ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
HNMJCOBO_00001 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HNMJCOBO_00002 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HNMJCOBO_00003 1.25e-51 yaaB - - S - - - Domain of unknown function (DUF370)
HNMJCOBO_00004 4.54e-264 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HNMJCOBO_00005 2.24e-45 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
HNMJCOBO_00006 9.88e-263 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HNMJCOBO_00007 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HNMJCOBO_00008 5.7e-71 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HNMJCOBO_00009 9.29e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HNMJCOBO_00010 6.14e-140 jag - - S ko:K06346 - ko00000 single-stranded nucleic acid binding R3H
HNMJCOBO_00011 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HNMJCOBO_00012 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HNMJCOBO_00013 1.01e-167 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
HNMJCOBO_00014 9e-193 noc - - D ko:K03497 - ko00000,ko03000,ko03036,ko04812 Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
HNMJCOBO_00015 5.36e-97 - - - S - - - Bacterial PH domain
HNMJCOBO_00016 4.79e-173 soj - - D ko:K03496 - ko00000,ko03036,ko04812 COG1192 ATPases involved in chromosome partitioning
HNMJCOBO_00017 3.96e-191 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
HNMJCOBO_00018 9.15e-145 yyaC - - S - - - Sporulation protein YyaC
HNMJCOBO_00019 2.17e-226 yyaD - - S - - - Membrane
HNMJCOBO_00020 7.41e-45 yyzM - - S - - - protein conserved in bacteria
HNMJCOBO_00021 0.0 yyaE - - C - - - Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HNMJCOBO_00022 5.65e-256 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HNMJCOBO_00023 1.18e-60 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
HNMJCOBO_00024 1.81e-103 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HNMJCOBO_00025 4.25e-49 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HNMJCOBO_00026 1.91e-183 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
HNMJCOBO_00027 5.03e-229 ccpB - - K - - - Transcriptional regulator
HNMJCOBO_00028 2.82e-87 yyaH 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HNMJCOBO_00029 3.13e-128 vatD 2.3.1.28, 2.3.1.79 - S ko:K00638,ko:K00661,ko:K18234 - br01600,ko00000,ko01000,ko01504 Bacterial transferase hexapeptide (six repeats)
HNMJCOBO_00030 0.0 - - - EGP ko:K08369 - ko00000,ko02000 Major facilitator superfamily
HNMJCOBO_00031 1.42e-213 yyaK - - S ko:K07052 - ko00000 CAAX protease self-immunity
HNMJCOBO_00032 0.0 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
HNMJCOBO_00033 1.9e-312 tetL - - EGP ko:K08168 - ko00000,ko00002,ko01504,ko02000 COG0477 Permeases of the major facilitator superfamily
HNMJCOBO_00034 6.07e-137 yyaP - - H - - - RibD C-terminal domain
HNMJCOBO_00035 1.82e-86 - - - S - - - YjbR
HNMJCOBO_00036 4.03e-130 - - - K ko:K19273 - ko00000,ko01000,ko01504 Acetyltransferase (GNAT) domain
HNMJCOBO_00037 8.73e-132 yyaS - - S ko:K07149 - ko00000 Membrane
HNMJCOBO_00038 2.45e-103 yjcF - - S - - - Acetyltransferase (GNAT) domain
HNMJCOBO_00039 4.54e-100 yybA - - K - - - transcriptional
HNMJCOBO_00040 5.29e-165 - - - S - - - Metallo-beta-lactamase superfamily
HNMJCOBO_00041 1.27e-99 yybC - - - - - - -
HNMJCOBO_00042 7.91e-104 yjcF - - S - - - Acetyltransferase (GNAT) domain
HNMJCOBO_00043 1.36e-212 yybE - - K - - - Transcriptional regulator
HNMJCOBO_00044 1.23e-276 yybF - - EGP ko:K08224 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
HNMJCOBO_00045 8.55e-157 yybG - - S - - - Pentapeptide repeat-containing protein
HNMJCOBO_00046 5.87e-86 - - - S - - - SnoaL-like domain
HNMJCOBO_00047 4.01e-190 - - - - - - - -
HNMJCOBO_00048 1.14e-149 yybJ - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HNMJCOBO_00049 2.34e-163 - - - S - - - Protein of unknown function (DUF2705)
HNMJCOBO_00050 5.36e-157 - - - - - - - -
HNMJCOBO_00051 3.78e-169 - - - - - - - -
HNMJCOBO_00052 1.61e-102 yybN - - S - - - Protein of unknown function (DUF2712)
HNMJCOBO_00053 3.44e-22 - - - - - - - -
HNMJCOBO_00054 1.37e-307 yybO - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
HNMJCOBO_00056 3.67e-80 - - - - - - - -
HNMJCOBO_00057 6.65e-208 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
HNMJCOBO_00058 1.3e-87 yybR - - K - - - Transcriptional regulator
HNMJCOBO_00059 6.83e-109 cotF - - M ko:K06329 - ko00000 Spore coat protein
HNMJCOBO_00061 1.5e-204 yybS - - S - - - membrane
HNMJCOBO_00062 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
HNMJCOBO_00063 2.74e-96 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
HNMJCOBO_00064 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HNMJCOBO_00065 9.87e-282 yycB - - P ko:K03449 - ko00000,ko02000 COG2807 Cyanate permease
HNMJCOBO_00066 1.89e-22 yycC - - K - - - YycC-like protein
HNMJCOBO_00068 3.48e-40 yycD - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
HNMJCOBO_00069 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
HNMJCOBO_00070 8.08e-100 yycE - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HNMJCOBO_00071 1.29e-314 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HNMJCOBO_00076 1.45e-172 yycF - - T ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HNMJCOBO_00077 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HNMJCOBO_00078 0.0 yycH - - S - - - protein conserved in bacteria
HNMJCOBO_00079 2.83e-199 yycI - - S - - - protein conserved in bacteria
HNMJCOBO_00080 1.9e-189 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
HNMJCOBO_00081 1.56e-277 yyxA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HNMJCOBO_00082 4.97e-44 - - - S - - - Peptidase propeptide and YPEB domain
HNMJCOBO_00083 1.88e-97 - - - S - - - Peptidase propeptide and YPEB domain
HNMJCOBO_00084 2.36e-122 - - - K ko:K02483 - ko00000,ko02022 PFAM response regulator receiver
HNMJCOBO_00085 2.26e-215 - 2.7.13.3 - T ko:K02484 - ko00000,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
HNMJCOBO_00086 0.0 rocR - - KT ko:K06714 - ko00000,ko03000 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
HNMJCOBO_00088 4.11e-294 rocD 2.6.1.13 - E ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko01007 Catalyzes the interconversion of ornithine to glutamate semialdehyde
HNMJCOBO_00089 0.0 rocE - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
HNMJCOBO_00090 3.22e-213 rocF 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
HNMJCOBO_00092 3.03e-239 - - - S - - - aspartate phosphatase
HNMJCOBO_00093 9.06e-112 yycN - - K - - - Acetyltransferase
HNMJCOBO_00094 2.78e-168 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HNMJCOBO_00095 1.02e-259 yycP - - - - - - -
HNMJCOBO_00096 4.53e-41 yycQ - - S - - - Protein of unknown function (DUF2651)
HNMJCOBO_00098 1.81e-297 yycR 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HNMJCOBO_00099 1.25e-93 - - - - - - - -
HNMJCOBO_00101 1.23e-106 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HNMJCOBO_00102 0.0 - - - S - - - Calcineurin-like phosphoesterase
HNMJCOBO_00103 7.17e-86 - - - - - - - -
HNMJCOBO_00104 0.0 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2326)
HNMJCOBO_00105 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Firmicute fructose-1,6-bisphosphatase
HNMJCOBO_00106 1.7e-142 - - - P ko:K16917 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HNMJCOBO_00107 4.04e-154 - - - S ko:K16916 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
HNMJCOBO_00108 3.99e-22 - - - - - - - -
HNMJCOBO_00109 2.38e-160 yydK - - K ko:K03489 - ko00000,ko03000 Transcriptional regulator
HNMJCOBO_00110 6.69e-47 - 2.7.1.199 - G ko:K02777,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system
HNMJCOBO_00111 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HNMJCOBO_00112 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 Alkyl hydroperoxide reductase
HNMJCOBO_00113 9.33e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Alkyl hydroperoxide reductase
HNMJCOBO_00114 0.0 gntZ 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HNMJCOBO_00115 5.87e-295 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
HNMJCOBO_00116 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
HNMJCOBO_00117 3.63e-163 gntR - - K ko:K11476 - ko00000,ko03000 transcriptional
HNMJCOBO_00118 6.98e-265 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
HNMJCOBO_00119 3.62e-245 - - - GM ko:K19426 - ko00000,ko01000 Polysaccharide pyruvyl transferase
HNMJCOBO_00120 8.56e-151 yxaC - - M - - - effector of murein hydrolase
HNMJCOBO_00121 2.53e-78 - - - S ko:K06518 - ko00000,ko02000 LrgA family
HNMJCOBO_00122 6.83e-94 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
HNMJCOBO_00123 5.23e-256 yxnA - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HNMJCOBO_00124 2.75e-130 yxaF - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
HNMJCOBO_00125 1.55e-252 - 1.13.11.24 - S ko:K07155 - ko00000,ko01000 AraC-like ligand binding domain
HNMJCOBO_00126 2.88e-290 - - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
HNMJCOBO_00127 2.83e-99 yxaI - - S - - - membrane protein domain
HNMJCOBO_00128 1.43e-85 - - - S - - - Family of unknown function (DUF5391)
HNMJCOBO_00129 2.63e-137 yxaL - - S - - - PQQ-like domain
HNMJCOBO_00130 1.8e-271 yxaM - - U - - - MFS_1 like family
HNMJCOBO_00131 0.0 - 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
HNMJCOBO_00132 8.99e-114 yxnB - - - - - - -
HNMJCOBO_00133 3.65e-59 - - - S - - - Coenzyme PQQ synthesis protein D (PqqD)
HNMJCOBO_00134 1.29e-177 yxbB - - Q - - - Met-10+ like-protein
HNMJCOBO_00135 1.16e-239 - - - S - - - A domain family that is part of the cupin metalloenzyme superfamily.
HNMJCOBO_00136 6.59e-111 yxbD 3.2.2.20 - K ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Acetyltransferase (GNAT) domain
HNMJCOBO_00137 1.21e-315 aldX 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
HNMJCOBO_00138 3.66e-275 yxbF - - K - - - Bacterial regulatory proteins, tetR family
HNMJCOBO_00139 4.33e-195 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
HNMJCOBO_00141 0.0 htpG - - O ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Molecular chaperone. Has ATPase activity
HNMJCOBO_00142 1.77e-314 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HNMJCOBO_00143 2.13e-64 yxcD - - S - - - Protein of unknown function (DUF2653)
HNMJCOBO_00145 3.52e-224 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
HNMJCOBO_00146 1.56e-177 iolR - - K ko:K06608,ko:K11534 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
HNMJCOBO_00147 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HNMJCOBO_00148 1.15e-198 iolB 5.3.1.30 - G ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
HNMJCOBO_00149 1.75e-227 iolC 2.7.1.92 - G ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
HNMJCOBO_00150 0.0 iolD 3.7.1.22 - E ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
HNMJCOBO_00151 4.27e-223 iolE 4.2.1.44 - G ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
HNMJCOBO_00152 1.46e-298 iolF - - EGP ko:K06610 - ko00000,ko02000 Major facilitator superfamily
HNMJCOBO_00153 8.95e-251 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
HNMJCOBO_00154 1.08e-212 iolH - - G ko:K06605 - ko00000 Xylose isomerase-like TIM barrel
HNMJCOBO_00155 5.39e-187 iolI 5.3.99.11 - G ko:K06606 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
HNMJCOBO_00156 2.43e-205 fbaA 4.1.2.13, 4.1.2.29 - F ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
HNMJCOBO_00157 2.8e-160 yxdJ - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HNMJCOBO_00158 4e-233 yxdK 2.7.13.3 - T ko:K11633 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HNMJCOBO_00159 9.39e-182 yxdL - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HNMJCOBO_00160 0.0 yxdM - - V ko:K11636 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
HNMJCOBO_00161 5.95e-77 yxeA - - S - - - Protein of unknown function (DUF1093)
HNMJCOBO_00162 9.01e-228 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HNMJCOBO_00163 6.79e-91 - - - - - - - -
HNMJCOBO_00164 8.77e-11 yxeD - - - - - - -
HNMJCOBO_00165 7.32e-42 yxeE - - - - - - -
HNMJCOBO_00168 4.49e-191 yxeH - - S - - - hydrolases of the HAD superfamily
HNMJCOBO_00169 6.41e-236 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
HNMJCOBO_00170 0.0 yxeK - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HNMJCOBO_00171 6.27e-121 yxeL - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HNMJCOBO_00172 4.3e-186 yxeM - - M ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
HNMJCOBO_00173 1.81e-149 yxeN - - P ko:K10009,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
HNMJCOBO_00174 3.94e-170 yxeO - - P ko:K16960,ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HNMJCOBO_00175 2.37e-271 yxeP - - E ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
HNMJCOBO_00176 1.87e-316 yxeQ - - S - - - MmgE/PrpD family
HNMJCOBO_00177 4.86e-259 eutH - - E ko:K04023 - ko00000 Ethanolamine utilisation protein, EutH
HNMJCOBO_00178 9.11e-198 - - - S - - - Domain of Unknown Function (DUF1206)
HNMJCOBO_00179 4.26e-222 deoR - - K ko:K05346 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HNMJCOBO_00180 1.44e-150 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HNMJCOBO_00181 1.92e-263 nupC - - F ko:K11535 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HNMJCOBO_00182 4.9e-300 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
HNMJCOBO_00183 0.0 ybgF - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
HNMJCOBO_00184 4.85e-231 hutG 3.5.3.8 - E ko:K01479 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
HNMJCOBO_00185 2.44e-303 hutI 3.5.2.7 - Q ko:K01468 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Imidazolone-5-propionate hydrolase
HNMJCOBO_00186 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HNMJCOBO_00187 0.0 hutH 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Histidine ammonia-lyase
HNMJCOBO_00188 7.02e-103 hutP - - K ko:K09683 - ko00000,ko03000 Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
HNMJCOBO_00189 0.0 yxiA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
HNMJCOBO_00190 1.88e-37 - - - S - - - Domain of unknown function (DUF5082)
HNMJCOBO_00191 2.3e-53 yxiC - - S - - - Family of unknown function (DUF5344)
HNMJCOBO_00192 0.0 - - - S ko:K21493 - ko00000,ko01000,ko02048 nuclease activity
HNMJCOBO_00193 9.25e-103 - - - S ko:K21494 - ko00000,ko02048 SMI1 / KNR4 family
HNMJCOBO_00194 1.33e-67 - - - - - - - -
HNMJCOBO_00195 0.0 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HNMJCOBO_00196 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HNMJCOBO_00197 8.5e-95 yxiE - - T - - - Belongs to the universal stress protein A family
HNMJCOBO_00198 1.17e-216 yxxF - - EG - - - EamA-like transporter family
HNMJCOBO_00199 0.0 wapA - - M - - - COG3209 Rhs family protein
HNMJCOBO_00200 1.09e-94 yxxG - - - - - - -
HNMJCOBO_00201 3.69e-111 - - - - - - - -
HNMJCOBO_00202 1.12e-82 - - - - - - - -
HNMJCOBO_00203 8.76e-99 yxiG - - - - - - -
HNMJCOBO_00204 1.2e-57 - - - - - - - -
HNMJCOBO_00205 6.22e-107 - - - - - - - -
HNMJCOBO_00206 1.74e-121 yxiI - - S - - - Protein of unknown function (DUF2716)
HNMJCOBO_00207 1.12e-64 yxiJ - - S - - - YxiJ-like protein
HNMJCOBO_00210 3.28e-279 - - - E - - - GDSL-like Lipase/Acylhydrolase
HNMJCOBO_00211 0.0 dbpA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
HNMJCOBO_00212 6.57e-293 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 COG2270 Permeases of the major facilitator superfamily
HNMJCOBO_00213 5.09e-141 - - - - - - - -
HNMJCOBO_00214 5.66e-193 licT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
HNMJCOBO_00215 3.06e-184 bglS - - M - - - licheninase activity
HNMJCOBO_00216 2e-284 citH - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
HNMJCOBO_00217 0.0 katE 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
HNMJCOBO_00218 9.65e-65 yxiS - - - - - - -
HNMJCOBO_00219 2.96e-29 - - - T - - - Domain of unknown function (DUF4163)
HNMJCOBO_00220 2.1e-269 nupG - - F ko:K16323 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HNMJCOBO_00221 4.55e-206 yxjB 2.1.1.187 - Q ko:K00563 - ko00000,ko01000,ko03009 Methyltransferase domain
HNMJCOBO_00222 0.0 yxjC - - EG - - - COG2610 H gluconate symporter and related permeases
HNMJCOBO_00223 1.56e-166 scoA 2.8.3.5 - I ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HNMJCOBO_00224 5.91e-151 scoB 2.8.3.5 - I ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HNMJCOBO_00225 5.83e-176 yxjF 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
HNMJCOBO_00226 1.09e-275 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
HNMJCOBO_00227 3.02e-277 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
HNMJCOBO_00228 4.78e-110 yxjI - - S - - - LURP-one-related
HNMJCOBO_00231 7.76e-299 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
HNMJCOBO_00232 1.23e-144 - - - K ko:K02479 - ko00000,ko02022 helix_turn_helix, Lux Regulon
HNMJCOBO_00233 1.37e-258 - - - T - - - Signal transduction histidine kinase
HNMJCOBO_00234 1.62e-101 - - - S - - - Protein of unknown function (DUF1453)
HNMJCOBO_00235 5.81e-249 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
HNMJCOBO_00236 1.66e-98 yxkC - - S - - - Domain of unknown function (DUF4352)
HNMJCOBO_00237 2.29e-188 yxkD - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
HNMJCOBO_00238 0.0 aldY 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HNMJCOBO_00239 1.12e-209 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
HNMJCOBO_00240 3.44e-261 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HNMJCOBO_00241 3.56e-197 yxkH - - G - - - Polysaccharide deacetylase
HNMJCOBO_00243 0.0 - - - O - - - Peptidase family M48
HNMJCOBO_00244 3.97e-310 cimH - - C - - - COG3493 Na citrate symporter
HNMJCOBO_00245 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
HNMJCOBO_00246 1.16e-243 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase, subunit II
HNMJCOBO_00247 0.0 cydC - - V ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding
HNMJCOBO_00248 0.0 cydD - - V ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding protein
HNMJCOBO_00249 2.01e-206 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HNMJCOBO_00250 0.0 yxlA - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
HNMJCOBO_00251 9.06e-125 sigY - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HNMJCOBO_00252 4.05e-64 yxlC - - S - - - Family of unknown function (DUF5345)
HNMJCOBO_00253 1.75e-43 - - - - - - - -
HNMJCOBO_00254 2.17e-39 yxlE - - S - - - Phospholipase_D-nuclease N-terminal
HNMJCOBO_00255 2.09e-213 yxlF - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HNMJCOBO_00256 3.96e-179 yxlG - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HNMJCOBO_00257 3.02e-275 yxlH - - EGP - - - Major Facilitator Superfamily
HNMJCOBO_00258 0.0 katX 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
HNMJCOBO_00259 3.23e-145 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
HNMJCOBO_00260 8.94e-28 yxzF - - - - - - -
HNMJCOBO_00261 0.0 licR - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
HNMJCOBO_00262 1.89e-67 licB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 transporter subunit IIB
HNMJCOBO_00263 0.0 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HNMJCOBO_00264 1.58e-50 licA 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HNMJCOBO_00265 0.0 licH 3.2.1.86 GT4 G ko:K01222 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HNMJCOBO_00266 1.07e-263 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
HNMJCOBO_00267 2.91e-178 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
HNMJCOBO_00268 4.09e-294 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HNMJCOBO_00269 6.83e-50 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HNMJCOBO_00270 1.14e-297 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 membrane protein involved in D-alanine export
HNMJCOBO_00271 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HNMJCOBO_00272 5.1e-213 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
HNMJCOBO_00273 2.52e-149 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 protein conserved in bacteria
HNMJCOBO_00274 3.96e-165 - - - EGP - - - Permeases of the major facilitator superfamily
HNMJCOBO_00275 5.58e-64 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
HNMJCOBO_00276 1.33e-116 - - - K - - - Helix-turn-helix XRE-family like proteins
HNMJCOBO_00277 0.0 ywaD 3.4.11.10, 3.4.11.6 - S ko:K19701 - ko00000,ko01000,ko01002 PA domain
HNMJCOBO_00278 1.75e-294 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HNMJCOBO_00279 1.25e-114 ywaE - - K - - - Transcriptional regulator
HNMJCOBO_00280 1.17e-156 ywaF - - S - - - Integral membrane protein
HNMJCOBO_00281 4.41e-215 gspA - - M - - - General stress
HNMJCOBO_00282 1.38e-190 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
HNMJCOBO_00283 1.45e-312 sacX 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HNMJCOBO_00284 0.0 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
HNMJCOBO_00285 6.37e-313 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HNMJCOBO_00286 1.13e-150 ywbB - - S - - - Protein of unknown function (DUF2711)
HNMJCOBO_00287 4.01e-87 ywbC 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 glyoxalase
HNMJCOBO_00288 2.7e-278 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
HNMJCOBO_00289 6.33e-38 ywbE - - S - - - Uncharacterized conserved protein (DUF2196)
HNMJCOBO_00290 4.14e-277 ywbF - - EGP ko:K05820 - ko00000,ko02000 Nucleoside H+ symporter
HNMJCOBO_00291 1.21e-143 ywbG - - M - - - effector of murein hydrolase
HNMJCOBO_00292 1.1e-76 ywbH - - S ko:K06518 - ko00000,ko02000 Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
HNMJCOBO_00293 1.56e-202 ywbI - - K - - - Transcriptional regulator
HNMJCOBO_00294 1.27e-182 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HNMJCOBO_00295 1.74e-146 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HNMJCOBO_00296 0.0 - - - P ko:K07243 - ko00000,ko02000 COG0672 High-affinity Fe2 Pb2 permease
HNMJCOBO_00297 4.18e-247 ycdO - - P ko:K07224 - ko00000,ko02000 periplasmic lipoprotein involved in iron transport
HNMJCOBO_00298 4.4e-308 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Dyp-type peroxidase family protein
HNMJCOBO_00299 1.09e-142 ywbO - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
HNMJCOBO_00300 0.0 ywcA - - S ko:K14393 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HNMJCOBO_00301 4.29e-64 ywcB - - S - - - Protein of unknown function, DUF485
HNMJCOBO_00303 3.42e-158 ywcC - - K - - - transcriptional regulator
HNMJCOBO_00304 3.33e-77 gtcA - - S - - - GtrA-like protein
HNMJCOBO_00305 5.12e-287 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HNMJCOBO_00306 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
HNMJCOBO_00307 5.11e-49 ydaS - - S - - - membrane
HNMJCOBO_00308 6.94e-226 qoxA 1.10.3.12 - C ko:K02826 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
HNMJCOBO_00309 0.0 qoxB 1.10.3.12 - C ko:K02827 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HNMJCOBO_00310 1.2e-144 qoxC 1.10.3.12 - C ko:K02828 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
HNMJCOBO_00311 1.12e-83 qoxD 1.10.3.12 - C ko:K02829 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
HNMJCOBO_00312 6.61e-52 ywcE - - S - - - Required for proper spore morphogenesis. Important for spore germination
HNMJCOBO_00313 1.29e-260 - - - S - - - Acetyltransferase
HNMJCOBO_00314 8.89e-269 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
HNMJCOBO_00315 9.4e-178 nfrA1 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Oxidoreductase
HNMJCOBO_00316 3.44e-238 ywcH - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HNMJCOBO_00317 0.0 prtS 3.4.21.110, 3.4.21.96 - O ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
HNMJCOBO_00319 3.03e-192 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
HNMJCOBO_00320 3.4e-179 - - - P ko:K02598 - ko00000,ko02000 Formate/nitrite transporter
HNMJCOBO_00321 0.0 sacP 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HNMJCOBO_00322 0.0 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
HNMJCOBO_00323 6.19e-39 ywdA - - - - - - -
HNMJCOBO_00324 2.21e-187 pdxK 2.7.1.35, 2.7.1.49, 2.7.4.7 - H ko:K00868,ko:K00941 ko00730,ko00750,ko01100,map00730,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
HNMJCOBO_00325 7.92e-76 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator PadR-like family
HNMJCOBO_00326 2.77e-78 ywdD - - - - - - -
HNMJCOBO_00327 9.58e-54 ywdD - - - - - - -
HNMJCOBO_00329 1.34e-191 ywdF - - S - - - Glycosyltransferase like family 2
HNMJCOBO_00330 9.47e-166 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HNMJCOBO_00331 1.3e-87 ywdH 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
HNMJCOBO_00332 5.52e-209 ywdH 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
HNMJCOBO_00333 2.18e-63 ywdI - - S - - - Family of unknown function (DUF5327)
HNMJCOBO_00334 1.86e-303 ywdJ - - F - - - Xanthine uracil
HNMJCOBO_00335 1.59e-78 ywdK - - S - - - small membrane protein
HNMJCOBO_00336 3.62e-112 gerQ - - S ko:K06305 - ko00000 Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
HNMJCOBO_00337 9.44e-186 spsA - - M - - - Spore Coat
HNMJCOBO_00338 0.0 spsB - - M - - - Capsule polysaccharide biosynthesis protein
HNMJCOBO_00339 5.29e-284 spsC 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
HNMJCOBO_00340 3.47e-209 spsD 2.3.1.210 - K ko:K16704 - ko00000,ko01000 Spore Coat
HNMJCOBO_00341 1.95e-271 pseI 2.5.1.56, 2.5.1.97 - M ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 acid synthase
HNMJCOBO_00342 5.42e-168 spsF - - M ko:K07257 - ko00000 Spore Coat
HNMJCOBO_00343 5.73e-240 spsG - - M - - - Spore Coat
HNMJCOBO_00344 7.45e-178 spsI 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HNMJCOBO_00345 3.7e-233 spsJ 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HNMJCOBO_00346 4.72e-204 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HNMJCOBO_00347 3.73e-113 spsL 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Spore Coat
HNMJCOBO_00348 3.7e-101 - - - - - - - -
HNMJCOBO_00349 2.11e-310 rocG 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
HNMJCOBO_00350 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
HNMJCOBO_00351 0.0 rocB - - E - - - arginine degradation protein
HNMJCOBO_00352 0.0 rocC - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
HNMJCOBO_00353 6.3e-274 ywfA - - EGP - - - -transporter
HNMJCOBO_00354 5.11e-146 bacA 4.1.1.100 - E ko:K19546 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
HNMJCOBO_00355 1.24e-175 bacB 5.3.3.19 - S ko:K19547 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
HNMJCOBO_00356 2.21e-178 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HNMJCOBO_00357 0.0 bacD 6.3.2.49 - F ko:K13037 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
HNMJCOBO_00358 1.31e-266 bacE - - EGP ko:K19552 - ko00000,ko02000 Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
HNMJCOBO_00359 1.89e-298 ywfG - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
HNMJCOBO_00360 1.67e-176 ywfH - - IQ ko:K19550 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Enoyl-(Acyl carrier protein) reductase
HNMJCOBO_00361 3.43e-187 ywfI - - C ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko01000 May function as heme-dependent peroxidase
HNMJCOBO_00362 1.67e-224 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 In Salmonella this enzyme is required for ethanolamine catabolism
HNMJCOBO_00363 3.73e-209 cysL - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
HNMJCOBO_00364 2.15e-199 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
HNMJCOBO_00365 3.7e-203 ywfM - - EG ko:K03298 - ko00000,ko02000 EamA-like transporter family
HNMJCOBO_00366 6.58e-146 rsfA_1 - - - ko:K06314 - ko00000,ko03000 -
HNMJCOBO_00367 8.55e-49 ywzC - - S - - - Belongs to the UPF0741 family
HNMJCOBO_00368 0.0 ywfO - - S ko:K06885 - ko00000 COG1078 HD superfamily phosphohydrolases
HNMJCOBO_00369 1.47e-115 ywgA - - - ko:K09388 - ko00000 -
HNMJCOBO_00370 1.23e-100 yffB - - K - - - Transcriptional regulator
HNMJCOBO_00371 4.03e-302 mmr - - U ko:K08166 - ko00000,ko02000 Major Facilitator Superfamily
HNMJCOBO_00373 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HNMJCOBO_00374 1.76e-94 ywhA - - K - - - Transcriptional regulator
HNMJCOBO_00375 1.43e-35 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 4-oxalocrotonate tautomerase
HNMJCOBO_00376 3.29e-154 ywhC - - S - - - Peptidase family M50
HNMJCOBO_00377 7.83e-123 ywhD - - S - - - YwhD family
HNMJCOBO_00378 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M ko:K21464 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
HNMJCOBO_00379 1.93e-204 speE 2.5.1.16 - E ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HNMJCOBO_00380 6.02e-215 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
HNMJCOBO_00381 2.17e-37 - - - S - - - Aminoacyl-tRNA editing domain
HNMJCOBO_00383 2.32e-99 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
HNMJCOBO_00384 1e-269 ywhK - - CO - - - amine dehydrogenase activity
HNMJCOBO_00385 0.0 ywhL - - CO - - - amine dehydrogenase activity
HNMJCOBO_00387 7.71e-314 - - - L - - - Peptidase, M16
HNMJCOBO_00388 1.34e-273 - 2.7.1.26, 2.7.7.2 - L ko:K07263,ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01002 Peptidase, M16
HNMJCOBO_00389 6.61e-295 mgtA 3.6.3.2 - P ko:K01531,ko:K16905 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPase, P-type transporting, HAD superfamily, subfamily IC
HNMJCOBO_00390 1.5e-169 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HNMJCOBO_00392 0.0 - - - C ko:K22227 - ko00000 Fe-S oxidoreductases
HNMJCOBO_00393 3.71e-12 - - - S - - - Bacteriocin subtilosin A
HNMJCOBO_00394 4.64e-96 ywiB - - S - - - protein conserved in bacteria
HNMJCOBO_00395 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
HNMJCOBO_00396 4.81e-274 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
HNMJCOBO_00397 2.3e-168 fnr - - K - - - helix_turn_helix, cAMP Regulatory protein
HNMJCOBO_00398 1.02e-176 ywiC - - S - - - YwiC-like protein
HNMJCOBO_00399 8.67e-111 arfM - - T ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 cyclic nucleotide binding
HNMJCOBO_00400 0.0 narG 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HNMJCOBO_00401 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase, beta
HNMJCOBO_00402 1.95e-122 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase
HNMJCOBO_00403 4.16e-159 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase (gamma
HNMJCOBO_00404 0.0 ywiE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HNMJCOBO_00405 0.0 ywjA - - V ko:K06147 - ko00000,ko02000 ABC transporter
HNMJCOBO_00406 1.51e-121 ywjB - - H - - - RibD C-terminal domain
HNMJCOBO_00407 1.32e-57 ywjC - - - - - - -
HNMJCOBO_00408 8.09e-235 uvsE - - L ko:K13281 - ko00000,ko01000 Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
HNMJCOBO_00409 1.93e-286 clsB - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the phospholipase D family. Cardiolipin synthase subfamily
HNMJCOBO_00410 0.0 ywjF - - C - - - COG0247 Fe-S oxidoreductase
HNMJCOBO_00411 2.1e-269 acdA - - I - - - acyl-CoA dehydrogenase
HNMJCOBO_00412 1.03e-82 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HNMJCOBO_00413 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HNMJCOBO_00414 3.31e-120 ywjG - - S - - - Domain of unknown function (DUF2529)
HNMJCOBO_00415 1.07e-81 spo0F - - T ko:K02490 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG0784 FOG CheY-like receiver
HNMJCOBO_00416 7.82e-204 fbaA 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Aldolase
HNMJCOBO_00417 5.69e-147 tal 2.2.1.2 - G ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HNMJCOBO_00418 2.26e-303 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HNMJCOBO_00419 3.51e-225 glpX 3.1.3.11 - G ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 fructose-1,6-bisphosphatase
HNMJCOBO_00420 5.53e-303 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HNMJCOBO_00421 7e-45 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
HNMJCOBO_00422 8.53e-136 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
HNMJCOBO_00423 0.0 ykwA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
HNMJCOBO_00424 3.24e-204 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
HNMJCOBO_00425 6.26e-119 racA - - K ko:K11686 - ko00000,ko03036 Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
HNMJCOBO_00426 1.19e-89 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HNMJCOBO_00427 9.95e-245 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HNMJCOBO_00428 5.96e-205 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HNMJCOBO_00430 1.67e-74 ywlA - - S - - - Uncharacterised protein family (UPF0715)
HNMJCOBO_00431 1.14e-152 spoIIR - - S ko:K06387 - ko00000 stage II sporulation protein R
HNMJCOBO_00432 1.79e-100 ywlB - - E - - - Belongs to the acetyltransferase family. ArgA subfamily
HNMJCOBO_00433 4.44e-252 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HNMJCOBO_00434 4.56e-117 mntP - - P - - - Probably functions as a manganese efflux pump
HNMJCOBO_00435 5.75e-103 ywlE 3.1.3.48, 3.9.1.2 - T ko:K01104,ko:K20201 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HNMJCOBO_00436 2.35e-106 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase
HNMJCOBO_00437 2.49e-123 ywlG - - S - - - Belongs to the UPF0340 family
HNMJCOBO_00438 4.36e-303 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HNMJCOBO_00439 5.5e-148 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HNMJCOBO_00440 1.91e-81 atpI - - S ko:K02116 - ko00000,ko00194 ATP synthase
HNMJCOBO_00441 6.06e-167 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
HNMJCOBO_00442 3.01e-36 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HNMJCOBO_00443 2.62e-79 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HNMJCOBO_00444 2.89e-118 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HNMJCOBO_00445 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HNMJCOBO_00446 4.46e-195 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HNMJCOBO_00447 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HNMJCOBO_00448 1.04e-76 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
HNMJCOBO_00449 6.12e-115 ywmA - - - - - - -
HNMJCOBO_00450 4.54e-45 ywzB - - S - - - membrane
HNMJCOBO_00451 2.39e-174 ywmB - - S - - - TATA-box binding
HNMJCOBO_00452 4.96e-306 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HNMJCOBO_00453 3.72e-238 spoIID - - D ko:K06381 - ko00000 Stage II sporulation protein D
HNMJCOBO_00454 1.89e-157 ywmC - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
HNMJCOBO_00455 1.02e-155 ywmD - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
HNMJCOBO_00457 2.22e-187 fdhD - - C ko:K02379 - ko00000 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HNMJCOBO_00458 2.65e-246 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HNMJCOBO_00459 1.25e-128 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
HNMJCOBO_00460 1.12e-109 ywmF - - S - - - Peptidase M50
HNMJCOBO_00461 1.11e-21 csbD - - K - - - CsbD-like
HNMJCOBO_00463 8.2e-68 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
HNMJCOBO_00464 1.12e-83 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
HNMJCOBO_00465 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
HNMJCOBO_00466 4.58e-85 ywnA - - K - - - Transcriptional regulator
HNMJCOBO_00467 1.29e-148 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
HNMJCOBO_00468 1.06e-78 ywnC - - S - - - Family of unknown function (DUF5362)
HNMJCOBO_00469 3.41e-184 mta - - K ko:K21743 - ko00000,ko03000 transcriptional
HNMJCOBO_00470 0.0 ywnE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HNMJCOBO_00471 7.07e-92 ywnF - - S - - - Family of unknown function (DUF5392)
HNMJCOBO_00472 3.28e-22 ywnC - - S - - - Family of unknown function (DUF5362)
HNMJCOBO_00473 1.55e-116 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 COG1247 Sortase and related acyltransferases
HNMJCOBO_00474 2.13e-175 spoIIQ - - M ko:K06386 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
HNMJCOBO_00475 1.63e-95 ywnJ - - S - - - VanZ like family
HNMJCOBO_00476 6.02e-135 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 COG0671 Membrane-associated phospholipid phosphatase
HNMJCOBO_00477 4.51e-77 nrgB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
HNMJCOBO_00478 1.6e-288 nrgA - - P ko:K03320 - ko00000,ko02000 Ammonium transporter
HNMJCOBO_00479 4.15e-100 - - - - - - - -
HNMJCOBO_00480 2.56e-134 yjgF - - Q - - - Isochorismatase family
HNMJCOBO_00481 8e-309 ywoD - - EGP - - - Major facilitator superfamily
HNMJCOBO_00482 0.0 - - - FH ko:K03457,ko:K10975 - ko00000,ko02000 COG1953 Cytosine uracil thiamine allantoin permeases
HNMJCOBO_00483 1.02e-312 ywoF - - P - - - Right handed beta helix region
HNMJCOBO_00484 1.37e-269 ywoG - - EGP - - - COG0477 Permeases of the major facilitator superfamily
HNMJCOBO_00485 8.45e-92 - - - K - - - COG1846 Transcriptional regulators
HNMJCOBO_00486 4.88e-59 spoIIID - - K ko:K06283 - ko00000,ko03000 Stage III sporulation protein D
HNMJCOBO_00487 1.75e-231 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein
HNMJCOBO_00488 6.18e-173 flhO - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
HNMJCOBO_00489 4.1e-182 flhP - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
HNMJCOBO_00490 5.45e-257 rapD - - S ko:K06362 - ko00000,ko01000 aspartate phosphatase
HNMJCOBO_00491 6.89e-107 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HNMJCOBO_00492 1.13e-79 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HNMJCOBO_00493 2.55e-197 ywpD - - T - - - Histidine kinase
HNMJCOBO_00494 4.63e-68 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
HNMJCOBO_00495 8.81e-89 ywpF - - S - - - YwpF-like protein
HNMJCOBO_00496 5.26e-88 ywpG - - - - - - -
HNMJCOBO_00497 1.04e-76 ssbB - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
HNMJCOBO_00498 4.82e-180 glcR - - K ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
HNMJCOBO_00499 5.28e-202 ywpJ 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
HNMJCOBO_00500 0.0 ywqA - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
HNMJCOBO_00501 0.0 ywqB - - S - - - SWIM zinc finger
HNMJCOBO_00502 3.6e-25 - - - - - - - -
HNMJCOBO_00503 5.33e-163 ywqC - - M ko:K19420 - ko00000 biosynthesis protein
HNMJCOBO_00504 4.51e-156 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
HNMJCOBO_00505 3.16e-183 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 COG4464 Capsular polysaccharide biosynthesis protein
HNMJCOBO_00506 9.82e-315 ywqF 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HNMJCOBO_00507 7.24e-197 ywqG - - S - - - Domain of unknown function (DUF1963)
HNMJCOBO_00509 8.84e-52 ywqI - - S - - - Family of unknown function (DUF5344)
HNMJCOBO_00510 1.44e-302 ywqJ - - S - - - Pre-toxin TG
HNMJCOBO_00512 2.92e-148 nfi 3.1.21.7 - L ko:K05982 - ko00000,ko01000,ko03400 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
HNMJCOBO_00513 2.34e-209 - - - K - - - Transcriptional regulator
HNMJCOBO_00514 5.03e-128 ywqN - - S - - - NAD(P)H-dependent
HNMJCOBO_00516 3.66e-115 ywrA - - P ko:K07240 - ko00000,ko02000 COG2059 Chromate transport protein ChrA
HNMJCOBO_00517 5.52e-133 ywrB - - P ko:K07240 - ko00000,ko02000 Chromate transporter
HNMJCOBO_00518 4.83e-108 ywrC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
HNMJCOBO_00519 0.0 ywrD 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
HNMJCOBO_00520 2.78e-71 - - - S - - - Domain of unknown function (DUF4181)
