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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HKNOCMOD_00001	8.11e-24	-	-	-	T	-	-	-	pathogenesis
HKNOCMOD_00002	2.34e-58	-	-	-	F	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
HKNOCMOD_00003	2.31e-33	-	-	-	F	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
HKNOCMOD_00004	2.4e-173	-	-	-	S	-	-	-	peptidoglycan biosynthetic process
HKNOCMOD_00005	1.85e-206	-	1.4.1.16	-	S	ko:K03340	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
HKNOCMOD_00007	0.000297	-	-	-	S	-	-	-	Entericidin EcnA/B family
HKNOCMOD_00008	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HKNOCMOD_00009	9.06e-135	metF	1.5.1.20	-	E	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	5,10-methylenetetrahydrofolate reductase
HKNOCMOD_00010	7.12e-152	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HKNOCMOD_00011	9.28e-91	queH	1.17.99.6	-	C	ko:K09765	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HKNOCMOD_00012	2.31e-232	-	-	-	S	ko:K07192	ko04910,map04910	ko00000,ko00001,ko03036,ko04131,ko04147	prohibitin homologues
HKNOCMOD_00013	2.13e-118	-	-	-	-	-	-	-	-
HKNOCMOD_00014	0.0	-	-	-	S	ko:K07263	-	ko00000,ko01000,ko01002	Insulinase (Peptidase family M16)
HKNOCMOD_00016	1.99e-49	-	-	-	-	-	-	-	-
HKNOCMOD_00017	1.13e-291	lpxK	2.7.1.130	-	M	ko:K00912	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)
HKNOCMOD_00018	1.52e-137	-	-	-	S	ko:K07164	-	ko00000	C4-type zinc ribbon domain
HKNOCMOD_00020	5.06e-261	-	3.1.13.5	-	J	ko:K03684	-	ko00000,ko01000,ko03016	3'-5' exonuclease
HKNOCMOD_00021	1.5e-74	-	-	-	-	-	-	-	-
HKNOCMOD_00022	9.78e-190	-	3.6.1.66	-	S	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	MazG nucleotide pyrophosphohydrolase domain
HKNOCMOD_00023	2.92e-70	-	-	-	-	-	-	-	-
HKNOCMOD_00024	1.24e-182	-	-	-	S	-	-	-	competence protein
HKNOCMOD_00025	2.03e-101	-	-	-	S	ko:K07107	-	ko00000,ko01000	Thioesterase-like superfamily
HKNOCMOD_00029	2.58e-69	-	-	-	MP	-	-	-	regulation of cell-substrate adhesion
HKNOCMOD_00043	1.4e-20	-	-	-	N	-	-	-	mRNA binding
HKNOCMOD_00044	6.24e-55	-	-	-	K	ko:K07726	-	ko00000,ko03000	sequence-specific DNA binding
HKNOCMOD_00047	0.0	-	3.1.6.1	-	P	ko:K01130	ko00140,ko00600,map00140,map00600	ko00000,ko00001,ko01000	Sulfatase
HKNOCMOD_00048	1.3e-143	-	-	-	-	-	-	-	-
HKNOCMOD_00049	9.08e-165	-	-	-	NU	-	-	-	Prokaryotic N-terminal methylation motif
HKNOCMOD_00050	1.96e-177	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HKNOCMOD_00051	9.73e-294	-	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	16S rRNA methyltransferase RsmB/F
HKNOCMOD_00052	2.86e-114	-	3.1.6.8	-	P	ko:K01134	ko00600,ko04142,map00600,map04142	ko00000,ko00001,ko01000	COG3119 Arylsulfatase A
HKNOCMOD_00053	2.9e-316	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Arginosuccinate synthase
HKNOCMOD_00055	2.79e-54	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HKNOCMOD_00056	8.43e-59	-	-	-	S	-	-	-	Zinc ribbon domain
HKNOCMOD_00057	4.77e-310	-	-	-	S	-	-	-	PFAM CBS domain containing protein
HKNOCMOD_00058	2.51e-151	-	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HII
HKNOCMOD_00059	4.83e-82	-	-	-	L	ko:K07460	-	ko00000	Uncharacterised protein family UPF0102
HKNOCMOD_00061	8.28e-178	-	4.1.1.48	-	E	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Indole-3-glycerol phosphate synthase
HKNOCMOD_00062	3.4e-229	-	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil DNA glycosylase superfamily
HKNOCMOD_00063	1.39e-157	-	-	-	S	-	-	-	3D domain
HKNOCMOD_00064	2.07e-149	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HKNOCMOD_00065	9.91e-171	-	-	-	U	ko:K03561	-	ko00000,ko02000	MotA/TolQ/ExbB proton channel family
HKNOCMOD_00066	9.16e-111	aglS	-	-	U	ko:K03559	-	ko00000,ko02000	biopolymer transport protein
HKNOCMOD_00067	1.24e-98	exbD2	-	-	U	ko:K03559	-	ko00000,ko02000	biopolymer transport protein
HKNOCMOD_00068	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
HKNOCMOD_00069	2.87e-190	-	-	-	-	-	-	-	-
HKNOCMOD_00070	1.43e-273	-	-	-	K	-	-	-	sequence-specific DNA binding
HKNOCMOD_00071	0.0	-	-	-	J	ko:K08301	-	ko00000,ko01000,ko03009,ko03019	Ribonuclease E/G family
HKNOCMOD_00072	5.06e-236	-	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Actin
HKNOCMOD_00073	0.0	lacZ_17	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase activity
HKNOCMOD_00075	1.26e-260	-	-	-	G	-	-	-	M42 glutamyl aminopeptidase
HKNOCMOD_00077	2.51e-175	-	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	CobB/CobQ-like glutamine amidotransferase domain
HKNOCMOD_00078	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate
HKNOCMOD_00079	3.06e-99	-	-	-	-	-	-	-	-
HKNOCMOD_00080	2.21e-165	-	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	SAICAR synthetase
HKNOCMOD_00081	0.0	-	-	-	K	-	-	-	Transcription elongation factor, N-terminal
HKNOCMOD_00082	0.0	-	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HKNOCMOD_00083	1.14e-168	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HKNOCMOD_00084	2.69e-279	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HKNOCMOD_00085	1.42e-205	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
HKNOCMOD_00086	6.39e-200	-	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Serine acetyltransferase, N-terminal
HKNOCMOD_00087	3.57e-108	-	-	-	S	ko:K15977	-	ko00000	DoxX
HKNOCMOD_00088	2.76e-292	-	4.2.1.129, 5.4.99.17	-	I	ko:K06045	ko00909,ko01110,map00909,map01110	ko00000,ko00001,ko01000	PFAM Prenyltransferase squalene oxidase
HKNOCMOD_00089	9.78e-186	-	-	-	-	-	-	-	-
HKNOCMOD_00090	5.13e-219	-	5.3.1.13	-	M	ko:K06041	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	SIS domain
HKNOCMOD_00091	5.04e-181	-	-	-	H	-	-	-	ThiF family
HKNOCMOD_00092	8.92e-111	-	-	-	U	-	-	-	response to pH
HKNOCMOD_00093	4.11e-223	-	-	-	-	-	-	-	-
HKNOCMOD_00094	2.76e-216	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HKNOCMOD_00096	0.0	-	-	-	G	-	-	-	Raffinose synthase or seed imbibition protein Sip1
HKNOCMOD_00097	2.44e-232	-	-	-	S	-	-	-	COGs COG4299 conserved
HKNOCMOD_00098	6.86e-122	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
HKNOCMOD_00099	0.0	-	3.4.16.4	-	M	ko:K05515	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein dimerisation domain
HKNOCMOD_00100	0.0	-	-	-	-	-	-	-	-
HKNOCMOD_00101	7.19e-209	-	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	ATP synthase A chain
HKNOCMOD_00102	1.65e-11	-	-	-	S	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	PFAM H transporting two-sector ATPase C subunit
HKNOCMOD_00103	2.53e-77	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	ATP synthase B/B' CF(0)
HKNOCMOD_00104	6.46e-86	-	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	ATP synthase delta (OSCP) subunit
HKNOCMOD_00105	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HKNOCMOD_00106	1.83e-200	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HKNOCMOD_00107	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HKNOCMOD_00108	9.38e-86	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HKNOCMOD_00109	3.38e-140	-	-	-	-	-	-	-	-
HKNOCMOD_00110	3.8e-124	sprT	-	-	K	-	-	-	SprT-like family
HKNOCMOD_00111	9.26e-270	-	-	-	S	-	-	-	COGs COG4299 conserved
HKNOCMOD_00112	5.4e-285	-	2.6.1.59	-	M	ko:K02805	-	ko00000,ko01000,ko01007	DegT/DnrJ/EryC1/StrS aminotransferase family
HKNOCMOD_00113	2.86e-113	flmH	2.3.1.57	-	J	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	ko00000,ko00001,ko00002,ko01000	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HKNOCMOD_00114	7.63e-220	-	-	-	M	-	-	-	Glycosyl transferase family 2
HKNOCMOD_00115	3.11e-73	-	-	-	P	ko:K03297,ko:K11741	-	ko00000,ko02000	Multidrug Resistance protein
HKNOCMOD_00116	1.93e-77	-	-	-	P	ko:K03297,ko:K11741	-	ko00000,ko02000	Multidrug Resistance protein
HKNOCMOD_00119	1.36e-130	-	-	-	F	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
HKNOCMOD_00120	0.0	-	2.6.1.62	-	H	ko:K00833	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
HKNOCMOD_00121	2.06e-233	-	2.8.1.6	-	H	ko:K01012	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Biotin and Thiamin Synthesis associated domain
HKNOCMOD_00122	0.0	-	-	-	P	-	-	-	Sulfatase
HKNOCMOD_00123	0.0	-	-	-	M	-	-	-	Bacterial membrane protein, YfhO
HKNOCMOD_00124	4.22e-286	-	-	-	O	ko:K09015	-	ko00000	Uncharacterized protein family (UPF0051)
HKNOCMOD_00125	0.0	-	-	-	O	ko:K09014	-	ko00000	Uncharacterized protein family (UPF0051)
HKNOCMOD_00126	1.02e-178	-	-	-	O	ko:K09013	-	ko00000,ko02000	ATPases associated with a variety of cellular activities
HKNOCMOD_00127	6.78e-100	-	-	-	P	ko:K09825	-	ko00000,ko03000	Ferric uptake regulator family
HKNOCMOD_00128	2.14e-57	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L27 protein
HKNOCMOD_00129	1.93e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal prokaryotic L21 protein
HKNOCMOD_00130	5.76e-107	-	-	-	S	ko:K06925	-	ko00000,ko03016	Threonylcarbamoyl adenosine biosynthesis protein TsaE
HKNOCMOD_00131	2.16e-199	-	-	-	S	ko:K06889	-	ko00000	alpha beta
HKNOCMOD_00133	0.0	-	-	-	M	-	-	-	Parallel beta-helix repeats
HKNOCMOD_00134	0.0	-	-	-	-	-	-	-	-
HKNOCMOD_00135	2.58e-225	-	-	-	S	-	-	-	Polyphosphate kinase 2 (PPK2)
HKNOCMOD_00137	1.94e-175	-	-	-	-	-	-	-	-
HKNOCMOD_00138	3.35e-131	-	-	-	L	-	-	-	Conserved hypothetical protein 95
HKNOCMOD_00139	1.95e-308	-	2.4.99.12, 2.4.99.13, 2.4.99.14, 2.4.99.15	GT30	M	ko:K02527	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase)
HKNOCMOD_00140	3.53e-228	-	-	-	S	-	-	-	Aspartyl protease
HKNOCMOD_00141	1.37e-271	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HKNOCMOD_00142	6.55e-155	-	6.3.2.5	-	H	ko:K21977	ko00770,map00770	ko00000,ko00001,ko00002,ko01000	DNA / pantothenate metabolism flavoprotein
HKNOCMOD_00143	1.93e-270	-	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class-V
HKNOCMOD_00146	2.14e-21	-	-	-	K	ko:K03826	-	ko00000,ko01000	acetyltransferase
HKNOCMOD_00147	1.59e-20	-	-	-	K	ko:K03826	-	ko00000,ko01000	acetyltransferase
HKNOCMOD_00148	1.01e-172	-	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
HKNOCMOD_00149	0.0	-	-	-	L	-	-	-	Polyphosphate kinase 2 (PPK2)
HKNOCMOD_00150	0.0	-	-	-	S	-	-	-	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
HKNOCMOD_00151	6.36e-257	-	-	-	M	-	-	-	Peptidase family M23
HKNOCMOD_00153	8.37e-126	-	4.1.1.36	-	H	ko:K01598	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Flavoprotein
HKNOCMOD_00154	1.31e-81	-	-	-	DJ	-	-	-	Addiction module toxin, RelE StbE family
HKNOCMOD_00155	1.11e-206	-	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
HKNOCMOD_00157	1.47e-138	-	-	-	K	ko:K03088	-	ko00000,ko03021	ECF sigma factor
HKNOCMOD_00158	0.0	-	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HKNOCMOD_00159	6.75e-245	-	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	AIR synthase related protein, N-terminal domain
HKNOCMOD_00160	1.15e-99	-	-	-	S	ko:K15977	-	ko00000	DoxX
HKNOCMOD_00161	2.07e-235	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
HKNOCMOD_00162	0.0	-	3.1.1.53	-	E	ko:K05970	-	ko00000,ko01000	Carbohydrate esterase, sialic acid-specific acetylesterase
HKNOCMOD_00163	4.65e-171	-	-	-	-	-	-	-	-
HKNOCMOD_00164	0.0	-	3.6.4.13	-	L	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DbpA RNA binding domain
HKNOCMOD_00165	0.0	-	-	-	P	ko:K01138	-	ko00000,ko01000	PA14 domain
HKNOCMOD_00166	2.16e-150	-	-	-	L	-	-	-	Membrane
