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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HCLPGIIE_00002	0.0	lacZ_17	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase activity
HCLPGIIE_00004	8.5e-259	-	-	-	G	-	-	-	M42 glutamyl aminopeptidase
HCLPGIIE_00006	6.16e-176	-	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	CobB/CobQ-like glutamine amidotransferase domain
HCLPGIIE_00007	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate
HCLPGIIE_00008	2.62e-100	-	-	-	-	-	-	-	-
HCLPGIIE_00009	5.43e-166	-	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	SAICAR synthetase
HCLPGIIE_00010	0.0	-	-	-	K	-	-	-	Transcription elongation factor, N-terminal
HCLPGIIE_00011	0.0	-	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HCLPGIIE_00012	1.17e-310	-	-	-	H	-	-	-	Flavin containing amine oxidoreductase
HCLPGIIE_00013	1.47e-245	-	-	-	-	-	-	-	-
HCLPGIIE_00014	1.59e-245	rgpB	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HCLPGIIE_00015	0.0	ahcY	3.3.1.1	-	H	ko:K01251	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
HCLPGIIE_00016	5.14e-289	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HCLPGIIE_00017	1.36e-214	-	-	-	KQ	-	-	-	Hypothetical methyltransferase
HCLPGIIE_00020	0.0	-	-	-	E	-	-	-	PFAM major facilitator superfamily MFS_1
HCLPGIIE_00021	3.17e-206	-	-	-	G	ko:K06867,ko:K07001	-	ko00000	response to abiotic stimulus
HCLPGIIE_00023	2.04e-293	-	-	-	MU	ko:K15725	-	ko00000,ko02000	efflux transmembrane transporter activity
HCLPGIIE_00024	5.61e-297	czcB	-	-	M	ko:K15727	-	ko00000,ko02000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HCLPGIIE_00029	1.09e-148	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HCLPGIIE_00030	1.67e-249	-	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
HCLPGIIE_00033	1.45e-103	yciA	-	-	I	ko:K10806	ko01040,map01040	ko00000,ko00001,ko01000,ko01004	acyl-coa hydrolase
HCLPGIIE_00034	3.55e-316	hsrA	-	-	EGP	-	-	-	Major facilitator Superfamily
HCLPGIIE_00035	1.45e-282	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
HCLPGIIE_00036	6.76e-235	-	-	-	CH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
HCLPGIIE_00037	1.06e-178	-	-	-	CH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
HCLPGIIE_00038	0.0	-	3.2.1.23	-	G	ko:K01190,ko:K12308	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolases family 35
HCLPGIIE_00039	5.93e-156	-	-	-	C	-	-	-	Nitroreductase family
HCLPGIIE_00040	0.0	-	-	-	E	-	-	-	Transglutaminase-like
HCLPGIIE_00041	1.6e-109	-	-	-	S	-	-	-	Bacterial transferase hexapeptide (six repeats)
HCLPGIIE_00042	6.56e-112	-	-	-	S	ko:K08999	-	ko00000	Bifunctional nuclease
HCLPGIIE_00044	0.0	-	-	-	P	-	-	-	Citrate transporter
HCLPGIIE_00047	8.73e-187	-	-	-	O	ko:K04083	-	ko00000,ko03110	Hsp33 protein
HCLPGIIE_00048	3.48e-119	-	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HCLPGIIE_00049	1.11e-186	-	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
HCLPGIIE_00050	4.76e-245	-	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
HCLPGIIE_00051	4.33e-206	ybfH	-	-	EG	-	-	-	spore germination
HCLPGIIE_00052	2.35e-63	-	-	-	G	-	-	-	Cupin 2, conserved barrel domain protein
HCLPGIIE_00053	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class I (C) catalytic domain
HCLPGIIE_00054	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycoside hydrolase, family 20, catalytic core
HCLPGIIE_00055	0.0	-	-	-	P	-	-	-	Domain of unknown function (DUF4976)
HCLPGIIE_00056	3.15e-231	-	-	-	CO	-	-	-	Thioredoxin-like
HCLPGIIE_00058	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HCLPGIIE_00059	6.21e-39	-	-	-	-	-	-	-	-
HCLPGIIE_00062	4.27e-117	gepA	-	-	K	-	-	-	Phage-associated protein
HCLPGIIE_00063	1.15e-173	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HCLPGIIE_00064	2.41e-135	thiE	2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17	-	H	ko:K00788,ko:K03147,ko:K14153	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HCLPGIIE_00065	4.56e-215	-	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
HCLPGIIE_00066	3.37e-309	-	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Cys/Met metabolism PLP-dependent enzyme
HCLPGIIE_00067	9.25e-103	-	-	-	K	-	-	-	Transcriptional regulator
HCLPGIIE_00068	1.6e-272	-	5.1.1.1	-	M	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HCLPGIIE_00069	0.0	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	defense response to virus
HCLPGIIE_00070	3.63e-184	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	maintenance of DNA repeat elements
HCLPGIIE_00071	1.51e-73	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HCLPGIIE_00072	1.11e-241	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HCLPGIIE_00073	1.03e-248	-	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase
HCLPGIIE_00074	6.16e-216	-	-	-	C	-	-	-	Aldo/keto reductase family
HCLPGIIE_00075	6.66e-91	mltD	-	CBM50	M	ko:K08307,ko:K12204,ko:K19224	-	ko00000,ko01000,ko01002,ko01011,ko02044	LysM domain
HCLPGIIE_00076	1.33e-277	-	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Cell cycle protein
HCLPGIIE_00077	1.12e-266	-	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HCLPGIIE_00078	0.0	murB	-	-	M	-	-	-	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain
HCLPGIIE_00079	2.79e-226	ddl	6.3.2.4	-	M	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	D-ala D-ala ligase N-terminus
HCLPGIIE_00080	2.55e-216	-	-	-	M	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	POTRA domain, FtsQ-type
HCLPGIIE_00081	1.15e-238	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HCLPGIIE_00082	1.92e-238	-	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Ami_3
HCLPGIIE_00083	1.68e-139	-	2.3.1.181	-	H	ko:K03801	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Biotin/lipoate A/B protein ligase family
HCLPGIIE_00084	0.0	-	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Aconitase family (aconitate hydratase)
HCLPGIIE_00085	4.38e-146	-	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Aconitase C-terminal domain
HCLPGIIE_00086	2.89e-273	-	-	-	-	-	-	-	-
HCLPGIIE_00087	0.0	-	-	-	O	-	-	-	Trypsin
HCLPGIIE_00089	1.33e-252	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HCLPGIIE_00090	0.0	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HCLPGIIE_00091	1.76e-153	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HCLPGIIE_00092	3.41e-281	tig	-	-	O	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HCLPGIIE_00093	0.0	-	-	-	M	ko:K07277	-	ko00000,ko02000,ko03029	Surface antigen
HCLPGIIE_00094	1.39e-154	-	1.14.11.27	-	P	ko:K10277	-	ko00000,ko01000,ko03036	peptidyl-arginine hydroxylation
HCLPGIIE_00095	2.6e-231	-	1.5.1.20	-	E	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Methylenetetrahydrofolate reductase
HCLPGIIE_00096	1.96e-168	-	-	-	CO	-	-	-	Protein conserved in bacteria
HCLPGIIE_00098	2.42e-146	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HCLPGIIE_00099	0.0	-	-	-	P	ko:K07239	-	ko00000	AcrB/AcrD/AcrF family
HCLPGIIE_00100	5.31e-50	-	-	-	O	-	-	-	Cytochrome C assembly protein
HCLPGIIE_00102	0.0	-	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	Catalase
HCLPGIIE_00103	1.88e-29	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HCLPGIIE_00105	2.36e-116	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HCLPGIIE_00106	0.0	-	-	-	S	ko:K07037	-	ko00000	7TM receptor with intracellular HD hydrolase
HCLPGIIE_00107	1.22e-246	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HCLPGIIE_00108	2.73e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
HCLPGIIE_00109	2.03e-116	-	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
HCLPGIIE_00110	6.98e-80	-	-	-	FG	ko:K02503	-	ko00000,ko04147	HIT domain
HCLPGIIE_00111	4.2e-242	-	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HCLPGIIE_00112	8.98e-128	aroK	2.7.1.71	-	E	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HCLPGIIE_00113	9.56e-51	-	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Ribosomal protein S16
HCLPGIIE_00116	7.59e-214	-	-	-	L	ko:K03733	-	ko00000,ko03036	Phage integrase, N-terminal SAM-like domain
HCLPGIIE_00117	8.84e-184	-	-	-	DTZ	-	-	-	EF-hand, calcium binding motif
HCLPGIIE_00118	5.64e-66	-	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit
HCLPGIIE_00119	1.39e-282	tgt	2.4.2.29	-	J	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HCLPGIIE_00120	1.22e-150	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Putative methyltransferase
HCLPGIIE_00121	4.32e-174	-	-	-	F	-	-	-	NUDIX domain
HCLPGIIE_00122	0.0	-	-	-	T	-	-	-	pathogenesis
HCLPGIIE_00123	2.25e-91	-	-	-	O	-	-	-	response to oxidative stress
HCLPGIIE_00124	4.92e-288	-	2.3.1.31	-	E	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko01000	alpha/beta hydrolase fold
HCLPGIIE_00125	3.75e-64	-	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L36
HCLPGIIE_00126	0.0	-	2.3.1.241	-	M	ko:K02517	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Glycosyltransferase family 9 (heptosyltransferase)
HCLPGIIE_00127	1.89e-182	-	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	4Fe-4S single cluster domain
HCLPGIIE_00128	0.0	-	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
HCLPGIIE_00129	0.0	-	-	-	M	-	-	-	Glycosyl transferase 4-like domain
HCLPGIIE_00131	1.26e-267	-	2.1.1.72	-	H	ko:K07318	-	ko00000,ko01000,ko02048	PFAM D12 class N6 adenine-specific DNA methyltransferase
HCLPGIIE_00133	3.26e-154	tlyC	-	-	S	ko:K03699	-	ko00000,ko02042	PFAM CBS domain containing protein
HCLPGIIE_00134	1.88e-308	-	-	-	S	-	-	-	PFAM CBS domain containing protein
HCLPGIIE_00135	0.0	-	-	-	C	-	-	-	Cytochrome c554 and c-prime
HCLPGIIE_00136	1.39e-165	-	-	-	CO	-	-	-	Thioredoxin-like
HCLPGIIE_00137	1.1e-159	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HCLPGIIE_00138	2.61e-153	-	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Thiamine monophosphate synthase
HCLPGIIE_00139	4.25e-238	pyrD	1.3.5.2	-	F	ko:K00254	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Dihydroorotate dehydrogenase
HCLPGIIE_00140	0.0	-	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase alpha chain like domain
HCLPGIIE_00141	5.21e-142	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HCLPGIIE_00142	0.0	-	4.1.1.15	-	E	ko:K01580	ko00250,ko00410,ko00430,ko00650,ko01100,ko01110,ko01120,ko02024,ko04727,ko04940,map00250,map00410,map00430,map00650,map01100,map01110,map01120,map02024,map04727,map04940	ko00000,ko00001,ko00002,ko01000	Pyridoxal-dependent decarboxylase conserved domain
HCLPGIIE_00144	0.0	-	-	-	M	-	-	-	Bacterial sugar transferase
HCLPGIIE_00145	8.19e-140	-	-	-	S	-	-	-	RNA recognition motif
HCLPGIIE_00146	3.4e-183	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
HCLPGIIE_00147	0.0	-	-	-	-	-	-	-	-
HCLPGIIE_00149	0.0	-	-	-	V	-	-	-	ABC-2 type transporter
HCLPGIIE_00150	0.0	-	-	-	C	-	-	-	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein
HCLPGIIE_00151	5.47e-202	-	-	-	S	-	-	-	Domain of unknown function (DUF362)
HCLPGIIE_00152	1.37e-131	-	-	-	J	-	-	-	Putative rRNA methylase
HCLPGIIE_00153	1.72e-144	-	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HCLPGIIE_00154	3.73e-195	-	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease/Exonuclease/phosphatase family
HCLPGIIE_00155	2.27e-288	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	NusA-like KH domain
HCLPGIIE_00158	1.69e-170	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HCLPGIIE_00159	1.1e-278	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HCLPGIIE_00160	1.46e-204	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
HCLPGIIE_00161	3.7e-199	-	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Serine acetyltransferase, N-terminal
HCLPGIIE_00162	4.68e-104	-	-	-	S	ko:K15977	-	ko00000	DoxX
HCLPGIIE_00163	1.6e-291	-	4.2.1.129, 5.4.99.17	-	I	ko:K06045	ko00909,ko01110,map00909,map01110	ko00000,ko00001,ko01000	PFAM Prenyltransferase squalene oxidase
HCLPGIIE_00164	1.11e-191	-	-	-	-	-	-	-	-
HCLPGIIE_00165	4.79e-224	-	5.3.1.13	-	M	ko:K06041	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	SIS domain
HCLPGIIE_00166	3.14e-181	-	-	-	H	-	-	-	ThiF family
HCLPGIIE_00167	8.92e-111	-	-	-	U	-	-	-	response to pH
HCLPGIIE_00168	3.37e-222	-	-	-	-	-	-	-	-
HCLPGIIE_00169	2.76e-216	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HCLPGIIE_00171	0.0	-	-	-	G	-	-	-	Raffinose synthase or seed imbibition protein Sip1
HCLPGIIE_00172	1.56e-239	-	-	-	S	-	-	-	COGs COG4299 conserved
HCLPGIIE_00173	8.4e-143	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
HCLPGIIE_00174	0.0	-	3.4.16.4	-	M	ko:K05515	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein dimerisation domain
HCLPGIIE_00175	0.0	-	-	-	-	-	-	-	-
HCLPGIIE_00176	7.19e-209	-	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	ATP synthase A chain
HCLPGIIE_00177	3.32e-11	-	-	-	S	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	PFAM H transporting two-sector ATPase C subunit
HCLPGIIE_00178	1.03e-76	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	ATP synthase B/B' CF(0)
HCLPGIIE_00179	2.53e-83	-	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	ATP synthase delta (OSCP) subunit
HCLPGIIE_00180	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HCLPGIIE_00181	3.54e-198	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HCLPGIIE_00182	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HCLPGIIE_00183	1.97e-87	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HCLPGIIE_00184	3.38e-140	-	-	-	-	-	-	-	-
HCLPGIIE_00185	1.43e-119	sprT	-	-	K	-	-	-	SprT-like family
HCLPGIIE_00186	2.18e-268	-	-	-	S	-	-	-	COGs COG4299 conserved
HCLPGIIE_00187	3.8e-285	-	2.6.1.59	-	M	ko:K02805	-	ko00000,ko01000,ko01007	DegT/DnrJ/EryC1/StrS aminotransferase family
HCLPGIIE_00188	4.56e-110	flmH	2.3.1.57	-	J	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	ko00000,ko00001,ko00002,ko01000	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HCLPGIIE_00189	1.26e-218	-	-	-	M	-	-	-	Glycosyl transferase family 2
HCLPGIIE_00190	3.11e-73	-	-	-	P	ko:K03297,ko:K11741	-	ko00000,ko02000	Multidrug Resistance protein
HCLPGIIE_00191	7.86e-77	-	-	-	P	ko:K03297,ko:K11741	-	ko00000,ko02000	Multidrug Resistance protein
HCLPGIIE_00194	3.49e-133	-	-	-	F	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
HCLPGIIE_00195	0.0	-	2.6.1.62	-	H	ko:K00833	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
HCLPGIIE_00196	1.69e-232	-	2.8.1.6	-	H	ko:K01012	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Biotin and Thiamin Synthesis associated domain
HCLPGIIE_00197	0.0	-	-	-	P	-	-	-	Sulfatase
HCLPGIIE_00198	0.0	-	-	-	M	-	-	-	Bacterial membrane protein, YfhO
HCLPGIIE_00199	4.51e-281	-	-	-	O	ko:K09015	-	ko00000	Uncharacterized protein family (UPF0051)
HCLPGIIE_00200	0.0	-	-	-	O	ko:K09014	-	ko00000	Uncharacterized protein family (UPF0051)
HCLPGIIE_00201	1.02e-178	-	-	-	O	ko:K09013	-	ko00000,ko02000	ATPases associated with a variety of cellular activities
HCLPGIIE_00202	6.78e-100	-	-	-	P	ko:K09825	-	ko00000,ko03000	Ferric uptake regulator family
HCLPGIIE_00203	2.14e-57	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L27 protein
HCLPGIIE_00204	4.81e-163	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
HCLPGIIE_00205	1.88e-135	-	-	-	K	ko:K07735	-	ko00000,ko03000	Uncharacterized ACR, COG1678
HCLPGIIE_00206	1.19e-162	-	-	-	S	ko:K06997	-	ko00000	Alanine racemase, N-terminal domain
HCLPGIIE_00207	0.0	-	-	-	S	-	-	-	50S ribosome-binding GTPase
HCLPGIIE_00208	3.48e-140	-	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	5-formyltetrahydrofolate cyclo-ligase family
HCLPGIIE_00209	2.83e-205	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HCLPGIIE_00210	0.0	-	-	-	E	-	-	-	Peptidase dimerisation domain
HCLPGIIE_00211	1.48e-221	hprK	-	-	T	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr)
HCLPGIIE_00212	8.72e-53	-	-	-	G	ko:K11189	-	ko00000,ko02000	PTS HPr component phosphorylation site
HCLPGIIE_00213	0.0	-	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HCLPGIIE_00214	0.0	-	-	-	P	-	-	-	Sulfatase
HCLPGIIE_00215	1.64e-223	-	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HCLPGIIE_00216	1.45e-93	-	-	-	S	ko:K02426	-	ko00000	Fe-S metabolism associated domain
HCLPGIIE_00218	1.62e-86	-	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Alpha amylase, C-terminal all-beta domain
HCLPGIIE_00221	1.56e-108	ptsN	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770,ko:K02806	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system
HCLPGIIE_00223	1.59e-150	-	-	-	-	-	-	-	-
HCLPGIIE_00224	0.0	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
HCLPGIIE_00226	0.0	-	-	-	MU	ko:K18139	ko01501,ko02024,map01501,map02024	ko00000,ko00001,ko00002,ko01504,ko02000	Outer membrane efflux protein
HCLPGIIE_00227	0.0	-	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HCLPGIIE_00228	2.24e-282	-	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HCLPGIIE_00229	4.61e-120	ngr	-	-	C	-	-	-	Rubrerythrin
HCLPGIIE_00230	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF1705)
HCLPGIIE_00231	0.0	-	-	-	M	-	-	-	Glycosyl Hydrolase Family 88
HCLPGIIE_00232	0.0	-	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Anaerobic ribonucleoside-triphosphate reductase
HCLPGIIE_00233	3.8e-43	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	CTP reductase activity
HCLPGIIE_00234	1.07e-188	-	1.97.1.4	-	O	ko:K04069	-	ko00000,ko01000	Radical SAM superfamily
HCLPGIIE_00235	0.0	-	-	-	P	ko:K14445	-	ko00000,ko02000	Citrate transporter
HCLPGIIE_00236	0.0	-	-	-	T	-	-	-	Histidine kinase
HCLPGIIE_00237	4.64e-111	-	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	cheY-homologous receiver domain
HCLPGIIE_00239	0.0	-	3.6.4.13	-	L	ko:K03578	-	ko00000,ko01000	Oligonucleotide/oligosaccharide-binding (OB)-fold
HCLPGIIE_00240	3.52e-161	-	-	-	P	ko:K03499	-	ko00000,ko02000	TrkA-N domain
HCLPGIIE_00241	0.0	-	-	-	P	-	-	-	Cation transport protein
HCLPGIIE_00243	8.64e-177	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HCLPGIIE_00244	0.0	-	-	-	G	-	-	-	Domain of unknown function (DUF4091)
HCLPGIIE_00245	3.2e-70	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HCLPGIIE_00246	2.19e-100	manC	-	-	S	-	-	-	Cupin domain
HCLPGIIE_00247	0.0	-	1.2.7.1	-	C	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HCLPGIIE_00248	0.0	pckG	4.1.1.32	-	C	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle
HCLPGIIE_00249	9.48e-165	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	PFAM N-acetylmuramoyl-L-alanine amidase family 2
HCLPGIIE_00250	0.0	-	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	RecG wedge domain
HCLPGIIE_00252	0.0	-	-	-	C	ko:K00184	-	ko00000	4Fe-4S dicluster domain
HCLPGIIE_00253	4.18e-178	-	-	-	C	-	-	-	Cytochrome c7 and related cytochrome c
HCLPGIIE_00254	1.44e-313	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HCLPGIIE_00256	1.9e-256	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Iron-containing alcohol dehydrogenase
