ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
PHOPOLEM_00001 1.02e-219 parA - - D ko:K03496 - ko00000,ko03036,ko04812 CobQ CobB MinD ParA nucleotide binding domain protein
PHOPOLEM_00002 1.33e-167 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
PHOPOLEM_00003 2.6e-118 jag - - S ko:K06346 - ko00000 Putative single-stranded nucleic acids-binding domain
PHOPOLEM_00004 2.26e-244 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Membrane protein insertase, YidC Oxa1 family
PHOPOLEM_00005 2.68e-19 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
PHOPOLEM_00006 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PHOPOLEM_00007 1.09e-260 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
PHOPOLEM_00008 3.17e-298 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PHOPOLEM_00009 1.01e-115 - - - S - - - Protein of unknown function (DUF721)
PHOPOLEM_00010 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PHOPOLEM_00011 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PHOPOLEM_00012 5.13e-106 - - - S - - - Transmembrane domain of unknown function (DUF3566)
PHOPOLEM_00013 0.0 gdhA 1.4.1.4 - E ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
PHOPOLEM_00014 2.21e-97 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
PHOPOLEM_00018 3.41e-142 - - - S ko:K07043 - ko00000 Protein of unknown function DUF45
PHOPOLEM_00019 2.82e-240 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
PHOPOLEM_00020 5.81e-307 - - - P ko:K03699 - ko00000,ko02042 Transporter associated domain
PHOPOLEM_00021 1.67e-153 cah 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
PHOPOLEM_00022 0.0 ppc 4.1.1.31 - H ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
PHOPOLEM_00023 0.0 - - - S - - - Threonine/Serine exporter, ThrE
PHOPOLEM_00024 0.0 - - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PHOPOLEM_00025 6.48e-263 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
PHOPOLEM_00026 1.49e-64 - - - S - - - Protein of unknown function (DUF3073)
PHOPOLEM_00027 1.1e-82 - - - I - - - Sterol carrier protein
PHOPOLEM_00028 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
PHOPOLEM_00029 8.12e-45 - - - - - - - -
PHOPOLEM_00030 3.84e-189 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Rhomboid family
PHOPOLEM_00031 5.83e-309 - - - L - - - ribosomal rna small subunit methyltransferase
PHOPOLEM_00032 2.28e-90 crgA - - D - - - Involved in cell division
PHOPOLEM_00033 5.3e-181 - - - S - - - Bacterial protein of unknown function (DUF881)
PHOPOLEM_00034 1.12e-265 srtB 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
PHOPOLEM_00035 3.3e-154 trpG 2.6.1.85, 4.1.3.27 - EH ko:K01658,ko:K01664 ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 para-aminobenzoate synthase glutamine amidotransferase component II
PHOPOLEM_00036 0.0 pknB 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 Protein tyrosine kinase
PHOPOLEM_00037 4.29e-227 pknA 2.7.11.1 - T ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 Protein tyrosine kinase
PHOPOLEM_00038 0.0 pbpA - - M ko:K05364 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
PHOPOLEM_00039 0.0 rodA - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
PHOPOLEM_00040 0.0 pstP 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 Sigma factor PP2C-like phosphatases
PHOPOLEM_00041 1.57e-108 fhaB - - T - - - Inner membrane component of T3SS, cytoplasmic domain
PHOPOLEM_00042 2.6e-168 fhaA - - T - - - Protein of unknown function (DUF2662)
PHOPOLEM_00043 0.0 pepX 3.4.14.5 - E ko:K01278 ko04974,map04974 ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 Dipeptidyl peptidase IV (DPP IV) N-terminal region
PHOPOLEM_00044 6.65e-185 - - - T - - - Histidine kinase
PHOPOLEM_00045 4.16e-85 - - - T - - - Histidine kinase
PHOPOLEM_00046 7.71e-146 - - - K - - - helix_turn_helix, Lux Regulon
PHOPOLEM_00047 4.75e-245 pldB 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Serine aminopeptidase, S33
PHOPOLEM_00048 2.14e-213 - - - EG - - - EamA-like transporter family
PHOPOLEM_00049 1.4e-109 - - - S ko:K07118 - ko00000 NAD(P)H-binding
PHOPOLEM_00050 1.76e-57 - - - K - - - HxlR-like helix-turn-helix
PHOPOLEM_00052 0.0 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
PHOPOLEM_00053 0.0 degP - - O ko:K08372 ko02020,map02020 ko00000,ko00001,ko01000,ko01002 Domain present in PSD-95, Dlg, and ZO-1/2.
PHOPOLEM_00054 0.0 - 3.6.3.4, 3.6.3.54 - P ko:K01533,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 E1-E2 ATPase
PHOPOLEM_00055 1.58e-240 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 Asparaginase
PHOPOLEM_00056 0.0 - - - E ko:K11738 - ko00000,ko02000 aromatic amino acid transport protein AroP K03293
PHOPOLEM_00057 0.0 fprA 1.18.1.2, 1.19.1.1 - C ko:K00528 - ko00000,ko01000 Pyridine nucleotide-disulphide oxidoreductase
PHOPOLEM_00058 1.27e-252 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
PHOPOLEM_00060 1.42e-218 - - - EG - - - EamA-like transporter family
PHOPOLEM_00061 0.0 - - - S ko:K01421 - ko00000 YhgE Pip domain protein
PHOPOLEM_00062 0.0 - - - S ko:K01421 - ko00000 YhgE Pip domain protein
PHOPOLEM_00063 2.49e-261 fbaA 4.1.2.13 - G ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-bisphosphate aldolase class-II
PHOPOLEM_00064 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PHOPOLEM_00065 0.0 - - - P ko:K03281 - ko00000 Voltage gated chloride channel
PHOPOLEM_00066 6.22e-194 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PHOPOLEM_00067 4.48e-85 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PHOPOLEM_00068 6.19e-304 - - - U ko:K01997,ko:K11956 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
PHOPOLEM_00069 2.29e-208 livM - - U ko:K01998 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
PHOPOLEM_00070 8.75e-237 - - - E ko:K01995 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid ATP-binding cassette transporter
PHOPOLEM_00071 8.38e-191 livF - - E ko:K01996 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ATPases associated with a variety of cellular activities
PHOPOLEM_00072 8.27e-267 livK - - E ko:K01999 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Receptor family ligand binding region
PHOPOLEM_00073 4.99e-291 livK - - E ko:K01999 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Receptor family ligand binding region
PHOPOLEM_00074 9.41e-257 - - - K ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
PHOPOLEM_00075 2.14e-233 pabC 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 Amino-transferase class IV
PHOPOLEM_00076 2.73e-201 - - - S - - - Protein of unknown function (DUF1445)
PHOPOLEM_00077 7.92e-182 ycsF - - S ko:K07160 - ko00000 LamB/YcsF family
PHOPOLEM_00078 0.0 - - - E - - - Allophanate hydrolase subunit 2
PHOPOLEM_00079 0.0 accBC3 6.3.4.14, 6.4.1.2, 6.4.1.3 - I ko:K11263 ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase C-terminal domain
PHOPOLEM_00080 8.67e-228 - - - S - - - Domain of unknown function (DUF4392)
PHOPOLEM_00081 0.0 gtfA 2.4.1.7 GH13 G ko:K00690 ko00500,map00500 ko00000,ko00001,ko01000 Domain of unknown function (DUF1964)
PHOPOLEM_00082 9.39e-149 - - - S - - - Protein of unknown function, DUF624
PHOPOLEM_00083 0.0 - 2.4.1.4, 3.2.1.1, 3.2.1.20, 5.4.99.16 GH13,GH31 G ko:K01187,ko:K05341,ko:K05343 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha-amylase domain
PHOPOLEM_00084 1.76e-281 - - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
PHOPOLEM_00085 1.27e-203 - - - P ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PHOPOLEM_00086 2.53e-184 - - - P ko:K02026,ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PHOPOLEM_00087 0.0 scrT - - G - - - Transporter major facilitator family protein
PHOPOLEM_00088 0.0 - - - EGP - - - Sugar (and other) transporter
PHOPOLEM_00089 2.65e-259 ilvC 1.1.1.86 - H ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
PHOPOLEM_00090 3.55e-258 ilvC 1.1.1.86 - H ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
PHOPOLEM_00091 0.0 - 3.1.1.53 - E ko:K05970 - ko00000,ko01000 Carbohydrate esterase, sialic acid-specific acetylesterase
PHOPOLEM_00092 5.54e-51 - 3.2.1.25 - G ko:K01192 ko00511,ko04142,map00511,map04142 ko00000,ko00001,ko01000 beta-mannosidase
PHOPOLEM_00093 1.25e-241 - - - K - - - helix_turn _helix lactose operon repressor
PHOPOLEM_00094 4.62e-15 - - - S - - - Protein of unknown function, DUF624
PHOPOLEM_00095 0.0 aroP - - E ko:K03293,ko:K11732 - ko00000,ko02000 aromatic amino acid transport protein AroP K03293
PHOPOLEM_00096 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
PHOPOLEM_00097 3.48e-310 - - - P - - - Sodium/hydrogen exchanger family
PHOPOLEM_00098 1.4e-100 - - - S - - - Psort location Cytoplasmic, score 8.87
PHOPOLEM_00099 1.46e-225 - 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
PHOPOLEM_00100 0.0 - - - M - - - domain protein
PHOPOLEM_00101 3.46e-278 - - - M - - - LPXTG cell wall anchor motif
PHOPOLEM_00102 6.5e-115 - - - S - - - Psort location Cytoplasmic, score 8.87
PHOPOLEM_00103 0.0 - - - E ko:K03293 - ko00000 Amino acid permease
PHOPOLEM_00104 1.79e-214 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
PHOPOLEM_00105 2.91e-166 thiF 2.7.7.73 - H ko:K03148 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 ThiF family
PHOPOLEM_00106 4.87e-37 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 ThiS family
PHOPOLEM_00107 4.63e-259 - - - C - - - Aldo/keto reductase family
PHOPOLEM_00108 3.63e-110 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
PHOPOLEM_00109 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
PHOPOLEM_00110 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter transmembrane region
PHOPOLEM_00111 8.71e-258 - 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
PHOPOLEM_00112 0.0 - - - P ko:K07243 - ko00000,ko02000 Iron permease FTR1 family
PHOPOLEM_00113 7.78e-133 - - - P ko:K07230 - ko00000,ko02000 Fe2+ transport protein
PHOPOLEM_00114 9.35e-293 - - - S - - - Predicted membrane protein (DUF2318)
PHOPOLEM_00115 1.7e-287 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
PHOPOLEM_00117 5.99e-271 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
PHOPOLEM_00118 1.69e-192 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
PHOPOLEM_00119 2.32e-110 - - - S - - - FMN_bind
PHOPOLEM_00120 2.25e-119 - - - K - - - Psort location Cytoplasmic, score 8.87
PHOPOLEM_00121 0.0 - - - S ko:K01421 - ko00000 YhgE Pip domain protein
PHOPOLEM_00122 0.0 - - - S ko:K01421 - ko00000 YhgE Pip domain protein
PHOPOLEM_00123 8.57e-289 - - - S - - - Putative ABC-transporter type IV
PHOPOLEM_00124 2.38e-50 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
PHOPOLEM_00125 2.16e-200 - - - M - - - cell wall binding repeat
PHOPOLEM_00126 1.76e-29 - - - - - - - -
PHOPOLEM_00127 3.07e-102 - - - L - - - Belongs to the 'phage' integrase family
PHOPOLEM_00128 6.29e-27 - - - L ko:K07483 - ko00000 Psort location Cytoplasmic, score 8.87
PHOPOLEM_00129 8.14e-166 - - - L ko:K07483 - ko00000 Integrase core domain
PHOPOLEM_00130 1.46e-44 - - - S - - - Putative ABC-transporter type IV
PHOPOLEM_00133 0.0 kdpA 3.6.3.12 - P ko:K01546 ko02020,map02020 ko00000,ko00001,ko01000 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
PHOPOLEM_00134 0.0 kdpB 3.6.3.12 - P ko:K01547 ko02020,map02020 ko00000,ko00001,ko01000 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
PHOPOLEM_00135 1.36e-89 kdpC 3.6.3.12 - P ko:K01548 ko02020,map02020 ko00000,ko00001,ko01000 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
PHOPOLEM_00136 0.0 kdpD 2.7.13.3 - T ko:K07646 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Osmosensitive K+ channel His kinase sensor domain
PHOPOLEM_00137 3.87e-136 kdpE - - KT ko:K02483,ko:K07667 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
PHOPOLEM_00138 5.23e-45 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
PHOPOLEM_00140 0.0 - - - E ko:K08659 - ko00000,ko01000,ko01002 Peptidase family C69
PHOPOLEM_00141 1.67e-250 - 2.7.8.12 - M ko:K09809 - ko00000,ko01000 Glycosyltransferase like family 2
PHOPOLEM_00143 1.73e-145 icaR - - K - - - Bacterial regulatory proteins, tetR family
PHOPOLEM_00144 9.18e-248 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
PHOPOLEM_00145 1.45e-302 amt - - U ko:K03320 - ko00000,ko02000 Ammonium Transporter Family
PHOPOLEM_00146 2.56e-72 glnB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Nitrogen regulatory protein P-II
PHOPOLEM_00147 0.0 glnD 2.7.7.59 - O ko:K00990 ko02020,map02020 ko00000,ko00001,ko01000 Nucleotidyltransferase domain
PHOPOLEM_00148 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
PHOPOLEM_00149 0.0 murE - - M - - - Domain of unknown function (DUF1727)
PHOPOLEM_00150 1.14e-175 cobQ2 - - S ko:K07009 - ko00000 CobB/CobQ-like glutamine amidotransferase domain
PHOPOLEM_00151 4.06e-42 - - - S - - - granule-associated protein
PHOPOLEM_00152 0.0 - - - S ko:K03688 - ko00000 ABC1 family
PHOPOLEM_00153 4.58e-246 - - - K ko:K02529 - ko00000,ko03000 Periplasmic binding protein domain
PHOPOLEM_00154 2.15e-315 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
PHOPOLEM_00156 5.95e-214 - - - P ko:K02025,ko:K10189 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PHOPOLEM_00157 3.39e-187 - - - G ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PHOPOLEM_00158 0.0 - 3.2.1.185 GH127 S ko:K09955,ko:K18205 - ko00000,ko01000 Beta-L-arabinofuranosidase, GH127
PHOPOLEM_00159 0.0 - 3.2.1.187 GH121 DG ko:K18206 - ko00000,ko01000 Bacterial Ig-like domain (group 4)
PHOPOLEM_00160 0.0 - - - G - - - Bacterial Ig-like domain (group 4)
PHOPOLEM_00161 0.0 - - - S - - - Psort location CytoplasmicMembrane, score 9.99
PHOPOLEM_00162 4.62e-309 - - - V - - - ABC transporter permease
PHOPOLEM_00163 3.41e-237 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
PHOPOLEM_00164 4.51e-192 - - - T ko:K06950 - ko00000 HD domain
PHOPOLEM_00165 1.12e-212 - - - S - - - Glutamine amidotransferase domain
PHOPOLEM_00166 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
PHOPOLEM_00167 8.42e-236 tatD - - L ko:K03424 - ko00000,ko01000 TatD related DNase
PHOPOLEM_00168 0.0 - - - G - - - Alpha-L-arabinofuranosidase C-terminus
PHOPOLEM_00169 2.66e-30 - - - G - - - alpha-galactosidase
PHOPOLEM_00170 3.47e-286 - - - K - - - helix_turn _helix lactose operon repressor
PHOPOLEM_00171 0.0 - 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.87
PHOPOLEM_00172 6.8e-162 - - - - - - - -
PHOPOLEM_00173 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter
PHOPOLEM_00174 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter
PHOPOLEM_00175 4.42e-273 - - - I - - - Hydrolase, alpha beta domain protein
PHOPOLEM_00177 1.92e-198 - - - I - - - alpha/beta hydrolase fold
PHOPOLEM_00178 3.31e-307 - - - M - - - Protein of unknown function (DUF2961)
PHOPOLEM_00179 1.51e-120 - - - T - - - Diguanylate cyclase, GGDEF domain
PHOPOLEM_00180 6.89e-240 - - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
PHOPOLEM_00181 3.71e-302 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Amidohydrolase family
PHOPOLEM_00182 9.06e-191 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
PHOPOLEM_00183 0.0 - - - G - - - Glycosyl hydrolase family 20, domain 2
PHOPOLEM_00184 6.71e-213 - 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
PHOPOLEM_00185 5.8e-33 - - - G ko:K02026 - ko00000,ko00002,ko02000 ABC transporter permease
PHOPOLEM_00186 0.0 - 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
PHOPOLEM_00187 2.05e-232 - - - K - - - helix_turn _helix lactose operon repressor
PHOPOLEM_00188 0.0 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
PHOPOLEM_00189 3.56e-154 - - - G ko:K02026 - ko00000,ko00002,ko02000 ABC transporter permease
PHOPOLEM_00190 5.79e-269 - - - GK - - - ROK family
PHOPOLEM_00191 0.0 gph - - G ko:K16209 - ko00000,ko02000 Psort location CytoplasmicMembrane, score 10.00
PHOPOLEM_00192 0.0 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.87
PHOPOLEM_00193 1.99e-175 - 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4-amino-5-aminomethyl-2-methylpyrimidine to 4-amino- 5-hydroxymethyl-2-methylpyrimidine (HMP)
PHOPOLEM_00195 0.0 lacZ3 - - G - - - Belongs to the glycosyl hydrolase 2 family
PHOPOLEM_00196 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PHOPOLEM_00197 1.32e-137 - - - - - - - -
PHOPOLEM_00198 2.6e-240 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PHOPOLEM_00199 1.89e-22 - 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Glycosyl hydrolase family 26
PHOPOLEM_00200 3.68e-160 dedA1 - - S ko:K03975 - ko00000 SNARE associated Golgi protein
PHOPOLEM_00202 1.69e-166 - - - S - - - HAD hydrolase, family IA, variant 3
PHOPOLEM_00203 6.08e-63 - - - - - - - -
PHOPOLEM_00204 1.61e-146 hspR - - K ko:K13640 - ko00000,ko03000 transcriptional regulator, MerR family
PHOPOLEM_00205 7.5e-238 dnaJ - - O ko:K03686,ko:K05516 - ko00000,ko03029,ko03036,ko03110 DnaJ molecular chaperone homology domain
PHOPOLEM_00206 3.85e-105 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PHOPOLEM_00207 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
PHOPOLEM_00208 5.66e-187 - - - S - - - Mitochondrial biogenesis AIM24
PHOPOLEM_00209 1.74e-152 strK 3.1.3.1, 3.1.3.39 - P ko:K01077,ko:K04342 ko00521,ko00730,ko00790,ko01100,ko01130,ko02020,map00521,map00730,map00790,map01100,map01130,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Alkaline phosphatase homologues
PHOPOLEM_00210 1.15e-180 - - - S ko:K07090 - ko00000 membrane transporter protein
PHOPOLEM_00211 2.3e-199 - 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
PHOPOLEM_00212 5.39e-245 - - - M - - - Cna protein B-type domain
PHOPOLEM_00213 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
PHOPOLEM_00214 0.0 - - - M - - - cell wall anchor domain protein
PHOPOLEM_00215 4.96e-247 - - - K - - - Psort location Cytoplasmic, score
PHOPOLEM_00216 1.34e-184 traX - - S - - - TraX protein
PHOPOLEM_00217 6.12e-186 - - - S ko:K07025 - ko00000 HAD-hyrolase-like
PHOPOLEM_00218 0.0 apuB 3.2.1.41, 3.2.1.68 CBM48,GH13 G ko:K01200,ko:K01214 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 13 family
PHOPOLEM_00219 1.52e-208 malG - - G ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PHOPOLEM_00220 0.0 malC - - G ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PHOPOLEM_00221 1.16e-302 malE - - G ko:K15770 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
PHOPOLEM_00222 0.0 malL 2.4.1.4, 3.2.1.1, 3.2.1.20, 5.4.99.16 GH13,GH31 G ko:K01187,ko:K05341,ko:K05343 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha-amylase domain
PHOPOLEM_00223 0.0 malQ 2.4.1.25 GH77 G ko:K00705 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 4-alpha-glucanotransferase
PHOPOLEM_00224 1.21e-137 - - - S - - - Protein of unknown function, DUF624
PHOPOLEM_00225 5.24e-195 - - - G ko:K02026,ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
PHOPOLEM_00226 2.23e-198 msmF - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PHOPOLEM_00227 5.68e-234 - - - K - - - Psort location Cytoplasmic, score
PHOPOLEM_00228 2.16e-241 - - - K - - - Periplasmic binding protein-like domain
PHOPOLEM_00229 0.0 amyE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
PHOPOLEM_00230 0.0 - 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha-amylase domain
PHOPOLEM_00231 0.0 amyE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