HKNOCMOD_00168	0.0	gcvP	1.4.4.2	-	E	ko:K00281	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HKNOCMOD_00169	6.67e-86	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
HKNOCMOD_00170	2.73e-265	gcvT	2.1.2.10	-	E	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Aminomethyltransferase folate-binding domain
HKNOCMOD_00171	4.51e-261	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HKNOCMOD_00172	1e-163	-	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
HKNOCMOD_00173	1.45e-199	-	3.1.26.4	-	L	ko:K03471	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HII
HKNOCMOD_00174	1.9e-62	-	-	-	L	-	-	-	bacterial (prokaryotic) histone like domain
HKNOCMOD_00180	1.43e-142	-	-	-	U	ko:K03561	-	ko00000,ko02000	MotA/TolQ/ExbB proton channel family
HKNOCMOD_00181	3.02e-170	-	2.5.1.39	-	H	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
HKNOCMOD_00182	3.33e-254	-	5.2.1.8	-	O	ko:K03771	-	ko00000,ko01000,ko03110	SurA N-terminal domain
HKNOCMOD_00183	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Domain of unknown function (DUF4982)
HKNOCMOD_00184	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HKNOCMOD_00185	7.23e-202	-	-	-	-	-	-	-	-
HKNOCMOD_00186	6.79e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HKNOCMOD_00187	2.19e-56	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HKNOCMOD_00188	5.78e-35	-	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L29 protein
HKNOCMOD_00189	3.42e-97	-	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HKNOCMOD_00190	4.27e-155	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HKNOCMOD_00191	4.97e-70	-	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome
HKNOCMOD_00192	4.05e-152	-	-	-	-	-	-	-	-
HKNOCMOD_00193	1.05e-58	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HKNOCMOD_00194	1.85e-203	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HKNOCMOD_00195	8.72e-58	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HKNOCMOD_00196	9.43e-132	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L4/L1 family
HKNOCMOD_00197	2.24e-148	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HKNOCMOD_00198	3.67e-65	-	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S10p/S20e
HKNOCMOD_00199	0.0	-	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HKNOCMOD_00200	2.91e-104	-	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S7p/S5e
HKNOCMOD_00201	4.16e-85	-	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S12/S23
HKNOCMOD_00202	0.0	gpmI	5.4.2.12	-	G	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	BPG-independent PGAM N-terminus (iPGM_N)
HKNOCMOD_00203	4.61e-95	-	-	-	S	ko:K07107	-	ko00000,ko01000	Thioesterase superfamily
HKNOCMOD_00204	1.49e-273	-	-	-	T	-	-	-	PAS domain
HKNOCMOD_00205	0.0	-	-	-	T	-	-	-	Bacterial regulatory protein, Fis family
HKNOCMOD_00206	0.0	-	-	-	O	-	-	-	C-terminal four TMM region of protein-O-mannosyltransferase
HKNOCMOD_00207	3.08e-52	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease VII activity
HKNOCMOD_00208	0.0	dxs	2.2.1.7	-	HI	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HKNOCMOD_00209	6.61e-182	-	-	-	S	-	-	-	Tetratricopeptide repeat
HKNOCMOD_00210	2.6e-124	-	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Recombination protein O N terminal
HKNOCMOD_00211	9.26e-249	-	-	-	S	ko:K07091	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Predicted permease YjgP/YjgQ family
HKNOCMOD_00212	0.0	der	-	-	S	ko:K03977	-	ko00000,ko03009	KH-domain-like of EngA bacterial GTPase enzymes, C-terminal
HKNOCMOD_00213	2.39e-228	-	-	-	EP	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
HKNOCMOD_00214	4.51e-148	cat	2.3.1.28	-	V	ko:K19271	-	br01600,ko00000,ko01000,ko01504	Chloramphenicol acetyltransferase
HKNOCMOD_00215	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HKNOCMOD_00216	3.5e-168	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HKNOCMOD_00217	0.0	-	-	-	P	ko:K02014	-	ko00000,ko02000	TonB dependent receptor
HKNOCMOD_00218	2.1e-203	-	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydrogenase
HKNOCMOD_00220	0.0	-	-	-	EGIP	-	-	-	Phosphate acyltransferases
HKNOCMOD_00221	9.82e-111	-	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	Cytidine and deoxycytidylate deaminase zinc-binding region
HKNOCMOD_00223	2.44e-90	-	-	-	O	-	-	-	OsmC-like protein
HKNOCMOD_00224	0.0	-	-	-	CO	-	-	-	Disulphide bond corrector protein DsbC
HKNOCMOD_00225	2.19e-164	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HKNOCMOD_00226	7.28e-138	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Exonuclease
HKNOCMOD_00227	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HKNOCMOD_00228	4.69e-79	rsfS	-	-	S	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HKNOCMOD_00229	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HKNOCMOD_00231	1.29e-257	-	-	-	S	-	-	-	AAA domain, putative AbiEii toxin, Type IV TA system
HKNOCMOD_00232	2.59e-198	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Enoyl-CoA hydratase/isomerase
HKNOCMOD_00235	2.07e-299	-	-	-	MU	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	efflux transmembrane transporter activity
HKNOCMOD_00239	9.45e-145	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
HKNOCMOD_00242	0.0	-	-	-	V	-	-	-	ABC-2 type transporter
HKNOCMOD_00243	8.38e-98	-	-	-	-	-	-	-	-
HKNOCMOD_00244	2.65e-184	-	-	-	S	ko:K07124	-	ko00000	Enoyl-(Acyl carrier protein) reductase
HKNOCMOD_00245	0.0	-	-	-	S	-	-	-	Fungal chitosanase of glycosyl hydrolase group 75
HKNOCMOD_00246	9.28e-219	-	2.5.1.21	-	I	ko:K00801	ko00100,ko00909,ko01100,ko01110,ko01130,map00100,map00909,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko01006	Squalene/phytoene synthase
HKNOCMOD_00247	0.0	-	-	-	KT	ko:K02584	ko02020,map02020	ko00000,ko00001,ko03000	Bacterial regulatory protein, Fis family
HKNOCMOD_00248	0.0	-	-	-	P	ko:K03281	-	ko00000	Voltage gated chloride channel
HKNOCMOD_00250	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	PFAM Glycoside hydrolase, family 20, catalytic core
HKNOCMOD_00252	0.0	-	-	-	-	-	-	-	-
HKNOCMOD_00253	0.0	-	4.1.1.15	-	E	ko:K01580	ko00250,ko00410,ko00430,ko00650,ko01100,ko01110,ko01120,ko02024,ko04727,ko04940,map00250,map00410,map00430,map00650,map01100,map01110,map01120,map02024,map04727,map04940	ko00000,ko00001,ko00002,ko01000	Pyridoxal-dependent decarboxylase conserved domain
HKNOCMOD_00254	1.74e-140	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HKNOCMOD_00255	0.0	-	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase alpha chain like domain
HKNOCMOD_00256	2.02e-236	pyrD	1.3.5.2	-	F	ko:K00254	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Dihydroorotate dehydrogenase
HKNOCMOD_00257	2.72e-155	-	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Thiamine monophosphate synthase
HKNOCMOD_00258	1.29e-158	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKNOCMOD_00259	2.31e-164	-	-	-	CO	-	-	-	Thioredoxin-like
HKNOCMOD_00260	0.0	-	-	-	C	-	-	-	Cytochrome c554 and c-prime
HKNOCMOD_00261	1.27e-306	-	-	-	S	-	-	-	PFAM CBS domain containing protein
HKNOCMOD_00262	9.05e-313	tlyC	-	-	S	ko:K03699	-	ko00000,ko02042	PFAM CBS domain containing protein
HKNOCMOD_00263	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HKNOCMOD_00264	3.01e-49	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal_S15
HKNOCMOD_00265	8.44e-154	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HKNOCMOD_00266	2.46e-215	-	-	-	D	ko:K19234,ko:K19236	ko01503,map01503	ko00000,ko00001,ko01002,ko01011	ErfK ybiS ycfS ynhG family protein
HKNOCMOD_00267	0.0	-	-	-	S	-	-	-	Terminase
HKNOCMOD_00270	7.54e-201	-	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HKNOCMOD_00271	2.56e-145	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HKNOCMOD_00272	9.86e-168	-	-	-	M	-	-	-	Peptidase family M23
HKNOCMOD_00273	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	PFAM coagulation factor 5 8 type domain protein
HKNOCMOD_00274	1.33e-174	-	-	-	NU	-	-	-	Prepilin-type N-terminal cleavage methylation domain
HKNOCMOD_00276	2.1e-180	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HKNOCMOD_00277	0.0	-	-	-	S	-	-	-	Type I phosphodiesterase / nucleotide pyrophosphatase
HKNOCMOD_00278	0.0	-	-	-	G	-	-	-	beta-N-acetylhexosaminidase activity
HKNOCMOD_00279	1.15e-151	-	6.3.3.3	-	H	ko:K01935	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	AAA domain
HKNOCMOD_00281	8.41e-202	-	-	-	S	-	-	-	DisA bacterial checkpoint controller nucleotide-binding
HKNOCMOD_00282	5.14e-143	-	-	-	-	-	-	-	-
HKNOCMOD_00283	5.24e-150	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HKNOCMOD_00284	3.42e-196	panC	6.3.2.1	-	H	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HKNOCMOD_00285	1.48e-120	-	-	-	M	ko:K06142	-	ko00000	Outer membrane protein (OmpH-like)
HKNOCMOD_00286	5.68e-188	lpxD	2.3.1.191	-	M	ko:K02536	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HKNOCMOD_00287	4.89e-196	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKNOCMOD_00288	4.68e-189	-	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HKNOCMOD_00289	7.38e-252	-	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	NMT1/THI5 like
HKNOCMOD_00291	9.8e-223	hyl	2.3.1.48, 3.2.1.169, 3.2.1.35	GH84	G	ko:K01197,ko:K15719	ko00531,ko01100,ko04931,map00531,map01100,map04931	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	beta-N-acetylhexosaminidase activity
HKNOCMOD_00292	1.03e-116	-	3.1.3.82, 3.1.3.83	-	E	ko:K03273	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Polynucleotide kinase 3 phosphatase
HKNOCMOD_00293	8.25e-131	-	5.3.1.28	-	G	ko:K03271	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	SIS domain
HKNOCMOD_00294	0.0	-	2.7.1.167, 2.7.7.70	-	M	ko:K03272	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	pfkB family carbohydrate kinase
HKNOCMOD_00295	1.06e-44	-	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S21
HKNOCMOD_00296	6.33e-313	hemL	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
HKNOCMOD_00297	5.91e-260	-	-	-	S	-	-	-	ankyrin repeats
HKNOCMOD_00298	0.0	-	-	-	EGP	-	-	-	Sugar (and other) transporter
HKNOCMOD_00299	0.0	-	-	-	-	-	-	-	-
HKNOCMOD_00300	0.0	glnS	6.1.1.18	-	J	ko:K01886	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class I (E and Q), anti-codon binding domain
HKNOCMOD_00301	5.32e-285	-	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase II
HKNOCMOD_00302	7.87e-100	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HKNOCMOD_00303	5.63e-197	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HKNOCMOD_00304	5.16e-187	-	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	SRP54-type protein, GTPase domain
HKNOCMOD_00305	1.33e-255	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Elongator protein 3, MiaB family, Radical SAM
HKNOCMOD_00306	0.0	-	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	DnaB-like helicase C terminal domain
HKNOCMOD_00308	2.21e-14	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
HKNOCMOD_00309	1.78e-97	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HKNOCMOD_00310	1.13e-172	-	-	-	S	-	-	-	Lysin motif
HKNOCMOD_00311	8.25e-131	-	-	-	-	-	-	-	-
HKNOCMOD_00312	8.56e-45	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Phosphopantetheine attachment site
HKNOCMOD_00313	5.89e-173	coaX	2.7.1.33	-	K	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Type III pantothenate kinase
HKNOCMOD_00314	1.16e-264	-	-	-	M	-	-	-	Monogalactosyldiacylglycerol (MGDG) synthase
