ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
MLHAJGEM_00003 9.76e-93 - - - - - - - -
MLHAJGEM_00004 9.03e-16 - - - - - - - -
MLHAJGEM_00005 3.89e-237 - - - - - - - -
MLHAJGEM_00006 4.91e-117 gtcA1 - - S - - - Teichoic acid glycosylation protein
MLHAJGEM_00007 8.01e-77 - - - S - - - Protein of unknown function (DUF1516)
MLHAJGEM_00008 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
MLHAJGEM_00009 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MLHAJGEM_00010 0.0 - - - S - - - Protein conserved in bacteria
MLHAJGEM_00011 8.91e-293 sat 2.7.7.4 - H ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms
MLHAJGEM_00012 1.25e-143 cysC 2.7.1.25 - F ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
MLHAJGEM_00013 5.99e-224 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain
MLHAJGEM_00014 0.0 astA 2.8.2.22 - M ko:K01023 - ko00000,ko01000 Arylsulfotransferase Ig-like domain
MLHAJGEM_00015 0.0 - - - P - - - Sodium:sulfate symporter transmembrane region
MLHAJGEM_00016 6.28e-316 dinF - - V - - - MatE
MLHAJGEM_00017 1.79e-42 - - - - - - - -
MLHAJGEM_00020 3.48e-103 yybD - - S ko:K02348 - ko00000 Acetyltransferase (GNAT) domain
MLHAJGEM_00021 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
MLHAJGEM_00022 3.81e-105 - - - - - - - -
MLHAJGEM_00023 0.0 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
MLHAJGEM_00024 6.25e-138 - - - - - - - -
MLHAJGEM_00025 0.0 celR - - K - - - PRD domain
MLHAJGEM_00026 6.97e-76 celR - - K - - - PRD domain
MLHAJGEM_00027 5.44e-104 - - - S - - - Domain of unknown function (DUF3284)
MLHAJGEM_00028 2.37e-68 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
MLHAJGEM_00029 4.9e-64 - 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
MLHAJGEM_00030 4.85e-284 - - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MLHAJGEM_00031 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MLHAJGEM_00032 2.8e-176 - - - EGP ko:K08218 ko01501,map01501 ko00000,ko00001,ko00002,ko02000 Major facilitator Superfamily
MLHAJGEM_00033 1.55e-76 - - - EGP ko:K08218 ko01501,map01501 ko00000,ko00001,ko00002,ko02000 Major facilitator Superfamily
MLHAJGEM_00034 1.72e-148 yciB - - M - - - ErfK YbiS YcfS YnhG
MLHAJGEM_00035 1.65e-46 dltC2 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLHAJGEM_00036 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 Alanine-glyoxylate amino-transferase
MLHAJGEM_00037 3.29e-132 argO - - S ko:K06895 - ko00000,ko02000 LysE type translocator
MLHAJGEM_00038 2.18e-268 arcT - - E - - - Aminotransferase
MLHAJGEM_00039 2.07e-102 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
MLHAJGEM_00040 4.06e-17 - - - - - - - -
MLHAJGEM_00041 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
MLHAJGEM_00042 9.94e-71 yheA - - S - - - Belongs to the UPF0342 family
MLHAJGEM_00043 4.47e-296 yhaO - - L ko:K03547 - ko00000,ko03400 Ser Thr phosphatase family protein
MLHAJGEM_00044 0.0 yhaN - - L - - - AAA domain
MLHAJGEM_00045 3.45e-239 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 Metal dependent phosphohydrolases with conserved 'HD' motif.
MLHAJGEM_00046 3.55e-274 - - - - - - - -
MLHAJGEM_00047 1.34e-230 - - - M - - - Peptidase family S41
MLHAJGEM_00048 6.59e-227 - - - K - - - LysR substrate binding domain
MLHAJGEM_00049 5.73e-143 - - - S - - - NADPH-dependent FMN reductase
MLHAJGEM_00050 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
MLHAJGEM_00051 2.57e-128 - - - - - - - -
MLHAJGEM_00052 2.27e-98 - 2.4.2.6 - F ko:K08728 ko00240,map00240 ko00000,ko00001,ko01000 Nucleoside 2-deoxyribosyltransferase
MLHAJGEM_00053 0.0 - - - M - - - domain protein
MLHAJGEM_00054 1.15e-235 ykoT - - M - - - Glycosyl transferase family 2
MLHAJGEM_00055 0.0 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MLHAJGEM_00056 2.31e-23 - - - S - - - NUDIX domain
MLHAJGEM_00057 0.0 - - - S - - - membrane
MLHAJGEM_00058 4.26e-218 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MLHAJGEM_00059 1.06e-111 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
MLHAJGEM_00060 2.96e-284 ribA 3.5.4.25, 4.1.99.12 - H ko:K02858,ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
MLHAJGEM_00061 5.84e-105 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
MLHAJGEM_00062 5.21e-137 - - - S ko:K09962 - ko00000 Nucleotidyltransferase
MLHAJGEM_00063 5.62e-137 - - - - - - - -
MLHAJGEM_00064 3.3e-151 crp2 - - K ko:K10914,ko:K21562 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 helix_turn_helix, cAMP Regulatory protein
MLHAJGEM_00065 4.89e-146 - - - K - - - Bacterial regulatory proteins, tetR family
MLHAJGEM_00066 6.06e-308 npr 1.11.1.1 - C ko:K05910 - ko00000,ko01000 NADH oxidase
MLHAJGEM_00067 0.0 - - - - - - - -
MLHAJGEM_00068 1.12e-78 - - - - - - - -
MLHAJGEM_00069 1.08e-244 - - - S - - - Fn3-like domain
MLHAJGEM_00070 2.82e-138 - - - S - - - WxL domain surface cell wall-binding
MLHAJGEM_00071 5.76e-135 - - - S - - - WxL domain surface cell wall-binding
MLHAJGEM_00072 1.09e-196 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MLHAJGEM_00073 6.76e-73 - - - - - - - -
MLHAJGEM_00074 3.6e-106 hit - - FG ko:K02503 - ko00000,ko04147 histidine triad
MLHAJGEM_00075 4.47e-174 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MLHAJGEM_00076 8.17e-285 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
MLHAJGEM_00077 7.24e-197 ytmP - - M - - - Choline/ethanolamine kinase
MLHAJGEM_00078 4.7e-156 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MLHAJGEM_00079 2.94e-71 ytzB - - S - - - Peptidase propeptide and YPEB domain
MLHAJGEM_00080 4.32e-147 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MLHAJGEM_00081 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
MLHAJGEM_00082 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
MLHAJGEM_00083 3.04e-29 - - - S - - - Virus attachment protein p12 family
MLHAJGEM_00084 0.0 feoB - - P ko:K04759 - ko00000,ko02000 transporter of a GTP-driven Fe(2 ) uptake system
MLHAJGEM_00085 2.87e-47 feoA - - P ko:K04758 - ko00000,ko02000 FeoA domain
MLHAJGEM_00086 3.14e-184 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
MLHAJGEM_00087 5.21e-311 sufD - - O ko:K07033,ko:K09015 - ko00000 FeS assembly protein SufD
MLHAJGEM_00088 1.57e-299 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MLHAJGEM_00089 2.23e-107 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
MLHAJGEM_00090 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
MLHAJGEM_00091 4.07e-60 - - - S - - - Iron-sulfur cluster assembly protein
MLHAJGEM_00092 1.72e-140 - - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
MLHAJGEM_00093 8.51e-155 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
MLHAJGEM_00094 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MLHAJGEM_00095 2.52e-199 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MLHAJGEM_00096 9.54e-134 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MLHAJGEM_00097 1.58e-117 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MLHAJGEM_00098 1.61e-315 dnaB - - L ko:K03346 - ko00000,ko03032 replication initiation and membrane attachment
MLHAJGEM_00099 6.05e-221 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
MLHAJGEM_00100 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MLHAJGEM_00101 2.37e-109 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MLHAJGEM_00102 6.92e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
MLHAJGEM_00103 6.88e-73 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MLHAJGEM_00104 9.27e-73 - - - - - - - -
MLHAJGEM_00105 1.16e-305 - - - L ko:K07478 - ko00000 AAA C-terminal domain
MLHAJGEM_00106 3.94e-235 qor 1.1.1.1, 1.6.5.5 - C ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
MLHAJGEM_00107 1.64e-83 ydeP - - K - - - Transcriptional regulator, HxlR family
MLHAJGEM_00108 2.39e-175 racD 5.1.1.13 - G ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
MLHAJGEM_00109 3.92e-191 yijG - GT2 M ko:K11936 ko02026,map02026 ko00000,ko00001,ko01000,ko01003,ko02000 Glycosyl transferase
MLHAJGEM_00110 4.96e-85 yijG - GT2 M ko:K11936 ko02026,map02026 ko00000,ko00001,ko01000,ko01003,ko02000 Glycosyl transferase
MLHAJGEM_00111 6.32e-114 - - - - - - - -
MLHAJGEM_00112 5.7e-127 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
MLHAJGEM_00113 7.7e-276 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
MLHAJGEM_00114 4.25e-65 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein
MLHAJGEM_00115 4.19e-153 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MLHAJGEM_00116 1.71e-149 yqeK - - H - - - Hydrolase, HD family
MLHAJGEM_00117 1.06e-76 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MLHAJGEM_00118 2.05e-174 yqeM - - Q - - - Methyltransferase
MLHAJGEM_00119 1.09e-273 ylbM - - S - - - Belongs to the UPF0348 family
MLHAJGEM_00120 3.66e-127 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
MLHAJGEM_00121 1.3e-125 - - - S - - - Peptidase propeptide and YPEB domain
MLHAJGEM_00122 1.8e-222 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MLHAJGEM_00123 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MLHAJGEM_00124 7.66e-312 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
MLHAJGEM_00125 1.38e-155 csrR - - K - - - response regulator
MLHAJGEM_00126 0.0 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MLHAJGEM_00127 1.93e-218 ubiA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
MLHAJGEM_00128 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 Putative exonuclease SbcCD, C subunit
MLHAJGEM_00129 7.88e-288 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
MLHAJGEM_00130 1.77e-122 - - - S - - - SdpI/YhfL protein family
MLHAJGEM_00131 1.4e-208 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MLHAJGEM_00132 2.36e-60 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
MLHAJGEM_00133 4.46e-179 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MLHAJGEM_00134 1.72e-120 XK27_09705 - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
MLHAJGEM_00135 1.09e-83 yodB - - K - - - Transcriptional regulator, HxlR family
MLHAJGEM_00136 1.14e-255 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MLHAJGEM_00137 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MLHAJGEM_00138 6.11e-249 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MLHAJGEM_00139 7.5e-146 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
MLHAJGEM_00140 1.09e-105 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MLHAJGEM_00141 4.61e-144 - - - S - - - membrane
MLHAJGEM_00142 5.72e-99 - - - K - - - LytTr DNA-binding domain
MLHAJGEM_00143 6.12e-72 yneR - - S - - - Belongs to the HesB IscA family
MLHAJGEM_00144 0.0 - - - S - - - membrane
MLHAJGEM_00145 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
MLHAJGEM_00146 5.33e-30 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
MLHAJGEM_00147 9.29e-132 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MLHAJGEM_00148 8.28e-152 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Peptidase, S54 family
MLHAJGEM_00149 6.33e-46 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
MLHAJGEM_00150 2.6e-231 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
MLHAJGEM_00151 1.62e-141 pepE 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
MLHAJGEM_00152 1.15e-89 yqhL - - P - - - Rhodanese-like protein
MLHAJGEM_00153 1.44e-31 WQ51_02665 - - S - - - Protein of unknown function (DUF3042)
MLHAJGEM_00154 1.83e-177 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 phosphodiesterase
MLHAJGEM_00155 2.29e-225 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MLHAJGEM_00156 7.79e-85 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 Transcriptional regulator
MLHAJGEM_00157 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
MLHAJGEM_00158 1.77e-205 - - - - - - - -
MLHAJGEM_00159 1.1e-231 - - - - - - - -
MLHAJGEM_00160 4.14e-126 - - - S - - - Protein conserved in bacteria
MLHAJGEM_00161 3.11e-73 - - - - - - - -
MLHAJGEM_00162 2.97e-41 - - - - - - - -
MLHAJGEM_00165 9.81e-27 - - - - - - - -
MLHAJGEM_00166 8.15e-125 - - - K - - - Transcriptional regulator
MLHAJGEM_00167 1.55e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
MLHAJGEM_00168 7.97e-71 ysxB - - J ko:K07584 - ko00000 Cysteine protease Prp
MLHAJGEM_00169 4.71e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
MLHAJGEM_00170 5.79e-247 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
MLHAJGEM_00171 1.43e-129 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MLHAJGEM_00172 1.7e-96 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
MLHAJGEM_00173 1.63e-90 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MLHAJGEM_00174 1.96e-193 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MLHAJGEM_00175 8.06e-313 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MLHAJGEM_00176 7.55e-44 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MLHAJGEM_00177 5.26e-203 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
MLHAJGEM_00178 4.49e-192 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
MLHAJGEM_00179 6.17e-99 argR2 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
MLHAJGEM_00180 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
MLHAJGEM_00181 4.51e-284 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MLHAJGEM_00182 2.89e-134 opuCB - - E ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MLHAJGEM_00183 3.8e-224 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MLHAJGEM_00184 1.36e-136 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MLHAJGEM_00185 8.28e-73 - - - - - - - -
MLHAJGEM_00186 6.96e-145 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
MLHAJGEM_00187 3.93e-41 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MLHAJGEM_00188 2.39e-276 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MLHAJGEM_00189 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MLHAJGEM_00190 5.2e-225 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MLHAJGEM_00191 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MLHAJGEM_00192 1.62e-173 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
MLHAJGEM_00193 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
MLHAJGEM_00194 1.21e-209 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MLHAJGEM_00195 5.24e-150 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
MLHAJGEM_00196 1.51e-159 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
MLHAJGEM_00197 1.61e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
MLHAJGEM_00198 7.09e-76 yloU - - S - - - Asp23 family, cell envelope-related function
MLHAJGEM_00199 0.0 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
MLHAJGEM_00200 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MLHAJGEM_00201 3.6e-243 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MLHAJGEM_00202 3.33e-47 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
MLHAJGEM_00203 4.49e-167 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MLHAJGEM_00204 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
MLHAJGEM_00205 2.85e-293 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MLHAJGEM_00206 1.46e-77 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MLHAJGEM_00207 9.38e-301 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MLHAJGEM_00208 1.6e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
MLHAJGEM_00209 9.99e-53 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
MLHAJGEM_00210 2.24e-123 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MLHAJGEM_00211 1.57e-179 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
MLHAJGEM_00212 3.15e-78 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MLHAJGEM_00213 6.21e-68 - - - - - - - -
MLHAJGEM_00214 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
MLHAJGEM_00215 1.1e-112 - - - - - - - -
MLHAJGEM_00216 1.18e-178 ecsA_2 - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
MLHAJGEM_00217 0.0 XK27_00765 - - - ko:K01992 - ko00000,ko00002,ko02000 -
MLHAJGEM_00219 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Anthranilate synthase component I, N terminal region
MLHAJGEM_00220 8.08e-135 trpG 4.1.3.27 - EH ko:K01658 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Peptidase C26
MLHAJGEM_00221 8.2e-224 trpD 2.4.2.18, 4.1.3.27 - F ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MLHAJGEM_00222 2.31e-163 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
MLHAJGEM_00223 1.57e-142 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
MLHAJGEM_00224 8.5e-286 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MLHAJGEM_00225 2.29e-181 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
MLHAJGEM_00226 1.02e-126 entB - - Q - - - Isochorismatase family
MLHAJGEM_00227 6.1e-228 - 1.6.5.5 - C ko:K00344 - ko00000,ko01000 Zinc-binding dehydrogenase
MLHAJGEM_00228 1.95e-88 ybbJ - - K - - - Acetyltransferase (GNAT) family
MLHAJGEM_00229 5.17e-273 - - - E - - - glutamate:sodium symporter activity
MLHAJGEM_00230 2.28e-272 hipO1 - - E ko:K21613 - ko00000,ko01000,ko01002 Peptidase family M20/M25/M40
MLHAJGEM_00231 8.04e-254 adhB 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
MLHAJGEM_00232 1.09e-79 - - - S - - - Protein of unknown function (DUF1648)
MLHAJGEM_00233 9.32e-184 yneD - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
MLHAJGEM_00234 8.02e-230 yneE - - K - - - Transcriptional regulator
MLHAJGEM_00235 8.55e-99 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MLHAJGEM_00236 2.3e-229 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MLHAJGEM_00237 1.06e-48 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
MLHAJGEM_00238 8.52e-216 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
MLHAJGEM_00239 1.26e-162 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
MLHAJGEM_00240 5.38e-290 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MLHAJGEM_00241 5.25e-96 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MLHAJGEM_00242 7.23e-93 fabZ2 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
MLHAJGEM_00243 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
MLHAJGEM_00244 8.76e-201 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MLHAJGEM_00245 1.96e-178 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 alpha subunit
MLHAJGEM_00246 1.55e-173 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
MLHAJGEM_00247 5.01e-129 - - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
MLHAJGEM_00248 3.64e-162 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
MLHAJGEM_00249 3.73e-207 - - - K - - - LysR substrate binding domain
MLHAJGEM_00250 4.94e-114 ykhA - - I - - - Thioesterase superfamily
MLHAJGEM_00251 2.66e-247 rsgA_2 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MLHAJGEM_00252 6.05e-121 - - - K - - - transcriptional regulator
MLHAJGEM_00253 0.0 - - - EGP - - - Major Facilitator
MLHAJGEM_00254 1.14e-193 - - - O - - - Band 7 protein
MLHAJGEM_00255 2.46e-70 - - - - - - - -
MLHAJGEM_00256 2.02e-39 - - - - - - - -
MLHAJGEM_00257 4.63e-274 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
MLHAJGEM_00258 9.96e-147 - 1.14.99.53 AA10 S ko:K21713 - ko00000,ko01000 Lytic polysaccharide mono-oxygenase, cellulose-degrading
MLHAJGEM_00259 1.45e-60 ycnE - - S - - - Antibiotic biosynthesis monooxygenase
MLHAJGEM_00260 2.05e-55 - - - - - - - -
MLHAJGEM_00261 6.05e-108 tspO - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 TspO/MBR family
MLHAJGEM_00262 5.28e-100 - - - T - - - Belongs to the universal stress protein A family
MLHAJGEM_00263 3.92e-87 - - - S - - - Protein of unknown function (DUF805)
MLHAJGEM_00264 1.03e-210 - - - I - - - Diacylglycerol kinase catalytic domain
MLHAJGEM_00265 1.51e-48 - - - - - - - -
MLHAJGEM_00266 5.79e-21 - - - - - - - -
MLHAJGEM_00267 1.29e-54 - - - S - - - transglycosylase associated protein
MLHAJGEM_00268 4e-40 - - - S - - - CsbD-like
MLHAJGEM_00269 3.04e-53 - - - - - - - -
MLHAJGEM_00270 0.0 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
MLHAJGEM_00271 8.39e-38 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
MLHAJGEM_00272 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MLHAJGEM_00273 1.04e-218 - 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 UbiA prenyltransferase family
MLHAJGEM_00274 5.03e-182 - - - U ko:K10716 - ko00000,ko02000 Ion channel
MLHAJGEM_00275 7.23e-66 - - - - - - - -
MLHAJGEM_00276 8.94e-56 - - - - - - - -
MLHAJGEM_00277 0.0 gabT 2.6.1.19, 5.1.1.21 - E ko:K00823,ko:K20708 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MLHAJGEM_00278 0.0 - - - E ko:K03294 - ko00000 Amino Acid
MLHAJGEM_00279 1.57e-191 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
MLHAJGEM_00280 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
MLHAJGEM_00281 8.83e-153 - - - S - - - Domain of unknown function (DUF4767)
MLHAJGEM_00283 0.0 malT - - G ko:K16211 - ko00000,ko02000 Major Facilitator
MLHAJGEM_00284 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
MLHAJGEM_00285 3.36e-247 galM2 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
MLHAJGEM_00286 4.98e-250 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MLHAJGEM_00287 7.22e-262 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
MLHAJGEM_00288 1.1e-230 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
MLHAJGEM_00289 2.98e-217 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 mevalonate kinase
MLHAJGEM_00290 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
MLHAJGEM_00291 2.53e-107 ypmB - - S - - - protein conserved in bacteria
MLHAJGEM_00292 1.04e-287 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
MLHAJGEM_00293 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
MLHAJGEM_00294 1.13e-165 dnaD - - L ko:K02086 - ko00000 Replication initiation and membrane attachment
MLHAJGEM_00296 3.44e-240 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MLHAJGEM_00297 2.45e-142 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MLHAJGEM_00298 3.19e-203 metQ1 - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
MLHAJGEM_00299 5.32e-109 - - - T - - - Universal stress protein family
MLHAJGEM_00300 0.0 ftpA - - P ko:K02011 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MLHAJGEM_00301 4.66e-233 ftpB - - P ko:K02012 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
MLHAJGEM_00302 8.03e-229 phnT 3.6.3.30 - P ko:K02010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
MLHAJGEM_00303 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
MLHAJGEM_00304 1.47e-151 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MLHAJGEM_00305 2.12e-142 ypsA - - S - - - Belongs to the UPF0398 family
MLHAJGEM_00306 9.98e-75 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MLHAJGEM_00308 1.44e-282 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
MLHAJGEM_00309 4.17e-186 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
MLHAJGEM_00310 1.93e-96 - - - S - - - SnoaL-like domain
MLHAJGEM_00311 5.56e-83 - - - M - - - Glycosyltransferase, group 2 family protein
MLHAJGEM_00312 1.37e-198 - - - M - - - Glycosyltransferase, group 2 family protein
MLHAJGEM_00313 4.04e-266 mccF - - V - - - LD-carboxypeptidase
MLHAJGEM_00314 6.74e-101 - - - K - - - Acetyltransferase (GNAT) domain
MLHAJGEM_00315 2.13e-312 - - - M ko:K07273 - ko00000 hydrolase, family 25
MLHAJGEM_00316 2.38e-233 - - - V - - - LD-carboxypeptidase
MLHAJGEM_00317 1.71e-160 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
MLHAJGEM_00318 3.99e-158 - - - P ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
MLHAJGEM_00319 2.27e-247 - - - - - - - -
MLHAJGEM_00320 6.11e-186 - - - S - - - hydrolase activity, acting on ester bonds
MLHAJGEM_00321 4.23e-268 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 FAD dependent oxidoreductase
MLHAJGEM_00322 3.28e-87 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease HI
MLHAJGEM_00323 5.04e-82 esbA - - S - - - Family of unknown function (DUF5322)
MLHAJGEM_00324 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
MLHAJGEM_00325 1.65e-97 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MLHAJGEM_00326 9.72e-225 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
MLHAJGEM_00327 1.1e-114 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MLHAJGEM_00328 4.89e-263 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarA family
MLHAJGEM_00329 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
MLHAJGEM_00330 0.0 - - - S - - - Bacterial membrane protein, YfhO
MLHAJGEM_00331 2.01e-145 - - - G - - - Phosphoglycerate mutase family
MLHAJGEM_00332 6.38e-92 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
MLHAJGEM_00335 1.38e-86 cat 2.3.1.28 - V ko:K19271 - br01600,ko00000,ko01000,ko01504 Chloramphenicol acetyltransferase
MLHAJGEM_00336 1.29e-68 cat 2.3.1.28 - V ko:K19271 - br01600,ko00000,ko01000,ko01504 Chloramphenicol acetyltransferase
MLHAJGEM_00337 8.49e-92 - - - S - - - LuxR family transcriptional regulator
MLHAJGEM_00338 1.19e-176 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2087)
MLHAJGEM_00340 4.59e-118 - - - F - - - NUDIX domain
MLHAJGEM_00341 5.3e-209 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MLHAJGEM_00342 9.28e-171 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
MLHAJGEM_00343 0.0 FbpA - - K - - - Fibronectin-binding protein
MLHAJGEM_00344 1.97e-87 - - - K - - - Transcriptional regulator
MLHAJGEM_00345 1.11e-205 - - - S - - - EDD domain protein, DegV family
MLHAJGEM_00346 2.47e-101 yjcF 3.5.4.33, 4.4.1.8 - K ko:K02348,ko:K11991,ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007,ko03016 protein acetylation
MLHAJGEM_00347 4.81e-169 - - - S - - - Protein of unknown function (DUF975)
MLHAJGEM_00348 1.57e-22 - - - - - - - -
MLHAJGEM_00349 2.37e-65 - - - - - - - -
MLHAJGEM_00350 4.87e-191 - - - C - - - Domain of unknown function (DUF4931)
MLHAJGEM_00351 6e-268 pmrB - - EGP - - - Major Facilitator Superfamily
MLHAJGEM_00353 1.33e-67 XK27_08430 - - S - - - Staphylococcal protein of unknown function (DUF960)
MLHAJGEM_00354 3.79e-166 yejC - - S - - - Protein of unknown function (DUF1003)
MLHAJGEM_00355 6.09e-176 XK27_00890 - - S ko:K08974 - ko00000 Domain of unknown function (DUF368)
MLHAJGEM_00356 2.14e-312 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
MLHAJGEM_00357 2.15e-173 - - - - - - - -
MLHAJGEM_00358 7.79e-78 - - - - - - - -
MLHAJGEM_00359 6.19e-74 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
MLHAJGEM_00360 2.23e-258 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
MLHAJGEM_00361 3.9e-289 - - - - - - - -
MLHAJGEM_00362 7.15e-165 tarI 2.7.7.40, 2.7.7.60 - I ko:K00991,ko:K21030 ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