HNMJCOBO_00521 5.08e-142 ywrF - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HNMJCOBO_00522 1.81e-16 - - - - - - - -
HNMJCOBO_00523 4.57e-269 cotH - - M ko:K06330 - ko00000 Spore Coat
HNMJCOBO_00524 2.75e-187 cotB - - - ko:K06325 - ko00000 -
HNMJCOBO_00525 4.33e-162 ywrJ - - - - - - -
HNMJCOBO_00526 6.85e-281 ywrK - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HNMJCOBO_00527 3.36e-218 alsR - - K - - - LysR substrate binding domain
HNMJCOBO_00528 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
HNMJCOBO_00529 1.51e-186 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
HNMJCOBO_00530 8.76e-126 ywrO - - S - - - NADPH-quinone reductase (modulator of drug activity B)
HNMJCOBO_00531 3.75e-63 ywsA - - S - - - Protein of unknown function (DUF3892)
HNMJCOBO_00532 2.49e-122 batE - - T - - - Sh3 type 3 domain protein
HNMJCOBO_00533 1.34e-205 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 COG1879 ABC-type sugar transport system, periplasmic component
HNMJCOBO_00534 3.35e-203 rbsC - - G ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HNMJCOBO_00535 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
HNMJCOBO_00536 3.24e-84 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HNMJCOBO_00537 2.62e-206 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HNMJCOBO_00538 2.3e-228 rbsR - - K ko:K02529 - ko00000,ko03000 transcriptional
HNMJCOBO_00539 1.46e-283 capB - - M ko:K01932 - ko00000,ko01000 COG0769 UDP-N-acetylmuramyl tripeptide synthase
HNMJCOBO_00540 8.44e-91 capC - - S ko:K22116 - ko00000 biosynthesis protein
HNMJCOBO_00541 1.33e-277 capA - - M ko:K07282 - ko00000 enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
HNMJCOBO_00542 1.33e-28 ywtC - - - - - - -
HNMJCOBO_00543 4.58e-303 pgdS - - M - - - COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HNMJCOBO_00544 1.46e-204 ywtE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
HNMJCOBO_00545 1.48e-222 ywtF_2 - - K - - - Transcriptional regulator
HNMJCOBO_00546 3.71e-314 ywtG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HNMJCOBO_00547 4.25e-271 gerBC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination protein
HNMJCOBO_00548 9.74e-254 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
HNMJCOBO_00549 0.0 gerBA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
HNMJCOBO_00550 1.16e-241 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
HNMJCOBO_00551 0.0 lytD 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HNMJCOBO_00552 0.0 - - - - - - - -
HNMJCOBO_00553 3.8e-273 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HNMJCOBO_00554 1.9e-185 tagA 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HNMJCOBO_00555 3.82e-91 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase
HNMJCOBO_00556 0.0 tagE 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferase 1 domain A
HNMJCOBO_00557 0.0 tagF 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HNMJCOBO_00558 2.06e-194 tagG - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
HNMJCOBO_00559 0.0 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HNMJCOBO_00560 2.13e-127 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
HNMJCOBO_00561 5.43e-05 - 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase-like
HNMJCOBO_00562 0.0 - - - M - - - Glycosyltransferase like family 2
HNMJCOBO_00563 0.0 - - - M - - - CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HNMJCOBO_00564 1.78e-208 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
HNMJCOBO_00565 6.61e-278 mnaA 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HNMJCOBO_00566 2.77e-219 lytR - - K - - - May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
HNMJCOBO_00567 3.26e-50 - - - - - - - -
HNMJCOBO_00568 0.0 lytB - - D - - - Stage II sporulation protein
HNMJCOBO_00569 0.0 lytC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
HNMJCOBO_00570 1.49e-143 tuaA - - M - - - COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HNMJCOBO_00571 2.58e-316 tuaB - - S ko:K03328,ko:K16694,ko:K16695 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HNMJCOBO_00572 5.68e-279 tuaC - GT4 GM ko:K16697 - ko00000,ko01000,ko01003 Teichuronic acid
HNMJCOBO_00573 0.0 tuaD 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HNMJCOBO_00574 0.0 tuaE - - M ko:K16705 - ko00000 Teichuronic acid biosynthesis protein
HNMJCOBO_00575 1.36e-145 tuaF - - M ko:K16706 - ko00000 protein involved in exopolysaccharide biosynthesis
HNMJCOBO_00576 8.42e-187 tuaG - GT2 M ko:K16698 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
HNMJCOBO_00577 3.3e-303 tuaH - - M ko:K16699 - ko00000,ko01000,ko01003 Teichuronic acid biosynthesis glycosyltransferase tuaH
HNMJCOBO_00578 2.1e-231 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
HNMJCOBO_00579 3.99e-225 yvhJ - - K - - - Transcriptional regulator
HNMJCOBO_00580 2.41e-155 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 Domain of unknown function (DUF1949)
HNMJCOBO_00581 2.94e-247 degS 2.7.13.3 - T ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
HNMJCOBO_00582 7.16e-163 degU - - KT ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HNMJCOBO_00583 2.15e-199 degV - - S - - - protein conserved in bacteria
HNMJCOBO_00584 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HNMJCOBO_00585 1.26e-61 comFB - - S ko:K02241 - ko00000,ko00002,ko02044 Late competence development protein ComFB
HNMJCOBO_00586 9.99e-166 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Phosphoribosyl transferase domain
HNMJCOBO_00587 1.83e-96 yvyF - - S - - - flagellar protein
HNMJCOBO_00588 1.06e-53 flgM - - KNU ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 ko00000,ko00001,ko02035 Negative regulator of flagellin synthesis
HNMJCOBO_00589 3.5e-102 yvyG - - NOU - - - FlgN protein
HNMJCOBO_00590 0.0 flgK - - N ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 flagellar hook-associated protein
HNMJCOBO_00591 2.67e-197 flgL - - N ko:K02397 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the bacterial flagellin family
HNMJCOBO_00592 4.19e-93 yviE - - - - - - -
HNMJCOBO_00593 1.23e-96 fliW - - S ko:K13626 - ko00000,ko02035 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
HNMJCOBO_00594 2.58e-41 csrA - - T ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 ko00000,ko00001,ko03019 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HNMJCOBO_00595 8.01e-202 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HNMJCOBO_00596 1.1e-76 flaG - - N ko:K06603 - ko00000,ko02035 flagellar protein FlaG
HNMJCOBO_00597 0.0 fliD - - N ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HNMJCOBO_00598 5.15e-91 fliS - - N ko:K02422 ko02040,map02040 ko00000,ko00001,ko02035 flagellar protein FliS
HNMJCOBO_00599 8.69e-09 fliT - - S ko:K02423 ko02040,map02040 ko00000,ko00001,ko02035 bacterial-type flagellum organization
HNMJCOBO_00600 9.14e-88 - - - - - - - -
HNMJCOBO_00601 1.73e-132 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HNMJCOBO_00602 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HNMJCOBO_00603 2e-232 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HNMJCOBO_00604 6.5e-185 yvjA - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
HNMJCOBO_00605 3.23e-75 cccB - - C ko:K12263,ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
HNMJCOBO_00606 1.5e-159 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
HNMJCOBO_00607 5.45e-199 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HNMJCOBO_00608 0.0 ctpB 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
HNMJCOBO_00609 1.38e-73 swrA - - S - - - Swarming motility protein
HNMJCOBO_00610 3.86e-281 minJ - - O - - - COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HNMJCOBO_00611 5.47e-298 yvkA - - P - - - -transporter
HNMJCOBO_00612 1.43e-131 yvkB - - K - - - Transcriptional regulator
HNMJCOBO_00613 0.0 yvkC 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Phosphotransferase
HNMJCOBO_00614 2.54e-42 csbA - - S - - - protein conserved in bacteria
HNMJCOBO_00615 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HNMJCOBO_00616 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HNMJCOBO_00617 2.57e-104 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HNMJCOBO_00618 2.73e-46 yvkN - - - - - - -
HNMJCOBO_00619 8.09e-65 yvlA - - - - - - -
HNMJCOBO_00620 5.8e-221 yvlB - - S - - - Putative adhesin
HNMJCOBO_00621 1.5e-36 yvlC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
HNMJCOBO_00622 3.8e-66 yvlD - - S ko:K08972 - ko00000 Membrane
HNMJCOBO_00623 4.26e-272 yvmA - - EGP - - - Major Facilitator Superfamily
HNMJCOBO_00624 6.2e-114 yvmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
HNMJCOBO_00625 2.49e-177 yvmC 2.3.2.22 - S ko:K17485 - ko00000,ko01000 Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
HNMJCOBO_00626 1.61e-293 cypX 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
HNMJCOBO_00627 9.4e-110 yvnA - - K - - - helix_turn_helix multiple antibiotic resistance protein
HNMJCOBO_00628 0.0 yvnB - - Q - - - Calcineurin-like phosphoesterase
HNMJCOBO_00629 5.23e-172 yvoA - - K ko:K03710 - ko00000,ko03000 transcriptional
HNMJCOBO_00630 1.39e-171 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HNMJCOBO_00631 2.25e-284 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
HNMJCOBO_00632 4.22e-216 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HNMJCOBO_00633 3.18e-195 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HNMJCOBO_00634 3.19e-212 yvoD - - P - - - COG0370 Fe2 transport system protein B
HNMJCOBO_00635 4.51e-155 ppaX 3.6.1.1 - S ko:K06019 ko00190,map00190 ko00000,ko00001,ko01000 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
HNMJCOBO_00636 5.29e-121 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
HNMJCOBO_00637 5.68e-156 - 4.2.2.10, 4.2.2.2 - G ko:K19551 ko00040,map00040 ko00000,ko00001,ko01000 Pectate lyase
HNMJCOBO_00638 2.14e-179 yvpB - - NU - - - protein conserved in bacteria
HNMJCOBO_00639 2.07e-282 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HNMJCOBO_00640 9.09e-149 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HNMJCOBO_00641 1.19e-297 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HNMJCOBO_00642 4.96e-139 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
HNMJCOBO_00643 8.42e-149 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HNMJCOBO_00644 1.44e-170 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HNMJCOBO_00645 9.74e-177 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HNMJCOBO_00646 5.06e-144 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the PRA-CH family
HNMJCOBO_00647 2.39e-104 - - - - - - - -
HNMJCOBO_00648 7.49e-314 - - - - - - - -
HNMJCOBO_00650 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
HNMJCOBO_00651 0.0 yvcD - - S - - - COG0457 FOG TPR repeat
HNMJCOBO_00652 3.05e-190 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 protein conserved in bacteria
HNMJCOBO_00653 8.31e-226 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HNMJCOBO_00654 2.39e-117 yvcI 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HNMJCOBO_00655 2.09e-213 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
HNMJCOBO_00656 6.72e-227 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
HNMJCOBO_00657 3.63e-220 whiA - - K ko:K09762 - ko00000 May be required for sporulation
HNMJCOBO_00658 3.92e-50 crh - - G ko:K11184 - ko00000 Phosphocarrier protein Chr
HNMJCOBO_00659 5.24e-188 yvcN 2.3.1.118 - Q ko:K00675 - ko00000,ko01000 Belongs to the arylamine N-acetyltransferase family
HNMJCOBO_00660 1.37e-45 - - - - - - - -
HNMJCOBO_00661 4.67e-172 yvcP - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HNMJCOBO_00662 2.98e-246 yvcQ - - T - - - His Kinase A (phosphoacceptor) domain
HNMJCOBO_00663 4.46e-181 yxdL_2 - - V ko:K02003,ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HNMJCOBO_00664 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
HNMJCOBO_00665 1.15e-234 yvcT 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HNMJCOBO_00666 3.73e-137 yvdA 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
HNMJCOBO_00667 0.0 yvdB - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
HNMJCOBO_00668 7.84e-71 yvdC - - S - - - MazG nucleotide pyrophosphohydrolase domain
HNMJCOBO_00669 1.54e-136 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
HNMJCOBO_00670 1.32e-222 yvdE - - K - - - Transcriptional regulator
HNMJCOBO_00671 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, N-terminal ig-like domain
HNMJCOBO_00672 8.46e-302 mdxE - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
HNMJCOBO_00673 8.65e-311 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
HNMJCOBO_00674 6.56e-188 malD - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
HNMJCOBO_00675 1.34e-200 malA - - S - - - Protein of unknown function (DUF1189)
HNMJCOBO_00676 0.0 yvdK 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycoside hydrolase, family 65
HNMJCOBO_00677 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
HNMJCOBO_00678 4.77e-150 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
HNMJCOBO_00679 8.17e-135 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HNMJCOBO_00681 9.45e-234 - - - S - - - Patatin-like phospholipase
HNMJCOBO_00682 0.0 yvdP - - C - - - COG0277 FAD FMN-containing dehydrogenases
HNMJCOBO_00683 1.59e-121 yvdQ - - S - - - Protein of unknown function (DUF3231)
HNMJCOBO_00684 1.03e-66 yvdR - - P ko:K11741 - ko00000,ko02000 Small Multidrug Resistance protein
HNMJCOBO_00685 2.57e-67 yvdS - - P ko:K18924 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
HNMJCOBO_00686 4.76e-137 yvdT_1 - - K - - - Transcriptional regulator
HNMJCOBO_00687 0.0 ybeC - - E - - - amino acid
HNMJCOBO_00688 0.0 sacC3 3.2.1.65 GH32 G ko:K01212 ko00500,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
HNMJCOBO_00689 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 levansucrase activity
HNMJCOBO_00690 0.0 pbpE - - V - - - Beta-lactamase
HNMJCOBO_00691 1.51e-163 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
HNMJCOBO_00692 5.1e-64 - - - S - - - Protein of unknown function (DUF3237)
HNMJCOBO_00693 5.4e-120 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
HNMJCOBO_00695 0.0 pnbA - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
HNMJCOBO_00696 2.15e-99 - - - K ko:K19417 - ko00000,ko03000 transcriptional
HNMJCOBO_00697 2.78e-158 epsA - - M ko:K19420 - ko00000 biosynthesis protein
HNMJCOBO_00698 7.94e-150 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
HNMJCOBO_00699 0.0 capD - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
HNMJCOBO_00700 3.17e-281 epsD - GT4 M ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like
HNMJCOBO_00701 1.25e-201 epsE - GT2 M ko:K19423 - ko00000,ko01000,ko01003 COG0463 Glycosyltransferases involved in cell wall biogenesis
HNMJCOBO_00702 1.14e-274 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
HNMJCOBO_00703 1.03e-263 epsG - - S ko:K19419 - ko00000,ko02000 EpsG family
HNMJCOBO_00704 3.65e-250 epsH - GT2 S ko:K19425 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
HNMJCOBO_00705 5.09e-264 epsI - - GM ko:K19426 - ko00000,ko01000 pyruvyl transferase
HNMJCOBO_00706 4.44e-251 epsJ - GT2 S ko:K19427 - ko00000,ko01000 COG0463 Glycosyltransferases involved in cell wall biogenesis
HNMJCOBO_00707 0.0 epsK - - S ko:K19418 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HNMJCOBO_00708 1.65e-141 epsL - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HNMJCOBO_00709 6.53e-81 epsM - - GM ko:K19429 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
HNMJCOBO_00710 1.2e-284 epsN - - E ko:K19430 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
HNMJCOBO_00711 1.85e-241 epsO - - GM ko:K19431 - ko00000,ko01000 Exopolysaccharide biosynthesis protein
HNMJCOBO_00712 5.69e-44 yvfG - - S - - - YvfG protein
HNMJCOBO_00713 2.57e-308 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
HNMJCOBO_00714 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
HNMJCOBO_00715 6.85e-146 yvfI - - K ko:K05799 - ko00000,ko03000 COG2186 Transcriptional regulators
HNMJCOBO_00716 6.42e-237 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
HNMJCOBO_00717 3.4e-294 cycB - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
HNMJCOBO_00718 2.15e-300 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
HNMJCOBO_00719 3.82e-194 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
HNMJCOBO_00720 0.0 lacA 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 beta-galactosidase
HNMJCOBO_00721 0.0 ganB 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
HNMJCOBO_00722 1.14e-260 - 3.1.3.3 - T ko:K07315 - ko00000,ko01000,ko03021 response regulator
HNMJCOBO_00723 1.46e-200 rsbQ - - S ko:K19707 - ko00000,ko03021 Alpha/beta hydrolase family
HNMJCOBO_00724 6.37e-204 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
HNMJCOBO_00725 2.04e-170 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
HNMJCOBO_00726 3.48e-248 yvfT 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HNMJCOBO_00727 4.36e-136 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HNMJCOBO_00728 3.04e-173 lutA - - C ko:K18928 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HNMJCOBO_00729 0.0 lutB - - C ko:K18929 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
HNMJCOBO_00730 1.69e-171 lutC - - S ko:K00782 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HNMJCOBO_00731 5.18e-250 - - - S - - - Glycosyl hydrolase
HNMJCOBO_00732 2.03e-306 yvbW - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
HNMJCOBO_00733 2.37e-199 yvbV - - EG - - - EamA-like transporter family
HNMJCOBO_00734 3.45e-206 yvbU - - K - - - Transcriptional regulator
HNMJCOBO_00735 1.04e-245 yvbT - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HNMJCOBO_00736 1.51e-258 araR - - K ko:K02103 - ko00000,ko03000 transcriptional
HNMJCOBO_00737 0.0 araE - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HNMJCOBO_00738 2.42e-237 cggR - - K ko:K05311 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HNMJCOBO_00739 5.72e-238 gapA 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HNMJCOBO_00740 1.97e-277 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
HNMJCOBO_00741 2.12e-176 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HNMJCOBO_00742 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and
HNMJCOBO_00743 1.38e-309 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HNMJCOBO_00744 2.4e-106 yvbK - - K - - - acetyltransferase
HNMJCOBO_00745 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
HNMJCOBO_00746 2.38e-158 yvbI - - M - - - Membrane
HNMJCOBO_00747 1.03e-145 yvbH - - S - - - YvbH-like oligomerisation region
HNMJCOBO_00748 9.68e-136 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
HNMJCOBO_00749 1.74e-130 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
HNMJCOBO_00750 5.58e-270 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HNMJCOBO_00751 5.63e-145 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
HNMJCOBO_00752 2.58e-223 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HNMJCOBO_00753 1.03e-146 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
HNMJCOBO_00754 9.63e-60 sdpR - - K - - - transcriptional
HNMJCOBO_00755 1.13e-130 yvaZ - - S - - - Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
HNMJCOBO_00757 6.52e-222 - - - - - - - -
HNMJCOBO_00758 8.13e-10 - - - S - - - Sporulation delaying protein SdpA
HNMJCOBO_00759 1.15e-122 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
HNMJCOBO_00760 6.29e-272 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HNMJCOBO_00761 1.55e-142 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
HNMJCOBO_00762 2.89e-221 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HNMJCOBO_00763 2.26e-144 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
HNMJCOBO_00764 0.0 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
HNMJCOBO_00765 3.85e-72 yvaP - - K - - - transcriptional
HNMJCOBO_00766 1.19e-92 yvaO - - K ko:K22299 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
HNMJCOBO_00767 4.08e-92 yvaO - - K ko:K22299 - ko00000,ko03000 transcriptional
HNMJCOBO_00768 3.44e-48 yvzC - - K - - - transcriptional
HNMJCOBO_00769 4.03e-196 yvaM 1.11.1.10 - S ko:K00433 - ko00000,ko01000 Serine aminopeptidase, S33
HNMJCOBO_00770 1.87e-35 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
HNMJCOBO_00771 3.43e-183 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Carboxylesterase
HNMJCOBO_00772 0.0 rnr - - K ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HNMJCOBO_00773 2.4e-107 smpB - - O ko:K03664 - ko00000 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HNMJCOBO_00775 3.96e-182 yvaG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
HNMJCOBO_00776 8.9e-131 - - - K - - - Bacterial regulatory proteins, tetR family
HNMJCOBO_00777 4.28e-72 yvaE - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
HNMJCOBO_00778 2.02e-97 yvaD - - S - - - Family of unknown function (DUF5360)
HNMJCOBO_00779 0.0 - - - S - - - Fusaric acid resistance protein-like
HNMJCOBO_00780 3.59e-154 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HNMJCOBO_00781 7.89e-254 yvaA 1.1.1.371 - S ko:K16044 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
HNMJCOBO_00782 6.89e-65 csoR - - S ko:K21600 - ko00000,ko03000 transcriptional
HNMJCOBO_00783 3.66e-41 copZ - - P ko:K07213 ko04978,map04978 ko00000,ko00001 Copper resistance protein CopZ
HNMJCOBO_00784 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
HNMJCOBO_00785 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
HNMJCOBO_00786 3.45e-137 bdbD - - O - - - Thioredoxin
HNMJCOBO_00787 1.99e-95 bdbC - - O ko:K03611 - ko00000,ko03110 Required for disulfide bond formation in some proteins
HNMJCOBO_00788 3.88e-140 yvgT - - S - - - membrane
HNMJCOBO_00789 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
HNMJCOBO_00790 0.0 cysJ 1.8.1.2 - P ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HNMJCOBO_00791 0.0 cysI 1.8.1.2, 1.8.7.1 - P ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
HNMJCOBO_00792 0.0 yvgP - - P ko:K03316 - ko00000 COG0025 NhaP-type Na H and K H antiporters
HNMJCOBO_00793 7.97e-113 yvgO - - - - - - -
HNMJCOBO_00794 4.54e-203 yvgN - - S - - - reductase
HNMJCOBO_00795 6.08e-154 modB - - P ko:K02018 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4149 ABC-type molybdate transport system, permease component
HNMJCOBO_00796 6.57e-179 modA - - P ko:K02020 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0725 ABC-type molybdate transport system, periplasmic component
HNMJCOBO_00797 5.58e-218 yvgK - - P ko:K07219 - ko00000 COG1910 Periplasmic molybdate-binding protein domain
HNMJCOBO_00798 0.0 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
HNMJCOBO_00799 2.38e-109 yvsG - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
HNMJCOBO_00800 9.37e-23 - - - S ko:K06427 - ko00000 Small spore protein J (Spore_SspJ)
HNMJCOBO_00801 0.0 yvsH - - E ko:K03294,ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
HNMJCOBO_00803 1.14e-227 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HNMJCOBO_00804 1.48e-237 fhuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HNMJCOBO_00805 4.78e-226 fhuG - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HNMJCOBO_00806 2.92e-191 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HNMJCOBO_00807 3.61e-231 - - - M ko:K02005 - ko00000 Efflux transporter rnd family, mfp subunit
HNMJCOBO_00808 1.62e-159 yvrO - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HNMJCOBO_00809 1.17e-272 yvrN - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
HNMJCOBO_00810 9.89e-86 yvrL - - S - - - Regulatory protein YrvL
HNMJCOBO_00811 9.23e-292 oxdC 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
HNMJCOBO_00812 1.41e-25 - - - S - - - YvrJ protein family
HNMJCOBO_00813 5.77e-127 yvrI - - K ko:K03093 - ko00000,ko03021 RNA polymerase
HNMJCOBO_00814 6.16e-33 - - - - - - - -
HNMJCOBO_00815 1.1e-170 yvrH - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HNMJCOBO_00816 0.0 yvrG - - T - - - Histidine kinase
HNMJCOBO_00817 2.19e-218 yvrE - - G ko:K14274 ko00040,map00040 ko00000,ko00001,ko01000 SMP-30/Gluconolaconase/LRE-like region
HNMJCOBO_00818 2.12e-181 yvrD - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HNMJCOBO_00819 7.01e-217 btuF - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
HNMJCOBO_00820 3.67e-234 btuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HNMJCOBO_00821 1.82e-309 yvrA 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
HNMJCOBO_00822 9.2e-130 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Adenosyltransferase
HNMJCOBO_00823 1.13e-288 yvqJ - - EGP - - - COG0477 Permeases of the major facilitator superfamily
HNMJCOBO_00824 1.51e-82 liaI - - S ko:K11619 ko02020,map02020 ko00000,ko00001,ko00002 membrane
HNMJCOBO_00825 9.94e-143 liaH - - KT ko:K03969,ko:K11620 ko02020,map02020 ko00000,ko00001,ko00002 COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
HNMJCOBO_00826 1.16e-171 liaG - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
HNMJCOBO_00827 5.39e-164 - - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
HNMJCOBO_00828 6.73e-245 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HNMJCOBO_00829 5.43e-140 vraR - - KT ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HNMJCOBO_00830 1.45e-241 gerAC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination B3/ GerAC like, C-terminal
HNMJCOBO_00831 9.69e-252 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
HNMJCOBO_00832 0.0 gerAA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
HNMJCOBO_00833 4.48e-34 - - - S - - - Protein of unknown function (DUF3970)
HNMJCOBO_00834 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HNMJCOBO_00835 3.06e-204 yuxN - - K - - - Transcriptional regulator
HNMJCOBO_00836 0.0 cssS 2.7.13.3 - T ko:K07650 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HNMJCOBO_00837 2.23e-164 cssR - - T ko:K07770 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HNMJCOBO_00838 2.07e-300 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HNMJCOBO_00839 1.51e-104 fri - - P ko:K04047 - ko00000,ko03036 Ferritin-like domain
HNMJCOBO_00840 4.69e-177 yusZ - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HNMJCOBO_00841 5.75e-160 - 2.3.1.29 - H ko:K00639 ko00260,map00260 ko00000,ko00001,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HNMJCOBO_00842 1.26e-18 - - - - - - - -
HNMJCOBO_00844 3.05e-20 - - - S - - - Evidence 4 Homologs of previously reported genes of
HNMJCOBO_00846 2.94e-17 - - - EGP - - - Major Facilitator
HNMJCOBO_00847 6.4e-09 - - - J - - - O-methyltransferase
HNMJCOBO_00848 3.54e-95 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC superfamily ATP binding cassette transporter ABC protein
HNMJCOBO_00849 2.98e-14 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
HNMJCOBO_00851 0.0 pepF2 - - E - - - COG1164 Oligoendopeptidase F
HNMJCOBO_00852 3.48e-88 - - - S - - - YusW-like protein
HNMJCOBO_00853 8.74e-196 yusV 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HNMJCOBO_00854 3.99e-53 yusU - - S - - - Protein of unknown function (DUF2573)
HNMJCOBO_00855 2.41e-203 gltR - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
HNMJCOBO_00856 7.05e-138 yusR 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
HNMJCOBO_00857 2.93e-85 yusQ - - S - - - Tautomerase enzyme
HNMJCOBO_00858 0.0 yusP - - P - - - Major facilitator superfamily
HNMJCOBO_00859 3.83e-99 yusO - - K - - - Iron dependent repressor, N-terminal DNA binding domain
HNMJCOBO_00860 8.66e-70 yusN - - M - - - Coat F domain
HNMJCOBO_00861 2.23e-54 - - - - - - - -
HNMJCOBO_00862 3.46e-211 fadM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
HNMJCOBO_00863 1.11e-13 - - - S - - - YuzL-like protein
HNMJCOBO_00864 0.0 fadN 1.1.1.35 - I ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 ko00000,ko00001,ko00002,ko01000 3-hydroxyacyl-CoA dehydrogenase
HNMJCOBO_00865 3.15e-277 fadA 2.3.1.16 - I ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the thiolase family
HNMJCOBO_00866 0.0 fadE 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
HNMJCOBO_00867 1.01e-83 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
HNMJCOBO_00868 5.91e-85 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
HNMJCOBO_00869 7.34e-54 yusG - - S - - - Protein of unknown function (DUF2553)
HNMJCOBO_00870 7.62e-97 yusF - - L ko:K07476 - ko00000 COG1658 Small primase-like proteins (Toprim domain)
HNMJCOBO_00871 2e-73 yusE - - CO - - - Thioredoxin
HNMJCOBO_00872 1.26e-73 yusD - - S - - - SCP-2 sterol transfer family
HNMJCOBO_00873 2.15e-236 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HNMJCOBO_00874 6.5e-126 metI - - P ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2011 ABC-type metal ion transport system, permease component
HNMJCOBO_00875 1.01e-189 metQ - - P ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
HNMJCOBO_00876 5.44e-81 yurZ - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HNMJCOBO_00877 3.82e-183 sufC - - O ko:K09013 - ko00000,ko02000 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
HNMJCOBO_00878 7.43e-313 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
HNMJCOBO_00879 2.81e-299 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HNMJCOBO_00880 6.26e-101 nifU - - C ko:K04488 - ko00000 COG0822 NifU homolog involved in Fe-S cluster formation
HNMJCOBO_00881 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 FeS cluster assembly
HNMJCOBO_00882 2.14e-87 yurT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HNMJCOBO_00883 3.35e-56 - - - - - - - -
HNMJCOBO_00885 1.42e-268 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
HNMJCOBO_00886 1.2e-87 yurQ - - L - - - COG0322 Nuclease subunit of the excinuclease complex
HNMJCOBO_00887 2.24e-236 frlB - - M ko:K10708 - ko00000,ko01000 Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
HNMJCOBO_00888 2.46e-308 yurO - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
HNMJCOBO_00889 3.54e-199 yurN - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HNMJCOBO_00890 1.94e-216 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
HNMJCOBO_00891 9.57e-209 - 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
HNMJCOBO_00892 7.46e-176 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
HNMJCOBO_00893 2.95e-263 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HNMJCOBO_00894 1.32e-217 bsn - - L - - - Ribonuclease
HNMJCOBO_00895 1.38e-293 pucF 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
HNMJCOBO_00896 3.32e-303 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
HNMJCOBO_00897 2.24e-237 pucA 1.17.1.4 - O ko:K00087,ko:K07402 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HNMJCOBO_00898 3.58e-142 pucB 1.17.1.4, 2.7.7.76 - S ko:K00087,ko:K07141 ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120 ko00000,ko00001,ko00002,ko01000 MobA-like NTP transferase domain
HNMJCOBO_00899 1.17e-185 pucC 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03519 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
HNMJCOBO_00900 0.0 pucD 1.17.1.4 - C ko:K00087 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
HNMJCOBO_00901 8.45e-123 - 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03518 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
HNMJCOBO_00902 7.56e-75 pucM 3.5.2.17 - S ko:K07127 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
HNMJCOBO_00903 0.0 - 1.7.3.3, 4.1.1.97 - Q ko:K16838 ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
HNMJCOBO_00904 1.43e-276 pbuX - - F ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
HNMJCOBO_00905 4.67e-297 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 Permease family
HNMJCOBO_00906 0.0 pucR - - QT ko:K09684 - ko00000,ko03000 COG2508 Regulator of polyketide synthase expression
HNMJCOBO_00907 0.0 allB 3.5.2.5 - F ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
HNMJCOBO_00908 2.72e-82 yunG - - - - - - -
HNMJCOBO_00909 4.26e-220 yunF - - S - - - Protein of unknown function DUF72
HNMJCOBO_00910 1.31e-180 yunE - - S ko:K07090 - ko00000 membrane transporter protein
HNMJCOBO_00911 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
HNMJCOBO_00912 3.41e-65 yunC - - S - - - Domain of unknown function (DUF1805)
HNMJCOBO_00913 4.25e-172 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
HNMJCOBO_00914 2.66e-252 lytH - - M ko:K21472 - ko00000,ko01000,ko01002,ko01011 Peptidase, M23
HNMJCOBO_00915 1.37e-215 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HNMJCOBO_00916 9.45e-145 yutC - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HNMJCOBO_00917 3.2e-63 yutD - - S - - - protein conserved in bacteria
HNMJCOBO_00918 2.38e-99 yutE - - S - - - Protein of unknown function DUF86
HNMJCOBO_00919 3.69e-183 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HNMJCOBO_00920 2.26e-101 yutG 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
HNMJCOBO_00921 4.63e-255 yutH - - S - - - Spore coat protein
HNMJCOBO_00922 3.36e-307 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
HNMJCOBO_00923 2.4e-253 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HNMJCOBO_00924 1.22e-219 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HNMJCOBO_00925 0.0 yuxL 3.4.19.1 - EU ko:K01303 - ko00000,ko01000,ko01002 peptidase
HNMJCOBO_00926 1.26e-47 yutI - - O - - - COG0694 Thioredoxin-like proteins and domains
HNMJCOBO_00927 6.61e-75 yuzD - - S - - - protein conserved in bacteria
HNMJCOBO_00928 1.12e-253 yutJ 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
HNMJCOBO_00929 1.74e-52 yuzB - - S - - - Belongs to the UPF0349 family
HNMJCOBO_00930 6.25e-270 yutK - - F ko:K03317 - ko00000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HNMJCOBO_00931 3.9e-208 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HNMJCOBO_00932 6.81e-83 erpA - - S ko:K13628 - ko00000,ko03016 Belongs to the HesB IscA family
HNMJCOBO_00933 6.88e-116 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HNMJCOBO_00934 2.96e-151 paiB - - K ko:K07734 - ko00000,ko03000 Putative FMN-binding domain
HNMJCOBO_00935 1.15e-237 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HNMJCOBO_00937 1.16e-240 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 reductase
HNMJCOBO_00938 4.16e-301 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
HNMJCOBO_00939 1.97e-46 yuiB - - S - - - Putative membrane protein
HNMJCOBO_00940 3.27e-149 yuiC - - S - - - protein conserved in bacteria
HNMJCOBO_00941 8.63e-102 yuiD - - S ko:K09775 - ko00000 protein conserved in bacteria
HNMJCOBO_00942 0.0 pepA 3.4.11.1 - E ko:K01255 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HNMJCOBO_00943 3.65e-279 yuiF - - S ko:K07084 - ko00000,ko02000 antiporter
HNMJCOBO_00944 8.33e-125 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Biotin biosynthesis protein
HNMJCOBO_00945 2.36e-157 yuiH - - S - - - Oxidoreductase molybdopterin binding domain
HNMJCOBO_00946 1.55e-213 eSD - - S ko:K07017 - ko00000 Putative esterase
HNMJCOBO_00947 1.43e-178 dhbA 1.3.1.28 - IQ ko:K00216 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
HNMJCOBO_00948 7.34e-291 dhbC 5.4.4.2 - HQ ko:K02361 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
HNMJCOBO_00949 0.0 entE 2.7.7.58, 6.3.2.14 - Q ko:K02363,ko:K04783 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 2,3-dihydroxybenzoate-AMP ligase
HNMJCOBO_00950 3.83e-229 dhbB 3.3.2.1, 6.3.2.14 - Q ko:K01252 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 Isochorismatase family
HNMJCOBO_00951 0.0 dhbF - - Q ko:K04780 ko01053,map01053 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HNMJCOBO_00952 1.42e-47 mbtH - - S ko:K05375 ko00261,ko01130,map00261,map01130 ko00000,ko00001,ko00002 MbtH-like protein
HNMJCOBO_00953 2.07e-169 yukJ - - S - - - Uncharacterized conserved protein (DUF2278)
HNMJCOBO_00954 4.9e-263 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
HNMJCOBO_00955 1.03e-292 yukF - - QT - - - Transcriptional regulator
HNMJCOBO_00956 3.93e-60 yukE - - S - - - Belongs to the WXG100 family
HNMJCOBO_00957 1.93e-54 yukD - - S - - - WXG100 protein secretion system (Wss), protein YukD
HNMJCOBO_00958 4.28e-271 essB - - S - - - WXG100 protein secretion system (Wss), protein YukC
HNMJCOBO_00959 0.0 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HNMJCOBO_00960 0.0 yueB - - S - - - type VII secretion protein EsaA
HNMJCOBO_00961 4.37e-97 yueC - - S - - - Family of unknown function (DUF5383)
HNMJCOBO_00962 6.1e-171 yueD 1.1.1.320 - IQ ko:K16216 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HNMJCOBO_00963 1.91e-125 yueE - - S ko:K06950 - ko00000 phosphohydrolase
HNMJCOBO_00964 8.4e-33 - - - S - - - Protein of unknown function (DUF2642)
HNMJCOBO_00965 3.97e-93 - - - S - - - Protein of unknown function (DUF2283)
HNMJCOBO_00966 4.72e-245 yueF - - S - - - transporter activity
HNMJCOBO_00967 1.23e-43 yueG - - S ko:K06299 - ko00000 Spore germination protein gerPA/gerPF
HNMJCOBO_00968 1.63e-52 yueH - - S - - - YueH-like protein
HNMJCOBO_00969 1.32e-88 - - - S - - - Protein of unknown function (DUF1694)
HNMJCOBO_00970 5.65e-135 pncA - - Q ko:K16788 - ko00000,ko02000 COG1335 Amidases related to nicotinamidase
HNMJCOBO_00971 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HNMJCOBO_00972 2.92e-298 yuxH - - T - - - signal transduction protein containing EAL and modified HD-GYP domains
HNMJCOBO_00973 9.63e-08 - - - - - - - -
HNMJCOBO_00974 6.29e-10 - - - S - - - DegQ (SacQ) family
HNMJCOBO_00975 1.4e-209 comQ - - H ko:K02251 ko02024,map02024 ko00000,ko00001,ko02044 Polyprenyl synthetase
HNMJCOBO_00977 0.0 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HNMJCOBO_00978 2.06e-150 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HNMJCOBO_00979 3.18e-84 yuxO - - Q - - - protein, possibly involved in aromatic compounds catabolism
HNMJCOBO_00980 5.97e-79 mrpG - - P ko:K05571 - ko00000,ko02000 COG1320 Multisubunit Na H antiporter, MnhG subunit
HNMJCOBO_00981 2.23e-51 mrpF - - P ko:K05570 - ko00000,ko02000 Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HNMJCOBO_00982 2.12e-102 mrpE - - P ko:K05569 - ko00000,ko02000 Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HNMJCOBO_00983 0.0 mrpD - - CP ko:K05568 - ko00000,ko02000 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HNMJCOBO_00984 1.72e-66 mrpC - - P ko:K05567 - ko00000,ko02000 Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HNMJCOBO_00985 7.66e-91 mrpB - - P ko:K05566 - ko00000,ko02000 Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HNMJCOBO_00986 0.0 mrpA - - CP ko:K05565 - ko00000,ko02000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HNMJCOBO_00987 7.06e-22 - - - - - - - -
HNMJCOBO_00988 9.73e-310 malP - - C ko:K11616 ko02020,map02020 ko00000,ko00001 COG3493 Na citrate symporter
HNMJCOBO_00989 1.47e-216 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HNMJCOBO_00990 1.57e-237 yufP - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HNMJCOBO_00991 0.0 yufO 3.6.3.17 - S ko:K02056 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HNMJCOBO_00992 6.34e-254 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
HNMJCOBO_00993 1.14e-162 dcuR - - T ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
HNMJCOBO_00994 0.0 malK 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
HNMJCOBO_00995 4.19e-113 yufK - - S - - - Family of unknown function (DUF5366)
HNMJCOBO_00996 3.31e-98 yuxK - - S - - - protein conserved in bacteria
HNMJCOBO_00997 0.0 pbpD 2.4.1.129, 3.4.16.4 GT51 M ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin-binding Protein
HNMJCOBO_00998 1.96e-245 yuxJ - - EGP - - - Major facilitator superfamily