PHOPOLEM_00232 4.88e-177 gpm2 3.1.3.73 - G ko:K02226 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Phosphoglycerate mutase family
PHOPOLEM_00233 4.34e-82 - - - S - - - Protein of unknown function (DUF4235)
PHOPOLEM_00234 4.65e-183 nfrA - - C - - - Nitroreductase family
PHOPOLEM_00235 1.66e-59 - - - - - - - -
PHOPOLEM_00236 4.73e-109 - - - K - - - Cro/C1-type HTH DNA-binding domain
PHOPOLEM_00237 0.0 pacL2 3.6.3.8 - P ko:K01537 - ko00000,ko01000 Cation transporter/ATPase, N-terminus
PHOPOLEM_00238 0.0 - - - L - - - AAA domain
PHOPOLEM_00239 0.0 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.87
PHOPOLEM_00240 3.34e-193 - - - S - - - Short repeat of unknown function (DUF308)
PHOPOLEM_00241 1.94e-66 - - - S - - - Antitoxin component of a toxin-antitoxin (TA) module
PHOPOLEM_00242 8.36e-72 - - - DJ ko:K06218 - ko00000,ko02048 Addiction module toxin, RelE StbE family
PHOPOLEM_00243 6.49e-19 - - - S - - - Psort location Extracellular, score 8.82
PHOPOLEM_00244 1.36e-294 - - - EGP - - - Transmembrane secretion effector
PHOPOLEM_00245 4.23e-223 rlmB 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PHOPOLEM_00246 0.0 - - - KLT - - - Domain of unknown function (DUF4032)
PHOPOLEM_00247 1.26e-268 ugpC - - E ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
PHOPOLEM_00248 1.45e-167 - - - K - - - LytTr DNA-binding domain
PHOPOLEM_00249 1.49e-315 - - - T - - - GHKL domain
PHOPOLEM_00250 1.45e-274 - - - P ko:K03281 - ko00000 Voltage gated chloride channel
PHOPOLEM_00251 4.14e-256 - - - C - - - Acetamidase/Formamidase family
PHOPOLEM_00252 4.62e-108 - - - K ko:K05799 - ko00000,ko03000 FCD
PHOPOLEM_00253 8.63e-181 - 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
PHOPOLEM_00254 7.85e-152 - - - U ko:K02029 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PHOPOLEM_00255 6.08e-194 - - - ET ko:K02030 - ko00000,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
PHOPOLEM_00256 8.62e-274 - 2.6.1.1 - E ko:K00812,ko:K10907 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase class I and II
PHOPOLEM_00257 7.69e-127 - - - S - - - GtrA-like protein
PHOPOLEM_00258 0.0 - 3.2.1.21 GH3 G ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Glycosyl hydrolase family 3 N-terminal domain protein
PHOPOLEM_00259 8.25e-155 - 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Psort location CytoplasmicMembrane, score
PHOPOLEM_00260 1.48e-105 ypeA 2.3.1.1 - K ko:K22477 ko00220,ko01210,ko01230,map00220,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Psort location Cytoplasmic, score 8.87
PHOPOLEM_00261 1.84e-147 vex - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
PHOPOLEM_00262 7.08e-273 - - - V ko:K02004 - ko00000,ko00002,ko02000 Efflux ABC transporter, permease protein
PHOPOLEM_00263 1.47e-200 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
PHOPOLEM_00264 3.79e-61 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
PHOPOLEM_00265 1.05e-37 gph - - G ko:K16209 - ko00000,ko02000 Psort location CytoplasmicMembrane, score 10.00
PHOPOLEM_00266 2.21e-53 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative ATP-dependent DNA helicase recG C-terminal
PHOPOLEM_00267 2.7e-296 - - - EGP ko:K08177 - ko00000,ko02000 Major Facilitator Superfamily
PHOPOLEM_00268 0.0 - 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Thioredoxin domain
PHOPOLEM_00269 1.22e-138 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 C-terminal domain of 1-Cys peroxiredoxin
PHOPOLEM_00270 0.0 - 3.2.1.21 GH3 G ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Fibronectin type III-like domain
PHOPOLEM_00271 0.0 - - - KLT - - - Protein tyrosine kinase
PHOPOLEM_00272 1.62e-213 - - - O - - - Thioredoxin
PHOPOLEM_00274 1.25e-175 rpfB - - S ko:K21688 - ko00000 G5
PHOPOLEM_00275 7.61e-48 rpfB - - S ko:K21688 - ko00000 G5
PHOPOLEM_00276 1.73e-219 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
PHOPOLEM_00277 4.39e-214 ispE 2.7.1.148 - F ko:K00919 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
PHOPOLEM_00278 8.42e-142 - - - S - - - LytR cell envelope-related transcriptional attenuator
PHOPOLEM_00279 1.76e-196 pcnA 2.7.7.19, 2.7.7.72 - J ko:K00970,ko:K00974 ko03013,ko03018,map03013,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 Probable RNA and SrmB- binding site of polymerase A
PHOPOLEM_00280 2.21e-156 mutT4 - - L - - - Belongs to the Nudix hydrolase family
PHOPOLEM_00281 0.0 - - - M - - - Conserved repeat domain
PHOPOLEM_00282 0.0 mviN - - KLT ko:K03980 - ko00000,ko01011,ko02000 MviN-like protein
PHOPOLEM_00283 0.0 - - - KLT ko:K03980 - ko00000,ko01011,ko02000 MviN-like protein
PHOPOLEM_00284 1.2e-152 - - - S - - - 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
PHOPOLEM_00286 1.6e-19 - - - S - - - Psort location Extracellular, score 8.82
PHOPOLEM_00287 2.15e-92 - - - K - - - FCD
PHOPOLEM_00288 1.69e-154 - - - EGP - - - Major facilitator Superfamily
PHOPOLEM_00289 0.0 - - - IQ ko:K06978 - ko00000 Peptidase S15
PHOPOLEM_00290 7.99e-211 - - - E - - - Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
PHOPOLEM_00291 1.36e-147 - - - U ko:K02053,ko:K11070,ko:K11074 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PHOPOLEM_00292 2.26e-164 - - - U ko:K02054,ko:K11071 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PHOPOLEM_00293 5.94e-204 potD - - E ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Required for the activity of the bacterial periplasmic transport system of putrescine
PHOPOLEM_00294 2.07e-185 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
PHOPOLEM_00295 3.22e-135 - - - EH - - - D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
PHOPOLEM_00296 6.95e-231 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
PHOPOLEM_00297 1.67e-201 parB - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
PHOPOLEM_00298 3.93e-34 - - - - - - - -
PHOPOLEM_00299 2.99e-144 dcd 3.5.4.13 - F ko:K01494 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dCTP deaminase family
PHOPOLEM_00300 3.86e-195 - - - S ko:K06999 - ko00000 Phospholipase/Carboxylesterase
PHOPOLEM_00301 0.0 nhaP - - P ko:K03316 - ko00000 Sodium/hydrogen exchanger family
PHOPOLEM_00302 2.32e-100 tadA 3.5.4.1, 3.5.4.33 - FJ ko:K01485,ko:K11991 ko00240,ko00330,ko01100,map00240,map00330,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
PHOPOLEM_00303 0.0 - 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Glycosyl hydrolase family 36 N-terminal domain
PHOPOLEM_00304 5.18e-295 - - - GK - - - ROK family
PHOPOLEM_00305 6.1e-313 - - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
PHOPOLEM_00306 2.9e-203 - - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PHOPOLEM_00307 4.88e-198 - - - G ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PHOPOLEM_00308 0.0 - 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
PHOPOLEM_00309 1.76e-296 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Pyridoxal-phosphate dependent enzyme
PHOPOLEM_00310 7.48e-185 cobB2 - - K ko:K12410 - ko00000,ko01000 Sir2 family
PHOPOLEM_00312 1.88e-219 - - - I - - - alpha/beta hydrolase fold
PHOPOLEM_00313 5.69e-84 - - - L - - - Transposase and inactivated derivatives IS30 family
PHOPOLEM_00315 2.72e-140 - - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PHOPOLEM_00316 1.09e-261 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Glycerophosphoryl diester phosphodiesterase family
PHOPOLEM_00317 1.64e-151 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PHOPOLEM_00318 2.32e-133 - - - - - - - -
PHOPOLEM_00319 1.08e-287 mutT 3.6.1.55 - LT ko:K03574 - ko00000,ko01000,ko03400 Phosphoglycerate mutase family
PHOPOLEM_00320 0.0 ppk 2.7.4.1 - P ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
PHOPOLEM_00321 1.44e-180 - - - D - - - bacterial-type flagellum organization
PHOPOLEM_00322 5.94e-237 cpaF - - U ko:K02283 - ko00000,ko02035,ko02044 Type II IV secretion system protein
PHOPOLEM_00323 3.6e-172 - - - U ko:K12510 - ko00000,ko02044 Type ii secretion system
PHOPOLEM_00324 1.7e-118 - - - NU - - - Type II secretion system (T2SS), protein F
PHOPOLEM_00325 3.15e-56 - - - S - - - Protein of unknown function (DUF4244)
PHOPOLEM_00326 1.8e-79 - - - U - - - TadE-like protein
PHOPOLEM_00327 7.92e-72 - - - S - - - TIGRFAM helicase secretion neighborhood TadE-like protein
PHOPOLEM_00328 9.99e-273 - 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Diacylglycerol kinase catalytic domain protein
PHOPOLEM_00329 6.51e-249 - - - S - - - Psort location CytoplasmicMembrane, score
PHOPOLEM_00330 1.57e-128 - - - K - - - Bacterial regulatory proteins, tetR family
PHOPOLEM_00331 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III subunit gamma tau
PHOPOLEM_00332 6.41e-136 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PHOPOLEM_00333 7.1e-175 ask 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Amino acid kinase family
PHOPOLEM_00334 1.17e-125 ask 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 ACT domain
PHOPOLEM_00335 5.73e-264 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PHOPOLEM_00336 3.43e-88 - - - - - - - -
PHOPOLEM_00337 1.37e-39 - - - - - - - -
PHOPOLEM_00338 8.04e-56 - - - K - - - helix_turn_helix, Lux Regulon
PHOPOLEM_00339 5.88e-15 - - - T - - - Histidine kinase
PHOPOLEM_00340 8.81e-148 - - - - - - - -
PHOPOLEM_00341 0.0 - - - S - - - Calcineurin-like phosphoesterase
PHOPOLEM_00342 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PHOPOLEM_00343 0.0 - 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 C-terminal of Glycosyl hydrolases family 43
PHOPOLEM_00344 0.0 - 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 C-terminal of Glycosyl hydrolases family 43
PHOPOLEM_00345 0.0 - - - G - - - Glycosyl hydrolases family 43
PHOPOLEM_00346 5.38e-250 - - - K - - - helix_turn _helix lactose operon repressor
PHOPOLEM_00347 3.82e-258 - - - G - - - Glycosyl hydrolases family 43
PHOPOLEM_00348 0.0 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
PHOPOLEM_00349 7.58e-217 - - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PHOPOLEM_00350 2.14e-205 - - - U ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PHOPOLEM_00351 0.0 - - - S ko:K09955 - ko00000 Beta-L-arabinofuranosidase, GH127
PHOPOLEM_00352 0.0 pbp5 - - M - - - Transglycosylase
PHOPOLEM_00353 1.1e-276 ino1 5.5.1.4 - I ko:K01858 ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130 ko00000,ko00001,ko01000 Myo-inositol-1-phosphate synthase
PHOPOLEM_00354 2.2e-298 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
PHOPOLEM_00355 7.47e-244 - - - I - - - PAP2 superfamily
PHOPOLEM_00356 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PHOPOLEM_00357 8.68e-150 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PHOPOLEM_00358 2.39e-257 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
PHOPOLEM_00359 1.73e-61 - 2.7.1.194 - G ko:K02821 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PHOPOLEM_00360 1.12e-48 - 2.7.1.194 - G ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
PHOPOLEM_00361 3.51e-272 - - - S ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
PHOPOLEM_00362 1.67e-113 - - - K ko:K03710 - ko00000,ko03000 UTRA domain
PHOPOLEM_00363 1.02e-236 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
PHOPOLEM_00364 6.22e-52 hpr - - G ko:K11189 - ko00000,ko02000 PTS HPr component phosphorylation site
PHOPOLEM_00365 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PHOPOLEM_00366 5.02e-139 - - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
PHOPOLEM_00367 0.0 pepD - - E ko:K08659 - ko00000,ko01000,ko01002 Peptidase family C69
PHOPOLEM_00368 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Formate-tetrahydrofolate ligase
PHOPOLEM_00369 5.29e-80 - - - S - - - Macrophage migration inhibitory factor (MIF)
PHOPOLEM_00370 1.29e-124 - - - S - - - GtrA-like protein
PHOPOLEM_00371 0.0 - - - EGP - - - Major Facilitator Superfamily
PHOPOLEM_00372 1.24e-158 - - - G - - - Phosphoglycerate mutase family
PHOPOLEM_00373 1.86e-242 - - - - - - - -
PHOPOLEM_00374 4.65e-189 - - - S - - - Protein of unknown function (DUF805)
PHOPOLEM_00375 0.0 gltX 6.1.1.17 - J ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PHOPOLEM_00378 0.0 - - - S - - - Calcineurin-like phosphoesterase
PHOPOLEM_00379 1.9e-180 ltbR - - K - - - Transcriptional regulator, IclR family, C-terminal domain protein
PHOPOLEM_00380 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PHOPOLEM_00381 2.1e-169 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PHOPOLEM_00382 6.6e-259 pyr 1.3.98.1 - F ko:K00226 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Dihydroorotate dehydrogenase
PHOPOLEM_00383 0.0 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PHOPOLEM_00384 2.46e-225 plsC2 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Phosphate acyltransferases
PHOPOLEM_00385 2.16e-227 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
PHOPOLEM_00386 2.32e-280 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
PHOPOLEM_00387 1.14e-277 - - - P ko:K02055 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
PHOPOLEM_00388 1.13e-203 - - - U ko:K02054 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PHOPOLEM_00389 2.76e-189 - - - U ko:K02053 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PHOPOLEM_00390 1.38e-272 - - - E ko:K02052 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
PHOPOLEM_00391 1.76e-223 - - - S - - - CAAX protease self-immunity
PHOPOLEM_00392 1.38e-177 - - - M - - - Mechanosensitive ion channel
PHOPOLEM_00393 3.53e-294 - - - S - - - Psort location Cytoplasmic, score 8.87
PHOPOLEM_00394 2.18e-289 - - - S - - - Psort location Cytoplasmic, score 8.87
PHOPOLEM_00395 2.32e-161 - - - K - - - Bacterial regulatory proteins, tetR family
PHOPOLEM_00396 9.29e-293 - 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Psort location Cytoplasmic, score 8.87
PHOPOLEM_00397 1.03e-103 gntK 2.7.1.12 - F ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Shikimate kinase
PHOPOLEM_00398 1.01e-165 gntR - - K - - - FCD
PHOPOLEM_00399 2.39e-294 - - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 Vacuole effluxer Atg22 like
PHOPOLEM_00400 1.82e-41 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal L28 family
PHOPOLEM_00401 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 helicase superfamily c-terminal domain
PHOPOLEM_00402 2.94e-134 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Conserved hypothetical protein 95
PHOPOLEM_00403 2.2e-193 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
PHOPOLEM_00404 2.11e-137 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PHOPOLEM_00405 5.05e-47 - - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
PHOPOLEM_00406 7.94e-83 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
PHOPOLEM_00407 1.23e-232 - - - S - - - Endonuclease/Exonuclease/phosphatase family
PHOPOLEM_00408 0.0 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PHOPOLEM_00409 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
PHOPOLEM_00410 9.8e-195 - 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Peptidase C26
PHOPOLEM_00411 0.0 yjjK - - S ko:K15738 - ko00000,ko02000 ABC transporter
PHOPOLEM_00412 1.62e-123 - - - - - - - -
PHOPOLEM_00413 5.88e-315 - - - S ko:K07133 - ko00000 Domain of unknown function (DUF4143)
PHOPOLEM_00414 1.54e-118 ilvN 2.2.1.6 - E ko:K01653 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 ACT domain
PHOPOLEM_00415 0.0 ilvB 2.2.1.6 - H ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Thiamine pyrophosphate enzyme, central domain
PHOPOLEM_00416 8.48e-178 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
PHOPOLEM_00417 8.1e-36 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
PHOPOLEM_00418 1.75e-142 - - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
PHOPOLEM_00419 5.15e-172 - - - - - - - -
PHOPOLEM_00420 6.03e-114 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PHOPOLEM_00421 1.02e-76 - - - S - - - Protein of unknown function (DUF3039)
PHOPOLEM_00422 1.14e-247 - - - C ko:K19265 - ko00000,ko01000 Aldo/keto reductase family
PHOPOLEM_00423 2.47e-101 - - - K - - - MerR, DNA binding
PHOPOLEM_00424 1.02e-155 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PHOPOLEM_00425 2.31e-180 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
PHOPOLEM_00426 0.0 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PHOPOLEM_00427 6.75e-306 - - - V ko:K12554 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Psort location Cytoplasmic, score 8.87
PHOPOLEM_00428 1.15e-298 - - - V ko:K12554 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Psort location Cytoplasmic, score 8.87
PHOPOLEM_00431 7.15e-232 - - - S ko:K07088 - ko00000 Auxin Efflux Carrier
PHOPOLEM_00432 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
PHOPOLEM_00433 3.37e-79 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
PHOPOLEM_00434 2.83e-158 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
PHOPOLEM_00435 2.21e-176 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PHOPOLEM_00436 1.13e-165 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
PHOPOLEM_00437 0.0 - - - V - - - Efflux ABC transporter, permease protein
PHOPOLEM_00438 3.73e-212 - - - S ko:K07088 - ko00000 Transporter, auxin efflux carrier (AEC) family protein
PHOPOLEM_00439 6.81e-293 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Peptidase dimerisation domain
PHOPOLEM_00440 0.0 rne 3.1.26.12 - J ko:K08300,ko:K08301 ko03018,map03018 ko00000,ko00001,ko00002,ko01000,ko03009,ko03019 Ribonuclease E/G family
PHOPOLEM_00441 1.19e-61 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
PHOPOLEM_00442 3.53e-52 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal L27 protein
PHOPOLEM_00443 0.0 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PHOPOLEM_00444 3.06e-261 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PHOPOLEM_00445 6.66e-296 aspC 2.6.1.1, 2.6.1.2, 2.6.1.66 - E ko:K00812,ko:K08969,ko:K14260 ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 DegT/DnrJ/EryC1/StrS aminotransferase family
PHOPOLEM_00447 3.48e-44 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
PHOPOLEM_00448 3.77e-176 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
PHOPOLEM_00449 5.21e-95 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PHOPOLEM_00450 1.18e-157 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
PHOPOLEM_00451 4.85e-185 - - - QT - - - PucR C-terminal helix-turn-helix domain
PHOPOLEM_00452 0.0 - - - - - - - -
PHOPOLEM_00453 7.24e-206 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Biotin/lipoate A/B protein ligase family
PHOPOLEM_00454 3.99e-116 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
PHOPOLEM_00455 0.0 accC 6.3.4.14, 6.4.1.2, 6.4.1.3 - I ko:K11263 ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase L chain, ATP binding domain protein
PHOPOLEM_00456 0.0 pccB - - I - - - Carboxyl transferase domain
PHOPOLEM_00457 0.0 fas - - I ko:K11533 ko00061,ko01100,ko01212,ko04931,map00061,map01100,map01212,map04931 ko00000,ko00001,ko00002,ko01000,ko01004 Beta-ketoacyl synthase, C-terminal domain
PHOPOLEM_00459 1.77e-107 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
PHOPOLEM_00460 0.0 ams 2.4.1.4 GH13 G ko:K05341 ko00500,map00500 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain
