ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
EPEFKAOO_00003 1.85e-76 - - - L ko:K07497 - ko00000 hmm pf00665
EPEFKAOO_00004 5.85e-225 hdhL 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
EPEFKAOO_00005 8.13e-198 mhpD - - Q ko:K02509 ko00350,ko01120,map00350,map01120 ko00000,ko00001,ko01000 hydratase
EPEFKAOO_00006 2.35e-305 - - - EGP - - - MFS transporter, metabolite H symporter (MHS) family protein
EPEFKAOO_00007 5.69e-280 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
EPEFKAOO_00008 3.39e-234 - - - D - - - nuclear chromosome segregation
EPEFKAOO_00009 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
EPEFKAOO_00010 6.49e-210 - - - S - - - Calcineurin-like phosphoesterase
EPEFKAOO_00013 1.39e-150 - - - - - - - -
EPEFKAOO_00014 1.56e-170 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
EPEFKAOO_00015 8.7e-166 yvoA_2 - - K ko:K03710 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
EPEFKAOO_00016 0.0 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EPEFKAOO_00017 4.68e-196 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
EPEFKAOO_00018 0.0 tex - - K ko:K06959 - ko00000 Tex-like protein N-terminal domain protein
EPEFKAOO_00019 9.91e-109 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
EPEFKAOO_00021 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
EPEFKAOO_00022 7.85e-242 lacM 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase
EPEFKAOO_00023 8.77e-213 - - - S ko:K07088 - ko00000 Sodium Bile acid symporter family
EPEFKAOO_00024 7.78e-165 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EPEFKAOO_00025 2.18e-213 - - - I - - - alpha/beta hydrolase fold
EPEFKAOO_00026 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
EPEFKAOO_00027 2e-143 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
EPEFKAOO_00028 3.53e-158 - 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EPEFKAOO_00029 6.52e-73 HA62_12640 - - S ko:K06975 - ko00000 GCN5-related N-acetyl-transferase
EPEFKAOO_00030 5.89e-126 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
EPEFKAOO_00031 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EPEFKAOO_00032 6.72e-265 yacL - - S - - - domain protein
EPEFKAOO_00033 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EPEFKAOO_00034 9.63e-130 ywlG - - S - - - Belongs to the UPF0340 family
EPEFKAOO_00035 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
EPEFKAOO_00036 1.25e-93 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EPEFKAOO_00037 2.04e-173 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EPEFKAOO_00038 5.57e-135 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
EPEFKAOO_00039 7.09e-30 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
EPEFKAOO_00040 2.48e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
EPEFKAOO_00041 8.34e-127 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
EPEFKAOO_00042 3.34e-68 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EPEFKAOO_00043 1.68e-157 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
EPEFKAOO_00044 3.15e-312 steT - - E ko:K03294 - ko00000 amino acid
EPEFKAOO_00045 3.88e-107 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EPEFKAOO_00046 8.24e-71 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
EPEFKAOO_00047 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
EPEFKAOO_00048 4.17e-237 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase subunit II
EPEFKAOO_00049 0.0 cydC - - CO ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
EPEFKAOO_00050 0.0 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EPEFKAOO_00051 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
EPEFKAOO_00052 0.0 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
EPEFKAOO_00053 8.93e-250 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EPEFKAOO_00054 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EPEFKAOO_00055 6.56e-48 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
EPEFKAOO_00056 3.69e-113 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
EPEFKAOO_00058 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EPEFKAOO_00059 3.97e-60 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EPEFKAOO_00060 6.48e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EPEFKAOO_00061 2.06e-28 - - - S - - - Protein of unknown function (DUF2508)
EPEFKAOO_00062 9.81e-149 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EPEFKAOO_00063 2.25e-70 yaaQ - - S - - - Cyclic-di-AMP receptor
EPEFKAOO_00064 5.56e-246 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
EPEFKAOO_00065 2.47e-74 yabA - - L - - - Involved in initiation control of chromosome replication
EPEFKAOO_00066 2.83e-202 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EPEFKAOO_00067 4.02e-189 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
EPEFKAOO_00068 0.0 ppx3 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
EPEFKAOO_00069 0.0 ppk 2.7.4.1 - P ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EPEFKAOO_00070 1.12e-219 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
EPEFKAOO_00071 8.55e-247 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
EPEFKAOO_00072 6.98e-206 - - - KT ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 YcbB domain
EPEFKAOO_00073 2.08e-239 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EPEFKAOO_00074 4.08e-218 arcC 2.7.2.2 - E ko:K00926 ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200 ko00000,ko00001,ko01000 Belongs to the carbamate kinase family
EPEFKAOO_00075 3.45e-305 arcA 3.5.3.6 - E ko:K01478 ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130 ko00000,ko00001,ko01000 Arginine
EPEFKAOO_00076 0.0 arcD - - E ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
EPEFKAOO_00077 8.37e-282 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
EPEFKAOO_00078 1.32e-273 arcT - - E - - - Aminotransferase
EPEFKAOO_00079 9.7e-168 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
EPEFKAOO_00080 1.93e-143 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 Ribosomal-protein-alanine acetyltransferase
EPEFKAOO_00081 3.65e-250 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EPEFKAOO_00083 3.83e-100 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
EPEFKAOO_00084 1.32e-97 - - - K - - - Transcriptional regulator, MarR family
EPEFKAOO_00085 8.86e-218 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EPEFKAOO_00086 4.18e-46 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
EPEFKAOO_00087 2.76e-219 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
EPEFKAOO_00088 2.67e-165 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
EPEFKAOO_00089 4.43e-290 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
EPEFKAOO_00090 3.46e-94 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
EPEFKAOO_00091 1.13e-97 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
EPEFKAOO_00092 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
EPEFKAOO_00093 3.74e-205 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EPEFKAOO_00094 2.69e-181 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 alpha subunit
EPEFKAOO_00095 1.55e-174 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
EPEFKAOO_00096 1.67e-117 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
EPEFKAOO_00097 1.04e-224 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
EPEFKAOO_00098 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
EPEFKAOO_00099 8.05e-149 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EPEFKAOO_00100 9.49e-57 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EPEFKAOO_00101 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
EPEFKAOO_00102 0.0 ydaO - - E - - - amino acid
EPEFKAOO_00103 4.12e-50 - - - - - - - -
EPEFKAOO_00104 6.92e-148 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
EPEFKAOO_00105 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
EPEFKAOO_00106 1.07e-166 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
EPEFKAOO_00107 4.64e-124 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EPEFKAOO_00108 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
EPEFKAOO_00109 1.24e-258 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EPEFKAOO_00110 1.97e-70 - - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain protein
EPEFKAOO_00111 4.15e-69 yvlD - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
EPEFKAOO_00112 4.82e-227 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EPEFKAOO_00113 1.94e-211 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EPEFKAOO_00114 9.09e-236 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
EPEFKAOO_00115 7.64e-220 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
EPEFKAOO_00116 1.06e-188 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Carbon-nitrogen hydrolase
EPEFKAOO_00117 1.08e-289 mtnE - - E ko:K08969 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
EPEFKAOO_00118 6.21e-241 ykpB 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EPEFKAOO_00119 4.01e-104 yphH - - S - - - Cupin domain
EPEFKAOO_00120 8.22e-167 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
EPEFKAOO_00121 3.44e-200 metA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
EPEFKAOO_00122 4.22e-215 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
EPEFKAOO_00123 3.96e-253 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
EPEFKAOO_00124 1.12e-217 hdhL 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
EPEFKAOO_00125 1.07e-178 - - - S - - - haloacid dehalogenase-like hydrolase
EPEFKAOO_00126 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
EPEFKAOO_00127 5.06e-145 yfbR - - S ko:K07023 - ko00000 HD containing hydrolase-like enzyme
EPEFKAOO_00129 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
EPEFKAOO_00130 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
EPEFKAOO_00131 1.25e-261 - - - - - - - -
EPEFKAOO_00132 1.35e-206 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
EPEFKAOO_00133 2e-240 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
EPEFKAOO_00134 6.71e-214 whiA - - K ko:K09762 - ko00000 May be required for sporulation
EPEFKAOO_00135 2.96e-132 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
EPEFKAOO_00139 3.82e-23 - - - - - - - -
EPEFKAOO_00140 1.31e-244 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
EPEFKAOO_00141 4.22e-287 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
EPEFKAOO_00142 2.92e-184 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
EPEFKAOO_00143 0.0 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
EPEFKAOO_00144 0.0 yifK - - E ko:K03293 - ko00000 Amino acid permease
EPEFKAOO_00145 0.0 eriC - - P ko:K03281 - ko00000 chloride
EPEFKAOO_00146 6.82e-46 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
EPEFKAOO_00147 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
EPEFKAOO_00148 4.66e-110 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
EPEFKAOO_00149 2.87e-140 - - - - - - - -
EPEFKAOO_00150 4.52e-175 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EPEFKAOO_00151 9.74e-229 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
EPEFKAOO_00152 4.21e-105 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
EPEFKAOO_00153 2.24e-117 - - - K - - - Acetyltransferase (GNAT) domain
EPEFKAOO_00154 4e-133 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
EPEFKAOO_00155 2.34e-212 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
EPEFKAOO_00156 1.61e-192 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EPEFKAOO_00157 3.41e-151 ybbR - - S - - - YbbR-like protein
EPEFKAOO_00158 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EPEFKAOO_00159 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
EPEFKAOO_00160 2.55e-68 - - - - - - - -
EPEFKAOO_00161 1.36e-261 oatA - - I - - - Acyltransferase
EPEFKAOO_00162 2.13e-193 XK27_02985 - - S - - - Sucrose-6F-phosphate phosphohydrolase
EPEFKAOO_00163 2.32e-106 lytE - - M - - - Lysin motif
EPEFKAOO_00164 6.96e-222 - - - S - - - Conserved hypothetical protein 698
EPEFKAOO_00165 4.95e-215 - - - K - - - LysR substrate binding domain
EPEFKAOO_00167 1.1e-07 - 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Arginase family
EPEFKAOO_00168 1.54e-221 - 1.3.1.9 - S ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Nitronate monooxygenase
EPEFKAOO_00169 6.7e-72 - - - K - - - Helix-turn-helix domain
EPEFKAOO_00170 2.37e-135 - - - S - - - Domain of unknown function (DUF4767)
EPEFKAOO_00171 3.24e-109 - - - - - - - -
EPEFKAOO_00172 0.0 pacL - - P - - - Cation transporter/ATPase, N-terminus
EPEFKAOO_00173 0.0 - 1.7.2.5 - P ko:K04561 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Cytochrome C and Quinol oxidase polypeptide I
EPEFKAOO_00174 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
EPEFKAOO_00175 1.36e-145 - - - T - - - Region found in RelA / SpoT proteins
EPEFKAOO_00176 6.69e-101 dltr - - K - - - response regulator
EPEFKAOO_00177 5.13e-165 sptS - - T - - - Histidine kinase
EPEFKAOO_00178 2.29e-223 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
EPEFKAOO_00179 2.05e-137 - - - K - - - acetyltransferase
EPEFKAOO_00180 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
EPEFKAOO_00181 2.73e-204 - - - EG - - - EamA-like transporter family
EPEFKAOO_00182 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
EPEFKAOO_00183 1.45e-152 - - - S ko:K03975 - ko00000 SNARE associated Golgi protein
EPEFKAOO_00184 1.92e-155 pgm3 - - G - - - phosphoglycerate mutase
EPEFKAOO_00185 1.69e-296 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EPEFKAOO_00186 6.22e-266 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
EPEFKAOO_00187 2.05e-172 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
EPEFKAOO_00188 0.0 - - - E - - - amino acid
EPEFKAOO_00189 4.58e-114 - - - K - - - FR47-like protein
EPEFKAOO_00190 4.75e-313 yhgE - - V ko:K01421 - ko00000 domain protein
EPEFKAOO_00191 6e-122 - - - K - - - Transcriptional regulator (TetR family)
EPEFKAOO_00192 2.38e-252 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
EPEFKAOO_00193 8.3e-205 - - - - - - - -
EPEFKAOO_00194 3.58e-10 - 3.2.1.14 GH18 - ko:K01183 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 -
EPEFKAOO_00195 7.28e-110 zur - - P ko:K02076,ko:K03711 - ko00000,ko03000 Belongs to the Fur family
EPEFKAOO_00196 9.61e-137 gmk2 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Guanylate kinase
EPEFKAOO_00197 3.13e-95 - - - F - - - Nudix hydrolase
EPEFKAOO_00198 6.65e-260 yhdG - - E ko:K03294 - ko00000 Amino Acid
EPEFKAOO_00199 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
EPEFKAOO_00200 2.73e-227 - 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
EPEFKAOO_00201 5.93e-149 - - - S - - - HAD hydrolase, family IA, variant
EPEFKAOO_00202 0.0 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
EPEFKAOO_00203 8.41e-235 - 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Ribonucleotide reductase, small chain
EPEFKAOO_00204 1.08e-216 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Ribonucleotide reductase, small chain
EPEFKAOO_00205 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EPEFKAOO_00206 1.64e-108 nrdI - - F ko:K03647 - ko00000 NrdI Flavodoxin like
EPEFKAOO_00207 8.3e-141 yciB - - M - - - ErfK YbiS YcfS YnhG
EPEFKAOO_00209 1.64e-262 yngD - - S ko:K07097 - ko00000 DHHA1 domain
EPEFKAOO_00210 0.0 - - - S - - - ABC transporter, ATP-binding protein
EPEFKAOO_00211 5.66e-231 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
EPEFKAOO_00212 3.76e-193 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
EPEFKAOO_00213 2.28e-171 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EPEFKAOO_00215 4.39e-286 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
EPEFKAOO_00216 2.61e-298 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
EPEFKAOO_00217 7.93e-217 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
EPEFKAOO_00218 1.84e-60 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NLP P60 protein
EPEFKAOO_00219 1.28e-78 - - - S - - - enterobacterial common antigen metabolic process
EPEFKAOO_00220 9.46e-87 - - GT4 M ko:K02840 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 Glycosyl transferases group 1
EPEFKAOO_00221 3.75e-275 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
EPEFKAOO_00222 2.58e-276 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
EPEFKAOO_00223 1.11e-94 - - - M - - - Core-2/I-Branching enzyme
EPEFKAOO_00224 6.13e-107 - - - M - - - transferase activity, transferring glycosyl groups
EPEFKAOO_00225 6.46e-84 - - - - - - - -
EPEFKAOO_00226 7.17e-84 - - - M - - - Domain of unknown function (DUF4422)
EPEFKAOO_00227 7.97e-41 - - - M - - - biosynthesis protein
EPEFKAOO_00228 1.71e-191 cps1D - - M - - - Domain of unknown function (DUF4422)
EPEFKAOO_00229 2.45e-152 rfbP - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 Bacterial sugar transferase
EPEFKAOO_00230 2.05e-188 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
EPEFKAOO_00232 4.37e-43 - - - S - - - Protein of unknown function (DUF2922)
EPEFKAOO_00233 1.01e-192 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
EPEFKAOO_00234 0.0 XK27_08315 - - M - - - Sulfatase
EPEFKAOO_00235 1.17e-214 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
EPEFKAOO_00236 3.34e-101 ykuP - - C ko:K03839 - ko00000 Flavodoxin
EPEFKAOO_00237 2.78e-98 gtcA - - S - - - Teichoic acid glycosylation protein
EPEFKAOO_00240 1.42e-305 yfmL - - L - - - DEAD DEAH box helicase
EPEFKAOO_00241 4.94e-244 mocA - - S - - - Oxidoreductase
EPEFKAOO_00242 2.11e-82 - - - S - - - Domain of unknown function (DUF4828)