HKNOCMOD_00315	2.62e-225	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HKNOCMOD_00316	0.0	-	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	UvrD-like helicase C-terminal domain
HKNOCMOD_00318	0.0	-	-	-	S	ko:K03307	-	ko00000	Sodium:solute symporter family
HKNOCMOD_00319	1.04e-282	-	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Galactokinase galactose-binding signature
HKNOCMOD_00320	0.0	-	-	-	M	-	-	-	Bacterial sugar transferase
HKNOCMOD_00321	8.19e-140	-	-	-	S	-	-	-	RNA recognition motif
HKNOCMOD_00322	1.44e-184	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
HKNOCMOD_00323	0.0	-	-	-	-	-	-	-	-
HKNOCMOD_00325	0.0	-	-	-	V	-	-	-	ABC-2 type transporter
HKNOCMOD_00326	0.0	-	-	-	C	-	-	-	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein
HKNOCMOD_00327	5.47e-202	-	-	-	S	-	-	-	Domain of unknown function (DUF362)
HKNOCMOD_00328	1.37e-131	-	-	-	J	-	-	-	Putative rRNA methylase
HKNOCMOD_00329	7.02e-144	-	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HKNOCMOD_00330	3.73e-195	-	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease/Exonuclease/phosphatase family
HKNOCMOD_00331	2.27e-288	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	NusA-like KH domain
HKNOCMOD_00332	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HKNOCMOD_00333	2e-82	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HKNOCMOD_00334	0.0	-	-	-	P	-	-	-	PA14 domain
HKNOCMOD_00335	1.77e-15	-	-	-	-	-	-	-	-
HKNOCMOD_00336	0.0	-	-	-	T	-	-	-	5TM C-terminal transporter carbon starvation CstA
HKNOCMOD_00337	0.0	-	-	-	EGIP	-	-	-	Phosphate acyltransferases
HKNOCMOD_00338	1.11e-132	-	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HKNOCMOD_00339	1.25e-283	-	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HKNOCMOD_00340	1.64e-222	-	-	-	C	-	-	-	e3 binding domain
HKNOCMOD_00341	1.6e-127	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
HKNOCMOD_00342	8.81e-265	-	-	-	S	-	-	-	PFAM glycosyl transferase family 2
HKNOCMOD_00343	2.56e-271	-	-	-	-	-	-	-	-
HKNOCMOD_00344	7.99e-253	-	-	-	S	-	-	-	Glycosyltransferase like family 2
HKNOCMOD_00345	1.77e-225	-	-	-	S	-	-	-	Glycosyl transferase family 11
HKNOCMOD_00346	9.43e-272	-	-	GT2	S	ko:K19427	-	ko00000,ko01000	PFAM glycosyl transferase family 2
HKNOCMOD_00348	2.37e-271	-	-	-	H	-	-	-	PFAM glycosyl transferase family 8
HKNOCMOD_00349	0.0	-	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Polyphosphate kinase middle domain
HKNOCMOD_00350	0.0	-	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	Ppx/GppA phosphatase family
HKNOCMOD_00351	3.55e-258	-	-	-	S	ko:K11941	-	ko00000,ko01000	transferase activity, transferring acyl groups other than amino-acyl groups
HKNOCMOD_00352	7.48e-192	map	3.4.11.18	-	J	ko:K01265	-	ko00000,ko01000,ko01002	Metallopeptidase family M24
HKNOCMOD_00353	1.76e-152	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HKNOCMOD_00354	0.0	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HKNOCMOD_00356	6.42e-101	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A
HKNOCMOD_00357	3.38e-102	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HKNOCMOD_00358	6.82e-74	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HKNOCMOD_00359	9.16e-105	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HKNOCMOD_00360	4.08e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HKNOCMOD_00361	5.36e-138	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HKNOCMOD_00362	1.53e-47	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal proteins 50S L24/mitochondrial 39S L24
HKNOCMOD_00363	2.33e-205	nadK	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HKNOCMOD_00364	2.07e-123	-	-	-	M	ko:K03642	-	ko00000	Lytic transglycolase
HKNOCMOD_00365	0.0	-	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
HKNOCMOD_00366	0.0	-	2.7.11.1	-	L	ko:K08282	-	ko00000,ko01000	SNF2 Helicase protein
HKNOCMOD_00367	0.0	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HKNOCMOD_00369	3.03e-277	-	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Mur ligase middle domain
HKNOCMOD_00370	0.0	-	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Collagenase
HKNOCMOD_00371	2.4e-23	-	-	-	M	ko:K13730	ko05100,map05100	ko00000,ko00001	leucine-rich repeat-containing protein typical subtype
HKNOCMOD_00372	2.93e-181	-	-	-	I	-	-	-	Acyl-ACP thioesterase
HKNOCMOD_00373	8.15e-229	-	4.1.1.35	-	M	ko:K08678	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko00002,ko01000	3-beta hydroxysteroid dehydrogenase/isomerase family
HKNOCMOD_00374	0.0	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
HKNOCMOD_00375	1.95e-158	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
HKNOCMOD_00377	4.89e-237	-	4.2.1.24	-	H	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko04147	Delta-aminolevulinic acid dehydratase
HKNOCMOD_00379	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HKNOCMOD_00380	3.29e-146	-	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HKNOCMOD_00382	1.39e-276	-	-	-	S	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
HKNOCMOD_00383	4.4e-268	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
HKNOCMOD_00384	1.47e-121	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HKNOCMOD_00385	9.23e-63	-	-	-	J	-	-	-	RF-1 domain
HKNOCMOD_00386	2.35e-114	-	-	-	-	-	-	-	-
HKNOCMOD_00387	0.0	-	2.7.7.9	-	G	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP--glucose-1-phosphate uridylyltransferase
HKNOCMOD_00388	1.51e-182	-	2.1.1.144, 2.1.1.197	-	FG	ko:K00598,ko:K02169	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	trans-aconitate 2-methyltransferase activity
HKNOCMOD_00390	9.47e-130	-	-	-	S	-	-	-	protein trimerization
HKNOCMOD_00391	2.15e-218	-	-	-	M	ko:K07271	-	ko00000,ko01000	LICD family
HKNOCMOD_00392	0.0	-	2.7.7.15	-	H	ko:K00968	ko00440,ko00564,ko01100,ko05231,map00440,map00564,map01100,map05231	ko00000,ko00001,ko00002,ko01000	Oxidoreductase family, NAD-binding Rossmann fold
HKNOCMOD_00393	2.13e-95	-	4.3.1.12	-	E	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	ko00000,ko00001,ko01000	Ornithine cyclodeaminase/mu-crystallin family
HKNOCMOD_00394	0.0	cobD	2.6.1.9, 2.7.7.74, 4.1.1.81	-	M	ko:K00817,ko:K04720,ko:K07281	ko00340,ko00350,ko00360,ko00400,ko00401,ko00562,ko00860,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00562,map00860,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	nucleotidyl transferase
HKNOCMOD_00395	1.37e-225	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycoside hydrolase, family 20, catalytic core
HKNOCMOD_00396	1.48e-264	-	-	-	I	-	-	-	Prenyltransferase and squalene oxidase repeat
HKNOCMOD_00399	4.18e-178	-	-	-	C	-	-	-	Cytochrome c7 and related cytochrome c
HKNOCMOD_00400	1.44e-313	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HKNOCMOD_00402	1.9e-256	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Iron-containing alcohol dehydrogenase
HKNOCMOD_00410	3.07e-146	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
HKNOCMOD_00411	1.3e-273	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
HKNOCMOD_00413	2.93e-282	-	-	-	S	-	-	-	very-long-chain-acyl-CoA dehydrogenase activity
HKNOCMOD_00414	1.19e-92	-	5.1.3.29	-	G	ko:K02431	-	ko00000,ko01000	RbsD / FucU transport protein family
HKNOCMOD_00415	2.49e-299	-	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase class I and II
HKNOCMOD_00416	0.0	-	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class I (C) catalytic domain
HKNOCMOD_00417	0.0	menD	2.2.1.9	-	H	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HKNOCMOD_00418	1.24e-315	-	1.1.1.40	-	C	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Malic enzyme, NAD binding domain
HKNOCMOD_00419	0.0	-	-	-	I	ko:K06889,ko:K09914	-	ko00000	PFAM Prenyltransferase squalene oxidase
HKNOCMOD_00420	1.44e-222	exsH	3.2.1.178, 3.2.1.18, 3.2.1.52	GH16,GH20,GH33	G	ko:K01186,ko:K12373,ko:K20830	ko00511,ko00513,ko00520,ko00531,ko00600,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00600,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko02042,ko03110	xyloglucan:xyloglucosyl transferase activity
HKNOCMOD_00421	0.0	XK27_03440	3.1.21.5	-	L	ko:K01156	-	ko00000,ko01000,ko02048	Type III restriction
HKNOCMOD_00422	5.36e-224	-	2.1.1.72, 3.1.21.5	-	L	ko:K01156,ko:K07316	-	ko00000,ko01000,ko02048	PFAM DNA methylase N-4 N-6 domain protein
HKNOCMOD_00423	4.21e-165	-	-	-	-	-	-	-	-
HKNOCMOD_00424	5.85e-87	-	-	-	S	-	-	-	Domain of unknown function (DUF4391)
HKNOCMOD_00425	0.0	-	-	-	L	-	-	-	helicase
HKNOCMOD_00426	9.3e-249	-	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Glycosyl hydrolase family 3 N terminal domain
HKNOCMOD_00427	3.77e-127	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HKNOCMOD_00428	3.72e-158	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
HKNOCMOD_00429	0.0	yidC	-	-	O	ko:K03217,ko:K06872	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	serine-type endopeptidase activity
HKNOCMOD_00430	2.22e-238	-	-	-	H	-	-	-	Elongator protein 3, MiaB family, Radical SAM
HKNOCMOD_00435	1.47e-19	-	-	-	H	-	-	-	Elongator protein 3, MiaB family, Radical SAM
HKNOCMOD_00437	4.98e-310	-	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Seryl-tRNA synthetase N-terminal domain
HKNOCMOD_00438	5.79e-274	-	-	-	E	-	-	-	Alcohol dehydrogenase GroES-like domain
HKNOCMOD_00440	7.05e-216	-	3.5.1.53	-	K	ko:K12251	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
HKNOCMOD_00441	1.82e-229	-	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
HKNOCMOD_00442	1.53e-213	-	-	-	S	-	-	-	Protein of unknown function DUF58
HKNOCMOD_00443	2.63e-135	-	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	Peptidyl-tRNA hydrolase
HKNOCMOD_00444	0.0	-	-	-	M	-	-	-	Transglycosylase
HKNOCMOD_00445	0.0	-	3.4.24.3	-	NU	ko:K01387	-	ko00000,ko01000,ko01002,ko02042	translation initiation factor activity
HKNOCMOD_00446	0.0	-	-	-	H	-	-	-	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HKNOCMOD_00447	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HKNOCMOD_00449	0.0	-	-	-	M	ko:K07267	-	ko00000,ko02000	wide pore channel activity
HKNOCMOD_00450	1.4e-297	-	1.12.99.6	-	C	ko:K06282	ko00633,ko01120,map00633,map01120	ko00000,ko00001,ko01000	NiFe/NiFeSe hydrogenase small subunit C-terminal
HKNOCMOD_00451	0.0	-	1.12.99.6	-	C	ko:K06281	ko00633,ko01120,map00633,map01120	ko00000,ko00001,ko01000	Nickel-dependent hydrogenase
HKNOCMOD_00452	1.12e-290	hyaC	-	-	C	ko:K03620	ko02020,map02020	ko00000,ko00001	Prokaryotic cytochrome b561
HKNOCMOD_00453	3.4e-126	-	-	-	C	ko:K03605	-	ko00000,ko01000,ko01002	Hydrogenase maturation protease
HKNOCMOD_00454	2.09e-76	-	-	-	C	ko:K04651	-	ko00000,ko03110	Hydrogenase/urease nickel incorporation, metallochaperone, hypA
HKNOCMOD_00456	6.77e-87	-	-	-	S	ko:K09940	-	ko00000	Domain of unknown function (DUF4870)
HKNOCMOD_00457	6.15e-180	-	-	-	M	-	-	-	NLP P60 protein
HKNOCMOD_00458	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycosyl hydrolase family 20, domain 2
HKNOCMOD_00459	8.43e-155	-	1.5.1.34	-	C	ko:K10679	ko00633,ko01120,map00633,map01120	ko00000,ko00001,ko01000	Nitroreductase family
HKNOCMOD_00460	5.93e-261	-	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
HKNOCMOD_00464	0.0	secD	-	-	U	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HKNOCMOD_00465	1.05e-250	-	-	-	S	ko:K11941	-	ko00000,ko01000	transferase activity, transferring acyl groups other than amino-acyl groups
HKNOCMOD_00466	1.02e-23	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
HKNOCMOD_00470	0.0	-	-	-	M	-	-	-	pathogenesis