PHOPOLEM_00462 6.58e-152 - - - - - - - -
PHOPOLEM_00463 2.04e-56 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PHOPOLEM_00464 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
PHOPOLEM_00465 8.51e-118 lemA - - S ko:K03744 - ko00000 LemA family
PHOPOLEM_00466 0.0 - - - S - - - Predicted membrane protein (DUF2207)
PHOPOLEM_00467 1.53e-217 - - - C - - - Oxidoreductase, aldo keto reductase family protein
PHOPOLEM_00468 0.0 - - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase family U32 C-terminal domain
PHOPOLEM_00469 2.31e-234 yfiH - - Q ko:K05810 - ko00000,ko01000 Multi-copper polyphenol oxidoreductase laccase
PHOPOLEM_00470 6.18e-184 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60 - I ko:K00991,ko:K21681 ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
PHOPOLEM_00471 8.36e-162 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
PHOPOLEM_00472 7.66e-147 - - - D - - - nuclear chromosome segregation
PHOPOLEM_00473 0.0 pepC2 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
PHOPOLEM_00474 2.1e-268 aroG 2.5.1.54 - E ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 ko00000,ko00001,ko00002,ko01000 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PHOPOLEM_00475 1.44e-281 aroG 2.5.1.54 - E ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 ko00000,ko00001,ko00002,ko01000 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PHOPOLEM_00476 1.22e-157 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PHOPOLEM_00477 1.68e-279 phoR 2.7.13.3 - T ko:K07636,ko:K07768 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 His Kinase A (phosphoacceptor) domain
PHOPOLEM_00478 2.31e-166 regX3 - - KT ko:K07776 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
PHOPOLEM_00479 5.23e-257 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import
PHOPOLEM_00480 2.6e-209 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
PHOPOLEM_00481 1.92e-218 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
PHOPOLEM_00482 6.41e-190 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PHOPOLEM_00483 4.99e-181 - - - P ko:K02077 - ko00000,ko00002,ko02000 Zinc-uptake complex component A periplasmic
PHOPOLEM_00484 9.45e-315 - - - S ko:K06901 - ko00000,ko02000 Permease family
PHOPOLEM_00485 5.91e-114 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PHOPOLEM_00486 5.66e-69 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
PHOPOLEM_00487 6.19e-231 - - - T - - - Forkhead associated domain
PHOPOLEM_00488 0.0 - - - L - - - Superfamily I DNA and RNA helicases and helicase subunits
PHOPOLEM_00489 2.9e-49 - - - - - - - -
PHOPOLEM_00490 6.42e-118 - - - NO - - - SAF
PHOPOLEM_00491 1.14e-40 - - - S - - - Putative regulatory protein
PHOPOLEM_00492 2.49e-129 ygfA 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 5-formyltetrahydrofolate cyclo-ligase family
PHOPOLEM_00493 3.82e-156 rimJ 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
PHOPOLEM_00494 4.21e-215 - - - - - - - -
PHOPOLEM_00495 3.49e-63 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PHOPOLEM_00499 7.79e-35 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L33
PHOPOLEM_00500 2.74e-266 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
PHOPOLEM_00501 0.0 - - - E ko:K03294 - ko00000 aromatic amino acid transport protein AroP K03293
PHOPOLEM_00502 2.61e-78 fdxA - - C ko:K05524 - ko00000 4Fe-4S binding domain
PHOPOLEM_00503 2.78e-272 dapC - - E - - - Aminotransferase class I and II
PHOPOLEM_00504 0.0 - - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
PHOPOLEM_00505 1.39e-231 - - - EP ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PHOPOLEM_00506 2.8e-180 - - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PHOPOLEM_00507 8.75e-200 - - - EP ko:K02031,ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Oligopeptide/dipeptide transporter, C-terminal region
PHOPOLEM_00508 1.82e-195 - - - E ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter
PHOPOLEM_00509 0.0 - 3.2.1.37 GH43 G ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
PHOPOLEM_00510 0.0 - - - G - - - Psort location Cytoplasmic, score 8.87
PHOPOLEM_00511 1.13e-298 - 3.2.1.156 GH8 G ko:K15531 - ko00000,ko01000 CBM9 module, glycoside hydrolase family 8 protein and carbohydrate esterase family 4 protein K01238
PHOPOLEM_00512 0.0 - - - G - - - candidate polyfunctional acetylxylan esterase b-xylosidase A-L-arabinofuranosidase, CBM9 module, glycoside hydrolase family 43 protein and carbohydrate esterase family 6 protein K01238
PHOPOLEM_00513 0.0 - - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
PHOPOLEM_00515 1.07e-283 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PHOPOLEM_00516 0.0 - - - M ko:K07282 - ko00000 Bacterial capsule synthesis protein PGA_cap
PHOPOLEM_00517 5.49e-237 pdxB - - EH - - - Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PHOPOLEM_00518 2.32e-146 yigZ - - S - - - Uncharacterized protein family UPF0029
PHOPOLEM_00519 1.05e-158 - - - - - - - -
PHOPOLEM_00520 0.0 malQ 2.4.1.25 GH77 G ko:K00705 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 4-alpha-glucanotransferase
PHOPOLEM_00521 2.26e-104 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PHOPOLEM_00522 1.21e-99 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
PHOPOLEM_00523 0.0 glgX 3.2.1.196, 3.2.1.68 CBM48,GH13 G ko:K01214,ko:K02438 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 13 family
PHOPOLEM_00524 2.55e-100 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PHOPOLEM_00525 2.25e-272 - - - GK - - - transcriptional repressor of nag (N-acetylglucosamine) operon K02565
PHOPOLEM_00526 3.52e-304 csbX - - EGP - - - Major Facilitator Superfamily
PHOPOLEM_00527 2.11e-250 - 1.1.1.9 - C ko:K05351 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Zinc-binding dehydrogenase
PHOPOLEM_00528 1.39e-232 - - - K - - - helix_turn_helix, arabinose operon control protein
PHOPOLEM_00529 0.0 adhE 1.1.1.1, 1.2.1.10, 1.2.1.81 - C ko:K04072,ko:K15515 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
PHOPOLEM_00530 5.42e-67 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
PHOPOLEM_00531 1.64e-151 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PHOPOLEM_00532 3.02e-151 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
PHOPOLEM_00533 8.86e-62 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
PHOPOLEM_00534 2.71e-195 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PHOPOLEM_00535 3.44e-63 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PHOPOLEM_00536 5.42e-75 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PHOPOLEM_00537 2.74e-147 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PHOPOLEM_00538 3.85e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PHOPOLEM_00539 1.37e-50 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
PHOPOLEM_00540 5.52e-55 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PHOPOLEM_00541 2.55e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PHOPOLEM_00542 1.81e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PHOPOLEM_00543 1.6e-133 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PHOPOLEM_00544 4.1e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PHOPOLEM_00545 3.93e-90 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PHOPOLEM_00546 5.66e-124 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PHOPOLEM_00547 1.86e-77 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PHOPOLEM_00548 1.47e-129 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PHOPOLEM_00549 1.24e-35 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30p/L7e
PHOPOLEM_00550 5.12e-96 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
PHOPOLEM_00551 7.19e-315 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
PHOPOLEM_00552 1.05e-127 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
PHOPOLEM_00553 6.91e-45 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PHOPOLEM_00554 1.47e-20 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
PHOPOLEM_00555 6.96e-83 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PHOPOLEM_00556 1.48e-85 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PHOPOLEM_00557 6.43e-238 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PHOPOLEM_00558 7.02e-87 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
PHOPOLEM_00559 8.81e-240 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
PHOPOLEM_00560 0.0 gcs2 - - S ko:K06048 - ko00000,ko01000 A circularly permuted ATPgrasp
PHOPOLEM_00561 5.62e-183 - - - E - - - Transglutaminase/protease-like homologues
PHOPOLEM_00563 8.49e-109 - - - - - - - -
PHOPOLEM_00564 4.21e-243 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
PHOPOLEM_00565 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PHOPOLEM_00566 1.9e-98 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PHOPOLEM_00567 2.03e-240 truB 5.4.99.25 - J ko:K03177 - ko00000,ko01000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PHOPOLEM_00568 2.39e-276 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 riboflavin kinase
PHOPOLEM_00569 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PHOPOLEM_00570 2.31e-140 - - - - - - - -
PHOPOLEM_00571 5.05e-07 - - - S - - - Mitochondrial domain of unknown function (DUF1713)
PHOPOLEM_00572 3.43e-163 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
PHOPOLEM_00573 2.98e-276 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PHOPOLEM_00574 0.0 - - - T - - - GHKL domain
PHOPOLEM_00575 4.18e-195 - - - T - - - LytTr DNA-binding domain
PHOPOLEM_00576 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
PHOPOLEM_00577 0.0 ptsG - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system, glucose-specific IIABC component
PHOPOLEM_00578 3.44e-204 arbG - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
PHOPOLEM_00579 2.42e-263 - - - I - - - Diacylglycerol kinase catalytic domain
PHOPOLEM_00580 2.97e-305 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PHOPOLEM_00582 5.6e-238 - - - O - - - ADP-ribosylglycohydrolase
PHOPOLEM_00583 1.86e-242 - - - G - - - pfkB family carbohydrate kinase
PHOPOLEM_00584 0.0 - - - U ko:K03457 - ko00000 Permease for cytosine/purines, uracil, thiamine, allantoin
PHOPOLEM_00585 2.38e-133 - - - Q - - - Isochorismatase family
PHOPOLEM_00586 8.88e-273 - - - S - - - Choline/ethanolamine kinase
PHOPOLEM_00587 0.0 - - - E ko:K16238 - ko00000,ko02000 Amino acid permease
PHOPOLEM_00588 0.0 - - - H - - - Aminotransferase class-III
PHOPOLEM_00589 1.18e-181 - - - K ko:K03489,ko:K03710 - ko00000,ko03000 UTRA
PHOPOLEM_00590 2.39e-156 tcsR3 - - K - - - helix_turn_helix, Lux Regulon
PHOPOLEM_00591 0.0 tcsS3 - - KT - - - PspC domain
PHOPOLEM_00592 5.43e-197 pspC - - KT - - - PspC domain
PHOPOLEM_00593 9.11e-120 - - - - - - - -
PHOPOLEM_00594 6.13e-148 - - - S - - - Protein of unknown function (DUF4125)
PHOPOLEM_00595 0.0 - - - S - - - Domain of unknown function (DUF4037)
PHOPOLEM_00596 2.04e-275 - - - EGP ko:K08156,ko:K19577 - ko00000,ko02000 Major Facilitator Superfamily
PHOPOLEM_00598 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
PHOPOLEM_00599 2.38e-244 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
PHOPOLEM_00600 0.0 - - - G ko:K03292 - ko00000 Psort location CytoplasmicMembrane, score 10.00
PHOPOLEM_00601 4.24e-125 - - - S ko:K06889 - ko00000 Serine aminopeptidase, S33
PHOPOLEM_00602 1.76e-269 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
PHOPOLEM_00603 1.83e-178 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PHOPOLEM_00604 0.0 - 4.2.1.53 - S ko:K10254 - ko00000,ko01000 MCRA family
PHOPOLEM_00605 1.74e-132 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
PHOPOLEM_00606 6.11e-273 senX3 2.7.13.3 - T ko:K07768 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 ATPase histidine kinase DNA gyrase B HSP90 domain protein
PHOPOLEM_00607 3.36e-55 - - - - - - - -
PHOPOLEM_00608 5.66e-279 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
PHOPOLEM_00609 6.95e-212 - - - S - - - CHAP domain
PHOPOLEM_00610 2.31e-121 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC/P60 family
PHOPOLEM_00611 1.53e-242 - - - T - - - Universal stress protein family
PHOPOLEM_00612 7.52e-95 - - - O - - - OsmC-like protein
PHOPOLEM_00613 2.4e-232 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PHOPOLEM_00614 2.42e-166 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 dihydrofolate reductase
PHOPOLEM_00615 1.79e-111 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 low molecular weight
PHOPOLEM_00617 3.01e-254 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
PHOPOLEM_00618 1.25e-203 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
PHOPOLEM_00622 1.48e-157 - 5.1.3.2 - GM ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 ADP-glyceromanno-heptose 6-epimerase activity
PHOPOLEM_00623 6.88e-128 - 3.1.4.52 - T ko:K14051 ko02024,ko02026,map02024,map02026 ko00000,ko00001,ko01000 Putative diguanylate phosphodiesterase
PHOPOLEM_00624 4.08e-269 fucO 1.1.1.77, 1.1.99.37, 1.2.98.1 - C ko:K00048,ko:K17067 ko00625,ko00630,ko00640,ko00680,ko01120,ko01200,map00625,map00630,map00640,map00680,map01120,map01200 ko00000,ko00001,ko01000 Iron-containing alcohol dehydrogenase
PHOPOLEM_00625 1.5e-230 - - - M - - - Glycosyltransferase like family 2
PHOPOLEM_00626 0.0 - - - S - - - AI-2E family transporter
PHOPOLEM_00627 9.34e-294 - - - M - - - Glycosyl transferase family 21
PHOPOLEM_00628 4.56e-295 dacB 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-Ala-D-Ala carboxypeptidase 3 (S13) family
PHOPOLEM_00629 1.14e-254 tilS 2.4.2.8, 6.3.4.19 - J ko:K00760,ko:K04075 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
PHOPOLEM_00630 7.02e-128 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
PHOPOLEM_00631 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PHOPOLEM_00632 2.51e-150 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
PHOPOLEM_00633 1.68e-197 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
PHOPOLEM_00634 0.0 folK 2.7.6.3, 4.1.2.25 - H ko:K00950,ko:K13940 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PHOPOLEM_00635 5.18e-122 - - - S - - - Protein of unknown function (DUF3180)
PHOPOLEM_00636 6.48e-211 tesB - - I ko:K10805 ko01040,map01040 ko00000,ko00001,ko01000,ko01004 Thioesterase-like superfamily
PHOPOLEM_00637 0.0 yjjK - - S - - - ATP-binding cassette protein, ChvD family
PHOPOLEM_00638 1.9e-231 - - - V - - - Beta-lactamase
PHOPOLEM_00639 3.03e-96 fms 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
PHOPOLEM_00640 1.26e-198 - 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Cytidine and deoxycytidylate deaminase zinc-binding region
PHOPOLEM_00642 8.36e-99 - - - S - - - Protein conserved in bacteria
PHOPOLEM_00643 0.0 - - - S - - - Amidohydrolase family
PHOPOLEM_00644 0.0 - 2.5.1.49 - H ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 9.98
PHOPOLEM_00645 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
PHOPOLEM_00646 0.0 - 3.2.1.37, 3.2.1.55 GH43,GH51 G ko:K01198,ko:K01209 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
PHOPOLEM_00647 2.52e-238 - - - K ko:K02529,ko:K17640 - ko00000,ko03000 Bacterial regulatory proteins, lacI family
PHOPOLEM_00648 1.22e-309 - - - G ko:K02027,ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter periplasmic binding protein YcjN precursor K02027
PHOPOLEM_00649 8.4e-237 - - - U ko:K02025,ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PHOPOLEM_00650 4.06e-212 - - - P ko:K02026,ko:K10119,ko:K17243 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PHOPOLEM_00651 0.0 - 3.2.1.37 GH43 G ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
PHOPOLEM_00652 0.0 - 3.1.1.53 - G ko:K05970 - ko00000,ko01000 Glycosyl hydrolase family 2, sugar binding domain protein
PHOPOLEM_00653 1.71e-142 maa 2.3.1.18, 2.3.1.79 - S ko:K00633,ko:K00661 - ko00000,ko01000 Bacterial transferase hexapeptide repeat protein
PHOPOLEM_00654 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
PHOPOLEM_00655 7.3e-287 xylR - - GK - - - ROK family
PHOPOLEM_00657 2.63e-48 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
PHOPOLEM_00658 4.95e-248 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PHOPOLEM_00659 3.12e-221 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
PHOPOLEM_00660 6.78e-279 - - - E ko:K01999 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Receptor family ligand binding region
PHOPOLEM_00661 8.89e-199 - - - U ko:K01997 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
PHOPOLEM_00662 6.22e-249 - - - U ko:K01998 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
PHOPOLEM_00663 4.15e-193 livG - - E ko:K01995 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid ATP-binding cassette transporter
PHOPOLEM_00664 1.38e-158 livF - - E ko:K01995,ko:K01996 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ATPases associated with a variety of cellular activities
PHOPOLEM_00665 5.82e-144 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Belongs to the SUA5 family
PHOPOLEM_00666 1.55e-254 rfe 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 Glycosyl transferase family 4
PHOPOLEM_00667 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
PHOPOLEM_00668 2.33e-157 orn - - L ko:K13288 ko03008,map03008 ko00000,ko00001,ko01000,ko03009,ko03019 3'-to-5' exoribonuclease specific for small oligoribonucleotides
PHOPOLEM_00669 3.71e-210 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
PHOPOLEM_00670 0.0 - - - L - - - PIF1-like helicase
PHOPOLEM_00671 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
PHOPOLEM_00672 8.85e-129 ssb2 - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-strand binding protein family
PHOPOLEM_00673 0.0 pepO 3.4.24.11, 3.4.24.71 - O ko:K01389,ko:K01415,ko:K07386 ko04614,ko04640,ko04974,ko05010,map04614,map04640,map04974,map05010 ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 Peptidase family M13
PHOPOLEM_00674 5.71e-193 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
PHOPOLEM_00675 0.0 gltA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Citrate synthase, C-terminal domain
PHOPOLEM_00676 9.11e-216 dapD 2.3.1.117 - E ko:K00674 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
PHOPOLEM_00677 5e-106 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PHOPOLEM_00678 2.95e-263 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PHOPOLEM_00679 3.54e-240 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Cell division ATP-binding protein FtsE
PHOPOLEM_00680 7.75e-206 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in cellular division
PHOPOLEM_00681 9.94e-229 - - - D ko:K21471 - ko00000,ko01000,ko01002,ko01011 CHAP domain protein
PHOPOLEM_00682 5e-106 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
PHOPOLEM_00683 2.04e-205 glnH - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter, substrate-binding protein, family 3
PHOPOLEM_00684 8.89e-205 glnH - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter, substrate-binding protein, family 3
PHOPOLEM_00685 1.6e-202 glnH - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter, substrate-binding protein, family 3
PHOPOLEM_00686 1.26e-221 yecS - - E ko:K02029 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PHOPOLEM_00687 5.24e-187 tcyC 3.6.3.21 - E ko:K02028,ko:K02029 - ko00000,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