HCLPGIIE_00258	0.0	gltX	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HCLPGIIE_00259	0.0	kefA	-	-	M	ko:K05802,ko:K22051	-	ko00000,ko02000	cellular water homeostasis
HCLPGIIE_00260	1.78e-97	queF	1.7.1.13	-	S	ko:K09457	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	QueF-like protein
HCLPGIIE_00261	1.02e-159	queC	6.3.4.20	-	F	ko:K06920	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Queuosine biosynthesis protein QueC
HCLPGIIE_00262	9.88e-145	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HCLPGIIE_00263	0.0	-	-	-	J	-	-	-	Beta-Casp domain
HCLPGIIE_00264	1.23e-62	-	-	-	S	-	-	-	Protein of unknown function (DUF1232)
HCLPGIIE_00265	7.12e-159	-	-	-	S	-	-	-	Protein of unknown function (DUF4230)
HCLPGIIE_00266	7.04e-305	-	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Isocitrate/isopropylmalate dehydrogenase
HCLPGIIE_00267	1.79e-267	-	-	-	S	-	-	-	Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units
HCLPGIIE_00268	2.38e-61	-	-	-	E	ko:K07032	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HCLPGIIE_00270	5.19e-263	-	-	-	C	-	-	-	Cytochrome c
HCLPGIIE_00286	2.42e-208	MA20_36650	-	-	EG	-	-	-	spore germination
HCLPGIIE_00287	0.0	-	-	-	S	-	-	-	Alpha-2-macroglobulin family
HCLPGIIE_00288	6.47e-181	-	-	-	S	-	-	-	Alpha-2-macroglobulin family
HCLPGIIE_00289	3.52e-185	-	-	-	C	-	-	-	Iron-containing alcohol dehydrogenase
HCLPGIIE_00290	6.72e-81	-	-	-	C	-	-	-	Iron-containing alcohol dehydrogenase
HCLPGIIE_00292	3.94e-121	-	2.1.1.63	-	L	ko:K00567	-	ko00000,ko01000,ko03400	6-O-methylguanine DNA methyltransferase, DNA binding domain
HCLPGIIE_00295	4.04e-210	-	-	-	-	-	-	-	-
HCLPGIIE_00296	1.09e-149	-	-	-	O	-	-	-	Glycoprotease family
HCLPGIIE_00297	2.89e-272	-	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Citrate synthase, C-terminal domain
HCLPGIIE_00298	2.35e-05	-	-	-	S	ko:K08984	-	ko00000	Predicted membrane protein (DUF2238)
HCLPGIIE_00299	1.57e-111	-	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HCLPGIIE_00300	1.18e-138	-	-	-	L	-	-	-	RNase_H superfamily
HCLPGIIE_00302	6.68e-103	smpB	-	-	O	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HCLPGIIE_00303	3.54e-43	-	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	RNA polymerase activity
HCLPGIIE_00304	6.23e-51	-	5.4.99.20	-	J	ko:K06181	-	ko00000,ko01000,ko03009	RNA pseudouridylate synthase
HCLPGIIE_00305	3.98e-65	-	5.4.99.20	-	J	ko:K06181	-	ko00000,ko01000,ko03009	RNA pseudouridylate synthase
HCLPGIIE_00306	4.74e-210	-	-	-	-	-	-	-	-
HCLPGIIE_00307	6.2e-103	-	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	NDK
HCLPGIIE_00308	4.9e-201	-	-	-	S	-	-	-	Glycosyltransferase like family 2
HCLPGIIE_00309	4.12e-225	-	-	-	M	-	-	-	Glycosyl transferase family 2
HCLPGIIE_00310	3.51e-07	-	-	-	NU	-	-	-	Prokaryotic N-terminal methylation motif
HCLPGIIE_00311	1.2e-283	-	-	-	NU	ko:K02653	-	ko00000,ko02035,ko02044	Type II secretion system (T2SS), protein F
HCLPGIIE_00312	0.0	-	-	-	NU	ko:K02652	-	ko00000,ko02035,ko02044	Type II secretion system (T2SS), protein E, N-terminal domain
HCLPGIIE_00313	2.01e-260	-	-	-	NU	ko:K02652	-	ko00000,ko02035,ko02044	Type II/IV secretion system protein
HCLPGIIE_00314	1.53e-89	-	-	-	NU	ko:K02652	-	ko00000,ko02035,ko02044	Type II/IV secretion system protein
HCLPGIIE_00315	2.97e-244	-	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HCLPGIIE_00316	2.83e-110	-	-	-	S	-	-	-	Control of competence regulator ComK, YlbF/YmcA
HCLPGIIE_00317	6.39e-280	-	2.6.1.1	-	E	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	DegT/DnrJ/EryC1/StrS aminotransferase family
HCLPGIIE_00318	0.0	murJ	-	-	S	ko:K03980	-	ko00000,ko01011,ko02000	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
HCLPGIIE_00319	1.26e-271	-	-	-	IM	-	-	-	Cytidylyltransferase-like
HCLPGIIE_00320	1.74e-157	-	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	Iron/manganese superoxide dismutases, alpha-hairpin domain
HCLPGIIE_00321	0.0	-	-	-	S	-	-	-	Glycosyl hydrolase-like 10
HCLPGIIE_00322	9.28e-170	-	-	-	S	ko:K06898	-	ko00000	AIR carboxylase
HCLPGIIE_00323	1.62e-189	-	-	-	L	ko:K06864	-	ko00000	tRNA processing
HCLPGIIE_00324	2.65e-288	larC	4.99.1.12	-	S	ko:K09121	-	ko00000,ko01000	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
HCLPGIIE_00325	1.07e-238	-	2.5.1.90	-	H	ko:K02523	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Polyprenyl synthetase
HCLPGIIE_00326	0.0	-	-	-	E	ko:K03305	-	ko00000	POT family
HCLPGIIE_00327	0.0	-	5.2.1.8	-	O	ko:K03770	-	ko00000,ko01000,ko03110	PPIC-type PPIASE domain
HCLPGIIE_00328	2.39e-126	-	-	-	S	-	-	-	Pfam:DUF59
HCLPGIIE_00329	8.68e-106	-	-	-	-	-	-	-	-
HCLPGIIE_00331	3.12e-219	-	-	-	E	-	-	-	Domain of unknown function (DUF3472)
HCLPGIIE_00332	2.71e-316	nuoN	1.6.5.3	-	C	ko:K00343	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HCLPGIIE_00333	0.0	-	1.6.5.3	-	C	ko:K00342	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Proton-conducting membrane transporter
HCLPGIIE_00334	0.0	-	1.6.5.3	-	CP	ko:K00341	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus
HCLPGIIE_00335	6.01e-61	nuoK	1.6.5.3	-	C	ko:K00340	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HCLPGIIE_00336	9.96e-20	-	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	RNA pseudouridylate synthase
HCLPGIIE_00337	1.2e-189	-	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	RNA pseudouridylate synthase
HCLPGIIE_00338	1.34e-151	-	1.5.1.34	-	C	ko:K10679	ko00633,ko01120,map00633,map01120	ko00000,ko00001,ko01000	Nitroreductase family
HCLPGIIE_00339	0.0	-	-	-	M	ko:K04744	-	ko00000,ko02000	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
HCLPGIIE_00340	0.0	-	-	-	M	-	-	-	NPCBM/NEW2 domain
HCLPGIIE_00341	0.0	-	-	-	G	-	-	-	Glycogen debranching enzyme
HCLPGIIE_00342	1.83e-231	-	1.1.1.37	-	C	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible oxidation of malate to oxaloacetate
HCLPGIIE_00343	0.0	-	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	UDP binding domain
HCLPGIIE_00347	5.16e-205	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
HCLPGIIE_00348	0.0	-	-	-	M	ko:K09808	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	MacB-like periplasmic core domain
HCLPGIIE_00349	1.48e-189	-	-	-	S	-	-	-	RDD family
HCLPGIIE_00350	5.92e-131	-	2.3.1.129	-	M	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	ko00000,ko00001,ko00002,ko01000,ko01005	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HCLPGIIE_00351	9.06e-168	-	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD-hyrolase-like
HCLPGIIE_00352	4.66e-280	-	-	-	S	ko:K09760	-	ko00000	RmuC family
HCLPGIIE_00353	0.0	-	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Transglycosylase
HCLPGIIE_00354	9.14e-239	-	-	-	O	-	-	-	Trypsin-like peptidase domain
HCLPGIIE_00355	5.64e-275	-	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
HCLPGIIE_00358	2.53e-75	mmyX	5.3.1.12	-	F	ko:K01812,ko:K07149,ko:K16139	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000,ko02000	Psort location Cytoplasmic, score
HCLPGIIE_00359	7.44e-202	mmyX	5.3.1.12	-	F	ko:K01812,ko:K07149,ko:K16139	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000,ko02000	Psort location Cytoplasmic, score
HCLPGIIE_00360	4.08e-112	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Cys-tRNA(Pro) hydrolase activity
HCLPGIIE_00362	3.93e-114	-	-	-	T	ko:K07005	-	ko00000	pyridoxamine 5'-phosphate
HCLPGIIE_00363	1.33e-165	-	-	-	S	-	-	-	Integral membrane protein (intg_mem_TP0381)
HCLPGIIE_00364	5.22e-269	-	-	-	C	-	-	-	NADH:flavin oxidoreductase / NADH oxidase family
HCLPGIIE_00365	4.04e-148	-	4.1.3.27	-	EH	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Peptidase C26
HCLPGIIE_00366	2.55e-247	pabB	2.6.1.85, 4.1.3.27, 4.1.3.38	-	EH	ko:K01665,ko:K03342,ko:K13503,ko:K13950	ko00400,ko00790,ko01100,ko01110,ko01130,ko01230,map00400,map00790,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HCLPGIIE_00367	1.31e-148	-	4.1.3.38	-	E	ko:K02619	ko00790,map00790	ko00000,ko00001,ko01000	branched-chain-amino-acid transaminase activity
HCLPGIIE_00368	3.87e-313	-	5.1.3.8	-	G	ko:K01787	ko00520,map00520	ko00000,ko00001,ko01000	N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
HCLPGIIE_00369	1.38e-223	-	4.1.3.3	-	EM	ko:K01639	ko00520,map00520	ko00000,ko00001,ko01000	Dihydrodipicolinate synthetase family
HCLPGIIE_00370	0.0	-	-	-	-	-	-	-	-
HCLPGIIE_00371	1.47e-193	-	-	-	I	-	-	-	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
HCLPGIIE_00372	0.0	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HCLPGIIE_00373	0.0	glnA	6.3.1.2	-	S	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HCLPGIIE_00374	1.1e-34	-	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L34
HCLPGIIE_00375	1.41e-75	-	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	Ribonuclease P
HCLPGIIE_00376	4.61e-61	-	-	-	S	ko:K08998	-	ko00000	Haemolytic
HCLPGIIE_00377	0.0	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins
HCLPGIIE_00378	0.0	-	1.4.1.13, 1.4.1.14	-	E	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	GXGXG motif
HCLPGIIE_00383	1.68e-158	-	-	-	S	ko:K06911	-	ko00000	Pirin
HCLPGIIE_00384	0.0	-	-	-	M	-	-	-	AsmA-like C-terminal region
HCLPGIIE_00386	1.03e-201	-	-	-	G	-	-	-	Class II Aldolase and Adducin N-terminal domain
HCLPGIIE_00387	0.0	-	2.7.1.51	-	G	ko:K00879	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
HCLPGIIE_00388	0.0	fucI	5.3.1.25, 5.3.1.3	-	G	ko:K01818	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Converts the aldose L-fucose into the corresponding ketose L-fuculose
HCLPGIIE_00389	9.75e-33	-	-	-	G	-	-	-	Major Facilitator Superfamily
HCLPGIIE_00393	1.23e-124	cobU	2.7.1.156, 2.7.7.62, 6.3.5.10	-	H	ko:K02231,ko:K02232	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	cobinamide kinase activity
HCLPGIIE_00394	4.06e-208	-	-	-	G	-	-	-	myo-inosose-2 dehydratase activity
HCLPGIIE_00395	9.36e-172	cobS	2.7.8.26	-	H	ko:K02233	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
HCLPGIIE_00396	2.08e-241	cobT	2.4.2.21	-	H	ko:K00768	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
HCLPGIIE_00397	4.33e-235	cobD	6.3.1.10	-	H	ko:K02227	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
HCLPGIIE_00398	0.0	cobQ	-	-	H	-	-	-	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
HCLPGIIE_00399	0.0	-	-	-	H	ko:K02014	-	ko00000,ko02000	TonB dependent receptor
HCLPGIIE_00402	1.39e-157	-	-	-	S	-	-	-	3D domain
HCLPGIIE_00403	2.07e-149	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HCLPGIIE_00404	9.91e-171	-	-	-	U	ko:K03561	-	ko00000,ko02000	MotA/TolQ/ExbB proton channel family
HCLPGIIE_00405	2.52e-108	aglS	-	-	U	ko:K03559	-	ko00000,ko02000	biopolymer transport protein
HCLPGIIE_00406	2.15e-99	exbD2	-	-	U	ko:K03559	-	ko00000,ko02000	biopolymer transport protein
HCLPGIIE_00407	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
HCLPGIIE_00408	2.87e-190	-	-	-	-	-	-	-	-
HCLPGIIE_00409	2.47e-274	-	-	-	K	-	-	-	sequence-specific DNA binding
HCLPGIIE_00410	0.0	-	-	-	J	ko:K08301	-	ko00000,ko01000,ko03009,ko03019	Ribonuclease E/G family
HCLPGIIE_00411	9.18e-121	-	-	-	-	-	-	-	-
HCLPGIIE_00412	0.0	-	3.2.1.18	GH33	G	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	ko00000,ko00001,ko01000,ko02042	N-terminal domain of BNR-repeat neuraminidase
HCLPGIIE_00413	8.73e-135	-	-	-	K	ko:K03088	-	ko00000,ko03021	ECF sigma factor
HCLPGIIE_00414	7.29e-60	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	negative regulation of transcription, DNA-templated
HCLPGIIE_00415	0.0	copA	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
HCLPGIIE_00416	0.0	-	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	ThiC-associated domain
HCLPGIIE_00417	3.48e-217	ytpP	2.7.1.180, 5.3.4.1	-	CO	ko:K01829,ko:K03671,ko:K03734,ko:K06196	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko01000,ko02000,ko03110	cell redox homeostasis
HCLPGIIE_00418	1.07e-138	-	-	-	K	-	-	-	ECF sigma factor
HCLPGIIE_00421	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class II (D, K and N)
HCLPGIIE_00422	1.02e-187	pppL	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	protein serine/threonine phosphatase activity
HCLPGIIE_00423	4.34e-152	-	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Glycerol-3-phosphate acyltransferase
HCLPGIIE_00424	1.1e-233	gpsA	1.1.1.94	-	C	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
HCLPGIIE_00425	1.01e-100	-	-	-	-	-	-	-	-
HCLPGIIE_00427	7.78e-261	pqqE	-	-	C	ko:K06139	-	ko00000	SMART Elongator protein 3 MiaB NifB
HCLPGIIE_00428	4.95e-309	pqqE	-	-	C	ko:K06139	-	ko00000	SMART Elongator protein 3 MiaB NifB
HCLPGIIE_00429	3.84e-316	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Cys/Met metabolism PLP-dependent enzyme
HCLPGIIE_00430	8.03e-05	-	-	-	-	-	-	-	-
HCLPGIIE_00431	7.18e-298	-	-	-	O	ko:K07391	-	ko00000	Magnesium chelatase, subunit ChlI C-terminal
HCLPGIIE_00432	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycosyl hydrolase family 20, domain 2
HCLPGIIE_00433	3.56e-179	-	-	-	M	-	-	-	NLP P60 protein
HCLPGIIE_00434	6.77e-87	-	-	-	S	ko:K09940	-	ko00000	Domain of unknown function (DUF4870)
HCLPGIIE_00436	2.09e-76	-	-	-	C	ko:K04651	-	ko00000,ko03110	Hydrogenase/urease nickel incorporation, metallochaperone, hypA
HCLPGIIE_00437	3.4e-126	-	-	-	C	ko:K03605	-	ko00000,ko01000,ko01002	Hydrogenase maturation protease
HCLPGIIE_00438	4.57e-290	hyaC	-	-	C	ko:K03620	ko02020,map02020	ko00000,ko00001	Prokaryotic cytochrome b561
HCLPGIIE_00439	0.0	-	1.12.99.6	-	C	ko:K06281	ko00633,ko01120,map00633,map01120	ko00000,ko00001,ko01000	Nickel-dependent hydrogenase
HCLPGIIE_00440	2.95e-299	-	1.12.99.6	-	C	ko:K06282	ko00633,ko01120,map00633,map01120	ko00000,ko00001,ko01000	NiFe/NiFeSe hydrogenase small subunit C-terminal
HCLPGIIE_00441	0.0	-	-	-	M	ko:K07267	-	ko00000,ko02000	wide pore channel activity
HCLPGIIE_00442	2.95e-190	-	-	-	-	-	-	-	-
HCLPGIIE_00443	5.98e-125	-	-	-	L	-	-	-	Conserved hypothetical protein 95
HCLPGIIE_00444	2.77e-308	-	2.4.99.12, 2.4.99.13, 2.4.99.14, 2.4.99.15	GT30	M	ko:K02527	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase)
HCLPGIIE_00445	2.48e-228	-	-	-	S	-	-	-	Aspartyl protease
HCLPGIIE_00446	1.5e-267	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HCLPGIIE_00447	6.6e-158	-	6.3.2.5	-	H	ko:K21977	ko00770,map00770	ko00000,ko00001,ko00002,ko01000	DNA / pantothenate metabolism flavoprotein
HCLPGIIE_00448	1.93e-270	-	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class-V
HCLPGIIE_00450	9.31e-23	-	-	-	K	ko:K03826	-	ko00000,ko01000	acetyltransferase
HCLPGIIE_00451	2.25e-20	-	-	-	K	ko:K03826	-	ko00000,ko01000	acetyltransferase
HCLPGIIE_00452	2.48e-173	-	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
HCLPGIIE_00453	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
HCLPGIIE_00454	9.77e-278	-	4.2.1.51, 5.4.99.5	-	E	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Chorismate mutase type II
HCLPGIIE_00455	3.72e-237	-	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HCLPGIIE_00456	3.17e-190	-	-	-	S	-	-	-	NIF3 (NGG1p interacting factor 3)
HCLPGIIE_00457	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4340)
HCLPGIIE_00458	2.83e-63	-	-	-	N	-	-	-	ABC-type uncharacterized transport system
HCLPGIIE_00459	3.96e-272	-	-	-	N	-	-	-	ABC-type uncharacterized transport system
HCLPGIIE_00460	1.44e-171	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HCLPGIIE_00461	1.81e-222	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HCLPGIIE_00462	7.06e-286	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HCLPGIIE_00463	3e-148	phoU	-	-	P	ko:K02039	-	ko00000	negative regulation of phosphate transmembrane transport
HCLPGIIE_00464	4.85e-185	-	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HCLPGIIE_00465	0.0	-	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HCLPGIIE_00466	0.0	pstC	-	-	P	ko:K02037,ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HCLPGIIE_00467	2e-218	-	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	PBP superfamily domain
HCLPGIIE_00468	1.18e-181	-	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HCLPGIIE_00469	1.17e-136	-	-	-	P	ko:K02039	-	ko00000	PhoU domain
HCLPGIIE_00470	3.41e-231	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Converts alpha-aldose to the beta-anomer
HCLPGIIE_00471	7.65e-101	-	-	-	M	ko:K06077	-	ko00000	Glycine zipper 2TM domain
HCLPGIIE_00476	1.83e-173	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HCLPGIIE_00477	4.21e-138	mntP	-	-	P	-	-	-	manganese ion transmembrane transporter activity
HCLPGIIE_00478	1.01e-282	-	-	-	-	-	-	-	-
HCLPGIIE_00479	5.78e-237	-	-	-	-	-	-	-	-
HCLPGIIE_00480	7.99e-294	-	-	-	-	-	-	-	-
HCLPGIIE_00481	0.0	-	-	-	L	ko:K07478	-	ko00000	MgsA AAA+ ATPase C terminal
HCLPGIIE_00483	1.01e-222	-	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	NmrA-like family
HCLPGIIE_00484	2.88e-273	-	-	-	S	-	-	-	Phosphotransferase enzyme family
HCLPGIIE_00485	2.27e-215	-	-	-	JM	-	-	-	Nucleotidyl transferase
HCLPGIIE_00487	1.15e-44	-	-	-	K	-	-	-	-acetyltransferase
HCLPGIIE_00488	1.15e-146	-	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HCLPGIIE_00489	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HCLPGIIE_00491	4.89e-237	-	4.2.1.24	-	H	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko04147	Delta-aminolevulinic acid dehydratase
HCLPGIIE_00493	1.18e-159	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
HCLPGIIE_00494	0.0	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
HCLPGIIE_00495	8.15e-229	-	4.1.1.35	-	M	ko:K08678	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko00002,ko01000	3-beta hydroxysteroid dehydrogenase/isomerase family
HCLPGIIE_00496	2.93e-181	-	-	-	I	-	-	-	Acyl-ACP thioesterase
HCLPGIIE_00498	1.71e-243	-	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Galactokinase galactose-binding signature
HCLPGIIE_00499	0.0	-	-	-	S	ko:K03307	-	ko00000	Sodium:solute symporter family
HCLPGIIE_00501	0.0	-	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	UvrD-like helicase C-terminal domain
HCLPGIIE_00502	2.62e-225	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HCLPGIIE_00503	8.16e-265	-	-	-	M	-	-	-	Monogalactosyldiacylglycerol (MGDG) synthase
HCLPGIIE_00504	5.89e-173	coaX	2.7.1.33	-	K	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Type III pantothenate kinase
HCLPGIIE_00505	8.56e-45	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Phosphopantetheine attachment site
HCLPGIIE_00506	7.48e-127	-	-	-	-	-	-	-	-
HCLPGIIE_00507	1.67e-174	-	-	-	S	-	-	-	Lysin motif
HCLPGIIE_00508	5.95e-96	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HCLPGIIE_00512	1.56e-259	-	2.3.1.47	-	H	ko:K00652	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
HCLPGIIE_00513	7.26e-285	-	-	-	IQ	-	-	-	Beta-ketoacyl synthase, C-terminal domain
HCLPGIIE_00514	0.0	-	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	thiolester hydrolase activity
HCLPGIIE_00515	3.08e-286	-	-	-	S	-	-	-	Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units