MLHAJGEM_00363 1.47e-243 tarJ 1.1.1.137, 1.1.1.405 - E ko:K05352,ko:K21680 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
MLHAJGEM_00364 6.77e-249 tarK 2.7.8.14, 2.7.8.46, 2.7.8.47 - H ko:K18704,ko:K21592 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MLHAJGEM_00365 0.0 tarL 2.7.8.14, 2.7.8.47 - H ko:K18704 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MLHAJGEM_00366 1.57e-119 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
MLHAJGEM_00367 1.6e-93 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
MLHAJGEM_00368 3.22e-304 gshR1 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
MLHAJGEM_00369 4.65e-65 - - - - - - - -
MLHAJGEM_00370 2.78e-309 - - - M - - - Glycosyl transferase family group 2
MLHAJGEM_00371 0.0 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MLHAJGEM_00372 5.1e-204 - - - L - - - Phage integrase, N-terminal SAM-like domain
MLHAJGEM_00373 1.07e-43 - - - S - - - YozE SAM-like fold
MLHAJGEM_00374 5.31e-125 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MLHAJGEM_00375 3.8e-105 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
MLHAJGEM_00376 3.91e-216 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
MLHAJGEM_00377 3.82e-228 - - - K - - - Transcriptional regulator
MLHAJGEM_00378 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MLHAJGEM_00379 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MLHAJGEM_00380 2.4e-137 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MLHAJGEM_00381 1.04e-216 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
MLHAJGEM_00382 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MLHAJGEM_00383 6.84e-121 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MLHAJGEM_00384 1.5e-227 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family. XerC subfamily
MLHAJGEM_00385 0.0 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MLHAJGEM_00386 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MLHAJGEM_00387 1.29e-199 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
MLHAJGEM_00388 3.37e-174 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MLHAJGEM_00389 1.85e-206 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MLHAJGEM_00391 2.97e-291 XK27_05470 - - E - - - Methionine synthase
MLHAJGEM_00392 2.11e-220 cpsY - - K - - - Transcriptional regulator, LysR family
MLHAJGEM_00393 3.65e-222 - - - L ko:K07448 - ko00000,ko02048 restriction endonuclease
MLHAJGEM_00394 4.12e-159 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
MLHAJGEM_00395 4.28e-253 XK27_00915 - - C - - - Luciferase-like monooxygenase
MLHAJGEM_00396 0.0 qacA - - EGP - - - Major Facilitator
MLHAJGEM_00397 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
MLHAJGEM_00398 9.33e-48 yozE - - S - - - Belongs to the UPF0346 family
MLHAJGEM_00399 7.74e-146 ypmS - - S - - - Uncharacterized protein conserved in bacteria (DUF2140)
MLHAJGEM_00400 1.39e-207 XK27_03630 - - E - - - GDSL-like Lipase/Acylhydrolase
MLHAJGEM_00401 2.88e-189 WQ51_01275 - - S - - - EDD domain protein, DegV family
MLHAJGEM_00402 1.8e-119 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MLHAJGEM_00403 4.04e-242 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MLHAJGEM_00404 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 ABC transporter, ATP-binding protein
MLHAJGEM_00405 6.46e-109 - - - - - - - -
MLHAJGEM_00406 7.35e-291 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MLHAJGEM_00407 5.66e-185 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MLHAJGEM_00408 7.48e-192 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
MLHAJGEM_00409 2.89e-291 XK27_05225 - - S - - - Tetratricopeptide repeat protein
MLHAJGEM_00410 5.57e-55 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MLHAJGEM_00411 2.06e-314 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
MLHAJGEM_00412 1.98e-281 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
MLHAJGEM_00413 1.27e-151 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
MLHAJGEM_00414 9.99e-39 - - - M - - - Lysin motif
MLHAJGEM_00415 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
MLHAJGEM_00416 4.23e-246 - - - S - - - Helix-turn-helix domain
MLHAJGEM_00417 1.84e-125 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MLHAJGEM_00418 2.69e-167 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
MLHAJGEM_00419 1.3e-132 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MLHAJGEM_00420 3.37e-174 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MLHAJGEM_00421 3.99e-92 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MLHAJGEM_00422 3.13e-211 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
MLHAJGEM_00423 7.94e-218 yitL - - S ko:K00243 - ko00000 S1 domain
MLHAJGEM_00424 2.51e-98 ytwI - - S - - - Protein of unknown function (DUF441)
MLHAJGEM_00425 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
MLHAJGEM_00426 8.69e-230 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MLHAJGEM_00427 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
MLHAJGEM_00428 2.02e-39 - - - S - - - Protein of unknown function (DUF2929)
MLHAJGEM_00429 0.0 clpB - - O ko:K03695 ko04213,map04213 ko00000,ko00001,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MLHAJGEM_00430 1.29e-298 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
MLHAJGEM_00431 1.54e-249 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MLHAJGEM_00432 3.4e-164 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
MLHAJGEM_00433 1.75e-295 - - - M - - - O-Antigen ligase
MLHAJGEM_00434 6.72e-146 drrB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
MLHAJGEM_00435 1.4e-211 drrA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
MLHAJGEM_00436 2.74e-112 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
MLHAJGEM_00437 0.0 pps 2.7.9.2 - H ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
MLHAJGEM_00438 7.91e-83 - - - P - - - Rhodanese Homology Domain
MLHAJGEM_00439 7.43e-119 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
MLHAJGEM_00440 1.17e-267 - - - - - - - -
MLHAJGEM_00441 8.98e-86 - - - K - - - helix_turn_helix, mercury resistance
MLHAJGEM_00442 2.72e-316 hpk2 - - T - - - Histidine kinase
MLHAJGEM_00443 7.72e-165 rrp2 - - K - - - Transcriptional regulatory protein, C terminal
MLHAJGEM_00444 2.42e-65 - - - - - - - -
MLHAJGEM_00445 1.96e-167 yidA - - K - - - Helix-turn-helix domain, rpiR family
MLHAJGEM_00446 6.86e-311 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MLHAJGEM_00447 1.37e-74 - - - - - - - -
MLHAJGEM_00448 1.98e-22 - - - - - - - -
MLHAJGEM_00449 8.38e-235 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
MLHAJGEM_00450 0.0 loxD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD linked oxidases, C-terminal domain
MLHAJGEM_00451 1.49e-63 - - - - - - - -
MLHAJGEM_00452 2.04e-158 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
MLHAJGEM_00453 1.17e-135 - - - K - - - transcriptional regulator
MLHAJGEM_00454 0.0 ydgH - - S ko:K06994 - ko00000 MMPL family
MLHAJGEM_00455 8.31e-139 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
MLHAJGEM_00456 0.0 - - - S - - - Leucine-rich repeat (LRR) protein
MLHAJGEM_00457 4.32e-294 vex3 - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
MLHAJGEM_00458 4e-155 vex2 - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
MLHAJGEM_00459 1.13e-171 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
MLHAJGEM_00460 5.19e-40 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
MLHAJGEM_00461 7.98e-80 - - - M - - - Lysin motif
MLHAJGEM_00462 5.79e-82 - - - M - - - LysM domain protein
MLHAJGEM_00463 1.41e-86 gcsH1 - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Glycine cleavage H-protein
MLHAJGEM_00464 5.01e-226 - - - - - - - -
MLHAJGEM_00465 1.62e-168 - - - - - - - -
MLHAJGEM_00466 0.0 uvrB3 3.1.12.1 - KL ko:K07464 - ko00000,ko01000,ko02048 DEAD_2
MLHAJGEM_00467 2.03e-75 - - - - - - - -
MLHAJGEM_00468 9.17e-285 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MLHAJGEM_00469 1.08e-101 - - - S ko:K02348 - ko00000 GNAT family
MLHAJGEM_00470 1.24e-99 - - - K - - - Transcriptional regulator
MLHAJGEM_00471 9.59e-288 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
MLHAJGEM_00472 6.25e-53 - - - - - - - -
MLHAJGEM_00473 2.16e-264 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MLHAJGEM_00474 5.58e-181 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MLHAJGEM_00475 3.66e-189 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MLHAJGEM_00476 8.8e-264 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MLHAJGEM_00477 3.68e-125 - - - K - - - Cupin domain
MLHAJGEM_00478 8.08e-110 - - - S - - - ASCH
MLHAJGEM_00479 1.88e-111 - - - K - - - GNAT family
MLHAJGEM_00480 2.14e-117 - - - K - - - acetyltransferase
MLHAJGEM_00481 2.06e-30 - - - - - - - -
MLHAJGEM_00482 5.05e-79 - - - K ko:K07979 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
MLHAJGEM_00483 7.53e-208 - - - V ko:K01990,ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MLHAJGEM_00484 3.69e-238 - - - - - - - -
MLHAJGEM_00485 0.0 acdH 1.1.1.1, 1.2.1.10, 1.2.1.87 - C ko:K04072,ko:K13922 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Aldehyde dehydrogenase family
MLHAJGEM_00486 8.16e-207 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
MLHAJGEM_00488 2.36e-305 xylP1 - - G - - - MFS/sugar transport protein
MLHAJGEM_00489 1.43e-170 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 prohibitin homologues
MLHAJGEM_00490 7.28e-42 - - - - - - - -
MLHAJGEM_00491 0.0 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
MLHAJGEM_00492 6.4e-54 - - - - - - - -
MLHAJGEM_00493 1.54e-123 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
MLHAJGEM_00494 2.89e-225 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MLHAJGEM_00495 1.19e-78 - - - S - - - CHY zinc finger
MLHAJGEM_00496 1.51e-143 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 NLPA lipoprotein
MLHAJGEM_00497 9.26e-157 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MLHAJGEM_00498 4.45e-116 metP_2 - - U ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MLHAJGEM_00499 1.14e-186 ykpB 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MLHAJGEM_00500 5.09e-283 mtnE - - E ko:K08969 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
MLHAJGEM_00501 1.29e-279 - - - - - - - -
MLHAJGEM_00502 8.13e-199 tagG - - U ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
MLHAJGEM_00503 9.42e-258 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
MLHAJGEM_00504 2.81e-32 - - - - - - - -
MLHAJGEM_00505 2.24e-112 - - - K - - - Transcriptional regulator PadR-like family
MLHAJGEM_00506 0.0 - - - P - - - Major Facilitator Superfamily
MLHAJGEM_00507 2.88e-306 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
MLHAJGEM_00508 5.43e-228 hicD1 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
MLHAJGEM_00509 8.95e-60 - - - - - - - -
MLHAJGEM_00510 6.06e-132 zmp1 - - O - - - Zinc-dependent metalloprotease
MLHAJGEM_00511 6.87e-153 rpiA2 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
MLHAJGEM_00512 0.0 sufI - - Q - - - Multicopper oxidase
MLHAJGEM_00513 5.34e-72 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
MLHAJGEM_00514 1.31e-124 yxkA - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
MLHAJGEM_00515 5.39e-293 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
MLHAJGEM_00516 5.89e-108 - - - K - - - Winged helix-turn-helix transcription repressor, HrcA DNA-binding
MLHAJGEM_00517 2.16e-103 - - - - - - - -
MLHAJGEM_00518 3.45e-103 accB3 - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MLHAJGEM_00519 2.47e-222 rihA 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
MLHAJGEM_00520 6.93e-207 yneD - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
MLHAJGEM_00521 7.02e-103 - 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA-DNA hybrid ribonuclease activity
MLHAJGEM_00522 0.0 proWX - - EM ko:K05845,ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MLHAJGEM_00523 4.47e-229 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MLHAJGEM_00524 0.0 gshR 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Pyridine nucleotide-disulphide oxidoreductase
MLHAJGEM_00525 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MLHAJGEM_00526 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 C-terminal domain of alpha-glycerophosphate oxidase
MLHAJGEM_00527 2.14e-174 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
MLHAJGEM_00528 0.0 - - - M - - - domain protein
MLHAJGEM_00529 2.13e-132 - - - M ko:K21493 - ko00000,ko01000,ko02048 self proteolysis
MLHAJGEM_00530 1.05e-54 - - - - - - - -
MLHAJGEM_00531 3.31e-30 - - - - - - - -
MLHAJGEM_00532 1.2e-70 - - - M - - - nuclease activity
MLHAJGEM_00534 7.35e-50 - - - - - - - -
MLHAJGEM_00535 4.05e-89 - - - S - - - Immunity protein 63
MLHAJGEM_00536 6.88e-32 - - - - - - - -
MLHAJGEM_00537 2.06e-61 - - - - - - - -
MLHAJGEM_00538 3e-69 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2316)
MLHAJGEM_00539 4.61e-204 - - - S ko:K07045 - ko00000 Amidohydrolase
MLHAJGEM_00540 4.22e-130 - - - K - - - transcriptional regulator
MLHAJGEM_00541 7.17e-232 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Peroxidase
MLHAJGEM_00542 4.16e-175 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
MLHAJGEM_00543 2.5e-164 - - - S - - - Gram-negative-bacterium-type cell wall biogenesis
MLHAJGEM_00544 2.81e-232 - - - E - - - GDSL-like Lipase/Acylhydrolase family
MLHAJGEM_00545 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 P-type ATPase
MLHAJGEM_00546 8.08e-184 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
MLHAJGEM_00547 2.34e-72 trxA3 - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Thioredoxin-like domain
MLHAJGEM_00548 2.79e-54 yrkD - - S - - - Metal-sensitive transcriptional repressor
MLHAJGEM_00549 5.83e-26 - - - - - - - -
MLHAJGEM_00550 4.1e-124 dpsB - - P - - - Belongs to the Dps family
MLHAJGEM_00551 2.98e-44 copZ - - P - - - Heavy-metal-associated domain
MLHAJGEM_00552 1.05e-151 rcfA - - K ko:K21562 - ko00000,ko03000 Transcriptional regulator, Crp Fnr family
MLHAJGEM_00553 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
MLHAJGEM_00554 5.23e-107 yoaA - - J - - - COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MLHAJGEM_00555 0.0 nox 1.6.3.4 - C ko:K17869 - ko00000,ko01000 NADH oxidase
MLHAJGEM_00556 0.0 - - - S - - - Leucine-rich repeat (LRR) protein
MLHAJGEM_00557 8.64e-112 - - - S - - - Leucine-rich repeat (LRR) protein
MLHAJGEM_00558 1.24e-233 - - - S - - - Cell surface protein
MLHAJGEM_00559 1.96e-156 - - - S - - - WxL domain surface cell wall-binding
MLHAJGEM_00560 1.21e-128 - - - S - - - WxL domain surface cell wall-binding
MLHAJGEM_00561 4.54e-59 - - - - - - - -
MLHAJGEM_00562 8.19e-134 yezE - - K ko:K16137 - ko00000,ko03000 Bacterial regulatory proteins, tetR family
MLHAJGEM_00563 1.03e-65 - - - - - - - -
MLHAJGEM_00564 1.19e-313 - - - S - - - Putative metallopeptidase domain
MLHAJGEM_00565 8.13e-283 - - - S - - - associated with various cellular activities
MLHAJGEM_00566 1.95e-140 aqpZ - - U ko:K06188 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
MLHAJGEM_00567 0.0 ubiB - - S ko:K03688 - ko00000 ABC1 family
MLHAJGEM_00568 0.0 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
MLHAJGEM_00569 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
MLHAJGEM_00570 0.0 lacA 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 -beta-galactosidase
MLHAJGEM_00571 6.72e-242 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
MLHAJGEM_00572 0.0 - 3.2.1.40 - G ko:K05989 - ko00000,ko01000 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
MLHAJGEM_00573 2.13e-295 - - - P ko:K06610 - ko00000,ko02000 Sugar (and other) transporter
MLHAJGEM_00574 0.0 ram2 3.2.1.40 - G ko:K05989 - ko00000,ko01000 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
MLHAJGEM_00575 5.06e-298 - - - P ko:K06610 - ko00000,ko02000 Major Facilitator Superfamily
MLHAJGEM_00576 1.29e-235 - - - K - - - helix_turn_helix, arabinose operon control protein
MLHAJGEM_00577 5.59e-120 fic - - D ko:K04095 - ko00000,ko03036 Fic/DOC family
MLHAJGEM_00578 9.67e-84 - - - K ko:K07726 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
MLHAJGEM_00579 1.19e-234 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
MLHAJGEM_00580 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
MLHAJGEM_00581 5.14e-245 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
MLHAJGEM_00582 4.72e-286 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MLHAJGEM_00583 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
MLHAJGEM_00584 6.68e-238 lacM 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase
MLHAJGEM_00585 0.0 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
MLHAJGEM_00586 0.0 lacP - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
MLHAJGEM_00587 3.51e-252 galM3 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
MLHAJGEM_00588 1.5e-231 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
MLHAJGEM_00589 5.16e-248 tas3 - - C ko:K19265 - ko00000,ko01000 Aldo keto reductase family protein
MLHAJGEM_00590 1.17e-84 - - - S - - - pyridoxamine 5-phosphate
MLHAJGEM_00591 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
MLHAJGEM_00592 2.04e-227 apbE3 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MLHAJGEM_00593 2.2e-173 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
MLHAJGEM_00594 3.21e-212 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MLHAJGEM_00595 4.62e-224 - - - K - - - Transcriptional regulator, LysR family
MLHAJGEM_00596 1.4e-282 - - - EGP - - - Major Facilitator Superfamily
MLHAJGEM_00597 6.96e-207 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MLHAJGEM_00598 4.7e-205 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MLHAJGEM_00599 3.32e-202 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
MLHAJGEM_00600 5.56e-212 - - - G - - - Xylose isomerase-like TIM barrel
MLHAJGEM_00601 1.73e-215 - - - K - - - Transcriptional regulator, LysR family
MLHAJGEM_00602 7.86e-263 - - - EGP - - - Major Facilitator Superfamily
MLHAJGEM_00603 2.09e-83 - - - - - - - -
MLHAJGEM_00604 1.37e-177 estA - - S - - - Putative esterase
MLHAJGEM_00605 3.68e-172 - - - K - - - UTRA domain
MLHAJGEM_00606 1.87e-316 pts29C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MLHAJGEM_00607 2.9e-209 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MLHAJGEM_00608 1.69e-202 - - - G - - - BadF/BadG/BcrA/BcrD ATPase family
MLHAJGEM_00609 1.08e-267 - - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
MLHAJGEM_00610 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MLHAJGEM_00611 0.0 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MLHAJGEM_00612 3.72e-200 bglG4 - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
MLHAJGEM_00613 5.29e-283 - - - G - - - Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MLHAJGEM_00615 1.3e-209 - - - K - - - Transcriptional regulator
MLHAJGEM_00616 2.95e-207 akr5f 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
MLHAJGEM_00617 1.42e-212 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 Oxidoreductase, aldo keto reductase family protein
MLHAJGEM_00618 5.45e-98 - - - K - - - Winged helix DNA-binding domain
MLHAJGEM_00619 2.07e-125 ycaM - - E - - - amino acid
MLHAJGEM_00620 7.25e-193 ycaM - - E - - - amino acid
MLHAJGEM_00621 2.89e-165 aroC1 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Type I 3-dehydroquinase
MLHAJGEM_00622 4.3e-44 - - - - - - - -
MLHAJGEM_00623 0.0 - - - M - - - Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
MLHAJGEM_00624 0.0 - - - M - - - Domain of unknown function (DUF5011)
MLHAJGEM_00625 2.35e-101 fld - - C ko:K03839 - ko00000 Flavodoxin
MLHAJGEM_00626 0.0 - - - - ko:K21471 - ko00000,ko01000,ko01002,ko01011 -
MLHAJGEM_00627 1.26e-130 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
MLHAJGEM_00628 1.18e-225 serA1 - - EH - - - D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
MLHAJGEM_00629 2.8e-204 - - - EG - - - EamA-like transporter family
MLHAJGEM_00630 2.4e-232 ykpB 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MLHAJGEM_00631 5.06e-196 - - - S - - - hydrolase
MLHAJGEM_00632 1.8e-105 - - - - - - - -
MLHAJGEM_00633 1.75e-156 pgm7 - - G - - - Phosphoglycerate mutase family
MLHAJGEM_00634 1.4e-181 epsV - - S - - - glycosyl transferase family 2
MLHAJGEM_00635 6.37e-169 gntR - - K ko:K03489 - ko00000,ko03000 UTRA
MLHAJGEM_00636 1.86e-64 pts20B 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
MLHAJGEM_00637 2.73e-73 celC 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose Cellobiose specific IIA subunit
MLHAJGEM_00638 0.0 pbg5 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MLHAJGEM_00639 0.0 pbg4 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MLHAJGEM_00640 9.53e-317 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
MLHAJGEM_00641 1.23e-172 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
MLHAJGEM_00642 9.76e-234 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
MLHAJGEM_00643 2.13e-152 - - - K - - - Transcriptional regulator
MLHAJGEM_00644 0.0 nadC2 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MLHAJGEM_00645 1.79e-106 yrxA - - S ko:K07105 - ko00000 3H domain
MLHAJGEM_00646 5.78e-288 - - - EGP - - - Transmembrane secretion effector
MLHAJGEM_00647 1.27e-293 - - - S - - - Sterol carrier protein domain
MLHAJGEM_00648 6.01e-270 ybhE - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
MLHAJGEM_00649 3.94e-49 XK27_01315 - - S - - - Protein of unknown function (DUF2829)
MLHAJGEM_00650 1.62e-173 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
MLHAJGEM_00651 2.26e-91 - - - FG - - - Scavenger mRNA decapping enzyme C-term binding
MLHAJGEM_00652 1.13e-132 - 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
MLHAJGEM_00653 7.16e-143 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
MLHAJGEM_00654 9.47e-37 - - - S - - - Pentapeptide repeats (8 copies)
MLHAJGEM_00655 4.65e-186 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
MLHAJGEM_00656 0.0 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
MLHAJGEM_00657 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
MLHAJGEM_00658 1.21e-69 - - - - - - - -
MLHAJGEM_00659 2.15e-151 - - - - - - - -
MLHAJGEM_00660 1.16e-110 - - - F - - - belongs to the nudix hydrolase family
MLHAJGEM_00661 6.84e-296 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
MLHAJGEM_00662 1.37e-12 - - - - - - - -
MLHAJGEM_00663 2.93e-67 - - - - - - - -
MLHAJGEM_00664 1.44e-113 - - - - - - - -
MLHAJGEM_00665 5.7e-95 gtcA - - S - - - Teichoic acid glycosylation protein
MLHAJGEM_00666 3.64e-46 - - - - - - - -
MLHAJGEM_00667 2.7e-104 usp5 - - T - - - universal stress protein
MLHAJGEM_00668 3.41e-190 - - - - - - - -
MLHAJGEM_00669 1.12e-211 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MLHAJGEM_00670 8.2e-81 - - - K - - - Transcriptional regulator, GntR family
MLHAJGEM_00671 1.94e-55 - - - - - - - -
MLHAJGEM_00672 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
MLHAJGEM_00673 2.05e-178 cysA - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MLHAJGEM_00674 1.51e-232 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 Asparaginase
MLHAJGEM_00675 6.89e-190 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
MLHAJGEM_00676 1.99e-151 cah 4.2.1.1 - P ko:K01674 ko00910,map00910 ko00000,ko00001,ko01000 Eukaryotic-type carbonic anhydrase
MLHAJGEM_00677 4.81e-188 ptp3 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
MLHAJGEM_00678 2.01e-243 lplL 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Bacterial lipoate protein ligase C-terminus
MLHAJGEM_00679 9.92e-143 - - - S - - - NADPH-dependent FMN reductase
MLHAJGEM_00680 7.9e-305 XK27_09615 1.5.1.36 - S ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 reductase
MLHAJGEM_00681 3.77e-104 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MLHAJGEM_00682 5.56e-268 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MLHAJGEM_00683 3.39e-168 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
MLHAJGEM_00684 1.17e-55 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MLHAJGEM_00685 6.91e-164 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MLHAJGEM_00686 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MLHAJGEM_00687 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MLHAJGEM_00688 4.22e-243 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
MLHAJGEM_00689 5.35e-133 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MLHAJGEM_00690 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
MLHAJGEM_00691 2.23e-279 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
MLHAJGEM_00692 3.85e-159 - - - E - - - Methionine synthase
MLHAJGEM_00693 0.0 yijG - GT2 M ko:K11936 ko02026,map02026 ko00000,ko00001,ko01000,ko01003,ko02000 Glycosyl transferase
MLHAJGEM_00694 2.62e-121 - - - - - - - -
MLHAJGEM_00695 1.7e-197 - - - T - - - EAL domain
MLHAJGEM_00696 9.1e-206 - - - GM - - - NmrA-like family
MLHAJGEM_00697 4.73e-174 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MLHAJGEM_00698 6.65e-282 glgC 2.7.7.27 - H ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MLHAJGEM_00699 2.02e-268 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
MLHAJGEM_00700 0.0 glgA 2.4.1.21 GT5 F ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
MLHAJGEM_00701 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
MLHAJGEM_00702 0.0 malZ 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31 G ko:K01187,ko:K01200 ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
MLHAJGEM_00704 2.4e-183 - - - S - - - haloacid dehalogenase-like hydrolase
MLHAJGEM_00705 1.1e-154 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
MLHAJGEM_00706 0.0 trePP 2.4.1.216, 2.4.1.8 GH65 G ko:K00691,ko:K03731 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycosyl hydrolase family 65 central catalytic domain
MLHAJGEM_00707 3.21e-104 - - - S - - - Pyridoxamine 5'-phosphate oxidase
MLHAJGEM_00708 4.37e-43 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock protein domain
MLHAJGEM_00709 2.54e-50 - - - - - - - -
MLHAJGEM_00710 2.09e-292 sip - - L - - - Belongs to the 'phage' integrase family
MLHAJGEM_00713 2.3e-12 - - - - - - - -
MLHAJGEM_00714 1.07e-39 - - - - - - - -
MLHAJGEM_00715 1.01e-185 - - - L - - - DNA replication protein
MLHAJGEM_00716 0.0 - - - S - - - Virulence-associated protein E
MLHAJGEM_00718 7.19e-94 - - - - - - - -
MLHAJGEM_00720 2.65e-70 - - - S - - - Head-tail joining protein
MLHAJGEM_00721 3.19e-85 - - - L - - - HNH endonuclease