PHOPOLEM_00688 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
PHOPOLEM_00689 1.2e-185 - 5.4.99.28, 5.4.99.29 - J ko:K06177 - ko00000,ko01000,ko03009,ko03016 RNA pseudouridylate synthase
PHOPOLEM_00690 3.12e-290 sstT - - E ko:K07862 - ko00000,ko02000 Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
PHOPOLEM_00691 5.33e-243 - - - K - - - Periplasmic binding protein domain
PHOPOLEM_00693 7.37e-161 - - - G ko:K02026 - ko00000,ko00002,ko02000 ABC transporter permease
PHOPOLEM_00694 0.0 bga1 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.87
PHOPOLEM_00695 0.0 abfA1 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 arabinose metabolic process
PHOPOLEM_00696 0.0 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
PHOPOLEM_00697 0.0 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
PHOPOLEM_00698 8.78e-157 - - - K - - - Transcriptional regulatory protein, C terminal
PHOPOLEM_00699 2.25e-203 - - - T - - - His Kinase A (phosphoacceptor) domain
PHOPOLEM_00700 3.81e-107 - - - S - - - SnoaL-like domain
PHOPOLEM_00701 3.69e-183 coaX 2.7.1.33 - H ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
PHOPOLEM_00702 2.4e-308 coaBC 4.1.1.36, 6.3.2.5 - H ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PHOPOLEM_00703 0.0 - - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, family 5
PHOPOLEM_00704 8.06e-213 - - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PHOPOLEM_00705 5.4e-201 - - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PHOPOLEM_00706 3.93e-176 - - - EP ko:K02031 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 oligopeptide transport protein of the ABC superfamily, ATP-binding component
PHOPOLEM_00707 1.46e-177 - - - E ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ATPases associated with a variety of cellular activities
PHOPOLEM_00708 1.58e-240 cbs 2.5.1.47, 4.2.1.22 - E ko:K01697,ko:K01738 ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Pyridoxal-phosphate dependent enzyme
PHOPOLEM_00709 4.68e-280 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Cys/Met metabolism PLP-dependent enzyme
PHOPOLEM_00710 0.0 - - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
PHOPOLEM_00711 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
PHOPOLEM_00712 1.29e-117 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
PHOPOLEM_00713 4.58e-131 cysE - - J - - - COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PHOPOLEM_00714 0.0 aap1 - - E ko:K03294 - ko00000 aromatic amino acid transport protein AroP K03293
PHOPOLEM_00715 0.0 alr 5.1.1.1 - M ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PHOPOLEM_00716 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
PHOPOLEM_00717 1.02e-276 - - - P - - - Citrate transporter
PHOPOLEM_00719 3.78e-224 - - - S ko:K09936 ko02024,map02024 ko00000,ko00001,ko02000 Putative inner membrane exporter, YdcZ
PHOPOLEM_00721 0.0 tetM - - J ko:K18220 - br01600,ko00000,ko01504 Elongation factor G, domain IV
PHOPOLEM_00725 7.15e-129 - - - K - - - acetyltransferase
PHOPOLEM_00726 5.83e-143 glnP2 - - E ko:K02029 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PHOPOLEM_00727 2.14e-157 glnP - - E ko:K02029,ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PHOPOLEM_00728 6.84e-190 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ATP binding protein of ABC transporter for glutamate aspartate K02028
PHOPOLEM_00729 2.05e-203 glnH - - ET ko:K02030,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
PHOPOLEM_00730 1.42e-254 - 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PHOPOLEM_00731 9.73e-197 metQ - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 NLPA lipoprotein
PHOPOLEM_00732 9.6e-246 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PHOPOLEM_00733 4.35e-134 - - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Psort location CytoplasmicMembrane, score 9.99
PHOPOLEM_00734 1.92e-283 - 2.6.1.1, 2.6.1.2, 2.6.1.66, 2.6.1.83 - E ko:K00812,ko:K08969,ko:K10206,ko:K14260,ko:K14261 ko00220,ko00250,ko00270,ko00290,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
PHOPOLEM_00735 1.12e-08 metC1 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Cys/Met metabolism PLP-dependent enzyme
PHOPOLEM_00736 7.85e-59 - - - O - - - Glutaredoxin
PHOPOLEM_00737 1.89e-178 hflK - - O - - - prohibitin homologues
PHOPOLEM_00738 4.21e-16 - - - S ko:K07133 - ko00000 Domain of unknown function (DUF4143)
PHOPOLEM_00739 4.05e-98 - - - - - - - -
PHOPOLEM_00740 2e-165 - - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
PHOPOLEM_00741 1.55e-206 - - - M - - - Conserved repeat domain
PHOPOLEM_00742 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
PHOPOLEM_00743 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PHOPOLEM_00744 1.1e-232 yogA - - C - - - Zinc-binding dehydrogenase
PHOPOLEM_00745 2.09e-110 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PHOPOLEM_00746 9.55e-287 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PHOPOLEM_00747 7.41e-117 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
PHOPOLEM_00748 0.0 - - - M - - - Psort location CytoplasmicMembrane, score 9.26
PHOPOLEM_00749 6.65e-259 - 2.7.1.83 - G ko:K16328 ko00240,map00240 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
PHOPOLEM_00750 4.55e-242 yeiI 2.7.1.15, 2.7.1.45, 2.7.1.83 - G ko:K00852,ko:K00874,ko:K16328 ko00030,ko00240,ko01100,ko01120,ko01200,map00030,map00240,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 pfkB family carbohydrate kinase
PHOPOLEM_00751 1.06e-165 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 N-(5'phosphoribosyl)anthranilate (PRA) isomerase
PHOPOLEM_00752 2.58e-274 - - - C ko:K19954 - ko00000,ko01000 Iron-containing alcohol dehydrogenase
PHOPOLEM_00753 2.32e-235 rihB 3.2.2.1, 3.2.2.8 - F ko:K01239,ko:K01250,ko:K10213 ko00230,ko00240,ko00760,ko01100,map00230,map00240,map00760,map01100 ko00000,ko00001,ko01000 Inosine-uridine preferring nucleoside hydrolase
PHOPOLEM_00754 7.78e-314 - - - EGP - - - Major Facilitator Superfamily
PHOPOLEM_00755 4.87e-298 purD 6.3.3.1, 6.3.4.13 - F ko:K01945,ko:K11788 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
PHOPOLEM_00756 1.07e-242 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
PHOPOLEM_00757 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PHOPOLEM_00758 0.0 - - - L ko:K03502 - ko00000,ko03400 DNA-damage repair protein (DNA polymerase IV) K00961
PHOPOLEM_00759 1.79e-46 - - - - - - - -
PHOPOLEM_00760 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 CobB/CobQ-like glutamine amidotransferase domain
PHOPOLEM_00761 1.97e-175 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
PHOPOLEM_00762 7.01e-288 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
PHOPOLEM_00763 2.64e-289 - - - M - - - Glycosyl transferase 4-like domain
PHOPOLEM_00764 7.38e-253 ltaE 4.1.2.48 - E ko:K01620 ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 Beta-eliminating lyase
PHOPOLEM_00766 5.25e-241 - - - S ko:K03453 - ko00000 SBF-like CPA transporter family (DUF4137)
PHOPOLEM_00767 5.77e-81 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PHOPOLEM_00768 9.4e-105 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
PHOPOLEM_00769 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PHOPOLEM_00770 2.12e-295 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PHOPOLEM_00771 2.2e-134 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PHOPOLEM_00772 1.21e-98 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PHOPOLEM_00773 2.95e-305 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarA family
PHOPOLEM_00774 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase large chain, oligomerisation domain
PHOPOLEM_00775 1.42e-218 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
PHOPOLEM_00776 3.1e-138 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
PHOPOLEM_00778 0.0 ilvD 4.2.1.9 - H ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the IlvD Edd family
PHOPOLEM_00779 5.45e-61 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
PHOPOLEM_00780 4.29e-290 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PHOPOLEM_00781 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PHOPOLEM_00782 1.23e-172 - 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
PHOPOLEM_00783 3.54e-229 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PHOPOLEM_00784 4.49e-159 serB 3.1.3.3 - E ko:K01079 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01009 haloacid dehalogenase-like hydrolase
PHOPOLEM_00785 0.0 arc - - O ko:K13527 ko03050,map03050 ko00000,ko00001,ko00002,ko03051 AAA ATPase forming ring-shaped complexes
PHOPOLEM_00786 0.0 dop 3.5.1.119 - S ko:K20814 - ko00000,ko01000,ko03051 Pup-ligase protein
PHOPOLEM_00787 5.52e-204 - 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase family
PHOPOLEM_00788 5.14e-34 pup - - S ko:K13570 - ko00000,ko04121 Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
PHOPOLEM_00789 0.0 pafA 6.3.1.19 - O ko:K13571 - ko00000,ko00002,ko01000,ko03051 Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
PHOPOLEM_00790 3.79e-181 - - - C - - - FMN binding
PHOPOLEM_00791 4.35e-75 - - - - - - - -
PHOPOLEM_00792 4.7e-57 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Belongs to the bacterial histone-like protein family
PHOPOLEM_00793 0.0 - - - S - - - Lysylphosphatidylglycerol synthase TM region
PHOPOLEM_00794 0.0 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Adenylosuccinate lyase C-terminal
PHOPOLEM_00795 0.0 - - - S - - - PGAP1-like protein
PHOPOLEM_00796 2.34e-102 - - - - - - - -
PHOPOLEM_00797 7.17e-234 - - - S ko:K07114 - ko00000,ko02000 von Willebrand factor (vWF) type A domain
PHOPOLEM_00798 1.78e-242 - - - S ko:K07114 - ko00000,ko02000 von Willebrand factor (vWF) type A domain
PHOPOLEM_00799 3.29e-121 - - - - - - - -
PHOPOLEM_00800 3.01e-224 - - - S - - - Protein of unknown function DUF58
PHOPOLEM_00801 1.53e-232 moxR - - S ko:K03924 - ko00000,ko01000 ATPase family associated with various cellular activities (AAA)
PHOPOLEM_00802 9.46e-176 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PHOPOLEM_00803 1.2e-117 - - - S - - - LytR cell envelope-related transcriptional attenuator
PHOPOLEM_00804 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
PHOPOLEM_00805 1.74e-38 - - - S - - - Proteins of 100 residues with WXG
PHOPOLEM_00806 8.75e-169 - - - - - - - -
PHOPOLEM_00807 2.04e-169 phoP - - KT ko:K02483 - ko00000,ko02022 Response regulator receiver domain protein
PHOPOLEM_00808 0.0 phoR 2.7.13.3 - T ko:K02484 - ko00000,ko01000,ko01001,ko02022 ATPase histidine kinase DNA gyrase B HSP90 domain protein
PHOPOLEM_00809 6.1e-88 cspB - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
PHOPOLEM_00810 3.51e-243 - - - S - - - Protein of unknown function (DUF3027)
PHOPOLEM_00811 1.12e-241 uspA - - T - - - Belongs to the universal stress protein A family
PHOPOLEM_00812 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 ATPase family associated with various cellular activities (AAA)
PHOPOLEM_00813 0.0 codA 3.5.4.1, 3.5.4.21 - F ko:K01485,ko:K03365 ko00240,ko00330,ko01100,map00240,map00330,map01100 ko00000,ko00001,ko01000 Amidohydrolase family
PHOPOLEM_00814 0.0 - - - QT - - - Purine catabolism regulatory protein-like family
PHOPOLEM_00815 7.96e-316 proP - - EGP ko:K03762 - ko00000,ko02000 Sugar (and other) transporter
PHOPOLEM_00816 1.71e-180 - 3.5.2.10 - S ko:K01470 ko00330,map00330 ko00000,ko00001,ko01000 Creatinine amidohydrolase
PHOPOLEM_00817 1.25e-299 - - - S - - - Domain of Unknown Function (DUF349)
PHOPOLEM_00818 0.0 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Histidyl-tRNA synthetase
PHOPOLEM_00819 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
PHOPOLEM_00820 0.0 glnP - - E ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PHOPOLEM_00821 1.01e-179 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
PHOPOLEM_00822 2.25e-185 gluA - - E ko:K10008 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding protein of ABC transporter for glutamate K02028
PHOPOLEM_00823 4.19e-195 gluB - - ET ko:K10005 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
PHOPOLEM_00824 1.04e-144 gluC - - E ko:K10006 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PHOPOLEM_00825 1.44e-256 gluD - - E ko:K10007 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PHOPOLEM_00826 4.93e-244 - - - S - - - Polyphosphate kinase 2 (PPK2)
PHOPOLEM_00827 0.0 - - - L - - - DEAD DEAH box helicase
PHOPOLEM_00828 0.0 rarA - - L ko:K07478 - ko00000 Recombination factor protein RarA
PHOPOLEM_00829 5.1e-170 mtrA - - KT ko:K07670 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
PHOPOLEM_00830 0.0 mtrB 2.7.13.3 - T ko:K07636,ko:K07654 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
PHOPOLEM_00831 0.0 lpqB - - S - - - Lipoprotein LpqB beta-propeller domain
PHOPOLEM_00832 4.37e-219 - - - G ko:K02058,ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein domain
PHOPOLEM_00833 0.0 - 3.6.3.17 - G ko:K02056,ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
PHOPOLEM_00834 2.35e-230 ytfT - - U ko:K02057,ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid transport system / permease component
PHOPOLEM_00835 1.77e-219 - - - U ko:K02057,ko:K10440,ko:K17209 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid transport system / permease component
PHOPOLEM_00836 0.0 - - - EGP - - - Major Facilitator Superfamily
PHOPOLEM_00837 0.0 dppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, family 5
PHOPOLEM_00838 1.25e-147 clpP1 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
PHOPOLEM_00839 2.68e-160 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
PHOPOLEM_00840 5.76e-308 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PHOPOLEM_00843 2.92e-315 nhaA - - P ko:K03313 - ko00000,ko02000 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
PHOPOLEM_00844 1.23e-151 safC - - S - - - O-methyltransferase
PHOPOLEM_00845 9.33e-224 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 4Fe-4S dicluster domain
PHOPOLEM_00846 0.0 sdhA 1.3.5.1, 1.3.5.4, 1.4.3.16 - C ko:K00239,ko:K00278 ko00020,ko00190,ko00250,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00250,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 Succinate dehydrogenase flavoprotein subunit
PHOPOLEM_00847 0.0 dprA - - LU ko:K04096 - ko00000 DNA recombination-mediator protein A
PHOPOLEM_00848 0.0 comM - - O ko:K07391 - ko00000 Magnesium chelatase, subunit ChlI C-terminal
PHOPOLEM_00849 1.85e-108 yraN - - L ko:K07460 - ko00000 Belongs to the UPF0102 family
PHOPOLEM_00850 4.32e-211 pdxY 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
PHOPOLEM_00851 0.0 - 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Aminotransferase class-V
PHOPOLEM_00852 1.88e-124 - - - S - - - ECF-type riboflavin transporter, S component
PHOPOLEM_00853 0.0 ykoD - - P ko:K16784,ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
PHOPOLEM_00854 1.1e-192 cbiQ - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
PHOPOLEM_00855 2.42e-245 asnC - - K ko:K03718 - ko00000,ko03000 helix_turn_helix ASNC type
PHOPOLEM_00856 1.28e-182 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
PHOPOLEM_00857 0.0 - - - MV ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
PHOPOLEM_00858 1.37e-165 - - - K - - - helix_turn_helix, Lux Regulon
PHOPOLEM_00859 0.0 - - - T - - - Histidine kinase
PHOPOLEM_00860 0.0 pip 3.4.11.5 - S ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 alpha/beta hydrolase fold
PHOPOLEM_00861 2.56e-179 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PHOPOLEM_00862 7.45e-258 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
PHOPOLEM_00863 6.19e-24 yccF - - S - - - Inner membrane component domain
PHOPOLEM_00864 1.1e-16 - - - - - - - -
PHOPOLEM_00865 0.0 - - - U - - - Drug resistance MFS transporter, drug H antiporter-2 family
PHOPOLEM_00866 8.2e-180 - - - - - - - -
PHOPOLEM_00867 1.03e-226 - - - S - - - Conserved hypothetical protein 698
PHOPOLEM_00868 1.27e-274 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter family protein
PHOPOLEM_00869 4.29e-202 - - - C ko:K07138 - ko00000 Domain of unknown function (DUF362)
PHOPOLEM_00870 5.87e-104 - - - F - - - uridine kinase
PHOPOLEM_00871 1.26e-103 - - - S - - - ECF transporter, substrate-specific component
PHOPOLEM_00872 4.1e-187 - - - S ko:K07090 - ko00000 Sulfite exporter TauE/SafE
PHOPOLEM_00873 4.68e-182 - - - K - - - helix_turn_helix, arabinose operon control protein
PHOPOLEM_00874 5.12e-206 - - - G - - - Phosphoglycerate mutase family
PHOPOLEM_00875 1.78e-300 rutG - - F ko:K02824,ko:K03458 - ko00000,ko02000 Permease family
PHOPOLEM_00876 3.76e-168 - - - S - - - Enoyl-(Acyl carrier protein) reductase
PHOPOLEM_00877 0.0 - - - JKL - - - helicase superfamily c-terminal domain
PHOPOLEM_00878 3.34e-173 - - - V ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
PHOPOLEM_00879 2.01e-182 - - - V ko:K02068 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
PHOPOLEM_00880 5.55e-305 - - - S - - - Putative esterase
PHOPOLEM_00881 0.0 lysX - - S - - - Uncharacterised conserved protein (DUF2156)
PHOPOLEM_00882 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
PHOPOLEM_00883 7.18e-190 - - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
PHOPOLEM_00884 3.15e-303 - 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I II
PHOPOLEM_00885 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PHOPOLEM_00886 5.43e-233 opcA - - G - - - Glucose-6-phosphate dehydrogenase subunit
PHOPOLEM_00887 1.43e-187 pgl 3.1.1.31 - G ko:K01057 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
PHOPOLEM_00888 3.28e-105 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
PHOPOLEM_00889 1.05e-135 - - - M - - - Protein of unknown function (DUF3737)
PHOPOLEM_00890 6.02e-175 - - - E - - - AzlC protein
PHOPOLEM_00891 1.32e-69 azlD - - E - - - Branched-chain amino acid transport protein (AzlD)
PHOPOLEM_00892 0.0 cstA - - T ko:K06200 - ko00000 5TM C-terminal transporter carbon starvation CstA
PHOPOLEM_00893 1.2e-53 - - - S - - - Selenoprotein, putative
PHOPOLEM_00894 1.11e-227 - 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Glycosyl hydrolase family 3 N-terminal domain protein
PHOPOLEM_00895 0.0 - - - S ko:K09118 - ko00000 Uncharacterised protein family (UPF0182)
PHOPOLEM_00896 5e-135 - 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
PHOPOLEM_00897 8.2e-145 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
PHOPOLEM_00898 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PHOPOLEM_00899 7.13e-313 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
PHOPOLEM_00900 4.86e-97 - - - D - - - Septum formation initiator
PHOPOLEM_00901 1.62e-133 - - - S ko:K09009 - ko00000 Protein of unknown function (DUF501)
PHOPOLEM_00902 4.49e-233 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 Ppx/GppA phosphatase family
PHOPOLEM_00904 1.58e-120 - - - - - - - -
PHOPOLEM_00905 0.0 sdaA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase alpha chain
PHOPOLEM_00906 1.12e-95 fkbP 5.2.1.8 - G ko:K01802 - ko00000,ko01000 Peptidyl-prolyl cis-trans
