-211	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
CIGNPGHA_00572	1.78e-124	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
CIGNPGHA_00573	1.07e-200	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
CIGNPGHA_00574	2.28e-272	xylR	-	-	GK	-	-	-	ROK family
CIGNPGHA_00575	0.0	xylP	-	-	G	ko:K03292	-	ko00000	MFS/sugar transport protein
CIGNPGHA_00576	0.0	yicI	3.2.1.177	GH31	G	ko:K01811	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 31 family
CIGNPGHA_00577	2.84e-116	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
CIGNPGHA_00578	2.02e-52	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
CIGNPGHA_00579	3.94e-220	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
CIGNPGHA_00580	3.71e-193	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CIGNPGHA_00581	9.43e-154	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
CIGNPGHA_00582	9.83e-148	yjbH	-	-	Q	-	-	-	Thioredoxin
CIGNPGHA_00583	1.24e-201	degV1	-	-	S	-	-	-	DegV family
CIGNPGHA_00584	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
CIGNPGHA_00585	6.04e-250	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
CIGNPGHA_00586	7.82e-160	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
CIGNPGHA_00587	1.57e-192	ytmP	-	-	M	-	-	-	Choline/ethanolamine kinase
CIGNPGHA_00588	5.74e-284	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
CIGNPGHA_00589	2.85e-173	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
CIGNPGHA_00590	5.29e-109	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
CIGNPGHA_00591	1.78e-67	-	-	-	-	-	-	-	-
CIGNPGHA_00592	8.85e-195	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
CIGNPGHA_00593	4.89e-238	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
CIGNPGHA_00594	0.0	yhaN	-	-	L	-	-	-	AAA domain
CIGNPGHA_00595	3.27e-297	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
CIGNPGHA_00596	2.44e-71	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
CIGNPGHA_00597	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
CIGNPGHA_00598	5.9e-103	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
CIGNPGHA_00599	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
CIGNPGHA_00601	3.49e-24	-	-	-	-	-	-	-	-
CIGNPGHA_00602	1.53e-305	-	3.2.1.96, 3.5.1.28	GH73	M	ko:K01227,ko:K01447,ko:K13714,ko:K13731	ko00511,ko05100,map00511,map05100	ko00000,ko00001,ko01000	N-acetylmuramoyl-L-alanine amidase
CIGNPGHA_00603	2.14e-127	ywjB	-	-	H	-	-	-	RibD C-terminal domain
CIGNPGHA_00604	6.5e-71	-	-	-	S	-	-	-	Protein of unknown function (DUF1516)
CIGNPGHA_00605	9.43e-109	-	-	-	G	ko:K03483	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
CIGNPGHA_00606	4.43e-275	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CIGNPGHA_00607	6.51e-314	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CIGNPGHA_00608	3.37e-240	ulaA	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
CIGNPGHA_00609	9.95e-32	ulaB	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase system galactitol-specific IIB component
CIGNPGHA_00610	1e-42	-	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
CIGNPGHA_00611	2.13e-168	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
CIGNPGHA_00612	0.0	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
CIGNPGHA_00613	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
CIGNPGHA_00614	3.63e-153	rcfA	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
CIGNPGHA_00615	0.0	-	-	-	E	-	-	-	Peptidase family C69
CIGNPGHA_00616	1.18e-50	-	-	-	-	-	-	-	-
CIGNPGHA_00617	0.0	-	-	-	-	-	-	-	-
CIGNPGHA_00618	2.94e-49	inlJ	-	-	M	-	-	-	MucBP domain
CIGNPGHA_00621	1.65e-208	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
CIGNPGHA_00622	6.57e-11	-	-	-	K	-	-	-	Transcriptional regulator
CIGNPGHA_00623	4.89e-53	-	-	-	K	-	-	-	Transcriptional regulator
CIGNPGHA_00624	2.29e-252	adhB	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
CIGNPGHA_00625	9.1e-65	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2316)
CIGNPGHA_00626	6.56e-87	-	-	-	K	ko:K18909	-	ko00000,ko00002,ko01504,ko03000	MarR family
CIGNPGHA_00627	1.17e-51	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
CIGNPGHA_00628	6.28e-125	-	-	-	GM	-	-	-	Male sterility protein
CIGNPGHA_00629	2.6e-232	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
CIGNPGHA_00630	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
CIGNPGHA_00631	1.26e-36	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Major Facilitator Superfamily
CIGNPGHA_00632	2.16e-247	nhaK	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
CIGNPGHA_00633	1.69e-77	-	-	-	S	-	-	-	Belongs to the HesB IscA family
CIGNPGHA_00634	1.76e-225	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
CIGNPGHA_00635	7.75e-145	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
CIGNPGHA_00636	1.51e-248	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
CIGNPGHA_00637	1.36e-157	ybhF_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
CIGNPGHA_00639	6.64e-162	-	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	N-acetylmuramoyl-L-alanine amidase
CIGNPGHA_00640	1.35e-55	-	-	-	S	-	-	-	Mor transcription activator family
CIGNPGHA_00641	6.09e-53	-	-	-	S	-	-	-	Mor transcription activator family
CIGNPGHA_00642	8.26e-92	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CIGNPGHA_00643	5.12e-132	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
CIGNPGHA_00644	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
CIGNPGHA_00645	6.9e-254	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CIGNPGHA_00646	1.36e-79	-	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	6-pyruvoyl tetrahydropterin synthase
CIGNPGHA_00647	8.9e-269	icaA	-	-	M	-	-	-	Glycosyl transferase family group 2
CIGNPGHA_00648	3.32e-135	-	-	-	-	-	-	-	-
CIGNPGHA_00649	2.31e-163	-	-	-	-	-	-	-	-
CIGNPGHA_00650	1.88e-76	-	-	-	-	-	-	-	-
CIGNPGHA_00651	6.21e-39	yozG	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
CIGNPGHA_00652	8.9e-61	-	-	-	S	-	-	-	Protein of unknown function (DUF2975)
CIGNPGHA_00653	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CIGNPGHA_00654	1.22e-36	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
CIGNPGHA_00655	2.96e-198	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CIGNPGHA_00656	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
CIGNPGHA_00657	0.0	potE	-	-	E	-	-	-	Amino Acid
CIGNPGHA_00658	5.86e-56	-	-	-	S	-	-	-	protein with an alpha beta hydrolase fold
CIGNPGHA_00659	8.76e-175	-	-	-	K	-	-	-	Helix-turn-helix
CIGNPGHA_00660	5.99e-45	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
CIGNPGHA_00661	1.01e-58	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain
CIGNPGHA_00662	6.6e-86	-	-	-	-	-	-	-	-
CIGNPGHA_00663	1.56e-131	-	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
CIGNPGHA_00664	2.03e-118	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
CIGNPGHA_00665	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
CIGNPGHA_00666	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
CIGNPGHA_00667	3.05e-121	-	-	-	K	-	-	-	acetyltransferase
CIGNPGHA_00668	3.17e-149	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
CIGNPGHA_00670	3.26e-226	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
CIGNPGHA_00671	1.16e-213	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
CIGNPGHA_00672	2.14e-234	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
CIGNPGHA_00673	2.41e-199	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CIGNPGHA_00674	4.08e-219	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CIGNPGHA_00675	7.21e-50	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
CIGNPGHA_00676	5.88e-72	-	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain protein
CIGNPGHA_00677	1.68e-155	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
CIGNPGHA_00678	6.12e-180	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
CIGNPGHA_00679	5.46e-194	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
CIGNPGHA_00680	1.68e-198	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
CIGNPGHA_00681	8.95e-201	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
CIGNPGHA_00682	6.18e-205	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
CIGNPGHA_00683	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
CIGNPGHA_00684	2.49e-166	phoP	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
CIGNPGHA_00685	5.08e-284	minJ	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
CIGNPGHA_00686	9.3e-236	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CIGNPGHA_00687	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
CIGNPGHA_00688	3.5e-126	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CIGNPGHA_00689	5.9e-162	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
CIGNPGHA_00690	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
CIGNPGHA_00691	2.39e-147	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
CIGNPGHA_00692	6.19e-243	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
CIGNPGHA_00693	1.17e-91	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	LrgA family
CIGNPGHA_00694	1.8e-180	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	LrgB-like family
CIGNPGHA_00695	0.0	ydaO	-	-	E	-	-	-	amino acid
CIGNPGHA_00696	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
CIGNPGHA_00697	4.49e-60	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CIGNPGHA_00698	3.84e-145	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CIGNPGHA_00699	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
CIGNPGHA_00700	3.61e-61	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
CIGNPGHA_00701	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
CIGNPGHA_00702	3.96e-49	ykuJ	-	-	S	-	-	-	Protein of unknown function (DUF1797)
CIGNPGHA_00703	1.83e-234	mprF	-	-	S	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CIGNPGHA_00704	9.58e-244	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
CIGNPGHA_00705	2e-285	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
CIGNPGHA_00706	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CIGNPGHA_00707	2.6e-54	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
CIGNPGHA_00708	3.61e-42	-	-	-	-	-	-	-	-
CIGNPGHA_00709	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
CIGNPGHA_00710	1.12e-272	-	-	-	G	-	-	-	MucBP domain
CIGNPGHA_00711	0.0	pacL3	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
CIGNPGHA_00712	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
CIGNPGHA_00713	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
CIGNPGHA_00714	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
CIGNPGHA_00715	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CIGNPGHA_00716	3.64e-117	-	-	-	-	-	-	-	-
CIGNPGHA_00717	0.0	tagF	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	glycerophosphotransferase
CIGNPGHA_00718	1.06e-201	-	-	-	-	-	-	-	-
CIGNPGHA_00719	2.51e-98	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Glycerol-3-phosphate cytidylyltransferase
CIGNPGHA_00720	2.66e-252	yueF	-	-	S	-	-	-	AI-2E family transporter
CIGNPGHA_00721	1.5e-140	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
CIGNPGHA_00722	2.15e-52	-	-	-	S	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
CIGNPGHA_00723	1.11e-282	pbpX2	-	-	V	-	-	-	Beta-lactamase
CIGNPGHA_00724	8.69e-187	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
CIGNPGHA_00725	2.17e-102	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
CIGNPGHA_00726	4.48e-203	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
CIGNPGHA_00727	1.3e-201	-	-	-	S	-	-	-	Nuclease-related domain
CIGNPGHA_00728	1.05e-272	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
CIGNPGHA_00729	6.25e-202	csbB	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	Glycosyltransferase like family 2
CIGNPGHA_00730	2.22e-296	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
CIGNPGHA_00731	7.84e-101	-	-	-	T	-	-	-	Universal stress protein family
CIGNPGHA_00734	2.15e-298	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
CIGNPGHA_00735	9.54e-241	mocA	-	-	S	-	-	-	Oxidoreductase
CIGNPGHA_00736	2.89e-84	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
CIGNPGHA_00737	5.71e-190	lys	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
CIGNPGHA_00738	8.34e-195	gntR	-	-	K	-	-	-	rpiR family
CIGNPGHA_00739	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
CIGNPGHA_00740	4.42e-292	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
CIGNPGHA_00741	2.1e-304	-	-	-	E	ko:K03294	-	ko00000	amino acid
CIGNPGHA_00742	9.26e-317	fucP	-	-	G	ko:K02429	-	ko00000,ko02000	Major Facilitator Superfamily
CIGNPGHA_00743	5.83e-87	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
CIGNPGHA_00744	0.0	gshA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
CIGNPGHA_00745	1.09e-307	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	pyrimidine-nucleoside phosphorylase
CIGNPGHA_00746	6.79e-222	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	sugar-binding domain protein
CIGNPGHA_00747	1.23e-166	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
CIGNPGHA_00748	2.2e-295	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CIGNPGHA_00749	1.05e-155	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CIGNPGHA_00750	1.27e-50	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
CIGNPGHA_00751	1.06e-76	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
CIGNPGHA_00752	3.98e-185	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Pfam:Y_phosphatase3C
CIGNPGHA_00753	1.87e-248	namA	-	-	C	-	-	-	Oxidoreductase
CIGNPGHA_00754	1.47e-72	-	-	-	E	ko:K04031	-	ko00000	BMC
CIGNPGHA_00755	1.64e-281	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CIGNPGHA_00756	1.31e-269	pduQ	-	-	C	ko:K13921	ko00640,map00640	ko00000,ko00001	Iron-containing alcohol dehydrogenase
CIGNPGHA_00757	0.0	pduP	1.2.1.87	-	C	ko:K13922	ko00640,map00640	ko00000,ko00001,ko01000	Aldehyde dehydrogenase family
CIGNPGHA_00758	2.89e-105	pduO	-	-	S	-	-	-	Haem-degrading
CIGNPGHA_00759	7.33e-135	-	-	-	S	-	-	-	Cobalamin adenosyltransferase
CIGNPGHA_00760	3.12e-56	pduN	-	-	CQ	ko:K04028	-	ko00000	Ethanolamine utilisation protein EutN/carboxysome
CIGNPGHA_00761	1.51e-116	-	-	-	S	-	-	-	Putative propanediol utilisation
CIGNPGHA_00762	4.89e-146	pduL	2.3.1.222	-	Q	ko:K13923	ko00640,map00640	ko00000,ko00001,ko01000	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate
CIGNPGHA_00763	3.38e-56	pduJ	-	-	CQ	-	-	-	BMC
CIGNPGHA_00764	1.13e-108	-	-	-	CQ	-	-	-	BMC
CIGNPGHA_00765	2.32e-75	pduH	-	-	S	-	-	-	Dehydratase medium subunit
CIGNPGHA_00766	0.0	pduG	-	-	D	-	-	-	Diol dehydratase reactivase ATPase-like domain
CIGNPGHA_00767	2.23e-119	pduE	4.2.1.28	-	Q	ko:K13920	ko00640,map00640	ko00000,ko00001,ko01000	Dehydratase small subunit
CIGNPGHA_00768	2.9e-167	pduD	4.2.1.28	-	Q	ko:K13919	ko00640,map00640	ko00000,ko00001,ko01000	Dehydratase medium subunit
CIGNPGHA_00769	0.0	pduC	4.2.1.28	-	Q	ko:K01699	ko00640,map00640	ko00000,ko00001,ko01000	Dehydratase large subunit
CIGNPGHA_00770	1.56e-166	pduB	-	-	E	-	-	-	BMC
CIGNPGHA_00771	1.47e-55	-	-	-	CQ	-	-	-	BMC
CIGNPGHA_00772	5.72e-263	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
CIGNPGHA_00773	4.82e-164	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
CIGNPGHA_00774	3.37e-56	eutP	-	-	E	ko:K04029	-	ko00000	Ethanolamine utilisation - propanediol utilisation
CIGNPGHA_00775	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CIGNPGHA_00776	1.57e-237	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
CIGNPGHA_00777	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CIGNPGHA_00778	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
CIGNPGHA_00779	4.8e-66	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CIGNPGHA_00780	1.33e-257	camS	-	-	S	-	-	-	sex pheromone
CIGNPGHA_00781	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CIGNPGHA_00782	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
CIGNPGHA_00783	2.47e-274	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CIGNPGHA_00784	1.86e-128	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
CIGNPGHA_00785	2.14e-205	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
CIGNPGHA_00786	5e-227	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
CIGNPGHA_00787	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CIGNPGHA_00788	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
CIGNPGHA_00789	6.5e-224	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
CIGNPGHA_00790	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
CIGNPGHA_00791	4.52e-47	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