EPEFKAOO_00243 1.73e-132 - 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
EPEFKAOO_00244 1.29e-205 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
EPEFKAOO_00245 0.0 gshA 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
EPEFKAOO_00246 2.89e-177 - - - S - - - NADPH-dependent FMN reductase
EPEFKAOO_00247 1.17e-43 yneR - - S - - - Belongs to the HesB IscA family
EPEFKAOO_00248 0.0 ykpA - - S - - - ABC transporter, ATP-binding protein
EPEFKAOO_00249 1.76e-113 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
EPEFKAOO_00250 8.96e-136 - - - - - - - -
EPEFKAOO_00251 6.55e-275 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
EPEFKAOO_00252 5.65e-130 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
EPEFKAOO_00253 1.56e-161 - - - EGP - - - Major Facilitator Superfamily
EPEFKAOO_00254 1.52e-129 ogt 2.1.1.63 - L ko:K00567 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EPEFKAOO_00255 2.73e-133 - - - S - - - CAAX protease self-immunity
EPEFKAOO_00257 1.67e-152 - - - Q - - - Methyltransferase domain
EPEFKAOO_00258 1.03e-120 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
EPEFKAOO_00259 1.28e-67 - - - K - - - 2 iron, 2 sulfur cluster binding
EPEFKAOO_00260 0.0 sufI - - Q - - - Multicopper oxidase
EPEFKAOO_00261 5.51e-116 - - - S ko:K19055 - ko00000,ko01000,ko03016 Aminoacyl-tRNA editing domain
EPEFKAOO_00262 1.47e-32 ddaH 3.5.3.18 - E ko:K01482 - ko00000,ko01000,ko04147 dimethylargininase activity
EPEFKAOO_00263 1.81e-96 - 3.5.3.18 - E ko:K01482 - ko00000,ko01000,ko04147 Amidinotransferase
EPEFKAOO_00265 1.69e-168 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
EPEFKAOO_00266 5.37e-81 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
EPEFKAOO_00267 1.31e-181 - - - S ko:K22230 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase family, NAD-binding Rossmann fold
EPEFKAOO_00270 5.23e-235 - - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
EPEFKAOO_00271 4.45e-116 - - - L ko:K07497 - ko00000 hmm pf00665
EPEFKAOO_00272 1.04e-100 cas2 - - L ko:K09951 - ko00000,ko02048 CRISPR-associated protein (Cas_Cas2CT1978)
EPEFKAOO_00273 8.83e-160 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EPEFKAOO_00274 1.8e-21 casE - - S ko:K19126 - ko00000,ko02048 CRISPR_assoc
EPEFKAOO_00275 1.41e-286 aadAT - - EK ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko01000 Aminotransferase, class I
EPEFKAOO_00276 3.86e-197 gshAB 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
EPEFKAOO_00277 8.93e-185 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
EPEFKAOO_00279 3.97e-279 - - - I - - - transferase activity, transferring acyl groups other than amino-acyl groups
EPEFKAOO_00281 6.53e-123 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
EPEFKAOO_00282 5.05e-128 - - - K - - - Virulence activator alpha C-term
EPEFKAOO_00283 9.67e-104 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Belongs to the NDK family
EPEFKAOO_00284 4.81e-08 - - - S - - - SNARE associated Golgi protein
EPEFKAOO_00285 4.53e-303 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
EPEFKAOO_00286 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EPEFKAOO_00288 0.0 yifK - - E ko:K03293 - ko00000 Amino acid permease
EPEFKAOO_00290 0.0 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
EPEFKAOO_00291 3.89e-209 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
EPEFKAOO_00292 5.76e-211 - 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 3-hydroxyacyl-CoA dehydrogenase
EPEFKAOO_00293 0.0 - - - I - - - Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EPEFKAOO_00294 5.3e-207 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
EPEFKAOO_00296 2.27e-290 - - - - - - - -
EPEFKAOO_00297 6.79e-249 flp - - V - - - Beta-lactamase
EPEFKAOO_00298 8.23e-117 pgpA - - I - - - Phosphatidylglycerophosphatase A
EPEFKAOO_00299 5.11e-160 - - - S ko:K07090 - ko00000 membrane transporter protein
EPEFKAOO_00300 4.46e-237 XK27_12525 - - S - - - AI-2E family transporter
EPEFKAOO_00301 5.4e-273 atoB 1.1.1.88, 2.3.1.9 - I ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
EPEFKAOO_00302 3.46e-207 rssA - - S - - - Phospholipase, patatin family
EPEFKAOO_00303 9.93e-217 - - - K - - - LysR substrate binding domain
EPEFKAOO_00304 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
EPEFKAOO_00305 4.39e-109 - - - S - - - Domain of unknown function (DUF4352)
EPEFKAOO_00306 3.5e-145 yicL - - EG - - - EamA-like transporter family
EPEFKAOO_00307 1.59e-85 - - - - - - - -
EPEFKAOO_00310 1.45e-44 - - - - - - - -
EPEFKAOO_00311 3.96e-89 - - - S - - - pyridoxamine 5-phosphate
EPEFKAOO_00312 5.37e-230 - - - K - - - WYL domain
EPEFKAOO_00313 4.66e-312 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
EPEFKAOO_00314 1.65e-53 XK27_08630 - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
EPEFKAOO_00315 1.17e-214 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
EPEFKAOO_00316 2.27e-269 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
EPEFKAOO_00317 8.84e-143 adh 1.1.1.1 - C ko:K00001,ko:K18369 ko00010,ko00071,ko00350,ko00625,ko00626,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Zinc-binding dehydrogenase
EPEFKAOO_00318 4.39e-16 adh 1.1.1.1 - C ko:K00001,ko:K18369 ko00010,ko00071,ko00350,ko00625,ko00626,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Zinc-binding dehydrogenase
EPEFKAOO_00319 3.54e-277 - - - G - - - Transporter, major facilitator family protein
EPEFKAOO_00320 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
EPEFKAOO_00321 1.2e-201 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EPEFKAOO_00322 1.34e-74 yuxO - - Q - - - Thioesterase superfamily
EPEFKAOO_00323 6.51e-45 - - - L - - - PFAM Transposase, IS204 IS1001 IS1096 IS1165
EPEFKAOO_00324 1.63e-76 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
EPEFKAOO_00325 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EPEFKAOO_00326 1.89e-205 hdhL 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
EPEFKAOO_00328 1.38e-06 adhC 1.1.1.90 - C ko:K00055 ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Zn-dependent alcohol dehydrogenases, class III
EPEFKAOO_00329 1.08e-29 - - - S - - - Enoyl-(Acyl carrier protein) reductase
EPEFKAOO_00330 7.06e-221 - - - K - - - Bacterial regulatory helix-turn-helix protein, lysR family
EPEFKAOO_00331 4.36e-155 - 4.2.1.1 - P ko:K01674 ko00910,map00910 ko00000,ko00001,ko01000 Eukaryotic-type carbonic anhydrase
EPEFKAOO_00332 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
EPEFKAOO_00333 2.95e-264 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarA family
EPEFKAOO_00334 1.81e-223 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
EPEFKAOO_00335 2.11e-98 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EPEFKAOO_00336 8.6e-93 esbA - - S - - - Family of unknown function (DUF5322)
EPEFKAOO_00337 3.77e-93 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease HI
EPEFKAOO_00338 1.36e-139 XK27_02070 - - S ko:K07078 - ko00000 Nitroreductase family
EPEFKAOO_00339 1.02e-200 yckB - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
EPEFKAOO_00340 1.05e-277 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
EPEFKAOO_00341 9.95e-108 - - - F - - - Hydrolase, NUDIX family
EPEFKAOO_00342 4.37e-271 - - - S ko:K06915 - ko00000 AAA-like domain
EPEFKAOO_00343 0.0 fusA1 - - J - - - elongation factor G
EPEFKAOO_00344 2.08e-75 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
EPEFKAOO_00345 7.6e-145 ypsA - - S - - - Belongs to the UPF0398 family
EPEFKAOO_00346 2.08e-153 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
EPEFKAOO_00347 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
EPEFKAOO_00348 6.64e-205 - - - EG - - - EamA-like transporter family
EPEFKAOO_00349 3.33e-243 tas3 - - C ko:K19265 - ko00000,ko01000 Aldo keto reductase family protein
EPEFKAOO_00350 3.82e-190 ypuA - - S - - - Protein of unknown function (DUF1002)
EPEFKAOO_00351 4.14e-173 dnaD - - L ko:K02086 - ko00000 DnaD domain protein
EPEFKAOO_00352 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
EPEFKAOO_00353 2.71e-114 ypmB - - S - - - Protein conserved in bacteria
EPEFKAOO_00354 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
EPEFKAOO_00355 3.08e-214 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 mevalonate kinase
EPEFKAOO_00356 3.68e-231 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
EPEFKAOO_00357 1e-271 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
EPEFKAOO_00358 5.29e-263 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
EPEFKAOO_00359 1.6e-119 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
EPEFKAOO_00360 2.64e-130 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
EPEFKAOO_00361 9.79e-122 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
EPEFKAOO_00362 2.23e-116 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
EPEFKAOO_00363 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
EPEFKAOO_00364 1.77e-196 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
EPEFKAOO_00365 3.21e-213 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
EPEFKAOO_00366 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
EPEFKAOO_00367 5.1e-265 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
EPEFKAOO_00368 1.62e-312 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
EPEFKAOO_00369 5.67e-231 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
EPEFKAOO_00370 1.34e-230 - 1.1.1.26 - CH ko:K00015 ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EPEFKAOO_00371 3.82e-33 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class-V
EPEFKAOO_00372 4.31e-33 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class-V
EPEFKAOO_00373 2.71e-88 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class-V
EPEFKAOO_00374 1.04e-53 - - - C - - - Protein of unknown function (DUF1116)
EPEFKAOO_00376 0.000699 - - - S - - - Protein of unknown function (DUF2877)
EPEFKAOO_00377 6.16e-157 cpkA 2.7.2.2 - E ko:K00926 ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200 ko00000,ko00001,ko01000 Amino acid kinase family
EPEFKAOO_00378 7.41e-227 rihA - - F ko:K01250 - ko00000,ko01000 Inosine-uridine preferring nucleoside hydrolase
EPEFKAOO_00379 3.88e-160 - - - C - - - nitroreductase
EPEFKAOO_00380 1.98e-176 - - - E - - - GDSL-like Lipase/Acylhydrolase family
EPEFKAOO_00381 6.16e-70 - - - S - - - Mazg nucleotide pyrophosphohydrolase
EPEFKAOO_00382 3.65e-251 adh1 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
EPEFKAOO_00383 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
EPEFKAOO_00384 6.83e-115 - - - K - - - Transcriptional regulator
EPEFKAOO_00386 3.03e-181 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
EPEFKAOO_00388 5.47e-198 metQ1 - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
EPEFKAOO_00389 6.37e-259 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
EPEFKAOO_00390 0.0 - - - L - - - DNA helicase
EPEFKAOO_00391 7.95e-222 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
EPEFKAOO_00392 2.94e-283 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
EPEFKAOO_00393 9.16e-240 - - - - - - - -
EPEFKAOO_00394 2.7e-164 cobB - - K ko:K12410 - ko00000,ko01000 SIR2 family
EPEFKAOO_00395 2.38e-272 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 transporter
EPEFKAOO_00396 9.96e-209 yunF - - F - - - Protein of unknown function DUF72
EPEFKAOO_00397 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EPEFKAOO_00398 5.46e-188 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
EPEFKAOO_00399 3.77e-127 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EPEFKAOO_00400 6.18e-206 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
EPEFKAOO_00401 4.04e-205 ispE 2.7.1.148 - F ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EPEFKAOO_00402 4.04e-212 psaA - - P ko:K02077,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
EPEFKAOO_00403 1.98e-123 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
EPEFKAOO_00404 2.81e-166 - - - U ko:K02075 - ko00000,ko00002,ko02000 ABC 3 transport family
EPEFKAOO_00405 2.13e-193 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
EPEFKAOO_00406 9.91e-302 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EPEFKAOO_00407 1.81e-226 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EPEFKAOO_00408 3.55e-76 - - - - - - - -
EPEFKAOO_00409 8.27e-184 yidA - - S - - - hydrolase
EPEFKAOO_00410 0.0 ywfO - - S ko:K06885 - ko00000 HD domain protein
EPEFKAOO_00411 5.23e-97 ywiB - - S - - - Domain of unknown function (DUF1934)
EPEFKAOO_00412 2.16e-97 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
EPEFKAOO_00413 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
EPEFKAOO_00414 7.23e-301 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EPEFKAOO_00415 3.85e-55 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
EPEFKAOO_00416 1.81e-64 pmrA - - EGP ko:K08161 - ko00000,ko02000 MFS_1 like family
EPEFKAOO_00417 1.36e-97 pmrA - - EGP ko:K08161 - ko00000,ko02000 MFS_1 like family
EPEFKAOO_00418 1.1e-313 - - - U - - - Belongs to the major facilitator superfamily
EPEFKAOO_00419 3.42e-232 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
EPEFKAOO_00420 3.22e-214 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EPEFKAOO_00421 1.49e-77 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EPEFKAOO_00422 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EPEFKAOO_00423 5.5e-67 ylxQ - - J - - - ribosomal protein
EPEFKAOO_00424 3.71e-64 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
EPEFKAOO_00425 1.11e-281 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
EPEFKAOO_00426 8.99e-109 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
EPEFKAOO_00427 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
EPEFKAOO_00428 1.46e-262 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
EPEFKAOO_00429 1.22e-251 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EPEFKAOO_00430 3.5e-264 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EPEFKAOO_00431 5.88e-176 argB 2.7.2.8 - F ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
EPEFKAOO_00432 2.2e-273 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine
EPEFKAOO_00433 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EPEFKAOO_00434 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
EPEFKAOO_00435 3.56e-297 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
EPEFKAOO_00436 8.21e-174 cdsA 2.7.7.41 - I ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
EPEFKAOO_00437 2.7e-185 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EPEFKAOO_00438 6.51e-122 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
EPEFKAOO_00439 6.84e-167 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
EPEFKAOO_00440 3.4e-197 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EPEFKAOO_00441 3.14e-181 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
EPEFKAOO_00442 2.67e-62 yazA - - L ko:K07461 - ko00000 GIY-YIG catalytic domain protein
EPEFKAOO_00443 6.86e-176 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
EPEFKAOO_00444 3.06e-150 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
EPEFKAOO_00445 1.05e-36 XK26_06720 - - S ko:K09976 - ko00000 Uncharacterised protein family (UPF0154)
EPEFKAOO_00446 1.97e-49 ynzC - - S - - - UPF0291 protein
EPEFKAOO_00447 4.36e-149 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EPEFKAOO_00448 7.4e-275 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
EPEFKAOO_00449 2.76e-155 lutA - - C ko:K18928 - ko00000 Cysteine-rich domain
EPEFKAOO_00450 8.75e-307 lutB - - C ko:K18929 - ko00000 4Fe-4S dicluster domain
EPEFKAOO_00451 6.8e-111 lutC - - S ko:K00782 - ko00000 LUD domain
EPEFKAOO_00452 7.2e-38 - - - M - - - LPXTG-motif cell wall anchor domain protein
EPEFKAOO_00453 1.31e-61 - - - M - - - LPXTG-motif cell wall anchor domain protein
EPEFKAOO_00454 1.99e-11 - - - Q - - - Signal peptide protein, YSIRK family
EPEFKAOO_00455 3.02e-35 yitW - - S - - - DNA methyltransferase
EPEFKAOO_00456 3.09e-141 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
EPEFKAOO_00457 1.15e-82 sdhB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
EPEFKAOO_00460 6.59e-76 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
EPEFKAOO_00461 0.0 - - - E ko:K03294 - ko00000 Amino Acid
EPEFKAOO_00462 2.22e-182 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
EPEFKAOO_00463 1.52e-114 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EPEFKAOO_00464 9.17e-54 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
EPEFKAOO_00465 4.94e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
EPEFKAOO_00466 2.78e-158 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
EPEFKAOO_00467 1.56e-177 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
EPEFKAOO_00468 1.74e-195 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
EPEFKAOO_00469 1.18e-196 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
EPEFKAOO_00470 3.3e-204 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
EPEFKAOO_00471 4.15e-169 - - - K ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C-terminal domain protein
EPEFKAOO_00472 3.43e-145 - - - - - - - -
EPEFKAOO_00474 0.0 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EPEFKAOO_00475 1.72e-75 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
EPEFKAOO_00476 1.54e-279 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
EPEFKAOO_00477 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
EPEFKAOO_00478 1.62e-165 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
EPEFKAOO_00479 1.65e-47 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