HKNOCMOD_00472	2.15e-264	-	-	GT4	M	ko:K16703	-	ko00000,ko01000,ko01003	transferase activity, transferring glycosyl groups
HKNOCMOD_00478	9.28e-149	-	-	-	M	ko:K17733	-	ko00000,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
HKNOCMOD_00481	0.0	-	-	-	P	-	-	-	Cation transport protein
HKNOCMOD_00482	7.11e-300	-	-	-	V	ko:K03327	-	ko00000,ko02000	drug transmembrane transporter activity
HKNOCMOD_00483	3.17e-121	-	-	-	-	-	-	-	-
HKNOCMOD_00484	9.86e-54	-	-	-	-	-	-	-	-
HKNOCMOD_00485	1.45e-102	-	-	-	-	-	-	-	-
HKNOCMOD_00486	0.0	-	2.1.1.182	-	IJ	ko:K02528	-	ko00000,ko01000,ko03009	Ribosomal RNA adenine dimethylases
HKNOCMOD_00487	1.26e-247	-	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	NmrA-like family
HKNOCMOD_00493	3.18e-18	-	-	-	S	-	-	-	Bacteriophage head to tail connecting protein
HKNOCMOD_00495	1.19e-128	-	-	-	S	-	-	-	Glycosyl hydrolase 108
HKNOCMOD_00501	4.77e-258	-	-	-	L	ko:K07445	-	ko00000	Protein of unknown function (DUF1156)
HKNOCMOD_00502	0.0	-	-	-	L	-	-	-	SNF2 family N-terminal domain
HKNOCMOD_00503	1.35e-142	-	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	CDP-alcohol phosphatidyltransferase
HKNOCMOD_00504	0.0	-	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HKNOCMOD_00505	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
HKNOCMOD_00506	3.98e-277	-	4.2.1.51, 5.4.99.5	-	E	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Chorismate mutase type II
HKNOCMOD_00507	6.17e-236	-	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HKNOCMOD_00508	5.05e-187	-	-	-	S	-	-	-	NIF3 (NGG1p interacting factor 3)
HKNOCMOD_00509	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4340)
HKNOCMOD_00510	0.0	-	-	-	N	-	-	-	ABC-type uncharacterized transport system
HKNOCMOD_00511	2.91e-182	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HKNOCMOD_00512	1.81e-222	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HKNOCMOD_00513	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HKNOCMOD_00514	3.19e-115	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	nUDIX hydrolase
HKNOCMOD_00517	7.22e-251	-	2.3.1.1	-	E	ko:K14682	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Acetyltransferase (GNAT) family
HKNOCMOD_00518	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HKNOCMOD_00519	0.0	-	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HKNOCMOD_00521	2.38e-173	-	6.3.5.11, 6.3.5.9	-	V	ko:K02224,ko:K18554	ko00860,ko01100,ko01120,map00860,map01100,map01120	br01600,ko00000,ko00001,ko01000,ko01504	Chloramphenicol phosphotransferase-like protein
HKNOCMOD_00522	6.46e-83	-	-	-	K	ko:K07343	-	ko00000	positive regulation of type IV pilus biogenesis
HKNOCMOD_00523	1.59e-223	-	-	-	CO	-	-	-	Redoxin
HKNOCMOD_00524	1.73e-123	paiA	-	-	K	-	-	-	acetyltransferase
HKNOCMOD_00525	6.52e-216	-	-	-	K	-	-	-	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen
HKNOCMOD_00527	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl tRNA synthetase N terminal dom
HKNOCMOD_00530	0.0	-	3.4.24.70	-	E	ko:K01414	-	ko00000,ko01000,ko01002	Peptidase family M3
HKNOCMOD_00531	0.0	-	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
HKNOCMOD_00532	3.11e-05	-	-	-	-	-	-	-	-
HKNOCMOD_00533	0.0	-	-	-	G	-	-	-	Glycosyl hydrolases family 18
HKNOCMOD_00534	0.0	-	-	-	S	ko:K07126,ko:K13582	ko04112,map04112	ko00000,ko00001	beta-lactamase activity
HKNOCMOD_00536	4.14e-279	-	6.2.1.26	-	IQ	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	AMP-binding enzyme
HKNOCMOD_00537	1.27e-70	-	-	-	K	-	-	-	ribonuclease III activity
HKNOCMOD_00538	1.14e-166	-	-	-	-	-	-	-	-
HKNOCMOD_00539	2.1e-140	nuoC	1.6.5.3	-	C	ko:K00332	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HKNOCMOD_00540	6.52e-139	nuoB	1.6.5.3	-	C	ko:K00331	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HKNOCMOD_00544	1.84e-56	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
HKNOCMOD_00547	9.87e-06	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HKNOCMOD_00548	3.02e-122	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
HKNOCMOD_00558	7.48e-22	-	-	-	OU	-	-	-	Serine dehydrogenase proteinase
HKNOCMOD_00562	2.75e-71	-	-	-	S	-	-	-	Phage terminase large subunit (GpA)
HKNOCMOD_00565	8.2e-08	-	-	-	N	-	-	-	HicA toxin of bacterial toxin-antitoxin,
HKNOCMOD_00566	2.61e-18	-	-	-	N	-	-	-	PFAM Uncharacterised protein family UPF0150
HKNOCMOD_00570	2.26e-84	-	2.1.1.72	-	L	ko:K06223	ko03430,map03430	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	D12 class N6 adenine-specific DNA methyltransferase
HKNOCMOD_00579	9.55e-242	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HKNOCMOD_00580	2.63e-208	-	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Polyprenyl synthetase
HKNOCMOD_00581	1.7e-199	-	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Quinolinate phosphoribosyl transferase, N-terminal domain
HKNOCMOD_00582	1.41e-156	-	1.4.3.5	-	H	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)
HKNOCMOD_00583	2.98e-212	-	5.1.3.15	-	G	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Aldose 1-epimerase
HKNOCMOD_00584	0.0	-	-	-	G	-	-	-	Trehalase
HKNOCMOD_00585	0.0	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HKNOCMOD_00586	4.09e-90	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HKNOCMOD_00587	0.0	glnA	6.3.1.2	-	S	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HKNOCMOD_00588	1.1e-34	-	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L34
HKNOCMOD_00589	1.41e-75	-	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	Ribonuclease P
HKNOCMOD_00590	4.61e-61	-	-	-	S	ko:K08998	-	ko00000	Haemolytic
HKNOCMOD_00591	0.0	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins
HKNOCMOD_00592	0.0	-	1.4.1.13, 1.4.1.14	-	E	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	GXGXG motif
HKNOCMOD_00593	0.0	glnA	6.3.1.2	-	S	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HKNOCMOD_00594	0.0	-	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase large chain, oligomerisation domain
HKNOCMOD_00595	1.09e-272	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase small chain, CPSase domain
HKNOCMOD_00596	6.96e-265	-	4.2.1.47	-	M	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
HKNOCMOD_00597	2.96e-265	fcl	1.1.1.271	-	GM	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction
HKNOCMOD_00598	2.4e-295	-	-	-	C	-	-	-	Na+/H+ antiporter family
HKNOCMOD_00599	1.01e-276	-	-	-	-	-	-	-	-
HKNOCMOD_00600	1.49e-223	-	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphomannose isomerase type I
HKNOCMOD_00601	1.29e-181	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	PFAM N-acetylmuramoyl-L-alanine amidase family 2
HKNOCMOD_00602	7.54e-115	ispF	4.6.1.12	-	I	ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HKNOCMOD_00603	3.37e-181	-	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase family
HKNOCMOD_00604	0.0	-	-	-	M	-	-	-	PFAM glycosyl transferase family 51
HKNOCMOD_00605	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
HKNOCMOD_00606	1.11e-81	-	-	-	U	ko:K03559	-	ko00000,ko02000	Biopolymer transport protein ExbD/TolR
HKNOCMOD_00607	2.47e-180	-	-	-	U	ko:K03561	-	ko00000,ko02000	MotA/TolQ/ExbB proton channel family
HKNOCMOD_00608	0.0	-	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HKNOCMOD_00609	1.04e-98	-	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Predicted SPOUT methyltransferase
HKNOCMOD_00610	4.8e-86	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S9/S16
HKNOCMOD_00611	1.14e-96	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HKNOCMOD_00612	6.12e-40	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HKNOCMOD_00613	0.0	nnrD	4.2.1.136, 5.1.99.6	-	G	ko:K17758,ko:K17759	-	ko00000,ko01000	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HKNOCMOD_00614	1.62e-172	-	-	-	L	ko:K03630	-	ko00000	RadC-like JAB domain
HKNOCMOD_00616	4.03e-174	-	-	-	D	-	-	-	Phage-related minor tail protein
HKNOCMOD_00618	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HKNOCMOD_00619	1.13e-60	-	-	-	L	ko:K09747	-	ko00000	YbaB/EbfC DNA-binding family
HKNOCMOD_00620	1e-248	-	-	-	N	ko:K18353	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01504	Endonuclease Exonuclease Phosphatase
HKNOCMOD_00621	0.0	-	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	DHHA2
HKNOCMOD_00623	1.57e-188	-	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Orotidine 5'-phosphate decarboxylase / HUMPS family
HKNOCMOD_00624	0.0	-	-	-	S	-	-	-	OPT oligopeptide transporter protein
HKNOCMOD_00626	0.0	-	-	-	G	-	-	-	Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain
HKNOCMOD_00627	5.5e-176	-	-	-	-	-	-	-	-
HKNOCMOD_00628	0.0	-	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase alpha chain
HKNOCMOD_00629	7.15e-221	-	1.8.1.9	-	O	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Pyridine nucleotide-disulphide oxidoreductase
HKNOCMOD_00630	1.73e-218	-	-	-	E	ko:K00612	-	ko00000,ko01000	lipolytic protein G-D-S-L family
HKNOCMOD_00632	6.35e-132	panZ	-	-	K	-	-	-	-acetyltransferase
HKNOCMOD_00635	4.58e-182	-	-	-	U	ko:K20276	ko02024,map02024	ko00000,ko00001	domain, Protein
HKNOCMOD_00636	1.85e-149	-	-	-	O	-	-	-	methyltransferase activity
HKNOCMOD_00637	1.55e-284	-	3.5.1.42	-	S	ko:K03742	ko00760,map00760	ko00000,ko00001,ko01000	Competence-damaged protein
HKNOCMOD_00638	4.93e-314	-	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Pyruvate kinase, barrel domain
HKNOCMOD_00639	1.41e-120	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HKNOCMOD_00642	1.54e-283	-	-	-	S	-	-	-	Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units
HKNOCMOD_00643	0.0	-	1.2.1.88, 1.5.5.2	-	CE	ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko03000	Proline dehydrogenase
HKNOCMOD_00645	1.43e-45	-	-	-	S	-	-	-	R3H domain
HKNOCMOD_00646	0.0	-	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	Catalase
HKNOCMOD_00648	0.0	-	-	-	O	-	-	-	Cytochrome C assembly protein
HKNOCMOD_00649	7.64e-137	rbr	-	-	C	-	-	-	Rubrerythrin
HKNOCMOD_00650	2.76e-147	-	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HKNOCMOD_00652	0.0	-	-	-	D	ko:K03466	-	ko00000,ko03036	Ftsk_gamma
HKNOCMOD_00654	1.01e-209	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycoside hydrolase, family 20, catalytic core
HKNOCMOD_00655	1.21e-241	-	-	-	E	ko:K07588	-	ko00000,ko01000	ArgK protein
HKNOCMOD_00656	2.13e-111	-	-	-	F	ko:K08311	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	NUDIX domain
HKNOCMOD_00657	0.0	sepA	-	-	Q	-	-	-	COG2015, Alkyl sulfatase and related hydrolases
HKNOCMOD_00658	1.06e-116	-	-	-	-	-	-	-	-
HKNOCMOD_00659	3.46e-110	ruvC	3.1.22.4	-	L	ko:K01159	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
HKNOCMOD_00660	3.49e-290	-	-	-	L	-	-	-	helicase superfamily c-terminal domain
HKNOCMOD_00661	3.89e-157	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
HKNOCMOD_00662	6.95e-238	-	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Amidohydrolase
HKNOCMOD_00664	1.56e-103	-	-	-	K	-	-	-	DNA-binding transcription factor activity
HKNOCMOD_00665	6.11e-257	-	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Biotin-lipoyl like
HKNOCMOD_00666	0.0	-	-	-	V	-	-	-	AcrB/AcrD/AcrF family
HKNOCMOD_00667	3.26e-111	-	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Dihydrofolate reductase
HKNOCMOD_00668	5.77e-208	-	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Thymidylate synthase
HKNOCMOD_00669	0.0	-	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Phospholipase D. Active site motifs.