HNMJCOBO_01000 8.49e-150 kapD - - L ko:K06348 - ko00000 the KinA pathway to sporulation
HNMJCOBO_01001 4.3e-92 kapB - - G ko:K06347 ko02020,map02020 ko00000,ko00001 Kinase associated protein B
HNMJCOBO_01002 1.06e-296 kinB2 2.7.13.3 - T ko:K07697 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HNMJCOBO_01003 2.09e-289 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
HNMJCOBO_01004 1.58e-54 yugE - - S - - - Domain of unknown function (DUF1871)
HNMJCOBO_01005 1.2e-201 yugF - - I - - - Hydrolase
HNMJCOBO_01006 6.74e-112 alaR - - K - - - Transcriptional regulator
HNMJCOBO_01007 5.43e-255 yugH - - E ko:K10907 - ko00000,ko01000,ko01007 Aminotransferase
HNMJCOBO_01008 5e-83 yugI - - J ko:K07570,ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
HNMJCOBO_01009 2.21e-46 yuzA - - S ko:K09779 - ko00000 Domain of unknown function (DUF378)
HNMJCOBO_01010 2.85e-287 yugJ - - C ko:K19955 - ko00000,ko01000 oxidoreductases, Fe-dependent alcohol dehydrogenase family
HNMJCOBO_01011 5.56e-291 yugK - - C ko:K19955 - ko00000,ko01000 Dehydrogenase
HNMJCOBO_01012 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
HNMJCOBO_01014 4.22e-95 yugN - - S - - - YugN-like family
HNMJCOBO_01015 3.56e-233 yugO - - P ko:K10716 - ko00000,ko02000 COG1226 Kef-type K transport systems
HNMJCOBO_01016 2.12e-70 mstX - - S - - - Membrane-integrating protein Mistic
HNMJCOBO_01017 2.16e-48 - - - - - - - -
HNMJCOBO_01018 4.8e-150 yugP - - S ko:K06973 - ko00000 Zn-dependent protease
HNMJCOBO_01019 2.52e-300 yugS - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
HNMJCOBO_01020 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
HNMJCOBO_01021 3.63e-95 yugU - - S - - - Uncharacterised protein family UPF0047
HNMJCOBO_01022 2.04e-47 - - - - - - - -
HNMJCOBO_01023 6.15e-181 tgl 2.3.2.13 - H ko:K00686 - ko00000,ko01000 Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
HNMJCOBO_01024 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
HNMJCOBO_01025 2.29e-295 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
HNMJCOBO_01026 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
HNMJCOBO_01027 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
HNMJCOBO_01028 0.0 yuxG - - IQ - - - Class II Aldolase and Adducin N-terminal domain
HNMJCOBO_01029 1.04e-170 yulB - - K ko:K02530,ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
HNMJCOBO_01030 0.0 rhaB 2.7.1.5 - G ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
HNMJCOBO_01031 4.94e-73 rhaM 5.1.3.32 - G ko:K03534 - ko00000,ko01000 Involved in the anomeric conversion of L-rhamnose
HNMJCOBO_01032 0.0 rhaA 2.7.1.5, 5.3.1.14 - G ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Belongs to the rhamnose isomerase family
HNMJCOBO_01033 9.11e-236 yulF - - S ko:K22230 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
HNMJCOBO_01034 1.73e-252 yubA - - S - - - transporter activity
HNMJCOBO_01035 1.73e-182 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HNMJCOBO_01037 3.95e-113 cdoA 1.13.11.20 - S ko:K00456 ko00270,ko00430,ko01100,map00270,map00430,map01100 ko00000,ko00001,ko01000 Cysteine dioxygenase type I
HNMJCOBO_01038 0.0 yubD - - P - - - Major Facilitator Superfamily
HNMJCOBO_01039 1.87e-196 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HNMJCOBO_01040 3.31e-52 yubF - - S - - - yiaA/B two helix domain
HNMJCOBO_01041 3.57e-299 - - - P ko:K03498 - ko00000,ko02000 Potassium
HNMJCOBO_01042 2.14e-156 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
HNMJCOBO_01043 5.83e-118 yuaB - - - - - - -
HNMJCOBO_01044 2.39e-121 yuaC - - K ko:K22109 - ko00000,ko03000 Belongs to the GbsR family
HNMJCOBO_01045 0.0 gbsA 1.2.1.8 - C ko:K00130 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
HNMJCOBO_01046 4.26e-292 gbsB 1.1.1.1 - C ko:K11440 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
HNMJCOBO_01047 1.42e-137 yuaD - - - - - - -
HNMJCOBO_01048 1.95e-109 yuaE - - S - - - DinB superfamily
HNMJCOBO_01049 1.68e-109 yuaF - - OU - - - Membrane protein implicated in regulation of membrane protease activity
HNMJCOBO_01050 9.14e-258 yuaG - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 protein conserved in bacteria
HNMJCOBO_01051 3.31e-120 - - - M - - - FR47-like protein
HNMJCOBO_01052 2.52e-122 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
HNMJCOBO_01071 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HNMJCOBO_01072 8.49e-265 glgC 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HNMJCOBO_01073 1.58e-239 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Glucose-1-phosphate adenylyltransferase, GlgD subunit
HNMJCOBO_01074 0.0 glgA 2.4.1.21 GT5 G ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
HNMJCOBO_01075 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HNMJCOBO_01076 1.97e-101 ytaB - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 membrane
HNMJCOBO_01077 9.43e-263 cotI - - S ko:K06331 - ko00000 Spore coat protein
HNMJCOBO_01078 1.75e-276 cotSA - - M ko:K06338 - ko00000 Glycosyl transferases group 1
HNMJCOBO_01079 9.85e-263 cotS - - S ko:K06337 - ko00000 Seems to be required for the assembly of the CotSA protein in spores
HNMJCOBO_01081 8.35e-297 - - - M ko:K06338 - ko00000 Glycosyltransferase Family 4
HNMJCOBO_01082 3.15e-230 ytcB - - M - - - NAD-dependent epimerase dehydratase
HNMJCOBO_01083 2.03e-310 ytcA 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HNMJCOBO_01084 1.7e-196 ytdA 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
HNMJCOBO_01085 8.68e-169 yteA - - T - - - COG1734 DnaK suppressor protein
HNMJCOBO_01086 0.0 menF 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
HNMJCOBO_01087 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HNMJCOBO_01088 5.09e-199 menH 4.2.99.20 - S ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
HNMJCOBO_01089 3.45e-200 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HNMJCOBO_01090 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HNMJCOBO_01091 7.07e-273 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
HNMJCOBO_01092 1.13e-218 troA - - P ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
HNMJCOBO_01093 1.83e-180 mntB 3.6.3.35 - P ko:K02074,ko:K09820,ko:K11710,ko:K19973 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HNMJCOBO_01094 1.64e-299 mntC - - P ko:K11705,ko:K11708,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HNMJCOBO_01095 9.65e-194 mntD - - P ko:K11709,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
HNMJCOBO_01096 2.43e-34 - - - S - - - Domain of Unknown Function (DUF1540)
HNMJCOBO_01097 2.96e-241 ythB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG1294 Cytochrome bd-type quinol oxidase, subunit 2
HNMJCOBO_01098 1.03e-315 ythA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
HNMJCOBO_01099 5.02e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
HNMJCOBO_01100 8.96e-134 ytiB 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
HNMJCOBO_01101 8.36e-113 luxS 4.4.1.21 - T ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HNMJCOBO_01102 8.26e-96 ytkA - - S - - - YtkA-like
HNMJCOBO_01104 1.8e-99 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
HNMJCOBO_01105 1.59e-81 ytkC - - S - - - Bacteriophage holin family
HNMJCOBO_01106 4.47e-113 ytkD 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
HNMJCOBO_01107 1.32e-183 ytlD - - P ko:K02050 - ko00000,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HNMJCOBO_01108 1.5e-184 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HNMJCOBO_01109 2.77e-242 ytlA - - P ko:K02051 - ko00000,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
HNMJCOBO_01110 6.67e-191 ytmA - - E - - - COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
HNMJCOBO_01111 2.85e-52 ytmB - - S - - - Protein of unknown function (DUF2584)
HNMJCOBO_01112 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HNMJCOBO_01113 2.26e-286 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HNMJCOBO_01114 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
HNMJCOBO_01115 0.0 ytnA - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
HNMJCOBO_01116 8.35e-88 ytoA - - S - - - COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HNMJCOBO_01117 2.33e-192 ytpA 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Alpha beta hydrolase
HNMJCOBO_01118 4.81e-276 ytpB 4.2.3.130 - S ko:K16188 - ko00000,ko01000 Tetraprenyl-beta-curcumene synthase
HNMJCOBO_01119 6.76e-137 ytqB - - J - - - Putative rRNA methylase
HNMJCOBO_01120 4.06e-245 ytqA - - S ko:K07139 - ko00000 Fe-S oxidoreductase
HNMJCOBO_01121 1.27e-55 ytzC - - S - - - Protein of unknown function (DUF2524)
HNMJCOBO_01123 2.68e-87 ytrA - - K ko:K07979 - ko00000,ko03000 GntR family transcriptional regulator
HNMJCOBO_01124 1.03e-207 ytrB - - P ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HNMJCOBO_01125 3.35e-222 - - - P ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
HNMJCOBO_01126 1.07e-189 - - - - ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
HNMJCOBO_01127 1.02e-163 ytrE - - V ko:K16920 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HNMJCOBO_01128 5.92e-298 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
HNMJCOBO_01129 1.77e-167 graR - - T ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01504,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HNMJCOBO_01130 1.58e-239 bceS 2.7.13.3 - T ko:K11629,ko:K19077 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 His Kinase A (phosphoacceptor) domain
HNMJCOBO_01131 3.83e-179 bceA - - V ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter, ATP-binding protein
HNMJCOBO_01132 0.0 bceB - - V ko:K11632,ko:K19080 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter (permease)
HNMJCOBO_01133 4.65e-47 yttA - - S - - - Pfam Transposase IS66
HNMJCOBO_01134 1.21e-268 yttB - - EGP - - - Major facilitator superfamily
HNMJCOBO_01135 3.82e-183 pfyP - - T - - - Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
HNMJCOBO_01136 3.63e-72 ytvB - - S - - - Protein of unknown function (DUF4257)
HNMJCOBO_01137 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
HNMJCOBO_01138 1.22e-68 ytwF - - P - - - Sulfurtransferase
HNMJCOBO_01139 0.0 melA 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
HNMJCOBO_01140 8.93e-185 amyC - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
HNMJCOBO_01141 9.58e-214 amyD - - P ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HNMJCOBO_01142 6.33e-313 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
HNMJCOBO_01143 3.75e-243 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
HNMJCOBO_01144 1.6e-219 - - - S - - - Acetyl xylan esterase (AXE1)
HNMJCOBO_01145 2.73e-180 bioW 6.2.1.14 - H ko:K01906 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
HNMJCOBO_01146 0.0 bioA 2.6.1.105, 2.6.1.62 - H ko:K00833,ko:K19563 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
HNMJCOBO_01147 3.52e-273 bioF 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HNMJCOBO_01148 1.48e-155 bioD 6.3.3.3 - H ko:K01935 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HNMJCOBO_01149 1.08e-242 bioB 2.8.1.6 - H ko:K01012 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HNMJCOBO_01150 8.83e-286 bioI 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
HNMJCOBO_01151 1.28e-177 ytbQ 1.1.1.203, 1.1.1.388 - GM ko:K18981,ko:K19243 ko00030,ko00053,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00053,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 NAD dependent epimerase/dehydratase family
HNMJCOBO_01152 6.19e-193 ytcP - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
HNMJCOBO_01153 0.0 - - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
HNMJCOBO_01154 0.0 ytdP - - K - - - Transcriptional regulator
HNMJCOBO_01155 1.31e-220 lplB13 - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
HNMJCOBO_01156 1.01e-279 yteR 3.2.1.172 GH105 G ko:K15532 - ko00000,ko01000 unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
HNMJCOBO_01157 7.92e-93 yteS - - G - - - transport
HNMJCOBO_01158 0.0 yteT - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
HNMJCOBO_01159 1.97e-152 yteU - - S - - - Integral membrane protein
HNMJCOBO_01160 2.14e-36 yteV - - S - - - Sporulation protein Cse60
HNMJCOBO_01161 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
HNMJCOBO_01162 8.15e-293 ytfP - - S ko:K07007 - ko00000 HI0933-like protein
HNMJCOBO_01163 0.0 ytgP - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HNMJCOBO_01164 9.04e-171 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
HNMJCOBO_01165 4.46e-46 ytzE - - K - - - COG1349 Transcriptional regulators of sugar metabolism
HNMJCOBO_01166 2.4e-169 ythP - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HNMJCOBO_01167 8.45e-263 ythQ - - U ko:K01992 - ko00000,ko00002,ko02000 Bacterial ABC transporter protein EcsB
HNMJCOBO_01168 1.73e-288 pbuO - - S ko:K06901 - ko00000,ko02000 permease
HNMJCOBO_01169 0.0 ytjP 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Dipeptidase
HNMJCOBO_01170 3e-221 ytkP 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
HNMJCOBO_01171 7.71e-133 ytlP 3.1.4.58 - J ko:K01975 - ko00000,ko01000,ko03016 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HNMJCOBO_01172 4.92e-212 ytlQ - - - - - - -
HNMJCOBO_01173 2.22e-231 ytlR - - I - - - Diacylglycerol kinase catalytic domain
HNMJCOBO_01174 0.0 amyX 3.2.1.41 CBM48,GH13 G ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
HNMJCOBO_01175 3.02e-192 ytmP - - M - - - Phosphotransferase
HNMJCOBO_01176 9.51e-61 ytzH - - S - - - YtzH-like protein
HNMJCOBO_01177 7.53e-157 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HNMJCOBO_01178 2.16e-193 ytnP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
HNMJCOBO_01179 0.0 malS 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
HNMJCOBO_01180 4.06e-68 ytzB - - S - - - small secreted protein
HNMJCOBO_01181 3.71e-261 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
HNMJCOBO_01182 7.02e-103 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
HNMJCOBO_01183 3.17e-75 ytpP - - CO - - - Thioredoxin
HNMJCOBO_01184 1.02e-191 ytpQ - - S - - - Belongs to the UPF0354 family
HNMJCOBO_01185 1.78e-140 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HNMJCOBO_01186 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
HNMJCOBO_01187 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
HNMJCOBO_01188 1.67e-63 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HNMJCOBO_01189 3.17e-30 ytxH - - S - - - COG4980 Gas vesicle protein
HNMJCOBO_01190 1.9e-72 ytxJ - - O - - - Protein of unknown function (DUF2847)
HNMJCOBO_01191 7.64e-250 aroA 2.5.1.54, 5.4.99.5 - E ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
HNMJCOBO_01192 4.16e-235 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
HNMJCOBO_01193 1.18e-187 motP - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
HNMJCOBO_01194 1.6e-161 ytxE - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
HNMJCOBO_01195 6.51e-293 acuC - - BQ ko:K04768 - ko00000 histone deacetylase
HNMJCOBO_01196 6.16e-152 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
HNMJCOBO_01197 2.43e-156 acuA - - K ko:K04766 - ko00000,ko01000 Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
HNMJCOBO_01198 0.0 acsA 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HNMJCOBO_01199 6.47e-304 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HNMJCOBO_01201 2.01e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HNMJCOBO_01202 0.0 ytrP - - T - - - COG2199 FOG GGDEF domain
HNMJCOBO_01203 1.95e-114 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
HNMJCOBO_01204 2.94e-142 yttP - - K - - - Transcriptional regulator
HNMJCOBO_01205 3.73e-198 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 COG1387 Histidinol phosphatase and related hydrolases of the PHP family
HNMJCOBO_01206 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HNMJCOBO_01207 1.17e-304 braB - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
HNMJCOBO_01208 1.22e-269 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
HNMJCOBO_01209 6.26e-289 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HNMJCOBO_01210 2.12e-40 - - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
HNMJCOBO_01211 0.0 ytcI 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HNMJCOBO_01212 0.0 ytcJ - - S - - - amidohydrolase
HNMJCOBO_01213 2.92e-190 nadK2 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HNMJCOBO_01214 6.13e-233 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA
HNMJCOBO_01215 7.05e-113 yteJ - - S - - - RDD family
HNMJCOBO_01216 5.03e-150 ytfI - - S - - - Protein of unknown function (DUF2953)
HNMJCOBO_01217 2.24e-96 ytfJ - - S - - - Sporulation protein YtfJ
HNMJCOBO_01218 1.93e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HNMJCOBO_01219 3.78e-224 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
HNMJCOBO_01220 4.69e-281 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HNMJCOBO_01221 8.14e-115 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
HNMJCOBO_01222 1.06e-297 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
HNMJCOBO_01223 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
HNMJCOBO_01225 1.98e-182 ytkK 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HNMJCOBO_01226 1.91e-166 ytkL - - S - - - Belongs to the UPF0173 family
HNMJCOBO_01227 4.99e-223 ytlI - - K ko:K21960 - ko00000,ko03000 LysR substrate binding domain
HNMJCOBO_01228 8.39e-130 ytmI - - K ko:K00680 - ko00000,ko01000 Acetyltransferase (GNAT) domain
HNMJCOBO_01229 3.18e-195 - - - ET ko:K16956,ko:K16957,ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
HNMJCOBO_01230 4.01e-194 tcyK - - M ko:K16957 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
HNMJCOBO_01231 1.66e-157 ytmL - - P ko:K16958,ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HNMJCOBO_01232 4.76e-155 - - - U ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HNMJCOBO_01233 6.61e-183 tcyN - - E ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
HNMJCOBO_01234 1.52e-237 ytmO - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HNMJCOBO_01235 5.26e-63 ytnI - - O - - - COG0695 Glutaredoxin and related proteins
HNMJCOBO_01236 0.0 ytnJ - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HNMJCOBO_01237 1.69e-166 - 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin kinase
HNMJCOBO_01238 2.09e-306 hipO2 - - E ko:K01436,ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
HNMJCOBO_01239 2.24e-206 ytnM - - S ko:K07090 - ko00000 membrane transporter protein
HNMJCOBO_01240 1.13e-308 ytoI - - K - - - transcriptional regulator containing CBS domains
HNMJCOBO_01241 2.15e-63 ytpI - - S - - - YtpI-like protein
HNMJCOBO_01242 1.24e-230 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 COG0618 Exopolyphosphatase-related proteins
HNMJCOBO_01243 1.15e-39 - - - - - - - -
HNMJCOBO_01244 5.12e-112 ytrI - - - - - - -
HNMJCOBO_01245 2.45e-75 ytrH - - S - - - Sporulation protein YtrH
HNMJCOBO_01246 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
HNMJCOBO_01247 6.01e-287 ytsJ 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
HNMJCOBO_01248 1.35e-206 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HNMJCOBO_01249 6.63e-232 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
HNMJCOBO_01250 6.6e-229 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HNMJCOBO_01251 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
HNMJCOBO_01252 4.68e-82 fxsA - - S ko:K07113 - ko00000 COG3030 Protein affecting phage T7 exclusion by the F plasmid
HNMJCOBO_01253 4.52e-244 ytvI - - S - - - sporulation integral membrane protein YtvI
HNMJCOBO_01254 1.56e-93 ytwI - - S - - - membrane
HNMJCOBO_01255 1.17e-267 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
HNMJCOBO_01256 2.28e-309 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 isocitrate
HNMJCOBO_01257 2.55e-218 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible oxidation of malate to oxaloacetate
HNMJCOBO_01258 1.62e-169 phoP - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HNMJCOBO_01259 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
HNMJCOBO_01260 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HNMJCOBO_01261 2.01e-202 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HNMJCOBO_01262 1.68e-138 ytaF - - P - - - Probably functions as a manganese efflux pump
HNMJCOBO_01263 2.82e-126 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HNMJCOBO_01264 4.54e-205 ytbE - - S - - - reductase
HNMJCOBO_01265 5.44e-260 ytbD - - EGP ko:K19577 - ko00000,ko02000 -transporter
HNMJCOBO_01266 9.85e-88 ytcD - - K - - - Transcriptional regulator
HNMJCOBO_01267 1.22e-246 gapB 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HNMJCOBO_01268 2.42e-88 speH 4.1.1.50 - E ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
HNMJCOBO_01269 2.42e-105 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HNMJCOBO_01270 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 Membrane attachment protein
HNMJCOBO_01271 1.05e-221 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
HNMJCOBO_01272 9.77e-144 ytxB - - S - - - SNARE associated Golgi protein
HNMJCOBO_01273 5.98e-206 ytxC - - S - - - YtxC-like family
HNMJCOBO_01274 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HNMJCOBO_01275 2.07e-191 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
HNMJCOBO_01276 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HNMJCOBO_01277 2.9e-168 lytT - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
HNMJCOBO_01278 2.08e-85 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HNMJCOBO_01279 5.34e-150 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HNMJCOBO_01281 1.81e-111 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HNMJCOBO_01282 3.93e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
HNMJCOBO_01283 3.26e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HNMJCOBO_01284 1.27e-59 ysdA - - S - - - Membrane
HNMJCOBO_01285 1.96e-89 ysdB - - S - - - Sigma-w pathway protein YsdB
HNMJCOBO_01286 4.35e-262 ysdC - - G - - - COG1363 Cellulase M and related proteins
HNMJCOBO_01287 4.21e-243 - 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
HNMJCOBO_01288 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
HNMJCOBO_01289 0.0 araB 2.7.1.16 - C ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Belongs to the ribulokinase family
HNMJCOBO_01290 1.7e-170 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
HNMJCOBO_01291 6.06e-187 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
HNMJCOBO_01292 3.05e-281 araM 1.1.1.261 - I ko:K00096 ko00564,map00564 ko00000,ko00001,ko01000 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
HNMJCOBO_01293 0.0 araN - - G ko:K17234 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
HNMJCOBO_01294 1.94e-218 araP - - G ko:K17235 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
HNMJCOBO_01295 2.47e-189 araQ - - G ko:K17236 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport system permease
HNMJCOBO_01296 0.0 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 alpha-L-arabinofuranosidase activity
HNMJCOBO_01297 0.0 cstA - - T ko:K06200 - ko00000 Carbon starvation protein
HNMJCOBO_01299 8.17e-52 ysfE 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 lactoylglutathione lyase activity
HNMJCOBO_01300 0.0 glcF - - C ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 Glycolate oxidase
HNMJCOBO_01301 0.0 glcD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Glycolate oxidase subunit
HNMJCOBO_01302 6.71e-265 cdaR_1 - - KT ko:K02647 - ko00000,ko03000 regulator
HNMJCOBO_01303 7.54e-44 sspI - - S ko:K06426 - ko00000 Belongs to the SspI family
HNMJCOBO_01304 7.68e-172 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HNMJCOBO_01305 1.81e-250 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HNMJCOBO_01306 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HNMJCOBO_01307 6.77e-219 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HNMJCOBO_01308 1.04e-54 zapA - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HNMJCOBO_01309 1.09e-111 yshB - - S - - - membrane protein, required for colicin V production
HNMJCOBO_01310 0.0 polX - - L ko:K02347 - ko00000,ko03400 COG1796 DNA polymerase IV (family X)
HNMJCOBO_01311 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HNMJCOBO_01312 3.76e-89 yshE - - S ko:K08989 - ko00000 membrane
HNMJCOBO_01313 0.0 lcfA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HNMJCOBO_01314 1.21e-130 fadR - - K ko:K13770 - ko00000,ko03000 Transcriptional regulator
HNMJCOBO_01315 2.2e-176 fadB 4.2.1.17 - I ko:K13767 ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the enoyl-CoA hydratase isomerase family
HNMJCOBO_01316 2.58e-179 etfB - - C ko:K03521 - ko00000 Electron transfer flavoprotein
HNMJCOBO_01317 1.23e-227 etfA - - C ko:K03522 - ko00000,ko04147 Electron transfer flavoprotein
HNMJCOBO_01319 0.0 xsa 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
HNMJCOBO_01320 1.12e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
HNMJCOBO_01321 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HNMJCOBO_01322 4.83e-276 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
HNMJCOBO_01323 8.53e-104 yslB - - S - - - Protein of unknown function (DUF2507)
HNMJCOBO_01324 1.35e-140 sdhC - - C ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 succinate dehydrogenase
HNMJCOBO_01325 0.0 sdhA 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
HNMJCOBO_01326 1.15e-189 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
HNMJCOBO_01327 2.65e-102 ysmA - - S ko:K07107 - ko00000,ko01000 thioesterase
HNMJCOBO_01328 1.81e-41 gerE - - K ko:K01994 - ko00000,ko03000 Transcriptional regulator
HNMJCOBO_01329 1.6e-98 ysmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
HNMJCOBO_01330 4.49e-194 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
HNMJCOBO_01331 8.03e-256 gerM - - S ko:K06298 - ko00000 COG5401 Spore germination protein
HNMJCOBO_01332 3.53e-171 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HNMJCOBO_01333 1.06e-132 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HNMJCOBO_01334 4.05e-119 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
HNMJCOBO_01336 1.01e-184 ysnF - - S - - - protein conserved in bacteria
HNMJCOBO_01337 3.32e-107 ysnE - - K ko:K03829 - ko00000,ko01000 acetyltransferase
HNMJCOBO_01339 0.0 ilvB 2.2.1.6 - E ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
HNMJCOBO_01340 5.05e-110 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
HNMJCOBO_01341 9.59e-245 ilvC 1.1.1.86 - EH ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HNMJCOBO_01342 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HNMJCOBO_01343 1.06e-255 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HNMJCOBO_01344 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HNMJCOBO_01345 5.35e-150 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HNMJCOBO_01346 2.73e-240 ysoA - - H - - - Tetratricopeptide repeat
HNMJCOBO_01347 8.87e-287 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HNMJCOBO_01348 1.15e-296 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HNMJCOBO_01349 0.0 lonB 3.4.21.53 - LO ko:K04076 - ko00000,ko01000,ko01002 Belongs to the peptidase S16 family
HNMJCOBO_01350 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HNMJCOBO_01351 7.6e-139 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
HNMJCOBO_01352 8.23e-117 ysxD - - - - - - -
HNMJCOBO_01353 6.39e-316 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HNMJCOBO_01354 6.56e-187 hemX - - O ko:K02497 - ko00000 cytochrome C
HNMJCOBO_01355 2.66e-221 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
HNMJCOBO_01356 1.57e-187 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
HNMJCOBO_01357 6.39e-234 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the ALAD family
HNMJCOBO_01358 1.05e-313 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
HNMJCOBO_01359 0.0 spoVID - - M ko:K06417 - ko00000 stage VI sporulation protein D
HNMJCOBO_01360 2.91e-253 ysxE - - S - - - A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HNMJCOBO_01361 1.53e-35 - - - - - - - -
HNMJCOBO_01362 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HNMJCOBO_01363 5.8e-316 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
HNMJCOBO_01364 3.15e-109 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
HNMJCOBO_01365 4.67e-215 spoIIB - - S ko:K06380 - ko00000 Sporulation related domain
HNMJCOBO_01366 1.73e-132 maf - - D ko:K06287 - ko00000 septum formation protein Maf
HNMJCOBO_01367 8.35e-163 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
HNMJCOBO_01368 5.26e-235 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein MreB
HNMJCOBO_01369 1.91e-202 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
HNMJCOBO_01370 8.72e-111 mreD - - M ko:K03571 - ko00000,ko03036 shape-determining protein
HNMJCOBO_01371 4.3e-158 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HNMJCOBO_01372 2.91e-186 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
HNMJCOBO_01373 1.83e-187 spoIVFA - - M ko:K06401 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
HNMJCOBO_01374 3.74e-208 spoIVFB - - S ko:K06402 - ko00000,ko01000,ko01002 Stage IV sporulation protein
HNMJCOBO_01375 6.34e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
HNMJCOBO_01376 2.66e-74 ysxB - - J ko:K07584 - ko00000 ribosomal protein
HNMJCOBO_01377 2.7e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
HNMJCOBO_01378 4.25e-139 spo0B - - T ko:K06375 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Sporulation initiation phospho-transferase B, C-terminal
HNMJCOBO_01379 9.66e-309 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HNMJCOBO_01380 4.75e-96 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
HNMJCOBO_01381 4.99e-209 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
HNMJCOBO_01382 5.02e-123 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
HNMJCOBO_01383 1.27e-294 nifS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
HNMJCOBO_01384 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
HNMJCOBO_01385 8.17e-208 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
HNMJCOBO_01386 7.94e-273 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HNMJCOBO_01387 1.71e-217 safA - - M ko:K06370 - ko00000 spore coat assembly protein SafA
HNMJCOBO_01388 7.28e-70 - - - S ko:K06345 - ko00000 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HNMJCOBO_01389 8.63e-165 yebC - - K - - - transcriptional regulatory protein
HNMJCOBO_01390 0.0 yrbD - - E ko:K03310 - ko00000 Sodium alanine symporter
HNMJCOBO_01391 2.42e-47 - - - S - - - Family of unknown function (DUF5412)
HNMJCOBO_01393 2.32e-152 yrzF - - T - - - serine threonine protein kinase
HNMJCOBO_01394 2.77e-248 idhA 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, NAD-binding Rossmann fold
HNMJCOBO_01395 0.0 csbX - - EGP - - - the major facilitator superfamily
HNMJCOBO_01396 6.46e-121 bofC - - S ko:K06318 - ko00000 BofC C-terminal domain
HNMJCOBO_01397 2.84e-137 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HNMJCOBO_01398 9.14e-239 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HNMJCOBO_01399 2.91e-30 yrzS - - S - - - Protein of unknown function (DUF2905)
HNMJCOBO_01400 6.03e-248 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HNMJCOBO_01401 4.74e-292 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HNMJCOBO_01402 1.29e-52 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit YajC
HNMJCOBO_01403 1.07e-98 yrzE - - S - - - Protein of unknown function (DUF3792)
HNMJCOBO_01404 6.34e-147 yrbG - - S - - - membrane
HNMJCOBO_01405 0.0 spoVB - - S ko:K06409 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HNMJCOBO_01406 3.2e-64 yrzD - - S - - - Post-transcriptional regulator
HNMJCOBO_01407 0.0 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HNMJCOBO_01408 6.51e-114 trkA1 - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
HNMJCOBO_01409 1.07e-64 yrvD - - S - - - Lipopolysaccharide assembly protein A domain
HNMJCOBO_01410 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
HNMJCOBO_01411 2.53e-118 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HNMJCOBO_01412 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HNMJCOBO_01413 1.36e-90 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HNMJCOBO_01414 0.0 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG3103 SH3 domain protein
HNMJCOBO_01416 1.27e-311 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
HNMJCOBO_01417 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HNMJCOBO_01418 3.96e-177 yrvM - - H ko:K22132 - ko00000,ko03016 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
HNMJCOBO_01419 8.5e-304 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
HNMJCOBO_01420 8.12e-93 cymR - - K ko:K17472 - ko00000,ko03000 Transcriptional regulator
HNMJCOBO_01421 2.67e-272 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
HNMJCOBO_01422 1.19e-280 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HNMJCOBO_01423 1.01e-20 yrrB - - S - - - COG0457 FOG TPR repeat
HNMJCOBO_01424 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HNMJCOBO_01425 1.23e-108 yrrD - - S - - - protein conserved in bacteria
HNMJCOBO_01426 8.4e-42 yrzR - - - - - - -
HNMJCOBO_01427 5.38e-12 - - - S - - - Protein of unknown function (DUF3918)
HNMJCOBO_01428 9.26e-140 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HNMJCOBO_01429 2.28e-139 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HNMJCOBO_01430 1.28e-187 glnH - - ET ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
HNMJCOBO_01431 9.37e-170 glnQ - - E ko:K09972,ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
HNMJCOBO_01432 3.07e-242 yrrI - - S - - - AI-2E family transporter
HNMJCOBO_01433 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HNMJCOBO_01434 2.22e-55 yrzL - - S - - - Belongs to the UPF0297 family
HNMJCOBO_01435 5.49e-93 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HNMJCOBO_01436 2.94e-60 yrzB - - S - - - Belongs to the UPF0473 family
HNMJCOBO_01437 7.51e-242 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HNMJCOBO_01438 1.98e-154 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-methyltransferase
HNMJCOBO_01439 6.57e-224 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
HNMJCOBO_01440 4.62e-313 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 COG0826 Collagenase and related proteases
HNMJCOBO_01441 4.51e-148 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
HNMJCOBO_01442 1.14e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HNMJCOBO_01443 0.0 pbpI - - M ko:K21468 - ko00000,ko01011 Penicillin-binding Protein
HNMJCOBO_01444 1.42e-102 yrrS - - S - - - Protein of unknown function (DUF1510)
HNMJCOBO_01445 8.52e-37 yrzA - - S - - - Protein of unknown function (DUF2536)
HNMJCOBO_01446 7.23e-155 yrrT - - Q ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Could be a S-adenosyl-L-methionine-dependent methyltransferase
HNMJCOBO_01447 1.97e-161 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HNMJCOBO_01448 7.04e-218 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Cysteine synthase
HNMJCOBO_01449 4.24e-269 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
HNMJCOBO_01450 6.93e-49 yrhC - - S - - - YrhC-like protein
HNMJCOBO_01451 4.26e-103 yrhD - - S - - - Protein of unknown function (DUF1641)
HNMJCOBO_01452 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
HNMJCOBO_01453 1.08e-80 yrhF - - S - - - Uncharacterized conserved protein (DUF2294)
HNMJCOBO_01454 1.38e-183 yrhG - - P ko:K21993 - ko00000,ko02000 Formate nitrite
HNMJCOBO_01456 9.39e-08 - - - S - - - Probable sporulation protein (Bac_small_yrzI)
HNMJCOBO_01457 1.1e-126 yrhH - - Q - - - methyltransferase
HNMJCOBO_01458 1.12e-135 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
HNMJCOBO_01459 0.0 yrhJ 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
HNMJCOBO_01460 2.67e-62 yrhK - - S - - - YrhK-like protein
HNMJCOBO_01461 0.0 oatA - - I - - - Acyltransferase family
HNMJCOBO_01462 7.4e-193 rsiV - - S - - - Protein of unknown function (DUF3298)
HNMJCOBO_01463 8.2e-113 sigV - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HNMJCOBO_01464 1.98e-192 yrhO - - K - - - Archaeal transcriptional regulator TrmB
HNMJCOBO_01465 5.63e-137 yrhP - - E - - - LysE type translocator
HNMJCOBO_01466 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
HNMJCOBO_01467 0.0 levR - - K - - - PTS system fructose IIA component
HNMJCOBO_01468 2.66e-97 levD 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11194 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
HNMJCOBO_01469 7.63e-107 ptnA 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11195 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system mannose fructose sorbose family
HNMJCOBO_01470 6.11e-168 levF - - G ko:K02746,ko:K02795,ko:K11196 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
HNMJCOBO_01471 1.39e-192 levG - - G ko:K02771,ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
HNMJCOBO_01472 0.0 sacC 3.2.1.80 - G ko:K03332 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
HNMJCOBO_01473 1.58e-116 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
HNMJCOBO_01474 8.68e-256 adhA - - C ko:K13979 - ko00000,ko01000 alcohol dehydrogenase
HNMJCOBO_01475 3.03e-40 yphJ 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 peroxiredoxin activity
HNMJCOBO_01476 3.17e-68 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
HNMJCOBO_01477 7.23e-66 yraD - - M ko:K06439 - ko00000 Spore coat protein
HNMJCOBO_01478 1.05e-36 yraE - - - ko:K06440 - ko00000 -
HNMJCOBO_01479 9.1e-284 adhB 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HNMJCOBO_01480 9.61e-84 yraF - - M - - - Spore coat protein
HNMJCOBO_01481 4.19e-50 yraG - - - ko:K06440 - ko00000 -
HNMJCOBO_01482 6.62e-87 - - - E - - - Glyoxalase-like domain
HNMJCOBO_01483 2.92e-81 - - - T - - - sh3 domain protein
HNMJCOBO_01484 6.61e-80 - - - T - - - sh3 domain protein
HNMJCOBO_01485 4.9e-200 - - - S - - - Alpha beta hydrolase
HNMJCOBO_01486 6.15e-57 yraL - - S - - - COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HNMJCOBO_01487 5.73e-202 csn 3.2.1.132 - M ko:K01233 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
HNMJCOBO_01489 7.25e-264 yraM - - S - - - PrpF protein
HNMJCOBO_01490 5.13e-211 yraN - - K - - - Transcriptional regulator
HNMJCOBO_01491 9.19e-287 yraO - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
HNMJCOBO_01492 5.96e-240 yrpG - - C - - - Aldo/keto reductase family
HNMJCOBO_01493 1.1e-124 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HNMJCOBO_01494 9.28e-170 zinT - - S ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
HNMJCOBO_01496 5.87e-163 yrpD - - S - - - Domain of unknown function, YrpD
HNMJCOBO_01497 8.73e-191 murI 5.1.1.3 - M ko:K01776 ko00471,ko01100,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
HNMJCOBO_01498 3.79e-249 npd 1.13.12.16 - S ko:K00459 ko00910,map00910 ko00000,ko00001,ko01000 COG2070 Dioxygenases related to 2-nitropropane dioxygenase
HNMJCOBO_01499 2.66e-215 aadK - - G ko:K05593 - ko00000,ko01000,ko01504 Streptomycin adenylyltransferase
HNMJCOBO_01500 1.47e-120 yrdA - - S - - - DinB family
HNMJCOBO_01501 2.28e-75 - - - S - - - Protein of unknown function (DUF2568)
HNMJCOBO_01502 7.37e-133 yrdC - - Q - - - Isochorismatase family
HNMJCOBO_01503 1.75e-295 cypA 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
HNMJCOBO_01504 1.07e-61 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
HNMJCOBO_01505 1.44e-104 bkdR - - K - - - helix_turn_helix ASNC type
HNMJCOBO_01506 9.34e-176 azlC - - E - - - AzlC protein
HNMJCOBO_01507 1.97e-66 azlD - - E - - - Branched-chain amino acid transport protein (AzlD)