MLHAJGEM_00722 3.15e-108 - - - L - - - overlaps another CDS with the same product name
MLHAJGEM_00723 1.02e-82 terL - - S - - - overlaps another CDS with the same product name
MLHAJGEM_00724 5.08e-305 terL - - S - - - overlaps another CDS with the same product name
MLHAJGEM_00725 0.000703 - - - - - - - -
MLHAJGEM_00726 2.62e-261 - - - S - - - Phage portal protein
MLHAJGEM_00727 3.97e-38 - - - S ko:K06904 - ko00000 Caudovirus prohead serine protease
MLHAJGEM_00728 1.2e-303 - - - S ko:K06904 - ko00000 Caudovirus prohead serine protease
MLHAJGEM_00731 9.37e-53 - - - S - - - Phage gp6-like head-tail connector protein
MLHAJGEM_00732 2.77e-77 - - - - - - - -
MLHAJGEM_00733 2.54e-42 cspA - - K ko:K03704 - ko00000,ko03000 Cold shock protein
MLHAJGEM_00734 1.28e-53 - - - - - - - -
MLHAJGEM_00736 2.22e-169 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
MLHAJGEM_00737 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MLHAJGEM_00738 3.55e-313 yycH - - S - - - YycH protein
MLHAJGEM_00739 2.91e-194 yycI - - S - - - YycH protein
MLHAJGEM_00740 1.71e-200 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
MLHAJGEM_00741 1.5e-253 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
MLHAJGEM_00742 6.08e-107 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MLHAJGEM_00743 3.46e-124 - - - K - - - Bacterial regulatory proteins, tetR family
MLHAJGEM_00744 0.0 - - - C - - - Belongs to the aldehyde dehydrogenase family
MLHAJGEM_00745 4.9e-214 - - - L - - - Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
MLHAJGEM_00746 4.72e-154 ung2 - - L - - - Uracil-DNA glycosylase
MLHAJGEM_00747 1.91e-156 pnb - - C - - - nitroreductase
MLHAJGEM_00748 4.95e-86 - 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 6-pyruvoyl tetrahydropterin synthase
MLHAJGEM_00749 1.57e-150 - - - S - - - Elongation factor G-binding protein, N-terminal
MLHAJGEM_00750 0.0 - - - C - - - FMN_bind
MLHAJGEM_00751 0.0 - - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
MLHAJGEM_00752 1.46e-204 - - - K - - - LysR family
MLHAJGEM_00753 2.49e-95 - - - C - - - FMN binding
MLHAJGEM_00754 4.48e-98 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MLHAJGEM_00755 3.03e-204 - - - S - - - KR domain
MLHAJGEM_00756 9.51e-203 adc 4.1.1.4 - Q ko:K01574 ko00072,ko00640,ko01100,map00072,map00640,map01100 ko00000,ko00001,ko00002,ko01000 Acetoacetate decarboxylase (ADC)
MLHAJGEM_00757 5.07e-157 ydgI - - C - - - Nitroreductase family
MLHAJGEM_00758 0.0 - - - QT - - - PucR C-terminal helix-turn-helix domain
MLHAJGEM_00759 2.22e-154 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
MLHAJGEM_00760 1.87e-249 pva1 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MLHAJGEM_00761 0.0 - - - S - - - Putative threonine/serine exporter
MLHAJGEM_00762 2.36e-139 ptp1 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
MLHAJGEM_00763 0.0 hpaH 1.14.14.8, 1.14.14.9 - Q ko:K00483,ko:K16901 ko00350,ko00380,ko01120,ko01220,map00350,map00380,map01120,map01220 ko00000,ko00001,ko01000 4-hydroxyphenylacetate
MLHAJGEM_00764 1.65e-106 - - - S - - - ASCH
MLHAJGEM_00765 3.06e-165 - - - F - - - glutamine amidotransferase
MLHAJGEM_00766 1.67e-220 - - - K - - - WYL domain
MLHAJGEM_00767 1.63e-152 azoR - - C ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MLHAJGEM_00768 0.0 fusA1 - - J - - - elongation factor G
MLHAJGEM_00769 3.95e-35 - - - S - - - Protein of unknown function
MLHAJGEM_00770 1.51e-108 - - - S - - - Protein of unknown function
MLHAJGEM_00771 1.74e-194 - - - EG - - - EamA-like transporter family
MLHAJGEM_00772 1.66e-246 mdt(A) - - EGP ko:K08217 - br01600,ko00000,ko01504,ko02000 Transmembrane secretion effector
MLHAJGEM_00773 2.45e-28 - - - K ko:K20373,ko:K20374 ko02024,map02024 ko00000,ko00001,ko03000 Transcriptional activator, Rgg GadR MutR family
MLHAJGEM_00774 1.55e-112 yfbM - - K - - - FR47-like protein
MLHAJGEM_00775 1.4e-162 - - - S - - - DJ-1/PfpI family
MLHAJGEM_00776 1.98e-233 - 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 nadph quinone reductase
MLHAJGEM_00777 1.02e-63 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
MLHAJGEM_00778 5.98e-302 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
MLHAJGEM_00796 1.08e-117 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
MLHAJGEM_00797 1.14e-177 yhfI - - S - - - Metallo-beta-lactamase superfamily
MLHAJGEM_00798 9.28e-89 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MLHAJGEM_00799 1.68e-168 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
MLHAJGEM_00800 1.85e-263 coiA - - S ko:K06198 - ko00000 Competence protein
MLHAJGEM_00801 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
MLHAJGEM_00802 2.24e-148 yjbH - - Q - - - Thioredoxin
MLHAJGEM_00803 9.08e-157 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
MLHAJGEM_00804 1.29e-193 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MLHAJGEM_00805 1.09e-222 yjbO 5.4.99.23 - G ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
MLHAJGEM_00806 2.51e-150 cutC - - P ko:K06201 - ko00000 Participates in the control of copper homeostasis
MLHAJGEM_00807 3.22e-246 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
MLHAJGEM_00808 2.68e-75 srlB 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
MLHAJGEM_00809 9.52e-264 XK27_05220 - - S - - - AI-2E family transporter
MLHAJGEM_00810 4.82e-55 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MLHAJGEM_00811 3.74e-206 rrmA 2.1.1.187 - H ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 Methyltransferase
MLHAJGEM_00813 2.53e-301 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
MLHAJGEM_00814 2.5e-147 - - - S ko:K07118 - ko00000 NAD(P)H-binding
MLHAJGEM_00815 1.41e-124 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MLHAJGEM_00816 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
MLHAJGEM_00817 1.43e-223 - - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
MLHAJGEM_00818 3.22e-82 - - - S - - - Protein of unknown function (DUF3397)
MLHAJGEM_00819 7.24e-101 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
MLHAJGEM_00820 2.12e-225 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MLHAJGEM_00821 7.01e-76 ftsL - - D - - - Cell division protein FtsL
MLHAJGEM_00822 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
MLHAJGEM_00823 2.81e-231 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MLHAJGEM_00824 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MLHAJGEM_00825 5e-253 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MLHAJGEM_00826 2.34e-208 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MLHAJGEM_00827 3.55e-312 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MLHAJGEM_00828 1.81e-292 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MLHAJGEM_00829 1.56e-93 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MLHAJGEM_00830 6.45e-49 ylmG - - S ko:K02221 - ko00000,ko02044 YGGT family
MLHAJGEM_00831 2.06e-187 ylmH - - S - - - S4 domain protein
MLHAJGEM_00832 6.52e-124 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
MLHAJGEM_00833 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MLHAJGEM_00834 3.46e-242 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MLHAJGEM_00835 1.43e-124 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
MLHAJGEM_00836 7.74e-47 - - - - - - - -
MLHAJGEM_00837 5.85e-158 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MLHAJGEM_00838 2.13e-277 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
MLHAJGEM_00839 4.94e-75 XK27_04120 - - S - - - Putative amino acid metabolism
MLHAJGEM_00840 3.19e-285 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MLHAJGEM_00841 9.64e-307 ktrB - - P ko:K03498 - ko00000,ko02000 Potassium uptake protein
MLHAJGEM_00842 4.64e-150 ktrA - - P ko:K03499 - ko00000,ko02000 domain protein
MLHAJGEM_00843 2.32e-05 - - - N - - - WxL domain surface cell wall-binding
MLHAJGEM_00844 4.54e-129 - - - N - - - WxL domain surface cell wall-binding
MLHAJGEM_00845 4.97e-248 - - - S - - - Bacterial protein of unknown function (DUF916)
MLHAJGEM_00846 0.0 - - - N - - - domain, Protein
MLHAJGEM_00847 2.41e-157 pgm6 - - G - - - phosphoglycerate mutase
MLHAJGEM_00848 1.02e-155 - - - S - - - repeat protein
MLHAJGEM_00849 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MLHAJGEM_00850 5.35e-220 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MLHAJGEM_00851 2.62e-168 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
MLHAJGEM_00852 2.16e-39 - - - - - - - -
MLHAJGEM_00853 5.96e-241 ytlR - - I - - - Diacylglycerol kinase catalytic domain
MLHAJGEM_00854 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MLHAJGEM_00855 4.86e-45 ykzG - - S - - - Belongs to the UPF0356 family
MLHAJGEM_00856 1.85e-110 - - - - - - - -
MLHAJGEM_00857 3.95e-132 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MLHAJGEM_00858 1.21e-268 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
MLHAJGEM_00859 6.35e-230 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Transketolase, C-terminal domain protein
MLHAJGEM_00860 2.87e-286 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MLHAJGEM_00861 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
MLHAJGEM_00862 1.24e-208 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 L-malate dehydrogenase activity
MLHAJGEM_00863 6.24e-61 yktA - - S - - - Belongs to the UPF0223 family
MLHAJGEM_00864 1.23e-177 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the inositol monophosphatase superfamily
MLHAJGEM_00865 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
MLHAJGEM_00866 1.1e-257 - - - - - - - -
MLHAJGEM_00877 3.26e-119 - 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Phosphoribosyl transferase domain
MLHAJGEM_00878 6.36e-237 - - - P ko:K06901 - ko00000,ko02000 secondary active sulfate transmembrane transporter activity
MLHAJGEM_00879 7.23e-124 - - - - - - - -
MLHAJGEM_00880 1.58e-122 - - - K - - - Acetyltransferase (GNAT) domain
MLHAJGEM_00881 1.48e-172 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
MLHAJGEM_00882 3.05e-145 - - - K - - - helix_turn_helix, arabinose operon control protein
MLHAJGEM_00883 3.42e-185 lipA - - I - - - Carboxylesterase family
MLHAJGEM_00884 5.91e-208 - - - P - - - Major Facilitator Superfamily
MLHAJGEM_00885 5.42e-142 - - - GK - - - ROK family
MLHAJGEM_00886 5.39e-292 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
MLHAJGEM_00887 2.53e-240 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
MLHAJGEM_00888 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
MLHAJGEM_00889 9.6e-217 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine S-methyltransferase
MLHAJGEM_00890 0.0 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
MLHAJGEM_00891 6.75e-157 - - - - - - - -
MLHAJGEM_00892 2.78e-273 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MLHAJGEM_00893 0.0 mdr - - EGP - - - Major Facilitator
MLHAJGEM_00894 1.65e-279 - - - N - - - Cell shape-determining protein MreB
MLHAJGEM_00895 0.0 - - - S - - - Pfam Methyltransferase
MLHAJGEM_00896 0.0 tagE2 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
MLHAJGEM_00897 0.0 tagE3 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
MLHAJGEM_00898 9.32e-40 - - - - - - - -
MLHAJGEM_00899 2.49e-121 mraW1 - - J - - - Putative rRNA methylase
MLHAJGEM_00900 3.58e-161 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
MLHAJGEM_00901 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
MLHAJGEM_00902 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
MLHAJGEM_00903 5.04e-176 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
MLHAJGEM_00904 7.45e-194 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MLHAJGEM_00905 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
MLHAJGEM_00906 2.16e-109 - - - T - - - Belongs to the universal stress protein A family
MLHAJGEM_00907 1.24e-259 ugpC 3.6.3.20 - E ko:K05816,ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the ABC transporter superfamily
MLHAJGEM_00908 2.27e-221 ugpA - - U ko:K02025,ko:K05814 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MLHAJGEM_00909 6.16e-193 ugpE - - G ko:K05815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MLHAJGEM_00910 0.0 ugpB - - G ko:K05813 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
MLHAJGEM_00911 5.45e-162 glpQ1 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
MLHAJGEM_00912 2.07e-155 dgk2 - - F - - - deoxynucleoside kinase
MLHAJGEM_00913 3.55e-72 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MLHAJGEM_00914 1.37e-313 XK27_06930 - - V ko:K01421 - ko00000 domain protein
MLHAJGEM_00916 1.16e-160 - - - V ko:K01992 - ko00000,ko00002,ko02000 Transport permease protein
MLHAJGEM_00917 3.06e-201 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
MLHAJGEM_00918 2.57e-226 - - - K ko:K01990 - ko00000,ko00002,ko02000 LytTr DNA-binding domain
MLHAJGEM_00919 2.95e-199 mrsA1 1.8.4.11 - O ko:K07304 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MLHAJGEM_00920 5.2e-85 - - - K - - - helix_turn_helix, mercury resistance
MLHAJGEM_00921 4.69e-151 - - - GM - - - NAD(P)H-binding
MLHAJGEM_00922 1.09e-203 ydeD - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MLHAJGEM_00923 2.3e-190 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
MLHAJGEM_00924 7.83e-140 - - - - - - - -
MLHAJGEM_00925 1.46e-283 pltK 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
MLHAJGEM_00926 3.14e-179 agrA - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
MLHAJGEM_00927 5.37e-74 - - - - - - - -
MLHAJGEM_00928 4.56e-78 - - - - - - - -
MLHAJGEM_00929 6.38e-148 XK27_07085 - - S ko:K07052 - ko00000 CAAX protease self-immunity
MLHAJGEM_00930 2.2e-111 ohrR - - K ko:K18906 - ko00000,ko00002,ko01504,ko03000 helix_turn_helix multiple antibiotic resistance protein
MLHAJGEM_00931 1.78e-118 - - - - - - - -
MLHAJGEM_00932 7.12e-62 - - - - - - - -
MLHAJGEM_00933 0.0 uvrA2 - - L - - - ABC transporter
MLHAJGEM_00934 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
MLHAJGEM_00935 5.31e-285 - - - M - - - Glycosyl transferases group 1
MLHAJGEM_00936 1.38e-30 - - - S - - - Protein of unknown function (DUF2929)
MLHAJGEM_00937 4.05e-64 - - - K - - - Cro/C1-type HTH DNA-binding domain
MLHAJGEM_00938 8.5e-98 tcaA - - S ko:K21463 - ko00000 response to antibiotic
MLHAJGEM_00939 1.09e-55 - - - S - - - zinc-ribbon domain
MLHAJGEM_00940 3.77e-24 - - - - - - - -
MLHAJGEM_00941 2.05e-202 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
MLHAJGEM_00942 2.51e-103 uspA3 - - T - - - universal stress protein
MLHAJGEM_00943 0.0 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Bacterial SH3 domain
MLHAJGEM_00944 4.26e-250 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
MLHAJGEM_00945 4.15e-78 - - - - - - - -
MLHAJGEM_00946 4.05e-98 - - - - - - - -
MLHAJGEM_00947 6.94e-106 - - - S - - - Protein of unknown function (DUF2798)
MLHAJGEM_00948 1.57e-71 - - - - - - - -
MLHAJGEM_00949 5.52e-62 - - - - - - - -
MLHAJGEM_00950 3.87e-262 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Cys/Met metabolism PLP-dependent enzyme
MLHAJGEM_00951 9.89e-74 ytpP - - CO - - - Thioredoxin
MLHAJGEM_00952 1.19e-186 - - - S ko:K06889 - ko00000 Dienelactone hydrolase family
MLHAJGEM_00953 2.77e-87 - - - - - - - -
MLHAJGEM_00954 0.0 spxB 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
MLHAJGEM_00955 2.31e-62 - - - - - - - -
MLHAJGEM_00956 4.31e-76 - - - - - - - -
MLHAJGEM_00958 6.23e-209 - - - - - - - -
MLHAJGEM_00959 1.4e-95 - - - K - - - Transcriptional regulator
MLHAJGEM_00960 0.0 pepF2 - - E - - - Oligopeptidase F
MLHAJGEM_00961 9.32e-223 ybcH - - D ko:K06889 - ko00000 Alpha beta
MLHAJGEM_00962 7.2e-61 - - - S - - - Enterocin A Immunity
MLHAJGEM_00963 8.34e-86 lexA - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator, GntR family
MLHAJGEM_00964 5e-162 skfE - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
MLHAJGEM_00965 6.25e-171 - - - - - - - -
MLHAJGEM_00966 9.38e-139 pncA - - Q - - - Isochorismatase family
MLHAJGEM_00967 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MLHAJGEM_00968 0.0 nhaP2 - - P ko:K03316 - ko00000 Sodium proton antiporter
MLHAJGEM_00969 2.11e-251 yhhX - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
MLHAJGEM_00970 2.89e-226 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
MLHAJGEM_00971 4.61e-147 - - - K - - - Helix-turn-helix domain, rpiR family
MLHAJGEM_00972 1.48e-201 ccpB - - K - - - lacI family
MLHAJGEM_00973 1.27e-156 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
MLHAJGEM_00974 3.31e-207 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MLHAJGEM_00975 1.23e-228 iunH1 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 nucleoside hydrolase
MLHAJGEM_00976 2.57e-128 - - - C - - - Nitroreductase family
MLHAJGEM_00977 6.04e-217 - - - S - - - Polyphosphate kinase 2 (PPK2)
MLHAJGEM_00978 5.49e-249 - - - S - - - domain, Protein
MLHAJGEM_00979 1.68e-180 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
MLHAJGEM_00980 6.65e-235 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
MLHAJGEM_00981 0.0 glpQ4 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 phosphodiesterase
MLHAJGEM_00982 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MLHAJGEM_00983 2.11e-98 yjcF - - S - - - Acetyltransferase (GNAT) domain
MLHAJGEM_00984 0.0 - - - M - - - domain protein
MLHAJGEM_00985 0.0 ydgH - - S ko:K06994 - ko00000 MMPL family
MLHAJGEM_00986 3.1e-144 - - - S - - - Protein of unknown function (DUF1211)
MLHAJGEM_00987 1.45e-46 - - - - - - - -
MLHAJGEM_00988 2.33e-237 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MLHAJGEM_00989 8.35e-256 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MLHAJGEM_00990 4.54e-126 - - - J - - - glyoxalase III activity
MLHAJGEM_00991 2.05e-189 - - - GM - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
MLHAJGEM_00992 1.12e-116 rmeB - - K - - - transcriptional regulator, MerR family
MLHAJGEM_00993 6.7e-74 - - - S - - - Domain of unknown function (DU1801)
MLHAJGEM_00994 7.28e-213 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
MLHAJGEM_00995 5.06e-281 ysaA - - V - - - RDD family
MLHAJGEM_00996 2.63e-207 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Histidinol phosphate phosphatase, HisJ
MLHAJGEM_00997 4.86e-84 - - - - - - - -
MLHAJGEM_00998 3.73e-131 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
MLHAJGEM_00999 1.71e-285 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
MLHAJGEM_01000 1.86e-132 - - - M - - - Protein of unknown function (DUF3737)
MLHAJGEM_01001 1.8e-249 - - - C - - - Aldo/keto reductase family
MLHAJGEM_01003 0.0 mdlB - - V ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MLHAJGEM_01004 0.0 mdlA - - V ko:K06148,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MLHAJGEM_01005 1.34e-315 - - - EGP - - - Major Facilitator
MLHAJGEM_01008 5.55e-316 yhgE - - V ko:K01421 - ko00000 domain protein
MLHAJGEM_01009 5.33e-142 - - - K - - - Transcriptional regulator (TetR family)
MLHAJGEM_01010 6.88e-71 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
MLHAJGEM_01011 8.21e-200 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
MLHAJGEM_01012 1.82e-130 yokL3 - - J - - - Acetyltransferase (GNAT) domain
MLHAJGEM_01013 1.24e-125 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
MLHAJGEM_01014 7.34e-168 - - - M - - - Phosphotransferase enzyme family
MLHAJGEM_01015 2.62e-281 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
MLHAJGEM_01016 0.0 ykpA - - S - - - ABC transporter, ATP-binding protein
MLHAJGEM_01017 1.57e-188 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
MLHAJGEM_01018 0.0 - - - S - - - Predicted membrane protein (DUF2207)
MLHAJGEM_01019 0.0 uvrA3 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 excinuclease ABC
MLHAJGEM_01020 4.13e-254 - - - EGP - - - Major facilitator Superfamily
MLHAJGEM_01021 2.78e-222 ropB - - K - - - Helix-turn-helix XRE-family like proteins
MLHAJGEM_01022 1.76e-298 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 Vacuole effluxer Atg22 like
MLHAJGEM_01023 0.0 npp - - S - - - type I phosphodiesterase nucleotide pyrophosphatase
MLHAJGEM_01024 1.65e-205 - - - I - - - alpha/beta hydrolase fold
MLHAJGEM_01025 4.82e-166 treR - - K ko:K03486 - ko00000,ko03000 UTRA
MLHAJGEM_01026 0.0 - - - - - - - -
MLHAJGEM_01027 2e-52 - - - S - - - Cytochrome B5
MLHAJGEM_01028 8.68e-118 pts21A - - G ko:K02755 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
MLHAJGEM_01029 1.11e-65 - - - T - - - Diguanylate cyclase, GGDEF domain
MLHAJGEM_01030 1.69e-192 - - - T - - - Diguanylate cyclase, GGDEF domain
MLHAJGEM_01031 2.82e-163 - - - T - - - Putative diguanylate phosphodiesterase
MLHAJGEM_01032 3.83e-135 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MLHAJGEM_01033 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
MLHAJGEM_01034 1.56e-108 - - - - - - - -
MLHAJGEM_01035 5.97e-96 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
MLHAJGEM_01036 6.48e-243 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MLHAJGEM_01037 1.26e-245 dus - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MLHAJGEM_01038 3.7e-30 - - - - - - - -
MLHAJGEM_01039 1.38e-131 - - - - - - - -
MLHAJGEM_01040 5.12e-212 - - - K - - - LysR substrate binding domain
MLHAJGEM_01041 3.56e-313 - - - P - - - Sodium:sulfate symporter transmembrane region
MLHAJGEM_01042 0.0 - 4.1.1.98 - H ko:K03182 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
MLHAJGEM_01043 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
MLHAJGEM_01044 7.99e-184 - - - S - - - zinc-ribbon domain
MLHAJGEM_01046 4.29e-50 - - - - - - - -
MLHAJGEM_01047 8.58e-171 - - - S ko:K06889 - ko00000 Alpha/beta hydrolase family
MLHAJGEM_01048 9.57e-231 - - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
MLHAJGEM_01049 0.0 - - - I - - - acetylesterase activity
MLHAJGEM_01050 3.45e-298 - - - M - - - Collagen binding domain
MLHAJGEM_01051 6.92e-206 yicL - - EG - - - EamA-like transporter family
MLHAJGEM_01052 3.03e-166 - - - E - - - lipolytic protein G-D-S-L family
MLHAJGEM_01053 1.39e-46 - 4.1.1.52 - S ko:K22213 - ko00000,ko01000 Amidohydrolase
MLHAJGEM_01055 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MLHAJGEM_01056 4.43e-290 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MLHAJGEM_01057 9e-184 proB 2.7.2.11 - F ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MLHAJGEM_01058 4.07e-288 yttB - - EGP - - - Major Facilitator
MLHAJGEM_01059 4.55e-315 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
MLHAJGEM_01060 3.44e-95 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
MLHAJGEM_01061 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
MLHAJGEM_01062 2.69e-47 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MLHAJGEM_01063 1.68e-108 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MLHAJGEM_01064 5.95e-65 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
MLHAJGEM_01065 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MLHAJGEM_01066 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MLHAJGEM_01067 1.03e-262 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MLHAJGEM_01068 3.82e-51 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain protein YaaA
MLHAJGEM_01069 8.19e-267 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MLHAJGEM_01070 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MLHAJGEM_01071 4.62e-20 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
MLHAJGEM_01072 3.74e-75 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MLHAJGEM_01073 1.55e-158 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MLHAJGEM_01074 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MLHAJGEM_01075 2.26e-306 - - - Q - - - Imidazolonepropionase and related amidohydrolases
MLHAJGEM_01076 2.37e-173 jag - - S ko:K06346 - ko00000 R3H domain protein
MLHAJGEM_01077 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MLHAJGEM_01078 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MLHAJGEM_01079 1.31e-143 - - - S - - - Cell surface protein
MLHAJGEM_01080 2.23e-211 - - - S - - - Bacterial protein of unknown function (DUF916)
MLHAJGEM_01082 0.0 - - - - - - - -
MLHAJGEM_01083 1.12e-140 sip3 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
MLHAJGEM_01085 0.0 pepE 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
MLHAJGEM_01086 1.67e-79 - - - K - - - Bacteriophage CI repressor helix-turn-helix domain
MLHAJGEM_01087 7.53e-165 degV1 - - S - - - DegV family
MLHAJGEM_01088 3.66e-113 - - - K - - - Acetyltransferase (GNAT) domain
MLHAJGEM_01089 3.96e-183 mhpD - - Q ko:K02509 ko00350,ko01120,map00350,map01120 ko00000,ko00001,ko01000 hydratase
MLHAJGEM_01090 6.39e-134 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
MLHAJGEM_01091 2.13e-129 padR - - K - - - Virulence activator alpha C-term
MLHAJGEM_01092 2.51e-103 - - - T - - - Universal stress protein family
MLHAJGEM_01093 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
MLHAJGEM_01094 4.04e-241 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
MLHAJGEM_01095 7.82e-210 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MLHAJGEM_01096 4.99e-88 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
MLHAJGEM_01097 2.93e-196 rbsU - - U ko:K06216 - ko00000,ko02000 ribose uptake protein RbsU
MLHAJGEM_01098 1.56e-185 srlD2 1.1.1.140 - IQ ko:K00068 ko00051,map00051 ko00000,ko00001,ko01000 NAD dependent epimerase/dehydratase family
MLHAJGEM_01099 0.0 srlM - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
MLHAJGEM_01100 3.33e-113 srlM1 - - K - - - Glucitol operon activator protein (GutM)
MLHAJGEM_01101 1.23e-129 srlA - - G ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko02000 PTS system enzyme II sorbitol-specific factor
MLHAJGEM_01102 5.04e-234 srlE 2.7.1.198 - G ko:K02782,ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Sorbitol phosphotransferase enzyme II N-terminus
MLHAJGEM_01103 6.96e-83 pts38A 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
MLHAJGEM_01104 1.38e-60 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
MLHAJGEM_01105 0.0 yicI 3.2.1.177 GH31 G ko:K01811 - ko00000,ko01000 Belongs to the glycosyl hydrolase 31 family
MLHAJGEM_01106 6.23e-198 xylR - - GK - - - ROK family
MLHAJGEM_01107 1.97e-110 - - - S - - - Pfam:DUF3816
MLHAJGEM_01108 4.93e-306 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MLHAJGEM_01109 1.27e-143 - - - - - - - -
MLHAJGEM_01110 4.39e-229 - - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
MLHAJGEM_01111 1.57e-184 - - - S - - - Peptidase_C39 like family