HKNOCMOD_00670	0.0	-	4.1.1.3	-	C	ko:K01571	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	HMGL-like
HKNOCMOD_00672	0.0	-	-	-	V	ko:K03327	-	ko00000,ko02000	MatE
HKNOCMOD_00673	1.01e-254	-	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Iron-sulfur cluster assembly protein
HKNOCMOD_00674	6.78e-42	-	-	-	S	-	-	-	PurA ssDNA and RNA-binding protein
HKNOCMOD_00675	0.0	-	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	LeuA allosteric (dimerisation) domain
HKNOCMOD_00676	0.0	prlC	3.4.24.70	-	E	ko:K01414	-	ko00000,ko01000,ko01002	Peptidase family M3
HKNOCMOD_00677	2.24e-282	-	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HKNOCMOD_00678	0.0	-	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HKNOCMOD_00679	0.0	-	-	-	MU	ko:K18139	ko01501,ko02024,map01501,map02024	ko00000,ko00001,ko00002,ko01504,ko02000	Outer membrane efflux protein
HKNOCMOD_00681	0.0	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
HKNOCMOD_00682	2.63e-149	-	-	-	-	-	-	-	-
HKNOCMOD_00685	1.34e-109	ptsN	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770,ko:K02806	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system
HKNOCMOD_00686	0.0	-	-	-	P	ko:K03281	-	ko00000	Voltage gated chloride channel
HKNOCMOD_00687	2.77e-250	-	-	-	L	-	-	-	Transposase IS200 like
HKNOCMOD_00689	0.0	-	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
HKNOCMOD_00690	2.08e-263	-	2.4.1.182	GT19	M	ko:K00748	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HKNOCMOD_00691	3.89e-149	dedA	-	-	S	-	-	-	FtsZ-dependent cytokinesis
HKNOCMOD_00692	6.7e-119	-	-	-	S	-	-	-	nitrogen fixation
HKNOCMOD_00693	1.08e-76	-	-	-	S	-	-	-	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
HKNOCMOD_00694	3.21e-115	-	-	-	CO	-	-	-	cell redox homeostasis
HKNOCMOD_00696	2.03e-178	-	-	-	-	-	-	-	-
HKNOCMOD_00698	0.0	-	-	-	S	-	-	-	Bacteriophage head to tail connecting protein
HKNOCMOD_00700	3.45e-145	-	-	-	-	-	-	-	-
HKNOCMOD_00701	4.51e-64	-	-	-	K	-	-	-	DNA-binding transcription factor activity
HKNOCMOD_00710	0.0	-	-	-	V	-	-	-	MatE
HKNOCMOD_00711	4.33e-161	menG	2.1.1.163, 2.1.1.201	-	Q	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	ubiE/COQ5 methyltransferase family
HKNOCMOD_00715	5.94e-198	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HKNOCMOD_00716	3.85e-27	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HKNOCMOD_00717	0.0	-	-	-	M	-	-	-	AsmA-like C-terminal region
HKNOCMOD_00718	1.68e-158	-	-	-	S	ko:K06911	-	ko00000	Pirin
HKNOCMOD_00722	4.64e-170	-	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	FtsJ-like methyltransferase
HKNOCMOD_00725	2.83e-173	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HKNOCMOD_00726	5.06e-280	-	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	S-adenosylmethionine-dependent methyltransferase
HKNOCMOD_00727	6.43e-55	-	-	-	S	ko:K06960	-	ko00000	KH domain
HKNOCMOD_00728	0.0	-	-	-	-	-	-	-	-
HKNOCMOD_00729	0.0	-	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	RNA cap guanine-N2 methyltransferase
HKNOCMOD_00730	4.16e-214	-	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
HKNOCMOD_00731	1.84e-238	-	4.2.1.113	-	M	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Mandelate Racemase Muconate Lactonizing
HKNOCMOD_00733	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 20, domain 2
HKNOCMOD_00735	0.0	-	-	-	V	-	-	-	Polysaccharide biosynthesis C-terminal domain
HKNOCMOD_00736	0.0	-	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
HKNOCMOD_00737	1.65e-102	-	-	-	G	-	-	-	single-species biofilm formation
HKNOCMOD_00738	7.97e-113	-	-	-	K	ko:K13640	-	ko00000,ko03000	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
HKNOCMOD_00739	4.8e-128	-	-	-	S	-	-	-	Flavodoxin-like fold
HKNOCMOD_00740	1.11e-188	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Cupin domain
HKNOCMOD_00741	4.01e-100	-	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
HKNOCMOD_00742	9.98e-129	-	-	-	C	-	-	-	FMN binding
HKNOCMOD_00743	3.6e-265	-	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase
HKNOCMOD_00744	1.48e-270	-	-	-	C	-	-	-	Aldo/keto reductase family
HKNOCMOD_00745	1.41e-266	-	-	-	S	ko:K06889	-	ko00000	X-Pro dipeptidyl-peptidase (S15 family)
HKNOCMOD_00746	7.86e-207	-	-	-	S	-	-	-	Aldo/keto reductase family
HKNOCMOD_00747	7.1e-216	-	1.2.7.3	-	-	ko:K00176,ko:K07138	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	br01601,ko00000,ko00001,ko00002,ko01000	-
HKNOCMOD_00748	1.23e-295	-	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase class I and II
HKNOCMOD_00749	1.08e-139	-	-	-	M	-	-	-	polygalacturonase activity
HKNOCMOD_00751	2.71e-191	-	-	-	KT	-	-	-	Peptidase S24-like
HKNOCMOD_00752	4.13e-218	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
HKNOCMOD_00753	1.14e-45	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
HKNOCMOD_00756	6.57e-176	-	-	-	O	-	-	-	Trypsin
HKNOCMOD_00757	2.14e-235	-	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
HKNOCMOD_00758	8.8e-203	-	-	-	-	-	-	-	-
HKNOCMOD_00759	0.0	-	-	-	S	-	-	-	Sulfatase-modifying factor enzyme 1
HKNOCMOD_00760	2.51e-280	-	-	-	S	-	-	-	Tetratricopeptide repeat
HKNOCMOD_00762	2.63e-10	-	-	-	-	-	-	-	-
HKNOCMOD_00764	8.23e-62	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HKNOCMOD_00765	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HKNOCMOD_00766	2.48e-228	-	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
HKNOCMOD_00767	2.96e-209	-	-	-	S	-	-	-	Protein of unknown function DUF58
HKNOCMOD_00768	3.15e-131	-	-	-	-	-	-	-	-
HKNOCMOD_00769	1.33e-228	-	-	-	S	-	-	-	Protein of unknown function (DUF1194)
HKNOCMOD_00775	7e-31	-	-	-	M	-	-	-	lytic transglycosylase activity
HKNOCMOD_00776	5.27e-34	-	-	-	-	-	-	-	-
HKNOCMOD_00777	2.03e-06	-	-	-	L	-	-	-	Excalibur calcium-binding domain
HKNOCMOD_00779	1.58e-12	-	-	-	-	-	-	-	-
HKNOCMOD_00793	0.0	-	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	DNA Topoisomerase IV
HKNOCMOD_00794	5.26e-74	-	-	-	-	-	-	-	-
HKNOCMOD_00796	4.02e-188	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HKNOCMOD_00797	1.93e-313	-	-	-	G	-	-	-	cellulose 1,4-beta-cellobiosidase activity
HKNOCMOD_00798	4.05e-112	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
HKNOCMOD_00800	0.0	-	-	-	P	-	-	-	Domain of unknown function
HKNOCMOD_00801	7.71e-294	-	-	-	S	-	-	-	AI-2E family transporter
HKNOCMOD_00802	0.0	rseP	3.4.21.116	-	M	ko:K06399,ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	metalloendopeptidase activity
HKNOCMOD_00803	2.11e-89	-	-	-	-	-	-	-	-
HKNOCMOD_00804	2.63e-267	-	3.5.3.12	-	E	ko:K10536	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	Porphyromonas-type peptidyl-arginine deiminase
HKNOCMOD_00805	0.0	-	-	-	H	ko:K07137	-	ko00000	5-formyltetrahydrofolate cyclo-ligase activity
HKNOCMOD_00808	3.73e-90	-	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	AIR carboxylase
HKNOCMOD_00809	3.28e-122	-	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Phosphoribosyl transferase domain
HKNOCMOD_00810	1.55e-222	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain
HKNOCMOD_00811	3.91e-306	-	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Dihydro-orotase-like
HKNOCMOD_00812	1.57e-168	-	-	-	S	-	-	-	Uncharacterised protein family UPF0066
HKNOCMOD_00813	2.91e-94	-	-	-	K	-	-	-	DNA-binding transcription factor activity
HKNOCMOD_00814	6.02e-283	mtrC	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HKNOCMOD_00815	0.0	-	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HKNOCMOD_00816	3.71e-283	-	-	-	V	-	-	-	Beta-lactamase
HKNOCMOD_00817	9.1e-317	-	-	-	MU	-	-	-	Outer membrane efflux protein
HKNOCMOD_00818	3.42e-313	-	-	-	V	-	-	-	MacB-like periplasmic core domain
HKNOCMOD_00819	2.12e-162	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HKNOCMOD_00820	4.33e-278	-	-	-	M	ko:K02005	-	ko00000	HlyD family secretion protein
HKNOCMOD_00822	5.75e-98	nudI	3.6.1.55	-	F	ko:K03574,ko:K12944	-	ko00000,ko01000,ko03400	GDP-mannose mannosyl hydrolase activity
HKNOCMOD_00823	4.56e-125	-	-	-	S	ko:K07095	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
HKNOCMOD_00824	4.74e-244	sun	2.1.1.176, 2.1.1.178	-	J	ko:K03500,ko:K11392	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HKNOCMOD_00825	5.9e-232	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HKNOCMOD_00826	1.46e-118	-	-	-	T	-	-	-	Prokaryotic dksA/traR C4-type zinc finger
HKNOCMOD_00827	5.67e-33	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L33
HKNOCMOD_00828	8.46e-50	-	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S18
HKNOCMOD_00829	3.84e-189	folE2	3.5.4.16	-	S	ko:K09007	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Type I GTP cyclohydrolase folE2
HKNOCMOD_00830	1.19e-177	-	-	-	S	-	-	-	Cytochrome C assembly protein
HKNOCMOD_00831	2.33e-239	hemA	1.2.1.70	-	H	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Glutamyl-tRNAGlu reductase, N-terminal domain
HKNOCMOD_00832	2.07e-235	-	2.5.1.61	-	H	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Porphobilinogen deaminase, dipyromethane cofactor binding domain
HKNOCMOD_00833	8.67e-85	-	-	-	S	-	-	-	Protein of unknown function, DUF488
HKNOCMOD_00834	0.0	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
HKNOCMOD_00835	1.12e-77	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	specificity
HKNOCMOD_00836	0.0	-	2.1.1.72	-	L	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
HKNOCMOD_00837	0.0	-	-	-	M	ko:K02847,ko:K13009,ko:K16705	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	-O-antigen
HKNOCMOD_00838	2.14e-108	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HKNOCMOD_00839	6.13e-174	-	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidine biosynthesis protein
HKNOCMOD_00840	3.01e-59	-	-	-	S	ko:K09131	-	ko00000	DUF167
HKNOCMOD_00841	1.16e-114	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HKNOCMOD_00842	4.01e-261	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HKNOCMOD_00843	1.56e-174	-	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HKNOCMOD_00844	1.41e-240	-	3.1.3.18	-	F	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD-hyrolase-like
HKNOCMOD_00845	0.0	-	-	-	M	-	-	-	Parallel beta-helix repeats
HKNOCMOD_00846	1.02e-228	-	2.5.1.32, 2.5.1.99	-	I	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Squalene/phytoene synthase
HKNOCMOD_00847	0.0	-	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Peptidase S24-like
HKNOCMOD_00848	0.0	-	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
HKNOCMOD_00849	6.29e-151	-	-	-	-	-	-	-	-
HKNOCMOD_00850	5.09e-168	pks6	-	-	Q	-	-	-	amino acid activation for nonribosomal peptide biosynthetic process
HKNOCMOD_00851	5.25e-175	-	-	-	S	-	-	-	Protein of unknown function (DUF3485)
HKNOCMOD_00852	1.19e-229	-	-	-	C	-	-	-	Transmembrane exosortase (Exosortase_EpsH)
HKNOCMOD_00853	4.58e-220	prs	2.7.6.1	-	EF	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HKNOCMOD_00854	1.24e-131	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HKNOCMOD_00856	1.48e-141	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Imidazoleglycerol-phosphate dehydratase
HKNOCMOD_00857	7.27e-145	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HKNOCMOD_00870	1.9e-36	-	-	-	L	-	-	-	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HKNOCMOD_00875	1.85e-20	-	-	-	-	-	-	-	-
HKNOCMOD_00876	2.28e-65	-	-	-	S	-	-	-	methyltransferase activity
HKNOCMOD_00882	4.96e-22	-	-	-	-	-	-	-	-