EPEFKAOO_00480 2.2e-215 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
EPEFKAOO_00481 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EPEFKAOO_00482 0.0 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
EPEFKAOO_00483 7.09e-76 yloU - - S - - - Asp23 family, cell envelope-related function
EPEFKAOO_00484 1e-35 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
EPEFKAOO_00485 4.7e-163 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
EPEFKAOO_00486 1.1e-151 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
EPEFKAOO_00487 1.78e-210 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
EPEFKAOO_00488 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
EPEFKAOO_00489 1.68e-169 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
EPEFKAOO_00490 5.57e-316 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EPEFKAOO_00491 5.61e-224 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EPEFKAOO_00492 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EPEFKAOO_00493 2.42e-281 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EPEFKAOO_00494 1.9e-61 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
EPEFKAOO_00495 1.03e-146 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
EPEFKAOO_00497 3.45e-74 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
EPEFKAOO_00498 1.67e-181 yceF - - P ko:K05794 - ko00000 membrane
EPEFKAOO_00499 2.02e-215 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
EPEFKAOO_00500 6.8e-220 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
EPEFKAOO_00501 1.93e-302 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
EPEFKAOO_00502 1.61e-191 qorB 1.6.5.2 - GM ko:K19267 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NmrA-like family
EPEFKAOO_00503 3.31e-162 pgm3 - - G - - - phosphoglycerate mutase family
EPEFKAOO_00504 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
EPEFKAOO_00505 1.3e-110 - - - - - - - -
EPEFKAOO_00506 1.69e-145 flp - - K ko:K21562 - ko00000,ko03000 helix_turn_helix, cAMP Regulatory protein
EPEFKAOO_00507 8.02e-130 dpsB - - P - - - Belongs to the Dps family
EPEFKAOO_00508 3.19e-45 copZ - - P - - - Heavy-metal-associated domain
EPEFKAOO_00509 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 P-type ATPase
EPEFKAOO_00510 1.51e-235 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
EPEFKAOO_00511 1.39e-230 iunH1 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 nucleoside hydrolase
EPEFKAOO_00512 1.66e-130 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
EPEFKAOO_00513 0.0 - - - S ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
EPEFKAOO_00514 1.06e-149 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
EPEFKAOO_00515 1.78e-22 - - - - - - - -
EPEFKAOO_00516 0.0 nhaK - - P ko:K03316 - ko00000 Sodium proton antiporter
EPEFKAOO_00517 1.12e-245 lplL 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Bacterial lipoate protein ligase C-terminus
EPEFKAOO_00518 9.46e-96 - - - O - - - OsmC-like protein
EPEFKAOO_00519 6.19e-239 ybcH - - D ko:K06889 - ko00000 Alpha beta
EPEFKAOO_00520 2.22e-98 - - - K - - - Transcriptional regulator
EPEFKAOO_00521 7.82e-203 - - - - - - - -
EPEFKAOO_00522 1.25e-09 - - - - - - - -
EPEFKAOO_00523 6.25e-78 - - - - - - - -
EPEFKAOO_00524 2.52e-97 uspA3 - - T - - - universal stress protein
EPEFKAOO_00526 2.71e-132 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 prohibitin homologues
EPEFKAOO_00527 6.11e-311 glpT - - G ko:K02445 - ko00000,ko02000 Major Facilitator Superfamily
EPEFKAOO_00528 0.0 tkt 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EPEFKAOO_00529 3.97e-174 tal 2.2.1.2 - H ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase/Fructose-6-phosphate aldolase
EPEFKAOO_00530 5.46e-161 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EPEFKAOO_00531 3.97e-48 tkt 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EPEFKAOO_00532 1.16e-85 tkt 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EPEFKAOO_00533 2.25e-144 B4168_4126 - - L ko:K07493 - ko00000 Transposase
EPEFKAOO_00534 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
EPEFKAOO_00535 5.9e-189 - - - S - - - haloacid dehalogenase-like hydrolase
EPEFKAOO_00536 3.81e-169 gntR - - K - - - UbiC transcription regulator-associated domain protein
EPEFKAOO_00537 4.23e-115 ebsC - - J ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EPEFKAOO_00538 3.78e-167 - - - - - - - -
EPEFKAOO_00539 0.0 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
EPEFKAOO_00540 3.73e-199 - - - G - - - Xylose isomerase domain protein TIM barrel
EPEFKAOO_00541 4.18e-113 - - - K - - - Domain of unknown function (DUF1836)
EPEFKAOO_00542 1.19e-116 - - - GM - - - epimerase
EPEFKAOO_00543 0.0 yhdP - - S - - - Transporter associated domain
EPEFKAOO_00544 3.05e-109 nrdI - - F ko:K03647 - ko00000 Belongs to the NrdI family
EPEFKAOO_00545 8.99e-99 - - - S ko:K04750 - ko00000 3-demethylubiquinone-9 3-methyltransferase
EPEFKAOO_00546 4.9e-264 yycB - - P ko:K03449 - ko00000,ko02000 Transporter, major facilitator family protein
EPEFKAOO_00547 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EPEFKAOO_00548 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EPEFKAOO_00549 2.13e-106 usp5 - - T - - - universal stress protein
EPEFKAOO_00550 5.3e-104 - - - K ko:K03719 - ko00000,ko03000,ko03036 AsnC family
EPEFKAOO_00551 5.66e-182 kduD 1.1.1.127 - IQ ko:K00065 ko00040,map00040 ko00000,ko00001,ko01000 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EPEFKAOO_00552 4.13e-230 - - - K ko:K02525 - ko00000,ko03000 helix_turn _helix lactose operon repressor
EPEFKAOO_00553 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
EPEFKAOO_00554 1.29e-298 gltT - - U ko:K03309,ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
EPEFKAOO_00555 6.15e-161 - - - S - - - Membrane
EPEFKAOO_00556 1.11e-50 - - - L ko:K07483 - ko00000 Transposase
EPEFKAOO_00557 8.93e-141 - - - L - - - 4.5 Transposon and IS
EPEFKAOO_00558 0.0 dld 1.1.5.12 - C ko:K03777 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 D-lactate dehydrogenase, membrane binding
EPEFKAOO_00559 5.92e-157 ribB 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EPEFKAOO_00561 1.01e-83 - - - S - - - YjbR
EPEFKAOO_00562 4.9e-153 - - - S ko:K07126 - ko00000 Sel1-like repeats.
EPEFKAOO_00563 2.41e-52 - - - K - - - Psort location CytoplasmicMembrane, score
EPEFKAOO_00564 1.12e-204 - - - K - - - helix_turn_helix, arabinose operon control protein
EPEFKAOO_00565 1.9e-107 - - - S - - - Membrane
EPEFKAOO_00566 0.0 galA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
EPEFKAOO_00567 2.13e-57 glpQ1 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
EPEFKAOO_00568 2.08e-15 glpQ1 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
EPEFKAOO_00569 1.02e-58 yrfB - - C - - - NADH:flavin oxidoreductase / NADH oxidase family
EPEFKAOO_00570 4.92e-115 rmeB - - K - - - transcriptional regulator, MerR family
EPEFKAOO_00571 5.14e-169 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
EPEFKAOO_00572 9.77e-144 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EPEFKAOO_00573 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
EPEFKAOO_00574 6.17e-35 - - - S - - - Protein of unknown function (DUF4256)
EPEFKAOO_00575 6.01e-60 - - - G - - - Protein of unknown function (DUF4038)
EPEFKAOO_00576 2.87e-36 - - - G - - - Protein of unknown function (DUF4038)
EPEFKAOO_00577 2.61e-234 - - - C - - - Oxidoreductase
EPEFKAOO_00578 1.03e-112 deoR - - K ko:K05346 - ko00000,ko03000 sugar-binding domain protein
EPEFKAOO_00579 3.36e-145 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
EPEFKAOO_00580 2.83e-203 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 pyrimidine-nucleoside phosphorylase
EPEFKAOO_00581 3.81e-245 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
EPEFKAOO_00582 1.64e-115 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EPEFKAOO_00584 7.18e-58 cas2 - - L ko:K09951 - ko00000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EPEFKAOO_00585 1.45e-214 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EPEFKAOO_00586 5.16e-103 csm5 - - L ko:K19140 - ko00000,ko02048 RAMP superfamily
EPEFKAOO_00587 6.14e-96 - - - L ko:K19139 - ko00000,ko02048 CRISPR-associated RAMP protein, Csm4 family
EPEFKAOO_00588 8.36e-103 csm3 - - L ko:K09002 - ko00000,ko02048 RAMP superfamily
EPEFKAOO_00589 1.7e-26 - - - L ko:K19138 - ko00000,ko02048 Pfam:DUF310
EPEFKAOO_00590 6.84e-279 csm1 - - S ko:K07016 - ko00000,ko02048 CRISPR-associated protein Csm1 family
EPEFKAOO_00591 1.05e-08 cas6 - - S - - - CRISPR-associated endoribonuclease Cas6
EPEFKAOO_00592 1.72e-35 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
EPEFKAOO_00594 5.28e-132 - - - K - - - DNA-templated transcription, initiation
EPEFKAOO_00595 3.94e-89 - - - V - - - site-specific DNA-methyltransferase (adenine-specific) activity
EPEFKAOO_00596 8.12e-121 mrr2 - - L ko:K07448 - ko00000,ko02048 restriction endonuclease
EPEFKAOO_00597 0.0 - - - L - - - Type III restriction enzyme, res subunit
EPEFKAOO_00598 1.21e-120 - - - L - - - Type III restriction enzyme, res subunit
EPEFKAOO_00599 1.56e-36 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
EPEFKAOO_00600 1.96e-215 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
EPEFKAOO_00601 1.41e-212 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EPEFKAOO_00602 9.89e-207 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 Dehydrogenase
EPEFKAOO_00603 2.41e-235 fruR3 - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional regulator, LacI family
EPEFKAOO_00604 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
EPEFKAOO_00605 2.7e-176 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
EPEFKAOO_00606 1.39e-288 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
EPEFKAOO_00608 4.91e-240 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
EPEFKAOO_00610 3.66e-315 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EPEFKAOO_00611 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 Putative exonuclease SbcCD, C subunit
EPEFKAOO_00612 6.1e-277 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
EPEFKAOO_00613 1.63e-08 dltX - - S - - - D-Ala-teichoic acid biosynthesis protein
EPEFKAOO_00614 0.0 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EPEFKAOO_00615 3.06e-304 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
EPEFKAOO_00616 3.78e-48 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EPEFKAOO_00617 8.3e-311 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EPEFKAOO_00618 3.1e-154 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
EPEFKAOO_00619 3.79e-248 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
EPEFKAOO_00620 2.79e-312 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EPEFKAOO_00621 3.56e-281 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
EPEFKAOO_00622 2.13e-141 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
EPEFKAOO_00623 3.47e-244 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EPEFKAOO_00624 5.47e-197 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
EPEFKAOO_00625 0.0 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Poly(Glycerol-phosphate) alpha-glucosyltransferase
EPEFKAOO_00626 0.0 tagE6 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
EPEFKAOO_00627 1.97e-62 - - - - - - - -
EPEFKAOO_00628 6.19e-149 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EPEFKAOO_00629 2.38e-168 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
EPEFKAOO_00630 8.04e-124 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EPEFKAOO_00631 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
EPEFKAOO_00632 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EPEFKAOO_00633 2.81e-212 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
EPEFKAOO_00634 3.57e-119 - - - K - - - transcriptional regulator
EPEFKAOO_00635 5.38e-165 ybhF_2 - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
EPEFKAOO_00636 2.15e-242 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
EPEFKAOO_00637 3.67e-86 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
EPEFKAOO_00638 7.77e-77 glpQ4 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 phosphodiesterase
EPEFKAOO_00639 1.12e-254 glpQ4 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 phosphodiesterase
EPEFKAOO_00640 1.26e-210 - - - C - - - Aldo keto reductase
EPEFKAOO_00641 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
EPEFKAOO_00642 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
EPEFKAOO_00643 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EPEFKAOO_00644 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 associated with various cellular activities
EPEFKAOO_00645 5.71e-48 - - - - - - - -
EPEFKAOO_00646 4.85e-278 - - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
EPEFKAOO_00647 5.06e-234 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EPEFKAOO_00648 6.65e-234 - - - D ko:K06889 - ko00000 Alpha beta
EPEFKAOO_00649 1.04e-244 - 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
EPEFKAOO_00650 1.21e-141 ysdA - - CP ko:K01992 - ko00000,ko00002,ko02000 transmembrane transport
EPEFKAOO_00651 7.69e-150 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
EPEFKAOO_00652 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
EPEFKAOO_00653 0.0 malT - - G ko:K16211 - ko00000,ko02000 Major Facilitator
EPEFKAOO_00654 2.68e-224 malR1 - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
EPEFKAOO_00655 3.03e-94 ywnA - - K - - - Transcriptional regulator
EPEFKAOO_00656 1.01e-105 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EPEFKAOO_00657 1.92e-269 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
EPEFKAOO_00658 2.24e-196 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
EPEFKAOO_00659 2.05e-185 yycI - - S - - - YycH protein
EPEFKAOO_00660 4.23e-305 yycH - - S - - - YycH protein
EPEFKAOO_00661 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EPEFKAOO_00662 3.69e-168 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
EPEFKAOO_00665 8.32e-66 - - - - - - - -
EPEFKAOO_00666 7.6e-269 - - - E - - - Major Facilitator Superfamily
EPEFKAOO_00667 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
EPEFKAOO_00668 2.63e-99 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
EPEFKAOO_00669 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
EPEFKAOO_00670 1.33e-47 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EPEFKAOO_00671 6.56e-165 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
EPEFKAOO_00672 6.02e-64 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
EPEFKAOO_00673 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EPEFKAOO_00674 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EPEFKAOO_00675 1.06e-259 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EPEFKAOO_00676 1.45e-46 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain protein YaaA
EPEFKAOO_00677 3.2e-264 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
EPEFKAOO_00678 9.49e-317 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EPEFKAOO_00680 7.96e-21 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
EPEFKAOO_00681 2.64e-75 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
EPEFKAOO_00682 4.99e-187 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EPEFKAOO_00683 1.83e-198 jag - - S ko:K06346 - ko00000 R3H domain protein
EPEFKAOO_00684 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EPEFKAOO_00685 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
EPEFKAOO_00686 1.2e-74 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
EPEFKAOO_00687 4.35e-284 lysP - - E ko:K03293,ko:K11733 - ko00000,ko02000 amino acid
EPEFKAOO_00688 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
EPEFKAOO_00689 0.0 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EPEFKAOO_00690 0.0 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EPEFKAOO_00691 1.16e-146 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
EPEFKAOO_00692 3.08e-209 - - - F ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
EPEFKAOO_00693 2.76e-109 - - - L - - - nuclease
EPEFKAOO_00694 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EPEFKAOO_00695 3.85e-68 - - - - - - - -
EPEFKAOO_00696 0.0 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
EPEFKAOO_00697 1.58e-240 - - - E - - - Zinc-binding dehydrogenase
EPEFKAOO_00698 6.45e-138 - - - K - - - Bacterial regulatory proteins, tetR family
EPEFKAOO_00699 1.65e-208 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
EPEFKAOO_00700 1.96e-156 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EPEFKAOO_00701 7.5e-100 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
EPEFKAOO_00702 3.55e-61 czrA - - K ko:K22043 - ko00000,ko03000 Transcriptional regulator, ArsR family
EPEFKAOO_00703 7.65e-314 - 3.2.1.17 CBM50 NU ko:K01185,ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
EPEFKAOO_00704 5.8e-216 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional regulator, LacI family
EPEFKAOO_00705 3.19e-35 - - - - - - - -
EPEFKAOO_00706 9.74e-138 - - - - - - - -
EPEFKAOO_00707 6.55e-126 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EPEFKAOO_00708 3.55e-139 nnrE 5.1.99.6 - H ko:K17759 - ko00000,ko01000 Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
EPEFKAOO_00709 9.87e-70 - - - - - - - -
EPEFKAOO_00710 9.06e-159 yrkL - - S - - - Flavodoxin-like fold
EPEFKAOO_00712 1.36e-85 yeaO - - S - - - Protein of unknown function, DUF488
EPEFKAOO_00713 1.64e-149 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