MLHAJGEM_01112 1.65e-34 - - - S - - - Protein of unknown function (DUF1694)
MLHAJGEM_01114 3.38e-150 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
MLHAJGEM_01115 9.79e-191 - - - KT - - - helix_turn_helix, mercury resistance
MLHAJGEM_01116 3.41e-295 gltT - - U ko:K03309,ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MLHAJGEM_01117 1.86e-123 - - - S ko:K08996 - ko00000 Protein of unknown function (DUF1440)
MLHAJGEM_01118 1.4e-239 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
MLHAJGEM_01119 1.18e-155 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MLHAJGEM_01120 2.76e-117 - - - T ko:K16923 - ko00000,ko00002,ko02000 phosphorelay sensor kinase activity
MLHAJGEM_01121 6.96e-239 iunH3 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Inosine-uridine preferring nucleoside hydrolase
MLHAJGEM_01122 3.55e-127 ywjB - - H - - - RibD C-terminal domain
MLHAJGEM_01123 1.62e-257 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MLHAJGEM_01124 9.01e-155 - - - S - - - Membrane
MLHAJGEM_01125 4.25e-199 mleP3 - - S ko:K07088 - ko00000 Membrane transport protein
MLHAJGEM_01126 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Fumarase C C-terminus
MLHAJGEM_01127 3.04e-261 - - - EGP - - - Major Facilitator Superfamily
MLHAJGEM_01128 5.08e-163 - 3.8.1.2 - S ko:K01560 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
MLHAJGEM_01129 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
MLHAJGEM_01130 2.43e-105 - - - S - - - Domain of unknown function (DUF4811)
MLHAJGEM_01131 6.27e-51 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
MLHAJGEM_01132 1.37e-27 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
MLHAJGEM_01133 1.78e-221 - - - S - - - Conserved hypothetical protein 698
MLHAJGEM_01134 2.06e-194 rlrG - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
MLHAJGEM_01135 0.0 tagE5 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Poly(Glycerol-phosphate) alpha-glucosyltransferase
MLHAJGEM_01136 0.0 tagE6 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
MLHAJGEM_01138 4.96e-88 - - - M - - - LysM domain
MLHAJGEM_01139 9.24e-119 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Methyltransferase
MLHAJGEM_01140 4.23e-215 natA - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MLHAJGEM_01141 3.91e-269 natB - - CP ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
MLHAJGEM_01142 6.27e-166 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
MLHAJGEM_01143 1.16e-72 cmd 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
MLHAJGEM_01144 4.77e-100 yphH - - S - - - Cupin domain
MLHAJGEM_01145 1.27e-103 - - - K - - - transcriptional regulator, MerR family
MLHAJGEM_01146 5.3e-302 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
MLHAJGEM_01147 0.0 ylbB - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
MLHAJGEM_01148 4.97e-156 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MLHAJGEM_01150 2.93e-151 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MLHAJGEM_01151 3.18e-141 thgA3 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
MLHAJGEM_01152 1.03e-150 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
MLHAJGEM_01153 4.86e-111 - - - - - - - -
MLHAJGEM_01154 1.08e-112 yvbK - - K - - - GNAT family
MLHAJGEM_01155 9.76e-50 - - - - - - - -
MLHAJGEM_01156 2.81e-64 - - - - - - - -
MLHAJGEM_01157 7.44e-143 pgm8 - - G - - - Histidine phosphatase superfamily (branch 1)
MLHAJGEM_01158 5.01e-82 - - - S - - - Domain of unknown function (DUF4440)
MLHAJGEM_01159 6.67e-204 - - - K - - - LysR substrate binding domain
MLHAJGEM_01160 2.53e-134 - - - GM - - - NAD(P)H-binding
MLHAJGEM_01161 2.03e-248 adh2 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
MLHAJGEM_01162 8.31e-194 - - - IQ - - - Enoyl-(Acyl carrier protein) reductase
MLHAJGEM_01163 1.28e-45 - - - - - - - -
MLHAJGEM_01164 2.1e-99 - - - T - - - Belongs to the universal stress protein A family
MLHAJGEM_01165 1.41e-122 maa 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
MLHAJGEM_01166 1.76e-162 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
MLHAJGEM_01167 5.83e-31 - - - S - - - Phage gp6-like head-tail connector protein
MLHAJGEM_01168 3.13e-17 - - - S - - - Phage head-tail joining protein
MLHAJGEM_01169 2.27e-37 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
MLHAJGEM_01170 3.55e-30 - - - S - - - Protein of unknown function (DUF806)
MLHAJGEM_01171 4.85e-94 - - - S - - - Phage tail tube protein
MLHAJGEM_01172 5.31e-19 - - - S - - - Phage tail assembly chaperone proteins, TAC
MLHAJGEM_01174 9.95e-270 - - - L - - - Phage tail tape measure protein TP901
MLHAJGEM_01175 7.12e-60 - - - M - - - tape measure
MLHAJGEM_01176 2.85e-284 - - - S - - - Phage tail protein
MLHAJGEM_01177 0.0 - - - S - - - Phage minor structural protein
MLHAJGEM_01181 3.02e-72 - - - - - - - -
MLHAJGEM_01182 2.86e-224 - - - M - - - Glycosyl hydrolases family 25
MLHAJGEM_01183 4.53e-50 - - - S - - - Haemolysin XhlA
MLHAJGEM_01185 1.48e-152 yugP - - S ko:K06973 - ko00000 Putative neutral zinc metallopeptidase
MLHAJGEM_01186 1.03e-34 - - - - - - - -
MLHAJGEM_01187 3.84e-186 WQ51_01275 - - S - - - EDD domain protein, DegV family
MLHAJGEM_01188 2.88e-164 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 LrgB-like family
MLHAJGEM_01189 9.76e-83 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 LrgA family
MLHAJGEM_01190 1.62e-134 - - - J - - - Acetyltransferase (GNAT) domain
MLHAJGEM_01191 3.23e-216 - 3.1.4.17, 3.1.4.53 - S ko:K01120,ko:K03651 ko00230,ko02025,map00230,map02025 ko00000,ko00001,ko01000 Calcineurin-like phosphoesterase
MLHAJGEM_01192 1.3e-48 - - - S - - - Phospholipase_D-nuclease N-terminal
MLHAJGEM_01193 4.31e-76 - - - S - - - Enterocin A Immunity
MLHAJGEM_01194 1.55e-114 perR - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
MLHAJGEM_01195 1.64e-135 - - - - - - - -
MLHAJGEM_01196 3.43e-303 - - - S - - - module of peptide synthetase
MLHAJGEM_01197 8.66e-130 - - - S - - - NADPH-dependent FMN reductase
MLHAJGEM_01199 1.25e-164 nth2 - - L ko:K07457 - ko00000 Base excision DNA repair protein, HhH-GPD family
MLHAJGEM_01200 0.0 pts28ABC - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MLHAJGEM_01201 7.54e-200 - - - GM - - - NmrA-like family
MLHAJGEM_01202 3.75e-103 - - - K - - - MerR family regulatory protein
MLHAJGEM_01203 2.05e-189 - - - S - - - haloacid dehalogenase-like hydrolase
MLHAJGEM_01204 1.1e-193 qorB 1.6.5.2 - GM ko:K19267 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NmrA-like family
MLHAJGEM_01205 6.26e-101 - - - - - - - -
MLHAJGEM_01206 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MLHAJGEM_01207 4.16e-151 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MLHAJGEM_01208 9.95e-165 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
MLHAJGEM_01209 1.19e-259 - - - S - - - DUF218 domain
MLHAJGEM_01210 4.31e-232 purR2 - - K ko:K02529 - ko00000,ko03000 Periplasmic binding proteins and sugar binding domain of LacI family
MLHAJGEM_01211 0.0 malL 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
MLHAJGEM_01212 0.0 pts26BCA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MLHAJGEM_01213 2.65e-199 - - - S - - - Putative adhesin
MLHAJGEM_01214 1.73e-132 - - - S - - - Protein of unknown function (DUF1700)
MLHAJGEM_01215 1.72e-69 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator
MLHAJGEM_01216 2.95e-125 - - - KT - - - response to antibiotic
MLHAJGEM_01217 3.6e-161 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
MLHAJGEM_01218 3.02e-176 - - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MLHAJGEM_01219 2.46e-157 tcyB - - E ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MLHAJGEM_01220 2.04e-165 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
MLHAJGEM_01221 6.92e-301 - - - EK - - - Aminotransferase, class I
MLHAJGEM_01222 3.36e-216 - - - K - - - LysR substrate binding domain
MLHAJGEM_01223 4.27e-188 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
MLHAJGEM_01224 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
MLHAJGEM_01225 1.66e-288 nupG - - F ko:K16323 - ko00000,ko02000 Nucleoside
MLHAJGEM_01226 6.06e-167 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
MLHAJGEM_01227 7.39e-192 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
MLHAJGEM_01228 1.01e-175 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
MLHAJGEM_01229 6.14e-202 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
MLHAJGEM_01230 1.4e-40 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
MLHAJGEM_01231 7.69e-254 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MLHAJGEM_01232 3.49e-160 - - - S - - - Protein of unknown function (DUF1129)
MLHAJGEM_01233 7.05e-270 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MLHAJGEM_01234 2.71e-207 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MLHAJGEM_01235 9.76e-161 - - - S - - - Protein of unknown function (DUF1275)
MLHAJGEM_01236 1.14e-159 vanR - - K - - - response regulator
MLHAJGEM_01237 5.61e-273 hpk31 - - T - - - Histidine kinase
MLHAJGEM_01238 3.61e-303 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
MLHAJGEM_01239 9.24e-114 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
MLHAJGEM_01240 2.05e-167 - - - E - - - branched-chain amino acid
MLHAJGEM_01241 5.93e-73 - - - S - - - branched-chain amino acid
MLHAJGEM_01242 3.75e-138 - - - S ko:K07090 - ko00000 membrane transporter protein
MLHAJGEM_01243 2.12e-72 - - - - - - - -
MLHAJGEM_01244 5.61e-98 - - - S - - - Psort location Cytoplasmic, score
MLHAJGEM_01245 2.47e-125 - - - S - - - Domain of unknown function (DUF4352)
MLHAJGEM_01246 9.58e-35 - - - S - - - Protein of unknown function (DUF4064)
MLHAJGEM_01247 3.75e-256 pkn2 - - KLT - - - Protein tyrosine kinase
MLHAJGEM_01248 2.34e-210 - - - - - - - -
MLHAJGEM_01249 7.07e-293 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
MLHAJGEM_01250 8.57e-150 - - - - - - - -
MLHAJGEM_01251 8.89e-269 xylR - - GK - - - ROK family
MLHAJGEM_01252 1.6e-233 ydbI - - K - - - AI-2E family transporter
MLHAJGEM_01253 5.06e-168 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MLHAJGEM_01254 6.79e-53 - - - - - - - -
MLHAJGEM_01256 9.59e-45 - - - L ko:K07483 - ko00000 transposase activity
MLHAJGEM_01257 6.49e-135 - - - K - - - Bacterial regulatory proteins, tetR family
MLHAJGEM_01258 2.52e-85 - - - S - - - Domain of unknown function (DUF4440)
MLHAJGEM_01259 0.0 qacA - - EGP - - - Fungal trichothecene efflux pump (TRI12)
MLHAJGEM_01260 2.18e-101 - - - GM - - - SnoaL-like domain
MLHAJGEM_01261 1.3e-137 - - - GM - - - NAD(P)H-binding
MLHAJGEM_01262 1.63e-141 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
MLHAJGEM_01263 1.68e-147 yciB - - M - - - ErfK YbiS YcfS YnhG
MLHAJGEM_01264 5.43e-112 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Bacterial SH3 domain
MLHAJGEM_01265 9.09e-260 - - - C - - - Belongs to the LDH2 MDH2 oxidoreductase family
MLHAJGEM_01267 2e-172 - - - C - - - Alcohol dehydrogenase GroES-like domain
MLHAJGEM_01268 5.4e-68 - - - K - - - HxlR-like helix-turn-helix
MLHAJGEM_01269 2.94e-45 - 4.1.1.52 - S ko:K22213 - ko00000,ko01000 Amidohydrolase
MLHAJGEM_01270 1.75e-153 - 4.1.1.52 - S ko:K22213 - ko00000,ko01000 Amidohydrolase
MLHAJGEM_01271 2.76e-185 - - - S - - - Alpha/beta hydrolase family
MLHAJGEM_01272 2.39e-102 - - - K - - - transcriptional regulator
MLHAJGEM_01273 1.34e-280 - - - S - - - Membrane
MLHAJGEM_01274 0.0 - - - G ko:K03483 - ko00000,ko03000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MLHAJGEM_01275 2.61e-64 sgaB 2.7.1.194, 2.7.1.200 - G ko:K02774,ko:K02822,ko:K03475 ko00052,ko00053,ko01100,ko01120,ko02060,map00052,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MLHAJGEM_01276 8.26e-307 ulaA - - S ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
MLHAJGEM_01277 0.0 - 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MLHAJGEM_01278 4.39e-85 - - - S - - - Protein of unknown function (DUF1093)
MLHAJGEM_01279 0.0 - - - G ko:K02752,ko:K02753,ko:K02755,ko:K02756,ko:K02757 ko00010,ko02060,map00010,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MLHAJGEM_01280 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MLHAJGEM_01281 5.82e-186 licT2 - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
MLHAJGEM_01284 7.25e-39 - - - - - - - -
MLHAJGEM_01285 9.82e-111 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
MLHAJGEM_01286 0.0 - - - S - - - MucBP domain
MLHAJGEM_01287 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
MLHAJGEM_01288 9.11e-207 - - - K - - - LysR substrate binding domain
MLHAJGEM_01289 4.54e-202 - 3.6.1.22 - L ko:K03426 ko00760,ko01100,ko04146,map00760,map01100,map04146 ko00000,ko00001,ko01000 NADH pyrophosphatase zinc ribbon domain
MLHAJGEM_01290 1.67e-166 nhaP4 - - P ko:K03316 - ko00000 Sodium proton antiporter
MLHAJGEM_01291 7.34e-117 nhaP4 - - P ko:K03316 - ko00000 Sodium proton antiporter
MLHAJGEM_01292 0.0 lepA2 - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MLHAJGEM_01293 2.8e-151 - - - K - - - Bacterial regulatory proteins, tetR family
MLHAJGEM_01294 1.05e-238 - - - NU - - - Mycoplasma protein of unknown function, DUF285
MLHAJGEM_01295 7.44e-114 - - - S - - - WxL domain surface cell wall-binding
MLHAJGEM_01296 1.52e-227 - - - S - - - Bacterial protein of unknown function (DUF916)
MLHAJGEM_01297 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
MLHAJGEM_01298 3.18e-84 - - - K - - - helix_turn_helix, mercury resistance
MLHAJGEM_01299 4.82e-190 - - - IQ - - - Enoyl-(Acyl carrier protein) reductase
MLHAJGEM_01300 4.01e-96 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
MLHAJGEM_01301 1.43e-167 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
MLHAJGEM_01302 1.12e-209 - - - GM - - - NmrA-like family
MLHAJGEM_01303 3.74e-120 - - - K - - - Bacterial regulatory proteins, tetR family
MLHAJGEM_01304 3.88e-218 fhuG - - U ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLHAJGEM_01305 1.81e-228 fhuB - - U ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLHAJGEM_01306 2.13e-186 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
MLHAJGEM_01307 1.42e-218 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
MLHAJGEM_01308 7.57e-141 - - - K - - - Bacterial regulatory proteins, tetR family
MLHAJGEM_01309 0.0 yfjF - - U - - - Sugar (and other) transporter
MLHAJGEM_01310 1.97e-229 ydhF - - S - - - Aldo keto reductase
MLHAJGEM_01311 1.27e-129 - - - S - - - Protein of unknown function (DUF1211)
MLHAJGEM_01312 1.65e-242 - 1.1.1.219 - GM ko:K00091 - ko00000,ko01000 Male sterility protein
MLHAJGEM_01313 4.38e-121 - - - K - - - Bacterial regulatory proteins, tetR family
MLHAJGEM_01314 3.81e-169 - - - S - - - KR domain
MLHAJGEM_01315 7.34e-83 - - - K - - - HxlR-like helix-turn-helix
MLHAJGEM_01316 3.16e-60 - - - S - - - Domain of unknown function (DUF1905)
MLHAJGEM_01317 0.0 - - - M - - - Glycosyl hydrolases family 25
MLHAJGEM_01318 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
MLHAJGEM_01319 1.72e-212 - - - GM - - - NmrA-like family
MLHAJGEM_01320 1.53e-128 - - - K - - - Bacterial regulatory proteins, tetR family
MLHAJGEM_01321 1.2e-280 blpH 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
MLHAJGEM_01322 8.01e-174 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
MLHAJGEM_01323 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
MLHAJGEM_01324 2.23e-145 - - - M - - - ErfK YbiS YcfS YnhG
MLHAJGEM_01325 5.78e-269 - - - EGP - - - Major Facilitator
MLHAJGEM_01326 3.25e-81 ytcD - - K - - - Transcriptional regulator, HxlR family
MLHAJGEM_01327 2.12e-153 ORF00048 - - - - - - -
MLHAJGEM_01328 1.82e-75 padR - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator PadR-like family
MLHAJGEM_01329 1.5e-149 - - - S - - - Haloacid dehalogenase-like hydrolase
MLHAJGEM_01330 7.58e-153 - - - - - - - -
MLHAJGEM_01331 9.79e-295 - - - NU - - - Mycoplasma protein of unknown function, DUF285
MLHAJGEM_01332 2.86e-81 - - - - - - - -
MLHAJGEM_01333 4.48e-130 - - - S - - - WxL domain surface cell wall-binding
MLHAJGEM_01334 1.03e-239 ynjC - - S - - - Cell surface protein
MLHAJGEM_01335 6.45e-147 - - - S - - - GyrI-like small molecule binding domain
MLHAJGEM_01336 4.8e-86 - - - S - - - Iron-sulphur cluster biosynthesis
MLHAJGEM_01337 1.27e-223 - - - C - - - Alcohol dehydrogenase GroES-like domain
MLHAJGEM_01338 7.02e-136 - - - S - - - WxL domain surface cell wall-binding
MLHAJGEM_01339 9.94e-244 - - - S - - - Cell surface protein
MLHAJGEM_01340 2.59e-97 - - - - - - - -
MLHAJGEM_01341 0.0 - - - - - - - -
MLHAJGEM_01342 6.16e-289 hpk9 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
MLHAJGEM_01343 2.81e-181 - - - K - - - Helix-turn-helix domain
MLHAJGEM_01344 0.0 aapA - - M - - - Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
MLHAJGEM_01345 1.93e-84 - - - S - - - Cupredoxin-like domain
MLHAJGEM_01346 3.65e-59 - - - S - - - Cupredoxin-like domain
MLHAJGEM_01347 0.0 copA 3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54 - P ko:K01533,ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
MLHAJGEM_01348 6.8e-272 adhC 1.1.1.90 - C ko:K00055 ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Zn-dependent alcohol dehydrogenases, class III
MLHAJGEM_01349 4.2e-286 dhaT 1.1.1.202 - C ko:K00086 ko00561,ko00640,map00561,map00640 ko00000,ko00001,ko01000 Dehydrogenase
MLHAJGEM_01350 5.83e-87 lysM - - M - - - LysM domain
MLHAJGEM_01351 0.0 - - - E - - - Amino Acid
MLHAJGEM_01352 1.74e-185 - - - K - - - Helix-turn-helix XRE-family like proteins
MLHAJGEM_01353 1.97e-92 - - - - - - - -
MLHAJGEM_01355 2.96e-209 yhxD - - IQ - - - KR domain
MLHAJGEM_01356 1.87e-289 amd - - E - - - Peptidase family M20/M25/M40
MLHAJGEM_01357 1.65e-21 - - - - - - - -
MLHAJGEM_01358 0.0 XK27_09600 - - V ko:K06147,ko:K18891 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MLHAJGEM_01359 0.0 - - - V ko:K06147,ko:K18892 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MLHAJGEM_01360 2.31e-277 - - - - - - - -
MLHAJGEM_01361 0.0 umuC - - L ko:K03502 - ko00000,ko03400 impB/mucB/samB family C-terminal domain
MLHAJGEM_01362 5.68e-97 - - - S - - - Psort location Cytoplasmic, score
MLHAJGEM_01363 1.62e-277 - - - T - - - diguanylate cyclase
MLHAJGEM_01364 1.35e-155 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Methyladenine glycosylase
MLHAJGEM_01365 8.76e-121 - - - - - - - -
MLHAJGEM_01366 2.35e-211 psaA - - P ko:K02077,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
MLHAJGEM_01367 5.3e-71 nudA - - S - - - ASCH
MLHAJGEM_01368 2.5e-49 - - - S - - - SdpI/YhfL protein family
MLHAJGEM_01369 2.43e-113 - - - M - - - Lysin motif
MLHAJGEM_01370 7.92e-94 - - - M - - - LysM domain
MLHAJGEM_01371 1.21e-98 - - - K - - - helix_turn_helix, mercury resistance
MLHAJGEM_01372 4.7e-120 - - - GM - - - Male sterility protein
MLHAJGEM_01373 2.46e-98 - - - GM - - - Male sterility protein
MLHAJGEM_01374 0.0 pbg6 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MLHAJGEM_01375 0.0 pts23C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MLHAJGEM_01376 7.47e-70 ptcB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
MLHAJGEM_01377 2.02e-85 pts23A - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
MLHAJGEM_01378 1.24e-194 - - - K - - - Helix-turn-helix domain
MLHAJGEM_01379 7.02e-73 - - - - - - - -
MLHAJGEM_01380 1.93e-205 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
MLHAJGEM_01381 2.03e-84 - - - - - - - -
MLHAJGEM_01382 1.28e-201 - - - P - - - Concanavalin A-like lectin/glucanases superfamily
MLHAJGEM_01383 0.0 - - - P - - - Concanavalin A-like lectin/glucanases superfamily
MLHAJGEM_01384 0.0 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MLHAJGEM_01385 3.21e-123 - - - P - - - Cadmium resistance transporter
MLHAJGEM_01386 1e-63 czrA - - K ko:K22043 - ko00000,ko03000 Transcriptional regulator, ArsR family
MLHAJGEM_01387 1.04e-149 - - - S - - - SNARE associated Golgi protein
MLHAJGEM_01388 7.03e-62 - - - - - - - -
MLHAJGEM_01389 1.18e-94 usp2 - - T - - - Belongs to the universal stress protein A family
MLHAJGEM_01390 0.0 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
MLHAJGEM_01391 1.39e-157 - - - K - - - Helix-turn-helix XRE-family like proteins
MLHAJGEM_01392 2.88e-106 gtcA3 - - S - - - GtrA-like protein
MLHAJGEM_01393 2.93e-169 zmp3 - - O - - - Zinc-dependent metalloprotease
MLHAJGEM_01394 1.15e-43 - - - - - - - -
MLHAJGEM_01396 1.04e-269 livJ - - E ko:K01999 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Receptor family ligand binding region
MLHAJGEM_01397 9.73e-197 livH - - U ko:K01997 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid transport system / permease component
MLHAJGEM_01398 1.88e-192 livM - - E ko:K01997,ko:K01998 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid transport system / permease component
MLHAJGEM_01399 1.28e-180 livG - - E ko:K01995 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid ATP-binding cassette transporter
MLHAJGEM_01400 2.78e-158 livF - - E ko:K01996 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter
MLHAJGEM_01401 2.33e-125 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
MLHAJGEM_01402 1.72e-135 - - - S - - - WxL domain surface cell wall-binding
MLHAJGEM_01403 8.77e-239 - - - S - - - Cell surface protein
MLHAJGEM_01404 1.35e-80 - - - - - - - -
MLHAJGEM_01405 0.0 - - - - - - - -
MLHAJGEM_01406 7.28e-218 XK27_00670 - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
MLHAJGEM_01407 2.48e-199 WQ51_06230 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
MLHAJGEM_01408 4.21e-150 - - - S ko:K05833 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
MLHAJGEM_01409 2.2e-146 nagE 2.7.1.193, 2.7.1.199, 2.7.1.208 - G ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
MLHAJGEM_01410 3.52e-278 nagE 2.7.1.193, 2.7.1.199, 2.7.1.208 - G ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
MLHAJGEM_01411 8.08e-154 ydgI3 - - C - - - Nitroreductase family
MLHAJGEM_01412 5.24e-124 - - - K - - - Transcriptional regulator, MarR family
MLHAJGEM_01413 2.36e-150 xylR - - GK - - - ROK family
MLHAJGEM_01414 6.13e-266 celD - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MLHAJGEM_01415 0.0 - 3.2.1.21 - G ko:K05350 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MLHAJGEM_01416 9e-310 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase C-terminal domain
MLHAJGEM_01417 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
MLHAJGEM_01419 2.22e-88 - - - S - - - Haloacid dehalogenase-like hydrolase
MLHAJGEM_01420 5.05e-299 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase C-terminal domain
MLHAJGEM_01421 5.98e-288 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
MLHAJGEM_01422 1.93e-43 glvR - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
MLHAJGEM_01424 4.18e-27 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
MLHAJGEM_01426 1.17e-55 ptbA 2.7.1.208 - G ko:K02755,ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
MLHAJGEM_01427 8.37e-172 - 4.1.2.17 - G ko:K01628 ko00051,ko01120,map00051,map01120 ko00000,ko00001,ko01000 Class II Aldolase and Adducin N-terminal domain
MLHAJGEM_01429 0.0 pts36C - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
MLHAJGEM_01430 2.47e-68 - 2.7.1.200 - G ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
MLHAJGEM_01431 3.71e-105 pts36A 2.7.1.200 - G ko:K02773 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MLHAJGEM_01432 2.03e-177 - - - K - - - DeoR C terminal sensor domain
MLHAJGEM_01433 1.44e-230 rhaR - - K - - - helix_turn_helix, arabinose operon control protein
MLHAJGEM_01434 6.57e-311 iolF - - P ko:K06610 - ko00000,ko02000 Sugar (and other) transporter
MLHAJGEM_01435 0.0 rhaB 2.7.1.5 - F ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
MLHAJGEM_01436 1.72e-73 rhaM 5.1.3.32 - G ko:K03534 - ko00000,ko01000 Involved in the anomeric conversion of L-rhamnose
MLHAJGEM_01437 0.0 rhaA 2.7.1.5, 5.3.1.14 - G ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 L-rhamnose isomerase (RhaA)
MLHAJGEM_01438 1.31e-210 rhaD 4.1.2.19 - H ko:K01629 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
MLHAJGEM_01439 8.36e-162 - - - S - - - Membrane
MLHAJGEM_01440 3.88e-92 yueI - - S - - - Protein of unknown function (DUF1694)
MLHAJGEM_01441 0.0 spxB 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
MLHAJGEM_01442 4.14e-94 - - - K - - - Transcriptional regulator
MLHAJGEM_01443 0.0 pox4 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
MLHAJGEM_01444 1.97e-256 lctO 1.13.12.4 - C ko:K00467,ko:K10530 ko00620,map00620 ko00000,ko00001,ko01000 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
MLHAJGEM_01446 0.0 clpL - - O ko:K04086 - ko00000,ko03110 C-terminal, D2-small domain, of ClpB protein
MLHAJGEM_01447 1.06e-85 - - - KOT ko:K07813 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01002 May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor
MLHAJGEM_01448 9.62e-19 - - - - - - - -
MLHAJGEM_01449 3.09e-211 blpH 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
MLHAJGEM_01450 2.13e-173 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
MLHAJGEM_01451 1.32e-101 nrp - - K ko:K16509 - ko00000 ArsC family
MLHAJGEM_01452 0.0 katA 1.11.1.6 - C ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 Belongs to the catalase family
MLHAJGEM_01453 1.96e-21 ytgB - - S - - - Transglycosylase associated protein
MLHAJGEM_01454 1.06e-16 - - - - - - - -
MLHAJGEM_01455 2.1e-116 - - - T - - - ECF transporter, substrate-specific component
MLHAJGEM_01456 2.43e-91 - - - S - - - Pyrimidine dimer DNA glycosylase
MLHAJGEM_01457 5.6e-292 - - - S - - - Pyridine nucleotide-disulphide oxidoreductase
MLHAJGEM_01458 3.03e-159 nanE 5.1.3.9 - G ko:K01788 ko00520,map00520 ko00000,ko00001,ko01000 Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
MLHAJGEM_01459 1.2e-262 araR - - K ko:K02103 - ko00000,ko03000 Transcriptional regulator
MLHAJGEM_01460 0.0 araP - - U - - - Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MLHAJGEM_01461 0.0 araB 2.7.1.16 - G ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 carbohydrate kinase FGGY
MLHAJGEM_01462 6.13e-175 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
MLHAJGEM_01463 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
MLHAJGEM_01464 3.25e-131 maa 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
MLHAJGEM_01469 4.3e-58 - - - L - - - Belongs to the 'phage' integrase family
MLHAJGEM_01470 0.0 - 1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31 - Q ko:K10027 ko00906,ko01100,ko01110,map00906,map01100,map01110 ko00000,ko00001,ko01000 Flavin containing amine oxidoreductase