HKNOCMOD_00883	3.22e-15	-	-	-	-	-	-	-	-
HKNOCMOD_00885	3.4e-276	-	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
HKNOCMOD_00886	3.72e-238	-	-	-	O	-	-	-	Trypsin-like peptidase domain
HKNOCMOD_00887	0.0	-	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Transglycosylase
HKNOCMOD_00888	2.24e-281	-	-	-	S	ko:K09760	-	ko00000	RmuC family
HKNOCMOD_00889	9.06e-168	-	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD-hyrolase-like
HKNOCMOD_00890	1.25e-132	-	2.3.1.129	-	M	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	ko00000,ko00001,ko00002,ko01000,ko01005	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HKNOCMOD_00891	1.36e-185	-	-	-	S	-	-	-	RDD family
HKNOCMOD_00892	0.0	-	-	-	M	ko:K09808	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	MacB-like periplasmic core domain
HKNOCMOD_00893	0.0	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
HKNOCMOD_00895	0.0	-	-	-	H	ko:K02014	-	ko00000,ko02000	TonB dependent receptor
HKNOCMOD_00897	0.0	-	-	-	E	ko:K13893	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HKNOCMOD_00898	0.0	-	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Glycosyl hydrolases family 35
HKNOCMOD_00899	6.65e-160	-	-	-	M	ko:K16079	-	ko00000,ko02000	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HKNOCMOD_00900	3.4e-315	-	3.5.4.28, 3.5.4.31	-	F	ko:K12960	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Amidohydrolase family
HKNOCMOD_00901	0.0	-	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HKNOCMOD_00902	5.53e-96	-	-	-	S	-	-	-	Nucleotidyltransferase substrate binding protein like
HKNOCMOD_00903	4.46e-41	-	3.4.11.5	-	S	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	nucleotidyltransferase activity
HKNOCMOD_00904	4.48e-80	-	-	-	S	-	-	-	COG NOG09947 non supervised orthologous group
HKNOCMOD_00905	0.0	-	-	-	D	-	-	-	nuclear chromosome segregation
HKNOCMOD_00906	5.52e-35	-	-	-	-	-	-	-	-
HKNOCMOD_00907	2.13e-64	-	-	-	-	-	-	-	-
HKNOCMOD_00908	3.35e-28	-	-	-	-	-	-	-	-
HKNOCMOD_00910	6.8e-61	-	-	-	L	-	-	-	Membrane
HKNOCMOD_00911	3.37e-181	-	-	-	P	ko:K10716	-	ko00000,ko02000	domain protein
HKNOCMOD_00912	0.0	htpG	-	-	O	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	Hsp90 protein
HKNOCMOD_00913	0.0	-	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	transmembrane transport
HKNOCMOD_00914	5.22e-265	-	-	-	P	ko:K03449	-	ko00000,ko02000	Major Facilitator Superfamily
HKNOCMOD_00915	1.92e-239	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Aminoacyl tRNA synthetase class II, N-terminal domain
HKNOCMOD_00916	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	B3/4 domain
HKNOCMOD_00917	4.95e-246	-	-	-	S	-	-	-	Domain of unknown function (DUF4105)
HKNOCMOD_00918	1.66e-143	-	-	-	M	-	-	-	Peptidoglycan-binding domain 1 protein
HKNOCMOD_00919	0.0	-	4.1.99.1	-	E	ko:K01667	ko00380,map00380	ko00000,ko00001,ko01000	Beta-eliminating lyase
HKNOCMOD_00920	4.85e-66	-	-	-	K	ko:K03827	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HKNOCMOD_00921	4.08e-33	-	-	-	KLT	-	-	-	Tyrosine-protein kinase, subgroup, catalytic domain
HKNOCMOD_00922	1.89e-226	-	-	-	S	-	-	-	Protein conserved in bacteria
HKNOCMOD_00923	2.62e-209	-	-	-	S	-	-	-	ABC-type transport system involved in multi-copper enzyme maturation permease component
HKNOCMOD_00924	1.29e-156	-	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Methyladenine glycosylase
HKNOCMOD_00925	4.24e-179	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Pyrroline-5-carboxylate reductase dimerisation
HKNOCMOD_00928	6.75e-245	-	-	-	I	-	-	-	PFAM Prenyltransferase squalene oxidase
HKNOCMOD_00929	2.25e-119	-	-	-	-	-	-	-	-
HKNOCMOD_00930	0.0	-	-	-	D	-	-	-	nuclear chromosome segregation
HKNOCMOD_00931	0.0	-	5.4.99.2	-	I	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Methylmalonyl-CoA mutase
HKNOCMOD_00932	0.0	-	5.4.99.2	-	I	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Methylmalonyl-CoA mutase
HKNOCMOD_00934	4.01e-219	-	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	S-adenosylmethionine-dependent methyltransferase
HKNOCMOD_00935	2.29e-253	-	-	-	S	-	-	-	COG0790 FOG TPR repeat, SEL1 subfamily
HKNOCMOD_00936	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Phosphoglucose isomerase
HKNOCMOD_00937	0.0	-	2.7.9.1	-	G	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Pyruvate phosphate dikinase, PEP/pyruvate binding domain
HKNOCMOD_00938	1e-142	aat	2.3.2.6	-	O	ko:K00684	-	ko00000,ko01000	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
HKNOCMOD_00939	3.66e-253	-	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	endonuclease III
HKNOCMOD_00940	2.85e-214	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HKNOCMOD_00942	0.0	-	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen
HKNOCMOD_00944	5.27e-179	-	-	-	S	-	-	-	Integral membrane protein (intg_mem_TP0381)
HKNOCMOD_00945	3.2e-116	agmK	1.8.1.8	-	O	ko:K03671,ko:K03672	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko01000,ko03110	belongs to the thioredoxin family
HKNOCMOD_00946	7.21e-281	-	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
HKNOCMOD_00947	0.0	-	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
HKNOCMOD_00950	9.52e-108	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HKNOCMOD_00951	1.12e-169	-	-	-	S	-	-	-	Putative threonine/serine exporter
HKNOCMOD_00952	0.0	-	2.1.1.13	-	E	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	B12 binding domain
HKNOCMOD_00955	1.16e-142	-	-	-	Q	-	-	-	PA14
HKNOCMOD_00957	1.36e-96	-	-	-	-	-	-	-	-
HKNOCMOD_00958	0.0	mmyX	5.3.1.12	-	F	ko:K01812,ko:K07149,ko:K16139	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000,ko02000	Psort location Cytoplasmic, score
HKNOCMOD_00959	4.08e-112	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Cys-tRNA(Pro) hydrolase activity
HKNOCMOD_00960	2.8e-169	-	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Glutamine amidotransferase class-I
HKNOCMOD_00961	2.03e-116	-	-	-	T	ko:K07005	-	ko00000	pyridoxamine 5'-phosphate
HKNOCMOD_00962	9.92e-166	-	-	-	S	-	-	-	Integral membrane protein (intg_mem_TP0381)
HKNOCMOD_00963	2.38e-265	-	-	-	C	-	-	-	NADH:flavin oxidoreductase / NADH oxidase family
HKNOCMOD_00964	7.52e-144	-	4.1.3.27	-	EH	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Peptidase C26
HKNOCMOD_00965	2.74e-242	pabB	2.6.1.85, 4.1.3.27, 4.1.3.38	-	EH	ko:K01665,ko:K03342,ko:K13503,ko:K13950	ko00400,ko00790,ko01100,ko01110,ko01130,ko01230,map00400,map00790,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HKNOCMOD_00966	1.71e-144	-	4.1.3.38	-	E	ko:K02619	ko00790,map00790	ko00000,ko00001,ko01000	branched-chain-amino-acid transaminase activity
HKNOCMOD_00967	1.11e-312	-	5.1.3.8	-	G	ko:K01787	ko00520,map00520	ko00000,ko00001,ko01000	N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
HKNOCMOD_00968	4.61e-222	-	4.1.3.3	-	EM	ko:K01639	ko00520,map00520	ko00000,ko00001,ko01000	Dihydrodipicolinate synthetase family
HKNOCMOD_00969	0.0	-	-	-	-	-	-	-	-
HKNOCMOD_00970	1.47e-193	-	-	-	I	-	-	-	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
HKNOCMOD_00971	0.0	-	-	-	D	-	-	-	Tetratricopeptide repeat
HKNOCMOD_00972	1.86e-305	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HKNOCMOD_00973	0.0	-	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Adenylosuccinate lyase C-terminus
HKNOCMOD_00974	2.52e-102	MA20_05485	-	-	S	-	-	-	Putative bacterial sensory transduction regulator
HKNOCMOD_00975	3.92e-249	-	-	-	M	-	-	-	HlyD family secretion protein
HKNOCMOD_00976	0.0	-	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	Helix-hairpin-helix class 2 (Pol1 family) motifs
HKNOCMOD_00977	2.49e-123	-	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Phosphoribosyl transferase domain
HKNOCMOD_00979	1.93e-143	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
HKNOCMOD_00980	1.52e-245	-	-	-	S	-	-	-	Imelysin
HKNOCMOD_00981	0.0	-	-	-	C	-	-	-	Di-haem oxidoreductase, putative peroxidase
HKNOCMOD_00982	2.84e-263	-	-	-	J	-	-	-	Endoribonuclease L-PSP
HKNOCMOD_00983	1.53e-219	yclN	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	iron ion homeostasis
HKNOCMOD_00984	1.01e-227	fatC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	iron ion homeostasis
HKNOCMOD_00985	6.12e-180	yclP	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HKNOCMOD_00986	1.99e-208	fatB	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	iron ion transport
HKNOCMOD_00987	9.25e-177	ccs1	-	-	O	ko:K07399	-	ko00000	cytochrome c biogenesis protein
HKNOCMOD_00988	0.0	-	-	-	O	-	-	-	Cytochrome C assembly protein
HKNOCMOD_00989	4.54e-215	-	-	-	S	-	-	-	Acyltransferase family
HKNOCMOD_00990	9.99e-99	-	-	-	P	ko:K01138	-	ko00000,ko01000	COG3119 Arylsulfatase A and related enzymes
HKNOCMOD_00991	3.9e-40	-	-	-	P	ko:K01138	-	ko00000,ko01000	COG3119 Arylsulfatase A and related enzymes
HKNOCMOD_00992	0.0	-	-	-	G	-	-	-	beta-N-acetylhexosaminidase activity
HKNOCMOD_00994	2.22e-92	-	-	-	S	-	-	-	Protein of unknown function (DUF721)
HKNOCMOD_00995	4.64e-52	-	-	-	C	-	-	-	4Fe-4S single cluster domain of Ferredoxin I
HKNOCMOD_00996	0.0	-	-	GT2	M	ko:K03820	-	ko00000,ko01000	Carbon-nitrogen hydrolase
HKNOCMOD_00997	2.59e-175	-	-	-	S	-	-	-	Phosphodiester glycosidase
HKNOCMOD_00998	2.21e-228	-	2.7.7.13	-	JM	ko:K00966	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
HKNOCMOD_00999	0.0	fabZ	3.5.1.108, 4.2.1.59	-	IM	ko:K16363	ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis
HKNOCMOD_01001	5.39e-224	-	-	-	G	-	-	-	pfkB family carbohydrate kinase
HKNOCMOD_01002	1.66e-75	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HKNOCMOD_01003	1.59e-270	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Iron-containing alcohol dehydrogenase
HKNOCMOD_01008	1.46e-204	-	-	-	L	ko:K04763	-	ko00000,ko03036	Phage integrase, N-terminal SAM-like domain
HKNOCMOD_01009	1.26e-267	-	2.1.1.72	-	H	ko:K07318	-	ko00000,ko01000,ko02048	PFAM D12 class N6 adenine-specific DNA methyltransferase
HKNOCMOD_01011	2.08e-240	BT0173	-	-	S	-	-	-	Psort location Cytoplasmic, score
HKNOCMOD_01012	1.06e-169	BT0174	-	-	C	ko:K04488	-	ko00000	iron-sulfur transferase activity
HKNOCMOD_01013	6.98e-201	lpxG	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase
HKNOCMOD_01015	2.38e-99	cysJ	1.8.1.2	-	C	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	hydroxylamine reductase activity
HKNOCMOD_01017	1.43e-251	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HKNOCMOD_01018	1.33e-52	-	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HKNOCMOD_01019	5.52e-302	-	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
HKNOCMOD_01021	1.23e-310	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HKNOCMOD_01022	7.4e-85	-	-	-	S	ko:K06940	-	ko00000	Putative zinc- or iron-chelating domain
HKNOCMOD_01025	3.96e-189	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Bacitracin resistance protein BacA
HKNOCMOD_01026	1.75e-236	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HKNOCMOD_01027	0.0	gltX	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HKNOCMOD_01028	0.0	kefA	-	-	M	ko:K05802,ko:K22051	-	ko00000,ko02000	cellular water homeostasis
HKNOCMOD_01029	1.78e-97	queF	1.7.1.13	-	S	ko:K09457	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	QueF-like protein
HKNOCMOD_01030	1.02e-159	queC	6.3.4.20	-	F	ko:K06920	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Queuosine biosynthesis protein QueC
