ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
MKNOAAOH_00001 1.1e-257 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MKNOAAOH_00002 8.98e-202 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MKNOAAOH_00003 4.51e-27 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
MKNOAAOH_00004 1.38e-192 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MKNOAAOH_00005 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MKNOAAOH_00006 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MKNOAAOH_00007 7.37e-60 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
MKNOAAOH_00008 6.48e-89 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MKNOAAOH_00009 3.82e-47 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MKNOAAOH_00010 1.74e-139 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 Dehydrogenase
MKNOAAOH_00011 9.4e-148 - - - S - - - Glycosyl transferase family 2
MKNOAAOH_00012 2.26e-81 - - - D - - - peptidase
MKNOAAOH_00013 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
MKNOAAOH_00014 1.3e-48 - - - S - - - Protein of unknown function (DUF1211)
MKNOAAOH_00016 5.27e-53 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MKNOAAOH_00017 3.25e-307 pox1 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
MKNOAAOH_00018 5.01e-22 yneR - - - - - - -
MKNOAAOH_00019 7.19e-290 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MKNOAAOH_00020 7.54e-284 yxbA 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp enzyme
MKNOAAOH_00021 3.32e-136 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
MKNOAAOH_00022 1.05e-191 - - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
MKNOAAOH_00023 1.12e-11 yobS - - K - - - Bacterial regulatory proteins, tetR family
MKNOAAOH_00024 8.94e-141 - - - U ko:K05340 - ko00000,ko02000 sugar transport
MKNOAAOH_00025 3.74e-212 - - - S - - - Putative threonine/serine exporter
MKNOAAOH_00026 6.27e-90 - - - J - - - Acetyltransferase (GNAT) domain
MKNOAAOH_00027 4.69e-121 yicL - - EG - - - EamA-like transporter family
MKNOAAOH_00028 9.13e-278 pepF - - E - - - Oligopeptidase F
MKNOAAOH_00029 2.04e-137 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
MKNOAAOH_00030 2.01e-224 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
MKNOAAOH_00031 4.63e-175 - 1.1.1.6 - C ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 ko00000,ko00001,ko01000 Iron-containing alcohol dehydrogenase
MKNOAAOH_00032 2.06e-80 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
MKNOAAOH_00033 2.51e-31 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
MKNOAAOH_00035 1.06e-216 - - - S - - - Putative peptidoglycan binding domain
MKNOAAOH_00036 4.68e-41 - - - K - - - Transcriptional regulator, MarR family
MKNOAAOH_00037 2.16e-269 XK27_09600 - - V ko:K06147,ko:K18891 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MKNOAAOH_00038 3.9e-287 XK27_09605 - - V ko:K18892 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter transmembrane region
MKNOAAOH_00040 3.56e-106 - - - S ko:K19175 - ko00000,ko02048 Domain of unknown function DUF87
MKNOAAOH_00042 5.63e-108 yxeH - - S - - - hydrolase
MKNOAAOH_00043 2.43e-151 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
MKNOAAOH_00044 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MKNOAAOH_00045 7.57e-126 yycH - - S - - - YycH protein
MKNOAAOH_00046 3.35e-100 yycI - - S - - - YycH protein
MKNOAAOH_00047 4.78e-41 - - - S - - - YjbR
MKNOAAOH_00048 1.46e-147 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
MKNOAAOH_00049 2.33e-187 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
MKNOAAOH_00050 1.32e-93 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MKNOAAOH_00051 2.65e-52 - - - GM - - - NAD(P)H-binding
MKNOAAOH_00052 3.67e-34 - - - K - - - MarR family transcriptional regulator
MKNOAAOH_00053 5.45e-112 - - - GM - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
MKNOAAOH_00054 7.15e-58 - - - S - - - PD-(D/E)XK nuclease family transposase
MKNOAAOH_00055 5.59e-262 glpT - - G ko:K02445 - ko00000,ko02000 glycerol-3-phosphate transporter
MKNOAAOH_00056 1.72e-38 - - - L ko:K07483,ko:K07497 - ko00000 Helix-turn-helix domain
MKNOAAOH_00057 4.79e-87 - - - L - - - HTH-like domain
MKNOAAOH_00058 4.34e-93 - - - L ko:K07491 - ko00000 PFAM transposase IS200-family protein
MKNOAAOH_00059 3.13e-273 - - - L - - - PFAM RNA-directed DNA polymerase (Reverse transcriptase)
MKNOAAOH_00060 3.26e-186 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
MKNOAAOH_00061 1.25e-186 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
MKNOAAOH_00062 1.46e-106 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MKNOAAOH_00063 2.14e-141 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
MKNOAAOH_00064 1.53e-251 gshAB 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
MKNOAAOH_00065 2.65e-35 - - - - - - - -
MKNOAAOH_00066 0.0 clpL - - O ko:K04086 - ko00000,ko03110 C-terminal, D2-small domain, of ClpB protein
MKNOAAOH_00067 7.37e-78 - - - T - - - Universal stress protein family
MKNOAAOH_00069 6.3e-271 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MKNOAAOH_00070 3.5e-214 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
MKNOAAOH_00071 5.34e-31 - - - - - - - -
MKNOAAOH_00072 6.57e-186 scrR - - K ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
MKNOAAOH_00073 1.1e-270 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
MKNOAAOH_00074 0.0 scrA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MKNOAAOH_00075 7.87e-229 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
MKNOAAOH_00076 3.4e-144 ktrB - - P ko:K03498 - ko00000,ko02000 Potassium uptake protein
MKNOAAOH_00077 1.08e-74 - - - P ko:K03499 - ko00000,ko02000 TrkA-N domain
MKNOAAOH_00078 7.12e-68 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
MKNOAAOH_00079 4.49e-57 - - - K - - - helix_turn_helix isocitrate lyase regulation
MKNOAAOH_00080 3.37e-151 - 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MKNOAAOH_00081 5.45e-130 pfoS/R - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
MKNOAAOH_00082 5.71e-28 - - - - - - - -
MKNOAAOH_00083 1.78e-111 - - - S - - - Predicted membrane protein (DUF2207)
MKNOAAOH_00084 3.82e-71 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
MKNOAAOH_00085 1.83e-230 lmrB - - U ko:K18926 - ko00000,ko00002,ko02000 Belongs to the major facilitator superfamily
MKNOAAOH_00086 1.9e-116 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
MKNOAAOH_00087 2.27e-91 - - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
MKNOAAOH_00088 2.35e-76 yceE - - S - - - haloacid dehalogenase-like hydrolase
MKNOAAOH_00089 7.18e-51 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
MKNOAAOH_00090 1.12e-41 - - - S - - - Domain of unknown function (DUF4811)
MKNOAAOH_00091 1.41e-246 ycnB - - U - - - Belongs to the major facilitator superfamily
MKNOAAOH_00092 2.49e-43 - - - K - - - MerR HTH family regulatory protein
MKNOAAOH_00093 1.29e-51 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MKNOAAOH_00094 1.22e-89 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
MKNOAAOH_00095 1.19e-147 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
MKNOAAOH_00096 1.46e-101 yfiK - - KT ko:K02479 - ko00000,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MKNOAAOH_00097 3.34e-122 baeS - - T - - - Histidine kinase
MKNOAAOH_00098 6.18e-101 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 sugar-binding domain protein
MKNOAAOH_00099 3.19e-192 manL 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
MKNOAAOH_00100 1.69e-153 - - - G ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
MKNOAAOH_00101 1.4e-188 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
MKNOAAOH_00102 1.61e-67 - - - S - - - Domain of unknown function (DUF956)
MKNOAAOH_00103 5.58e-93 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
MKNOAAOH_00104 2.89e-164 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MKNOAAOH_00105 8.6e-207 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MKNOAAOH_00106 3.33e-97 ung2 - - L - - - Uracil-DNA glycosylase
MKNOAAOH_00107 3.61e-43 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
MKNOAAOH_00108 0.0 cas9 - - L ko:K09952 - ko00000,ko01000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
MKNOAAOH_00109 4.45e-136 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MKNOAAOH_00110 7.44e-51 cas2 - - L ko:K09951 - ko00000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MKNOAAOH_00111 3e-38 - - - S - - - CRISPR-associated protein (Cas_Csn2)
MKNOAAOH_00112 1.77e-50 XK27_06915 - - K ko:K10947 - ko00000,ko03000 transcriptional regulator PadR family
MKNOAAOH_00113 2.01e-27 - - - S - - - Protein of unknown function (DUF1700)
MKNOAAOH_00114 5.5e-08 - - - S - - - Putative adhesin
MKNOAAOH_00115 8.46e-23 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
MKNOAAOH_00118 2.91e-296 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MKNOAAOH_00119 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 C-terminal domain of alpha-glycerophosphate oxidase
MKNOAAOH_00120 2.31e-130 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
MKNOAAOH_00121 1.28e-211 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MKNOAAOH_00122 3.85e-153 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MKNOAAOH_00123 3.11e-133 potC - - U ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MKNOAAOH_00124 1.19e-201 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MKNOAAOH_00125 7.9e-169 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
MKNOAAOH_00126 9.74e-147 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
MKNOAAOH_00127 5.74e-138 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MKNOAAOH_00128 3.36e-85 yciB - - M - - - ErfK YbiS YcfS YnhG
MKNOAAOH_00129 2.68e-69 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MKNOAAOH_00130 2.49e-285 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MKNOAAOH_00131 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MKNOAAOH_00132 2.22e-131 pgm3 - - G - - - phosphoglycerate mutase
MKNOAAOH_00133 2.05e-70 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
MKNOAAOH_00134 6.33e-62 - - - C - - - Flavodoxin
MKNOAAOH_00135 5.24e-79 yphH - - S - - - Cupin domain
MKNOAAOH_00136 1.78e-60 yphJ 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 decarboxylase
MKNOAAOH_00137 5.89e-177 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
MKNOAAOH_00138 4.23e-135 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
MKNOAAOH_00139 1.32e-188 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MKNOAAOH_00140 3.17e-120 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MKNOAAOH_00141 2.63e-167 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
MKNOAAOH_00142 2.84e-107 - - - C - - - nitroreductase
MKNOAAOH_00143 5.05e-105 adc 4.1.1.4 - Q ko:K01574 ko00072,ko00640,ko01100,map00072,map00640,map01100 ko00000,ko00001,ko00002,ko01000 Acetoacetate decarboxylase (ADC)
MKNOAAOH_00144 1.16e-136 - 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 3-hydroxyacyl-CoA dehydrogenase
MKNOAAOH_00145 1.5e-214 npr 1.11.1.1 - S ko:K05910 - ko00000,ko01000 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
MKNOAAOH_00146 0.0 speA 4.1.1.17, 4.1.1.18, 4.1.1.19 - E ko:K01581,ko:K01582,ko:K01585 ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Orn/Lys/Arg decarboxylase, C-terminal domain
MKNOAAOH_00148 1.78e-191 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MKNOAAOH_00149 1.02e-73 metI - - U ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MKNOAAOH_00150 3.63e-163 metQ - - M ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
MKNOAAOH_00151 5.64e-68 - - - S - - - Protein of unknown function (DUF4256)
MKNOAAOH_00154 1.49e-223 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
MKNOAAOH_00155 7.47e-213 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Transketolase, C-terminal domain protein
MKNOAAOH_00156 2.72e-230 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MKNOAAOH_00157 4.36e-291 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
MKNOAAOH_00158 2.72e-186 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
MKNOAAOH_00159 2.36e-72 - - - S - - - Protein of unknown function (DUF975)
MKNOAAOH_00160 4.91e-79 - - - E - - - GDSL-like Lipase/Acylhydrolase family
MKNOAAOH_00161 1.01e-16 - - - - - - - -
MKNOAAOH_00162 3.81e-37 XK27_08630 - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
MKNOAAOH_00163 2.79e-281 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
MKNOAAOH_00164 1.39e-111 fruR - - K ko:K03436 - ko00000,ko03000 DeoR C terminal sensor domain
MKNOAAOH_00165 4.7e-192 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
MKNOAAOH_00166 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase System
MKNOAAOH_00167 1.62e-176 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Peptidase dimerisation domain
MKNOAAOH_00168 3.11e-188 - - - E - - - glutamate:sodium symporter activity
MKNOAAOH_00169 3.01e-183 - - - Q - - - Imidazolonepropionase and related amidohydrolases
MKNOAAOH_00170 1.66e-57 cps3F - - - - - - -
MKNOAAOH_00171 3.66e-107 - - - S - - - Membrane
MKNOAAOH_00172 0.0 - - - E - - - Amino acid permease
MKNOAAOH_00173 2.03e-50 cadA - - P - - - P-type ATPase
MKNOAAOH_00174 1.88e-211 cadA - - P - - - P-type ATPase
MKNOAAOH_00175 2.47e-146 degV - - S - - - EDD domain protein, DegV family
MKNOAAOH_00176 2.05e-189 yfdH - GT2 M ko:K12999 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
MKNOAAOH_00177 1.18e-69 - - - F - - - glutamine amidotransferase
MKNOAAOH_00178 1.86e-35 yuxO - - Q - - - Thioesterase superfamily
MKNOAAOH_00179 6.07e-186 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MKNOAAOH_00180 1.7e-175 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
MKNOAAOH_00181 1.18e-103 - - - S - - - L,D-transpeptidase catalytic domain
MKNOAAOH_00182 1.44e-208 - - - EGP ko:K18934 - ko00000,ko02000 Major Facilitator Superfamily
MKNOAAOH_00183 5.68e-21 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
MKNOAAOH_00184 2.98e-284 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
MKNOAAOH_00185 9.74e-159 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
MKNOAAOH_00186 1.39e-42 - - - S - - - Protein of unknown function (DUF1634)
MKNOAAOH_00187 3.16e-153 - - - S ko:K07090 - ko00000 membrane transporter protein
MKNOAAOH_00188 1.02e-105 lysR5 - - K - - - LysR substrate binding domain
MKNOAAOH_00189 3.04e-71 lssY 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 phosphatidate phosphatase activity
MKNOAAOH_00190 2.9e-14 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MKNOAAOH_00191 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
MKNOAAOH_00192 3.19e-86 budA 4.1.1.5 - Q ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
MKNOAAOH_00193 2.64e-308 lysP - - E ko:K03293,ko:K11733 - ko00000,ko02000 amino acid
MKNOAAOH_00194 1.6e-262 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MKNOAAOH_00197 5.34e-31 - - - - - - - -
MKNOAAOH_00207 1.38e-165 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
MKNOAAOH_00208 5.35e-235 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MKNOAAOH_00209 2.75e-199 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
MKNOAAOH_00210 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
MKNOAAOH_00211 2.47e-151 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MKNOAAOH_00213 6.91e-73 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
MKNOAAOH_00214 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MKNOAAOH_00215 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MKNOAAOH_00216 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MKNOAAOH_00217 2.43e-28 comC 3.4.23.43 - NOU ko:K02236 - ko00000,ko00002,ko01000,ko02044 Bacterial Peptidase A24 N-terminal domain
MKNOAAOH_00218 2.95e-92 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MKNOAAOH_00219 1.39e-106 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MKNOAAOH_00220 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MKNOAAOH_00221 3.83e-116 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
MKNOAAOH_00222 1.11e-105 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
MKNOAAOH_00223 9.91e-145 vanR - - K - - - response regulator
MKNOAAOH_00224 5.29e-191 hpk31 - - T - - - Histidine kinase
MKNOAAOH_00225 5.88e-113 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
MKNOAAOH_00226 1.78e-26 - - - G - - - Transporter, major facilitator family protein
MKNOAAOH_00227 1.18e-149 - - - G - - - Transporter, major facilitator family protein
MKNOAAOH_00229 4.25e-58 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