MLHAJGEM_01471 3.47e-211 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Squalene/phytoene synthase
MLHAJGEM_01472 3.62e-215 - - - D ko:K06889 - ko00000 Alpha beta
MLHAJGEM_01473 2.88e-251 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
MLHAJGEM_01474 0.0 gshR3 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
MLHAJGEM_01475 1.02e-72 - - - S - - - Enterocin A Immunity
MLHAJGEM_01476 1.23e-313 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MLHAJGEM_01477 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MLHAJGEM_01478 1.7e-234 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MLHAJGEM_01479 4.47e-181 amiF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Oligopeptide/dipeptide transporter, C-terminal region
MLHAJGEM_01480 2.24e-242 oppD - - P ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MLHAJGEM_01481 2.95e-199 - - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MLHAJGEM_01482 0.0 amiC - - U ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MLHAJGEM_01483 0.0 amiA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
MLHAJGEM_01484 1.45e-187 ptp2 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
MLHAJGEM_01485 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MLHAJGEM_01487 1.68e-82 - - - K - - - Bacterial regulatory proteins, tetR family
MLHAJGEM_01488 3.18e-186 - - - S ko:K01421 - ko00000 ABC-2 family transporter protein
MLHAJGEM_01489 2.45e-77 - - - S - - - Protein of unknown function (DUF1211)
MLHAJGEM_01490 7.97e-108 - - - - - - - -
MLHAJGEM_01491 0.0 yhdG - - E ko:K03294 - ko00000 C-terminus of AA_permease
MLHAJGEM_01493 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
MLHAJGEM_01494 1.07e-211 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MLHAJGEM_01495 1.54e-228 ydbI - - K - - - AI-2E family transporter
MLHAJGEM_01496 5.85e-277 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
MLHAJGEM_01497 1.34e-76 - - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
MLHAJGEM_01498 1.97e-60 qacH - - U ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
MLHAJGEM_01499 2.94e-149 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
MLHAJGEM_01500 7.27e-73 - - - K ko:K21903 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
MLHAJGEM_01501 1.3e-207 czcD - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
MLHAJGEM_01502 4.47e-131 - - - K - - - Helix-turn-helix XRE-family like proteins
MLHAJGEM_01504 1.61e-29 - - - - - - - -
MLHAJGEM_01505 3.91e-124 tag2 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
MLHAJGEM_01506 3.94e-271 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 dihydropteroate synthase
MLHAJGEM_01507 3.89e-132 folQ 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Ham1 family
MLHAJGEM_01508 6.41e-316 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
MLHAJGEM_01509 1.8e-134 folE 2.7.6.3, 3.5.4.16 - F ko:K00950,ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase 1
MLHAJGEM_01510 1.59e-121 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
MLHAJGEM_01511 9.61e-84 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MLHAJGEM_01512 4.26e-109 cvpA - - S - - - Colicin V production protein
MLHAJGEM_01513 5.61e-216 - - - P ko:K02077 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
MLHAJGEM_01514 5.3e-316 - - - EGP - - - Major Facilitator
MLHAJGEM_01516 4.54e-54 - - - - - - - -
MLHAJGEM_01517 1.31e-72 ybcH - - D ko:K06889 - ko00000 Alpha beta
MLHAJGEM_01518 1.77e-282 mdtG - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
MLHAJGEM_01519 0.0 - - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
MLHAJGEM_01520 8.75e-85 - - - S - - - Protein of unknown function (DUF1398)
MLHAJGEM_01521 2.55e-65 - - - - - - - -
MLHAJGEM_01522 7.21e-35 - - - - - - - -
MLHAJGEM_01523 1.69e-312 lmrB - - U ko:K18926 - ko00000,ko00002,ko02000 Belongs to the major facilitator superfamily
MLHAJGEM_01524 2.42e-96 - - - S - - - COG NOG18757 non supervised orthologous group
MLHAJGEM_01525 4.26e-54 - - - - - - - -
MLHAJGEM_01526 4.83e-98 copR - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor CopY TcrY
MLHAJGEM_01527 0.0 copB 3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54 - P ko:K01533,ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
MLHAJGEM_01528 4.38e-243 pva2 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
MLHAJGEM_01529 7e-143 - - - S - - - VIT family
MLHAJGEM_01530 2.66e-155 - - - S - - - membrane
MLHAJGEM_01531 1.63e-203 - - - EG - - - EamA-like transporter family
MLHAJGEM_01532 2.95e-106 - - - S ko:K02348 - ko00000 GNAT family
MLHAJGEM_01533 3.57e-150 - - - GM - - - NmrA-like family
MLHAJGEM_01534 4.79e-21 - - - - - - - -
MLHAJGEM_01535 2.27e-74 - - - - - - - -
MLHAJGEM_01536 3.22e-103 hsp3 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
MLHAJGEM_01537 1.36e-112 - - - - - - - -
MLHAJGEM_01538 2.11e-82 - - - - - - - -
MLHAJGEM_01539 1.67e-273 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific adenine glycosylase
MLHAJGEM_01540 1.7e-70 - - - - - - - -
MLHAJGEM_01541 2e-86 yeaO - - S - - - Protein of unknown function, DUF488
MLHAJGEM_01542 9.97e-94 spxA - - P ko:K16509 - ko00000 ArsC family
MLHAJGEM_01543 2.71e-89 - - - K ko:K22296 - ko00000,ko03000 Winged helix DNA-binding domain
MLHAJGEM_01544 4.74e-210 - - - GM - - - NmrA-like family
MLHAJGEM_01545 1.65e-112 pgpA - - I - - - Phosphatidylglycerophosphatase A
MLHAJGEM_01546 7.1e-215 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
MLHAJGEM_01547 0.0 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
MLHAJGEM_01548 0.0 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
MLHAJGEM_01549 3.58e-36 - - - S - - - Belongs to the LOG family
MLHAJGEM_01550 7.12e-256 glmS2 - - M - - - SIS domain
MLHAJGEM_01551 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MLHAJGEM_01552 2.93e-279 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
MLHAJGEM_01553 6.45e-23 - - - S - - - YjbR
MLHAJGEM_01554 5.01e-125 - - - S - - - YjbR
MLHAJGEM_01556 0.0 cadA - - P - - - P-type ATPase
MLHAJGEM_01557 0.0 - - - U ko:K03451 - ko00000 Belongs to the BCCT transporter (TC 2.A.15) family
MLHAJGEM_01558 1.07e-156 - - - E - - - GDSL-like Lipase/Acylhydrolase family
MLHAJGEM_01559 4.29e-101 - - - - - - - -
MLHAJGEM_01560 1.46e-50 - - - S - - - Bacteriocin-protection, YdeI or OmpD-Associated
MLHAJGEM_01561 8.67e-111 - - - FG - - - HIT domain
MLHAJGEM_01562 4.99e-222 ydhF - - S - - - Aldo keto reductase
MLHAJGEM_01563 8.93e-71 - - - S - - - Pfam:DUF59
MLHAJGEM_01564 1.12e-206 pflA 1.97.1.4 - C ko:K04069 - ko00000,ko01000 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MLHAJGEM_01565 0.0 pflB 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 Pyruvate formate lyase-like
MLHAJGEM_01566 1.87e-249 - - - V - - - Beta-lactamase
MLHAJGEM_01567 1.07e-124 - - - V - - - VanZ like family
MLHAJGEM_01568 1.85e-171 - - - S - - - Phage portal protein
MLHAJGEM_01570 6.81e-267 - - - S - - - Phage Terminase
MLHAJGEM_01571 2.27e-36 - - - L - - - Phage terminase, small subunit
MLHAJGEM_01572 6.96e-54 - - - L - - - HNH endonuclease
MLHAJGEM_01583 6.18e-18 - - - - - - - -
MLHAJGEM_01585 2.42e-05 - - - - - - - -
MLHAJGEM_01586 6.67e-86 - - - L - - - Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
MLHAJGEM_01587 4.06e-84 - - - - - - - -
MLHAJGEM_01588 5.2e-64 - - - - - - - -
MLHAJGEM_01589 2.61e-206 - - - L - - - DnaD domain protein
MLHAJGEM_01591 4.11e-99 - - - - - - - -
MLHAJGEM_01592 2.21e-70 - - - - - - - -
MLHAJGEM_01594 0.000115 - - - K - - - Helix-turn-helix XRE-family like proteins
MLHAJGEM_01595 8.37e-25 - - - K - - - Cro/C1-type HTH DNA-binding domain
MLHAJGEM_01598 8.06e-53 - - - K - - - Helix-turn-helix domain
MLHAJGEM_01599 1.58e-96 - - - E - - - IrrE N-terminal-like domain
MLHAJGEM_01600 1.94e-83 - - - - - - - -
MLHAJGEM_01602 8.2e-102 - - - S - - - Domain of Unknown Function with PDB structure (DUF3862)
MLHAJGEM_01605 2.47e-15 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MLHAJGEM_01607 1.64e-48 ycnE - - S - - - Antibiotic biosynthesis monooxygenase
MLHAJGEM_01611 4.45e-11 - - - T - - - COG COG2337 Growth inhibitor
MLHAJGEM_01612 8.99e-277 int3 - - L - - - Belongs to the 'phage' integrase family
MLHAJGEM_01614 1.98e-40 - - - - - - - -
MLHAJGEM_01616 1.28e-51 - - - - - - - -
MLHAJGEM_01617 9.28e-58 - - - - - - - -
MLHAJGEM_01618 1.27e-109 - - - K - - - MarR family
MLHAJGEM_01619 0.0 - - - D - - - nuclear chromosome segregation
MLHAJGEM_01620 0.0 inlJ - - M - - - MucBP domain
MLHAJGEM_01621 6.58e-24 - - - - - - - -
MLHAJGEM_01622 3.15e-22 - - - - - - - -
MLHAJGEM_01623 6.21e-26 - - - - - - - -
MLHAJGEM_01624 9.35e-24 - - - - - - - -
MLHAJGEM_01625 9.35e-24 - - - - - - - -
MLHAJGEM_01626 9.35e-24 - - - - - - - -
MLHAJGEM_01627 2.16e-26 - - - - - - - -
MLHAJGEM_01628 4.63e-24 - - - - - - - -
MLHAJGEM_01629 0.0 - 3.6.3.44 - P ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter transmembrane region
MLHAJGEM_01630 0.0 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
MLHAJGEM_01631 0.0 - - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MLHAJGEM_01632 2.1e-33 - - - - - - - -
MLHAJGEM_01633 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
MLHAJGEM_01634 2.51e-200 glcU - - U ko:K05340 - ko00000,ko02000 sugar transport
MLHAJGEM_01635 1.83e-277 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 S-adenosylmethionine-dependent methyltransferase
MLHAJGEM_01636 0.0 yclK - - T - - - Histidine kinase
MLHAJGEM_01637 1.45e-173 yclJ - - K ko:K02483 - ko00000,ko02022 response regulator
MLHAJGEM_01638 1.22e-307 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
MLHAJGEM_01639 1.75e-50 XK27_08630 - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
MLHAJGEM_01640 1.04e-217 - - - EG - - - EamA-like transporter family
MLHAJGEM_01642 1.06e-68 - - - - - - - -
MLHAJGEM_01643 1.04e-45 - - - S - - - Protein of unknown function (DUF2922)
MLHAJGEM_01644 1.95e-41 - - - - - - - -
MLHAJGEM_01645 4.14e-132 - - - K - - - DNA-templated transcription, initiation
MLHAJGEM_01646 1.1e-167 - - - - - - - -
MLHAJGEM_01647 8.27e-181 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
MLHAJGEM_01648 6.62e-138 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
MLHAJGEM_01649 6.79e-171 lytE - - M - - - NlpC/P60 family
MLHAJGEM_01650 3.97e-64 - - - K - - - sequence-specific DNA binding
MLHAJGEM_01651 7.17e-39 - - - S - - - Antitoxin component of a toxin-antitoxin (TA) module
MLHAJGEM_01652 2.54e-94 pbpX - - V - - - Beta-lactamase
MLHAJGEM_01653 8.52e-215 hdhL 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
MLHAJGEM_01654 1.13e-257 yueF - - S - - - AI-2E family transporter
MLHAJGEM_01655 6.04e-94 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Glycerol-3-phosphate cytidylyltransferase
MLHAJGEM_01656 1.12e-289 gntP - - EG ko:K03299 - ko00000,ko02000 Gluconate
MLHAJGEM_01657 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
MLHAJGEM_01658 1.22e-218 gntZ 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
MLHAJGEM_01659 0.0 gshR3 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
MLHAJGEM_01660 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MLHAJGEM_01661 0.0 - - - - - - - -
MLHAJGEM_01662 2.03e-250 - - - M - - - MucBP domain
MLHAJGEM_01663 1.58e-207 lysR5 - - K - - - LysR substrate binding domain
MLHAJGEM_01664 1.01e-172 - - - S ko:K07090 - ko00000 membrane transporter protein
MLHAJGEM_01665 3.85e-76 ywjH - - S - - - Protein of unknown function (DUF1634)
MLHAJGEM_01666 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MLHAJGEM_01667 3.44e-210 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MLHAJGEM_01668 3.59e-241 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MLHAJGEM_01669 4.86e-258 oppD - - P ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MLHAJGEM_01670 5.67e-231 oppF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MLHAJGEM_01671 3.4e-85 - - - K - - - Winged helix DNA-binding domain
MLHAJGEM_01672 2.5e-132 - - - L - - - Integrase
MLHAJGEM_01673 0.0 clpE - - O ko:K03697 - ko00000,ko03110 Belongs to the ClpA ClpB family
MLHAJGEM_01674 5.6e-41 - - - - - - - -
MLHAJGEM_01675 1.24e-52 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
MLHAJGEM_01676 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MLHAJGEM_01677 1.41e-285 pimB 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
MLHAJGEM_01678 2.04e-254 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
MLHAJGEM_01679 1.03e-239 mprF - - I ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MLHAJGEM_01680 1.09e-290 dacA2 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
MLHAJGEM_01681 1.22e-292 araT - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
MLHAJGEM_01682 1.56e-46 ykuJ - - S - - - Protein of unknown function (DUF1797)
MLHAJGEM_01683 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MLHAJGEM_01684 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
MLHAJGEM_01685 1.62e-158 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MLHAJGEM_01686 1.71e-68 yjdJ - - S ko:K06975 - ko00000 GCN5-related N-acetyl-transferase
MLHAJGEM_01687 3.29e-127 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
MLHAJGEM_01688 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MLHAJGEM_01689 6.18e-265 yacL - - S - - - domain protein
MLHAJGEM_01690 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MLHAJGEM_01691 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
MLHAJGEM_01692 1.35e-92 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MLHAJGEM_01693 1.49e-177 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MLHAJGEM_01694 5.87e-127 yacP - - S ko:K06962 - ko00000 YacP-like NYN domain
MLHAJGEM_01695 4.21e-126 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Sigma-70 region 2
MLHAJGEM_01696 4.55e-31 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
MLHAJGEM_01697 1e-39 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MLHAJGEM_01698 1.89e-128 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
MLHAJGEM_01699 2.81e-202 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
MLHAJGEM_01700 9.76e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MLHAJGEM_01701 2.69e-158 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MLHAJGEM_01702 3.72e-105 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MLHAJGEM_01703 2.76e-74 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MLHAJGEM_01704 5.22e-229 - - - F ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
MLHAJGEM_01705 1.46e-87 - - - L - - - nuclease
MLHAJGEM_01706 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MLHAJGEM_01707 2.66e-49 - - - K - - - Helix-turn-helix domain
MLHAJGEM_01708 2.37e-140 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
MLHAJGEM_01709 2.47e-253 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MLHAJGEM_01710 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MLHAJGEM_01711 6.93e-49 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
MLHAJGEM_01712 2.73e-140 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
MLHAJGEM_01713 8.85e-118 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MLHAJGEM_01714 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MLHAJGEM_01715 2.05e-62 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MLHAJGEM_01716 5.12e-139 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MLHAJGEM_01717 1.01e-51 yaaL - - S - - - Protein of unknown function (DUF2508)
MLHAJGEM_01718 1.28e-152 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MLHAJGEM_01719 1.39e-70 yaaQ - - S - - - Cyclic-di-AMP receptor
MLHAJGEM_01720 2.33e-239 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
MLHAJGEM_01721 8.46e-77 yabA - - L - - - Involved in initiation control of chromosome replication
MLHAJGEM_01722 2.64e-213 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MLHAJGEM_01723 3.17e-191 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
MLHAJGEM_01724 4.95e-246 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
MLHAJGEM_01725 9.25e-271 phnW 2.6.1.37 - E ko:K03430 ko00440,ko01100,ko01120,map00440,map01100,map01120 ko00000,ko00001,ko01000,ko01007 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily
MLHAJGEM_01726 1.62e-186 phnX 3.11.1.1 - E ko:K05306 ko00440,ko01100,ko01120,map00440,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the HAD-like hydrolase superfamily. PhnX family
MLHAJGEM_01727 3.33e-184 phnE1 - - U ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MLHAJGEM_01728 6.51e-178 phnE2 - - U ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphonate ABC transporter permease
MLHAJGEM_01729 1.27e-174 phnC 3.6.3.28 - P ko:K02041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MLHAJGEM_01730 2.33e-240 phnD - - P ko:K02044 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphonate ABC transporter
MLHAJGEM_01731 5.62e-166 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
MLHAJGEM_01732 4.66e-131 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 Ribosomal-protein-alanine acetyltransferase
MLHAJGEM_01733 5.74e-108 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
MLHAJGEM_01734 4.41e-250 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MLHAJGEM_01735 1.5e-30 - - - L - - - PFAM Integrase catalytic region
MLHAJGEM_01736 5.13e-119 - - - S - - - ECF-type riboflavin transporter, S component
MLHAJGEM_01737 1.31e-64 - - - - - - - -
MLHAJGEM_01738 1.96e-273 yceI - - EGP ko:K08369 - ko00000,ko02000 Major Facilitator
MLHAJGEM_01739 1.1e-175 - - - F - - - NUDIX domain
MLHAJGEM_01740 2.68e-32 - - - - - - - -
MLHAJGEM_01742 1.65e-206 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
MLHAJGEM_01743 1.37e-219 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 NlpC/P60 family
MLHAJGEM_01744 5.92e-107 - - - K ko:K03719 - ko00000,ko03000,ko03036 AsnC family
MLHAJGEM_01745 2.29e-48 - - - - - - - -
MLHAJGEM_01746 1.11e-45 - - - - - - - -
MLHAJGEM_01747 2.69e-239 - - - T - - - diguanylate cyclase
MLHAJGEM_01748 0.0 - - - S - - - ABC transporter, ATP-binding protein
MLHAJGEM_01749 9.24e-140 - - - K ko:K06977 - ko00000 acetyltransferase
MLHAJGEM_01750 2.35e-106 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MLHAJGEM_01751 9.2e-62 - - - - - - - -
MLHAJGEM_01752 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.208 - G ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
MLHAJGEM_01753 1.85e-242 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MLHAJGEM_01754 5.97e-210 - - - S - - - Uncharacterised protein, DegV family COG1307
MLHAJGEM_01755 1.01e-293 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Homoserine dehydrogenase
MLHAJGEM_01756 3.52e-311 metY 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
MLHAJGEM_01757 3.77e-214 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
MLHAJGEM_01758 2.79e-226 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
MLHAJGEM_01759 6.03e-196 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
MLHAJGEM_01760 1.32e-178 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MLHAJGEM_01761 0.0 npr 1.11.1.1 - C ko:K05910 - ko00000,ko01000 NADH oxidase
MLHAJGEM_01762 2.34e-203 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 Dehydrogenase
MLHAJGEM_01763 1.01e-176 yceF - - P ko:K05794 - ko00000 membrane
MLHAJGEM_01764 4.99e-125 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
MLHAJGEM_01765 6.1e-255 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MLHAJGEM_01766 1.07e-68 hisE 3.6.1.31 - E ko:K01523 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 phosphoribosyl-ATP diphosphatase activity
MLHAJGEM_01767 6.12e-78 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MLHAJGEM_01768 1.27e-172 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MLHAJGEM_01769 6.84e-166 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MLHAJGEM_01770 2.23e-142 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MLHAJGEM_01771 2.46e-139 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
MLHAJGEM_01772 9.09e-298 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MLHAJGEM_01773 1.69e-151 hisG 2.4.2.17 - F ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
MLHAJGEM_01774 1.55e-273 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MLHAJGEM_01775 7.22e-67 - - - L - - - Belongs to the 'phage' integrase family
MLHAJGEM_01776 1.29e-118 - - - S - - - T5orf172
MLHAJGEM_01780 1.69e-48 - - - - - - - -
MLHAJGEM_01782 1.08e-27 - - - K - - - Helix-turn-helix XRE-family like proteins
MLHAJGEM_01783 5.72e-27 - - - - - - - -
MLHAJGEM_01784 8.82e-11 - - - - - - - -
MLHAJGEM_01790 1.11e-53 - - - S - - - Siphovirus Gp157
MLHAJGEM_01791 4.2e-25 - - - S - - - HNH endonuclease
MLHAJGEM_01792 3.01e-196 - - - S - - - helicase activity
MLHAJGEM_01793 4.95e-94 - - - L - - - AAA domain
MLHAJGEM_01794 3.18e-28 - - - - - - - -
MLHAJGEM_01795 4.15e-93 - - - S - - - Bifunctional DNA primase/polymerase, N-terminal
MLHAJGEM_01796 2.59e-165 - - - S ko:K06919 - ko00000 Virulence-associated protein E
MLHAJGEM_01797 2.47e-48 - - - S - - - hydrolase activity, acting on ester bonds
MLHAJGEM_01800 1.1e-56 - - - - - - - -
MLHAJGEM_01802 1.62e-44 - - - - - - - -
MLHAJGEM_01808 7.73e-13 - - - - - - - -
MLHAJGEM_01809 2.82e-212 - - - S - - - Terminase
MLHAJGEM_01810 4.07e-127 - - - S - - - Phage portal protein
MLHAJGEM_01811 2.3e-70 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Clp protease
MLHAJGEM_01812 3.19e-141 - - - S - - - Phage capsid family
MLHAJGEM_01813 2.72e-22 - - - - - - - -
MLHAJGEM_01814 6.11e-32 - - - - - - - -
MLHAJGEM_01815 1.32e-44 - - - - - - - -
MLHAJGEM_01816 4.57e-29 - - - - - - - -
MLHAJGEM_01817 1.07e-43 - - - S - - - Phage tail tube protein
MLHAJGEM_01819 5.83e-214 - - - L - - - Phage tail tape measure protein TP901
MLHAJGEM_01821 2.74e-134 - - - LM - - - DNA recombination
MLHAJGEM_01822 4.37e-27 - - - S - - - Protein of unknown function (DUF1617)
MLHAJGEM_01826 7.12e-07 - - - S - - - Bacteriophage A118-like holin, Hol118
MLHAJGEM_01827 1.49e-97 - - - M - - - Glycosyl hydrolases family 25
MLHAJGEM_01828 3.95e-130 ybcH - - D ko:K06889 - ko00000 Alpha beta
MLHAJGEM_01829 6.1e-101 - - - K - - - Domain of unknown function (DUF1836)
MLHAJGEM_01830 1.14e-110 - - - F - - - Nucleoside 2-deoxyribosyltransferase
MLHAJGEM_01831 0.0 pacL3 3.6.3.8 - P ko:K01537 - ko00000,ko01000 Cation transporter/ATPase, N-terminus
MLHAJGEM_01832 0.0 yfkN 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
MLHAJGEM_01833 2.3e-204 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
MLHAJGEM_01834 3.34e-210 yvgN - - C - - - Aldo keto reductase
MLHAJGEM_01835 3e-170 - - - S - - - Putative threonine/serine exporter
MLHAJGEM_01836 2.07e-102 - - - S - - - Threonine/Serine exporter, ThrE
MLHAJGEM_01837 3.45e-32 - - - S - - - Protein of unknown function (DUF1093)
MLHAJGEM_01838 2.69e-190 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MLHAJGEM_01839 5.94e-118 ymdB - - S - - - Macro domain protein
MLHAJGEM_01840 6.47e-124 - - - K ko:K22041 - ko00000,ko03000 transcriptional regulator
MLHAJGEM_01841 1.58e-66 - - - - - - - -
MLHAJGEM_01842 9.81e-212 - - - S - - - Protein of unknown function (DUF1002)
MLHAJGEM_01843 0.0 - - - - - - - -
MLHAJGEM_01844 1.36e-245 - - - S - - - Bacterial protein of unknown function (DUF916)
MLHAJGEM_01845 5.48e-171 - - - S - - - WxL domain surface cell wall-binding
MLHAJGEM_01846 1.63e-176 yesN - - T ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
MLHAJGEM_01847 1.79e-112 - - - K - - - Winged helix DNA-binding domain
MLHAJGEM_01848 3.81e-150 - - - K - - - Bacterial regulatory proteins, tetR family
MLHAJGEM_01849 0.0 pckA 4.1.1.49 - H ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Phosphoenolpyruvate carboxykinase
MLHAJGEM_01850 2.58e-37 - - - - - - - -
MLHAJGEM_01851 0.0 gadB 4.1.1.15, 4.1.2.27 - E ko:K01580,ko:K01634 ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940 ko00000,ko00001,ko00002,ko01000 Belongs to the group II decarboxylase family
MLHAJGEM_01852 1.44e-107 - - - M - - - PFAM NLP P60 protein
MLHAJGEM_01853 2.52e-70 - - - - - - - -
MLHAJGEM_01854 4.75e-80 - - - - - - - -
MLHAJGEM_01857 2.09e-169 - - - S ko:K07090 - ko00000 membrane transporter protein
MLHAJGEM_01858 5.73e-208 mleR - - K - - - LysR family
MLHAJGEM_01859 1.29e-148 - - - GM - - - NAD(P)H-binding
MLHAJGEM_01860 3.18e-123 - - - K - - - Acetyltransferase (GNAT) family
MLHAJGEM_01861 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
MLHAJGEM_01862 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
MLHAJGEM_01863 1.12e-216 oroP - - S ko:K09936 ko02024,map02024 ko00000,ko00001,ko02000 Putative inner membrane exporter, YdcZ
MLHAJGEM_01864 5.46e-145 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MLHAJGEM_01865 2.11e-159 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MLHAJGEM_01866 1.04e-218 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MLHAJGEM_01867 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
MLHAJGEM_01868 2.76e-271 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
MLHAJGEM_01869 2.78e-309 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MLHAJGEM_01870 1e-219 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
MLHAJGEM_01871 7.13e-123 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MLHAJGEM_01872 0.0 pucR_2 - - QT ko:K09684 - ko00000,ko03000 Purine catabolism regulatory protein-like family
MLHAJGEM_01873 3.1e-305 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
MLHAJGEM_01874 5.67e-280 pbuG - - S ko:K06901 - ko00000,ko02000 Permease family
MLHAJGEM_01875 2.38e-140 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
MLHAJGEM_01876 9.82e-55 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MLHAJGEM_01877 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MLHAJGEM_01878 0.0 ydaO - - E - - - amino acid
MLHAJGEM_01879 7.29e-247 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 transferase
MLHAJGEM_01880 6.57e-199 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
MLHAJGEM_01881 4.32e-148 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
MLHAJGEM_01882 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
MLHAJGEM_01883 3.43e-163 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
MLHAJGEM_01884 1.27e-129 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MLHAJGEM_01885 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MLHAJGEM_01886 1.69e-257 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MLHAJGEM_01887 1.28e-276 minJ - - O - - - Domain present in PSD-95, Dlg, and ZO-1/2.
