ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
NHMLFFNE_00001 1.62e-53 - - - S - - - peptidoglycan binding
NHMLFFNE_00002 2.33e-10 - - - M - - - Cysteine-rich secretory protein family
NHMLFFNE_00003 1.08e-22 - - - M - - - Rib/alpha-like repeat
NHMLFFNE_00004 2.01e-72 - - - - - - - -
NHMLFFNE_00005 2.7e-163 - - - L - - - Transposase
NHMLFFNE_00006 2.18e-143 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
NHMLFFNE_00007 1.27e-55 - - - S - - - Domain of unknown function (DUF4343)
NHMLFFNE_00008 2.66e-16 - - - S - - - Domain of unknown function (DUF4343)
NHMLFFNE_00010 2.67e-54 - - - L ko:K07483 - ko00000 Transposase
NHMLFFNE_00011 1.15e-200 - - - L ko:K07497 - ko00000 Integrase core domain
NHMLFFNE_00012 9.43e-38 - - - K - - - Putative DNA-binding domain
NHMLFFNE_00013 5.96e-77 - - - S - - - Bacteriophage abortive infection AbiH
NHMLFFNE_00016 8.71e-135 - 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 Belongs to the N(4) N(6)-methyltransferase family
NHMLFFNE_00017 5.45e-110 - - - L ko:K03497 - ko00000,ko03000,ko03036,ko04812 N-4 methylation of cytosine
NHMLFFNE_00018 8.82e-152 - - - F - - - helicase superfamily c-terminal domain
NHMLFFNE_00020 9.43e-94 - - - K - - - DNA-templated transcription, initiation
NHMLFFNE_00021 5.78e-35 - - - - - - - -
NHMLFFNE_00022 2.17e-54 - - - - - - - -
NHMLFFNE_00023 4.42e-271 - - - L - - - Protein of unknown function (DUF2800)
NHMLFFNE_00024 6.84e-127 - - - S - - - Protein of unknown function (DUF2815)
NHMLFFNE_00025 0.0 - 2.7.7.7 - L ko:K02334 - ko00000,ko01000 DNA polymerase
NHMLFFNE_00026 3.05e-91 - - - S - - - Psort location Cytoplasmic, score
NHMLFFNE_00027 2.33e-41 - - - S ko:K06919 - ko00000 Phage plasmid primase, P4
NHMLFFNE_00028 0.0 - - - S ko:K06919 - ko00000 Phage plasmid primase, P4
NHMLFFNE_00029 3.57e-61 - - - S - - - VRR_NUC
NHMLFFNE_00030 0.0 - - - L - - - SNF2 family N-terminal domain
NHMLFFNE_00031 1.45e-112 - - - - - - - -
NHMLFFNE_00032 3.28e-128 - - - - - - - -
NHMLFFNE_00033 4.29e-295 - - - KL - - - DNA methylase
NHMLFFNE_00034 2.95e-146 - - - S - - - Psort location Cytoplasmic, score
NHMLFFNE_00035 4e-40 - - - S - - - Domain of unknown function (DUF5049)
NHMLFFNE_00036 0.0 - - - S - - - overlaps another CDS with the same product name
NHMLFFNE_00037 1.17e-310 - - - S - - - Phage portal protein
NHMLFFNE_00038 9.69e-149 - 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S14 family
NHMLFFNE_00039 2.63e-265 - - - S - - - Phage capsid family
NHMLFFNE_00040 2.17e-57 - - - S - - - Phage gp6-like head-tail connector protein
NHMLFFNE_00041 8.73e-87 - - - S - - - Phage head-tail joining protein
NHMLFFNE_00042 9.12e-87 - - - S - - - Bacteriophage holin family
NHMLFFNE_00043 1.35e-171 - - - M - - - Glycosyl hydrolases family 25
NHMLFFNE_00044 3.95e-31 - - - - - - - -
NHMLFFNE_00045 0.0 - - - L - - - Recombinase zinc beta ribbon domain
NHMLFFNE_00046 0.0 - - - L - - - Recombinase
NHMLFFNE_00049 1.57e-101 - - - Q - - - Methyltransferase domain
NHMLFFNE_00050 2.56e-66 - - - K - - - Psort location Cytoplasmic, score
NHMLFFNE_00051 1.17e-74 yjdF3 - - S - - - Protein of unknown function (DUF2992)
NHMLFFNE_00052 0.0 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NHMLFFNE_00053 7.73e-139 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NHMLFFNE_00054 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NHMLFFNE_00055 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NHMLFFNE_00056 8.96e-223 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
NHMLFFNE_00057 1.22e-73 - - - - - - - -
NHMLFFNE_00058 1.42e-87 gtcA - - S - - - Teichoic acid glycosylation protein
NHMLFFNE_00059 4.7e-103 ykuP - - C ko:K03839 - ko00000 Flavodoxin
NHMLFFNE_00060 4.96e-216 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
NHMLFFNE_00061 1.4e-312 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
NHMLFFNE_00062 1.43e-291 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
NHMLFFNE_00063 2.43e-247 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NHMLFFNE_00064 1.99e-152 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NHMLFFNE_00065 0.0 cydC - - CO ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
NHMLFFNE_00066 1.16e-182 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase subunit II
NHMLFFNE_00067 1.27e-290 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
NHMLFFNE_00068 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NHMLFFNE_00069 1.67e-291 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NHMLFFNE_00070 3.52e-274 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
NHMLFFNE_00071 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NHMLFFNE_00072 1.71e-138 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NHMLFFNE_00073 0.0 tdc 4.1.1.25 - E ko:K22330 ko00350,map00350 ko00000,ko00001,ko01000 Pyridoxal-dependent decarboxylase conserved domain
NHMLFFNE_00074 2.08e-260 - - - E ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 Amino acid permease
NHMLFFNE_00075 1.35e-240 ldhA 1.1.1.28 - C ko:K03778,ko:K18347 ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01504 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NHMLFFNE_00076 1.96e-114 - - - S ko:K16927 - ko00000,ko00002,ko02000 ECF transporter, substrate-specific component
NHMLFFNE_00077 1.4e-78 - - - S - - - Domain of unknown function (DUF4430)
NHMLFFNE_00079 8.95e-95 - - - K ko:K18909 - ko00000,ko00002,ko01504,ko03000 helix_turn_helix multiple antibiotic resistance protein
NHMLFFNE_00080 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
NHMLFFNE_00082 8.48e-42 - - - S - - - Terminase-like family
NHMLFFNE_00083 2.68e-72 - - - L ko:K07474 - ko00000 Terminase small subunit
NHMLFFNE_00084 3.41e-80 - - - S - - - HicB_like antitoxin of bacterial toxin-antitoxin system
NHMLFFNE_00085 0.0 - - - I - - - Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NHMLFFNE_00088 2.56e-51 - - - S - - - ORF6C domain
NHMLFFNE_00090 1.08e-20 - - - - - - - -
NHMLFFNE_00093 7.87e-47 - - - T - - - PemK-like, MazF-like toxin of type II toxin-antitoxin system
NHMLFFNE_00094 5.75e-07 - - - T - - - SpoVT / AbrB like domain
NHMLFFNE_00095 7.45e-191 - - - M - - - Glycosyl hydrolases family 25
NHMLFFNE_00096 1.58e-37 - - - S - - - Bacteriophage holin of superfamily 6 (Holin_LLH)
NHMLFFNE_00097 8.21e-216 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
NHMLFFNE_00098 1.77e-210 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
NHMLFFNE_00101 2.27e-220 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
NHMLFFNE_00103 7.92e-76 - - - - - - - -
NHMLFFNE_00104 3.82e-228 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
NHMLFFNE_00105 5.57e-164 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NHMLFFNE_00106 9.69e-72 - - - - - - - -
NHMLFFNE_00107 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NHMLFFNE_00108 1.48e-98 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NHMLFFNE_00109 9.78e-130 - - - S ko:K07002 - ko00000 Serine hydrolase
NHMLFFNE_00111 1.12e-79 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NHMLFFNE_00112 3.74e-136 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NHMLFFNE_00113 7.51e-125 cadA - - P - - - P-type ATPase
NHMLFFNE_00114 7.59e-161 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
NHMLFFNE_00115 1.75e-161 - - - - - - - -
NHMLFFNE_00116 4.47e-16 - - - S - - - Protein of unknown function (DUF4044)
NHMLFFNE_00117 2.81e-76 - - - - - - - -
NHMLFFNE_00118 2.49e-100 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
NHMLFFNE_00119 1.88e-223 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NHMLFFNE_00120 5.75e-72 ftsL - - D - - - Cell division protein FtsL
NHMLFFNE_00121 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
NHMLFFNE_00122 2.48e-226 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NHMLFFNE_00123 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NHMLFFNE_00124 3.42e-259 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NHMLFFNE_00125 3.66e-193 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NHMLFFNE_00126 0.0 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NHMLFFNE_00127 3.77e-288 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NHMLFFNE_00128 1.29e-91 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NHMLFFNE_00129 3.2e-54 ylmG - - S ko:K02221 - ko00000,ko02044 YGGT family
NHMLFFNE_00130 7.48e-190 ylmH - - S - - - S4 domain protein
NHMLFFNE_00131 8.67e-108 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
NHMLFFNE_00132 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NHMLFFNE_00133 4.69e-43 cspB - - K ko:K03704 - ko00000,ko03000 Cold shock protein
NHMLFFNE_00134 2.48e-129 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
NHMLFFNE_00135 1.54e-33 - - - - - - - -
NHMLFFNE_00136 9.36e-160 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NHMLFFNE_00137 9.43e-280 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
NHMLFFNE_00138 3.23e-75 XK27_04120 - - S - - - Putative amino acid metabolism
NHMLFFNE_00139 2.51e-285 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NHMLFFNE_00140 3.3e-158 pgm6 - - G - - - phosphoglycerate mutase
NHMLFFNE_00141 7.71e-157 - - - S - - - repeat protein
NHMLFFNE_00142 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NHMLFFNE_00143 8.58e-223 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NHMLFFNE_00144 2.53e-07 - - - M - - - LPXTG-motif cell wall anchor domain protein
NHMLFFNE_00145 6.88e-214 - - - M - - - LPXTG-motif cell wall anchor domain protein
NHMLFFNE_00146 1.34e-06 - - - M - - - YSIRK type signal peptide
NHMLFFNE_00147 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
NHMLFFNE_00148 1.56e-20 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NHMLFFNE_00149 7.69e-180 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NHMLFFNE_00150 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
NHMLFFNE_00151 1.72e-315 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NHMLFFNE_00152 1.03e-108 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NHMLFFNE_00153 5.75e-136 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NHMLFFNE_00154 4.46e-132 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NHMLFFNE_00155 7.66e-222 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NHMLFFNE_00156 6.08e-179 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NHMLFFNE_00157 4.16e-279 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
NHMLFFNE_00158 6.08e-253 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NHMLFFNE_00161 1.5e-43 - - - - - - - -
NHMLFFNE_00162 4.33e-54 - - - S - - - Bacteriophage holin of superfamily 6 (Holin_LLH)
NHMLFFNE_00163 3.36e-221 - - - M - - - Glycosyl hydrolases family 25
NHMLFFNE_00164 2.94e-14 - - - T - - - SpoVT / AbrB like domain
NHMLFFNE_00165 7.28e-31 - - - T ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
NHMLFFNE_00166 3.85e-47 XK27_07210 - - S - - - B3 4 domain
NHMLFFNE_00167 8.3e-117 - - - - - - - -
NHMLFFNE_00168 5.28e-159 pnb - - C - - - nitroreductase
NHMLFFNE_00169 8.41e-97 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Methyltransferase
NHMLFFNE_00170 3.11e-76 XK27_00915 - - C - - - Luciferase-like monooxygenase
NHMLFFNE_00171 3.24e-51 XK27_00915 - - C - - - Luciferase-like monooxygenase
NHMLFFNE_00172 2e-18 XK27_00915 - - C - - - Luciferase-like monooxygenase
NHMLFFNE_00173 4.07e-217 - 3.2.1.96, 3.5.1.28 GH73 M ko:K01227,ko:K01447,ko:K13714,ko:K13731 ko00511,ko05100,map00511,map05100 ko00000,ko00001,ko01000 N-acetylmuramoyl-L-alanine amidase
NHMLFFNE_00174 8.85e-97 - - - S - - - Protein of unknown function (DUF3021)
NHMLFFNE_00175 5.83e-100 - - - K - - - LytTr DNA-binding domain
NHMLFFNE_00176 8.46e-119 - - - K - - - Acetyltransferase (GNAT) family
NHMLFFNE_00178 6.48e-153 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
NHMLFFNE_00179 3.07e-103 yjcF 3.5.4.33, 4.4.1.8 - K ko:K02348,ko:K07000,ko:K11991,ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007,ko03016 protein acetylation
NHMLFFNE_00180 4.75e-249 - - - S - - - Protein of unknown function (DUF3114)
NHMLFFNE_00181 0.0 gshA 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
NHMLFFNE_00182 7.24e-211 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
NHMLFFNE_00183 1.4e-133 - 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
NHMLFFNE_00184 4.62e-81 - - - S - - - Domain of unknown function (DUF4828)
NHMLFFNE_00185 5.34e-245 mocA - - S - - - Oxidoreductase
NHMLFFNE_00186 2.59e-295 yfmL - - L - - - DEAD DEAH box helicase
NHMLFFNE_00188 3.46e-265 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NHMLFFNE_00189 6.11e-89 recT - - L ko:K07455 - ko00000,ko03400 RecT family
NHMLFFNE_00190 8.08e-77 pi112 - - L - - - PDDEXK-like domain of unknown function (DUF3799)
NHMLFFNE_00191 2.22e-38 - - - - - - - -
NHMLFFNE_00192 3.34e-78 - - - - - - - -
NHMLFFNE_00193 1.1e-142 - - - - - - - -
NHMLFFNE_00194 9.53e-108 - - - S - - - Phage tail assembly chaperone protein, TAC
NHMLFFNE_00196 3.19e-32 - - - D - - - domain protein
NHMLFFNE_00197 7.95e-171 - - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
NHMLFFNE_00198 1.39e-129 - - - S - - - Protein of unknown function (DUF1700)
NHMLFFNE_00199 2.79e-75 XK27_06915 - - K ko:K10947 - ko00000,ko03000 transcriptional regulator PadR family
NHMLFFNE_00200 1.2e-64 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NHMLFFNE_00201 5.83e-308 glpT - - G ko:K02445 - ko00000,ko02000 Major Facilitator Superfamily
NHMLFFNE_00202 4.72e-134 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NHMLFFNE_00204 5.28e-76 - - - - - - - -
NHMLFFNE_00205 4.18e-262 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
NHMLFFNE_00206 6.74e-48 - - - - - - - -
NHMLFFNE_00207 6.7e-35 - - - - - - - -
NHMLFFNE_00209 2.34e-25 - - - K - - - Cro/C1-type HTH DNA-binding domain
NHMLFFNE_00210 9.88e-206 - - - S - - - Polyphosphate nucleotide phosphotransferase, PPK2 family
NHMLFFNE_00211 9.43e-73 - - - - - - - -
NHMLFFNE_00212 7.59e-269 yttB - - EGP - - - Major Facilitator
NHMLFFNE_00213 1.49e-307 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
NHMLFFNE_00214 1.25e-97 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
NHMLFFNE_00215 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
NHMLFFNE_00216 7.87e-150 maa3 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
NHMLFFNE_00217 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
NHMLFFNE_00218 8.12e-32 - - - V - - - Type I restriction
NHMLFFNE_00219 4.42e-86 - - - L - - - Belongs to the 'phage' integrase family
NHMLFFNE_00220 1.1e-119 - - - L - - - Belongs to the 'phage' integrase family
NHMLFFNE_00221 6.24e-46 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 type I restriction modification DNA specificity domain
NHMLFFNE_00222 2.41e-84 - - - K - - - Transcriptional regulator, GntR family
NHMLFFNE_00223 8.64e-143 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NHMLFFNE_00224 9.44e-34 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NHMLFFNE_00225 1.07e-143 - - - - - - - -
NHMLFFNE_00227 0.0 xylT - - EGP - - - Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NHMLFFNE_00228 2.49e-22 nhaP3 - - P ko:K03316 - ko00000 Sodium proton antiporter
NHMLFFNE_00229 1.28e-75 - - - - - - - -
NHMLFFNE_00231 8.03e-116 - - - - - - - -
NHMLFFNE_00232 0.0 copA 3.6.3.3, 3.6.3.5, 3.6.3.54 - P ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
NHMLFFNE_00233 2.2e-65 - - - S - - - Cupredoxin-like domain
NHMLFFNE_00234 6.51e-82 - - - S - - - Cupredoxin-like domain
NHMLFFNE_00235 1.66e-132 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
NHMLFFNE_00236 5.49e-207 - - - EG - - - EamA-like transporter family
NHMLFFNE_00237 3.24e-220 arcC 2.7.2.2 - E ko:K00926 ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200 ko00000,ko00001,ko01000 Belongs to the carbamate kinase family
NHMLFFNE_00238 9.21e-244 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NHMLFFNE_00239 3.71e-199 - - - KT ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 YcbB domain
NHMLFFNE_00240 0.0 - 3.2.1.21, 3.2.1.52 GH3 G ko:K01207,ko:K05349 ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501 ko00000,ko00001,ko00002,ko01000 hydrolase, family 3
NHMLFFNE_00241 0.0 xylB 2.7.1.17, 2.7.1.53 - G ko:K00854,ko:K00880 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the FGGY kinase family
NHMLFFNE_00242 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
NHMLFFNE_00243 7.4e-115 yjeA 3.5.1.104 - G ko:K22278 - ko00000,ko01000 polysaccharide deacetylase
NHMLFFNE_00244 0.0 - - - G - - - Right handed beta helix region
NHMLFFNE_00245 9.8e-306 - - - G ko:K03292 - ko00000 MFS/sugar transport protein
NHMLFFNE_00246 1.8e-150 rhaS2 - - K - - - Transcriptional regulator, AraC family
NHMLFFNE_00247 4.92e-56 rhaS2 - - K - - - Transcriptional regulator, AraC family
NHMLFFNE_00248 9.17e-129 ywlG - - S - - - Belongs to the UPF0340 family
NHMLFFNE_00249 1.89e-123 gshAB 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
NHMLFFNE_00250 7.72e-178 - - - IQ - - - KR domain
NHMLFFNE_00251 3.85e-233 iunH1 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 nucleoside hydrolase
NHMLFFNE_00252 5.66e-73 - - - L ko:K07482 - ko00000 Helix-turn-helix domain
NHMLFFNE_00253 5.01e-101 - - - L ko:K07482 - ko00000 Helix-turn-helix domain
NHMLFFNE_00254 1.05e-45 - - - - - - - -
NHMLFFNE_00258 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
NHMLFFNE_00259 3.49e-30 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
NHMLFFNE_00260 1.3e-264 hpk31 - - T - - - Histidine kinase
NHMLFFNE_00261 9.76e-161 vanR - - K - - - response regulator
NHMLFFNE_00262 1.21e-264 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NHMLFFNE_00263 1.32e-219 deoR - - K ko:K05346 - ko00000,ko03000 sugar-binding domain protein
NHMLFFNE_00264 3.27e-167 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
NHMLFFNE_00265 3.88e-301 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 pyrimidine-nucleoside phosphorylase
NHMLFFNE_00266 1.33e-297 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
NHMLFFNE_00267 2.29e-152 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NHMLFFNE_00268 8.95e-175 - - - S - - - Protein of unknown function (DUF1129)
NHMLFFNE_00269 2.48e-254 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NHMLFFNE_00270 5.8e-43 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
NHMLFFNE_00271 1.32e-195 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
NHMLFFNE_00272 6.57e-177 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
NHMLFFNE_00273 1.69e-196 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
NHMLFFNE_00274 1.13e-165 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
NHMLFFNE_00275 4.2e-208 - 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 3-hydroxyacyl-CoA dehydrogenase
NHMLFFNE_00276 4.78e-218 rihA 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
NHMLFFNE_00277 3.98e-277 nupG - - F ko:K03317,ko:K11535,ko:K16323 - ko00000,ko02000 Nucleoside transporter
NHMLFFNE_00278 1.52e-286 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