HCLPGIIE_00516	9.4e-148	-	-	-	IQ	-	-	-	RmlD substrate binding domain
HCLPGIIE_00517	0.0	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	GcpE protein
HCLPGIIE_00518	0.0	-	-	-	M	-	-	-	Bacterial membrane protein, YfhO
HCLPGIIE_00519	2.73e-271	-	-	-	S	-	-	-	COG0790 FOG TPR repeat, SEL1 subfamily
HCLPGIIE_00520	4.89e-239	-	-	-	O	ko:K04655	-	ko00000	AIR synthase related protein, N-terminal domain
HCLPGIIE_00521	1.14e-254	-	-	-	O	ko:K04654	-	ko00000	Hydrogenase formation hypA family
HCLPGIIE_00522	9.56e-51	-	-	-	O	ko:K04653	-	ko00000	HupF/HypC family
HCLPGIIE_00523	0.0	-	-	-	O	ko:K04656	-	ko00000	HypF finger
HCLPGIIE_00524	1.02e-175	hypB	-	-	KO	ko:K04652	-	ko00000,ko03110	CobW/HypB/UreG, nucleotide-binding domain
HCLPGIIE_00525	7.37e-311	-	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Histidyl-tRNA synthetase
HCLPGIIE_00526	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HCLPGIIE_00528	3.7e-40	-	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Ribosomal protein S6
HCLPGIIE_00529	1.53e-146	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HCLPGIIE_00530	1.48e-141	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Imidazoleglycerol-phosphate dehydratase
HCLPGIIE_00532	1.51e-132	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HCLPGIIE_00533	4.58e-220	prs	2.7.6.1	-	EF	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HCLPGIIE_00534	8.36e-230	-	-	-	C	-	-	-	Transmembrane exosortase (Exosortase_EpsH)
HCLPGIIE_00535	2.92e-172	-	-	-	S	-	-	-	Protein of unknown function (DUF3485)
HCLPGIIE_00536	5.71e-165	pks6	-	-	Q	-	-	-	amino acid activation for nonribosomal peptide biosynthetic process
HCLPGIIE_00537	6.29e-151	-	-	-	-	-	-	-	-
HCLPGIIE_00538	0.0	-	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
HCLPGIIE_00542	3.08e-134	-	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	Peptidyl-tRNA hydrolase
HCLPGIIE_00543	1.53e-213	-	-	-	S	-	-	-	Protein of unknown function DUF58
HCLPGIIE_00544	4.46e-230	-	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
HCLPGIIE_00545	7.05e-216	-	3.5.1.53	-	K	ko:K12251	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
HCLPGIIE_00547	5.79e-274	-	-	-	E	-	-	-	Alcohol dehydrogenase GroES-like domain
HCLPGIIE_00548	1.43e-309	-	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Seryl-tRNA synthetase N-terminal domain
HCLPGIIE_00550	1.04e-18	-	-	-	H	-	-	-	Elongator protein 3, MiaB family, Radical SAM
HCLPGIIE_00553	4.71e-06	-	-	-	L	-	-	-	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HCLPGIIE_00554	1e-20	-	-	-	-	-	-	-	-
HCLPGIIE_00558	1.61e-137	-	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	DnaB-like helicase C terminal domain
HCLPGIIE_00560	4.43e-73	-	-	-	Q	-	-	-	DNA (cytosine-5-)-methyltransferase activity
HCLPGIIE_00563	2.08e-264	-	-	-	H	-	-	-	Elongator protein 3, MiaB family, Radical SAM
HCLPGIIE_00564	0.0	yidC	-	-	O	ko:K03217,ko:K06872	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	serine-type endopeptidase activity
HCLPGIIE_00565	3.72e-158	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
HCLPGIIE_00566	3.77e-127	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HCLPGIIE_00567	6.58e-253	-	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Glycosyl hydrolase family 3 N terminal domain
HCLPGIIE_00568	8.66e-224	exsH	3.2.1.178, 3.2.1.18, 3.2.1.52	GH16,GH20,GH33	G	ko:K01186,ko:K12373,ko:K20830	ko00511,ko00513,ko00520,ko00531,ko00600,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00600,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko02042,ko03110	xyloglucan:xyloglucosyl transferase activity
HCLPGIIE_00569	0.0	-	-	-	I	ko:K06889,ko:K09914	-	ko00000	PFAM Prenyltransferase squalene oxidase
HCLPGIIE_00570	2.92e-198	-	-	-	S	-	-	-	Tetratricopeptide repeat
HCLPGIIE_00571	1.15e-184	-	-	-	T	-	-	-	Calcineurin-like phosphoesterase superfamily domain
HCLPGIIE_00572	0.0	-	-	-	EP	ko:K13894	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HCLPGIIE_00573	0.0	-	-	-	P	ko:K13895	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HCLPGIIE_00574	0.0	-	-	-	E	ko:K13893	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HCLPGIIE_00575	7.73e-231	-	-	-	EP	ko:K02031	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
HCLPGIIE_00576	8.83e-242	-	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
HCLPGIIE_00577	6.31e-253	-	5.1.1.1	-	M	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HCLPGIIE_00579	0.0	-	1.2.1.88, 1.5.5.2	-	CE	ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko03000	Proline dehydrogenase
HCLPGIIE_00580	7.62e-284	-	-	-	S	-	-	-	Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units
HCLPGIIE_00581	6.06e-118	-	-	-	L	ko:K19118	-	ko00000,ko02048	CRISPR-associated protein Cas7
HCLPGIIE_00582	6.84e-159	-	-	-	S	ko:K19117	-	ko00000,ko02048	TIGRFAM CRISPR-associated protein
HCLPGIIE_00585	4.49e-62	tagD	2.7.7.39	-	H	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Glycerol-3-phosphate cytidylyltransferase
HCLPGIIE_00586	4.89e-45	-	-	-	M	ko:K07271	-	ko00000,ko01000	LicD family
HCLPGIIE_00587	9.38e-125	-	-	-	S	-	-	-	protein trimerization
HCLPGIIE_00589	9.69e-170	-	2.1.1.144, 2.1.1.197	-	FG	ko:K00598,ko:K02169	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	trans-aconitate 2-methyltransferase activity
HCLPGIIE_00590	0.0	-	2.7.7.9	-	G	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP--glucose-1-phosphate uridylyltransferase
HCLPGIIE_00591	4.06e-115	-	-	-	-	-	-	-	-
HCLPGIIE_00592	1.31e-62	-	-	-	J	-	-	-	RF-1 domain
HCLPGIIE_00593	1.47e-121	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HCLPGIIE_00594	6.52e-270	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
HCLPGIIE_00596	5.56e-84	-	-	-	K	-	-	-	Lrp/AsnC ligand binding domain
HCLPGIIE_00597	1.12e-286	-	-	-	E	ko:K10907	-	ko00000,ko01000,ko01007	Cys/Met metabolism PLP-dependent enzyme
HCLPGIIE_00598	7.88e-209	-	-	-	S	-	-	-	CAAX protease self-immunity
HCLPGIIE_00599	7.79e-155	-	-	-	S	-	-	-	DUF218 domain
HCLPGIIE_00600	0.0	-	6.1.1.14	-	J	ko:K01880	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Anticodon binding domain
HCLPGIIE_00601	1.16e-205	yeaE	-	-	S	-	-	-	aldo-keto reductase (NADP) activity
HCLPGIIE_00602	0.0	-	-	-	S	-	-	-	Oxygen tolerance
HCLPGIIE_00603	8.51e-42	-	-	-	S	ko:K07114	-	ko00000,ko02000	von Willebrand factor (vWF) type A domain
HCLPGIIE_00604	4.53e-206	-	-	-	S	-	-	-	Rhomboid family
HCLPGIIE_00605	6.19e-268	-	-	-	E	-	-	-	FAD dependent oxidoreductase
HCLPGIIE_00606	2.64e-267	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HCLPGIIE_00609	0.0	-	-	-	S	-	-	-	Phosphoadenosine phosphosulfate reductase
HCLPGIIE_00610	3.45e-121	-	-	-	K	-	-	-	ParB domain protein nuclease
HCLPGIIE_00613	9.17e-116	-	-	-	L	-	-	-	Staphylococcal nuclease homologues
HCLPGIIE_00614	3.64e-243	-	-	-	M	-	-	-	Alginate lyase
HCLPGIIE_00615	8.47e-205	-	-	-	IQ	-	-	-	KR domain
HCLPGIIE_00617	2.08e-75	-	-	-	S	ko:K07126	-	ko00000	beta-lactamase activity
HCLPGIIE_00618	0.0	-	-	-	S	ko:K07126	-	ko00000	beta-lactamase activity
HCLPGIIE_00619	0.0	-	-	-	L	-	-	-	TRCF
HCLPGIIE_00620	5.4e-295	-	-	-	-	-	-	-	-
HCLPGIIE_00621	0.0	-	-	-	G	-	-	-	Major Facilitator Superfamily
HCLPGIIE_00622	1.77e-100	-	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Pyruvate kinase, barrel domain
HCLPGIIE_00623	5.73e-120	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HCLPGIIE_00627	1.37e-164	-	-	-	E	-	-	-	haloacid dehalogenase-like hydrolase
HCLPGIIE_00628	7.24e-141	-	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S4/S9 N-terminal domain
HCLPGIIE_00629	3.5e-120	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HCLPGIIE_00630	1.11e-79	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HCLPGIIE_00631	8.81e-267	-	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Domain of unknown function (DUF1730)
HCLPGIIE_00632	3.12e-220	-	-	-	M	ko:K07276	-	ko00000	Mitochondrial fission ELM1
HCLPGIIE_00635	0.0	-	2.8.4.4	-	J	ko:K14441	-	ko00000,ko01000,ko03009	Uncharacterized protein family UPF0004
HCLPGIIE_00636	0.0	-	-	-	-	ko:K07403	-	ko00000	-
HCLPGIIE_00637	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HCLPGIIE_00638	0.0	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HCLPGIIE_00639	2.82e-182	-	3.4.13.22	-	M	ko:K08641	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-ala-D-ala dipeptidase
HCLPGIIE_00643	5.39e-130	-	-	-	S	-	-	-	Glycosyl hydrolase 108
HCLPGIIE_00645	1.38e-114	-	-	-	S	-	-	-	Bacteriophage head to tail connecting protein
HCLPGIIE_00650	2.11e-173	-	6.3.5.11, 6.3.5.9	-	V	ko:K02224,ko:K18554	ko00860,ko01100,ko01120,map00860,map01100,map01120	br01600,ko00000,ko00001,ko01000,ko01504	Chloramphenicol phosphotransferase-like protein
HCLPGIIE_00651	2.63e-82	-	-	-	K	ko:K07343	-	ko00000	positive regulation of type IV pilus biogenesis
HCLPGIIE_00652	1.66e-225	-	-	-	CO	-	-	-	Redoxin
HCLPGIIE_00653	1.73e-123	paiA	-	-	K	-	-	-	acetyltransferase
HCLPGIIE_00654	0.0	-	-	-	-	-	-	-	-
HCLPGIIE_00656	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	PFAM Glycoside hydrolase, family 20, catalytic core
HCLPGIIE_00658	0.0	-	-	-	P	ko:K03281	-	ko00000	Voltage gated chloride channel
HCLPGIIE_00660	9.86e-54	-	-	-	-	-	-	-	-
HCLPGIIE_00661	1.45e-102	-	-	-	-	-	-	-	-
HCLPGIIE_00662	0.0	-	2.1.1.182	-	IJ	ko:K02528	-	ko00000,ko01000,ko03009	Ribosomal RNA adenine dimethylases
HCLPGIIE_00663	1.26e-247	-	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	NmrA-like family
HCLPGIIE_00664	0.0	-	-	-	I	-	-	-	Prenyltransferase and squalene oxidase repeat
HCLPGIIE_00665	0.0	-	-	-	I	-	-	-	Prenyltransferase and squalene oxidase repeat
HCLPGIIE_00666	6.39e-119	-	-	-	T	-	-	-	STAS domain
HCLPGIIE_00668	1.94e-114	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HCLPGIIE_00669	8.75e-95	-	2.3.1.61	-	C	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	2-oxoacid dehydrogenases acyltransferase (catalytic domain)
HCLPGIIE_00670	9.14e-116	-	2.3.1.61	-	C	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	2-oxoacid dehydrogenases acyltransferase (catalytic domain)
HCLPGIIE_00671	0.0	-	1.2.4.2	-	C	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	2-oxoglutarate dehydrogenase C-terminal
HCLPGIIE_00672	1.65e-242	-	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome bd terminal oxidase subunit II
HCLPGIIE_00673	0.0	-	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome bd terminal oxidase subunit I
HCLPGIIE_00674	2.7e-113	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
HCLPGIIE_00675	2.34e-107	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Low molecular weight phosphatase family
HCLPGIIE_00682	0.0	-	-	-	S	ko:K07126	-	ko00000	beta-lactamase activity
HCLPGIIE_00683	3.54e-181	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	AAA domain
HCLPGIIE_00690	8.2e-08	-	-	-	N	-	-	-	HicA toxin of bacterial toxin-antitoxin,
HCLPGIIE_00691	2.61e-18	-	-	-	N	-	-	-	PFAM Uncharacterised protein family UPF0150
HCLPGIIE_00699	3.59e-130	-	2.1.1.37	-	L	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
HCLPGIIE_00702	2.43e-95	-	-	-	K	-	-	-	-acetyltransferase
HCLPGIIE_00703	1.73e-221	-	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Glutaminase
HCLPGIIE_00704	0.0	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	amino acid
HCLPGIIE_00709	5.79e-62	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HCLPGIIE_00711	2.63e-10	-	-	-	-	-	-	-	-
HCLPGIIE_00713	2.51e-280	-	-	-	S	-	-	-	Tetratricopeptide repeat
HCLPGIIE_00714	0.0	-	-	-	S	-	-	-	Sulfatase-modifying factor enzyme 1
HCLPGIIE_00715	5.09e-202	-	-	-	-	-	-	-	-
HCLPGIIE_00716	1.45e-233	-	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
HCLPGIIE_00717	2.21e-52	-	-	-	O	-	-	-	Trypsin
HCLPGIIE_00719	1.33e-52	-	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HCLPGIIE_00720	5.52e-302	-	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
HCLPGIIE_00722	1.82e-312	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HCLPGIIE_00723	7.4e-85	-	-	-	S	ko:K06940	-	ko00000	Putative zinc- or iron-chelating domain
HCLPGIIE_00726	7.99e-189	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Bacitracin resistance protein BacA
HCLPGIIE_00727	2.29e-176	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HCLPGIIE_00729	1.15e-261	-	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Biotin-lipoyl like
HCLPGIIE_00730	1.69e-107	-	-	-	K	-	-	-	DNA-binding transcription factor activity
HCLPGIIE_00732	0.0	-	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
HCLPGIIE_00733	1.6e-128	-	-	-	D	ko:K06287	-	ko00000	Maf-like protein
HCLPGIIE_00734	3.78e-290	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HCLPGIIE_00736	0.0	-	-	-	KLT	-	-	-	Protein tyrosine kinase
HCLPGIIE_00737	0.0	-	-	-	GK	-	-	-	carbohydrate kinase activity
HCLPGIIE_00738	2.51e-201	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HCLPGIIE_00739	6.68e-207	thiL	2.7.4.16	-	H	ko:K00946	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HCLPGIIE_00740	0.0	-	-	-	I	-	-	-	Acetyltransferase (GNAT) domain
HCLPGIIE_00741	6.6e-142	-	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Cytidylate kinase
HCLPGIIE_00742	1.36e-145	-	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
HCLPGIIE_00743	4.31e-257	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HCLPGIIE_00744	6.74e-122	actI	1.5.1.36	-	S	ko:K00484	ko00350,ko00740,ko01100,ko01120,ko01220,map00350,map00740,map01100,map01120,map01220	ko00000,ko00001,ko01000	FMN binding
HCLPGIIE_00745	9.78e-39	-	-	-	V	-	-	-	Abi-like protein
HCLPGIIE_00746	2.2e-158	rnc	3.1.26.3	-	K	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HCLPGIIE_00747	0.0	-	-	-	P	ko:K07221	-	ko00000,ko02000	Phosphate-selective porin O and P
HCLPGIIE_00748	2.72e-18	-	-	-	-	-	-	-	-
HCLPGIIE_00749	5.13e-179	-	-	-	S	-	-	-	Endonuclease/Exonuclease/phosphatase family
HCLPGIIE_00750	4.83e-163	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Tetrapyrrole (Corrin/Porphyrin) Methylases
HCLPGIIE_00751	7.51e-116	-	-	-	S	-	-	-	Lipopolysaccharide-assembly
HCLPGIIE_00752	1.18e-170	-	-	-	S	ko:K05807	-	ko00000,ko02000	Outer membrane lipoprotein
HCLPGIIE_00753	2.03e-116	hisI	3.5.4.19	-	E	ko:K01496	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Phosphoribosyl-AMP cyclohydrolase
HCLPGIIE_00754	3.12e-224	-	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III, delta subunit
HCLPGIIE_00755	1.2e-121	-	3.2.2.28	-	L	ko:K03649	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	G/U mismatch-specific uracil-DNA glycosylase activity
HCLPGIIE_00756	8.78e-197	-	-	-	-	-	-	-	-
HCLPGIIE_00757	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase large chain, oligomerisation domain
HCLPGIIE_00758	1.82e-136	-	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	Serine/threonine phosphatases, family 2C, catalytic domain
HCLPGIIE_00760	6.15e-183	-	-	-	Q	-	-	-	methyltransferase activity
HCLPGIIE_00761	0.0	-	6.3.5.1	-	H	ko:K01950	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	NAD synthase
HCLPGIIE_00762	2.28e-79	-	-	-	P	ko:K11741	-	ko00000,ko02000	Small Multidrug Resistance protein
HCLPGIIE_00763	3.23e-76	-	3.2.1.18	GH33	G	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	ko00000,ko00001,ko01000,ko02042	BNR/Asp-box repeat
HCLPGIIE_00764	6.68e-198	-	2.5.1.55	-	M	ko:K01627	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	DAHP synthetase I family
HCLPGIIE_00765	1.37e-173	cbiX	4.99.1.3	-	S	ko:K03795	ko00860,ko01100,ko01120,map00860,map01100,map01120	ko00000,ko00001,ko01000	sirohydrochlorin cobaltochelatase activity
HCLPGIIE_00766	5.88e-163	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S2
HCLPGIIE_00767	2.05e-198	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HCLPGIIE_00768	2.65e-174	-	-	-	E	-	-	-	ATPases associated with a variety of cellular activities
HCLPGIIE_00770	8.39e-280	-	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	3-dehydroquinate synthase
HCLPGIIE_00771	0.0	-	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
HCLPGIIE_00772	3.9e-139	-	-	-	K	-	-	-	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen
HCLPGIIE_00774	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl tRNA synthetase N terminal dom
HCLPGIIE_00777	0.0	-	3.4.24.70	-	E	ko:K01414	-	ko00000,ko01000,ko01002	Peptidase family M3
HCLPGIIE_00778	0.0	-	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
HCLPGIIE_00779	0.0	rarA	-	-	L	ko:K07478	-	ko00000	MgsA AAA+ ATPase C terminal
HCLPGIIE_00780	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase activity
HCLPGIIE_00781	3.35e-57	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase activity
HCLPGIIE_00782	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Beta galactosidase small chain
HCLPGIIE_00783	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Beta galactosidase small chain
HCLPGIIE_00784	8.04e-185	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
HCLPGIIE_00785	1.54e-255	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HCLPGIIE_00786	0.0	-	4.1.1.19	-	E	ko:K01585	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Pyridoxal-dependent decarboxylase, pyridoxal binding domain
HCLPGIIE_00787	7.45e-301	-	4.1.1.96	-	E	ko:K13747	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	Pyridoxal-dependent decarboxylase, C-terminal sheet domain
HCLPGIIE_00789	0.0	-	-	-	P	-	-	-	Sulfatase
HCLPGIIE_00790	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Leucyl-tRNA synthetase, Domain 2
HCLPGIIE_00791	9.06e-151	-	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribulose-phosphate 3 epimerase family
HCLPGIIE_00792	3.25e-223	-	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Phosphatidylserine decarboxylase
HCLPGIIE_00795	0.0	-	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Thiamine pyrophosphate enzyme, central domain
HCLPGIIE_00796	6.98e-143	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HCLPGIIE_00797	9.53e-43	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S20
HCLPGIIE_00799	1.87e-289	-	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	LytB protein
HCLPGIIE_00800	8.33e-259	-	-	-	J	ko:K05541	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HCLPGIIE_00801	1.9e-281	-	-	-	E	-	-	-	Transglutaminase-like superfamily
HCLPGIIE_00802	6.43e-203	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HCLPGIIE_00803	2.91e-182	-	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
HCLPGIIE_00804	7.21e-203	folD	1.5.1.5, 3.5.4.9	-	H	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HCLPGIIE_00805	7.21e-183	-	-	-	S	ko:K09778	-	ko00000	Domain of unknown function (DUF374)
HCLPGIIE_00806	2.85e-93	-	-	-	-	-	-	-	-
HCLPGIIE_00807	1.88e-111	-	-	-	K	ko:K13640	-	ko00000,ko03000	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
HCLPGIIE_00808	1.54e-96	-	-	-	G	-	-	-	single-species biofilm formation
HCLPGIIE_00809	0.0	-	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