MKNOAAOH_00230 1.43e-141 - - - L ko:K07484 - ko00000 Transposase IS66 family
MKNOAAOH_00231 5.08e-275 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MKNOAAOH_00232 0.0 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MKNOAAOH_00233 4.44e-44 - - - K - - - Bacterial regulatory proteins, tetR family
MKNOAAOH_00234 1.24e-45 ycfI - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
MKNOAAOH_00235 3.61e-213 ycfI - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
MKNOAAOH_00236 1.36e-316 yfiC - - V ko:K06147 - ko00000,ko02000 ABC transporter
MKNOAAOH_00237 1.29e-11 - - - - - - - -
MKNOAAOH_00238 6.14e-58 yyaT - - K ko:K02348 - ko00000 protein acetylation
MKNOAAOH_00239 1.2e-67 ymdB - - L - - - phosphatase homologous to the C-terminal domain of histone macroH2A1
MKNOAAOH_00240 3.17e-94 lemA - - S ko:K03744 - ko00000 LemA family
MKNOAAOH_00241 1.77e-155 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
MKNOAAOH_00243 1.15e-170 - - - L - - - DNA helicase
MKNOAAOH_00244 6.54e-235 - - - L - - - Probable transposase
MKNOAAOH_00245 2.17e-151 - - - L - - - DNA helicase
MKNOAAOH_00246 1.94e-160 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MKNOAAOH_00247 2.82e-217 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
MKNOAAOH_00248 2.78e-129 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
MKNOAAOH_00249 1.58e-105 ybhF_2 - - V ko:K01990 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
MKNOAAOH_00250 5.19e-130 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
MKNOAAOH_00251 2.7e-40 - - - K - - - Bacterial regulatory proteins, tetR family
MKNOAAOH_00252 1.49e-54 - - - ET - - - Bacterial extracellular solute-binding proteins, family 3
MKNOAAOH_00253 2.66e-191 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
MKNOAAOH_00254 6.48e-162 - - - - - - - -
MKNOAAOH_00255 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MKNOAAOH_00256 3.62e-133 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
MKNOAAOH_00257 5.68e-111 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MKNOAAOH_00258 3.25e-170 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MKNOAAOH_00259 1.9e-31 veg - - S - - - Biofilm formation stimulator VEG
MKNOAAOH_00260 7.69e-115 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
MKNOAAOH_00261 1.36e-171 arcT - - E - - - Cys/Met metabolism PLP-dependent enzyme
MKNOAAOH_00262 5.91e-61 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
MKNOAAOH_00263 5.09e-148 ispE 2.7.1.148 - F ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MKNOAAOH_00264 1.05e-193 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
MKNOAAOH_00266 1.49e-113 sip - - L - - - Belongs to the 'phage' integrase family
MKNOAAOH_00267 9.88e-106 - - - S - - - Domain of unknown function DUF1829
MKNOAAOH_00268 1.44e-20 - - - - - - - -
MKNOAAOH_00269 1.31e-85 - - - T - - - PemK-like, MazF-like toxin of type II toxin-antitoxin system
MKNOAAOH_00270 1.89e-14 - - - - - - - -
MKNOAAOH_00273 1.41e-48 - - - K - - - Peptidase S24-like
MKNOAAOH_00276 1.03e-19 - - - K - - - Cro/C1-type HTH DNA-binding domain
MKNOAAOH_00279 2.06e-19 - - - K - - - Helix-turn-helix XRE-family like proteins
MKNOAAOH_00280 2.13e-52 - - - S - - - DNA binding
MKNOAAOH_00287 6.26e-66 - - - S - - - Putative HNHc nuclease
MKNOAAOH_00288 3.78e-32 - - - L - - - N-terminal phage replisome organiser (Phage_rep_org_N)
MKNOAAOH_00291 5.3e-28 - - - - - - - -
MKNOAAOH_00292 4.93e-83 - - - - - - - -
MKNOAAOH_00301 6.36e-43 - - - S - - - Phage transcriptional regulator, ArpU family
MKNOAAOH_00302 3.64e-70 - - - V - - - Abi-like protein
MKNOAAOH_00304 6.4e-105 - - - L - - - HNH nucleases
MKNOAAOH_00305 1.05e-107 - - - L - - - Phage terminase, small subunit
MKNOAAOH_00306 0.0 - - - S - - - Phage Terminase
MKNOAAOH_00308 1.31e-250 - - - S - - - Phage portal protein
MKNOAAOH_00309 1.99e-146 - 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S14 family
MKNOAAOH_00310 4.1e-245 - - - S - - - Phage capsid family
MKNOAAOH_00311 2.52e-28 - - - S - - - Phage gp6-like head-tail connector protein
MKNOAAOH_00312 1.33e-70 - - - S - - - Phage head-tail joining protein
MKNOAAOH_00313 3.72e-67 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
MKNOAAOH_00314 6.94e-74 - - - S - - - Protein of unknown function (DUF806)
MKNOAAOH_00315 4.34e-99 - - - S - - - Phage tail tube protein
MKNOAAOH_00316 4.76e-25 - - - S - - - Phage tail assembly chaperone proteins, TAC
MKNOAAOH_00318 0.0 - - - L - - - Phage tail tape measure protein TP901
MKNOAAOH_00319 1.88e-101 - - - S - - - Phage tail protein
MKNOAAOH_00320 5.31e-151 rny - - D ko:K12088,ko:K18682 ko03018,ko05120,map03018,map05120 ko00000,ko00001,ko00002,ko01000,ko02044,ko03019 peptidase
MKNOAAOH_00322 1.34e-39 - - - S - - - Calcineurin-like phosphoesterase
MKNOAAOH_00329 2.63e-29 - - - S - - - Bacteriophage holin of superfamily 6 (Holin_LLH)
MKNOAAOH_00330 3.23e-123 - - - M - - - hydrolase, family 25
MKNOAAOH_00331 1.93e-253 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
MKNOAAOH_00332 1.6e-248 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
MKNOAAOH_00333 3.5e-190 araT 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
MKNOAAOH_00334 4.48e-158 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MKNOAAOH_00335 9.41e-142 pfoSR - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
MKNOAAOH_00336 6.82e-235 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MKNOAAOH_00337 1.26e-68 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
MKNOAAOH_00338 7.37e-175 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
MKNOAAOH_00339 4.84e-72 - - - EGP - - - Transmembrane secretion effector
MKNOAAOH_00340 7.9e-257 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MKNOAAOH_00341 2.25e-216 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MKNOAAOH_00342 1.76e-24 rimL 1.1.1.25 - J ko:K00014,ko:K03817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko03009 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MKNOAAOH_00343 1.94e-139 dkgB - - S - - - Aldo/keto reductase family
MKNOAAOH_00344 2.13e-32 - - - - - - - -
MKNOAAOH_00345 9.74e-100 - - - F - - - Phosphorylase superfamily
MKNOAAOH_00346 0.0 ykpA - - S - - - ABC transporter, ATP-binding protein
MKNOAAOH_00347 1.4e-43 ytkL - - S - - - Beta-lactamase superfamily domain
MKNOAAOH_00349 4.25e-58 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
MKNOAAOH_00350 1.43e-141 - - - L ko:K07484 - ko00000 Transposase IS66 family
MKNOAAOH_00351 2.55e-26 ytkL - - S - - - Belongs to the UPF0173 family
MKNOAAOH_00352 4.69e-122 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MKNOAAOH_00353 1.59e-156 yibE - - S - - - overlaps another CDS with the same product name
MKNOAAOH_00354 6.71e-110 - - - S - - - overlaps another CDS with the same product name
MKNOAAOH_00356 1.68e-61 spoVK - - O - - - ATPase family associated with various cellular activities (AAA)
MKNOAAOH_00358 8.25e-26 recD2_2 3.1.11.5 - L ko:K01144 - ko00000,ko01000 PIF1-like helicase
MKNOAAOH_00360 7.3e-79 - - - - - - - -
MKNOAAOH_00361 3.72e-133 - - - S ko:K09936 ko02024,map02024 ko00000,ko00001,ko02000 Putative inner membrane exporter, YdcZ
MKNOAAOH_00362 2.88e-110 - - - S - - - hydrolase
MKNOAAOH_00363 6.95e-261 ywfO - - S ko:K06885 - ko00000 HD domain protein
MKNOAAOH_00364 4.97e-110 - - - F - - - glutamine amidotransferase
MKNOAAOH_00365 1.8e-32 ywiB - - S - - - Domain of unknown function (DUF1934)
MKNOAAOH_00366 1.75e-57 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MKNOAAOH_00367 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MKNOAAOH_00369 4.42e-253 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MKNOAAOH_00370 1.93e-240 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MKNOAAOH_00371 5.02e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
MKNOAAOH_00372 1.29e-78 - - - - - - - -
MKNOAAOH_00373 0.0 uvrB3 3.1.12.1 - KL ko:K07464 - ko00000,ko01000,ko02048 DEAD_2
MKNOAAOH_00375 3.5e-99 - - - S - - - Cell surface protein
MKNOAAOH_00377 2.89e-229 pbuG - - S ko:K06901 - ko00000,ko02000 permease
MKNOAAOH_00378 2.54e-105 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
MKNOAAOH_00380 7.55e-78 yciB - - M - - - ErfK YbiS YcfS YnhG
MKNOAAOH_00381 2.99e-81 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2263)
MKNOAAOH_00382 2.32e-224 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MKNOAAOH_00383 1.32e-282 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MKNOAAOH_00384 1.5e-40 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MKNOAAOH_00385 7.6e-182 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MKNOAAOH_00387 5e-64 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
MKNOAAOH_00388 9.14e-117 yunF - - F - - - Protein of unknown function DUF72
MKNOAAOH_00389 4.01e-197 yngD - - S ko:K07097 - ko00000 DHHA1 domain
MKNOAAOH_00390 3.12e-57 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
MKNOAAOH_00391 2.05e-75 - - - - - - - -
MKNOAAOH_00392 2.05e-53 ytlR - - I - - - Diacylglycerol kinase catalytic domain
MKNOAAOH_00393 3.84e-31 - - - S - - - Cytochrome B5
MKNOAAOH_00395 2.25e-79 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
MKNOAAOH_00396 1.81e-241 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MKNOAAOH_00397 9.74e-126 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
MKNOAAOH_00398 8.16e-135 yueF - - S - - - AI-2E family transporter
MKNOAAOH_00399 3.8e-201 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
MKNOAAOH_00400 1.97e-146 tagH 3.6.3.40 - GM ko:K01990,ko:K09691,ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
MKNOAAOH_00401 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MKNOAAOH_00402 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 -beta-galactosidase
MKNOAAOH_00403 0.0 lacP - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
MKNOAAOH_00404 3.21e-139 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
MKNOAAOH_00405 8.74e-225 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MKNOAAOH_00406 1.26e-207 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
MKNOAAOH_00407 4.92e-252 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
MKNOAAOH_00408 0.0 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
MKNOAAOH_00409 6.64e-131 - - - G - - - MucBP domain
MKNOAAOH_00410 1.24e-31 XK27_09445 - - S - - - Domain of unknown function (DUF1827)
MKNOAAOH_00411 0.0 clpE - - O ko:K03697 - ko00000,ko03110 Belongs to the ClpA ClpB family
MKNOAAOH_00412 1.5e-22 - - - - - - - -
MKNOAAOH_00413 5.69e-49 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
MKNOAAOH_00414 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MKNOAAOH_00415 2.56e-203 pimB 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
MKNOAAOH_00416 1.84e-163 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
MKNOAAOH_00417 1.45e-164 mprF - - I ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MKNOAAOH_00418 3.45e-36 ykuJ - - S - - - Protein of unknown function (DUF1797)
MKNOAAOH_00419 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MKNOAAOH_00422 5.34e-31 - - - - - - - -
MKNOAAOH_00435 3.58e-273 pckA 4.1.1.49 - H ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Phosphoenolpyruvate carboxykinase
MKNOAAOH_00436 1.53e-61 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
MKNOAAOH_00437 1.87e-85 coiA - - S ko:K06198 - ko00000 Competence protein
MKNOAAOH_00438 3.54e-288 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
MKNOAAOH_00439 1.01e-53 yjbH - - Q - - - Thioredoxin
MKNOAAOH_00440 1.76e-124 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
MKNOAAOH_00441 2.58e-150 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
MKNOAAOH_00442 6.71e-155 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
MKNOAAOH_00443 7.48e-147 pstB2 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MKNOAAOH_00444 5.27e-148 pstB1 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MKNOAAOH_00445 6.44e-73 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
MKNOAAOH_00446 1.21e-188 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
MKNOAAOH_00447 3.97e-100 - - - S - - - VIT family
MKNOAAOH_00448 2.71e-107 - - - S - - - membrane
MKNOAAOH_00449 1.97e-53 - - - K - - - Domain of unknown function (DUF1836)
MKNOAAOH_00450 8.68e-83 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
MKNOAAOH_00451 3.39e-47 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
MKNOAAOH_00452 3.43e-96 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MKNOAAOH_00454 6.19e-10 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MKNOAAOH_00456 3.73e-218 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
MKNOAAOH_00457 1.26e-202 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
MKNOAAOH_00458 4.81e-54 - - - S - - - VanZ like family
MKNOAAOH_00459 4e-153 yebC - - K - - - Transcriptional regulatory protein
MKNOAAOH_00460 4.05e-130 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MKNOAAOH_00461 5.53e-153 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
MKNOAAOH_00462 7.88e-122 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
MKNOAAOH_00463 4.34e-36 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 competence protein ComGC
MKNOAAOH_00464 7.13e-18 - - - - ko:K02246 - ko00000,ko00002,ko02044 -
MKNOAAOH_00468 1.41e-123 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
MKNOAAOH_00469 3.13e-239 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
MKNOAAOH_00470 9.2e-73 - - - S - - - Calcineurin-like phosphoesterase
MKNOAAOH_00471 4.29e-77 yutD - - S - - - Protein of unknown function (DUF1027)
MKNOAAOH_00472 1.19e-145 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MKNOAAOH_00473 4.54e-38 - - - S - - - Protein of unknown function (DUF1461)
MKNOAAOH_00474 3.79e-118 dedA - - S ko:K03975 - ko00000 SNARE associated Golgi protein
MKNOAAOH_00475 1.63e-118 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
MKNOAAOH_00476 2.55e-65 yugI - - J ko:K07570 - ko00000 general stress protein
MKNOAAOH_00477 5.34e-31 - - - - - - - -
MKNOAAOH_00497 5.21e-226 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MKNOAAOH_00498 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
MKNOAAOH_00499 4.35e-247 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
MKNOAAOH_00500 4e-243 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
MKNOAAOH_00501 1.01e-77 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
MKNOAAOH_00502 3.13e-104 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MKNOAAOH_00503 2.17e-242 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
MKNOAAOH_00504 5.57e-225 - - - S - - - Protein of unknown function DUF262
MKNOAAOH_00506 5.97e-49 - - - - - - - -
MKNOAAOH_00507 7.61e-86 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MKNOAAOH_00508 1.29e-79 - - - K - - - Transcriptional regulator, MarR family
MKNOAAOH_00509 3e-129 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MKNOAAOH_00510 1.48e-36 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
MKNOAAOH_00511 2.98e-131 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
MKNOAAOH_00512 1.09e-125 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
MKNOAAOH_00513 5.79e-247 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MKNOAAOH_00514 2.34e-60 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MKNOAAOH_00515 5.39e-83 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MKNOAAOH_00516 2.06e-274 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
MKNOAAOH_00517 3.3e-160 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MKNOAAOH_00518 4.27e-130 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 alpha subunit
MKNOAAOH_00519 7.35e-140 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
MKNOAAOH_00520 3.82e-291 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MKNOAAOH_00521 2.45e-304 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
MKNOAAOH_00522 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MKNOAAOH_00523 1.05e-152 gla - - U ko:K02440 - ko00000,ko02000 Major intrinsic protein
MKNOAAOH_00524 3.09e-59 ykuL - - S - - - CBS domain
MKNOAAOH_00525 1.39e-91 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MKNOAAOH_00526 5.76e-224 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MKNOAAOH_00527 2.42e-117 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
MKNOAAOH_00529 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
MKNOAAOH_00530 2.92e-28 yheA - - S - - - Belongs to the UPF0342 family
MKNOAAOH_00531 6.56e-163 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 Metal dependent phosphohydrolases with conserved 'HD' motif.