NHMLFFNE_00279 6.62e-177 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NHMLFFNE_00280 0.0 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NHMLFFNE_00281 0.0 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NHMLFFNE_00282 1.59e-99 - - - L - - - DNA methylase
NHMLFFNE_00283 1.76e-130 - - - M - - - domain protein
NHMLFFNE_00284 3.97e-134 - - - - - - - -
NHMLFFNE_00285 1.39e-115 - - - S ko:K06926 - ko00000 AAA domain, putative AbiEii toxin, Type IV TA system
NHMLFFNE_00298 2.37e-123 - - - K - - - Acetyltransferase (GNAT) domain
NHMLFFNE_00299 5.07e-39 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
NHMLFFNE_00300 1.01e-129 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
NHMLFFNE_00301 6.27e-270 ylbM - - S - - - Belongs to the UPF0348 family
NHMLFFNE_00302 5.25e-178 yqeM - - Q - - - Methyltransferase
NHMLFFNE_00303 1.53e-78 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NHMLFFNE_00304 8.48e-145 yqeK - - H - - - Hydrolase, HD family
NHMLFFNE_00305 6.96e-158 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NHMLFFNE_00306 8.97e-62 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein
NHMLFFNE_00307 1.74e-275 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
NHMLFFNE_00308 7.78e-125 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
NHMLFFNE_00309 5.46e-74 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NHMLFFNE_00310 1.82e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
NHMLFFNE_00311 2.15e-110 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NHMLFFNE_00312 3.36e-219 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
NHMLFFNE_00313 7.16e-298 dnaB - - L ko:K03346 - ko00000,ko03032 replication initiation and membrane attachment
NHMLFFNE_00314 2.82e-105 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NHMLFFNE_00315 6.16e-131 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NHMLFFNE_00316 2.74e-204 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NHMLFFNE_00317 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NHMLFFNE_00318 1.14e-150 - - - S - - - Protein of unknown function (DUF1275)
NHMLFFNE_00319 4.56e-154 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
NHMLFFNE_00320 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
NHMLFFNE_00321 1.34e-151 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NHMLFFNE_00322 2.95e-75 ytpP - - CO - - - Thioredoxin
NHMLFFNE_00323 0.0 - - - S - - - C4-dicarboxylate anaerobic carrier
NHMLFFNE_00324 1.66e-107 - - - S - - - Double zinc ribbon
NHMLFFNE_00325 2.21e-229 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
NHMLFFNE_00327 2.3e-21 - - - S - - - Hypothetical protein (DUF2513)
NHMLFFNE_00329 1.33e-44 - - - S - - - Hypothetical protein (DUF2513)
NHMLFFNE_00333 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NHMLFFNE_00334 3.82e-77 - - - - - - - -
NHMLFFNE_00335 0.0 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
NHMLFFNE_00336 3.33e-242 - - - E - - - Zinc-binding dehydrogenase
NHMLFFNE_00337 1.25e-124 - - - K - - - PFAM GCN5-related N-acetyltransferase
NHMLFFNE_00338 2.55e-216 - - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
NHMLFFNE_00343 8.22e-49 - - - M - - - Glycosyltransferase like family 2
NHMLFFNE_00344 3.64e-32 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
NHMLFFNE_00345 3.86e-160 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
NHMLFFNE_00346 1.6e-95 - - - - - - - -
NHMLFFNE_00352 5.26e-148 dgk2 - - F - - - deoxynucleoside kinase
NHMLFFNE_00353 6.1e-276 xylR - - GK - - - ROK family
NHMLFFNE_00354 1.19e-37 - - - - - - - -
NHMLFFNE_00355 0.0 yclK - - T - - - Histidine kinase
NHMLFFNE_00356 1.9e-172 yclJ - - K ko:K02483 - ko00000,ko02022 response regulator
NHMLFFNE_00358 2.2e-110 lytE - - M - - - Lysin motif
NHMLFFNE_00359 8.09e-193 - - - S - - - Cof-like hydrolase
NHMLFFNE_00360 3.7e-106 - - - K - - - Transcriptional regulator
NHMLFFNE_00361 0.0 oatA - - I - - - Acyltransferase
NHMLFFNE_00362 5.17e-70 - - - - - - - -
NHMLFFNE_00363 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NHMLFFNE_00364 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NHMLFFNE_00365 3.68e-163 ybbR - - S - - - YbbR-like protein
NHMLFFNE_00366 6.61e-195 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NHMLFFNE_00367 0.0 fucP - - G ko:K02429 - ko00000,ko02000 Major Facilitator Superfamily
NHMLFFNE_00368 1.01e-87 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
NHMLFFNE_00369 2.07e-210 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NHMLFFNE_00370 6.77e-216 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
NHMLFFNE_00371 1.24e-131 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
NHMLFFNE_00372 6.13e-100 XK27_04775 - - S ko:K09155 - ko00000 PAS domain
NHMLFFNE_00373 1.03e-112 - - - K - - - Acetyltransferase (GNAT) domain
NHMLFFNE_00374 2.42e-105 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
NHMLFFNE_00376 4.55e-109 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
NHMLFFNE_00377 1.05e-199 tex - - K ko:K06959 - ko00000 Tex-like protein N-terminal domain protein
NHMLFFNE_00378 8.34e-165 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
NHMLFFNE_00379 7.27e-198 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NHMLFFNE_00380 1.11e-78 - - - S - - - mazG nucleotide pyrophosphohydrolase
NHMLFFNE_00381 2.01e-139 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
NHMLFFNE_00382 4.84e-296 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NHMLFFNE_00383 5.31e-301 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NHMLFFNE_00384 4.94e-288 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NHMLFFNE_00385 9.84e-206 - - - S - - - Tetratricopeptide repeat
NHMLFFNE_00386 3.23e-75 - - - S - - - Small secreted protein
NHMLFFNE_00387 3.46e-115 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
NHMLFFNE_00388 1.56e-70 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
NHMLFFNE_00389 7.79e-145 - - - M - - - domain protein
NHMLFFNE_00390 6.32e-69 - - - M - - - domain protein
NHMLFFNE_00392 5.87e-180 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NHMLFFNE_00393 1.26e-82 psiE - - S ko:K13256 - ko00000 Phosphate-starvation-inducible E
NHMLFFNE_00394 5.01e-126 nhaP3 - - P ko:K03316 - ko00000 Sodium proton antiporter
NHMLFFNE_00395 1.5e-117 nhaP3 - - P ko:K03316 - ko00000 Sodium proton antiporter
NHMLFFNE_00397 1.02e-279 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
NHMLFFNE_00398 3.7e-72 - - - - - - - -
NHMLFFNE_00399 4.36e-18 frnE 5.3.4.1 - Q ko:K01829 - ko00000,ko01000 DSBA-like thioredoxin domain
NHMLFFNE_00400 1.88e-70 frnE 5.3.4.1 - Q ko:K01829 - ko00000,ko01000 DSBA-like thioredoxin domain
NHMLFFNE_00401 1.22e-112 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
NHMLFFNE_00402 2.32e-145 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
NHMLFFNE_00403 1.08e-215 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
NHMLFFNE_00404 4.67e-234 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
NHMLFFNE_00405 4.71e-200 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NHMLFFNE_00406 3.96e-226 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NHMLFFNE_00407 1.88e-68 yvlD - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
NHMLFFNE_00408 3.65e-67 - - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain protein
NHMLFFNE_00409 7.5e-237 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NHMLFFNE_00410 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NHMLFFNE_00411 3.24e-120 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NHMLFFNE_00412 7.29e-106 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
NHMLFFNE_00413 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
NHMLFFNE_00414 1.63e-145 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
NHMLFFNE_00415 7.83e-302 - - - EGP - - - Major Facilitator
NHMLFFNE_00416 3.07e-89 - - - K - - - Transcriptional regulator
NHMLFFNE_00417 3.74e-53 - - - - - - - -
NHMLFFNE_00418 0.0 ydaO - - E - - - amino acid
NHMLFFNE_00419 0.0 - - - E - - - amino acid
NHMLFFNE_00420 2.24e-301 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
NHMLFFNE_00421 6.08e-54 ureD - - O ko:K03190 - ko00000 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
NHMLFFNE_00422 1.28e-83 ureG - - KO ko:K03189 - ko00000 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
NHMLFFNE_00423 2.6e-40 ureG - - KO ko:K03189 - ko00000 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
NHMLFFNE_00424 9.53e-45 ureF - - O ko:K03188 - ko00000 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
NHMLFFNE_00425 4.16e-198 - - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
NHMLFFNE_00426 2.27e-107 - - - L - - - Belongs to the 'phage' integrase family
NHMLFFNE_00429 3.61e-94 - - - E - - - IrrE N-terminal-like domain
NHMLFFNE_00430 4.72e-61 - - - K - - - Cro/C1-type HTH DNA-binding domain
NHMLFFNE_00431 7.91e-23 - - - K - - - Helix-turn-helix XRE-family like proteins
NHMLFFNE_00433 3.81e-165 tnp2 - - L - - - PFAM Transposase, IS204 IS1001 IS1096 IS1165
NHMLFFNE_00434 3.92e-49 tnp2 - - L - - - PFAM Transposase, IS204 IS1001 IS1096 IS1165
NHMLFFNE_00435 6e-216 hdhL 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
NHMLFFNE_00444 1.95e-225 cytR - - K ko:K02529,ko:K03604 - ko00000,ko03000 Transcriptional regulator, LacI family
NHMLFFNE_00453 7.03e-216 psaA - - P ko:K02077,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
NHMLFFNE_00454 9.8e-158 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
NHMLFFNE_00455 3.54e-165 - - - U ko:K02075 - ko00000,ko00002,ko02000 ABC 3 transport family
NHMLFFNE_00456 2.13e-190 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
NHMLFFNE_00457 6.39e-314 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NHMLFFNE_00458 2.55e-225 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NHMLFFNE_00459 4.24e-101 - - - - - - - -
NHMLFFNE_00460 9.38e-190 yidA - - S - - - hydrolase
NHMLFFNE_00461 0.0 ywfO - - S ko:K06885 - ko00000 HD domain protein
NHMLFFNE_00462 6.84e-188 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 biotin lipoate A B protein ligase
NHMLFFNE_00463 4.42e-87 ywiB - - S - - - Domain of unknown function (DUF1934)
NHMLFFNE_00464 4.32e-82 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NHMLFFNE_00465 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NHMLFFNE_00466 9.15e-301 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NHMLFFNE_00467 9.43e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
NHMLFFNE_00468 1.52e-301 pts13C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NHMLFFNE_00469 4.38e-211 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
NHMLFFNE_00470 1.23e-161 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
NHMLFFNE_00472 0.0 nhaK - - P ko:K03316 - ko00000 Sodium proton antiporter
NHMLFFNE_00473 2.18e-69 - - - - - - - -
NHMLFFNE_00474 3.54e-148 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
NHMLFFNE_00475 3.3e-314 - - - S ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NHMLFFNE_00476 1.81e-128 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
NHMLFFNE_00477 4.76e-56 - - - S ko:K07090 - ko00000 membrane transporter protein
NHMLFFNE_00478 1.1e-89 - - - S ko:K07090 - ko00000 membrane transporter protein
NHMLFFNE_00479 4.88e-176 int2 - - L - - - Belongs to the 'phage' integrase family
NHMLFFNE_00480 6.36e-75 - - - - - - - -
NHMLFFNE_00492 9.78e-81 - - - L - - - transposase IS116 IS110 IS902 family protein
NHMLFFNE_00493 1.91e-200 - - - U ko:K05340 - ko00000,ko02000 sugar transport
NHMLFFNE_00495 2.81e-05 - - - N - - - S-layer homology domain
NHMLFFNE_00496 1.11e-25 ybjQ - - S - - - Belongs to the UPF0145 family
NHMLFFNE_00497 8.95e-223 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
NHMLFFNE_00499 3.12e-311 spoIIQ - - M ko:K06386 - ko00000 Peptidase family M23
NHMLFFNE_00500 5.31e-204 - - - S - - - Phage tail protein
NHMLFFNE_00501 0.0 - - - L - - - Phage tail tape measure protein TP901
NHMLFFNE_00502 8.23e-28 - - - - - - - -
NHMLFFNE_00504 1.19e-142 - - - - - - - -
NHMLFFNE_00505 1.34e-98 - - - - - - - -
NHMLFFNE_00506 2.63e-73 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
NHMLFFNE_00507 1.57e-54 - - - S - - - Phage head-tail joining protein
NHMLFFNE_00508 3.72e-86 - - - S - - - Phage gp6-like head-tail connector protein
NHMLFFNE_00509 5.31e-199 - - - S - - - Phage capsid family
NHMLFFNE_00510 2.29e-144 - - - S ko:K06904 - ko00000 Caudovirus prohead serine protease
NHMLFFNE_00511 4.79e-141 - - - S - - - Phage portal protein
NHMLFFNE_00512 2.18e-134 - - - S - - - Phage portal protein
NHMLFFNE_00515 0.0 terL - - S - - - overlaps another CDS with the same product name
NHMLFFNE_00516 2.81e-101 - - - L - - - Phage terminase, small subunit
NHMLFFNE_00517 4.19e-190 - - - L - - - HNH nucleases
NHMLFFNE_00520 1.01e-294 - - - P - - - Chloride transporter, ClC family
NHMLFFNE_00521 1.06e-148 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
NHMLFFNE_00522 1.75e-189 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
NHMLFFNE_00523 2.77e-180 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NHMLFFNE_00524 4.3e-68 - - - - - - - -
NHMLFFNE_00525 3.26e-170 - - - S - - - SEC-C Motif Domain Protein
NHMLFFNE_00526 2.99e-248 - - - S - - - SEC-C Motif Domain Protein
NHMLFFNE_00527 2.7e-146 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NHMLFFNE_00528 2.12e-172 mhpD - - Q ko:K02509 ko00350,ko01120,map00350,map01120 ko00000,ko00001,ko01000 hydratase
NHMLFFNE_00529 4.8e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NHMLFFNE_00531 1.97e-63 - - - - - - - -
NHMLFFNE_00532 6.21e-133 - - - M - - - hydrolase, family 25
NHMLFFNE_00534 6.92e-38 - - - V - - - NUMOD4 motif
NHMLFFNE_00535 7.61e-116 ymdB - - S - - - Macro domain protein
NHMLFFNE_00536 2.03e-38 - - - K - - - helix_turn_helix, mercury resistance
NHMLFFNE_00538 1.54e-146 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
NHMLFFNE_00539 2.78e-75 - 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase, GNAT family
NHMLFFNE_00540 3.22e-71 - - - S - - - reductase
NHMLFFNE_00541 1.73e-101 - - - S - - - reductase
NHMLFFNE_00543 0.0 - - - S - - - amidohydrolase
NHMLFFNE_00544 0.0 - - - K - - - Aminotransferase class I and II
NHMLFFNE_00547 1.53e-49 - - - - - - - -
NHMLFFNE_00548 0.0 - - - S ko:K06909 - ko00000 Phage terminase, large subunit
NHMLFFNE_00549 0.0 - - - S - - - Phage portal protein, SPP1 Gp6-like
NHMLFFNE_00550 7.64e-222 - - - S - - - Phage Mu protein F like protein
NHMLFFNE_00551 3.17e-115 - - - S - - - Domain of unknown function (DUF4355)
NHMLFFNE_00552 7.52e-75 gpG - - - - - - -
NHMLFFNE_00553 1.76e-157 gpG - - - - - - -
NHMLFFNE_00554 6.53e-77 - - - S - - - Phage gp6-like head-tail connector protein
NHMLFFNE_00555 1.8e-66 - - - - - - - -
NHMLFFNE_00556 6.99e-117 - - - - - - - -
NHMLFFNE_00557 1.52e-89 - - - - - - - -
NHMLFFNE_00558 1.69e-145 - - - - - - - -
NHMLFFNE_00559 1.87e-114 - - - S - - - Phage tail assembly chaperone protein, TAC
NHMLFFNE_00560 0.0 - - - D - - - domain protein
NHMLFFNE_00561 1.97e-123 - - - S - - - Phage tail protein
NHMLFFNE_00562 2.08e-248 - - - S - - - Peptidase family M23
NHMLFFNE_00563 5.12e-101 ureE - - O ko:K03187 - ko00000 Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
NHMLFFNE_00564 4.51e-78 ureF - - O ko:K03188 - ko00000 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
NHMLFFNE_00566 1.19e-91 azlC - - E - - - azaleucine resistance protein AzlC
NHMLFFNE_00567 5.48e-48 azlC - - E - - - azaleucine resistance protein AzlC
NHMLFFNE_00568 1.48e-163 - - - O - - - Bacterial dnaA protein
NHMLFFNE_00571 7.01e-184 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
NHMLFFNE_00572 4.81e-169 - - - O - - - Bacterial dnaA protein
NHMLFFNE_00573 2.5e-153 yagB - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
NHMLFFNE_00574 2.64e-36 - - - S - - - Sulphur transport
NHMLFFNE_00575 3.75e-177 - - - P - - - Rhodanese Homology Domain
NHMLFFNE_00576 4.29e-19 - - - O - - - Belongs to the sulfur carrier protein TusA family
NHMLFFNE_00577 6.96e-107 - - - S - - - Sulfite exporter TauE/SafE
NHMLFFNE_00578 8.17e-29 - - - S - - - Sulfite exporter TauE/SafE
NHMLFFNE_00579 1.54e-53 - - - O - - - Belongs to the sulfur carrier protein TusA family
NHMLFFNE_00580 5.54e-246 - - - S ko:K07112 - ko00000 Sulphur transport
NHMLFFNE_00581 2.42e-205 selA 2.9.1.1 - H ko:K01042 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko01000 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis
NHMLFFNE_00582 5.15e-208 - - - E - - - Beta-eliminating lyase
NHMLFFNE_00583 3.94e-289 selB - - J ko:K03833 - ko00000,ko03012 Elongation factor SelB, winged helix
NHMLFFNE_00584 2.42e-38 - - - S - - - Protein of unknown function (DUF3343)
NHMLFFNE_00585 1.79e-99 yedF - - O - - - Belongs to the sulfur carrier protein TusA family
NHMLFFNE_00586 1.06e-197 selD 2.7.9.3 - H ko:K01008 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000,ko03016 Synthesizes selenophosphate from selenide and ATP
NHMLFFNE_00587 1.25e-156 - - - S - - - Sulfite exporter TauE/SafE
NHMLFFNE_00588 5.22e-215 - 5.1.1.4 - E ko:K01777 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko01000 Proline racemase
NHMLFFNE_00589 2.9e-96 - - - EJ - - - Glycine/sarcosine/betaine reductase component B subunits
NHMLFFNE_00590 4.28e-139 - - - S - - - An automated process has identified a potential problem with this gene model
NHMLFFNE_00591 3.83e-42 - - - S - - - the current gene model (or a revised gene model) may contain a premature stop
NHMLFFNE_00592 8.81e-98 prdB - - S - - - the current gene model (or a revised gene model) may contain a premature stop
NHMLFFNE_00593 4.13e-67 - - - S - - - Psort location Cytoplasmic, score
NHMLFFNE_00594 0.0 prdA 1.21.4.1 - EJ ko:K10793 ko00330,map00330 ko00000,ko00001,ko01000 Glycine/sarcosine/betaine reductase component B subunits
NHMLFFNE_00595 3.83e-170 pepI 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
NHMLFFNE_00597 9.53e-84 dtpT - - P ko:K03305 - ko00000 POT family
NHMLFFNE_00598 1.1e-38 dtpT - - P ko:K03305 - ko00000 POT family
NHMLFFNE_00599 1.79e-33 dtpT - - P ko:K03305 - ko00000 POT family
NHMLFFNE_00600 6.38e-297 - - - C - - - RnfC Barrel sandwich hybrid domain
NHMLFFNE_00601 1.81e-41 - - - - - - - -
NHMLFFNE_00602 3.8e-63 - - - - - - - -
NHMLFFNE_00603 2.3e-63 - - - K - - - Acetyltransferase (GNAT) domain
NHMLFFNE_00604 1.31e-48 - - - K - - - Acetyltransferase (GNAT) domain
NHMLFFNE_00605 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
NHMLFFNE_00606 1.19e-19 gntP - - EG ko:K03299 - ko00000,ko02000 Gluconate
NHMLFFNE_00607 6.56e-135 - - - M - - - hydrolase, family 25
NHMLFFNE_00608 2.34e-113 ebsC - - J ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NHMLFFNE_00609 0.0 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
NHMLFFNE_00610 0.0 yfiC - - V ko:K06147 - ko00000,ko02000 ABC transporter
NHMLFFNE_00611 0.0 ycfI - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
NHMLFFNE_00614 2.37e-31 - - - S - - - Bacteriophage holin of superfamily 6 (Holin_LLH)
NHMLFFNE_00618 3.77e-95 - - - K - - - Transcriptional regulator, TetR family
NHMLFFNE_00619 5.47e-103 usp5 - - T - - - universal stress protein