PHOPOLEM_00907 2.04e-105 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PHOPOLEM_00908 8.07e-202 hlyIII - - S ko:K11068 - ko00000,ko02042 Haemolysin-III related
PHOPOLEM_00909 0.0 pdtaS 2.7.13.3 - T ko:K00936 - ko00000,ko00002,ko01000,ko01001,ko02022 ATPase histidine kinase DNA gyrase B HSP90 domain protein
PHOPOLEM_00910 3.32e-61 whiB - - K ko:K18955 - ko00000,ko03000 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
PHOPOLEM_00911 0.0 - - - D ko:K03466 - ko00000,ko03036 FtsK/SpoIIIE family
PHOPOLEM_00912 1.37e-218 lytR2 - - K - - - Cell envelope-related transcriptional attenuator domain
PHOPOLEM_00914 5.03e-301 yvhJ - - K - - - Cell envelope-related transcriptional attenuator domain
PHOPOLEM_00915 2.32e-71 whiB2 - - K ko:K18955 - ko00000,ko03000 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
PHOPOLEM_00916 0.0 - - - S - - - Glycosyl transferase, family 2
PHOPOLEM_00917 3.77e-290 - - - - - - - -
PHOPOLEM_00918 6.14e-93 - - - S - - - Zincin-like metallopeptidase
PHOPOLEM_00919 2.56e-196 - - - T - - - Eukaryotic phosphomannomutase
PHOPOLEM_00920 2.31e-178 pyrE_1 - - S - - - Phosphoribosyl transferase domain
PHOPOLEM_00921 1.99e-238 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
PHOPOLEM_00922 1.74e-165 cseB - - T - - - Response regulator receiver domain protein
PHOPOLEM_00923 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
PHOPOLEM_00924 8.46e-133 carD - - K ko:K07736 - ko00000,ko03000 CarD-like/TRCF domain
PHOPOLEM_00925 3.22e-114 ispF 2.7.7.60, 4.6.1.12 - H ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
PHOPOLEM_00926 1.58e-179 znuB - - U ko:K02075 - ko00000,ko00002,ko02000 ABC 3 transport family
PHOPOLEM_00927 7.98e-205 - - - P ko:K02074 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
PHOPOLEM_00928 1.3e-227 - - - P ko:K02077 - ko00000,ko00002,ko02000 Zinc-uptake complex component A periplasmic
PHOPOLEM_00929 5.52e-207 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PHOPOLEM_00930 0.0 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
PHOPOLEM_00931 4.45e-149 coaE 2.7.1.24 - H ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
PHOPOLEM_00932 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
PHOPOLEM_00934 5.3e-201 terC - - P ko:K05794 - ko00000 Integral membrane protein, TerC family
PHOPOLEM_00935 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Pyruvate kinase
PHOPOLEM_00937 5.04e-26 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
PHOPOLEM_00939 2.85e-130 - 3.2.1.21 - G ko:K05350 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Glycosyl hydrolase family 1
PHOPOLEM_00940 1.78e-118 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases)
PHOPOLEM_00941 3.05e-152 - 5.1.3.15 - G ko:K01792 ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Aldose 1-epimerase
PHOPOLEM_00942 8.64e-156 pdtaR - - T ko:K22010 - ko00000,ko00002,ko02022 Response regulator receiver domain protein
PHOPOLEM_00943 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PHOPOLEM_00944 3.51e-222 - - - L - - - NIF3 (NGG1p interacting factor 3)
PHOPOLEM_00945 4.34e-159 - - - L - - - NUDIX domain
PHOPOLEM_00946 0.0 glgX 3.2.1.68 CBM48,GH13 G ko:K01214 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 13 family
PHOPOLEM_00947 1.86e-268 - - - - - - - -
PHOPOLEM_00949 1.8e-316 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
PHOPOLEM_00950 2.64e-92 - - - K - - - Acetyltransferase (GNAT) domain
PHOPOLEM_00951 8.04e-101 - - - K ko:K03826 - ko00000,ko01000 Acetyltransferase (GNAT) domain
PHOPOLEM_00952 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
PHOPOLEM_00953 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
PHOPOLEM_00954 0.0 pta 2.3.1.8 - C ko:K13788 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphate acetyltransferase
PHOPOLEM_00955 8.03e-296 ackA 2.7.2.1 - H ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PHOPOLEM_00956 0.0 yrhL - - I - - - Psort location CytoplasmicMembrane, score 9.99
PHOPOLEM_00957 1.23e-311 pbuX - - F ko:K03458 - ko00000 Permease family
PHOPOLEM_00958 2.66e-138 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
PHOPOLEM_00959 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
PHOPOLEM_00960 3.23e-80 - - - S - - - Domain of unknown function (DUF4418)
PHOPOLEM_00961 1.96e-273 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
PHOPOLEM_00962 6.08e-191 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
PHOPOLEM_00963 3.17e-142 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PHOPOLEM_00964 1.3e-57 - - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
PHOPOLEM_00965 9.46e-167 - 5.4.2.12 - G ko:K15634 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Phosphoglycerate mutase family
PHOPOLEM_00966 8.09e-79 - - - S - - - Bacterial protein of unknown function (DUF948)
PHOPOLEM_00967 6.83e-50 - - - - - - - -
PHOPOLEM_00968 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PHOPOLEM_00969 1.75e-105 ruvX - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PHOPOLEM_00970 2.36e-253 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PHOPOLEM_00971 3.69e-95 - 3.4.23.43 - S ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 Type IV leader peptidase family
PHOPOLEM_00972 1.64e-282 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
PHOPOLEM_00973 0.0 aroB 2.7.1.71, 4.2.3.4 - H ko:K01735,ko:K13829 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
PHOPOLEM_00974 3.9e-105 aroQ 4.2.1.10 - E ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a trans-dehydration via an enolate intermediate
PHOPOLEM_00975 0.0 - 3.2.1.1, 3.2.1.41 CBM48,GH13 M ko:K01176,ko:K01200 ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973 ko00000,ko00001,ko01000 Aamy_C
PHOPOLEM_00976 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
PHOPOLEM_00977 0.0 - - - S - - - L,D-transpeptidase catalytic domain
PHOPOLEM_00978 0.0 sufB - - O ko:K09014 - ko00000 FeS assembly protein SufB
PHOPOLEM_00979 7.47e-300 sufD - - O ko:K09015 - ko00000 FeS assembly protein SufD
PHOPOLEM_00980 1.14e-183 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
PHOPOLEM_00981 1.86e-304 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PHOPOLEM_00982 6.78e-128 iscU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
PHOPOLEM_00983 1.6e-140 - - - S - - - Iron-sulfur cluster assembly protein
PHOPOLEM_00984 5.57e-310 glgC 2.7.7.27 - H ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
PHOPOLEM_00985 1.18e-205 spoU2 - - J - - - SpoU rRNA Methylase family
PHOPOLEM_00987 9.78e-188 - 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
PHOPOLEM_00988 1.81e-74 hit - - FG ko:K02503 - ko00000,ko04147 Scavenger mRNA decapping enzyme C-term binding
PHOPOLEM_00989 1.16e-266 phoH - - T ko:K06217 - ko00000 PhoH-like protein
PHOPOLEM_00990 1.14e-133 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PHOPOLEM_00991 0.0 corC - - S - - - CBS domain
PHOPOLEM_00992 2.58e-228 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PHOPOLEM_00993 0.0 fadD2 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme
PHOPOLEM_00994 3.43e-260 pntA 1.6.1.2 - C ko:K00324 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 NAD(P) transhydrogenase subunit alpha part 1 K00324
PHOPOLEM_00995 1.02e-57 pntAB 1.6.1.2 - C ko:K00324 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 4TM region of pyridine nucleotide transhydrogenase, mitoch
PHOPOLEM_00996 0.0 pntB 1.6.1.2 - C ko:K00325 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
PHOPOLEM_00997 0.0 - - - S - - - Psort location Cytoplasmic, score 8.87
PHOPOLEM_00998 1.07e-280 - - - G - - - Transmembrane secretion effector
PHOPOLEM_00999 1.02e-152 - - - K - - - Bacterial regulatory proteins, tetR family
PHOPOLEM_01000 3.96e-53 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
PHOPOLEM_01001 4.43e-95 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
PHOPOLEM_01002 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PHOPOLEM_01004 2.96e-242 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PHOPOLEM_01005 0.0 uvrA3 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
PHOPOLEM_01006 3.74e-41 - - - EGP ko:K08177,ko:K19577 - ko00000,ko02000 Major facilitator Superfamily
PHOPOLEM_01007 9.97e-36 yhjX - - EGP ko:K08177 - ko00000,ko02000 Major facilitator Superfamily
PHOPOLEM_01008 1.08e-249 - - - S ko:K06889 - ko00000 alpha beta
PHOPOLEM_01009 1.29e-127 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
PHOPOLEM_01010 1.47e-121 - - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PHOPOLEM_01011 1e-76 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PHOPOLEM_01012 1.07e-94 - - - K - - - Acetyltransferase (GNAT) domain
PHOPOLEM_01014 8.14e-290 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Amino-transferase class IV
PHOPOLEM_01015 3.02e-174 - - - S - - - UPF0126 domain
PHOPOLEM_01016 7.89e-46 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
PHOPOLEM_01017 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
PHOPOLEM_01018 1.82e-297 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
PHOPOLEM_01019 9.78e-188 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Oxidoreductase, short chain dehydrogenase reductase family protein
PHOPOLEM_01020 0.0 - - - C - - - Acyl-CoA reductase (LuxC)
PHOPOLEM_01021 1.23e-276 - - - H - - - long-chain-fatty-acid--luciferin-component ligase, acyl-protein synthase
PHOPOLEM_01022 1.1e-297 - - - F - - - Psort location CytoplasmicMembrane, score 10.00
PHOPOLEM_01023 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase NADPH large subunit
PHOPOLEM_01024 0.0 gltD 1.4.1.13, 1.4.1.14 - C ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
PHOPOLEM_01025 3.85e-98 - - - - - - - -
PHOPOLEM_01026 0.0 glgA 2.4.1.342 GT4 G ko:K16148 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000,ko01003 Starch synthase catalytic domain
PHOPOLEM_01027 2.93e-198 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
PHOPOLEM_01028 4.99e-251 trmI 2.1.1.219, 2.1.1.220 - J ko:K07442 - ko00000,ko01000,ko03016 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
PHOPOLEM_01029 1.67e-128 sixA - - T ko:K08296 - ko00000,ko01000 Phosphoglycerate mutase family
PHOPOLEM_01030 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
PHOPOLEM_01031 1.42e-202 metF 1.5.1.20 - E ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Methylenetetrahydrofolate reductase
PHOPOLEM_01032 0.0 glnE 2.7.7.42, 2.7.7.89 - H ko:K00982 - ko00000,ko01000 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
PHOPOLEM_01033 8.48e-241 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
PHOPOLEM_01034 1.06e-96 pyrI - - F ko:K00610 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002 Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
PHOPOLEM_01035 0.0 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
PHOPOLEM_01036 9.32e-225 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the OMP decarboxylase family. Type 2 subfamily
PHOPOLEM_01037 8.43e-197 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
PHOPOLEM_01038 8.22e-230 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
PHOPOLEM_01039 9.36e-160 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PHOPOLEM_01040 6.03e-210 - - - K - - - Bacterial regulatory helix-turn-helix protein, lysR family
PHOPOLEM_01041 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
PHOPOLEM_01042 1.87e-08 - - - J - - - Acetyltransferase (GNAT) domain
PHOPOLEM_01043 4.36e-89 arsC 1.20.4.1, 2.8.4.2 - T ko:K03741,ko:K18701 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PHOPOLEM_01044 5.42e-278 - 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Psort location Cytoplasmic, score 8.87
PHOPOLEM_01045 3.66e-157 - 2.3.1.18, 2.3.1.79 - S ko:K00633,ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
PHOPOLEM_01046 6.64e-67 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
PHOPOLEM_01047 1.68e-179 - - - S - - - SdpI/YhfL protein family
PHOPOLEM_01048 3.2e-157 - 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
PHOPOLEM_01049 0.0 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PHOPOLEM_01050 5.36e-161 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
PHOPOLEM_01053 1.81e-81 - - - - - - - -
PHOPOLEM_01054 9.76e-125 - - - M - - - Peptidase family M23
PHOPOLEM_01055 0.0 fadD1 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme
PHOPOLEM_01056 0.0 - - - G - - - ABC transporter substrate-binding protein
PHOPOLEM_01057 1.58e-305 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the isocitrate and isopropylmalate dehydrogenases family
PHOPOLEM_01058 2.74e-266 guaB3 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 IMP dehydrogenase family protein
PHOPOLEM_01059 5.78e-139 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Exonuclease, DNA polymerase III, epsilon subunit family
PHOPOLEM_01060 4.35e-94 - - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
PHOPOLEM_01061 2.71e-316 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PHOPOLEM_01062 6.81e-89 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
PHOPOLEM_01063 7.33e-183 gpmB 3.1.3.85, 5.4.2.11 - G ko:K01834,ko:K22306 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Phosphoglycerate mutase family
PHOPOLEM_01064 1.26e-169 - - - - - - - -
PHOPOLEM_01066 1.2e-298 - - - K - - - Fic/DOC family
PHOPOLEM_01067 1.17e-92 pdxH - - S ko:K07006 - ko00000 Pfam:Pyridox_oxidase
PHOPOLEM_01068 0.0 - - - M - - - domain protein
PHOPOLEM_01071 1.72e-210 gpmB 3.1.3.85, 5.4.2.11 - G ko:K01834,ko:K22306 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Phosphoglycerate mutase family
PHOPOLEM_01072 1.48e-219 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
PHOPOLEM_01073 3.19e-181 - - - ET ko:K10005 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
PHOPOLEM_01074 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
PHOPOLEM_01075 1.6e-137 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Helix-hairpin-helix motif
PHOPOLEM_01076 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein
PHOPOLEM_01077 1.18e-225 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
PHOPOLEM_01078 7.17e-119 tsaE - - S ko:K06925 - ko00000,ko03016 Threonylcarbamoyl adenosine biosynthesis protein TsaE
PHOPOLEM_01079 6.89e-190 yeaZ - - O ko:K14742 - ko00000,ko03016 Glycoprotease family
PHOPOLEM_01080 1.73e-133 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 FR47-like protein
PHOPOLEM_01081 1.13e-250 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PHOPOLEM_01083 5.47e-152 yoaP - - E - - - YoaP-like
PHOPOLEM_01084 1.07e-237 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
PHOPOLEM_01085 3.51e-154 - - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
PHOPOLEM_01086 2.39e-93 - - - K - - - MerR family regulatory protein
PHOPOLEM_01087 2.21e-253 adh 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Zinc-binding dehydrogenase
PHOPOLEM_01088 1.31e-185 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
PHOPOLEM_01089 7.46e-282 - 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Psort location Cytoplasmic, score 8.87
PHOPOLEM_01090 1.36e-98 - - - S - - - Psort location CytoplasmicMembrane, score
PHOPOLEM_01091 8.66e-232 - - - P - - - Cation efflux family
PHOPOLEM_01094 1.62e-141 - - - - ko:K03646 - ko00000,ko02000 -
PHOPOLEM_01095 2.34e-193 - - - - - - - -
PHOPOLEM_01096 5.46e-186 mazG 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 Psort location Cytoplasmic, score 8.87
PHOPOLEM_01097 0.0 - 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
PHOPOLEM_01098 5.09e-226 - - - S - - - IMP dehydrogenase activity
PHOPOLEM_01099 0.0 ybiT - - S ko:K06158 - ko00000,ko03012 ABC transporter
PHOPOLEM_01100 4.74e-145 pncA 3.5.1.19 - Q ko:K08281 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Isochorismatase family
PHOPOLEM_01101 4.53e-88 ogt 2.1.1.63 - L ko:K00567,ko:K07443 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PHOPOLEM_01103 2.77e-19 - - - - - - - -
PHOPOLEM_01104 0.0 - - - S - - - Psort location Cytoplasmic, score 8.87
PHOPOLEM_01105 1.68e-181 - - - S - - - Domain of unknown function (DUF4194)
PHOPOLEM_01106 0.0 - - - S - - - Psort location Cytoplasmic, score 8.87
PHOPOLEM_01107 2.14e-282 - - - S - - - Psort location Cytoplasmic, score 8.87
PHOPOLEM_01108 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
PHOPOLEM_01109 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
PHOPOLEM_01110 1.7e-233 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Shikimate dehydrogenase substrate binding domain
PHOPOLEM_01111 7.62e-219 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
PHOPOLEM_01112 2.1e-219 whiA - - K ko:K09762 - ko00000 May be required for sporulation
PHOPOLEM_01113 3.72e-281 pgk 2.7.2.3, 5.3.1.1 - F ko:K00927,ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Phosphoglycerate kinase
PHOPOLEM_01114 4.01e-191 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
PHOPOLEM_01115 2.47e-44 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase SecG subunit
PHOPOLEM_01116 1.58e-208 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
PHOPOLEM_01117 0.0 aspC 2.6.1.1, 2.6.1.2, 2.6.1.66 - E ko:K00812,ko:K08969,ko:K14260 ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase, class I II
PHOPOLEM_01118 3.51e-11 - - - H ko:K03811 - ko00000,ko02000 Nicotinamide mononucleotide transporter
PHOPOLEM_01119 4.04e-148 - - - H ko:K03811 - ko00000,ko02000 Nicotinamide mononucleotide transporter
PHOPOLEM_01120 4.03e-57 nadR - - H - - - ATPase kinase involved in NAD metabolism
PHOPOLEM_01121 4.69e-260 tal 2.2.1.2 - H ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
PHOPOLEM_01122 0.0 tkt 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the transketolase family
PHOPOLEM_01123 3.25e-250 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
PHOPOLEM_01124 6.98e-265 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
PHOPOLEM_01125 1.58e-201 - - - G - - - Fructosamine kinase
PHOPOLEM_01126 1.44e-199 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
PHOPOLEM_01127 3.95e-200 - - - S - - - PAC2 family
PHOPOLEM_01135 3.74e-48 - - - - - - - -
PHOPOLEM_01136 2.22e-98 garA - - T - - - Inner membrane component of T3SS, cytoplasmic domain
PHOPOLEM_01137 3.87e-118 merR2 - - K - - - helix_turn_helix, mercury resistance
PHOPOLEM_01138 1.54e-80 - - - - - - - -
PHOPOLEM_01139 5.93e-181 nt5e 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 HAD-hyrolase-like
PHOPOLEM_01140 2.24e-81 rbpA - - K - - - Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
PHOPOLEM_01141 0.0 helY - - L ko:K03727 - ko00000,ko01000 DEAD DEAH box helicase
PHOPOLEM_01142 2.4e-73 - - - - - - - -
PHOPOLEM_01143 0.0 - - - K - - - WYL domain
PHOPOLEM_01144 0.0 ugp 2.7.7.9 - G ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
PHOPOLEM_01146 8.64e-92 - - - - - - - -
PHOPOLEM_01147 0.0 der - - F ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
PHOPOLEM_01148 9.79e-184 rluB 5.4.99.19, 5.4.99.22 - J ko:K06178,ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
PHOPOLEM_01149 1.39e-206 - - - U ko:K06188 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
PHOPOLEM_01150 1.69e-48 - - - - - - - -
PHOPOLEM_01151 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
PHOPOLEM_01152 0.0 - - - - - - - -
PHOPOLEM_01153 1.1e-205 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