HCLPGIIE_00810	0.0	-	-	-	V	-	-	-	Polysaccharide biosynthesis C-terminal domain
HCLPGIIE_00812	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 20, domain 2
HCLPGIIE_00814	2.58e-52	-	-	-	-	-	-	-	-
HCLPGIIE_00815	2.53e-30	-	-	-	-	-	-	-	-
HCLPGIIE_00816	7.11e-300	-	-	-	V	ko:K03327	-	ko00000,ko02000	drug transmembrane transporter activity
HCLPGIIE_00817	0.0	-	-	-	P	-	-	-	Cation transport protein
HCLPGIIE_00820	9.28e-149	-	-	-	M	ko:K17733	-	ko00000,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
HCLPGIIE_00825	1.37e-176	-	4.1.1.48	-	E	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Indole-3-glycerol phosphate synthase
HCLPGIIE_00827	4.83e-82	-	-	-	L	ko:K07460	-	ko00000	Uncharacterised protein family UPF0102
HCLPGIIE_00828	2.93e-150	-	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HII
HCLPGIIE_00829	2.17e-306	-	-	-	S	-	-	-	PFAM CBS domain containing protein
HCLPGIIE_00830	1.7e-58	-	-	-	S	-	-	-	Zinc ribbon domain
HCLPGIIE_00831	2.79e-54	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HCLPGIIE_00832	1.55e-315	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Arginosuccinate synthase
HCLPGIIE_00833	9.36e-114	-	3.1.6.8	-	P	ko:K01134	ko00600,ko04142,map00600,map04142	ko00000,ko00001,ko01000	COG3119 Arylsulfatase A
HCLPGIIE_00834	4.36e-98	-	-	-	S	-	-	-	peptidase
HCLPGIIE_00835	0.0	-	-	-	P	ko:K03306	-	ko00000	phosphate transporter
HCLPGIIE_00839	1.14e-297	-	-	-	-	-	-	-	-
HCLPGIIE_00840	0.0	-	-	-	D	-	-	-	Chain length determinant protein
HCLPGIIE_00841	1.03e-139	-	-	-	M	-	-	-	Polysaccharide biosynthesis/export protein
HCLPGIIE_00843	5.19e-170	-	-	-	S	ko:K06861	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HCLPGIIE_00844	3.12e-219	-	-	-	E	-	-	-	Phosphoserine phosphatase
HCLPGIIE_00845	0.0	-	6.3.2.45	-	M	ko:K02558	-	ko00000,ko01000	Mur ligase family, catalytic domain
HCLPGIIE_00846	1.48e-304	-	-	-	M	-	-	-	OmpA family
HCLPGIIE_00847	0.0	-	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	UvrD-like helicase C-terminal domain
HCLPGIIE_00848	4.59e-86	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HCLPGIIE_00850	8.49e-288	-	-	-	-	-	-	-	-
HCLPGIIE_00851	0.0	-	-	-	M	-	-	-	Sulfatase
HCLPGIIE_00852	1.4e-287	-	4.1.99.19	-	H	ko:K03150	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Biotin and Thiamin Synthesis associated domain
HCLPGIIE_00853	3.98e-206	-	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil DNA glycosylase superfamily
HCLPGIIE_00854	1.6e-184	-	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidine biosynthesis protein
HCLPGIIE_00855	3.01e-59	-	-	-	S	ko:K09131	-	ko00000	DUF167
HCLPGIIE_00856	1.41e-115	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HCLPGIIE_00857	2.7e-259	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HCLPGIIE_00858	1.2e-235	-	3.1.3.18	-	F	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD-hyrolase-like
HCLPGIIE_00859	0.0	-	-	-	M	-	-	-	Parallel beta-helix repeats
HCLPGIIE_00860	8.34e-228	-	2.5.1.32, 2.5.1.99	-	I	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Squalene/phytoene synthase
HCLPGIIE_00861	1.07e-52	-	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Peptidase S24-like
HCLPGIIE_00863	0.0	-	-	-	I	-	-	-	Acyltransferase family
HCLPGIIE_00864	4.98e-251	-	-	-	S	-	-	-	Glycosyltransferase family 10 (fucosyltransferase) C-term
HCLPGIIE_00865	5.14e-303	-	-	-	M	-	-	-	Glycosyl transferases group 1
HCLPGIIE_00866	1e-46	-	-	-	-	-	-	-	-
HCLPGIIE_00867	1.12e-105	-	-	-	-	-	-	-	-
HCLPGIIE_00868	2.25e-287	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HCLPGIIE_00872	7.29e-211	-	-	-	M	-	-	-	Peptidase family M23
HCLPGIIE_00873	1.76e-78	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
HCLPGIIE_00874	8.95e-110	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
HCLPGIIE_00875	4.13e-183	panB	2.1.2.11	-	H	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
HCLPGIIE_00876	4.21e-121	-	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
HCLPGIIE_00877	4.14e-175	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Dihydrodipicolinate reductase, N-terminus
HCLPGIIE_00878	4.17e-203	dapA	4.3.3.7	-	EM	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Dihydrodipicolinate synthetase family
HCLPGIIE_00882	0.0	-	-	-	G	-	-	-	Glycosyl transferase 4-like domain
HCLPGIIE_00883	8.59e-293	-	3.2.1.1	GH57	G	ko:K07405	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolase family 57
HCLPGIIE_00884	8.02e-130	-	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HCLPGIIE_00885	8.95e-22	-	-	-	U	ko:K03559	-	ko00000,ko02000	Biopolymer transport protein ExbD/TolR
HCLPGIIE_00886	2.91e-53	-	-	-	U	ko:K03559	-	ko00000,ko02000	Biopolymer transport protein ExbD/TolR
HCLPGIIE_00887	2.29e-136	-	-	-	U	ko:K03561	-	ko00000,ko02000	MotA/TolQ/ExbB proton channel family
HCLPGIIE_00888	3.2e-284	-	5.4.99.22	-	M	ko:K06178	-	ko00000,ko01000,ko03009	translation initiation factor activity
HCLPGIIE_00890	2.23e-272	ycaD	-	-	EGP	ko:K08219	-	ko00000,ko02000	Major facilitator Superfamily
HCLPGIIE_00891	1.43e-223	-	3.4.11.10, 3.4.11.6	-	DZ	ko:K19701	-	ko00000,ko01000,ko01002	aminopeptidase activity
HCLPGIIE_00892	4.04e-288	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
HCLPGIIE_00893	0.0	-	-	-	S	-	-	-	inositol 2-dehydrogenase activity
HCLPGIIE_00896	2.09e-270	-	3.6.4.13	-	L	ko:K11927	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	helicase superfamily c-terminal domain
HCLPGIIE_00899	3.83e-240	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HCLPGIIE_00900	4.46e-238	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HCLPGIIE_00901	0.0	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HCLPGIIE_00902	6.51e-226	-	-	-	M	ko:K01993	-	ko00000	HlyD family secretion protein
HCLPGIIE_00904	6.05e-254	-	-	-	S	-	-	-	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
HCLPGIIE_00906	5.56e-214	-	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	PHP domain
HCLPGIIE_00907	5.69e-259	-	2.3.1.8	-	C	ko:K00625	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Phosphate acetyl/butaryl transferase
HCLPGIIE_00908	1.65e-241	tilS	6.3.4.19	-	D	ko:K04075	-	ko00000,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HCLPGIIE_00909	2.59e-75	-	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
HCLPGIIE_00913	0.0	-	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	transmembrane transport
HCLPGIIE_00914	2.76e-270	-	-	-	S	-	-	-	tRNA-splicing ligase RtcB
HCLPGIIE_00915	2.16e-211	-	-	-	K	-	-	-	LysR substrate binding domain
HCLPGIIE_00916	4.12e-294	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HCLPGIIE_00918	7.1e-130	-	-	-	S	-	-	-	Cobalamin adenosyltransferase
HCLPGIIE_00919	2.1e-71	-	-	-	L	-	-	-	Cupin 2, conserved barrel domain protein
HCLPGIIE_00921	0.0	-	-	-	-	-	-	-	-
HCLPGIIE_00922	1.43e-172	kdsB	2.7.7.38	-	M	ko:K00979	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
HCLPGIIE_00923	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HCLPGIIE_00924	0.0	-	-	-	E	-	-	-	Sodium:solute symporter family
HCLPGIIE_00925	0.0	-	-	-	-	-	-	-	-
HCLPGIIE_00927	5.1e-265	-	-	-	NU	ko:K02669	-	ko00000,ko02035,ko02044	Type II/IV secretion system protein
HCLPGIIE_00930	2.69e-38	-	-	-	T	-	-	-	ribosome binding
HCLPGIIE_00931	7.39e-229	-	-	-	Q	ko:K02067	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	MlaD protein
HCLPGIIE_00932	6.12e-190	-	-	-	Q	ko:K02065	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
HCLPGIIE_00933	7.86e-174	-	-	-	Q	ko:K02066	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Permease MlaE
HCLPGIIE_00934	0.0	-	-	-	H	-	-	-	NAD synthase
HCLPGIIE_00935	0.0	-	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter transmembrane region
HCLPGIIE_00936	0.0	-	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter transmembrane region
HCLPGIIE_00937	0.0	-	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III
HCLPGIIE_00938	3.9e-144	-	-	-	M	-	-	-	NLP P60 protein
HCLPGIIE_00939	4.42e-290	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HCLPGIIE_00940	3.8e-300	-	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Tubulin/FtsZ family, GTPase domain
HCLPGIIE_00944	1.54e-229	-	-	-	S	ko:K01128	-	ko00000,ko01000	acid phosphatase activity
HCLPGIIE_00945	1.53e-309	-	1.5.1.7	-	E	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Saccharopine dehydrogenase C-terminal domain
HCLPGIIE_00946	1.31e-209	-	-	-	O	-	-	-	Thioredoxin-like domain
HCLPGIIE_00947	0.0	-	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HCLPGIIE_00948	5.13e-214	-	-	-	EP	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HCLPGIIE_00949	5.13e-210	-	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	N-terminal TM domain of oligopeptide transport permease C
HCLPGIIE_00950	3.38e-83	-	-	-	S	ko:K09922	-	ko00000	Putative member of DMT superfamily (DUF486)
HCLPGIIE_00952	1.78e-270	-	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	tRNA synthetases class I (W and Y)
HCLPGIIE_00953	2.61e-234	-	-	-	S	ko:K14347	-	ko00000,ko02000,ko04147	SBF-like CPA transporter family (DUF4137)
HCLPGIIE_00956	0.0	-	-	-	S	-	-	-	Large extracellular alpha-helical protein
HCLPGIIE_00963	1.55e-169	truB	5.4.99.25	-	J	ko:K03177	-	ko00000,ko01000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HCLPGIIE_00964	8.48e-241	-	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain
HCLPGIIE_00966	2.54e-208	lpxG	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase
HCLPGIIE_00967	4.53e-244	-	-	-	H	-	-	-	PFAM glycosyl transferase family 8
HCLPGIIE_00968	3.87e-239	-	-	-	S	-	-	-	Glycosyltransferase like family 2
HCLPGIIE_00969	2.6e-233	-	-	GT9	M	ko:K02843,ko:K02849	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	ADP-heptose-lipopolysaccharide heptosyltransferase activity
HCLPGIIE_00970	1.31e-244	-	5.1.3.20	-	M	ko:K03274	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	3-beta hydroxysteroid dehydrogenase/isomerase family
HCLPGIIE_00972	7.39e-225	-	-	-	S	-	-	-	Polyphosphate kinase 2 (PPK2)
HCLPGIIE_00973	0.0	-	-	-	-	-	-	-	-
HCLPGIIE_00974	0.0	-	-	-	M	-	-	-	Parallel beta-helix repeats
HCLPGIIE_00976	2.16e-199	-	-	-	S	ko:K06889	-	ko00000	alpha beta
HCLPGIIE_00977	5.76e-107	-	-	-	S	ko:K06925	-	ko00000,ko03016	Threonylcarbamoyl adenosine biosynthesis protein TsaE
HCLPGIIE_00978	9.17e-243	-	-	-	H	-	-	-	PFAM glycosyl transferase family 8
HCLPGIIE_00979	1.68e-246	-	-	-	M	-	-	-	Glycosyl transferase, family 2
HCLPGIIE_00980	5.22e-255	MA20_42350	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	Glycosyl transferase, family 2
HCLPGIIE_00981	1.29e-282	-	1.8.1.2	-	P	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HCLPGIIE_00982	1.57e-237	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HCLPGIIE_00983	7.91e-214	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HCLPGIIE_00984	0.0	-	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase large chain, oligomerisation domain
HCLPGIIE_00985	1.8e-271	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase small chain, CPSase domain
HCLPGIIE_00986	6.96e-265	-	4.2.1.47	-	M	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
HCLPGIIE_00987	1.31e-268	fcl	1.1.1.271	-	GM	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction
HCLPGIIE_00988	1.45e-296	-	-	-	C	-	-	-	Na+/H+ antiporter family
HCLPGIIE_00989	1.01e-276	-	-	-	-	-	-	-	-
HCLPGIIE_00990	1.62e-227	-	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphomannose isomerase type I
HCLPGIIE_00991	3.71e-181	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	PFAM N-acetylmuramoyl-L-alanine amidase family 2
HCLPGIIE_00992	7.54e-115	ispF	4.6.1.12	-	I	ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HCLPGIIE_00993	5.6e-180	-	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase family
HCLPGIIE_00994	0.0	-	-	-	M	-	-	-	PFAM glycosyl transferase family 51
HCLPGIIE_00995	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
HCLPGIIE_00996	6.23e-97	-	-	-	U	ko:K03559	-	ko00000,ko02000	Biopolymer transport protein ExbD/TolR
HCLPGIIE_00997	2.47e-180	-	-	-	U	ko:K03561	-	ko00000,ko02000	MotA/TolQ/ExbB proton channel family
HCLPGIIE_00998	0.0	-	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HCLPGIIE_00999	1.04e-98	-	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Predicted SPOUT methyltransferase
HCLPGIIE_01000	4.8e-86	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S9/S16
HCLPGIIE_01001	2.79e-97	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HCLPGIIE_01002	6.12e-40	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HCLPGIIE_01003	0.0	nnrD	4.2.1.136, 5.1.99.6	-	G	ko:K17758,ko:K17759	-	ko00000,ko01000	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HCLPGIIE_01004	1.62e-172	-	-	-	L	ko:K03630	-	ko00000	RadC-like JAB domain
HCLPGIIE_01006	4.03e-174	-	-	-	D	-	-	-	Phage-related minor tail protein
HCLPGIIE_01008	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HCLPGIIE_01009	9.28e-60	-	-	-	L	ko:K09747	-	ko00000	YbaB/EbfC DNA-binding family
HCLPGIIE_01010	1.63e-230	-	-	-	N	ko:K18353	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01504	Endonuclease Exonuclease Phosphatase
HCLPGIIE_01011	0.0	-	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	DHHA2
HCLPGIIE_01013	1.57e-188	-	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Orotidine 5'-phosphate decarboxylase / HUMPS family
HCLPGIIE_01014	0.0	-	-	-	S	-	-	-	OPT oligopeptide transporter protein
HCLPGIIE_01015	3.41e-271	nuoD	1.6.5.3	-	C	ko:K00333	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HCLPGIIE_01016	2.88e-142	-	1.6.5.3	-	C	ko:K00334	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Thioredoxin-like [2Fe-2S] ferredoxin
HCLPGIIE_01017	0.0	-	1.6.5.3	-	C	ko:K00335	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region
HCLPGIIE_01018	0.0	-	1.6.5.3	-	C	ko:K00336	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region
HCLPGIIE_01019	1.04e-309	nuoH	1.6.5.3	-	C	ko:K00337	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
HCLPGIIE_01020	1.8e-124	nuoI	1.6.5.3	-	C	ko:K00338	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HCLPGIIE_01022	3.58e-199	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HCLPGIIE_01025	5.91e-159	menG	2.1.1.163, 2.1.1.201	-	Q	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	ubiE/COQ5 methyltransferase family
HCLPGIIE_01026	0.0	-	-	-	V	-	-	-	MatE
HCLPGIIE_01028	0.0	-	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	DHHA1 domain
HCLPGIIE_01030	1.08e-136	rbr	-	-	C	-	-	-	Rubrerythrin
HCLPGIIE_01031	1.79e-143	-	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HCLPGIIE_01033	0.0	-	-	-	D	ko:K03466	-	ko00000,ko03036	Ftsk_gamma
HCLPGIIE_01034	9.08e-166	-	-	-	-	-	-	-	-
HCLPGIIE_01035	1.15e-233	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HCLPGIIE_01036	1.62e-200	-	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Polyprenyl synthetase
HCLPGIIE_01037	6.5e-188	-	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Quinolinate phosphoribosyl transferase, N-terminal domain
HCLPGIIE_01038	4.71e-155	-	1.4.3.5	-	H	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)
HCLPGIIE_01039	7.48e-159	-	5.1.3.15	-	G	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Aldose 1-epimerase
HCLPGIIE_01040	0.0	-	-	-	G	-	-	-	Trehalase
HCLPGIIE_01042	7.7e-285	-	3.5.1.42	-	S	ko:K03742	ko00760,map00760	ko00000,ko00001,ko01000	Competence-damaged protein
HCLPGIIE_01043	6.46e-150	-	-	-	O	-	-	-	methyltransferase activity
HCLPGIIE_01044	3.01e-187	-	-	-	U	ko:K20276	ko02024,map02024	ko00000,ko00001	domain, Protein
HCLPGIIE_01045	0.0	-	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	DnaB-like helicase C terminal domain
HCLPGIIE_01046	9.8e-258	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Elongator protein 3, MiaB family, Radical SAM
HCLPGIIE_01047	5.11e-14	-	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	SRP54-type protein, GTPase domain
HCLPGIIE_01048	1e-232	-	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
HCLPGIIE_01049	3.22e-124	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
HCLPGIIE_01051	5.35e-289	kbl	2.3.1.29	-	E	ko:K00639	ko00260,map00260	ko00000,ko00001,ko01000,ko01007	Aminotransferase class I and II
HCLPGIIE_01052	0.0	-	-	-	KLT	-	-	-	Sulfatase-modifying factor enzyme 1
HCLPGIIE_01053	5.22e-265	-	-	-	P	ko:K03449	-	ko00000,ko02000	Major Facilitator Superfamily
HCLPGIIE_01054	0.0	-	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	transmembrane transport
HCLPGIIE_01055	0.0	htpG	-	-	O	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	Hsp90 protein
HCLPGIIE_01056	6.67e-172	-	-	-	P	ko:K10716	-	ko00000,ko02000	domain protein
HCLPGIIE_01058	1.92e-69	-	-	-	V	-	-	-	Domain of unknown function (DUF3387)
HCLPGIIE_01060	0.0	-	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
HCLPGIIE_01061	7.21e-281	-	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
HCLPGIIE_01062	1.12e-116	agmK	1.8.1.8	-	O	ko:K03671,ko:K03672	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko01000,ko03110	belongs to the thioredoxin family
HCLPGIIE_01063	2.72e-181	-	-	-	S	-	-	-	Integral membrane protein (intg_mem_TP0381)
HCLPGIIE_01066	7.87e-236	-	-	-	S	-	-	-	PFAM Sel1 domain protein repeat-containing protein
HCLPGIIE_01067	8.48e-56	tatA	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HCLPGIIE_01068	0.0	-	-	-	J	ko:K07576	-	ko00000	Beta-Casp domain
HCLPGIIE_01069	1.49e-81	-	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	ArsC family
HCLPGIIE_01070	2.05e-180	-	-	-	P	ko:K10716	-	ko00000,ko02000	domain protein
HCLPGIIE_01071	0.0	-	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Carbohydrate phosphorylase
HCLPGIIE_01072	2.04e-258	tdh	1.1.1.103	-	E	ko:K00060	ko00260,map00260	ko00000,ko00001,ko01000	Alcohol dehydrogenase GroES-like domain
HCLPGIIE_01073	2.22e-160	-	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HCLPGIIE_01075	1.33e-183	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HCLPGIIE_01076	3.92e-115	-	-	-	-	-	-	-	-
HCLPGIIE_01080	0.0	-	-	-	L	-	-	-	DNA restriction-modification system
HCLPGIIE_01083	2.64e-159	-	-	-	S	-	-	-	PFAM Sel1 domain protein repeat-containing protein
HCLPGIIE_01085	1.38e-173	-	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HCLPGIIE_01087	2.27e-305	-	-	-	P	ko:K14445	-	ko00000,ko02000	Citrate transporter
HCLPGIIE_01088	0.0	-	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HCLPGIIE_01089	2.95e-262	mtrC	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HCLPGIIE_01090	0.0	-	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
HCLPGIIE_01092	0.0	-	-	-	G	-	-	-	alpha-galactosidase
HCLPGIIE_01093	8.11e-202	-	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase (PrmA)
HCLPGIIE_01094	9.97e-141	-	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Lumazine binding domain
HCLPGIIE_01095	0.0	-	-	-	P	-	-	-	Putative Na+/H+ antiporter
HCLPGIIE_01096	0.0	-	-	-	G	-	-	-	Polysaccharide deacetylase
HCLPGIIE_01103	5.46e-22	-	-	-	OU	-	-	-	Serine dehydrogenase proteinase