NHMLFFNE_00620 1.62e-62 - - - S - - - Protein of unknown function (DUF3102)
NHMLFFNE_00621 7.46e-149 - - - S - - - HAD hydrolase, family IA, variant
NHMLFFNE_00622 1e-166 yagE - - E - - - amino acid
NHMLFFNE_00623 2.38e-121 yagE - - E - - - amino acid
NHMLFFNE_00624 1.98e-110 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
NHMLFFNE_00625 0.0 atp2C1 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
NHMLFFNE_00629 9.06e-260 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NHMLFFNE_00630 8.05e-277 - - - L - - - DNA helicase
NHMLFFNE_00631 3.45e-186 - - - L - - - DNA helicase
NHMLFFNE_00632 1.03e-41 - - - L - - - DNA helicase
NHMLFFNE_00633 7.04e-107 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Belongs to the NDK family
NHMLFFNE_00634 2.61e-235 - 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 Belongs to the N(4) N(6)-methyltransferase family
NHMLFFNE_00635 5.54e-243 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
NHMLFFNE_00636 7.81e-213 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
NHMLFFNE_00637 1.37e-288 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
NHMLFFNE_00638 8.62e-225 - - - - - - - -
NHMLFFNE_00639 2.4e-167 cobB - - K ko:K12410 - ko00000,ko01000 SIR2 family
NHMLFFNE_00641 4.55e-206 yunF - - F - - - Protein of unknown function DUF72
NHMLFFNE_00642 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NHMLFFNE_00643 2.94e-197 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
NHMLFFNE_00644 1.73e-127 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NHMLFFNE_00645 1.34e-201 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NHMLFFNE_00646 2.74e-50 veg - - S - - - Biofilm formation stimulator VEG
NHMLFFNE_00647 4.72e-204 ispE 2.7.1.148 - F ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NHMLFFNE_00653 2.99e-114 - - - L ko:K07497 - ko00000 hmm pf00665
NHMLFFNE_00654 4.31e-30 - - - - - - - -
NHMLFFNE_00655 1.1e-276 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 transporter
NHMLFFNE_00656 1.3e-58 - 1.3.5.4 - S ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FMN binding
NHMLFFNE_00657 4.89e-153 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NHMLFFNE_00658 3.98e-92 ctrA - - E ko:K03294 - ko00000 amino acid
NHMLFFNE_00659 9.59e-190 ctrA - - E ko:K03294 - ko00000 amino acid
NHMLFFNE_00660 0.0 gabT 2.6.1.19, 5.1.1.21 - E ko:K00823,ko:K20708 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NHMLFFNE_00662 3.73e-62 - - - - - - - -
NHMLFFNE_00663 7.59e-18 - - - - - - - -
NHMLFFNE_00667 7.21e-164 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NHMLFFNE_00668 6.77e-269 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
NHMLFFNE_00669 2.52e-148 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NHMLFFNE_00670 2.7e-47 ynzC - - S - - - UPF0291 protein
NHMLFFNE_00671 1.6e-40 XK26_06720 - - S ko:K09976 - ko00000 Uncharacterised protein family (UPF0154)
NHMLFFNE_00672 1.07e-151 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
NHMLFFNE_00673 1.14e-179 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
NHMLFFNE_00674 2.77e-64 yazA - - L ko:K07461 - ko00000 GIY-YIG catalytic domain protein
NHMLFFNE_00675 9.78e-123 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NHMLFFNE_00676 2.81e-39 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NHMLFFNE_00677 3.54e-184 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
NHMLFFNE_00678 3.14e-197 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NHMLFFNE_00679 2.97e-167 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
NHMLFFNE_00680 2.86e-121 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NHMLFFNE_00681 3.16e-183 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NHMLFFNE_00682 2.03e-178 cdsA 2.7.7.41 - I ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
NHMLFFNE_00683 5.46e-297 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
NHMLFFNE_00684 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NHMLFFNE_00685 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NHMLFFNE_00686 5.44e-109 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
NHMLFFNE_00687 6.83e-274 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
NHMLFFNE_00688 4.02e-58 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
NHMLFFNE_00689 5.4e-63 ylxQ - - J - - - ribosomal protein
NHMLFFNE_00690 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NHMLFFNE_00691 1.62e-76 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NHMLFFNE_00692 8.55e-216 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NHMLFFNE_00693 9.36e-227 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
NHMLFFNE_00694 3.61e-84 - - - - - - - -
NHMLFFNE_00695 7.6e-246 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NHMLFFNE_00696 8.31e-111 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NHMLFFNE_00697 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
NHMLFFNE_00698 5.41e-274 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NHMLFFNE_00699 0.0 pps 2.7.9.2 - H ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
NHMLFFNE_00700 1.63e-166 - - - G - - - Right handed beta helix region
NHMLFFNE_00702 3.37e-176 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NHMLFFNE_00703 2.35e-209 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
NHMLFFNE_00704 1.24e-153 - - - G - - - Belongs to the phosphoglycerate mutase family
NHMLFFNE_00705 2.32e-113 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NHMLFFNE_00706 7e-123 lemA - - S ko:K03744 - ko00000 LemA family
NHMLFFNE_00707 7.47e-204 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
NHMLFFNE_00708 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NHMLFFNE_00709 0.0 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NHMLFFNE_00710 1.35e-69 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
NHMLFFNE_00711 5.76e-174 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
NHMLFFNE_00712 3.13e-153 - - - D - - - Domain of Unknown Function (DUF1542)
NHMLFFNE_00713 5.07e-242 - - - D - - - Domain of Unknown Function (DUF1542)
NHMLFFNE_00721 5.76e-66 - - - - - - - -
NHMLFFNE_00722 1.5e-170 XK27_07210 - - S - - - B3 4 domain
NHMLFFNE_00723 8.16e-103 yybA - - K - - - Transcriptional regulator
NHMLFFNE_00724 2.14e-117 - - - K - - - Domain of unknown function (DUF1836)
NHMLFFNE_00725 2.22e-114 - - - GM - - - epimerase
NHMLFFNE_00726 2.81e-198 - - - V - - - (ABC) transporter
NHMLFFNE_00727 8.65e-310 yhdP - - S - - - Transporter associated domain
NHMLFFNE_00728 3.29e-109 nrdI - - F ko:K03647 - ko00000 Belongs to the NrdI family
NHMLFFNE_00729 1.17e-74 - - - F ko:K03647 - ko00000 Belongs to the NrdI family
NHMLFFNE_00733 1.09e-05 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
NHMLFFNE_00735 5.28e-28 - - - M - - - CHAP domain
NHMLFFNE_00737 9.79e-120 - - - M - - - NlpC/P60 family
NHMLFFNE_00738 1.44e-36 - - - S - - - Bacteriophage Gp15 protein
NHMLFFNE_00740 6.29e-47 - - - N - - - domain, Protein
NHMLFFNE_00741 1.52e-12 - - - S - - - Minor capsid protein from bacteriophage
NHMLFFNE_00743 1.25e-37 - - - S - - - Minor capsid protein
NHMLFFNE_00745 2.02e-131 - - - - - - - -
NHMLFFNE_00746 7.17e-28 - - - S - - - Phage minor structural protein GP20
NHMLFFNE_00747 5.8e-114 - - - S - - - Phage minor capsid protein 2
NHMLFFNE_00748 1.1e-165 - - - S - - - Phage portal protein, SPP1 Gp6-like
NHMLFFNE_00749 5.36e-174 - - - S - - - Pfam:Terminase_3C
NHMLFFNE_00750 5.71e-63 - - - L ko:K07474 - ko00000 Terminase small subunit
NHMLFFNE_00752 1.99e-96 nqo1 - - S ko:K19784 - ko00000 NADPH-dependent FMN reductase
NHMLFFNE_00753 9.43e-73 nqo1 - - S ko:K19784 - ko00000 NADPH-dependent FMN reductase
NHMLFFNE_00754 2.54e-101 ykuP - - C ko:K03839 - ko00000 Flavodoxin
NHMLFFNE_00755 3.52e-91 eutP - - E ko:K04029 - ko00000 Ethanolamine utilisation - propanediol utilisation
NHMLFFNE_00756 3.35e-119 - - - P - - - Cadmium resistance transporter
NHMLFFNE_00757 5.12e-74 pgm1 - - G - - - phosphoglycerate mutase
NHMLFFNE_00758 4.17e-50 pgm1 - - G - - - phosphoglycerate mutase
NHMLFFNE_00759 6.84e-183 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Pfam:Y_phosphatase3C
NHMLFFNE_00760 9.52e-74 - - - E ko:K04031 - ko00000 BMC
NHMLFFNE_00761 3.56e-278 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NHMLFFNE_00762 1.26e-267 pduQ - - C ko:K13921 ko00640,map00640 ko00000,ko00001 Iron-containing alcohol dehydrogenase
NHMLFFNE_00763 0.0 pduP 1.2.1.87 - C ko:K13922 ko00640,map00640 ko00000,ko00001,ko01000 Aldehyde dehydrogenase family
NHMLFFNE_00764 1.01e-104 pduO - - S - - - Haem-degrading
NHMLFFNE_00765 2.55e-137 - - - S - - - Cobalamin adenosyltransferase
NHMLFFNE_00766 1.96e-55 pduN - - CQ ko:K04028 - ko00000 Ethanolamine utilisation protein EutN/carboxysome
NHMLFFNE_00767 1.86e-114 - - - S - - - Putative propanediol utilisation
NHMLFFNE_00768 1.77e-151 pduL 2.3.1.222 - Q ko:K13923 ko00640,map00640 ko00000,ko00001,ko01000 Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate
NHMLFFNE_00769 4.11e-57 pduA_2 - - CQ ko:K04027 - ko00000 BMC
NHMLFFNE_00770 1.97e-84 - - - CQ - - - BMC
NHMLFFNE_00771 2.86e-10 - - - CQ - - - BMC
NHMLFFNE_00772 2.9e-79 pduH - - S - - - Dehydratase medium subunit
NHMLFFNE_00773 0.0 pduG - - D - - - Diol dehydratase reactivase ATPase-like domain
NHMLFFNE_00774 5.2e-105 pduE 4.2.1.28 - Q ko:K13920 ko00640,map00640 ko00000,ko00001,ko01000 Dehydratase small subunit
NHMLFFNE_00775 1.82e-164 pduD 4.2.1.28 - Q ko:K13919 ko00640,map00640 ko00000,ko00001,ko01000 Dehydratase medium subunit
NHMLFFNE_00776 0.0 pduC 4.2.1.28 - Q ko:K01699 ko00640,map00640 ko00000,ko00001,ko01000 Dehydratase large subunit
NHMLFFNE_00777 3.41e-170 pduB - - E - - - BMC
NHMLFFNE_00778 2.72e-56 - - - CQ - - - BMC
NHMLFFNE_00779 1.1e-254 - - - K - - - helix_turn_helix, arabinose operon control protein
NHMLFFNE_00780 2.96e-107 eutJ - - E ko:K04024 - ko00000 Hsp70 protein
NHMLFFNE_00781 4.17e-174 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
NHMLFFNE_00782 1.9e-204 - - - - - - - -
NHMLFFNE_00783 5.91e-197 - - - G - - - Xylose isomerase domain protein TIM barrel
NHMLFFNE_00784 1.1e-238 XK27_12525 - - S - - - AI-2E family transporter
NHMLFFNE_00790 5.22e-31 - - - S - - - Domain of unknown function (DUF4145)
NHMLFFNE_00793 1.22e-18 - - - - - - - -
NHMLFFNE_00794 2.5e-26 - - - S - - - Domain of unknown function (DUF771)
NHMLFFNE_00796 4.43e-43 - - - S - - - Hypothetical protein (DUF2513)
NHMLFFNE_00799 1.1e-09 - - - K - - - Helix-turn-helix XRE-family like proteins
NHMLFFNE_00800 1.35e-27 - - - K - - - Helix-turn-helix domain
NHMLFFNE_00803 1.49e-25 - - - - - - - -
NHMLFFNE_00806 1.17e-143 - - - - - - - -
NHMLFFNE_00807 2.81e-281 int - - L ko:K06400 - ko00000 COG1961 Site-specific recombinases, DNA invertase Pin homologs
NHMLFFNE_00808 1.18e-76 gntP - - EG ko:K03299 - ko00000,ko02000 Gluconate
NHMLFFNE_00809 2.46e-93 gntP - - EG ko:K03299 - ko00000,ko02000 Gluconate
NHMLFFNE_00810 4.12e-234 - - - K ko:K02525 - ko00000,ko03000 Transcriptional regulator, LacI family
NHMLFFNE_00811 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
NHMLFFNE_00812 8.01e-125 - - - - - - - -
NHMLFFNE_00813 1.04e-33 - - - - - - - -
NHMLFFNE_00814 1.63e-82 asp1 - - S - - - Asp23 family, cell envelope-related function
NHMLFFNE_00815 1.8e-115 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
NHMLFFNE_00817 6.19e-64 - - - - - - - -
NHMLFFNE_00818 6.1e-88 - - - S - - - Belongs to the HesB IscA family
NHMLFFNE_00819 3.75e-31 - - - L - - - Integrase
NHMLFFNE_00820 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
NHMLFFNE_00821 3.08e-123 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NHMLFFNE_00822 3.88e-204 rrmA 2.1.1.187 - H ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 Methyltransferase
NHMLFFNE_00823 8.81e-241 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
NHMLFFNE_00825 1.29e-168 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
NHMLFFNE_00826 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NHMLFFNE_00827 2.21e-311 yycH - - S - - - YycH protein
NHMLFFNE_00828 6.12e-194 yycI - - S - - - YycH protein
NHMLFFNE_00829 1.7e-194 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
NHMLFFNE_00830 1.58e-283 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
NHMLFFNE_00831 9.62e-116 pgpA - - I - - - Phosphatidylglycerophosphatase A
NHMLFFNE_00832 8.16e-134 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
NHMLFFNE_00833 9.87e-73 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
NHMLFFNE_00834 2.16e-114 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NHMLFFNE_00835 5.24e-124 - - - S - - - reductase
NHMLFFNE_00836 1.53e-288 dhaT 1.1.1.202 - C ko:K00086 ko00561,ko00640,map00561,map00640 ko00000,ko00001,ko01000 Dehydrogenase
NHMLFFNE_00837 7.89e-162 - - - E - - - Glyoxalase-like domain
NHMLFFNE_00838 6.84e-186 - 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NHMLFFNE_00839 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
NHMLFFNE_00840 9.18e-317 steT - - E ko:K03294 - ko00000 amino acid
NHMLFFNE_00841 8.05e-208 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
NHMLFFNE_00842 2.43e-240 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
NHMLFFNE_00843 1.37e-218 whiA - - K ko:K09762 - ko00000 May be required for sporulation
NHMLFFNE_00845 1.06e-20 - - - - - - - -
NHMLFFNE_00847 3.97e-19 - - - M - - - Rib/alpha-like repeat
NHMLFFNE_00848 0.0 - - - M - - - Rib/alpha-like repeat
NHMLFFNE_00850 1.01e-244 - - - M - - - Rib/alpha-like repeat
NHMLFFNE_00851 0.0 - - - M - - - Rib/alpha-like repeat
NHMLFFNE_00852 1.14e-124 - - - M - - - Rib/alpha-like repeat
NHMLFFNE_00853 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
NHMLFFNE_00854 1.69e-32 - - - IQ - - - Enoyl-(Acyl carrier protein) reductase
NHMLFFNE_00855 1.7e-40 - - - IQ - - - dehydrogenase reductase
NHMLFFNE_00856 1.63e-33 - - - K - - - Bacterial transcriptional regulator
NHMLFFNE_00858 6.69e-162 pgm3 - - G - - - phosphoglycerate mutase family
NHMLFFNE_00859 2.07e-55 - - - - - - - -
NHMLFFNE_00860 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NHMLFFNE_00861 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
NHMLFFNE_00862 1.51e-234 lacM 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase
NHMLFFNE_00863 0.0 - - - S - - - Bacterial membrane protein, YfhO
NHMLFFNE_00864 1.24e-171 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NHMLFFNE_00865 2.19e-216 - - - I - - - alpha/beta hydrolase fold
NHMLFFNE_00866 6.07e-274 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
NHMLFFNE_00867 3.36e-154 tcyB - - E ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NHMLFFNE_00868 3.52e-173 - - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NHMLFFNE_00869 8.99e-181 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
NHMLFFNE_00870 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
NHMLFFNE_00871 1.02e-161 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NHMLFFNE_00872 4.04e-67 yjdJ - - S ko:K06975 - ko00000 GCN5-related N-acetyl-transferase
NHMLFFNE_00873 2.31e-127 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
NHMLFFNE_00874 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NHMLFFNE_00875 2.09e-265 yacL - - S - - - domain protein
NHMLFFNE_00876 0.0 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NHMLFFNE_00877 1.02e-181 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NHMLFFNE_00878 1.26e-288 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
NHMLFFNE_00879 1.31e-243 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NHMLFFNE_00881 4.07e-13 - - - - - - - -
NHMLFFNE_00882 3.27e-229 - - - S ko:K06889 - ko00000 Hydrolases of the alpha beta superfamily
NHMLFFNE_00883 1.8e-249 adhP 1.1.1.1 - C ko:K00001,ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
NHMLFFNE_00884 2.81e-101 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
NHMLFFNE_00885 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NHMLFFNE_00886 2.09e-143 - - - K - - - Bacterial regulatory proteins, tetR family
NHMLFFNE_00887 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NHMLFFNE_00888 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NHMLFFNE_00889 1.83e-260 - - - - - - - -
NHMLFFNE_00890 1.97e-79 fusA1 - - J - - - elongation factor G
NHMLFFNE_00891 2.17e-213 - - - GK - - - ROK family
NHMLFFNE_00892 1.88e-308 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
NHMLFFNE_00893 2.6e-179 yfhR3 - - S ko:K06889 - ko00000 Serine hydrolase (FSH1)
NHMLFFNE_00894 5.96e-61 - - - E - - - amino acid
NHMLFFNE_00895 9.1e-208 - - - E - - - amino acid
NHMLFFNE_00897 3.28e-201 - - - - - - - -
NHMLFFNE_00898 1.21e-222 - - - - - - - -
NHMLFFNE_00899 1.3e-110 - - - S - - - Protein conserved in bacteria
NHMLFFNE_00902 5.7e-146 - - - K - - - Transcriptional regulator
NHMLFFNE_00903 2.68e-67 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
NHMLFFNE_00904 1.77e-72 ysxB - - J ko:K07584 - ko00000 Cysteine protease Prp
NHMLFFNE_00905 7.2e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
NHMLFFNE_00906 1.05e-204 - - - L - - - Belongs to the 'phage' integrase family
NHMLFFNE_00907 2.81e-36 - - - L - - - Belongs to the 'phage' integrase family
NHMLFFNE_00908 1.94e-66 - - - - - - - -
NHMLFFNE_00909 1.43e-173 XK27_05695 - - V ko:K02003,ko:K19083 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NHMLFFNE_00910 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
NHMLFFNE_00911 4.03e-201 metA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
NHMLFFNE_00912 3.64e-210 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
NHMLFFNE_00913 3.12e-195 - - - EG - - - EamA-like transporter family
NHMLFFNE_00914 4.68e-168 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase
NHMLFFNE_00915 7.01e-129 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase molybdenum cofactor assembly chaperone
NHMLFFNE_00916 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 4Fe-4S dicluster domain
NHMLFFNE_00917 0.0 narZ 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NHMLFFNE_00918 9.1e-237 moeB 2.7.7.80 - H ko:K21029 ko04122,map04122 ko00000,ko00001,ko01000 ThiF family
NHMLFFNE_00919 1.42e-108 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
NHMLFFNE_00920 4.54e-284 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 MoeA N-terminal region (domain I and II)
NHMLFFNE_00921 2.63e-96 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
NHMLFFNE_00922 3.21e-124 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
NHMLFFNE_00923 1.76e-57 - - - - - - - -
NHMLFFNE_00924 4.45e-232 nreB 2.7.13.3 - F ko:K07683 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Sensor histidine kinase
NHMLFFNE_00925 1.02e-147 nreC - - K ko:K07696 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 PFAM regulatory protein LuxR
NHMLFFNE_00926 2.85e-25 - - - - - - - -
NHMLFFNE_00927 6.3e-224 - - - - - - - -
NHMLFFNE_00928 4.26e-182 - - - H - - - geranyltranstransferase activity
NHMLFFNE_00929 6.37e-55 yrzL - - S - - - Belongs to the UPF0297 family
NHMLFFNE_00930 4.23e-99 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NHMLFFNE_00931 3.75e-63 yrzB - - S - - - Belongs to the UPF0473 family