HNMJCOBO_01508 7.09e-292 brnQ - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
HNMJCOBO_01510 2e-207 - - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
HNMJCOBO_01511 1.75e-87 yodA - - S - - - tautomerase
HNMJCOBO_01512 2.26e-216 czcD - - P ko:K16264 - ko00000,ko02000 COG1230 Co Zn Cd efflux system component
HNMJCOBO_01513 2.58e-255 trkA - - P ko:K07222 - ko00000 Oxidoreductase
HNMJCOBO_01514 1.2e-204 - - - K - - - Transcriptional regulator
HNMJCOBO_01515 1.53e-219 yrdR - - EG - - - EamA-like transporter family
HNMJCOBO_01516 7.28e-25 - - - S - - - YrzO-like protein
HNMJCOBO_01517 1.58e-301 yrkA - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
HNMJCOBO_01518 3.73e-109 bltD 2.3.1.57 - K ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 FR47-like protein
HNMJCOBO_01519 1.31e-269 blt - - EGP ko:K08153,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
HNMJCOBO_01520 2.15e-195 bltR - - K - - - helix_turn_helix, mercury resistance
HNMJCOBO_01522 3.81e-139 yrkC - - G - - - Cupin domain
HNMJCOBO_01523 4.38e-52 yrkD - - S - - - protein conserved in bacteria
HNMJCOBO_01524 1.96e-108 yrkE - - O - - - DsrE/DsrF/DrsH-like family
HNMJCOBO_01525 6.82e-128 yrkF - - OP - - - Belongs to the sulfur carrier protein TusA family
HNMJCOBO_01526 0.000112 perX - - S - - - DsrE/DsrF-like family
HNMJCOBO_01527 4e-261 yrkH - - P - - - Rhodanese Homology Domain
HNMJCOBO_01528 2.63e-48 yrkI - - O - - - Belongs to the sulfur carrier protein TusA family
HNMJCOBO_01529 1.21e-170 yrkJ - - S ko:K07090 - ko00000 membrane transporter protein
HNMJCOBO_01530 3.13e-104 - - - S - - - Protein of unknown function with HXXEE motif
HNMJCOBO_01531 5.71e-126 yrkL - - S ko:K11748 - ko00000,ko02000 Flavodoxin-like fold
HNMJCOBO_01532 1.33e-134 yrkN - - K - - - Acetyltransferase (GNAT) family
HNMJCOBO_01533 7.53e-283 yrkO - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
HNMJCOBO_01534 1.24e-164 yrkP - - T ko:K02483 - ko00000,ko02022 Transcriptional regulator
HNMJCOBO_01535 7.32e-306 yrkQ - - T - - - Histidine kinase
HNMJCOBO_01536 2.15e-90 psiE - - S ko:K13256 - ko00000 Protein PsiE homolog
HNMJCOBO_01537 1.42e-78 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HNMJCOBO_01538 2.63e-130 xkdA - - E - - - IrrE N-terminal-like domain
HNMJCOBO_01540 6.37e-125 yqaC - - F - - - adenylate kinase activity
HNMJCOBO_01541 4.53e-118 - - - K - - - Transcriptional regulator PadR-like family
HNMJCOBO_01542 4.54e-205 - - - S - - - Carbohydrate esterase, sialic acid-specific acetylesterase
HNMJCOBO_01545 6.1e-71 rusA - - L - - - Endodeoxyribonuclease RusA
HNMJCOBO_01546 2.49e-43 yqaO - - S - - - Phage-like element PBSX protein XtrA
HNMJCOBO_01547 9.1e-27 wapA - - M - - - COG3209 Rhs family protein
HNMJCOBO_01549 2.24e-96 yqaQ - - L - - - Transposase
HNMJCOBO_01552 2.21e-28 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
HNMJCOBO_01555 4.87e-137 - - - S - - - SEC-C Motif Domain Protein
HNMJCOBO_01556 0.000506 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
HNMJCOBO_01557 1.23e-44 yqaS - - L - - - DNA packaging
HNMJCOBO_01558 1.76e-33 yqaT - - S ko:K06909 - ko00000 phage terminase, large subunit
HNMJCOBO_01559 4.25e-165 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
HNMJCOBO_01561 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 nucleic acid phosphodiester bond hydrolysis
HNMJCOBO_01562 1.35e-91 - - - K - - - MerR family transcriptional regulator
HNMJCOBO_01563 7.42e-176 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 Reductase
HNMJCOBO_01564 7.72e-202 - - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Aspartate phosphatase response regulator
HNMJCOBO_01567 2.17e-72 arsR - - K ko:K03892 - ko00000,ko03000 ArsR family transcriptional regulator
HNMJCOBO_01568 3.34e-91 cadI 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HNMJCOBO_01569 1.18e-231 arsB - - P ko:K03325 - ko00000,ko02000 Arsenic resistance protein
HNMJCOBO_01570 2.82e-100 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Catalyzes the reduction of arsenate As(V) to arsenite As(III)
HNMJCOBO_01571 3.43e-30 - - - L - - - Helix-turn-helix domain of resolvase
HNMJCOBO_01572 5.34e-177 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
HNMJCOBO_01573 2.72e-82 - - - K - - - BetI-type transcriptional repressor, C-terminal
HNMJCOBO_01574 7.53e-161 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HNMJCOBO_01575 2.53e-97 nucB - - M - - - Deoxyribonuclease NucA/NucB
HNMJCOBO_01576 9.38e-171 - - - - - - - -
HNMJCOBO_01577 1.26e-215 yqeC 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconate dehydrogenase
HNMJCOBO_01578 9.36e-135 yqeD - - S - - - SNARE associated Golgi protein
HNMJCOBO_01579 1.68e-176 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
HNMJCOBO_01580 2.24e-182 yqeF - - E - - - GDSL-like Lipase/Acylhydrolase
HNMJCOBO_01582 2.17e-123 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
HNMJCOBO_01583 4.78e-273 yqeH - - S ko:K06948 - ko00000,ko03009 In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
HNMJCOBO_01584 4.01e-199 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HNMJCOBO_01585 8.95e-61 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein containing KH domain, possibly ribosomal protein
HNMJCOBO_01586 2.47e-141 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HNMJCOBO_01587 4.62e-131 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
HNMJCOBO_01588 6.61e-80 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HNMJCOBO_01589 9.8e-179 yqeM - - Q - - - Methyltransferase
HNMJCOBO_01590 1.1e-188 comER - - E ko:K02239 - ko00000,ko00002,ko02044 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HNMJCOBO_01591 6.65e-138 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
HNMJCOBO_01592 3.25e-137 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
HNMJCOBO_01593 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
HNMJCOBO_01594 2.36e-22 - - - S - - - YqzM-like protein
HNMJCOBO_01595 2.35e-243 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
HNMJCOBO_01596 8.09e-49 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
HNMJCOBO_01597 3.42e-258 gpr 3.4.24.78 - C ko:K06012 - ko00000,ko01000,ko01002 Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HNMJCOBO_01598 2.73e-283 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
HNMJCOBO_01599 7.06e-70 yqxA - - S - - - Protein of unknown function (DUF3679)
HNMJCOBO_01600 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HNMJCOBO_01601 2.9e-276 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
HNMJCOBO_01602 1.65e-241 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HNMJCOBO_01603 7.22e-115 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HNMJCOBO_01604 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
HNMJCOBO_01605 3.97e-256 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HNMJCOBO_01606 5.63e-226 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
HNMJCOBO_01607 1.14e-177 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HNMJCOBO_01608 0.0 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 ribosomal protein S12 methylthiotransferase
HNMJCOBO_01609 4.02e-201 yqeW - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
HNMJCOBO_01610 1.03e-26 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
HNMJCOBO_01611 2.25e-90 yqeY - - S ko:K09117 - ko00000 Yqey-like protein
HNMJCOBO_01612 7.97e-292 yqeZ - - O ko:K07403 - ko00000 COG1030 Membrane-bound serine protease (ClpP class)
HNMJCOBO_01613 4.35e-192 yqfA - - S - - - UPF0365 protein
HNMJCOBO_01614 1.4e-66 yqfB - - - - - - -
HNMJCOBO_01615 2.07e-60 yqfC - - S - - - sporulation protein YqfC
HNMJCOBO_01616 4.23e-242 yqfD - - S ko:K06438 - ko00000 Stage IV sporulation
HNMJCOBO_01617 4.99e-224 phoH - - T ko:K06217 - ko00000 Phosphate starvation-inducible protein PhoH
HNMJCOBO_01619 0.0 yqfF - - S ko:K07037 - ko00000 membrane-associated HD superfamily hydrolase
HNMJCOBO_01620 7.14e-105 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HNMJCOBO_01621 4.75e-80 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
HNMJCOBO_01622 2.73e-92 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HNMJCOBO_01623 9.98e-215 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HNMJCOBO_01624 5.29e-27 - - - S - - - YqzL-like protein
HNMJCOBO_01625 5.26e-187 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
HNMJCOBO_01626 2.12e-222 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
HNMJCOBO_01627 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
HNMJCOBO_01628 3.29e-144 ccpN - - K - - - CBS domain
HNMJCOBO_01629 6.38e-191 yqfL 2.7.11.33, 2.7.4.28 - S ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HNMJCOBO_01630 6.03e-114 yqxD - - S ko:K09768 - ko00000 Belongs to the UPF0178 family
HNMJCOBO_01631 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HNMJCOBO_01632 2.79e-254 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HNMJCOBO_01633 1.61e-81 cccA - - C ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
HNMJCOBO_01634 9.8e-150 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
HNMJCOBO_01635 3.1e-268 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HNMJCOBO_01636 1.75e-226 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HNMJCOBO_01637 7.31e-52 yqfQ - - S - - - YqfQ-like protein
HNMJCOBO_01638 5.42e-311 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HNMJCOBO_01639 1.04e-214 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HNMJCOBO_01640 3.01e-49 yqfT - - S - - - Protein of unknown function (DUF2624)
HNMJCOBO_01641 3.83e-199 yqfU - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
HNMJCOBO_01642 8.59e-107 zur - - P ko:K02076 - ko00000,ko03000 Belongs to the Fur family
HNMJCOBO_01643 8.25e-142 yqfW - - S ko:K05967 - ko00000 Belongs to the 5'(3')-deoxyribonucleotidase family
HNMJCOBO_01644 2.04e-81 yqfX - - S - - - membrane
HNMJCOBO_01645 5.22e-257 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HNMJCOBO_01646 2.84e-63 yqfZ - - M ko:K06417 - ko00000 LysM domain
HNMJCOBO_01647 2.05e-99 yqgA - - - - - - -
HNMJCOBO_01648 9.27e-172 yqgB - - S - - - Protein of unknown function (DUF1189)
HNMJCOBO_01649 8.25e-101 yqgC - - S ko:K09793 - ko00000 protein conserved in bacteria
HNMJCOBO_01650 1.59e-148 sodA 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
HNMJCOBO_01651 3.96e-293 yqgE - - EGP ko:K08222 - ko00000,ko02000 Major facilitator superfamily
HNMJCOBO_01652 0.0 pbpA - - M ko:K21465,ko:K21466 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
HNMJCOBO_01653 4.51e-206 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
HNMJCOBO_01654 7.43e-205 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
HNMJCOBO_01655 1.47e-28 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
HNMJCOBO_01656 7.68e-161 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
HNMJCOBO_01657 2.4e-190 pstBA 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HNMJCOBO_01658 2.71e-187 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HNMJCOBO_01659 2.92e-98 yqzC - - S - - - YceG-like family
HNMJCOBO_01660 3.42e-68 yqzD - - - - - - -
HNMJCOBO_01662 1.24e-260 yqgM 2.4.1.250 - M ko:K15521 - ko00000,ko01000 Glycosyl transferases group 1
HNMJCOBO_01663 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
HNMJCOBO_01664 2.38e-138 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HNMJCOBO_01665 3.38e-14 yqgO - - - - - - -
HNMJCOBO_01666 0.0 gluP 3.4.21.105 - O ko:K19225 - ko00000,ko01000,ko01002 membrane protein (homolog of Drosophila rhomboid)
HNMJCOBO_01667 2.19e-44 yqgQ - - S - - - Protein conserved in bacteria
HNMJCOBO_01668 2.81e-231 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
HNMJCOBO_01669 0.0 yqgS 2.7.8.20 - M ko:K01138,ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
HNMJCOBO_01670 1.06e-283 yqgT 3.4.19.11 - E ko:K01308 - ko00000,ko01000,ko01002 Gamma-D-glutamyl-L-diamino acid endopeptidase
HNMJCOBO_01671 5.65e-258 yqgU - - - - - - -
HNMJCOBO_01672 7.34e-66 yqgV - - S - - - Thiamine-binding protein
HNMJCOBO_01673 1.91e-31 yqgW - - S - - - Protein of unknown function (DUF2759)
HNMJCOBO_01674 5.52e-158 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
HNMJCOBO_01675 1.46e-50 yqgY - - S - - - Protein of unknown function (DUF2626)
HNMJCOBO_01676 7.79e-85 yqgZ 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
HNMJCOBO_01678 1.06e-193 yqhA - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HNMJCOBO_01679 8.56e-307 yqhB - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
HNMJCOBO_01680 1.51e-233 yqxL - - P - - - Mg2 transporter protein
HNMJCOBO_01682 9.05e-257 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HNMJCOBO_01683 1.29e-220 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 COG1459 Type II secretory pathway, component PulF
HNMJCOBO_01684 5.33e-63 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
HNMJCOBO_01685 9.7e-94 gspH - - NU ko:K02246,ko:K02457,ko:K02459,ko:K02672,ko:K08084,ko:K10926 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02035,ko02044 protein transport across the cell outer membrane
HNMJCOBO_01686 4.35e-79 comGE - - - ko:K02247 - ko00000,ko00002,ko02044 -
HNMJCOBO_01687 3.44e-65 comGF - - U ko:K02246,ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
HNMJCOBO_01688 3.78e-57 - - - S ko:K02249 - ko00000,ko00002,ko02044 ComG operon protein 7
HNMJCOBO_01689 2.84e-36 yqzE - - S - - - YqzE-like protein
HNMJCOBO_01690 6.36e-71 yqzG - - S - - - Protein of unknown function (DUF3889)
HNMJCOBO_01691 1.61e-155 yqxM - - - ko:K19433 - ko00000 -
HNMJCOBO_01692 7.4e-98 sipW 3.4.21.89 - U ko:K13280 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase
HNMJCOBO_01693 1.49e-180 tasA_1 - - S ko:K06336 - ko00000,ko01002 Cell division protein FtsN
HNMJCOBO_01694 3.69e-72 sinR - - K ko:K19449 - ko00000,ko03000 transcriptional
HNMJCOBO_01695 4.84e-34 sinI - - S ko:K06372 - ko00000 Anti-repressor SinI
HNMJCOBO_01696 9.14e-197 yqhG - - S - - - Bacterial protein YqhG of unknown function
HNMJCOBO_01697 0.0 yqhH - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
HNMJCOBO_01698 1.57e-260 gcvT 2.1.2.10 - E ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
HNMJCOBO_01699 0.0 gcvPA 1.4.4.2 - E ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HNMJCOBO_01700 0.0 gcvPB 1.4.4.2 - E ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HNMJCOBO_01701 7.5e-83 yqhL - - P - - - COG0607 Rhodanese-related sulfurtransferase
HNMJCOBO_01702 9.17e-204 lipM 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
HNMJCOBO_01703 1.97e-97 mntR - - K ko:K03709 - ko00000,ko03000 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
HNMJCOBO_01704 1.21e-210 yqhO - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
HNMJCOBO_01705 5.18e-81 yqhP - - - - - - -
HNMJCOBO_01706 4.42e-222 yqhQ - - S - - - Protein of unknown function (DUF1385)
HNMJCOBO_01707 8.02e-121 yqhR - - S - - - Conserved membrane protein YqhR
HNMJCOBO_01708 1.17e-101 aroQ 4.2.1.10 - E ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a trans-dehydration via an enolate intermediate
HNMJCOBO_01709 3.65e-250 yqhT 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
HNMJCOBO_01710 4.8e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HNMJCOBO_01711 6.96e-50 yqhV - - S - - - Protein of unknown function (DUF2619)
HNMJCOBO_01712 1.22e-218 spoIIIAA - - S ko:K06390 - ko00000 stage III sporulation protein AA
HNMJCOBO_01713 6.93e-112 spoIIIAB - - S ko:K06391 - ko00000 Stage III sporulation protein
HNMJCOBO_01714 1.63e-39 spoIIIAC - - S ko:K06392 - ko00000 stage III sporulation protein AC
HNMJCOBO_01715 1.93e-77 spoIIIAD - - S ko:K06393 - ko00000 Stage III sporulation protein AD
HNMJCOBO_01716 7.65e-257 spoIIIAE - - S ko:K06394 - ko00000 stage III sporulation protein AE
HNMJCOBO_01717 1.28e-131 spoIIIAF - - S ko:K06395 - ko00000 Stage III sporulation protein AF (Spore_III_AF)
HNMJCOBO_01718 9.25e-150 spoIIIAG - - S ko:K06396 - ko00000 stage III sporulation protein AG
HNMJCOBO_01719 9.92e-135 spoIIIAH - - S ko:K06397 - ko00000 SpoIIIAH-like protein
HNMJCOBO_01720 3.21e-93 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HNMJCOBO_01721 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
HNMJCOBO_01722 1.65e-88 yqhY - - S - - - protein conserved in bacteria
HNMJCOBO_01723 4.8e-86 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HNMJCOBO_01724 1.07e-200 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HNMJCOBO_01725 3.55e-312 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HNMJCOBO_01726 1.09e-51 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HNMJCOBO_01727 4.2e-209 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
HNMJCOBO_01728 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HNMJCOBO_01729 1.77e-198 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 rRNA methylase
HNMJCOBO_01730 3.75e-103 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
HNMJCOBO_01731 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
HNMJCOBO_01732 1.26e-303 spoIVB 3.4.21.116 - M ko:K06399 - ko00000,ko01000,ko01002 Stage IV sporulation protein B
HNMJCOBO_01733 1.89e-186 spo0A - - KT ko:K07699 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
HNMJCOBO_01735 1.63e-272 yqiG - - C - - - COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
HNMJCOBO_01736 4.74e-37 - - - - - - - -
HNMJCOBO_01737 1.34e-137 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Cell wall hydrolase autolysin
HNMJCOBO_01738 7.42e-172 yqiK 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
HNMJCOBO_01739 1.91e-279 mmgA 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
HNMJCOBO_01740 5.91e-200 mmgB 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
HNMJCOBO_01741 1.73e-268 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
HNMJCOBO_01742 3.9e-266 mmgD 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
HNMJCOBO_01743 0.0 prpD 4.2.1.79 - S ko:K01720 ko00640,map00640 ko00000,ko00001,ko01000 2-methylcitrate dehydratase
HNMJCOBO_01744 7.23e-208 prpB 4.1.3.30, 5.4.2.9 - G ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HNMJCOBO_01745 1.19e-46 yqzF - - S - - - Protein of unknown function (DUF2627)
HNMJCOBO_01746 0.0 bkdR - - KT - - - Transcriptional regulator
HNMJCOBO_01747 1.74e-198 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 phosphate butyryltransferase
HNMJCOBO_01748 7.81e-262 ldh 1.4.1.9 - E ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
HNMJCOBO_01749 3.39e-255 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Belongs to the acetokinase family
HNMJCOBO_01750 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HNMJCOBO_01751 1.11e-237 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HNMJCOBO_01752 6.92e-235 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HNMJCOBO_01753 1.32e-288 bkdB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HNMJCOBO_01754 2.6e-194 - - - K ko:K19575 - ko00000,ko00002,ko03000 helix_turn_helix, mercury resistance
HNMJCOBO_01755 3.09e-267 norA - - EGP ko:K08153,ko:K19576,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
HNMJCOBO_01756 1.72e-213 bmrU - - I - - - COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HNMJCOBO_01757 3.79e-101 yqiW - - S - - - Belongs to the UPF0403 family
HNMJCOBO_01758 1.43e-175 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
HNMJCOBO_01759 8.94e-143 artQ - - E ko:K02029 - ko00000,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
HNMJCOBO_01760 5.2e-166 artM 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
HNMJCOBO_01761 1.55e-224 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
HNMJCOBO_01762 6.92e-128 yqjB - - S - - - protein conserved in bacteria
HNMJCOBO_01764 1.9e-94 mce 5.1.99.1 - E ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0346 Lactoylglutathione lyase and related lyases
HNMJCOBO_01765 0.0 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HNMJCOBO_01766 1.76e-257 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 COG2195 Di- and tripeptidases
HNMJCOBO_01767 8.77e-184 yqjF - - S ko:K09166 - ko00000 Uncharacterized conserved protein (COG2071)
HNMJCOBO_01768 3.36e-184 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HNMJCOBO_01769 1.77e-32 yqzJ - - - - - - -
HNMJCOBO_01770 7.8e-301 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HNMJCOBO_01771 0.0 gnd 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HNMJCOBO_01772 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HNMJCOBO_01773 2.2e-221 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HNMJCOBO_01774 8.59e-27 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
HNMJCOBO_01775 4.33e-185 yqjL - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HNMJCOBO_01776 1.72e-245 namA 1.6.99.1 - C ko:K00354 - ko00000,ko01000 Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
HNMJCOBO_01777 0.0 rocB - - E - - - arginine degradation protein
HNMJCOBO_01778 9.32e-188 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HNMJCOBO_01779 1.09e-227 yqjP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
HNMJCOBO_01780 6.89e-185 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
HNMJCOBO_01781 0.0 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
HNMJCOBO_01782 6.6e-229 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
HNMJCOBO_01783 2.21e-94 yqjT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HNMJCOBO_01785 8.91e-289 yqjV - - G - - - Major Facilitator Superfamily
HNMJCOBO_01787 2.43e-303 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HNMJCOBO_01788 3.23e-66 yqiX - - S - - - YolD-like protein
HNMJCOBO_01789 5.46e-113 yqjY - - K ko:K06977 - ko00000 acetyltransferase
HNMJCOBO_01790 5.51e-79 yqjZ - - S - - - enzyme involved in biosynthesis of extracellular polysaccharides
HNMJCOBO_01791 2.28e-248 yqkA - - K - - - GrpB protein
HNMJCOBO_01792 6.17e-73 yqkB - - S - - - Belongs to the HesB IscA family
HNMJCOBO_01793 1.12e-53 yqkC - - S - - - Protein of unknown function (DUF2552)
HNMJCOBO_01794 1.09e-220 yqkD - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
HNMJCOBO_01795 6.61e-26 yqkE - - S - - - Protein of unknown function (DUF3886)
HNMJCOBO_01796 1.26e-215 yqkF - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
HNMJCOBO_01797 8.21e-10 - - - S - - - Protein of unknown function (DUF3936)
HNMJCOBO_01798 4.07e-120 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
HNMJCOBO_01799 5.06e-281 yqxK - - L - - - DNA helicase
HNMJCOBO_01800 3.18e-77 ansR - - K - - - Transcriptional regulator
HNMJCOBO_01801 1.77e-238 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase
HNMJCOBO_01802 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Aspartate ammonia-lyase
HNMJCOBO_01803 0.0 mleN - - C ko:K03315 - ko00000,ko02000 Na H antiporter
HNMJCOBO_01804 3.95e-309 mleA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
HNMJCOBO_01805 1.72e-40 yqkK - - - - - - -
HNMJCOBO_01806 1.96e-139 spoIIM - - S ko:K06384 - ko00000 Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
HNMJCOBO_01807 2.26e-104 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
HNMJCOBO_01808 2.25e-49 - - - S - - - Protein of unknown function (DUF4227)
HNMJCOBO_01809 2.26e-213 xerD - - L ko:K04763 - ko00000,ko03036 recombinase XerD
HNMJCOBO_01810 2.77e-293 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
HNMJCOBO_01811 1.39e-190 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HNMJCOBO_01812 5.58e-270 dacF 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
HNMJCOBO_01813 1.98e-76 spoIIAA - - T ko:K06378 - ko00000 Belongs to the anti-sigma-factor antagonist family
HNMJCOBO_01814 1.37e-99 spoIIAB 2.7.11.1 - F ko:K06379 - ko00000,ko01000 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
HNMJCOBO_01815 1.18e-174 sigF - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HNMJCOBO_01816 6.68e-143 spoVAA - - S ko:K06403 - ko00000 Stage V sporulation protein AA
HNMJCOBO_01817 5.43e-90 spoVAB - - S ko:K06404 - ko00000 Stage V sporulation protein AB
HNMJCOBO_01818 6.71e-102 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
HNMJCOBO_01819 6.02e-246 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
HNMJCOBO_01820 2.15e-75 spoVAEB - - S ko:K06407 - ko00000 stage V sporulation protein
HNMJCOBO_01821 1.85e-143 - - - S ko:K06407 - ko00000 stage V sporulation protein
HNMJCOBO_01822 0.0 spoVAF - - EG ko:K06408 - ko00000 Stage V sporulation protein AF
HNMJCOBO_01823 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HNMJCOBO_01824 2.67e-193 ypuA - - S - - - Secreted protein
HNMJCOBO_01825 3.52e-105 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HNMJCOBO_01827 3.82e-09 - - - S - - - SNARE associated Golgi protein
HNMJCOBO_01828 4.06e-19 - - - S - - - SNARE associated Golgi protein
HNMJCOBO_01829 1.28e-45 ypzJ - - S ko:K07069 - ko00000 nucleic-acid-binding protein containing a Zn-ribbon domain
HNMJCOBO_01830 2.66e-122 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HNMJCOBO_01831 5.98e-72 ypuD - - - - - - -
HNMJCOBO_01832 7.21e-261 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HNMJCOBO_01833 1.24e-147 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
HNMJCOBO_01834 3.12e-292 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HNMJCOBO_01835 8.41e-107 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HNMJCOBO_01836 1.12e-83 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HNMJCOBO_01837 7.5e-122 ypuF - - S ko:K09763 - ko00000 Domain of unknown function (DUF309)
HNMJCOBO_01838 1.33e-167 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HNMJCOBO_01839 2e-135 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HNMJCOBO_01840 6.13e-128 ypuI - - S - - - Protein of unknown function (DUF3907)
HNMJCOBO_01841 1.18e-272 dacB 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
HNMJCOBO_01842 7.57e-135 spmA - - S ko:K06373 - ko00000 Spore maturation protein
HNMJCOBO_01843 8.62e-114 spmB - - S ko:K06374 - ko00000 Spore maturation protein
HNMJCOBO_01844 4.45e-169 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
HNMJCOBO_01845 1.5e-128 resA - - CO - - - Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
HNMJCOBO_01846 0.0 resB - - O ko:K07399 - ko00000 COG1333 ResB protein required for cytochrome c biosynthesis
HNMJCOBO_01847 4.48e-277 resC - - O - - - 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
HNMJCOBO_01848 1.69e-171 resD - - T ko:K07775 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HNMJCOBO_01849 0.0 resE 2.7.13.3 - T ko:K07651 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HNMJCOBO_01850 1.08e-133 sigX - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HNMJCOBO_01851 5.44e-257 rsiX - - - - - - -
HNMJCOBO_01852 2.89e-175 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HNMJCOBO_01853 0.0 serA 1.1.1.399, 1.1.1.95 - E ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HNMJCOBO_01854 3.07e-122 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HNMJCOBO_01855 8.35e-55 fer - - C ko:K05337 - ko00000 Ferredoxin
HNMJCOBO_01856 5.67e-258 ypbB 5.1.3.1 - S ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 protein conserved in bacteria
HNMJCOBO_01857 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
HNMJCOBO_01858 2.4e-126 ypbD - - S ko:K07052 - ko00000 metal-dependent membrane protease
HNMJCOBO_01859 1e-141 ypbE - - M - - - Lysin motif
HNMJCOBO_01860 1.66e-105 ypbF - - S - - - Protein of unknown function (DUF2663)
HNMJCOBO_01861 5.05e-187 ypbG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
HNMJCOBO_01862 5.56e-136 mecB - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HNMJCOBO_01863 1.66e-307 gudB 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
HNMJCOBO_01864 5.29e-224 ypdA 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 COG0492 Thioredoxin reductase
HNMJCOBO_01865 1.76e-153 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
HNMJCOBO_01866 1.63e-206 sleB 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Spore cortex-lytic enzyme
HNMJCOBO_01867 0.0 ypeB - - H ko:K06313 - ko00000 sporulation protein
HNMJCOBO_01868 1.42e-138 ypfA - - M - - - Flagellar protein YcgR
HNMJCOBO_01869 1.74e-32 - - - S - - - Family of unknown function (DUF5359)
HNMJCOBO_01870 2.36e-145 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
HNMJCOBO_01871 7.8e-262 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
HNMJCOBO_01872 1.14e-235 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HNMJCOBO_01873 1.13e-11 - - - S - - - YpzI-like protein
HNMJCOBO_01874 2.73e-134 yphA - - - - - - -
HNMJCOBO_01875 6.18e-207 yphB - - S ko:K05739 - ko00000 YIEGIA protein
HNMJCOBO_01876 8.69e-40 ypzH - - - - - - -
HNMJCOBO_01877 4.77e-316 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
HNMJCOBO_01878 4.05e-243 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
HNMJCOBO_01879 7.09e-27 yphE - - S - - - Protein of unknown function (DUF2768)
HNMJCOBO_01880 9.07e-178 yphF - - - - - - -
HNMJCOBO_01881 0.0 spoIVA - - S ko:K06398 - ko00000 ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HNMJCOBO_01882 1.07e-57 hbs - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HNMJCOBO_01883 4.41e-131 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
HNMJCOBO_01884 5.13e-46 mtrB - - K ko:K06285 - ko00000,ko03000 Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
HNMJCOBO_01885 8.72e-178 hepS 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
HNMJCOBO_01886 1.34e-169 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HNMJCOBO_01887 1.17e-248 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
HNMJCOBO_01888 3.08e-104 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
HNMJCOBO_01889 3.69e-183 cheR 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 COG1352 Methylase of chemotaxis methyl-accepting proteins
HNMJCOBO_01890 1.44e-277 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HNMJCOBO_01891 3.17e-260 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HNMJCOBO_01892 9.82e-84 aroH 5.4.99.5 - E ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
HNMJCOBO_01893 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HNMJCOBO_01894 2.03e-228 trpD 2.4.2.18, 4.1.3.27 - E ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HNMJCOBO_01895 1.25e-146 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
HNMJCOBO_01896 2.71e-151 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
HNMJCOBO_01897 3.8e-294 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HNMJCOBO_01898 2.21e-185 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HNMJCOBO_01899 1.06e-257 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HNMJCOBO_01900 1.71e-264 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
HNMJCOBO_01901 9.91e-302 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HNMJCOBO_01902 1.06e-298 ypiA - - S - - - COG0457 FOG TPR repeat
HNMJCOBO_01903 7.45e-129 ypiB - - S - - - Belongs to the UPF0302 family
HNMJCOBO_01904 9.21e-99 ypiF - - S - - - Protein of unknown function (DUF2487)
HNMJCOBO_01905 3.35e-126 qcrA - - C ko:K03886 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Menaquinol-cytochrome c reductase
HNMJCOBO_01906 8.76e-166 qcrB - - C ko:K03887 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG1290 Cytochrome b subunit of the bc complex
HNMJCOBO_01907 5.71e-191 qcrC - - C ko:K03888 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Menaquinol-cytochrome c reductase cytochrome b c subunit
HNMJCOBO_01908 2.82e-126 ypjA - - S - - - membrane
HNMJCOBO_01909 9.32e-181 ypjB - - S - - - sporulation protein
HNMJCOBO_01910 3.7e-200 ypjC - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
HNMJCOBO_01911 1.01e-73 ypjD - - S - - - Nucleotide pyrophosphohydrolase
HNMJCOBO_01912 2.4e-189 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HNMJCOBO_01913 2.52e-93 mgsA 4.2.3.3 - G ko:K01734 ko00640,ko01120,map00640,map01120 ko00000,ko00001,ko01000 methylglyoxal synthase
HNMJCOBO_01914 1.89e-166 bshB1 - - S ko:K01463 - ko00000,ko01000 proteins, LmbE homologs
HNMJCOBO_01915 1.72e-267 bshA - GT4 M ko:K00754 - ko00000,ko01000 N-acetyl-alpha-D-glucosaminyl L-malate synthase
HNMJCOBO_01916 2.14e-278 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HNMJCOBO_01917 5.68e-233 birA 6.3.4.15 - K ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HNMJCOBO_01918 4.85e-194 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
HNMJCOBO_01919 1.83e-198 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HNMJCOBO_01920 4.16e-85 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HNMJCOBO_01921 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
HNMJCOBO_01922 1.52e-32 ypmA - - S - - - Protein of unknown function (DUF4264)
HNMJCOBO_01923 2.27e-103 ypmB - - S - - - protein conserved in bacteria
HNMJCOBO_01924 4.37e-285 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
HNMJCOBO_01925 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 asparaginyl-tRNA
HNMJCOBO_01926 6.62e-165 dnaD - - L ko:K02086 - ko00000 DNA replication protein DnaD
HNMJCOBO_01927 3.57e-158 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HNMJCOBO_01928 1.43e-121 ypoC - - - - - - -
HNMJCOBO_01929 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
HNMJCOBO_01930 3.2e-150 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HNMJCOBO_01931 4.54e-241 yppC - - S - - - Protein of unknown function (DUF2515)
HNMJCOBO_01934 7.9e-10 yppE - - S - - - Bacterial domain of unknown function (DUF1798)
HNMJCOBO_01935 9.21e-11 - - - S - - - YppF-like protein
HNMJCOBO_01936 8.72e-68 yppG - - S - - - YppG-like protein
HNMJCOBO_01937 4.33e-95 hspX - - O ko:K06335,ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
HNMJCOBO_01938 2.34e-113 ypqE - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 COG2190 Phosphotransferase system IIA components
HNMJCOBO_01939 0.0 yprA - - L ko:K06877 - ko00000 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
HNMJCOBO_01940 7.21e-301 yprB - - L ko:K07502 - ko00000 RNase_H superfamily
HNMJCOBO_01941 3.41e-130 ypsA - - S - - - Belongs to the UPF0398 family
HNMJCOBO_01942 2.97e-60 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HNMJCOBO_01943 1.43e-276 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
HNMJCOBO_01944 9.72e-66 yqgA - - - - - - -
HNMJCOBO_01946 0.0 ypvA 3.6.4.12 - KL ko:K03722 - ko00000,ko01000,ko03400 COG1199 Rad3-related DNA helicases
HNMJCOBO_01947 1.88e-175 kduD 1.1.1.127 - IQ ko:K00065 ko00040,map00040 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HNMJCOBO_01948 1.2e-202 kduI 5.3.1.17 - G ko:K01815 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
HNMJCOBO_01949 1.84e-236 kdgR - - K ko:K02525 - ko00000,ko03000 transcriptional
HNMJCOBO_01950 2.83e-237 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0524 Sugar kinases, ribokinase family
HNMJCOBO_01951 1.47e-132 kdgA 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 2-dehydro-3-deoxy-phosphogluconate aldolase
HNMJCOBO_01952 5.8e-224 kdgT - - P ko:K02526 - ko00000,ko02000 The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
HNMJCOBO_01953 0.0 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HNMJCOBO_01954 8.16e-129 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HNMJCOBO_01955 3.14e-294 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
HNMJCOBO_01956 4.55e-266 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
HNMJCOBO_01957 3.33e-113 ypbQ - - S ko:K16168 - ko00000,ko01008 protein conserved in bacteria
HNMJCOBO_01958 0.0 ypbR - - S - - - Dynamin family
HNMJCOBO_01959 4.07e-52 ypbS - - S - - - Protein of unknown function (DUF2533)
HNMJCOBO_01960 1.08e-11 - - - - - - - -
HNMJCOBO_01961 2.26e-213 ypcP - - L - - - 5'3' exonuclease
HNMJCOBO_01962 5.23e-05 - - - - ko:K06429 - ko00000 -
HNMJCOBO_01963 1.27e-86 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease
HNMJCOBO_01964 2.68e-135 ypdP - - S ko:K09125 - ko00000 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HNMJCOBO_01965 1.9e-161 ypeP 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 COG0328 Ribonuclease HI
HNMJCOBO_01966 7.99e-41 ypeQ - - S - - - Zinc-finger
HNMJCOBO_01967 1.05e-40 - - - S - - - Protein of unknown function (DUF2564)
HNMJCOBO_01968 1.17e-22 degR - - - - - - -
HNMJCOBO_01969 2.54e-42 cspD - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
HNMJCOBO_01970 1.28e-276 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
HNMJCOBO_01971 1.49e-225 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HNMJCOBO_01972 5.41e-115 bsaA 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
HNMJCOBO_01973 3.15e-26 yagB - - S ko:K06950 - ko00000 phosphohydrolase
HNMJCOBO_01974 5.04e-65 yagB - - S ko:K06950 - ko00000 phosphohydrolase
HNMJCOBO_01975 9.9e-205 ypgR - - C - - - COG0694 Thioredoxin-like proteins and domains
HNMJCOBO_01976 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
HNMJCOBO_01977 9.69e-99 yphP - - S - - - Belongs to the UPF0403 family
HNMJCOBO_01978 8.04e-183 ypiP - - AJ - - - Putative SAM-dependent methyltransferase
HNMJCOBO_01979 3.47e-148 ypjP - - S - - - YpjP-like protein
HNMJCOBO_01980 8.91e-121 ltrC 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
HNMJCOBO_01981 1.21e-201 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HNMJCOBO_01982 9.96e-124 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HNMJCOBO_01983 1.71e-145 ypkP 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HNMJCOBO_01984 8.03e-143 yplQ - - S ko:K11068 - ko00000,ko02042 protein, Hemolysin III
HNMJCOBO_01985 1.4e-236 yplP - - K - - - Transcriptional regulator
HNMJCOBO_01986 3.64e-310 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HNMJCOBO_01987 1.28e-54 ypmP - - S - - - Protein of unknown function (DUF2535)
HNMJCOBO_01988 3.23e-139 ypmQ - - S ko:K07152 - ko00000,ko03029 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
HNMJCOBO_01989 1.28e-178 ypmR - - E - - - GDSL-like Lipase/Acylhydrolase
HNMJCOBO_01990 1.95e-128 ypmS - - S - - - protein conserved in bacteria
HNMJCOBO_01991 2.13e-40 ypmT - - S - - - Uncharacterized ympT
HNMJCOBO_01992 3.49e-290 mepA - - V - - - MATE efflux family protein
HNMJCOBO_01993 4.14e-94 ypoP - - K - - - transcriptional
HNMJCOBO_01994 8.41e-134 msrB 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HNMJCOBO_01995 3.52e-105 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
HNMJCOBO_01996 1.76e-124 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
HNMJCOBO_01997 1.31e-303 yokA - - L - - - Recombinase
HNMJCOBO_01999 7.89e-105 - - - S ko:K03824 - ko00000,ko01000 family acetyltransferase
HNMJCOBO_02000 1.94e-166 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
HNMJCOBO_02002 4.55e-178 - - - S - - - Protein of unknown function (DUF4238)
HNMJCOBO_02003 2.12e-83 - - - G - - - SMI1-KNR4 cell-wall
HNMJCOBO_02004 1.53e-154 - - - V - - - HNH endonuclease
HNMJCOBO_02005 0.0 - - - UW ko:K21487,ko:K21489,ko:K21491,ko:K21493 - ko00000,ko01000,ko02048 nuclease activity
HNMJCOBO_02006 9.26e-123 - - - S ko:K21490 - ko00000,ko02048 SMI1 / KNR4 family (SUKH-1)
HNMJCOBO_02007 7.64e-142 yokK - - S - - - SMI1 / KNR4 family
HNMJCOBO_02008 3.7e-128 - - - J - - - Acetyltransferase (GNAT) domain
HNMJCOBO_02012 1.42e-55 - - - - - - - -
HNMJCOBO_02013 4.82e-67 - - - S - - - YolD-like protein
HNMJCOBO_02014 2.92e-297 - - - S - - - damaged DNA binding
HNMJCOBO_02016 8.21e-99 - - - T - - - Adenylate and Guanylate cyclase catalytic domain
HNMJCOBO_02018 7.88e-135 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
HNMJCOBO_02019 4.83e-50 - - - S - - - Bacteriophage holin
HNMJCOBO_02021 1.35e-92 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
HNMJCOBO_02022 4.61e-283 - - - M - - - Pectate lyase superfamily protein