EPEFKAOO_00714 4.5e-260 - - - S - - - associated with various cellular activities
EPEFKAOO_00715 2.61e-272 - - - S - - - Putative metallopeptidase domain
EPEFKAOO_00716 8.5e-61 - - - - - - - -
EPEFKAOO_00717 3e-291 pbuG - - S ko:K06901 - ko00000,ko02000 permease
EPEFKAOO_00718 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
EPEFKAOO_00719 2.44e-120 ymdB - - S - - - Macro domain protein
EPEFKAOO_00720 8.79e-188 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
EPEFKAOO_00721 4.43e-105 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
EPEFKAOO_00722 7.31e-218 - 1.1.1.399, 1.1.1.95 - CH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EPEFKAOO_00723 9.08e-71 - - - - - - - -
EPEFKAOO_00724 1.09e-180 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
EPEFKAOO_00725 1.81e-156 - - - U ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
EPEFKAOO_00726 2.05e-174 - - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
EPEFKAOO_00727 1.21e-48 - - - - - - - -
EPEFKAOO_00728 2.44e-125 - - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
EPEFKAOO_00729 8.66e-188 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
EPEFKAOO_00730 1.2e-234 celE3 - - E - - - GDSL-like Lipase/Acylhydrolase family
EPEFKAOO_00731 8.83e-287 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EPEFKAOO_00732 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
EPEFKAOO_00733 3.16e-234 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
EPEFKAOO_00734 9.45e-140 - - - L ko:K07497 - ko00000 hmm pf00665
EPEFKAOO_00735 2.09e-78 - - - L - - - Helix-turn-helix domain
EPEFKAOO_00736 0.0 rafA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
EPEFKAOO_00737 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
EPEFKAOO_00738 2.01e-72 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NLP P60 protein
EPEFKAOO_00739 4.14e-09 - - - - - - - -
EPEFKAOO_00740 1.89e-203 yfdH - GT2 M ko:K12999 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
EPEFKAOO_00741 2.43e-218 yueF - - S - - - AI-2E family transporter
EPEFKAOO_00742 2.97e-34 - - - S - - - Psort location CytoplasmicMembrane, score
EPEFKAOO_00743 6.32e-211 ykoT - - M - - - Glycosyl transferase family 2
EPEFKAOO_00744 1.62e-239 - - - S - - - Psort location CytoplasmicMembrane, score
EPEFKAOO_00745 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EPEFKAOO_00746 2.77e-94 - - - S - - - Bacterial membrane protein, YfhO
EPEFKAOO_00747 1.4e-26 - - - S - - - Glycosyltransferase like family 2
EPEFKAOO_00748 2.03e-130 - - - M - - - Dolichyl-phosphate-mannose-protein mannosyltransferase
EPEFKAOO_00749 2.09e-216 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
EPEFKAOO_00750 2.08e-84 - - - K - - - Transcriptional regulator, GntR family
EPEFKAOO_00751 5.71e-202 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EPEFKAOO_00754 6.84e-315 yxbA 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp enzyme
EPEFKAOO_00755 4.44e-208 - - - EG - - - EamA-like transporter family
EPEFKAOO_00756 4.07e-174 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EPEFKAOO_00757 9.48e-182 - - - G - - - MucBP domain
EPEFKAOO_00758 8.07e-126 - - - S - - - Pfam:DUF3816
EPEFKAOO_00759 0.0 nadC2 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EPEFKAOO_00760 4.98e-142 pncA - - Q - - - Isochorismatase family
EPEFKAOO_00761 3.54e-166 - - - F - - - NUDIX domain
EPEFKAOO_00762 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
EPEFKAOO_00763 2.41e-07 - - - - - - - -
EPEFKAOO_00764 8.72e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
EPEFKAOO_00765 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EPEFKAOO_00766 5.62e-294 pimB 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
EPEFKAOO_00767 8.99e-254 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
EPEFKAOO_00768 9.75e-232 mprF - - I ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EPEFKAOO_00769 2.81e-53 - - - S - - - Protein of unknown function (DUF1797)
EPEFKAOO_00770 3.87e-80 - - - - - - - -
EPEFKAOO_00771 1.41e-243 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
EPEFKAOO_00772 3.09e-90 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EPEFKAOO_00773 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
EPEFKAOO_00774 4.05e-266 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
EPEFKAOO_00775 1.46e-71 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EPEFKAOO_00776 5.77e-11 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
EPEFKAOO_00777 4.27e-62 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
EPEFKAOO_00778 2.55e-215 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Histidinol phosphate phosphatase, HisJ
EPEFKAOO_00779 7.44e-278 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EPEFKAOO_00780 3.18e-140 hisG 2.4.2.17 - F ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
EPEFKAOO_00781 1.56e-293 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EPEFKAOO_00782 1.86e-134 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
EPEFKAOO_00783 1.21e-143 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EPEFKAOO_00784 3.39e-167 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EPEFKAOO_00785 5.43e-183 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
EPEFKAOO_00786 1.12e-74 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EPEFKAOO_00787 2.63e-69 hisE 3.6.1.31 - E ko:K01523 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 phosphoribosyl-ATP diphosphatase activity
EPEFKAOO_00788 1.28e-254 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EPEFKAOO_00789 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
EPEFKAOO_00791 7.51e-145 pgm1 - - G - - - phosphoglycerate mutase
EPEFKAOO_00792 5.69e-140 - - - C - - - aldo keto reductase
EPEFKAOO_00793 5.06e-259 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EPEFKAOO_00794 7.22e-283 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EPEFKAOO_00795 0.0 - - - K - - - COG COG0846 NAD-dependent protein deacetylases, SIR2 family
EPEFKAOO_00796 2.35e-104 - - - K - - - 2 iron, 2 sulfur cluster binding
EPEFKAOO_00797 1.14e-105 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
EPEFKAOO_00798 1.12e-289 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
EPEFKAOO_00799 1.52e-137 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
EPEFKAOO_00800 1.19e-259 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EPEFKAOO_00801 4.59e-49 - - - C - - - Flavodoxin
EPEFKAOO_00802 1.32e-75 - - - T - - - His Kinase A (phosphoacceptor) domain
EPEFKAOO_00803 2.06e-66 - - - T - - - Transcriptional regulatory protein, C terminal
EPEFKAOO_00804 7.21e-18 - - - S - - - ABC-type transport system involved in multi-copper enzyme maturation permease component
EPEFKAOO_00806 4.41e-215 - - - L - - - PFAM Integrase catalytic region
EPEFKAOO_00807 1.53e-30 - - - L ko:K07483,ko:K09936 ko02024,map02024 ko00000,ko00001,ko02000 Helix-turn-helix domain
EPEFKAOO_00810 6.8e-62 - - - L - - - Protein of unknown function (DUF3991)
EPEFKAOO_00811 4.79e-167 topA2 5.99.1.2 - G ko:K03169 - ko00000,ko01000,ko03032 Topoisomerase IA
EPEFKAOO_00814 8.97e-177 - - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
EPEFKAOO_00818 1.09e-267 - - - U ko:K03205 ko03070,map03070 ko00000,ko00001,ko00002,ko02044 TraM recognition site of TraD and TraG
EPEFKAOO_00819 6.75e-75 - - - - - - - -
EPEFKAOO_00824 1.63e-43 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
EPEFKAOO_00827 3.55e-28 - - - - - - - -
EPEFKAOO_00828 3.17e-230 - - - U - - - type IV secretory pathway VirB4
EPEFKAOO_00830 2.33e-33 - - - M - - - CHAP domain
EPEFKAOO_00834 3.34e-07 ydiL - - S ko:K07052 - ko00000 protease
EPEFKAOO_00835 1.68e-19 - - - - ko:K18640 - ko00000,ko04812 -
EPEFKAOO_00838 1.08e-39 - - - V - - - N-6 DNA Methylase
EPEFKAOO_00839 1.19e-80 nhaK - - P ko:K03316 - ko00000 Sodium proton antiporter
EPEFKAOO_00840 1.01e-99 - - - - - - - -
EPEFKAOO_00841 6.16e-235 - - - - - - - -
EPEFKAOO_00842 2.6e-165 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase
EPEFKAOO_00843 2.15e-132 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 Nitrate reductase delta subunit
EPEFKAOO_00844 0.0 - 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 4Fe-4S dicluster domain
EPEFKAOO_00845 0.0 narZ 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EPEFKAOO_00846 2.96e-242 moeB 2.7.7.80 - H ko:K21029 ko04122,map04122 ko00000,ko00001,ko01000 ThiF family
EPEFKAOO_00847 6.25e-112 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
EPEFKAOO_00848 2.58e-294 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 MoeA N-terminal region (domain I and II)
EPEFKAOO_00849 3.88e-108 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
EPEFKAOO_00850 5.64e-125 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
EPEFKAOO_00851 6.94e-54 - - - - - - - -
EPEFKAOO_00852 1.43e-100 nreA - - T ko:K10851 ko02020,map02020 ko00000,ko00001 GAF domain
EPEFKAOO_00853 2.68e-236 nreB 2.7.13.3 - F ko:K07683 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Sensor histidine kinase
EPEFKAOO_00854 4.49e-151 nreC - - K ko:K07696 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 PFAM regulatory protein LuxR
EPEFKAOO_00855 1.99e-53 - - - - - - - -
EPEFKAOO_00856 8.42e-236 - - - - - - - -
EPEFKAOO_00857 3.49e-217 - - - H - - - geranyltranstransferase activity
EPEFKAOO_00859 7.17e-172 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
EPEFKAOO_00860 5.52e-209 - - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
EPEFKAOO_00861 2.36e-77 - - - S - - - Iron-sulfur cluster assembly protein
EPEFKAOO_00862 2.31e-278 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 Major Facilitator Superfamily
EPEFKAOO_00863 3.36e-249 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EPEFKAOO_00864 6.72e-47 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 ThiS family
EPEFKAOO_00865 7.91e-95 moaE 2.8.1.12 - H ko:K03635,ko:K21142 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 MoaE protein
EPEFKAOO_00866 6.93e-217 fecD - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EPEFKAOO_00867 4.31e-182 fecE 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
EPEFKAOO_00868 7.35e-291 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
EPEFKAOO_00869 3.62e-72 yitW - - S - - - Iron-sulfur cluster assembly protein
EPEFKAOO_00870 4.24e-26 - - - S - - - Domain of unknown function (DUF1858)
EPEFKAOO_00871 0.0 XK27_04775 - - S ko:K09155 - ko00000 PAS domain
EPEFKAOO_00872 1.12e-181 - - - EG - - - EamA-like transporter family
EPEFKAOO_00873 8.12e-106 - - - S - - - Bacterial transferase hexapeptide (six repeats)
EPEFKAOO_00874 1.13e-152 - - - IQ - - - Enoyl-(Acyl carrier protein) reductase
EPEFKAOO_00875 6.09e-254 gldA 1.1.1.6 - C ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 ko00000,ko00001,ko01000 dehydrogenase
EPEFKAOO_00876 6.96e-13 - - - K - - - transcriptional
EPEFKAOO_00877 1.56e-67 - - - S - - - Sugar efflux transporter for intercellular exchange
EPEFKAOO_00878 1.75e-73 - - - S - - - Antibiotic biosynthesis monooxygenase
EPEFKAOO_00879 2.4e-58 - - - S - - - Protein conserved in bacteria
EPEFKAOO_00880 4.71e-126 ydeQ - - S ko:K11748 - ko00000,ko02000 Flavodoxin-like fold
EPEFKAOO_00881 1.06e-193 mhpD - - Q ko:K02509 ko00350,ko01120,map00350,map01120 ko00000,ko00001,ko01000 hydratase
EPEFKAOO_00882 7.82e-239 ldhA 1.1.1.28 - C ko:K03778,ko:K18347 ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01504 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EPEFKAOO_00883 6.96e-83 - - - S - - - Domain of unknown function (DUF4440)
EPEFKAOO_00884 2.41e-123 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EPEFKAOO_00885 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
EPEFKAOO_00886 1.3e-199 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
EPEFKAOO_00887 4.11e-223 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
EPEFKAOO_00888 1.91e-316 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EPEFKAOO_00889 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
EPEFKAOO_00890 3.97e-174 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
EPEFKAOO_00892 5.48e-70 - - - S - - - mazG nucleotide pyrophosphohydrolase
EPEFKAOO_00893 4.39e-139 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
EPEFKAOO_00894 2.06e-297 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EPEFKAOO_00895 1.15e-299 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
EPEFKAOO_00896 4.94e-288 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EPEFKAOO_00897 9.45e-208 - - - S - - - Tetratricopeptide repeat
EPEFKAOO_00898 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EPEFKAOO_00899 2.92e-44 gshAB 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
EPEFKAOO_00900 0.0 - - - S - - - amidohydrolase
EPEFKAOO_00901 1.08e-218 hdhL 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
EPEFKAOO_00902 4.51e-156 pgm6 - - G - - - phosphoglycerate mutase
EPEFKAOO_00903 9.37e-159 - - - S - - - repeat protein
EPEFKAOO_00904 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
EPEFKAOO_00905 6.59e-229 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EPEFKAOO_00906 2.39e-98 - - - P - - - ArsC family
EPEFKAOO_00907 2.53e-240 - - - I - - - Diacylglycerol kinase catalytic
EPEFKAOO_00908 8.83e-43 ykzG - - S - - - Belongs to the UPF0356 family
EPEFKAOO_00909 6.12e-98 - - - - - - - -
EPEFKAOO_00910 8.59e-133 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
EPEFKAOO_00911 1.55e-65 yktA - - S - - - Belongs to the UPF0223 family
EPEFKAOO_00912 8e-177 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the inositol monophosphatase superfamily
EPEFKAOO_00913 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
EPEFKAOO_00914 2.79e-275 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
EPEFKAOO_00915 1.31e-63 ylbG - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
EPEFKAOO_00916 5.18e-128 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
EPEFKAOO_00917 2.51e-115 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EPEFKAOO_00918 1.38e-252 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
EPEFKAOO_00919 1.47e-127 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
EPEFKAOO_00920 8.66e-116 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
EPEFKAOO_00921 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
EPEFKAOO_00922 1.63e-236 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
EPEFKAOO_00923 5.38e-158 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
EPEFKAOO_00924 7.41e-61 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EPEFKAOO_00925 6.76e-119 lemA - - S ko:K03744 - ko00000 LemA family
EPEFKAOO_00926 1.34e-202 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
EPEFKAOO_00927 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
EPEFKAOO_00928 0.0 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
EPEFKAOO_00929 1.18e-78 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
EPEFKAOO_00930 8.5e-266 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EPEFKAOO_00931 7.09e-75 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
EPEFKAOO_00932 6.41e-148 - - - S - - - (CBS) domain
EPEFKAOO_00933 7.98e-132 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
EPEFKAOO_00934 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EPEFKAOO_00935 2.47e-53 yabO - - J - - - S4 domain protein
EPEFKAOO_00936 5.88e-74 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
EPEFKAOO_00937 1.65e-113 yabR - - J ko:K07571 - ko00000 RNA binding
EPEFKAOO_00938 0.0 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
EPEFKAOO_00939 5.21e-126 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
EPEFKAOO_00940 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EPEFKAOO_00941 3.89e-208 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EPEFKAOO_00942 2.64e-242 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EPEFKAOO_00943 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
EPEFKAOO_00944 8.59e-293 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
EPEFKAOO_00945 1.16e-32 - - - K - - - transcriptional regulator
EPEFKAOO_00946 1.71e-224 ydbI - - K - - - AI-2E family transporter
EPEFKAOO_00947 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
EPEFKAOO_00948 4.78e-105 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EPEFKAOO_00949 7.13e-277 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EPEFKAOO_00950 0.0 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EPEFKAOO_00951 2.06e-223 hrpQ 4.6.1.1 - T ko:K01768,ko:K03220,ko:K10914 ko00230,ko02020,ko02024,ko02025,ko02026,ko04113,ko04213,ko05111,map00230,map02020,map02024,map02025,map02026,map04113,map04213,map05111 ko00000,ko00001,ko00002,ko01000,ko02044,ko03000 histone H2A K63-linked ubiquitination
EPEFKAOO_00952 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
EPEFKAOO_00953 1.1e-14 nagZ 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Glycosyl hydrolase family 3 N terminal domain
EPEFKAOO_00954 6.13e-174 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
EPEFKAOO_00955 1.36e-50 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EPEFKAOO_00956 4.87e-164 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EPEFKAOO_00957 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EPEFKAOO_00958 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EPEFKAOO_00959 4.8e-251 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
EPEFKAOO_00960 1.13e-139 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EPEFKAOO_00961 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
EPEFKAOO_00962 2.36e-308 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