NHMLFFNE_00932 7.15e-122 cvpA - - S - - - Colicin V production protein
NHMLFFNE_00933 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NHMLFFNE_00934 2.86e-72 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
NHMLFFNE_00935 8.71e-176 lutC - - S ko:K00782 - ko00000 LUD domain
NHMLFFNE_00936 0.0 lutB - - C ko:K18929 - ko00000 4Fe-4S dicluster domain
NHMLFFNE_00937 5.35e-213 lutA - - C ko:K18928 - ko00000 Cysteine-rich domain
NHMLFFNE_00938 1.95e-221 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NHMLFFNE_00939 3.15e-276 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
NHMLFFNE_00940 1.15e-205 - - - ET ko:K02030 - ko00000,ko00002,ko02000 PFAM extracellular solute-binding protein, family 3
NHMLFFNE_00941 9.93e-115 ykhA 3.1.2.20 - I ko:K01073 - ko00000,ko01000 Thioesterase superfamily
NHMLFFNE_00942 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
NHMLFFNE_00943 7.21e-150 yfbR - - S ko:K07023 - ko00000 HD containing hydrolase-like enzyme
NHMLFFNE_00944 1.03e-19 - - - - - - - -
NHMLFFNE_00945 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NHMLFFNE_00946 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NHMLFFNE_00947 0.0 snf - - KL - - - domain protein
NHMLFFNE_00948 0.0 snf - - KL - - - domain protein
NHMLFFNE_00951 2.4e-281 arcT - - E - - - Aminotransferase
NHMLFFNE_00952 0.0 arcD - - E ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
NHMLFFNE_00953 0.0 potE - - E - - - Amino Acid
NHMLFFNE_00954 8.71e-202 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
NHMLFFNE_00955 1.47e-45 - - - S - - - Protein of unknown function (DUF2922)
NHMLFFNE_00956 5.12e-42 - - - - - - - -
NHMLFFNE_00957 1.66e-174 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
NHMLFFNE_00958 1.51e-186 cps1D - - M - - - Domain of unknown function (DUF4422)
NHMLFFNE_00959 4.62e-224 yfdH - GT2 M ko:K12999 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
NHMLFFNE_00960 4.01e-153 - - - M - - - Bacterial sugar transferase
NHMLFFNE_00961 0.0 spoIIQ - - M ko:K06386 - ko00000 Peptidase family M23
NHMLFFNE_00962 0.0 - - - G - - - Peptidase_C39 like family
NHMLFFNE_00963 1.45e-36 - - - - - - - -
NHMLFFNE_00964 1.28e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
NHMLFFNE_00965 5.45e-153 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NHMLFFNE_00966 6.64e-139 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
NHMLFFNE_00967 3.61e-61 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NHMLFFNE_00968 1.16e-203 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NHMLFFNE_00969 5.72e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NHMLFFNE_00970 4.36e-70 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NHMLFFNE_00971 9.81e-157 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NHMLFFNE_00972 1.96e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NHMLFFNE_00973 5.49e-38 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
NHMLFFNE_00974 1.1e-55 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NHMLFFNE_00975 3.62e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NHMLFFNE_00976 2.58e-65 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NHMLFFNE_00977 7.42e-125 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NHMLFFNE_00978 4.97e-40 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NHMLFFNE_00979 1.54e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NHMLFFNE_00980 2.6e-124 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NHMLFFNE_00981 5.03e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NHMLFFNE_00982 5.95e-112 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NHMLFFNE_00983 5.94e-34 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
NHMLFFNE_00984 6.05e-93 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
NHMLFFNE_00985 2.36e-305 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NHMLFFNE_00986 4.52e-161 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NHMLFFNE_00987 2.41e-45 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NHMLFFNE_00988 5.79e-21 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
NHMLFFNE_00989 1.54e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NHMLFFNE_00990 2.3e-83 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NHMLFFNE_00991 2.19e-220 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NHMLFFNE_00992 9.44e-82 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
NHMLFFNE_00993 2.76e-183 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NHMLFFNE_00994 1.08e-188 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NHMLFFNE_00995 3.76e-177 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NHMLFFNE_00996 1.29e-183 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NHMLFFNE_00997 2.27e-103 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NHMLFFNE_00998 3.94e-85 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
NHMLFFNE_00999 6.08e-178 budC 1.1.1.304, 1.1.1.76 - IQ ko:K03366 ko00650,map00650 ko00000,ko00001,ko01000 reductase
NHMLFFNE_01000 3.07e-149 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
NHMLFFNE_01001 2.26e-129 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NHMLFFNE_01002 3.11e-270 purK2 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NHMLFFNE_01003 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
NHMLFFNE_01004 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NHMLFFNE_01005 2.61e-259 camS - - S - - - sex pheromone
NHMLFFNE_01006 9.23e-65 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NHMLFFNE_01007 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NHMLFFNE_01008 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NHMLFFNE_01009 2.4e-235 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
NHMLFFNE_01010 1.79e-159 yjbO 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
NHMLFFNE_01011 9.49e-154 - - - S - - - Domain of unknown function (DUF4811)
NHMLFFNE_01012 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
NHMLFFNE_01013 1.53e-97 - - - K - - - MerR HTH family regulatory protein
NHMLFFNE_01014 1.92e-73 - - - - - - - -
NHMLFFNE_01015 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NHMLFFNE_01016 3.85e-280 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
NHMLFFNE_01017 2.11e-140 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NHMLFFNE_01018 3.03e-142 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NHMLFFNE_01019 1.34e-195 peb1A - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NHMLFFNE_01020 1.14e-172 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NHMLFFNE_01021 2.79e-107 - - - T - - - Belongs to the universal stress protein A family
NHMLFFNE_01022 7.81e-141 - - - S - - - VIT family
NHMLFFNE_01023 5.16e-152 - - - S - - - membrane
NHMLFFNE_01024 4.72e-211 - - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
NHMLFFNE_01025 6.64e-161 mntR - - K ko:K03709 - ko00000,ko03000 iron dependent repressor
NHMLFFNE_01026 1.12e-15 cspC - - K ko:K03704 - ko00000,ko03000 Cold shock protein
NHMLFFNE_01027 8.47e-08 - - - S - - - Cytochrome B5
NHMLFFNE_01028 7.72e-51 - - - S - - - Cytochrome B5
NHMLFFNE_01029 2.77e-94 - - - S ko:K02348 - ko00000 Gnat family
NHMLFFNE_01030 5.48e-157 - - - GM - - - NmrA-like family
NHMLFFNE_01031 1.07e-66 ydeP - - K - - - Transcriptional regulator, HxlR family
NHMLFFNE_01032 2.01e-141 XK27_02070 - - S ko:K07078 - ko00000 Nitroreductase family
NHMLFFNE_01033 1.85e-108 - - - K - - - Transcriptional regulator, HxlR family
NHMLFFNE_01034 1.04e-303 - - - - - - - -
NHMLFFNE_01035 2.18e-268 - - - EGP - - - Major Facilitator Superfamily
NHMLFFNE_01036 0.0 pepE 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
NHMLFFNE_01037 5.89e-145 - - - GM - - - NAD dependent epimerase dehydratase family protein
NHMLFFNE_01038 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
NHMLFFNE_01039 2.82e-115 - - - S - - - ECF transporter, substrate-specific component
NHMLFFNE_01040 1.56e-37 yiaC - - K ko:K03826 - ko00000,ko01000 Acetyltransferase (GNAT) domain
NHMLFFNE_01041 3.51e-253 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
NHMLFFNE_01042 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
NHMLFFNE_01043 7.75e-145 - - - S - - - (CBS) domain
NHMLFFNE_01044 5.62e-132 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NHMLFFNE_01045 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NHMLFFNE_01046 2.89e-52 yabO - - J - - - S4 domain protein
NHMLFFNE_01047 1.69e-73 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
NHMLFFNE_01048 5.75e-103 yabR - - J ko:K07571 - ko00000 RNA binding
NHMLFFNE_01049 0.0 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NHMLFFNE_01050 3.68e-125 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
NHMLFFNE_01051 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NHMLFFNE_01052 2.27e-218 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NHMLFFNE_01053 1.53e-241 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NHMLFFNE_01054 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
NHMLFFNE_01055 2.47e-98 - - - - - - - -
NHMLFFNE_01056 6.62e-260 - - - G - - - Transporter, major facilitator family protein
NHMLFFNE_01057 3.94e-139 - - - K ko:K03091 - ko00000,ko03021 RNA polymerase sigma factor, sigma-70 family
NHMLFFNE_01058 9.54e-85 yuxO - - Q - - - Thioesterase superfamily
NHMLFFNE_01059 2.84e-200 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NHMLFFNE_01060 9.17e-175 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
NHMLFFNE_01061 1.72e-149 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
NHMLFFNE_01062 0.0 feoB - - P ko:K04759 - ko00000,ko02000 transporter of a GTP-driven Fe(2 ) uptake system
NHMLFFNE_01063 9.89e-43 feoA - - P ko:K04758 - ko00000,ko02000 FeoA domain
NHMLFFNE_01064 5.43e-185 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
NHMLFFNE_01065 1.59e-303 sufD - - O ko:K07033,ko:K09015 - ko00000 FeS assembly protein SufD
NHMLFFNE_01066 2.14e-297 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NHMLFFNE_01067 6.17e-104 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
NHMLFFNE_01068 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
NHMLFFNE_01069 1.14e-74 - - - S - - - Iron-sulfur cluster assembly protein
NHMLFFNE_01070 3.86e-205 - - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
NHMLFFNE_01071 7.15e-148 nreC - - K ko:K07696 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 PFAM regulatory protein LuxR
NHMLFFNE_01072 0.0 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NHMLFFNE_01073 1.74e-154 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NHMLFFNE_01074 8.34e-235 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
NHMLFFNE_01075 1.3e-113 - - - K - - - transcriptional regulator (TetR family)
NHMLFFNE_01076 1.5e-156 citR - - K - - - sugar-binding domain protein
NHMLFFNE_01077 1.41e-224 mae 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme, NAD binding domain
NHMLFFNE_01078 3.28e-188 citC 6.2.1.22 - H ko:K01910 ko02020,map02020 ko00000,ko00001,ko01000 Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
NHMLFFNE_01079 2.56e-56 citD - - C ko:K01646 ko02020,map02020 ko00000,ko00001 Covalent carrier of the coenzyme of citrate lyase
NHMLFFNE_01080 3.29e-204 citE 4.1.3.34 - G ko:K01644 ko02020,map02020 ko00000,ko00001,ko01000 Belongs to the HpcH HpaI aldolase family
NHMLFFNE_01081 0.0 citF 2.8.3.10 - H ko:K01643 ko02020,map02020 ko00000,ko00001,ko01000 Citrate (pro-3S)-lyase alpha chain
NHMLFFNE_01082 8.25e-196 citG 2.4.2.52 - H ko:K05966 ko02020,map02020 ko00000,ko00001,ko01000 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
NHMLFFNE_01083 1.78e-143 - - - I - - - Alpha/beta hydrolase family
NHMLFFNE_01084 1.34e-200 - - - K - - - LysR family
NHMLFFNE_01085 0.0 - - - S - - - Putative threonine/serine exporter
NHMLFFNE_01086 3.54e-148 - 3.2.2.27 - L ko:K21929 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Uracil-DNA glycosylase
NHMLFFNE_01087 1.63e-63 qacA - - EGP - - - Major Facilitator
NHMLFFNE_01088 4.56e-226 qacA - - EGP - - - Major Facilitator
NHMLFFNE_01089 1.03e-236 - - - I - - - Alpha beta
NHMLFFNE_01090 1.48e-129 - 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 DJ-1/PfpI family
NHMLFFNE_01091 0.0 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
NHMLFFNE_01092 9.09e-260 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
NHMLFFNE_01093 2.98e-152 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
NHMLFFNE_01094 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
NHMLFFNE_01095 0.0 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
NHMLFFNE_01096 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
NHMLFFNE_01097 0.0 sdrF - - M ko:K14194 ko05150,map05150 ko00000,ko00001 protein which possibly mediates interactions of S.aureus with components of the extracellular matrix of higher eukaryotes
NHMLFFNE_01098 0.0 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Poly(Glycerol-phosphate) alpha-glucosyltransferase
NHMLFFNE_01099 0.0 tagE6 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
NHMLFFNE_01100 8.2e-93 - - - - - - - -
NHMLFFNE_01101 6.31e-292 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
NHMLFFNE_01102 2.81e-230 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
NHMLFFNE_01103 1.79e-214 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
NHMLFFNE_01105 5.88e-121 - - - S - - - NADPH-dependent FMN reductase
NHMLFFNE_01106 0.0 - - - G ko:K03832 - ko00000,ko02000 Belongs to the glycosyl hydrolase family 6
NHMLFFNE_01107 3.45e-103 - - - S - - - Conserved hypothetical protein 698
NHMLFFNE_01108 2.65e-71 - - - S - - - Conserved hypothetical protein 698
NHMLFFNE_01109 9.77e-170 - - - I - - - alpha/beta hydrolase fold
NHMLFFNE_01110 1.08e-218 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
NHMLFFNE_01111 2.15e-144 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Peroxidase
NHMLFFNE_01112 1.12e-70 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Peroxidase
NHMLFFNE_01113 0.0 arcD - - S - - - C4-dicarboxylate anaerobic carrier
NHMLFFNE_01114 0.0 arcT - - E - - - Dipeptidase
NHMLFFNE_01115 6.82e-74 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NHMLFFNE_01116 7.1e-132 ypsA - - S - - - Belongs to the UPF0398 family
NHMLFFNE_01117 8.19e-152 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NHMLFFNE_01118 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
NHMLFFNE_01119 2.42e-208 - - - EG - - - EamA-like transporter family
NHMLFFNE_01120 5e-161 dnaD - - L ko:K02086 - ko00000 DnaD domain protein
NHMLFFNE_01121 9.09e-113 ypmB - - S - - - Protein conserved in bacteria
NHMLFFNE_01122 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
NHMLFFNE_01123 1.21e-218 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 mevalonate kinase
NHMLFFNE_01124 1.47e-218 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
NHMLFFNE_01125 9.67e-273 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
NHMLFFNE_01126 7.32e-247 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NHMLFFNE_01127 2.6e-116 - - - S ko:K08996 - ko00000 Protein of unknown function (DUF1440)
NHMLFFNE_01128 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
NHMLFFNE_01129 9.48e-184 - - - M - - - Leucine-rich repeat (LRR) protein
NHMLFFNE_01130 1.64e-44 - - - M - - - LPXTG-motif cell wall anchor domain protein
NHMLFFNE_01131 3.03e-11 - - - NU - - - Mycoplasma protein of unknown function, DUF285
NHMLFFNE_01133 4.16e-200 metQ1 - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
NHMLFFNE_01134 3.82e-114 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NHMLFFNE_01135 6.36e-161 - - - O - - - Zinc-dependent metalloprotease
NHMLFFNE_01136 5.11e-146 - - - S - - - Membrane
NHMLFFNE_01137 1.96e-253 - 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
NHMLFFNE_01138 3.65e-118 - - - S - - - Domain of unknown function (DUF4767)
NHMLFFNE_01139 3.7e-19 - - - - - - - -
NHMLFFNE_01140 3.09e-267 thiP - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
NHMLFFNE_01141 2.98e-273 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
NHMLFFNE_01142 7.87e-120 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
NHMLFFNE_01143 9.41e-146 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
NHMLFFNE_01144 2.53e-121 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
NHMLFFNE_01145 1.18e-224 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NHMLFFNE_01146 1.36e-233 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
NHMLFFNE_01147 4.45e-109 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NHMLFFNE_01148 1.8e-81 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
NHMLFFNE_01149 2.98e-216 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NHMLFFNE_01150 1.76e-188 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
NHMLFFNE_01151 3.56e-233 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
NHMLFFNE_01152 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
NHMLFFNE_01153 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NHMLFFNE_01154 5.12e-266 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NHMLFFNE_01155 1.09e-182 - - - E - - - AzlC protein
NHMLFFNE_01156 8.18e-70 - - - S - - - branched-chain amino acid
NHMLFFNE_01157 3.04e-181 - - - K - - - LysR substrate binding domain
NHMLFFNE_01158 3.9e-49 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
NHMLFFNE_01159 7.09e-153 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
NHMLFFNE_01160 1.01e-311 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NHMLFFNE_01161 3.93e-220 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NHMLFFNE_01162 8.92e-164 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NHMLFFNE_01163 2.5e-146 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NHMLFFNE_01164 9.09e-149 - - - S - - - Haloacid dehalogenase-like hydrolase
NHMLFFNE_01165 1.27e-292 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
NHMLFFNE_01166 1.76e-221 ydbI - - K - - - AI-2E family transporter
NHMLFFNE_01167 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
NHMLFFNE_01168 7.52e-121 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
NHMLFFNE_01169 9.68e-268 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
NHMLFFNE_01170 6.6e-168 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Belongs to the alpha-acetolactate decarboxylase family
NHMLFFNE_01171 6.05e-108 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NHMLFFNE_01172 1.44e-274 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NHMLFFNE_01173 0.0 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NHMLFFNE_01174 8.68e-169 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
NHMLFFNE_01175 1.84e-49 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NHMLFFNE_01176 2.7e-161 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NHMLFFNE_01177 4.13e-286 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NHMLFFNE_01178 2.14e-227 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NHMLFFNE_01179 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NHMLFFNE_01180 2.1e-245 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