CIGNPGHA_00792	8.89e-218	-	-	-	-	-	-	-	-
CIGNPGHA_00793	8.35e-175	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
CIGNPGHA_00794	1.29e-194	glnH	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
CIGNPGHA_00795	1.5e-142	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
CIGNPGHA_00796	4.59e-140	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
CIGNPGHA_00797	2.8e-295	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CIGNPGHA_00798	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
CIGNPGHA_00799	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
CIGNPGHA_00800	7.11e-203	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CIGNPGHA_00801	1.11e-238	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CIGNPGHA_00802	1.24e-259	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
CIGNPGHA_00803	3.27e-229	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
CIGNPGHA_00804	2.61e-154	pgm3	-	-	G	-	-	-	phosphoglycerate mutase
CIGNPGHA_00805	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
CIGNPGHA_00806	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
CIGNPGHA_00807	2.39e-225	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
CIGNPGHA_00808	6.78e-136	-	-	-	K	-	-	-	acetyltransferase
CIGNPGHA_00809	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
CIGNPGHA_00810	3.9e-109	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
CIGNPGHA_00811	3.11e-48	-	-	-	T	-	-	-	PemK-like, MazF-like toxin of type II toxin-antitoxin system
CIGNPGHA_00814	1.1e-62	-	-	-	E	-	-	-	IrrE N-terminal-like domain
CIGNPGHA_00815	1.63e-48	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
CIGNPGHA_00816	2.13e-10	-	-	-	K	-	-	-	sequence-specific DNA binding
CIGNPGHA_00828	2.81e-84	-	-	-	L	ko:K07455	-	ko00000,ko03400	RecT family
CIGNPGHA_00829	3.38e-105	pi112	-	-	L	-	-	-	PDDEXK-like domain of unknown function (DUF3799)
CIGNPGHA_00831	2.94e-68	-	-	-	K	ko:K07741	-	ko00000	AntA/AntB antirepressor
CIGNPGHA_00832	1.55e-54	-	-	-	S	-	-	-	Endodeoxyribonuclease RusA
CIGNPGHA_00835	1.99e-42	-	-	-	-	-	-	-	-
CIGNPGHA_00836	2.96e-72	-	-	-	-	-	-	-	-
CIGNPGHA_00838	1.58e-227	-	-	-	S	-	-	-	Baseplate J-like protein
CIGNPGHA_00839	2.95e-95	-	-	-	-	-	-	-	-
CIGNPGHA_00840	1.42e-218	pmrB	-	-	EGP	-	-	-	Major Facilitator Superfamily
CIGNPGHA_00841	2.24e-92	-	-	-	S	-	-	-	COG NOG18757 non supervised orthologous group
CIGNPGHA_00843	1.96e-293	-	-	-	EK	-	-	-	Aminotransferase, class I
CIGNPGHA_00844	0.0	fusA1	-	-	J	-	-	-	elongation factor G
CIGNPGHA_00845	1.13e-164	-	-	-	F	-	-	-	glutamine amidotransferase
CIGNPGHA_00846	1.28e-16	yhaZ	-	-	L	-	-	-	DNA alkylation repair enzyme
CIGNPGHA_00847	2.81e-159	yhaZ	-	-	L	-	-	-	DNA alkylation repair enzyme
CIGNPGHA_00848	2.48e-159	-	-	-	K	-	-	-	UTRA
CIGNPGHA_00849	5.75e-242	-	-	-	O	-	-	-	ADP-ribosylglycohydrolase
CIGNPGHA_00850	0.0	-	-	-	F	ko:K03457	-	ko00000	Belongs to the purine-cytosine permease (2.A.39) family
CIGNPGHA_00851	1.31e-210	-	-	-	G	-	-	-	Belongs to the carbohydrate kinase PfkB family
CIGNPGHA_00852	1.28e-225	pepI	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
CIGNPGHA_00853	5.23e-170	-	-	-	S	-	-	-	Protein of unknown function
CIGNPGHA_00854	1.06e-226	-	-	-	EGP	ko:K08196	-	ko00000,ko02000	Major Facilitator
CIGNPGHA_00855	3.54e-24	-	-	-	EGP	ko:K08196	-	ko00000,ko02000	Major Facilitator
CIGNPGHA_00856	6.47e-155	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
CIGNPGHA_00857	8.43e-144	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CIGNPGHA_00858	2.8e-173	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
CIGNPGHA_00859	0.0	-	3.2.1.45	GH30	G	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	ko00000,ko00001,ko01000	Glycosyl hydrolase family 30 TIM-barrel domain
CIGNPGHA_00860	1.24e-201	-	-	-	K	-	-	-	Transcriptional regulator
CIGNPGHA_00861	4.68e-09	-	-	-	S	-	-	-	Protein of unknown function (DUF2992)
CIGNPGHA_00862	7.18e-43	-	-	-	S	-	-	-	Transglycosylase associated protein
CIGNPGHA_00863	2.5e-52	-	-	-	-	-	-	-	-
CIGNPGHA_00864	0.0	abfA	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	Alpha-L-arabinofuranosidase C-terminus
CIGNPGHA_00865	2.5e-201	-	-	-	EG	-	-	-	EamA-like transporter family
CIGNPGHA_00866	7.56e-36	-	-	-	-	-	-	-	-
CIGNPGHA_00867	2.54e-266	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
CIGNPGHA_00868	9.7e-252	ptcA	2.1.3.6	-	E	ko:K13252	-	ko00000,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CIGNPGHA_00869	3.12e-308	aguD	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	Amino Acid
CIGNPGHA_00870	8.96e-277	aguA	3.5.3.12	-	E	ko:K10536	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	agmatine deiminase
CIGNPGHA_00871	2.85e-216	arcC	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	Belongs to the carbamate kinase family
CIGNPGHA_00872	1.01e-276	aguA2	3.5.3.12	-	E	ko:K10536	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	agmatine deiminase
CIGNPGHA_00873	5.05e-192	-	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
CIGNPGHA_00874	3.19e-208	mleR	-	-	K	-	-	-	LysR family
CIGNPGHA_00875	0.0	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
CIGNPGHA_00876	4.7e-215	mleP2	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
CIGNPGHA_00877	3.2e-107	thiW	-	-	S	-	-	-	Thiamine-precursor transporter protein (ThiW)
CIGNPGHA_00878	5.86e-294	-	-	-	V	-	-	-	Beta-lactamase
CIGNPGHA_00879	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
CIGNPGHA_00881	1.63e-163	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CIGNPGHA_00882	1.42e-74	-	-	-	-	-	-	-	-
CIGNPGHA_00883	2.6e-129	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
CIGNPGHA_00884	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CIGNPGHA_00885	3e-272	yacL	-	-	S	-	-	-	domain protein
CIGNPGHA_00886	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CIGNPGHA_00887	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
CIGNPGHA_00888	7.28e-92	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CIGNPGHA_00889	4.28e-177	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CIGNPGHA_00890	7.3e-117	yacP	-	-	S	ko:K06962	-	ko00000	YacP-like NYN domain
CIGNPGHA_00891	2.97e-122	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Sigma-70 region 2
CIGNPGHA_00892	3.64e-34	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
CIGNPGHA_00893	1.61e-127	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
CIGNPGHA_00894	4.14e-94	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CIGNPGHA_00895	1.75e-160	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
CIGNPGHA_00896	3.73e-110	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CIGNPGHA_00897	7.9e-74	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
CIGNPGHA_00898	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CIGNPGHA_00899	7.64e-142	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
CIGNPGHA_00900	1.08e-215	-	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase
CIGNPGHA_00901	4.42e-249	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CIGNPGHA_00902	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CIGNPGHA_00903	9.51e-51	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
CIGNPGHA_00904	3.89e-145	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
CIGNPGHA_00905	1.09e-123	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
CIGNPGHA_00906	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CIGNPGHA_00907	9.59e-58	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CIGNPGHA_00908	1.31e-141	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CIGNPGHA_00909	2.48e-52	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
CIGNPGHA_00910	7.16e-141	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CIGNPGHA_00911	5.88e-72	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
CIGNPGHA_00912	1.04e-225	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
CIGNPGHA_00913	3.21e-62	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
CIGNPGHA_00914	1.68e-201	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CIGNPGHA_00915	1.15e-181	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
CIGNPGHA_00916	7.6e-159	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
CIGNPGHA_00917	1.65e-141	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
CIGNPGHA_00918	8.28e-249	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CIGNPGHA_00919	8.39e-159	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CIGNPGHA_00920	5.41e-231	-	-	-	EG	-	-	-	EamA-like transporter family
CIGNPGHA_00921	5.71e-212	mleP2	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
CIGNPGHA_00922	3.7e-259	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
CIGNPGHA_00923	4.58e-217	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
CIGNPGHA_00924	0.0	XK27_06930	-	-	V	ko:K01421	-	ko00000	domain protein
CIGNPGHA_00925	2.02e-131	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
CIGNPGHA_00926	3.3e-152	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
CIGNPGHA_00927	4.82e-211	-	-	-	T	-	-	-	diguanylate cyclase
CIGNPGHA_00928	1.94e-226	ydbI	-	-	K	-	-	-	AI-2E family transporter
CIGNPGHA_00929	2.4e-193	manN	-	-	G	ko:K02796,ko:K02815	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
CIGNPGHA_00930	4.4e-173	manM	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
CIGNPGHA_00931	8.55e-79	manX	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
CIGNPGHA_00932	5.33e-71	levD	2.7.1.191, 2.7.1.202	-	G	ko:K02793,ko:K02794,ko:K11194	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
CIGNPGHA_00933	3.3e-137	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant
CIGNPGHA_00934	3.81e-310	dinF	-	-	V	-	-	-	MatE
CIGNPGHA_00935	6.05e-98	-	-	-	K	-	-	-	MarR family
CIGNPGHA_00936	3.74e-130	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
CIGNPGHA_00937	4.99e-81	-	-	-	K	-	-	-	transcriptional regulator
CIGNPGHA_00938	1.21e-156	-	-	-	S	-	-	-	Alpha/beta hydrolase family
CIGNPGHA_00939	5.63e-191	-	4.1.1.52	-	S	ko:K22213	-	ko00000,ko01000	Amidohydrolase
CIGNPGHA_00941	3.42e-202	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
CIGNPGHA_00942	1.75e-115	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
CIGNPGHA_00943	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
CIGNPGHA_00944	3e-93	-	-	-	-	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	-
CIGNPGHA_00945	7.76e-195	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
CIGNPGHA_00946	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CIGNPGHA_00947	1.5e-177	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
CIGNPGHA_00948	9.21e-120	yfbM	-	-	K	-	-	-	FR47-like protein
CIGNPGHA_00949	2.79e-162	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
CIGNPGHA_00950	1.56e-276	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CIGNPGHA_00951	1.15e-171	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CIGNPGHA_00954	2.28e-181	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
CIGNPGHA_00955	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
CIGNPGHA_00956	4.54e-70	-	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
CIGNPGHA_00958	3.04e-233	ydhF	-	-	S	-	-	-	Aldo keto reductase
CIGNPGHA_00959	1.14e-175	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
CIGNPGHA_00960	0.0	-	-	-	Q	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
CIGNPGHA_00961	5.55e-79	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
CIGNPGHA_00962	3.22e-90	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
CIGNPGHA_00963	3.87e-263	-	-	-	M	-	-	-	Collagen binding domain
CIGNPGHA_00964	0.0	cadA	-	-	P	-	-	-	P-type ATPase
CIGNPGHA_00965	2.47e-153	-	-	-	S	-	-	-	SNARE associated Golgi protein
CIGNPGHA_00966	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
CIGNPGHA_00967	2.02e-69	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
CIGNPGHA_00968	2.63e-128	cadD	-	-	P	-	-	-	Cadmium resistance transporter
CIGNPGHA_00969	3.87e-208	-	-	-	S	-	-	-	Conserved hypothetical protein 698
CIGNPGHA_00970	2.89e-195	-	-	-	K	-	-	-	LysR substrate binding domain
CIGNPGHA_00971	2.83e-190	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	transporter
CIGNPGHA_00972	3.08e-52	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	transporter
CIGNPGHA_00973	4.15e-96	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
CIGNPGHA_00974	8.24e-87	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
CIGNPGHA_00975	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
CIGNPGHA_00976	9.86e-210	oroP	-	-	S	ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Putative inner membrane exporter, YdcZ
CIGNPGHA_00977	2.5e-230	iunH5	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	inosine-uridine preferring nucleoside hydrolase
CIGNPGHA_00978	7.27e-42	-	-	-	-	-	-	-	-
CIGNPGHA_00979	0.0	-	2.8.2.22	-	M	ko:K01023	-	ko00000,ko01000	Arylsulfotransferase Ig-like domain
CIGNPGHA_00980	3.69e-169	-	-	-	S	-	-	-	B3/4 domain
CIGNPGHA_00981	6.56e-164	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
CIGNPGHA_00982	2.63e-82	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
CIGNPGHA_00983	2.52e-206	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
CIGNPGHA_00984	4.11e-224	-	-	-	-	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	-
CIGNPGHA_00985	1.94e-246	-	-	-	KT	ko:K02647	-	ko00000,ko03000	Putative sugar diacid recognition
CIGNPGHA_00986	6.98e-273	yojA	-	-	EG	ko:K03299	-	ko00000,ko02000	GntP family permease
CIGNPGHA_00987	3.08e-264	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
CIGNPGHA_00988	4.84e-242	nhaP4	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
CIGNPGHA_00989	0.0	ydbT	-	-	S	ko:K08981	-	ko00000	Bacterial PH domain
CIGNPGHA_00990	9.36e-111	ydbS	-	-	S	ko:K09167	-	ko00000	Bacterial PH domain
CIGNPGHA_00991	7.06e-102	-	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside 2-deoxyribosyltransferase
CIGNPGHA_00992	1.57e-198	degV	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
CIGNPGHA_00993	0.0	nox	-	-	C	-	-	-	NADH oxidase
CIGNPGHA_00994	6.89e-75	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
CIGNPGHA_00995	2.72e-51	yrkD	-	-	S	-	-	-	Metal-sensitive transcriptional repressor
CIGNPGHA_00996	3.13e-86	crcB1	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CIGNPGHA_00997	2.22e-78	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CIGNPGHA_00998	8.33e-193	-	-	-	-	-	-	-	-
CIGNPGHA_00999	2.01e-210	-	-	-	I	-	-	-	Carboxylesterase family
CIGNPGHA_01000	1.44e-113	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
CIGNPGHA_01001	2.67e-209	-	-	-	-	-	-	-	-
CIGNPGHA_01002	0.0	pts14C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CIGNPGHA_01003	1.08e-216	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
CIGNPGHA_01004	4.53e-203	lysR5	-	-	K	-	-	-	LysR substrate binding domain
CIGNPGHA_01005	4.38e-183	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
CIGNPGHA_01006	2.42e-74	-	-	-	S	-	-	-	Protein of unknown function (DUF1634)
CIGNPGHA_01007	7.15e-179	-	-	-	IQ	-	-	-	Oxidoreductase, short chain dehydrogenase reductase family protein
CIGNPGHA_01008	3.51e-291	mdtG	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
CIGNPGHA_01009	4.89e-121	ywaC	2.7.6.5	-	S	ko:K00951,ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
CIGNPGHA_01010	2.36e-38	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
CIGNPGHA_01011	1.35e-226	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
CIGNPGHA_01013	0.0	-	-	-	S	-	-	-	membrane
CIGNPGHA_01014	4.29e-160	ciaR	-	-	K	ko:K14983	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	cheY-homologous receiver domain
CIGNPGHA_01015	5.25e-313	ciaH	2.7.13.3	-	T	ko:K14982	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
CIGNPGHA_01016	3.99e-231	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
CIGNPGHA_01017	0.0	malT	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
CIGNPGHA_01018	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
CIGNPGHA_01019	3.12e-100	-	-	-	-	-	-	-	-
CIGNPGHA_01020	5.85e-56	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CIGNPGHA_01021	1.31e-190	galM1	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
CIGNPGHA_01022	4.22e-207	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
CIGNPGHA_01023	1.91e-193	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
CIGNPGHA_01024	1.7e-84	-	-	-	K	-	-	-	MarR family
CIGNPGHA_01025	0.0	-	-	-	M	-	-	-	Parallel beta-helix repeats
CIGNPGHA_01026	4.82e-94	yugI	-	-	J	ko:K07570,ko:K07571	-	ko00000	general stress protein
CIGNPGHA_01027	4.07e-144	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CIGNPGHA_01028	7.54e-115	pgpA	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Phosphatidylglycerophosphatase A