HNMJCOBO_02023 9.78e-170 - - - - - - - -
HNMJCOBO_02024 0.0 - - - S - - - Pfam Transposase IS66
HNMJCOBO_02025 2.16e-109 - - - S - - - Phage tail protein
HNMJCOBO_02026 0.0 - - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HNMJCOBO_02027 2.37e-151 - - - - - - - -
HNMJCOBO_02031 9.16e-121 - - - - - - - -
HNMJCOBO_02033 1.47e-152 - - - L - - - Belongs to the 'phage' integrase family
HNMJCOBO_02034 2.82e-85 - - - - - - - -
HNMJCOBO_02035 6.47e-110 - - - - - - - -
HNMJCOBO_02036 5.57e-127 - 3.1.4.46, 5.4.2.11 - C ko:K01126,ko:K01834 ko00010,ko00260,ko00564,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00564,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 glycerophosphoryl diester phosphodiesterase
HNMJCOBO_02039 5.08e-28 - - - - - - - -
HNMJCOBO_02040 3.38e-60 - - - - - - - -
HNMJCOBO_02043 2.14e-143 - - - - - - - -
HNMJCOBO_02044 1.97e-168 - - - - - - - -
HNMJCOBO_02045 3.61e-117 - - - - - - - -
HNMJCOBO_02046 3.86e-156 - - - - - - - -
HNMJCOBO_02048 8.95e-91 - - - - - - - -
HNMJCOBO_02049 2.31e-105 - - - - - - - -
HNMJCOBO_02050 3.43e-236 - - - - - - - -
HNMJCOBO_02051 7.15e-122 - - - - - - - -
HNMJCOBO_02052 0.0 - - - - - - - -
HNMJCOBO_02053 0.0 - - - - - - - -
HNMJCOBO_02054 0.0 - - - S - - - Terminase-like family
HNMJCOBO_02055 4.45e-225 - - - - - - - -
HNMJCOBO_02058 7.34e-290 - - - - - - - -
HNMJCOBO_02060 1.21e-54 - - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HNMJCOBO_02061 0.0 - - - - - - - -
HNMJCOBO_02065 6.85e-295 - - - S - - - DNA replication origin binding
HNMJCOBO_02079 2.04e-06 - - - - - - - -
HNMJCOBO_02084 1.79e-39 - - - - - - - -
HNMJCOBO_02088 4.45e-91 - - - - - - - -
HNMJCOBO_02094 3.55e-312 - - - - - - - -
HNMJCOBO_02107 3.86e-21 - - - S - - - Protein of unknown function (DUF1273)
HNMJCOBO_02108 8.07e-100 - - - S - - - Protein of unknown function (DUF1273)
HNMJCOBO_02110 2.75e-51 - - - - - - - -
HNMJCOBO_02118 1.23e-188 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 - L ko:K01971,ko:K10747 ko03030,ko03410,ko03420,ko03430,ko03450,map03030,map03410,map03420,map03430,map03450 ko00000,ko00001,ko01000,ko03032,ko03400 ATP-dependent DNA ligase
HNMJCOBO_02119 3.43e-163 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
HNMJCOBO_02122 2.5e-131 - - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
HNMJCOBO_02127 5.4e-200 - - - - - - - -
HNMJCOBO_02128 6.35e-229 - - - L - - - AAA domain
HNMJCOBO_02129 1.5e-110 - - - - - - - -
HNMJCOBO_02130 0.0 - - - J - - - DnaB-like helicase C terminal domain
HNMJCOBO_02131 5.05e-281 - - - L - - - DNA primase activity
HNMJCOBO_02132 0.0 - - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
HNMJCOBO_02133 0.0 - 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
HNMJCOBO_02134 4.1e-28 - - - S - - - protein conserved in bacteria
HNMJCOBO_02137 1.52e-103 tmk 2.1.1.45, 2.7.4.9 - F ko:K00560,ko:K00943 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 dTDP biosynthetic process
HNMJCOBO_02140 4.11e-86 - - - L - - - DNA methylase
HNMJCOBO_02145 2.66e-55 - - - M - - - self proteolysis
HNMJCOBO_02150 4.09e-28 - - - - - - - -
HNMJCOBO_02152 2.6e-10 - - - S - - - Protein of unknown function (DUF1653)
HNMJCOBO_02157 3.12e-82 - - - S - - - NrdI Flavodoxin like
HNMJCOBO_02158 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HNMJCOBO_02160 8.39e-231 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HNMJCOBO_02161 2.65e-48 - - - O - - - Glutaredoxin
HNMJCOBO_02163 2.11e-97 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
HNMJCOBO_02164 9.64e-21 XK27_09885 - - V - - - COG4767 Glycopeptide antibiotics resistance protein
HNMJCOBO_02166 8.84e-207 - - - S - - - Thymidylate synthase
HNMJCOBO_02167 6.81e-80 - - - - - - - -
HNMJCOBO_02171 7.46e-80 - - - - - - - -
HNMJCOBO_02174 2.24e-41 - - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
HNMJCOBO_02175 2.26e-207 - - - S - - - Calcineurin-like phosphoesterase
HNMJCOBO_02184 2.97e-134 - - - L - - - Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HNMJCOBO_02186 3.16e-82 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
HNMJCOBO_02187 4.17e-282 phy 3.1.3.8 - I ko:K01083 ko00562,map00562 ko00000,ko00001,ko01000 Myo-inositol-hexaphosphate 3-phosphohydrolase
HNMJCOBO_02188 2.95e-240 cgeB - - S ko:K06320 - ko00000 Spore maturation protein
HNMJCOBO_02189 5.57e-86 cgeA - - - ko:K06319 - ko00000 -
HNMJCOBO_02190 3.04e-59 cgeC - - - ko:K06321 - ko00000 -
HNMJCOBO_02191 0.0 cgeD - - M ko:K06322 - ko00000 maturation of the outermost layer of the spore
HNMJCOBO_02192 2.06e-186 yiiD - - K ko:K06323 - ko00000 acetyltransferase
HNMJCOBO_02194 0.0 yodT - - H - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HNMJCOBO_02196 9.44e-153 atoA 2.8.3.8, 2.8.3.9 - I ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HNMJCOBO_02197 0.0 yodQ 3.5.1.16, 3.5.1.18 - E ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetylornithine deacetylase
HNMJCOBO_02198 9.5e-200 yodP 2.3.1.264 - K ko:K21935 - ko00000,ko01000 Acetyltransferase (GNAT) family
HNMJCOBO_02199 0.0 kamA 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 lysine 2,3-aminomutase
HNMJCOBO_02200 3.44e-63 yokU - - S - - - YokU-like protein, putative antitoxin
HNMJCOBO_02201 7.3e-50 yozE - - S - - - Belongs to the UPF0346 family
HNMJCOBO_02202 3.84e-161 yodN - - - - - - -
HNMJCOBO_02204 5.18e-34 yozD - - S - - - YozD-like protein
HNMJCOBO_02205 4.02e-138 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
HNMJCOBO_02206 1.17e-71 yodL - - S - - - YodL-like
HNMJCOBO_02207 2.08e-12 - - - - - - - -
HNMJCOBO_02208 1.19e-163 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
HNMJCOBO_02209 1.33e-189 yodJ 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
HNMJCOBO_02210 4.86e-41 yodI - - - - - - -
HNMJCOBO_02211 3.03e-166 yodH - - Q - - - Methyltransferase
HNMJCOBO_02212 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
HNMJCOBO_02213 0.0 yodF - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HNMJCOBO_02214 2.36e-38 - - - S - - - Protein of unknown function (DUF3311)
HNMJCOBO_02215 1.96e-222 yodE - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
HNMJCOBO_02216 3.76e-146 yahD - - S ko:K06999 - ko00000 Carboxylesterase
HNMJCOBO_02217 1.11e-139 yodC - - C - - - nitroreductase
HNMJCOBO_02218 2.63e-73 yodB - - K - - - transcriptional
HNMJCOBO_02219 5.64e-84 iolK - - S - - - tautomerase
HNMJCOBO_02220 2.53e-287 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
HNMJCOBO_02221 5.59e-14 - - - - - - - -
HNMJCOBO_02222 2.88e-103 yozR - - S - - - COG0071 Molecular chaperone (small heat shock protein)
HNMJCOBO_02223 2.23e-205 rarD - - S ko:K05786 - ko00000,ko02000 -transporter
HNMJCOBO_02224 6.21e-57 - - - - - - - -
HNMJCOBO_02225 2.32e-79 yojF - - S - - - Protein of unknown function (DUF1806)
HNMJCOBO_02226 3.71e-161 yojG - - S ko:K22135 - ko00000,ko01000 deacetylase
HNMJCOBO_02227 1.18e-192 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HNMJCOBO_02228 6.88e-312 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
HNMJCOBO_02230 4.31e-141 dacB 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HNMJCOBO_02231 2.29e-293 yojK - - CG - - - UDP-glucoronosyl and UDP-glucosyl transferase
HNMJCOBO_02232 2.62e-267 - - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
HNMJCOBO_02233 8.54e-141 sodC 1.15.1.1 - P ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HNMJCOBO_02234 1.33e-207 yojN - - S ko:K04748 - ko00000 ATPase family associated with various cellular activities (AAA)
HNMJCOBO_02235 0.0 yojO - - P - - - Von Willebrand factor
HNMJCOBO_02236 0.0 odhA 1.2.4.2 - C ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
HNMJCOBO_02237 2.48e-262 odhB 2.3.1.61 - C ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
HNMJCOBO_02238 4.7e-214 yocS - - S ko:K03453 - ko00000 -transporter
HNMJCOBO_02239 8.78e-300 yocR - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HNMJCOBO_02240 2.26e-210 sodF 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Superoxide dismutase
HNMJCOBO_02241 0.0 sqhC 4.2.1.137 - I ko:K18115 - ko00000,ko01000 COG1657 Squalene cyclase
HNMJCOBO_02242 0.0 dhaS 1.2.1.3, 1.2.1.39 - C ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
HNMJCOBO_02243 1.91e-42 yozC - - - - - - -
HNMJCOBO_02244 2.17e-74 yozO - - S - - - Bacterial PH domain
HNMJCOBO_02245 1.83e-49 yocN - - - - - - -
HNMJCOBO_02246 2.94e-55 yozN - - - - - - -
HNMJCOBO_02247 6.6e-115 yocM - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
HNMJCOBO_02248 7.29e-46 - - - - - - - -
HNMJCOBO_02249 3.02e-70 yocL - - - - - - -
HNMJCOBO_02250 1.42e-107 yocK - - T - - - general stress protein
HNMJCOBO_02251 1.46e-147 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HNMJCOBO_02252 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
HNMJCOBO_02253 2.89e-175 yocH - - M - - - COG1388 FOG LysM repeat
HNMJCOBO_02254 4.71e-135 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HNMJCOBO_02255 1.22e-252 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HNMJCOBO_02256 3.99e-258 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
HNMJCOBO_02257 1.21e-243 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 peptidase S66
HNMJCOBO_02258 1.32e-122 yocC - - - - - - -
HNMJCOBO_02259 4.49e-186 - - - - - - - -
HNMJCOBO_02260 3.97e-119 yozB - - S ko:K08976 - ko00000 membrane
HNMJCOBO_02261 3.28e-157 yocA - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HNMJCOBO_02262 8.12e-69 czrA - - K ko:K22043 - ko00000,ko03000 transcriptional
HNMJCOBO_02263 7.69e-123 yobW - - - - - - -
HNMJCOBO_02264 2.05e-229 yobV - - K - - - WYL domain
HNMJCOBO_02265 1.55e-114 - - - K - - - Bacterial transcription activator, effector binding domain
HNMJCOBO_02266 1.34e-169 yobT - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
HNMJCOBO_02267 9.22e-129 yobS - - K - - - Transcriptional regulator
HNMJCOBO_02268 1.29e-183 - - - J - - - FR47-like protein
HNMJCOBO_02269 5.23e-175 yobQ - - K - - - helix_turn_helix, arabinose operon control protein
HNMJCOBO_02270 2.21e-72 csaA - - J ko:K06878 - ko00000 tRNA-binding protein
HNMJCOBO_02271 0.0 yobO - - M - - - Pectate lyase superfamily protein
HNMJCOBO_02272 0.0 iaaM 1.4.3.4 - E ko:K00274 ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034 ko00000,ko00001,ko00002,ko01000 COG1231 Monoamine oxidase
HNMJCOBO_02273 4.3e-136 yokH - - G - - - SMI1 / KNR4 family
HNMJCOBO_02274 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HNMJCOBO_02275 6.69e-112 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
HNMJCOBO_02276 3.58e-202 - - - - - - - -
HNMJCOBO_02277 0.0 - - - K - - - Psort location Cytoplasmic, score
HNMJCOBO_02278 2.08e-64 - - - - - - - -
HNMJCOBO_02279 2.05e-51 - - - S - - - YolD-like protein
HNMJCOBO_02280 1.52e-79 dinB2 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HNMJCOBO_02281 6.17e-158 dinB2 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HNMJCOBO_02283 6.23e-267 - - - S ko:K06369 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
HNMJCOBO_02287 1.36e-08 - - - - - - - -
HNMJCOBO_02288 6.85e-229 - - - - - - - -
HNMJCOBO_02289 1.92e-162 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
HNMJCOBO_02290 1.21e-90 yoaQ - - S - - - Evidence 4 Homologs of previously reported genes of
HNMJCOBO_02292 3.92e-76 - - - K - - - Helix-turn-helix
HNMJCOBO_02293 6.27e-51 - - - S - - - TM2 domain
HNMJCOBO_02294 1.3e-157 xlnB 3.2.1.8 - G ko:K01181 - ko00000,ko01000 Glycosyl hydrolases family 11
HNMJCOBO_02295 0.0 pps 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
HNMJCOBO_02299 1.41e-212 penP 3.5.2.6 - V ko:K17836,ko:K18766 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 beta-lactamase
HNMJCOBO_02300 6.18e-150 lin0465 - - S - - - DJ-1/PfpI family
HNMJCOBO_02301 5.63e-102 yoaW - - - - - - -
HNMJCOBO_02302 1.83e-201 yoaV - - EG - - - EamA-like transporter family
HNMJCOBO_02303 1.11e-201 yoaU - - K - - - LysR substrate binding domain
HNMJCOBO_02304 5.46e-189 yoaT - - S - - - Protein of unknown function (DUF817)
HNMJCOBO_02305 7.38e-50 yozG - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
HNMJCOBO_02306 1.6e-98 yoaS - - S - - - Protein of unknown function (DUF2975)
HNMJCOBO_02307 3.63e-218 yoaR - - V - - - vancomycin resistance protein
HNMJCOBO_02308 2.36e-116 - - - - - - - -
HNMJCOBO_02309 7.38e-88 yoaQ - - S - - - Evidence 4 Homologs of previously reported genes of
HNMJCOBO_02310 9.48e-188 yoaP - - K - - - YoaP-like
HNMJCOBO_02312 1.95e-296 oxdD 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
HNMJCOBO_02314 2.07e-170 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
HNMJCOBO_02315 5e-253 - 4.2.2.10 - G ko:K01732 - ko00000,ko01000 Amb_all
HNMJCOBO_02316 1.79e-145 yoaK - - S - - - Membrane
HNMJCOBO_02317 2.61e-171 yoaJ - - G ko:K20628 - ko00000 Endoglucanase C-terminal domain subunit and related proteins
HNMJCOBO_02318 0.0 yoaI 1.14.14.9 - Q ko:K00483 ko00350,ko01120,ko01220,map00350,map01120,map01220 ko00000,ko00001,ko01000 COG2368 Aromatic ring hydroxylase
HNMJCOBO_02319 0.0 yoaH - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 methyl-accepting chemotaxis protein
HNMJCOBO_02320 8.23e-62 - - - S - - - Protein of unknown function (DUF4025)
HNMJCOBO_02322 2.08e-44 yoaF - - - - - - -
HNMJCOBO_02323 0.0 yoaE - - C - - - belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HNMJCOBO_02324 4.27e-237 yoaD 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HNMJCOBO_02325 0.0 lsrK 2.7.1.189 - G ko:K11216 ko02024,map02024 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
HNMJCOBO_02326 1.11e-300 yoaB - - EGP - - - the major facilitator superfamily
HNMJCOBO_02327 5.91e-125 yoaA 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HNMJCOBO_02328 1.34e-185 yoxB - - - - - - -
HNMJCOBO_02329 8.39e-57 yoxC - - S - - - Bacterial protein of unknown function (DUF948)
HNMJCOBO_02330 7.94e-160 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
HNMJCOBO_02331 5.37e-79 rtp - - K - - - Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
HNMJCOBO_02332 2.72e-185 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HNMJCOBO_02333 8.13e-263 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HNMJCOBO_02334 2.61e-205 gltC - - K ko:K09681 - ko00000,ko03000 Transcriptional regulator
HNMJCOBO_02335 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
HNMJCOBO_02336 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
HNMJCOBO_02337 7.23e-238 yogA - - C ko:K13955 - ko00000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
HNMJCOBO_02338 1.3e-202 gltR1 - - K ko:K21959 - ko00000,ko03000 Transcriptional regulator
HNMJCOBO_02339 0.0 ggt 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
HNMJCOBO_02340 3.31e-47 yoeD - - G - - - Helix-turn-helix domain
HNMJCOBO_02341 1.14e-124 - - - L - - - Integrase
HNMJCOBO_02343 7.14e-128 yoeB - - S - - - IseA DL-endopeptidase inhibitor
HNMJCOBO_02344 9.8e-313 yoeA - - V - - - MATE efflux family protein
HNMJCOBO_02345 7.83e-240 yoxA 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
HNMJCOBO_02346 0.0 dacC 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
HNMJCOBO_02348 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HNMJCOBO_02349 0.0 - - - Q ko:K15665 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HNMJCOBO_02350 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HNMJCOBO_02351 1.59e-87 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HNMJCOBO_02352 6.84e-60 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HNMJCOBO_02353 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HNMJCOBO_02354 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HNMJCOBO_02355 0.0 - 6.3.2.14 - Q ko:K02364,ko:K15656,ko:K15668 ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024 ko00000,ko00001,ko01000,ko01008 amino acid activation for nonribosomal peptide biosynthetic process
HNMJCOBO_02356 2.12e-84 yngL - - S - - - Protein of unknown function (DUF1360)
HNMJCOBO_02357 0.0 yngK - - T - - - Glycosyl hydrolase-like 10
HNMJCOBO_02358 4.3e-41 - - - S - - - Family of unknown function (DUF5367)
HNMJCOBO_02359 1.31e-268 yngJ 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
HNMJCOBO_02360 0.0 yngI - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HNMJCOBO_02361 0.0 yngH 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
HNMJCOBO_02362 2.4e-41 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin carboxyl carrier protein
HNMJCOBO_02363 1.36e-211 yngG 4.1.3.4 - E ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA lyase
HNMJCOBO_02364 1.22e-174 yngF - - I - - - Belongs to the enoyl-CoA hydratase isomerase family
HNMJCOBO_02365 0.0 yngE - - I - - - COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HNMJCOBO_02366 9e-297 yngD - - S ko:K07097 - ko00000 phosphohydrolase (DHH superfamily)
HNMJCOBO_02367 8.18e-134 yngC - - S - - - membrane-associated protein
HNMJCOBO_02368 4.54e-209 yngB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
HNMJCOBO_02369 9.97e-103 yngA - - S - - - membrane
HNMJCOBO_02370 0.0 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
HNMJCOBO_02371 0.0 ynfF 3.2.1.136 GH5 M ko:K15924 - ko00000,ko01000 Belongs to the glycosyl hydrolase 30 family
HNMJCOBO_02373 0.0 bglC5 3.2.1.4 GH5,GH9 G ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 PFAM glycoside hydrolase family 5
HNMJCOBO_02374 0.0 alsT - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
HNMJCOBO_02375 1.06e-75 ynfC - - - - - - -
HNMJCOBO_02376 1.82e-18 - - - - - - - -
HNMJCOBO_02377 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HNMJCOBO_02378 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HNMJCOBO_02379 1.21e-90 yneT - - S ko:K06929 - ko00000 CoA-binding protein
HNMJCOBO_02380 5.48e-122 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HNMJCOBO_02381 8.97e-65 yneR - - S - - - Belongs to the HesB IscA family
HNMJCOBO_02382 1.63e-71 yneQ - - - - - - -
HNMJCOBO_02383 1.4e-95 yneP - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
HNMJCOBO_02384 6.62e-48 tlp - - S ko:K06434 - ko00000 Belongs to the Tlp family
HNMJCOBO_02386 9.26e-10 - - - S - - - Fur-regulated basic protein B
HNMJCOBO_02387 3.74e-120 yneN - - CO - - - alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HNMJCOBO_02388 0.0 citB 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HNMJCOBO_02389 3.75e-21 sspO - - S ko:K06432 - ko00000 Belongs to the SspO family
HNMJCOBO_02390 5.65e-27 sspP - - S ko:K06433 - ko00000 Belongs to the SspP family
HNMJCOBO_02391 5.77e-85 cotM - - O ko:K06335 - ko00000 Spore coat protein
HNMJCOBO_02392 2.79e-97 yneK - - S - - - Protein of unknown function (DUF2621)
HNMJCOBO_02393 2.51e-98 yneJ - - O - - - COG4846 Membrane protein involved in cytochrome C biogenesis
HNMJCOBO_02394 7.38e-78 ccdB - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 cheY-homologous receiver domain
HNMJCOBO_02395 4.13e-165 ccdA - - O ko:K06196 - ko00000,ko02000 cytochrome c biogenesis protein
HNMJCOBO_02396 4.59e-21 ynzD - - S - - - Spo0E like sporulation regulatory protein
HNMJCOBO_02397 4.36e-39 yneF - - S ko:K09976 - ko00000 UPF0154 protein
HNMJCOBO_02398 2.18e-106 yneE - - S - - - Sporulation inhibitor of replication protein sirA
HNMJCOBO_02399 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HNMJCOBO_02400 1.15e-43 ynzC - - S - - - UPF0291 protein
HNMJCOBO_02401 2.29e-144 yneB - - L - - - resolvase
HNMJCOBO_02402 8.5e-65 yneA - - D - - - Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
HNMJCOBO_02403 7.22e-142 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HNMJCOBO_02404 4.44e-104 fosB - - H ko:K11210,ko:K21252 - ko00000,ko01000,ko01504 Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
HNMJCOBO_02405 1.32e-96 yndM - - S - - - Protein of unknown function (DUF2512)
HNMJCOBO_02406 9.34e-175 yndL - - S - - - Replication protein
HNMJCOBO_02408 0.0 yndJ - - S - - - YndJ-like protein
HNMJCOBO_02409 3.46e-149 - - - S - - - Domain of unknown function (DUF4166)
HNMJCOBO_02410 9.15e-199 yndG - - S - - - DoxX-like family
HNMJCOBO_02411 9.64e-290 - - - S ko:K06293,ko:K06312 - ko00000 Spore germination protein
HNMJCOBO_02412 1.95e-250 yndE7 - - U ko:K06311 - ko00000,ko02000 Spore germination
HNMJCOBO_02413 0.0 yndD1 - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
HNMJCOBO_02416 4.32e-27 yndB - - S - - - Activator of Hsp90 ATPase homolog 1-like protein
HNMJCOBO_02417 8.92e-96 - - - - - - - -
HNMJCOBO_02418 2.37e-34 tatA - - U ko:K03116,ko:K03117,ko:K03646 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02000,ko02044 protein secretion
HNMJCOBO_02421 2.11e-170 - - - S - - - Domain of unknown function, YrpD
HNMJCOBO_02423 3.75e-208 - - - S - - - Thymidylate synthase
HNMJCOBO_02426 7.54e-22 - - - - - - - -
HNMJCOBO_02427 3.01e-102 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
HNMJCOBO_02428 3.44e-110 - - - S - - - Protein of unknown function (DUF2691)
HNMJCOBO_02429 3.05e-281 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HNMJCOBO_02430 3.64e-313 - - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HNMJCOBO_02431 9.1e-148 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
HNMJCOBO_02432 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 xylulose kinase
HNMJCOBO_02433 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
HNMJCOBO_02434 3.15e-278 xylR - - GK - - - ROK family
HNMJCOBO_02435 0.0 xynB 3.2.1.37 GH43 G ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
HNMJCOBO_02436 0.0 xynP - - G ko:K03292 - ko00000 MFS/sugar transport protein
HNMJCOBO_02437 9.78e-107 - - - E - - - phosphoribosylanthranilate isomerase activity
HNMJCOBO_02439 6.61e-144 - - - S - - - Domain of unknown function (DUF3885)
HNMJCOBO_02440 3.39e-31 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
HNMJCOBO_02441 6.65e-11 ywlA - - S - - - Uncharacterised protein family (UPF0715)
HNMJCOBO_02442 2.44e-90 - - - S - - - CAAX protease self-immunity
HNMJCOBO_02443 3.95e-124 ynaD - - J - - - Acetyltransferase (GNAT) domain
HNMJCOBO_02444 1.23e-180 ynaC - - - - - - -
HNMJCOBO_02445 2.05e-116 - - - G - - - SMI1-KNR4 cell-wall
HNMJCOBO_02446 2.39e-50 - - - - - - - -
HNMJCOBO_02448 3.06e-14 - - - - - - - -
HNMJCOBO_02449 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
HNMJCOBO_02450 9.94e-90 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 transcriptional
HNMJCOBO_02451 4.78e-310 ynbB - - P - - - COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
HNMJCOBO_02452 1.82e-293 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HNMJCOBO_02453 2.29e-226 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
HNMJCOBO_02454 1.11e-147 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
HNMJCOBO_02455 2.24e-141 - - - - - - - -
HNMJCOBO_02456 1.65e-243 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HNMJCOBO_02457 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HNMJCOBO_02458 5.01e-66 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
HNMJCOBO_02459 1.2e-30 ymzA - - - - - - -
HNMJCOBO_02460 9.4e-31 - - - - - - - -
HNMJCOBO_02461 1.28e-45 hfq - - J ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
HNMJCOBO_02462 9.69e-224 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HNMJCOBO_02463 5.41e-76 ymaF - - S - - - YmaF family
HNMJCOBO_02465 2.02e-66 ebrA - - P ko:K11814 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
HNMJCOBO_02466 2.14e-71 ebrB - - P ko:K03297,ko:K11814,ko:K11815 - ko00000,ko00002,ko02000 COG2076 Membrane transporters of cations and cationic drugs
HNMJCOBO_02467 5.98e-105 ymaD - - O - - - redox protein, regulator of disulfide bond formation
HNMJCOBO_02468 2.29e-162 ymaC - - S - - - Replication protein
HNMJCOBO_02470 0.0 aprX - - O ko:K17734 - ko00000,ko01000,ko01002 Belongs to the peptidase S8 family
HNMJCOBO_02471 4.8e-210 - - - S - - - Metallo-beta-lactamase superfamily
HNMJCOBO_02472 2.8e-81 ymzB - - - - - - -
HNMJCOBO_02473 3.54e-297 cypA 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
HNMJCOBO_02474 0.0 - - - HQ ko:K13615 - ko00000,ko01004,ko01008 Beta-ketoacyl synthase
HNMJCOBO_02475 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
HNMJCOBO_02476 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
HNMJCOBO_02477 0.0 - - - Q ko:K13612 - ko00000,ko01004,ko01008 Polyketide synthase of type I
HNMJCOBO_02478 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
HNMJCOBO_02479 2.69e-177 pksI - - I ko:K15313 - ko00000,ko01008 Belongs to the enoyl-CoA hydratase isomerase family
HNMJCOBO_02480 2.48e-184 - - - I ko:K15312 - ko00000,ko01008 enoyl-CoA hydratase
HNMJCOBO_02481 9.7e-314 pksG 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
HNMJCOBO_02482 5.31e-304 - 2.3.1.179 - I ko:K00646,ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HNMJCOBO_02483 5.46e-51 acpK - - IQ ko:K15337 - ko00000,ko01008 Phosphopantetheine attachment site
HNMJCOBO_02484 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
HNMJCOBO_02485 2.08e-239 pksD - - Q ko:K15328 - ko00000,ko01008 Acyl transferase domain
HNMJCOBO_02486 1.31e-208 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
HNMJCOBO_02487 4.02e-167 pksB 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 Polyketide biosynthesis
HNMJCOBO_02488 2.94e-141 pksA - - K - - - Transcriptional regulator
HNMJCOBO_02489 1.38e-127 ymcC - - S - - - Membrane
HNMJCOBO_02491 7.19e-93 - - - S - - - Regulatory protein YrvL
HNMJCOBO_02492 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HNMJCOBO_02493 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HNMJCOBO_02494 1.74e-119 cotE - - S ko:K06328 - ko00000 Spore coat protein
HNMJCOBO_02495 1.27e-89 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
HNMJCOBO_02496 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HNMJCOBO_02497 1.02e-278 kbl 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HNMJCOBO_02498 3.02e-255 tdh 1.1.1.103 - C ko:K00060 ko00260,map00260 ko00000,ko00001,ko01000 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
HNMJCOBO_02499 2.44e-49 spoVS - - S ko:K06416 - ko00000 Stage V sporulation protein S
HNMJCOBO_02500 6.18e-195 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 protein conserved in bacteria
HNMJCOBO_02501 4.25e-306 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
HNMJCOBO_02502 8.43e-282 pbpX - - V - - - Beta-lactamase
HNMJCOBO_02503 4.7e-239 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HNMJCOBO_02504 3.71e-300 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
HNMJCOBO_02505 3.34e-132 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HNMJCOBO_02506 3.05e-177 ymfM - - S ko:K15539 - ko00000 protein conserved in bacteria
HNMJCOBO_02507 3.91e-183 ymfK - - S - - - Protein of unknown function (DUF3388)
HNMJCOBO_02508 5.13e-55 ymfJ - - S - - - Protein of unknown function (DUF3243)
HNMJCOBO_02509 6.33e-168 ymfI 1.1.1.100 - S ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
HNMJCOBO_02510 2.37e-309 ymfH - - S - - - zinc protease
HNMJCOBO_02511 3.45e-301 albE - - S - - - Peptidase M16
HNMJCOBO_02512 2.08e-267 ymfD - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
HNMJCOBO_02513 1.28e-171 ymfC - - K ko:K03710 - ko00000,ko03000 Transcriptional regulator
HNMJCOBO_02514 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
HNMJCOBO_02515 4.94e-44 - - - S - - - YlzJ-like protein
HNMJCOBO_02516 5.01e-171 tepA - - OU - - - COG0740 Protease subunit of ATP-dependent Clp proteases
HNMJCOBO_02517 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HNMJCOBO_02518 1.57e-201 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HNMJCOBO_02519 1.2e-283 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
HNMJCOBO_02520 1.66e-247 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HNMJCOBO_02521 9.94e-142 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
HNMJCOBO_02522 4.35e-207 dpaA - - CH ko:K06410 - ko00000 Dipicolinate synthase subunit A
HNMJCOBO_02523 1.53e-56 ymxH - - S - - - YlmC YmxH family
HNMJCOBO_02524 1.62e-295 mlpA - - S - - - Belongs to the peptidase M16 family
HNMJCOBO_02525 1.29e-235 ylxY - - G - - - Sporulation protein, polysaccharide deacetylase
HNMJCOBO_02526 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HNMJCOBO_02527 7.11e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HNMJCOBO_02528 1.63e-232 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
HNMJCOBO_02529 5.18e-221 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HNMJCOBO_02530 3.29e-75 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HNMJCOBO_02531 7.83e-60 ylxP - - S ko:K09764 - ko00000 protein conserved in bacteria
HNMJCOBO_02532 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HNMJCOBO_02533 6.16e-63 ylxQ - - J - - - ribosomal protein
HNMJCOBO_02534 2.01e-57 ylxR - - K ko:K07742 - ko00000 nucleic-acid-binding protein implicated in transcription termination
HNMJCOBO_02535 5.49e-261 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
HNMJCOBO_02536 1.34e-104 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
HNMJCOBO_02537 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HNMJCOBO_02538 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HNMJCOBO_02539 6.84e-294 rasP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
HNMJCOBO_02540 1.39e-276 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HNMJCOBO_02541 5.77e-179 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
HNMJCOBO_02542 3.84e-187 uppS 2.5.1.31 - I ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HNMJCOBO_02543 9.6e-119 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HNMJCOBO_02544 5.82e-163 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
HNMJCOBO_02545 9.82e-202 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HNMJCOBO_02546 1.49e-168 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
HNMJCOBO_02547 6.91e-101 ylxL - - - - - - -
HNMJCOBO_02548 6.57e-176 sigD - - K ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HNMJCOBO_02549 3.34e-112 cheD 3.5.1.44 - NT ko:K03411 ko02030,map02030 ko00000,ko00001,ko01000,ko02035 Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
HNMJCOBO_02550 5.06e-144 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
HNMJCOBO_02551 1.56e-103 cheW - - NT ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 COG0835 Chemotaxis signal transduction protein
HNMJCOBO_02552 0.0 cheA 2.7.13.3 - NT ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 COG0643 Chemotaxis protein histidine kinase and related kinases
HNMJCOBO_02553 1.81e-252 cheB 3.1.1.61, 3.5.1.44 - NT ko:K03412 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
HNMJCOBO_02554 1.09e-200 ylxH - - D ko:K04562 - ko00000,ko02035 Belongs to the ParA family
HNMJCOBO_02555 5.65e-256 flhF - - N ko:K02404 - ko00000,ko02035 Flagellar biosynthesis regulator FlhF
HNMJCOBO_02556 0.0 flhA - - N ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HNMJCOBO_02557 2.74e-244 flhB - - N ko:K02401 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HNMJCOBO_02558 1.47e-170 fliR - - N ko:K02421 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthetic protein FliR
HNMJCOBO_02559 5.23e-50 fliQ - - N ko:K02420 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Role in flagellar biosynthesis
HNMJCOBO_02560 1.21e-141 fliP - - N ko:K02419 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Plays a role in the flagellum-specific transport system
HNMJCOBO_02561 5.54e-137 fliZ - - N ko:K02418 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthesis protein, FliO
HNMJCOBO_02562 2.12e-77 cheY - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 response regulator
HNMJCOBO_02563 1.38e-253 fliY - - N ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HNMJCOBO_02564 6.61e-231 fliM - - N ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HNMJCOBO_02565 5.59e-78 fliL - - N ko:K02415 - ko00000,ko02035 Controls the rotational direction of flagella during chemotaxis
HNMJCOBO_02566 1.09e-179 flgG - - N ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod
HNMJCOBO_02567 2.81e-96 flgD - - N ko:K02389 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod modification protein
HNMJCOBO_02568 2.31e-314 fliK - - N ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-length control protein
HNMJCOBO_02569 5.08e-84 ylxF - - S - - - MgtE intracellular N domain
HNMJCOBO_02570 1.79e-91 fliJ - - N ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar biosynthesis chaperone
HNMJCOBO_02571 2.11e-308 fliI 3.6.3.14 - NU ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 COG1157 Flagellar biosynthesis type III secretory pathway ATPase
HNMJCOBO_02572 1.92e-144 fliH - - NU ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 COG1317 Flagellar biosynthesis type III secretory pathway protein
HNMJCOBO_02573 6.08e-230 fliG - - N ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HNMJCOBO_02574 0.0 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
HNMJCOBO_02575 5.5e-53 fliE - - N ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-basal body
HNMJCOBO_02576 7.54e-99 flgC - - N ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the flagella basal body rod proteins family
HNMJCOBO_02577 1.62e-83 flgB - - N ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
HNMJCOBO_02578 1.95e-175 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HNMJCOBO_02579 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HNMJCOBO_02580 3.01e-120 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HNMJCOBO_02581 1.13e-217 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 tyrosine recombinase XerC
HNMJCOBO_02582 5.45e-314 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HNMJCOBO_02583 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HNMJCOBO_02584 6.53e-218 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
HNMJCOBO_02585 1.53e-213 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HNMJCOBO_02586 6.77e-269 sucC 6.2.1.5 - C ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HNMJCOBO_02587 1.7e-59 ylqH - - S ko:K04061 - ko00000,ko02044 homolog of the cytoplasmic domain of flagellar protein FhlB
HNMJCOBO_02588 0.0 ylqG - - - - - - -
HNMJCOBO_02589 2.04e-175 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HNMJCOBO_02590 1.4e-200 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HNMJCOBO_02591 8.14e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HNMJCOBO_02592 9.8e-177 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
HNMJCOBO_02593 1.84e-122 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HNMJCOBO_02594 3.41e-80 ylqD - - S - - - YlqD protein
HNMJCOBO_02595 1.2e-49 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
HNMJCOBO_02596 1.13e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
HNMJCOBO_02597 1.96e-308 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HNMJCOBO_02598 5.64e-66 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HNMJCOBO_02599 1.67e-114 - - - - - - - -
HNMJCOBO_02600 3.38e-227 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HNMJCOBO_02601 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
HNMJCOBO_02602 2.12e-174 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HNMJCOBO_02603 1.15e-43 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
HNMJCOBO_02604 3.5e-167 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
HNMJCOBO_02605 1.79e-216 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
HNMJCOBO_02606 8.33e-230 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HNMJCOBO_02607 6.22e-121 fapR - - K - - - Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
HNMJCOBO_02608 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HNMJCOBO_02609 1.19e-201 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
HNMJCOBO_02610 1.45e-153 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
HNMJCOBO_02611 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
HNMJCOBO_02612 3.65e-78 yloU - - S - - - protein conserved in bacteria
HNMJCOBO_02613 7.06e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
HNMJCOBO_02614 2.83e-157 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
HNMJCOBO_02615 4.68e-153 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
HNMJCOBO_02616 1.37e-215 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HNMJCOBO_02617 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
HNMJCOBO_02618 3.54e-180 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
HNMJCOBO_02619 8.79e-263 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HNMJCOBO_02620 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HNMJCOBO_02621 4.98e-223 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HNMJCOBO_02622 4.8e-109 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HNMJCOBO_02623 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HNMJCOBO_02624 5.13e-286 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HNMJCOBO_02625 3.6e-38 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HNMJCOBO_02626 5.73e-143 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
HNMJCOBO_02627 3.97e-54 ylzA - - S ko:K09777 - ko00000 Belongs to the UPF0296 family
HNMJCOBO_02628 9.81e-201 yloC - - S - - - stress-induced protein
HNMJCOBO_02629 0.0 yloB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 COG0474 Cation transport ATPase
HNMJCOBO_02630 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
HNMJCOBO_02631 2.19e-106 sirC 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Siroheme synthase
HNMJCOBO_02632 1.19e-186 sirB 4.99.1.4 - S ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sirohydrochlorin ferrochelatase
HNMJCOBO_02633 1.24e-186 cobA 2.1.1.107 - H ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
HNMJCOBO_02634 5.56e-142 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
HNMJCOBO_02635 2.62e-285 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
HNMJCOBO_02636 7.32e-230 cysP - - P ko:K16331 - ko00000,ko02000 phosphate transporter
HNMJCOBO_02637 1.03e-182 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
HNMJCOBO_02639 4.26e-147 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HNMJCOBO_02640 2.67e-163 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HNMJCOBO_02641 8.59e-221 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HNMJCOBO_02642 4.31e-182 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
HNMJCOBO_02643 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarB family
HNMJCOBO_02644 1.31e-269 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
HNMJCOBO_02645 9.71e-317 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HNMJCOBO_02646 4.21e-213 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
HNMJCOBO_02647 1.06e-293 pyrP - - F ko:K02824 - ko00000,ko02000 Xanthine uracil
HNMJCOBO_02648 4.45e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HNMJCOBO_02649 3.52e-225 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
HNMJCOBO_02650 2.71e-103 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HNMJCOBO_02651 1.07e-81 ylyA - - T - - - COG1734 DnaK suppressor protein
HNMJCOBO_02652 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HNMJCOBO_02653 6.44e-100 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
HNMJCOBO_02654 4.28e-178 ylmH - - S - - - conserved protein, contains S4-like domain
HNMJCOBO_02655 1.22e-53 ylmG - - S ko:K02221 - ko00000,ko02044 membrane
HNMJCOBO_02656 5.44e-88 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HNMJCOBO_02657 3.15e-162 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HNMJCOBO_02658 5.53e-205 ylmD - - S ko:K05810 - ko00000,ko01000 Belongs to the multicopper oxidase YfiH RL5 family
HNMJCOBO_02659 3.58e-51 ylmC - - S - - - sporulation protein
HNMJCOBO_02660 0.0 argE - - E ko:K20895 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Acetylornithine deacetylase