NHMLFFNE_01181 1.05e-111 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NHMLFFNE_01182 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
NHMLFFNE_01183 1.45e-166 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NHMLFFNE_01184 8.97e-216 - - - - - - - -
NHMLFFNE_01185 4.52e-301 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NHMLFFNE_01186 2.3e-21 - - - - - - - -
NHMLFFNE_01187 4.16e-26 - - - S - - - Phage gp6-like head-tail connector protein
NHMLFFNE_01188 1.27e-202 - - - S ko:K06904 - ko00000 Caudovirus prohead serine protease
NHMLFFNE_01189 3.63e-62 - - - S ko:K06904 - ko00000 Caudovirus prohead serine protease
NHMLFFNE_01190 6.16e-179 - - - S - - - Phage portal protein
NHMLFFNE_01191 3.06e-252 terL - - S - - - overlaps another CDS with the same product name
NHMLFFNE_01192 8.22e-29 terS - - L - - - Phage terminase, small subunit
NHMLFFNE_01193 1.31e-39 - - - L - - - HNH endonuclease
NHMLFFNE_01196 2.86e-113 - - - S ko:K06919 - ko00000 Phage plasmid primase, P4
NHMLFFNE_01197 7.36e-47 - - - L - - - Bifunctional DNA primase/polymerase, N-terminal
NHMLFFNE_01201 8.97e-17 - - - S - - - Arc-like DNA binding domain
NHMLFFNE_01203 9.04e-07 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
NHMLFFNE_01204 9.86e-68 - - - L - - - Belongs to the 'phage' integrase family
NHMLFFNE_01205 4.21e-103 - - - S - - - Phage tail protein
NHMLFFNE_01206 3.01e-257 - - - D - - - Phage tail tape measure protein
NHMLFFNE_01208 7.66e-30 - - - S - - - Phage tail assembly chaperone protein, TAC
NHMLFFNE_01209 3.25e-54 - - - S - - - Phage tail tube protein
NHMLFFNE_01210 5.39e-39 - - - S - - - Protein of unknown function (DUF3168)
NHMLFFNE_01211 1.12e-41 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
NHMLFFNE_01212 1.31e-47 - - - - - - - -
NHMLFFNE_01213 2.31e-40 - - - S - - - Phage gp6-like head-tail connector protein
NHMLFFNE_01214 1.38e-158 - - - - - - - -
NHMLFFNE_01215 7.28e-59 - - - S - - - Domain of unknown function (DUF4355)
NHMLFFNE_01217 6.93e-86 - - - S - - - Phage Mu protein F like protein
NHMLFFNE_01218 5.39e-187 - - - S - - - Phage portal protein
NHMLFFNE_01219 2.06e-198 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
NHMLFFNE_01220 1.47e-245 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NHMLFFNE_01221 5.25e-140 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NHMLFFNE_01222 1.44e-277 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
NHMLFFNE_01223 0.0 eriC - - P ko:K03281 - ko00000 chloride
NHMLFFNE_01224 4.29e-101 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
NHMLFFNE_01225 3.48e-132 - - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, permease protein
NHMLFFNE_01226 2.13e-182 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NHMLFFNE_01227 1.11e-137 proWZ - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NHMLFFNE_01228 1.7e-205 proWY - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, QAT family
NHMLFFNE_01229 1.11e-96 ywnA - - K - - - Transcriptional regulator
NHMLFFNE_01230 1.05e-106 - - - GM - - - NAD(P)H-binding
NHMLFFNE_01231 2.57e-10 - - - - - - - -
NHMLFFNE_01232 5.23e-276 - 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Metalloenzyme superfamily
NHMLFFNE_01233 3.92e-219 cadA - - P - - - P-type ATPase
NHMLFFNE_01235 1.63e-07 - - - - - - - -
NHMLFFNE_01237 0.000192 - - - S - - - Domain of unknown function (DUF4767)
NHMLFFNE_01238 2.29e-188 - - - S - - - PD-(D/E)XK nuclease family transposase
NHMLFFNE_01240 0.0 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
NHMLFFNE_01241 5.26e-236 galR - - K ko:K02529 - ko00000,ko03000 Periplasmic binding protein-like domain
NHMLFFNE_01242 2.46e-215 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
NHMLFFNE_01243 1.22e-213 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
NHMLFFNE_01244 4.2e-159 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 LrgB-like family
NHMLFFNE_01245 3.69e-87 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 LrgA family
NHMLFFNE_01246 5.8e-166 lytT - - K ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator receiver
NHMLFFNE_01247 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 LytS YhcK-type transmembrane receptor domain protein
NHMLFFNE_01248 5.16e-190 - - - O - - - Band 7 protein
NHMLFFNE_01249 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
NHMLFFNE_01250 1.4e-199 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
NHMLFFNE_01251 9.36e-48 - - - S - - - Cytochrome B5
NHMLFFNE_01252 1.18e-49 - - - D - - - domain protein
NHMLFFNE_01255 9.74e-90 - - - K ko:K07741 - ko00000 AntA/AntB antirepressor
NHMLFFNE_01262 4.6e-50 - - - S - - - DNA binding
NHMLFFNE_01263 2.33e-14 - - - K - - - Helix-turn-helix XRE-family like proteins
NHMLFFNE_01264 1.77e-85 - - - K - - - Peptidase S24-like
NHMLFFNE_01265 9.32e-58 - - - M - - - Host cell surface-exposed lipoprotein
NHMLFFNE_01268 7.69e-20 - - - S - - - Domain of unknown function (DUF4393)
NHMLFFNE_01270 8.18e-94 - - - L - - - Belongs to the 'phage' integrase family
NHMLFFNE_01271 2.01e-153 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
NHMLFFNE_01272 1.18e-179 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NHMLFFNE_01273 5.96e-206 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NHMLFFNE_01274 1.33e-47 yozE - - S - - - Belongs to the UPF0346 family
NHMLFFNE_01275 1.36e-139 ypmS - - S - - - Uncharacterized protein conserved in bacteria (DUF2140)
NHMLFFNE_01276 7.94e-220 - - - E - - - lipolytic protein G-D-S-L family
NHMLFFNE_01277 2.13e-194 WQ51_01275 - - S - - - EDD domain protein, DegV family
NHMLFFNE_01278 5.6e-94 - - - K - - - Transcriptional regulator, TetR family
NHMLFFNE_01279 1.4e-160 - - - M - - - PFAM NLP P60 protein
NHMLFFNE_01280 3.53e-230 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
NHMLFFNE_01281 1.37e-195 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
NHMLFFNE_01282 1.61e-176 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NHMLFFNE_01283 9.12e-30 - - - P - - - Cadmium resistance transporter
NHMLFFNE_01284 1.14e-74 czrA - - K ko:K22043 - ko00000,ko03000 Transcriptional regulator, ArsR family
NHMLFFNE_01285 5.79e-83 - - - M - - - domain protein
NHMLFFNE_01286 6.26e-25 - - - M - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NHMLFFNE_01287 2.34e-58 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
NHMLFFNE_01288 1.02e-195 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
NHMLFFNE_01289 2.54e-71 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
NHMLFFNE_01290 1.08e-168 yceF - - P ko:K05794 - ko00000 membrane
NHMLFFNE_01291 6.71e-241 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NHMLFFNE_01292 1.81e-50 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
NHMLFFNE_01293 6.12e-166 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NHMLFFNE_01294 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
NHMLFFNE_01295 3.71e-268 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NHMLFFNE_01296 4.23e-76 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NHMLFFNE_01297 0.0 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NHMLFFNE_01298 1.21e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
NHMLFFNE_01299 1.47e-50 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
NHMLFFNE_01300 4.38e-118 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NHMLFFNE_01301 5.46e-183 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
NHMLFFNE_01302 6.03e-134 - - - E ko:K03294 - ko00000 amino acid
NHMLFFNE_01303 1.08e-138 - - - E ko:K03294 - ko00000 amino acid
NHMLFFNE_01304 3.03e-83 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NHMLFFNE_01305 4.43e-152 csrR - - K - - - response regulator
NHMLFFNE_01306 0.0 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NHMLFFNE_01307 0.0 potE - - E - - - Amino Acid
NHMLFFNE_01308 1.55e-250 - - - V - - - MatE
NHMLFFNE_01309 1.22e-12 - - - V - - - MatE
NHMLFFNE_01310 1.11e-91 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
NHMLFFNE_01311 3.89e-215 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NHMLFFNE_01312 3.48e-58 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
NHMLFFNE_01313 6.64e-187 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NHMLFFNE_01314 3.75e-119 XK27_09705 - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
NHMLFFNE_01315 5.79e-78 yodB - - K - - - Transcriptional regulator, HxlR family
NHMLFFNE_01316 4.27e-251 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NHMLFFNE_01317 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NHMLFFNE_01319 5.82e-111 XK27_05190 - - S - - - Protein of unknown function (DUF1694)
NHMLFFNE_01320 1.61e-310 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
NHMLFFNE_01321 3.61e-61 - - - - - - - -
NHMLFFNE_01322 1.95e-109 uspA - - T - - - universal stress protein
NHMLFFNE_01323 1.3e-265 araR - - K ko:K02103 - ko00000,ko03000 Transcriptional regulator
NHMLFFNE_01324 1.03e-201 yvgN - - S - - - Aldo keto reductase
NHMLFFNE_01325 1.54e-135 maa 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
NHMLFFNE_01326 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
NHMLFFNE_01327 4.71e-28 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
NHMLFFNE_01328 6.75e-126 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
NHMLFFNE_01329 0.0 araB 2.7.1.16 - G ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 carbohydrate kinase FGGY
NHMLFFNE_01330 2.72e-212 araP - - U - - - Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NHMLFFNE_01331 4.19e-104 araP - - U - - - Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NHMLFFNE_01332 2.58e-191 - - - K - - - Helix-turn-helix XRE-family like proteins
NHMLFFNE_01333 4.24e-214 - - - C - - - Aldo keto reductase
NHMLFFNE_01334 9.31e-63 - - - S - - - Cupin 2, conserved barrel domain protein
NHMLFFNE_01335 0.0 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Membrane domain of glycerophosphoryl diester phosphodiesterase
NHMLFFNE_01336 9.24e-114 - - - S - - - ECF-type riboflavin transporter, S component
NHMLFFNE_01337 0.0 nox 1.6.3.4 - C ko:K17869 - ko00000,ko01000 NADH oxidase
NHMLFFNE_01338 1.15e-119 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NHMLFFNE_01339 3.19e-106 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NHMLFFNE_01340 9.58e-159 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NHMLFFNE_01341 4.41e-78 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NHMLFFNE_01342 6.87e-52 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NHMLFFNE_01343 6.29e-129 - - - - - - - -
NHMLFFNE_01344 1.1e-121 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NHMLFFNE_01346 1.05e-86 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
NHMLFFNE_01347 5.46e-315 - - - E - - - amino acid
NHMLFFNE_01348 4.45e-275 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
NHMLFFNE_01349 1.42e-62 gcsH2 - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 glycine cleavage
NHMLFFNE_01350 2.72e-281 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
NHMLFFNE_01351 1.88e-43 - - - S - - - Protein of unknown function (DUF2969)
NHMLFFNE_01352 1.27e-54 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
NHMLFFNE_01353 1.05e-226 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
NHMLFFNE_01354 6.32e-310 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NHMLFFNE_01355 1.76e-45 ywzB - - S - - - Protein of unknown function (DUF1146)
NHMLFFNE_01356 2.57e-89 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
NHMLFFNE_01357 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NHMLFFNE_01358 3.72e-212 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NHMLFFNE_01359 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NHMLFFNE_01360 6.84e-121 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NHMLFFNE_01361 8.82e-95 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NHMLFFNE_01362 1.26e-29 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NHMLFFNE_01363 4.63e-162 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
NHMLFFNE_01364 9.76e-295 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
NHMLFFNE_01365 1.64e-166 yibF - - S - - - overlaps another CDS with the same product name
NHMLFFNE_01366 1.16e-246 yibE - - S - - - overlaps another CDS with the same product name
NHMLFFNE_01367 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NHMLFFNE_01368 7.8e-149 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NHMLFFNE_01369 8.26e-290 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NHMLFFNE_01370 1.88e-251 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NHMLFFNE_01371 8.55e-214 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NHMLFFNE_01372 1.73e-248 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NHMLFFNE_01373 6.8e-140 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
NHMLFFNE_01374 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Mur ligase, middle domain
NHMLFFNE_01375 4.87e-173 - - - S ko:K07009 - ko00000 CobB/CobQ-like glutamine amidotransferase domain
NHMLFFNE_01376 6.57e-296 potE - - U ko:K03756,ko:K03758 - ko00000,ko02000 Amino acid permease
NHMLFFNE_01377 0.0 arcD - - E ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
NHMLFFNE_01378 8.76e-104 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
NHMLFFNE_01379 2.42e-302 arcA 3.5.3.6 - E ko:K01478 ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130 ko00000,ko00001,ko01000 Arginine
NHMLFFNE_01380 8.22e-269 atoB 1.1.1.88, 2.3.1.9 - I ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
NHMLFFNE_01381 3.16e-207 malR1 - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
NHMLFFNE_01382 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
NHMLFFNE_01383 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
NHMLFFNE_01384 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NHMLFFNE_01385 1.35e-127 - - - K - - - PFAM GCN5-related N-acetyltransferase
NHMLFFNE_01394 1.19e-74 - - - S - - - Protein of unknown function (DUF3102)
NHMLFFNE_01395 2.11e-28 - - - - - - - -
NHMLFFNE_01398 7.12e-65 - - - K ko:K07727 - ko00000,ko03000 addiction module antidote protein HigA
NHMLFFNE_01399 4.57e-97 - - - E - - - IrrE N-terminal-like domain
NHMLFFNE_01401 1.72e-73 - - - L - - - Phage integrase family
NHMLFFNE_01402 3.87e-200 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
NHMLFFNE_01403 6.57e-224 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NHMLFFNE_01404 8.35e-315 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NHMLFFNE_01405 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NHMLFFNE_01406 8.21e-19 - - - - - - - -
NHMLFFNE_01407 1.2e-50 - - - M - - - Sortase family
NHMLFFNE_01408 7.78e-28 nrdI - - F ko:K03647 - ko00000 NrdI Flavodoxin like
NHMLFFNE_01411 1.53e-60 - - - - - - - -
NHMLFFNE_01412 2.05e-131 - - - K - - - Helix-turn-helix domain
NHMLFFNE_01413 0.0 - - - S - - - ABC transporter, ATP-binding protein
NHMLFFNE_01414 5.9e-186 - - - S - - - Putative ABC-transporter type IV
NHMLFFNE_01415 1.16e-134 - - - NU - - - mannosyl-glycoprotein
NHMLFFNE_01416 1.24e-314 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
NHMLFFNE_01417 1.1e-294 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
NHMLFFNE_01418 3.57e-260 yngD - - S ko:K07097 - ko00000 DHHA1 domain
NHMLFFNE_01419 4.28e-40 - 3.4.11.5 - I ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
NHMLFFNE_01420 5.45e-76 - 3.4.11.5 - I ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
NHMLFFNE_01421 2.09e-116 - - - E ko:K03294 - ko00000 Amino acid permease
NHMLFFNE_01422 2.7e-56 - - - E ko:K03294 - ko00000 amino acid
NHMLFFNE_01423 2.04e-65 - - - - - - - -
NHMLFFNE_01424 9.83e-163 - - - S - - - PD-(D/E)XK nuclease family transposase
NHMLFFNE_01426 3.32e-72 - - - - - - - -
NHMLFFNE_01427 2.65e-148 yrkL - - S - - - Flavodoxin-like fold
NHMLFFNE_01430 1.92e-86 yeaO - - S - - - Protein of unknown function, DUF488
NHMLFFNE_01431 2.73e-153 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
NHMLFFNE_01432 2.07e-261 - - - S - - - associated with various cellular activities
NHMLFFNE_01433 5.37e-307 - - - S - - - Putative metallopeptidase domain
NHMLFFNE_01434 1.21e-63 - - - - - - - -
NHMLFFNE_01435 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
NHMLFFNE_01436 5.03e-111 - - - S - - - Short repeat of unknown function (DUF308)
NHMLFFNE_01437 7.03e-33 - - - - - - - -
NHMLFFNE_01438 5.6e-133 - - - V - - - VanZ like family
NHMLFFNE_01439 4.05e-302 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
NHMLFFNE_01440 1.46e-110 perR - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
NHMLFFNE_01441 0.0 - - - EGP - - - Major Facilitator
NHMLFFNE_01442 5.22e-120 tag1 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
NHMLFFNE_01443 7.77e-280 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NHMLFFNE_01444 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
NHMLFFNE_01445 2.42e-54 - - - - - - - -
NHMLFFNE_01446 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
NHMLFFNE_01447 0.0 yhdG - - E ko:K03294 - ko00000 Amino Acid
NHMLFFNE_01448 1.07e-288 - - - EGP ko:K08368 - ko00000,ko02000 Sugar (and other) transporter
NHMLFFNE_01449 2.05e-295 - - - - - - - -
NHMLFFNE_01450 4.91e-266 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NHMLFFNE_01451 1.54e-183 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NHMLFFNE_01452 2.49e-187 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NHMLFFNE_01453 8.43e-261 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NHMLFFNE_01454 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
NHMLFFNE_01455 2.13e-226 - 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
NHMLFFNE_01456 7.2e-209 - - - I - - - alpha/beta hydrolase fold
NHMLFFNE_01457 2.6e-27 - - - K - - - Helix-turn-helix XRE-family like proteins
NHMLFFNE_01459 4.77e-65 yrvD - - S - - - Pfam:DUF1049
NHMLFFNE_01460 9.28e-191 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
NHMLFFNE_01461 1.38e-117 ntd 2.4.2.6 - F ko:K08728 ko00240,map00240 ko00000,ko00001,ko01000 Nucleoside
NHMLFFNE_01462 4.85e-27 - - - - - - - -
NHMLFFNE_01463 1.86e-212 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
NHMLFFNE_01464 3.62e-78 - - - S - - - Protein of unknown function (DUF421)
NHMLFFNE_01465 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 Putative exonuclease SbcCD, C subunit
NHMLFFNE_01466 2.86e-268 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NHMLFFNE_01467 4.54e-227 - - - M - - - Glycosyl hydrolases family 25
NHMLFFNE_01468 1.14e-182 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
NHMLFFNE_01469 3.91e-168 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
NHMLFFNE_01470 1.61e-178 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 alpha subunit
NHMLFFNE_01471 5.67e-182 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NHMLFFNE_01472 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
NHMLFFNE_01473 5.61e-98 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NHMLFFNE_01474 5.1e-97 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NHMLFFNE_01475 4.72e-284 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NHMLFFNE_01476 1.17e-164 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