CIGNPGHA_01029	1.98e-156	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
CIGNPGHA_01030	1.44e-184	dhrS4	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
CIGNPGHA_01031	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
CIGNPGHA_01032	4.39e-303	-	-	-	M	-	-	-	domain protein
CIGNPGHA_01033	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
CIGNPGHA_01034	7.81e-114	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
CIGNPGHA_01035	1.25e-153	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
CIGNPGHA_01036	7.44e-187	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
CIGNPGHA_01037	2.07e-126	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
CIGNPGHA_01038	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
CIGNPGHA_01039	2.17e-146	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
CIGNPGHA_01040	3.54e-194	yeaE	-	-	S	-	-	-	Aldo keto
CIGNPGHA_01041	0.0	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
CIGNPGHA_01042	2.16e-282	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CIGNPGHA_01043	4.88e-237	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
CIGNPGHA_01044	5.67e-96	-	-	-	-	ko:K02248	-	ko00000,ko00002,ko02044	-
CIGNPGHA_01046	6.48e-104	-	-	-	-	-	-	-	-
CIGNPGHA_01047	1.61e-64	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
CIGNPGHA_01048	3.54e-216	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
CIGNPGHA_01049	6.51e-221	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
CIGNPGHA_01050	1.68e-169	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
CIGNPGHA_01051	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
CIGNPGHA_01052	1.97e-173	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
CIGNPGHA_01053	1.95e-167	-	-	-	-	-	-	-	-
CIGNPGHA_01054	7.14e-231	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
CIGNPGHA_01055	2.45e-270	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
CIGNPGHA_01056	1.61e-72	-	-	-	-	-	-	-	-
CIGNPGHA_01057	3.9e-82	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
CIGNPGHA_01058	3.43e-179	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
CIGNPGHA_01059	3.31e-195	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
CIGNPGHA_01060	8.06e-33	-	-	-	-	-	-	-	-
CIGNPGHA_01061	5.31e-316	-	-	-	EGP	-	-	-	Major Facilitator
CIGNPGHA_01062	2.02e-106	-	-	-	S	-	-	-	ASCH
CIGNPGHA_01063	1.96e-168	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
CIGNPGHA_01064	5.13e-164	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CIGNPGHA_01065	3.17e-242	-	-	-	G	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
CIGNPGHA_01066	7.57e-97	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
CIGNPGHA_01067	0.0	-	-	-	EP	-	-	-	Psort location Cytoplasmic, score
CIGNPGHA_01068	4.85e-159	-	-	-	S	-	-	-	DJ-1/PfpI family
CIGNPGHA_01069	2.1e-71	-	-	-	K	-	-	-	Transcriptional
CIGNPGHA_01070	1.02e-232	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
CIGNPGHA_01071	1.74e-225	etfA	1.3.1.108	-	C	ko:K03522,ko:K22432	-	ko00000,ko01000,ko04147	Electron transfer flavoprotein FAD-binding domain
CIGNPGHA_01072	5.62e-182	fixA	-	-	C	ko:K03521	-	ko00000	Electron transfer flavoprotein domain
CIGNPGHA_01073	8.79e-263	-	1.3.8.1, 1.3.8.7	-	I	ko:K00248,ko:K00249,ko:K18244	ko00071,ko00280,ko00410,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map00650,map01100,map01110,map01120,map01130,map01200,map01212,map03320	ko00000,ko00001,ko00002,ko01000	Acyl-CoA dehydrogenase, C-terminal domain
CIGNPGHA_01074	1.8e-248	galM1	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
CIGNPGHA_01075	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
CIGNPGHA_01076	1.71e-49	-	-	-	-	-	-	-	-
CIGNPGHA_01077	0.0	lacP	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
CIGNPGHA_01078	2.5e-277	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CIGNPGHA_01079	5.36e-247	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
CIGNPGHA_01080	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
CIGNPGHA_01081	5.92e-236	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
CIGNPGHA_01083	0.0	rtpR	1.17.4.2	-	F	ko:K00527	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	ribonucleoside-triphosphate reductase activity
CIGNPGHA_01084	1.23e-117	-	-	-	S	-	-	-	Cob(I)alamin adenosyltransferase
CIGNPGHA_01087	1.07e-120	-	-	-	I	-	-	-	NUDIX domain
CIGNPGHA_01088	1.18e-94	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
CIGNPGHA_01089	4.02e-23	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
CIGNPGHA_01090	1.21e-94	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
CIGNPGHA_01091	8.13e-206	ropB	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
CIGNPGHA_01092	2.36e-273	-	-	-	EGP	-	-	-	Transmembrane secretion effector
CIGNPGHA_01093	0.0	gshR	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
CIGNPGHA_01094	2.98e-49	ygbF	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
CIGNPGHA_01096	6.83e-257	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
CIGNPGHA_01097	5.37e-48	-	-	-	-	-	-	-	-
CIGNPGHA_01098	3.02e-174	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
CIGNPGHA_01099	3.58e-291	gntT	-	-	EG	-	-	-	Citrate transporter
CIGNPGHA_01100	3.39e-227	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	pfkB family carbohydrate kinase
CIGNPGHA_01101	5.45e-138	-	4.1.2.43	-	G	ko:K08093	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Orotidine 5'-phosphate decarboxylase HUMPS family
CIGNPGHA_01102	2.02e-113	hxlB	5.3.1.27	-	M	ko:K08094	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	sugar phosphate isomerase involved in capsule formation
CIGNPGHA_01103	1.05e-225	kdgR	-	-	K	ko:K02525	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
CIGNPGHA_01104	2.33e-108	-	-	-	-	-	-	-	-
CIGNPGHA_01105	0.0	-	-	-	L	-	-	-	DNA helicase
CIGNPGHA_01106	1.16e-243	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
CIGNPGHA_01107	2.2e-131	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
CIGNPGHA_01108	1.38e-55	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
CIGNPGHA_01109	7.25e-284	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
CIGNPGHA_01110	1.23e-225	-	-	-	-	-	-	-	-
CIGNPGHA_01111	1.69e-167	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
CIGNPGHA_01112	8.41e-67	-	-	-	-	-	-	-	-
CIGNPGHA_01113	6.98e-205	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
CIGNPGHA_01114	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CIGNPGHA_01115	2.71e-186	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
CIGNPGHA_01116	9.98e-128	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CIGNPGHA_01117	4.9e-208	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
CIGNPGHA_01118	1.14e-48	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
CIGNPGHA_01119	3.2e-207	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CIGNPGHA_01120	1.51e-250	-	-	-	M	-	-	-	domain protein
CIGNPGHA_01121	5.05e-184	-	-	-	K	-	-	-	Helix-turn-helix domain
CIGNPGHA_01122	9.98e-215	-	-	-	-	-	-	-	-
CIGNPGHA_01123	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
CIGNPGHA_01124	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
CIGNPGHA_01125	7.71e-277	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
CIGNPGHA_01126	2.61e-235	pgdA	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	polysaccharide deacetylase
CIGNPGHA_01127	3.66e-77	-	-	-	-	-	-	-	-
CIGNPGHA_01128	1.58e-133	-	-	-	GM	-	-	-	NAD(P)H-binding
CIGNPGHA_01129	1.1e-231	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
CIGNPGHA_01130	1.42e-289	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
CIGNPGHA_01131	4.15e-120	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
CIGNPGHA_01132	7.6e-199	drrA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
CIGNPGHA_01133	5.93e-165	drrB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
CIGNPGHA_01134	4.28e-128	-	-	-	K	-	-	-	LysR substrate binding domain
CIGNPGHA_01135	9.97e-87	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
CIGNPGHA_01136	2.97e-213	-	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
CIGNPGHA_01137	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
CIGNPGHA_01138	1.39e-112	ccl	-	-	S	-	-	-	QueT transporter
CIGNPGHA_01142	0.0	-	3.4.19.1	-	E	ko:K01303	-	ko00000,ko01000,ko01002	Prolyl oligopeptidase family
CIGNPGHA_01143	1.42e-218	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CIGNPGHA_01144	7.46e-59	-	-	-	-	-	-	-	-
CIGNPGHA_01145	3.64e-86	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
CIGNPGHA_01146	0.0	nhaP2	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
CIGNPGHA_01147	0.0	yfkN	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
CIGNPGHA_01148	0.0	astA	2.8.2.22	-	M	ko:K01023	-	ko00000,ko01000	Arylsulfotransferase Ig-like domain
CIGNPGHA_01149	1.55e-151	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
CIGNPGHA_01150	1.44e-199	rihA	-	-	F	ko:K01250	-	ko00000,ko01000	Inosine-uridine preferring nucleoside hydrolase
CIGNPGHA_01152	1.71e-239	nupC	-	-	F	ko:K11535	-	ko00000,ko02000	Na+ dependent nucleoside transporter C-terminus
CIGNPGHA_01153	1.78e-188	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
CIGNPGHA_01154	3.19e-94	-	-	-	S	-	-	-	Membrane
CIGNPGHA_01155	1.25e-143	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
CIGNPGHA_01156	5.77e-156	psuK	2.7.1.83	-	G	ko:K16328	ko00240,map00240	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
CIGNPGHA_01157	1.08e-139	psuK	2.7.1.83	-	GK	ko:K16328	ko00240,map00240	ko00000,ko00001,ko01000	Winged helix-turn-helix DNA-binding
CIGNPGHA_01159	6.09e-228	-	-	-	K	ko:K02529,ko:K03435	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
CIGNPGHA_01160	1.48e-69	-	-	-	S	-	-	-	Pentapeptide repeats (8 copies)
CIGNPGHA_01161	4.43e-129	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
CIGNPGHA_01162	5.54e-111	hmpT	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
CIGNPGHA_01163	3.8e-180	thiD	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
CIGNPGHA_01164	0.0	norG_2	-	-	K	-	-	-	Aminotransferase class I and II
CIGNPGHA_01165	9.85e-283	ywtF_2	-	-	K	-	-	-	Cell envelope-related transcriptional attenuator domain
CIGNPGHA_01166	1.01e-177	-	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
CIGNPGHA_01167	4.71e-189	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CIGNPGHA_01168	6.03e-204	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CIGNPGHA_01169	3.11e-290	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Cell cycle protein
CIGNPGHA_01170	9.6e-27	-	-	-	-	-	-	-	-
CIGNPGHA_01171	1.31e-76	-	-	-	-	-	-	-	-
CIGNPGHA_01173	1.23e-92	-	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase
CIGNPGHA_01174	6.12e-184	-	-	-	S	-	-	-	Membrane
CIGNPGHA_01175	8.46e-239	tdh	1.1.1.14	-	C	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
CIGNPGHA_01176	1.81e-221	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
CIGNPGHA_01177	5.9e-98	-	-	-	-	-	-	-	-
CIGNPGHA_01178	9.54e-262	gldA	1.1.1.6	-	C	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	dehydrogenase
CIGNPGHA_01179	8.43e-65	ykkC	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
CIGNPGHA_01180	3.77e-68	ykkD	-	-	P	ko:K18925	-	ko00000,ko00002,ko02000	Multidrug resistance protein
CIGNPGHA_01181	1.2e-128	yokL3	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
CIGNPGHA_01182	8.63e-188	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
CIGNPGHA_01184	0.0	treP	2.4.1.64	GH65	G	ko:K05342	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
CIGNPGHA_01185	4.28e-252	-	-	-	I	-	-	-	alpha/beta hydrolase fold
CIGNPGHA_01186	0.0	xylP2	-	-	G	-	-	-	symporter
CIGNPGHA_01187	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
CIGNPGHA_01188	4.9e-105	-	-	-	-	-	-	-	-
CIGNPGHA_01190	7.38e-228	cytR	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	Transcriptional regulator, LacI family
CIGNPGHA_01191	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
CIGNPGHA_01192	0.0	-	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
CIGNPGHA_01193	2.22e-146	-	-	-	-	-	-	-	-
CIGNPGHA_01194	1.19e-97	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
CIGNPGHA_01195	4.33e-69	-	-	-	K	-	-	-	Transcriptional regulator
CIGNPGHA_01196	1.3e-35	-	-	-	C	-	-	-	alcohol dehydrogenase
CIGNPGHA_01197	6.23e-94	-	-	-	C	-	-	-	alcohol dehydrogenase
CIGNPGHA_01198	4.1e-93	-	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Bacterial transferase hexapeptide (six repeats)
CIGNPGHA_01199	4.86e-279	-	-	-	C	-	-	-	Oxidoreductase
CIGNPGHA_01201	1.83e-84	-	-	-	K	-	-	-	Transcriptional regulator, HxlR family
CIGNPGHA_01202	1.04e-219	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CIGNPGHA_01203	1.57e-281	dhaT	1.1.1.202	-	C	ko:K00086	ko00561,ko00640,map00561,map00640	ko00000,ko00001,ko01000	Dehydrogenase
CIGNPGHA_01204	7.8e-155	-	3.8.1.2	-	S	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
CIGNPGHA_01205	2.14e-141	-	-	-	S	ko:K15770	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	GyrI-like small molecule binding domain
CIGNPGHA_01206	3.12e-286	-	-	-	U	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
CIGNPGHA_01207	1.89e-157	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
CIGNPGHA_01208	5.38e-231	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
CIGNPGHA_01209	2.81e-112	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
CIGNPGHA_01210	1.66e-270	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
CIGNPGHA_01211	1.24e-83	-	-	-	G	-	-	-	Domain of unknown function (DUF386)
CIGNPGHA_01212	7.08e-275	-	-	-	G	-	-	-	Sugar (and other) transporter
CIGNPGHA_01213	5.25e-106	-	-	-	G	-	-	-	Domain of unknown function (DUF386)
CIGNPGHA_01214	1.88e-165	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
CIGNPGHA_01215	9.44e-185	sga	5.1.3.22	-	G	ko:K03079	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Xylose isomerase-like TIM barrel
CIGNPGHA_01216	4.39e-295	-	2.7.1.53	-	G	ko:K00880	ko00040,ko00053,map00040,map00053	ko00000,ko00001,ko01000	Xylulose kinase
CIGNPGHA_01217	1.79e-209	-	-	-	-	-	-	-	-
CIGNPGHA_01218	4.54e-199	gyaR	1.1.1.26, 1.1.1.399, 1.1.1.95	-	CH	ko:K00015,ko:K00058	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CIGNPGHA_01219	5.15e-179	-	-	-	K	ko:K02525	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
CIGNPGHA_01220	4.99e-101	-	-	-	S	-	-	-	NAD:arginine ADP-ribosyltransferase
CIGNPGHA_01221	9.29e-251	ysdE	-	-	P	-	-	-	Citrate transporter
CIGNPGHA_01222	1.06e-155	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
CIGNPGHA_01223	2.44e-193	-	-	-	T	-	-	-	diguanylate cyclase
CIGNPGHA_01224	5.55e-29	-	-	-	-	-	-	-	-
CIGNPGHA_01225	5.22e-75	-	-	-	-	-	-	-	-
CIGNPGHA_01226	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
CIGNPGHA_01227	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
CIGNPGHA_01228	2.37e-248	ampC	-	-	V	-	-	-	Beta-lactamase
CIGNPGHA_01229	8.73e-171	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
CIGNPGHA_01230	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Mur ligase, middle domain
CIGNPGHA_01231	7.63e-143	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
CIGNPGHA_01232	2.65e-247	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CIGNPGHA_01233	5.43e-194	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
CIGNPGHA_01234	5.53e-242	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
CIGNPGHA_01235	4.47e-295	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CIGNPGHA_01236	1.06e-145	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CIGNPGHA_01237	1.55e-162	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
CIGNPGHA_01238	7.38e-37	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CIGNPGHA_01239	3.81e-77	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CIGNPGHA_01240	4.44e-117	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CIGNPGHA_01241	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CIGNPGHA_01242	1.52e-208	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CIGNPGHA_01243	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CIGNPGHA_01244	4.49e-88	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
CIGNPGHA_01245	1.11e-45	ywzB	-	-	S	-	-	-	Protein of unknown function (DUF1146)
CIGNPGHA_01246	5e-310	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CIGNPGHA_01247	4.82e-230	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
CIGNPGHA_01248	1.11e-69	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
CIGNPGHA_01249	5.6e-45	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
CIGNPGHA_01250	9.13e-282	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