HNMJCOBO_02661 3.84e-189 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
HNMJCOBO_02662 7.99e-180 sigG - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HNMJCOBO_02663 1.48e-160 sigE - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HNMJCOBO_02664 1.06e-220 spoIIGA - - M ko:K06383 - ko00000,ko01000,ko01002 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
HNMJCOBO_02665 0.0 bpr - - O ko:K13276 - ko00000,ko01000,ko01002,ko03110 COG1404 Subtilisin-like serine proteases
HNMJCOBO_02666 1.84e-260 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HNMJCOBO_02667 4.88e-299 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HNMJCOBO_02668 5.37e-76 sbp - - S - - - small basic protein
HNMJCOBO_02669 8.67e-132 ylxX - - S - - - protein conserved in bacteria
HNMJCOBO_02670 3.45e-146 ylxW - - S - - - protein conserved in bacteria
HNMJCOBO_02671 1.37e-177 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HNMJCOBO_02672 1.3e-211 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
HNMJCOBO_02673 3.68e-255 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HNMJCOBO_02674 6.64e-237 spoVE - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
HNMJCOBO_02675 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HNMJCOBO_02676 9.59e-220 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HNMJCOBO_02677 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HNMJCOBO_02678 0.0 spoVD - - M ko:K08384 ko00550,map00550 ko00000,ko00001,ko01011 stage V sporulation protein D
HNMJCOBO_02679 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
HNMJCOBO_02680 3.42e-68 ftsL - - D - - - Essential cell division protein
HNMJCOBO_02681 4.97e-220 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HNMJCOBO_02682 9.82e-102 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
HNMJCOBO_02683 0.0 bshC - - S ko:K22136 - ko00000 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
HNMJCOBO_02684 1.6e-214 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HNMJCOBO_02685 3.26e-116 ylbP - - K - - - n-acetyltransferase
HNMJCOBO_02686 1.35e-106 ylbO - - S ko:K06314 - ko00000,ko03000 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
HNMJCOBO_02687 1.71e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
HNMJCOBO_02688 3.44e-117 ylbN - - S ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
HNMJCOBO_02690 5.94e-301 ylbM - - S - - - Belongs to the UPF0348 family
HNMJCOBO_02691 7.81e-239 ylbL - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
HNMJCOBO_02692 3.64e-176 ylbK - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
HNMJCOBO_02693 5.5e-282 ylbJ - - S - - - Sporulation integral membrane protein YlbJ
HNMJCOBO_02694 3.8e-111 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HNMJCOBO_02695 3.51e-125 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
HNMJCOBO_02696 5.1e-51 ylbG - - S - - - UPF0298 protein
HNMJCOBO_02697 2.34e-97 ylbF - - S - - - Belongs to the UPF0342 family
HNMJCOBO_02698 1.73e-48 ylbE - - S - - - YlbE-like protein
HNMJCOBO_02699 3.24e-89 ylbD - - S - - - Putative coat protein
HNMJCOBO_02700 4.58e-258 ylbC - - S - - - protein with SCP PR1 domains
HNMJCOBO_02701 1.08e-97 ylbB - - T - - - COG0517 FOG CBS domain
HNMJCOBO_02702 1.61e-81 ylbA - - S - - - YugN-like family
HNMJCOBO_02703 1.04e-214 ctaG - - S ko:K02862 - ko00000 cytochrome c oxidase
HNMJCOBO_02704 6.09e-70 ctaF 1.9.3.1 - C ko:K02277 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
HNMJCOBO_02705 1.84e-145 ctaE 1.9.3.1 - C ko:K02276 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
HNMJCOBO_02706 0.0 ctaD 1.9.3.1 - C ko:K02274 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HNMJCOBO_02707 5.85e-253 ctaC 1.9.3.1 - C ko:K02275 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
HNMJCOBO_02708 1.7e-208 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HNMJCOBO_02709 2.97e-214 ctaA - - O ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 ko00000,ko00001,ko00002,ko03029 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
HNMJCOBO_02710 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HNMJCOBO_02711 2.57e-273 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
HNMJCOBO_02712 6.94e-59 ylaN - - S - - - Belongs to the UPF0358 family
HNMJCOBO_02713 4.25e-220 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
HNMJCOBO_02714 9.32e-112 ylaL - - S - - - Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HNMJCOBO_02715 3.76e-316 ylaK - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
HNMJCOBO_02716 2.97e-127 ylaJ - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HNMJCOBO_02717 8.92e-44 ylaI - - S - - - protein conserved in bacteria
HNMJCOBO_02718 4.4e-63 ylaH - - S - - - YlaH-like protein
HNMJCOBO_02719 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
HNMJCOBO_02720 2.21e-30 - - - S - - - Family of unknown function (DUF5325)
HNMJCOBO_02721 1.74e-57 ylaE - - - - - - -
HNMJCOBO_02723 4.51e-118 ylaC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HNMJCOBO_02724 1.44e-56 ylaB - - - - - - -
HNMJCOBO_02725 0.0 ylaA - - - - - - -
HNMJCOBO_02726 0.0 mpl 3.4.24.28, 3.4.24.29 - E ko:K01400,ko:K01401,ko:K19351 ko01503,ko05150,map01503,map05150 ko00000,ko00001,ko01000,ko01002 Peptidase M4
HNMJCOBO_02727 1.28e-223 - - - Q - - - Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HNMJCOBO_02728 1.48e-100 ykzC - - S - - - Acetyltransferase (GNAT) family
HNMJCOBO_02729 9.48e-195 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase
HNMJCOBO_02730 4.48e-35 ykzI - - - - - - -
HNMJCOBO_02731 1.3e-152 yktB - - S - - - Belongs to the UPF0637 family
HNMJCOBO_02732 1.34e-56 yktA - - S - - - Belongs to the UPF0223 family
HNMJCOBO_02733 0.0 speA 4.1.1.17, 4.1.1.19 - E ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Arginine
HNMJCOBO_02734 4.55e-83 slp - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
HNMJCOBO_02735 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HNMJCOBO_02736 1.47e-301 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HNMJCOBO_02737 1.75e-227 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HNMJCOBO_02738 1.06e-258 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HNMJCOBO_02739 6.82e-149 ykyA - - L - - - Putative cell-wall binding lipoprotein
HNMJCOBO_02740 2.24e-19 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
HNMJCOBO_02741 3.96e-131 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HNMJCOBO_02742 2.03e-187 ykrA - - S - - - hydrolases of the HAD superfamily
HNMJCOBO_02743 8.98e-42 ykzG - - S - - - Belongs to the UPF0356 family
HNMJCOBO_02744 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HNMJCOBO_02745 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HNMJCOBO_02746 1.68e-148 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
HNMJCOBO_02747 9.21e-208 ykqA - - P - - - Gamma-glutamyl cyclotransferase, AIG2-like
HNMJCOBO_02748 4.59e-307 kinC 2.7.13.3 - T ko:K07698 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
HNMJCOBO_02749 2.63e-58 abrB - - K ko:K06284 - ko00000,ko03000 of stationary sporulation gene expression
HNMJCOBO_02750 6.17e-234 mreBH - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod-share determining protein MreBH
HNMJCOBO_02751 1.09e-18 - - - S - - - Uncharacterized protein YkpC
HNMJCOBO_02752 2.07e-303 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
HNMJCOBO_02753 2.99e-217 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HNMJCOBO_02754 0.0 ykpA - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HNMJCOBO_02755 5.43e-52 ykoA - - - - - - -
HNMJCOBO_02756 1.72e-134 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HNMJCOBO_02757 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
HNMJCOBO_02758 9.99e-216 pfkB 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
HNMJCOBO_02759 1.49e-175 fruR - - K ko:K03436 - ko00000,ko03000 Transcriptional regulator
HNMJCOBO_02760 2.1e-269 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
HNMJCOBO_02761 6.1e-160 yknY - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HNMJCOBO_02762 4.93e-235 yknX - - M ko:K02005,ko:K13888 - ko00000,ko00002,ko02000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HNMJCOBO_02763 1.6e-151 yknW - - S - - - Yip1 domain
HNMJCOBO_02764 0.0 yknV - - V ko:K02021,ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
HNMJCOBO_02765 0.0 yknU - - V ko:K06147,ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
HNMJCOBO_02766 6.92e-45 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HNMJCOBO_02767 3.83e-109 moaE 2.8.1.12 - H ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 COG0314 Molybdopterin converting factor, large subunit
HNMJCOBO_02768 5.71e-121 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
HNMJCOBO_02769 1.68e-310 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 molybdopterin
HNMJCOBO_02770 1.53e-244 moeB 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HNMJCOBO_02771 9.21e-142 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HNMJCOBO_02772 1.47e-201 yknT - - - ko:K06437 - ko00000 -
HNMJCOBO_02773 4.71e-122 rok - - K - - - Repressor of ComK
HNMJCOBO_02774 6.25e-106 ykuV - - CO - - - thiol-disulfide
HNMJCOBO_02775 9.78e-130 ykuU - - O - - - Alkyl hydroperoxide reductase
HNMJCOBO_02776 4.1e-181 ykuT - - M ko:K22044 - ko00000,ko02000 Mechanosensitive ion channel
HNMJCOBO_02777 7.23e-51 ykuS - - S - - - Belongs to the UPF0180 family
HNMJCOBO_02778 7.99e-276 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HNMJCOBO_02779 1.31e-125 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HNMJCOBO_02780 1.3e-104 fld - - C ko:K03839 - ko00000 Flavodoxin
HNMJCOBO_02781 1.33e-226 ykuO - - - - - - -
HNMJCOBO_02782 7.72e-114 - - - C ko:K03839 - ko00000 Flavodoxin domain
HNMJCOBO_02783 6.52e-216 ccpC - - K - - - Transcriptional regulator
HNMJCOBO_02784 5.15e-100 ykuL - - S - - - CBS domain
HNMJCOBO_02785 7.83e-38 ykzF - - S - - - Antirepressor AbbA
HNMJCOBO_02786 6.44e-122 - - - S ko:K09776 - ko00000 Ribonuclease H-like
HNMJCOBO_02787 5.16e-50 ykuJ - - S - - - protein conserved in bacteria
HNMJCOBO_02788 1.76e-298 ykuI - - T - - - Diguanylate phosphodiesterase
HNMJCOBO_02790 0.0 ybfG - - M - - - Putative peptidoglycan binding domain
HNMJCOBO_02791 1.83e-182 fadH 1.3.1.34 - IQ ko:K00219 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HNMJCOBO_02792 3.48e-212 ykuE - - S ko:K07098 - ko00000 Metallophosphoesterase
HNMJCOBO_02793 7.1e-116 ykuD - - S - - - protein conserved in bacteria
HNMJCOBO_02794 8.89e-306 ykuC - - EGP - - - COG0477 Permeases of the major facilitator superfamily
HNMJCOBO_02795 3.71e-110 ykyB - - S - - - YkyB-like protein
HNMJCOBO_02796 4.24e-217 cheV - - T ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 Chemotaxis protein CheV
HNMJCOBO_02797 1.05e-22 - - - - - - - -
HNMJCOBO_02798 5.32e-286 patA - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HNMJCOBO_02799 0.0 kinA 2.7.13.3 - T ko:K02491 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HNMJCOBO_02800 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
HNMJCOBO_02801 5.36e-172 ykwD - - J - - - protein with SCP PR1 domains
HNMJCOBO_02802 1.4e-203 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
HNMJCOBO_02803 0.0 mcpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
HNMJCOBO_02804 5.49e-170 ykwB - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HNMJCOBO_02805 2.13e-257 splB 4.1.99.14 - L ko:K03716 - ko00000,ko01000 Spore photoproduct lyase
HNMJCOBO_02806 1.54e-51 splA - - S ko:K06315 - ko00000,ko03000 Transcriptional regulator
HNMJCOBO_02807 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HNMJCOBO_02808 1.51e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPr
HNMJCOBO_02809 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HNMJCOBO_02810 3.41e-168 glcT - - K ko:K03480,ko:K03488 - ko00000,ko03000 antiterminator
HNMJCOBO_02812 3.28e-230 ykvZ - - K - - - Transcriptional regulator
HNMJCOBO_02814 7.85e-266 ykvY 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
HNMJCOBO_02815 3.99e-09 - - - - - - - -
HNMJCOBO_02816 0.0 zosA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
HNMJCOBO_02817 5.79e-117 stoA - - CO - - - thiol-disulfide
HNMJCOBO_02818 1.12e-302 ykvU - - S - - - COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HNMJCOBO_02819 9.09e-142 ykvT 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell Wall Hydrolase
HNMJCOBO_02820 2.6e-39 - - - - - - - -
HNMJCOBO_02821 5.43e-35 ykvS - - S - - - protein conserved in bacteria
HNMJCOBO_02822 2.67e-62 ykvR - - S - - - Protein of unknown function (DUF3219)
HNMJCOBO_02823 2.5e-169 - - - G - - - Glycosyl hydrolases family 18
HNMJCOBO_02824 1.85e-48 - 3.5.1.104 - M ko:K22278 - ko00000,ko01000 LysM domain
HNMJCOBO_02825 2.69e-275 - - - M - - - Glycosyl transferases group 1
HNMJCOBO_02826 9.35e-173 ykvO - - IQ - - - Enoyl-(Acyl carrier protein) reductase
HNMJCOBO_02827 2.8e-81 ykvN - - K - - - Transcriptional regulator
HNMJCOBO_02828 2.36e-125 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HNMJCOBO_02829 3.56e-179 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HNMJCOBO_02830 6.96e-105 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
HNMJCOBO_02831 1.11e-161 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HNMJCOBO_02832 4.26e-230 ykvI - - S - - - membrane
HNMJCOBO_02833 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
HNMJCOBO_02834 2.01e-178 motA - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
HNMJCOBO_02835 4.91e-170 motB - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
HNMJCOBO_02836 5.17e-99 ykvE - - K ko:K15973 - ko00000,ko03000 transcriptional
HNMJCOBO_02837 0.0 kinD 2.7.13.3 - T ko:K13532 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
HNMJCOBO_02838 5.84e-95 eag - - - - - - -
HNMJCOBO_02840 8.82e-68 - - - S - - - Protein of unknown function (DUF1232)
HNMJCOBO_02841 1.5e-123 mtnD 1.13.11.53, 1.13.11.54 - S ko:K08967 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
HNMJCOBO_02842 4.52e-147 mtnB 4.2.1.109 - E ko:K08964 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
HNMJCOBO_02843 1.07e-176 mtnX 3.1.3.87 - E ko:K08966 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
HNMJCOBO_02844 3.39e-295 mtnW 5.3.2.5 - G ko:K08965 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
HNMJCOBO_02845 4.81e-296 mtnE - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HNMJCOBO_02846 1.99e-193 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HNMJCOBO_02847 2.47e-293 mtnK 2.7.1.100 - F ko:K00899 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
HNMJCOBO_02848 1.62e-253 mtnA 5.3.1.23 - E ko:K08963 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
HNMJCOBO_02850 2.76e-115 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HNMJCOBO_02851 0.0 kinE 2.7.13.3 - T ko:K13533 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HNMJCOBO_02852 3.34e-244 ykrP - - G - - - COG3594 Fucose 4-O-acetylase and related acetyltransferases
HNMJCOBO_02853 8.33e-31 ykzE - - - - - - -
HNMJCOBO_02855 1.82e-310 ktrD - - P - - - COG0168 Trk-type K transport systems, membrane components
HNMJCOBO_02856 9.74e-200 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
HNMJCOBO_02857 7.68e-160 ykrK - - S - - - Domain of unknown function (DUF1836)
HNMJCOBO_02858 1.4e-36 sspD - - S ko:K06421 - ko00000 small acid-soluble spore protein
HNMJCOBO_02859 9.33e-219 rsgI - - S - - - Anti-sigma factor N-terminus
HNMJCOBO_02860 1.8e-167 sigI - - K ko:K03093 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HNMJCOBO_02861 4.63e-227 ykoY - - P - - - COG0861 Membrane protein TerC, possibly involved in tellurium resistance
HNMJCOBO_02862 4.48e-153 ykoX - - S - - - membrane-associated protein
HNMJCOBO_02863 0.0 ykoW 2.7.7.65 - T ko:K21023 ko02025,map02025 ko00000,ko00001,ko01000 Diguanylate cyclase
HNMJCOBO_02864 7.55e-206 ku - - L ko:K10979 ko03450,map03450 ko00000,ko00001,ko03400 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HNMJCOBO_02865 0.0 ligD 6.5.1.1 - L ko:K01971 ko03450,map03450 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA ligase
HNMJCOBO_02866 5.72e-239 ykoT - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
HNMJCOBO_02867 0.0 ykoS - - - - - - -
HNMJCOBO_02868 6.18e-198 ykoQ - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
HNMJCOBO_02869 1.44e-128 ykoP - - G - - - polysaccharide deacetylase
HNMJCOBO_02870 1.33e-278 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
HNMJCOBO_02871 9.83e-106 ykoM - - K ko:K15973 - ko00000,ko03000 transcriptional
HNMJCOBO_02872 2.51e-35 ykoL - - - - - - -
HNMJCOBO_02873 1.63e-25 - - - - - - - -
HNMJCOBO_02874 1.49e-70 tnrA - - K - - - transcriptional
HNMJCOBO_02875 9.86e-300 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
HNMJCOBO_02877 1.45e-08 - - - - - - - -
HNMJCOBO_02878 1.3e-111 ykoJ - - S - - - Peptidase propeptide and YPEB domain
HNMJCOBO_02879 3.74e-143 ykoI - - S - - - Peptidase propeptide and YPEB domain
HNMJCOBO_02880 8.98e-309 ykoH - - T - - - Histidine kinase
HNMJCOBO_02881 2.13e-159 ykoG - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HNMJCOBO_02882 2.44e-142 ykoF - - S - - - YKOF-related Family
HNMJCOBO_02883 1.39e-127 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
HNMJCOBO_02884 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HNMJCOBO_02885 3.12e-174 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
HNMJCOBO_02886 3.99e-193 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HNMJCOBO_02887 1.49e-225 isp - - O ko:K13275 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
HNMJCOBO_02888 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HNMJCOBO_02889 5.67e-115 guaD 3.5.4.3 - FJ ko:K01487 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 COG0590 Cytosine adenosine deaminases
HNMJCOBO_02891 8.15e-94 ohrB - - O - - - Organic hydroperoxide resistance protein
HNMJCOBO_02892 1.42e-97 ohrR - - K - - - COG1846 Transcriptional regulators
HNMJCOBO_02893 2.39e-93 ohrA - - O - - - Organic hydroperoxide resistance protein
HNMJCOBO_02895 3.77e-288 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HNMJCOBO_02896 3.68e-256 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HNMJCOBO_02897 1.66e-217 purU 3.5.1.10 - F ko:K01433 ko00630,ko00670,map00630,map00670 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
HNMJCOBO_02898 1.36e-66 ykkD - - P ko:K18925 - ko00000,ko00002,ko02000 Multidrug resistance protein
HNMJCOBO_02899 1.27e-72 ykkC - - P ko:K18924 - ko00000,ko00002,ko02000 Multidrug resistance protein
HNMJCOBO_02900 1.46e-127 ykkB - - J - - - COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HNMJCOBO_02901 2.15e-126 ykkA - - S - - - Protein of unknown function (DUF664)
HNMJCOBO_02902 3.25e-166 ykjA - - S - - - Protein of unknown function (DUF421)
HNMJCOBO_02903 3.55e-14 - - - - - - - -
HNMJCOBO_02904 5.35e-289 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HNMJCOBO_02905 1.55e-119 ykhA - - I - - - Acyl-CoA hydrolase
HNMJCOBO_02906 1.78e-205 ykgA - - E - - - Amidinotransferase
HNMJCOBO_02907 5.69e-261 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconolactonase
HNMJCOBO_02908 8.44e-237 ykfD - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HNMJCOBO_02909 4.96e-217 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HNMJCOBO_02910 5.65e-256 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
HNMJCOBO_02911 9.61e-225 ykfA 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
HNMJCOBO_02913 0.0 dppE - - E ko:K16199 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
HNMJCOBO_02914 1.64e-237 dppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HNMJCOBO_02915 3.02e-224 dppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HNMJCOBO_02916 9.7e-204 dppB - - P ko:K16200 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HNMJCOBO_02917 1.15e-195 dppA - - E ko:K16203 - ko00000,ko01000,ko01002 D-aminopeptidase
HNMJCOBO_02918 2.35e-178 proG 1.5.1.2 - E ko:K00286,ko:K02239 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko02044 Pyrroline-5-carboxylate reductase
HNMJCOBO_02919 2.41e-284 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HNMJCOBO_02921 2.21e-229 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
HNMJCOBO_02922 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HNMJCOBO_02924 4e-233 ykcA - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
HNMJCOBO_02925 1.49e-308 steT - - E ko:K03294 - ko00000 amino acid
HNMJCOBO_02926 1.85e-144 ykaA - - P ko:K07220 - ko00000 COG1392 Phosphate transport regulator (distant homolog of PhoU)
HNMJCOBO_02927 1.54e-225 pit - - P ko:K03306 - ko00000 phosphate transporter
HNMJCOBO_02928 1.19e-175 spoIISA - - S ko:K06388 - ko00000 Toxin SpoIISA, type II toxin-antitoxin system
HNMJCOBO_02929 1.78e-31 spoIISB - - S ko:K06389 - ko00000 Stage II sporulation protein SB
HNMJCOBO_02930 5.76e-212 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
HNMJCOBO_02931 9.5e-52 xhlB - - S - - - SPP1 phage holin
HNMJCOBO_02932 2.32e-47 xhlA - - S - - - Haemolysin XhlA
HNMJCOBO_02933 1.82e-12 - - - S - - - Phage uncharacterised protein (Phage_XkdX)
HNMJCOBO_02935 5.5e-170 - - - - - - - -
HNMJCOBO_02936 4.43e-56 - - - - - - - -
HNMJCOBO_02937 1.94e-135 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
HNMJCOBO_02938 7.59e-245 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
HNMJCOBO_02939 1.97e-92 xkdS - - S - - - Protein of unknown function (DUF2634)
HNMJCOBO_02940 4.32e-53 xkdR - - S - - - Protein of unknown function (DUF2577)
HNMJCOBO_02941 2.31e-232 xkdQ - - G - - - NLP P60 protein
HNMJCOBO_02942 1.77e-158 xkdP - - S - - - Lysin motif
HNMJCOBO_02943 0.0 xkdO - - L - - - Transglycosylase SLT domain
HNMJCOBO_02944 3.34e-101 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
HNMJCOBO_02945 6.01e-99 xkdM - - S - - - Phage tail tube protein
HNMJCOBO_02946 0.0 xkdK - - S - - - Phage tail sheath C-terminal domain
HNMJCOBO_02947 9.26e-98 xkdJ - - - - - - -
HNMJCOBO_02948 1.96e-113 xkdI - - S - - - Bacteriophage HK97-gp10, putative tail-component
HNMJCOBO_02949 5.02e-84 yqbH - - S - - - Domain of unknown function (DUF3599)
HNMJCOBO_02950 3.85e-81 yqbG - - S - - - Protein of unknown function (DUF3199)
HNMJCOBO_02951 3.91e-217 xkdG - - S - - - Phage capsid family
HNMJCOBO_02952 9.88e-177 xkdF3 - - L - - - Putative phage serine protease XkdF
HNMJCOBO_02953 0.0 yqbA - - S - - - portal protein
HNMJCOBO_02954 0.0 xtmB - - S ko:K06909 - ko00000 phage terminase, large subunit
HNMJCOBO_02955 1.95e-178 xtmA - - L ko:K07474 - ko00000 phage terminase small subunit
HNMJCOBO_02956 1.35e-108 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
HNMJCOBO_02960 3.55e-151 xkdC - - L - - - Bacterial dnaA protein
HNMJCOBO_02961 3.73e-203 xkdB - - K - - - sequence-specific DNA binding
HNMJCOBO_02963 2.01e-74 xre - - K - - - Helix-turn-helix XRE-family like proteins
HNMJCOBO_02964 1.79e-143 xkdA - - E - - - IrrE N-terminal-like domain
HNMJCOBO_02965 4.54e-204 yjqC - - P ko:K07217 - ko00000 Catalase
HNMJCOBO_02966 5.99e-143 yjqB - - S - - - Pfam:DUF867
HNMJCOBO_02967 3.87e-80 yjqA - - S - - - Bacterial PH domain
HNMJCOBO_02968 4.58e-219 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
HNMJCOBO_02969 4.23e-54 - - - S - - - YCII-related domain
HNMJCOBO_02971 8.59e-272 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
HNMJCOBO_02972 6.08e-314 VCP - - O - - - AAA domain (dynein-related subfamily)
HNMJCOBO_02973 2.71e-103 yjoA - - S - - - DinB family
HNMJCOBO_02974 4.56e-167 yjnA - - S ko:K07090 - ko00000 membrane transporter protein
HNMJCOBO_02975 0.0 uxaA 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
HNMJCOBO_02976 0.0 uxaB 1.1.1.58 - G ko:K00041 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 tagaturonate reductase activity
HNMJCOBO_02977 6.95e-238 exuR - - K ko:K02529 - ko00000,ko03000 transcriptional
HNMJCOBO_02978 1.37e-289 exuT - - G ko:K03535,ko:K08191 - ko00000,ko02000 Sugar (and other) transporter
HNMJCOBO_02979 1.34e-196 yjmF - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HNMJCOBO_02980 7.91e-273 uxuA 4.2.1.8 - G ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of D-mannonate
HNMJCOBO_02981 9.24e-246 yjmD 1.1.1.380 - E ko:K08322 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
HNMJCOBO_02982 2.08e-241 allD 1.1.1.350 - C ko:K00073 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000 Belongs to the LDH2 MDH2 oxidoreductase family
HNMJCOBO_02983 3.56e-313 - - - G ko:K03292 - ko00000 symporter YjmB
HNMJCOBO_02984 0.0 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
HNMJCOBO_02985 3.56e-279 yjlD 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
HNMJCOBO_02986 3.98e-87 yjlC - - S - - - Protein of unknown function (DUF1641)
HNMJCOBO_02987 2.36e-116 yjlB - - S - - - Cupin domain
HNMJCOBO_02988 8.58e-223 yjlA - - EG - - - Putative multidrug resistance efflux transporter
HNMJCOBO_02989 2.79e-175 yjkB - - P ko:K02068 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HNMJCOBO_02990 9.04e-156 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
HNMJCOBO_02991 8.69e-189 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
HNMJCOBO_02992 1.11e-41 - - - - - - - -
HNMJCOBO_02993 1.76e-279 yjiC - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HNMJCOBO_02994 9.15e-284 yjiB 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
HNMJCOBO_02996 1.51e-146 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
HNMJCOBO_02998 6.51e-122 yjgD - - S - - - Protein of unknown function (DUF1641)
HNMJCOBO_02999 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
HNMJCOBO_03000 5.79e-132 yjgB - - S - - - Domain of unknown function (DUF4309)
HNMJCOBO_03001 1.38e-59 yjgA - - T - - - Protein of unknown function (DUF2809)
HNMJCOBO_03002 3.48e-214 yjfC - - O - - - Predicted Zn-dependent protease (DUF2268)
HNMJCOBO_03003 1.13e-29 yjfB - - S - - - Putative motility protein
HNMJCOBO_03004 2.22e-108 - - - S - - - Protein of unknown function (DUF2690)
HNMJCOBO_03005 0.0 yjeA 3.5.1.104 - G ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
HNMJCOBO_03007 2.16e-223 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HNMJCOBO_03008 2.31e-69 yjdJ - - S - - - Domain of unknown function (DUF4306)
HNMJCOBO_03009 6.12e-40 - - - S - - - Domain of unknown function (DUF4177)
HNMJCOBO_03010 1.01e-105 ebsC - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HNMJCOBO_03012 1.26e-117 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
HNMJCOBO_03013 3.93e-77 yjdF3 - - S - - - Protein of unknown function (DUF2992)
HNMJCOBO_03014 1.03e-239 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
HNMJCOBO_03015 0.0 manP 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HNMJCOBO_03016 0.0 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 transcriptional antiterminator
HNMJCOBO_03017 0.000759 - - - - - - - -
HNMJCOBO_03018 2.81e-180 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
HNMJCOBO_03019 1.27e-61 yjcS - - S - - - Antibiotic biosynthesis monooxygenase
HNMJCOBO_03020 3.29e-121 yqaS - - L - - - DNA packaging
HNMJCOBO_03021 1.01e-65 - - - S - - - YjcQ protein
HNMJCOBO_03022 5.68e-100 yjcP - - - - - - -
HNMJCOBO_03023 2.24e-106 - - - L - - - Transposase
HNMJCOBO_03026 1.52e-68 yjcN - - - - - - -
HNMJCOBO_03027 3.75e-269 - - - S - - - Putative amidase domain
HNMJCOBO_03030 1.74e-272 yjcL - - S - - - Protein of unknown function (DUF819)
HNMJCOBO_03031 1.68e-126 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Alanine acetyltransferase
HNMJCOBO_03032 7.47e-280 metC 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
HNMJCOBO_03033 4.65e-272 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
HNMJCOBO_03034 7.77e-177 yjcH - - P ko:K07214 - ko00000 COG2382 Enterochelin esterase and related enzymes
HNMJCOBO_03035 1.2e-121 yjcG - - J - - - Belongs to the 2H phosphoesterase superfamily. YjcG family
HNMJCOBO_03036 2.22e-93 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HNMJCOBO_03037 6.31e-51 - - - - - - - -
HNMJCOBO_03038 0.0 yjcD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
HNMJCOBO_03039 1.88e-52 spoVIF - - S - - - Stage VI sporulation protein F
HNMJCOBO_03042 5.03e-75 yjcA - - S - - - Protein of unknown function (DUF1360)
HNMJCOBO_03043 1.18e-71 cotV - - S ko:K06340 - ko00000 Spore Coat Protein X and V domain
HNMJCOBO_03044 8.7e-34 cotW - - - ko:K06341 - ko00000 -
HNMJCOBO_03045 2.87e-94 cotX - - S ko:K06342 - ko00000 Spore Coat Protein X and V domain
HNMJCOBO_03046 6.3e-124 cotY - - S ko:K06343 - ko00000 Spore coat protein Z
HNMJCOBO_03047 3.92e-107 cotZ - - S ko:K06344 - ko00000 Spore coat protein
HNMJCOBO_03048 2.56e-104 yjbX - - S - - - Spore coat protein
HNMJCOBO_03049 5.03e-182 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
HNMJCOBO_03050 1.14e-189 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
HNMJCOBO_03051 1.77e-237 thiF 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HNMJCOBO_03052 6.78e-174 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
HNMJCOBO_03053 1.8e-40 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 thiamine diphosphate biosynthetic process
HNMJCOBO_03054 5.8e-271 thiO 1.4.3.19, 1.4.5.1 - E ko:K00285,ko:K03153 ko00360,ko00730,ko01100,map00360,map00730,map01100 ko00000,ko00001,ko01000 Glycine oxidase
HNMJCOBO_03055 1.91e-137 tenI 5.3.99.10 - H ko:K10810 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Transcriptional regulator TenI
HNMJCOBO_03056 5.7e-177 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HNMJCOBO_03057 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HNMJCOBO_03058 8.09e-181 prpE 3.1.3.16, 3.6.1.41 - T ko:K01090,ko:K01525 ko00230,map00230 ko00000,ko00001,ko01000 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
HNMJCOBO_03059 2.12e-202 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
HNMJCOBO_03060 2.94e-194 nadK 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HNMJCOBO_03061 5.06e-145 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 GTP pyrophosphokinase
HNMJCOBO_03062 7.61e-81 yjbL - - S - - - Belongs to the UPF0738 family
HNMJCOBO_03063 7.02e-128 yjbK - - S - - - protein conserved in bacteria
HNMJCOBO_03064 1.39e-126 yjbJ - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HNMJCOBO_03065 2.46e-93 yjbI - - S ko:K06886 - ko00000 Bacterial-like globin
HNMJCOBO_03066 7.63e-218 yjbH - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
HNMJCOBO_03068 2.68e-28 - - - - - - - -
HNMJCOBO_03069 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
HNMJCOBO_03070 3.6e-281 coiA - - S ko:K06198 - ko00000 Competence protein
HNMJCOBO_03071 4.65e-149 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HNMJCOBO_03072 7.1e-144 yjbE - - P - - - Integral membrane protein TerC family
HNMJCOBO_03073 1.01e-87 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HNMJCOBO_03074 8.88e-132 yjbC - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HNMJCOBO_03075 3.22e-265 yjbB - - EGP - - - Major Facilitator Superfamily
HNMJCOBO_03076 3.64e-219 oppF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HNMJCOBO_03077 3.22e-248 oppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HNMJCOBO_03078 7.55e-212 oppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HNMJCOBO_03079 1.4e-210 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HNMJCOBO_03080 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
HNMJCOBO_03081 6.15e-235 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
HNMJCOBO_03082 3.18e-190 yjbA - - S - - - Belongs to the UPF0736 family
HNMJCOBO_03083 1.03e-208 appC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HNMJCOBO_03084 6.73e-216 appB - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HNMJCOBO_03085 0.0 appA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
HNMJCOBO_03086 4.88e-236 appF - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HNMJCOBO_03087 1.02e-232 appD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HNMJCOBO_03088 7.79e-192 yjaZ - - O - - - Zn-dependent protease
HNMJCOBO_03089 3.06e-302 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HNMJCOBO_03090 1.61e-221 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HNMJCOBO_03091 2.67e-38 yjzB - - - - - - -
HNMJCOBO_03092 1.07e-35 comZ - - S ko:K02254 - ko00000,ko02044 ComZ
HNMJCOBO_03093 3.7e-234 med - - S ko:K05519,ko:K07335 - ko00000,ko03000 Transcriptional activator protein med
HNMJCOBO_03094 6.33e-133 yjaV - - - - - - -
HNMJCOBO_03095 4.88e-182 yjaU - - I - - - carboxylic ester hydrolase activity
HNMJCOBO_03096 2.17e-23 yjzD - - S - - - Protein of unknown function (DUF2929)
HNMJCOBO_03097 2.51e-39 yjzC - - S - - - YjzC-like protein
HNMJCOBO_03098 1.43e-223 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HNMJCOBO_03099 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase ammonia chain
HNMJCOBO_03100 1.35e-261 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
HNMJCOBO_03101 1.55e-274 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
HNMJCOBO_03102 1.27e-175 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
HNMJCOBO_03103 1.43e-292 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HNMJCOBO_03104 8.29e-252 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HNMJCOBO_03105 3.24e-114 yitZ - - G - - - Major Facilitator Superfamily
HNMJCOBO_03106 0.0 yitY - - C - - - D-arabinono-1,4-lactone oxidase
HNMJCOBO_03107 1.74e-31 - - - S - - - Proteolipid membrane potential modulator
HNMJCOBO_03108 3.26e-68 yitW - - S - - - metal-sulfur cluster biosynthetic enzyme
HNMJCOBO_03109 1.02e-184 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
HNMJCOBO_03110 1.52e-198 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
HNMJCOBO_03111 1.01e-25 - - - S - - - Protein of unknown function (DUF3813)
HNMJCOBO_03112 9.69e-94 ipi - - S - - - Intracellular proteinase inhibitor
HNMJCOBO_03113 2.29e-189 yitT - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
HNMJCOBO_03114 9.13e-202 yitS - - S - - - protein conserved in bacteria
HNMJCOBO_03115 0.0 nprB 3.4.24.28 - E ko:K01400,ko:K08777 ko02024,map02024 ko00000,ko00001,ko01000,ko01002 Peptidase M4
HNMJCOBO_03116 4.59e-59 yitR - - S - - - Domain of unknown function (DUF3784)
HNMJCOBO_03117 7.76e-123 - - - - - - - -
HNMJCOBO_03118 2.08e-77 - - - K - - - Transcriptional regulator PadR-like family
HNMJCOBO_03119 3.29e-127 - - - S - - - Sporulation delaying protein SdpA
HNMJCOBO_03120 1.17e-217 - - - - - - - -
HNMJCOBO_03121 4.16e-122 - - - - - - - -
HNMJCOBO_03122 2.75e-204 yitL - - S ko:K00243 - ko00000 protein conserved in bacteria
HNMJCOBO_03123 1.75e-76 yitK - - S ko:K09767 - ko00000 Belongs to the UPF0234 family
HNMJCOBO_03124 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HNMJCOBO_03125 3.34e-106 - - - S - - - Acetyltransferase (GNAT) domain
HNMJCOBO_03126 1.85e-205 yitH - - K - - - Acetyltransferase (GNAT) domain
HNMJCOBO_03127 4.1e-291 yitG - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
HNMJCOBO_03128 2.14e-283 yitF 5.5.1.27 - M ko:K18983 ko00053,map00053 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
HNMJCOBO_03129 6.62e-140 yitE - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
HNMJCOBO_03130 1.75e-179 yitD 4.4.1.19 - S ko:K08097 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko00002,ko01000 synthase
HNMJCOBO_03131 8.32e-157 - 3.1.3.71 - H ko:K05979 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the ComB family
HNMJCOBO_03132 5.29e-182 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
HNMJCOBO_03133 6.53e-294 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
HNMJCOBO_03134 4.75e-144 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
HNMJCOBO_03135 6.44e-199 yisY 1.11.1.10 - I ko:K00433 - ko00000,ko01000 hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HNMJCOBO_03136 2.15e-96 yisX - - S - - - Pentapeptide repeats (9 copies)
HNMJCOBO_03137 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HNMJCOBO_03138 1.09e-139 argO - - S ko:K06895 - ko00000,ko02000 Lysine exporter protein LysE YggA
HNMJCOBO_03139 7.28e-122 yisT - - S - - - DinB family
HNMJCOBO_03140 9.72e-254 yisS 1.1.1.18, 1.1.1.369, 1.1.1.370 - S ko:K00010,ko:K16043 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
HNMJCOBO_03141 1.83e-235 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
HNMJCOBO_03142 1.41e-207 yisR - - K - - - Transcriptional regulator
HNMJCOBO_03143 1.01e-310 yisQ - - V - - - Mate efflux family protein
HNMJCOBO_03144 6.82e-193 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 phytoene
HNMJCOBO_03145 1.85e-115 yizA - - S - - - Damage-inducible protein DinB
HNMJCOBO_03146 0.0 asnO 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
HNMJCOBO_03147 4.12e-129 yisN - - S - - - Protein of unknown function (DUF2777)
HNMJCOBO_03148 0.0 wprA - - O ko:K13274 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
HNMJCOBO_03149 1.02e-74 yisL - - S - - - UPF0344 protein
HNMJCOBO_03150 1.08e-218 yisK - - Q - - - COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
HNMJCOBO_03151 4.62e-223 cotH - - M ko:K06330 - ko00000 Spore Coat
HNMJCOBO_03152 1.52e-32 yisI - - S - - - Spo0E like sporulation regulatory protein
HNMJCOBO_03153 1.82e-45 gerPA - - S ko:K06299 - ko00000 Spore germination protein
HNMJCOBO_03154 1.76e-47 gerPB - - S ko:K06300 - ko00000 cell differentiation
HNMJCOBO_03155 8.23e-93 gerPC - - S ko:K06301 - ko00000 Spore germination protein
HNMJCOBO_03156 7.36e-34 gerPD - - S ko:K06302 - ko00000 Spore germination protein
HNMJCOBO_03157 4.08e-88 gerPE - - S ko:K06303 - ko00000 Spore germination protein GerPE
HNMJCOBO_03158 3.3e-43 gerPF - - S ko:K06299,ko:K06304 - ko00000 Spore germination protein gerPA/gerPF
HNMJCOBO_03159 7.78e-66 yisB - - V - - - COG1403 Restriction endonuclease
HNMJCOBO_03160 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 COG0419 ATPase involved in DNA repair
HNMJCOBO_03161 4.87e-281 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HNMJCOBO_03162 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
HNMJCOBO_03163 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 ATP-dependent helicase deoxyribonuclease subunit B
HNMJCOBO_03164 5.38e-101 yhjR - - S - - - Rubrerythrin
HNMJCOBO_03165 0.0 - - - S - - - Sugar transport-related sRNA regulator N-term
HNMJCOBO_03166 1.73e-270 - - - EGP - - - Transmembrane secretion effector
HNMJCOBO_03167 4.14e-258 yhjN - - S ko:K07120 - ko00000 membrane
HNMJCOBO_03168 5.09e-238 yhjM - - K - - - Transcriptional regulator
HNMJCOBO_03169 0.0 - 2.6.1.104 - E ko:K18653 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
HNMJCOBO_03170 3.07e-204 ntdB 3.1.3.24, 3.1.3.92 - S ko:K07024,ko:K18654 ko00500,map00500 ko00000,ko00001,ko01000 Sucrose-6F-phosphate phosphohydrolase
HNMJCOBO_03171 3.27e-256 - 1.1.1.18, 1.1.1.361, 1.1.1.369 - S ko:K00010,ko:K18652 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
HNMJCOBO_03172 4.25e-271 glcP - - G ko:K08174 - ko00000,ko02000 Major Facilitator Superfamily
HNMJCOBO_03173 2.82e-122 yhjH - - K - - - helix_turn_helix multiple antibiotic resistance protein
HNMJCOBO_03174 0.0 yhjG - - CH - - - FAD binding domain
HNMJCOBO_03175 5.12e-117 spsB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HNMJCOBO_03176 4.87e-141 yhjE - - S - - - SNARE associated Golgi protein
HNMJCOBO_03177 2.12e-77 yhjD - - - - - - -
HNMJCOBO_03178 1.61e-36 yhjC - - S - - - Protein of unknown function (DUF3311)
HNMJCOBO_03179 0.0 yhjB - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HNMJCOBO_03180 1.68e-55 yhjA - - S - - - Excalibur calcium-binding domain
HNMJCOBO_03181 1.48e-215 yhxD - - IQ - - - Enoyl-(Acyl carrier protein) reductase