PHOPOLEM_01154 5.48e-281 sucC 6.2.1.5 - F ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
PHOPOLEM_01155 6.16e-129 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PHOPOLEM_01156 3.98e-83 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit
PHOPOLEM_01157 3.38e-256 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
PHOPOLEM_01158 1.34e-137 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
PHOPOLEM_01159 2.73e-129 ruvC 3.1.22.4 - L ko:K01159 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
PHOPOLEM_01160 2.38e-172 yebC - - K - - - transcriptional regulatory protein
PHOPOLEM_01161 2.88e-144 pgsA1 2.7.8.11, 2.7.8.5 - I ko:K00995,ko:K00999 ko00562,ko00564,ko01100,ko04070,map00562,map00564,map01100,map04070 ko00000,ko00001,ko01000 CDP-alcohol phosphatidyltransferase
PHOPOLEM_01162 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PHOPOLEM_01163 3.22e-182 - - - S - - - Bacterial protein of unknown function (DUF881)
PHOPOLEM_01164 2.68e-64 sbp - - S - - - Protein of unknown function (DUF1290)
PHOPOLEM_01165 2.27e-222 - - - S - - - Bacterial protein of unknown function (DUF881)
PHOPOLEM_01166 8.44e-134 pgsA2 2.7.8.41, 2.7.8.5 - I ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PHOPOLEM_01167 1.24e-199 hisG 2.4.2.17 - F ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 ATP phosphoribosyltransferase
PHOPOLEM_01168 1.2e-54 hisE 3.6.1.31 - E ko:K01523 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Phosphoribosyl-ATP pyrophosphohydrolase
PHOPOLEM_01169 2.25e-137 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribulose-phosphate 3-epimerase
PHOPOLEM_01170 2.39e-231 lgt - - M - - - Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PHOPOLEM_01171 3.89e-208 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
PHOPOLEM_01172 0.0 trpB 4.2.1.20 - E ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
PHOPOLEM_01173 0.0 trpE 4.1.3.27 - E ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PHOPOLEM_01174 1.12e-95 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
PHOPOLEM_01175 5.63e-178 hisF 4.1.3.27 - E ko:K01657,ko:K02500 ko00340,ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00340,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
PHOPOLEM_01176 9.19e-287 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
PHOPOLEM_01177 5.62e-228 cdsA 2.7.7.41 - I ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Cytidylyltransferase family
PHOPOLEM_01178 6.26e-119 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
PHOPOLEM_01179 2.04e-172 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
PHOPOLEM_01181 6.23e-184 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PHOPOLEM_01182 7.95e-183 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
PHOPOLEM_01183 1.22e-107 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
PHOPOLEM_01184 0.0 fadD3 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 long-chain-fatty acid CoA ligase
PHOPOLEM_01185 1.25e-157 - - - - - - - -
PHOPOLEM_01186 1.85e-83 intA - - L - - - Phage integrase family
PHOPOLEM_01188 7.48e-214 - - - M - - - Bacteriophage peptidoglycan hydrolase
PHOPOLEM_01191 6.86e-129 - - - - - - - -
PHOPOLEM_01192 8.54e-263 - - - - - - - -
PHOPOLEM_01193 1.15e-59 - - - - - - - -
PHOPOLEM_01196 2.72e-62 - - - - - - - -
PHOPOLEM_01197 4.17e-49 - - - - - - - -
PHOPOLEM_01198 8.4e-33 - - - - - - - -
PHOPOLEM_01201 4.12e-90 - - - S - - - Pfam:CtkA_N
PHOPOLEM_01203 8.29e-92 - - - - ko:K03646 - ko00000,ko02000 -
PHOPOLEM_01204 7.38e-89 - - - - ko:K03646 - ko00000,ko02000 -
PHOPOLEM_01205 0.0 - - - D - - - Cell surface antigen C-terminus
PHOPOLEM_01206 6.7e-49 - - - M - - - domain protein
PHOPOLEM_01207 1.05e-14 - - - S - - - Leucine rich repeats (6 copies)
PHOPOLEM_01208 2.97e-87 - 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
PHOPOLEM_01209 2.73e-25 - - - D - - - nuclear chromosome segregation
PHOPOLEM_01211 2.17e-58 - - - S - - - Helix-turn-helix domain
PHOPOLEM_01212 3.01e-87 - - - S - - - PIN domain
PHOPOLEM_01215 7.17e-317 - - - U - - - Type IV secretory pathway, VirB4
PHOPOLEM_01216 0.0 - - - U - - - TraM recognition site of TraD and TraG
PHOPOLEM_01221 0.0 - - - V - - - N-6 DNA Methylase
PHOPOLEM_01222 9.35e-106 - - - L - - - Resolvase, N terminal domain
PHOPOLEM_01224 3.07e-77 - - - V - - - Psort location Cytoplasmic, score
PHOPOLEM_01225 6.08e-49 - - - - - - - -
PHOPOLEM_01227 7.53e-42 - - - - - - - -
PHOPOLEM_01229 3.18e-108 - - - - - - - -
PHOPOLEM_01231 0.0 - - - KL - - - Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
PHOPOLEM_01234 5.9e-22 - - - - - - - -
PHOPOLEM_01237 2.81e-243 - 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 DNA topoisomerase
PHOPOLEM_01238 7.61e-96 - - - D - - - nucleotidyltransferase activity
PHOPOLEM_01239 2.52e-48 - - - S ko:K19158 - ko00000,ko01000,ko02048 YoeB-like toxin of bacterial type II toxin-antitoxin system
PHOPOLEM_01240 1.72e-40 - - - D ko:K19159 - ko00000,ko02048 Antitoxin component of a toxin-antitoxin (TA) module
PHOPOLEM_01241 4.01e-43 - - - - - - - -
PHOPOLEM_01242 0.0 - - - L - - - DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
PHOPOLEM_01244 7.03e-80 - - - - - - - -
PHOPOLEM_01245 1.4e-73 - - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 single-stranded DNA binding
PHOPOLEM_01247 3.3e-127 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Exonuclease, DNA polymerase III, epsilon subunit family
PHOPOLEM_01248 5.88e-125 - - - S - - - Protein of unknown function (DUF2786)
PHOPOLEM_01255 1.08e-49 - - - DJ ko:K06218 - ko00000,ko02048 Addiction module toxin, RelE StbE family
PHOPOLEM_01256 3.07e-36 - - - S - - - Antitoxin component of a toxin-antitoxin (TA) module
PHOPOLEM_01260 4.29e-28 - - - - - - - -
PHOPOLEM_01261 1.69e-61 - - - S - - - Phage derived protein Gp49-like (DUF891)
PHOPOLEM_01262 1.94e-42 - - - K - - - Helix-turn-helix domain
PHOPOLEM_01264 7.36e-31 - - - S - - - Domain of unknown function (DUF3846)
PHOPOLEM_01266 0.00011 - - - K - - - Psort location Cytoplasmic, score
PHOPOLEM_01267 5.64e-178 - 3.6.4.12 - F ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 RecQ zinc-binding
PHOPOLEM_01269 8.18e-13 - - - - - - - -
PHOPOLEM_01279 1.46e-25 - - - - - - - -
PHOPOLEM_01280 2.96e-226 intA - - L - - - Phage integrase family
PHOPOLEM_01282 9.71e-72 - - - S - - - Helix-turn-helix domain
PHOPOLEM_01287 3.52e-88 ydhQ 2.7.11.1 - MU ko:K12132 - ko00000,ko01000,ko01001 cell adhesion
PHOPOLEM_01292 1.67e-241 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PHOPOLEM_01293 3.16e-180 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PHOPOLEM_01294 5.54e-131 - - - - - - - -
PHOPOLEM_01295 5.01e-311 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PHOPOLEM_01296 0.0 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PHOPOLEM_01297 0.0 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase N terminus
PHOPOLEM_01298 4.16e-297 - - - EGP - - - Transporter major facilitator family protein
PHOPOLEM_01299 3.5e-137 - - - E - - - haloacid dehalogenase-like hydrolase
PHOPOLEM_01300 1.96e-222 - - - G - - - Fic/DOC family
PHOPOLEM_01301 1.03e-185 - - - - - - - -
PHOPOLEM_01302 9.96e-209 - 1.1.1.127 - IQ ko:K00065 ko00040,map00040 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
PHOPOLEM_01303 0.0 - - - - - - - -
PHOPOLEM_01304 2.22e-120 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Redoxin
PHOPOLEM_01305 0.0 - - - L - - - Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
PHOPOLEM_01306 0.0 - - - L - - - Z1 domain
PHOPOLEM_01307 9.13e-202 - - - S - - - Putative PD-(D/E)XK family member, (DUF4420)
PHOPOLEM_01308 0.0 - - - S - - - AIPR protein
PHOPOLEM_01309 0.0 - 2.1.1.37 - H ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 C-5 cytosine-specific DNA methylase
PHOPOLEM_01310 0.0 ftsK - - L ko:K03466,ko:K07474,ko:K19175 - ko00000,ko02048,ko03036 PIF1-like helicase
PHOPOLEM_01312 2.99e-122 - - - S ko:K07005 - ko00000 Pyridoxamine 5'-phosphate oxidase
PHOPOLEM_01313 0.0 - - - S - - - Histidine phosphatase superfamily (branch 2)
PHOPOLEM_01314 9.32e-59 - - - L - - - transposition
PHOPOLEM_01315 6.03e-30 - - - C - - - Acetamidase/Formamidase family
PHOPOLEM_01316 5.29e-78 - - - K ko:K07979 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
PHOPOLEM_01317 3.94e-221 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
PHOPOLEM_01318 9.27e-159 - - - S - - - ABC-2 family transporter protein
PHOPOLEM_01319 5.07e-158 - - - S - - - Haloacid dehalogenase-like hydrolase
PHOPOLEM_01320 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
PHOPOLEM_01321 4.06e-241 nadK 2.7.1.23 - H ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PHOPOLEM_01322 0.0 trkH - - P ko:K03498 - ko00000,ko02000 Cation transport protein
PHOPOLEM_01323 5.1e-150 trkA - - P ko:K03499 - ko00000,ko02000 TrkA-N domain
PHOPOLEM_01324 7.95e-172 tlyA 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
PHOPOLEM_01325 6.51e-247 - - - G - - - Haloacid dehalogenase-like hydrolase
PHOPOLEM_01326 8.59e-217 - - - L - - - Tetratricopeptide repeat
PHOPOLEM_01327 1.91e-316 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PHOPOLEM_01328 0.0 - - - S - - - Protein of unknown function (DUF975)
PHOPOLEM_01329 1.01e-181 - - - S - - - Putative ABC-transporter type IV
PHOPOLEM_01330 4.08e-123 - - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
PHOPOLEM_01331 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
PHOPOLEM_01332 4.33e-303 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
PHOPOLEM_01333 5.46e-109 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
PHOPOLEM_01334 9.86e-237 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
PHOPOLEM_01335 5.56e-305 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class-III
PHOPOLEM_01336 5.02e-228 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
PHOPOLEM_01337 8.39e-261 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
PHOPOLEM_01338 1.16e-263 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
PHOPOLEM_01339 7.69e-148 - - - - - - - -
PHOPOLEM_01340 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Phenylalanyl-tRNA synthetase beta
PHOPOLEM_01341 9.1e-261 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PHOPOLEM_01343 5.91e-14 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
PHOPOLEM_01344 3.02e-124 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Possible lysine decarboxylase
PHOPOLEM_01345 2.06e-25 - - - - - - - -
PHOPOLEM_01347 2.76e-15 - - - L ko:K07451 - ko00000,ko01000,ko02048 HNH endonuclease
PHOPOLEM_01348 2.27e-146 - - - L - - - Uracil DNA glycosylase superfamily
PHOPOLEM_01349 7.18e-20 - - - V - - - Type II restriction enzyme, methylase subunits
PHOPOLEM_01350 1.27e-34 - - - L - - - Phage integrase, N-terminal SAM-like domain
PHOPOLEM_01351 5.67e-233 - - - L - - - Phage integrase, N-terminal SAM-like domain
PHOPOLEM_01352 9.33e-12 - - - - - - - -
PHOPOLEM_01353 9.89e-79 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
PHOPOLEM_01354 3.96e-268 - - - S - - - Domain of unknown function (DUF4838)
PHOPOLEM_01355 8.82e-223 - - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PHOPOLEM_01356 1.71e-129 - - - G ko:K17329 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
PHOPOLEM_01357 9.3e-105 - - - U ko:K17330 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PHOPOLEM_01358 1.76e-109 - - - U ko:K17331 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PHOPOLEM_01359 6.01e-81 - - - GK - - - ROK family
PHOPOLEM_01361 5.79e-35 - - - - - - - -
PHOPOLEM_01362 5.63e-30 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix domain
PHOPOLEM_01364 2.89e-37 - - - - - - - -
PHOPOLEM_01365 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
PHOPOLEM_01366 5.03e-183 - - - S - - - Domain of unknown function (DUF4191)
PHOPOLEM_01367 0.0 lpdA 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PHOPOLEM_01368 6.58e-126 - - - S - - - Protein of unknown function (DUF3043)
PHOPOLEM_01369 0.0 argE - - E - - - Peptidase dimerisation domain
PHOPOLEM_01370 3.54e-193 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
PHOPOLEM_01371 0.0 ykoD - - P ko:K16785,ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
PHOPOLEM_01372 1.11e-140 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
PHOPOLEM_01373 1.09e-265 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
PHOPOLEM_01374 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PHOPOLEM_01375 0.0 - - - S - - - Tetratricopeptide repeat
PHOPOLEM_01376 0.0 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
PHOPOLEM_01377 0.0 - 2.8.2.22 - S ko:K01023 - ko00000,ko01000 Arylsulfotransferase Ig-like domain
PHOPOLEM_01378 3.66e-185 - - - P ko:K16784 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
PHOPOLEM_01379 2.89e-281 - - - E - - - Aminotransferase class I and II
PHOPOLEM_01380 3.28e-181 ppgK 2.7.1.2, 2.7.1.63 - GK ko:K00845,ko:K00886 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
PHOPOLEM_01381 9.03e-258 - - - S - - - Glycosyltransferase, group 2 family protein
PHOPOLEM_01382 5.48e-189 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
PHOPOLEM_01383 3.73e-63 - - - J ko:K07574 - ko00000,ko03009 CRS1_YhbY
PHOPOLEM_01384 0.0 - - - GP ko:K16785,ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
PHOPOLEM_01385 2.78e-139 - - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
PHOPOLEM_01386 0.0 - - - KL - - - Psort location Cytoplasmic, score 8.87
PHOPOLEM_01387 1.32e-52 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 homocysteine catabolic process
PHOPOLEM_01388 2.77e-141 - - - U ko:K10716 - ko00000,ko02000 Ion channel
PHOPOLEM_01389 1.11e-237 - - - EH - - - D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
PHOPOLEM_01390 6.33e-109 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
PHOPOLEM_01391 1.79e-159 - - - S - - - alpha beta
PHOPOLEM_01392 1.13e-17 - - - - - - - -
PHOPOLEM_01393 0.0 - - - L ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
PHOPOLEM_01394 3.47e-163 - - - K - - - Helix-turn-helix domain protein
PHOPOLEM_01396 1.04e-25 - - - - - - - -
PHOPOLEM_01397 6.65e-215 - - - - - - - -
PHOPOLEM_01398 6.65e-188 - - - S - - - phosphoesterase or phosphohydrolase
PHOPOLEM_01399 4.79e-104 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Cupin domain
PHOPOLEM_01400 8.51e-14 - 1.1.1.91 - C ko:K05882 - ko00000,ko01000 Aldo/keto reductase family
PHOPOLEM_01401 5.04e-168 - - - E - - - Psort location Cytoplasmic, score 8.87
PHOPOLEM_01402 1.26e-166 - - - S - - - DUF218 domain
PHOPOLEM_01403 2.43e-301 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
PHOPOLEM_01404 9.85e-299 rnd 3.1.13.5 - J ko:K03684 - ko00000,ko01000,ko03016 3'-5' exonuclease
PHOPOLEM_01405 1.34e-101 - - - S - - - Protein of unknown function (DUF3000)
PHOPOLEM_01406 2.05e-209 pflA 1.97.1.4 - C ko:K04069 - ko00000,ko01000 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PHOPOLEM_01407 0.0 pflB 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 Pyruvate formate lyase-like
PHOPOLEM_01408 1.28e-41 - - - - - - - -
PHOPOLEM_01409 0.0 nadE 6.3.5.1 - H ko:K01950 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PHOPOLEM_01410 1.58e-286 - - - S - - - Peptidase dimerisation domain
PHOPOLEM_01411 1.92e-199 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
PHOPOLEM_01412 5.21e-191 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 NLPA lipoprotein
PHOPOLEM_01413 2.39e-187 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PHOPOLEM_01414 6.47e-144 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PHOPOLEM_01415 1.52e-98 - - - - - - - -
PHOPOLEM_01417 3.35e-160 - - - V - - - Abi-like protein
PHOPOLEM_01418 1.64e-25 - - - V - - - Abi-like protein
PHOPOLEM_01419 0.0 - - - S ko:K09704 - ko00000 Metal-independent alpha-mannosidase (GH125)
PHOPOLEM_01420 9.53e-305 - - - G - - - N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
PHOPOLEM_01421 1.69e-258 - - - K - - - helix_turn _helix lactose operon repressor
PHOPOLEM_01422 9.79e-107 - - - G - - - Glycosyl hydrolase family 85
PHOPOLEM_01423 1.34e-162 - - - G - - - Glycosyl hydrolase family 85
PHOPOLEM_01424 7.14e-232 - - - G - - - Glycosyl hydrolase family 85
PHOPOLEM_01425 1.74e-18 - - - G - - - Glycosyl hydrolase family 85
PHOPOLEM_01426 8.76e-218 - - - G - - - Glycosyl hydrolase, family 20, catalytic domain
PHOPOLEM_01427 0.0 - 3.2.1.21 GH3 G ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Glycosyl hydrolase family 3 C-terminal domain
PHOPOLEM_01428 0.0 - - - G - - - Belongs to the glycosyl hydrolase 5 (cellulase A) family
PHOPOLEM_01429 5.5e-201 - - - G ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PHOPOLEM_01430 4.03e-216 - - - G ko:K02025,ko:K17330 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PHOPOLEM_01431 0.0 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
PHOPOLEM_01432 0.0 - 3.2.1.24 GH38 G ko:K01191 ko00511,map00511 ko00000,ko00001,ko01000,ko04131 Alpha mannosidase, middle domain
PHOPOLEM_01433 0.0 - 3.2.1.24 GH38 G ko:K01191 ko00511,map00511 ko00000,ko00001,ko01000,ko04131 Alpha mannosidase, middle domain
PHOPOLEM_01434 5.59e-109 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
PHOPOLEM_01435 1.2e-105 - - - S - - - von Willebrand factor (vWF) type A domain
PHOPOLEM_01436 6.72e-31 lppD - - S - - - Appr-1'-p processing enzyme
PHOPOLEM_01437 2.27e-19 intA - - L - - - Phage integrase family
PHOPOLEM_01439 9.71e-54 - - - - - - - -
PHOPOLEM_01440 6.89e-164 - - - S - - - Fic/DOC family
PHOPOLEM_01441 2.14e-260 - - - S - - - HipA-like C-terminal domain
PHOPOLEM_01443 3.61e-96 - - - - - - - -
PHOPOLEM_01444 3.52e-300 intA - - L - - - Phage integrase family
PHOPOLEM_01446 1.77e-95 - - - S - - - EcsC protein family
PHOPOLEM_01448 5.28e-48 - - - L - - - Restriction endonuclease XhoI
PHOPOLEM_01449 4.68e-129 - - - L - - - DNA restriction-modification system
PHOPOLEM_01450 5.52e-65 - - - - - - - -
PHOPOLEM_01451 5.45e-79 - - - - - - - -
PHOPOLEM_01452 6.61e-85 - - - - - - - -
PHOPOLEM_01453 0.0 - 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 DNA topoisomerase
PHOPOLEM_01454 2.51e-78 - - - - - - - -
PHOPOLEM_01455 9.14e-38 - - - - - - - -
PHOPOLEM_01457 5.28e-59 - - - S - - - Domain of unknown function (DUF4160)
PHOPOLEM_01458 5.88e-55 - - - K - - - Protein of unknown function (DUF2442)
PHOPOLEM_01459 3.58e-56 - - - S - - - Bacterial mobilisation protein (MobC)
PHOPOLEM_01460 0.0 - - - U - - - Relaxase/Mobilisation nuclease domain
PHOPOLEM_01461 2.07e-199 - - - S - - - Protein of unknown function (DUF3801)
PHOPOLEM_01462 0.0 - - - - - - - -
PHOPOLEM_01463 0.0 - - - KL - - - Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
PHOPOLEM_01464 1.57e-57 - - - - - - - -
PHOPOLEM_01465 5.14e-41 - - - - - - - -
PHOPOLEM_01466 0.0 - - - U ko:K03205 ko03070,map03070 ko00000,ko00001,ko00002,ko02044 Type IV secretory system Conjugative DNA transfer
PHOPOLEM_01470 9.59e-122 - - - K - - - Helix-turn-helix domain protein
PHOPOLEM_01472 2.45e-79 - - - - ko:K03646 - ko00000,ko02000 -
PHOPOLEM_01474 6.63e-178 - - - M - - - CHAP domain
PHOPOLEM_01476 0.0 - - - U - - - type IV secretory pathway VirB4
PHOPOLEM_01477 1.4e-80 - - - S - - - PrgI family protein
PHOPOLEM_01478 3.85e-177 - - - - - - - -
PHOPOLEM_01479 2.26e-35 - - - - - - - -