CIGNPGHA_01251	2.71e-66	gcsH2	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	glycine cleavage
CIGNPGHA_01252	8.69e-149	-	-	-	O	-	-	-	Zinc-dependent metalloprotease
CIGNPGHA_01253	4.58e-69	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
CIGNPGHA_01254	7.47e-190	-	3.1.3.23	-	S	ko:K07757	-	ko00000,ko01000	Sucrose-6F-phosphate phosphohydrolase
CIGNPGHA_01255	4.39e-39	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
CIGNPGHA_01256	4.1e-124	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
CIGNPGHA_01257	1.05e-275	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
CIGNPGHA_01258	2.93e-180	yqeM	-	-	Q	-	-	-	Methyltransferase
CIGNPGHA_01259	1.28e-77	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
CIGNPGHA_01260	6.24e-139	yqeK	-	-	H	-	-	-	Hydrolase, HD family
CIGNPGHA_01261	1.58e-152	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CIGNPGHA_01262	1.5e-64	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
CIGNPGHA_01263	9.12e-285	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
CIGNPGHA_01264	2.6e-134	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
CIGNPGHA_01265	6.09e-72	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CIGNPGHA_01266	5.7e-36	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
CIGNPGHA_01267	2.31e-101	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CIGNPGHA_01268	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CIGNPGHA_01269	3.88e-211	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
CIGNPGHA_01270	1.34e-311	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
CIGNPGHA_01271	4.94e-114	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CIGNPGHA_01272	4.86e-142	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CIGNPGHA_01273	1.59e-208	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
CIGNPGHA_01274	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CIGNPGHA_01275	0.0	guaD	3.5.4.3	-	F	ko:K01487	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Amidohydrolase family
CIGNPGHA_01276	1.7e-299	-	-	-	F	ko:K03458	-	ko00000	Permease
CIGNPGHA_01277	4.23e-153	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
CIGNPGHA_01278	2.69e-169	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
CIGNPGHA_01279	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
CIGNPGHA_01280	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
CIGNPGHA_01283	1.91e-150	-	-	-	-	-	-	-	-
CIGNPGHA_01285	2.61e-83	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
CIGNPGHA_01286	6.01e-54	-	-	-	-	-	-	-	-
CIGNPGHA_01287	1.3e-124	-	-	-	-	-	-	-	-
CIGNPGHA_01288	4.83e-59	-	-	-	-	-	-	-	-
CIGNPGHA_01289	2.4e-144	-	-	-	GM	-	-	-	NmrA-like family
CIGNPGHA_01290	1.03e-198	-	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Metalloenzyme superfamily
CIGNPGHA_01291	4.23e-287	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Nucleoside
CIGNPGHA_01292	7.77e-283	pbuO_1	-	-	S	ko:K06901	-	ko00000,ko02000	Permease family
CIGNPGHA_01293	7.6e-216	rihA	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
CIGNPGHA_01294	7.03e-213	-	3.1.4.17, 3.1.4.53	-	S	ko:K01120,ko:K03651	ko00230,ko02025,map00230,map02025	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
CIGNPGHA_01295	2.3e-170	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
CIGNPGHA_01296	5.86e-191	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
CIGNPGHA_01297	3.52e-176	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
CIGNPGHA_01298	1.44e-199	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
CIGNPGHA_01299	1.15e-43	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
CIGNPGHA_01300	2.3e-255	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
CIGNPGHA_01301	2.48e-170	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
CIGNPGHA_01302	3.1e-138	-	-	-	-	-	-	-	-
CIGNPGHA_01303	1.42e-267	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
CIGNPGHA_01304	4.64e-159	vanR	-	-	K	-	-	-	response regulator
CIGNPGHA_01305	1.68e-275	hpk31	-	-	T	-	-	-	Histidine kinase
CIGNPGHA_01306	6.01e-304	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
CIGNPGHA_01307	2.64e-215	tas	-	-	C	-	-	-	Aldo/keto reductase family
CIGNPGHA_01308	1.85e-82	-	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	glycine cleavage
CIGNPGHA_01309	7.02e-245	-	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
CIGNPGHA_01310	2.47e-68	-	-	-	-	-	-	-	-
CIGNPGHA_01311	0.0	-	-	-	M	-	-	-	domain, Protein
CIGNPGHA_01312	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
CIGNPGHA_01313	3.84e-281	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific adenine glycosylase
CIGNPGHA_01314	2.63e-69	-	-	-	-	-	-	-	-
CIGNPGHA_01315	1.41e-142	mhqD	-	-	S	ko:K06999	-	ko00000	Dienelactone hydrolase family
CIGNPGHA_01316	2.32e-43	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
CIGNPGHA_01317	1.04e-49	-	-	-	S	-	-	-	Cytochrome B5
CIGNPGHA_01319	1.76e-44	-	-	-	-	-	-	-	-
CIGNPGHA_01321	4.12e-158	yrkL	-	-	S	-	-	-	Flavodoxin-like fold
CIGNPGHA_01322	8.02e-25	-	-	-	-	-	-	-	-
CIGNPGHA_01323	8.74e-194	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
CIGNPGHA_01324	9.2e-64	-	-	-	-	-	-	-	-
CIGNPGHA_01325	7.25e-305	codA	3.5.4.1	-	F	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000	cytosine deaminase
CIGNPGHA_01326	1.89e-110	-	-	-	-	-	-	-	-
CIGNPGHA_01327	4.49e-188	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CIGNPGHA_01328	5.2e-108	-	-	-	S	ko:K04750	-	ko00000	3-demethylubiquinone-9 3-methyltransferase
CIGNPGHA_01329	1.53e-146	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
CIGNPGHA_01330	0.0	-	-	-	U	ko:K03451	-	ko00000	Belongs to the BCCT transporter (TC 2.A.15) family
CIGNPGHA_01331	2.33e-103	-	-	-	T	-	-	-	Universal stress protein family
CIGNPGHA_01332	3.02e-160	-	-	-	S	-	-	-	HAD-hyrolase-like
CIGNPGHA_01333	1.01e-91	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
CIGNPGHA_01334	1.35e-153	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
CIGNPGHA_01335	1.99e-201	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
CIGNPGHA_01336	1e-132	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
CIGNPGHA_01337	1.94e-216	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
CIGNPGHA_01338	1.06e-235	-	-	-	K	-	-	-	Transcriptional regulator
CIGNPGHA_01339	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
CIGNPGHA_01340	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
CIGNPGHA_01341	1.83e-136	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
CIGNPGHA_01342	4.95e-214	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
CIGNPGHA_01343	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CIGNPGHA_01344	1.68e-121	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CIGNPGHA_01345	5.87e-228	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
CIGNPGHA_01346	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CIGNPGHA_01347	2.53e-210	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
CIGNPGHA_01348	5.64e-172	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CIGNPGHA_01349	6.95e-203	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CIGNPGHA_01351	9.5e-98	abiGI	-	-	K	-	-	-	Psort location Cytoplasmic, score
CIGNPGHA_01354	6.13e-165	-	-	-	-	-	-	-	-
CIGNPGHA_01355	6.56e-48	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
CIGNPGHA_01356	9.91e-137	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
CIGNPGHA_01357	1.47e-214	XK27_03630	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
CIGNPGHA_01358	1.23e-190	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
CIGNPGHA_01359	1.06e-147	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
CIGNPGHA_01360	5.79e-147	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
CIGNPGHA_01361	6e-245	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CIGNPGHA_01362	4.65e-187	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
CIGNPGHA_01363	7.4e-126	tag2	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
CIGNPGHA_01364	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
CIGNPGHA_01365	0.0	-	3.2.1.21, 3.2.1.52	GH3	G	ko:K01207,ko:K05349	ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501	ko00000,ko00001,ko00002,ko01000	hydrolase, family 3
CIGNPGHA_01366	1.46e-236	pva2	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
CIGNPGHA_01367	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
CIGNPGHA_01368	1.58e-263	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
CIGNPGHA_01369	2.12e-136	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
CIGNPGHA_01370	1.11e-192	-	-	-	S	-	-	-	Zinc-dependent metalloprotease
CIGNPGHA_01371	2.25e-214	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	hydrolase, family 25
CIGNPGHA_01372	2.41e-257	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
CIGNPGHA_01373	3.88e-71	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	decarboxylase
CIGNPGHA_01374	1.06e-100	yphH	-	-	S	-	-	-	Cupin domain
CIGNPGHA_01375	2.3e-96	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
CIGNPGHA_01376	5.57e-129	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
CIGNPGHA_01378	1.2e-234	-	-	-	-	-	-	-	-
CIGNPGHA_01379	2.18e-19	-	-	-	-	-	-	-	-
CIGNPGHA_01380	0.0	arcD	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
CIGNPGHA_01381	0.0	arcT	-	-	E	-	-	-	Dipeptidase
CIGNPGHA_01383	6.72e-266	-	-	-	-	-	-	-	-
CIGNPGHA_01384	1.58e-138	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
CIGNPGHA_01385	1.4e-213	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
CIGNPGHA_01386	2.31e-283	-	-	-	U	-	-	-	Belongs to the major facilitator superfamily
CIGNPGHA_01387	1.26e-51	-	-	-	S	-	-	-	Protein of unknown function (DUF3781)
CIGNPGHA_01388	4.28e-53	-	-	-	-	-	-	-	-
CIGNPGHA_01389	1.65e-108	yafP	-	-	K	ko:K03830	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
CIGNPGHA_01390	3.05e-169	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CIGNPGHA_01391	0.0	-	-	-	M	-	-	-	domain protein
CIGNPGHA_01392	6.11e-238	ydbI	-	-	K	-	-	-	AI-2E family transporter
CIGNPGHA_01393	1.25e-269	xylR	-	-	GK	-	-	-	ROK family
CIGNPGHA_01394	4.7e-177	-	-	-	-	-	-	-	-
CIGNPGHA_01395	1.14e-302	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
CIGNPGHA_01396	1.3e-71	-	-	-	S	-	-	-	branched-chain amino acid
CIGNPGHA_01397	2.86e-176	azlC	-	-	E	-	-	-	AzlC protein
CIGNPGHA_01398	5.57e-115	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
CIGNPGHA_01399	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
CIGNPGHA_01400	4.13e-43	-	-	-	S	ko:K21449	-	ko00000,ko02000	Domain of unknown function (DUF4430)
CIGNPGHA_01401	4.64e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
CIGNPGHA_01402	1.43e-75	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
CIGNPGHA_01403	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
CIGNPGHA_01404	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CIGNPGHA_01405	2.73e-241	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
CIGNPGHA_01406	3.98e-49	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CIGNPGHA_01407	5.47e-167	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
CIGNPGHA_01408	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
CIGNPGHA_01409	9.47e-249	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
CIGNPGHA_01410	8.53e-76	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CIGNPGHA_01411	3.49e-280	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CIGNPGHA_01412	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
CIGNPGHA_01413	1.09e-272	-	-	-	S	-	-	-	associated with various cellular activities
CIGNPGHA_01414	0.0	-	-	-	S	-	-	-	Putative metallopeptidase domain
CIGNPGHA_01415	7.31e-65	-	-	-	-	-	-	-	-
CIGNPGHA_01416	3.48e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
CIGNPGHA_01417	2.63e-53	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
CIGNPGHA_01418	3.58e-119	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CIGNPGHA_01419	9.06e-183	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
CIGNPGHA_01420	2.13e-76	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
CIGNPGHA_01421	5.18e-128	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CIGNPGHA_01422	8.9e-96	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
CIGNPGHA_01423	2.79e-97	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CIGNPGHA_01424	3.85e-201	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CIGNPGHA_01425	6.09e-310	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
CIGNPGHA_01426	6.72e-47	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
CIGNPGHA_01427	9.5e-208	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
CIGNPGHA_01428	1.62e-189	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
CIGNPGHA_01429	9.88e-100	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
CIGNPGHA_01430	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
CIGNPGHA_01432	2.72e-67	-	-	-	-	-	-	-	-
CIGNPGHA_01433	2.35e-134	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
CIGNPGHA_01434	2.53e-42	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
CIGNPGHA_01435	1.09e-274	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CIGNPGHA_01436	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CIGNPGHA_01437	3.11e-220	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CIGNPGHA_01438	1.7e-314	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CIGNPGHA_01439	6.05e-169	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
CIGNPGHA_01440	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
CIGNPGHA_01441	1.94e-215	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
CIGNPGHA_01442	5.46e-152	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
CIGNPGHA_01443	1.77e-165	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
CIGNPGHA_01444	3.14e-66	-	-	-	-	-	-	-	-
CIGNPGHA_01445	2.31e-257	tagH	3.6.3.40	-	GM	ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
CIGNPGHA_01446	6.01e-45	copZ	-	-	P	-	-	-	Heavy-metal-associated domain
CIGNPGHA_01447	1.05e-121	dpsB	-	-	P	-	-	-	Belongs to the Dps family
CIGNPGHA_01448	7.11e-185	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
CIGNPGHA_01449	1.69e-231	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
CIGNPGHA_01450	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
CIGNPGHA_01451	0.0	-	-	CBM50	NU	ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
CIGNPGHA_01452	4.46e-167	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
CIGNPGHA_01453	3.46e-18	-	-	-	-	-	-	-	-
CIGNPGHA_01454	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
CIGNPGHA_01455	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CIGNPGHA_01456	2e-188	ybbR	-	-	S	-	-	-	YbbR-like protein
CIGNPGHA_01457	1.62e-195	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CIGNPGHA_01458	9.08e-157	-	-	-	S	-	-	-	Protein of unknown function (DUF1361)
CIGNPGHA_01459	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
CIGNPGHA_01460	2.34e-210	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
CIGNPGHA_01461	3.87e-193	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
CIGNPGHA_01462	6.15e-132	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
CIGNPGHA_01463	9.98e-35	-	-	-	-	-	-	-	-
CIGNPGHA_01464	0.0	tagE2	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
CIGNPGHA_01465	0.0	tagE3	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
CIGNPGHA_01466	2.14e-19	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
CIGNPGHA_01467	4.34e-138	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
CIGNPGHA_01468	1.84e-262	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
CIGNPGHA_01469	2.71e-199	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
CIGNPGHA_01470	1.72e-125	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
CIGNPGHA_01471	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
CIGNPGHA_01472	4.92e-18	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
CIGNPGHA_01473	1.24e-79	-	-	-	S	-	-	-	Protein of unknown function (DUF3397)
CIGNPGHA_01474	2.68e-13	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
CIGNPGHA_01475	2.62e-294	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
CIGNPGHA_01476	1.38e-102	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
CIGNPGHA_01477	3.53e-226	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
CIGNPGHA_01478	1.22e-79	ftsL	-	-	D	-	-	-	Cell division protein FtsL
CIGNPGHA_01479	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
CIGNPGHA_01480	3.06e-236	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CIGNPGHA_01481	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CIGNPGHA_01482	1.69e-256	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CIGNPGHA_01483	8.63e-194	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