EPEFKAOO_00963 4.5e-12 - - - S - - - Protein of unknown function (DUF4044)
EPEFKAOO_00964 6.91e-76 - - - - - - - -
EPEFKAOO_00965 3.65e-102 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
EPEFKAOO_00966 5.37e-221 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
EPEFKAOO_00967 3.49e-29 ftsL - - D - - - Cell division protein FtsL
EPEFKAOO_00968 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
EPEFKAOO_00969 4.46e-227 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EPEFKAOO_00970 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EPEFKAOO_00971 2.06e-259 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EPEFKAOO_00972 5.43e-193 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
EPEFKAOO_00973 4.88e-300 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
EPEFKAOO_00974 1.82e-293 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EPEFKAOO_00975 1.5e-101 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
EPEFKAOO_00976 7.27e-56 ylmG - - S ko:K02221 - ko00000,ko02044 YGGT family
EPEFKAOO_00977 1.24e-186 ylmH - - S - - - S4 domain protein
EPEFKAOO_00978 6.19e-143 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
EPEFKAOO_00980 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EPEFKAOO_00981 9.99e-44 cspB - - K ko:K03704 - ko00000,ko03000 Cold shock protein
EPEFKAOO_00982 1.28e-126 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
EPEFKAOO_00983 9.41e-09 - - - - - - - -
EPEFKAOO_00984 3.96e-163 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EPEFKAOO_00985 7.86e-77 XK27_04120 - - S - - - Putative amino acid metabolism
EPEFKAOO_00986 4e-282 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
EPEFKAOO_00987 6.97e-204 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
EPEFKAOO_00988 3.2e-301 proP - - EGP ko:K03761,ko:K03762 - ko00000,ko02000 Sugar (and other) transporter
EPEFKAOO_00989 3.01e-179 - 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
EPEFKAOO_00990 7.35e-200 isdF - - U ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EPEFKAOO_00991 1.88e-194 isdE - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
EPEFKAOO_00992 3.24e-130 - - - M ko:K14193 ko05150,map05150 ko00000,ko00001 Iron Transport-associated domain
EPEFKAOO_00993 0.0 - - - M - - - Iron Transport-associated domain
EPEFKAOO_00994 1.91e-104 - - - - - - - -
EPEFKAOO_00995 4.25e-71 - 4.1.1.44 - O ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EPEFKAOO_00996 1.69e-41 ydzE - - EG - - - spore germination
EPEFKAOO_00997 8.24e-116 - - - P - - - Cadmium resistance transporter
EPEFKAOO_00998 5.91e-36 - - - C - - - Aldo/keto reductase family
EPEFKAOO_01000 4.15e-05 - - - S - - - CsbD-like
EPEFKAOO_01001 2.07e-58 - - - C - - - Aldo keto reductase
EPEFKAOO_01003 5.7e-56 - - - K - - - Bacterial regulatory helix-turn-helix protein, lysR family
EPEFKAOO_01005 2.78e-132 - 3.8.1.5 - S ko:K01563 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Alpha/beta hydrolase family
EPEFKAOO_01006 3.17e-156 pnb - - C - - - nitroreductase
EPEFKAOO_01007 1.33e-57 yodA - - S - - - Tautomerase enzyme
EPEFKAOO_01008 2.22e-36 - - - S - - - Domain of unknown function (DUF4767)
EPEFKAOO_01009 3.43e-280 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
EPEFKAOO_01010 1.26e-268 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Cys/Met metabolism PLP-dependent enzyme
EPEFKAOO_01012 6.31e-78 yxeM - - ET ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
EPEFKAOO_01013 2.07e-59 yxeL - - K - - - acetyltransferase
EPEFKAOO_01014 6.91e-98 yxeN - - U ko:K02029,ko:K16959,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, permease protein
EPEFKAOO_01015 2.15e-100 yxeO - - E ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
EPEFKAOO_01016 8.5e-185 hipO2 - - E ko:K01436,ko:K21613 - ko00000,ko01000,ko01002 Peptidase dimerisation domain
EPEFKAOO_01017 5.14e-215 - 4.3.2.2, 5.5.1.2 - F ko:K01756,ko:K01857 ko00230,ko00250,ko00362,ko01100,ko01110,ko01120,ko01130,ko01220,map00230,map00250,map00362,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko00002,ko01000 Adenylosuccinate lyase C-terminus
EPEFKAOO_01018 1.53e-108 - - - S - - - MmgE/PrpD family
EPEFKAOO_01020 9.72e-147 glnP9 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter, permease protein
EPEFKAOO_01021 2.66e-146 glnP7 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter permease
EPEFKAOO_01022 1.19e-174 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
EPEFKAOO_01023 7.45e-197 cjaA - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
EPEFKAOO_01024 1.1e-175 - - - IQ - - - KR domain
EPEFKAOO_01025 2.75e-269 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Homoserine dehydrogenase
EPEFKAOO_01026 6.45e-202 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
EPEFKAOO_01027 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
EPEFKAOO_01028 1.95e-221 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine S-methyltransferase
EPEFKAOO_01029 7.92e-217 - - - G - - - Phosphotransferase enzyme family
EPEFKAOO_01030 5.41e-227 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Ami_3
EPEFKAOO_01031 8.94e-250 - 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
EPEFKAOO_01032 1.39e-314 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
EPEFKAOO_01033 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
EPEFKAOO_01034 4.5e-165 - - - F - - - glutamine amidotransferase
EPEFKAOO_01035 3.81e-31 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
EPEFKAOO_01036 3.07e-93 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
EPEFKAOO_01037 1.75e-228 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
EPEFKAOO_01038 2.91e-104 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EPEFKAOO_01039 7.64e-88 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
EPEFKAOO_01040 8.91e-218 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EPEFKAOO_01041 3.43e-196 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
EPEFKAOO_01042 2.95e-239 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
EPEFKAOO_01043 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
EPEFKAOO_01044 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
EPEFKAOO_01045 1.21e-264 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
EPEFKAOO_01046 9.2e-58 - - - IQ - - - Enoyl-(Acyl carrier protein) reductase
EPEFKAOO_01047 1.53e-52 - - - IQ - - - Enoyl-(Acyl carrier protein) reductase
EPEFKAOO_01048 1.27e-164 - - - EGP - - - Major Facilitator
EPEFKAOO_01049 1.42e-215 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
EPEFKAOO_01050 7.15e-232 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EPEFKAOO_01051 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
EPEFKAOO_01052 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
EPEFKAOO_01053 6.39e-115 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
EPEFKAOO_01054 6.07e-277 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
EPEFKAOO_01055 1.88e-224 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EPEFKAOO_01056 4.65e-183 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
EPEFKAOO_01057 1.14e-276 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
EPEFKAOO_01058 1.28e-253 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EPEFKAOO_01059 4.8e-293 ktrB - - P ko:K03498 - ko00000,ko02000 Potassium uptake protein
EPEFKAOO_01060 3.26e-152 ktrA - - P ko:K03499 - ko00000,ko02000 domain protein
EPEFKAOO_01061 8.01e-162 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
EPEFKAOO_01062 1.64e-199 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EPEFKAOO_01063 2.52e-301 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
EPEFKAOO_01065 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
EPEFKAOO_01066 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
EPEFKAOO_01067 3.62e-214 yitL - - S ko:K00243 - ko00000 S1 domain
EPEFKAOO_01068 2.98e-175 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
EPEFKAOO_01069 2.23e-89 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EPEFKAOO_01070 1.18e-182 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EPEFKAOO_01071 3.2e-131 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EPEFKAOO_01072 1.38e-166 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
EPEFKAOO_01073 2.87e-101 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EPEFKAOO_01074 1.34e-254 - - - S - - - Helix-turn-helix domain
EPEFKAOO_01075 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
EPEFKAOO_01076 4.37e-76 - - - M - - - Lysin motif
EPEFKAOO_01077 3.8e-152 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
EPEFKAOO_01078 4.63e-275 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
EPEFKAOO_01079 1.5e-312 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
EPEFKAOO_01080 2.65e-53 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
EPEFKAOO_01081 5.08e-300 XK27_05225 - - S - - - Tetratricopeptide repeat protein
EPEFKAOO_01082 1.29e-211 - - - L - - - Phage integrase, N-terminal SAM-like domain
EPEFKAOO_01083 1.86e-285 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
EPEFKAOO_01084 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 ABC transporter, ATP-binding protein
EPEFKAOO_01085 5.32e-244 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EPEFKAOO_01086 3.62e-121 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EPEFKAOO_01087 8.06e-141 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
EPEFKAOO_01088 4.49e-196 WQ51_01275 - - S - - - EDD domain protein, DegV family
EPEFKAOO_01089 4.64e-275 - 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 D-isomer specific 2-hydroxyacid dehydrogenase
EPEFKAOO_01090 1.15e-144 cat 2.3.1.79 - S ko:K00661,ko:K18234 - ko00000,ko01000,ko01504 Bacterial transferase hexapeptide (six repeats)
EPEFKAOO_01091 2.02e-216 - - - E - - - lipolytic protein G-D-S-L family
EPEFKAOO_01092 2.85e-135 ypmS - - S - - - Uncharacterized protein conserved in bacteria (DUF2140)
EPEFKAOO_01093 2.1e-49 yozE - - S - - - Belongs to the UPF0346 family
EPEFKAOO_01094 1.78e-207 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EPEFKAOO_01095 8.69e-182 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EPEFKAOO_01096 7.3e-212 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
EPEFKAOO_01097 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EPEFKAOO_01098 2.24e-198 - - - D - - - DNA integration
EPEFKAOO_01099 9.3e-220 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
EPEFKAOO_01100 5.26e-134 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
EPEFKAOO_01101 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
EPEFKAOO_01102 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
EPEFKAOO_01103 2.53e-123 - - - S ko:K08996 - ko00000 Protein of unknown function (DUF1440)
EPEFKAOO_01104 4.6e-220 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
EPEFKAOO_01105 7.86e-92 - - - S - - - Belongs to the HesB IscA family
EPEFKAOO_01106 4.65e-100 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
EPEFKAOO_01107 3.6e-122 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
EPEFKAOO_01108 5.48e-106 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
EPEFKAOO_01109 2.93e-313 - - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
EPEFKAOO_01110 3.75e-307 codA 3.5.4.1 - F ko:K01485 ko00240,ko00330,ko01100,map00240,map00330,map01100 ko00000,ko00001,ko01000 cytosine deaminase
EPEFKAOO_01111 0.0 - - - EP - - - Psort location Cytoplasmic, score
EPEFKAOO_01113 0.0 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
EPEFKAOO_01114 3.26e-153 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
EPEFKAOO_01115 5.01e-311 yhjX - - P ko:K08177 - ko00000,ko02000 Major Facilitator Superfamily
EPEFKAOO_01117 1.89e-22 ycnB - - U - - - Belongs to the major facilitator superfamily
EPEFKAOO_01118 3.76e-145 eriC - - P ko:K03281 - ko00000 chloride
EPEFKAOO_01119 6.4e-197 - - - C - - - NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain
EPEFKAOO_01120 1.02e-153 - - - M - - - racemase activity, acting on amino acids and derivatives
EPEFKAOO_01121 3.47e-76 - - - E ko:K03758 - ko00000,ko02000 Amino acid permease
EPEFKAOO_01122 6.49e-226 - - - E ko:K03758 - ko00000,ko02000 Amino acid permease
EPEFKAOO_01123 5.43e-256 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
EPEFKAOO_01124 4.27e-138 lacA 2.3.1.18, 2.3.1.79 - S ko:K00633,ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
EPEFKAOO_01125 7.55e-110 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
EPEFKAOO_01126 3.32e-119 - - - S - - - Fic/DOC family
EPEFKAOO_01127 4.87e-115 - 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Phosphoribosyl transferase domain
EPEFKAOO_01128 7.6e-123 - - - EGP ko:K08368 - ko00000,ko02000 Sugar (and other) transporter
EPEFKAOO_01129 6e-172 - - - EGP ko:K08368 - ko00000,ko02000 Sugar (and other) transporter
EPEFKAOO_01130 4.38e-106 - 4.3.1.12 - E ko:K01750 ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230 ko00000,ko00001,ko01000 Ornithine cyclodeaminase/mu-crystallin family
EPEFKAOO_01131 1.77e-109 - 4.3.1.12 - E ko:K01750 ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230 ko00000,ko00001,ko01000 Ornithine cyclodeaminase/mu-crystallin family
EPEFKAOO_01132 8.61e-273 - - - E - - - Aminotransferase
EPEFKAOO_01135 4.74e-159 - - - S - - - Phage minor capsid protein 2
EPEFKAOO_01136 2.21e-210 - - - I - - - alpha/beta hydrolase fold
EPEFKAOO_01137 1.35e-124 - 2.3.1.128 - K ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
EPEFKAOO_01139 3.82e-204 - - - S - - - DUF218 domain
EPEFKAOO_01140 1.14e-213 yvgN - - C - - - Aldo keto reductase
EPEFKAOO_01141 1.85e-105 - - - S - - - ECF-type riboflavin transporter, S component
EPEFKAOO_01142 1.57e-194 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
EPEFKAOO_01143 1.4e-300 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 Isocitrate/isopropylmalate dehydrogenase
EPEFKAOO_01144 1.28e-89 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
EPEFKAOO_01145 6.9e-258 xerS - - L ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family
EPEFKAOO_01146 5.65e-229 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
EPEFKAOO_01147 2.44e-286 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
EPEFKAOO_01148 4.1e-250 bdhA 1.1.1.14, 1.1.1.264, 1.1.1.303, 1.1.1.4 - C ko:K00004,ko:K00008,ko:K00098 ko00040,ko00051,ko00650,ko01100,map00040,map00051,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Zinc-binding dehydrogenase
EPEFKAOO_01149 1.74e-108 - - - C - - - Zinc-binding dehydrogenase
EPEFKAOO_01150 0.0 - 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Thioredoxin domain
EPEFKAOO_01151 1.88e-135 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Peroxiredoxin
EPEFKAOO_01152 2.07e-281 - - - G - - - Major Facilitator
EPEFKAOO_01153 0.0 - 3.2.1.37 GH43 G ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
EPEFKAOO_01154 1.71e-104 - - - K - - - helix_turn_helix, arabinose operon control protein
EPEFKAOO_01155 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Xylulose kinase
EPEFKAOO_01156 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
EPEFKAOO_01157 0.0 xylT - - EGP - - - Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
EPEFKAOO_01158 5.21e-275 xylR - - GK - - - ROK family
EPEFKAOO_01159 1.18e-194 - - - U ko:K05340 - ko00000,ko02000 sugar transport
EPEFKAOO_01160 0.0 yclK - - T - - - Histidine kinase
EPEFKAOO_01161 1.89e-168 yclJ - - K ko:K02483 - ko00000,ko02022 response regulator
EPEFKAOO_01163 4.28e-178 budC 1.1.1.304, 1.1.1.76 - IQ ko:K03366 ko00650,map00650 ko00000,ko00001,ko01000 reductase
EPEFKAOO_01164 9.5e-142 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
EPEFKAOO_01165 9.56e-133 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
EPEFKAOO_01166 3.55e-278 purK2 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EPEFKAOO_01167 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
EPEFKAOO_01168 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EPEFKAOO_01169 7.07e-236 camS - - S - - - sex pheromone
EPEFKAOO_01170 1.71e-65 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EPEFKAOO_01171 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
EPEFKAOO_01172 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EPEFKAOO_01173 2.63e-239 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
EPEFKAOO_01174 0.0 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EPEFKAOO_01175 7.83e-65 - - - K - - - TRANSCRIPTIONal
EPEFKAOO_01176 2.48e-62 - - - L ko:K07483 - ko00000 Transposase
EPEFKAOO_01177 1.14e-81 - - - M - - - Glycosyl transferase 4-like
EPEFKAOO_01178 8.8e-116 capM - - M ko:K13012 - ko00000,ko01005 Bacterial sugar transferase
EPEFKAOO_01179 4.63e-177 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
EPEFKAOO_01180 3.9e-146 ywqD - - D - - - Capsular exopolysaccharide family
EPEFKAOO_01181 5.79e-171 epsB - - M - - - biosynthesis protein
EPEFKAOO_01182 2.01e-221 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
EPEFKAOO_01183 1.71e-264 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
EPEFKAOO_01184 9.67e-175 - - - S - - - Protein of unknown function (DUF1129)
EPEFKAOO_01185 2.13e-255 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
EPEFKAOO_01186 1.26e-42 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
EPEFKAOO_01187 4.35e-188 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
EPEFKAOO_01188 5.7e-210 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
EPEFKAOO_01189 1.01e-170 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