NHMLFFNE_01477 1.92e-194 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
NHMLFFNE_01478 1.46e-46 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
NHMLFFNE_01479 4.44e-225 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NHMLFFNE_01480 1.79e-96 - - - K - - - Transcriptional regulator, MarR family
NHMLFFNE_01481 1.76e-94 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NHMLFFNE_01483 8.4e-259 xerS - - L - - - Belongs to the 'phage' integrase family
NHMLFFNE_01486 9.4e-68 - - - - - - - -
NHMLFFNE_01488 2.13e-55 - - - K - - - Helix-turn-helix XRE-family like proteins
NHMLFFNE_01489 4.63e-12 - - - - - - - -
NHMLFFNE_01491 8.58e-85 - - - S - - - DNA binding
NHMLFFNE_01494 9.09e-20 - - - S ko:K09946 - ko00000 Domain of unknown function (DUF1508)
NHMLFFNE_01495 0.000472 - - - K - - - Helix-turn-helix XRE-family like proteins
NHMLFFNE_01500 8.35e-146 - - - S - - - AAA domain
NHMLFFNE_01501 1.11e-84 - - - S - - - Protein of unknown function (DUF669)
NHMLFFNE_01502 1.29e-162 - - - L - - - Psort location Cytoplasmic, score
NHMLFFNE_01506 1.1e-46 - - - S - - - ORF6C domain
NHMLFFNE_01507 7.16e-13 - - - - - - - -
NHMLFFNE_01510 3.01e-257 - - - D - - - Phage tail tape measure protein
NHMLFFNE_01512 7.66e-30 - - - S - - - Phage tail assembly chaperone protein, TAC
NHMLFFNE_01513 3.25e-54 - - - S - - - Phage tail tube protein
NHMLFFNE_01514 5.39e-39 - - - S - - - Protein of unknown function (DUF3168)
NHMLFFNE_01515 1.12e-41 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
NHMLFFNE_01516 1.31e-47 - - - - - - - -
NHMLFFNE_01517 2.31e-40 - - - S - - - Phage gp6-like head-tail connector protein
NHMLFFNE_01518 1.38e-158 - - - - - - - -
NHMLFFNE_01519 7.28e-59 - - - S - - - Domain of unknown function (DUF4355)
NHMLFFNE_01521 6.93e-86 - - - S - - - Phage Mu protein F like protein
NHMLFFNE_01522 5.39e-187 - - - S - - - Phage portal protein
NHMLFFNE_01523 4.29e-70 - - - S - - - Mazg nucleotide pyrophosphohydrolase
NHMLFFNE_01524 2.53e-204 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
NHMLFFNE_01525 4.52e-83 - - - - - - - -
NHMLFFNE_01526 4.09e-15 - - - - - - - -
NHMLFFNE_01527 7.8e-238 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
NHMLFFNE_01528 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
NHMLFFNE_01529 0.0 lacZ 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 -beta-galactosidase
NHMLFFNE_01530 2.68e-227 hepT 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
NHMLFFNE_01531 8.07e-204 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
NHMLFFNE_01532 3.54e-165 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
NHMLFFNE_01533 4.25e-290 mdtG2 - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
NHMLFFNE_01534 2.36e-104 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NHMLFFNE_01535 2.61e-260 - - - - - - - -
NHMLFFNE_01536 1.76e-68 - - - - - - - -
NHMLFFNE_01537 1.21e-48 - - - - - - - -
NHMLFFNE_01538 1.86e-119 - - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
NHMLFFNE_01539 1.34e-187 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
NHMLFFNE_01540 3.03e-231 celE3 - - E - - - GDSL-like Lipase/Acylhydrolase family
NHMLFFNE_01541 1.16e-284 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NHMLFFNE_01542 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
NHMLFFNE_01543 3.98e-231 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
NHMLFFNE_01544 5.16e-133 apl 3.1.3.1 - S ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 SNARE associated Golgi protein
NHMLFFNE_01545 2.49e-295 gltT - - U ko:K03309,ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NHMLFFNE_01546 1.81e-28 - - - K ko:K03719 - ko00000,ko03000,ko03036 AsnC family
NHMLFFNE_01547 4.44e-91 - - - - - - - -
NHMLFFNE_01548 1.43e-73 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NHMLFFNE_01549 4.47e-23 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
NHMLFFNE_01550 2.09e-86 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
NHMLFFNE_01551 1.17e-136 folE 2.7.6.3, 3.5.4.16 - F ko:K00950,ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase 1
NHMLFFNE_01552 3.1e-31 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
NHMLFFNE_01553 7.83e-116 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
NHMLFFNE_01554 6.71e-78 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
NHMLFFNE_01555 1.36e-132 folQ 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Ham1 family
NHMLFFNE_01556 7.39e-274 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 dihydropteroate synthase
NHMLFFNE_01557 4.61e-61 - - - - - - - -
NHMLFFNE_01558 3.16e-44 - - - - - - - -
NHMLFFNE_01560 1.3e-211 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
NHMLFFNE_01561 8.74e-194 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
NHMLFFNE_01562 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
NHMLFFNE_01563 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
NHMLFFNE_01564 2.42e-64 yheA - - S - - - Belongs to the UPF0342 family
NHMLFFNE_01565 1.97e-277 yhaO - - L ko:K03547 - ko00000,ko03400 Ser Thr phosphatase family protein
NHMLFFNE_01566 0.0 yhaN - - L - - - AAA domain
NHMLFFNE_01567 5.63e-178 prsA 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NHMLFFNE_01569 1.49e-102 hit - - FG ko:K02503 - ko00000,ko04147 histidine triad
NHMLFFNE_01570 5.44e-175 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NHMLFFNE_01571 6.36e-277 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
NHMLFFNE_01572 5.3e-157 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NHMLFFNE_01573 7.47e-60 - 2.1.1.72, 3.1.21.3 AA10,CBM73 M ko:K01154,ko:K02014,ko:K03933,ko:K07316 - ko00000,ko01000,ko02000,ko02048 domain protein
NHMLFFNE_01574 6.17e-191 - 2.1.1.72, 3.1.21.3 AA10,CBM73 M ko:K01154,ko:K02014,ko:K03933,ko:K07316 - ko00000,ko01000,ko02000,ko02048 domain protein
NHMLFFNE_01575 6.87e-181 - - - D - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NHMLFFNE_01576 1.84e-270 tagE3 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
NHMLFFNE_01577 5.38e-49 tagE3 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
NHMLFFNE_01578 2.19e-155 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
NHMLFFNE_01579 5.17e-45 - - - S - - - PFAM Archaeal ATPase
NHMLFFNE_01580 1.35e-202 - - - J - - - Methyltransferase
NHMLFFNE_01581 7.74e-279 oxlT - - P ko:K08177 - ko00000,ko02000 Major Facilitator Superfamily
NHMLFFNE_01582 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
NHMLFFNE_01585 6.9e-279 - - - S ko:K07133 - ko00000 cog cog1373
NHMLFFNE_01586 5.86e-226 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
NHMLFFNE_01587 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NHMLFFNE_01588 1.64e-203 - - - EG - - - EamA-like transporter family
NHMLFFNE_01589 6.76e-08 - - - - - - - -
NHMLFFNE_01590 1.78e-83 - - - - - - - -
NHMLFFNE_01591 9.23e-245 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
NHMLFFNE_01592 2.5e-104 uspA3 - - T - - - universal stress protein
NHMLFFNE_01593 8.87e-204 fusA1 - - J - - - elongation factor G
NHMLFFNE_01594 7.94e-42 - - - S - - - Protein of unknown function (DUF2929)
NHMLFFNE_01595 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
NHMLFFNE_01596 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
NHMLFFNE_01597 7.61e-215 yitL - - S ko:K00243 - ko00000 S1 domain
NHMLFFNE_01598 2.01e-212 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
NHMLFFNE_01599 4.29e-85 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NHMLFFNE_01600 2.77e-177 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NHMLFFNE_01601 2.24e-134 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NHMLFFNE_01602 1.43e-164 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
NHMLFFNE_01603 2.65e-133 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NHMLFFNE_01604 5.69e-62 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NHMLFFNE_01605 1.8e-72 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NHMLFFNE_01606 4.43e-300 uvrA2 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 excinuclease ABC, A subunit
NHMLFFNE_01607 2.03e-166 uvrA2 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 excinuclease ABC, A subunit
NHMLFFNE_01608 9.31e-155 - - - S - - - SNARE associated Golgi protein
NHMLFFNE_01609 3.75e-79 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
NHMLFFNE_01610 1.79e-163 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
NHMLFFNE_01611 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NHMLFFNE_01613 0.0 yifK - - E ko:K03293 - ko00000 Amino acid permease
NHMLFFNE_01614 3.3e-200 endA - - V ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
NHMLFFNE_01615 3.6e-158 radC - - L ko:K03630 - ko00000 DNA repair protein
NHMLFFNE_01616 8.33e-230 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
NHMLFFNE_01617 7.72e-195 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
NHMLFFNE_01618 1.69e-120 mreD - - M ko:K03571 - ko00000,ko03036 rod shape-determining protein MreD
NHMLFFNE_01619 1.81e-140 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
NHMLFFNE_01620 8.39e-151 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NHMLFFNE_01621 1.64e-204 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
NHMLFFNE_01622 8.66e-294 ymfF - - S - - - Peptidase M16 inactive domain protein
NHMLFFNE_01623 3.66e-315 ymfH - - S - - - Peptidase M16
NHMLFFNE_01624 6.06e-194 - - - S - - - Helix-turn-helix domain
NHMLFFNE_01625 1.93e-132 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NHMLFFNE_01626 0.0 - - - L - - - PLD-like domain
NHMLFFNE_01628 2.19e-77 rihA - - F ko:K01250 - ko00000,ko01000 Inosine-uridine preferring nucleoside hydrolase
NHMLFFNE_01629 5.06e-69 rihA - - F ko:K01250 - ko00000,ko01000 Inosine-uridine preferring nucleoside hydrolase
NHMLFFNE_01630 3.18e-226 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NHMLFFNE_01631 1.04e-118 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
NHMLFFNE_01632 1.49e-277 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
NHMLFFNE_01633 1.3e-100 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
NHMLFFNE_01634 8.24e-143 - - - T ko:K10716 - ko00000,ko02000 Ion transport 2 domain protein
NHMLFFNE_01635 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
NHMLFFNE_01636 3.39e-90 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NHMLFFNE_01637 9.38e-189 - - - S - - - DUF218 domain
NHMLFFNE_01638 0.0 ubiB - - S ko:K03688 - ko00000 ABC1 family
NHMLFFNE_01639 1.68e-303 yhdP - - S - - - Transporter associated domain
NHMLFFNE_01640 9.74e-98 atkY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor CopY TcrY
NHMLFFNE_01641 5.84e-309 - - - U - - - Belongs to the major facilitator superfamily
NHMLFFNE_01642 1.58e-96 - - - S - - - UPF0756 membrane protein
NHMLFFNE_01643 1.76e-105 - - - S - - - Cupin domain
NHMLFFNE_01644 8.01e-107 - - - C - - - Flavodoxin
NHMLFFNE_01645 1.88e-57 rlrB - - K - - - LysR substrate binding domain protein
NHMLFFNE_01646 3.18e-81 rlrB - - K - - - LysR substrate binding domain protein
NHMLFFNE_01647 7.05e-217 yvgN - - C - - - Aldo keto reductase
NHMLFFNE_01648 0.0 malT - - G ko:K16211 - ko00000,ko02000 Major Facilitator
NHMLFFNE_01649 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
NHMLFFNE_01650 5.04e-154 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
NHMLFFNE_01651 5.05e-112 - - - T - - - Region found in RelA / SpoT proteins
NHMLFFNE_01652 2.29e-146 dltr - - K - - - response regulator
NHMLFFNE_01653 5.01e-274 sptS - - T - - - Histidine kinase
NHMLFFNE_01654 2.33e-108 - - - P - - - Voltage gated chloride channel
NHMLFFNE_01655 0.0 gshAB 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
NHMLFFNE_01656 1.69e-172 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
NHMLFFNE_01657 1.26e-98 - - - S - - - Psort location Cytoplasmic, score
NHMLFFNE_01658 0.0 umuC - - L ko:K03502 - ko00000,ko03400 impB/mucB/samB family C-terminal domain
NHMLFFNE_01659 3.81e-100 hsp - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
NHMLFFNE_01660 1.83e-196 yeaE - - S - - - Aldo keto
NHMLFFNE_01661 9.22e-306 - 1.3.1.1 - C ko:K17723 ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100 ko00000,ko00001,ko00002,ko01000 4Fe-4S dicluster domain
NHMLFFNE_01662 1.98e-298 - 1.3.1.1 - E ko:K17722 ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
NHMLFFNE_01663 2.83e-190 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
NHMLFFNE_01664 5e-141 - - - M - - - LysM domain protein
NHMLFFNE_01665 0.0 - - - EP - - - Psort location Cytoplasmic, score
NHMLFFNE_01666 6.95e-110 yslB - - S - - - Protein of unknown function (DUF2507)
NHMLFFNE_01667 4.46e-185 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
NHMLFFNE_01668 1.69e-67 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NHMLFFNE_01669 8.76e-121 - - - S ko:K07095 - ko00000 Phosphoesterase
NHMLFFNE_01670 6.01e-99 ykuL - - S - - - (CBS) domain
NHMLFFNE_01671 2.23e-195 - - - S - - - haloacid dehalogenase-like hydrolase
NHMLFFNE_01672 6.23e-188 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
NHMLFFNE_01673 6.26e-71 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NHMLFFNE_01674 4.51e-76 - - - - - - - -
NHMLFFNE_01675 5.75e-268 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
NHMLFFNE_01676 2.7e-232 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
NHMLFFNE_01677 8.47e-181 - - - - - - - -
NHMLFFNE_01678 3.5e-168 yebC - - K - - - Transcriptional regulatory protein
NHMLFFNE_01679 8.94e-229 - 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NHMLFFNE_01680 6.08e-13 - - - S - - - CsbD-like
NHMLFFNE_01681 9.4e-48 - - - S - - - Transglycosylase associated protein
NHMLFFNE_01682 3.98e-295 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NHMLFFNE_01683 1.58e-160 pgm3 - - G - - - phosphoglycerate mutase
NHMLFFNE_01684 1.34e-147 - - - S ko:K03975 - ko00000 SNARE associated Golgi protein
NHMLFFNE_01685 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
NHMLFFNE_01686 9.4e-312 nox 1.6.3.4 - C ko:K17869 - ko00000,ko01000 NADH oxidase
NHMLFFNE_01687 1.05e-278 nox 1.6.3.4 - C ko:K17869 - ko00000,ko01000 NADH oxidase
NHMLFFNE_01688 5.29e-71 - - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NHMLFFNE_01689 1.29e-58 - - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NHMLFFNE_01690 2.86e-34 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
NHMLFFNE_01691 4.17e-201 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
NHMLFFNE_01692 9.21e-143 - - - J - - - 2'-5' RNA ligase superfamily
NHMLFFNE_01693 2.27e-93 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
NHMLFFNE_01694 7.49e-91 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NHMLFFNE_01695 4.43e-190 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NHMLFFNE_01696 1.8e-307 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NHMLFFNE_01697 4.02e-58 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NHMLFFNE_01698 1.91e-202 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
NHMLFFNE_01699 1.62e-190 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
NHMLFFNE_01700 1.3e-99 argR2 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
NHMLFFNE_01701 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
NHMLFFNE_01702 9e-72 - - - - - - - -
NHMLFFNE_01703 4.37e-148 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
NHMLFFNE_01704 6.66e-43 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NHMLFFNE_01705 7.04e-270 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NHMLFFNE_01706 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NHMLFFNE_01707 1.22e-223 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NHMLFFNE_01708 1.66e-41 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NHMLFFNE_01709 3.23e-124 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NHMLFFNE_01710 1.05e-168 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
NHMLFFNE_01711 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
NHMLFFNE_01712 1.64e-206 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NHMLFFNE_01713 1.5e-149 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
NHMLFFNE_01714 1.91e-156 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
NHMLFFNE_01715 1.1e-34 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
NHMLFFNE_01716 1.05e-77 yloU - - S - - - Asp23 family, cell envelope-related function
NHMLFFNE_01717 0.0 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
NHMLFFNE_01718 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NHMLFFNE_01721 9.58e-303 yeeA - - V - - - Type II restriction enzyme, methylase subunits
NHMLFFNE_01722 5.39e-228 mprF - - I ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NHMLFFNE_01723 7.98e-253 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
NHMLFFNE_01724 1.88e-292 pimB 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
NHMLFFNE_01725 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NHMLFFNE_01726 3.69e-54 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
NHMLFFNE_01727 1.38e-37 - - - - - - - -
NHMLFFNE_01728 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
NHMLFFNE_01729 2.22e-130 - - - S - - - Pfam:DUF3816
NHMLFFNE_01730 9.48e-183 - - - G - - - MucBP domain
NHMLFFNE_01731 3.54e-201 yifK - - E ko:K03293 - ko00000 Amino acid permease
NHMLFFNE_01732 2.28e-95 yifK - - E ko:K03293 - ko00000 Amino acid permease
NHMLFFNE_01733 0.0 eriC - - P ko:K03281 - ko00000 chloride
NHMLFFNE_01734 1.43e-47 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
NHMLFFNE_01735 4.68e-187 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Serine aminopeptidase, S33
NHMLFFNE_01736 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NHMLFFNE_01737 7.73e-109 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NHMLFFNE_01738 2.26e-135 - - - - - - - -
NHMLFFNE_01739 1.84e-174 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NHMLFFNE_01740 3.97e-228 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
NHMLFFNE_01741 2.24e-302 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
NHMLFFNE_01742 3.49e-113 - - - - - - - -
NHMLFFNE_01743 7.14e-141 nnrE 5.1.99.6 - H ko:K17759 - ko00000,ko01000 Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
NHMLFFNE_01744 7.73e-39 - - - S - - - Putative peptidoglycan binding domain
NHMLFFNE_01745 1.54e-91 - - - S - - - Putative peptidoglycan binding domain
NHMLFFNE_01746 8.44e-161 - - - M - - - ErfK YbiS YcfS YnhG
NHMLFFNE_01748 1.4e-124 - - - - - - - -
NHMLFFNE_01749 1.39e-277 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
NHMLFFNE_01750 1.21e-186 - - - S - - - Alpha beta hydrolase
NHMLFFNE_01751 5.74e-264 gldA 1.1.1.6 - C ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 ko00000,ko00001,ko01000 dehydrogenase
NHMLFFNE_01752 3.13e-128 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NHMLFFNE_01753 1.96e-146 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Peptidase, S54 family
NHMLFFNE_01754 1.43e-47 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
NHMLFFNE_01755 2.93e-234 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