MKNOAAOH_00532 1.22e-144 prsA 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MKNOAAOH_00534 3.15e-69 hit - - FG ko:K02503 - ko00000,ko04147 histidine triad
MKNOAAOH_00535 4.7e-121 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MKNOAAOH_00536 3.98e-88 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
MKNOAAOH_00537 3.39e-125 ytmP - - M - - - Choline/ethanolamine kinase
MKNOAAOH_00538 8.2e-131 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MKNOAAOH_00539 2.95e-59 ytpP - - CO - - - Thioredoxin
MKNOAAOH_00540 1.43e-96 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MKNOAAOH_00541 2.9e-297 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
MKNOAAOH_00542 1.24e-282 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
MKNOAAOH_00543 6.4e-80 phaJ - - I - - - N-terminal half of MaoC dehydratase
MKNOAAOH_00544 3.7e-87 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
MKNOAAOH_00545 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MKNOAAOH_00546 5.99e-137 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MKNOAAOH_00547 2.15e-62 coaE 2.7.1.24 - H ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MKNOAAOH_00548 1.04e-85 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MKNOAAOH_00549 2.46e-95 dnaB - - L ko:K03346 - ko00000,ko03032 replication initiation and membrane attachment
MKNOAAOH_00550 1.15e-136 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
MKNOAAOH_00551 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MKNOAAOH_00552 1.25e-102 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MKNOAAOH_00553 4.44e-34 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
MKNOAAOH_00554 5.01e-69 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MKNOAAOH_00555 3.33e-91 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
MKNOAAOH_00556 2.94e-229 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
MKNOAAOH_00557 1.36e-40 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein
MKNOAAOH_00558 1e-98 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MKNOAAOH_00559 1.4e-90 yqeK - - H - - - Hydrolase, HD family
MKNOAAOH_00560 2.79e-65 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MKNOAAOH_00561 2.64e-103 - - - H - - - Nodulation protein S (NodS)
MKNOAAOH_00562 3.25e-153 ylbM - - S - - - Belongs to the UPF0348 family
MKNOAAOH_00563 1.58e-73 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
MKNOAAOH_00564 8.93e-35 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
MKNOAAOH_00565 9.97e-114 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
MKNOAAOH_00566 9.79e-120 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
MKNOAAOH_00567 6.9e-37 yazA - - L ko:K07461 - ko00000 GIY-YIG catalytic domain protein
MKNOAAOH_00568 4.91e-172 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
MKNOAAOH_00569 7.31e-164 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MKNOAAOH_00570 1.18e-98 - - - L - - - Belongs to the 'phage' integrase family
MKNOAAOH_00571 1.72e-37 - - - - - - - -
MKNOAAOH_00572 8.35e-37 - - - S - - - Domain of unknown function (DUF4352)
MKNOAAOH_00573 1.36e-48 - - - E - - - IrrE N-terminal-like domain
MKNOAAOH_00574 4.46e-56 - - - K ko:K07727 - ko00000,ko03000 addiction module antidote protein HigA
MKNOAAOH_00575 4.52e-17 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
MKNOAAOH_00579 4.99e-65 - - - S - - - Hypothetical protein (DUF2513)
MKNOAAOH_00580 6.72e-27 - - - - - - - -
MKNOAAOH_00585 1.88e-203 - - - D - - - AAA domain
MKNOAAOH_00586 2.34e-132 - - - S - - - AAA domain
MKNOAAOH_00587 4.67e-67 - - - - - - - -
MKNOAAOH_00588 1.89e-51 - - - - - - - -
MKNOAAOH_00589 1.5e-104 - - - - - - - -
MKNOAAOH_00590 0.0 - - - L - - - Helicase C-terminal domain protein
MKNOAAOH_00591 0.0 - - - L - - - Primase C terminal 2 (PriCT-2)
MKNOAAOH_00592 1.87e-57 - - - S - - - magnesium ion binding
MKNOAAOH_00602 1.53e-27 - - - - - - - -
MKNOAAOH_00603 6.43e-208 - - - S ko:K06909 - ko00000 Terminase RNAseH like domain
MKNOAAOH_00604 2.18e-176 - - - S - - - Phage portal protein, SPP1 Gp6-like
MKNOAAOH_00605 1.57e-116 - - - S - - - Phage minor capsid protein 2
MKNOAAOH_00606 7.3e-29 - - - S - - - Phage minor structural protein GP20
MKNOAAOH_00607 4.34e-125 - - - S - - - T=7 icosahedral viral capsid
MKNOAAOH_00609 1.86e-39 - - - S - - - Minor capsid protein
MKNOAAOH_00612 1.35e-49 - - - N - - - domain, Protein
MKNOAAOH_00614 1.44e-47 - - - S - - - Bacteriophage Gp15 protein
MKNOAAOH_00615 1.27e-111 - - - L - - - Phage tail tape measure protein TP901
MKNOAAOH_00617 5.5e-118 - - - M - - - Prophage endopeptidase tail
MKNOAAOH_00619 2.73e-89 - - - S - - - Domain of unknown function (DUF2479)
MKNOAAOH_00624 7.02e-27 - - - S - - - Bacteriophage holin of superfamily 6 (Holin_LLH)
MKNOAAOH_00625 1.15e-141 - - - S - - - N-acetylmuramoyl-L-alanine amidase activity
MKNOAAOH_00626 1.82e-49 - - - - - - - -
MKNOAAOH_00627 4.68e-119 dgk1 2.7.1.76 - F ko:K10353 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 deoxynucleoside kinase
MKNOAAOH_00628 1.89e-75 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MKNOAAOH_00629 1.28e-199 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MKNOAAOH_00630 3.59e-285 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MKNOAAOH_00631 3.82e-136 - 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MKNOAAOH_00633 1.46e-141 csrR - - K - - - response regulator
MKNOAAOH_00634 2.03e-218 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MKNOAAOH_00635 1.19e-151 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MKNOAAOH_00636 1.6e-24 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
MKNOAAOH_00637 3.54e-172 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
MKNOAAOH_00638 4.27e-143 - - - - - - - -
MKNOAAOH_00639 1.61e-147 - - - - - - - -
MKNOAAOH_00640 1.45e-48 - - - S - - - Protein conserved in bacteria
MKNOAAOH_00641 3.77e-123 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MKNOAAOH_00642 1.4e-60 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
MKNOAAOH_00643 1.77e-47 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MKNOAAOH_00644 1.91e-132 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MKNOAAOH_00645 3.49e-183 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MKNOAAOH_00646 1.44e-23 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MKNOAAOH_00647 2.19e-104 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
MKNOAAOH_00648 6.31e-154 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
MKNOAAOH_00649 5.91e-65 argR2 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
MKNOAAOH_00650 1.05e-235 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
MKNOAAOH_00651 1.29e-106 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MKNOAAOH_00652 7.41e-41 ynzC - - S - - - UPF0291 protein
MKNOAAOH_00653 3.98e-36 yneF - - S ko:K09976 - ko00000 UPF0154 protein
MKNOAAOH_00654 2.28e-118 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
MKNOAAOH_00655 2.16e-58 - - - S - - - mazG nucleotide pyrophosphohydrolase
MKNOAAOH_00656 2.95e-86 yciQ - - P - - - membrane protein (DUF2207)
MKNOAAOH_00658 7.58e-30 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
MKNOAAOH_00659 2.55e-49 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MKNOAAOH_00660 1.11e-90 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Peptidase, S54 family
MKNOAAOH_00661 2.47e-34 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
MKNOAAOH_00662 8.22e-203 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
MKNOAAOH_00663 2.92e-60 yqhL - - P - - - Rhodanese-like protein
MKNOAAOH_00664 6.17e-24 WQ51_02665 - - S - - - Protein of unknown function (DUF3042)
MKNOAAOH_00665 6.09e-141 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MKNOAAOH_00666 1.56e-257 ynbB - - P - - - aluminum resistance
MKNOAAOH_00667 1.3e-59 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 Transcriptional regulator
MKNOAAOH_00668 3.28e-312 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
MKNOAAOH_00670 6.13e-47 - 2.1.1.63 - H ko:K00567 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MKNOAAOH_00671 8.28e-64 manO - - S - - - Domain of unknown function (DUF956)
MKNOAAOH_00672 1.02e-147 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
MKNOAAOH_00673 8.26e-105 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MKNOAAOH_00674 2.86e-134 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MKNOAAOH_00675 1.58e-131 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
MKNOAAOH_00676 2.52e-196 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
MKNOAAOH_00677 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MKNOAAOH_00678 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MKNOAAOH_00679 1.16e-85 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
MKNOAAOH_00680 1.25e-216 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
MKNOAAOH_00681 3.32e-53 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
MKNOAAOH_00682 2.85e-35 ylxQ - - J - - - ribosomal protein
MKNOAAOH_00683 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MKNOAAOH_00684 6.33e-74 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MKNOAAOH_00685 1.16e-151 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MKNOAAOH_00686 7.4e-120 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
MKNOAAOH_00687 1.51e-165 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MKNOAAOH_00688 3.65e-75 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MKNOAAOH_00689 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
MKNOAAOH_00690 5.74e-218 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MKNOAAOH_00691 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MKNOAAOH_00693 8.61e-258 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MKNOAAOH_00694 7.44e-153 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MKNOAAOH_00695 1.83e-41 - - - - - - - -
MKNOAAOH_00696 2.05e-138 ampC - - V - - - Beta-lactamase
MKNOAAOH_00697 9.35e-141 cobQ - - S ko:K07009 - ko00000 glutamine amidotransferase
MKNOAAOH_00698 1.79e-278 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Domain of unknown function (DUF1727)
MKNOAAOH_00699 1.19e-111 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
MKNOAAOH_00700 4.22e-230 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MKNOAAOH_00701 7.51e-114 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MKNOAAOH_00702 1.9e-171 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MKNOAAOH_00703 2.18e-129 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MKNOAAOH_00704 9.47e-124 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
MKNOAAOH_00705 1.39e-27 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MKNOAAOH_00706 2.96e-57 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MKNOAAOH_00707 1.62e-73 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MKNOAAOH_00708 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MKNOAAOH_00709 3.29e-181 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MKNOAAOH_00710 8.04e-313 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MKNOAAOH_00711 3.59e-69 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
MKNOAAOH_00712 8.32e-21 ywzB - - S - - - Protein of unknown function (DUF1146)
MKNOAAOH_00713 2.53e-261 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MKNOAAOH_00714 2.82e-214 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
MKNOAAOH_00715 3.25e-36 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
MKNOAAOH_00716 2.21e-19 - - - S - - - Protein of unknown function (DUF2969)
MKNOAAOH_00717 2.21e-236 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
MKNOAAOH_00718 9.86e-36 spxA 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
MKNOAAOH_00719 5.39e-120 - - - M - - - Phosphotransferase enzyme family
MKNOAAOH_00720 8.34e-132 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
MKNOAAOH_00721 8.22e-30 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MKNOAAOH_00722 1.87e-153 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MKNOAAOH_00723 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MKNOAAOH_00724 1.55e-177 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MKNOAAOH_00725 7.17e-192 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MKNOAAOH_00726 3.18e-115 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
MKNOAAOH_00727 1.98e-238 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
MKNOAAOH_00728 1.38e-145 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MKNOAAOH_00729 4.31e-73 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
MKNOAAOH_00730 1.33e-35 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
MKNOAAOH_00731 7.35e-69 yloU - - S - - - Asp23 family, cell envelope-related function
MKNOAAOH_00732 4.03e-301 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
MKNOAAOH_00733 1.56e-305 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MKNOAAOH_00734 1.08e-180 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MKNOAAOH_00735 9.72e-35 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
MKNOAAOH_00736 4.17e-129 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MKNOAAOH_00737 1.04e-290 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
MKNOAAOH_00738 1.12e-187 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MKNOAAOH_00739 1.51e-53 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MKNOAAOH_00740 9.04e-263 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MKNOAAOH_00741 1.32e-55 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
MKNOAAOH_00742 1.99e-37 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
MKNOAAOH_00743 3.22e-74 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MKNOAAOH_00744 2.25e-144 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
MKNOAAOH_00745 4.4e-78 pat 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
MKNOAAOH_00746 1.68e-248 - - - E ko:K03294 - ko00000 amino acid
MKNOAAOH_00747 2.49e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MKNOAAOH_00748 1.33e-43 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
MKNOAAOH_00749 2.6e-53 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MKNOAAOH_00750 2.18e-146 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MKNOAAOH_00751 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MKNOAAOH_00752 0.000361 - - - S - - - Tetratricopeptide repeat
MKNOAAOH_00753 9.71e-274 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MKNOAAOH_00754 6.79e-246 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MKNOAAOH_00755 5.22e-251 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MKNOAAOH_00756 1.93e-315 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MKNOAAOH_00757 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MKNOAAOH_00758 1.47e-30 ykzG - - S - - - Belongs to the UPF0356 family
MKNOAAOH_00759 1.41e-32 - - - - - - - -
MKNOAAOH_00760 1.36e-111 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MKNOAAOH_00761 9.49e-22 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the LDH MDH superfamily
MKNOAAOH_00762 3.42e-31 yktA - - S - - - Belongs to the UPF0223 family
MKNOAAOH_00763 1.22e-95 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the inositol monophosphatase superfamily
MKNOAAOH_00764 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
MKNOAAOH_00765 2.2e-187 manL 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
MKNOAAOH_00766 7.81e-147 manY - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system
MKNOAAOH_00767 2.92e-189 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
MKNOAAOH_00768 4.04e-126 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
MKNOAAOH_00769 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MKNOAAOH_00770 2.86e-24 ylbG - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
MKNOAAOH_00771 2.14e-95 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
MKNOAAOH_00772 3.76e-65 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MKNOAAOH_00773 5.17e-167 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
MKNOAAOH_00774 6.07e-123 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
MKNOAAOH_00775 9.14e-41 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MKNOAAOH_00776 4.77e-132 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MKNOAAOH_00777 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MKNOAAOH_00778 1.24e-282 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MKNOAAOH_00779 1.71e-175 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
MKNOAAOH_00780 6.95e-96 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MKNOAAOH_00781 6.93e-292 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
MKNOAAOH_00782 3.96e-202 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
MKNOAAOH_00783 1.23e-118 - - - S - - - Acyltransferase family
MKNOAAOH_00784 2.77e-242 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MKNOAAOH_00785 2.58e-156 - - - K - - - LysR substrate binding domain