EPEFKAOO_01190 2.31e-185 rihA 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
EPEFKAOO_01191 6.29e-272 nupG - - F ko:K03317,ko:K11535,ko:K16323 - ko00000,ko02000 Nucleoside transporter
EPEFKAOO_01192 1.44e-50 potE - - E - - - Amino Acid
EPEFKAOO_01193 1.65e-281 potE - - E - - - Amino Acid
EPEFKAOO_01194 8.17e-242 - - - K ko:K02525 - ko00000,ko03000 helix_turn _helix lactose operon repressor
EPEFKAOO_01195 0.0 - - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system Galactitol-specific IIC component
EPEFKAOO_01196 1.05e-223 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EPEFKAOO_01197 4.28e-255 - - - S - - - Domain of unknown function (DUF4432)
EPEFKAOO_01198 2.39e-146 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EPEFKAOO_01199 1.42e-218 deoR - - K ko:K05346 - ko00000,ko03000 sugar-binding domain protein
EPEFKAOO_01200 7.55e-212 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EPEFKAOO_01201 8.61e-89 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
EPEFKAOO_01202 0.0 fucP - - G ko:K02429 - ko00000,ko02000 Major Facilitator Superfamily
EPEFKAOO_01203 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EPEFKAOO_01223 1.12e-90 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
EPEFKAOO_01224 8.81e-152 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
EPEFKAOO_01225 2.06e-263 coiA - - S ko:K06198 - ko00000 Competence protein
EPEFKAOO_01226 1.46e-147 yjbH - - Q - - - Thioredoxin
EPEFKAOO_01227 5.24e-159 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
EPEFKAOO_01228 9.49e-197 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EPEFKAOO_01229 5.39e-221 yjbO 5.4.99.23 - G ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
EPEFKAOO_01230 9.32e-252 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
EPEFKAOO_01231 6.46e-207 rrmA 2.1.1.187 - H ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 Methyltransferase
EPEFKAOO_01232 2.01e-123 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
EPEFKAOO_01233 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
EPEFKAOO_01234 1.55e-157 - - - - - - - -
EPEFKAOO_01235 1.4e-207 ybhF_1 - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
EPEFKAOO_01236 0.0 - - - M ko:K01992 - ko00000,ko00002,ko02000 Exporter of polyketide antibiotics
EPEFKAOO_01237 2.94e-148 - - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
EPEFKAOO_01238 9.52e-128 pinR1 - - L - - - Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
EPEFKAOO_01239 4.86e-199 cylA - - V ko:K11050 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
EPEFKAOO_01240 5.82e-188 cylB - - V ko:K11051 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 type transporter
EPEFKAOO_01241 2.48e-52 - - - L ko:K07483 - ko00000 Transposase and inactivated derivatives
EPEFKAOO_01242 7.63e-180 is18 - - L - - - Integrase core domain
EPEFKAOO_01243 7.92e-193 rbn - - S ko:K07058 - ko00000 Virulence factor BrkB
EPEFKAOO_01244 3.45e-91 - - - S - - - Nuclease-related domain
EPEFKAOO_01245 7.82e-114 - - - - - - - -
EPEFKAOO_01246 1.95e-95 asp1 - - S - - - Asp23 family, cell envelope-related function
EPEFKAOO_01247 4.86e-41 - - - S - - - Transglycosylase associated protein
EPEFKAOO_01248 4.74e-23 - - - - - - - -
EPEFKAOO_01249 6.89e-27 yitW - - S - - - Iron-sulfur cluster assembly protein
EPEFKAOO_01250 1.24e-132 - 4.2.1.2, 4.2.1.32 - C ko:K01676,ko:K03780 ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible hydration of fumarate to (S)- malate
EPEFKAOO_01251 2.15e-211 ttdA 4.2.1.32 - C ko:K03779 ko00630,map00630 ko00000,ko00001,ko01000 Fumarate hydratase (Fumerase)
EPEFKAOO_01252 2.4e-159 - - - K - - - Helix-turn-helix domain
EPEFKAOO_01253 3.67e-81 - - - S ko:K07090 - ko00000 membrane transporter protein
EPEFKAOO_01255 5.14e-22 ytgB - - S - - - Transglycosylase associated protein
EPEFKAOO_01256 7.47e-106 - - - K ko:K20375 ko02024,map02024 ko00000,ko00001,ko03000 Transcriptional activator, Rgg GadR MutR family
EPEFKAOO_01257 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
EPEFKAOO_01258 2.34e-301 gntP - - EG ko:K03299 - ko00000,ko02000 Gluconate
EPEFKAOO_01259 3.42e-234 - - - K ko:K02525 - ko00000,ko03000 Transcriptional regulator, LacI family
EPEFKAOO_01260 2.74e-81 - - - - - - - -
EPEFKAOO_01261 2.83e-282 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
EPEFKAOO_01262 1.15e-122 - - - V - - - VanZ like family
EPEFKAOO_01263 9.01e-33 - - - L ko:K14060 - ko00000 recombinase activity
EPEFKAOO_01264 3.79e-118 dpnM 2.1.1.72 - H ko:K06223 ko03430,map03430 ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 Site-specific DNA-methyltransferase (adenine-specific)
EPEFKAOO_01265 8.03e-78 - - - L - - - Restriction endonuclease EcoRV
EPEFKAOO_01266 9.08e-65 - - - L - - - Transposase and inactivated derivatives, IS30 family
EPEFKAOO_01267 3.67e-184 repA - - S - - - Replication initiator protein A
EPEFKAOO_01271 2.46e-228 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EPEFKAOO_01272 1.19e-33 - - - L ko:K07497 - ko00000 hmm pf00665
EPEFKAOO_01273 3.81e-32 - - - L ko:K14060 - ko00000 recombinase activity
EPEFKAOO_01275 0.0 yfiC - - V ko:K06147 - ko00000,ko02000 ABC transporter
EPEFKAOO_01276 0.0 ycfI - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
EPEFKAOO_01277 1.02e-102 - - - K - - - Winged helix-turn-helix DNA-binding
EPEFKAOO_01278 2.33e-10 - - - - - - - -
EPEFKAOO_01280 1.55e-74 - - - - - - - -
EPEFKAOO_01282 3.16e-169 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Belongs to the alpha-acetolactate decarboxylase family
EPEFKAOO_01283 5.46e-186 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
EPEFKAOO_01284 9.18e-206 yvgN - - S - - - Aldo keto reductase
EPEFKAOO_01285 8.6e-157 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
EPEFKAOO_01286 1.74e-111 - - - K - - - GNAT family
EPEFKAOO_01289 1.06e-300 gadB 4.1.1.15, 4.1.2.27 - E ko:K01580,ko:K01634 ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940 ko00000,ko00001,ko00002,ko01000 Belongs to the group II decarboxylase family
EPEFKAOO_01290 4.99e-53 - - - E ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 Amino acid permease
EPEFKAOO_01291 9.84e-99 - - - E ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 Amino acid permease
EPEFKAOO_01292 2.42e-43 axe - - K ko:K21498 - ko00000,ko02048 Helix-turn-helix XRE-family like proteins
EPEFKAOO_01293 5.61e-41 ygbF - - S - - - Sugar efflux transporter for intercellular exchange
EPEFKAOO_01294 8.75e-219 tdh 1.1.1.14 - C ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Zinc-binding dehydrogenase
EPEFKAOO_01295 0.0 guaD 3.5.4.3 - F ko:K01487 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Amidohydrolase family
EPEFKAOO_01296 8.01e-276 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
EPEFKAOO_01298 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
EPEFKAOO_01299 4.92e-99 argR2 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
EPEFKAOO_01300 1.14e-189 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
EPEFKAOO_01301 4.86e-201 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
EPEFKAOO_01302 1.64e-25 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
EPEFKAOO_01303 0.0 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
EPEFKAOO_01304 2e-206 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EPEFKAOO_01305 4.67e-90 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EPEFKAOO_01306 2.1e-94 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
EPEFKAOO_01307 4.01e-261 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
EPEFKAOO_01308 8.74e-62 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
EPEFKAOO_01309 1.2e-70 ysxB - - J ko:K07584 - ko00000 Cysteine protease Prp
EPEFKAOO_01310 1.09e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
EPEFKAOO_01311 3.17e-149 - - - K - - - Transcriptional regulator
EPEFKAOO_01313 1.1e-120 - - - S - - - Protein conserved in bacteria
EPEFKAOO_01314 5.32e-229 - - - - - - - -
EPEFKAOO_01315 8.07e-203 - - - - - - - -
EPEFKAOO_01316 4.76e-19 - - - - - - - -
EPEFKAOO_01317 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
EPEFKAOO_01318 2.56e-220 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EPEFKAOO_01319 3.51e-33 WQ51_02665 - - S - - - Protein of unknown function (DUF3042)
EPEFKAOO_01320 5.91e-93 yqhL - - P - - - Rhodanese-like protein
EPEFKAOO_01321 4.13e-228 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
EPEFKAOO_01322 1.14e-48 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
EPEFKAOO_01323 9.2e-134 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Peptidase, S54 family
EPEFKAOO_01324 3.66e-127 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EPEFKAOO_01325 7.58e-30 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
EPEFKAOO_01326 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
EPEFKAOO_01327 0.0 - - - S - - - membrane
EPEFKAOO_01328 1.81e-103 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
EPEFKAOO_01329 2.93e-151 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
EPEFKAOO_01330 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
EPEFKAOO_01331 4.45e-253 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EPEFKAOO_01332 1.44e-78 yodB - - K - - - Transcriptional regulator, HxlR family
EPEFKAOO_01333 4.08e-117 XK27_09705 - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
EPEFKAOO_01334 4.52e-181 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EPEFKAOO_01335 8.13e-62 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
EPEFKAOO_01336 1.43e-199 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EPEFKAOO_01337 8.81e-89 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
EPEFKAOO_01338 5.4e-298 - - - V - - - MatE
EPEFKAOO_01339 0.0 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EPEFKAOO_01340 1.38e-155 csrR - - K - - - response regulator
EPEFKAOO_01341 7.89e-38 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
EPEFKAOO_01342 2.79e-126 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
EPEFKAOO_01343 1.37e-272 ylbM - - S - - - Belongs to the UPF0348 family
EPEFKAOO_01344 7.76e-182 yqeM - - Q - - - Methyltransferase
EPEFKAOO_01345 4.82e-78 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
EPEFKAOO_01346 5.53e-145 yqeK - - H - - - Hydrolase, HD family
EPEFKAOO_01347 1.62e-120 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EPEFKAOO_01348 1.38e-65 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein
EPEFKAOO_01349 2.2e-273 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
EPEFKAOO_01350 1.69e-125 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
EPEFKAOO_01351 7.57e-33 - - - S - - - Protein of unknown function (DUF1275)
EPEFKAOO_01352 2.58e-24 - - - S - - - Protein of unknown function (DUF1275)
EPEFKAOO_01353 4.67e-75 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EPEFKAOO_01354 1.05e-36 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
EPEFKAOO_01355 6.95e-111 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EPEFKAOO_01356 2.66e-221 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
EPEFKAOO_01357 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 replication initiation and membrane attachment
EPEFKAOO_01358 1.99e-104 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EPEFKAOO_01359 2.4e-136 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EPEFKAOO_01360 7.57e-208 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
EPEFKAOO_01361 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EPEFKAOO_01362 1.14e-178 yfhR3 - - S ko:K06889 - ko00000 Serine hydrolase (FSH1)
EPEFKAOO_01363 1.24e-146 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
EPEFKAOO_01364 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
EPEFKAOO_01365 1.11e-152 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
EPEFKAOO_01366 1.53e-72 ytpP - - CO - - - Thioredoxin
EPEFKAOO_01367 1.68e-76 - - - S - - - Small secreted protein
EPEFKAOO_01368 9.51e-161 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
EPEFKAOO_01369 3.13e-274 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
EPEFKAOO_01370 3.68e-171 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EPEFKAOO_01371 4.29e-101 hit - - FG ko:K02503 - ko00000,ko04147 histidine triad
EPEFKAOO_01373 6.67e-192 prsA 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
EPEFKAOO_01374 4.3e-229 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 Metal dependent phosphohydrolases with conserved 'HD' motif.
EPEFKAOO_01375 3.95e-73 yheA - - S - - - Belongs to the UPF0342 family
EPEFKAOO_01376 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
EPEFKAOO_01377 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
EPEFKAOO_01379 4.86e-53 - - - - - - - -
EPEFKAOO_01381 4.95e-256 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 dihydropteroate synthase
EPEFKAOO_01382 7.57e-135 folQ 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Ham1 family
EPEFKAOO_01383 5.82e-309 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
EPEFKAOO_01384 9.65e-135 folE 2.7.6.3, 3.5.4.16 - F ko:K00950,ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase 1
EPEFKAOO_01385 7.52e-121 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
EPEFKAOO_01386 2.44e-82 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EPEFKAOO_01387 2.89e-152 XK27_07085 - - S ko:K07052 - ko00000 CAAX protease self-immunity
EPEFKAOO_01388 2.6e-234 rbsR - - K ko:K02529 - ko00000,ko03000 Periplasmic binding proteins and sugar binding domain of LacI family
EPEFKAOO_01389 9.92e-143 - - - - - - - -
EPEFKAOO_01390 3.06e-150 dgk2 - - F - - - deoxynucleoside kinase
EPEFKAOO_01391 9.79e-242 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
EPEFKAOO_01392 0.0 - - - S - - - Putative peptidoglycan binding domain
EPEFKAOO_01393 2.01e-113 - - - T - - - Belongs to the universal stress protein A family
EPEFKAOO_01394 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
EPEFKAOO_01395 4.66e-199 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EPEFKAOO_01396 1.92e-80 - - - S - - - Domain of unknown function DUF302
EPEFKAOO_01397 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
EPEFKAOO_01398 9.88e-57 - - - - - - - -
EPEFKAOO_01399 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
EPEFKAOO_01400 1.02e-163 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
EPEFKAOO_01401 4.39e-286 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EPEFKAOO_01402 1.87e-180 proB 2.7.2.11 - F ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EPEFKAOO_01403 3.78e-271 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EPEFKAOO_01404 3.23e-64 - - - - - - - -
EPEFKAOO_01405 2.7e-126 tag1 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
EPEFKAOO_01406 0.0 - - - EGP - - - Major Facilitator
EPEFKAOO_01407 3.59e-111 perR - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
EPEFKAOO_01408 4.5e-314 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
EPEFKAOO_01409 3.91e-31 - - - - - - - -
EPEFKAOO_01412 6.81e-150 - - - K - - - Transcriptional regulator, TetR family
EPEFKAOO_01413 6.84e-103 hsp1 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
EPEFKAOO_01414 5.98e-111 ykhA 3.1.2.20 - I ko:K01073 - ko00000,ko01000 Thioesterase superfamily
EPEFKAOO_01415 1.1e-90 - - - M - - - LysM domain protein
EPEFKAOO_01416 3.23e-251 adh 1.1.1.1 - C ko:K00001,ko:K18369 ko00010,ko00071,ko00350,ko00625,ko00626,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Zinc-binding dehydrogenase
EPEFKAOO_01417 1.85e-301 - - - F ko:K03458 - ko00000 Permease
EPEFKAOO_01418 8.46e-206 - - - O - - - Uncharacterized protein family (UPF0051)
EPEFKAOO_01419 2.56e-145 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EPEFKAOO_01420 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
EPEFKAOO_01421 9.14e-145 arpJ - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
EPEFKAOO_01422 8.27e-184 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
EPEFKAOO_01423 3.99e-06 - - - K - - - Transcriptional regulator
EPEFKAOO_01433 2.82e-252 int2 - - L - - - Belongs to the 'phage' integrase family
EPEFKAOO_01435 1.03e-106 atkY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor CopY TcrY
EPEFKAOO_01436 7.91e-55 - - - - - - - -
EPEFKAOO_01437 1.04e-218 - - - GK - - - ROK family
EPEFKAOO_01438 7.12e-165 - - - C - - - Oxidoreductase NAD-binding domain
EPEFKAOO_01439 0.0 ubiB - - S ko:K03688 - ko00000 ABC1 family
EPEFKAOO_01440 2.68e-134 - - - K - - - Acetyltransferase (GNAT) family
EPEFKAOO_01441 2.51e-90 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EPEFKAOO_01442 4.96e-72 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EPEFKAOO_01443 6.33e-72 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EPEFKAOO_01444 6.87e-117 yejD 2.4.2.6 - F ko:K08728 ko00240,map00240 ko00000,ko00001,ko01000 nucleoside 2-deoxyribosyltransferase
EPEFKAOO_01445 1.08e-22 - - - EGP - - - Major Facilitator
EPEFKAOO_01446 0.0 copA 3.6.3.3, 3.6.3.5, 3.6.3.54 - P ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
EPEFKAOO_01447 1.35e-18 - - - S - - - Cupredoxin-like domain
EPEFKAOO_01448 3.07e-67 - - - S - - - Cupredoxin-like domain
EPEFKAOO_01449 5.81e-226 - - - - - - - -
EPEFKAOO_01450 6.98e-286 araT 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
EPEFKAOO_01451 1.15e-169 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EPEFKAOO_01452 2.29e-220 adhC 1.1.1.90 - C ko:K00055 ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Zn-dependent alcohol dehydrogenases, class III
EPEFKAOO_01453 4.14e-116 citR - - K - - - sugar-binding domain protein