NHMLFFNE_01756 7.66e-88 yqhL - - P - - - Rhodanese-like protein
NHMLFFNE_01757 1.18e-30 - - - S - - - Protein of unknown function (DUF3042)
NHMLFFNE_01758 3.03e-219 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NHMLFFNE_01759 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
NHMLFFNE_01760 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NHMLFFNE_01761 3.44e-282 araT 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
NHMLFFNE_01762 5.24e-18 - - - - - - - -
NHMLFFNE_01763 4.34e-93 - - - Q - - - Methyltransferase
NHMLFFNE_01764 2.8e-152 ktrA - - P ko:K03499 - ko00000,ko02000 domain protein
NHMLFFNE_01765 3.91e-304 ktrB - - P ko:K03498 - ko00000,ko02000 Potassium uptake protein
NHMLFFNE_01766 0.0 mycA 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
NHMLFFNE_01767 6.61e-180 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
NHMLFFNE_01768 6.11e-278 - - - G - - - Glycosyl hydrolases family 8
NHMLFFNE_01769 8.29e-309 - - - M - - - Glycosyl transferase
NHMLFFNE_01770 3.83e-196 - - - - - - - -
NHMLFFNE_01771 9.75e-54 - - - S - - - Domain of unknown function DUF1829
NHMLFFNE_01772 3.46e-130 int3 - - L - - - Belongs to the 'phage' integrase family
NHMLFFNE_01774 9.17e-59 - - - - - - - -
NHMLFFNE_01775 2.02e-149 XK27_07085 - - S ko:K07052 - ko00000 CAAX protease self-immunity
NHMLFFNE_01776 2.09e-41 - - - - - - - -
NHMLFFNE_01777 1.1e-205 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NHMLFFNE_01778 1.98e-235 rbsR - - K ko:K02529 - ko00000,ko03000 Periplasmic binding proteins and sugar binding domain of LacI family
NHMLFFNE_01779 1.53e-146 - - - - - - - -
NHMLFFNE_01780 8.78e-150 dgk2 - - F - - - deoxynucleoside kinase
NHMLFFNE_01781 7.8e-225 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NHMLFFNE_01782 8.3e-160 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
NHMLFFNE_01783 6.35e-177 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NHMLFFNE_01784 7.4e-197 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
NHMLFFNE_01785 3.23e-194 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
NHMLFFNE_01786 1.15e-203 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
NHMLFFNE_01787 2.4e-169 - - - K ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C-terminal domain protein
NHMLFFNE_01788 1.9e-173 - - - P ko:K02006 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NHMLFFNE_01789 4.53e-181 - - - P ko:K02008 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
NHMLFFNE_01790 6.13e-234 cbiM - - P ko:K02007 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PDGLE domain
NHMLFFNE_01791 2.15e-46 - - - U - - - Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NHMLFFNE_01792 2e-56 - - - U - - - Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NHMLFFNE_01793 7.94e-34 ureD - - O ko:K03190 - ko00000 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
NHMLFFNE_01794 1.04e-190 mleR - - K - - - LysR family
NHMLFFNE_01795 1.64e-205 mleS 1.1.1.38, 4.1.1.101 - C ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme
NHMLFFNE_01796 4.96e-145 mleS 1.1.1.38, 4.1.1.101 - C ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme
NHMLFFNE_01797 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NHMLFFNE_01798 0.0 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
NHMLFFNE_01799 6.31e-168 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
NHMLFFNE_01800 7.5e-217 citP - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
NHMLFFNE_01801 6.73e-97 - 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase
NHMLFFNE_01802 1.69e-179 - - - S - - - Membrane
NHMLFFNE_01803 3.83e-177 - - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
NHMLFFNE_01804 4.86e-240 spxB 1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8 - EH ko:K00156,ko:K00158,ko:K01577,ko:K01652 ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
NHMLFFNE_01805 4.88e-115 spxB 1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8 - EH ko:K00156,ko:K00158,ko:K01577,ko:K01652 ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
NHMLFFNE_01806 0.0 frc 2.8.3.16 - C ko:K07749 - ko00000,ko01000 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
NHMLFFNE_01807 2.64e-302 pbuG - - S ko:K06901 - ko00000,ko02000 permease
NHMLFFNE_01808 1.04e-307 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphatidylserine decarboxylase family
NHMLFFNE_01809 1.12e-211 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
NHMLFFNE_01810 2.48e-57 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NHMLFFNE_01812 3.55e-154 sdhB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
NHMLFFNE_01813 1.11e-68 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
NHMLFFNE_01814 1.48e-102 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
NHMLFFNE_01815 3.25e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Peroxiredoxin
NHMLFFNE_01816 0.0 - 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Thioredoxin domain
NHMLFFNE_01817 5.44e-123 - - - M - - - LPXTG-motif cell wall anchor domain protein
NHMLFFNE_01818 1.23e-169 - - - M - - - LPXTG-motif cell wall anchor domain protein
NHMLFFNE_01819 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
NHMLFFNE_01820 1.39e-265 - - - M - - - LPXTG-motif cell wall anchor domain protein
NHMLFFNE_01823 4.85e-23 - - - UW - - - Tetratricopeptide repeat
NHMLFFNE_01824 0.0 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
NHMLFFNE_01825 9.64e-87 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
NHMLFFNE_01826 4.91e-289 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
NHMLFFNE_01827 1.1e-34 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
NHMLFFNE_01828 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NHMLFFNE_01829 2.35e-117 - - - - - - - -
NHMLFFNE_01830 6.59e-48 - - - - - - - -
NHMLFFNE_01831 2.02e-132 - - - K - - - DNA-templated transcription, initiation
NHMLFFNE_01832 3.8e-37 - - - - - - - -
NHMLFFNE_01833 7.71e-227 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NHMLFFNE_01834 2.15e-267 - 1.5.1.36 - S ko:K19784,ko:K22393,ko:K22394 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 reductase
NHMLFFNE_01835 2.66e-132 - 1.5.1.36 - S ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 reductase
NHMLFFNE_01836 3.31e-175 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NHMLFFNE_01837 8.25e-144 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NHMLFFNE_01838 5.04e-214 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
NHMLFFNE_01839 0.0 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NHMLFFNE_01840 1e-47 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NHMLFFNE_01841 9.07e-300 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
NHMLFFNE_01842 0.0 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NHMLFFNE_01843 2.63e-08 dltX - - S - - - D-Ala-teichoic acid biosynthesis protein
NHMLFFNE_01844 1.88e-80 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NHMLFFNE_01845 6.26e-269 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NHMLFFNE_01846 1.3e-82 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
NHMLFFNE_01847 3.63e-66 yitW - - S - - - Iron-sulfur cluster assembly protein
NHMLFFNE_01848 2.58e-158 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
NHMLFFNE_01849 3.86e-110 - 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
NHMLFFNE_01850 1.67e-163 pfoR - - S - - - COG1299 Phosphotransferase system, fructose-specific IIC component
NHMLFFNE_01851 1.35e-46 - - - S - - - YheO-like PAS domain
NHMLFFNE_01852 3.12e-08 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
NHMLFFNE_01853 2.11e-128 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
NHMLFFNE_01854 4.91e-251 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NHMLFFNE_01855 2.82e-113 msrA 1.8.4.11 - O ko:K07304 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NHMLFFNE_01856 1.7e-148 - - - M - - - PFAM NLP P60 protein
NHMLFFNE_01857 1.14e-151 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
NHMLFFNE_01858 4.99e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NHMLFFNE_01859 7.42e-89 yneR - - S - - - Belongs to the HesB IscA family
NHMLFFNE_01860 0.0 - - - S - - - membrane
NHMLFFNE_01861 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
NHMLFFNE_01862 1.53e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
NHMLFFNE_01863 4.83e-93 - - - S ko:K04750 - ko00000 3-demethylubiquinone-9 3-methyltransferase
NHMLFFNE_01864 8.81e-245 yycB - - P ko:K03449 - ko00000,ko02000 Transporter, major facilitator family protein
NHMLFFNE_01865 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NHMLFFNE_01866 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NHMLFFNE_01867 4.32e-53 - - - - - - - -
NHMLFFNE_01868 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
NHMLFFNE_01869 2.17e-256 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 Vacuole effluxer Atg22 like
NHMLFFNE_01870 9.6e-246 npp - - S - - - type I phosphodiesterase nucleotide pyrophosphatase
NHMLFFNE_01871 2.45e-315 - - - E ko:K03294 - ko00000 amino acid
NHMLFFNE_01872 5.46e-232 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NHMLFFNE_01874 1.09e-47 - 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
NHMLFFNE_01875 7.92e-206 - 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
NHMLFFNE_01876 1.29e-53 - - - S - - - Cytochrome B5
NHMLFFNE_01877 1.77e-143 - - - S - - - Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
NHMLFFNE_01879 3.43e-147 - - - S - - - GyrI-like small molecule binding domain
NHMLFFNE_01880 1.45e-160 - - - S ko:K07507 - ko00000,ko02000 MgtC family
NHMLFFNE_01881 3.37e-66 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
NHMLFFNE_01882 5.55e-245 flp - - V - - - Beta-lactamase
NHMLFFNE_01883 1.03e-96 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NHMLFFNE_01884 1.87e-117 - - - J ko:K19055 - ko00000,ko01000,ko03016 Aminoacyl-tRNA editing domain
NHMLFFNE_01885 4.38e-156 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
NHMLFFNE_01886 8.58e-130 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
NHMLFFNE_01887 3.82e-32 - - - - - - - -
NHMLFFNE_01888 2.02e-94 - - - S - - - Siphovirus Gp157
NHMLFFNE_01889 8.85e-197 - - - L - - - Helicase C-terminal domain protein
NHMLFFNE_01890 2.03e-111 - - - L - - - AAA domain
NHMLFFNE_01892 9.04e-38 - - - - - - - -
NHMLFFNE_01893 2.07e-103 - - - S - - - Bifunctional DNA primase/polymerase, N-terminal
NHMLFFNE_01894 4.84e-150 - - - S ko:K06919 - ko00000 Virulence-associated protein E
NHMLFFNE_01896 1.89e-67 - - - S - - - hydrolase activity, acting on ester bonds
NHMLFFNE_01898 1.6e-54 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NHMLFFNE_01899 6.66e-316 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
NHMLFFNE_01900 2.46e-273 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
NHMLFFNE_01901 1.8e-151 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
NHMLFFNE_01902 2.37e-80 - - - M - - - Lysin motif
NHMLFFNE_01903 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
NHMLFFNE_01904 1.53e-245 - - - S - - - Helix-turn-helix domain
NHMLFFNE_01905 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
NHMLFFNE_01906 2.15e-262 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarA family
NHMLFFNE_01907 6.83e-223 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
NHMLFFNE_01908 3.61e-96 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NHMLFFNE_01909 2.58e-85 esbA - - S - - - Family of unknown function (DUF5322)
NHMLFFNE_01910 5.39e-92 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease HI
NHMLFFNE_01911 2.56e-265 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
NHMLFFNE_01912 3.54e-277 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 Transporter, major facilitator family protein
NHMLFFNE_01913 1.53e-43 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 ThiS family
NHMLFFNE_01914 6.31e-82 moaE 2.8.1.12 - H ko:K03635,ko:K21142 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 MoaE protein
NHMLFFNE_01915 5.33e-103 - - - S - - - Flavodoxin
NHMLFFNE_01916 2.93e-164 fecD - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NHMLFFNE_01917 1.15e-162 fecE 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
NHMLFFNE_01918 2.35e-223 fecB - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
NHMLFFNE_01919 1.43e-223 - - - - - - - -
NHMLFFNE_01920 8.64e-97 - - - - - - - -
NHMLFFNE_01921 3.02e-143 - - - - - - - -
NHMLFFNE_01924 1.04e-197 - - - S - - - Calcineurin-like phosphoesterase
NHMLFFNE_01925 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
NHMLFFNE_01927 3.59e-97 - - - F - - - Nudix hydrolase
NHMLFFNE_01928 9.27e-133 gmk2 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Guanylate kinase
NHMLFFNE_01929 1.27e-108 zur - - P ko:K02076,ko:K03711 - ko00000,ko03000 Belongs to the Fur family
NHMLFFNE_01930 2.75e-37 - 3.2.1.14 GH18 - ko:K01183 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 -
NHMLFFNE_01931 1.89e-192 - - - - - - - -
NHMLFFNE_01932 3.26e-50 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain protein
NHMLFFNE_01933 2.49e-122 - - - K - - - Transcriptional regulator (TetR family)
NHMLFFNE_01934 0.0 yhgE - - V ko:K01421 - ko00000 domain protein
NHMLFFNE_01935 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 Levansucrase/Invertase
NHMLFFNE_01936 1.71e-202 rssA - - S - - - Phospholipase, patatin family
NHMLFFNE_01937 1.15e-152 - - - L - - - Integrase
NHMLFFNE_01938 1.33e-173 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
NHMLFFNE_01939 3.16e-196 yvgN - - S - - - Aldo keto reductase
NHMLFFNE_01940 1.28e-170 XK27_10500 - - K - - - response regulator
NHMLFFNE_01941 3.66e-200 kinG - - T - - - Histidine kinase-like ATPases
NHMLFFNE_01942 0.0 lysP - - E ko:K03293,ko:K11733 - ko00000,ko02000 amino acid
NHMLFFNE_01943 8.65e-09 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
NHMLFFNE_01944 3.81e-151 - - - I - - - phosphatase
NHMLFFNE_01945 6.06e-103 - - - S - - - Threonine/Serine exporter, ThrE
NHMLFFNE_01946 1.41e-164 - - - S - - - Putative threonine/serine exporter
NHMLFFNE_01947 2.22e-246 tex - - K ko:K06959 - ko00000 Tex-like protein N-terminal domain protein
NHMLFFNE_01948 5.27e-197 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NHMLFFNE_01949 0.0 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NHMLFFNE_01950 1.33e-160 yvoA_2 - - K ko:K03710 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
NHMLFFNE_01951 6.61e-167 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
NHMLFFNE_01952 0.0 - - - P ko:K07085 - ko00000 Predicted Permease Membrane Region
NHMLFFNE_01953 4.26e-187 - - - EGP - - - Major Facilitator
NHMLFFNE_01954 8.56e-115 - - - EGP - - - Major Facilitator
NHMLFFNE_01955 2e-283 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
NHMLFFNE_01956 8.95e-251 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NHMLFFNE_01957 2.29e-276 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
NHMLFFNE_01958 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NHMLFFNE_01959 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NHMLFFNE_01960 2.62e-132 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NHMLFFNE_01961 2.86e-244 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NHMLFFNE_01962 3.42e-239 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NHMLFFNE_01963 1.24e-60 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
NHMLFFNE_01964 1.39e-230 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
NHMLFFNE_01965 0.0 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NHMLFFNE_01966 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NHMLFFNE_01968 2.58e-124 - - - S - - - PFAM Archaeal ATPase
NHMLFFNE_01969 4.22e-124 - - - K - - - Cyclic nucleotide-binding domain
NHMLFFNE_01970 7.37e-166 udp 2.4.2.3 - F ko:K00757 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Phosphorylase superfamily
NHMLFFNE_01971 1.02e-177 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
NHMLFFNE_01972 3.18e-91 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
NHMLFFNE_01973 8.5e-180 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
NHMLFFNE_01974 3.77e-198 - - - L ko:K07455 - ko00000,ko03400 RecT family
NHMLFFNE_01975 4.6e-59 pi112 - - L - - - PDDEXK-like domain of unknown function (DUF3799)
NHMLFFNE_01976 1.76e-99 pi112 - - L - - - PDDEXK-like domain of unknown function (DUF3799)
NHMLFFNE_01977 2.73e-88 - - - L - - - Psort location Cytoplasmic, score
NHMLFFNE_01981 1.68e-50 - - - S - - - ORF6C domain
NHMLFFNE_01982 7.06e-224 - - - C - - - Zinc-binding dehydrogenase
NHMLFFNE_01983 5.58e-277 - - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system Galactitol-specific IIC component
NHMLFFNE_01984 1.31e-268 - - - EGP - - - Major Facilitator
NHMLFFNE_01985 4.26e-34 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
NHMLFFNE_01986 1.46e-202 gspA - - M - - - family 8
NHMLFFNE_01987 5.98e-206 - - - S - - - Alpha beta hydrolase
NHMLFFNE_01988 9.11e-123 - - - K - - - Acetyltransferase (GNAT) domain
NHMLFFNE_01989 5.2e-309 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
NHMLFFNE_01990 4.16e-51 XK27_08630 - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
NHMLFFNE_01991 2.57e-186 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
NHMLFFNE_01992 1.32e-269 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
NHMLFFNE_01993 2.45e-93 - - GT2 M ko:K12997 - ko00000,ko01000,ko01003,ko01005 Glycosyl transferase family 2
NHMLFFNE_01994 7.47e-147 - - - S - - - Glycosyltransferase like family 2
NHMLFFNE_01995 4.52e-124 - - - M - - - Glycosyltransferase like family 2
NHMLFFNE_01996 9.05e-121 cps3F - - - - - - -
NHMLFFNE_01997 1.47e-48 - - - M - - - biosynthesis protein
NHMLFFNE_01998 2.6e-105 - - - M - - - Domain of unknown function (DUF4422)
NHMLFFNE_01999 3.59e-109 - - - S - - - Glycosyltransferase like family
NHMLFFNE_02000 3.32e-139 - - - - - - - -
NHMLFFNE_02001 4.01e-184 - - - M - - - Glycosyl transferase family 2
NHMLFFNE_02003 1.05e-191 - - CBM50 NU ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NHMLFFNE_02004 2.68e-104 - - CBM50 NU ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NHMLFFNE_02005 6.64e-79 - - - S - - - Domain of unknown function DUF1829
NHMLFFNE_02006 5.51e-206 rfbA 2.7.7.24 - H ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NHMLFFNE_02007 9.64e-141 rfbC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
NHMLFFNE_02008 3.17e-261 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NHMLFFNE_02009 1.11e-200 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NHMLFFNE_02010 0.0 csd1 3.5.1.28 - M ko:K01447,ko:K17733,ko:K19117 - ko00000,ko01000,ko01002,ko01011,ko02048 N-Acetylmuramoyl-L-alanine amidase
NHMLFFNE_02011 1.31e-232 yueF - - S - - - AI-2E family transporter
NHMLFFNE_02012 2.51e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NHMLFFNE_02013 2.06e-108 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NHMLFFNE_02014 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NHMLFFNE_02015 6.49e-217 yjbO 5.4.99.23 - G ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