CIGNPGHA_01484	7.1e-309	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
CIGNPGHA_01485	1.48e-287	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CIGNPGHA_01486	1.49e-97	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
CIGNPGHA_01487	1.98e-54	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
CIGNPGHA_01488	2.81e-184	ylmH	-	-	S	-	-	-	S4 domain protein
CIGNPGHA_01489	3.17e-133	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
CIGNPGHA_01490	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CIGNPGHA_01491	4.08e-47	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
CIGNPGHA_01492	2.04e-122	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
CIGNPGHA_01493	1.93e-47	-	-	-	-	-	-	-	-
CIGNPGHA_01494	3.68e-161	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CIGNPGHA_01495	8.2e-288	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
CIGNPGHA_01496	1.79e-77	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
CIGNPGHA_01497	4.16e-283	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
CIGNPGHA_01498	2.23e-156	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
CIGNPGHA_01499	5.63e-154	-	-	-	S	-	-	-	repeat protein
CIGNPGHA_01500	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
CIGNPGHA_01501	4.45e-227	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CIGNPGHA_01502	3.68e-161	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
CIGNPGHA_01503	6.33e-157	yckA	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
CIGNPGHA_01504	8.12e-205	yckB	-	-	ET	ko:K02030,ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
CIGNPGHA_01505	0.0	nylA	3.5.1.4	-	J	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	Belongs to the amidase family
CIGNPGHA_01506	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
CIGNPGHA_01507	6.58e-200	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CIGNPGHA_01508	2.25e-241	yghZ	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
CIGNPGHA_01509	8.04e-237	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
CIGNPGHA_01510	1.45e-205	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CIGNPGHA_01511	0.0	tkt2	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CIGNPGHA_01512	1e-216	ykfC	3.4.14.13	-	M	ko:K20742	-	ko00000,ko01000,ko01002	NlpC/P60 family
CIGNPGHA_01513	6.42e-217	ypuA	-	-	S	-	-	-	Protein of unknown function (DUF1002)
CIGNPGHA_01514	1.36e-201	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
CIGNPGHA_01515	6.66e-39	-	-	-	-	-	-	-	-
CIGNPGHA_01516	1.11e-236	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic
CIGNPGHA_01517	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CIGNPGHA_01518	9.82e-45	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
CIGNPGHA_01519	9.18e-105	-	-	-	-	-	-	-	-
CIGNPGHA_01520	9.7e-133	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
CIGNPGHA_01521	4.77e-271	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
CIGNPGHA_01522	1.15e-232	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
CIGNPGHA_01523	9.08e-283	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
CIGNPGHA_01524	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
CIGNPGHA_01525	1.16e-209	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	L-malate dehydrogenase activity
CIGNPGHA_01526	2.07e-60	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
CIGNPGHA_01527	7.71e-184	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
CIGNPGHA_01528	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
CIGNPGHA_01529	1.04e-267	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
CIGNPGHA_01530	1.33e-57	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
CIGNPGHA_01531	2.66e-126	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
CIGNPGHA_01532	4.98e-107	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CIGNPGHA_01533	1.54e-249	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
CIGNPGHA_01534	3.18e-140	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CIGNPGHA_01535	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
CIGNPGHA_01536	1.01e-116	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
CIGNPGHA_01537	3.35e-156	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
CIGNPGHA_01538	3.12e-145	-	-	-	T	-	-	-	Tyrosine phosphatase family
CIGNPGHA_01539	4.33e-159	-	-	-	-	-	-	-	-
CIGNPGHA_01540	2.77e-159	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
CIGNPGHA_01541	1.52e-81	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
CIGNPGHA_01542	1.27e-222	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
CIGNPGHA_01543	9.4e-110	gpo	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
CIGNPGHA_01544	7.25e-162	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
CIGNPGHA_01545	1.03e-266	-	-	-	EGP	ko:K02030,ko:K07552	-	ko00000,ko00002,ko02000	Drug resistance transporter Bcr CflA subfamily
CIGNPGHA_01546	5.02e-187	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
CIGNPGHA_01547	4.2e-201	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
CIGNPGHA_01548	1.71e-146	-	-	-	-	-	-	-	-
CIGNPGHA_01550	1.14e-170	-	-	-	S	-	-	-	KR domain
CIGNPGHA_01551	7.35e-87	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
CIGNPGHA_01552	5.5e-83	asp2	-	-	S	-	-	-	Asp23 family, cell envelope-related function
CIGNPGHA_01553	4.16e-93	-	-	-	S	-	-	-	Asp23 family, cell envelope-related function
CIGNPGHA_01554	1.02e-34	-	-	-	-	-	-	-	-
CIGNPGHA_01555	1.23e-119	-	-	-	-	-	-	-	-
CIGNPGHA_01556	4.98e-44	-	-	-	S	-	-	-	Transglycosylase associated protein
CIGNPGHA_01557	2.8e-202	-	-	-	-	-	-	-	-
CIGNPGHA_01558	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
CIGNPGHA_01559	1.2e-113	-	-	-	U	-	-	-	Major Facilitator Superfamily
CIGNPGHA_01560	2.17e-127	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
CIGNPGHA_01561	1.88e-197	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
CIGNPGHA_01562	7.79e-192	-	-	-	-	-	-	-	-
CIGNPGHA_01563	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
CIGNPGHA_01564	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
CIGNPGHA_01565	1.67e-271	-	-	-	S	-	-	-	nuclear-transcribed mRNA catabolic process, no-go decay
CIGNPGHA_01566	9.61e-84	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
CIGNPGHA_01567	1.74e-274	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CIGNPGHA_01569	1.45e-80	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
CIGNPGHA_01570	7.47e-148	-	-	-	S	-	-	-	(CBS) domain
CIGNPGHA_01572	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
CIGNPGHA_01573	5.62e-225	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
CIGNPGHA_01574	1.05e-131	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
CIGNPGHA_01575	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CIGNPGHA_01576	0.0	yabM	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
CIGNPGHA_01577	7.09e-53	yabO	-	-	J	-	-	-	S4 domain protein
CIGNPGHA_01578	9.05e-58	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
CIGNPGHA_01579	9.26e-118	-	-	-	S	-	-	-	Iron Transport-associated domain
CIGNPGHA_01580	4.98e-256	-	-	-	M	-	-	-	Iron Transport-associated domain
CIGNPGHA_01581	9.62e-154	-	-	-	M	ko:K14193	ko05150,map05150	ko00000,ko00001	Iron Transport-associated domain
CIGNPGHA_01582	1.12e-209	isdE	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
CIGNPGHA_01583	8.57e-222	isdF	-	-	U	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CIGNPGHA_01584	3.16e-182	fepC	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
CIGNPGHA_01585	1.94e-217	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
CIGNPGHA_01586	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CIGNPGHA_01587	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
CIGNPGHA_01588	4.33e-195	-	-	-	M	ko:K07271	-	ko00000,ko01000	LicD family
CIGNPGHA_01589	3.69e-114	-	-	-	S	-	-	-	Domain of unknown function (DUF5067)
CIGNPGHA_01590	8.55e-99	-	-	-	K	-	-	-	Transcriptional regulator
CIGNPGHA_01591	2.39e-34	-	-	-	-	-	-	-	-
CIGNPGHA_01592	1.08e-102	-	-	-	O	-	-	-	OsmC-like protein
CIGNPGHA_01593	2.26e-33	-	-	-	-	-	-	-	-
CIGNPGHA_01595	1.72e-73	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
CIGNPGHA_01596	4.24e-114	-	-	-	-	-	-	-	-
CIGNPGHA_01597	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
CIGNPGHA_01598	0.0	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Peptidase dimerisation domain
CIGNPGHA_01599	1.32e-119	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
CIGNPGHA_01601	3.39e-34	azoR	-	-	C	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CIGNPGHA_01602	5.04e-312	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	Major Facilitator Superfamily
CIGNPGHA_01603	3.25e-273	yttB	-	-	EGP	-	-	-	Major Facilitator
CIGNPGHA_01604	3.88e-149	-	-	-	-	-	-	-	-
CIGNPGHA_01605	1.85e-204	-	1.1.1.65	-	C	ko:K05275	ko00750,ko01100,ko01120,map00750,map01100,map01120	ko00000,ko00001,ko01000	Aldo keto reductase
CIGNPGHA_01606	1.65e-204	-	2.3.1.81	-	V	ko:K00662	-	ko00000,ko01000,ko01504	Aminoglycoside 3-N-acetyltransferase
CIGNPGHA_01607	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CIGNPGHA_01608	3.49e-102	-	-	-	S	ko:K02348	-	ko00000	Gnat family
CIGNPGHA_01609	4.64e-96	-	-	-	K	-	-	-	Transcriptional regulator
CIGNPGHA_01610	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CIGNPGHA_01613	5.81e-63	-	-	-	K	-	-	-	Helix-turn-helix domain
CIGNPGHA_01615	3.28e-61	-	-	-	-	-	-	-	-
CIGNPGHA_01616	5.26e-148	-	-	-	GM	-	-	-	NAD(P)H-binding
CIGNPGHA_01617	1.84e-80	-	-	-	-	-	-	-	-
CIGNPGHA_01618	5.01e-138	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Peroxiredoxin
CIGNPGHA_01619	3.25e-291	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
CIGNPGHA_01620	8.65e-144	aqpZ	-	-	U	ko:K06188	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
CIGNPGHA_01621	2.25e-76	-	-	-	S	-	-	-	Domain of unknown function (DU1801)
CIGNPGHA_01622	0.0	epsA	-	-	I	-	-	-	PAP2 superfamily
CIGNPGHA_01623	9.53e-93	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
CIGNPGHA_01624	9.15e-207	-	-	-	K	-	-	-	LysR substrate binding domain
CIGNPGHA_01625	0.0	yclC	4.1.1.61, 4.1.1.98	-	H	ko:K01612,ko:K03182,ko:K16874	ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
CIGNPGHA_01626	1.87e-126	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
CIGNPGHA_01627	2.34e-93	-	-	-	-	-	-	-	-
CIGNPGHA_01628	3.16e-204	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type cobalt transport system permease component CbiQ and related transporters
CIGNPGHA_01629	0.0	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
CIGNPGHA_01630	8.08e-147	-	-	-	S	ko:K16927	-	ko00000,ko00002,ko02000	ECF-type riboflavin transporter, S component
CIGNPGHA_01631	1.43e-229	-	-	-	U	-	-	-	FFAT motif binding
CIGNPGHA_01632	1.35e-122	-	-	-	S	-	-	-	Domain of unknown function (DUF4430)
CIGNPGHA_01633	1.33e-34	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
CIGNPGHA_01634	3.04e-53	pduN	-	-	CQ	ko:K04028	-	ko00000	Ethanolamine utilisation protein EutN/carboxysome
CIGNPGHA_01635	6.81e-172	namA	-	-	C	-	-	-	Oxidoreductase
CIGNPGHA_01636	1.57e-262	-	-	-	EGP	-	-	-	Major Facilitator
CIGNPGHA_01637	9.21e-99	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
CIGNPGHA_01638	2.5e-104	-	-	-	K	-	-	-	Transcriptional regulator
CIGNPGHA_01639	3.29e-233	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CIGNPGHA_01640	1.84e-49	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CIGNPGHA_01641	4.92e-212	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
CIGNPGHA_01642	2.74e-157	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
CIGNPGHA_01643	5.36e-289	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
CIGNPGHA_01644	3.4e-93	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
CIGNPGHA_01645	5.31e-90	fabZ2	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
CIGNPGHA_01646	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
CIGNPGHA_01647	7.49e-198	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CIGNPGHA_01648	6.61e-181	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
CIGNPGHA_01649	4.26e-171	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
CIGNPGHA_01650	6.51e-176	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
CIGNPGHA_01651	6.62e-111	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
CIGNPGHA_01652	8.49e-66	-	-	-	S	-	-	-	MazG nucleotide pyrophosphohydrolase domain
CIGNPGHA_01653	6.43e-117	entB	-	-	Q	-	-	-	Isochorismatase family
CIGNPGHA_01654	1.35e-102	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
CIGNPGHA_01655	5.15e-91	-	-	-	K	-	-	-	LytTr DNA-binding domain
CIGNPGHA_01656	2.1e-65	-	-	-	N	ko:K18843	-	ko00000,ko02048	PFAM Uncharacterised protein family UPF0150
CIGNPGHA_01659	3.89e-68	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
CIGNPGHA_01660	1.47e-07	-	-	-	L	-	-	-	Integrase
CIGNPGHA_01662	7.21e-08	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
CIGNPGHA_01663	0.0	-	1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31	-	Q	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	ko00000,ko00001,ko01000	Flavin containing amine oxidoreductase
CIGNPGHA_01664	1.36e-208	crtM	2.5.1.32, 2.5.1.99	-	I	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Squalene/phytoene synthase
CIGNPGHA_01665	2.15e-77	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
CIGNPGHA_01666	3.68e-104	-	-	-	L	-	-	-	Transposase DDE domain
CIGNPGHA_01667	9.4e-122	-	-	-	L	-	-	-	4.5 Transposon and IS
CIGNPGHA_01668	2.71e-33	-	-	-	L	ko:K07483	-	ko00000	Transposase
CIGNPGHA_01669	6.84e-233	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
CIGNPGHA_01670	2.38e-153	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	COG1136 ABC-type antimicrobial peptide transport system, ATPase component
CIGNPGHA_01671	3.15e-78	-	-	-	S	-	-	-	Bacterial toxin of type II toxin-antitoxin system, YafQ
CIGNPGHA_01672	3.88e-60	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
CIGNPGHA_01673	4.4e-138	-	-	-	L	-	-	-	Integrase
CIGNPGHA_01674	2.08e-60	-	-	-	S	-	-	-	Phage derived protein Gp49-like (DUF891)
CIGNPGHA_01675	3.03e-49	-	-	-	K	-	-	-	sequence-specific DNA binding
CIGNPGHA_01676	3.02e-68	-	-	-	S	-	-	-	Bacterial mobilisation protein (MobC)
CIGNPGHA_01677	3.95e-231	-	-	-	U	-	-	-	Relaxase/Mobilisation nuclease domain
CIGNPGHA_01678	1.91e-91	-	-	-	-	-	-	-	-
CIGNPGHA_01679	3.06e-35	-	-	-	L	ko:K07483	-	ko00000	Homeodomain-like domain
CIGNPGHA_01680	3.7e-164	-	-	-	L	ko:K07498	-	ko00000	Transposase IS66 family
CIGNPGHA_01681	9.84e-58	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
CIGNPGHA_01682	6.62e-105	-	-	-	S	-	-	-	GtrA-like protein
CIGNPGHA_01683	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
CIGNPGHA_01684	7.48e-147	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
CIGNPGHA_01685	2.77e-290	-	-	-	S	ko:K01421	-	ko00000	ABC-2 family transporter protein
CIGNPGHA_01686	8.55e-186	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
CIGNPGHA_01687	2.4e-71	-	-	-	S	-	-	-	protein encoded in hypervariable junctions of pilus gene clusters
CIGNPGHA_01688	4.51e-109	-	-	-	-	-	-	-	-
CIGNPGHA_01689	1.37e-128	-	-	-	S	ko:K09962	-	ko00000	Nucleotidyltransferase
CIGNPGHA_01690	1.71e-110	-	-	-	S	-	-	-	Protein of unknown function (DUF2798)
CIGNPGHA_01691	2.19e-75	yuxO	-	-	Q	-	-	-	Thioesterase superfamily
CIGNPGHA_01692	6.68e-199	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CIGNPGHA_01693	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
CIGNPGHA_01694	1.44e-122	-	-	-	S	-	-	-	Protein of unknown function (DUF1097)
CIGNPGHA_01695	1.93e-214	-	-	-	-	-	-	-	-
CIGNPGHA_01696	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CIGNPGHA_01697	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
CIGNPGHA_01698	2.78e-168	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
CIGNPGHA_01699	4.3e-106	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
CIGNPGHA_01700	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
CIGNPGHA_01701	6.58e-175	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Serine aminopeptidase, S33
CIGNPGHA_01702	1.06e-44	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
CIGNPGHA_01703	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
CIGNPGHA_01705	1.89e-316	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
CIGNPGHA_01706	5.46e-179	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
CIGNPGHA_01707	7.88e-287	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
CIGNPGHA_01708	8.53e-245	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