HNMJCOBO_03182 6.29e-141 comK - - K ko:K02250 ko02024,map02024 ko00000,ko00001,ko02044,ko03000 Competence transcription factor
HNMJCOBO_03183 9.84e-45 yhzC - - S - - - IDEAL
HNMJCOBO_03184 7.82e-204 yhxC - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HNMJCOBO_03185 0.0 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
HNMJCOBO_03186 1.85e-260 hemAT - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
HNMJCOBO_03187 8.51e-118 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
HNMJCOBO_03188 0.0 vraA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
HNMJCOBO_03189 8.58e-250 yhfS 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
HNMJCOBO_03190 9.64e-141 yhfR 5.4.2.12 - G ko:K15634,ko:K15640 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
HNMJCOBO_03191 4.59e-222 yhfQ - - M ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
HNMJCOBO_03192 5.66e-231 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Quinone oxidoreductase
HNMJCOBO_03193 1.26e-101 - - - K - - - acetyltransferase
HNMJCOBO_03194 6.91e-260 aprE 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
HNMJCOBO_03195 9.64e-308 yhfN - - O - - - Peptidase M48
HNMJCOBO_03196 2.78e-85 yhfM - - - - - - -
HNMJCOBO_03197 0.0 yhfL 6.2.1.3 - IQ ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
HNMJCOBO_03198 1.82e-144 yhfK - - GM - - - NmrA-like family
HNMJCOBO_03199 1.21e-246 lplJ 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
HNMJCOBO_03200 5.93e-183 yhfI - - S - - - COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
HNMJCOBO_03201 4.77e-289 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HNMJCOBO_03202 3.75e-94 - - - S - - - ASCH
HNMJCOBO_03203 2.68e-253 yhfE - - G - - - peptidase M42
HNMJCOBO_03204 1.61e-178 yhfC - - S - - - Putative membrane peptidase family (DUF2324)
HNMJCOBO_03205 8.77e-237 fabHB 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HNMJCOBO_03206 0.0 yhgE - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
HNMJCOBO_03207 3.49e-133 yhgD - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
HNMJCOBO_03208 0.0 hemY 1.3.3.15, 1.3.3.4 - H ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HNMJCOBO_03209 2.06e-232 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
HNMJCOBO_03210 7.78e-261 hemE 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HNMJCOBO_03211 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
HNMJCOBO_03212 1.31e-118 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
HNMJCOBO_03213 1.33e-23 - - - C - - - Rubrerythrin
HNMJCOBO_03214 8.98e-317 yhfA - - C - - - membrane
HNMJCOBO_03215 4.8e-295 yhaA - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HNMJCOBO_03216 5e-162 ecsC - - S - - - EcsC protein family
HNMJCOBO_03217 3.11e-272 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
HNMJCOBO_03218 2.7e-176 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 transporter (ATP-binding protein)
HNMJCOBO_03219 3.5e-106 hit - - FG ko:K02503 - ko00000,ko04147 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
HNMJCOBO_03220 1.84e-262 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HNMJCOBO_03221 6.32e-104 trpP - - S - - - Tryptophan transporter TrpP
HNMJCOBO_03222 1.74e-54 yhaH - - S - - - YtxH-like protein
HNMJCOBO_03223 4.92e-148 hpr - - K ko:K09682 - ko00000,ko03000 Negative regulator of protease production and sporulation
HNMJCOBO_03224 8.48e-73 yhaI - - S - - - Protein of unknown function (DUF1878)
HNMJCOBO_03225 1.4e-116 yhaK - - S - - - Putative zincin peptidase
HNMJCOBO_03226 2.29e-179 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HNMJCOBO_03227 1.88e-39 yhaL - - S - - - Sporulation protein YhaL
HNMJCOBO_03228 5.22e-228 yhaM - - L ko:K03698 - ko00000,ko01000,ko03019 Shows a 3'-5' exoribonuclease activity
HNMJCOBO_03229 0.0 yhaN - - L - - - AAA domain
HNMJCOBO_03230 9.85e-303 yhaO - - L ko:K03547 - ko00000,ko03400 DNA repair exonuclease
HNMJCOBO_03231 5.14e-272 yhaP - - CP ko:K01992 - ko00000,ko00002,ko02000 COG1668 ABC-type Na efflux pump, permease component
HNMJCOBO_03232 5.56e-215 yhaQ - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HNMJCOBO_03233 2.29e-36 - - - S - - - YhzD-like protein
HNMJCOBO_03234 1.6e-172 yhaR - - I - - - enoyl-CoA hydratase
HNMJCOBO_03236 6.51e-114 - - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
HNMJCOBO_03237 1.85e-267 yhaU - - P ko:K03455 - ko00000 COG0475 Kef-type K transport systems, membrane components
HNMJCOBO_03238 0.0 hemZ - - H - - - coproporphyrinogen III oxidase
HNMJCOBO_03239 8.7e-198 yhaX - - S - - - haloacid dehalogenase-like hydrolase
HNMJCOBO_03240 6.69e-264 yhaZ - - L - - - DNA alkylation repair enzyme
HNMJCOBO_03241 7.46e-72 yheA - - S - - - Belongs to the UPF0342 family
HNMJCOBO_03242 1.51e-261 yheB - - S - - - Belongs to the UPF0754 family
HNMJCOBO_03243 3.37e-276 yheC - - HJ - - - YheC/D like ATP-grasp
HNMJCOBO_03244 0.0 yheD - - HJ - - - YheC/D like ATP-grasp
HNMJCOBO_03245 2.27e-49 yheE - - S - - - Family of unknown function (DUF5342)
HNMJCOBO_03246 1.25e-38 sspB - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
HNMJCOBO_03247 9.49e-143 yheG - - GM - - - NAD(P)H-binding
HNMJCOBO_03248 0.0 yheH - - V ko:K06147,ko:K18217,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
HNMJCOBO_03249 0.0 yheI - - V ko:K18216,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
HNMJCOBO_03250 3.85e-109 nhaX - - T - - - Belongs to the universal stress protein A family
HNMJCOBO_03251 1.32e-305 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter
HNMJCOBO_03252 2.23e-197 dat 2.6.1.21 - E ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
HNMJCOBO_03253 5.7e-200 nodB1 - - G - - - deacetylase
HNMJCOBO_03254 2.93e-180 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
HNMJCOBO_03255 4.51e-260 yhdY - - M ko:K16052 - ko00000,ko02000 Mechanosensitive ion channel
HNMJCOBO_03256 3.7e-09 yhdX - - S - - - Uncharacterized protein YhdX
HNMJCOBO_03257 5.44e-174 yhdW 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
HNMJCOBO_03258 4.1e-87 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HNMJCOBO_03259 2.69e-70 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HNMJCOBO_03260 0.0 yhdT - - P - - - COG1253 Hemolysins and related proteins containing CBS domains
HNMJCOBO_03261 4.37e-285 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
HNMJCOBO_03262 3.44e-97 cueR - - K ko:K11923 - ko00000,ko03000 transcriptional
HNMJCOBO_03263 2.18e-304 yhdP - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
HNMJCOBO_03264 3.9e-143 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HNMJCOBO_03265 6.74e-244 yhdN - - C - - - Aldo keto reductase
HNMJCOBO_03266 3.24e-113 sigM - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HNMJCOBO_03267 6.13e-258 yhdL - - S - - - Sigma factor regulator N-terminal
HNMJCOBO_03268 4.27e-59 yhdK - - S - - - Sigma-M inhibitor protein
HNMJCOBO_03269 1.75e-100 - - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HNMJCOBO_03270 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HNMJCOBO_03271 4.29e-310 yhdH - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HNMJCOBO_03272 8.94e-317 yhdG - - E ko:K03294 - ko00000 amino acid
HNMJCOBO_03273 1.41e-208 yhdF - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HNMJCOBO_03274 5.51e-263 citA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
HNMJCOBO_03275 4.93e-210 citR - - K ko:K19242 - ko00000,ko03000 Transcriptional regulator
HNMJCOBO_03276 1.05e-199 lytE - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
HNMJCOBO_03277 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
HNMJCOBO_03278 0.0 spoVR - - S ko:K06415 - ko00000 Stage V sporulation protein R
HNMJCOBO_03279 5.04e-305 ygxB - - M - - - Conserved TM helix
HNMJCOBO_03280 5.58e-99 nsrR - - K ko:K13771 ko05132,map05132 ko00000,ko00001,ko03000 Transcriptional regulator
HNMJCOBO_03281 1.2e-268 lytF - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
HNMJCOBO_03282 1.25e-72 yhdC - - S - - - Protein of unknown function (DUF3889)
HNMJCOBO_03283 1.65e-51 yhdB - - S - - - YhdB-like protein
HNMJCOBO_03284 5.68e-117 yhdA 1.7.1.6 - S ko:K03206 - ko00000,ko01000 NADPH-dependent FMN reductase
HNMJCOBO_03285 5.68e-148 yhcZ - - K ko:K02479 - ko00000,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HNMJCOBO_03286 2.29e-273 yhcY 2.7.13.3 - T ko:K02480 - ko00000,ko01000,ko01001,ko02022 Histidine kinase
HNMJCOBO_03287 0.0 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
HNMJCOBO_03288 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HNMJCOBO_03289 0.0 glpK 2.7.1.30 - C ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HNMJCOBO_03290 5.7e-196 glpF - - G ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
HNMJCOBO_03291 5.35e-135 glpP - - K ko:K02443 - ko00000,ko03000 Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HNMJCOBO_03292 0.0 yhxA - - E - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HNMJCOBO_03293 0.0 yhcX - - K - - - Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HNMJCOBO_03294 3.04e-155 yhcW - - S ko:K07025 - ko00000 hydrolase
HNMJCOBO_03295 1.76e-90 yhcV - - S - - - COG0517 FOG CBS domain
HNMJCOBO_03296 4.27e-89 yhcU - - S - - - Family of unknown function (DUF5365)
HNMJCOBO_03297 8.26e-219 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
HNMJCOBO_03298 3.9e-138 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
HNMJCOBO_03299 0.0 yhcR 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01081,ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
HNMJCOBO_03300 1.68e-146 yhcQ - - M - - - Spore coat protein
HNMJCOBO_03301 3.96e-227 yhcP - - - - - - -
HNMJCOBO_03302 2.69e-111 yhcN - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HNMJCOBO_03303 3.23e-80 yhcM - - - - - - -
HNMJCOBO_03304 2.62e-301 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HNMJCOBO_03305 2.47e-251 yhcK 2.7.7.65 - T ko:K18967 - ko00000,ko01000,ko02000 COG2199 FOG GGDEF domain
HNMJCOBO_03306 1.34e-195 metQ_3 - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
HNMJCOBO_03307 1.91e-42 cspB - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
HNMJCOBO_03308 3.45e-212 yhcI - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HNMJCOBO_03309 2.16e-211 yhcH - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HNMJCOBO_03310 3.24e-156 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HNMJCOBO_03311 4.78e-79 yhcF - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator
HNMJCOBO_03312 2.92e-69 - - - - - - - -
HNMJCOBO_03313 3.95e-59 yhcC - - - - - - -
HNMJCOBO_03314 4.87e-128 yhcB 1.6.5.2 - S ko:K03809 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 Belongs to the WrbA family
HNMJCOBO_03315 0.0 yhcA - - EGP ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
HNMJCOBO_03316 2.67e-133 yhbJ - - V - - - COG1566 Multidrug resistance efflux pump
HNMJCOBO_03317 1.29e-101 yhbI - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
HNMJCOBO_03318 1.21e-286 yhbH - - S ko:K09786 - ko00000 Belongs to the UPF0229 family
HNMJCOBO_03319 0.0 prkA - - T ko:K07180 - ko00000 Ser protein kinase
HNMJCOBO_03320 4.08e-110 yhbF - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
HNMJCOBO_03321 2.29e-96 yhbE - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
HNMJCOBO_03322 3.4e-143 yhbD - - K - - - Protein of unknown function (DUF4004)
HNMJCOBO_03323 6.53e-113 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HNMJCOBO_03324 4.79e-226 yhbB - - S - - - Putative amidase domain
HNMJCOBO_03325 5.09e-285 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HNMJCOBO_03326 1.92e-147 yhzB - - S - - - B3/4 domain
HNMJCOBO_03328 1.48e-39 - - - K ko:K07729 - ko00000,ko03000 Transcriptional regulator
HNMJCOBO_03329 2.79e-102 ygaO - - - - - - -
HNMJCOBO_03330 4.82e-55 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HNMJCOBO_03332 9.35e-276 ssuD 1.14.14.28, 1.14.14.5 - C ko:K04091,ko:K20938 ko00920,map00920 ko00000,ko00001,ko01000 Catalyzes the desulfonation of aliphatic sulfonates
HNMJCOBO_03333 5.86e-190 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HNMJCOBO_03334 1.78e-219 ssuA - - M ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Sulfonate ABC transporter
HNMJCOBO_03335 4.15e-185 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
HNMJCOBO_03336 0.0 katA 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
HNMJCOBO_03338 0.0 ygaK - - C - - - Berberine and berberine like
HNMJCOBO_03339 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HNMJCOBO_03340 6.95e-173 ygaJ 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
HNMJCOBO_03341 3.88e-37 - - - - - - - -
HNMJCOBO_03342 2.22e-185 spo0M - - S ko:K06377 - ko00000 COG4326 Sporulation control protein
HNMJCOBO_03359 8.23e-215 ygxA - - S - - - Nucleotidyltransferase-like
HNMJCOBO_03360 1.57e-73 ygzB - - S - - - UPF0295 protein
HNMJCOBO_03361 2.37e-104 perR - - P ko:K09825 - ko00000,ko03000 Belongs to the Fur family
HNMJCOBO_03362 1.69e-112 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Peroxiredoxin
HNMJCOBO_03363 5.64e-313 gsaB 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
HNMJCOBO_03364 1.87e-238 ygaE - - S - - - Membrane
HNMJCOBO_03365 0.0 ygaD - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
HNMJCOBO_03366 8.1e-136 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
HNMJCOBO_03367 1.88e-63 ygaB - - S - - - YgaB-like protein
HNMJCOBO_03368 2.35e-14 sspE - - S ko:K06422 - ko00000 Small, acid-soluble spore protein, gamma-type
HNMJCOBO_03369 3.13e-172 fabL 1.3.1.104 - IQ ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HNMJCOBO_03370 1.73e-48 yfhS - - - - - - -
HNMJCOBO_03371 8.47e-268 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific
HNMJCOBO_03372 7.22e-237 yfhP - - S ko:K07038 - ko00000 membrane-bound metal-dependent
HNMJCOBO_03373 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
HNMJCOBO_03374 3.43e-236 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
HNMJCOBO_03375 3.37e-219 yfhM 3.8.1.5 - S ko:K01563 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Alpha beta hydrolase
HNMJCOBO_03376 5.4e-67 yfhL - - S - - - SdpI/YhfL protein family
HNMJCOBO_03377 3.58e-119 yfhK - - T - - - Bacterial SH3 domain homologues
HNMJCOBO_03378 5.19e-59 yfhJ - - S - - - WVELL protein
HNMJCOBO_03379 2.25e-27 sspK - - S ko:K06428 - ko00000 reproduction
HNMJCOBO_03380 2.45e-268 yfhI - - EGP - - - -transporter
HNMJCOBO_03382 4.58e-69 yfhH - - S - - - Protein of unknown function (DUF1811)
HNMJCOBO_03383 3.25e-181 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
HNMJCOBO_03384 1.13e-221 yfhF - - S ko:K07071 - ko00000 nucleoside-diphosphate sugar epimerase
HNMJCOBO_03386 8.86e-35 yfhD - - S - - - YfhD-like protein
HNMJCOBO_03387 2.87e-138 yfhC - - C - - - nitroreductase
HNMJCOBO_03388 7.61e-215 yfhB - - S - - - PhzF family
HNMJCOBO_03389 5.18e-229 yfhA - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HNMJCOBO_03390 1.54e-225 yfiZ - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HNMJCOBO_03391 2.81e-233 yfiY - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
HNMJCOBO_03392 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HNMJCOBO_03393 5.39e-106 yfiV - - K - - - transcriptional
HNMJCOBO_03394 0.0 yfiU - - EGP - - - the major facilitator superfamily
HNMJCOBO_03395 2.41e-129 yfiT - - S - - - Belongs to the metal hydrolase YfiT family
HNMJCOBO_03396 4.51e-281 yfiS - - EGP - - - Major facilitator superfamily
HNMJCOBO_03397 4.18e-141 yfiR - - K - - - Transcriptional regulator
HNMJCOBO_03398 2.29e-253 yfiQ - - G ko:K21462 - ko00000 COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
HNMJCOBO_03399 7.87e-128 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
HNMJCOBO_03400 1.89e-128 padR - - K - - - transcriptional
HNMJCOBO_03401 4.56e-267 - - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
HNMJCOBO_03402 3.66e-274 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
HNMJCOBO_03403 3.35e-218 drrA - - V ko:K01990,ko:K09695 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HNMJCOBO_03404 1.05e-146 yfiK - - KT ko:K02479 - ko00000,ko02022 LuxR family transcriptional regulator
HNMJCOBO_03405 7.54e-276 baeS - - T - - - Histidine kinase
HNMJCOBO_03407 5.17e-295 - - - S - - - Oxidoreductase
HNMJCOBO_03408 5.47e-234 - - - G - - - Xylose isomerase
HNMJCOBO_03409 0.0 yfiG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HNMJCOBO_03410 1.28e-228 - - - K ko:K02099 - ko00000,ko03000 AraC-like ligand binding domain
HNMJCOBO_03411 7.28e-209 yfiE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
HNMJCOBO_03412 2.01e-84 yfiD3 - - S - - - DoxX
HNMJCOBO_03413 0.0 yfiC3 - - V ko:K06147 - ko00000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
HNMJCOBO_03414 0.0 yfiB3 - - V ko:K06147 - ko00000,ko02000 ABC transporter
HNMJCOBO_03415 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HNMJCOBO_03416 7.45e-182 - - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
HNMJCOBO_03417 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HNMJCOBO_03418 5.59e-61 yfjA - - S - - - Belongs to the WXG100 family
HNMJCOBO_03419 1.94e-270 yfjB - - - - - - -
HNMJCOBO_03420 2.5e-185 yfjC - - - - - - -
HNMJCOBO_03421 1.49e-131 yfjD - - S - - - Family of unknown function (DUF5381)
HNMJCOBO_03422 1.53e-104 - - - S - - - Family of unknown function (DUF5381)
HNMJCOBO_03423 7.42e-75 yfjF - - S ko:K09771 - ko00000,ko02000 UPF0060 membrane protein
HNMJCOBO_03424 8.16e-36 sspH - - S ko:K06425 - ko00000 Belongs to the SspH family
HNMJCOBO_03425 0.0 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
HNMJCOBO_03426 0.0 acoL 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HNMJCOBO_03427 2.82e-263 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HNMJCOBO_03428 8.81e-241 acoB - - C ko:K21417 - ko00000,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HNMJCOBO_03429 2.75e-244 acoA - - C ko:K21416 - ko00000,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HNMJCOBO_03431 4.56e-37 yfjM - - S - - - Psort location Cytoplasmic, score
HNMJCOBO_03432 6.18e-237 yfjN - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HNMJCOBO_03433 3e-53 - - - S - - - YfzA-like protein
HNMJCOBO_03434 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HNMJCOBO_03435 1.94e-214 yfjP 3.2.2.21 - L ko:K01247 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HNMJCOBO_03436 7.8e-237 corA - - P ko:K03284 - ko00000,ko02000 Mediates influx of magnesium ions
HNMJCOBO_03437 1.32e-191 yfjR - - I - - - NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
HNMJCOBO_03438 5.95e-197 pdaA - - G ko:K01567 - ko00000,ko01000 deacetylase
HNMJCOBO_03439 3.26e-36 yfjT - - - - - - -
HNMJCOBO_03440 1.76e-283 yfkA - - S - - - YfkB-like domain
HNMJCOBO_03441 1.49e-189 yfkC - - M - - - Mechanosensitive ion channel
HNMJCOBO_03442 3.69e-189 yfkD - - S - - - YfkD-like protein
HNMJCOBO_03443 5.44e-235 cax - - P ko:K07300 - ko00000,ko02000 COG0387 Ca2 H antiporter
HNMJCOBO_03444 3.84e-278 yfkF - - EGP - - - COG0477 Permeases of the major facilitator superfamily
HNMJCOBO_03445 1.6e-182 yihY - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
HNMJCOBO_03446 1.03e-66 yfkI - - S - - - gas vesicle protein
HNMJCOBO_03447 9.78e-107 yfkJ 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HNMJCOBO_03448 7.27e-42 yfkK - - S - - - Belongs to the UPF0435 family
HNMJCOBO_03449 2.53e-265 ydiN3 - - EGP - - - COG0477 Permeases of the major facilitator superfamily
HNMJCOBO_03450 7.78e-114 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
HNMJCOBO_03451 0.0 yfkN 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K01119,ko:K06931,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
HNMJCOBO_03452 6.16e-160 frp - - C - - - nitroreductase
HNMJCOBO_03453 1.24e-172 treR - - K ko:K03486 - ko00000,ko03000 transcriptional
HNMJCOBO_03454 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
HNMJCOBO_03455 0.0 treP 2.7.1.201 - G ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HNMJCOBO_03456 0.0 yfkQ - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
HNMJCOBO_03457 2.28e-271 yfkR - - S ko:K06297,ko:K06308 - ko00000 spore germination
HNMJCOBO_03459 2.19e-249 yfkT - - E ko:K06309 - ko00000 Spore germination protein
HNMJCOBO_03460 0.0 yflA - - E ko:K03310 - ko00000 Sodium alanine symporter
HNMJCOBO_03461 1.89e-87 ydhN1 - - S - - - Domain of unknown function (DUF1992)
HNMJCOBO_03462 0.0 yflE 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
HNMJCOBO_03463 0.0 nagE 2.7.1.193, 2.7.1.199 - G ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
HNMJCOBO_03464 1.14e-178 yflG 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
HNMJCOBO_03465 3.63e-66 yflH - - S - - - Protein of unknown function (DUF3243)
HNMJCOBO_03466 6.9e-27 yflI - - - - - - -
HNMJCOBO_03467 1.1e-25 yflJ - - S - - - Protein of unknown function (DUF2639)
HNMJCOBO_03468 2.51e-159 yflK - - S - - - protein conserved in bacteria
HNMJCOBO_03469 2.54e-60 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
HNMJCOBO_03470 1.43e-277 nos 1.14.14.47 - C ko:K00491 ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the NOS family. Bacterial NOS oxygenase subfamily
HNMJCOBO_03471 7.21e-194 yflN - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
HNMJCOBO_03472 1.53e-287 citM - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
HNMJCOBO_03473 1.97e-230 yflP - - S - - - Tripartite tricarboxylate transporter family receptor
HNMJCOBO_03474 3.96e-154 citT - - T ko:K11638 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
HNMJCOBO_03475 0.0 citS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
HNMJCOBO_03476 0.0 yflS - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
HNMJCOBO_03477 4.95e-307 pel 4.2.2.2 - G ko:K01728 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
HNMJCOBO_03478 1.71e-76 yflT - - S - - - Heat induced stress protein YflT
HNMJCOBO_03479 3.01e-31 - - - S - - - Protein of unknown function (DUF3212)
HNMJCOBO_03480 7.77e-210 yfmC - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
HNMJCOBO_03481 4.72e-220 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HNMJCOBO_03482 2.1e-223 fecD - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HNMJCOBO_03483 1.4e-192 fhuC 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
HNMJCOBO_03484 0.0 pkn1 - - S - - - Sulfatase-modifying factor enzyme 1
HNMJCOBO_03485 3.46e-268 - - - G - - - Major Facilitator Superfamily
HNMJCOBO_03486 4.71e-239 yfmJ - - S ko:K07119 - ko00000 N-terminal domain of oxidoreductase
HNMJCOBO_03487 2.45e-103 yfmK 2.3.1.128 - K ko:K03790 - ko00000,ko01000,ko03009 acetyltransferase
HNMJCOBO_03488 1.71e-262 yfmL - - L - - - COG0513 Superfamily II DNA and RNA helicases
HNMJCOBO_03489 0.0 yheS_1 - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HNMJCOBO_03490 3.59e-265 yfmO - - EGP ko:K08221 - ko00000,ko02000 Major facilitator superfamily
HNMJCOBO_03491 3.54e-90 yfmP - - K ko:K21902 - ko00000,ko03000 transcriptional
HNMJCOBO_03492 6.23e-97 yfmQ - - S - - - Uncharacterised protein from bacillus cereus group
HNMJCOBO_03493 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HNMJCOBO_03494 5.14e-161 yfmS - - NT - - - chemotaxis protein
HNMJCOBO_03495 0.0 yfmT 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HNMJCOBO_03496 3.41e-312 yfnA - - E ko:K03294 - ko00000 amino acid
HNMJCOBO_03497 3.03e-167 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
HNMJCOBO_03498 6.21e-268 fsr - - P ko:K08223 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
HNMJCOBO_03499 2.34e-243 yfnD - - M - - - Nucleotide-diphospho-sugar transferase
HNMJCOBO_03500 2.44e-286 yfnE - - S - - - Glycosyltransferase like family 2
HNMJCOBO_03501 9.79e-232 yfnF - - M - - - Nucleotide-diphospho-sugar transferase
HNMJCOBO_03502 4.79e-220 yfnG 4.2.1.45, 4.2.1.46 - M ko:K01709,ko:K01710 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 dehydratase
HNMJCOBO_03503 2.15e-190 yfnH 2.7.7.33 - JM ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 ko00000,ko00001,ko01000 Nucleotidyl transferase
HNMJCOBO_03504 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
HNMJCOBO_03505 0.0 cypD 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
HNMJCOBO_03506 6.1e-255 yetN - - S - - - Protein of unknown function (DUF3900)
HNMJCOBO_03507 4.77e-270 yetM - - CH - - - FAD binding domain
HNMJCOBO_03508 6.74e-117 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
HNMJCOBO_03509 7.35e-203 - - - EG - - - EamA-like transporter family
HNMJCOBO_03510 2.55e-135 yetJ - - S ko:K06890 - ko00000 Belongs to the BI1 family
HNMJCOBO_03511 3.81e-28 yezD - - S - - - Uncharacterized small protein (DUF2292)
HNMJCOBO_03512 3.32e-181 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HNMJCOBO_03513 2.47e-85 yetH - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HNMJCOBO_03514 4.67e-73 yetG 1.14.99.48 - S ko:K07145 ko00860,ko01110,map00860,map01110 ko00000,ko00001,ko01000 Antibiotic biosynthesis monooxygenase
HNMJCOBO_03515 1.49e-156 yetF - - S - - - membrane
HNMJCOBO_03516 0.0 - 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
HNMJCOBO_03517 7.85e-209 - - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HNMJCOBO_03518 1.01e-227 lplB - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
HNMJCOBO_03519 0.0 lplA - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
HNMJCOBO_03520 0.0 yetA - - - - - - -
HNMJCOBO_03521 0.0 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase activity
HNMJCOBO_03522 7.51e-159 - - - E - - - GDSL-like Lipase/Acylhydrolase
HNMJCOBO_03523 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
HNMJCOBO_03524 0.0 - 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
HNMJCOBO_03525 6.66e-144 - - - S - - - Protein of unknown function, DUF624
HNMJCOBO_03526 7.22e-163 yesU - - S - - - Domain of unknown function (DUF1961)
HNMJCOBO_03527 1.56e-165 - - - E - - - GDSL-like Lipase/Acylhydrolase
HNMJCOBO_03528 0.0 yesS - - K - - - Transcriptional regulator
HNMJCOBO_03529 8e-254 - 3.2.1.172 GH105 S ko:K15532 - ko00000,ko01000 Glycosyl Hydrolase Family 88
HNMJCOBO_03530 1.26e-210 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HNMJCOBO_03531 1.83e-212 yesP - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HNMJCOBO_03532 3.96e-312 yesO - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
HNMJCOBO_03533 2.31e-256 - - - K ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, arabinose operon control protein
HNMJCOBO_03534 0.0 yesM 2.7.13.3 - T ko:K07718 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HNMJCOBO_03535 3.48e-130 yesL - - S - - - Protein of unknown function, DUF624
HNMJCOBO_03537 4.85e-130 yesJ - - K - - - Acetyltransferase (GNAT) family
HNMJCOBO_03538 1.04e-133 cotJC - - P ko:K06334 - ko00000 Spore Coat
HNMJCOBO_03539 2.31e-61 cotJB - - S ko:K06333 - ko00000 CotJB protein
HNMJCOBO_03540 3.8e-60 cotJA - - S ko:K06332 - ko00000 Spore coat associated protein JA (CotJA)
HNMJCOBO_03541 3.52e-195 yesF - - GM - - - NAD(P)H-binding
HNMJCOBO_03542 3.92e-104 yesE - - S ko:K06893 - ko00000 SnoaL-like domain
HNMJCOBO_03543 2.64e-134 dhaR3 - - K ko:K16137 - ko00000,ko03000 Transcriptional regulator
HNMJCOBO_03545 1.09e-162 yeeN - - K - - - transcriptional regulatory protein
HNMJCOBO_03547 1.33e-275 rapH - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Tetratricopeptide repeat
HNMJCOBO_03548 1.42e-245 - 3.4.24.40 - CO ko:K01406 ko01503,map01503 ko00000,ko00001,ko01000,ko01002 amine dehydrogenase activity
HNMJCOBO_03549 0.0 - - - L - - - nucleic acid phosphodiester bond hydrolysis
HNMJCOBO_03550 2.1e-109 - - - S - - - Protein of unknown function, DUF600
HNMJCOBO_03551 4.15e-42 - - - S - - - Colicin immunity protein / pyocin immunity protein
HNMJCOBO_03552 7.48e-05 - - - - - - - -
HNMJCOBO_03553 1.13e-270 yeeC - - P - - - T5orf172
HNMJCOBO_03554 0.0 - - - L - - - DEAD-like helicases superfamily
HNMJCOBO_03555 0.0 yeeA - - V - - - Type II restriction enzyme, methylase subunits
HNMJCOBO_03556 5.61e-71 - - - L - - - Resolvase, N terminal domain
HNMJCOBO_03557 3.63e-127 - - - L - - - Recombinase
HNMJCOBO_03558 0.0 rlmCD 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HNMJCOBO_03559 1.8e-218 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HNMJCOBO_03560 0.0 swrC - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HNMJCOBO_03561 2.93e-201 yerO - - K - - - Transcriptional regulator
HNMJCOBO_03562 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HNMJCOBO_03563 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HNMJCOBO_03564 7.37e-61 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HNMJCOBO_03565 0.0 putP - - E ko:K03307,ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HNMJCOBO_03566 2.29e-160 sapB - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
HNMJCOBO_03567 1.22e-250 yerI - - S - - - homoserine kinase type II (protein kinase fold)
HNMJCOBO_03568 1.77e-281 camS - - S - - - COG4851 Protein involved in sex pheromone biosynthesis
HNMJCOBO_03569 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HNMJCOBO_03570 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
HNMJCOBO_03571 4.48e-161 pcrB - - I ko:K07094 - ko00000,ko01000 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
HNMJCOBO_03572 0.0 yerD 1.4.7.1 - E ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 ko00000,ko00001,ko01000 Belongs to the glutamate synthase family
HNMJCOBO_03573 7.62e-68 yerC - - S - - - protein conserved in bacteria
HNMJCOBO_03574 9.58e-244 yerB - - S - - - Protein of unknown function (DUF3048) C-terminal domain
HNMJCOBO_03575 0.0 yerA 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 adenine deaminase
HNMJCOBO_03576 3.45e-37 - - - S - - - Protein of unknown function (DUF2892)
HNMJCOBO_03577 7.95e-290 - - - E ko:K16263 - ko00000,ko02000 Amino acid permease
HNMJCOBO_03578 5.26e-96 - - - K - - - helix_turn_helix ASNC type
HNMJCOBO_03579 1.7e-299 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
HNMJCOBO_03580 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
HNMJCOBO_03581 8.88e-138 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HNMJCOBO_03582 1.71e-240 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
HNMJCOBO_03583 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HNMJCOBO_03584 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HNMJCOBO_03585 1.15e-167 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HNMJCOBO_03586 3.79e-52 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HNMJCOBO_03587 5.86e-168 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
HNMJCOBO_03588 6.85e-315 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HNMJCOBO_03589 2.79e-273 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HNMJCOBO_03590 9.28e-108 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HNMJCOBO_03591 3.13e-38 yebG - - S - - - NETI protein
HNMJCOBO_03592 2.66e-120 yebE - - S - - - UPF0316 protein
HNMJCOBO_03594 1.95e-163 yebC - - M - - - Membrane
HNMJCOBO_03595 1.7e-283 pbuG - - S ko:K06901 - ko00000,ko02000 permease
HNMJCOBO_03596 0.0 - - - S - - - Domain of unknown function (DUF4179)
HNMJCOBO_03597 7.14e-117 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HNMJCOBO_03598 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
HNMJCOBO_03599 0.0 yebA - - E - - - COG1305 Transglutaminase-like enzymes
HNMJCOBO_03600 2.63e-284 yeaD - - S - - - conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
HNMJCOBO_03601 9.32e-225 yeaC - - S ko:K03924 - ko00000,ko01000 COG0714 MoxR-like ATPases
HNMJCOBO_03602 6.13e-199 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HNMJCOBO_03603 0.0 gabP - - E ko:K11735 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
HNMJCOBO_03604 0.0 cotA 1.16.3.3 - Q ko:K06324 - ko00000,ko01000 multicopper oxidases
HNMJCOBO_03605 4.12e-228 yeaA - - S - - - Protein of unknown function (DUF4003)
HNMJCOBO_03606 4.9e-200 - - - I - - - Alpha/beta hydrolase family
HNMJCOBO_03607 8.2e-48 ydjO - - S - - - Cold-inducible protein YdjO
HNMJCOBO_03609 1.09e-205 ydjN - - U - - - Involved in the tonB-independent uptake of proteins
HNMJCOBO_03610 1.79e-84 ydjM - - M - - - Lytic transglycolase
HNMJCOBO_03611 3.5e-249 ydjL 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
HNMJCOBO_03612 0.0 iolT - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HNMJCOBO_03613 6.51e-247 - - - S - - - Ion transport 2 domain protein
HNMJCOBO_03614 5.98e-202 ydjI - - S - - - virion core protein (lumpy skin disease virus)
HNMJCOBO_03615 2.02e-170 ydjH - - S ko:K06872 - ko00000 COG1512 Beta-propeller domains of methanol dehydrogenase type
HNMJCOBO_03616 2.86e-225 ydjG - - L - - - Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HNMJCOBO_03617 7.61e-148 pspA - - KT ko:K03969 - ko00000 Phage shock protein A
HNMJCOBO_03618 1.04e-221 ydjE 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
HNMJCOBO_03619 0.0 gutP - - G ko:K03292,ko:K16248 - ko00000,ko02000 MFS/sugar transport protein
HNMJCOBO_03620 2.39e-255 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
HNMJCOBO_03621 0.0 gutR - - K ko:K16247 - ko00000,ko03000 NB-ARC domain
HNMJCOBO_03622 2.57e-191 ydjC - - S - - - Abhydrolase domain containing 18
HNMJCOBO_03623 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HNMJCOBO_03624 2.14e-58 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HNMJCOBO_03625 3e-167 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
HNMJCOBO_03626 3.2e-37 ydiK - - S - - - Domain of unknown function (DUF4305)
HNMJCOBO_03627 8.73e-162 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HNMJCOBO_03628 5.48e-31 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HNMJCOBO_03629 2.14e-148 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HNMJCOBO_03630 1.46e-117 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HNMJCOBO_03631 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter
HNMJCOBO_03632 1.34e-240 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HNMJCOBO_03633 1.71e-109 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HNMJCOBO_03634 1.76e-163 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214 Inactive homolog of metal-dependent proteases
HNMJCOBO_03635 7.42e-112 ydiB - - S ko:K06925 - ko00000,ko03016 ATPase or kinase
HNMJCOBO_03636 1.75e-227 thiL 2.7.4.16 - H ko:K00946 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HNMJCOBO_03643 3.44e-202 ydhU - - P ko:K07217 - ko00000 Catalase
HNMJCOBO_03644 3.75e-268 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
HNMJCOBO_03645 5.09e-240 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
HNMJCOBO_03646 2.35e-212 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
HNMJCOBO_03647 7.75e-171 ydhQ - - K ko:K03492 - ko00000,ko03000 UTRA
HNMJCOBO_03648 0.0 ydhP 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HNMJCOBO_03649 2.27e-305 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HNMJCOBO_03650 1.44e-68 ydhN3 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HNMJCOBO_03651 2.29e-64 ydhM 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HNMJCOBO_03652 6.3e-255 ydhL - - EGP ko:K18567 - ko00000,ko02000 COG2814 Arabinose efflux permease
HNMJCOBO_03653 9.44e-129 ydhK - - M - - - Protein of unknown function (DUF1541)
HNMJCOBO_03654 6.11e-169 ydhJ - - S ko:K06885 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
HNMJCOBO_03655 2.49e-41 ydhJ - - S ko:K06885 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
HNMJCOBO_03656 3.5e-104 - - - K - - - Acetyltransferase (GNAT) domain
HNMJCOBO_03658 2.26e-87 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
HNMJCOBO_03659 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
HNMJCOBO_03660 4.11e-161 - - - - - - - -
HNMJCOBO_03661 9.61e-290 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HNMJCOBO_03662 1.73e-307 ydhD - - M - - - Glycosyl hydrolase
HNMJCOBO_03663 5.24e-158 ydhC - - K - - - FCD
HNMJCOBO_03664 1.77e-155 ydhB - - S ko:K07090 - ko00000 membrane transporter protein
HNMJCOBO_03665 2.43e-266 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
HNMJCOBO_03666 1.9e-89 - - - K - - - Winged helix DNA-binding domain
HNMJCOBO_03667 1.84e-146 ydgI - - C - - - nitroreductase
HNMJCOBO_03668 0.0 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
HNMJCOBO_03669 2.06e-104 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
HNMJCOBO_03670 5.94e-118 - - - S - - - DinB family
HNMJCOBO_03671 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
HNMJCOBO_03672 0.0 expZ - - S ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ABC transporter
HNMJCOBO_03673 4.14e-113 yycN - - K - - - Acetyltransferase
HNMJCOBO_03674 6.73e-69 - - - S - - - DoxX-like family
HNMJCOBO_03675 2e-126 ydgC - - K - - - Bacterial regulatory proteins, tetR family
HNMJCOBO_03676 2.19e-56 ydgB - - S - - - Spore germination protein gerPA/gerPF
HNMJCOBO_03677 2.74e-50 ydgA - - S - - - Spore germination protein gerPA/gerPF
HNMJCOBO_03678 8.99e-99 cotP - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
HNMJCOBO_03679 1.05e-158 ydfS - - S - - - Protein of unknown function (DUF421)
HNMJCOBO_03680 6.08e-153 ydfR - - S - - - Protein of unknown function (DUF421)
HNMJCOBO_03682 5.33e-39 - - - - - - - -
HNMJCOBO_03683 2.4e-21 ydgA - - S - - - Spore germination protein gerPA/gerPF
HNMJCOBO_03684 2.1e-71 ydfQ - - CO - - - Thioredoxin
HNMJCOBO_03685 8.02e-84 ydfP - - S ko:K15977 - ko00000 DoxX
HNMJCOBO_03686 1.29e-236 ydfO - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
HNMJCOBO_03687 7.8e-142 ydfN - - C ko:K15976 - ko00000,ko01000 nitroreductase
HNMJCOBO_03688 2.59e-199 ydfM - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HNMJCOBO_03689 2.13e-189 - - - K - - - Bacterial transcription activator, effector binding domain
HNMJCOBO_03690 6.79e-152 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
HNMJCOBO_03691 9.73e-226 - - - S - - - Alpha/beta hydrolase family
HNMJCOBO_03692 0.0 ydfJ - - S ko:K06994,ko:K11625 ko02020,map02020 ko00000,ko00001 drug exporters of the RND superfamily
HNMJCOBO_03693 2.3e-142 ydfI - - K ko:K11624 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HNMJCOBO_03694 4.11e-253 ydfH 2.7.13.3 - T ko:K11623 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HNMJCOBO_03696 1.37e-104 - - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HNMJCOBO_03697 5.24e-159 ydfF - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
HNMJCOBO_03698 5.97e-151 ydfE - - S - - - Flavin reductase like domain
HNMJCOBO_03699 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HNMJCOBO_03700 3.05e-207 - - - EG - - - EamA-like transporter family
HNMJCOBO_03701 8.05e-191 - - - J - - - GNAT acetyltransferase
HNMJCOBO_03702 1.06e-295 arsB - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HNMJCOBO_03703 1.22e-74 arsR - - K ko:K03892,ko:K22043 - ko00000,ko03000 transcriptional
HNMJCOBO_03704 9.96e-135 ydeS - - K - - - Transcriptional regulator
HNMJCOBO_03705 1.96e-257 ydeR - - EGP - - - Uncharacterised MFS-type transporter YbfB
HNMJCOBO_03706 1e-144 ywrO - - S ko:K11748 - ko00000,ko02000 NADPH-quinone reductase (modulator of drug activity B)
HNMJCOBO_03707 2.92e-90 ydeP - - K - - - Transcriptional regulator
HNMJCOBO_03708 4.62e-194 ydeO - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
HNMJCOBO_03709 1.02e-72 - - - K - - - HxlR-like helix-turn-helix
HNMJCOBO_03710 1.37e-134 - - - S ko:K07002 - ko00000 Serine hydrolase
HNMJCOBO_03711 2.49e-95 ydeM1 - - I - - - N-terminal half of MaoC dehydratase
HNMJCOBO_03712 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HNMJCOBO_03713 9.01e-195 ydeK - - EG - - - -transporter
HNMJCOBO_03714 2.44e-110 - - - K - - - Transcriptional regulator C-terminal region
HNMJCOBO_03715 3.3e-19 ptsH - - G ko:K11189 - ko00000,ko02000 PTS HPr component phosphorylation site