HKNOCMOD_01031	9.88e-145	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HKNOCMOD_01032	0.0	-	-	-	J	-	-	-	Beta-Casp domain
HKNOCMOD_01033	1.23e-62	-	-	-	S	-	-	-	Protein of unknown function (DUF1232)
HKNOCMOD_01034	1.75e-159	-	-	-	S	-	-	-	Protein of unknown function (DUF4230)
HKNOCMOD_01035	4.25e-306	-	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Isocitrate/isopropylmalate dehydrogenase
HKNOCMOD_01036	8.87e-268	-	-	-	S	-	-	-	Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units
HKNOCMOD_01037	8.31e-62	-	-	-	E	ko:K07032	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HKNOCMOD_01039	0.0	-	-	-	C	-	-	-	Cytochrome c
HKNOCMOD_01040	2.04e-294	-	-	-	P	-	-	-	ABC-type Zn2 transport system, periplasmic component surface adhesin
HKNOCMOD_01041	6.14e-155	-	-	-	C	-	-	-	Cytochrome c
HKNOCMOD_01043	1.65e-314	-	-	-	C	ko:K00185	-	ko00000	Polysulphide reductase, NrfD
HKNOCMOD_01048	5.04e-258	-	-	GT4	M	ko:K16703	-	ko00000,ko01000,ko01003	transferase activity, transferring glycosyl groups
HKNOCMOD_01049	3.51e-251	-	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HKNOCMOD_01050	3.87e-284	-	-	-	S	-	-	-	Phosphotransferase enzyme family
HKNOCMOD_01051	2.66e-252	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HKNOCMOD_01053	4.37e-135	-	-	-	T	-	-	-	histone H2A K63-linked ubiquitination
HKNOCMOD_01054	1.39e-130	-	2.1.1.63	-	L	ko:K00567	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HKNOCMOD_01055	8.47e-221	-	-	-	G	-	-	-	Glycosyl hydrolases family 16
HKNOCMOD_01056	2.02e-212	-	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HKNOCMOD_01057	0.0	-	-	-	T	ko:K06207	-	ko00000	Elongation factor G C-terminus
HKNOCMOD_01058	9.3e-236	-	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
HKNOCMOD_01059	7.68e-311	-	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-dependent decarboxylase, pyridoxal binding domain
HKNOCMOD_01060	6.62e-257	-	-	-	S	ko:K11744	-	ko00000	AI-2E family transporter
HKNOCMOD_01061	8.06e-156	gph	3.1.3.18, 3.6.1.1	-	S	ko:K01091,ko:K06019	ko00190,ko00630,ko01100,ko01110,ko01130,map00190,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	glycolate biosynthetic process
HKNOCMOD_01062	5.66e-295	-	-	-	E	-	-	-	Amino acid permease
HKNOCMOD_01063	2.02e-173	-	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Thiazole biosynthesis protein ThiG
HKNOCMOD_01065	1.79e-201	-	-	-	S	-	-	-	SigmaW regulon antibacterial
HKNOCMOD_01066	1.36e-242	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HKNOCMOD_01068	0.0	-	-	-	P	ko:K03455	-	ko00000	TrkA-N domain
HKNOCMOD_01069	0.0	-	-	-	P	-	-	-	Dimerisation domain of Zinc Transporter
HKNOCMOD_01070	5.84e-173	-	-	-	K	-	-	-	Transcriptional regulator
HKNOCMOD_01071	0.0	-	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HKNOCMOD_01072	9.46e-167	-	4.3.99.3	-	O	ko:K10026	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HKNOCMOD_01073	1.8e-179	-	2.7.13.3	-	Q	ko:K07777	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Transposase
HKNOCMOD_01074	0.0	-	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
HKNOCMOD_01075	7.67e-314	-	-	-	S	-	-	-	Protein of unknown function (DUF1015)
HKNOCMOD_01076	2.58e-252	-	-	-	E	-	-	-	Aminotransferase class-V
HKNOCMOD_01077	4.48e-233	-	-	-	S	-	-	-	Conserved hypothetical protein 698
HKNOCMOD_01078	4.27e-213	-	-	-	K	-	-	-	LysR substrate binding domain
HKNOCMOD_01081	5.28e-207	-	3.2.1.23	-	M	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
HKNOCMOD_01082	1.81e-59	-	3.2.1.23	-	M	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
HKNOCMOD_01083	0.0	-	-	-	I	-	-	-	PFAM Prenyltransferase squalene oxidase
HKNOCMOD_01084	2.07e-302	-	4.2.1.129, 5.4.99.17, 5.5.1.16	-	I	ko:K06045,ko:K17811	ko00909,ko01110,map00909,map01110	ko00000,ko00001,ko01000	PFAM Prenyltransferase squalene oxidase
HKNOCMOD_01085	4.66e-260	-	-	-	M	ko:K02022	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HKNOCMOD_01086	4.3e-158	-	-	-	S	-	-	-	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HKNOCMOD_01088	5.12e-71	-	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Thioredoxin-like domain
HKNOCMOD_01089	8.99e-313	-	-	-	-	-	-	-	-
HKNOCMOD_01090	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class II (D, K and N)
HKNOCMOD_01093	1.91e-164	-	-	-	L	ko:K03424	-	ko00000,ko01000	TatD related DNase
HKNOCMOD_01094	0.0	-	-	-	P	ko:K03455	-	ko00000	TrkA-N domain
HKNOCMOD_01095	4.72e-204	-	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
HKNOCMOD_01096	2.36e-270	-	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	Thermophilic metalloprotease (M29)
HKNOCMOD_01097	5.35e-139	-	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HKNOCMOD_01098	8.63e-188	-	5.2.1.8	-	O	ko:K03773	-	ko00000,ko01000,ko03110	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase
HKNOCMOD_01106	0.0	-	-	-	CO	-	-	-	Thioredoxin-like
HKNOCMOD_01110	5.35e-113	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HKNOCMOD_01111	0.0	-	-	-	S	ko:K07037	-	ko00000	7TM receptor with intracellular HD hydrolase
HKNOCMOD_01112	1.59e-242	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HKNOCMOD_01113	3.88e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
HKNOCMOD_01114	1.67e-115	-	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
HKNOCMOD_01115	6.98e-80	-	-	-	FG	ko:K02503	-	ko00000,ko04147	HIT domain
HKNOCMOD_01116	4.2e-242	-	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HKNOCMOD_01117	8.98e-128	aroK	2.7.1.71	-	E	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HKNOCMOD_01118	9.56e-51	-	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Ribosomal protein S16
HKNOCMOD_01120	4.58e-215	-	-	-	L	ko:K03733	-	ko00000,ko03036	Phage integrase, N-terminal SAM-like domain
HKNOCMOD_01121	1.08e-184	-	-	-	DTZ	-	-	-	EF-hand, calcium binding motif
HKNOCMOD_01122	5.64e-66	-	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit
HKNOCMOD_01123	5.68e-282	tgt	2.4.2.29	-	J	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HKNOCMOD_01124	1.22e-150	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Putative methyltransferase
HKNOCMOD_01125	4.32e-174	-	-	-	F	-	-	-	NUDIX domain
HKNOCMOD_01127	3.6e-145	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HKNOCMOD_01128	2.28e-44	-	-	-	J	-	-	-	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HKNOCMOD_01129	0.0	-	-	-	-	-	-	-	-
HKNOCMOD_01130	0.0	-	-	-	S	-	-	-	Sodium:neurotransmitter symporter family
HKNOCMOD_01131	1.47e-151	-	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	C-terminal domain of 1-Cys peroxiredoxin
HKNOCMOD_01132	2.84e-209	-	-	-	M	-	-	-	Mechanosensitive ion channel
HKNOCMOD_01133	4.62e-165	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Amino acid kinase family
HKNOCMOD_01134	1.47e-119	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HKNOCMOD_01135	9.17e-70	-	-	-	M	-	-	-	Polymer-forming cytoskeletal
HKNOCMOD_01136	2.41e-101	-	-	-	K	-	-	-	DNA-binding transcription factor activity
HKNOCMOD_01137	1.19e-228	-	-	-	J	-	-	-	Belongs to the universal ribosomal protein uS2 family
HKNOCMOD_01138	6.33e-211	-	-	-	L	-	-	-	Elongator protein 3, MiaB family, Radical SAM
HKNOCMOD_01139	1e-97	-	-	-	S	-	-	-	Maltose acetyltransferase
HKNOCMOD_01140	1.85e-150	-	-	-	H	-	-	-	HD superfamily hydrolase involved in NAD metabolism
HKNOCMOD_01141	0.0	-	-	-	S	ko:K07263	-	ko00000,ko01000,ko01002	Insulinase (Peptidase family M16)
HKNOCMOD_01144	7.65e-101	-	-	-	M	ko:K06077	-	ko00000	Glycine zipper 2TM domain
HKNOCMOD_01145	6.15e-234	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Converts alpha-aldose to the beta-anomer
HKNOCMOD_01146	2.89e-138	-	-	-	P	ko:K02039	-	ko00000	PhoU domain
HKNOCMOD_01147	5.24e-185	-	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HKNOCMOD_01148	1.51e-221	-	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	PBP superfamily domain
HKNOCMOD_01149	0.0	pstC	-	-	P	ko:K02037,ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKNOCMOD_01150	0.0	-	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKNOCMOD_01151	4.85e-185	-	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HKNOCMOD_01152	6.05e-148	phoU	-	-	P	ko:K02039	-	ko00000	negative regulation of phosphate transmembrane transport
HKNOCMOD_01153	6.21e-213	-	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
HKNOCMOD_01154	2.32e-167	-	1.8.4.10, 1.8.4.8	-	EH	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Phosphoadenosine phosphosulfate reductase family
HKNOCMOD_01155	9.99e-216	-	2.7.7.4	-	EH	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoadenosine phosphosulfate reductase family
HKNOCMOD_01156	0.0	-	2.7.1.25, 2.7.7.4	-	P	ko:K00955	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily
HKNOCMOD_01157	4.35e-233	-	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	NMT1/THI5 like
HKNOCMOD_01158	2.77e-178	-	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HKNOCMOD_01159	3.23e-174	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKNOCMOD_01160	0.0	-	1.8.1.2	-	P	ko:K00381	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Nitrite and sulphite reductase 4Fe-4S domain
HKNOCMOD_01162	1.01e-274	-	-	-	J	-	-	-	PFAM Endoribonuclease L-PSP
HKNOCMOD_01163	0.0	-	-	-	C	-	-	-	cytochrome C peroxidase
HKNOCMOD_01164	0.0	-	-	-	U	-	-	-	Involved in the tonB-independent uptake of proteins
HKNOCMOD_01165	1.99e-19	-	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	COG0010 Arginase agmatinase formimionoglutamate hydrolase arginase family
HKNOCMOD_01166	2.92e-296	-	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase family U32
HKNOCMOD_01167	1.87e-147	-	-	-	C	-	-	-	lactate oxidation
HKNOCMOD_01168	0.0	-	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	DNA Topoisomerase IV
HKNOCMOD_01169	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HKNOCMOD_01172	6.21e-39	-	-	-	-	-	-	-	-
HKNOCMOD_01173	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HKNOCMOD_01175	7.42e-230	-	-	-	CO	-	-	-	Thioredoxin-like
HKNOCMOD_01176	0.0	-	-	-	P	-	-	-	Domain of unknown function (DUF4976)
HKNOCMOD_01177	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycoside hydrolase, family 20, catalytic core
HKNOCMOD_01178	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class I (C) catalytic domain
HKNOCMOD_01179	1.22e-72	-	-	-	G	-	-	-	Cupin 2, conserved barrel domain protein
HKNOCMOD_01180	1.97e-202	ybfH	-	-	EG	-	-	-	spore germination
HKNOCMOD_01181	0.0	-	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
HKNOCMOD_01182	6.01e-120	-	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HKNOCMOD_01183	8.73e-187	-	-	-	O	ko:K04083	-	ko00000,ko03110	Hsp33 protein
HKNOCMOD_01186	1.32e-94	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
HKNOCMOD_01188	6.01e-132	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
HKNOCMOD_01195	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKNOCMOD_01197	3.69e-64	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HKNOCMOD_01198	9.92e-110	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HKNOCMOD_01199	4.97e-156	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HKNOCMOD_01200	2.58e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HKNOCMOD_01201	6.29e-135	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	In Spt5p, this domain may confer affinity for Spt4p. It possesses a RNP-like fold.