CIGNPGHA_01709	1.99e-237	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
CIGNPGHA_01711	2.33e-137	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
CIGNPGHA_01713	6.3e-161	-	-	-	S	-	-	-	membrane
CIGNPGHA_01714	1.68e-50	-	-	-	-	-	-	-	-
CIGNPGHA_01715	1.19e-173	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
CIGNPGHA_01716	6.12e-156	-	-	-	S	-	-	-	Membrane
CIGNPGHA_01717	0.0	-	-	-	O	-	-	-	Pro-kumamolisin, activation domain
CIGNPGHA_01718	1.36e-213	-	-	-	I	-	-	-	Alpha beta
CIGNPGHA_01719	4.74e-190	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
CIGNPGHA_01720	1.19e-231	-	-	-	D	ko:K06889	-	ko00000	Alpha beta
CIGNPGHA_01721	2.16e-126	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
CIGNPGHA_01722	3.79e-308	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CIGNPGHA_01723	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CIGNPGHA_01724	4.71e-238	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
CIGNPGHA_01725	5.39e-135	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
CIGNPGHA_01726	8.6e-118	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CIGNPGHA_01727	3.88e-240	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CIGNPGHA_01728	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
CIGNPGHA_01729	5.97e-285	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
CIGNPGHA_01730	2.98e-217	ypjC	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CIGNPGHA_01731	4.5e-298	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
CIGNPGHA_01732	1.87e-53	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
CIGNPGHA_01733	1.34e-314	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
CIGNPGHA_01734	2.29e-278	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
CIGNPGHA_01735	9.33e-153	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
CIGNPGHA_01736	4.61e-63	-	-	-	M	-	-	-	Lysin motif
CIGNPGHA_01737	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
CIGNPGHA_01738	1.4e-238	-	-	-	S	-	-	-	Helix-turn-helix domain
CIGNPGHA_01739	4.5e-121	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CIGNPGHA_01740	2.58e-166	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
CIGNPGHA_01741	1.7e-133	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CIGNPGHA_01742	4.42e-170	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CIGNPGHA_01743	7.96e-94	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CIGNPGHA_01744	1.79e-211	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
CIGNPGHA_01745	3.1e-214	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
CIGNPGHA_01746	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
CIGNPGHA_01747	2.65e-160	tal2	2.2.1.2	-	H	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase/Fructose-6-phosphate aldolase
CIGNPGHA_01748	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
CIGNPGHA_01749	0.0	clpB	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
CIGNPGHA_01750	3.57e-301	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
CIGNPGHA_01751	1.52e-197	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CIGNPGHA_01752	1.14e-162	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
CIGNPGHA_01753	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
CIGNPGHA_01754	1.11e-111	-	-	-	K	-	-	-	Transcriptional regulator
CIGNPGHA_01755	9.66e-252	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
CIGNPGHA_01756	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
CIGNPGHA_01757	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
CIGNPGHA_01758	7.13e-227	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
CIGNPGHA_01759	3.06e-193	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
CIGNPGHA_01760	1.27e-217	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CIGNPGHA_01761	2.74e-81	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
CIGNPGHA_01762	1.22e-112	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CIGNPGHA_01763	2.8e-230	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
CIGNPGHA_01764	1.72e-94	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
CIGNPGHA_01765	1.27e-79	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
CIGNPGHA_01766	4.75e-245	qor	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
CIGNPGHA_01767	2.21e-30	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
CIGNPGHA_01768	1.69e-193	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
CIGNPGHA_01769	6.04e-220	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CIGNPGHA_01770	3.08e-308	-	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	glycerophosphotransferase
CIGNPGHA_01771	1.84e-194	tagG	-	-	U	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
CIGNPGHA_01772	9.98e-262	tagB	2.7.8.44	-	M	ko:K21285	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
CIGNPGHA_01773	1.65e-208	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CIGNPGHA_01774	3.57e-125	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CIGNPGHA_01775	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
CIGNPGHA_01776	1.89e-312	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
CIGNPGHA_01777	2.71e-125	-	-	-	-	-	-	-	-
CIGNPGHA_01778	2.24e-202	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	N-acetylmuramoyl-L-alanine amidase
CIGNPGHA_01779	1.67e-207	-	-	-	G	-	-	-	Fructosamine kinase
CIGNPGHA_01780	1.83e-148	-	-	-	S	-	-	-	HAD-hyrolase-like
CIGNPGHA_01781	1.21e-98	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
CIGNPGHA_01782	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CIGNPGHA_01783	1.6e-79	-	-	-	-	-	-	-	-
CIGNPGHA_01784	8.59e-170	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
CIGNPGHA_01785	5.23e-229	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
CIGNPGHA_01786	1.79e-71	-	-	-	-	-	-	-	-
CIGNPGHA_01787	2.33e-57	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
CIGNPGHA_01788	6.81e-83	-	-	-	-	-	-	-	-
CIGNPGHA_01790	1.02e-50	-	-	-	K	-	-	-	transcriptional regulator
CIGNPGHA_01791	1.82e-119	-	-	-	-	-	-	-	-
CIGNPGHA_01792	8e-45	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
CIGNPGHA_01793	2.9e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CIGNPGHA_01794	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CIGNPGHA_01795	2.22e-206	-	-	-	S	-	-	-	Tetratricopeptide repeat
CIGNPGHA_01796	9.55e-286	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CIGNPGHA_01797	1.02e-298	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
CIGNPGHA_01798	5.91e-298	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CIGNPGHA_01799	3.22e-141	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
CIGNPGHA_01800	4.51e-69	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
CIGNPGHA_01801	1.21e-22	-	-	-	-	-	-	-	-
CIGNPGHA_01802	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
CIGNPGHA_01803	3.98e-314	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CIGNPGHA_01806	4.08e-62	-	-	-	-	-	-	-	-
CIGNPGHA_01807	1.1e-116	-	-	-	V	-	-	-	VanZ like family
CIGNPGHA_01808	2.39e-108	ohrR	-	-	K	-	-	-	Transcriptional regulator
CIGNPGHA_01809	4.3e-158	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
CIGNPGHA_01810	3.58e-51	-	-	-	-	-	-	-	-
CIGNPGHA_01811	5.62e-226	-	1.1.1.26	-	CH	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CIGNPGHA_01812	0.0	trePP	2.4.1.216, 2.4.1.8	GH65	G	ko:K00691,ko:K03731	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65 central catalytic domain
CIGNPGHA_01813	2.13e-152	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
CIGNPGHA_01814	7.76e-185	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
CIGNPGHA_01815	1.03e-155	dgk2	-	-	F	-	-	-	Deoxynucleoside kinase
CIGNPGHA_01816	1.15e-73	XK27_08430	-	-	S	-	-	-	Staphylococcal protein of unknown function (DUF960)
CIGNPGHA_01817	0.0	mdr	-	-	EGP	-	-	-	Major Facilitator
CIGNPGHA_01818	6.49e-70	-	-	-	-	-	-	-	-
CIGNPGHA_01819	1.24e-156	-	-	-	P	ko:K01990	-	ko00000,ko00002,ko02000	ABC-type multidrug transport system ATPase component
CIGNPGHA_01820	8.42e-188	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
CIGNPGHA_01821	1.03e-66	-	-	-	-	-	-	-	-
CIGNPGHA_01822	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
CIGNPGHA_01823	4.84e-161	-	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	pseudouridine synthase activity
CIGNPGHA_01824	2.12e-188	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CIGNPGHA_01825	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
CIGNPGHA_01826	3.73e-110	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
CIGNPGHA_01827	9.26e-52	ald	1.4.1.1	-	C	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
CIGNPGHA_01828	2.14e-188	ald	1.4.1.1	-	C	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
CIGNPGHA_01829	1.97e-311	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
CIGNPGHA_01830	2.71e-72	-	-	-	S	-	-	-	Small secreted protein
CIGNPGHA_01831	2.29e-74	ytpP	-	-	CO	-	-	-	Thioredoxin
CIGNPGHA_01832	9.43e-146	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
CIGNPGHA_01833	1.86e-193	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CIGNPGHA_01834	3.23e-58	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
CIGNPGHA_01835	2.91e-180	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CIGNPGHA_01836	8.56e-119	-	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
CIGNPGHA_01837	4.2e-88	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
CIGNPGHA_01838	6.88e-257	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CIGNPGHA_01839	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
CIGNPGHA_01840	7.58e-267	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CIGNPGHA_01841	5.67e-155	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
CIGNPGHA_01842	2.72e-92	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
CIGNPGHA_01843	8.94e-75	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
CIGNPGHA_01844	0.0	-	-	-	S	-	-	-	membrane
CIGNPGHA_01863	1.18e-297	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
CIGNPGHA_01864	4.94e-119	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
CIGNPGHA_01865	1.76e-176	yhfI	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
CIGNPGHA_01866	1.47e-91	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
CIGNPGHA_01867	7.66e-166	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
CIGNPGHA_01868	6.02e-132	-	-	-	T	-	-	-	EAL domain
CIGNPGHA_01869	2.74e-117	-	-	-	-	-	-	-	-
CIGNPGHA_01870	9.4e-313	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
CIGNPGHA_01872	3.94e-133	ytqB	-	-	J	-	-	-	Putative rRNA methylase
CIGNPGHA_01873	2.71e-150	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
CIGNPGHA_01874	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
CIGNPGHA_01875	2.3e-96	-	-	-	P	-	-	-	ArsC family
CIGNPGHA_01876	4.49e-185	lytE	-	-	M	-	-	-	NlpC/P60 family
CIGNPGHA_01877	4.34e-201	-	-	-	K	-	-	-	acetyltransferase
CIGNPGHA_01878	0.0	-	-	-	E	-	-	-	dipeptidase activity
CIGNPGHA_01879	1.69e-88	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
CIGNPGHA_01880	1.2e-65	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
CIGNPGHA_01881	1.81e-159	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
CIGNPGHA_01882	7.05e-171	fabG1	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CIGNPGHA_01883	2.81e-197	-	-	-	GM	-	-	-	NmrA-like family
CIGNPGHA_01884	8.91e-94	-	-	-	K	-	-	-	Transcriptional regulator
CIGNPGHA_01885	0.0	tagB	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	glycerophosphotransferase
CIGNPGHA_01886	2.12e-93	-	-	-	-	-	-	-	-
CIGNPGHA_01887	2.35e-94	-	-	-	-	-	-	-	-
CIGNPGHA_01888	5.61e-82	ytcD	-	-	K	-	-	-	Transcriptional regulator, HxlR family
CIGNPGHA_01889	1.46e-64	-	-	-	-	-	-	-	-
CIGNPGHA_01891	2.09e-30	-	-	-	-	-	-	-	-
CIGNPGHA_01892	4.37e-79	-	-	-	S	-	-	-	Bacteriophage holin family
CIGNPGHA_01894	2.69e-255	lysA2	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
CIGNPGHA_01898	8.66e-13	-	-	-	-	-	-	-	-
CIGNPGHA_01899	0.0	rafA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
CIGNPGHA_01900	6.04e-94	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
CIGNPGHA_01901	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
CIGNPGHA_01902	0.0	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
CIGNPGHA_01903	5.2e-78	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
CIGNPGHA_01904	6.38e-42	-	2.3.1.79	-	M	ko:K00661	-	ko00000,ko01000	Glycosyltransferase Family 4
CIGNPGHA_01905	9.56e-155	-	-	-	S	-	-	-	Polysaccharide biosynthesis protein
CIGNPGHA_01906	8.92e-59	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
CIGNPGHA_01907	5.53e-34	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
CIGNPGHA_01908	4.48e-100	-	-	-	M	-	-	-	Glycosyl transferases group 1
CIGNPGHA_01910	1.76e-43	-	-	-	S	-	-	-	Polysaccharide pyruvyl transferase
CIGNPGHA_01911	7.55e-126	-	-	-	M	-	-	-	Glycosyl transferase 4-like
CIGNPGHA_01913	3.69e-189	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
CIGNPGHA_01914	1.73e-77	-	-	-	S	-	-	-	Family of unknown function (DUF5388)
CIGNPGHA_01915	1.23e-53	-	-	-	-	-	-	-	-
CIGNPGHA_01916	4.58e-91	-	-	-	L	-	-	-	Integrase
CIGNPGHA_01920	2.17e-125	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
CIGNPGHA_01922	1.8e-201	-	-	-	S	-	-	-	Helix-turn-helix domain
CIGNPGHA_01923	2.46e-70	-	-	-	-	-	-	-	-
CIGNPGHA_01924	2.17e-248	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
CIGNPGHA_01925	4.22e-41	-	-	-	-	-	-	-	-
CIGNPGHA_01926	0.0	traI	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
CIGNPGHA_01927	1.55e-07	traI	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
CIGNPGHA_01928	0.0	traA	-	-	L	-	-	-	MobA MobL family protein
CIGNPGHA_01929	1.69e-37	-	-	-	-	-	-	-	-
CIGNPGHA_01930	3.47e-54	-	-	-	-	-	-	-	-
CIGNPGHA_01931	9.37e-159	-	-	-	S	-	-	-	Fic/DOC family
CIGNPGHA_01932	2.34e-59	repA	-	-	S	-	-	-	Replication initiator protein A
CIGNPGHA_01934	6.84e-184	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
CIGNPGHA_01935	2.03e-31	-	-	-	S	-	-	-	Family of unknown function (DUF5388)
CIGNPGHA_01936	3.48e-210	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
CIGNPGHA_01937	9.91e-241	lplL	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Bacterial lipoate protein ligase C-terminus
CIGNPGHA_01938	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
CIGNPGHA_01939	1.27e-250	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
CIGNPGHA_01940	1.68e-103	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
CIGNPGHA_01941	1.58e-281	ribA	3.5.4.25, 4.1.99.12	-	H	ko:K02858,ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
CIGNPGHA_01942	1.57e-134	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
CIGNPGHA_01943	1.79e-250	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CIGNPGHA_01944	2.3e-150	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
CIGNPGHA_01945	3.64e-306	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
CIGNPGHA_01946	5.05e-153	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
CIGNPGHA_01947	6.61e-54	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
CIGNPGHA_01948	3.52e-83	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
CIGNPGHA_01949	6.51e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CIGNPGHA_01950	1.64e-195	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
CIGNPGHA_01951	2.29e-182	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CIGNPGHA_01952	3.08e-208	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CIGNPGHA_01953	4.65e-193	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CIGNPGHA_01954	6.64e-82	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
CIGNPGHA_01955	2.1e-219	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CIGNPGHA_01956	6.34e-81	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CIGNPGHA_01957	2.37e-79	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CIGNPGHA_01958	2.92e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CIGNPGHA_01959	3.43e-156	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
CIGNPGHA_01960	1.3e-301	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
CIGNPGHA_01961	1.95e-89	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
CIGNPGHA_01962	1.2e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
CIGNPGHA_01963	3.46e-110	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CIGNPGHA_01964	8.69e-76	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CIGNPGHA_01965	1.44e-121	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CIGNPGHA_01966	3.78e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CIGNPGHA_01967	3.53e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CIGNPGHA_01968	4.1e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CIGNPGHA_01969	1.04e-78	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CIGNPGHA_01970	3.69e-54	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CIGNPGHA_01971	3.87e-34	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