PHOPOLEM_01480 4.47e-172 - - - - - - - -
PHOPOLEM_01481 6.82e-26 - - - M - - - Listeria-Bacteroides repeat domain (List_Bact_rpt)
PHOPOLEM_01485 9.63e-31 - - - - - - - -
PHOPOLEM_01486 1.54e-145 - - - D ko:K03496 - ko00000,ko03036,ko04812 AAA domain
PHOPOLEM_01487 7.91e-115 - - - S - - - Transcription factor WhiB
PHOPOLEM_01488 1e-56 - - - - - - - -
PHOPOLEM_01489 1.16e-262 - - - S - - - Helix-turn-helix domain
PHOPOLEM_01490 4.41e-19 - - - - - - - -
PHOPOLEM_01491 1.26e-34 - - - - - - - -
PHOPOLEM_01492 1.14e-149 - - - - - - - -
PHOPOLEM_01493 2.93e-60 - - - - - - - -
PHOPOLEM_01494 5.11e-183 ppiA 5.2.1.8 - G ko:K03767,ko:K03768 ko01503,ko04217,map01503,map04217 ko00000,ko00001,ko01000,ko03110,ko04147 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PHOPOLEM_01495 0.0 relA 2.7.6.5, 3.1.7.2 - KT ko:K00951,ko:K01139 ko00230,map00230 ko00000,ko00001,ko01000,ko03009 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PHOPOLEM_01496 5.02e-110 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
PHOPOLEM_01497 8.5e-63 - - - S - - - Domain of unknown function (DUF4193)
PHOPOLEM_01498 1.37e-228 - - - S - - - Protein of unknown function (DUF3071)
PHOPOLEM_01499 7.19e-300 - - - S - - - Type I phosphodiesterase / nucleotide pyrophosphatase
PHOPOLEM_01500 0.0 gyrA2 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 DNA topoisomerase (ATP-hydrolyzing)
PHOPOLEM_01501 0.0 lhr - - L ko:K03724 - ko00000,ko01000,ko03400 DEAD DEAH box helicase
PHOPOLEM_01502 6.21e-43 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
PHOPOLEM_01503 2.16e-100 - - - S - - - Protein of unknown function (DUF2975)
PHOPOLEM_01504 2.69e-310 - - - T - - - Domain of unknown function (DUF4173)
PHOPOLEM_01505 1.04e-287 - - - G - - - Major Facilitator Superfamily
PHOPOLEM_01506 0.0 gyrB2 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 DNA topoisomerase (ATP-hydrolyzing)
PHOPOLEM_01507 3.32e-226 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
PHOPOLEM_01508 2.58e-152 - - - - - - - -
PHOPOLEM_01509 3.65e-251 idsA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13787 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
PHOPOLEM_01510 0.0 pknL 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 PASTA
PHOPOLEM_01511 8.73e-171 plsC2 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Phosphate acyltransferases
PHOPOLEM_01512 4.49e-129 - - - - - - - -
PHOPOLEM_01513 3.23e-247 trpD 2.4.2.18 - F ko:K00766 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PHOPOLEM_01514 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
PHOPOLEM_01515 5.45e-153 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PHOPOLEM_01516 4.3e-158 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
PHOPOLEM_01517 4.97e-271 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PHOPOLEM_01518 8.27e-60 - - - S - - - Protein of unknown function (DUF3046)
PHOPOLEM_01519 3.83e-104 - - - K - - - Helix-turn-helix XRE-family like proteins
PHOPOLEM_01520 7.04e-127 cinA 3.5.1.42 - S ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
PHOPOLEM_01521 1.75e-157 pgsA 2.7.8.41, 2.7.8.5 - I ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PHOPOLEM_01522 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 FtsK SpoIIIE family protein
PHOPOLEM_01523 1.6e-246 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PHOPOLEM_01524 0.0 miaB 2.8.4.3 - H ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PHOPOLEM_01525 6.96e-201 ywaC 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 Region found in RelA / SpoT proteins
PHOPOLEM_01526 6.83e-228 - - - EG - - - EamA-like transporter family
PHOPOLEM_01527 4.11e-170 - - - S ko:K06890 - ko00000 Belongs to the BI1 family
PHOPOLEM_01528 1.64e-146 - - - S - - - Domain of unknown function (DUF5067)
PHOPOLEM_01529 6.13e-79 - - - T - - - Histidine kinase
PHOPOLEM_01530 2.47e-191 - - - T - - - Histidine kinase
PHOPOLEM_01531 8.7e-166 - - - K - - - helix_turn_helix, Lux Regulon
PHOPOLEM_01532 0.0 - - - S - - - Protein of unknown function DUF262
PHOPOLEM_01533 3.27e-150 - - - K - - - helix_turn_helix, Lux Regulon
PHOPOLEM_01534 2.58e-311 - - - T - - - Histidine kinase
PHOPOLEM_01535 1.72e-242 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
PHOPOLEM_01536 1.48e-287 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
PHOPOLEM_01537 3.96e-292 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
PHOPOLEM_01538 1.35e-266 - - - K - - - helix_turn_helix, arabinose operon control protein
PHOPOLEM_01539 4.5e-150 - 2.3.1.18, 2.3.1.79 - S ko:K00633,ko:K00661 - ko00000,ko01000 Bacterial transferase hexapeptide repeat protein
PHOPOLEM_01540 0.0 - - - V - - - Psort location CytoplasmicMembrane, score 9.99
PHOPOLEM_01541 0.0 acnA 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
PHOPOLEM_01542 0.0 ctpE - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
PHOPOLEM_01543 3.04e-119 - - - - - - - -
PHOPOLEM_01544 6.24e-306 rumA 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PHOPOLEM_01545 7.07e-168 - - - S - - - Protein of unknown function (DUF3159)
PHOPOLEM_01546 4.1e-191 - - - S - - - Protein of unknown function (DUF3710)
PHOPOLEM_01547 6.53e-217 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease/Exonuclease/phosphatase family
PHOPOLEM_01548 0.0 - - - EP ko:K02031,ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Oligopeptide/dipeptide transporter, C-terminal region
PHOPOLEM_01549 6.03e-222 dppC - - EP ko:K02034,ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 N-terminal TM domain of oligopeptide transport permease C
PHOPOLEM_01550 2.57e-200 dppB - - EP ko:K02033,ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PHOPOLEM_01551 0.0 dppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, family 5
PHOPOLEM_01552 3.23e-219 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family. XerC subfamily
PHOPOLEM_01553 2.11e-46 - - - - - - - -
PHOPOLEM_01554 2.11e-250 tyrA 1.3.1.12 - E ko:K00210,ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydrogenase
PHOPOLEM_01555 1.86e-243 pheA 4.2.1.51, 5.4.99.5 - E ko:K04518,ko:K14170 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
PHOPOLEM_01556 2.47e-136 - - - - - - - -
PHOPOLEM_01557 0.0 typA - - T ko:K06207 - ko00000 Elongation factor G C-terminus
PHOPOLEM_01558 0.0 nanT - - U ko:K03290,ko:K08178,ko:K08369 - ko00000,ko02000 Sugar (and other) transporter
PHOPOLEM_01559 6.41e-193 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NUDIX hydrolase
PHOPOLEM_01560 8.39e-196 soj - - D ko:K03496 - ko00000,ko03036,ko04812 CobQ CobB MinD ParA nucleotide binding domain protein
PHOPOLEM_01561 3.01e-224 xerD - - D ko:K03733,ko:K04763 - ko00000,ko03036 recombinase XerD
PHOPOLEM_01562 7.76e-81 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PHOPOLEM_01563 3.31e-35 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L35
PHOPOLEM_01564 1.86e-139 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PHOPOLEM_01565 2.3e-142 - 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Thiamin pyrophosphokinase, vitamin B1 binding domain
PHOPOLEM_01566 4.82e-254 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
PHOPOLEM_01567 8.17e-114 ybaK - - J ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PHOPOLEM_01568 1.88e-219 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
PHOPOLEM_01569 9.14e-239 - 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
PHOPOLEM_01570 1.03e-48 - - - - - - - -
PHOPOLEM_01571 6.43e-126 sigH - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
PHOPOLEM_01572 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PHOPOLEM_01573 3.19e-238 - - - V - - - Acetyltransferase (GNAT) domain
PHOPOLEM_01574 0.0 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Mur ligase middle domain
PHOPOLEM_01575 0.0 pepP 3.4.11.9 - E ko:K01262 - ko00000,ko01000,ko01002 Aminopeptidase P, N-terminal domain
PHOPOLEM_01576 5.09e-124 - - - F - - - NUDIX domain
PHOPOLEM_01577 0.0 - - - P ko:K02031,ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
PHOPOLEM_01578 5.18e-255 dppC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PHOPOLEM_01579 5.48e-241 dppB - - EP ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PHOPOLEM_01580 0.0 - - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
PHOPOLEM_01581 6.36e-277 - 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
PHOPOLEM_01582 1.93e-211 - 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
PHOPOLEM_01583 4.82e-277 - - - S ko:K09704 - ko00000 Metal-independent alpha-mannosidase (GH125)
PHOPOLEM_01585 6.6e-21 - - - G - - - N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
PHOPOLEM_01586 1.01e-263 - - - G - - - N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
PHOPOLEM_01587 3.4e-182 ftsQ - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein FtsQ
PHOPOLEM_01588 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
PHOPOLEM_01589 1.23e-273 murG 2.4.1.227, 6.3.2.8 GT28 M ko:K01924,ko:K02563 ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PHOPOLEM_01590 4.97e-259 ftsW 2.4.1.227 GT28 D ko:K02563,ko:K03588 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011,ko02000,ko03036 Belongs to the SEDS family
PHOPOLEM_01591 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PHOPOLEM_01592 1.38e-251 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PHOPOLEM_01593 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
PHOPOLEM_01594 1.19e-197 - - - M - - - Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PHOPOLEM_01595 0.0 ftsI 3.4.16.4 - M ko:K03587 ko00550,ko01501,map00550,map01501 ko00000,ko00001,ko01000,ko01011,ko03036 Penicillin-binding protein, transpeptidase domain protein
PHOPOLEM_01596 7.27e-82 - - - D - - - Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
PHOPOLEM_01597 1.41e-242 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
PHOPOLEM_01598 9.51e-119 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
PHOPOLEM_01599 0.0 - - - L - - - DNA helicase
PHOPOLEM_01600 9.75e-276 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
PHOPOLEM_01601 1.01e-109 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PHOPOLEM_01602 8.85e-72 - - - M - - - Lysin motif
PHOPOLEM_01603 6.88e-170 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PHOPOLEM_01604 4.75e-192 czcD - - P ko:K16264 - ko00000,ko02000 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PHOPOLEM_01605 3.25e-225 ldh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
PHOPOLEM_01606 0.0 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PHOPOLEM_01607 1.62e-145 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase (PrmA)
PHOPOLEM_01608 0.0 hrpA 3.6.4.13 - L ko:K03578 - ko00000,ko01000 Helicase associated domain (HA2) Add an annotation
PHOPOLEM_01609 3.19e-242 - - - - - - - -
PHOPOLEM_01610 4.63e-234 - - - V - - - N-Acetylmuramoyl-L-alanine amidase
PHOPOLEM_01611 5.6e-129 - - - - - - - -
PHOPOLEM_01612 2.51e-152 - - - V ko:K02003,ko:K09810 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
PHOPOLEM_01613 6.36e-280 - - - EGP ko:K18567,ko:K19577 - ko00000,ko02000 Major Facilitator Superfamily
PHOPOLEM_01614 1.66e-185 - - - M - - - Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
PHOPOLEM_01615 6.42e-309 - - - S - - - Domain of unknown function (DUF5067)
PHOPOLEM_01616 0.0 glnA2 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
PHOPOLEM_01617 2.38e-167 hisA 5.3.1.16, 5.3.1.24 - E ko:K01814,ko:K01817 ko00340,ko00400,ko01100,ko01110,ko01130,ko01230,map00340,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Histidine biosynthesis protein
PHOPOLEM_01618 1.77e-156 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
PHOPOLEM_01619 9.72e-162 - - - - - - - -
PHOPOLEM_01620 4.56e-142 hisB 3.1.3.15, 4.2.1.19 - E ko:K01089,ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Imidazoleglycerol-phosphate dehydratase
PHOPOLEM_01621 5.53e-287 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PHOPOLEM_01622 0.0 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PHOPOLEM_01623 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III alpha subunit
PHOPOLEM_01624 3.52e-225 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
PHOPOLEM_01625 2.28e-120 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PHOPOLEM_01626 2.23e-65 - - - V - - - DivIVA protein
PHOPOLEM_01627 9.14e-55 - - - S ko:K02221 - ko00000,ko02044 YGGT family
PHOPOLEM_01628 5.84e-105 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
PHOPOLEM_01629 4.66e-279 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PHOPOLEM_01630 9.23e-311 dus - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PHOPOLEM_01631 0.0 glyQS 6.1.1.14 - J ko:K01880 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of glycine to tRNA(Gly)
PHOPOLEM_01632 1.34e-197 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
PHOPOLEM_01633 4.71e-172 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 - H ko:K03147,ko:K14153 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
PHOPOLEM_01634 2.05e-192 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
PHOPOLEM_01635 3.37e-79 - - - S - - - Thiamine-binding protein
PHOPOLEM_01636 1.12e-247 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
PHOPOLEM_01637 3.92e-306 lacY - - P ko:K02532 - ko00000,ko02000 LacY proton/sugar symporter
PHOPOLEM_01638 0.0 fosC 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
PHOPOLEM_01639 1.3e-180 - - - P - - - Binding-protein-dependent transport system inner membrane component
PHOPOLEM_01640 4.99e-262 - - - P - - - NMT1/THI5 like
PHOPOLEM_01641 1.33e-293 - - - F - - - nucleoside hydrolase
PHOPOLEM_01642 9.88e-196 uppS 2.5.1.31, 2.5.1.86, 2.5.1.88 - H ko:K00806,ko:K14215,ko:K21273 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PHOPOLEM_01643 9.76e-172 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
PHOPOLEM_01644 0.0 - - - I - - - acetylesterase activity
PHOPOLEM_01645 5.54e-286 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
PHOPOLEM_01646 6.59e-275 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
PHOPOLEM_01647 0.0 - - - NU - - - Tfp pilus assembly protein FimV
PHOPOLEM_01649 3.68e-97 - - - S - - - Protein of unknown function (DUF3052)
PHOPOLEM_01650 9.98e-197 sdrC - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
PHOPOLEM_01651 0.0 - - - S - - - Zincin-like metallopeptidase
PHOPOLEM_01652 0.0 uvrD2 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
PHOPOLEM_01653 0.0 mphA - - S - - - Aminoglycoside phosphotransferase
PHOPOLEM_01654 4.61e-44 - - - S - - - Protein of unknown function (DUF3107)
PHOPOLEM_01655 1.67e-221 PPA1328 3.1.3.97, 3.1.4.57 - S ko:K07053,ko:K20859 ko00440,map00440 ko00000,ko00001,ko01000 DNA polymerase alpha chain like domain
PHOPOLEM_01656 6.1e-151 - - - S - - - Vitamin K epoxide reductase
PHOPOLEM_01657 2.98e-215 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
PHOPOLEM_01658 2.16e-186 murI 5.1.1.3 - M ko:K01776 ko00471,ko01100,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
PHOPOLEM_01659 1.06e-29 - - - S ko:K07001 - ko00000 lipid catabolic process
PHOPOLEM_01660 0.0 dppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, family 5
PHOPOLEM_01661 5.22e-227 iaaA 3.4.19.5 - E ko:K13051 - ko00000,ko01000,ko01002 Asparaginase
PHOPOLEM_01662 7.07e-201 - - - S - - - Patatin-like phospholipase
PHOPOLEM_01663 2.52e-238 - - - K - - - LysR substrate binding domain protein
PHOPOLEM_01664 3.17e-305 - 4.4.1.8 - E ko:K00842,ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I II
PHOPOLEM_01665 2.09e-153 - - - S ko:K06999 - ko00000 Phospholipase/Carboxylesterase
PHOPOLEM_01666 2.23e-238 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
PHOPOLEM_01667 6e-154 casE - - S ko:K19126 - ko00000,ko02048 CRISPR_assoc
PHOPOLEM_01668 3.74e-145 casD - - S ko:K19125 - ko00000,ko02048 CRISPR-associated protein (Cas_Cas5)
PHOPOLEM_01669 1.11e-244 casC - - L ko:K19124 - ko00000,ko02048 CT1975-like protein
PHOPOLEM_01670 1.01e-142 casB - - S ko:K19046 - ko00000,ko02048 CRISPR-associated protein Cse2 (CRISPR_cse2)
PHOPOLEM_01671 0.0 casA - - L ko:K19123 - ko00000,ko02048 CRISPR system CASCADE complex protein CasA
PHOPOLEM_01672 0.0 cas3 - - L ko:K07012 - ko00000,ko01000,ko02048 DEAD-like helicases superfamily
PHOPOLEM_01673 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PHOPOLEM_01674 0.0 gph - - G ko:K16209 - ko00000,ko02000 Psort location CytoplasmicMembrane, score 10.00
PHOPOLEM_01675 6.91e-235 - - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
PHOPOLEM_01676 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter transmembrane region
PHOPOLEM_01677 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
PHOPOLEM_01678 1.65e-134 - - - K - - - MarR family
PHOPOLEM_01679 0.0 bglB 3.2.1.21 GH3 G ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Glycosyl hydrolase family 3 N-terminal domain protein
PHOPOLEM_01680 1.66e-136 - - - K - - - Bacterial regulatory proteins, tetR family
PHOPOLEM_01681 2.53e-254 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
PHOPOLEM_01682 3.47e-231 - - - G - - - Transporter major facilitator family protein
PHOPOLEM_01683 0.0 - 3.2.1.40 - E ko:K05989 - ko00000,ko01000 Bacterial alpha-L-rhamnosidase C-terminal domain
PHOPOLEM_01684 9.87e-273 - - - U ko:K06610 - ko00000,ko02000 Sugar (and other) transporter
PHOPOLEM_01685 1.02e-145 - - - K ko:K02529 - ko00000,ko03000 Periplasmic binding protein domain
PHOPOLEM_01686 3.9e-18 - - - K - - - helix_turn_helix, mercury resistance
PHOPOLEM_01687 1.38e-115 - - - K - - - helix_turn_helix, mercury resistance
PHOPOLEM_01688 5.7e-279 - - - U ko:K08168,ko:K18926 - ko00000,ko00002,ko01504,ko02000 Major Facilitator Superfamily
PHOPOLEM_01689 0.0 bgl2 3.2.1.21 GH3 G ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Fibronectin type III-like domain
PHOPOLEM_01690 8.04e-142 - - - K - - - Bacterial regulatory proteins, tetR family
PHOPOLEM_01691 1.73e-307 - 3.2.1.4, 3.2.1.58 GH5,GH9 G ko:K01179,ko:K01210 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 5 (cellulase A) family
PHOPOLEM_01692 0.0 - 3.2.1.37 GH43 G ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Glycosyl hydrolases family 43
PHOPOLEM_01693 1.75e-296 - 3.2.1.4, 3.2.1.58 GH5,GH9 G ko:K01179,ko:K01210 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 5 (cellulase A) family
PHOPOLEM_01694 1.73e-304 - - - G - - - Transporter major facilitator family protein
PHOPOLEM_01695 1.14e-135 - - - K - - - Bacterial regulatory proteins, tetR family
PHOPOLEM_01696 0.0 - 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 Beta-galactosidase trimerisation domain
PHOPOLEM_01697 5.5e-148 - - - K - - - Bacterial regulatory proteins, tetR family
PHOPOLEM_01698 0.0 egtA 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Glutamate-cysteine ligase family 2(GCS2)
PHOPOLEM_01699 0.0 hgdC - - I - - - CoA enzyme activase uncharacterised domain (DUF2229)
PHOPOLEM_01700 1.02e-199 - - - I - - - BadF/BadG/BcrA/BcrD ATPase family
PHOPOLEM_01701 3.18e-179 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PHOPOLEM_01702 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Anaerobic ribonucleoside-triphosphate reductase