MKNOAAOH_00787 6.94e-28 - - - - - - - -
MKNOAAOH_00788 2.81e-74 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
MKNOAAOH_00789 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
MKNOAAOH_00790 3.64e-63 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
MKNOAAOH_00791 1.71e-90 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
MKNOAAOH_00792 4.29e-186 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
MKNOAAOH_00793 4.16e-133 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
MKNOAAOH_00794 3.76e-143 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MKNOAAOH_00795 5.67e-173 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
MKNOAAOH_00796 2.53e-156 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
MKNOAAOH_00797 6.38e-120 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 mevalonate kinase
MKNOAAOH_00798 1.01e-273 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
MKNOAAOH_00799 1.35e-46 ypmB - - S - - - Protein conserved in bacteria
MKNOAAOH_00800 2.59e-180 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
MKNOAAOH_00801 6.95e-300 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
MKNOAAOH_00802 8.09e-72 dnaD - - L ko:K02086 - ko00000 DnaD domain protein
MKNOAAOH_00803 1.26e-107 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MKNOAAOH_00804 3.63e-101 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MKNOAAOH_00805 4.35e-160 yitT - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
MKNOAAOH_00806 3.38e-116 - - - M - - - transferase activity, transferring glycosyl groups
MKNOAAOH_00807 6.04e-107 - - - M - - - Glycosyltransferase sugar-binding region containing DXD motif
MKNOAAOH_00808 1.25e-125 - - - M - - - Glycosyltransferase like family 2
MKNOAAOH_00811 2.08e-148 yqfL 2.7.11.33, 2.7.4.28 - F ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MKNOAAOH_00812 5.93e-30 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
MKNOAAOH_00813 1.87e-75 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
MKNOAAOH_00815 5.44e-87 - - - L - - - Phage integrase, N-terminal SAM-like domain
MKNOAAOH_00816 1.89e-142 ypjC - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
MKNOAAOH_00817 1.85e-136 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MKNOAAOH_00818 1.45e-167 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MKNOAAOH_00819 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 ABC transporter, ATP-binding protein
MKNOAAOH_00820 1.36e-200 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MKNOAAOH_00821 7.52e-74 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MKNOAAOH_00822 2.08e-170 - - - C - - - Aldo keto reductase
MKNOAAOH_00823 1.83e-31 - - - K - - - Transcriptional regulator
MKNOAAOH_00824 1.27e-135 ydhF - - S - - - Aldo keto reductase
MKNOAAOH_00826 3.49e-98 XK27_03630 - - E - - - GDSL-like Lipase/Acylhydrolase
MKNOAAOH_00827 7.98e-69 ypmS - - S - - - Uncharacterized protein conserved in bacteria (DUF2140)
MKNOAAOH_00828 1.77e-33 yozE - - S - - - Belongs to the UPF0346 family
MKNOAAOH_00829 2.54e-170 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MKNOAAOH_00830 1.67e-123 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MKNOAAOH_00831 1.96e-106 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
MKNOAAOH_00832 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MKNOAAOH_00833 4.32e-246 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MKNOAAOH_00834 6.67e-257 - - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system Galactitol-specific IIC component
MKNOAAOH_00835 2.75e-104 - - - K - - - Bacterial regulatory proteins, tetR family
MKNOAAOH_00836 6.46e-165 ybhF_1 - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
MKNOAAOH_00837 1.17e-97 - - - M ko:K01992 - ko00000,ko00002,ko02000 Exporter of polyketide antibiotics
MKNOAAOH_00838 4.14e-147 - - - M ko:K01992 - ko00000,ko00002,ko02000 Exporter of polyketide antibiotics
MKNOAAOH_00839 4.16e-129 pgm - - G - - - Phosphoglycerate mutase family
MKNOAAOH_00840 2.03e-48 - - - S - - - repeat protein
MKNOAAOH_00841 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MKNOAAOH_00843 7.02e-152 int3 - - L - - - Belongs to the 'phage' integrase family
MKNOAAOH_00844 8.59e-21 - - - - - - - -
MKNOAAOH_00846 3.95e-14 - - - - - - - -
MKNOAAOH_00849 8.73e-18 - - - M - - - Host cell surface-exposed lipoprotein
MKNOAAOH_00850 4.64e-05 - - - S - - - TM2 domain
MKNOAAOH_00851 1.28e-17 - - - - - - - -
MKNOAAOH_00852 1.13e-23 - - - L - - - nuclease
MKNOAAOH_00853 1.17e-10 - - - E - - - IrrE N-terminal-like domain
MKNOAAOH_00854 2.13e-33 - - - K - - - Helix-turn-helix XRE-family like proteins
MKNOAAOH_00855 3.84e-17 - - - - - - - -
MKNOAAOH_00856 2.06e-37 - - - K - - - Transcriptional regulator
MKNOAAOH_00858 1.48e-24 - - - S - - - Domain of unknown function (DUF771)
MKNOAAOH_00863 1.38e-148 - - - L - - - snf2 family
MKNOAAOH_00867 0.000746 - - - L - - - AAA domain
MKNOAAOH_00868 2.1e-146 - - - L - - - AAA domain
MKNOAAOH_00869 7.68e-46 - - - S - - - Protein of unknown function (DUF669)
MKNOAAOH_00870 1.99e-217 - - - L - - - DNA polymerase elongation subunit (Family B)
MKNOAAOH_00871 1.67e-190 - - - L ko:K06919 - ko00000 Phage plasmid primase, P4 family
MKNOAAOH_00875 1.09e-11 - - - - - - - -
MKNOAAOH_00876 3.67e-32 - - - S - - - HNH endonuclease
MKNOAAOH_00877 2.67e-70 - - - L - - - Belongs to the 'phage' integrase family
MKNOAAOH_00879 1.96e-88 - - - V - - - site-specific DNA-methyltransferase (adenine-specific) activity
MKNOAAOH_00890 7.27e-23 - - - L - - - HNH endonuclease
MKNOAAOH_00891 7.7e-42 - - - L - - - Phage terminase, small subunit
MKNOAAOH_00892 1e-262 - - - S - - - Phage Terminase
MKNOAAOH_00893 2.14e-129 - - - S - - - Phage portal protein, HK97 family
MKNOAAOH_00894 1.4e-90 - 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S14 family
MKNOAAOH_00895 1.9e-115 - - - S - - - Phage capsid family
MKNOAAOH_00896 1.48e-17 - - - L - - - Phage gp6-like head-tail connector protein
MKNOAAOH_00902 9.22e-118 - - - L - - - Phage tail tape measure protein TP901
MKNOAAOH_00903 3.42e-119 - - - S - - - Phage tail protein
MKNOAAOH_00904 0.0 rny - - D ko:K12088,ko:K18682 ko03018,ko05120,map03018,map05120 ko00000,ko00001,ko00002,ko01000,ko02044,ko03019 peptidase
MKNOAAOH_00905 1.66e-121 - - - M - - - Prophage endopeptidase tail
MKNOAAOH_00907 5.34e-34 - - - S - - - Calcineurin-like phosphoesterase
MKNOAAOH_00912 3.07e-13 - - - S - - - Bacteriophage holin
MKNOAAOH_00913 1.2e-162 - - - M - - - Glycosyl hydrolases family 25
MKNOAAOH_00914 8.63e-20 - - - - - - - -
MKNOAAOH_00917 5.71e-110 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MKNOAAOH_00918 1.95e-88 XK27_09705 - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
MKNOAAOH_00919 3.97e-56 yodB - - K - - - Transcriptional regulator, HxlR family
MKNOAAOH_00920 7.45e-220 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MKNOAAOH_00921 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MKNOAAOH_00922 1.15e-163 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MKNOAAOH_00923 4.31e-127 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
MKNOAAOH_00924 2e-88 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MKNOAAOH_00925 5.6e-17 - - - - - - - -
MKNOAAOH_00926 1.01e-182 iunH1 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 nucleoside hydrolase
MKNOAAOH_00927 5.19e-56 XK27_03960 - - S - - - Protein of unknown function (DUF3013)
MKNOAAOH_00928 3.09e-149 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
MKNOAAOH_00929 2.49e-96 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MKNOAAOH_00930 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MKNOAAOH_00931 2.53e-71 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MKNOAAOH_00932 1.27e-72 yjcF - - J - - - HAD-hyrolase-like
MKNOAAOH_00933 3.83e-56 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MKNOAAOH_00934 1.19e-164 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
MKNOAAOH_00935 2.49e-97 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MKNOAAOH_00936 7.51e-257 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
MKNOAAOH_00937 1.29e-141 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
MKNOAAOH_00938 1.82e-238 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
MKNOAAOH_00939 6.09e-109 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MKNOAAOH_00940 3.01e-114 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MKNOAAOH_00941 3.17e-173 - - - K - - - Transcriptional regulator
MKNOAAOH_00942 5.38e-185 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
MKNOAAOH_00943 4.04e-148 - - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
MKNOAAOH_00944 4.06e-218 araT1 - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
MKNOAAOH_00945 3.49e-111 murI 5.1.1.3 - M ko:K01776 ko00471,ko01100,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
MKNOAAOH_00947 3.6e-57 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MKNOAAOH_00948 9.38e-219 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
MKNOAAOH_00949 8.9e-48 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease HI
MKNOAAOH_00950 1.46e-34 - - - S - - - Family of unknown function (DUF5322)
MKNOAAOH_00951 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
MKNOAAOH_00952 8.73e-51 - - - - - - - -
MKNOAAOH_00955 8.31e-185 - - - EGP ko:K08368 - ko00000,ko02000 Sugar (and other) transporter
MKNOAAOH_00956 6.85e-98 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
MKNOAAOH_00957 3.83e-130 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MKNOAAOH_00958 1.76e-232 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
MKNOAAOH_00959 6.31e-93 - - - L - - - DNA alkylation repair enzyme
MKNOAAOH_00960 1.72e-174 - - - EG - - - EamA-like transporter family
MKNOAAOH_00961 2.75e-190 XK27_05225 - - S - - - Tetratricopeptide repeat protein
MKNOAAOH_00962 2.21e-256 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
MKNOAAOH_00963 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
MKNOAAOH_00964 1.45e-172 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
MKNOAAOH_00965 1.34e-220 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
MKNOAAOH_00966 4.92e-165 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MKNOAAOH_00967 1.21e-104 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
MKNOAAOH_00969 7.27e-119 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MKNOAAOH_00970 3.16e-199 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
MKNOAAOH_00971 5.49e-54 XK27_04120 - - S - - - Putative amino acid metabolism
MKNOAAOH_00972 5.64e-256 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MKNOAAOH_00973 0.0 clpB - - O ko:K03695 ko04213,map04213 ko00000,ko00001,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MKNOAAOH_00974 6.27e-37 clpB - - O ko:K03695 ko04213,map04213 ko00000,ko00001,ko03110 C-terminal, D2-small domain, of ClpB protein
MKNOAAOH_00975 6.47e-21 - - - S - - - Protein of unknown function (DUF2929)
MKNOAAOH_00976 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
MKNOAAOH_00977 1.7e-211 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MKNOAAOH_00978 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
MKNOAAOH_00980 7.56e-52 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
MKNOAAOH_00981 1.38e-106 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MKNOAAOH_00982 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MKNOAAOH_00983 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MKNOAAOH_00984 3.02e-245 FbpA - - K - - - Fibronectin-binding protein
MKNOAAOH_00985 2.07e-52 - - - K - - - Transcriptional regulator
MKNOAAOH_00986 4.15e-148 - - - S - - - EDD domain protein, DegV family
MKNOAAOH_00987 6.76e-92 - 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase, peptidase S26
MKNOAAOH_00988 3.4e-53 - - - S - - - ASCH
MKNOAAOH_00989 2.62e-236 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MKNOAAOH_00990 2.87e-98 - - - S - - - Calcineurin-like phosphoesterase
MKNOAAOH_00991 2.95e-121 - - - EG - - - EamA-like transporter family
MKNOAAOH_00992 4.69e-105 natB - - CP ko:K01992 - ko00000,ko00002,ko02000 ABC-type Na efflux pump, permease component
MKNOAAOH_00993 3.45e-142 natA - - S ko:K01990 - ko00000,ko00002,ko02000 Domain of unknown function (DUF4162)
MKNOAAOH_00994 2.83e-26 - - - K - - - Psort location Cytoplasmic, score
MKNOAAOH_00996 2.02e-48 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MKNOAAOH_00997 1.17e-288 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
MKNOAAOH_00998 3.19e-220 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
MKNOAAOH_00999 3.34e-76 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Low molecular weight phosphatase family
MKNOAAOH_01000 3.32e-191 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MKNOAAOH_01001 4.73e-40 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MKNOAAOH_01002 1.94e-222 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
MKNOAAOH_01003 1.25e-275 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MKNOAAOH_01005 2.72e-114 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
MKNOAAOH_01006 3.12e-197 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MKNOAAOH_01007 5.92e-40 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
MKNOAAOH_01008 2.42e-88 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MKNOAAOH_01009 2.07e-196 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
MKNOAAOH_01010 1.71e-105 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Ami_3
MKNOAAOH_01011 1.02e-111 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
MKNOAAOH_01012 1.79e-27 - - - M - - - Lysin motif
MKNOAAOH_01013 7.03e-158 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
MKNOAAOH_01014 5.38e-77 - - - S - - - Helix-turn-helix domain
MKNOAAOH_01015 6.24e-277 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
MKNOAAOH_01016 3.42e-59 - 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 6-pyruvoyl tetrahydropterin synthase
MKNOAAOH_01017 4.53e-151 icaA - - M - - - Glycosyl transferase family group 2
MKNOAAOH_01018 3.3e-52 - - - - - - - -
MKNOAAOH_01019 8.86e-109 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MKNOAAOH_01021 7.63e-237 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MKNOAAOH_01022 1.46e-262 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MKNOAAOH_01023 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
MKNOAAOH_01024 4.75e-215 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
MKNOAAOH_01025 2.03e-144 - - - EGP ko:K08166 - ko00000,ko02000 Major Facilitator Superfamily
MKNOAAOH_01026 5.29e-157 akr5f 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
MKNOAAOH_01027 4.84e-92 - - - K - - - Transcriptional regulator
MKNOAAOH_01028 1.33e-135 - - - E - - - Alpha/beta hydrolase of unknown function (DUF915)
MKNOAAOH_01029 4.82e-89 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MKNOAAOH_01030 7.89e-129 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
MKNOAAOH_01031 1.79e-120 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
MKNOAAOH_01032 2.31e-167 - - - L - - - Belongs to the 'phage' integrase family
MKNOAAOH_01033 2.77e-73 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
MKNOAAOH_01034 3.4e-259 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
MKNOAAOH_01035 0.0 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
MKNOAAOH_01037 3.91e-28 - - - F - - - Hydrolase of X-linked nucleoside diphosphate N terminal
MKNOAAOH_01038 6.25e-72 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
MKNOAAOH_01039 1.2e-87 maa 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
MKNOAAOH_01040 8.4e-94 - - - M - - - GNAT acetyltransferase
MKNOAAOH_01042 3.95e-244 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Adenine deaminase C-terminal domain
MKNOAAOH_01043 1.13e-83 ypsA - - S - - - Belongs to the UPF0398 family
MKNOAAOH_01044 6.51e-238 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
MKNOAAOH_01045 1.17e-98 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MKNOAAOH_01046 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
MKNOAAOH_01047 3.17e-143 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
MKNOAAOH_01048 3.06e-159 yitL - - S ko:K00243 - ko00000 S1 domain
MKNOAAOH_01049 7.83e-56 - - - S - - - Protein of unknown function (DUF441)
MKNOAAOH_01050 8.84e-76 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MKNOAAOH_01051 2.3e-127 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
MKNOAAOH_01052 3.83e-79 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MKNOAAOH_01053 1.58e-74 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MKNOAAOH_01054 6.85e-49 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MKNOAAOH_01055 4.25e-275 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MKNOAAOH_01056 4.03e-102 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MKNOAAOH_01057 3.63e-155 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family. XerC subfamily