MLHAJGEM_01888 1.49e-170 phoP - - K ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
MLHAJGEM_01889 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MLHAJGEM_01890 3.99e-200 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
MLHAJGEM_01891 2.22e-206 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
MLHAJGEM_01892 5.04e-200 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
MLHAJGEM_01893 9.78e-190 pstB2 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MLHAJGEM_01894 2.31e-179 pstB1 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MLHAJGEM_01895 1.55e-150 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
MLHAJGEM_01896 2.78e-65 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 positive regulation of macromolecule biosynthetic process
MLHAJGEM_01897 2.87e-71 yvlD - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
MLHAJGEM_01898 2.55e-225 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MLHAJGEM_01899 6.26e-213 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MLHAJGEM_01900 9.42e-234 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
MLHAJGEM_01901 1.32e-217 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
MLHAJGEM_01902 6.37e-160 - - - T - - - Putative diguanylate phosphodiesterase
MLHAJGEM_01903 0.0 nox - - C - - - NADH oxidase
MLHAJGEM_01904 7.45e-206 ydaJ - - G - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
MLHAJGEM_01905 3.33e-308 - - - - - - - -
MLHAJGEM_01906 3.58e-258 - - - S - - - Protein conserved in bacteria
MLHAJGEM_01907 6.44e-276 ydaM - - M - - - Glycosyl transferase family group 2
MLHAJGEM_01908 0.0 - - - S - - - Bacterial cellulose synthase subunit
MLHAJGEM_01909 3.75e-170 - - - T - - - diguanylate cyclase activity
MLHAJGEM_01910 8.65e-226 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MLHAJGEM_01911 4.31e-141 yviA - - S - - - Protein of unknown function (DUF421)
MLHAJGEM_01912 7.54e-99 - - - S - - - Protein of unknown function (DUF3290)
MLHAJGEM_01913 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
MLHAJGEM_01914 5.9e-170 - - - T - - - Putative diguanylate phosphodiesterase
MLHAJGEM_01915 0.0 nox2 - - S - - - Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
MLHAJGEM_01916 3.13e-133 aad 3.4.13.22 - E ko:K08641 ko01502,ko02020,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
MLHAJGEM_01917 5.33e-268 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 transporter
MLHAJGEM_01918 9.45e-152 yfbR - - S ko:K07023 - ko00000 HD containing hydrolase-like enzyme
MLHAJGEM_01919 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MLHAJGEM_01920 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MLHAJGEM_01921 2.21e-113 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MLHAJGEM_01922 7.5e-302 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
MLHAJGEM_01923 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
MLHAJGEM_01924 8.62e-114 - - - S - - - Short repeat of unknown function (DUF308)
MLHAJGEM_01925 1.71e-207 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
MLHAJGEM_01926 4.56e-243 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
MLHAJGEM_01927 1.21e-215 whiA - - K ko:K09762 - ko00000 May be required for sporulation
MLHAJGEM_01928 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MLHAJGEM_01929 1.55e-225 - 1.1.1.26 - CH ko:K00015 ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MLHAJGEM_01930 5.11e-133 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MLHAJGEM_01932 1.14e-311 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 Sigma-54 factor, core binding domain
MLHAJGEM_01933 5.75e-242 cggR - - K ko:K05311 - ko00000,ko03000 Putative sugar-binding domain
MLHAJGEM_01934 2.02e-245 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MLHAJGEM_01935 1.31e-285 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
MLHAJGEM_01936 7.15e-179 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MLHAJGEM_01937 0.0 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MLHAJGEM_01938 5.11e-171 - - - - - - - -
MLHAJGEM_01939 0.0 eriC - - P ko:K03281 - ko00000 chloride
MLHAJGEM_01940 1.76e-43 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
MLHAJGEM_01941 6.62e-180 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Serine aminopeptidase, S33
MLHAJGEM_01942 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MLHAJGEM_01943 2.4e-107 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MLHAJGEM_01944 0.0 - - - M - - - Domain of unknown function (DUF5011)
MLHAJGEM_01945 0.0 - - - M - - - Domain of unknown function (DUF5011)
MLHAJGEM_01946 1.12e-151 - - - M - - - Domain of unknown function (DUF5011)
MLHAJGEM_01947 0.0 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MLHAJGEM_01948 3.81e-170 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MLHAJGEM_01949 1.13e-136 - - - - - - - -
MLHAJGEM_01950 1.98e-199 ycsE - - S - - - Sucrose-6F-phosphate phosphohydrolase
MLHAJGEM_01951 1.4e-174 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MLHAJGEM_01952 1.23e-227 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
MLHAJGEM_01953 1.29e-105 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
MLHAJGEM_01954 2.52e-114 - - - J - - - Acetyltransferase (GNAT) domain
MLHAJGEM_01955 7.18e-131 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
MLHAJGEM_01956 2.53e-198 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
MLHAJGEM_01957 3.09e-213 ysjB - - S ko:K03810 - ko00000 Oxidoreductase family, NAD-binding Rossmann fold
MLHAJGEM_01958 6.24e-214 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
MLHAJGEM_01959 0.0 yvgP - - P ko:K03316 - ko00000 Sodium proton antiporter
MLHAJGEM_01960 3.07e-119 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
MLHAJGEM_01961 6.9e-157 - - - S - - - Protein of unknown function (DUF1361)
MLHAJGEM_01962 8.33e-192 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MLHAJGEM_01963 3.61e-181 ybbR - - S - - - YbbR-like protein
MLHAJGEM_01964 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MLHAJGEM_01965 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MLHAJGEM_01966 1.82e-157 - - - T - - - EAL domain
MLHAJGEM_01967 9.79e-191 - 3.1.3.23 - S ko:K07757 - ko00000,ko01000 Sucrose-6F-phosphate phosphohydrolase
MLHAJGEM_01968 4.22e-136 - - - K - - - Bacterial regulatory proteins, tetR family
MLHAJGEM_01969 1.2e-262 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
MLHAJGEM_01970 3.38e-70 - - - - - - - -
MLHAJGEM_01971 2.49e-95 - - - - - - - -
MLHAJGEM_01972 1.66e-167 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
MLHAJGEM_01973 3.51e-197 - - - G ko:K08217 - br01600,ko00000,ko01504,ko02000 Transmembrane secretion effector
MLHAJGEM_01974 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MLHAJGEM_01975 3.86e-49 - - - - - - - -
MLHAJGEM_01976 4.05e-120 - - - - - - - -
MLHAJGEM_01978 5.45e-94 spx1 - - P ko:K16509 - ko00000 ArsC family
MLHAJGEM_01979 3.19e-45 - - - - - - - -
MLHAJGEM_01980 1.2e-116 - - - V - - - VanZ like family
MLHAJGEM_01981 2.14e-314 - - - EGP - - - Major Facilitator
MLHAJGEM_01982 4.45e-226 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
MLHAJGEM_01983 0.0 ppk 2.7.4.1 - P ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MLHAJGEM_01984 0.0 ppx3 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
MLHAJGEM_01985 7.8e-196 licD - - M ko:K07271 - ko00000,ko01000 LicD family
MLHAJGEM_01986 6.16e-107 - - - K - - - Transcriptional regulator
MLHAJGEM_01987 1.36e-27 - - - - - - - -
MLHAJGEM_01988 1.79e-287 pbuG - - S ko:K06901 - ko00000,ko02000 permease
MLHAJGEM_01989 0.0 pox1 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
MLHAJGEM_01990 5.47e-198 ribC1 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
MLHAJGEM_01991 0.0 pox2 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
MLHAJGEM_01992 3.45e-231 pepR 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
MLHAJGEM_01993 1.23e-229 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MLHAJGEM_01994 0.0 oatA - - I - - - Acyltransferase
MLHAJGEM_01995 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
MLHAJGEM_01996 5.35e-73 - - - O - - - OsmC-like protein
MLHAJGEM_01997 2.2e-60 - - - - - - - -
MLHAJGEM_01998 0.0 yhdG - - E ko:K03294 - ko00000 Amino Acid
MLHAJGEM_01999 6.12e-115 - - - - - - - -
MLHAJGEM_02000 7.76e-193 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
MLHAJGEM_02001 7.48e-96 - - - F - - - Nudix hydrolase
MLHAJGEM_02002 1.48e-27 - - - - - - - -
MLHAJGEM_02003 6.02e-135 gmk2 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Guanylate kinase
MLHAJGEM_02004 2.02e-106 zur - - P ko:K02076,ko:K03711 - ko00000,ko03000 Belongs to the Fur family
MLHAJGEM_02005 8.84e-18 - 3.2.1.14 GH18 - ko:K01183 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 -
MLHAJGEM_02006 1.01e-188 - - - - - - - -
MLHAJGEM_02008 6.94e-146 gph1 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 HAD hydrolase, family IA, variant
MLHAJGEM_02009 4.57e-268 aspC 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
MLHAJGEM_02010 1.03e-217 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MLHAJGEM_02011 5.2e-54 - - - - - - - -
MLHAJGEM_02013 2.3e-172 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MLHAJGEM_02014 3.39e-190 glnH - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
MLHAJGEM_02015 3.14e-140 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MLHAJGEM_02016 1.04e-140 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MLHAJGEM_02017 4.07e-107 - - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
MLHAJGEM_02018 1.34e-197 - - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
MLHAJGEM_02019 0.0 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
MLHAJGEM_02020 1.5e-180 - 3.5.1.105 - G ko:K03478 - ko00000,ko01000 YdjC-like protein
MLHAJGEM_02021 0.0 steT - - E ko:K03294 - ko00000 amino acid
MLHAJGEM_02022 3.1e-96 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
MLHAJGEM_02023 8.87e-191 - - - S - - - Sulfite exporter TauE/SafE
MLHAJGEM_02024 3.08e-93 - - - K - - - MarR family
MLHAJGEM_02025 3.22e-269 - - - EGP - - - Major Facilitator Superfamily
MLHAJGEM_02026 2.93e-109 - - - S ko:K07090 - ko00000 membrane transporter protein
MLHAJGEM_02027 1.81e-128 - - - K - - - Bacterial regulatory proteins, tetR family
MLHAJGEM_02028 5.95e-300 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MLHAJGEM_02029 4.6e-102 rppH3 - - F - - - NUDIX domain
MLHAJGEM_02030 3.5e-64 sugE - - U ko:K11741 - ko00000,ko02000 Multidrug resistance protein
MLHAJGEM_02031 1.61e-36 - - - - - - - -
MLHAJGEM_02032 6.4e-164 pgm3 - - G - - - Phosphoglycerate mutase family
MLHAJGEM_02033 1.7e-160 gpm2 - - G - - - Phosphoglycerate mutase family
MLHAJGEM_02034 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
MLHAJGEM_02035 6.88e-226 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
MLHAJGEM_02036 2.23e-143 - - - S ko:K03975 - ko00000 SNARE associated Golgi protein
MLHAJGEM_02037 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
MLHAJGEM_02038 1.46e-211 fabK 1.3.1.9 - S ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Nitronate monooxygenase
MLHAJGEM_02039 2.03e-226 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
MLHAJGEM_02040 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
MLHAJGEM_02041 1.08e-71 - - - - - - - -
MLHAJGEM_02042 1.37e-83 - - - K - - - Helix-turn-helix domain
MLHAJGEM_02043 3.32e-142 XK27_07075 - - V ko:K07052 - ko00000 CAAX protease self-immunity
MLHAJGEM_02044 1.07e-74 - - - K - - - HxlR-like helix-turn-helix
MLHAJGEM_02045 3.88e-301 yceJ - - EGP ko:K08221 - ko00000,ko02000 transporter
MLHAJGEM_02046 8.69e-300 - - - S - - - Cysteine-rich secretory protein family
MLHAJGEM_02047 7.12e-55 - - - S - - - MORN repeat
MLHAJGEM_02048 0.0 XK27_09800 - - I - - - Acyltransferase family
MLHAJGEM_02049 1.81e-50 ydaS - - S - - - Transglycosylase associated protein
MLHAJGEM_02050 1.95e-116 - - - - - - - -
MLHAJGEM_02051 5.74e-32 - - - - - - - -
MLHAJGEM_02052 1.1e-93 asp1 - - S - - - Asp23 family, cell envelope-related function
MLHAJGEM_02053 1.04e-94 asp2 - - S - - - Asp23 family, cell envelope-related function
MLHAJGEM_02054 1.58e-109 yisK 3.7.1.5, 4.1.1.68 - Q ko:K05921,ko:K16164 ko00350,ko01100,ko01120,ko01220,map00350,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Fumarylacetoacetate (FAA) hydrolase family
MLHAJGEM_02055 1.35e-50 yisK 3.7.1.5, 4.1.1.68 - Q ko:K05921,ko:K16164 ko00350,ko01100,ko01120,ko01220,map00350,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Fumarylacetoacetate (FAA) hydrolase family
MLHAJGEM_02056 4.44e-213 yjdB - - S - - - Domain of unknown function (DUF4767)
MLHAJGEM_02057 4.46e-63 - 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
MLHAJGEM_02058 9.26e-181 ram2 3.2.1.40 - G ko:K05989 - ko00000,ko01000 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
MLHAJGEM_02059 1.77e-83 - - - S - - - Putative inner membrane protein (DUF1819)
MLHAJGEM_02060 1.15e-93 - - - S - - - Domain of unknown function (DUF1788)
MLHAJGEM_02061 0.0 - - - K - - - RNA-binding protein homologous to eukaryotic snRNP
MLHAJGEM_02062 4.86e-65 - - - K - - - RNA-binding protein homologous to eukaryotic snRNP
MLHAJGEM_02063 0.0 - - - V - - - Eco57I restriction-modification methylase
MLHAJGEM_02064 1.98e-202 - - - LV - - - Eco57I restriction-modification methylase
MLHAJGEM_02065 1.51e-189 - - - L - - - Belongs to the 'phage' integrase family
MLHAJGEM_02066 3.8e-222 - - - V - - - Type II restriction enzyme, methylase subunits
MLHAJGEM_02067 1.17e-280 - - - S - - - PglZ domain
MLHAJGEM_02068 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
MLHAJGEM_02069 0.000211 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
MLHAJGEM_02070 5.91e-101 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
MLHAJGEM_02071 4.92e-69 - - - L ko:K07483,ko:K09936 ko02024,map02024 ko00000,ko00001,ko02000 Helix-turn-helix domain
MLHAJGEM_02072 1.41e-107 - - - L - - - PFAM Integrase catalytic region
MLHAJGEM_02074 3.99e-118 XK27_09665 - - G ko:K15640 - ko00000 Phosphoglycerate mutase family
MLHAJGEM_02075 0.0 - - - M - - - MucBP domain
MLHAJGEM_02076 1.42e-08 - - - - - - - -
MLHAJGEM_02077 3.7e-53 - - - S - - - AAA domain
MLHAJGEM_02078 4.18e-38 - - - S - - - AAA domain
MLHAJGEM_02079 1.24e-178 - - - K - - - sequence-specific DNA binding
MLHAJGEM_02080 3.12e-123 - - - K - - - Helix-turn-helix domain
MLHAJGEM_02081 1.37e-220 - - - K - - - Transcriptional regulator
MLHAJGEM_02082 0.0 - - - C - - - FMN_bind
MLHAJGEM_02084 1.34e-198 thrB 2.7.1.39 - F ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MLHAJGEM_02085 1.71e-302 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
MLHAJGEM_02086 3.09e-106 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
MLHAJGEM_02087 0.0 tex - - K ko:K06959 - ko00000 Tex-like protein N-terminal domain protein
MLHAJGEM_02088 6.3e-95 - - - - ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 -
MLHAJGEM_02089 0.0 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
MLHAJGEM_02090 5.27e-197 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MLHAJGEM_02091 0.0 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MLHAJGEM_02092 8.06e-177 tagA 2.4.1.187 GT26 F ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
MLHAJGEM_02093 5.41e-160 yvoA_2 - - K ko:K03710 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
MLHAJGEM_02094 2.92e-280 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
MLHAJGEM_02095 2.18e-174 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MLHAJGEM_02096 1.06e-195 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
MLHAJGEM_02097 1.59e-247 ysdE - - P - - - Citrate transporter
MLHAJGEM_02098 1.08e-212 pphA 3.1.3.16 - T ko:K07313 - ko00000,ko01000 Calcineurin-like phosphoesterase
MLHAJGEM_02099 1.38e-71 - - - S - - - Cupin domain
MLHAJGEM_02100 9.02e-66 - - - S - - - Cupin 2, conserved barrel domain protein
MLHAJGEM_02104 1.01e-192 - - - S - - - Calcineurin-like phosphoesterase
MLHAJGEM_02105 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
MLHAJGEM_02107 7.69e-275 araT2 - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
MLHAJGEM_02108 0.0 gabR - - K ko:K00375 - ko00000,ko03000 Bacterial regulatory proteins, gntR family
MLHAJGEM_02109 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MLHAJGEM_02110 4.71e-74 - - - S - - - SdpI/YhfL protein family
MLHAJGEM_02111 2.19e-220 - - - C - - - Zinc-binding dehydrogenase
MLHAJGEM_02112 2.84e-82 - - - K - - - helix_turn_helix, mercury resistance
MLHAJGEM_02113 1.6e-268 yttB - - EGP - - - Major Facilitator
MLHAJGEM_02114 0.0 nhaP3 - - P ko:K03316 - ko00000 Sodium proton antiporter
MLHAJGEM_02115 1.18e-114 nrdI - - F ko:K03647 - ko00000 Belongs to the NrdI family
MLHAJGEM_02116 0.0 yhdP - - S - - - Transporter associated domain
MLHAJGEM_02117 2.97e-76 - - - - - - - -
MLHAJGEM_02118 2.61e-96 hsp2 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
MLHAJGEM_02119 8.96e-79 - - - - - - - -
MLHAJGEM_02120 1.7e-118 - - - K - - - Domain of unknown function (DUF1836)
MLHAJGEM_02121 8.05e-179 rrp8 - - K - - - LytTr DNA-binding domain
MLHAJGEM_02122 4.65e-149 yagB - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
MLHAJGEM_02123 1.67e-176 - - - - - - - -
MLHAJGEM_02124 4.75e-117 ybaK - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MLHAJGEM_02125 3.53e-169 - - - K - - - Transcriptional regulator
MLHAJGEM_02126 7.86e-207 - - - S - - - Putative esterase
MLHAJGEM_02127 3.46e-180 - - - S - - - Phage portal protein
MLHAJGEM_02129 0.0 terL - - S - - - overlaps another CDS with the same product name
MLHAJGEM_02130 7.16e-51 - - - L - - - Phage terminase, small subunit
MLHAJGEM_02131 2.45e-79 - - - V - - - HNH nucleases
MLHAJGEM_02133 4.79e-18 - - - - - - - -
MLHAJGEM_02134 6.49e-25 - - - - - - - -
MLHAJGEM_02135 9.31e-84 - - - S - - - Transcriptional regulator, RinA family
MLHAJGEM_02136 4.61e-25 - - - - - - - -
MLHAJGEM_02139 2.44e-22 - - - S - - - YopX protein
MLHAJGEM_02141 1.05e-22 - - - - - - - -
MLHAJGEM_02142 1.1e-16 - - - - - - - -
MLHAJGEM_02144 3.47e-210 pi346 - - L ko:K02315 - ko00000,ko03032 IstB-like ATP binding protein
MLHAJGEM_02145 6.58e-98 - - - L - - - DnaD domain protein
MLHAJGEM_02156 1.95e-86 - - - S - - - DNA binding
MLHAJGEM_02158 6.93e-48 - - - K - - - Helix-turn-helix XRE-family like proteins
MLHAJGEM_02161 1.7e-49 - - - P ko:K10716 - ko00000,ko02000 Ion transport protein
MLHAJGEM_02162 2.72e-42 - - - - - - - -
MLHAJGEM_02164 3.53e-32 - - - - - - - -
MLHAJGEM_02165 1.12e-147 zmp2 - - O - - - Zinc-dependent metalloprotease
MLHAJGEM_02166 1.11e-164 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MLHAJGEM_02167 2.86e-225 - - - EG - - - EamA-like transporter family
MLHAJGEM_02168 7.53e-215 mleP2 - - S ko:K07088 - ko00000 Transporter, auxin efflux carrier (AEC) family protein
MLHAJGEM_02169 1.32e-233 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
MLHAJGEM_02170 1.23e-177 accA1 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
MLHAJGEM_02171 6.07e-183 accD1 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MLHAJGEM_02172 1.7e-315 accC1 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase C-terminal domain
MLHAJGEM_02173 7.6e-84 accB1 - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin-requiring enzyme
MLHAJGEM_02174 2.58e-228 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MLHAJGEM_02175 1.29e-112 manX 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
MLHAJGEM_02176 2.93e-93 levD 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11194 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
MLHAJGEM_02177 0.0 levR - - K - - - Sigma-54 interaction domain
MLHAJGEM_02178 9.05e-85 manO - - S - - - Domain of unknown function (DUF956)
MLHAJGEM_02179 4.22e-216 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
MLHAJGEM_02180 4.51e-172 manM - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system
MLHAJGEM_02181 6.46e-218 manL 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
MLHAJGEM_02182 4.09e-200 - - - G - - - Peptidase_C39 like family
MLHAJGEM_02183 1.25e-300 traI 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 This gene contains a nucleotide ambiguity which may be the result of a sequencing error
MLHAJGEM_02184 1.31e-146 - - - D - - - This gene contains a nucleotide ambiguity which may be the result of a sequencing error
MLHAJGEM_02185 3.19e-257 - - - L - - - COG2826 Transposase and inactivated derivatives, IS30 family
MLHAJGEM_02186 8.8e-93 - - - S - - - Domain of unknown function (DUF305)
MLHAJGEM_02188 1.95e-45 ydaT - - - - - - -
MLHAJGEM_02189 5.75e-38 - - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
MLHAJGEM_02192 1.09e-221 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
MLHAJGEM_02193 3.17e-136 - - - L - - - Transposase and inactivated derivatives, IS30 family
MLHAJGEM_02195 1.36e-144 yhxD - - IQ - - - Enoyl-(Acyl carrier protein) reductase
MLHAJGEM_02196 7.49e-46 dcm 2.1.1.37 - H ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 C-5 cytosine-specific DNA methylase
MLHAJGEM_02197 1.44e-315 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Belongs to the DNA polymerase type-Y family
MLHAJGEM_02198 2.25e-59 - - - - - - - -
MLHAJGEM_02199 3.41e-80 - - - - - - - -
MLHAJGEM_02201 9.08e-299 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
MLHAJGEM_02202 8.73e-111 - - - IQ - - - Oxidoreductase
MLHAJGEM_02204 3.54e-101 serA1 - - EH - - - D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
MLHAJGEM_02205 5.87e-51 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain protein
MLHAJGEM_02206 1.01e-117 ydhK - - M - - - Protein of unknown function (DUF1541)
MLHAJGEM_02207 1.14e-212 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
MLHAJGEM_02208 3.73e-95 - - - L ko:K07497 - ko00000 4.5 Transposon and IS
MLHAJGEM_02210 1.79e-172 - - - D ko:K03496 - ko00000,ko03036,ko04812 CobQ CobB MinD ParA nucleotide binding domain protein
MLHAJGEM_02212 4.13e-177 repA - - S - - - Replication initiator protein A
MLHAJGEM_02213 7.9e-98 - - - Q - - - Methyltransferase
MLHAJGEM_02214 3.57e-54 - - - - - - - -
MLHAJGEM_02215 1.39e-36 - - - - - - - -
MLHAJGEM_02216 0.0 traA - - L - - - MobA MobL family protein
MLHAJGEM_02217 8.28e-67 - - - - - - - -
MLHAJGEM_02218 7.73e-132 - - - - - - - -
MLHAJGEM_02219 6.31e-68 - - - S - - - Cag pathogenicity island, type IV secretory system
MLHAJGEM_02220 1.55e-70 - - - - - - - -
MLHAJGEM_02221 1.9e-153 - - - - - - - -
MLHAJGEM_02222 6.12e-08 cps2K - - L ko:K07473 - ko00000,ko02048 bacterial-type proximal promoter sequence-specific DNA binding
MLHAJGEM_02223 2.34e-105 cps2J - - S - - - Polysaccharide biosynthesis protein
MLHAJGEM_02224 1.6e-56 - - - GM ko:K19426 - ko00000,ko01000 Polysaccharide pyruvyl transferase
MLHAJGEM_02225 1.26e-168 cps4I - - M - - - Glycosyltransferase like family 2
MLHAJGEM_02226 5.96e-218 - - - - - - - -
MLHAJGEM_02227 1.08e-159 cps4G - - M - - - Glycosyltransferase Family 4
MLHAJGEM_02228 3.24e-163 cps4F - - M - - - Glycosyl transferases group 1
MLHAJGEM_02229 2.69e-156 tuaA - - M - - - Bacterial sugar transferase
MLHAJGEM_02230 2.2e-225 cps2D 5.1.3.2, 5.1.3.25 - M ko:K01784,ko:K17947 ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130 ko00000,ko00001,ko00002,ko01000 RmlD substrate binding domain
MLHAJGEM_02231 1.67e-175 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
MLHAJGEM_02232 3.06e-156 ywqD - - D - - - Capsular exopolysaccharide family
MLHAJGEM_02233 1.66e-170 epsB - - M - - - biosynthesis protein
MLHAJGEM_02234 3.19e-45 - - - - - - - -
MLHAJGEM_02235 0.0 traI 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 This gene contains a nucleotide ambiguity which may be the result of a sequencing error
MLHAJGEM_02236 6.46e-145 tnp1216 - - L ko:K07498 - ko00000 DDE domain
MLHAJGEM_02237 0.0 cadA - - P - - - P-type ATPase
MLHAJGEM_02238 8.84e-179 - - - L - - - COG2801 Transposase and inactivated derivatives
MLHAJGEM_02239 5.71e-58 - - - L ko:K07483 - ko00000 Homeodomain-like domain
MLHAJGEM_02240 6.05e-105 tnp1216 - - L ko:K07498 - ko00000 DDE domain
MLHAJGEM_02241 1.42e-131 traI 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 This gene contains a nucleotide ambiguity which may be the result of a sequencing error
MLHAJGEM_02242 3.87e-83 - - - - - - - -
MLHAJGEM_02243 2.06e-196 - - - - - - - -
MLHAJGEM_02244 2.69e-82 - - - - - - - -
MLHAJGEM_02245 0.0 traK - - U ko:K03205 ko03070,map03070 ko00000,ko00001,ko00002,ko02044 TraM recognition site of TraD and TraG
MLHAJGEM_02246 6.36e-103 - - - - - - - -
MLHAJGEM_02247 4.2e-82 - - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
MLHAJGEM_02248 1.56e-152 - - - - - - - -
MLHAJGEM_02249 3.64e-69 - - - - - - - -
MLHAJGEM_02250 1.81e-65 - - - S - - - Cag pathogenicity island, type IV secretory system
MLHAJGEM_02251 7.2e-105 - - - - - - - -
MLHAJGEM_02253 0.0 traA - - L - - - MobA MobL family protein
MLHAJGEM_02254 1.05e-15 - - - - - - - -
MLHAJGEM_02255 5.8e-46 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
MLHAJGEM_02256 5.81e-88 - - - L - - - Transposase
MLHAJGEM_02257 5.76e-53 - - - - - - - -
MLHAJGEM_02258 2.22e-162 - - - S - - - Fic/DOC family
MLHAJGEM_02259 4.3e-36 - - - - - - - -
MLHAJGEM_02260 1.1e-225 repA - - S - - - Replication initiator protein A
MLHAJGEM_02261 3.72e-47 - - - - - - - -
MLHAJGEM_02262 3.29e-192 - - - D ko:K03496 - ko00000,ko03036,ko04812 CobQ CobB MinD ParA nucleotide binding domain protein
MLHAJGEM_02263 4.58e-213 pepI 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
MLHAJGEM_02264 9.06e-180 XK27_08125 - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
MLHAJGEM_02265 2.38e-99 - - - - - - - -
MLHAJGEM_02266 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
MLHAJGEM_02267 5.9e-181 - - - - - - - -
MLHAJGEM_02268 4.07e-05 - - - - - - - -
MLHAJGEM_02269 1.57e-145 ant1 2.7.7.47 - H ko:K00984 - ko00000,ko01000,ko01504 Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
MLHAJGEM_02271 1.67e-54 - - - - - - - -
MLHAJGEM_02272 4.29e-166 - - - P ko:K02006 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MLHAJGEM_02273 9.79e-192 - - - P ko:K02008 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
MLHAJGEM_02274 2.14e-234 cbiM - - P ko:K02007 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PDGLE domain
MLHAJGEM_02275 5.54e-104 rcfB - - K - - - Crp-like helix-turn-helix domain
MLHAJGEM_02276 3.54e-105 - - - K - - - Transcriptional regulator
MLHAJGEM_02277 4.71e-149 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MLHAJGEM_02278 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
MLHAJGEM_02279 3.39e-255 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
MLHAJGEM_02280 0.0 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
MLHAJGEM_02281 8.53e-287 - - - L - - - DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MLHAJGEM_02282 9.05e-55 - - - - - - - -
MLHAJGEM_02283 4.95e-44 - - - L - - - leucine-zipper of insertion element IS481
MLHAJGEM_02284 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
MLHAJGEM_02285 1.58e-207 rluD2 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
MLHAJGEM_02286 8.41e-67 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
MLHAJGEM_02287 8.34e-179 - - - S - - - NADPH-dependent FMN reductase
MLHAJGEM_02288 3.91e-244 - - - - - - - -
MLHAJGEM_02289 5.67e-279 yibE - - S - - - overlaps another CDS with the same product name
MLHAJGEM_02290 8.44e-163 yibF - - S - - - overlaps another CDS with the same product name
MLHAJGEM_02291 1.17e-130 - - - K - - - FR47-like protein
MLHAJGEM_02292 1.5e-156 gpm5 - - G - - - Phosphoglycerate mutase family
MLHAJGEM_02293 3.33e-64 - - - - - - - -
MLHAJGEM_02294 1.72e-245 - - - I - - - alpha/beta hydrolase fold
MLHAJGEM_02295 0.0 xylP2 - - G - - - symporter
MLHAJGEM_02296 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MLHAJGEM_02297 1.2e-281 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Amino acid kinase family
MLHAJGEM_02298 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
MLHAJGEM_02299 2.41e-66 azlD - - S - - - Branched-chain amino acid transport protein (AzlD)
MLHAJGEM_02300 1.66e-154 azlC - - E - - - branched-chain amino acid
MLHAJGEM_02301 1.75e-47 - - - K - - - MerR HTH family regulatory protein
MLHAJGEM_02302 5.99e-136 - - - - - - - -
MLHAJGEM_02303 2.72e-152 - - - S - - - Domain of unknown function (DUF4811)
MLHAJGEM_02304 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
MLHAJGEM_02305 7.79e-112 - - - K - - - MerR HTH family regulatory protein
MLHAJGEM_02306 1.36e-77 - - - - - - - -
MLHAJGEM_02307 1.7e-154 mntR - - K ko:K03709 - ko00000,ko03000 iron dependent repressor
MLHAJGEM_02308 1.78e-42 cspC - - K ko:K03704 - ko00000,ko03000 Cold shock protein
MLHAJGEM_02309 1.54e-167 - - - S - - - Putative threonine/serine exporter
MLHAJGEM_02310 7.76e-100 - - - S - - - Threonine/Serine exporter, ThrE
MLHAJGEM_02311 1.92e-241 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
MLHAJGEM_02312 4.15e-153 - - - I - - - phosphatase
MLHAJGEM_02313 3.88e-198 - - - I - - - alpha/beta hydrolase fold
MLHAJGEM_02314 3.03e-129 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
MLHAJGEM_02315 1.7e-118 - - - K - - - Transcriptional regulator
MLHAJGEM_02316 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
MLHAJGEM_02317 0.0 lysP - - E ko:K03293,ko:K11733 - ko00000,ko02000 amino acid
MLHAJGEM_02318 1.29e-153 dacB 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
MLHAJGEM_02319 1.11e-148 dgk2 - - F - - - deoxynucleoside kinase
MLHAJGEM_02320 1.62e-294 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MLHAJGEM_02328 5.66e-101 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
MLHAJGEM_02329 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MLHAJGEM_02330 1.16e-140 - - - K - - - Bacterial regulatory proteins, tetR family
MLHAJGEM_02331 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MLHAJGEM_02332 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MLHAJGEM_02333 2.11e-149 comC 3.4.23.43 - NOU ko:K02236 - ko00000,ko00002,ko01000,ko02044 Bacterial Peptidase A24 N-terminal domain
MLHAJGEM_02334 4.19e-92 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MLHAJGEM_02335 1.19e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MLHAJGEM_02336 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MLHAJGEM_02337 4.46e-66 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
MLHAJGEM_02338 4.34e-145 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MLHAJGEM_02339 9.83e-141 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
MLHAJGEM_02340 2.27e-59 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MLHAJGEM_02341 6.61e-193 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MLHAJGEM_02342 1.85e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MLHAJGEM_02343 3.59e-69 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MLHAJGEM_02344 5.46e-152 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MLHAJGEM_02345 8.29e-100 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MLHAJGEM_02346 1.11e-33 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