CIGNPGHA_01972	3.95e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CIGNPGHA_01973	1.63e-154	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CIGNPGHA_01974	9.77e-73	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CIGNPGHA_01975	7.56e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CIGNPGHA_01976	2.32e-199	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CIGNPGHA_01977	4.65e-58	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
CIGNPGHA_01978	6.37e-137	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
CIGNPGHA_01979	1.19e-150	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CIGNPGHA_01980	4.46e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
CIGNPGHA_01981	5.98e-242	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
CIGNPGHA_01982	7.85e-28	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
CIGNPGHA_01983	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CIGNPGHA_01984	5.89e-108	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
CIGNPGHA_01985	1.46e-92	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CIGNPGHA_01986	1.29e-149	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
CIGNPGHA_01987	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CIGNPGHA_01988	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CIGNPGHA_01989	3.87e-135	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
CIGNPGHA_01990	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
CIGNPGHA_01991	2.31e-100	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
CIGNPGHA_02000	3.26e-277	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CIGNPGHA_02001	1.4e-146	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
CIGNPGHA_02002	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
CIGNPGHA_02004	3.72e-196	-	-	-	I	-	-	-	alpha/beta hydrolase fold
CIGNPGHA_02005	2.5e-155	-	-	-	I	-	-	-	phosphatase
CIGNPGHA_02006	1.36e-96	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
CIGNPGHA_02007	4.22e-167	-	-	-	S	-	-	-	Putative threonine/serine exporter
CIGNPGHA_02008	1.46e-155	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
CIGNPGHA_02009	4.51e-205	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
CIGNPGHA_02010	2.03e-130	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
CIGNPGHA_02011	7.65e-101	-	-	-	K	-	-	-	MerR HTH family regulatory protein
CIGNPGHA_02012	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
CIGNPGHA_02013	4.36e-154	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
CIGNPGHA_02014	5.16e-50	-	-	-	K	-	-	-	MerR HTH family regulatory protein
CIGNPGHA_02015	1.68e-139	azlC	-	-	E	-	-	-	branched-chain amino acid
CIGNPGHA_02016	3.39e-67	azlD	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
CIGNPGHA_02017	2.12e-222	-	-	-	-	-	-	-	-
CIGNPGHA_02019	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CIGNPGHA_02020	0.0	-	4.1.1.15, 4.1.2.27	-	E	ko:K01580,ko:K01634	ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940	ko00000,ko00001,ko00002,ko01000	Belongs to the group II decarboxylase family
CIGNPGHA_02021	5.03e-74	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	amino acid
CIGNPGHA_02022	6.38e-258	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	amino acid
CIGNPGHA_02023	1.31e-135	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
CIGNPGHA_02024	1.38e-229	-	-	-	C	-	-	-	nadph quinone reductase
CIGNPGHA_02025	1.55e-128	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
CIGNPGHA_02028	7.3e-268	-	-	-	E	-	-	-	Major Facilitator Superfamily
CIGNPGHA_02029	1.27e-134	-	-	-	S	ko:K06919	-	ko00000	Phage plasmid primase, P4
CIGNPGHA_02030	2.27e-119	-	-	-	L	-	-	-	Bifunctional DNA primase/polymerase, N-terminal
CIGNPGHA_02035	7.19e-11	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
CIGNPGHA_02036	2.32e-260	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
CIGNPGHA_02039	1.87e-126	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
CIGNPGHA_02040	2.2e-105	tspO	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	TspO/MBR family
CIGNPGHA_02041	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
CIGNPGHA_02042	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
CIGNPGHA_02043	4.4e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
CIGNPGHA_02044	1.09e-118	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CIGNPGHA_02045	3.64e-150	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
CIGNPGHA_02046	9.85e-49	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
CIGNPGHA_02047	3.99e-232	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
CIGNPGHA_02048	1.11e-92	yqhL	-	-	P	-	-	-	Rhodanese-like protein
CIGNPGHA_02049	1.23e-32	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
CIGNPGHA_02050	2.31e-179	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
CIGNPGHA_02051	7.04e-218	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CIGNPGHA_02052	7.74e-86	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	Transcriptional regulator
CIGNPGHA_02053	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
CIGNPGHA_02054	7.08e-76	melB	-	-	G	-	-	-	symporter
CIGNPGHA_02055	1.14e-224	araR	-	-	K	ko:K02103	-	ko00000,ko03000	Transcriptional regulator
CIGNPGHA_02056	4.34e-186	-	-	-	K	-	-	-	transcriptional regulator, ArsR family
CIGNPGHA_02057	1.43e-256	abf	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 43 family
CIGNPGHA_02058	9.19e-303	lacY	-	-	G	ko:K02532	-	ko00000,ko02000	Oligosaccharide H symporter
CIGNPGHA_02059	0.0	abfA	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	Alpha-L-arabinofuranosidase C-terminus
CIGNPGHA_02060	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
CIGNPGHA_02061	1.56e-93	-	-	-	K	-	-	-	Transcriptional regulator
CIGNPGHA_02062	5.06e-298	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
CIGNPGHA_02063	9.73e-275	-	-	-	EGP	-	-	-	Transmembrane secretion effector
CIGNPGHA_02064	5.81e-92	-	-	-	-	-	-	-	-
CIGNPGHA_02065	1.15e-115	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
CIGNPGHA_02066	3.42e-132	-	-	-	L	-	-	-	PFAM Integrase catalytic region
CIGNPGHA_02067	4.05e-07	-	-	-	L	ko:K07483,ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Helix-turn-helix domain
CIGNPGHA_02068	5.39e-111	nimA	-	-	S	ko:K07005	-	ko00000	resistance protein
CIGNPGHA_02069	1.26e-137	-	-	-	K	ko:K06977	-	ko00000	acetyltransferase
CIGNPGHA_02070	2.05e-181	yejC	-	-	S	-	-	-	Protein of unknown function (DUF1003)
CIGNPGHA_02071	6.49e-212	yjbO	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
CIGNPGHA_02072	5.12e-71	-	-	-	S	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	Glycine cleavage H-protein
CIGNPGHA_02076	9.4e-45	-	-	-	-	-	-	-	-
CIGNPGHA_02077	1.9e-43	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
CIGNPGHA_02078	1.72e-259	-	-	-	S	ko:K06904	-	ko00000	Caudovirus prohead serine protease
CIGNPGHA_02079	8.18e-245	-	-	-	S	-	-	-	Phage portal protein
CIGNPGHA_02081	0.0	terL	-	-	S	-	-	-	overlaps another CDS with the same product name
CIGNPGHA_02082	3.81e-100	-	-	-	L	-	-	-	overlaps another CDS with the same product name
CIGNPGHA_02083	5.17e-71	-	-	-	L	-	-	-	HNH endonuclease
CIGNPGHA_02086	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
CIGNPGHA_02087	1.11e-32	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
CIGNPGHA_02088	0.0	dld	1.1.5.12	-	C	ko:K03777	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	D-lactate dehydrogenase, membrane binding
CIGNPGHA_02089	1.31e-127	tnpR1	-	-	L	-	-	-	Resolvase, N terminal domain
CIGNPGHA_02090	0.0	-	-	-	EGP	-	-	-	Major Facilitator
CIGNPGHA_02092	1.55e-275	arcT	-	-	E	-	-	-	Aminotransferase
CIGNPGHA_02093	0.0	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
CIGNPGHA_02094	2.48e-252	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CIGNPGHA_02095	1.15e-300	arcA	3.5.3.6	-	E	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	ko00000,ko00001,ko01000	Arginine
CIGNPGHA_02096	0.0	-	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
CIGNPGHA_02097	1.45e-296	ycbA	2.7.13.3	-	T	ko:K07706,ko:K07717	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	histidine kinase DNA gyrase B
CIGNPGHA_02098	4.46e-35	-	-	-	-	-	-	-	-
CIGNPGHA_02105	2.19e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF3102)
CIGNPGHA_02106	7.38e-133	repE	-	-	K	-	-	-	Primase C terminal 1 (PriCT-1)
CIGNPGHA_02107	3.66e-123	-	-	-	D	-	-	-	Cellulose biosynthesis protein BcsQ
CIGNPGHA_02108	1.29e-59	-	-	-	-	-	-	-	-
CIGNPGHA_02109	1.36e-119	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
CIGNPGHA_02110	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
CIGNPGHA_02111	5.47e-178	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
CIGNPGHA_02112	0.0	araB	2.7.1.16	-	G	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	carbohydrate kinase FGGY
CIGNPGHA_02113	0.0	-	-	-	-	-	-	-	-
CIGNPGHA_02114	9.06e-167	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
CIGNPGHA_02115	4.38e-74	-	-	-	G	-	-	-	symporter
CIGNPGHA_02117	5.2e-108	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CIGNPGHA_02118	4.64e-271	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
CIGNPGHA_02119	2.33e-200	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
CIGNPGHA_02120	1.09e-189	yycI	-	-	S	-	-	-	YycH protein
CIGNPGHA_02121	4.78e-307	yycH	-	-	S	-	-	-	YycH protein
CIGNPGHA_02122	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
CIGNPGHA_02123	1.19e-170	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
CIGNPGHA_02125	4.5e-144	-	-	-	E	-	-	-	Matrixin
CIGNPGHA_02126	9.34e-49	-	-	-	-	-	-	-	-
CIGNPGHA_02127	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
CIGNPGHA_02128	1.96e-36	-	-	-	-	-	-	-	-
CIGNPGHA_02129	1.43e-267	yttB	-	-	EGP	-	-	-	Major Facilitator
CIGNPGHA_02130	7.83e-128	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
CIGNPGHA_02131	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
CIGNPGHA_02134	5.23e-91	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
CIGNPGHA_02135	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
CIGNPGHA_02136	4.07e-52	-	-	-	S	-	-	-	response to heat
CIGNPGHA_02137	8.93e-130	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
CIGNPGHA_02138	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
CIGNPGHA_02139	1.87e-291	-	-	-	Q	-	-	-	Imidazolonepropionase and related amidohydrolases
CIGNPGHA_02140	1.38e-179	-	-	-	-	-	-	-	-
CIGNPGHA_02141	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
CIGNPGHA_02142	6.05e-293	-	-	-	Q	-	-	-	Imidazolonepropionase and related amidohydrolases
CIGNPGHA_02143	1.33e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CIGNPGHA_02144	5.15e-104	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
CIGNPGHA_02145	7.86e-65	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
CIGNPGHA_02146	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CIGNPGHA_02147	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CIGNPGHA_02148	2.66e-270	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CIGNPGHA_02149	9.18e-49	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
CIGNPGHA_02150	1.93e-265	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
CIGNPGHA_02151	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CIGNPGHA_02152	1.61e-20	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
CIGNPGHA_02153	9.04e-78	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
CIGNPGHA_02154	1.67e-185	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CIGNPGHA_02155	2.25e-149	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
CIGNPGHA_02156	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CIGNPGHA_02157	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
CIGNPGHA_02158	4.46e-81	-	-	-	-	-	-	-	-
CIGNPGHA_02159	4.81e-50	-	-	-	-	-	-	-	-
CIGNPGHA_02160	1.62e-158	yfnB	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	HAD-hyrolase-like
CIGNPGHA_02161	2.62e-49	-	-	-	-	-	-	-	-
CIGNPGHA_02162	1.34e-312	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
CIGNPGHA_02163	2.68e-142	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
CIGNPGHA_02164	4.33e-127	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
CIGNPGHA_02165	1.45e-119	ykhA	3.1.2.20	-	I	ko:K01073	-	ko00000,ko01000	Thioesterase superfamily
CIGNPGHA_02166	8.1e-281	-	-	-	S	-	-	-	module of peptide synthetase
CIGNPGHA_02167	3.56e-275	tcaB	-	-	EGP	ko:K07552	-	ko00000,ko02000	Drug resistance transporter Bcr CflA subfamily
CIGNPGHA_02168	3.92e-141	sip3	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
CIGNPGHA_02169	7.4e-98	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
CIGNPGHA_02170	5.95e-105	-	-	-	K	-	-	-	LysR substrate binding domain
CIGNPGHA_02171	1.4e-233	-	-	-	C	-	-	-	Oxidoreductase
CIGNPGHA_02172	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
CIGNPGHA_02173	3.68e-144	nt5e	3.1.3.18	-	L	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	haloacid dehalogenase-like hydrolase
CIGNPGHA_02174	3.28e-63	-	-	-	-	-	-	-	-
CIGNPGHA_02176	3.71e-147	lacA	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
CIGNPGHA_02177	4.45e-151	-	-	-	-	-	-	-	-
CIGNPGHA_02178	8.42e-149	cah	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	Eukaryotic-type carbonic anhydrase
CIGNPGHA_02179	3.88e-285	-	-	-	LO	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
CIGNPGHA_02180	7.02e-36	-	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional
CIGNPGHA_02181	6.68e-86	-	-	-	-	-	-	-	-
CIGNPGHA_02182	0.0	-	-	-	M	-	-	-	MucBP domain
CIGNPGHA_02183	2.56e-119	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
CIGNPGHA_02184	2.09e-146	-	-	-	S	-	-	-	VIT family
CIGNPGHA_02185	1.12e-153	-	-	-	S	-	-	-	membrane
CIGNPGHA_02186	0.0	ybeC	-	-	E	-	-	-	amino acid
CIGNPGHA_02187	3.62e-105	yoaA	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CIGNPGHA_02188	2.9e-253	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
CIGNPGHA_02190	4.7e-50	-	-	-	KLT	-	-	-	Protein kinase domain
CIGNPGHA_02191	1.49e-138	-	-	-	U	ko:K03457	-	ko00000	Belongs to the purine-cytosine permease (2.A.39) family
CIGNPGHA_02192	4.4e-47	-	-	-	-	-	-	-	-
CIGNPGHA_02193	0.0	-	-	-	K	-	-	-	Mga helix-turn-helix domain
CIGNPGHA_02194	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
CIGNPGHA_02195	4.24e-78	-	-	-	K	-	-	-	Winged helix DNA-binding domain
CIGNPGHA_02196	1.72e-40	-	-	-	-	-	-	-	-
CIGNPGHA_02197	3.1e-305	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
CIGNPGHA_02198	1.86e-306	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CIGNPGHA_02199	0.0	xynB	3.2.1.37	GH43	G	ko:K01198	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
CIGNPGHA_02200	0.0	-	-	-	G	ko:K03292	-	ko00000	MFS/sugar transport protein
CIGNPGHA_02201	3.23e-195	rhaS2	-	-	K	-	-	-	Transcriptional regulator, AraC family
CIGNPGHA_02202	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CIGNPGHA_02203	1.75e-29	-	-	-	-	-	-	-	-
CIGNPGHA_02204	1.89e-190	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
CIGNPGHA_02205	8.3e-117	-	-	-	-	-	-	-	-
CIGNPGHA_02206	9.26e-200	-	-	-	L	-	-	-	Initiator Replication protein
CIGNPGHA_02207	1.57e-67	-	-	-	-	-	-	-	-
CIGNPGHA_02208	1.57e-86	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
CIGNPGHA_02209	7.2e-113	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
CIGNPGHA_02210	5.86e-61	-	-	-	L	ko:K07483	-	ko00000	Transposase
CIGNPGHA_02212	9.35e-117	-	-	-	M	-	-	-	Glycosyl transferase family group 2
CIGNPGHA_02213	3.65e-175	-	-	-	K	-	-	-	Helix-turn-helix domain
CIGNPGHA_02214	3.2e-76	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
CIGNPGHA_02215	3.16e-59	-	-	-	T	ko:K07172	-	ko00000,ko02048	Antidote-toxin recognition MazE, bacterial antitoxin
CIGNPGHA_02216	7.6e-139	-	-	-	L	-	-	-	Integrase
CIGNPGHA_02217	3.03e-40	-	-	-	-	-	-	-	-
CIGNPGHA_02218	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
CIGNPGHA_02219	2.77e-94	usp1	-	-	T	-	-	-	Universal stress protein family
CIGNPGHA_02220	4.7e-157	-	-	-	K	ko:K03709	-	ko00000,ko03000	Helix-turn-helix diphteria tox regulatory element
CIGNPGHA_02221	1.94e-124	-	-	-	P	-	-	-	Cadmium resistance transporter
CIGNPGHA_02222	1.92e-118	-	-	-	-	-	-	-	-
CIGNPGHA_02223	1.06e-95	-	-	-	-	-	-	-	-
CIGNPGHA_02228	3.84e-188	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
CIGNPGHA_02229	0.0	yclK	-	-	T	-	-	-	Histidine kinase