MKNOAAOH_01058 1.56e-225 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
MKNOAAOH_01059 1.94e-124 ytlR - - I - - - Diacylglycerol kinase catalytic domain
MKNOAAOH_01060 2.1e-91 - - - - - - - -
MKNOAAOH_01063 1.51e-09 - - - M - - - LysM domain
MKNOAAOH_01064 4.7e-57 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
MKNOAAOH_01065 1.55e-37 ysxB - - J ko:K07584 - ko00000 Cysteine protease Prp
MKNOAAOH_01066 3.02e-64 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
MKNOAAOH_01073 3.37e-81 - - - H - - - Methyltransferase domain
MKNOAAOH_01074 1.9e-89 cps2D 5.1.3.2, 5.1.3.25 - M ko:K01784,ko:K17947 ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130 ko00000,ko00001,ko00002,ko01000 RmlD substrate binding domain
MKNOAAOH_01075 1.37e-52 - - - M - - - Acetyltransferase (GNAT) family
MKNOAAOH_01077 2.27e-29 - - - L - - - Conserved phage C-terminus (Phg_2220_C)
MKNOAAOH_01078 1.83e-50 ybbB - - S - - - Protein of unknown function (DUF1211)
MKNOAAOH_01080 2.66e-106 - 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Zinc-binding dehydrogenase
MKNOAAOH_01081 2.25e-39 - - - S - - - CHY zinc finger
MKNOAAOH_01082 7.27e-53 ywnA - - K - - - Transcriptional regulator
MKNOAAOH_01083 8.23e-105 qorB 1.6.5.2 - GM ko:K19267 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NmrA-like family
MKNOAAOH_01086 2.66e-156 - - - M - - - Glycosyl transferases group 1
MKNOAAOH_01087 4.57e-79 - - - M - - - Glycosyl transferases group 1
MKNOAAOH_01088 3.52e-225 - 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MKNOAAOH_01089 1.08e-183 - 5.1.3.6 - GM ko:K08679 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 RmlD substrate binding domain
MKNOAAOH_01090 5.3e-126 - - - S - - - Psort location CytoplasmicMembrane, score
MKNOAAOH_01091 1.36e-74 - - - M - - - Glycosyl transferases group 1
MKNOAAOH_01092 9.65e-147 - - - S - - - Glycosyltransferase WbsX
MKNOAAOH_01093 5.39e-63 - - - - - - - -
MKNOAAOH_01094 1.21e-08 - - - S - - - EpsG family
MKNOAAOH_01095 1.42e-72 - - - M - - - Glycosyltransferase like family 2
MKNOAAOH_01096 1.02e-46 - - GT2 S ko:K12990 ko02024,ko02025,map02024,map02025 ko00000,ko00001,ko01000,ko01003,ko01005 Glycosyltransferase
MKNOAAOH_01097 6.52e-89 - - - M - - - Glycosyltransferase Family 4
MKNOAAOH_01098 9.03e-97 - - - M - - - glycosyl transferase group 1
MKNOAAOH_01099 1.98e-153 - - - M - - - Glycosyl transferases group 1
MKNOAAOH_01100 7.59e-36 - - - S ko:K19429 - ko00000,ko01000 Bacterial transferase hexapeptide (six repeats)
MKNOAAOH_01101 4.04e-99 - - - M ko:K13012 - ko00000,ko01005 Bacterial sugar transferase
MKNOAAOH_01102 2.49e-209 epsN - - M ko:K19430 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
MKNOAAOH_01103 1.66e-276 capD - - M - - - Psort location CytoplasmicMembrane, score
MKNOAAOH_01104 1.41e-82 - - - D - - - AAA domain
MKNOAAOH_01105 9.81e-61 - - - M - - - Chain length determinant protein
MKNOAAOH_01106 1.44e-53 XK27_03150 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
MKNOAAOH_01107 1.69e-225 rsmF - - J - - - NOL1 NOP2 sun family protein
MKNOAAOH_01108 4.12e-82 - - - - - - - -
MKNOAAOH_01109 1.84e-104 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
MKNOAAOH_01110 5.02e-144 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
MKNOAAOH_01111 2.34e-77 yokL3 - - J - - - Acetyltransferase (GNAT) domain
MKNOAAOH_01112 5.68e-240 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MKNOAAOH_01113 5.92e-33 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
MKNOAAOH_01114 3.73e-265 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
MKNOAAOH_01116 1.19e-79 - - - K - - - helix_turn_helix, arabinose operon control protein
MKNOAAOH_01117 2.74e-69 - - - S - - - Membrane
MKNOAAOH_01118 0.0 galA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
MKNOAAOH_01119 0.0 - - - L - - - Helicase C-terminal domain protein
MKNOAAOH_01120 2.41e-65 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
MKNOAAOH_01121 6.02e-37 - - - T - - - Putative diguanylate phosphodiesterase
MKNOAAOH_01122 1.32e-152 - - - T - - - diguanylate cyclase activity
MKNOAAOH_01123 0.0 - - - S - - - Bacterial cellulose synthase subunit
MKNOAAOH_01124 1.72e-255 ydaM - - M - - - Glycosyl transferase family group 2
MKNOAAOH_01125 1.11e-198 - - - S - - - Protein conserved in bacteria
MKNOAAOH_01126 7.66e-44 - - - S - - - Protein conserved in bacteria
MKNOAAOH_01127 4.64e-238 - - - - - - - -
MKNOAAOH_01128 2.76e-163 ydaJ - - G - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
MKNOAAOH_01129 4.46e-37 - 2.7.7.65 - T ko:K02488 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko00002,ko01000,ko02022 GGDEF domain
MKNOAAOH_01131 6.07e-182 pbuO_1 - - S ko:K06901 - ko00000,ko02000 Permease family
MKNOAAOH_01132 6.22e-197 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
MKNOAAOH_01133 1.73e-134 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
MKNOAAOH_01134 4.59e-121 hepT 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
MKNOAAOH_01135 4.26e-277 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter transmembrane region
MKNOAAOH_01136 1.34e-254 cydC - - CO ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
MKNOAAOH_01137 5.29e-178 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase subunit II
MKNOAAOH_01138 1.06e-243 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
MKNOAAOH_01139 2.32e-203 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
MKNOAAOH_01140 3.05e-48 - - - M - - - LysM domain
MKNOAAOH_01141 1.38e-25 - - - P - - - Rhodanese Homology Domain
MKNOAAOH_01142 6.35e-66 - - - M - - - LysM domain protein
MKNOAAOH_01143 7.86e-116 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
MKNOAAOH_01144 4.26e-108 - - - C - - - Domain of unknown function (DUF4931)
MKNOAAOH_01146 8.05e-91 - - - O - - - ADP-ribosylglycohydrolase
MKNOAAOH_01147 4.52e-131 - - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
MKNOAAOH_01148 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MKNOAAOH_01149 1.61e-91 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
MKNOAAOH_01150 5.69e-104 ylmH - - S - - - S4 domain protein
MKNOAAOH_01151 8.19e-27 ylmG - - S ko:K02221 - ko00000,ko02044 YGGT family
MKNOAAOH_01152 8.14e-43 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MKNOAAOH_01153 1.29e-228 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MKNOAAOH_01154 6.07e-240 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MKNOAAOH_01155 6.44e-76 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MKNOAAOH_01156 1.05e-195 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MKNOAAOH_01157 2.97e-233 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MKNOAAOH_01158 3.64e-172 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MKNOAAOH_01159 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
MKNOAAOH_01160 1.05e-13 ftsL - - D - - - Essential cell division protein
MKNOAAOH_01161 3.67e-180 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MKNOAAOH_01162 5.35e-82 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
MKNOAAOH_01164 7.7e-196 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Amino acid kinase family
MKNOAAOH_01165 1.16e-05 - - - S - - - Protein of unknown function (DUF4044)
MKNOAAOH_01166 4.54e-124 ybcH - - D ko:K06889 - ko00000 Alpha beta
MKNOAAOH_01167 3.24e-138 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
MKNOAAOH_01168 2.01e-115 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MKNOAAOH_01169 3.02e-122 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
MKNOAAOH_01170 7.95e-163 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
MKNOAAOH_01171 3.56e-98 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
MKNOAAOH_01172 1.33e-70 mreD - - M ko:K03571 - ko00000,ko03036 rod shape-determining protein MreD
MKNOAAOH_01173 1.64e-121 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
MKNOAAOH_01174 2.35e-207 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
MKNOAAOH_01175 1.96e-29 - - - K ko:K03704 - ko00000,ko03000 Cold shock
MKNOAAOH_01176 3.22e-102 radC - - L ko:K03630 - ko00000 DNA repair protein
MKNOAAOH_01177 8.51e-170 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
MKNOAAOH_01178 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MKNOAAOH_01179 1.44e-248 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MKNOAAOH_01180 5.87e-204 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
MKNOAAOH_01181 2.45e-225 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MKNOAAOH_01182 6.33e-73 yebR 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
MKNOAAOH_01183 5.9e-130 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MKNOAAOH_01184 4.14e-31 XK27_05190 - - S - - - Protein of unknown function (DUF1694)
MKNOAAOH_01185 7.05e-242 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
MKNOAAOH_01187 6.08e-95 uspA - - T - - - universal stress protein
MKNOAAOH_01188 1.19e-69 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
MKNOAAOH_01189 5.17e-253 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
MKNOAAOH_01190 5.94e-158 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
MKNOAAOH_01192 1.04e-142 - - - L - - - Belongs to the 'phage' integrase family
MKNOAAOH_01194 9.86e-37 - - - K - - - Helix-turn-helix XRE-family like proteins
MKNOAAOH_01196 4.11e-16 ansR1 - - K - - - Transcriptional
MKNOAAOH_01204 9.86e-24 - - - S - - - Bifunctional DNA primase/polymerase, N-terminal
MKNOAAOH_01205 1.17e-91 - - - S ko:K06919 - ko00000 DNA primase
MKNOAAOH_01207 5.95e-96 yviA - - S - - - Protein of unknown function (DUF421)
MKNOAAOH_01208 3e-36 - - - S - - - Protein of unknown function (DUF3290)
MKNOAAOH_01209 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
MKNOAAOH_01210 0.0 - - - S - - - membrane
MKNOAAOH_01211 4.3e-104 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MKNOAAOH_01212 1.17e-266 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
MKNOAAOH_01213 3.93e-127 yqjQ - - S ko:K07124 - ko00000 Enoyl-(Acyl carrier protein) reductase
MKNOAAOH_01214 3.04e-179 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MKNOAAOH_01216 9.68e-22 - - - - - - - -
MKNOAAOH_01217 8.36e-254 oatA - - I - - - Acyltransferase
MKNOAAOH_01218 1.65e-272 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MKNOAAOH_01219 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MKNOAAOH_01220 2.44e-178 - 1.1.1.29 - C ko:K00018 ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MKNOAAOH_01223 2.57e-53 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
MKNOAAOH_01224 4.41e-94 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MKNOAAOH_01225 5.86e-78 yslB - - S - - - Protein of unknown function (DUF2507)
MKNOAAOH_01226 5.23e-54 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
MKNOAAOH_01227 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MKNOAAOH_01228 3.86e-20 cvpA - - S - - - Colicin V production protein
MKNOAAOH_01229 3.67e-17 - - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MKNOAAOH_01230 4.23e-44 yrzB - - S - - - Belongs to the UPF0473 family
MKNOAAOH_01231 3.16e-78 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MKNOAAOH_01232 2.44e-49 yrzL - - S - - - Belongs to the UPF0297 family
MKNOAAOH_01233 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MKNOAAOH_01234 4.29e-236 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MKNOAAOH_01235 1.25e-153 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
MKNOAAOH_01236 3.5e-18 - - - - - - - -
MKNOAAOH_01237 7.88e-184 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MKNOAAOH_01238 3.13e-85 lutC - - S ko:K00782 - ko00000 LUD domain
MKNOAAOH_01239 4.95e-311 lutB - - C ko:K18929 - ko00000 4Fe-4S dicluster domain
MKNOAAOH_01240 3.54e-150 lutA - - C ko:K18928 - ko00000 Cysteine-rich domain
MKNOAAOH_01241 2.92e-264 - - - E ko:K03294 - ko00000 Amino Acid
MKNOAAOH_01243 3.61e-79 uspA3 - - T - - - universal stress protein
MKNOAAOH_01245 1.06e-20 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 protein transport
MKNOAAOH_01246 5.96e-263 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MKNOAAOH_01247 2.88e-231 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MKNOAAOH_01248 1.45e-193 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MKNOAAOH_01249 2.19e-91 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MKNOAAOH_01250 1.41e-287 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MKNOAAOH_01251 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MKNOAAOH_01252 4.38e-256 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
MKNOAAOH_01253 1.84e-203 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MKNOAAOH_01254 2.09e-111 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MKNOAAOH_01255 7.25e-85 ymfM - - S ko:K15539 - ko00000 Helix-turn-helix domain
MKNOAAOH_01256 5.2e-116 ymfI 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
MKNOAAOH_01257 2.81e-184 ymfH - - S - - - Peptidase M16
MKNOAAOH_01258 1.2e-135 ymfF - - S - - - Peptidase M16 inactive domain protein
MKNOAAOH_01259 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
MKNOAAOH_01260 2.62e-111 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MKNOAAOH_01261 2.88e-124 rrmA 2.1.1.187 - H ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 Methyltransferase
MKNOAAOH_01262 8.29e-83 - - - J ko:K03976 - ko00000,ko01000,ko03016 Aminoacyl-tRNA editing domain
MKNOAAOH_01263 1.61e-207 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MKNOAAOH_01264 7e-250 gltT - - U ko:K03309,ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MKNOAAOH_01265 8.5e-24 cutC - - P ko:K06201 - ko00000 Participates in the control of copper homeostasis
MKNOAAOH_01266 1.53e-163 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
MKNOAAOH_01267 1.59e-38 srlB 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
MKNOAAOH_01268 1.1e-284 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MKNOAAOH_01269 2.27e-87 ybbR - - S - - - YbbR-like protein
MKNOAAOH_01270 1.95e-162 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MKNOAAOH_01271 3.92e-92 - - - S - - - Protein of unknown function (DUF1361)
MKNOAAOH_01272 2.46e-145 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
MKNOAAOH_01273 2.74e-89 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
MKNOAAOH_01274 7.04e-73 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
MKNOAAOH_01275 7.01e-181 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
MKNOAAOH_01276 1.52e-134 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MKNOAAOH_01277 1.18e-148 ycsE - - S - - - Sucrose-6F-phosphate phosphohydrolase
MKNOAAOH_01278 3.91e-53 - - - - - - - -
MKNOAAOH_01279 4.3e-91 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MKNOAAOH_01280 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MKNOAAOH_01281 1.19e-32 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
MKNOAAOH_01282 6.32e-224 eriC - - P ko:K03281 - ko00000 chloride
MKNOAAOH_01283 5.39e-189 - - - E - - - Major Facilitator Superfamily
MKNOAAOH_01284 8.04e-212 yclK - - T - - - Histidine kinase
MKNOAAOH_01285 1.95e-134 yclJ - - K ko:K02483 - ko00000,ko02022 response regulator
MKNOAAOH_01286 1.23e-168 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MKNOAAOH_01287 4.33e-298 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MKNOAAOH_01288 9.95e-165 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MKNOAAOH_01289 1.99e-264 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
MKNOAAOH_01290 1.19e-231 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MKNOAAOH_01291 1.59e-174 cggR - - K ko:K05311 - ko00000,ko03000 Putative sugar-binding domain
MKNOAAOH_01293 2.07e-128 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MKNOAAOH_01294 2.05e-191 whiA - - K ko:K09762 - ko00000 May be required for sporulation
MKNOAAOH_01295 9.11e-195 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
MKNOAAOH_01296 7.15e-161 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
MKNOAAOH_01297 4.6e-101 - - - GM - - - NAD dependent epimerase dehydratase family protein
MKNOAAOH_01298 1.23e-107 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MKNOAAOH_01299 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MKNOAAOH_01300 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MKNOAAOH_01301 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
MKNOAAOH_01302 2.89e-143 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MKNOAAOH_01303 1.76e-169 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MKNOAAOH_01304 2.17e-35 yvlD - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
MKNOAAOH_01305 1.02e-10 - - - K ko:K03973 - ko00000,ko02048,ko03000 PspC domain
MKNOAAOH_01306 5.23e-104 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MKNOAAOH_01307 1.03e-110 phoP - - K ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
MKNOAAOH_01308 4.95e-81 minJ - - O - - - Domain present in PSD-95, Dlg, and ZO-1/2.