HNMJCOBO_03716 2.4e-41 - - - S - - - SNARE associated Golgi protein
HNMJCOBO_03717 3.64e-142 - - - - - - - -
HNMJCOBO_03718 5.75e-135 ydeI - - S - - - Bacteriocin-protection, YdeI or OmpD-Associated
HNMJCOBO_03719 3.21e-70 ydeH - - - - - - -
HNMJCOBO_03720 3.11e-276 ydeG - - EGP - - - Major facilitator superfamily
HNMJCOBO_03721 0.0 - - - K - - - COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HNMJCOBO_03722 7.88e-211 ydeE - - K ko:K13653 - ko00000,ko03000 AraC family transcriptional regulator
HNMJCOBO_03723 2.65e-219 ydeD - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HNMJCOBO_03724 6.25e-213 - - - K - - - AraC-like ligand binding domain
HNMJCOBO_03725 8e-181 gmT1 - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HNMJCOBO_03726 1.7e-101 ydeB - - K ko:K07736 - ko00000,ko03000 Transcription factor
HNMJCOBO_03727 4.22e-41 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock
HNMJCOBO_03728 4.24e-146 ydeA - - S - - - DJ-1/PfpI family
HNMJCOBO_03732 1.21e-52 - - - - - - - -
HNMJCOBO_03733 1.04e-44 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
HNMJCOBO_03734 1.91e-169 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HNMJCOBO_03735 9.99e-59 - - - - - - - -
HNMJCOBO_03736 3.99e-96 - - - J - - - Acetyltransferase (GNAT) domain
HNMJCOBO_03744 1.93e-110 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
HNMJCOBO_03745 0.0 tex - - K ko:K06959 - ko00000 COG2183 Transcriptional accessory protein
HNMJCOBO_03746 7.31e-100 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
HNMJCOBO_03747 1.32e-106 ydcG - - S - - - EVE domain
HNMJCOBO_03751 1.86e-141 rsbX 3.1.3.3 - KT ko:K05518 - ko00000,ko01000,ko03021 Sigma factor PP2C-like phosphatases
HNMJCOBO_03752 1.55e-178 sigB - - K ko:K03090 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HNMJCOBO_03753 2.48e-111 rsbW 2.7.11.1 - F ko:K04757 - ko00000,ko01000,ko01001,ko03021 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
HNMJCOBO_03754 1.34e-68 rsbV - - T ko:K04749 - ko00000,ko03021 Belongs to the anti-sigma-factor antagonist family
HNMJCOBO_03755 1.86e-243 rsbU 3.1.3.3 - KT ko:K07315 - ko00000,ko01000,ko03021 phosphatase
HNMJCOBO_03756 8.56e-90 rsbT 2.7.11.1 - T ko:K17752 - ko00000,ko01000,ko01001,ko03021 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
HNMJCOBO_03757 1.8e-74 rsbS - - T ko:K17762 - ko00000,ko03021 antagonist
HNMJCOBO_03758 2.46e-183 rsbR - - T ko:K17763 - ko00000,ko03021 Positive regulator of sigma-B
HNMJCOBO_03759 4.34e-75 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
HNMJCOBO_03760 9.49e-57 ndoAI - - K ko:K07723 - ko00000,ko02048,ko03000 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
HNMJCOBO_03761 7.21e-282 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HNMJCOBO_03762 4.66e-234 ydcC - - M - - - COG2834 Outer membrane lipoprotein-sorting protein
HNMJCOBO_03763 3.78e-76 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HNMJCOBO_03764 2e-136 ydcA - - S - - - membrane protein (homolog of Drosophila rhomboid)
HNMJCOBO_03765 0.0 ydbT - - S ko:K08981 - ko00000 Membrane
HNMJCOBO_03766 2.12e-107 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
HNMJCOBO_03767 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HNMJCOBO_03768 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HNMJCOBO_03769 3.58e-257 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
HNMJCOBO_03770 4.19e-75 ydbP - - CO - - - Thioredoxin
HNMJCOBO_03771 2.72e-202 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HNMJCOBO_03773 1.14e-26 - - - S - - - Fur-regulated basic protein B
HNMJCOBO_03774 4.31e-279 ydbM - - I - - - acyl-CoA dehydrogenase
HNMJCOBO_03775 9.32e-70 ydbL - - - - - - -
HNMJCOBO_03776 2.99e-159 ydbK - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HNMJCOBO_03777 3.23e-219 ydbJ - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HNMJCOBO_03778 3.25e-231 ydbI - - S - - - AI-2E family transporter
HNMJCOBO_03779 8.93e-290 dctA - - U ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HNMJCOBO_03780 3.39e-155 dctR - - T ko:K02475,ko:K11692 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
HNMJCOBO_03781 0.0 dctS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
HNMJCOBO_03782 7.39e-253 dctB - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
HNMJCOBO_03783 9.11e-197 ydbD - - P ko:K07217 - ko00000 Catalase
HNMJCOBO_03784 4.45e-83 ydbC - - S - - - Domain of unknown function (DUF4937
HNMJCOBO_03785 7.58e-79 ydbB - - G - - - Cupin domain
HNMJCOBO_03786 8.37e-11 gsiB - - S ko:K06884 - ko00000 general stress protein
HNMJCOBO_03787 4.3e-190 ydbA - - P - - - EcsC protein family
HNMJCOBO_03788 2.25e-100 ydaT - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
HNMJCOBO_03789 1.67e-42 ydaS - - S - - - membrane
HNMJCOBO_03790 3.9e-286 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
HNMJCOBO_03791 6.14e-53 - - - - - - - -
HNMJCOBO_03792 0.0 ydaP 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
HNMJCOBO_03793 1.79e-101 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
HNMJCOBO_03794 0.0 ydaO - - E - - - amino acid
HNMJCOBO_03795 0.0 ydaN - - S - - - Bacterial cellulose synthase subunit
HNMJCOBO_03796 1.93e-304 ydaM - - M - - - Glycosyl transferase family group 2
HNMJCOBO_03797 0.0 ydaL - - S - - - Uncharacterized protein conserved in bacteria (DUF2334)
HNMJCOBO_03798 1.14e-195 ydaK - - T - - - Diguanylate cyclase, GGDEF domain
HNMJCOBO_03799 3.08e-267 ydaJ - - M - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
HNMJCOBO_03800 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HNMJCOBO_03801 3.95e-98 lrpC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
HNMJCOBO_03802 3.12e-61 ydzA - - EGP - - - Domain of unknown function (DUF3817)
HNMJCOBO_03803 4.39e-177 amj - - U - - - Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
HNMJCOBO_03804 5.24e-101 ydaG - - S - - - general stress protein
HNMJCOBO_03805 8.32e-128 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HNMJCOBO_03806 2.36e-126 ydaE 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
HNMJCOBO_03807 3.74e-207 ydaD - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HNMJCOBO_03808 1e-127 ydaC - - Q - - - Methyltransferase domain
HNMJCOBO_03809 0.0 ydaB - - IQ - - - acyl-CoA ligase
HNMJCOBO_03810 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 transcriptional regulator, MtlR
HNMJCOBO_03811 3.26e-224 ycsN - - S - - - Oxidoreductase
HNMJCOBO_03812 0.0 pbpC 3.4.16.4 - M ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 Penicillin-binding Protein
HNMJCOBO_03813 7.67e-66 yczJ - - S - - - biosynthesis
HNMJCOBO_03815 4.18e-154 ycsK - - E - - - anatomical structure formation involved in morphogenesis
HNMJCOBO_03816 3.8e-171 kipR - - K - - - Transcriptional regulator
HNMJCOBO_03817 1.99e-238 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
HNMJCOBO_03818 2.4e-171 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
HNMJCOBO_03819 4.05e-189 ycsI - - S - - - Belongs to the D-glutamate cyclase family
HNMJCOBO_03820 1.32e-271 ycsG - - P - - - COG1914 Mn2 and Fe2 transporters of the NRAMP family
HNMJCOBO_03821 9.39e-182 ycsF - - S ko:K07160 - ko00000 Belongs to the UPF0271 (lamB) family
HNMJCOBO_03822 1.9e-177 ycsE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
HNMJCOBO_03824 2.29e-88 ycsD 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
HNMJCOBO_03825 2.64e-147 - - - Q - - - COG0412 Dienelactone hydrolase and related enzymes
HNMJCOBO_03826 6.21e-97 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HNMJCOBO_03828 1.01e-256 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Tartrate dehydrogenase
HNMJCOBO_03829 3.77e-269 mtlD 1.1.1.17 - G ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 COG0246 Mannitol-1-phosphate altronate dehydrogenases
HNMJCOBO_03830 8.3e-95 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
HNMJCOBO_03831 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG2213 Phosphotransferase system, mannitol-specific IIBC component
HNMJCOBO_03832 1.34e-74 - - - - - - - -
HNMJCOBO_03833 5.18e-139 ycnK - - K ko:K21601 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
HNMJCOBO_03834 0.0 ycnJ - - P ko:K14166 - ko00000,ko02000 protein, homolog of Cu resistance protein CopC
HNMJCOBO_03835 3.05e-138 ycnI - - S - - - protein conserved in bacteria
HNMJCOBO_03836 5.9e-187 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HNMJCOBO_03837 3.37e-190 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
HNMJCOBO_03838 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HNMJCOBO_03839 7.68e-310 gabT 2.6.1.19, 2.6.1.22 - E ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HNMJCOBO_03840 0.0 gabR - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HNMJCOBO_03841 6.51e-69 yczG - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
HNMJCOBO_03842 1.68e-60 ycnE - - S - - - Monooxygenase
HNMJCOBO_03843 2.12e-174 - 1.5.1.39 - C ko:K10678,ko:K19286 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 ko00000,ko00001,ko01000 Oxidoreductase
HNMJCOBO_03844 2.91e-198 ycnC - - K - - - Transcriptional regulator
HNMJCOBO_03845 0.0 ycnB - - EGP - - - the major facilitator superfamily
HNMJCOBO_03846 4.98e-223 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
HNMJCOBO_03847 5.63e-176 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HNMJCOBO_03848 4.69e-211 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HNMJCOBO_03849 5.42e-206 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HNMJCOBO_03850 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
HNMJCOBO_03851 6.5e-05 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
HNMJCOBO_03852 1.58e-05 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
HNMJCOBO_03854 7.15e-104 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
HNMJCOBO_03855 0.0 yclK - - T - - - HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HNMJCOBO_03856 2.23e-165 yclJ - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HNMJCOBO_03857 2.59e-274 yclI - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease) YclI
HNMJCOBO_03858 2.39e-155 yclH - - P ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
HNMJCOBO_03859 1.09e-252 gerKB - - F ko:K06296 - ko00000,ko02000 Spore germination protein
HNMJCOBO_03860 5.64e-295 gerKC - - S ko:K06297 - ko00000 spore germination
HNMJCOBO_03861 0.0 gerKA - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
HNMJCOBO_03863 0.0 yclG - - M - - - Pectate lyase superfamily protein
HNMJCOBO_03864 0.0 dtpT - - E ko:K03305 - ko00000 amino acid peptide transporter
HNMJCOBO_03865 3.18e-201 yclE 3.4.11.5 - S ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Alpha beta hydrolase
HNMJCOBO_03866 2.32e-104 yclD - - - - - - -
HNMJCOBO_03867 4.02e-52 - 4.1.1.61 - S ko:K21759 ko00627,ko01120,ko01220,map00627,map01120,map01220 ko00000,ko00001,ko01000 response to toxic substance
HNMJCOBO_03868 0.0 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
HNMJCOBO_03869 2.24e-140 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HNMJCOBO_03870 3.59e-207 yclA - - K ko:K21755 - ko00000,ko03000 LysR substrate binding domain
HNMJCOBO_03871 1.23e-187 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
HNMJCOBO_03872 4.6e-157 tcyB - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
HNMJCOBO_03873 7.11e-172 tcyC - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
HNMJCOBO_03874 3.04e-148 yczE - - S ko:K07149 - ko00000 membrane
HNMJCOBO_03875 1.37e-144 sfp - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
HNMJCOBO_03876 0.0 ycxD - - K - - - GntR family transcriptional regulator
HNMJCOBO_03877 1.77e-209 ycxC - - EG - - - EamA-like transporter family
HNMJCOBO_03878 1.61e-126 - - - S - - - YcxB-like protein
HNMJCOBO_03879 1.38e-291 - - - EGP - - - Major Facilitator Superfamily
HNMJCOBO_03880 1.63e-179 srfAD - - Q ko:K15657 ko02024,map02024 ko00000,ko00001,ko01008 thioesterase
HNMJCOBO_03881 0.0 srfAC - - Q ko:K15656,ko:K16121 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 COG1020 Non-ribosomal peptide synthetase modules and related proteins
HNMJCOBO_03882 0.0 srfAB - - Q ko:K15654,ko:K15655,ko:K16120 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HNMJCOBO_03883 0.0 srfAA - - Q ko:K15654,ko:K15655,ko:K16119 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HNMJCOBO_03884 2.47e-85 hxlR - - K - - - transcriptional
HNMJCOBO_03885 2.39e-138 hxlA 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 3-hexulose-6-phosphate synthase
HNMJCOBO_03886 7.65e-125 hxlB 5.3.1.27 - G ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
HNMJCOBO_03887 4.34e-267 tlpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
HNMJCOBO_03888 3.23e-99 nucA - - M - - - Deoxyribonuclease NucA/NucB
HNMJCOBO_03889 4.78e-91 nin - - S - - - Competence protein J (ComJ)
HNMJCOBO_03890 0.0 yckE 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HNMJCOBO_03891 1.01e-68 yckD - - S - - - Protein of unknown function (DUF2680)
HNMJCOBO_03892 2.83e-99 yckC - - S - - - membrane
HNMJCOBO_03895 7.26e-185 yckB - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
HNMJCOBO_03896 1.22e-148 yckA - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
HNMJCOBO_03897 3.09e-287 yciC - - S - - - GTPases (G3E family)
HNMJCOBO_03898 2.56e-141 - - - M - - - ErfK YbiS YcfS YnhG
HNMJCOBO_03899 1.05e-222 folE2 3.5.4.16 - S ko:K09007 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Converts GTP to 7,8-dihydroneopterin triphosphate
HNMJCOBO_03900 5.51e-283 nasA - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
HNMJCOBO_03901 0.0 nasB 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Assimilatory nitrate reductase (electron transfer subunit)
HNMJCOBO_03902 0.0 nasC - - C ko:K00372 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HNMJCOBO_03903 0.0 nasD 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HNMJCOBO_03904 1.2e-74 nasE 1.7.1.15 - P ko:K00363 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Nitrite reductase
HNMJCOBO_03905 0.0 nasF 2.1.1.107, 4.2.1.75 - H ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
HNMJCOBO_03906 8.9e-247 ycgT 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
HNMJCOBO_03907 4.74e-209 ycgS - - I - - - alpha/beta hydrolase fold
HNMJCOBO_03908 3.19e-187 ycgR - - S ko:K07089 - ko00000 permeases
HNMJCOBO_03909 3.82e-195 ycgQ - - S ko:K08986 - ko00000 membrane
HNMJCOBO_03910 3.92e-288 ycgP - - QT - - - COG2508 Regulator of polyketide synthase expression
HNMJCOBO_03911 2.64e-316 putP - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HNMJCOBO_03912 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
HNMJCOBO_03913 3.63e-218 ycgM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
HNMJCOBO_03914 7.76e-187 ycgL - - S ko:K07074 - ko00000 Predicted nucleotidyltransferase
HNMJCOBO_03915 1.15e-233 cah 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 Acetyl xylan esterase (AXE1)
HNMJCOBO_03916 2.05e-230 ycgK - - K ko:K04761 ko02026,map02026 ko00000,ko00001,ko03000 LysR substrate binding domain
HNMJCOBO_03917 1.29e-186 - - - Q - - - ubiE/COQ5 methyltransferase family
HNMJCOBO_03918 1.05e-136 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HNMJCOBO_03919 1.31e-140 tmrB - - S - - - AAA domain
HNMJCOBO_03920 1.83e-191 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HNMJCOBO_03921 7.6e-145 ycgI - - S ko:K09967 - ko00000 Domain of unknown function (DUF1989)
HNMJCOBO_03922 1.96e-315 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
HNMJCOBO_03923 2.52e-193 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
HNMJCOBO_03924 6.42e-147 ycgF - - E - - - Lysine exporter protein LysE YggA
HNMJCOBO_03925 3.7e-101 ycgE - - K - - - helix_turn_helix multiple antibiotic resistance protein
HNMJCOBO_03926 0.0 mdr - - EGP - - - the major facilitator superfamily
HNMJCOBO_03927 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
HNMJCOBO_03928 1.19e-232 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
HNMJCOBO_03929 0.0 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
HNMJCOBO_03930 2.72e-105 ycgB - - - - - - -
HNMJCOBO_03931 0.0 ycgA - - S - - - Membrane
HNMJCOBO_03932 2.5e-279 amhX - - S ko:K14665 - ko00000,ko01000,ko01002 amidohydrolase
HNMJCOBO_03933 2.01e-210 opuAC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
HNMJCOBO_03934 2.1e-186 opuAB - - P ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
HNMJCOBO_03935 8.99e-293 opuAA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
HNMJCOBO_03936 4.82e-61 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
HNMJCOBO_03937 1.17e-267 - - - EGP - - - Uncharacterised MFS-type transporter YbfB
HNMJCOBO_03938 2.32e-279 yceI - - P ko:K08369 - ko00000,ko02000 Uncharacterised MFS-type transporter YbfB
HNMJCOBO_03939 2.96e-245 yceH - - P - - - Belongs to the TelA family
HNMJCOBO_03940 0.0 yceG - - S - - - Putative component of 'biosynthetic module'
HNMJCOBO_03941 4.1e-176 yceF - - P ko:K05794 - ko00000 Protein of unknown function (DUF475)
HNMJCOBO_03942 4.97e-138 yceE - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
HNMJCOBO_03943 8.9e-137 yceD - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
HNMJCOBO_03944 2.64e-141 yceC 3.5.4.33 - T ko:K11991 - ko00000,ko01000,ko03016 proteins involved in stress response, homologs of TerZ and
HNMJCOBO_03945 9.18e-242 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HNMJCOBO_03946 4.63e-173 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HNMJCOBO_03947 1.99e-170 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HNMJCOBO_03948 1.95e-221 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
HNMJCOBO_03949 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
HNMJCOBO_03950 2.39e-180 - 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
HNMJCOBO_03951 1.42e-248 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
HNMJCOBO_03952 3.91e-125 - - - M ko:K17733 - ko00000,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
HNMJCOBO_03953 0.0 ycdC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HNMJCOBO_03954 0.0 ycdB - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HNMJCOBO_03955 1.35e-241 ycdA - - S - - - Domain of unknown function (DUF5105)
HNMJCOBO_03956 5.83e-223 yccK - - C - - - Aldo keto reductase
HNMJCOBO_03957 9.75e-258 - - - CP ko:K09696 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
HNMJCOBO_03958 5.41e-171 natA 3.6.3.7 - CP ko:K01990,ko:K09697 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
HNMJCOBO_03959 6.86e-163 natR - - T ko:K02477,ko:K11641 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
HNMJCOBO_03960 9.56e-217 natK 2.7.13.3 - T ko:K11640 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
HNMJCOBO_03961 2.49e-255 yccF - - K ko:K07039 - ko00000 SEC-C motif
HNMJCOBO_03962 4.32e-78 - - - S - - - RDD family
HNMJCOBO_03963 4e-147 - 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
HNMJCOBO_03964 8.74e-260 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
HNMJCOBO_03965 6.54e-132 lmrA - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
HNMJCOBO_03966 2.87e-308 lmrB - - EGP ko:K18926 - ko00000,ko00002,ko02000 the major facilitator superfamily
HNMJCOBO_03967 3.48e-268 ycbU - - E - - - Selenocysteine lyase
HNMJCOBO_03968 2.52e-156 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HNMJCOBO_03969 7.6e-160 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HNMJCOBO_03970 3.12e-38 tatAD - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HNMJCOBO_03971 0.0 phoD 3.1.3.1 - P ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG3540 Phosphodiesterase alkaline phosphatase D
HNMJCOBO_03972 2.7e-174 ycbR - - T - - - vWA found in TerF C terminus
HNMJCOBO_03973 1.82e-102 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
HNMJCOBO_03974 2.21e-76 ycbP - - S - - - Protein of unknown function (DUF2512)
HNMJCOBO_03975 4.25e-150 - - - S - - - ABC-2 family transporter protein
HNMJCOBO_03976 1.66e-216 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HNMJCOBO_03977 1.66e-218 ycbM - - T - - - Histidine kinase
HNMJCOBO_03978 6.64e-162 ycbL - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HNMJCOBO_03979 1.87e-220 eamA1 - - EG - - - spore germination
HNMJCOBO_03980 8.73e-33 rtpA - - K - - - Tryptophan RNA-binding attenuator protein inhibitory protein
HNMJCOBO_03981 4.64e-227 ycbJ - - S ko:K06979 - br01600,ko00000,ko00002,ko01504 Macrolide 2'-phosphotransferase
HNMJCOBO_03982 0.0 garD 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
HNMJCOBO_03983 2.3e-161 ycbG - - K ko:K05799 - ko00000,ko03000 FCD
HNMJCOBO_03984 0.0 gudD 4.2.1.40 - M ko:K01706 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
HNMJCOBO_03985 0.0 gudP - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
HNMJCOBO_03986 0.0 ycbD - - C ko:K22187 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HNMJCOBO_03987 4.1e-222 ycbC 4.2.1.41 - EM ko:K01707 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 5-dehydro-4-deoxyglucarate dehydratase activity
HNMJCOBO_03988 1.72e-217 glnL - - T ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Regulator
HNMJCOBO_03989 2.05e-293 glnJ 2.7.13.3 - T ko:K07717 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HNMJCOBO_03990 4.35e-238 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
HNMJCOBO_03991 0.0 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
HNMJCOBO_03992 2.23e-234 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine
HNMJCOBO_03993 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
HNMJCOBO_03994 9.84e-261 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
HNMJCOBO_03996 2.91e-165 - - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
HNMJCOBO_03997 7.72e-177 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HNMJCOBO_03998 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HNMJCOBO_03999 6.04e-273 gltP - - C ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HNMJCOBO_04000 1.16e-244 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
HNMJCOBO_04001 5.14e-214 ybfP - - K ko:K13653 - ko00000,ko03000 Transcriptional regulator
HNMJCOBO_04002 0.0 - - - S ko:K06880 - ko00000,ko01000,ko01504 Erythromycin esterase
HNMJCOBO_04003 2.25e-59 ybfN - - - - - - -
HNMJCOBO_04004 6.15e-190 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
HNMJCOBO_04005 7.07e-112 ybfM - - S - - - SNARE associated Golgi protein
HNMJCOBO_04006 5.67e-123 pssA 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HNMJCOBO_04007 4.76e-215 - - - S - - - Alpha/beta hydrolase family
HNMJCOBO_04009 3.4e-228 mpr - - M - - - Belongs to the peptidase S1B family
HNMJCOBO_04010 1.95e-272 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HNMJCOBO_04011 6.07e-187 ybfI - - K - - - AraC-like ligand binding domain
HNMJCOBO_04012 1.51e-207 ybfH - - EG - - - EamA-like transporter family
HNMJCOBO_04013 0.0 ybfG - - M - - - Domain of unknown function (DUF1906)
HNMJCOBO_04015 2.36e-287 ybfB - - G - - - COG0477 Permeases of the major facilitator superfamily
HNMJCOBO_04016 8.93e-220 ybfA - - K - - - FR47-like protein
HNMJCOBO_04017 3.57e-47 - - - S - - - Protein of unknown function (DUF2651)
HNMJCOBO_04018 0.0 glpT - - G ko:K02445 - ko00000,ko02000 -transporter
HNMJCOBO_04019 7.3e-213 glpQ 3.1.3.1, 3.1.4.46 - C ko:K01113,ko:K01126 ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 glycerophosphoryl diester phosphodiesterase
HNMJCOBO_04020 0.0 ybeC - - E - - - amino acid
HNMJCOBO_04021 1.11e-54 ybyB - - - - - - -
HNMJCOBO_04022 9.97e-317 cypC 1.11.2.4 - Q ko:K15629 - ko00000,ko00199,ko01000 Cytochrome P450
HNMJCOBO_04023 3.86e-195 ybxI 3.5.2.6 - V ko:K17838 ko01501,map01501 ko00000,ko00001,ko01000 beta-lactamase
HNMJCOBO_04024 6.92e-41 ybxH - - S - - - Family of unknown function (DUF5370)
HNMJCOBO_04025 5.46e-51 csgA - - S - - - Sigma-G-dependent sporulation-specific SASP protein
HNMJCOBO_04026 0.0 ybxG - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
HNMJCOBO_04027 1.62e-276 ybdO - - S - - - Domain of unknown function (DUF4885)
HNMJCOBO_04028 3.67e-193 ybdN - - - - - - -
HNMJCOBO_04029 2.49e-181 ybdM 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 Protein tyrosine kinase
HNMJCOBO_04031 4.12e-221 - - - T - - - His Kinase A (phospho-acceptor) domain
HNMJCOBO_04032 2.93e-159 - - - T ko:K02483 - ko00000,ko02022 Transcriptional regulatory protein, C terminal
HNMJCOBO_04033 8.07e-233 - - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HNMJCOBO_04034 5.88e-103 - - - CO - - - Thioredoxin-like domain
HNMJCOBO_04035 3.88e-118 - - - C - - - HEAT repeats
HNMJCOBO_04036 3.99e-313 skfF - - S - - - ABC transporter
HNMJCOBO_04037 8.07e-174 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HNMJCOBO_04038 0.0 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
HNMJCOBO_04039 7.24e-304 - - - J - - - 4Fe-4S single cluster domain
HNMJCOBO_04041 1.14e-258 ybcL - - EGP ko:K08164 - ko00000,ko02000 COG2814 Arabinose efflux permease
HNMJCOBO_04042 9.45e-67 - - - K - - - Helix-turn-helix domain
HNMJCOBO_04043 3.6e-80 ybcI - - S - - - Uncharacterized conserved protein (DUF2294)
HNMJCOBO_04044 5.59e-64 - - - - - - - -
HNMJCOBO_04045 2.51e-125 ybcF - - P - - - carbonic anhydrase
HNMJCOBO_04046 0.0 ybcC - - S ko:K09822 - ko00000 Belongs to the UPF0753 family
HNMJCOBO_04047 0.0 ndhF 1.6.5.3 - CP ko:K05577 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HNMJCOBO_04048 4.49e-130 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HNMJCOBO_04049 2.25e-157 adaA - - K ko:K13530 - ko00000,ko01000,ko03000,ko03400 Transcriptional regulator
HNMJCOBO_04050 3.67e-227 alkA 3.2.2.21 - L ko:K01247,ko:K13529 ko03410,map03410 ko00000,ko00001,ko01000,ko03000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HNMJCOBO_04051 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HNMJCOBO_04052 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HNMJCOBO_04053 4.16e-292 ybbR - - S - - - protein conserved in bacteria
HNMJCOBO_04054 5.43e-189 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HNMJCOBO_04055 2.73e-152 rsiW - - K - - - Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
HNMJCOBO_04056 1.6e-127 sigW - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HNMJCOBO_04062 4.19e-101 ybbK - - S - - - Protein of unknown function (DUF523)
HNMJCOBO_04063 1.55e-114 ybbJ - - J - - - acetyltransferase
HNMJCOBO_04064 4.04e-211 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HNMJCOBO_04065 3.82e-194 ybbH - - K - - - transcriptional
HNMJCOBO_04066 7.29e-304 ybbF 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HNMJCOBO_04067 0.0 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the UPF0214 family
HNMJCOBO_04068 0.0 ybbD 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
HNMJCOBO_04069 3.6e-306 ybbC - - S - - - protein conserved in bacteria
HNMJCOBO_04070 0.0 ybbB - - K ko:K21701 - ko00000,ko03000 COG2207 AraC-type DNA-binding domain-containing proteins
HNMJCOBO_04071 9.23e-219 feuA - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Iron-uptake system-binding protein
HNMJCOBO_04072 2.88e-226 feuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HNMJCOBO_04073 3.51e-228 feuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HNMJCOBO_04074 4.01e-184 ybbA - - S ko:K07017 - ko00000 Putative esterase
HNMJCOBO_04075 3.47e-205 ybaS - - S - - - Na -dependent transporter
HNMJCOBO_04077 0.0 ybaR - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
HNMJCOBO_04078 4.31e-181 pdaB - - G - - - Polysaccharide deacetylase
HNMJCOBO_04079 5.95e-133 kbaA - - S ko:K06349 - ko00000 Involved in the activation of the KinB signaling pathway of sporulation
HNMJCOBO_04080 1.04e-122 gerD - - - ko:K06294 - ko00000 -
HNMJCOBO_04081 1.1e-255 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HNMJCOBO_04082 9.05e-170 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
HNMJCOBO_04083 2.54e-91 ybaK - - S - - - Protein of unknown function (DUF2521)
HNMJCOBO_04084 6.15e-186 ybaJ - - Q - - - Methyltransferase domain
HNMJCOBO_04085 4.28e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
HNMJCOBO_04086 1.13e-102 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HNMJCOBO_04087 6.15e-182 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HNMJCOBO_04088 1.6e-177 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HNMJCOBO_04089 2.69e-197 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HNMJCOBO_04090 7.5e-200 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HNMJCOBO_04091 4.27e-77 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
HNMJCOBO_04092 7.01e-217 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HNMJCOBO_04093 3.24e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HNMJCOBO_04094 1.09e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HNMJCOBO_04095 2.45e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
HNMJCOBO_04096 2.92e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HNMJCOBO_04097 2.32e-182 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
HNMJCOBO_04098 6.17e-158 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HNMJCOBO_04099 5.7e-298 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HNMJCOBO_04100 7.32e-95 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
HNMJCOBO_04101 1.59e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
HNMJCOBO_04102 9.16e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HNMJCOBO_04103 2.89e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HNMJCOBO_04104 4.47e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HNMJCOBO_04105 3.11e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HNMJCOBO_04106 1.43e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HNMJCOBO_04107 7.72e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HNMJCOBO_04108 1.43e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HNMJCOBO_04109 3.62e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HNMJCOBO_04110 1.64e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HNMJCOBO_04111 1.88e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
HNMJCOBO_04112 1.96e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HNMJCOBO_04113 5.9e-152 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HNMJCOBO_04114 9.23e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HNMJCOBO_04115 2.83e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HNMJCOBO_04116 2.72e-200 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HNMJCOBO_04117 3.27e-58 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HNMJCOBO_04118 7.43e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
HNMJCOBO_04119 7.2e-144 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HNMJCOBO_04120 2.58e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
HNMJCOBO_04121 8.78e-238 ybaC - - S - - - Alpha/beta hydrolase family
HNMJCOBO_04122 2.01e-287 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HNMJCOBO_04123 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HNMJCOBO_04124 4.85e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HNMJCOBO_04125 6.67e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HNMJCOBO_04126 1.99e-44 rplGB - - J ko:K07590 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the eukaryotic ribosomal protein eL8 family
HNMJCOBO_04127 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HNMJCOBO_04128 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HNMJCOBO_04129 5.1e-140 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
HNMJCOBO_04130 2.84e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HNMJCOBO_04131 4.03e-104 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HNMJCOBO_04132 1.82e-162 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HNMJCOBO_04133 3.4e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HNMJCOBO_04134 1.37e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
HNMJCOBO_04135 2.65e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HNMJCOBO_04136 3.27e-149 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
HNMJCOBO_04137 3.31e-114 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
HNMJCOBO_04138 4.29e-174 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HNMJCOBO_04139 3.52e-96 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HNMJCOBO_04140 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
HNMJCOBO_04141 1.91e-152 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Serine acetyltransferase
HNMJCOBO_04142 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HNMJCOBO_04143 6.35e-113 ispF 2.7.7.60, 4.6.1.12 - I ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HNMJCOBO_04144 1.82e-162 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HNMJCOBO_04145 2.57e-252 yacL - - S - - - COG4956 Integral membrane protein (PIN domain superfamily)
HNMJCOBO_04146 3.8e-251 disA 2.7.7.85 - L ko:K07067 - ko00000,ko01000 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
HNMJCOBO_04147 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HNMJCOBO_04148 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
HNMJCOBO_04149 7.74e-257 mcsB 2.7.14.1 - E ko:K19405 - ko00000,ko01000 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
HNMJCOBO_04150 2.76e-65 mcsA - - S ko:K19411 - ko00000 protein with conserved CXXC pairs
HNMJCOBO_04151 8.72e-100 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
HNMJCOBO_04155 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
HNMJCOBO_04156 1.59e-243 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HNMJCOBO_04157 1.81e-41 yazB - - K - - - transcriptional
HNMJCOBO_04158 4.56e-115 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HNMJCOBO_04159 3.8e-80 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HNMJCOBO_04160 3.32e-205 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HNMJCOBO_04161 4.4e-214 pabC 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 4-amino-4-deoxychorismate lyase
HNMJCOBO_04162 3.46e-136 pabA 2.6.1.85 - EH ko:K01664 ko00790,map00790 ko00000,ko00001,ko01000 Anthranilate synthase
HNMJCOBO_04163 0.0 pabB 2.6.1.85 - EH ko:K01665 ko00790,map00790 ko00000,ko00001,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HNMJCOBO_04164 1.54e-217 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
HNMJCOBO_04165 6.68e-196 yacD 5.2.1.8 - O ko:K07533 - ko00000,ko01000,ko03110 peptidyl-prolyl isomerase
HNMJCOBO_04166 9.54e-208 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HNMJCOBO_04167 6.92e-189 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HNMJCOBO_04168 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HNMJCOBO_04169 4.82e-121 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
HNMJCOBO_04170 0.0 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HNMJCOBO_04171 1.15e-234 yabT 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 serine threonine protein kinase
HNMJCOBO_04172 5.61e-168 yabS - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
HNMJCOBO_04173 0.0 spoIIE 3.1.3.16 - KT ko:K06382 - ko00000,ko01000 stage II sporulation protein E
HNMJCOBO_04176 2.49e-82 yabR - - J ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
HNMJCOBO_04177 4.18e-75 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
HNMJCOBO_04178 5.21e-138 yabQ - - S - - - spore cortex biosynthesis protein
HNMJCOBO_04179 1.91e-66 yabP - - S - - - Sporulation protein YabP
HNMJCOBO_04180 4.22e-50 yabO - - J - - - COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
HNMJCOBO_04181 0.0 yabN 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
HNMJCOBO_04182 0.0 yabM - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HNMJCOBO_04183 5.88e-121 spoVT - - K ko:K04769 - ko00000,ko03000 stage V sporulation protein
HNMJCOBO_04184 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HNMJCOBO_04185 6.36e-54 yabK - - S - - - Peptide ABC transporter permease
HNMJCOBO_04186 8.28e-135 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HNMJCOBO_04187 1.45e-136 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HNMJCOBO_04188 1.22e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HNMJCOBO_04189 9e-310 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HNMJCOBO_04190 2.45e-63 spoVG - - D ko:K06412 - ko00000 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
HNMJCOBO_04191 3.45e-83 yabJ 3.5.99.10 - J ko:K09022 - ko00000,ko01000 translation initiation inhibitor, yjgF family
HNMJCOBO_04192 4.66e-196 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
HNMJCOBO_04193 2.34e-207 ispE 2.7.1.148 - I ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HNMJCOBO_04194 3.96e-37 sspF - - S ko:K06423 - ko00000 DNA topological change
HNMJCOBO_04195 5.32e-53 veg - - S - - - protein conserved in bacteria
HNMJCOBO_04196 1.84e-197 yabG - - S ko:K06436 - ko00000 peptidase
HNMJCOBO_04197 1.24e-199 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HNMJCOBO_04198 1.43e-125 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HNMJCOBO_04199 8.28e-278 yabE - - T - - - protein conserved in bacteria
HNMJCOBO_04200 5.9e-184 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD
HNMJCOBO_04201 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HNMJCOBO_04202 1.51e-58 abrB - - K ko:K06284 - ko00000,ko03000 COG2002 Regulators of stationary sporulation gene expression
HNMJCOBO_04203 1.2e-206 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HNMJCOBO_04204 4.19e-65 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
HNMJCOBO_04205 1.14e-177 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Conserved hypothetical protein 95
HNMJCOBO_04206 1.53e-56 yabA - - L - - - Involved in initiation control of chromosome replication
HNMJCOBO_04207 6.33e-189 yaaT - - S - - - stage 0 sporulation protein
HNMJCOBO_04208 2.82e-235 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
HNMJCOBO_04209 1.26e-95 yaaR - - S ko:K09770 - ko00000 protein conserved in bacteria
HNMJCOBO_04210 1.02e-72 yaaQ - - S - - - protein conserved in bacteria
HNMJCOBO_04211 1.63e-146 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HNMJCOBO_04212 0.0 yaaO - - E - - - Orn Lys Arg decarboxylase
HNMJCOBO_04213 4.15e-259 yaaN - - P - - - Belongs to the TelA family
HNMJCOBO_04214 1.56e-131 xpaC - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
HNMJCOBO_04215 2.21e-42 csfB - - S - - - Inhibitor of sigma-G Gin
HNMJCOBO_04216 5.3e-49 bofA - - S ko:K06317 - ko00000 Sigma-K factor-processing regulatory protein BofA
HNMJCOBO_04217 1.55e-42 yaaL - - S - - - Protein of unknown function (DUF2508)
HNMJCOBO_04218 8.53e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HNMJCOBO_04219 8.75e-55 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HNMJCOBO_04220 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HNMJCOBO_04221 6.05e-108 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HNMJCOBO_04222 5.64e-125 yaaI - - Q - - - COG1335 Amidases related to nicotinamidase
HNMJCOBO_04223 7.49e-269 yaaH - - M ko:K06306 - ko00000 Glycoside Hydrolase Family
HNMJCOBO_04224 5.73e-149 dgk 2.7.1.113 - F ko:K15518 ko00230,map00230 ko00000,ko00001,ko01000 Deoxyguanosine kinase
HNMJCOBO_04225 6.17e-158 dck 2.7.1.74, 2.7.1.76 - F ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko01000 Deoxycytidine kinase
HNMJCOBO_04227 1.89e-293 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HNMJCOBO_04228 6.75e-138 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HNMJCOBO_04229 3.7e-202 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HNMJCOBO_04230 3.75e-316 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
HNMJCOBO_04231 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HNMJCOBO_04232 2.6e-233 yaaC - - S - - - YaaC-like Protein
HNMJCOBO_04233 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)