EPEFKAOO_01454 2.34e-166 citG 2.4.2.52 - H ko:K05966 ko02020,map02020 ko00000,ko00001,ko01000 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
EPEFKAOO_01455 1.07e-88 - - - I - - - Alpha/beta hydrolase family
EPEFKAOO_01456 4.23e-136 - - - L - - - Integrase
EPEFKAOO_01457 4.58e-59 - - - K - - - transcriptional regulator
EPEFKAOO_01458 6.05e-141 - - - GM - - - NmrA-like family
EPEFKAOO_01459 2.68e-32 - - - C - - - Flavodoxin
EPEFKAOO_01460 3.31e-165 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
EPEFKAOO_01461 1.33e-192 yitS - - S - - - EDD domain protein, DegV family
EPEFKAOO_01462 1.25e-116 - - - K - - - Domain of unknown function (DUF1836)
EPEFKAOO_01463 2.5e-230 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Peroxidase
EPEFKAOO_01464 2.22e-231 manL 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
EPEFKAOO_01465 2.38e-164 manY - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system
EPEFKAOO_01466 1.37e-219 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
EPEFKAOO_01467 1.8e-76 manO - - S - - - Domain of unknown function (DUF956)
EPEFKAOO_01468 2.85e-220 - - - U ko:K07241 - ko00000,ko02000 High-affinity nickel-transport protein
EPEFKAOO_01469 6.33e-160 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
EPEFKAOO_01470 2.67e-187 larE - - S ko:K06864 - ko00000 NAD synthase
EPEFKAOO_01471 2.19e-289 larC 4.99.1.12 - S ko:K09121 - ko00000,ko01000 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
EPEFKAOO_01472 1.13e-171 larB - - S ko:K06898 - ko00000 AIR carboxylase
EPEFKAOO_01473 5.48e-298 larA 5.1.2.1 - S ko:K22373 ko00620,map00620 ko00000,ko00001,ko01000 Domain of unknown function (DUF2088)
EPEFKAOO_01474 1.01e-157 rcfB - - K - - - Crp-like helix-turn-helix domain
EPEFKAOO_01475 4.46e-129 - - - S ko:K07002 - ko00000 Serine hydrolase
EPEFKAOO_01476 4.35e-79 - - - T ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
EPEFKAOO_01477 8.39e-56 - - - K - - - prlF antitoxin for toxin YhaV_toxin
EPEFKAOO_01478 2.22e-78 - - - S - - - branched-chain amino acid
EPEFKAOO_01479 1.73e-187 - - - E - - - AzlC protein
EPEFKAOO_01480 1.13e-267 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
EPEFKAOO_01481 3.76e-268 hpk31 - - T - - - Histidine kinase
EPEFKAOO_01482 1.06e-158 vanR - - K - - - response regulator
EPEFKAOO_01483 4.56e-120 - - - S ko:K09705 - ko00000 Cupin superfamily (DUF985)
EPEFKAOO_01484 1.61e-105 - - - K - - - Transcriptional regulator
EPEFKAOO_01485 3.12e-100 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
EPEFKAOO_01486 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EPEFKAOO_01487 4.23e-76 - - - - - - - -
EPEFKAOO_01488 1.5e-174 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
EPEFKAOO_01489 1.54e-226 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
EPEFKAOO_01490 4.82e-72 - - - - - - - -
EPEFKAOO_01491 3.4e-83 - - - M - - - Domain of unknown function (DUF4422)
EPEFKAOO_01492 7.32e-76 - - - M - - - Capsular polysaccharide synthesis protein
EPEFKAOO_01493 6.2e-38 - - - M - - - Glycosyltransferase like family 2
EPEFKAOO_01495 1.23e-41 wcaB 2.3.1.30 - E ko:K00640,ko:K03819 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 serine acetyltransferase
EPEFKAOO_01496 4.42e-138 - - - S - - - polysaccharide biosynthetic process
EPEFKAOO_01497 0.00037 - - - S - - - Protein of unknown function (DUF4064)
EPEFKAOO_01500 3.39e-39 - 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 DnaB-like helicase C terminal domain
EPEFKAOO_01501 2.71e-140 - 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 DnaB-like helicase C terminal domain
EPEFKAOO_01502 5.29e-155 butA 1.1.1.304, 1.1.1.76 - IQ ko:K03366 ko00650,map00650 ko00000,ko00001,ko01000 reductase
EPEFKAOO_01503 7.13e-18 - - - S - - - Homeodomain-like domain
EPEFKAOO_01505 1.05e-195 - - - - - - - -
EPEFKAOO_01507 0.0 - - - G - - - Major Facilitator Superfamily
EPEFKAOO_01508 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
EPEFKAOO_01509 1.31e-245 ampC - - V - - - Beta-lactamase
EPEFKAOO_01510 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EPEFKAOO_01511 2.31e-63 - - - - - - - -
EPEFKAOO_01512 7.49e-181 - - - S ko:K07009 - ko00000 CobB/CobQ-like glutamine amidotransferase domain
EPEFKAOO_01513 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Domain of unknown function (DUF1727)
EPEFKAOO_01514 1.78e-139 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
EPEFKAOO_01515 8.85e-207 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EPEFKAOO_01516 1.92e-203 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
EPEFKAOO_01517 2.77e-249 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
EPEFKAOO_01518 9e-294 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EPEFKAOO_01519 3.86e-149 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EPEFKAOO_01520 8.52e-254 yibE - - S - - - overlaps another CDS with the same product name
EPEFKAOO_01521 1.35e-165 yibF - - S - - - overlaps another CDS with the same product name
EPEFKAOO_01522 4.48e-295 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
EPEFKAOO_01523 5.66e-168 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
EPEFKAOO_01524 2.13e-27 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EPEFKAOO_01525 3.92e-80 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EPEFKAOO_01526 1.23e-119 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EPEFKAOO_01527 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EPEFKAOO_01528 1.78e-213 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EPEFKAOO_01529 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EPEFKAOO_01530 2.8e-87 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
EPEFKAOO_01531 8.07e-40 - - - S - - - Protein of unknown function (DUF1146)
EPEFKAOO_01532 2.3e-276 - - - M - - - EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
EPEFKAOO_01533 9.42e-234 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
EPEFKAOO_01534 7.67e-43 - - - S - - - Protein of unknown function (DUF2969)
EPEFKAOO_01535 2.95e-282 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
EPEFKAOO_01537 9.42e-232 - - - S - - - Protein of unknown function (DUF2785)
EPEFKAOO_01538 5.85e-275 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
EPEFKAOO_01539 5.45e-192 - - - K - - - Helix-turn-helix XRE-family like proteins
EPEFKAOO_01540 5e-106 uspA - - T - - - universal stress protein
EPEFKAOO_01542 1.3e-300 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
EPEFKAOO_01543 6.61e-110 XK27_05190 - - S - - - Protein of unknown function (DUF1694)
EPEFKAOO_01544 1.52e-98 - 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase
EPEFKAOO_01545 2.3e-173 - - - S - - - Membrane
EPEFKAOO_01546 6.07e-190 - - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
EPEFKAOO_01547 8.61e-35 - - - S - - - YjcQ protein
EPEFKAOO_01549 5.1e-140 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EPEFKAOO_01550 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EPEFKAOO_01551 8.29e-273 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
EPEFKAOO_01552 2.03e-292 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EPEFKAOO_01553 3.24e-277 yojA - - EG ko:K03299 - ko00000,ko02000 GntP family permease
EPEFKAOO_01554 2.6e-259 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
EPEFKAOO_01557 3.11e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EPEFKAOO_01558 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
EPEFKAOO_01559 9.45e-317 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
EPEFKAOO_01560 5.3e-150 radC - - L ko:K03630 - ko00000 DNA repair protein
EPEFKAOO_01561 1.34e-232 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
EPEFKAOO_01562 1.37e-187 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
EPEFKAOO_01563 9.04e-120 mreD - - M ko:K03571 - ko00000,ko03036 rod shape-determining protein MreD
EPEFKAOO_01564 3.81e-142 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
EPEFKAOO_01565 2.31e-147 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
EPEFKAOO_01566 1.65e-205 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
EPEFKAOO_01567 3.85e-297 ymfF - - S - - - Peptidase M16 inactive domain protein
EPEFKAOO_01568 0.0 ymfH - - S - - - Peptidase M16
EPEFKAOO_01569 1.64e-151 - - - S - - - Helix-turn-helix domain
EPEFKAOO_01570 1.79e-132 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EPEFKAOO_01571 1.62e-293 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
EPEFKAOO_01572 7.88e-245 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EPEFKAOO_01573 6.87e-300 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
EPEFKAOO_01574 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EPEFKAOO_01575 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EPEFKAOO_01576 8.79e-136 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
EPEFKAOO_01577 5.98e-242 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
EPEFKAOO_01578 4.41e-226 - 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 queuine tRNA-ribosyltransferase activity
EPEFKAOO_01579 1.11e-68 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
EPEFKAOO_01580 3.41e-231 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
EPEFKAOO_01581 1.7e-300 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
EPEFKAOO_01582 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EPEFKAOO_01583 1.06e-57 yrzL - - S - - - Belongs to the UPF0297 family
EPEFKAOO_01584 4.97e-97 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EPEFKAOO_01585 3.99e-55 yrzB - - S - - - Belongs to the UPF0473 family
EPEFKAOO_01586 4.55e-211 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EPEFKAOO_01587 2.23e-119 cvpA - - S - - - Colicin V production protein
EPEFKAOO_01588 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
EPEFKAOO_01589 1.66e-71 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
EPEFKAOO_01590 4.19e-283 - - - P - - - Chloride transporter, ClC family
EPEFKAOO_01591 1.96e-120 yslB - - S - - - Protein of unknown function (DUF2507)
EPEFKAOO_01592 1.83e-189 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
EPEFKAOO_01593 2.65e-140 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EPEFKAOO_01594 3.33e-123 - - - S ko:K07095 - ko00000 Phosphoesterase
EPEFKAOO_01595 1.75e-193 - - - S - - - haloacid dehalogenase-like hydrolase
EPEFKAOO_01596 3.7e-201 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
EPEFKAOO_01597 5.99e-67 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
EPEFKAOO_01598 4.62e-92 - - - - - - - -
EPEFKAOO_01599 4.41e-272 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
EPEFKAOO_01600 1.2e-237 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
EPEFKAOO_01601 1.99e-181 - - - - - - - -
EPEFKAOO_01602 5.01e-172 yebC - - K - - - Transcriptional regulatory protein
EPEFKAOO_01603 6.81e-123 - - - M - - - PFAM NLP P60 protein
EPEFKAOO_01604 5.39e-200 ykcB - - M - - - Dolichyl-phosphate-mannose-protein mannosyltransferase
EPEFKAOO_01605 7.24e-200 ykcB - - M - - - Dolichyl-phosphate-mannose-protein mannosyltransferase
EPEFKAOO_01606 2.58e-226 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
EPEFKAOO_01607 7.13e-211 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
EPEFKAOO_01608 8.88e-63 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 competence protein ComGC
EPEFKAOO_01613 6.17e-203 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
EPEFKAOO_01614 9.57e-287 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EPEFKAOO_01615 7.82e-147 - - - S - - - Calcineurin-like phosphoesterase
EPEFKAOO_01616 7.75e-126 yutD - - S - - - Protein of unknown function (DUF1027)
EPEFKAOO_01617 1.01e-182 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
EPEFKAOO_01618 9.59e-22 - - - S - - - Protein of unknown function (DUF1461)
EPEFKAOO_01619 2.38e-141 dedA - - S ko:K03975 - ko00000 SNARE-like domain protein
EPEFKAOO_01620 2.78e-120 - - - L - - - Bacterial dnaA protein
EPEFKAOO_01621 0.0 - - - M - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EPEFKAOO_01622 1.52e-82 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
EPEFKAOO_01623 8.34e-101 - - - - - - - -
EPEFKAOO_01626 2.51e-71 - - - C - - - Zinc-binding dehydrogenase
EPEFKAOO_01627 7.95e-132 - - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, permease protein
EPEFKAOO_01628 3.82e-180 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
EPEFKAOO_01629 3.63e-138 proWZ - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
EPEFKAOO_01630 2.84e-209 proWY - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, QAT family
EPEFKAOO_01631 7.28e-101 ywnA - - K - - - Transcriptional regulator
EPEFKAOO_01632 5.23e-97 - - - O ko:K07397 - ko00000 OsmC-like protein
EPEFKAOO_01633 4.74e-51 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
EPEFKAOO_01634 0.000481 - - - S - - - Protein of unknown function (DUF4064)
EPEFKAOO_01635 5.86e-105 - - - L - - - PFAM transposase, IS4 family protein
EPEFKAOO_01637 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Aluminium induced protein
EPEFKAOO_01639 2.78e-237 - - - EGP - - - Major Facilitator
EPEFKAOO_01640 0.0 dam 2.1.1.72 - L ko:K07318 - ko00000,ko01000,ko02048 D12 class N6 adenine-specific DNA methyltransferase
EPEFKAOO_01641 0.0 - - - L - - - AlwI restriction endonuclease
EPEFKAOO_01642 1.46e-55 - - - - - - - -
EPEFKAOO_01643 0.0 - 3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54 - P ko:K01533,ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 E1-E2 ATPase
EPEFKAOO_01644 1.04e-45 copZ - - P - - - Heavy-metal-associated domain
EPEFKAOO_01645 1.19e-61 - - - D - - - Di-iron-containing protein involved in the repair of iron-sulfur clusters
EPEFKAOO_01646 2.22e-146 - - - K ko:K21562 - ko00000,ko03000 Transcriptional regulator, Crp Fnr family
EPEFKAOO_01647 1.39e-93 crtM 2.5.1.32, 2.5.1.96, 2.5.1.99 - I ko:K02291,ko:K10208 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Squalene/phytoene synthase
EPEFKAOO_01648 3.46e-225 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
EPEFKAOO_01649 1.75e-151 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EPEFKAOO_01650 3.78e-99 pinR1 - - L - - - Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
EPEFKAOO_01651 4.23e-93 - - - L - - - Transposase and inactivated derivatives, IS30 family
EPEFKAOO_01652 2.75e-26 - - - S - - - Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units
EPEFKAOO_01653 6.17e-238 arsB - - P ko:K03325 - ko00000,ko02000 Sodium Bile acid symporter family
EPEFKAOO_01654 1.58e-74 arsR - - K ko:K03892 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
EPEFKAOO_01655 2.37e-239 - - - S - - - interspecies interaction between organisms
EPEFKAOO_01656 2.78e-85 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
EPEFKAOO_01657 5.57e-104 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EPEFKAOO_01658 8.08e-188 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
EPEFKAOO_01659 2.37e-178 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EPEFKAOO_01660 2.06e-201 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EPEFKAOO_01661 1.75e-192 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EPEFKAOO_01662 1.02e-80 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
EPEFKAOO_01663 3.48e-217 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EPEFKAOO_01664 8.02e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EPEFKAOO_01665 1.32e-76 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EPEFKAOO_01666 6.38e-20 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
EPEFKAOO_01667 1.69e-45 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EPEFKAOO_01668 2.16e-156 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
EPEFKAOO_01669 1.36e-301 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
EPEFKAOO_01670 6.05e-93 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
EPEFKAOO_01671 1.2e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
EPEFKAOO_01672 3.59e-113 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EPEFKAOO_01673 5.55e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EPEFKAOO_01674 1.02e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EPEFKAOO_01675 7.64e-88 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EPEFKAOO_01676 2.46e-40 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EPEFKAOO_01677 1.75e-123 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EPEFKAOO_01678 1.28e-65 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EPEFKAOO_01679 2.55e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EPEFKAOO_01680 4.48e-55 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EPEFKAOO_01681 1.35e-38 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
EPEFKAOO_01682 2.78e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EPEFKAOO_01683 3.43e-156 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EPEFKAOO_01684 2.63e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EPEFKAOO_01685 1.51e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EPEFKAOO_01686 3.32e-203 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EPEFKAOO_01687 2.76e-60 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
EPEFKAOO_01688 7.43e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
EPEFKAOO_01689 5.89e-153 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EPEFKAOO_01690 2.58e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
EPEFKAOO_01691 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EPEFKAOO_01692 4.15e-108 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