MKNOAAOH_01309 4.56e-207 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MKNOAAOH_01310 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MKNOAAOH_01311 1.95e-119 yycB - - P ko:K03449 - ko00000,ko02000 Major Facilitator Superfamily
MKNOAAOH_01312 7.08e-105 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MKNOAAOH_01313 4.87e-65 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
MKNOAAOH_01314 2.14e-159 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
MKNOAAOH_01315 3.75e-200 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 transferase
MKNOAAOH_01316 0.0 ydaO - - E - - - amino acid
MKNOAAOH_01317 0.0 - - - P ko:K12952 - ko00000,ko01000 COG COG0474 Cation transport ATPase
MKNOAAOH_01318 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MKNOAAOH_01319 1.7e-46 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MKNOAAOH_01320 7.13e-42 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
MKNOAAOH_01321 1.52e-126 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MKNOAAOH_01322 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
MKNOAAOH_01323 5.06e-206 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MKNOAAOH_01324 1.9e-19 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
MKNOAAOH_01325 5.25e-88 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
MKNOAAOH_01326 8.09e-178 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 Asparaginase
MKNOAAOH_01327 9.93e-104 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
MKNOAAOH_01328 2.83e-120 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MKNOAAOH_01329 3.85e-52 yabA - - L - - - Involved in initiation control of chromosome replication
MKNOAAOH_01330 2.31e-105 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
MKNOAAOH_01331 1.53e-83 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MKNOAAOH_01332 4.16e-39 yaaL - - S - - - Protein of unknown function (DUF2508)
MKNOAAOH_01333 6.62e-126 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MKNOAAOH_01334 3.8e-52 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MKNOAAOH_01335 3.13e-267 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MKNOAAOH_01336 1.11e-80 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MKNOAAOH_01337 3.19e-96 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
MKNOAAOH_01338 1.36e-37 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
MKNOAAOH_01339 1.81e-58 nrdI - - F ko:K03647 - ko00000 NrdI Flavodoxin like
MKNOAAOH_01340 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MKNOAAOH_01341 1.1e-203 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MKNOAAOH_01342 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MKNOAAOH_01343 7.33e-71 - - - - - - - -
MKNOAAOH_01344 2.18e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MKNOAAOH_01345 2.21e-97 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MKNOAAOH_01346 9.98e-150 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MKNOAAOH_01347 2.58e-88 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MKNOAAOH_01348 3.13e-109 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
MKNOAAOH_01349 3.08e-16 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MKNOAAOH_01350 3.3e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
MKNOAAOH_01351 3.89e-92 yacP - - S ko:K06962 - ko00000 YacP-like NYN domain
MKNOAAOH_01352 2.29e-139 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MKNOAAOH_01353 3.45e-73 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MKNOAAOH_01354 1.85e-262 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
MKNOAAOH_01355 2.11e-312 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MKNOAAOH_01356 1.38e-195 yacL - - S - - - domain protein
MKNOAAOH_01357 1.38e-284 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MKNOAAOH_01358 4.81e-95 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
MKNOAAOH_01359 1.17e-25 HA62_12640 - - S ko:K06975 - ko00000 GCN5-related N-acetyl-transferase
MKNOAAOH_01360 6.03e-280 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
MKNOAAOH_01361 2.56e-45 - - - S - - - Enterocin A Immunity
MKNOAAOH_01362 5.83e-109 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MKNOAAOH_01363 4.29e-163 - - - S ko:K07088 - ko00000 Sodium Bile acid symporter family
MKNOAAOH_01364 1.08e-147 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MKNOAAOH_01366 2.41e-56 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
MKNOAAOH_01367 7.99e-316 tex - - K ko:K06959 - ko00000 Tex-like protein N-terminal domain protein
MKNOAAOH_01368 3.23e-166 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MKNOAAOH_01369 3.1e-307 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MKNOAAOH_01370 4.05e-114 tagA 2.4.1.187 GT26 F ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
MKNOAAOH_01371 9.25e-124 yvoA_2 - - K ko:K03710 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
MKNOAAOH_01372 3.02e-115 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MKNOAAOH_01375 4.29e-260 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
MKNOAAOH_01377 5.34e-31 - - - - - - - -
MKNOAAOH_01378 1.4e-120 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
MKNOAAOH_01379 2.24e-16 - 3.5.1.28 CBM50 M ko:K22409 - ko00000,ko01000 Lysin motif
MKNOAAOH_01380 5.63e-195 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
MKNOAAOH_01381 3.03e-183 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
MKNOAAOH_01382 2.18e-69 ykuP - - C ko:K03839 - ko00000 Flavodoxin
MKNOAAOH_01383 5.64e-69 gtcA - - S - - - Teichoic acid glycosylation protein
MKNOAAOH_01384 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
MKNOAAOH_01385 9.8e-152 - 4.3.1.12 - E ko:K01750 ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230 ko00000,ko00001,ko01000 Ornithine cyclodeaminase/mu-crystallin family
MKNOAAOH_01386 1.31e-154 - - - S - - - Sulfite exporter TauE/SafE
MKNOAAOH_01387 2.43e-90 - - - K - - - Sugar-specific transcriptional regulator TrmB
MKNOAAOH_01388 1.35e-213 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MKNOAAOH_01389 1.22e-229 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 Thermophilic metalloprotease (M29)
MKNOAAOH_01390 0.0 - - - E - - - Amino acid permease
MKNOAAOH_01391 9.38e-110 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
MKNOAAOH_01392 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
MKNOAAOH_01393 7.71e-95 - 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
MKNOAAOH_01394 3.51e-270 - - - G ko:K16211 - ko00000,ko02000 Transporter, major facilitator family protein
MKNOAAOH_01395 4.67e-126 malR1 - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
MKNOAAOH_01396 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
MKNOAAOH_01399 1.19e-201 yfmL - - L - - - DEAD DEAH box helicase
MKNOAAOH_01400 1.08e-160 mocA - - S - - - Oxidoreductase
MKNOAAOH_01401 7.99e-33 - - - S - - - Domain of unknown function (DUF4828)
MKNOAAOH_01402 1.14e-213 malZ 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31 G ko:K01187,ko:K01200 ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
MKNOAAOH_01403 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
MKNOAAOH_01404 7.4e-243 glgA 2.4.1.21 GT5 F ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
MKNOAAOH_01405 9.63e-158 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
MKNOAAOH_01406 2.38e-209 glgC 2.7.7.27 - H ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MKNOAAOH_01407 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MKNOAAOH_01408 3.59e-273 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
MKNOAAOH_01409 2.89e-43 - - - O - - - ADP-ribosylglycohydrolase
MKNOAAOH_01410 1.02e-277 gdhA 1.4.1.3, 1.4.1.4 - E ko:K00261,ko:K00262 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 ko00000,ko00001,ko00002,ko01000,ko04147 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
MKNOAAOH_01411 4.59e-262 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
MKNOAAOH_01412 9.28e-42 - - - K - - - GNAT family
MKNOAAOH_01413 1.96e-54 - - - - - - - -
MKNOAAOH_01415 4.23e-227 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
MKNOAAOH_01416 6.89e-118 yjbO 5.4.99.23 - G ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
MKNOAAOH_01417 2.54e-148 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MKNOAAOH_01418 1.58e-123 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
MKNOAAOH_01419 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 This gene contains a nucleotide ambiguity which may be the result of a sequencing error
MKNOAAOH_01420 7.98e-49 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
MKNOAAOH_01421 1.28e-253 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
MKNOAAOH_01422 5.57e-96 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MKNOAAOH_01423 3.17e-78 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
MKNOAAOH_01424 1.63e-81 - - - S - - - ECF transporter, substrate-specific component
MKNOAAOH_01425 1.24e-161 mleP2 - - S ko:K07088 - ko00000 Sodium Bile acid symporter family
MKNOAAOH_01426 3.4e-313 mleS 1.1.1.38, 4.1.1.101 - C ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme
MKNOAAOH_01427 3.21e-89 mleR - - K - - - LysR family
MKNOAAOH_01428 5.18e-74 napB - - K - - - transcriptional
MKNOAAOH_01429 3.34e-52 - - - K - - - Bacterial regulatory proteins, tetR family
MKNOAAOH_01430 2.3e-78 usp2 - - T - - - Belongs to the universal stress protein A family
MKNOAAOH_01431 1.76e-58 atkY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor CopY TcrY
MKNOAAOH_01432 3e-147 - - - M - - - Rib/alpha-like repeat
MKNOAAOH_01433 3.1e-130 - - - M - - - Rib/alpha-like repeat
MKNOAAOH_01435 1.7e-129 ypuA - - S - - - Protein of unknown function (DUF1002)
MKNOAAOH_01436 1.28e-76 apl 3.1.3.1 - S ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 SNARE associated Golgi protein
MKNOAAOH_01437 1.32e-204 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MKNOAAOH_01438 1.34e-51 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
MKNOAAOH_01439 3.63e-267 - - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
MKNOAAOH_01440 4.81e-250 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
MKNOAAOH_01441 7.52e-302 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MKNOAAOH_01442 4.82e-20 - - - S ko:K09790 - ko00000 Protein of unknown function (DUF454)
MKNOAAOH_01443 2.02e-221 - 1.8.1.7 - C ko:K00383,ko:K21739 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Pyridine nucleotide-disulfide oxidoreductase
MKNOAAOH_01444 6e-76 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MKNOAAOH_01445 2.11e-122 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MKNOAAOH_01446 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
MKNOAAOH_01447 8.83e-93 ywlG - - S - - - Belongs to the UPF0340 family
MKNOAAOH_01448 4.21e-82 - - - S - - - Acetyltransferase (GNAT) domain
MKNOAAOH_01450 4.9e-67 - - - K - - - Cro/C1-type HTH DNA-binding domain
MKNOAAOH_01451 3.09e-205 spoVK - - O - - - ATPase family associated with various cellular activities (AAA)
MKNOAAOH_01454 1.08e-156 - - - S - - - Bacteriophage abortive infection AbiH
MKNOAAOH_01455 3.77e-107 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain protein
MKNOAAOH_01456 1.94e-47 - 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
MKNOAAOH_01457 2.54e-200 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 cog cog0286
MKNOAAOH_01458 0.0 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
MKNOAAOH_01459 3.6e-27 - - - K - - - Cro/C1-type HTH DNA-binding domain
MKNOAAOH_01460 5.08e-89 - - - L - - - AAA domain
MKNOAAOH_01461 3.16e-09 - - - - - - - -
MKNOAAOH_01462 4.38e-26 - - - - - - - -
MKNOAAOH_01463 1.16e-95 rha - - K - - - phage regulatory protein, rha family
MKNOAAOH_01465 4.47e-154 - - - L ko:K07448 - ko00000,ko02048 Mrr N-terminal domain
MKNOAAOH_01466 6.39e-267 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MKNOAAOH_01467 5.09e-183 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
MKNOAAOH_01468 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MKNOAAOH_01469 5.93e-294 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MKNOAAOH_01470 1.34e-50 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MKNOAAOH_01471 1.39e-204 camS - - S - - - sex pheromone
MKNOAAOH_01472 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MKNOAAOH_01473 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
MKNOAAOH_01474 1.64e-182 purK2 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MKNOAAOH_01478 5.34e-31 - - - - - - - -
MKNOAAOH_01479 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
MKNOAAOH_01480 2.4e-214 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MKNOAAOH_01481 4.39e-165 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MKNOAAOH_01482 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MKNOAAOH_01483 2.49e-100 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
MKNOAAOH_01484 9.26e-119 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MKNOAAOH_01485 8.52e-60 yabR - - J ko:K07571 - ko00000 RNA binding
MKNOAAOH_01486 1.49e-28 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
MKNOAAOH_01487 1.1e-42 yabO - - J - - - S4 domain protein
MKNOAAOH_01488 6.6e-173 yabM - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
MKNOAAOH_01489 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MKNOAAOH_01490 3.56e-96 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MKNOAAOH_01491 4.72e-201 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
MKNOAAOH_01492 2.2e-110 - - - S - - - (CBS) domain
MKNOAAOH_01493 4.44e-180 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MKNOAAOH_01494 4.09e-261 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MKNOAAOH_01495 1.43e-68 perR - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
MKNOAAOH_01496 8.18e-73 - - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
MKNOAAOH_01497 6.85e-130 sbcC - - L ko:K03546 - ko00000,ko03400 Putative exonuclease SbcCD, C subunit
MKNOAAOH_01498 1.25e-143 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
MKNOAAOH_01499 1.92e-60 - - - M - - - LysM domain protein
MKNOAAOH_01500 0.0 spxB 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
MKNOAAOH_01501 6.4e-111 aad 3.4.13.22 - E ko:K08641 ko01502,ko02020,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
MKNOAAOH_01502 2.42e-42 - - - K - - - transcriptional regulator (TetR family)
MKNOAAOH_01503 9.3e-140 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
MKNOAAOH_01504 9.44e-113 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MKNOAAOH_01505 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
MKNOAAOH_01506 9.85e-308 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
MKNOAAOH_01508 2.29e-79 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
MKNOAAOH_01509 1.04e-99 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MKNOAAOH_01510 6.22e-160 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MKNOAAOH_01511 3.1e-138 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MKNOAAOH_01512 8.76e-140 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MKNOAAOH_01513 2.27e-127 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MKNOAAOH_01514 4.47e-71 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
MKNOAAOH_01515 1.93e-198 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MKNOAAOH_01516 1.24e-82 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MKNOAAOH_01517 7.34e-74 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MKNOAAOH_01518 1.72e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
MKNOAAOH_01519 7.16e-47 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MKNOAAOH_01520 8.94e-143 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MKNOAAOH_01521 1.05e-266 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MKNOAAOH_01522 1.13e-88 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
MKNOAAOH_01523 1.65e-31 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
MKNOAAOH_01524 2.08e-106 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MKNOAAOH_01525 2.4e-73 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MKNOAAOH_01526 4.99e-113 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MKNOAAOH_01527 5.17e-86 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MKNOAAOH_01528 4.1e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MKNOAAOH_01529 1.61e-119 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MKNOAAOH_01530 3.84e-62 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MKNOAAOH_01531 2.98e-78 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MKNOAAOH_01532 5.05e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MKNOAAOH_01533 2.63e-32 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
MKNOAAOH_01534 8.95e-95 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MKNOAAOH_01535 1.62e-149 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MKNOAAOH_01536 9.15e-72 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MKNOAAOH_01537 5.93e-60 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MKNOAAOH_01538 9.24e-183 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MKNOAAOH_01539 1.34e-52 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MKNOAAOH_01540 6.55e-130 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
MKNOAAOH_01541 2.82e-140 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MKNOAAOH_01542 3.24e-66 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
MKNOAAOH_01543 7.36e-219 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MKNOAAOH_01544 6.12e-100 - - - K - - - rpiR family
MKNOAAOH_01545 1.15e-68 rpiA1 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
MKNOAAOH_01546 5.86e-188 XK27_10475 - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
MKNOAAOH_01547 2.79e-14 - - - K - - - Acetyltransferase (GNAT) domain
MKNOAAOH_01548 5.79e-240 steT - - E ko:K03294 - ko00000 amino acid
MKNOAAOH_01549 1.88e-104 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MKNOAAOH_01550 4.89e-111 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MKNOAAOH_01551 2.79e-125 peb1A - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MKNOAAOH_01552 7.01e-132 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MKNOAAOH_01553 1.32e-17 - - - - - - - -