PHOPOLEM_01703 7.39e-312 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PHOPOLEM_01704 8.4e-56 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PHOPOLEM_01706 1.38e-251 - - - S ko:K18353 ko01502,ko02020,map01502,map02020 ko00000,ko00001,ko00002,ko01504 Endonuclease/Exonuclease/phosphatase family
PHOPOLEM_01707 6.97e-129 tmp1 - - S - - - Domain of unknown function (DUF4391)
PHOPOLEM_01708 1.11e-214 ppx1 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 Ppx/GppA phosphatase family
PHOPOLEM_01709 1.23e-295 aspB 2.6.1.1, 2.6.1.2, 2.6.1.66 - E ko:K00812,ko:K08969,ko:K14260 ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class-V
PHOPOLEM_01710 1.83e-90 vsr - - L ko:K07458 - ko00000,ko01000,ko03400 May nick specific sequences that contain T G mispairs resulting from m5C-deamination
PHOPOLEM_01711 3.55e-237 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
PHOPOLEM_01712 0.0 - 3.6.4.12 - L ko:K03658 - ko00000,ko01000,ko03400 Psort location Cytoplasmic, score 8.87
PHOPOLEM_01713 1.49e-77 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
PHOPOLEM_01714 0.0 - - - KL - - - Domain of unknown function (DUF3427)
PHOPOLEM_01715 2.94e-99 - - - - - - - -
PHOPOLEM_01716 1.05e-97 - - - S - - - Bacterial PH domain
PHOPOLEM_01717 2.77e-312 - - - S - - - zinc finger
PHOPOLEM_01718 0.0 - - - L - - - Psort location Cytoplasmic, score
PHOPOLEM_01719 3.3e-158 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
PHOPOLEM_01720 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PHOPOLEM_01721 0.0 pepN 3.4.11.2 - E ko:K01256,ko:K08776 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Peptidase family M1 domain
PHOPOLEM_01722 0.0 rnj - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PHOPOLEM_01723 2.29e-194 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PHOPOLEM_01724 0.0 - 3.6.3.4, 3.6.3.54 - P ko:K01533,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 E1-E2 ATPase
PHOPOLEM_01725 6.79e-52 csoR - - S ko:K21600 - ko00000,ko03000 Metal-sensitive transcriptional repressor
PHOPOLEM_01726 7.53e-170 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
PHOPOLEM_01727 4.01e-314 - - - G - - - Major Facilitator Superfamily
PHOPOLEM_01728 0.0 uvrD2 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Belongs to the helicase family. UvrD subfamily
PHOPOLEM_01729 0.0 - - - L - - - PD-(D/E)XK nuclease superfamily
PHOPOLEM_01731 0.0 pknK 2.7.11.1 - KLT ko:K12132 - ko00000,ko01000,ko01001 Protein tyrosine kinase
PHOPOLEM_01732 0.0 - - - S - - - Fibronectin type 3 domain
PHOPOLEM_01733 3.5e-306 - - - S ko:K03924 - ko00000,ko01000 ATPase family associated with various cellular activities (AAA)
PHOPOLEM_01734 1.1e-280 - - - S - - - Protein of unknown function DUF58
PHOPOLEM_01735 0.0 - - - E - - - Transglutaminase-like superfamily
PHOPOLEM_01736 1.21e-210 - 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 Sigma factor PP2C-like phosphatases
PHOPOLEM_01737 4.63e-150 - - - B - - - Belongs to the OprB family
PHOPOLEM_01738 5.79e-125 - - - T - - - Forkhead associated domain
PHOPOLEM_01739 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PHOPOLEM_01740 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PHOPOLEM_01741 1e-137 - - - - - - - -
PHOPOLEM_01742 8.97e-233 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 FES
PHOPOLEM_01743 2.24e-162 spoU 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
PHOPOLEM_01744 0.0 - - - S ko:K09157 - ko00000 UPF0210 protein
PHOPOLEM_01745 1.32e-57 - - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
PHOPOLEM_01746 5.3e-28 - - - U ko:K18926 - ko00000,ko00002,ko02000 Drug resistance MFS transporter, drug H antiporter-2 family
PHOPOLEM_01747 1.45e-297 galK 2.7.1.6, 2.7.7.12 - G ko:K00849,ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GHMP kinase family. GalK subfamily
PHOPOLEM_01748 9.99e-317 galT 2.7.7.12 - C ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 Galactose-1-phosphate uridyl transferase, N-terminal domain
PHOPOLEM_01749 1.13e-181 - - - K - - - DeoR C terminal sensor domain
PHOPOLEM_01750 1.41e-289 pyrD 1.3.5.2, 1.3.98.1 - F ko:K00226,ko:K00254 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
PHOPOLEM_01751 1.03e-279 namA - - C - - - NADH:flavin oxidoreductase / NADH oxidase family
PHOPOLEM_01752 0.0 pon1 - - M - - - Transglycosylase
PHOPOLEM_01753 3.53e-169 crp - - K ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 helix_turn_helix, cAMP Regulatory protein
PHOPOLEM_01754 8.63e-274 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Biotin/lipoate A/B protein ligase family
PHOPOLEM_01755 1.89e-128 - - - J - - - TM2 domain
PHOPOLEM_01756 3.92e-246 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
PHOPOLEM_01757 0.0 ptrB 3.4.21.83 - E ko:K01354 ko05142,ko05143,map05142,map05143 ko00000,ko00001,ko01000,ko01002 Peptidase, S9A B C family, catalytic domain protein
PHOPOLEM_01758 1.07e-301 - - - S - - - Uncharacterized conserved protein (DUF2183)
PHOPOLEM_01759 1.66e-92 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
PHOPOLEM_01760 1.03e-265 nudC 3.6.1.22 - L ko:K03426 ko00760,ko01100,ko04146,map00760,map01100,map04146 ko00000,ko00001,ko01000 NADH pyrophosphatase zinc ribbon domain
PHOPOLEM_01761 2.25e-206 - - - I - - - Alpha/beta hydrolase family
PHOPOLEM_01762 1.95e-147 - - - F - - - Domain of unknown function (DUF4916)
PHOPOLEM_01763 4.09e-80 trxA 1.8.1.9 - O ko:K00384,ko:K03671 ko00450,ko04621,ko05418,map00450,map04621,map05418 ko00000,ko00001,ko01000,ko03110 Belongs to the thioredoxin family
PHOPOLEM_01764 6.77e-224 - - - S ko:K21688 - ko00000 G5
PHOPOLEM_01765 9.58e-112 - - - - - - - -
PHOPOLEM_01766 1.83e-09 wcoI - - DM - - - Psort location CytoplasmicMembrane, score
PHOPOLEM_01767 2.57e-162 - - - M - - - Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
PHOPOLEM_01768 4.97e-144 - - - M - - - Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
PHOPOLEM_01769 0.0 - - - G - - - Belongs to the glycosyl hydrolase 31 family
PHOPOLEM_01770 5.43e-189 - - - P ko:K02026,ko:K10190 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PHOPOLEM_01771 2.74e-209 - - - P ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PHOPOLEM_01772 0.0 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
PHOPOLEM_01773 5.93e-237 - - - K - - - Psort location Cytoplasmic, score
PHOPOLEM_01774 2.6e-232 - - - K - - - helix_turn _helix lactose operon repressor
PHOPOLEM_01775 1.03e-282 - - - G ko:K02027,ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
PHOPOLEM_01776 4.31e-207 - - - G ko:K02025 - ko00000,ko00002,ko02000 PFAM binding-protein-dependent transport systems inner membrane component
PHOPOLEM_01777 1.28e-186 - - - G ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PHOPOLEM_01778 0.0 - 3.2.1.177 GH31 G ko:K01811 - ko00000,ko01000 Belongs to the glycosyl hydrolase 31 family
PHOPOLEM_01779 2.5e-77 yccF - - S - - - Inner membrane component domain
PHOPOLEM_01780 3.58e-267 - - - S - - - Psort location CytoplasmicMembrane, score 9.99
PHOPOLEM_01781 2.27e-18 - - - V - - - Abi-like protein
PHOPOLEM_01782 3.35e-35 - - - L - - - HTH-like domain
PHOPOLEM_01783 4.44e-115 - - - L - - - PFAM Integrase catalytic
PHOPOLEM_01784 7.96e-45 - - - S - - - enterobacterial common antigen metabolic process
PHOPOLEM_01787 5.16e-217 rfbA 2.7.7.24 - H ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
PHOPOLEM_01788 0.0 rfbD 1.1.1.133, 5.1.3.13 - M ko:K00067,ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
PHOPOLEM_01789 2.78e-252 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
PHOPOLEM_01790 3.03e-257 - - - S - - - Polysaccharide biosynthesis protein
PHOPOLEM_01791 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
PHOPOLEM_01792 8.13e-159 - 1.1.1.127 - IQ ko:K00065 ko00040,map00040 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
PHOPOLEM_01793 2.01e-213 - - - S ko:K16710 - ko00000 slime layer polysaccharide biosynthetic process
PHOPOLEM_01794 1.36e-152 - - - - - - - -
PHOPOLEM_01795 2.44e-166 - - - M - - - Glycosyl transferase family 2
PHOPOLEM_01796 9.14e-235 - - GT4 M ko:K12996 - ko00000,ko01000,ko01003,ko01005 Domain of unknown function (DUF1972)
PHOPOLEM_01797 8.09e-306 - - - M - - - Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
PHOPOLEM_01799 2.23e-138 - - - - - - - -
PHOPOLEM_01800 4.9e-37 - - - - - - - -
PHOPOLEM_01801 1.28e-254 wcoI - - DM - - - Psort location CytoplasmicMembrane, score
PHOPOLEM_01802 1.26e-281 - - - S - - - Protein of unknown function (DUF4012)
PHOPOLEM_01803 3.95e-112 etp 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Low molecular weight phosphatase family
PHOPOLEM_01804 8.63e-191 staP - - S ko:K18353 ko01502,ko02020,map01502,map02020 ko00000,ko00001,ko00002,ko01504 Endonuclease/Exonuclease/phosphatase family
PHOPOLEM_01805 4.19e-62 - - - - - - - -
PHOPOLEM_01806 0.0 - - - U - - - Drug resistance MFS transporter, drug H antiporter-2 family
PHOPOLEM_01808 6.77e-100 - - - T - - - Diguanylate cyclase (GGDEF) domain protein
PHOPOLEM_01809 3.99e-168 - - - L - - - Protein of unknown function (DUF1524)
PHOPOLEM_01810 1.54e-214 - - - S - - - Oxidoreductase, aldo keto reductase family protein
PHOPOLEM_01811 1.55e-308 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
PHOPOLEM_01812 1.38e-252 - - - K - - - helix_turn _helix lactose operon repressor
PHOPOLEM_01813 0.0 bga1 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.87
PHOPOLEM_01815 0.0 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
PHOPOLEM_01816 2.86e-162 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
PHOPOLEM_01817 6.62e-199 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
PHOPOLEM_01818 0.0 - - - V ko:K06147,ko:K06148,ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter transmembrane region
PHOPOLEM_01819 0.0 fadD 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme
PHOPOLEM_01820 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
PHOPOLEM_01821 1.1e-167 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Class II Aldolase and Adducin N-terminal domain
PHOPOLEM_01822 0.0 araB - - G - - - FGGY family of carbohydrate kinases, C-terminal domain
PHOPOLEM_01823 6.03e-270 - - - K - - - helix_turn _helix lactose operon repressor
PHOPOLEM_01824 0.0 maf - - DF ko:K06287 - ko00000 Maf-like protein
PHOPOLEM_01825 1.35e-240 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
PHOPOLEM_01826 3.73e-306 hom 1.1.1.3, 2.7.2.4 - E ko:K00003,ko:K12524 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Homoserine dehydrogenase
PHOPOLEM_01827 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
PHOPOLEM_01828 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
PHOPOLEM_01829 0.0 - - - E ko:K16235 - ko00000,ko02000 amino acid
PHOPOLEM_01830 2.8e-84 psp1 3.5.99.10 - J ko:K09022 - ko00000,ko01000 Endoribonuclease L-PSP
PHOPOLEM_01832 3.32e-155 - - - S - - - CYTH
PHOPOLEM_01833 2.52e-214 ybbN - - O ko:K05838 - ko00000,ko03110 Tetratricopeptide repeat
PHOPOLEM_01834 1.98e-232 - - - - - - - -
PHOPOLEM_01835 6.2e-266 - - - - - - - -
PHOPOLEM_01836 2.27e-192 - 5.2.1.8 - M ko:K01802 - ko00000,ko01000 FKBP-type peptidyl-prolyl cis-trans isomerase
PHOPOLEM_01837 1.32e-156 nucS - - L ko:K07503 - ko00000,ko01000 Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
PHOPOLEM_01838 9.92e-61 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
PHOPOLEM_01839 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PHOPOLEM_01840 5.5e-210 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PHOPOLEM_01841 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PHOPOLEM_01842 2.31e-191 atpH - - C ko:K02109,ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PHOPOLEM_01843 6.4e-93 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PHOPOLEM_01844 9.64e-42 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PHOPOLEM_01845 6.89e-190 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
PHOPOLEM_01846 1.2e-264 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PHOPOLEM_01848 1.01e-25 - - - K - - - BetR domain
PHOPOLEM_01853 8.71e-34 - - - - - - - -
PHOPOLEM_01854 1.22e-22 - - - - - - - -
PHOPOLEM_01857 6.16e-124 - - - L - - - HNH endonuclease
PHOPOLEM_01858 2.09e-51 - - - - - - - -
PHOPOLEM_01859 3.76e-296 - - - S - - - Terminase
PHOPOLEM_01860 4.49e-204 - - - S - - - Phage portal protein
PHOPOLEM_01861 2.65e-269 - - - S ko:K06904 - ko00000 Caudovirus prohead serine protease
PHOPOLEM_01862 9.02e-56 - - - - - - - -
PHOPOLEM_01863 3.96e-48 - - - - - - - -
PHOPOLEM_01864 4.33e-77 - - - - - - - -
PHOPOLEM_01865 2.99e-73 - - - - - - - -
PHOPOLEM_01866 4.45e-47 - - - - - - - -
PHOPOLEM_01868 1.21e-247 - - - NT - - - phage tail tape measure protein
PHOPOLEM_01871 5.19e-41 - - - S - - - Bacteriophage holin family
PHOPOLEM_01872 2.96e-80 - - - M - - - N-acetylmuramoyl-L-alanine amidase
PHOPOLEM_01873 2.03e-111 - - - L - - - Phage integrase family
PHOPOLEM_01874 0.0 frc 2.8.3.15, 2.8.3.16 - C ko:K07544,ko:K07749 ko00623,ko01100,ko01120,ko01220,map00623,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
PHOPOLEM_01875 1.17e-247 - - - S ko:K07088 - ko00000 Membrane transport protein
PHOPOLEM_01876 0.0 oxc 4.1.1.8 - EH ko:K01577 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Thiamine pyrophosphate enzyme, central domain
PHOPOLEM_01877 3.8e-224 - - - M - - - LPXTG-motif cell wall anchor domain protein
PHOPOLEM_01878 0.0 glgE 2.4.99.16 GH13 G ko:K16147 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
PHOPOLEM_01879 9.28e-118 ppa 3.6.1.1 - C ko:K01507 ko00190,map00190 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
PHOPOLEM_01880 5.21e-121 mntP - - P - - - Probably functions as a manganese efflux pump
PHOPOLEM_01881 1.09e-173 - - - - - - - -
PHOPOLEM_01882 1.1e-172 glnR - - KT - - - Transcriptional regulatory protein, C terminal
PHOPOLEM_01883 1.59e-156 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PHOPOLEM_01884 0.0 - - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
PHOPOLEM_01885 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
PHOPOLEM_01886 0.0 - - - S - - - domain protein
PHOPOLEM_01887 8.12e-90 tyrA 5.4.99.5 - E ko:K04092 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Chorismate mutase type II
PHOPOLEM_01888 6.29e-104 lrp_3 - - K ko:K03719 - ko00000,ko03000,ko03036 helix_turn_helix ASNC type
PHOPOLEM_01889 0.0 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
PHOPOLEM_01890 0.0 - - - H - - - Flavin containing amine oxidoreductase
PHOPOLEM_01891 1.43e-67 - - - S - - - Protein of unknown function (DUF2469)
PHOPOLEM_01892 1.4e-261 - - - J - - - Acetyltransferase (GNAT) domain
PHOPOLEM_01893 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PHOPOLEM_01894 0.0 gatA 6.3.5.6, 6.3.5.7 - F ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
PHOPOLEM_01895 5.47e-62 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PHOPOLEM_01896 2.17e-186 trmH 2.1.1.34 - J ko:K00556 - ko00000,ko01000,ko03016 RNA methyltransferase TrmH family
PHOPOLEM_01897 2.58e-147 pyrE1 - - F - - - Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PHOPOLEM_01898 0.0 - - - N - - - Glycosyl hydrolases family 43
PHOPOLEM_01899 0.0 - - - N - - - Bacterial Ig-like domain 2
PHOPOLEM_01900 4.86e-262 rmuC - - S ko:K09760 - ko00000 RmuC family
PHOPOLEM_01901 3.05e-185 - 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 Heavy metal translocating P-type atpase
PHOPOLEM_01902 0.0 clpB - - O ko:K03695,ko:K03696 ko01100,ko04213,map01100,map04213 ko00000,ko00001,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
PHOPOLEM_01903 4.27e-222 - - - Q - - - Fumarylacetoacetate (FAA) hydrolase family
PHOPOLEM_01904 7.14e-190 - - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
PHOPOLEM_01905 2.82e-105 - - - - - - - -
PHOPOLEM_01906 4.78e-262 gluQ 6.1.1.17 - J ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
PHOPOLEM_01907 1.29e-176 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
PHOPOLEM_01908 8.96e-39 - - - S - - - zinc-ribbon domain
PHOPOLEM_01911 5.47e-222 - - - T - - - Pfam Adenylate and Guanylate cyclase catalytic domain
PHOPOLEM_01912 0.0 - - - D - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
PHOPOLEM_01913 1.16e-92 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
PHOPOLEM_01914 3.05e-48 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PHOPOLEM_01915 6.98e-103 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
PHOPOLEM_01916 7.12e-62 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
PHOPOLEM_01917 3.76e-244 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PHOPOLEM_01918 1.37e-224 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PHOPOLEM_01919 0.0 - - - EGP ko:K08168 - ko00000,ko00002,ko01504,ko02000 Major Facilitator Superfamily
PHOPOLEM_01920 1.58e-215 iunH2 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Inosine-uridine preferring nucleoside hydrolase
PHOPOLEM_01921 3.02e-253 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
PHOPOLEM_01922 9.08e-83 - - - - - - - -
PHOPOLEM_01923 7.21e-24 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
PHOPOLEM_01924 5.21e-33 - - - S - - - Addiction module toxin, RelE StbE family
PHOPOLEM_01925 2.6e-258 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
PHOPOLEM_01926 0.0 - - - S ko:K07133 - ko00000 Domain of unknown function (DUF4143)
PHOPOLEM_01927 0.0 - - - M - - - Psort location CytoplasmicMembrane, score 9.26
PHOPOLEM_01928 2.3e-75 - - - S - - - oligosaccharyl transferase activity
PHOPOLEM_01929 5.06e-168 - - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 Glycosyl transferase family 2
PHOPOLEM_01930 2.62e-267 ugd 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 UDP binding domain
PHOPOLEM_01931 0.0 - - - M - - - Glycosyl transferase family 8
PHOPOLEM_01932 1.02e-175 tagG - - U ko:K01992 - ko00000,ko00002,ko02000 Transport permease protein
PHOPOLEM_01933 1.79e-216 - - - GM ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
PHOPOLEM_01934 8.1e-43 - - - M - - - Glycosyltransferase like family 2
PHOPOLEM_01935 0.0 - - - M - - - Glycosyl transferase family 8
PHOPOLEM_01936 3.32e-114 - - - - - - - -
PHOPOLEM_01939 9.01e-79 - 2.4.1.83 GT2 M ko:K00721 ko00510,ko01100,map00510,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyl transferase family 2
PHOPOLEM_01940 5.06e-107 - - - S - - - enterobacterial common antigen metabolic process
PHOPOLEM_01941 0.000172 strK 3.1.3.1, 3.1.3.39 - P ko:K01077,ko:K04342 ko00521,ko00730,ko00790,ko01100,ko01130,ko02020,map00521,map00730,map00790,map01100,map01130,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Alkaline phosphatase
PHOPOLEM_01942 2.03e-223 - - - M - - - Glycosyl hydrolases family 25
PHOPOLEM_01943 0.0 - - - S ko:K07133 - ko00000 AAA domain
PHOPOLEM_01944 2.4e-108 - - - - - - - -
PHOPOLEM_01946 5.26e-74 - 3.1.1.53 - E ko:K05970 - ko00000,ko01000 Carbohydrate esterase, sialic acid-specific acetylesterase
PHOPOLEM_01947 1.33e-284 - 3.1.1.53 - E ko:K05970 - ko00000,ko01000 Carbohydrate esterase, sialic acid-specific acetylesterase
PHOPOLEM_01948 3.1e-76 - - - - - - - -
PHOPOLEM_01950 8.02e-64 - - - EGP - - - Major Facilitator Superfamily
PHOPOLEM_01951 1.52e-37 - - - EGP - - - Major Facilitator Superfamily
PHOPOLEM_01952 5.97e-62 - - - EGP - - - Major Facilitator Superfamily
PHOPOLEM_01953 2.96e-42 yuxJ - - EGP - - - Major facilitator Superfamily

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)