HCLPGIIE_01107	3.13e-184	-	-	GT4	M	ko:K16703	-	ko00000,ko01000,ko01003	transferase activity, transferring glycosyl groups
HCLPGIIE_01108	6.07e-252	-	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HCLPGIIE_01109	3.17e-176	-	-	-	S	-	-	-	Phosphotransferase enzyme family
HCLPGIIE_01110	2.42e-71	-	-	-	S	-	-	-	Phosphotransferase enzyme family
HCLPGIIE_01111	2.66e-252	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HCLPGIIE_01113	1.78e-134	-	-	-	T	-	-	-	histone H2A K63-linked ubiquitination
HCLPGIIE_01114	1.39e-130	-	2.1.1.63	-	L	ko:K00567	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HCLPGIIE_01115	5.11e-222	-	-	-	G	-	-	-	Glycosyl hydrolases family 16
HCLPGIIE_01116	8.55e-214	-	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HCLPGIIE_01117	0.0	-	-	-	T	ko:K06207	-	ko00000	Elongation factor G C-terminus
HCLPGIIE_01118	1.32e-235	-	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
HCLPGIIE_01119	2.39e-314	-	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-dependent decarboxylase, pyridoxal binding domain
HCLPGIIE_01120	6.62e-257	-	-	-	S	ko:K11744	-	ko00000	AI-2E family transporter
HCLPGIIE_01121	3.42e-157	gph	3.1.3.18, 3.6.1.1	-	S	ko:K01091,ko:K06019	ko00190,ko00630,ko01100,ko01110,ko01130,map00190,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	glycolate biosynthetic process
HCLPGIIE_01122	9.24e-293	-	-	-	E	-	-	-	Amino acid permease
HCLPGIIE_01123	7.04e-174	-	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Thiazole biosynthesis protein ThiG
HCLPGIIE_01125	1.03e-200	-	-	-	S	-	-	-	SigmaW regulon antibacterial
HCLPGIIE_01126	1.36e-242	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HCLPGIIE_01128	0.0	-	-	-	P	ko:K03455	-	ko00000	TrkA-N domain
HCLPGIIE_01129	0.0	-	-	-	P	-	-	-	Dimerisation domain of Zinc Transporter
HCLPGIIE_01130	5.84e-173	-	-	-	K	-	-	-	Transcriptional regulator
HCLPGIIE_01131	0.0	-	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HCLPGIIE_01132	2.32e-167	-	4.3.99.3	-	O	ko:K10026	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HCLPGIIE_01133	6.56e-196	-	2.7.13.3	-	Q	ko:K07777	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Transposase
HCLPGIIE_01134	0.0	-	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
HCLPGIIE_01135	6.62e-163	-	-	-	S	-	-	-	Protein of unknown function (DUF1015)
HCLPGIIE_01136	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	PFAM Glycoside hydrolase, family 20, catalytic core
HCLPGIIE_01138	1.02e-296	-	2.7.1.11, 2.7.1.90	-	H	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions
HCLPGIIE_01139	6.37e-190	-	-	-	M	-	-	-	Carbohydrate esterase, sialic acid-specific acetylesterase
HCLPGIIE_01140	8.87e-269	-	-	-	K	-	-	-	Periplasmic binding protein-like domain
HCLPGIIE_01141	0.0	-	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Anthranilate synthase component I, N terminal region
HCLPGIIE_01142	0.0	trpD	2.4.2.18, 4.1.3.27	-	E	ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HCLPGIIE_01143	1.37e-176	-	4.1.1.48	-	E	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Indole-3-glycerol phosphate synthase
HCLPGIIE_01144	6.93e-154	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	N-(5'phosphoribosyl)anthranilate (PRA) isomerase
HCLPGIIE_01145	1.35e-282	-	4.2.1.20	-	E	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HCLPGIIE_01146	1.23e-184	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HCLPGIIE_01147	1.29e-187	-	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	2Fe-2S iron-sulfur cluster binding domain
HCLPGIIE_01148	0.0	-	1.3.5.1, 1.3.5.4	-	C	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	Fumarate reductase flavoprotein C-term
HCLPGIIE_01149	4.83e-163	-	-	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002	-
HCLPGIIE_01150	8.94e-56	-	-	-	-	-	-	-	-
HCLPGIIE_01151	1.43e-194	-	-	-	S	ko:K07051	-	ko00000	TatD related DNase
HCLPGIIE_01152	1.24e-47	XK27_09985	-	-	S	-	-	-	Protein of unknown function (DUF1232)
HCLPGIIE_01153	0.000114	-	-	-	-	-	-	-	-
HCLPGIIE_01154	2.02e-163	-	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
HCLPGIIE_01155	1.11e-261	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HCLPGIIE_01156	3.19e-264	gcvT	2.1.2.10	-	E	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Aminomethyltransferase folate-binding domain
HCLPGIIE_01157	6.67e-86	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
HCLPGIIE_01158	0.0	gcvP	1.4.4.2	-	E	ko:K00281	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HCLPGIIE_01159	1.53e-241	-	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Amidohydrolase
HCLPGIIE_01160	8.17e-159	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
HCLPGIIE_01161	1.42e-289	-	-	-	L	-	-	-	helicase superfamily c-terminal domain
HCLPGIIE_01162	3.46e-110	ruvC	3.1.22.4	-	L	ko:K01159	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
HCLPGIIE_01163	5.71e-121	-	-	-	-	-	-	-	-
HCLPGIIE_01164	0.0	sepA	-	-	Q	-	-	-	COG2015, Alkyl sulfatase and related hydrolases
HCLPGIIE_01166	9.05e-85	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	4'-phosphopantetheinyl transferase superfamily
HCLPGIIE_01167	5.64e-173	pdxJ	2.6.99.2	-	H	ko:K03474	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HCLPGIIE_01168	0.0	-	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	AICARFT/IMPCHase bienzyme
HCLPGIIE_01169	1.06e-94	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L9, N-terminal domain
HCLPGIIE_01170	1.81e-227	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HCLPGIIE_01173	0.0	-	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	C-terminal, D2-small domain, of ClpB protein
HCLPGIIE_01176	0.0	-	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Glycosyl hydrolases family 35
HCLPGIIE_01177	1.91e-159	-	-	-	M	ko:K16079	-	ko00000,ko02000	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HCLPGIIE_01178	7.01e-308	-	3.5.4.28, 3.5.4.31	-	F	ko:K12960	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Amidohydrolase family
HCLPGIIE_01179	0.0	-	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HCLPGIIE_01180	0.0	-	2.1.1.13	-	E	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	B12 binding domain
HCLPGIIE_01181	3.59e-270	-	2.1.1.13	-	E	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	B12 binding domain
HCLPGIIE_01183	2.8e-136	-	-	-	Q	-	-	-	PA14
HCLPGIIE_01185	2.42e-194	-	3.4.16.4	-	M	ko:K03587	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011,ko03036	Penicillin-binding Protein dimerisation domain
HCLPGIIE_01186	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HCLPGIIE_01187	0.0	-	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Mur ligase middle domain
HCLPGIIE_01188	1.15e-260	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HCLPGIIE_01189	3.26e-311	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HCLPGIIE_01190	5.67e-137	-	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Phospholipase D. Active site motifs.
HCLPGIIE_01191	0.0	-	4.1.1.3	-	C	ko:K01571	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	HMGL-like
HCLPGIIE_01193	0.0	-	-	-	V	ko:K03327	-	ko00000,ko02000	MatE
HCLPGIIE_01194	2.04e-254	-	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Iron-sulfur cluster assembly protein
HCLPGIIE_01196	1.59e-270	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Iron-containing alcohol dehydrogenase
HCLPGIIE_01197	1.66e-75	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HCLPGIIE_01198	5.39e-224	-	-	-	G	-	-	-	pfkB family carbohydrate kinase
HCLPGIIE_01199	0.0	fabZ	3.5.1.108, 4.2.1.59	-	IM	ko:K16363	ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis
HCLPGIIE_01201	0.0	-	3.2.1.52	GH20	G	ko:K01207,ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko01501,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map01501,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycoside hydrolase, family 20, catalytic core
HCLPGIIE_01202	1.2e-299	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HCLPGIIE_01203	8e-226	-	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Quinolinate synthetase A protein
HCLPGIIE_01204	2.41e-55	-	-	-	S	-	-	-	Putative S-adenosyl-L-methionine-dependent methyltransferase
HCLPGIIE_01205	7.68e-172	-	-	-	S	-	-	-	Putative S-adenosyl-L-methionine-dependent methyltransferase
HCLPGIIE_01206	0.0	-	-	-	M	-	-	-	Peptidase M60-like family
HCLPGIIE_01207	2.21e-245	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HCLPGIIE_01208	0.0	-	-	-	KT	-	-	-	Sigma factor PP2C-like phosphatases
HCLPGIIE_01209	5.45e-162	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70 region 2
HCLPGIIE_01212	7.97e-108	-	2.2.1.6	-	E	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	ACT domain
HCLPGIIE_01213	0.0	-	-	-	O	-	-	-	Trypsin
HCLPGIIE_01214	1.71e-207	-	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III, delta subunit
HCLPGIIE_01215	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HCLPGIIE_01216	4.84e-63	-	-	-	P	ko:K03281	-	ko00000	Voltage gated chloride channel
HCLPGIIE_01217	6.81e-251	-	-	-	L	-	-	-	Transposase IS200 like
HCLPGIIE_01219	0.0	-	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
HCLPGIIE_01220	5.95e-263	-	2.4.1.182	GT19	M	ko:K00748	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HCLPGIIE_01221	3.89e-149	dedA	-	-	S	-	-	-	FtsZ-dependent cytokinesis
HCLPGIIE_01223	1.1e-288	-	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
HCLPGIIE_01224	6.89e-168	-	-	-	T	ko:K07657	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
HCLPGIIE_01225	0.0	-	4.2.1.9	-	EG	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Dehydratase family
HCLPGIIE_01228	0.0	-	2.6.1.66	-	E	ko:K00835	ko00290,ko01100,ko01110,ko01130,map00290,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko01007	Aminotransferase class I and II
HCLPGIIE_01229	6.08e-195	-	-	-	S	-	-	-	Domain of unknown function (DUF1732)
HCLPGIIE_01230	4.39e-145	-	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase homologues.
HCLPGIIE_01231	0.0	-	-	-	P	-	-	-	Citrate transporter
HCLPGIIE_01232	7.58e-209	-	-	-	J	ko:K01894	-	ko00000,ko01000,ko01007,ko03016	tRNA synthetases class I (E and Q), catalytic domain
HCLPGIIE_01235	8.52e-215	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
HCLPGIIE_01236	1.56e-169	-	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Type I 3-dehydroquinase
HCLPGIIE_01238	3.21e-217	-	-	-	-	-	-	-	-
HCLPGIIE_01239	1.24e-163	-	-	-	S	ko:K05810	-	ko00000,ko01000	Multi-copper polyphenol oxidoreductase laccase
HCLPGIIE_01240	2.59e-172	-	-	-	T	-	-	-	Outer membrane lipoprotein-sorting protein
HCLPGIIE_01241	1.96e-226	-	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
HCLPGIIE_01242	0.0	secD	-	-	U	ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HCLPGIIE_01244	7.92e-270	-	3.4.23.43	-	NOU	ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	Type IV leader peptidase family
HCLPGIIE_01245	1.38e-257	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Possible lysine decarboxylase
HCLPGIIE_01246	2.95e-262	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HCLPGIIE_01247	4.19e-87	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HCLPGIIE_01248	2.55e-216	-	2.3.1.39	-	I	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Acyl transferase domain
HCLPGIIE_01251	9.75e-162	-	-	-	S	-	-	-	HAD-hyrolase-like
HCLPGIIE_01252	1.14e-281	-	-	-	S	ko:K11720	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Predicted permease YjgP/YjgQ family
HCLPGIIE_01253	4.74e-266	-	-	-	E	-	-	-	serine-type peptidase activity
HCLPGIIE_01256	0.0	poxB	1.2.3.3, 1.2.5.1	-	EH	ko:K00156,ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Thiamine pyrophosphate enzyme, central domain
HCLPGIIE_01257	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HCLPGIIE_01258	2.15e-180	-	-	-	L	ko:K10800	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	uracil-dna glycosylase
HCLPGIIE_01259	9.42e-221	-	2.7.1.11	-	G	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Phosphofructokinase
HCLPGIIE_01260	5.96e-268	-	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Male sterility protein
HCLPGIIE_01261	9.53e-206	-	2.7.7.24	-	M	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HCLPGIIE_01263	0.0	-	-	-	C	-	-	-	Acetyl-CoA hydrolase/transferase C-terminal domain
HCLPGIIE_01264	7.79e-191	-	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Biotin/lipoate A/B protein ligase family
HCLPGIIE_01265	0.0	-	4.1.1.3	-	C	ko:K01572	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	Na+-transporting oxaloacetate decarboxylase beta subunit
HCLPGIIE_01266	3.5e-52	-	-	-	I	-	-	-	PFAM biotin lipoyl attachment domain-containing protein
HCLPGIIE_01268	0.0	-	2.1.3.15, 6.4.1.3	-	I	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Carboxyl transferase domain
HCLPGIIE_01269	3.39e-99	-	5.1.99.1	-	E	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Glyoxalase-like domain
HCLPGIIE_01270	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
HCLPGIIE_01271	8.14e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HCLPGIIE_01275	0.0	-	-	-	S	-	-	-	acetyltransferases and hydrolases with the alpha beta hydrolase fold
HCLPGIIE_01276	6.1e-295	-	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HCLPGIIE_01277	1.05e-112	-	-	-	P	-	-	-	Rhodanese-like domain
HCLPGIIE_01278	9.37e-150	-	-	-	S	-	-	-	Protein of unknown function (DUF1573)
HCLPGIIE_01279	1.44e-66	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	Signal peptidase (SPase) II
HCLPGIIE_01280	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HCLPGIIE_01281	3.16e-236	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HCLPGIIE_01282	6.93e-154	-	1.5.1.34	-	C	ko:K10679	ko00633,ko01120,map00633,map01120	ko00000,ko00001,ko01000	Nitroreductase family
HCLPGIIE_01283	5.93e-261	-	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
HCLPGIIE_01287	0.0	secD	-	-	U	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HCLPGIIE_01288	1.2e-222	-	-	-	S	ko:K11941	-	ko00000,ko01000	transferase activity, transferring acyl groups other than amino-acyl groups
HCLPGIIE_01291	4.95e-94	-	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	RNA cap guanine-N2 methyltransferase
HCLPGIIE_01292	1.43e-192	-	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	RNA cap guanine-N2 methyltransferase
HCLPGIIE_01293	1.49e-207	-	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
HCLPGIIE_01294	3.15e-230	-	4.2.1.113	-	M	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Mandelate Racemase Muconate Lactonizing
HCLPGIIE_01295	1.51e-270	-	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	16S rRNA methyltransferase RsmB/F
HCLPGIIE_01296	1.33e-175	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HCLPGIIE_01297	5.26e-164	-	-	-	NU	-	-	-	Prokaryotic N-terminal methylation motif
HCLPGIIE_01298	3.73e-143	-	-	-	-	-	-	-	-
HCLPGIIE_01299	0.0	-	3.1.6.1	-	P	ko:K01130	ko00140,ko00600,map00140,map00600	ko00000,ko00001,ko01000	Sulfatase
HCLPGIIE_01301	0.0	-	-	-	-	-	-	-	-
HCLPGIIE_01304	1.24e-298	-	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	tRNA (Uracil-5-)-methyltransferase
HCLPGIIE_01305	0.0	miaB	2.8.4.3	-	J	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HCLPGIIE_01306	0.0	-	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein
HCLPGIIE_01307	4.47e-256	-	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
HCLPGIIE_01308	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
HCLPGIIE_01309	4.52e-199	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HCLPGIIE_01310	5.79e-306	-	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HCLPGIIE_01311	0.0	-	-	-	-	-	-	-	-
HCLPGIIE_01312	7.16e-163	-	-	-	S	-	-	-	SWIM zinc finger
HCLPGIIE_01313	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Argininosuccinate lyase C-terminal
HCLPGIIE_01314	0.0	-	-	-	U	ko:K03321	-	ko00000,ko02000	Sulfate permease family
HCLPGIIE_01315	7.2e-125	-	-	-	-	-	-	-	-
HCLPGIIE_01316	1.04e-109	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HCLPGIIE_01318	0.0	-	-	-	S	-	-	-	Carbohydrate esterase, sialic acid-specific acetylesterase
HCLPGIIE_01322	1.02e-232	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HCLPGIIE_01323	1.06e-127	-	-	-	-	-	-	-	-
HCLPGIIE_01324	5.41e-253	-	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HCLPGIIE_01325	1.15e-151	-	-	-	NU	-	-	-	Prokaryotic N-terminal methylation motif
HCLPGIIE_01326	5.99e-80	-	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase SecG subunit
HCLPGIIE_01327	9e-65	panD	4.1.1.11	-	H	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HCLPGIIE_01328	1.6e-163	-	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin kinase
HCLPGIIE_01329	2.83e-144	-	-	-	-	-	-	-	-
HCLPGIIE_01331	0.0	-	-	-	S	-	-	-	Bacteriophage head to tail connecting protein
HCLPGIIE_01333	1.01e-178	-	-	-	-	-	-	-	-
HCLPGIIE_01335	1.86e-114	-	-	-	CO	-	-	-	cell redox homeostasis
HCLPGIIE_01336	3.44e-201	-	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Cytidylyltransferase family
HCLPGIIE_01337	0.0	-	3.6.4.13	-	L	ko:K03579	-	ko00000,ko01000	ATP-dependent helicase C-terminal
HCLPGIIE_01342	0.0	pmp21	-	-	T	-	-	-	pathogenesis
HCLPGIIE_01343	0.0	-	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	4-alpha-glucanotransferase
HCLPGIIE_01345	1.33e-228	-	-	-	S	-	-	-	Protein of unknown function (DUF1194)
HCLPGIIE_01346	4.66e-133	-	-	-	-	-	-	-	-
HCLPGIIE_01347	8.84e-211	-	-	-	S	-	-	-	Protein of unknown function DUF58
HCLPGIIE_01348	4.11e-227	-	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
HCLPGIIE_01349	7.53e-18	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HCLPGIIE_01350	2.08e-240	BT0173	-	-	S	-	-	-	Psort location Cytoplasmic, score
HCLPGIIE_01351	1.06e-169	BT0174	-	-	C	ko:K04488	-	ko00000	iron-sulfur transferase activity
HCLPGIIE_01352	6.98e-201	lpxG	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase
HCLPGIIE_01354	2.38e-99	cysJ	1.8.1.2	-	C	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	hydroxylamine reductase activity
HCLPGIIE_01356	8.31e-81	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HCLPGIIE_01357	1.14e-72	-	-	-	S	-	-	-	Glycosyl hydrolase 108
HCLPGIIE_01360	4.83e-198	-	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	ParB-like nuclease domain
HCLPGIIE_01361	1.23e-226	-	-	-	S	-	-	-	Peptidase family M28
HCLPGIIE_01363	2.2e-240	-	-	-	P	ko:K03306	-	ko00000	phosphate transporter
HCLPGIIE_01364	3.25e-309	-	-	-	O	-	-	-	peroxiredoxin activity
HCLPGIIE_01365	0.0	-	2.7.7.19	-	J	ko:K00970	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Poly A polymerase head domain
HCLPGIIE_01367	1.97e-316	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HCLPGIIE_01368	0.0	-	-	-	H	-	-	-	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HCLPGIIE_01369	0.0	-	3.4.24.3	-	NU	ko:K01387	-	ko00000,ko01000,ko01002,ko02042	translation initiation factor activity
HCLPGIIE_01370	1.19e-111	-	-	-	M	-	-	-	Transglycosylase