MKNOAAOH_01554 9.05e-123 - - - - - - - -
MKNOAAOH_01555 2.09e-16 - 3.2.1.14 GH18 - ko:K01183 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 -
MKNOAAOH_01556 2.87e-68 zur - - P ko:K02076,ko:K03711 - ko00000,ko03000 Belongs to the Fur family
MKNOAAOH_01557 1.24e-268 yhdG - - E ko:K03294 - ko00000 Amino Acid
MKNOAAOH_01558 5.89e-316 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MKNOAAOH_01559 0.0 - - - L - - - Helicase C-terminal domain protein
MKNOAAOH_01560 1.77e-101 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
MKNOAAOH_01561 6.84e-232 yhdP - - S - - - Transporter associated domain
MKNOAAOH_01562 1.57e-32 - - - - - - - -
MKNOAAOH_01563 5.82e-97 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
MKNOAAOH_01564 1.13e-162 - - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
MKNOAAOH_01565 1.13e-125 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
MKNOAAOH_01566 1.28e-90 hlyD3 - - M ko:K02005 - ko00000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MKNOAAOH_01567 6.88e-200 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
MKNOAAOH_01568 2.8e-174 - - - V - - - MatE
MKNOAAOH_01569 2.66e-57 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MKNOAAOH_01570 5.52e-111 - - - S - - - Alpha beta hydrolase
MKNOAAOH_01571 5.27e-122 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MKNOAAOH_01572 5.23e-219 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
MKNOAAOH_01573 4.34e-138 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Peptidase dimerisation domain
MKNOAAOH_01574 9.04e-131 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
MKNOAAOH_01575 8.54e-45 XK27_01315 - - S - - - Protein of unknown function (DUF2829)
MKNOAAOH_01576 1.09e-68 ccl - - S - - - QueT transporter
MKNOAAOH_01578 5.34e-83 - - - S - - - Uncharacterised protein, DegV family COG1307
MKNOAAOH_01579 1.18e-28 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MKNOAAOH_01580 3.11e-28 crcB1 - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MKNOAAOH_01581 7.86e-46 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
MKNOAAOH_01582 2.09e-110 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
MKNOAAOH_01583 3.06e-157 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
MKNOAAOH_01584 3.42e-65 - - - S - - - Threonine/Serine exporter, ThrE
MKNOAAOH_01585 2.35e-47 - - - S - - - Putative threonine/serine exporter
MKNOAAOH_01586 1.93e-47 - - - S - - - Putative threonine/serine exporter
MKNOAAOH_01587 1.37e-37 cspC - - K ko:K03704 - ko00000,ko03000 Cold shock protein
MKNOAAOH_01588 3.57e-115 mntR - - K ko:K03709 - ko00000,ko03000 Helix-turn-helix diphteria tox regulatory element
MKNOAAOH_01589 5.83e-117 yjbO 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
MKNOAAOH_01590 2.39e-27 - - - - - - - -
MKNOAAOH_01591 9.17e-75 - 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 phosphatase
MKNOAAOH_01592 4.48e-24 - - - - - - - -
MKNOAAOH_01593 5.6e-80 - - - I - - - alpha/beta hydrolase fold
MKNOAAOH_01594 2.61e-52 - - - S - - - branched-chain amino acid
MKNOAAOH_01595 1.78e-132 - - - E - - - AzlC protein
MKNOAAOH_01596 1.28e-24 - - - - - - - -
MKNOAAOH_01597 6.22e-164 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
MKNOAAOH_01598 7.9e-135 yhgE - - V ko:K01421 - ko00000 domain protein
MKNOAAOH_01600 0.000248 - - - S - - - zinc-ribbon domain
MKNOAAOH_01603 1e-53 - - - S - - - virion core protein, lumpy skin disease virus
MKNOAAOH_01604 5.02e-158 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MKNOAAOH_01605 3.84e-218 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
MKNOAAOH_01606 2.26e-148 ydbI - - K - - - AI-2E family transporter
MKNOAAOH_01607 5.39e-74 - - - EG - - - EamA-like transporter family
MKNOAAOH_01608 4.55e-98 nt5e 3.1.3.18 - L ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 haloacid dehalogenase-like hydrolase
MKNOAAOH_01609 3.96e-147 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
MKNOAAOH_01610 4.1e-85 - 1.5.1.38 - S ko:K00299 ko00740,ko00920,ko01100,map00740,map00920,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
MKNOAAOH_01611 7.62e-234 - - - L - - - Probable transposase
MKNOAAOH_01612 1.55e-208 - - - C - - - Luciferase-like monooxygenase
MKNOAAOH_01613 6.93e-55 hxlR - - K - - - Transcriptional regulator, HxlR family
MKNOAAOH_01614 6.68e-219 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
MKNOAAOH_01615 8.92e-134 gntR - - K - - - UbiC transcription regulator-associated domain protein
MKNOAAOH_01616 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
MKNOAAOH_01617 5.94e-107 pncA - - Q - - - isochorismatase
MKNOAAOH_01618 1.14e-81 pgm1 - - G - - - phosphoglycerate mutase
MKNOAAOH_01619 0.0 treB - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MKNOAAOH_01620 2.77e-107 treR - - K ko:K03486 - ko00000,ko03000 UTRA
MKNOAAOH_01621 8.27e-316 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
MKNOAAOH_01622 2.11e-211 mdtG2 - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
MKNOAAOH_01624 3.99e-227 XK27_08315 - - M - - - Sulfatase
MKNOAAOH_01625 3.55e-65 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
MKNOAAOH_01626 4.64e-113 thrB 2.7.1.39 - F ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MKNOAAOH_01627 2.54e-214 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
MKNOAAOH_01628 2.1e-161 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MKNOAAOH_01629 8.47e-223 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
MKNOAAOH_01630 5.24e-98 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MKNOAAOH_01632 4.25e-58 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
MKNOAAOH_01633 1.43e-141 - - - L ko:K07484 - ko00000 Transposase IS66 family
MKNOAAOH_01634 2.31e-176 XK27_08315 - - M - - - Sulfatase
MKNOAAOH_01635 4.93e-148 - - - S - - - Bacterial membrane protein YfhO
MKNOAAOH_01636 1.06e-120 - - - S - - - Bacterial membrane protein, YfhO
MKNOAAOH_01637 4.72e-09 - - - S - - - Psort location CytoplasmicMembrane, score
MKNOAAOH_01638 2.69e-53 - - - S - - - Bacterial membrane protein, YfhO
MKNOAAOH_01639 4.55e-20 - - - - - - - -
MKNOAAOH_01640 3e-36 - - - S - - - Psort location CytoplasmicMembrane, score
MKNOAAOH_01641 8.65e-185 iunH3 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Inosine-uridine preferring nucleoside hydrolase
MKNOAAOH_01642 2.11e-67 - - - T ko:K16923 - ko00000,ko00002,ko02000 phosphorelay sensor kinase activity
MKNOAAOH_01643 3.39e-195 XK27_09615 1.5.1.36 - S ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 reductase
MKNOAAOH_01644 8.69e-86 - - - S - - - NADPH-dependent FMN reductase
MKNOAAOH_01646 4.25e-58 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
MKNOAAOH_01647 1.43e-141 - - - L ko:K07484 - ko00000 Transposase IS66 family
MKNOAAOH_01648 1.5e-118 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
MKNOAAOH_01649 4.6e-205 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MKNOAAOH_01650 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
MKNOAAOH_01651 5.12e-39 gtcA - - S - - - Teichoic acid glycosylation protein
MKNOAAOH_01652 2.86e-145 - - - M - - - Glycosyl transferase family 2
MKNOAAOH_01653 2.32e-28 - - - S - - - Psort location CytoplasmicMembrane, score 10.00
MKNOAAOH_01654 2.63e-95 - - - - - - - -
MKNOAAOH_01655 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
MKNOAAOH_01656 2.25e-170 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
MKNOAAOH_01657 1.12e-55 - - - E - - - GDSL-like Lipase/Acylhydrolase
MKNOAAOH_01658 3.91e-143 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MKNOAAOH_01659 2.45e-241 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
MKNOAAOH_01660 1.26e-268 potE - - E - - - Amino Acid
MKNOAAOH_01661 1.24e-43 - - - S - - - MazG nucleotide pyrophosphohydrolase domain
MKNOAAOH_01662 1.53e-168 tetA - - EGP ko:K08151,ko:K08153,ko:K19576,ko:K19578 - ko00000,ko00002,ko01504,ko02000 Major facilitator Superfamily
MKNOAAOH_01664 4.25e-58 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
MKNOAAOH_01665 1.43e-141 - - - L ko:K07484 - ko00000 Transposase IS66 family
MKNOAAOH_01667 1.36e-80 - - - D - - - Peptidase family M23
MKNOAAOH_01668 1.31e-91 - - - M - - - transferase activity, transferring glycosyl groups
MKNOAAOH_01669 2.69e-68 - - - - - - - -
MKNOAAOH_01670 2.62e-202 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
MKNOAAOH_01671 1.12e-62 - - GT2 M ko:K12997 - ko00000,ko01000,ko01003,ko01005 Glycosyl transferase, family 2
MKNOAAOH_01672 9.57e-248 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
MKNOAAOH_01673 5.92e-120 - - - M - - - Core-2/I-Branching enzyme
MKNOAAOH_01674 5.92e-116 epsE2 - - M - - - Bacterial sugar transferase
MKNOAAOH_01675 1.15e-162 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
MKNOAAOH_01676 5.99e-142 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
MKNOAAOH_01677 3.85e-118 ywqD - - D - - - Capsular exopolysaccharide family
MKNOAAOH_01678 2.84e-98 epsB - - M - - - biosynthesis protein
MKNOAAOH_01679 4.01e-270 ugd 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 UDP binding domain
MKNOAAOH_01681 1.15e-60 - - - L ko:K07484 - ko00000 Transposase IS66 family
MKNOAAOH_01682 1.43e-141 - - - L ko:K07484 - ko00000 Transposase IS66 family
MKNOAAOH_01683 4.25e-58 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
MKNOAAOH_01685 2.24e-51 - - - S - - - Acyltransferase family
MKNOAAOH_01686 4.66e-163 - - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
MKNOAAOH_01687 1.52e-18 - - - S - - - Hexapeptide repeat of succinyl-transferase
MKNOAAOH_01688 6.97e-52 - - - M - - - Glycosyltransferase like family 2
MKNOAAOH_01691 1.97e-05 yibD - GT2 M ko:K19354 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferases involved in cell wall biogenesis
MKNOAAOH_01692 3.41e-178 - - - M - - - Glycosyl transferase family 2
MKNOAAOH_01693 9.62e-82 - - - S - - - Hexapeptide repeat of succinyl-transferase
MKNOAAOH_01694 1.17e-146 - - - G - - - Glycosyltransferase Family 4
MKNOAAOH_01695 1.73e-219 wchF - GT4 M ko:K12996 - ko00000,ko01000,ko01003,ko01005 Domain of unknown function (DUF1972)
MKNOAAOH_01697 2.04e-112 tcaA - - S ko:K21463 - ko00000 response to antibiotic
MKNOAAOH_01699 7.12e-147 nagZ 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Glycosyl hydrolase family 3 N terminal domain
MKNOAAOH_01700 3.15e-161 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MKNOAAOH_01701 2.56e-213 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MKNOAAOH_01702 2.26e-130 rfbC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
MKNOAAOH_01703 1.71e-184 rfbA 2.7.7.24 - H ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MKNOAAOH_01704 1.45e-79 - - - S - - - Glycosyltransferase like family 2
MKNOAAOH_01705 1.14e-75 - - - S - - - Glycosyltransferase like family 2
MKNOAAOH_01706 7e-149 cps3J - - M - - - Domain of unknown function (DUF4422)
MKNOAAOH_01707 1.3e-47 XK27_07085 - - S ko:K07052 - ko00000 CAAX protease self-immunity
MKNOAAOH_01708 2.62e-114 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
MKNOAAOH_01709 1.03e-81 - - - S - - - Haloacid dehalogenase-like hydrolase
MKNOAAOH_01710 1.04e-190 - - - EGP - - - Major Facilitator
MKNOAAOH_01712 1.34e-88 yagB - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
MKNOAAOH_01713 8.26e-36 adhR - - K - - - transcriptional regulator
MKNOAAOH_01714 1.88e-114 - - - S - - - NADPH-dependent FMN reductase
MKNOAAOH_01715 7.03e-130 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
MKNOAAOH_01716 1.98e-71 - - - S - - - ECF transporter, substrate-specific component
MKNOAAOH_01717 4.23e-139 znuB - - U ko:K02075,ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
MKNOAAOH_01718 1.6e-126 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
MKNOAAOH_01719 5.14e-132 psaA - - P ko:K02077,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
MKNOAAOH_01720 1.52e-45 - - - - - - - -
MKNOAAOH_01721 2.21e-73 - - - S - - - Protein of unknown function (DUF1129)
MKNOAAOH_01722 5.93e-242 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MKNOAAOH_01723 1.48e-31 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
MKNOAAOH_01724 2.06e-138 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
MKNOAAOH_01725 4.97e-153 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
MKNOAAOH_01726 1.24e-103 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
MKNOAAOH_01727 2.97e-129 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
MKNOAAOH_01728 4.74e-161 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
MKNOAAOH_01729 5.26e-88 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Membrane domain of glycerophosphoryl diester phosphodiesterase
MKNOAAOH_01730 0.0 atp2C1 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
MKNOAAOH_01731 6.54e-235 - - - L - - - Probable transposase
MKNOAAOH_01732 1.36e-78 - 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Possible lysine decarboxylase
MKNOAAOH_01733 8.59e-94 - 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 DJ-1/PfpI family
MKNOAAOH_01735 5.09e-83 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
MKNOAAOH_01736 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
MKNOAAOH_01737 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
MKNOAAOH_01738 5e-45 - - - - - - - -
MKNOAAOH_01739 3.93e-180 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MKNOAAOH_01740 2.46e-198 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MKNOAAOH_01741 1.28e-122 proB 2.7.2.11 - F ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MKNOAAOH_01742 2.83e-199 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
MKNOAAOH_01744 4.25e-58 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
MKNOAAOH_01745 1.43e-141 - - - L ko:K07484 - ko00000 Transposase IS66 family
MKNOAAOH_01746 4.21e-53 ybjQ - - S - - - Belongs to the UPF0145 family
MKNOAAOH_01748 1.09e-121 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MKNOAAOH_01749 5.09e-56 - - - K - - - Transcriptional regulator, GntR family
MKNOAAOH_01750 2.44e-235 mtlD 1.1.1.17 - C ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 mannitol-1-phosphate 5-dehydrogenase activity
MKNOAAOH_01751 1.63e-85 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MKNOAAOH_01752 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
MKNOAAOH_01753 6.4e-138 - - - P - - - Integral membrane protein TerC family
MKNOAAOH_01754 3.75e-49 - - - K - - - Transcriptional regulator
MKNOAAOH_01755 9.62e-122 fliY - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
MKNOAAOH_01756 7.11e-129 - - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MKNOAAOH_01757 3.9e-134 tcyB - - E ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MKNOAAOH_01759 1.66e-51 ganB 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
MKNOAAOH_01760 1.44e-236 noxE - - S - - - Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
MKNOAAOH_01761 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MKNOAAOH_01762 2.7e-258 mtlR - - K ko:K03483 - ko00000,ko03000 Mga helix-turn-helix domain
MKNOAAOH_01763 2.84e-220 nhaP3 - - P ko:K03316 - ko00000 Sodium proton antiporter
MKNOAAOH_01764 3.08e-135 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
MKNOAAOH_01765 4.88e-66 dhaM 2.7.1.121 - S ko:K05881 ko00561,map00561 ko00000,ko00001,ko01000,ko02000 PTS system fructose IIA component
MKNOAAOH_01766 2.82e-88 dhaL 2.7.1.121 - S ko:K05879 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak2
MKNOAAOH_01767 2.16e-192 dhaK 2.7.1.121 - G ko:K05878 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak1 domain
MKNOAAOH_01768 5.15e-145 dhaK2 2.7.1.28, 2.7.1.29, 4.6.1.15 - G ko:K00863 ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622 ko00000,ko00001,ko00002,ko01000 Dak1 domain
MKNOAAOH_01769 8.21e-78 XK27_02085 - - K - - - Bacterial regulatory proteins, tetR family
MKNOAAOH_01770 1.23e-265 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
MKNOAAOH_01772 5.69e-142 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
MKNOAAOH_01773 1.85e-96 XK27_02070 - - S ko:K07078 - ko00000 Nitroreductase family
MKNOAAOH_01774 2.17e-240 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 P-type ATPase
MKNOAAOH_01775 1.89e-45 - - - K ko:K21903 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
MKNOAAOH_01776 0.0 l1n 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
MKNOAAOH_01777 7.04e-149 dgk1 2.7.1.76 - F ko:K10353 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 deoxynucleoside kinase
MKNOAAOH_01778 3.96e-76 - - - F - - - Nucleoside 2-deoxyribosyltransferase
MKNOAAOH_01779 1.4e-96 azlC - - E - - - branched-chain amino acid
MKNOAAOH_01780 1.42e-42 - - - S - - - Branched-chain amino acid transport protein (AzlD)
MKNOAAOH_01781 2.21e-73 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
MKNOAAOH_01782 1.8e-69 jag - - S ko:K06346 - ko00000 R3H domain protein
MKNOAAOH_01783 4.55e-68 - - - K - - - Transcriptional regulator C-terminal region
MKNOAAOH_01784 3.54e-59 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
MKNOAAOH_01785 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
MKNOAAOH_01786 7.86e-140 dat 2.6.1.21 - EH ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 PFAM aminotransferase, class IV
MKNOAAOH_01787 3.07e-06 sdpI - - S - - - Protein of unknown function (DUF1648)
MKNOAAOH_01788 1.26e-84 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
MKNOAAOH_01789 1.37e-61 hmpT - - S - - - ECF-type riboflavin transporter, S component
MKNOAAOH_01790 2.78e-54 - - - K - - - Acetyltransferase GNAT Family
MKNOAAOH_01792 0.0 ylbB - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
MKNOAAOH_01793 8.17e-123 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MKNOAAOH_01795 1.11e-93 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MKNOAAOH_01796 5.75e-155 ytbE - - S - - - reductase
MKNOAAOH_01797 1.22e-57 ytcD - - K - - - HxlR-like helix-turn-helix
MKNOAAOH_01798 1.78e-130 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
MKNOAAOH_01799 4.78e-86 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 ABC transporter