NHMLFFNE_02016 2.16e-198 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NHMLFFNE_02017 1.06e-149 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
NHMLFFNE_02018 2.7e-145 yjbH - - Q - - - Thioredoxin
NHMLFFNE_02019 6.82e-74 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
NHMLFFNE_02020 2.19e-220 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional regulator, LacI family
NHMLFFNE_02021 0.0 - 3.2.1.17 CBM50 NU ko:K01185,ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NHMLFFNE_02022 1.94e-66 czrA - - K ko:K22043 - ko00000,ko03000 Transcriptional regulator, ArsR family
NHMLFFNE_02023 4.81e-50 - - - - - - - -
NHMLFFNE_02024 9.24e-289 aadAT - - EK ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko01000 Aminotransferase, class I
NHMLFFNE_02025 8.31e-158 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NHMLFFNE_02026 1.39e-92 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NHMLFFNE_02027 1.1e-126 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
NHMLFFNE_02028 7.11e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NHMLFFNE_02029 9.18e-31 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
NHMLFFNE_02030 7.41e-175 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NHMLFFNE_02031 3.58e-93 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NHMLFFNE_02032 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
NHMLFFNE_02033 1.02e-235 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NHMLFFNE_02034 1.52e-88 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
NHMLFFNE_02035 2.02e-31 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
NHMLFFNE_02036 0.0 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
NHMLFFNE_02037 2.44e-11 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NHMLFFNE_02038 3.77e-123 - - - - - - - -
NHMLFFNE_02039 3.58e-119 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NHMLFFNE_02040 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
NHMLFFNE_02041 2.31e-140 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NHMLFFNE_02042 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
NHMLFFNE_02043 2.27e-215 - - - G - - - Phosphotransferase enzyme family
NHMLFFNE_02044 2.46e-72 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NHMLFFNE_02045 3.6e-107 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NHMLFFNE_02046 2.44e-100 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NHMLFFNE_02047 2.15e-85 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NHMLFFNE_02048 1.57e-296 - - - M - - - Glycosyl transferase family group 2
NHMLFFNE_02049 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
NHMLFFNE_02050 5.85e-169 gntR - - K - - - UbiC transcription regulator-associated domain protein
NHMLFFNE_02051 2.75e-105 - - - S - - - Protein of unknown function (DUF805)
NHMLFFNE_02052 1.26e-60 - - - - - - - -
NHMLFFNE_02053 0.0 nylA 3.5.1.4 - J ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 ko00000,ko00001,ko01000 Belongs to the amidase family
NHMLFFNE_02054 6.89e-36 - - - S - - - Sulphur transport
NHMLFFNE_02055 1.51e-277 mtnE - - E ko:K08969 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
NHMLFFNE_02056 1.01e-178 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Carbon-nitrogen hydrolase
NHMLFFNE_02057 1.73e-175 proB 2.7.2.11 - F ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NHMLFFNE_02058 4.95e-288 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NHMLFFNE_02059 3.62e-170 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NHMLFFNE_02060 4.99e-252 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NHMLFFNE_02061 3.02e-135 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 Ribosomal-protein-alanine acetyltransferase
NHMLFFNE_02062 1.13e-165 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
NHMLFFNE_02063 1.48e-247 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
NHMLFFNE_02064 4.59e-222 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
NHMLFFNE_02065 0.0 ppk 2.7.4.1 - P ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NHMLFFNE_02066 0.0 ppx3 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
NHMLFFNE_02067 6.09e-176 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
NHMLFFNE_02068 6.39e-200 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NHMLFFNE_02069 3.71e-76 yabA - - L - - - Involved in initiation control of chromosome replication
NHMLFFNE_02070 1.06e-234 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
NHMLFFNE_02071 2.83e-69 yaaQ - - S - - - Cyclic-di-AMP receptor
NHMLFFNE_02072 5.48e-150 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NHMLFFNE_02073 4.67e-52 - - - S - - - Protein of unknown function (DUF2508)
NHMLFFNE_02074 1.65e-140 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NHMLFFNE_02075 2.39e-61 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NHMLFFNE_02076 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NHMLFFNE_02077 2.08e-117 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NHMLFFNE_02078 3.8e-47 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
NHMLFFNE_02079 4.56e-211 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
NHMLFFNE_02080 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NHMLFFNE_02081 9.63e-39 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
NHMLFFNE_02082 1.84e-295 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
NHMLFFNE_02083 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NHMLFFNE_02084 2.84e-73 - - - S - - - Sugar efflux transporter for intercellular exchange
NHMLFFNE_02085 9.2e-317 - 1.8.1.7 - C ko:K00383,ko:K21739 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Pyridine nucleotide-disulfide oxidoreductase
NHMLFFNE_02087 0.0 - - - L - - - Helicase C-terminal domain protein
NHMLFFNE_02088 6.68e-103 - 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 PAP2 superfamily
NHMLFFNE_02089 9.37e-228 ydhF - - S - - - Aldo keto reductase
NHMLFFNE_02090 4.76e-143 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NHMLFFNE_02091 5.71e-265 adh 1.1.1.1 - C ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Zinc-binding alcohol dehydrogenase family protein
NHMLFFNE_02092 3.8e-276 - - - L - - - PFAM plasmid pRiA4b ORF-3 family protein
NHMLFFNE_02093 1.23e-79 - - - L - - - PFAM plasmid pRiA4b ORF-3 family protein
NHMLFFNE_02094 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 associated with various cellular activities
NHMLFFNE_02095 8.68e-44 - - - - - - - -
NHMLFFNE_02096 1.72e-133 int3 - - L - - - Belongs to the 'phage' integrase family
NHMLFFNE_02098 2.82e-87 - - - S - - - IrrE N-terminal-like domain
NHMLFFNE_02099 3.46e-39 - - - K - - - Helix-turn-helix domain
NHMLFFNE_02100 2.34e-16 - - - - - - - -
NHMLFFNE_02103 0.0 FbpA - - K - - - Fibronectin-binding protein
NHMLFFNE_02104 2.95e-207 - - - S - - - EDD domain protein, DegV family
NHMLFFNE_02105 9.14e-125 - - - - - - - -
NHMLFFNE_02106 1.36e-106 - - - - - - - -
NHMLFFNE_02107 1.45e-313 yijG - GT2 M ko:K11936 ko02026,map02026 ko00000,ko00001,ko01000,ko01003,ko02000 Glycosyl transferase
NHMLFFNE_02108 2.04e-175 - - - T - - - EAL domain
NHMLFFNE_02109 4.39e-51 - - - L - - - Integrase
NHMLFFNE_02110 1.49e-251 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NHMLFFNE_02111 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NHMLFFNE_02112 8.71e-148 dedA - - S ko:K03975 - ko00000 SNARE-like domain protein
NHMLFFNE_02113 1.12e-135 - - - S - - - Protein of unknown function (DUF1461)
NHMLFFNE_02114 7.88e-169 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NHMLFFNE_02115 3.24e-121 yutD - - S - - - Protein of unknown function (DUF1027)
NHMLFFNE_02116 7.7e-41 - - - S - - - Calcineurin-like phosphoesterase
NHMLFFNE_02117 2.16e-06 - - - S - - - Helix-turn-helix domain
NHMLFFNE_02118 7.48e-57 - - - S - - - Phage regulatory protein Rha (Phage_pRha)
NHMLFFNE_02119 3.06e-36 - - - - - - - -
NHMLFFNE_02120 3.44e-18 - - - - - - - -
NHMLFFNE_02121 1.17e-12 ansR - - K - - - Transcriptional regulator
NHMLFFNE_02127 1.89e-47 - - - LM - - - gp58-like protein
NHMLFFNE_02128 3.11e-173 - - - M - - - Prophage endopeptidase tail
NHMLFFNE_02129 4.85e-105 - - - S - - - Phage tail protein
NHMLFFNE_02130 0.0 - - - L - - - Phage tail tape measure protein TP901
NHMLFFNE_02131 2.92e-13 - - - S - - - Phage tail assembly chaperone proteins, TAC
NHMLFFNE_02132 6e-102 - - - S - - - Phage tail tube protein
NHMLFFNE_02136 6.67e-67 - - - S - - - Phage gp6-like head-tail connector protein
NHMLFFNE_02137 6.45e-252 - - - S - - - Phage capsid family
NHMLFFNE_02138 8.21e-80 - - - S - - - Clp protease
NHMLFFNE_02139 3.72e-263 - - - S - - - Phage portal protein
NHMLFFNE_02141 0.0 - - - S - - - Phage Terminase
NHMLFFNE_02142 1.99e-84 - - - L - - - Phage terminase, small subunit
NHMLFFNE_02143 2.36e-102 - - - L - - - HNH nucleases
NHMLFFNE_02144 1.44e-59 - - - S - - - HicB_like antitoxin of bacterial toxin-antitoxin system
NHMLFFNE_02145 4.87e-28 - - - N - - - HicA toxin of bacterial toxin-antitoxin,
NHMLFFNE_02146 3.27e-236 coiA - - S ko:K06198 - ko00000 Competence protein
NHMLFFNE_02147 5.44e-155 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
NHMLFFNE_02148 1.37e-86 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NHMLFFNE_02149 1.31e-103 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
NHMLFFNE_02150 8.39e-313 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
NHMLFFNE_02151 3.84e-316 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
NHMLFFNE_02152 5.94e-128 - - - S - - - Family of unknown function (DUF5449)
NHMLFFNE_02153 9.44e-234 - 4.1.1.22 - H ko:K01590 ko00340,ko01100,ko01110,map00340,map01100,map01110 ko00000,ko00001,ko01000 Histidine carboxylase PI chain
NHMLFFNE_02154 0.0 - - - E ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
NHMLFFNE_02156 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NHMLFFNE_02157 1.15e-67 - - - S ko:K19157 - ko00000,ko01000,ko02048 Bacterial toxin of type II toxin-antitoxin system, YafQ
NHMLFFNE_02158 8.83e-57 - - - S ko:K07473 - ko00000,ko02048 RelB antitoxin
NHMLFFNE_02159 2.48e-52 - - - L ko:K07483 - ko00000 Transposase and inactivated derivatives
NHMLFFNE_02160 2.67e-75 is18 - - L - - - Integrase core domain
NHMLFFNE_02163 6.26e-96 - - - - - - - -
NHMLFFNE_02164 2.66e-280 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
NHMLFFNE_02165 8.27e-180 - - - V - - - Beta-lactamase enzyme family
NHMLFFNE_02166 5.23e-92 pepD1 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
NHMLFFNE_02167 2.8e-97 pepD1 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
NHMLFFNE_02168 6.51e-305 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
NHMLFFNE_02169 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
NHMLFFNE_02170 5.69e-105 - - - - - - - -
NHMLFFNE_02171 4.97e-159 - - - M - - - Lysin motif
NHMLFFNE_02172 5.75e-250 - - - EGP - - - Major Facilitator
NHMLFFNE_02173 1.68e-226 codA 3.5.4.1 - F ko:K01485 ko00240,ko00330,ko01100,map00240,map00330,map01100 ko00000,ko00001,ko01000 cytosine deaminase
NHMLFFNE_02174 1.71e-50 codA 3.5.4.1 - F ko:K01485 ko00240,ko00330,ko01100,map00240,map00330,map01100 ko00000,ko00001,ko01000 cytosine deaminase
NHMLFFNE_02175 0.0 - - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
NHMLFFNE_02176 3.39e-194 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NHMLFFNE_02177 2.62e-142 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
NHMLFFNE_02178 1.74e-179 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
NHMLFFNE_02179 5.35e-113 - - - T - - - Belongs to the universal stress protein A family
NHMLFFNE_02180 2.45e-62 - - - M - - - MucBP domain
NHMLFFNE_02183 9.36e-48 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NHMLFFNE_02184 6.92e-113 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NHMLFFNE_02185 4.55e-64 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
NHMLFFNE_02186 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NHMLFFNE_02187 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NHMLFFNE_02188 5.69e-260 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NHMLFFNE_02189 3.13e-46 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain protein YaaA
NHMLFFNE_02190 2.84e-263 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NHMLFFNE_02191 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NHMLFFNE_02192 7.96e-21 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
NHMLFFNE_02193 5.68e-76 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NHMLFFNE_02194 2e-170 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NHMLFFNE_02195 8.89e-170 jag - - S ko:K06346 - ko00000 R3H domain protein
NHMLFFNE_02196 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NHMLFFNE_02197 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NHMLFFNE_02198 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
NHMLFFNE_02199 0.0 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NHMLFFNE_02200 8.59e-314 yxbA 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp enzyme
NHMLFFNE_02201 4.32e-146 - - - M - - - LysM domain protein
NHMLFFNE_02202 3.7e-203 - - - O - - - Uncharacterized protein family (UPF0051)
NHMLFFNE_02203 2.77e-144 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NHMLFFNE_02204 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
NHMLFFNE_02205 1.51e-302 lmrB - - U ko:K18926 - ko00000,ko00002,ko02000 Belongs to the major facilitator superfamily
NHMLFFNE_02206 1.81e-50 - - - L - - - transposase activity
NHMLFFNE_02207 8.33e-129 - - - S - - - N-methyltransferase activity
NHMLFFNE_02208 3.65e-82 - - - KL - - - DNA methylase
NHMLFFNE_02209 1.43e-111 - - - S ko:K19055 - ko00000,ko01000,ko03016 Aminoacyl-tRNA editing domain
NHMLFFNE_02210 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NHMLFFNE_02211 1.83e-59 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NHMLFFNE_02212 9.34e-07 - - - S - - - Helix-turn-helix domain
NHMLFFNE_02213 1.07e-15 - - - S - - - Phage regulatory protein, Rha family
NHMLFFNE_02215 9.17e-25 - - - S - - - Helix-turn-helix domain
NHMLFFNE_02216 2.4e-20 ansR - - K - - - Transcriptional regulator
NHMLFFNE_02217 0.0 - - - M - - - NlpC/P60 family
NHMLFFNE_02218 0.0 - - - S - - - Peptidase, M23
NHMLFFNE_02219 3.26e-93 - - - S - - - Peptidase, M23
NHMLFFNE_02220 5.22e-68 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
NHMLFFNE_02221 2.08e-240 ybcH - - D ko:K06889 - ko00000 Alpha beta
NHMLFFNE_02222 1.3e-95 - - - K - - - Transcriptional regulator
NHMLFFNE_02223 1.41e-204 - - - - - - - -
NHMLFFNE_02224 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NHMLFFNE_02225 2.8e-93 - - - S - - - Metallo-beta-lactamase superfamily
NHMLFFNE_02226 1.44e-47 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
NHMLFFNE_02227 1.74e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NHMLFFNE_02228 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NHMLFFNE_02229 0.0 - - - S ko:K13730 ko05100,map05100 ko00000,ko00001 Uncharacterized protein conserved in bacteria (DUF2252)
NHMLFFNE_02230 8.23e-39 - - - - - - - -
NHMLFFNE_02231 1.28e-255 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
NHMLFFNE_02232 1.89e-262 - - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
NHMLFFNE_02233 3.11e-224 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NHMLFFNE_02234 9.74e-98 - - - O - - - OsmC-like protein
NHMLFFNE_02235 2.59e-144 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
NHMLFFNE_02236 4.1e-120 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NHMLFFNE_02237 1.21e-245 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NHMLFFNE_02238 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 ABC transporter, ATP-binding protein
NHMLFFNE_02239 2.35e-285 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NHMLFFNE_02240 3.18e-299 XK27_05225 - - S - - - Tetratricopeptide repeat protein
NHMLFFNE_02241 1.88e-192 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
NHMLFFNE_02242 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
NHMLFFNE_02243 9.01e-119 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
NHMLFFNE_02244 1.01e-115 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
NHMLFFNE_02245 1.61e-136 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
NHMLFFNE_02246 2.12e-252 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
NHMLFFNE_02247 3.05e-116 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NHMLFFNE_02248 9.66e-129 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
NHMLFFNE_02249 9.06e-60 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
NHMLFFNE_02250 1.07e-283 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
NHMLFFNE_02251 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
NHMLFFNE_02252 2.28e-173 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the inositol monophosphatase superfamily
NHMLFFNE_02253 7.04e-63 yktA - - S - - - Belongs to the UPF0223 family
NHMLFFNE_02254 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
NHMLFFNE_02255 4.49e-313 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NHMLFFNE_02256 3.28e-232 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Transketolase, C-terminal domain protein
NHMLFFNE_02257 4.05e-266 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
NHMLFFNE_02258 1.38e-132 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NHMLFFNE_02259 3.97e-107 - - - - - - - -
NHMLFFNE_02260 9.99e-44 ykzG - - S - - - Belongs to the UPF0356 family
NHMLFFNE_02261 1.57e-234 - - - I - - - Diacylglycerol kinase catalytic
NHMLFFNE_02262 8.83e-39 - - - - - - - -
NHMLFFNE_02263 2.49e-243 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
NHMLFFNE_02264 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NHMLFFNE_02265 2.18e-232 - - - EGP - - - Major Facilitator
NHMLFFNE_02266 2.94e-148 - - - IQ - - - dehydrogenase reductase
NHMLFFNE_02267 4.54e-49 - - - - - - - -
NHMLFFNE_02268 7.73e-147 - - - S ko:K07118 - ko00000 NAD(P)H-binding
NHMLFFNE_02269 1.89e-51 - - - S - - - Cytochrome b5-like Heme/Steroid binding domain
NHMLFFNE_02270 6.28e-245 ampC - - V - - - Beta-lactamase
NHMLFFNE_02271 9.87e-16 - - - - - - - -
NHMLFFNE_02272 2.38e-130 - - - M - - - domain protein
NHMLFFNE_02273 4.91e-63 - - - S - - - Calcineurin-like phosphoesterase
NHMLFFNE_02274 1.03e-281 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NHMLFFNE_02275 2.07e-185 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
NHMLFFNE_02285 2.6e-33 - - - - - - - -
NHMLFFNE_02286 1.84e-140 - - - - - - - -
NHMLFFNE_02287 4.78e-271 yttB - - EGP - - - Major Facilitator
NHMLFFNE_02289 6.05e-111 - - - KL - - - Type III restriction enzyme res subunit
NHMLFFNE_02290 6.79e-207 cobT 2.4.2.21 - F ko:K00768 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)
NHMLFFNE_02291 1.39e-168 - - - H - - - Uroporphyrinogen-III synthase
NHMLFFNE_02292 3.23e-145 cobC 3.1.3.73 - G ko:K02226 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
NHMLFFNE_02293 1.68e-29 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
NHMLFFNE_02294 5e-108 - - - S - - - Putative HNHc nuclease
NHMLFFNE_02295 8.46e-55 - - - S - - - ERF superfamily

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)