HCLPGIIE_01371	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HCLPGIIE_01372	4.69e-79	rsfS	-	-	S	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HCLPGIIE_01373	7.74e-141	-	-	-	D	ko:K03466	-	ko00000,ko03036	Ftsk_gamma
HCLPGIIE_01374	8.78e-16	-	-	-	-	-	-	-	-
HCLPGIIE_01376	5.52e-24	-	-	-	V	-	-	-	MacB-like periplasmic core domain
HCLPGIIE_01377	9.1e-317	-	-	-	MU	-	-	-	Outer membrane efflux protein
HCLPGIIE_01378	3.71e-283	-	-	-	V	-	-	-	Beta-lactamase
HCLPGIIE_01379	0.0	-	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HCLPGIIE_01380	5.75e-281	mtrC	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HCLPGIIE_01381	2.91e-94	-	-	-	K	-	-	-	DNA-binding transcription factor activity
HCLPGIIE_01382	1.84e-167	-	-	-	S	-	-	-	Uncharacterised protein family UPF0066
HCLPGIIE_01383	3.91e-306	-	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Dihydro-orotase-like
HCLPGIIE_01384	1.55e-222	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain
HCLPGIIE_01385	7.07e-107	-	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Phosphoribosyl transferase domain
HCLPGIIE_01386	5.31e-90	-	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	AIR carboxylase
HCLPGIIE_01388	0.0	-	-	-	H	ko:K07137	-	ko00000	5-formyltetrahydrofolate cyclo-ligase activity
HCLPGIIE_01389	1.29e-258	-	3.5.3.12	-	E	ko:K10536	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	Porphyromonas-type peptidyl-arginine deiminase
HCLPGIIE_01390	2.11e-89	-	-	-	-	-	-	-	-
HCLPGIIE_01391	2.92e-38	rseP	3.4.21.116	-	M	ko:K06399,ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	metalloendopeptidase activity
HCLPGIIE_01392	1.18e-247	rseP	3.4.21.116	-	M	ko:K06399,ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	metalloendopeptidase activity
HCLPGIIE_01393	6.17e-284	-	-	-	S	-	-	-	AI-2E family transporter
HCLPGIIE_01394	0.0	-	-	-	P	-	-	-	Domain of unknown function
HCLPGIIE_01396	5.7e-112	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
HCLPGIIE_01397	1.2e-307	-	-	-	G	-	-	-	cellulose 1,4-beta-cellobiosidase activity
HCLPGIIE_01398	4.7e-187	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HCLPGIIE_01400	7.48e-162	-	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	protein tyrosine phosphatase activity
HCLPGIIE_01401	0.0	gumC	-	-	DM	ko:K16554	ko05111,map05111	ko00000,ko00001,ko02000	PFAM lipopolysaccharide biosynthesis protein
HCLPGIIE_01402	8.07e-180	-	-	-	M	ko:K01991	ko02026,map02026	ko00000,ko00001,ko02000	polysaccharide export
HCLPGIIE_01403	6.07e-201	-	-	-	S	-	-	-	Glycosyltransferase like family 2
HCLPGIIE_01404	1.77e-225	-	-	-	S	-	-	-	Glycosyl transferase family 11
HCLPGIIE_01405	1.34e-271	-	-	GT2	S	ko:K19427	-	ko00000,ko01000	PFAM glycosyl transferase family 2
HCLPGIIE_01407	2.14e-258	-	-	-	H	-	-	-	PFAM glycosyl transferase family 8
HCLPGIIE_01408	0.0	-	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Polyphosphate kinase middle domain
HCLPGIIE_01409	0.0	-	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	Ppx/GppA phosphatase family
HCLPGIIE_01410	3.55e-258	-	-	-	S	ko:K11941	-	ko00000,ko01000	transferase activity, transferring acyl groups other than amino-acyl groups
HCLPGIIE_01411	6.15e-191	map	3.4.11.18	-	J	ko:K01265	-	ko00000,ko01000,ko01002	Metallopeptidase family M24
HCLPGIIE_01412	1.76e-152	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HCLPGIIE_01413	0.0	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HCLPGIIE_01415	6.42e-101	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A
HCLPGIIE_01416	3.38e-102	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HCLPGIIE_01417	6.82e-74	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HCLPGIIE_01418	9.16e-105	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HCLPGIIE_01419	4.08e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HCLPGIIE_01420	5.36e-138	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HCLPGIIE_01421	1.53e-47	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal proteins 50S L24/mitochondrial 39S L24
HCLPGIIE_01422	2.33e-205	nadK	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HCLPGIIE_01423	2.07e-123	-	-	-	M	ko:K03642	-	ko00000	Lytic transglycolase
HCLPGIIE_01424	0.0	-	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
HCLPGIIE_01425	1.44e-315	-	2.7.11.1	-	L	ko:K08282	-	ko00000,ko01000	SNF2 Helicase protein
HCLPGIIE_01426	2.15e-249	-	2.7.11.1	-	L	ko:K08282	-	ko00000,ko01000	SNF2 Helicase protein
HCLPGIIE_01427	0.0	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HCLPGIIE_01430	1.65e-56	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HCLPGIIE_01432	5.73e-120	-	-	-	-	-	-	-	-
HCLPGIIE_01433	3.54e-185	-	-	-	H	ko:K22132	-	ko00000,ko03016	ThiF family
HCLPGIIE_01435	1.45e-190	-	-	-	S	ko:K09769	-	ko00000	YmdB-like protein
HCLPGIIE_01436	1.56e-103	-	-	-	T	-	-	-	Universal stress protein family
HCLPGIIE_01437	2.51e-234	-	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class I (W and Y)
HCLPGIIE_01438	1.5e-196	-	-	-	GM	-	-	-	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HCLPGIIE_01439	1.19e-162	-	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
HCLPGIIE_01440	7.71e-85	-	-	-	S	ko:K09117	-	ko00000	Yqey-like protein
HCLPGIIE_01441	1.28e-223	-	-	-	CO	-	-	-	amine dehydrogenase activity
HCLPGIIE_01442	6.77e-136	-	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	HMGL-like
HCLPGIIE_01443	5.26e-201	-	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	HMGL-like
HCLPGIIE_01444	2.46e-215	-	-	-	Q	-	-	-	Fumarylacetoacetate (FAA) hydrolase family
HCLPGIIE_01445	8.7e-76	-	-	-	P	ko:K03972	-	ko00000	Rhodanese Homology Domain
HCLPGIIE_01446	0.0	-	3.2.1.50	-	G	ko:K01205	ko00531,ko01100,ko04142,map00531,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko04147	Alpha-L-fucosidase
HCLPGIIE_01447	0.0	-	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	C-terminal, D2-small domain, of ClpB protein
HCLPGIIE_01448	9.58e-245	-	2.7.14.1	-	E	ko:K19405	-	ko00000,ko01000	ATP:guanido phosphotransferase, C-terminal catalytic domain
HCLPGIIE_01449	5.46e-126	-	-	-	S	ko:K19411	-	ko00000	UvrB/uvrC motif
HCLPGIIE_01450	4.02e-57	-	-	-	P	ko:K09819	-	ko00000,ko00002,ko02000	FecCD transport family
HCLPGIIE_01451	3.01e-100	-	-	-	P	ko:K09819	-	ko00000,ko00002,ko02000	FecCD transport family
HCLPGIIE_01452	3.43e-189	-	-	-	P	ko:K09820	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HCLPGIIE_01453	3e-93	-	-	-	-	-	-	-	-
HCLPGIIE_01454	8.52e-219	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Zinc-uptake complex component A periplasmic
HCLPGIIE_01455	0.0	hyl	2.3.1.48, 3.2.1.169, 3.2.1.35	GH84	G	ko:K01197,ko:K15719	ko00531,ko01100,ko04931,map00531,map01100,map04931	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	beta-N-acetylhexosaminidase activity
HCLPGIIE_01456	3.9e-306	-	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HCLPGIIE_01457	4.86e-110	msrB	1.8.4.11, 1.8.4.12	-	O	ko:K07305,ko:K12267	-	ko00000,ko01000	peptide-methionine (R)-S-oxide reductase activity
HCLPGIIE_01458	4.86e-258	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HCLPGIIE_01459	1.84e-298	nupG	-	-	G	ko:K03289,ko:K03301,ko:K08218,ko:K11537	ko01501,map01501	ko00000,ko00001,ko00002,ko02000	Major facilitator Superfamily
HCLPGIIE_01460	4.22e-23	-	-	-	M	ko:K13730	ko05100,map05100	ko00000,ko00001	leucine-rich repeat-containing protein typical subtype
HCLPGIIE_01461	0.0	-	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Collagenase
HCLPGIIE_01462	6.75e-98	-	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Mur ligase middle domain
HCLPGIIE_01465	7.13e-110	-	-	-	S	-	-	-	Acetyltransferase (GNAT) family
HCLPGIIE_01466	1.21e-134	-	-	-	C	-	-	-	Nitroreductase family
HCLPGIIE_01467	0.0	-	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence
HCLPGIIE_01468	1.66e-87	-	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
HCLPGIIE_01470	3.22e-103	-	-	-	S	-	-	-	Protein of unknown function (DUF721)
HCLPGIIE_01471	1.33e-51	-	-	-	C	-	-	-	4Fe-4S single cluster domain of Ferredoxin I
HCLPGIIE_01472	0.0	-	-	GT2	M	ko:K03820	-	ko00000,ko01000	Carbon-nitrogen hydrolase
HCLPGIIE_01473	3.15e-176	-	-	-	S	-	-	-	Phosphodiester glycosidase
HCLPGIIE_01474	5.63e-98	-	2.7.7.13	-	JM	ko:K00966	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
HCLPGIIE_01477	5.83e-30	-	-	-	M	-	-	-	D-alanyl-D-alanine carboxypeptidase
HCLPGIIE_01481	5.06e-200	-	3.1.26.4	-	L	ko:K03471	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HII
HCLPGIIE_01482	1.9e-62	-	-	-	L	-	-	-	bacterial (prokaryotic) histone like domain
HCLPGIIE_01489	1.45e-49	-	-	-	U	ko:K03561	-	ko00000,ko02000	MotA/TolQ/ExbB proton channel family
HCLPGIIE_01491	0.0	fhs	6.3.4.3	-	H	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Formate--tetrahydrofolate ligase
HCLPGIIE_01492	4.04e-140	-	-	-	S	ko:K09974	-	ko00000	Domain of unknown function (DUF1287)
HCLPGIIE_01493	1.18e-313	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain
HCLPGIIE_01494	6.38e-151	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HCLPGIIE_01495	2.31e-194	panC	6.3.2.1	-	H	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HCLPGIIE_01496	1.65e-117	-	-	-	M	ko:K06142	-	ko00000	Outer membrane protein (OmpH-like)
HCLPGIIE_01497	5.68e-188	lpxD	2.3.1.191	-	M	ko:K02536	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HCLPGIIE_01498	4.89e-196	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HCLPGIIE_01499	5.69e-190	-	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HCLPGIIE_01500	6.06e-251	-	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	NMT1/THI5 like
HCLPGIIE_01502	3.94e-225	hyl	2.3.1.48, 3.2.1.169, 3.2.1.35	GH84	G	ko:K01197,ko:K15719	ko00531,ko01100,ko04931,map00531,map01100,map04931	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	beta-N-acetylhexosaminidase activity
HCLPGIIE_01503	2.54e-117	-	3.1.3.82, 3.1.3.83	-	E	ko:K03273	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Polynucleotide kinase 3 phosphatase
HCLPGIIE_01504	2.36e-130	-	5.3.1.28	-	G	ko:K03271	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	SIS domain
HCLPGIIE_01505	0.0	-	2.7.1.167, 2.7.7.70	-	M	ko:K03272	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	pfkB family carbohydrate kinase
HCLPGIIE_01506	1.06e-44	-	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S21
HCLPGIIE_01507	4.27e-311	hemL	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
HCLPGIIE_01508	1.28e-254	-	-	-	S	-	-	-	ankyrin repeats
HCLPGIIE_01509	0.0	-	-	-	EGP	-	-	-	Sugar (and other) transporter
HCLPGIIE_01510	0.0	-	-	-	-	-	-	-	-
HCLPGIIE_01511	0.0	glnS	6.1.1.18	-	J	ko:K01886	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class I (E and Q), anti-codon binding domain
HCLPGIIE_01512	4.56e-286	-	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase II
HCLPGIIE_01513	1.12e-99	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HCLPGIIE_01514	3.55e-200	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HCLPGIIE_01515	0.0	-	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HCLPGIIE_01516	3.6e-145	-	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	CDP-alcohol phosphatidyltransferase
HCLPGIIE_01518	0.0	hppA	3.6.1.1	-	C	ko:K15987	ko00190,map00190	ko00000,ko00001,ko01000	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane
HCLPGIIE_01523	4.34e-264	-	-	GT4	M	ko:K16703	-	ko00000,ko01000,ko01003	transferase activity, transferring glycosyl groups
HCLPGIIE_01525	0.0	-	-	-	M	-	-	-	pathogenesis
HCLPGIIE_01526	9.03e-103	-	-	-	J	-	-	-	YjgF/chorismate_mutase-like, putative endoribonuclease
HCLPGIIE_01528	8.85e-114	-	-	-	S	ko:K03748	-	ko00000	DUF218 domain
HCLPGIIE_01530	9.11e-84	-	-	-	S	-	-	-	mannose-ethanolamine phosphotransferase activity
HCLPGIIE_01533	0.0	-	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	RQC
HCLPGIIE_01535	3.06e-175	-	-	-	-	-	-	-	-
HCLPGIIE_01536	3.89e-209	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HCLPGIIE_01537	2.97e-267	sucC	6.2.1.5	-	C	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HCLPGIIE_01538	1.19e-295	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HCLPGIIE_01539	2.43e-209	-	-	-	S	ko:K03453	-	ko00000	Bile acid
HCLPGIIE_01542	6.39e-71	-	-	-	-	-	-	-	-
HCLPGIIE_01543	0.0	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HCLPGIIE_01544	0.0	-	2.3.1.40, 6.2.1.20	-	IQ	ko:K05939	ko00071,ko00564,map00071,map00564	ko00000,ko00001,ko01000	AMP-binding enzyme
HCLPGIIE_01545	1.21e-49	-	-	-	T	-	-	-	pathogenesis
HCLPGIIE_01549	2.17e-213	-	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
HCLPGIIE_01550	5.7e-168	-	1.8.4.10, 1.8.4.8	-	EH	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Phosphoadenosine phosphosulfate reductase family
HCLPGIIE_01551	3.48e-216	-	2.7.7.4	-	EH	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoadenosine phosphosulfate reductase family
HCLPGIIE_01552	0.0	-	2.7.1.25, 2.7.7.4	-	P	ko:K00955	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily
HCLPGIIE_01553	6.74e-221	-	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	NMT1/THI5 like
HCLPGIIE_01554	1.18e-179	-	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HCLPGIIE_01555	1.13e-174	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HCLPGIIE_01556	0.0	-	1.8.1.2	-	P	ko:K00381	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Nitrite and sulphite reductase 4Fe-4S domain
HCLPGIIE_01558	1.8e-270	-	-	-	J	-	-	-	PFAM Endoribonuclease L-PSP
HCLPGIIE_01559	0.0	-	-	-	C	-	-	-	cytochrome C peroxidase
HCLPGIIE_01560	0.0	-	-	-	U	-	-	-	Involved in the tonB-independent uptake of proteins
HCLPGIIE_01561	4.44e-291	-	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase family U32
HCLPGIIE_01562	1.42e-142	-	-	-	C	-	-	-	lactate oxidation
HCLPGIIE_01563	0.0	-	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	DNA Topoisomerase IV
HCLPGIIE_01564	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HCLPGIIE_01565	3.07e-32	-	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
HCLPGIIE_01566	9.47e-317	-	3.1.5.1	-	F	ko:K01129	ko00230,map00230	ko00000,ko00001,ko01000	Phosphohydrolase-associated domain
HCLPGIIE_01567	5.36e-174	-	-	-	EG	-	-	-	EamA-like transporter family
HCLPGIIE_01568	4.66e-120	-	-	-	L	-	-	-	endonuclease activity
HCLPGIIE_01571	1.51e-05	-	-	-	-	-	-	-	-
HCLPGIIE_01572	0.0	-	-	-	S	ko:K07126,ko:K13582	ko04112,map04112	ko00000,ko00001	beta-lactamase activity
HCLPGIIE_01574	5.38e-31	-	-	-	M	-	-	-	lytic transglycosylase activity
HCLPGIIE_01578	3.13e-166	-	-	-	S	-	-	-	Terminase
HCLPGIIE_01583	0.0	-	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HCLPGIIE_01584	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HCLPGIIE_01585	2.36e-249	-	2.3.1.1	-	E	ko:K14682	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Acetyltransferase (GNAT) family
HCLPGIIE_01588	4.53e-115	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	nUDIX hydrolase
HCLPGIIE_01590	3.05e-235	-	2.7.1.221	-	S	ko:K07102	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Phosphotransferase enzyme family
HCLPGIIE_01591	2.95e-306	-	4.2.1.20	-	E	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HCLPGIIE_01592	4.98e-92	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HCLPGIIE_01593	7.57e-152	-	-	-	S	-	-	-	Protein of unknown function (DUF2589)
HCLPGIIE_01594	1.13e-183	-	-	-	-	-	-	-	-
HCLPGIIE_01595	1.99e-131	-	-	-	S	-	-	-	Protein of unknown function (DUF2589)
HCLPGIIE_01596	6.69e-47	-	-	-	-	-	-	-	-
HCLPGIIE_01598	1.46e-75	-	-	-	S	ko:K09954	-	ko00000	Putative quorum-sensing-regulated virulence factor
HCLPGIIE_01599	1.57e-173	-	4.2.99.20	-	I	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Alpha/beta hydrolase family
HCLPGIIE_01600	1.88e-71	-	-	-	U	ko:K05595	-	ko00000,ko02000	MarC family integral membrane protein
HCLPGIIE_01601	0.0	-	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	tail specific protease
HCLPGIIE_01602	0.0	-	-	-	E	-	-	-	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HCLPGIIE_01603	3.01e-253	-	-	-	M	ko:K07271	-	ko00000,ko01000	LICD family
HCLPGIIE_01604	5.3e-262	cobD	2.6.1.9, 2.7.7.74, 4.1.1.81	-	M	ko:K00817,ko:K04720,ko:K07281	ko00340,ko00350,ko00360,ko00400,ko00401,ko00562,ko00860,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00562,map00860,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	nucleotidyl transferase
HCLPGIIE_01605	0.0	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	myo-inosose-2 dehydratase activity
HCLPGIIE_01606	1.34e-242	-	-	-	-	-	-	-	-
HCLPGIIE_01607	9.55e-285	pgk	2.7.2.3	-	G	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Phosphoglycerate kinase
HCLPGIIE_01608	5.26e-74	-	-	-	-	-	-	-	-
HCLPGIIE_01609	0.0	-	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	DNA Topoisomerase IV
HCLPGIIE_01611	3.07e-136	-	-	-	S	-	-	-	Maltose acetyltransferase
HCLPGIIE_01612	0.0	-	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	GMP synthase C terminal domain
HCLPGIIE_01613	0.0	-	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	IMP dehydrogenase / GMP reductase domain
HCLPGIIE_01614	2.75e-11	-	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase class I and II
HCLPGIIE_01615	0.0	-	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class I (C) catalytic domain
HCLPGIIE_01616	0.0	menD	2.2.1.9	-	H	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HCLPGIIE_01617	7.03e-15	-	1.1.1.40	-	C	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Malic enzyme, NAD binding domain
HCLPGIIE_01620	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Prolyl-tRNA synthetase, C-terminal
HCLPGIIE_01621	2.04e-158	-	-	-	S	-	-	-	Peptidase family M50
HCLPGIIE_01623	3.01e-49	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal_S15
HCLPGIIE_01624	8.44e-154	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HCLPGIIE_01625	2.46e-215	-	-	-	D	ko:K19234,ko:K19236	ko01503,map01503	ko00000,ko00001,ko01002,ko01011	ErfK ybiS ycfS ynhG family protein
HCLPGIIE_01626	0.0	-	-	-	S	-	-	-	Terminase
HCLPGIIE_01630	8.81e-200	-	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HCLPGIIE_01631	2.56e-145	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HCLPGIIE_01632	9.86e-168	-	-	-	M	-	-	-	Peptidase family M23
HCLPGIIE_01633	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	PFAM coagulation factor 5 8 type domain protein
HCLPGIIE_01634	1.33e-174	-	-	-	NU	-	-	-	Prepilin-type N-terminal cleavage methylation domain
HCLPGIIE_01636	8.16e-179	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HCLPGIIE_01637	0.0	-	-	-	S	-	-	-	Type I phosphodiesterase / nucleotide pyrophosphatase
HCLPGIIE_01638	0.0	-	-	-	G	-	-	-	beta-N-acetylhexosaminidase activity
HCLPGIIE_01639	2.13e-56	-	6.3.3.3	-	H	ko:K01935	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	AAA domain
HCLPGIIE_01640	2.5e-289	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HCLPGIIE_01641	2.79e-108	-	-	-	S	-	-	-	Putative zinc- or iron-chelating domain
HCLPGIIE_01642	1.03e-30	-	-	-	S	ko:K07126	-	ko00000	Sel1-like repeats.