MKNOAAOH_01800 1.49e-208 oxlT - - P ko:K08177 - ko00000,ko02000 Major Facilitator Superfamily
MKNOAAOH_01801 5.58e-69 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MKNOAAOH_01802 2.53e-60 - - - S - - - Short repeat of unknown function (DUF308)
MKNOAAOH_01803 4.63e-30 - - - K - - - Transcriptional regulator C-terminal region
MKNOAAOH_01804 2.6e-191 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Peroxidase
MKNOAAOH_01806 2.35e-51 - - - K - - - LytTr DNA-binding domain
MKNOAAOH_01807 1.53e-143 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine S-methyltransferase
MKNOAAOH_01808 9.59e-265 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
MKNOAAOH_01809 5.22e-21 psiE - - S ko:K13256 - ko00000 Phosphate-starvation-inducible E
MKNOAAOH_01810 1.99e-196 oppF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MKNOAAOH_01811 3.5e-229 oppD - - P ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MKNOAAOH_01812 1.06e-216 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MKNOAAOH_01813 1.39e-189 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MKNOAAOH_01814 5.05e-253 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MKNOAAOH_01815 1.85e-278 yifK - - E ko:K03293 - ko00000 Amino acid permease
MKNOAAOH_01816 6.95e-112 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MKNOAAOH_01817 1.14e-69 supH - - S - - - Sucrose-6F-phosphate phosphohydrolase
MKNOAAOH_01818 2.23e-78 pgm3 - - G - - - phosphoglycerate mutase family
MKNOAAOH_01819 6.48e-317 copA 3.6.3.3, 3.6.3.5, 3.6.3.54 - P ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
MKNOAAOH_01820 4.15e-26 - - - S - - - Cupredoxin-like domain
MKNOAAOH_01821 5.2e-57 - - - S - - - Cupredoxin-like domain
MKNOAAOH_01822 3.55e-190 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
MKNOAAOH_01823 1.12e-28 - - - K - - - transcriptional regulator
MKNOAAOH_01824 2.64e-98 - - - S - - - intracellular protease amidase
MKNOAAOH_01825 9.64e-168 glpQ4 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Glycerophosphoryl diester phosphodiesterase family
MKNOAAOH_01826 1.41e-142 - - - K - - - helix_turn _helix lactose operon repressor
MKNOAAOH_01827 2.92e-291 treC - - G - - - Psort location Cytoplasmic, score
MKNOAAOH_01828 2.02e-51 - 2.7.1.191 - G ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
MKNOAAOH_01829 1.18e-157 - - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
MKNOAAOH_01830 7.67e-139 - - - G - - - PTS system sorbose-specific iic component
MKNOAAOH_01831 1.32e-84 - - - G - - - PTS system sorbose subfamily IIB component
MKNOAAOH_01832 4.75e-102 metA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
MKNOAAOH_01833 8e-176 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
MKNOAAOH_01834 2.42e-254 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
MKNOAAOH_01835 5.1e-149 pepL 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
MKNOAAOH_01836 1.54e-243 - - - C - - - FMN_bind
MKNOAAOH_01837 1.13e-70 oxyR5 - - K - - - Transcriptional regulator
MKNOAAOH_01838 2.56e-203 adhB 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
MKNOAAOH_01839 1.4e-247 metY 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
MKNOAAOH_01840 1.14e-92 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
MKNOAAOH_01841 2.6e-166 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Cobalamin-independent synthase, Catalytic domain
MKNOAAOH_01842 5.93e-128 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
MKNOAAOH_01843 1.36e-103 XK27_08125 - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
MKNOAAOH_01844 5.3e-12 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
MKNOAAOH_01845 2e-77 ykhA 3.1.2.20 - I ko:K01073 - ko00000,ko01000 Thioesterase superfamily
MKNOAAOH_01846 4.97e-199 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MKNOAAOH_01848 4.09e-291 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MKNOAAOH_01849 7.69e-274 - - - L - - - PFAM RNA-directed DNA polymerase (Reverse transcriptase)
MKNOAAOH_01850 6.89e-82 - - - C - - - FMN binding
MKNOAAOH_01851 1.18e-258 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
MKNOAAOH_01852 9.07e-86 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
MKNOAAOH_01853 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
MKNOAAOH_01867 5.34e-31 - - - - - - - -
MKNOAAOH_01870 1.4e-38 - - - S - - - Belongs to the HesB IscA family
MKNOAAOH_01871 1.38e-83 icaB - - G - - - Polysaccharide deacetylase
MKNOAAOH_01873 5e-67 - - - K - - - LysR substrate binding domain
MKNOAAOH_01874 1.66e-152 - - - S - - - Conserved hypothetical protein 698
MKNOAAOH_01875 2.06e-253 nupG - - F ko:K16323 - ko00000,ko02000 Nucleoside
MKNOAAOH_01876 3.78e-138 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MKNOAAOH_01877 8.2e-65 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MKNOAAOH_01878 2.29e-20 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
MKNOAAOH_01879 6.28e-181 xerS - - L ko:K04763 - ko00000,ko03036 Phage integrase family
MKNOAAOH_01880 4.79e-89 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
MKNOAAOH_01881 2.97e-175 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MKNOAAOH_01882 2.95e-271 - 1.3.5.1, 1.3.5.4 - C ko:K00239,ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134 ko00000,ko00001,ko00002,ko01000 FAD binding domain
MKNOAAOH_01883 1.73e-148 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
MKNOAAOH_01884 7.4e-177 - - - G - - - Xylose isomerase-like TIM barrel
MKNOAAOH_01885 9.23e-90 - - - K - - - Transcriptional regulator, LysR family
MKNOAAOH_01886 8.06e-122 - - - EGP - - - Major Facilitator Superfamily
MKNOAAOH_01887 7.6e-168 - - - EGP - - - Major Facilitator Superfamily
MKNOAAOH_01888 2.49e-102 - - - L ko:K07497 - ko00000 Integrase core domain
MKNOAAOH_01889 1.2e-28 - - - L ko:K07483 - ko00000 PFAM transposase IS3 IS911 family protein
MKNOAAOH_01890 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 E1-E2 ATPase
MKNOAAOH_01891 3.43e-45 - - - P - - - Heavy-metal-associated domain
MKNOAAOH_01892 1.43e-17 - - - L ko:K07498 - ko00000 Transposase
MKNOAAOH_01893 5.51e-28 tnp - - - ko:K07498 - ko00000 -
MKNOAAOH_01894 8.94e-55 - - - L ko:K07497 - ko00000 hmm pf00665
MKNOAAOH_01895 5.14e-127 - - - K ko:K21562 - ko00000,ko03000 helix_turn_helix, cAMP Regulatory protein
MKNOAAOH_01896 2.08e-120 - - - P ko:K04047 - ko00000,ko03036 Ferritin-like domain
MKNOAAOH_01897 8.59e-199 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
MKNOAAOH_01898 8.72e-76 - - - L ko:K07491 - ko00000 Transposase IS200 like
MKNOAAOH_01899 1.22e-66 - - - C - - - Oxidoreductase NAD-binding domain
MKNOAAOH_01901 3.22e-140 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 prohibitin homologues
MKNOAAOH_01902 2.48e-34 - - - S - - - protein encoded in hypervariable junctions of pilus gene clusters
MKNOAAOH_01903 0.0 prtB 3.4.21.96 - O ko:K01361 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
MKNOAAOH_01905 1.73e-49 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MKNOAAOH_01906 2.56e-148 - - - O - - - AAA domain (Cdc48 subfamily)
MKNOAAOH_01907 9.08e-86 - - - - - - - -
MKNOAAOH_01910 7.62e-17 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
MKNOAAOH_01911 1.12e-52 agrC 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 ATPase histidine kinase DNA gyrase B HSP90 domain protein
MKNOAAOH_01913 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
MKNOAAOH_01914 3.14e-47 - - - - - - - -
MKNOAAOH_01916 3.22e-161 soj - - D - - - CobQ CobB MinD ParA nucleotide binding domain protein
MKNOAAOH_01917 2.89e-84 licT - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
MKNOAAOH_01918 1.12e-253 crr - - G ko:K02755,ko:K02756,ko:K02757,ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 Pts system
MKNOAAOH_01919 4.61e-213 ascB 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MKNOAAOH_01920 2.46e-46 - - - S - - - Replication initiator protein A (RepA) N-terminus
MKNOAAOH_01921 3.24e-142 - - - L - - - Initiator Replication protein
MKNOAAOH_01925 3.84e-26 - - - L - - - PLD-like domain
MKNOAAOH_01926 1.89e-92 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
MKNOAAOH_01927 8.56e-39 - - - L ko:K07483,ko:K07497 - ko00000 Helix-turn-helix domain
MKNOAAOH_01928 4.16e-127 - - - L - - - PLD-like domain
MKNOAAOH_01930 0.000189 yhaH - - S - - - Protein of unknown function (DUF805)
MKNOAAOH_01932 7.19e-287 fusA1 - - J - - - elongation factor G
MKNOAAOH_01933 3.83e-43 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MKNOAAOH_01934 5.75e-09 - - - - - - - -
MKNOAAOH_01935 1.92e-270 potE - - E - - - Amino Acid
MKNOAAOH_01936 1.05e-79 yphA - - GM - - - NAD dependent epimerase/dehydratase family
MKNOAAOH_01937 8.17e-96 - - - K - - - Helix-turn-helix domain, rpiR family
MKNOAAOH_01938 2.52e-118 nanE 5.1.3.9 - G ko:K01788 ko00520,map00520 ko00000,ko00001,ko01000 Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
MKNOAAOH_01939 8.86e-162 nanA 4.1.3.3 - EM ko:K01639 ko00520,map00520 ko00000,ko00001,ko01000 Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
MKNOAAOH_01940 1.77e-115 nanK - - GK - - - ROK family
MKNOAAOH_01941 7.57e-71 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Belongs to the NDK family
MKNOAAOH_01942 3.08e-75 - - - G - - - Xylose isomerase domain protein TIM barrel
MKNOAAOH_01943 9.37e-193 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MKNOAAOH_01944 1.44e-252 - - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MKNOAAOH_01945 7.81e-96 - - - L ko:K07491 - ko00000 PFAM transposase IS200-family protein
MKNOAAOH_01946 1.1e-95 - 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
MKNOAAOH_01947 1.05e-143 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
MKNOAAOH_01948 5.79e-54 yitW - - S - - - Iron-sulfur cluster assembly protein
MKNOAAOH_01949 2.27e-86 - - - S ko:K08996 - ko00000 Protein of unknown function (DUF1440)
MKNOAAOH_01950 3.26e-103 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Carbon-nitrogen hydrolase
MKNOAAOH_01951 4.02e-237 mtnE - - E ko:K08969 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
MKNOAAOH_01953 8.44e-20 - - - - - - - -
MKNOAAOH_01954 4.22e-113 - - - S - - - Haloacid dehalogenase-like hydrolase
MKNOAAOH_01955 7.3e-48 blpT - - - - - - -
MKNOAAOH_01956 1.3e-08 ps105 - - - - - - -
MKNOAAOH_01965 3.09e-16 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
MKNOAAOH_01966 3.17e-28 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
MKNOAAOH_01967 2.81e-34 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
MKNOAAOH_01968 2.88e-10 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
MKNOAAOH_01973 2.44e-89 - - - L - - - Phage integrase, N-terminal SAM-like domain
MKNOAAOH_01974 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 phosphatase activity
MKNOAAOH_01975 7.09e-11 - - - M - - - domain protein
MKNOAAOH_01976 7.08e-189 - - - M - - - YSIRK type signal peptide
MKNOAAOH_01977 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
MKNOAAOH_01978 6.42e-125 fabK 1.3.1.9 - S ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Nitronate monooxygenase
MKNOAAOH_01979 6.35e-206 ytbD - - EGP ko:K19577 - ko00000,ko02000 Major Facilitator Superfamily
MKNOAAOH_01980 3.37e-141 srlD2 1.1.1.140 - IQ ko:K00068 ko00051,map00051 ko00000,ko00001,ko01000 NAD dependent epimerase/dehydratase family
MKNOAAOH_01981 7.16e-94 srlM - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
MKNOAAOH_01982 7.01e-57 srlM1 - - K - - - Glucitol operon activator protein (GutM)
MKNOAAOH_01983 1.93e-106 srlA - - G ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko02000 PTS system enzyme II sorbitol-specific factor
MKNOAAOH_01984 1.05e-172 srlE 2.7.1.198 - G ko:K02782,ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Sorbitol phosphotransferase enzyme II N-terminus
MKNOAAOH_01985 2.21e-47 pts38A 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
MKNOAAOH_01986 3.58e-79 mipB 2.2.1.2 - H ko:K00616,ko:K08314 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase/Fructose-6-phosphate aldolase
MKNOAAOH_01987 3.14e-147 ddh 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MKNOAAOH_01988 3.83e-173 pfoS/R - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
MKNOAAOH_01990 5.19e-256 bsaB - - S ko:K20483 ko02020,ko02024,map02020,map02024 ko00000,ko00001 Lantibiotic dehydratase, C terminus
MKNOAAOH_01991 1.3e-228 nisT - - V ko:K06147,ko:K20485 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 ATPases associated with a variety of cellular activities
MKNOAAOH_01992 3.76e-91 spaC1 - - V ko:K20484 ko02020,ko02024,map02020,map02024 ko00000,ko00001 Lanthionine synthetase C-like protein
MKNOAAOH_01993 6.55e-113 spaR - - KT ko:K20488 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
MKNOAAOH_01994 5.88e-130 - 2.7.13.3 - T ko:K20487 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 His Kinase A (phosphoacceptor) domain
MKNOAAOH_01995 1.06e-92 - - - V ko:K01990,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
MKNOAAOH_01996 7.58e-43 - - - S - - - ABC-2 family transporter protein
MKNOAAOH_01998 3.04e-36 - - - K - - - Helix-turn-helix XRE-family like proteins
MKNOAAOH_01999 3.32e-26 - - - S - - - protein encoded in hypervariable junctions of pilus gene clusters
MKNOAAOH_02001 2.22e-281 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MKNOAAOH_02002 2.59e-148 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
MKNOAAOH_02003 7.04e-178 sufD - - O ko:K07033,ko:K09015 - ko00000 FeS assembly protein SufD
MKNOAAOH_02004 2.09e-184 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MKNOAAOH_02005 1.15e-53 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
MKNOAAOH_02006 2.63e-303 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
MKNOAAOH_02007 1.77e-63 - - - S - - - VIT family
MKNOAAOH_02008 0.0 pflB 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 Pyruvate formate lyase-like
MKNOAAOH_02009 5.49e-175 pflA 1.97.1.4 - C ko:K04069 - ko00000,ko01000 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MKNOAAOH_02010 7.51e-142 rssA - - S - - - Phospholipase, patatin family
MKNOAAOH_02011 3.76e-18 - - - - - - - -
MKNOAAOH_02012 8.92e-35 - - - - - - - -
MKNOAAOH_02013 3.52e-100 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
MKNOAAOH_02014 1.15e-126 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MKNOAAOH_02015 9.75e-07 lanR - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
MKNOAAOH_02016 1.7e-12 yhaI - - S - - - Protein of unknown function (DUF805)
MKNOAAOH_02018 6.88e-100 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
MKNOAAOH_02019 1.94e-67 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
MKNOAAOH_02020 1.22e-72 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MKNOAAOH_02021 5.82e-98 desR - - K ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, Lux Regulon
MKNOAAOH_02022 3.03e-88 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
MKNOAAOH_02023 2.67e-112 bsh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
MKNOAAOH_02027 2.03e-242 repA - - S - - - Replication initiator protein A
MKNOAAOH_02028 5.03e-35 - - - - - - - -
MKNOAAOH_02029 2.49e-178 - - - S - - - Fic/DOC family
MKNOAAOH_02030 2.83e-58 - - - L - - - Addiction module antitoxin, RelB DinJ family
MKNOAAOH_02031 3.96e-37 - - - - - - - -
MKNOAAOH_02032 1.58e-38 - - - S - - - protein conserved in bacteria
MKNOAAOH_02033 2.13e-93 - - - S - - - protein conserved in bacteria
MKNOAAOH_02034 2.09e-55 - - - - - - - -
MKNOAAOH_02035 1.29e-32 - - - - - - - -
MKNOAAOH_02036 0.0 - - - L - - - MobA MobL family protein
MKNOAAOH_02037 1.94e-40 - - - L - - - MULE transposase domain
MKNOAAOH_02038 4.86e-94 cylA - - V ko:K11050 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
MKNOAAOH_02039 4.18e-75 cylB - - V ko:K11051 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 type transporter
MKNOAAOH_02040 3.13e-35 - - - K ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
MKNOAAOH_02041 2.24e-15 - - - S - - - Protein of unknown function (DUF3021)
MKNOAAOH_02042 2.2e-202 B4168_4126 - - L ko:K07493 - ko00000 Transposase
MKNOAAOH_02043 2.57e-60 B4168_4126 - - L ko:K07493 - ko00000 Transposase
MKNOAAOH_02044 2.44e-104 - - - - - - - -
MKNOAAOH_02045 0.0 - 1.8.1.7 - C ko:K00383,ko:K21739 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Pyridine nucleotide-disulfide oxidoreductase
MKNOAAOH_02046 0.0 - - - M - - - Cna protein B-type domain
MKNOAAOH_02047 7.64e-121 - - - T ko:K16923 - ko00000,ko00002,ko02000 phosphorelay sensor kinase activity
MKNOAAOH_02048 7.21e-169 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
MKNOAAOH_02049 2.42e-200 - - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
MKNOAAOH_02050 2.06e-192 - - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
MKNOAAOH_02051 0.0 proWX - - EM ko:K05845,ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MKNOAAOH_02052 1.56e-229 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MKNOAAOH_02053 2.4e-312 gshR 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
MKNOAAOH_02054 1.41e-129 pinR1 - - L - - - Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
MKNOAAOH_02055 3.97e-136 - - - - - - - -
MKNOAAOH_02056 3.17e-51 - - - S ko:K07473 - ko00000,ko02048 RelB antitoxin
MKNOAAOH_02057 0.0 - - - EGP - - - Major Facilitator
MKNOAAOH_02058 6.8e-140 - - - K - - - Bacterial regulatory proteins, tetR family
MKNOAAOH_02060 2.13e-134 pncA - - Q - - - Isochorismatase family
MKNOAAOH_02061 0.0 nadC2 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MKNOAAOH_02062 8.38e-169 - - - F - - - NUDIX domain
MKNOAAOH_02063 5.57e-80 - - - V - - - HNH endonuclease
MKNOAAOH_02065 1.94e-40 - - - L - - - MULE transposase domain
MKNOAAOH_02066 8.46e-65 - - - D ko:K19159 - ko00000,ko02048 Antitoxin component of a toxin-antitoxin (TA) module
MKNOAAOH_02067 1.74e-74 - - - S - - - Bacterial toxin of type II toxin-antitoxin system, YafQ
MKNOAAOH_02068 6.36e-190 - - - D ko:K03496 - ko00000,ko03036,ko04812 CobQ CobB MinD ParA nucleotide binding domain protein
MKNOAAOH_02069 4.18e-46 - - - - - - - -

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)