EPEFKAOO_01693 3.58e-93 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EPEFKAOO_01694 7.05e-40 pilD 3.4.23.43 - NOU ko:K02236,ko:K02506,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 aspartic-type endopeptidase activity
EPEFKAOO_01695 3.02e-275 - - - - - - - -
EPEFKAOO_01696 2.92e-173 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
EPEFKAOO_01697 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EPEFKAOO_01698 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EPEFKAOO_01699 8.51e-137 - - - K - - - Bacterial regulatory proteins, tetR family
EPEFKAOO_01700 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
EPEFKAOO_01701 6.36e-103 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
EPEFKAOO_01702 1.37e-247 adhP 1.1.1.1 - C ko:K00001,ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
EPEFKAOO_01703 1.69e-170 XK27_07210 - - S - - - B3 4 domain
EPEFKAOO_01704 8.62e-154 - - - J - - - 2'-5' RNA ligase superfamily
EPEFKAOO_01706 5.67e-56 - - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
EPEFKAOO_01707 4.13e-190 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
EPEFKAOO_01708 7.16e-58 - - - IQ - - - reductase
EPEFKAOO_01709 5.16e-15 fabG1 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EPEFKAOO_01715 4.69e-151 dgk2 - - F - - - deoxynucleoside kinase
EPEFKAOO_01716 0.0 lysP - - E ko:K03293,ko:K11733 - ko00000,ko02000 amino acid
EPEFKAOO_01718 5.1e-201 - - - I - - - alpha/beta hydrolase fold
EPEFKAOO_01719 2.57e-148 - - - I - - - phosphatase
EPEFKAOO_01720 8.17e-107 - - - S - - - Threonine/Serine exporter, ThrE
EPEFKAOO_01721 5.52e-161 - - - S - - - Putative threonine/serine exporter
EPEFKAOO_01722 1.26e-42 cspC - - K ko:K03704 - ko00000,ko03000 Cold shock protein
EPEFKAOO_01723 2.51e-158 mntR - - K ko:K03709 - ko00000,ko03000 iron dependent repressor
EPEFKAOO_01724 7.54e-210 - - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
EPEFKAOO_01725 9.24e-151 - - - S - - - membrane
EPEFKAOO_01726 2e-143 - - - S - - - VIT family
EPEFKAOO_01727 2.49e-110 - - - T - - - Belongs to the universal stress protein A family
EPEFKAOO_01728 1.18e-28 elaA - - S ko:K02348 - ko00000 acyltransferase COG2153
EPEFKAOO_01729 7.62e-283 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
EPEFKAOO_01730 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EPEFKAOO_01731 5.49e-76 - - - - - - - -
EPEFKAOO_01732 3.98e-96 - - - K - - - MerR HTH family regulatory protein
EPEFKAOO_01733 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
EPEFKAOO_01734 8.18e-151 - - - S - - - Domain of unknown function (DUF4811)
EPEFKAOO_01735 2.97e-148 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
EPEFKAOO_01736 2.46e-216 yjbO 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
EPEFKAOO_01738 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EPEFKAOO_01739 7.04e-139 - 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 DJ-1/PfpI family
EPEFKAOO_01740 1.92e-241 - - - I - - - Alpha beta
EPEFKAOO_01741 4.18e-156 - 3.2.2.27 - L ko:K21929 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Uracil-DNA glycosylase
EPEFKAOO_01742 0.0 - - - S - - - Putative threonine/serine exporter
EPEFKAOO_01743 3.2e-209 mleR2 - - K - - - LysR family transcriptional regulator
EPEFKAOO_01744 7.13e-288 citP - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
EPEFKAOO_01745 9.13e-270 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
EPEFKAOO_01746 3.78e-282 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
EPEFKAOO_01747 3.53e-117 - - - S - - - NADPH-dependent FMN reductase
EPEFKAOO_01748 3.51e-234 XK27_09615 1.5.1.36 - S ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 reductase
EPEFKAOO_01749 8.85e-289 mleS 1.1.1.38, 4.1.1.101 - C ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme
EPEFKAOO_01750 1.58e-98 mleR - - K - - - LysR family
EPEFKAOO_01751 1.74e-24 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
EPEFKAOO_01752 0.0 npr 1.11.1.1 - C ko:K05910 - ko00000,ko01000 NADH oxidase
EPEFKAOO_01753 4.06e-100 - - - L - - - helicase
EPEFKAOO_01754 2.61e-31 - - - - - - - -
EPEFKAOO_01755 1.49e-29 - - - L - - - Integrase
EPEFKAOO_01756 8.51e-32 - - - L - - - Integrase
EPEFKAOO_01757 1.2e-59 - - - D ko:K19159 - ko00000,ko02048 Antitoxin component of a toxin-antitoxin (TA) module
EPEFKAOO_01758 8.12e-53 - - - S - - - integral membrane protein
EPEFKAOO_01759 5.81e-222 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
EPEFKAOO_01761 7.8e-282 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
EPEFKAOO_01764 4.39e-197 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
EPEFKAOO_01765 5.46e-237 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
EPEFKAOO_01767 4.74e-125 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
EPEFKAOO_01768 0.0 FbpA - - K - - - Fibronectin-binding protein
EPEFKAOO_01769 2.33e-204 - - - S - - - EDD domain protein, DegV family
EPEFKAOO_01770 1.39e-129 - - - - - - - -
EPEFKAOO_01771 1.23e-172 yaaA - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
EPEFKAOO_01772 3.04e-154 yagB - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
EPEFKAOO_01773 5.05e-146 ylbE - - GM - - - NAD(P)H-binding
EPEFKAOO_01774 8.44e-128 - - - K - - - Acetyltransferase (GNAT) domain
EPEFKAOO_01775 9.87e-203 thrB 2.7.1.39 - F ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
EPEFKAOO_01776 5.06e-298 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
EPEFKAOO_01777 0.0 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
EPEFKAOO_01778 1.23e-151 azlC - - E - - - azaleucine resistance protein AzlC
EPEFKAOO_01779 7.76e-72 azlD - - E - - - Branched-chain amino acid transport
EPEFKAOO_01780 1.92e-71 yphJ 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 decarboxylase
EPEFKAOO_01781 4.9e-232 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
EPEFKAOO_01782 2.59e-229 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Transketolase, C-terminal domain protein
EPEFKAOO_01783 7.05e-275 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
EPEFKAOO_01784 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
EPEFKAOO_01785 2.03e-249 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
EPEFKAOO_01786 1.18e-272 - - - E - - - GDSL-like Lipase/Acylhydrolase family
EPEFKAOO_01787 1.4e-26 rlrB - - K - - - LysR substrate binding domain protein
EPEFKAOO_01788 1.2e-67 lysR - - K - - - Transcriptional regulator
EPEFKAOO_01789 4.77e-23 rlrB - - K - - - LysR substrate binding domain protein
EPEFKAOO_01790 8.43e-15 - - - EGP ko:K08196 - ko00000,ko02000 Major Facilitator
EPEFKAOO_01791 0.0 yhdP - - S - - - Transporter associated domain
EPEFKAOO_01792 8.53e-270 mdtG2 - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
EPEFKAOO_01793 1.32e-203 - - - EGP ko:K18934 - ko00000,ko02000 Major Facilitator Superfamily
EPEFKAOO_01794 6.23e-214 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
EPEFKAOO_01795 3.52e-57 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EPEFKAOO_01796 9.59e-304 pts13C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EPEFKAOO_01797 2.82e-204 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
EPEFKAOO_01798 0.0 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
EPEFKAOO_01799 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
EPEFKAOO_01800 4.64e-36 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
EPEFKAOO_01801 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EPEFKAOO_01803 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
EPEFKAOO_01804 3.98e-65 - - - - - - - -
EPEFKAOO_01805 7.43e-16 - - - - - - - -
EPEFKAOO_01806 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
EPEFKAOO_01808 9.71e-302 lmrB - - U ko:K18926 - ko00000,ko00002,ko02000 Belongs to the major facilitator superfamily
EPEFKAOO_01809 7.24e-204 - - - S - - - Alpha beta hydrolase
EPEFKAOO_01810 1.57e-118 - - - GM - - - NAD(P)H-binding
EPEFKAOO_01811 2.09e-66 - - - GM - - - NAD(P)H-binding
EPEFKAOO_01812 1.84e-195 supH - - S - - - Sucrose-6F-phosphate phosphohydrolase
EPEFKAOO_01815 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
EPEFKAOO_01817 4.1e-272 - - - G - - - Major Facilitator Superfamily
EPEFKAOO_01818 7.56e-15 aroH 5.4.99.5 - E ko:K04516 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Chorismate mutase
EPEFKAOO_01819 2.83e-188 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EPEFKAOO_01820 5.2e-69 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EPEFKAOO_01821 1.9e-132 - - - - - - - -
EPEFKAOO_01822 9.54e-302 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
EPEFKAOO_01823 1.95e-249 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
EPEFKAOO_01824 2.61e-117 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EPEFKAOO_01825 2.6e-278 aspB3 - - E - - - DegT/DnrJ/EryC1/StrS aminotransferase family
EPEFKAOO_01826 6.92e-235 - 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EPEFKAOO_01827 3.65e-226 hepT 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
EPEFKAOO_01828 2.22e-201 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
EPEFKAOO_01829 1.25e-31 - - - S - - - Virus attachment protein p12 family
EPEFKAOO_01830 0.0 feoB - - P ko:K04759 - ko00000,ko02000 transporter of a GTP-driven Fe(2 ) uptake system
EPEFKAOO_01831 2e-45 feoA - - P ko:K04758 - ko00000,ko02000 FeoA domain
EPEFKAOO_01832 2.3e-186 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
EPEFKAOO_01833 7.7e-312 sufD - - O ko:K07033,ko:K09015 - ko00000 FeS assembly protein SufD
EPEFKAOO_01834 1.06e-297 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EPEFKAOO_01835 2.14e-110 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
EPEFKAOO_01836 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
EPEFKAOO_01837 6e-245 fecB - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
EPEFKAOO_01838 8.87e-245 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
EPEFKAOO_01839 2.6e-75 - - - L - - - Helix-turn-helix domain
EPEFKAOO_01840 2.9e-47 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
EPEFKAOO_01841 7.11e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EPEFKAOO_01842 6.22e-243 - - - L ko:K07482 - ko00000 Helix-turn-helix domain
EPEFKAOO_01849 1.03e-105 - - - L ko:K07491 - ko00000 Transposase IS200 like
EPEFKAOO_01850 4.36e-67 ybjQ - - S - - - Belongs to the UPF0145 family
EPEFKAOO_01851 1.93e-99 - 2.2.1.7 - HI ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 1-deoxy-D-xylulose-5-phosphate synthase
EPEFKAOO_01852 6.82e-34 - 2.2.1.7 - HI ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 1-deoxy-D-xylulose-5-phosphate synthase
EPEFKAOO_01853 4.73e-124 - - - K - - - Bacterial regulatory proteins, tetR family
EPEFKAOO_01854 0.0 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EPEFKAOO_01855 4.8e-38 - - - S - - - FMN_bind
EPEFKAOO_01857 2.89e-43 - - - M - - - Rib/alpha-like repeat
EPEFKAOO_01858 1.12e-293 ylbB - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
EPEFKAOO_01859 3.48e-124 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EPEFKAOO_01860 1.32e-132 - - - K - - - Transcriptional regulator
EPEFKAOO_01861 0.0 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EPEFKAOO_01862 1.18e-303 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
EPEFKAOO_01863 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
EPEFKAOO_01864 2.74e-68 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
EPEFKAOO_01865 1.25e-200 yneP - - L ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
EPEFKAOO_01866 2.38e-14 - - - S - - - NADPH-dependent FMN reductase
EPEFKAOO_01867 3.2e-78 - - - S - - - NADPH-dependent FMN reductase
EPEFKAOO_01868 0.0 ctrA - - E ko:K03294 - ko00000 amino acid
EPEFKAOO_01869 0.0 gabT 2.6.1.19, 5.1.1.21 - E ko:K00823,ko:K20708 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EPEFKAOO_01871 2.35e-196 - - - S ko:K07088 - ko00000 Membrane transport protein
EPEFKAOO_01872 5.57e-70 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
EPEFKAOO_01873 0.0 - 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 pyridine nucleotide-disulfide oxidoreductase
EPEFKAOO_01874 1.03e-265 - - - EGP - - - Major Facilitator
EPEFKAOO_01875 2.35e-269 ycsG - - P - - - Natural resistance-associated macrophage protein
EPEFKAOO_01876 4.23e-165 - - - S ko:K07160 - ko00000 LamB/YcsF family
EPEFKAOO_01877 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
EPEFKAOO_01878 1.12e-86 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
EPEFKAOO_01879 8.19e-244 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
EPEFKAOO_01880 2.19e-172 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
EPEFKAOO_01881 2.31e-95 - - - K - - - helix_turn_helix, mercury resistance
EPEFKAOO_01882 4.35e-108 - - - S - - - Psort location Cytoplasmic, score
EPEFKAOO_01883 0.0 umuC - - L ko:K03502 - ko00000,ko03400 impB/mucB/samB family C-terminal domain
EPEFKAOO_01884 1.7e-122 - - - K - - - Acetyltransferase (GNAT) family
EPEFKAOO_01885 6.2e-135 - - - NU - - - mannosyl-glycoprotein
EPEFKAOO_01886 5.59e-250 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
EPEFKAOO_01887 4.48e-38 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
EPEFKAOO_01888 4.27e-274 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
EPEFKAOO_01889 1.62e-115 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
EPEFKAOO_01890 8.11e-52 - - - S - - - Cytochrome B5
EPEFKAOO_01895 2.57e-309 ycnB - - U - - - Belongs to the major facilitator superfamily
EPEFKAOO_01896 2.21e-122 - - - K - - - transcriptional regulator
EPEFKAOO_01897 9.47e-94 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
EPEFKAOO_01898 0.0 - - - L - - - Helicase C-terminal domain protein
EPEFKAOO_01899 4.42e-71 - - - S - - - MazG-like family
EPEFKAOO_01900 2.18e-138 - - - I - - - PAP2 superfamily
EPEFKAOO_01901 7.09e-252 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
EPEFKAOO_01902 1.28e-126 - - - - - - - -
EPEFKAOO_01903 1.47e-286 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
EPEFKAOO_01904 3.77e-217 - - - V - - - Beta-lactamase enzyme family
EPEFKAOO_01905 0.0 potE - - E - - - Amino Acid
EPEFKAOO_01907 5.32e-142 - - - - - - - -
EPEFKAOO_01908 2.72e-212 - - - S - - - Polyphosphate nucleotide phosphotransferase, PPK2 family
EPEFKAOO_01909 8.5e-212 - - - K - - - LysR substrate binding domain
EPEFKAOO_01910 8.19e-78 - - - GM - - - NmrA-like family
EPEFKAOO_01911 0.0 - - - S ko:K13730 ko05100,map05100 ko00000,ko00001 Uncharacterized protein conserved in bacteria (DUF2252)
EPEFKAOO_01912 0.0 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
EPEFKAOO_01913 7.06e-251 adh 1.1.1.1 - C ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Zinc-binding alcohol dehydrogenase family protein
EPEFKAOO_01914 0.0 scrA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EPEFKAOO_01915 1.87e-139 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EPEFKAOO_01916 6.29e-11 - - - S - - - Rib/alpha-like repeat
EPEFKAOO_01918 8.44e-20 - 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 3-hydroxyacyl-CoA dehydrogenase
EPEFKAOO_01920 4.88e-236 fruR3 - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional regulator, LacI family
EPEFKAOO_01921 9.97e-103 - - - F - - - Nucleoside 2-deoxyribosyltransferase
EPEFKAOO_01922 5.27e-125 - - - - - - - -
EPEFKAOO_01924 4.14e-111 int3 - - L - - - Belongs to the 'phage' integrase family
EPEFKAOO_01926 2.92e-07 - - - S - - - sequence-specific DNA binding
EPEFKAOO_01940 5.73e-19 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
EPEFKAOO_01947 1.46e-91 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
EPEFKAOO_01950 2.81e-43 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
EPEFKAOO_01951 6.92e-33 - - - L - - - the current gene model (or a revised gene model) may contain a frame shift
EPEFKAOO_01953 1.58e-189 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative DNA-binding domain
EPEFKAOO_01955 8.44e-57 - - - - - - - -
EPEFKAOO_01961 3.21e-20 - - - D - - - nuclear chromosome segregation
EPEFKAOO_01962 2.48e-50 XK27_00515 - - D - - - Glucan-binding protein C
EPEFKAOO_01966 8.28e-292 - - - L - - - MULE transposase domain
EPEFKAOO_01967 7.5e-57 - - - S - - - integral membrane protein
EPEFKAOO_01969 1.45e-38 - - - I - - - Carboxylesterase family
EPEFKAOO_01970 2.65e-41 - - - I - - - Hydrolase, alpha beta domain protein
EPEFKAOO_01973 2.93e-47 cas2 - - L ko:K09951 - ko00000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EPEFKAOO_01974 1.31e-117 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EPEFKAOO_01975 0.0 cas9 - - L ko:K09952 - ko00000,ko01000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
EPEFKAOO_01976 0.0 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EPEFKAOO_01977 1.18e-178 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EPEFKAOO_01978 5.43e-185 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
EPEFKAOO_01979 2.14e-147 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
EPEFKAOO_01980 2.77e-191 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
EPEFKAOO_01981 2.94e-89 psiE - - S ko:K13256 - ko00000 Phosphate-starvation-inducible E
EPEFKAOO_01982 9.63e-51 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
EPEFKAOO_01983 4.53e-127 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EPEFKAOO_01984 3.44e-201 - - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
EPEFKAOO_01985 4.16e-135 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EPEFKAOO_01986 1.55e-151 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
EPEFKAOO_01987 3.82e-133 cadD - - P - - - Cadmium resistance transporter

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)