HCLPGIIE_01648	1.65e-314	-	-	-	C	ko:K00185	-	ko00000	Polysulphide reductase, NrfD
HCLPGIIE_01649	4.03e-116	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HCLPGIIE_01650	3.85e-194	-	2.7.8.8	-	I	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	CDP-alcohol phosphatidyltransferase
HCLPGIIE_01651	2.34e-119	-	-	-	-	-	-	-	-
HCLPGIIE_01652	2.15e-198	-	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HCLPGIIE_01653	3.44e-144	-	-	-	H	-	-	-	HD superfamily hydrolase involved in NAD metabolism
HCLPGIIE_01654	1.61e-96	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HCLPGIIE_01655	0.0	-	-	-	S	ko:K07263	-	ko00000,ko01000,ko01002	Insulinase (Peptidase family M16)
HCLPGIIE_01657	2.16e-150	-	-	-	L	-	-	-	Membrane
HCLPGIIE_01658	0.0	-	-	-	P	ko:K01138	-	ko00000,ko01000	PA14 domain
HCLPGIIE_01659	0.0	-	3.6.4.13	-	L	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DbpA RNA binding domain
HCLPGIIE_01660	1.84e-177	-	-	-	-	-	-	-	-
HCLPGIIE_01661	0.0	-	3.1.1.53	-	E	ko:K05970	-	ko00000,ko01000	Carbohydrate esterase, sialic acid-specific acetylesterase
HCLPGIIE_01662	5.92e-235	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
HCLPGIIE_01663	2.41e-101	-	-	-	S	ko:K15977	-	ko00000	DoxX
HCLPGIIE_01664	6.75e-245	-	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	AIR synthase related protein, N-terminal domain
HCLPGIIE_01665	0.0	-	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HCLPGIIE_01666	1.47e-138	-	-	-	K	ko:K03088	-	ko00000,ko03021	ECF sigma factor
HCLPGIIE_01668	1.77e-203	-	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
HCLPGIIE_01669	1.31e-81	-	-	-	DJ	-	-	-	Addiction module toxin, RelE StbE family
HCLPGIIE_01670	8.37e-126	-	4.1.1.36	-	H	ko:K01598	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Flavoprotein
HCLPGIIE_01672	1.05e-255	-	-	-	M	-	-	-	Peptidase family M23
HCLPGIIE_01673	0.0	-	-	-	S	-	-	-	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
HCLPGIIE_01680	2.99e-43	-	-	-	-	-	-	-	-
HCLPGIIE_01683	3.44e-107	-	-	-	E	-	-	-	PFAM lipolytic protein G-D-S-L family
HCLPGIIE_01684	0.0	-	-	-	EG	-	-	-	BNR repeat-like domain
HCLPGIIE_01685	0.0	legA	3.5.1.2	-	G	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	response to abiotic stimulus
HCLPGIIE_01686	1.01e-199	supH	-	-	Q	-	-	-	phosphatase activity
HCLPGIIE_01688	5.49e-85	nuoA	1.6.5.3	-	C	ko:K00330	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HCLPGIIE_01689	1.75e-276	-	-	-	G	-	-	-	Major Facilitator Superfamily
HCLPGIIE_01693	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HCLPGIIE_01694	2.91e-38	-	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L35
HCLPGIIE_01695	5.25e-79	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HCLPGIIE_01696	0.0	-	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	Peptidase family M50
HCLPGIIE_01699	0.0	-	-	-	L	-	-	-	UvrD/REP helicase N-terminal domain
HCLPGIIE_01700	0.0	-	-	-	L	-	-	-	PD-(D/E)XK nuclease superfamily
HCLPGIIE_01701	5.62e-180	glnA	6.3.1.2	-	S	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HCLPGIIE_01702	1.51e-313	glnA	6.3.1.2	-	S	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HCLPGIIE_01705	1.28e-227	lipA	2.8.1.8	-	H	ko:K03644	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HCLPGIIE_01706	6.36e-131	tadA	3.5.4.33	-	FJ	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HCLPGIIE_01707	1.16e-240	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HCLPGIIE_01708	0.0	-	-	-	P	-	-	-	E1-E2 ATPase
HCLPGIIE_01709	0.0	-	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HCLPGIIE_01710	0.0	-	-	-	NU	ko:K02453	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02044	Bacterial type II and III secretion system protein
HCLPGIIE_01711	1.31e-244	-	-	-	-	-	-	-	-
HCLPGIIE_01712	3.24e-203	-	-	-	-	-	-	-	-
HCLPGIIE_01713	0.0	-	-	-	NU	-	-	-	Type IV pilus assembly protein PilM;
HCLPGIIE_01714	5.43e-167	-	-	-	-	-	-	-	-
HCLPGIIE_01715	5.2e-253	-	-	-	G	-	-	-	M42 glutamyl aminopeptidase
HCLPGIIE_01716	3.57e-261	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HCLPGIIE_01717	3.29e-154	-	-	-	S	-	-	-	Protein of unknown function (DUF3313)
HCLPGIIE_01718	2.79e-312	-	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	Aminopeptidase P, N-terminal domain
HCLPGIIE_01719	2.25e-206	hisG	2.4.2.17	-	E	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	ATP phosphoribosyltransferase
HCLPGIIE_01720	2.09e-10	-	-	-	S	-	-	-	Mitochondrial domain of unknown function (DUF1713)
HCLPGIIE_01723	2.88e-242	-	-	-	M	ko:K18094	ko01501,ko02020,map01501,map02020	ko00000,ko00001,ko00002,ko01504,ko02000	Biotin-lipoyl like
HCLPGIIE_01724	5.55e-175	-	2.1.1.13	-	E	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	B12 binding domain
HCLPGIIE_01725	2.36e-171	-	-	-	S	-	-	-	Putative threonine/serine exporter
HCLPGIIE_01726	1.45e-102	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HCLPGIIE_01727	1.13e-312	-	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system DNA methylase K03427
HCLPGIIE_01736	1.9e-59	-	-	-	S	-	-	-	AAA domain
HCLPGIIE_01738	0.0	-	-	-	V	-	-	-	MatE
HCLPGIIE_01739	1.24e-179	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
HCLPGIIE_01740	2.63e-84	-	-	-	M	-	-	-	Lysin motif
HCLPGIIE_01741	1.78e-202	-	-	-	L	ko:K03424	-	ko00000,ko01000	TatD related DNase
HCLPGIIE_01742	8.81e-267	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2219)
HCLPGIIE_01743	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Beta galactosidase small chain
HCLPGIIE_01744	2.66e-06	-	-	-	-	-	-	-	-
HCLPGIIE_01746	0.0	-	2.7.13.3	-	T	ko:K07646	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Osmosensitive K+ channel His kinase sensor domain
HCLPGIIE_01747	2.4e-167	-	-	-	T	ko:K07667	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
HCLPGIIE_01749	0.0	-	3.6.3.12	-	P	ko:K01546	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
HCLPGIIE_01750	0.0	-	3.6.3.12	-	P	ko:K01547	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
HCLPGIIE_01751	1.08e-127	-	3.6.3.12	-	P	ko:K01548	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
HCLPGIIE_01752	9.07e-73	-	-	-	S	-	-	-	PFAM Cupin 2 conserved barrel domain protein
HCLPGIIE_01753	1.64e-05	-	-	-	K	-	-	-	DNA-binding transcription factor activity
HCLPGIIE_01754	2.29e-222	-	-	-	-	-	-	-	-
HCLPGIIE_01755	0.0	-	-	-	P	-	-	-	Domain of unknown function (DUF4976)
HCLPGIIE_01756	0.0	-	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	RecQ zinc-binding
HCLPGIIE_01758	2.5e-300	-	-	-	M	-	-	-	Glycosyl transferases group 1
HCLPGIIE_01759	1.05e-252	-	-	-	S	-	-	-	Glycoside-hydrolase family GH114
HCLPGIIE_01760	0.0	-	1.4.3.16	-	H	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Fumarate reductase flavoprotein C-term
HCLPGIIE_01761	4.07e-133	-	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	SpoU rRNA Methylase family
HCLPGIIE_01762	3.08e-204	-	3.1.1.53	-	L	ko:K03547,ko:K05970	-	ko00000,ko01000,ko03400	3'-5' exonuclease activity
HCLPGIIE_01763	9.94e-90	-	-	-	K	-	-	-	Helix-turn-helix diphteria tox regulatory element
HCLPGIIE_01764	0.0	-	-	-	P	-	-	-	E1-E2 ATPase
HCLPGIIE_01766	2.83e-303	-	-	-	M	ko:K07267	-	ko00000,ko02000	wide pore channel activity
HCLPGIIE_01769	0.0	-	-	-	P	ko:K04759	-	ko00000,ko02000	Ferrous iron transport protein B C terminus
HCLPGIIE_01770	4.02e-48	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	iron ion homeostasis
HCLPGIIE_01771	1.13e-40	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	iron ion homeostasis
HCLPGIIE_01774	8.26e-101	-	-	-	S	ko:K07107	-	ko00000,ko01000	Thioesterase-like superfamily
HCLPGIIE_01775	1.69e-180	-	-	-	S	-	-	-	competence protein
HCLPGIIE_01776	9.83e-67	-	-	-	-	-	-	-	-
HCLPGIIE_01777	8.38e-191	-	3.6.1.66	-	S	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	MazG nucleotide pyrophosphohydrolase domain
HCLPGIIE_01778	3.68e-75	-	-	-	-	-	-	-	-
HCLPGIIE_01779	9.13e-264	-	3.1.13.5	-	J	ko:K03684	-	ko00000,ko01000,ko03016	3'-5' exonuclease
HCLPGIIE_01780	1.52e-137	-	-	-	S	ko:K07164	-	ko00000	C4-type zinc ribbon domain
HCLPGIIE_01781	1.13e-291	lpxK	2.7.1.130	-	M	ko:K00912	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)
HCLPGIIE_01782	1.99e-49	-	-	-	-	-	-	-	-
HCLPGIIE_01783	0.0	-	-	-	S	ko:K07263	-	ko00000,ko01000,ko01002	Insulinase (Peptidase family M16)
HCLPGIIE_01787	5.85e-11	-	-	-	U	-	-	-	Passenger-associated-transport-repeat
HCLPGIIE_01789	4.86e-206	-	1.4.1.16	-	S	ko:K03340	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
HCLPGIIE_01790	3.27e-171	-	-	-	S	-	-	-	peptidoglycan biosynthetic process
HCLPGIIE_01791	2.31e-33	-	-	-	F	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
HCLPGIIE_01792	2.34e-58	-	-	-	F	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
HCLPGIIE_01793	1.31e-53	-	-	-	T	-	-	-	pathogenesis
HCLPGIIE_01794	1.65e-207	-	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Thymidylate synthase
HCLPGIIE_01795	5.02e-115	-	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Dihydrofolate reductase
HCLPGIIE_01796	0.0	-	-	-	V	-	-	-	AcrB/AcrD/AcrF family
HCLPGIIE_01799	1.27e-70	-	-	-	K	-	-	-	ribonuclease III activity
HCLPGIIE_01800	2.57e-163	-	-	-	-	-	-	-	-
HCLPGIIE_01801	2.1e-140	nuoC	1.6.5.3	-	C	ko:K00332	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HCLPGIIE_01802	5.55e-133	nuoB	1.6.5.3	-	C	ko:K00331	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HCLPGIIE_01810	8.63e-188	-	5.2.1.8	-	O	ko:K03773	-	ko00000,ko01000,ko03110	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase
HCLPGIIE_01811	1.08e-138	-	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HCLPGIIE_01812	7.9e-269	-	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	Thermophilic metalloprotease (M29)
HCLPGIIE_01813	9.52e-204	-	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
HCLPGIIE_01814	0.0	-	-	-	P	ko:K03455	-	ko00000	TrkA-N domain
HCLPGIIE_01815	1.15e-165	-	-	-	L	ko:K03424	-	ko00000,ko01000	TatD related DNase
HCLPGIIE_01821	3.33e-207	-	1.1.1.262	-	H	ko:K00097	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Pyridoxal phosphate biosynthetic protein PdxA
HCLPGIIE_01824	4.59e-222	-	-	-	M	-	-	-	D-alanyl-D-alanine carboxypeptidase
HCLPGIIE_01826	1.64e-263	-	-	-	G	-	-	-	M42 glutamyl aminopeptidase
HCLPGIIE_01827	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycoside hydrolase, family 20, catalytic core
HCLPGIIE_01828	1.77e-281	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HCLPGIIE_01829	4.43e-272	-	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Alkaline phosphatase homologues
HCLPGIIE_01830	3.06e-85	-	-	-	M	ko:K03282	-	ko00000,ko02000	Large-conductance mechanosensitive channel, MscL
HCLPGIIE_01831	4.8e-313	-	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
HCLPGIIE_01832	1.2e-105	-	-	-	S	-	-	-	ACT domain protein
HCLPGIIE_01833	9.29e-132	-	-	-	J	ko:K02356	-	ko00000,ko03012	Elongation factor P (EF-P) OB domain
HCLPGIIE_01834	2e-245	-	-	-	G	-	-	-	Glycosyl hydrolases family 16
HCLPGIIE_01835	0.0	-	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
HCLPGIIE_01836	0.0	-	-	-	L	ko:K03631	-	ko00000,ko03400	RecF/RecN/SMC N terminal domain
HCLPGIIE_01837	8.73e-189	-	3.1.4.55	-	S	ko:K06167	ko00440,map00440	ko00000,ko00001,ko01000	Metallo-beta-lactamase superfamily
HCLPGIIE_01838	1.45e-191	-	-	-	M	-	-	-	Glycosyl transferase WecB/TagA/CpsF family
HCLPGIIE_01839	8.73e-171	yyaQ	-	-	V	-	-	-	Protein conserved in bacteria
HCLPGIIE_01840	1.34e-90	-	-	-	-	-	-	-	-
HCLPGIIE_01843	8.16e-207	-	-	-	S	ko:K09949	-	ko00000	Protein of unknown function (DUF1009)
HCLPGIIE_01844	1.26e-208	-	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	2-oxoacid dehydrogenases acyltransferase (catalytic domain)
HCLPGIIE_01845	0.0	rnr	-	-	K	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HCLPGIIE_01849	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Glycosyl hydrolase family 36 N-terminal domain
HCLPGIIE_01850	2.47e-53	himA	-	-	L	ko:K03530,ko:K04764,ko:K05788	-	ko00000,ko03032,ko03036,ko03400	regulation of translation
HCLPGIIE_01851	8.48e-06	-	-	-	-	-	-	-	-
HCLPGIIE_01852	7.5e-92	-	-	-	S	-	-	-	Acetyltransferase (GNAT) family
HCLPGIIE_01853	8.31e-296	-	-	-	C	-	-	-	Sulfatase-modifying factor enzyme 1
HCLPGIIE_01854	8.6e-169	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	KR domain
HCLPGIIE_01856	1.25e-283	-	-	-	S	-	-	-	very-long-chain-acyl-CoA dehydrogenase activity
HCLPGIIE_01857	1.19e-92	-	5.1.3.29	-	G	ko:K02431	-	ko00000,ko01000	RbsD / FucU transport protein family
HCLPGIIE_01861	7.03e-215	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HCLPGIIE_01862	3.25e-251	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HCLPGIIE_01863	0.0	-	-	-	S	-	-	-	Fungal chitosanase of glycosyl hydrolase group 75
HCLPGIIE_01864	9.28e-219	-	2.5.1.21	-	I	ko:K00801	ko00100,ko00909,ko01100,ko01110,ko01130,map00100,map00909,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko01006	Squalene/phytoene synthase
HCLPGIIE_01865	9.17e-202	-	-	-	KT	ko:K02584	ko02020,map02020	ko00000,ko00001,ko03000	Bacterial regulatory protein, Fis family
HCLPGIIE_01867	3.01e-113	-	1.16.3.2	-	P	ko:K02217	-	ko00000,ko01000	Ferritin-like domain
HCLPGIIE_01868	0.0	-	-	-	-	-	-	-	-
HCLPGIIE_01869	0.0	-	-	-	NU	ko:K02453	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02044	Bacterial type II and III secretion system protein
HCLPGIIE_01871	0.0	-	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase alpha chain
HCLPGIIE_01872	2.91e-220	-	1.8.1.9	-	O	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Pyridine nucleotide-disulphide oxidoreductase
HCLPGIIE_01873	1.51e-174	-	-	-	E	ko:K00612	-	ko00000,ko01000	lipolytic protein G-D-S-L family
HCLPGIIE_01874	2.05e-28	-	-	-	-	-	-	-	-
HCLPGIIE_01875	3.29e-173	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	tRNA (Guanine-1)-methyltransferase
HCLPGIIE_01876	8.8e-239	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HCLPGIIE_01877	0.0	-	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
HCLPGIIE_01878	2.17e-08	-	-	-	M	-	-	-	major outer membrane lipoprotein
HCLPGIIE_01880	4.21e-137	-	-	-	J	ko:K05808	-	ko00000,ko03009	Sigma 54 modulation/S30EA ribosomal protein C terminus
HCLPGIIE_01882	3.85e-27	corC_1	-	-	P	ko:K03699	-	ko00000,ko02042	Transporter associated domain
HCLPGIIE_01883	1.2e-158	-	-	-	IQ	-	-	-	Short chain dehydrogenase
HCLPGIIE_01884	3.23e-307	-	-	-	C	-	-	-	Carboxymuconolactone decarboxylase family
HCLPGIIE_01885	5.14e-267	-	-	-	S	ko:K06889	-	ko00000	X-Pro dipeptidyl-peptidase (S15 family)
HCLPGIIE_01886	9.71e-185	-	-	-	S	-	-	-	Alpha/beta hydrolase family
HCLPGIIE_01887	4.25e-178	-	-	-	C	-	-	-	aldo keto reductase
HCLPGIIE_01888	3.52e-80	-	-	-	K	-	-	-	Transcriptional regulator
HCLPGIIE_01889	2.97e-116	-	-	-	K	-	-	-	Transcriptional regulator
HCLPGIIE_01890	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
HCLPGIIE_01891	5.54e-303	-	-	-	C	-	-	-	4 iron, 4 sulfur cluster binding
HCLPGIIE_01892	1.02e-99	-	-	-	KT	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	phosphorelay signal transduction system
HCLPGIIE_01893	2.57e-133	-	-	-	D	-	-	-	ErfK ybiS ycfS ynhG family protein
HCLPGIIE_01894	0.0	-	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Aconitase C-terminal domain
HCLPGIIE_01895	8.8e-169	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	PFAM N-acetylmuramoyl-L-alanine amidase family 2
HCLPGIIE_01899	0.0	-	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	Bacterial DNA topoisomeraes I ATP-binding domain
HCLPGIIE_01900	2.62e-99	-	-	-	-	-	-	-	-
HCLPGIIE_01901	0.0	-	2.1.1.107, 4.2.1.75	-	H	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase HemD
HCLPGIIE_01902	2.24e-101	-	-	-	S	-	-	-	peptidase
HCLPGIIE_01903	5.18e-172	-	-	-	S	ko:K06973	-	ko00000	Putative neutral zinc metallopeptidase
HCLPGIIE_01904	4.75e-96	-	-	-	S	-	-	-	peptidase
HCLPGIIE_01905	0.0	-	-	-	S	-	-	-	pathogenesis
HCLPGIIE_01906	0.0	-	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen
HCLPGIIE_01907	2.09e-216	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HCLPGIIE_01908	8.99e-254	-	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	endonuclease III
HCLPGIIE_01909	2.65e-140	aat	2.3.2.6	-	O	ko:K00684	-	ko00000,ko01000	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
HCLPGIIE_01910	0.0	-	2.7.9.1	-	G	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Pyruvate phosphate dikinase, PEP/pyruvate binding domain
HCLPGIIE_01911	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Phosphoglucose isomerase
HCLPGIIE_01912	8e-254	-	-	-	S	-	-	-	COG0790 FOG TPR repeat, SEL1 subfamily
HCLPGIIE_01913	1.38e-214	-	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	S-adenosylmethionine-dependent methyltransferase
HCLPGIIE_01915	0.0	-	5.4.99.2	-	I	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Methylmalonyl-CoA mutase
HCLPGIIE_01916	4.74e-171	-	5.4.99.2	-	I	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Methylmalonyl-CoA mutase
HCLPGIIE_01917	2.96e-60	-	-	-	-	-	-	-	-
HCLPGIIE_01918	1.41e-244	-	-	-	NU	-	-	-	Prokaryotic N-terminal methylation motif
HCLPGIIE_01919	4.01e-182	-	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Biotin/lipoate A/B protein ligase family
HCLPGIIE_01920	7.54e-240	-	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo/keto reductase family
HCLPGIIE_01921	4.27e-95	-	4.3.1.12	-	E	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	ko00000,ko00001,ko01000	Ornithine cyclodeaminase/mu-crystallin family
HCLPGIIE_01922	0.0	-	2.7.7.15	-	H	ko:K00968	ko00440,ko00564,ko01100,ko05231,map00440,map00564,map01100,map05231	ko00000,ko00001,ko00002,ko01000	Oxidoreductase family, NAD-binding Rossmann fold