CIGNPGHA_02230	8.88e-268	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	S-adenosylmethionine-dependent methyltransferase
CIGNPGHA_02231	8.7e-198	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
CIGNPGHA_02232	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
CIGNPGHA_02233	4.64e-124	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
CIGNPGHA_02234	0.0	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
CIGNPGHA_02235	3.02e-124	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
CIGNPGHA_02236	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CIGNPGHA_02237	7.85e-209	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CIGNPGHA_02238	1.22e-246	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CIGNPGHA_02239	7.92e-145	-	-	-	K	-	-	-	transcriptional regulator, ArsR family
CIGNPGHA_02240	2.68e-42	-	-	-	L	-	-	-	Helix-turn-helix domain
CIGNPGHA_02241	7.45e-47	-	-	-	L	-	-	-	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CIGNPGHA_02242	6.06e-09	-	-	-	S	-	-	-	Putative Holin-like Toxin (Hol-Tox)
CIGNPGHA_02243	7.28e-212	-	-	-	-	-	-	-	-
CIGNPGHA_02244	1.4e-137	tnpR	-	-	L	-	-	-	Resolvase, N terminal domain
CIGNPGHA_02245	8.85e-102	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
CIGNPGHA_02246	2.38e-132	yvbG	-	-	U	ko:K05595	-	ko00000,ko02000	MarC family integral membrane protein
CIGNPGHA_02247	4.1e-105	nrdI	-	-	F	ko:K03647	-	ko00000	NrdI Flavodoxin like
CIGNPGHA_02248	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CIGNPGHA_02249	5.59e-220	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Ribonucleotide reductase, small chain
CIGNPGHA_02250	1.34e-231	-	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Ribonucleotide reductase, small chain
CIGNPGHA_02251	1.98e-137	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
CIGNPGHA_02252	7.08e-63	-	-	-	L	-	-	-	Resolvase, N terminal domain
CIGNPGHA_02253	4.72e-165	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
CIGNPGHA_02254	5.33e-63	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
CIGNPGHA_02256	3.37e-110	ykuL	-	-	S	-	-	-	(CBS) domain
CIGNPGHA_02257	1.41e-125	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
CIGNPGHA_02258	5.97e-138	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CIGNPGHA_02259	7.98e-188	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
CIGNPGHA_02260	4.87e-118	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
CIGNPGHA_02261	5.12e-71	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
CIGNPGHA_02262	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
CIGNPGHA_02263	5.2e-115	cvpA	-	-	S	-	-	-	Colicin V production protein
CIGNPGHA_02264	1.62e-53	-	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
CIGNPGHA_02265	2.47e-68	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
CIGNPGHA_02266	7.07e-97	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CIGNPGHA_02267	1.94e-59	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
CIGNPGHA_02268	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CIGNPGHA_02269	0.0	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
CIGNPGHA_02270	5.26e-230	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
CIGNPGHA_02271	3.87e-231	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CIGNPGHA_02272	7.43e-46	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
CIGNPGHA_02273	6.46e-290	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
CIGNPGHA_02274	3.96e-254	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CIGNPGHA_02275	9.56e-243	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
CIGNPGHA_02276	1.07e-137	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
CIGNPGHA_02277	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CIGNPGHA_02278	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CIGNPGHA_02279	8.08e-191	ymdB	-	-	S	ko:K02029,ko:K02030,ko:K09769	-	ko00000,ko00002,ko02000	YmdB-like protein
CIGNPGHA_02280	6.75e-314	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
CIGNPGHA_02282	3.9e-248	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CIGNPGHA_02283	6.05e-290	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
CIGNPGHA_02284	4.55e-131	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CIGNPGHA_02285	2.57e-141	ymfM	-	-	S	ko:K15539	-	ko00000	Domain of unknown function (DUF4115)
CIGNPGHA_02286	1.89e-311	ymfH	-	-	S	-	-	-	Peptidase M16
CIGNPGHA_02287	9.21e-304	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
CIGNPGHA_02288	1.85e-204	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
CIGNPGHA_02289	8.68e-121	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
CIGNPGHA_02290	5.65e-143	-	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter permease
CIGNPGHA_02291	1.57e-190	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
CIGNPGHA_02292	1.18e-149	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
CIGNPGHA_02293	3.16e-119	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
CIGNPGHA_02294	5.96e-182	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
CIGNPGHA_02295	1.71e-218	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
CIGNPGHA_02296	3.27e-150	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
CIGNPGHA_02297	4.82e-315	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
CIGNPGHA_02298	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
CIGNPGHA_02299	5.75e-119	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CIGNPGHA_02300	1.27e-290	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CIGNPGHA_02301	5.63e-275	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
CIGNPGHA_02302	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
CIGNPGHA_02303	7.76e-108	yebR	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
CIGNPGHA_02304	5.1e-140	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CIGNPGHA_02305	6.78e-81	-	-	-	KLT	-	-	-	serine threonine protein kinase
CIGNPGHA_02306	6.01e-147	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
CIGNPGHA_02307	1.3e-104	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
CIGNPGHA_02308	4.23e-306	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
CIGNPGHA_02309	3.68e-55	-	-	-	-	-	-	-	-
CIGNPGHA_02310	2.12e-107	uspA	-	-	T	-	-	-	universal stress protein
CIGNPGHA_02311	5.48e-204	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
CIGNPGHA_02312	1.5e-234	-	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
CIGNPGHA_02313	1.56e-276	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
CIGNPGHA_02314	3.15e-229	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
CIGNPGHA_02315	3.22e-185	-	-	-	O	-	-	-	Band 7 protein
CIGNPGHA_02316	1e-106	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
CIGNPGHA_02317	2.23e-129	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CIGNPGHA_02318	1.6e-98	rppH3	-	-	F	-	-	-	NUDIX domain
CIGNPGHA_02319	5.45e-257	xerS	-	-	L	ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
CIGNPGHA_02320	0.0	-	-	-	-	-	-	-	-
CIGNPGHA_02321	4.15e-170	-	-	-	Q	-	-	-	Methyltransferase domain
CIGNPGHA_02322	1.83e-200	-	-	-	-	-	-	-	-
CIGNPGHA_02323	7.15e-230	-	-	-	-	-	-	-	-
CIGNPGHA_02324	1.05e-124	-	-	-	S	-	-	-	Protein conserved in bacteria
CIGNPGHA_02325	3.43e-123	-	-	-	K	-	-	-	Transcriptional regulator
CIGNPGHA_02326	5.22e-65	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
CIGNPGHA_02327	7.92e-76	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
CIGNPGHA_02328	8.46e-65	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
CIGNPGHA_02329	4.34e-185	-	-	-	-	-	-	-	-
CIGNPGHA_02330	2.11e-108	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
CIGNPGHA_02332	6.13e-258	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
CIGNPGHA_02333	1.15e-163	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
CIGNPGHA_02336	0.0	-	-	-	S	ko:K09955	-	ko00000	Beta-L-arabinofuranosidase, GH127
CIGNPGHA_02337	2.95e-64	-	-	-	K	-	-	-	AraC family transcriptional regulator
CIGNPGHA_02339	4.68e-300	arcA	3.5.3.6	-	E	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	ko00000,ko00001,ko01000	Arginine
CIGNPGHA_02340	2.48e-189	-	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
CIGNPGHA_02341	2.03e-171	-	-	-	S	ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	protein conserved in bacteria
CIGNPGHA_02342	4.25e-128	-	-	-	S	-	-	-	Putative glutamine amidotransferase
CIGNPGHA_02343	9.12e-237	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
CIGNPGHA_02344	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
CIGNPGHA_02345	7.07e-92	ywnA	-	-	K	-	-	-	Transcriptional regulator
CIGNPGHA_02346	2e-61	qorB	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NmrA-like family
CIGNPGHA_02347	1.04e-32	qorB	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NmrA-like family
CIGNPGHA_02349	1.9e-129	-	-	-	S	-	-	-	DJ-1/PfpI family
CIGNPGHA_02350	3.68e-43	-	-	-	S	-	-	-	YjbR
CIGNPGHA_02351	4.95e-248	-	1.1.1.90	-	C	ko:K00055	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Zn-dependent alcohol dehydrogenases, class III
CIGNPGHA_02352	6.38e-192	-	-	-	K	-	-	-	LysR substrate binding domain
CIGNPGHA_02353	3.46e-51	-	-	-	K	-	-	-	MerR, DNA binding
CIGNPGHA_02354	3.32e-74	cadX	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
CIGNPGHA_02355	3.8e-128	cadD	-	-	P	-	-	-	Cadmium resistance transporter
CIGNPGHA_02357	3.21e-150	-	-	-	L	-	-	-	Initiator Replication protein
CIGNPGHA_02358	1.25e-202	-	-	-	U	-	-	-	Relaxase/Mobilisation nuclease domain
CIGNPGHA_02359	2.01e-41	-	-	-	S	-	-	-	Bacterial mobilisation protein (MobC)
CIGNPGHA_02360	1.1e-234	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
CIGNPGHA_02361	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
CIGNPGHA_02362	1.05e-116	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
CIGNPGHA_02363	2.27e-151	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
CIGNPGHA_02364	0.0	-	-	-	-	-	-	-	-
CIGNPGHA_02365	1.54e-177	-	-	-	E	-	-	-	IrrE N-terminal-like domain
CIGNPGHA_02366	4.68e-10	-	-	-	S	-	-	-	Domain of unknown function (DUF4411)
CIGNPGHA_02367	1.41e-205	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
CIGNPGHA_02368	7.85e-242	add	3.5.4.2, 3.5.4.4	-	F	ko:K01488,ko:K02029,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CIGNPGHA_02369	0.0	oatA	-	-	I	-	-	-	Acyltransferase
CIGNPGHA_02370	9.04e-156	-	-	-	-	-	-	-	-
CIGNPGHA_02371	0.0	l1n	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
CIGNPGHA_02372	1.08e-133	-	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
CIGNPGHA_02373	1.38e-89	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
CIGNPGHA_02374	2.11e-49	-	-	-	-	-	-	-	-
CIGNPGHA_02375	4.44e-122	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
CIGNPGHA_02376	1.5e-315	xylP1	-	-	G	ko:K03292	-	ko00000	MFS/sugar transport protein
CIGNPGHA_02377	1.16e-129	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
CIGNPGHA_02378	0.0	uvrA2	-	-	L	-	-	-	ABC transporter
CIGNPGHA_02379	5.02e-87	yodA	-	-	S	-	-	-	Tautomerase enzyme
CIGNPGHA_02380	0.0	-	-	-	-	-	-	-	-
CIGNPGHA_02381	5.73e-300	-	-	-	-	-	-	-	-
CIGNPGHA_02382	3.23e-141	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CIGNPGHA_02383	1.74e-224	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
CIGNPGHA_02384	1.39e-136	opuCB	-	-	E	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
CIGNPGHA_02385	6.99e-199	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
CIGNPGHA_02386	5.69e-56	-	-	-	-	-	-	-	-
CIGNPGHA_02387	4.19e-282	-	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
CIGNPGHA_02388	8.73e-233	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
CIGNPGHA_02389	1.29e-279	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
CIGNPGHA_02390	1.72e-159	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
CIGNPGHA_02391	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CIGNPGHA_02392	1.71e-179	ykoT	-	-	M	-	-	-	Glycosyl transferase family 2
CIGNPGHA_02393	3.13e-31	ykoT	-	-	M	-	-	-	Glycosyl transferase family 2
CIGNPGHA_02394	1.12e-308	-	-	-	M	ko:K07273	-	ko00000	hydrolase, family 25
CIGNPGHA_02395	1.43e-136	-	-	-	-	-	-	-	-
CIGNPGHA_02396	9.86e-264	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
CIGNPGHA_02397	1.17e-265	yclI	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
CIGNPGHA_02398	1.9e-153	vex2	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
CIGNPGHA_02399	0.0	malL	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
CIGNPGHA_02400	3.54e-178	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
CIGNPGHA_02401	3.29e-206	-	-	-	P	-	-	-	CorA-like Mg2+ transporter protein
CIGNPGHA_02402	0.0	pox2	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
CIGNPGHA_02403	3.7e-96	-	-	-	-	-	-	-	-
CIGNPGHA_02404	3.02e-57	-	-	-	-	-	-	-	-
CIGNPGHA_02405	1.03e-314	hpk2	-	-	T	-	-	-	Histidine kinase
CIGNPGHA_02406	2.6e-167	rrp2	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
CIGNPGHA_02407	6.24e-53	-	-	-	-	-	-	-	-
CIGNPGHA_02408	2.61e-148	-	-	-	GM	-	-	-	NAD(P)H-binding
CIGNPGHA_02409	3.79e-291	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
CIGNPGHA_02411	1.25e-119	ogt	2.1.1.63	-	L	ko:K00567	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CIGNPGHA_02412	7.64e-131	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
CIGNPGHA_02413	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
CIGNPGHA_02414	1.36e-128	-	-	-	K	-	-	-	Bacterial transcriptional regulator
CIGNPGHA_02415	5.76e-65	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
CIGNPGHA_02416	2.31e-06	-	-	-	-	-	-	-	-
CIGNPGHA_02417	1.86e-184	kduI	5.3.1.17	-	G	ko:K01815	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
CIGNPGHA_02418	5.12e-177	kduD	1.1.1.127	-	IQ	ko:K00065	ko00040,map00040	ko00000,ko00001,ko01000	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CIGNPGHA_02419	6.39e-164	kdgT	-	-	P	ko:K02526	-	ko00000,ko02000	2-keto-3-deoxygluconate permease
CIGNPGHA_02420	3.21e-139	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	pfkB family carbohydrate kinase
CIGNPGHA_02421	2.71e-103	eda	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	KDPG and KHG aldolase
CIGNPGHA_02422	1.48e-165	-	1.1.1.53	-	IQ	ko:K00038	ko00140,ko01100,map00140,map01100	ko00000,ko00001,ko01000	reductase
CIGNPGHA_02423	1.8e-306	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
CIGNPGHA_02424	1.96e-50	-	-	-	-	-	-	-	-
CIGNPGHA_02428	2.27e-18	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
CIGNPGHA_02429	4.53e-45	-	-	-	-	-	-	-	-
CIGNPGHA_02430	0.0	traI	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
CIGNPGHA_02431	0.0	traA	-	-	L	-	-	-	MobA MobL family protein
CIGNPGHA_02432	4.26e-133	-	-	-	-	-	-	-	-
CIGNPGHA_02433	3.18e-180	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CIGNPGHA_02434	1.62e-227	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
CIGNPGHA_02435	7.73e-109	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
CIGNPGHA_02436	5.48e-114	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
CIGNPGHA_02437	4.56e-244	tas3	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
CIGNPGHA_02441	4.26e-24	-	-	-	K	ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	Transcriptional activator, Rgg GadR MutR family
CIGNPGHA_02442	2.32e-158	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
CIGNPGHA_02443	1.87e-170	-	-	-	-	-	-	-	-
CIGNPGHA_02444	0.0	xpkA	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	XFP C-terminal domain
CIGNPGHA_02445	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
CIGNPGHA_02446	3.18e-246	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
CIGNPGHA_02447	2.22e-15	-	-	-	C	-	-	-	Flavodoxin
CIGNPGHA_02448	2.22e-236	-	-	-	L	-	-	-	PFAM Integrase catalytic region
CIGNPGHA_02449	1.3e-125	gbuC	-	-	E	ko:K02001,ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
CIGNPGHA_02450	4.63e-143	gbuB	-	-	E	ko:K02001	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
CIGNPGHA_02451	2.85e-234	gbuA	3.6.3.32	-	E	ko:K02000	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	glycine betaine
CIGNPGHA_02452	4.42e-248	adhP	1.1.1.1	-	C	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
CIGNPGHA_02453	3.25e-154	csrR	-	-	K	-	-	-	response regulator
CIGNPGHA_02454	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
CIGNPGHA_02455	5.33e-211	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
CIGNPGHA_02456	3.47e-244	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
CIGNPGHA_02457	4.23e-217	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
CIGNPGHA_02458	2.08e-133	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
CIGNPGHA_02459	0.0	-	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	ABC transporter