MLHAJGEM_02347 1.96e-54 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MLHAJGEM_02348 2.98e-78 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MLHAJGEM_02349 4.1e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MLHAJGEM_02350 3.53e-123 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MLHAJGEM_02351 4.99e-88 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MLHAJGEM_02352 2.14e-123 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MLHAJGEM_02353 1.75e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MLHAJGEM_02354 5.32e-109 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MLHAJGEM_02355 8.44e-34 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
MLHAJGEM_02356 1.32e-91 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
MLHAJGEM_02357 5.95e-300 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MLHAJGEM_02358 1.84e-160 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MLHAJGEM_02359 9.87e-45 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MLHAJGEM_02360 9.65e-79 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MLHAJGEM_02361 7.71e-82 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MLHAJGEM_02362 8.91e-220 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MLHAJGEM_02363 7.76e-81 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
MLHAJGEM_02364 1.02e-233 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
MLHAJGEM_02365 1.41e-122 hepA 2.5.1.30 - S ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase component I
MLHAJGEM_02366 8.92e-111 - - - S - - - NusG domain II
MLHAJGEM_02367 0.0 ndh 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
MLHAJGEM_02368 3.19e-194 - - - S - - - FMN_bind
MLHAJGEM_02369 2.96e-285 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MLHAJGEM_02370 1.98e-197 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MLHAJGEM_02371 1.41e-211 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MLHAJGEM_02372 1.68e-184 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MLHAJGEM_02373 3.06e-194 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MLHAJGEM_02374 4.58e-103 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MLHAJGEM_02375 8.98e-86 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
MLHAJGEM_02376 3.47e-209 yitS - - S - - - Uncharacterised protein, DegV family COG1307
MLHAJGEM_02377 6.47e-231 - - - S - - - Membrane
MLHAJGEM_02378 1.06e-258 - - - C - - - Belongs to the LDH2 MDH2 oxidoreductase family
MLHAJGEM_02379 0.0 tkt2 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MLHAJGEM_02380 1.42e-212 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MLHAJGEM_02381 9.06e-233 aroF 2.5.1.54 - E ko:K03856 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 DAHP synthetase I family
MLHAJGEM_02382 1.01e-250 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MLHAJGEM_02383 0.0 - - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
MLHAJGEM_02384 1.51e-69 yitW - - S - - - Iron-sulfur cluster assembly protein
MLHAJGEM_02385 1.41e-147 - 4.2.1.2, 4.2.1.32 - C ko:K01676,ko:K03780 ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible hydration of fumarate to (S)- malate
MLHAJGEM_02386 5.21e-226 ttdA 4.2.1.32 - C ko:K03779 ko00630,map00630 ko00000,ko00001,ko01000 Fumarate hydratase (Fumerase)
MLHAJGEM_02387 7.38e-253 - - - K - - - Helix-turn-helix domain
MLHAJGEM_02388 3.16e-196 citG 2.4.2.52 - H ko:K05966 ko02020,map02020 ko00000,ko00001,ko01000 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
MLHAJGEM_02389 1.68e-169 mntB 3.6.3.35 - P ko:K02074,ko:K09820,ko:K19973 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
MLHAJGEM_02390 3.54e-180 mtsB - - U ko:K19972,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
MLHAJGEM_02391 3e-222 mntA - - P ko:K19975,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
MLHAJGEM_02392 1.18e-66 - - - - - - - -
MLHAJGEM_02393 7.56e-214 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
MLHAJGEM_02394 1.41e-265 citP - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
MLHAJGEM_02395 8.69e-230 citR - - K - - - sugar-binding domain protein
MLHAJGEM_02396 1.92e-264 mae 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme, NAD binding domain
MLHAJGEM_02397 5.31e-242 citC 6.2.1.22 - H ko:K01910 ko02020,map02020 ko00000,ko00001,ko01000 Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
MLHAJGEM_02398 8.62e-59 citD - - C ko:K01646 ko02020,map02020 ko00000,ko00001 Covalent carrier of the coenzyme of citrate lyase
MLHAJGEM_02399 2.73e-209 citE 4.1.3.34 - G ko:K01644 ko02020,map02020 ko00000,ko00001,ko01000 Belongs to the HpcH HpaI aldolase family
MLHAJGEM_02400 0.0 citF 2.8.3.10 - H ko:K01643 ko02020,map02020 ko00000,ko00001,ko01000 Citrate (pro-3S)-lyase alpha chain
MLHAJGEM_02401 1.69e-233 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
MLHAJGEM_02403 1.91e-64 - - - K - - - sequence-specific DNA binding
MLHAJGEM_02407 3.88e-20 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
MLHAJGEM_02408 4.32e-274 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
MLHAJGEM_02409 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MLHAJGEM_02410 0.0 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
MLHAJGEM_02411 8.08e-122 citX 2.7.7.61 - HI ko:K05964 ko02020,map02020 ko00000,ko00001,ko01000 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
MLHAJGEM_02412 3.73e-206 mleR2 - - K - - - LysR family transcriptional regulator
MLHAJGEM_02413 7.59e-214 mleR - - K - - - LysR family
MLHAJGEM_02414 0.0 mleS 1.1.1.38, 4.1.1.101 - C ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme
MLHAJGEM_02415 1.51e-211 mleP2 - - S ko:K07088 - ko00000 Sodium Bile acid symporter family
MLHAJGEM_02416 0.0 - - - E ko:K03294 - ko00000 Amino Acid
MLHAJGEM_02417 4.37e-128 - - - S - - - ECF transporter, substrate-specific component
MLHAJGEM_02418 6.07e-33 - - - - - - - -
MLHAJGEM_02419 0.0 - - - S ko:K06889 - ko00000 Alpha beta
MLHAJGEM_02420 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
MLHAJGEM_02421 1.57e-233 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase subunit II
MLHAJGEM_02422 0.0 cydC - - CO ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
MLHAJGEM_02423 0.0 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
MLHAJGEM_02424 1.89e-208 - - - S - - - L,D-transpeptidase catalytic domain
MLHAJGEM_02425 4.87e-234 hepT 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
MLHAJGEM_02426 8.5e-213 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
MLHAJGEM_02427 1.35e-235 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
MLHAJGEM_02428 3.41e-146 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
MLHAJGEM_02429 2.01e-134 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MLHAJGEM_02430 1.13e-120 yebE - - S - - - UPF0316 protein
MLHAJGEM_02431 1.39e-279 purK2 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MLHAJGEM_02432 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
MLHAJGEM_02433 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MLHAJGEM_02434 9.48e-263 camS - - S - - - sex pheromone
MLHAJGEM_02435 5.11e-67 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MLHAJGEM_02436 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MLHAJGEM_02437 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MLHAJGEM_02438 1.59e-242 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
MLHAJGEM_02439 0.0 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MLHAJGEM_02440 2.26e-129 yobS - - K - - - Bacterial regulatory proteins, tetR family
MLHAJGEM_02441 0.0 yfgQ - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
MLHAJGEM_02442 1.36e-304 pts13C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MLHAJGEM_02443 6.52e-183 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
MLHAJGEM_02444 1.61e-195 gntR - - K - - - rpiR family
MLHAJGEM_02445 4.68e-187 lys - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
MLHAJGEM_02446 7.34e-83 - - - S - - - Domain of unknown function (DUF4828)
MLHAJGEM_02447 6.22e-43 cspP - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
MLHAJGEM_02448 7.89e-245 mocA - - S - - - Oxidoreductase
MLHAJGEM_02449 9.46e-315 yfmL - - L - - - DEAD DEAH box helicase
MLHAJGEM_02451 3.93e-99 - - - T - - - Universal stress protein family
MLHAJGEM_02452 1.1e-313 pts14C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MLHAJGEM_02453 1.93e-210 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
MLHAJGEM_02455 7.62e-97 - - - - - - - -
MLHAJGEM_02456 1.68e-138 - - - - - - - -
MLHAJGEM_02457 1.06e-167 - - - L - - - Helix-turn-helix domain
MLHAJGEM_02458 3.8e-189 - - - L ko:K07497 - ko00000 hmm pf00665
MLHAJGEM_02459 0.0 gdhA 1.4.1.4 - E ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
MLHAJGEM_02460 2.71e-280 pbpX - - V - - - Beta-lactamase
MLHAJGEM_02461 4.75e-267 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MLHAJGEM_02462 7.42e-202 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
MLHAJGEM_02463 8.03e-169 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
MLHAJGEM_02464 6.16e-138 - - - L - - - Resolvase, N terminal domain
MLHAJGEM_02465 1.98e-150 - - - L ko:K07497 - ko00000 hmm pf00665
MLHAJGEM_02466 3.29e-232 - 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Ribonucleotide reductase, small chain
MLHAJGEM_02467 1.95e-220 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Ribonucleotide reductase, small chain
MLHAJGEM_02468 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MLHAJGEM_02469 7.07e-106 nrdI - - F ko:K03647 - ko00000 NrdI Flavodoxin like
MLHAJGEM_02470 6.32e-08 - 3.3.1.1 - H ko:K01251 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01009,ko04147 adenosylhomocysteinase activity
MLHAJGEM_02471 4.12e-79 ypgQ - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
MLHAJGEM_02472 5.26e-247 - 1.1.1.14 - C ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Zinc-binding dehydrogenase
MLHAJGEM_02473 2.4e-295 gatC - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
MLHAJGEM_02474 1.72e-59 - 2.7.1.200 - G ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
MLHAJGEM_02475 3.99e-106 - 2.7.1.200, 2.7.1.204 - G ko:K02773,ko:K20112 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MLHAJGEM_02476 3.05e-161 - - - K ko:K02444 - ko00000,ko03000 DeoR C terminal sensor domain
MLHAJGEM_02477 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
MLHAJGEM_02478 8.85e-85 - - - S - - - Cupredoxin-like domain
MLHAJGEM_02479 5.01e-61 - - - S - - - Cupredoxin-like domain
MLHAJGEM_02480 0.0 copA 3.6.3.3, 3.6.3.5, 3.6.3.54 - P ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
MLHAJGEM_02481 2.57e-06 - 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter
MLHAJGEM_02482 3.71e-88 - - - KT - - - COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLHAJGEM_02483 0.0 yclK - - T - - - Histidine kinase
MLHAJGEM_02484 5.93e-197 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MLHAJGEM_02486 4.23e-07 - - - S - - - Protein of unknown function (DUF2933)
MLHAJGEM_02487 1.23e-129 - - - M - - - Protein of unknown function (DUF3737)
MLHAJGEM_02488 1.65e-42 - - - L ko:K07483 - ko00000 Transposase and inactivated derivatives
MLHAJGEM_02489 1.67e-182 - - - U ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MLHAJGEM_02490 8.34e-194 - - - U ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MLHAJGEM_02491 7.41e-315 - - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
MLHAJGEM_02492 3.79e-272 msmK2 - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MLHAJGEM_02493 1.38e-08 - - - - - - - -
MLHAJGEM_02494 3.91e-74 - - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
MLHAJGEM_02495 5.23e-102 - - - - - - - -
MLHAJGEM_02496 0.0 traK - - U ko:K03205 ko03070,map03070 ko00000,ko00001,ko00002,ko02044 TraM recognition site of TraD and TraG
MLHAJGEM_02497 1e-78 - - - - - - - -
MLHAJGEM_02498 8.4e-199 - - - - - - - -
MLHAJGEM_02499 4.03e-85 - - - - - - - -
MLHAJGEM_02500 0.0 traI 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 This gene contains a nucleotide ambiguity which may be the result of a sequencing error
MLHAJGEM_02501 1.24e-259 - 3.3.1.1 - H ko:K01251 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01009,ko04147 adenosylhomocysteinase activity
MLHAJGEM_02502 1.62e-150 ypgQ - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
MLHAJGEM_02503 2.18e-277 - - - EGP - - - Major Facilitator
MLHAJGEM_02504 1.07e-21 - - - S - - - FRG
MLHAJGEM_02505 3.67e-60 repA - - S - - - Replication initiator protein A
MLHAJGEM_02507 6.25e-115 repE - - K - - - Primase C terminal 1 (PriCT-1)
MLHAJGEM_02508 2.82e-120 - - - D - - - Cellulose biosynthesis protein BcsQ
MLHAJGEM_02509 3.37e-35 - - - - - - - -
MLHAJGEM_02510 4.31e-76 - - - S - - - Bacterial toxin of type II toxin-antitoxin system, YafQ
MLHAJGEM_02511 1.11e-59 - - - D ko:K19159 - ko00000,ko02048 Antitoxin component of a toxin-antitoxin (TA) module
MLHAJGEM_02512 1.53e-138 - - - L - - - Integrase
MLHAJGEM_02513 2.27e-81 - - - - - - - -
MLHAJGEM_02514 1.04e-194 - - - L - - - Initiator Replication protein
MLHAJGEM_02515 4.81e-83 - - - S - - - Protein of unknown function, DUF536
MLHAJGEM_02516 3.53e-69 - - - S - - - Protein of unknown function (DUF2992)
MLHAJGEM_02517 1.06e-64 - - - - - - - -
MLHAJGEM_02518 1.83e-82 - - - S - - - Tetratricopeptide repeat
MLHAJGEM_02519 2.68e-80 - - - S - - - MTH538 TIR-like domain (DUF1863)
MLHAJGEM_02520 7.51e-125 pinR1 - - L - - - Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
MLHAJGEM_02521 6.06e-312 - 1.11.2.4 - C ko:K15629 - ko00000,ko00199,ko01000 Cytochrome P450
MLHAJGEM_02522 2.64e-114 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 DJ-1/PfpI family
MLHAJGEM_02523 4.51e-84 - - - - - - - -
MLHAJGEM_02524 2e-98 yugI - - J ko:K07570,ko:K07571 - ko00000 general stress protein
MLHAJGEM_02525 5.16e-141 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MLHAJGEM_02526 7.18e-153 dedA - - S ko:K03975 - ko00000 SNARE-like domain protein
MLHAJGEM_02527 4.69e-151 - - - S - - - Protein of unknown function (DUF1461)
MLHAJGEM_02528 8.38e-188 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MLHAJGEM_02529 3.94e-116 yutD - - S - - - Protein of unknown function (DUF1027)
MLHAJGEM_02530 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
MLHAJGEM_02531 5.77e-151 - - - S - - - Calcineurin-like phosphoesterase
MLHAJGEM_02532 0.0 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
MLHAJGEM_02533 4.7e-282 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MLHAJGEM_02534 2.22e-236 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
MLHAJGEM_02536 1.85e-112 - - - S - - - Prokaryotic N-terminal methylation motif
MLHAJGEM_02537 3.03e-27 - - - - ko:K02671 - ko00000,ko02035,ko02044 -
MLHAJGEM_02538 1.5e-108 - - - NU ko:K02246 - ko00000,ko00002,ko02044 general secretion pathway protein
MLHAJGEM_02539 1.97e-72 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 competence protein ComGC
MLHAJGEM_02540 6.2e-242 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
MLHAJGEM_02541 1.04e-223 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
MLHAJGEM_02542 1.19e-204 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MLHAJGEM_02543 2.21e-168 yebC - - K - - - Transcriptional regulatory protein
MLHAJGEM_02544 4.92e-65 - - - S ko:K09004 - ko00000 DsrE/DsrF-like family
MLHAJGEM_02545 3.21e-210 - - - G - - - Xylose isomerase domain protein TIM barrel
MLHAJGEM_02546 5.44e-232 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
MLHAJGEM_02547 1.55e-275 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
MLHAJGEM_02548 9.11e-106 - - - K - - - helix_turn_helix, mercury resistance
MLHAJGEM_02549 1.6e-96 - - - - - - - -
MLHAJGEM_02550 1.88e-75 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MLHAJGEM_02551 2.31e-202 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
MLHAJGEM_02552 2.74e-288 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MLHAJGEM_02553 2.29e-112 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MLHAJGEM_02554 4.6e-113 ykuL - - S - - - (CBS) domain
MLHAJGEM_02555 1.92e-123 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
MLHAJGEM_02556 8.49e-144 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MLHAJGEM_02557 8.74e-195 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
MLHAJGEM_02558 2.57e-118 yslB - - S - - - Protein of unknown function (DUF2507)
MLHAJGEM_02559 3e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
MLHAJGEM_02560 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MLHAJGEM_02561 1.06e-49 - - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MLHAJGEM_02562 1.31e-63 yrzB - - S - - - Belongs to the UPF0473 family
MLHAJGEM_02563 5.39e-96 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MLHAJGEM_02564 5e-57 yrzL - - S - - - Belongs to the UPF0297 family
MLHAJGEM_02565 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MLHAJGEM_02566 2.79e-316 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MLHAJGEM_02567 8.32e-227 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
MLHAJGEM_02568 2.48e-276 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MLHAJGEM_02569 1.79e-61 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
MLHAJGEM_02570 9.91e-289 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MLHAJGEM_02571 5.87e-256 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MLHAJGEM_02572 3.73e-239 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MLHAJGEM_02573 2.83e-138 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MLHAJGEM_02574 2.07e-118 - - - - - - - -
MLHAJGEM_02575 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
MLHAJGEM_02576 1.35e-93 - - - - - - - -
MLHAJGEM_02577 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MLHAJGEM_02578 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MLHAJGEM_02579 6.18e-197 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 YmdB-like protein
MLHAJGEM_02580 6.57e-291 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
MLHAJGEM_02581 2.43e-264 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MLHAJGEM_02582 9.01e-294 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
MLHAJGEM_02583 1.92e-127 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MLHAJGEM_02584 1.64e-171 ymfM - - S ko:K15539 - ko00000 Helix-turn-helix domain
MLHAJGEM_02585 0.0 ymfH - - S - - - Peptidase M16
MLHAJGEM_02586 1.02e-295 ymfF - - S - - - Peptidase M16 inactive domain protein
MLHAJGEM_02587 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
MLHAJGEM_02588 2.61e-199 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
MLHAJGEM_02589 3.17e-149 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MLHAJGEM_02590 1.89e-141 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
MLHAJGEM_02591 1.23e-187 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
MLHAJGEM_02592 3.81e-150 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
MLHAJGEM_02593 9.47e-115 mreD - - M ko:K03571 - ko00000,ko03036 rod shape-determining protein MreD
MLHAJGEM_02594 3.76e-184 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
MLHAJGEM_02595 1.74e-211 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
MLHAJGEM_02596 1.15e-150 radC - - L ko:K03630 - ko00000 DNA repair protein
MLHAJGEM_02597 9.36e-317 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
MLHAJGEM_02598 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MLHAJGEM_02599 3.56e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MLHAJGEM_02600 3.17e-299 gshF 6.3.2.2 - H ko:K01919,ko:K16786,ko:K16787 ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the glutamate--cysteine ligase type 1 family
MLHAJGEM_02601 1.09e-291 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MLHAJGEM_02602 2.22e-278 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
MLHAJGEM_02604 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MLHAJGEM_02605 5.28e-105 yebR 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
MLHAJGEM_02606 1.07e-137 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MLHAJGEM_02607 3.3e-144 yktB - - S - - - Belongs to the UPF0637 family
MLHAJGEM_02608 9.83e-106 XK27_05190 - - S - - - Protein of unknown function (DUF1694)
MLHAJGEM_02609 1.57e-142 - - - S - - - Protein of unknown function (DUF1648)
MLHAJGEM_02610 1.52e-57 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
MLHAJGEM_02611 0.0 gshAB 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
MLHAJGEM_02612 7.27e-303 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
MLHAJGEM_02613 1.34e-52 - - - - - - - -
MLHAJGEM_02614 2.37e-107 uspA - - T - - - universal stress protein
MLHAJGEM_02615 4.68e-260 bla2 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
MLHAJGEM_02616 4.7e-207 - - - K - - - Helix-turn-helix XRE-family like proteins
MLHAJGEM_02617 0.0 glpQ3 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Glycerophosphoryl diester phosphodiesterase family
MLHAJGEM_02618 3.78e-272 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
MLHAJGEM_02619 6.2e-241 - 1.1.1.1, 1.6.5.5 - C ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
MLHAJGEM_02620 3.26e-227 - - - S - - - Protein of unknown function (DUF2785)
MLHAJGEM_02621 3.34e-215 hicD3 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
MLHAJGEM_02622 3.03e-191 metQ - - M ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
MLHAJGEM_02623 2.1e-151 metI - - U ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MLHAJGEM_02624 2.24e-239 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MLHAJGEM_02625 5.33e-63 gcsH2 - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 glycine cleavage
MLHAJGEM_02626 2.15e-280 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
MLHAJGEM_02627 2.54e-46 - - - S - - - Protein of unknown function (DUF2969)
MLHAJGEM_02628 1.52e-57 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
MLHAJGEM_02629 1.44e-230 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
MLHAJGEM_02630 1.96e-131 - - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
MLHAJGEM_02631 2.94e-315 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MLHAJGEM_02632 5.95e-74 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
MLHAJGEM_02633 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MLHAJGEM_02634 9.14e-213 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MLHAJGEM_02635 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MLHAJGEM_02636 2.03e-118 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MLHAJGEM_02637 5.41e-77 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MLHAJGEM_02638 1.81e-37 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MLHAJGEM_02639 4.82e-165 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
MLHAJGEM_02640 1.44e-293 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
MLHAJGEM_02641 7.81e-148 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MLHAJGEM_02642 8.7e-297 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MLHAJGEM_02643 4.39e-244 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MLHAJGEM_02644 9.47e-202 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MLHAJGEM_02645 1.88e-251 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MLHAJGEM_02646 5e-141 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
MLHAJGEM_02647 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Domain of unknown function (DUF1727)
MLHAJGEM_02648 1.06e-174 cobQ - - S ko:K07009 - ko00000 glutamine amidotransferase
MLHAJGEM_02649 4.07e-249 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
MLHAJGEM_02650 1.53e-244 ampC - - V - - - Beta-lactamase
MLHAJGEM_02651 8.57e-41 - - - - - - - -
MLHAJGEM_02652 1.9e-260 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
MLHAJGEM_02653 1.33e-77 - - - - - - - -
MLHAJGEM_02654 1.54e-181 - - - - - - - -
MLHAJGEM_02655 0.0 yfiC - - V ko:K06147 - ko00000,ko02000 ABC transporter
MLHAJGEM_02656 0.0 ycfI - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
MLHAJGEM_02657 1.33e-87 yxeA - - S - - - Protein of unknown function (DUF1093)
MLHAJGEM_02658 5.96e-182 icaB - - G - - - Polysaccharide deacetylase
MLHAJGEM_02660 7.13e-16 - - - S - - - Haemolysin XhlA
MLHAJGEM_02661 2.01e-107 - - - M ko:K07273 - ko00000 hydrolase, family 25
MLHAJGEM_02664 5.63e-75 - - - S - - - Phage minor structural protein
MLHAJGEM_02666 2.5e-191 - - - L - - - Phage tail tape measure protein TP901
MLHAJGEM_02668 1.6e-156 - - - - - - - -
MLHAJGEM_02670 2.57e-22 - - - - - - - -
MLHAJGEM_02675 8.48e-16 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
MLHAJGEM_02676 7.72e-43 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MLHAJGEM_02677 2.79e-07 - - - - - - - -
MLHAJGEM_02678 1.07e-98 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 N-acetylmuramoyl-L-alanine amidase
MLHAJGEM_02679 1.62e-157 - - - P ko:K02077 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
MLHAJGEM_02680 6.39e-09 - - - - - - - -
MLHAJGEM_02681 4.05e-39 XK27_10395 - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
MLHAJGEM_02682 5.3e-49 - - - L - - - DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MLHAJGEM_02683 2.21e-84 - - - D - - - AAA domain
MLHAJGEM_02684 8.83e-06 - - - - - - - -
MLHAJGEM_02687 4.97e-127 soj - - D - - - CobQ CobB MinD ParA nucleotide binding domain protein
MLHAJGEM_02689 7.55e-53 - - - S - - - Antitoxin component of a toxin-antitoxin (TA) module
MLHAJGEM_02690 3.16e-59 - - - T ko:K07172 - ko00000,ko02048 Antidote-toxin recognition MazE, bacterial antitoxin
MLHAJGEM_02691 1.53e-138 - - - L - - - Integrase
MLHAJGEM_02692 3.78e-28 - - - - - - - -
MLHAJGEM_02693 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
MLHAJGEM_02694 3.67e-154 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MLHAJGEM_02695 1.35e-55 - - - S - - - COG NOG38524 non supervised orthologous group
MLHAJGEM_02696 0.000411 gsiB - - S ko:K06884 - ko00000 general stress protein
MLHAJGEM_02697 8.92e-222 - - - L - - - Replication protein
MLHAJGEM_02698 2.48e-56 - - - S - - - Plasmid replication protein
MLHAJGEM_02700 1.35e-135 mob - - D - - - Plasmid recombination enzyme
MLHAJGEM_02701 7.68e-84 - - - - - - - -
MLHAJGEM_02702 1.76e-132 - - - L - - - Phage integrase family
MLHAJGEM_02703 1.55e-55 - - - - - - - -
MLHAJGEM_02704 2.41e-56 - - - - - - - -
MLHAJGEM_02705 1.15e-152 - - - - - - - -
MLHAJGEM_02706 4.02e-301 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
MLHAJGEM_02707 5.2e-156 - - - K - - - Bacterial regulatory proteins, tetR family
MLHAJGEM_02708 8.9e-96 ywnA - - K - - - Transcriptional regulator
MLHAJGEM_02709 9.53e-93 - - - - - - - -
MLHAJGEM_02710 3.37e-129 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
MLHAJGEM_02711 5.24e-185 - - - - - - - -
MLHAJGEM_02712 0.0 pts5ABC - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
MLHAJGEM_02713 0.0 pts4ABC - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MLHAJGEM_02714 7.48e-125 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
MLHAJGEM_02715 2.49e-277 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
MLHAJGEM_02716 1.68e-166 treR - - K ko:K03486 - ko00000,ko03000 UTRA
MLHAJGEM_02717 1.1e-56 - - - - - - - -
MLHAJGEM_02718 7.55e-58 - - - S - - - Protein of unknown function (DUF2089)
MLHAJGEM_02719 1.41e-177 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
MLHAJGEM_02720 6.72e-203 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
MLHAJGEM_02721 7.23e-209 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
MLHAJGEM_02722 5.78e-268 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
MLHAJGEM_02723 3.02e-124 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Bacterial transferase hexapeptide (six repeats)
MLHAJGEM_02724 1.17e-244 - 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 pfkB family carbohydrate kinase
MLHAJGEM_02725 1.01e-165 - 4.1.2.14 - S ko:K17463 ko00030,ko01100,ko01120,map00030,map01100,map01120 ko00000,ko00001,ko00002,ko01000 KDGP aldolase
MLHAJGEM_02726 5.06e-259 selA 2.9.1.1 - H ko:K01042 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko01000 L-seryl-tRNA selenium transferase
MLHAJGEM_02727 2.45e-269 dho 3.5.2.3 - S ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Amidohydrolase family
MLHAJGEM_02728 9.23e-270 - - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
MLHAJGEM_02729 6.14e-53 - - - - - - - -
MLHAJGEM_02730 3.35e-290 pts3C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MLHAJGEM_02731 1.89e-159 - - - K - - - helix_turn_helix gluconate operon transcriptional repressor
MLHAJGEM_02732 5.21e-126 - - - S ko:K19784 - ko00000 NADPH-dependent FMN reductase
MLHAJGEM_02733 0.0 - - - S ko:K13730 ko05100,map05100 ko00000,ko00001 Uncharacterized protein conserved in bacteria (DUF2252)
MLHAJGEM_02734 1.2e-106 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Belongs to the NDK family
MLHAJGEM_02735 2.98e-90 - - - - - - - -
MLHAJGEM_02736 1.43e-124 - - - - - - - -
MLHAJGEM_02737 5.92e-67 - - - - - - - -
MLHAJGEM_02738 7.99e-75 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
MLHAJGEM_02739 3.7e-106 - - - - - - - -
MLHAJGEM_02740 3.71e-282 mtlD 1.1.1.17 - C ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 mannitol-1-phosphate 5-dehydrogenase activity
MLHAJGEM_02741 5.33e-103 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MLHAJGEM_02742 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 Mga helix-turn-helix domain
MLHAJGEM_02743 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
MLHAJGEM_02744 2.75e-121 pepD1 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
MLHAJGEM_02745 4.5e-201 pepD1 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
MLHAJGEM_02746 3.16e-170 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MLHAJGEM_02747 6.95e-91 - - - - - - - -
MLHAJGEM_02748 3.68e-102 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MLHAJGEM_02749 2.16e-201 dkgB - - S - - - reductase
MLHAJGEM_02750 2.28e-114 gpo 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
MLHAJGEM_02751 1.66e-130 - - - S ko:K16925 - ko00000,ko00002,ko02000 ABC transporter permease
MLHAJGEM_02752 0.0 - - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
MLHAJGEM_02753 4.3e-150 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
MLHAJGEM_02754 0.0 - - - S ko:K18231,ko:K19349 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ATPases associated with a variety of cellular activities
MLHAJGEM_02755 5.66e-74 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MLHAJGEM_02756 3.18e-77 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MLHAJGEM_02757 3.81e-18 - - - - - - - -
MLHAJGEM_02758 1.29e-278 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MLHAJGEM_02759 4.56e-210 fbpA - - K - - - Domain of unknown function (DUF814)
MLHAJGEM_02760 1.15e-79 - - - S - - - Domain of unknown function (DU1801)
MLHAJGEM_02761 6.33e-46 - - - - - - - -
MLHAJGEM_02762 7.12e-229 yghZ - - C ko:K19265 - ko00000,ko01000 Aldo keto reductase family protein
MLHAJGEM_02763 6.7e-148 pgm1 - - G - - - phosphoglycerate mutase
MLHAJGEM_02764 1.24e-259 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MLHAJGEM_02765 5.89e-278 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MLHAJGEM_02766 9.25e-103 yiaC - - K ko:K03826 - ko00000,ko01000 Acetyltransferase (GNAT) domain
MLHAJGEM_02767 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MLHAJGEM_02768 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MLHAJGEM_02769 1.03e-201 - - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