HCLPGIIE_01923	6.55e-178	-	-	-	M	ko:K07271	-	ko00000,ko01000	LICD family
HCLPGIIE_01924	4.45e-18	-	-	-	G	-	-	-	beta-N-acetylhexosaminidase activity
HCLPGIIE_01925	1.63e-313	-	-	-	G	-	-	-	beta-N-acetylhexosaminidase activity
HCLPGIIE_01926	8.08e-234	-	-	-	S	-	-	-	Acyltransferase family
HCLPGIIE_01927	0.0	-	-	-	O	-	-	-	Cytochrome C assembly protein
HCLPGIIE_01928	2.26e-105	ccs1	-	-	O	ko:K07399	-	ko00000	cytochrome c biogenesis protein
HCLPGIIE_01929	2.07e-210	fatB	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	iron ion transport
HCLPGIIE_01930	1.06e-180	yclP	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HCLPGIIE_01931	1.95e-225	fatC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	iron ion homeostasis
HCLPGIIE_01932	2.84e-215	yclN	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	iron ion homeostasis
HCLPGIIE_01933	2.63e-243	-	-	-	J	-	-	-	Endoribonuclease L-PSP
HCLPGIIE_01934	0.0	-	-	-	C	-	-	-	Di-haem oxidoreductase, putative peroxidase
HCLPGIIE_01935	2.64e-246	-	-	-	S	-	-	-	Imelysin
HCLPGIIE_01936	1.59e-142	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
HCLPGIIE_01938	2.79e-120	-	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Phosphoribosyl transferase domain
HCLPGIIE_01941	3.08e-107	-	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	6-pyruvoyl tetrahydropterin synthase
HCLPGIIE_01943	0.0	-	4.2.1.2	-	C	ko:K01676	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible hydration of fumarate to (S)- malate
HCLPGIIE_01944	0.0	-	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	ATPases associated with a variety of cellular activities
HCLPGIIE_01945	1.13e-112	-	-	-	M	-	-	-	Polymer-forming cytoskeletal
HCLPGIIE_01946	1.99e-173	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HCLPGIIE_01947	3.56e-280	-	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	S-adenosylmethionine-dependent methyltransferase
HCLPGIIE_01948	5.5e-56	-	-	-	S	ko:K06960	-	ko00000	KH domain
HCLPGIIE_01949	1.03e-11	-	-	-	-	-	-	-	-
HCLPGIIE_01950	1.02e-258	-	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HCLPGIIE_01952	1.37e-248	-	3.3.1.1	-	H	ko:K01251	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	adenosylhomocysteinase activity
HCLPGIIE_01953	1.34e-155	-	-	-	M	-	-	-	Bacterial transferase hexapeptide (six repeats)
HCLPGIIE_01955	2.25e-119	-	-	-	-	-	-	-	-
HCLPGIIE_01956	1.59e-243	-	-	-	I	-	-	-	PFAM Prenyltransferase squalene oxidase
HCLPGIIE_01959	4.95e-178	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Pyrroline-5-carboxylate reductase dimerisation
HCLPGIIE_01960	1.29e-156	-	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Methyladenine glycosylase
HCLPGIIE_01961	2.62e-209	-	-	-	S	-	-	-	ABC-type transport system involved in multi-copper enzyme maturation permease component
HCLPGIIE_01962	1.89e-226	-	-	-	S	-	-	-	Protein conserved in bacteria
HCLPGIIE_01963	4.08e-33	-	-	-	KLT	-	-	-	Tyrosine-protein kinase, subgroup, catalytic domain
HCLPGIIE_01964	4.85e-66	-	-	-	K	ko:K03827	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HCLPGIIE_01965	0.0	-	4.1.99.1	-	E	ko:K01667	ko00380,map00380	ko00000,ko00001,ko01000	Beta-eliminating lyase
HCLPGIIE_01966	5.34e-140	-	-	-	M	-	-	-	Peptidoglycan-binding domain 1 protein
HCLPGIIE_01967	8.21e-245	-	-	-	S	-	-	-	Domain of unknown function (DUF4105)
HCLPGIIE_01968	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	B3/4 domain
HCLPGIIE_01969	1.22e-222	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Aminoacyl tRNA synthetase class II, N-terminal domain
HCLPGIIE_01970	6.82e-223	-	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
HCLPGIIE_01971	2.22e-191	-	-	-	K	-	-	-	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
HCLPGIIE_01974	0.0	rsmH	2.1.1.199	-	M	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HCLPGIIE_01975	4.54e-105	-	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HCLPGIIE_01976	3.28e-187	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
HCLPGIIE_01977	2.82e-154	-	-	-	S	-	-	-	UPF0126 domain
HCLPGIIE_01978	1.61e-13	-	-	-	S	-	-	-	Mac 1
HCLPGIIE_01979	1.56e-311	mnmE	-	-	J	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HCLPGIIE_01980	2.72e-263	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HCLPGIIE_01981	1.86e-206	miaA	2.5.1.75	-	J	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HCLPGIIE_01982	2.94e-184	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
HCLPGIIE_01983	1.04e-272	-	-	-	S	ko:K11941	-	ko00000,ko01000	transferase activity, transferring acyl groups other than amino-acyl groups
HCLPGIIE_01984	3.73e-144	-	-	-	S	-	-	-	Hexapeptide repeat of succinyl-transferase
HCLPGIIE_01985	4.02e-284	-	-	-	M	-	-	-	Glycosyl transferases group 1
HCLPGIIE_01986	2.61e-288	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HCLPGIIE_01987	0.0	-	-	-	S	-	-	-	polysaccharide biosynthetic process
HCLPGIIE_01989	9.77e-259	-	-	-	S	-	-	-	PFAM glycosyl transferase family 2
HCLPGIIE_01990	3.93e-128	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
HCLPGIIE_01991	3.78e-228	-	-	-	C	-	-	-	e3 binding domain
HCLPGIIE_01992	4.34e-284	-	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HCLPGIIE_01993	4.05e-135	-	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HCLPGIIE_01994	0.0	-	-	-	EGIP	-	-	-	Phosphate acyltransferases
HCLPGIIE_01995	0.0	-	-	-	T	-	-	-	5TM C-terminal transporter carbon starvation CstA
HCLPGIIE_01996	3.4e-15	-	-	-	-	-	-	-	-
HCLPGIIE_01997	0.0	-	-	-	P	-	-	-	PA14 domain
HCLPGIIE_01998	2e-82	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HCLPGIIE_01999	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HCLPGIIE_02000	0.0	kdpB	3.6.3.12	-	P	ko:K01547	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
HCLPGIIE_02001	2.54e-132	kdpC	3.6.3.12	-	P	ko:K01548	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
HCLPGIIE_02002	3.88e-263	-	2.7.13.3	-	T	ko:K07646	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Osmosensitive K+ channel His kinase sensor domain
HCLPGIIE_02003	5.89e-46	-	2.7.11.1	-	T	ko:K08884,ko:K12132,ko:K20333	ko02024,map02024	ko00000,ko00001,ko01000,ko01001	PFAM Formylglycine-generating sulfatase enzyme
HCLPGIIE_02004	2.47e-165	-	2.7.11.1	-	T	ko:K08884,ko:K12132,ko:K20333	ko02024,map02024	ko00000,ko00001,ko01000,ko01001	PFAM Formylglycine-generating sulfatase enzyme
HCLPGIIE_02006	4.16e-196	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
HCLPGIIE_02007	1.72e-141	-	-	-	K	ko:K03088	-	ko00000,ko03021	DNA-templated transcription, initiation
HCLPGIIE_02008	0.0	-	-	-	KLT	-	-	-	Protein tyrosine kinase
HCLPGIIE_02009	1.98e-280	-	-	-	C	-	-	-	Aldo/keto reductase family
HCLPGIIE_02010	2.21e-79	-	-	-	K	-	-	-	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
HCLPGIIE_02011	1.16e-258	-	4.1.2.48	-	E	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Beta-eliminating lyase
HCLPGIIE_02012	7.08e-284	-	-	-	-	-	-	-	-
HCLPGIIE_02013	0.0	-	-	-	S	-	-	-	von Willebrand factor type A domain
HCLPGIIE_02014	0.0	-	-	-	S	-	-	-	Aerotolerance regulator N-terminal
HCLPGIIE_02015	3.33e-207	-	-	-	S	-	-	-	Protein of unknown function DUF58
HCLPGIIE_02016	0.0	-	-	-	S	-	-	-	ABC-type transport system involved in multi-copper enzyme maturation permease component
HCLPGIIE_02017	8.89e-110	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
HCLPGIIE_02018	1.47e-114	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
HCLPGIIE_02019	0.0	-	-	-	-	-	-	-	-
HCLPGIIE_02020	2.37e-234	-	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
HCLPGIIE_02021	3.72e-293	-	-	-	S	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
HCLPGIIE_02022	1.15e-239	-	-	-	E	-	-	-	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HCLPGIIE_02024	5.75e-202	-	-	-	O	-	-	-	stress-induced mitochondrial fusion
HCLPGIIE_02025	5.51e-206	-	-	-	S	ko:K07071	-	ko00000	Domain of unknown function (DUF1731)
HCLPGIIE_02026	8.5e-121	-	-	-	M	ko:K03098	-	ko00000,ko04147	Lipocalin-like domain
HCLPGIIE_02027	1.35e-236	-	1.1.1.86	-	E	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HCLPGIIE_02028	2.92e-189	-	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HCLPGIIE_02029	2.65e-150	-	-	-	K	-	-	-	Transcriptional regulator
HCLPGIIE_02030	2.22e-263	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
HCLPGIIE_02032	0.0	-	-	-	P	-	-	-	Sulfatase
HCLPGIIE_02033	2.1e-78	divIC	-	-	D	ko:K05589,ko:K13052	-	ko00000,ko03036	cell cycle
HCLPGIIE_02034	1.47e-301	-	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HCLPGIIE_02035	4.98e-29	-	-	-	E	-	-	-	Aminotransferase class I and II
HCLPGIIE_02036	0.0	-	-	-	E	-	-	-	Aminotransferase class I and II
HCLPGIIE_02037	2.15e-197	-	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HCLPGIIE_02038	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Alpha galactosidase A
HCLPGIIE_02039	1.04e-49	-	-	-	-	-	-	-	-
HCLPGIIE_02040	1.45e-55	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L28 family
HCLPGIIE_02041	8.69e-232	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
HCLPGIIE_02042	8.69e-96	-	-	-	L	ko:K07447	-	ko00000,ko01000	Likely ribonuclease with RNase H fold.
HCLPGIIE_02043	1.9e-256	-	2.7.7.13	-	M	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
HCLPGIIE_02044	6.08e-164	-	2.5.1.31	-	I	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HCLPGIIE_02045	0.0	-	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	TopoisomeraseII
HCLPGIIE_02046	4.89e-201	ispE	2.7.1.148	-	I	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	GHMP kinases N terminal domain
HCLPGIIE_02048	0.0	-	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	HELICc2
HCLPGIIE_02049	1.04e-173	cbiO	-	-	P	ko:K02006,ko:K02008,ko:K16784,ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPase activity
HCLPGIIE_02050	6.65e-193	cbiQ	-	-	P	ko:K02007,ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transmembrane transporter activity
HCLPGIIE_02051	8.77e-239	cbiM	-	-	P	ko:K02007,ko:K02009,ko:K16915	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt ion transport
HCLPGIIE_02053	7.68e-09	-	-	-	S	-	-	-	Lipocalin-like
HCLPGIIE_02055	2.8e-116	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Low molecular weight phosphatase family
HCLPGIIE_02057	6.99e-238	-	-	-	E	-	-	-	Aminotransferase class-V
HCLPGIIE_02058	2.52e-119	-	-	-	S	-	-	-	Conserved hypothetical protein 698
HCLPGIIE_02061	2.71e-58	-	-	-	T	ko:K02667	ko02020,map02020	ko00000,ko00001,ko00002,ko02022,ko02035	Bacterial regulatory protein, Fis family
HCLPGIIE_02062	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HCLPGIIE_02063	7.28e-138	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Exonuclease
HCLPGIIE_02064	6.28e-164	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HCLPGIIE_02065	0.0	-	-	-	CO	-	-	-	Disulphide bond corrector protein DsbC
HCLPGIIE_02066	7.56e-94	-	-	-	O	-	-	-	OsmC-like protein
HCLPGIIE_02068	3.42e-111	-	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	Cytidine and deoxycytidylate deaminase zinc-binding region
HCLPGIIE_02069	0.0	-	-	-	EGIP	-	-	-	Phosphate acyltransferases
HCLPGIIE_02071	8.78e-206	-	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydrogenase
HCLPGIIE_02072	0.0	-	-	-	P	ko:K02014	-	ko00000,ko02000	TonB dependent receptor
HCLPGIIE_02073	2.36e-166	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HCLPGIIE_02074	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HCLPGIIE_02076	7.54e-156	cat	2.3.1.28	-	V	ko:K19271	-	br01600,ko00000,ko01000,ko01504	Chloramphenicol acetyltransferase
HCLPGIIE_02078	2.05e-229	-	-	-	EP	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
HCLPGIIE_02079	0.0	der	-	-	S	ko:K03977	-	ko00000,ko03009	KH-domain-like of EngA bacterial GTPase enzymes, C-terminal
HCLPGIIE_02080	3.23e-249	-	-	-	S	ko:K07091	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Predicted permease YjgP/YjgQ family
HCLPGIIE_02081	1.1e-125	-	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Recombination protein O N terminal
HCLPGIIE_02082	1.14e-182	-	-	-	S	-	-	-	Tetratricopeptide repeat
HCLPGIIE_02083	0.0	dxs	2.2.1.7	-	HI	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HCLPGIIE_02084	3.08e-52	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease VII activity
HCLPGIIE_02085	0.0	-	-	-	O	-	-	-	C-terminal four TMM region of protein-O-mannosyltransferase
HCLPGIIE_02086	0.0	-	-	-	T	-	-	-	Bacterial regulatory protein, Fis family
HCLPGIIE_02087	1.82e-274	-	-	-	T	-	-	-	PAS domain
HCLPGIIE_02088	3.37e-97	-	-	-	S	ko:K07107	-	ko00000,ko01000	Thioesterase superfamily
HCLPGIIE_02089	0.0	gpmI	5.4.2.12	-	G	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	BPG-independent PGAM N-terminus (iPGM_N)
HCLPGIIE_02090	4.16e-85	-	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S12/S23
HCLPGIIE_02091	2.91e-104	-	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S7p/S5e
HCLPGIIE_02092	0.0	-	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HCLPGIIE_02093	3.67e-65	-	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S10p/S20e
HCLPGIIE_02094	3.86e-149	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HCLPGIIE_02095	9.43e-132	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L4/L1 family
HCLPGIIE_02096	8.72e-58	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HCLPGIIE_02097	1.85e-203	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HCLPGIIE_02098	1.05e-58	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HCLPGIIE_02099	4.05e-152	-	-	-	-	-	-	-	-
HCLPGIIE_02100	4.97e-70	-	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome
HCLPGIIE_02101	4.27e-155	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HCLPGIIE_02102	3.42e-97	-	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HCLPGIIE_02103	5.78e-35	-	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L29 protein
HCLPGIIE_02104	2.19e-56	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HCLPGIIE_02105	6.79e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HCLPGIIE_02106	1.63e-198	-	-	-	-	-	-	-	-
HCLPGIIE_02107	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HCLPGIIE_02108	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Domain of unknown function (DUF4982)
HCLPGIIE_02109	3.03e-250	-	5.2.1.8	-	O	ko:K03771	-	ko00000,ko01000,ko03110	SurA N-terminal domain
HCLPGIIE_02110	6.1e-170	-	2.5.1.39	-	H	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
HCLPGIIE_02111	2.21e-215	-	-	-	K	-	-	-	LysR substrate binding domain
HCLPGIIE_02114	1.38e-276	-	3.2.1.23	-	M	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
HCLPGIIE_02115	2.99e-316	-	-	-	I	-	-	-	PFAM Prenyltransferase squalene oxidase
HCLPGIIE_02116	8.42e-302	-	4.2.1.129, 5.4.99.17, 5.5.1.16	-	I	ko:K06045,ko:K17811	ko00909,ko01110,map00909,map01110	ko00000,ko00001,ko01000	PFAM Prenyltransferase squalene oxidase
HCLPGIIE_02117	9.82e-262	-	-	-	M	ko:K02022	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HCLPGIIE_02118	5.24e-159	-	-	-	S	-	-	-	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HCLPGIIE_02120	5.12e-71	-	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Thioredoxin-like domain
HCLPGIIE_02121	5.48e-296	-	-	-	-	-	-	-	-
HCLPGIIE_02122	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class II (D, K and N)
HCLPGIIE_02124	0.0	-	-	-	T	-	-	-	pathogenesis
HCLPGIIE_02125	2.14e-108	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HCLPGIIE_02126	0.0	-	-	-	M	ko:K02847,ko:K13009,ko:K16705	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	-O-antigen
HCLPGIIE_02127	8.67e-85	-	-	-	S	-	-	-	Protein of unknown function, DUF488
HCLPGIIE_02128	3.49e-212	-	2.5.1.61	-	H	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Porphobilinogen deaminase, dipyromethane cofactor binding domain
HCLPGIIE_02129	7.23e-239	hemA	1.2.1.70	-	H	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Glutamyl-tRNAGlu reductase, N-terminal domain
HCLPGIIE_02130	6.58e-175	-	-	-	S	-	-	-	Cytochrome C assembly protein
HCLPGIIE_02131	1.29e-187	folE2	3.5.4.16	-	S	ko:K09007	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Type I GTP cyclohydrolase folE2
HCLPGIIE_02132	1.2e-49	-	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S18
HCLPGIIE_02133	5.67e-33	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L33
HCLPGIIE_02134	1.61e-108	-	-	-	T	-	-	-	Prokaryotic dksA/traR C4-type zinc finger
HCLPGIIE_02135	3.27e-229	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HCLPGIIE_02136	1.7e-237	sun	2.1.1.176, 2.1.1.178	-	J	ko:K03500,ko:K11392	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HCLPGIIE_02137	3.37e-68	-	-	-	S	ko:K07095	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
HCLPGIIE_02138	3.33e-97	nudI	3.6.1.55	-	F	ko:K03574,ko:K12944	-	ko00000,ko01000,ko03400	GDP-mannose mannosyl hydrolase activity
HCLPGIIE_02140	7.86e-281	-	-	-	M	ko:K02005	-	ko00000	HlyD family secretion protein
HCLPGIIE_02141	1.75e-161	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HCLPGIIE_02143	8.38e-98	-	-	-	-	-	-	-	-
HCLPGIIE_02144	0.0	-	-	-	V	-	-	-	ABC-2 type transporter
HCLPGIIE_02147	7.77e-144	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
HCLPGIIE_02151	2.07e-299	-	-	-	MU	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	efflux transmembrane transporter activity
HCLPGIIE_02154	4.36e-200	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Enoyl-CoA hydratase/isomerase
HCLPGIIE_02155	5.24e-257	-	-	-	S	-	-	-	AAA domain, putative AbiEii toxin, Type IV TA system