MLHAJGEM_02771 0.0 - - - M - - - domain protein
MLHAJGEM_02772 1.89e-169 mleR - - K - - - LysR substrate binding domain
MLHAJGEM_02773 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
MLHAJGEM_02774 0.0 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
MLHAJGEM_02775 7.81e-209 - 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 nadph quinone reductase
MLHAJGEM_02776 0.0 - 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
MLHAJGEM_02777 2.4e-230 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional regulator, LacI family
MLHAJGEM_02778 0.0 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
MLHAJGEM_02779 0.0 scrA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MLHAJGEM_02780 3.63e-215 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
MLHAJGEM_02781 8.23e-61 ygbF - - S - - - Sugar efflux transporter for intercellular exchange
MLHAJGEM_02782 0.0 - 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Glycosyl hydrolase family 85
MLHAJGEM_02783 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
MLHAJGEM_02784 2.44e-267 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MLHAJGEM_02785 0.0 malS 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 Glycogen debranching enzyme, glucanotransferase domain
MLHAJGEM_02786 1.01e-190 malA - - S - - - maltodextrose utilization protein MalA
MLHAJGEM_02787 2.83e-206 malD - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MLHAJGEM_02788 3.74e-302 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MLHAJGEM_02789 9.45e-299 mdxE - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
MLHAJGEM_02790 0.0 malA1 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain
MLHAJGEM_02791 1.83e-231 yvdE - - K - - - helix_turn _helix lactose operon repressor
MLHAJGEM_02792 6.08e-141 malR1 - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
MLHAJGEM_02793 2.5e-84 malR1 - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
MLHAJGEM_02794 4e-172 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
MLHAJGEM_02795 6.76e-75 dhaM 2.7.1.121 - S ko:K05881 ko00561,map00561 ko00000,ko00001,ko01000,ko02000 PTS system fructose IIA component
MLHAJGEM_02796 2.75e-131 dhaL 2.7.1.121 - S ko:K05879 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak2
MLHAJGEM_02797 3.19e-238 dhaK 2.7.1.121 - G ko:K05878 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak1 domain
MLHAJGEM_02798 6.73e-243 dhaK2 2.7.1.28, 2.7.1.29, 4.6.1.15 - G ko:K00863 ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622 ko00000,ko00001,ko00002,ko01000 Dak1 domain
MLHAJGEM_02799 3.73e-121 XK27_02085 - - K - - - Bacterial regulatory proteins, tetR family
MLHAJGEM_02801 8.89e-96 - - - T - - - ECF transporter, substrate-specific component
MLHAJGEM_02802 0.0 etfA 1.3.1.108 - C ko:K03522,ko:K22432 - ko00000,ko01000,ko04147 Electron transfer flavoprotein FAD-binding domain
MLHAJGEM_02803 9.37e-150 - - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
MLHAJGEM_02804 0.0 - - - M ko:K01992 - ko00000,ko00002,ko02000 Exporter of polyketide antibiotics
MLHAJGEM_02805 2.46e-217 ybhF_1 - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
MLHAJGEM_02806 1.01e-184 dhrS4 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Oxidoreductase, short chain dehydrogenase reductase family protein
MLHAJGEM_02807 3.37e-115 - - - - - - - -
MLHAJGEM_02808 3.16e-191 - - - - - - - -
MLHAJGEM_02809 2.58e-181 - - - - - - - -
MLHAJGEM_02810 4.14e-72 - - - K - - - Transcriptional regulator PadR-like family
MLHAJGEM_02811 4.37e-167 - - - K ko:K03492 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
MLHAJGEM_02812 2.57e-128 - - - S ko:K16924 - ko00000,ko00002,ko02000 UPF0397 protein
MLHAJGEM_02813 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MLHAJGEM_02814 3.28e-193 cbiQ - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
MLHAJGEM_02815 2.64e-267 - - - C - - - Oxidoreductase
MLHAJGEM_02816 0.0 - - - - - - - -
MLHAJGEM_02817 2.65e-116 - - - - - - - -
MLHAJGEM_02818 0.0 l1n 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
MLHAJGEM_02819 7.84e-106 - - - F - - - Nucleoside 2-deoxyribosyltransferase like
MLHAJGEM_02820 1.66e-212 - 1.1.1.65 - C ko:K05275 ko00750,ko01100,ko01120,map00750,map01100,map01120 ko00000,ko00001,ko01000 Aldo keto reductase
MLHAJGEM_02821 2.16e-204 morA - - S - - - reductase
MLHAJGEM_02823 1.61e-273 yycB - - P ko:K03449 - ko00000,ko02000 Transporter, major facilitator family protein
MLHAJGEM_02824 3.98e-68 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
MLHAJGEM_02825 5.38e-290 - - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
MLHAJGEM_02826 3.99e-96 hsp1 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
MLHAJGEM_02827 4.45e-99 - - - K - - - Transcriptional regulator
MLHAJGEM_02828 1.72e-142 azo1 1.5.1.36, 1.7.1.6 - S ko:K03206,ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
MLHAJGEM_02829 2.92e-38 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
MLHAJGEM_02830 0.0 pacL1 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
MLHAJGEM_02831 5.08e-192 - - - I - - - Alpha/beta hydrolase family
MLHAJGEM_02832 5.18e-159 - - - - - - - -
MLHAJGEM_02833 0.0 yifK - - E ko:K03293 - ko00000 Amino acid permease
MLHAJGEM_02834 3.55e-109 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
MLHAJGEM_02835 0.0 - - - L - - - HIRAN domain
MLHAJGEM_02836 1.76e-176 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
MLHAJGEM_02837 4.15e-261 thiP - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
MLHAJGEM_02838 5.4e-143 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
MLHAJGEM_02839 4.13e-189 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
MLHAJGEM_02840 1.87e-175 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MLHAJGEM_02841 6.11e-145 - - - C - - - Zinc-binding dehydrogenase
MLHAJGEM_02842 6.38e-194 larE - - S ko:K06864 - ko00000 NAD synthase
MLHAJGEM_02843 1.19e-170 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
MLHAJGEM_02844 6.32e-99 larC2 4.99.1.12 - S ko:K09121 - ko00000,ko01000 Protein of unknown function DUF111
MLHAJGEM_02845 2.03e-179 larC 4.99.1.12 - S ko:K09121 - ko00000,ko01000 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
MLHAJGEM_02846 2.65e-162 larB - - S ko:K06898 - ko00000 AIR carboxylase
MLHAJGEM_02847 7.9e-306 larA 5.1.2.1 - S ko:K22373 ko00620,map00620 ko00000,ko00001,ko01000 Domain of unknown function (DUF2088)
MLHAJGEM_02848 0.0 mleS 1.1.1.38, 4.1.1.101 - C ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme
MLHAJGEM_02849 2.43e-216 mleP - - S ko:K07088 - ko00000 Sodium Bile acid symporter family
MLHAJGEM_02850 1.45e-63 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
MLHAJGEM_02851 1.62e-105 - - - L - - - Transposase DDE domain
MLHAJGEM_02852 2.3e-140 is18 - - L - - - Integrase core domain
MLHAJGEM_02854 1.98e-106 ybfG - - M - - - peptidoglycan-binding domain-containing protein
MLHAJGEM_02855 3.76e-32 - - - L ko:K07483,ko:K07497 - ko00000 Helix-turn-helix domain
MLHAJGEM_02856 2.45e-118 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
MLHAJGEM_02857 3.91e-102 - - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
MLHAJGEM_02858 2.01e-87 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
MLHAJGEM_02859 7.39e-61 - - - M - - - domain protein
MLHAJGEM_02860 5.06e-15 - 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S14 family
MLHAJGEM_02861 8.33e-102 - - - L - - - PFAM Integrase catalytic region
MLHAJGEM_02862 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MLHAJGEM_02863 4.64e-294 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
MLHAJGEM_02864 9.26e-175 cdsA 2.7.7.41 - I ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
MLHAJGEM_02865 3.71e-189 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MLHAJGEM_02866 9.83e-113 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MLHAJGEM_02867 3.01e-165 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
MLHAJGEM_02868 1.88e-194 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MLHAJGEM_02869 2.12e-183 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
MLHAJGEM_02870 2.92e-172 - - - S ko:K07025 - ko00000 Haloacid dehalogenase-like hydrolase
MLHAJGEM_02871 1.92e-239 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MLHAJGEM_02872 9.79e-65 yazA - - L ko:K07461 - ko00000 GIY-YIG catalytic domain protein
MLHAJGEM_02873 3.65e-172 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
MLHAJGEM_02874 9.88e-152 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
MLHAJGEM_02875 3.96e-44 XK26_06720 - - S ko:K09976 - ko00000 Uncharacterised protein family (UPF0154)
MLHAJGEM_02876 7.68e-48 ynzC - - S - - - UPF0291 protein
MLHAJGEM_02877 7.22e-149 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MLHAJGEM_02878 6.4e-122 - - - - - - - -
MLHAJGEM_02879 6.62e-278 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
MLHAJGEM_02880 1.01e-100 - - - - - - - -
MLHAJGEM_02881 3.81e-87 - - - - - - - -
MLHAJGEM_02882 2.3e-226 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 Glycosyltransferase like family 2
MLHAJGEM_02883 6.27e-131 - - - L - - - Helix-turn-helix domain
MLHAJGEM_02884 6.34e-281 ywtF_2 - - K - - - Cell envelope-related transcriptional attenuator domain
MLHAJGEM_02885 1.1e-183 - - - P ko:K02049 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
MLHAJGEM_02886 0.0 - - - P ko:K02050 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MLHAJGEM_02887 2.38e-294 rodA - - D ko:K05837 - ko00000,ko03036 Cell cycle protein
MLHAJGEM_02893 3.19e-50 - - - S - - - Haemolysin XhlA
MLHAJGEM_02894 4.11e-227 - - - M - - - Glycosyl hydrolases family 25
MLHAJGEM_02895 5.98e-58 virB5 - - U ko:K03200,ko:K20266 ko02024,ko03070,map02024,map03070 ko00000,ko00001,ko00002,ko02044 conjugation
MLHAJGEM_02896 9.65e-71 - - - - - - - -
MLHAJGEM_02899 6.93e-125 - - - - - - - -
MLHAJGEM_02900 0.0 - - - S - - - Phage minor structural protein
MLHAJGEM_02901 2.85e-284 - - - S - - - Phage tail protein
MLHAJGEM_02902 0.0 - - - L - - - Phage tail tape measure protein TP901
MLHAJGEM_02903 4.32e-32 - - - - - - - -
MLHAJGEM_02904 6.45e-74 - - - S - - - Phage tail assembly chaperone proteins, TAC
MLHAJGEM_02905 1.31e-134 - - - S - - - Phage tail tube protein
MLHAJGEM_02906 5.93e-80 - - - S - - - Protein of unknown function (DUF806)
MLHAJGEM_02907 1.93e-87 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
MLHAJGEM_02908 1.2e-76 - - - S - - - Phage head-tail joining protein
MLHAJGEM_02909 2.79e-66 - - - S - - - Phage gp6-like head-tail connector protein
MLHAJGEM_02910 1.08e-289 - - - S - - - Phage capsid family
MLHAJGEM_02911 2.18e-166 - 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S14 family
MLHAJGEM_02912 1.21e-284 - - - S - - - Phage portal protein
MLHAJGEM_02913 1.35e-34 - - - S - - - Protein of unknown function (DUF1056)
MLHAJGEM_02914 0.0 - - - S - - - Phage Terminase
MLHAJGEM_02915 4.02e-104 - - - S - - - Phage terminase, small subunit
MLHAJGEM_02916 4.83e-23 - - - S - - - HNH endonuclease
MLHAJGEM_02917 2.09e-94 - - - L - - - HNH nucleases
MLHAJGEM_02918 4.05e-11 - - - V - - - HNH nucleases
MLHAJGEM_02920 1.63e-98 - - - S - - - Transcriptional regulator, RinA family
MLHAJGEM_02923 7.14e-21 - - - - - - - -
MLHAJGEM_02924 1.75e-63 - - - - - - - -
MLHAJGEM_02926 2.44e-170 - - - L ko:K02315 - ko00000,ko03032 IstB-like ATP binding protein
MLHAJGEM_02927 1.47e-44 - - - L - - - Conserved phage C-terminus (Phg_2220_C)
MLHAJGEM_02928 1.24e-168 - - - S - - - Putative HNHc nuclease
MLHAJGEM_02929 1.12e-136 - - - S - - - Protein of unknown function (DUF669)
MLHAJGEM_02930 8.37e-153 - - - S - - - AAA domain
MLHAJGEM_02931 9.55e-185 - - - S - - - Protein of unknown function (DUF1351)
MLHAJGEM_02933 2.26e-22 - - - - - - - -
MLHAJGEM_02939 3.96e-78 - - - S - - - ORF6C domain
MLHAJGEM_02940 1.32e-52 - - - K - - - Cro/C1-type HTH DNA-binding domain
MLHAJGEM_02941 3.48e-97 - - - S - - - sequence-specific DNA binding
MLHAJGEM_02942 7.83e-68 - - - - - - - -
MLHAJGEM_02943 3.09e-75 int3 - - L - - - Belongs to the 'phage' integrase family
MLHAJGEM_02944 1.02e-42 - - - - - - - -
MLHAJGEM_02945 5.05e-184 - - - Q - - - Methyltransferase
MLHAJGEM_02946 2.84e-75 ybjQ - - S - - - Belongs to the UPF0145 family
MLHAJGEM_02947 4.58e-212 - - - EGP - - - Major facilitator Superfamily
MLHAJGEM_02948 1.04e-38 - - - EGP - - - Major facilitator Superfamily
MLHAJGEM_02949 4.57e-135 - - - K - - - Helix-turn-helix domain
MLHAJGEM_02950 1.52e-120 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MLHAJGEM_02951 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
MLHAJGEM_02952 1.84e-67 - - - S - - - Lipopolysaccharide assembly protein A domain
MLHAJGEM_02953 8.27e-179 - - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
MLHAJGEM_02954 2.05e-228 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MLHAJGEM_02955 6.62e-62 - - - - - - - -
MLHAJGEM_02956 8.98e-311 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MLHAJGEM_02957 3.02e-175 fruR - - K ko:K03436 - ko00000,ko03000 DeoR C terminal sensor domain
MLHAJGEM_02958 7.34e-219 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
MLHAJGEM_02959 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase System
MLHAJGEM_02960 0.0 - 3.1.4.53 - S ko:K03651 ko00230,ko02025,map00230,map02025 ko00000,ko00001,ko01000 Calcineurin-like phosphoesterase
MLHAJGEM_02961 0.0 cps4J - - S - - - MatE
MLHAJGEM_02962 7.66e-225 cps4I - - M - - - Glycosyltransferase like family 2
MLHAJGEM_02963 2.59e-295 - - - - - - - -
MLHAJGEM_02964 1.95e-228 cps4G - - M - - - Glycosyltransferase Family 4
MLHAJGEM_02965 2.65e-248 cps4F - - M - - - Glycosyl transferases group 1
MLHAJGEM_02966 1.11e-162 tuaA - - M - - - Bacterial sugar transferase
MLHAJGEM_02967 7.15e-230 cps4D 5.1.3.2, 5.1.3.25 - M ko:K01784,ko:K17947 ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130 ko00000,ko00001,ko00002,ko01000 RmlD substrate binding domain
MLHAJGEM_02968 5.54e-189 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
MLHAJGEM_02969 1.28e-109 ywqD - - D - - - Capsular exopolysaccharide family
MLHAJGEM_02970 4.28e-27 ywqD - - D - - - Capsular exopolysaccharide family
MLHAJGEM_02971 8.82e-164 epsB - - M - - - biosynthesis protein
MLHAJGEM_02972 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MLHAJGEM_02973 3.97e-173 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MLHAJGEM_02974 0.0 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
MLHAJGEM_02975 5.12e-31 - - - - - - - -
MLHAJGEM_02976 6.47e-95 - - - S - - - Iron-sulphur cluster biosynthesis
MLHAJGEM_02977 1.3e-65 - - - S - - - mazG nucleotide pyrophosphohydrolase
MLHAJGEM_02978 9.6e-143 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
MLHAJGEM_02979 7.8e-300 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MLHAJGEM_02980 3.21e-288 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MLHAJGEM_02981 1.78e-285 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MLHAJGEM_02982 9.34e-201 - - - S - - - Tetratricopeptide repeat
MLHAJGEM_02983 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MLHAJGEM_02984 1.29e-200 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MLHAJGEM_02985 1.71e-83 - - - EGP - - - Major Facilitator Superfamily
MLHAJGEM_02986 5.82e-113 - - - EGP - - - Major Facilitator Superfamily
MLHAJGEM_02987 2.9e-56 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MLHAJGEM_02988 1.18e-46 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
MLHAJGEM_02989 6.93e-239 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
MLHAJGEM_02990 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
MLHAJGEM_02991 7.1e-116 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
MLHAJGEM_02992 2.1e-161 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
MLHAJGEM_02993 3.01e-251 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
MLHAJGEM_02994 2.99e-109 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MLHAJGEM_02995 7.08e-131 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
MLHAJGEM_02996 1.91e-66 ylbG - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
MLHAJGEM_02997 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MLHAJGEM_02998 5.06e-261 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
MLHAJGEM_02999 0.0 - - - - - - - -
MLHAJGEM_03000 0.0 icaA - - M - - - Glycosyl transferase family group 2
MLHAJGEM_03001 9.51e-135 - - - - - - - -
MLHAJGEM_03002 0.000623 - - - L - - - COG3547 Transposase and inactivated derivatives
MLHAJGEM_03003 2.22e-78 - - - L - - - Psort location Cytoplasmic, score
MLHAJGEM_03004 2.34e-46 traE - - U - - - Psort location Cytoplasmic, score
MLHAJGEM_03005 3.17e-45 traE - - U - - - Psort location Cytoplasmic, score
MLHAJGEM_03006 2.15e-104 - - - - - - - -
MLHAJGEM_03007 1.73e-186 B4168_4126 - - L ko:K07493 - ko00000 Transposase
MLHAJGEM_03008 7.32e-174 - - - L ko:K07482 - ko00000 Integrase core domain
MLHAJGEM_03009 0.0 - - - L - - - DNA helicase
MLHAJGEM_03010 5.87e-181 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Carbon-nitrogen hydrolase
MLHAJGEM_03011 7.86e-242 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
MLHAJGEM_03012 3.67e-164 - - - K - - - UbiC transcription regulator-associated domain protein
MLHAJGEM_03013 0.0 chbC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MLHAJGEM_03014 9.68e-34 - - - - - - - -
MLHAJGEM_03015 3.55e-99 - - - S - - - Domain of unknown function (DUF3284)
MLHAJGEM_03016 0.0 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MLHAJGEM_03017 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MLHAJGEM_03018 6.97e-209 - - - GK - - - ROK family
MLHAJGEM_03019 9.75e-175 yecA - - K - - - Helix-turn-helix domain, rpiR family
MLHAJGEM_03020 2.94e-244 dus - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MLHAJGEM_03021 1.72e-259 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
MLHAJGEM_03022 1.36e-214 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
MLHAJGEM_03023 1.37e-290 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
MLHAJGEM_03024 5.2e-226 - - - - - - - -
MLHAJGEM_03025 2.14e-171 cobB - - K ko:K12410 - ko00000,ko01000 SIR2 family
MLHAJGEM_03026 1.12e-205 yunF - - F - - - Protein of unknown function DUF72
MLHAJGEM_03027 1.33e-91 - - - F - - - DNA mismatch repair protein MutT
MLHAJGEM_03028 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MLHAJGEM_03030 3.36e-268 - - - EGP ko:K02030 - ko00000,ko00002,ko02000 Drug resistance transporter Bcr CflA subfamily
MLHAJGEM_03031 8.41e-127 mutR - - K ko:K20373,ko:K20375 ko02024,map02024 ko00000,ko00001,ko03000 sequence-specific DNA binding
MLHAJGEM_03033 1.63e-187 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
MLHAJGEM_03034 1.08e-125 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MLHAJGEM_03035 7.17e-203 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MLHAJGEM_03036 6.87e-50 veg - - S - - - Biofilm formation stimulator VEG
MLHAJGEM_03037 1.07e-207 ispE 2.7.1.148 - F ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MLHAJGEM_03038 1.9e-230 - - - S ko:K06889 - ko00000 Prolyl oligopeptidase family
MLHAJGEM_03039 8.05e-166 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
MLHAJGEM_03040 6.39e-169 znuB - - U ko:K02075,ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
MLHAJGEM_03041 1.96e-189 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
MLHAJGEM_03042 3.28e-298 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MLHAJGEM_03043 9.45e-195 bla1 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
MLHAJGEM_03044 6.31e-226 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MLHAJGEM_03045 2.82e-236 - - - S - - - DUF218 domain
MLHAJGEM_03046 4.31e-179 - - - - - - - -
MLHAJGEM_03047 5.9e-191 yxeH - - S - - - hydrolase
MLHAJGEM_03048 0.0 ywfO - - S ko:K06885 - ko00000 HD domain protein
MLHAJGEM_03049 6.05e-198 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 biotin lipoate A B protein ligase
MLHAJGEM_03050 2.87e-101 ywiB - - S - - - Domain of unknown function (DUF1934)
MLHAJGEM_03051 2.96e-89 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MLHAJGEM_03052 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MLHAJGEM_03053 5.84e-312 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MLHAJGEM_03054 9.28e-290 sdaC - - E ko:K03837 - ko00000,ko02000 amino acid
MLHAJGEM_03055 3.06e-158 sdhB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
MLHAJGEM_03056 2.81e-202 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
MLHAJGEM_03057 6.59e-170 - - - S - - - YheO-like PAS domain
MLHAJGEM_03058 4.01e-36 - - - - - - - -
MLHAJGEM_03059 2.08e-302 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MLHAJGEM_03060 6.26e-306 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MLHAJGEM_03061 1.91e-55 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
MLHAJGEM_03062 2.57e-274 - - - J - - - translation release factor activity
MLHAJGEM_03063 3.14e-164 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
MLHAJGEM_03064 5.35e-121 lemA - - S ko:K03744 - ko00000 LemA family
MLHAJGEM_03065 5.58e-195 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
MLHAJGEM_03066 1.84e-189 - - - - - - - -
MLHAJGEM_03067 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MLHAJGEM_03068 0.0 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MLHAJGEM_03069 9.32e-81 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MLHAJGEM_03070 5e-275 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MLHAJGEM_03071 2.58e-85 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
MLHAJGEM_03072 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
MLHAJGEM_03073 5.58e-248 - - - P ko:K02051 - ko00000,ko00002,ko02000 ABC transporter, substratebinding protein
MLHAJGEM_03074 3.03e-202 - - - U ko:K02050 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MLHAJGEM_03075 2.02e-171 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
MLHAJGEM_03076 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
MLHAJGEM_03077 2.61e-260 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
MLHAJGEM_03078 2.97e-243 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MLHAJGEM_03079 1.13e-292 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MLHAJGEM_03080 2.36e-166 argB 2.7.2.8 - F ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
MLHAJGEM_03081 1.9e-277 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine
MLHAJGEM_03082 2.63e-241 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MLHAJGEM_03083 1.3e-110 queT - - S - - - QueT transporter
MLHAJGEM_03084 4.3e-210 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
MLHAJGEM_03085 9.9e-158 pepL 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
MLHAJGEM_03086 4.87e-148 - - - S - - - (CBS) domain
MLHAJGEM_03087 0.0 - - - S - - - Putative peptidoglycan binding domain
MLHAJGEM_03088 4.62e-225 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
MLHAJGEM_03089 2.89e-129 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MLHAJGEM_03090 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MLHAJGEM_03091 0.0 yabM - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
MLHAJGEM_03092 7.72e-57 yabO - - J - - - S4 domain protein
MLHAJGEM_03094 2.02e-83 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
MLHAJGEM_03095 1.07e-103 yabR - - J ko:K07571 - ko00000 RNA binding
MLHAJGEM_03096 0.0 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MLHAJGEM_03097 4.3e-124 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
MLHAJGEM_03098 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MLHAJGEM_03099 1.93e-209 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MLHAJGEM_03100 3.75e-243 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MLHAJGEM_03101 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
MLHAJGEM_03102 2.09e-42 - - - - - - - -
MLHAJGEM_03103 1.19e-29 - - - - - - - -
MLHAJGEM_03104 2.03e-124 tnpR1 - - L - - - Resolvase, N terminal domain
MLHAJGEM_03105 2.14e-44 - - - M - - - CHAP domain
MLHAJGEM_03106 3.59e-26 - - - - - - - -
MLHAJGEM_03107 3.96e-44 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MLHAJGEM_03108 5.84e-279 - - - I - - - transferase activity, transferring acyl groups other than amino-acyl groups
MLHAJGEM_03109 2.91e-230 - - - C - - - Zinc-binding dehydrogenase
MLHAJGEM_03110 0.0 - - - P - - - Cation transporter/ATPase, N-terminus
MLHAJGEM_03111 8.96e-310 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MLHAJGEM_03112 2.66e-306 - - - U ko:K18926 - ko00000,ko00002,ko02000 Major Facilitator Superfamily
MLHAJGEM_03113 4.38e-102 - - - K - - - Transcriptional regulator
MLHAJGEM_03114 3.2e-265 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
MLHAJGEM_03115 0.0 nox - - P - - - Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
MLHAJGEM_03116 4.14e-177 - - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
MLHAJGEM_03117 1.25e-140 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
MLHAJGEM_03118 2.65e-93 spx2 - - P ko:K16509 - ko00000 ArsC family
MLHAJGEM_03119 1.56e-90 - - - S - - - Protein of unknown function (DUF1722)
MLHAJGEM_03120 3.3e-145 - - - GM - - - epimerase
MLHAJGEM_03121 0.0 - - - S - - - Zinc finger, swim domain protein
MLHAJGEM_03122 9.07e-158 - 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 haloacid dehalogenase-like hydrolase
MLHAJGEM_03123 2.31e-132 thgA3 2.3.1.18, 2.3.1.79 - S ko:K00633,ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
MLHAJGEM_03124 2.49e-167 - - - K - - - Helix-turn-helix domain, rpiR family
MLHAJGEM_03125 6.2e-205 - - - S - - - Alpha beta hydrolase
MLHAJGEM_03126 1.76e-146 - - - GM - - - NmrA-like family
MLHAJGEM_03127 2.12e-102 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2255)
MLHAJGEM_03128 2.33e-206 - - - K - - - Transcriptional regulator
MLHAJGEM_03129 9.29e-222 cryZ 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 nadph quinone reductase
MLHAJGEM_03131 0.0 nox4 - - C - - - Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
MLHAJGEM_03132 2.5e-131 desR - - K ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, Lux Regulon
MLHAJGEM_03133 4.13e-256 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MLHAJGEM_03134 7.05e-172 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
MLHAJGEM_03135 3.43e-203 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
MLHAJGEM_03137 6.64e-109 - - - K ko:K03827 - ko00000,ko01000 Acetyltransferase (GNAT) domain
MLHAJGEM_03138 4.89e-103 - - - K - - - MarR family
MLHAJGEM_03139 1.42e-144 - - - S - - - Psort location CytoplasmicMembrane, score
MLHAJGEM_03140 4.36e-208 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MLHAJGEM_03141 2.02e-168 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
MLHAJGEM_03142 5.21e-254 - - - - - - - -
MLHAJGEM_03143 8.31e-253 - - - - - - - -
MLHAJGEM_03144 7.01e-213 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MLHAJGEM_03145 1.18e-85 ytrA - - K ko:K07979 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
MLHAJGEM_03146 1.74e-251 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MLHAJGEM_03147 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MLHAJGEM_03148 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
MLHAJGEM_03149 8.64e-224 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
MLHAJGEM_03150 2.84e-189 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
MLHAJGEM_03151 2.27e-216 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MLHAJGEM_03152 1.15e-94 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
MLHAJGEM_03153 7.7e-110 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MLHAJGEM_03154 4.81e-229 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
MLHAJGEM_03155 9.21e-94 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
MLHAJGEM_03156 1.09e-30 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
MLHAJGEM_03157 2.32e-194 yqfL 2.7.11.33, 2.7.4.28 - F ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MLHAJGEM_03158 4.26e-165 - - - C - - - Enoyl-(Acyl carrier protein) reductase
MLHAJGEM_03159 1.42e-217 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MLHAJGEM_03160 1.84e-284 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MLHAJGEM_03161 4.35e-204 yitT - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
MLHAJGEM_03162 2.61e-132 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MLHAJGEM_03163 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
MLHAJGEM_03164 2.47e-310 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
MLHAJGEM_03165 4.01e-200 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 N-acetylmuramoyl-L-alanine amidase
MLHAJGEM_03166 2.97e-210 - - - G - - - Fructosamine kinase
MLHAJGEM_03167 2.73e-147 yjcF - - J - - - HAD-hyrolase-like
MLHAJGEM_03168 8.2e-102 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MLHAJGEM_03169 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MLHAJGEM_03170 8.61e-75 - - - - - - - -
MLHAJGEM_03171 3.13e-172 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MLHAJGEM_03172 2.04e-226 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
MLHAJGEM_03173 5.28e-146 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
MLHAJGEM_03174 4.78e-65 - - - - - - - -
MLHAJGEM_03175 1.73e-67 - - - - - - - -
MLHAJGEM_03178 4.1e-158 int7 - - L - - - Belongs to the 'phage' integrase family
MLHAJGEM_03179 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MLHAJGEM_03180 7.97e-311 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MLHAJGEM_03181 5.75e-47 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLHAJGEM_03182 1.14e-297 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
MLHAJGEM_03183 0.0 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLHAJGEM_03184 8.59e-27 dltX - - S - - - D-Ala-teichoic acid biosynthesis protein
MLHAJGEM_03185 1.71e-265 pbpX2 - - V - - - Beta-lactamase
MLHAJGEM_03186 2.54e-266 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MLHAJGEM_03187 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
MLHAJGEM_03188 1.72e-115 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MLHAJGEM_03189 4.42e-248 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MLHAJGEM_03190 2.06e-170 budA 4.1.1.5 - Q ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
MLHAJGEM_03191 2.64e-242 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
MLHAJGEM_03192 6.29e-221 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MLHAJGEM_03193 1.45e-114 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MLHAJGEM_03194 4.22e-246 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
MLHAJGEM_03195 2.01e-303 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MLHAJGEM_03196 9.84e-123 - - - - - - - -
MLHAJGEM_03197 2.58e-275 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MLHAJGEM_03198 0.0 - - - G - - - Major Facilitator
MLHAJGEM_03199 1.76e-70 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MLHAJGEM_03200 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MLHAJGEM_03201 3.28e-63 ylxQ - - J - - - ribosomal protein
MLHAJGEM_03202 2.95e-65 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
MLHAJGEM_03203 4.46e-275 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
MLHAJGEM_03204 9.74e-108 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
MLHAJGEM_03205 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)