HKNOCMOD_01202	3.61e-46	-	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	SecE/Sec61-gamma subunits of protein translocation complex
HKNOCMOD_01204	9.94e-287	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HKNOCMOD_01206	2.49e-256	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HKNOCMOD_01207	0.0	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HKNOCMOD_01208	2.5e-153	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HKNOCMOD_01209	9.77e-281	tig	-	-	O	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HKNOCMOD_01210	0.0	-	-	-	M	ko:K07277	-	ko00000,ko02000,ko03029	Surface antigen
HKNOCMOD_01211	2.68e-152	-	1.14.11.27	-	P	ko:K10277	-	ko00000,ko01000,ko03036	peptidyl-arginine hydroxylation
HKNOCMOD_01212	2.6e-231	-	1.5.1.20	-	E	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Methylenetetrahydrofolate reductase
HKNOCMOD_01213	3.95e-168	-	-	-	CO	-	-	-	Protein conserved in bacteria
HKNOCMOD_01214	3.44e-146	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKNOCMOD_01215	0.0	-	-	-	P	ko:K07239	-	ko00000	AcrB/AcrD/AcrF family
HKNOCMOD_01216	7.96e-297	czcB	-	-	M	ko:K15727	-	ko00000,ko02000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HKNOCMOD_01217	5.02e-294	-	-	-	MU	ko:K15725	-	ko00000,ko02000	efflux transmembrane transporter activity
HKNOCMOD_01219	3.17e-206	-	-	-	G	ko:K06867,ko:K07001	-	ko00000	response to abiotic stimulus
HKNOCMOD_01220	0.0	-	-	-	E	-	-	-	PFAM major facilitator superfamily MFS_1
HKNOCMOD_01223	1.36e-214	-	-	-	KQ	-	-	-	Hypothetical methyltransferase
HKNOCMOD_01224	5.14e-289	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HKNOCMOD_01225	0.0	ahcY	3.3.1.1	-	H	ko:K01251	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
HKNOCMOD_01226	3.5e-249	rgpB	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HKNOCMOD_01227	1.21e-244	-	-	-	-	-	-	-	-
HKNOCMOD_01228	0.0	-	-	-	H	-	-	-	Flavin containing amine oxidoreductase
HKNOCMOD_01229	8.66e-227	-	-	-	-	-	-	-	-
HKNOCMOD_01230	1.42e-117	-	-	-	P	-	-	-	Domain of unknown function (DUF4976)
HKNOCMOD_01231	0.0	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
HKNOCMOD_01232	0.0	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	amino acid
HKNOCMOD_01233	8.6e-222	-	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Glutaminase
HKNOCMOD_01234	2.43e-95	-	-	-	K	-	-	-	-acetyltransferase
HKNOCMOD_01235	1.17e-307	-	-	-	E	ko:K03310	-	ko00000	Sodium:alanine symporter family
HKNOCMOD_01237	3.95e-252	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HKNOCMOD_01238	1.12e-211	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HKNOCMOD_01241	1.16e-243	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HKNOCMOD_01243	3.22e-15	-	-	-	-	-	-	-	-
HKNOCMOD_01244	0.0	-	-	-	E	-	-	-	Sodium:solute symporter family
HKNOCMOD_01245	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HKNOCMOD_01246	1.14e-178	kdsB	2.7.7.38	-	M	ko:K00979	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
HKNOCMOD_01247	1.95e-198	-	-	-	-	-	-	-	-
HKNOCMOD_01249	1.08e-244	ppiD	5.2.1.8	-	O	ko:K03769,ko:K03770,ko:K03771,ko:K07533	-	ko00000,ko01000,ko03110	peptidyl-prolyl cis-trans isomerase activity
HKNOCMOD_01250	2.61e-260	-	-	-	NU	ko:K02669	-	ko00000,ko02035,ko02044	Type II/IV secretion system protein
HKNOCMOD_01251	5.1e-265	-	-	-	NU	ko:K02669	-	ko00000,ko02035,ko02044	Type II/IV secretion system protein
HKNOCMOD_01254	2.69e-38	-	-	-	T	-	-	-	ribosome binding
HKNOCMOD_01255	7.39e-229	-	-	-	Q	ko:K02067	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	MlaD protein
HKNOCMOD_01256	6.12e-190	-	-	-	Q	ko:K02065	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
HKNOCMOD_01257	7.86e-174	-	-	-	Q	ko:K02066	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Permease MlaE
HKNOCMOD_01258	8.74e-314	-	-	-	H	-	-	-	NAD synthase
HKNOCMOD_01259	0.0	-	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter transmembrane region
HKNOCMOD_01260	0.0	-	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter transmembrane region
HKNOCMOD_01261	0.0	-	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III
HKNOCMOD_01262	3.9e-144	-	-	-	M	-	-	-	NLP P60 protein
HKNOCMOD_01263	6.55e-292	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HKNOCMOD_01264	7.67e-300	-	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Tubulin/FtsZ family, GTPase domain
HKNOCMOD_01269	6.27e-229	-	-	-	S	ko:K01128	-	ko00000,ko01000	acid phosphatase activity
HKNOCMOD_01270	8.85e-309	-	1.5.1.7	-	E	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Saccharopine dehydrogenase C-terminal domain
HKNOCMOD_01271	1.37e-211	-	-	-	O	-	-	-	Thioredoxin-like domain
HKNOCMOD_01272	0.0	-	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HKNOCMOD_01273	5.13e-214	-	-	-	EP	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKNOCMOD_01274	3.1e-211	-	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	N-terminal TM domain of oligopeptide transport permease C
HKNOCMOD_01275	8.28e-84	-	-	-	S	ko:K09922	-	ko00000	Putative member of DMT superfamily (DUF486)
HKNOCMOD_01276	6.2e-271	-	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	tRNA synthetases class I (W and Y)
HKNOCMOD_01277	1.11e-235	-	-	-	S	ko:K14347	-	ko00000,ko02000,ko04147	SBF-like CPA transporter family (DUF4137)
HKNOCMOD_01280	0.0	-	-	-	S	-	-	-	Large extracellular alpha-helical protein
HKNOCMOD_01281	0.0	-	-	-	M	-	-	-	Aerotolerance regulator N-terminal
HKNOCMOD_01282	1.23e-226	-	-	-	S	-	-	-	Peptidase family M28
HKNOCMOD_01283	4.83e-198	-	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	ParB-like nuclease domain
HKNOCMOD_01286	0.0	-	4.2.1.9	-	EG	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Dehydratase family
HKNOCMOD_01287	1.39e-167	-	-	-	T	ko:K07657	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
HKNOCMOD_01288	1.57e-288	-	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
HKNOCMOD_01292	2.09e-10	-	-	-	S	-	-	-	Mitochondrial domain of unknown function (DUF1713)
HKNOCMOD_01293	2.25e-206	hisG	2.4.2.17	-	E	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	ATP phosphoribosyltransferase
HKNOCMOD_01294	6.85e-313	-	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	Aminopeptidase P, N-terminal domain
HKNOCMOD_01295	3.29e-154	-	-	-	S	-	-	-	Protein of unknown function (DUF3313)
HKNOCMOD_01296	3.57e-261	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HKNOCMOD_01297	3.28e-256	-	-	-	G	-	-	-	M42 glutamyl aminopeptidase
HKNOCMOD_01298	2.69e-167	-	-	-	-	-	-	-	-
HKNOCMOD_01299	0.0	-	-	-	NU	-	-	-	Type IV pilus assembly protein PilM;
HKNOCMOD_01300	3.03e-208	-	-	-	-	-	-	-	-
HKNOCMOD_01301	1.31e-244	-	-	-	-	-	-	-	-
HKNOCMOD_01302	0.0	-	-	-	NU	ko:K02453	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02044	Bacterial type II and III secretion system protein
HKNOCMOD_01303	0.0	-	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HKNOCMOD_01304	0.0	-	-	-	P	-	-	-	E1-E2 ATPase
HKNOCMOD_01305	5.74e-241	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HKNOCMOD_01306	1.1e-131	tadA	3.5.4.33	-	FJ	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HKNOCMOD_01307	4.47e-228	lipA	2.8.1.8	-	H	ko:K03644	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HKNOCMOD_01308	0.0	-	1.11.1.5	-	P	ko:K00428	-	ko00000,ko01000	Di-haem cytochrome c peroxidase
HKNOCMOD_01309	2.48e-40	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	iron ion homeostasis
HKNOCMOD_01310	4.02e-48	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	iron ion homeostasis
HKNOCMOD_01311	0.0	-	-	-	P	ko:K04759	-	ko00000,ko02000	Ferrous iron transport protein B C terminus
HKNOCMOD_01314	2.83e-303	-	-	-	M	ko:K07267	-	ko00000,ko02000	wide pore channel activity
HKNOCMOD_01317	0.0	-	-	-	P	-	-	-	E1-E2 ATPase
HKNOCMOD_01318	9.94e-90	-	-	-	K	-	-	-	Helix-turn-helix diphteria tox regulatory element
HKNOCMOD_01319	3.08e-204	-	3.1.1.53	-	L	ko:K03547,ko:K05970	-	ko00000,ko01000,ko03400	3'-5' exonuclease activity
HKNOCMOD_01320	7.03e-134	-	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	SpoU rRNA Methylase family
HKNOCMOD_01321	0.0	-	1.4.3.16	-	H	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Fumarate reductase flavoprotein C-term
HKNOCMOD_01322	1.81e-253	-	-	-	S	-	-	-	Glycoside-hydrolase family GH114
HKNOCMOD_01323	1.06e-301	-	-	-	M	-	-	-	Glycosyl transferases group 1
HKNOCMOD_01325	0.0	-	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	RecQ zinc-binding
HKNOCMOD_01327	3.24e-173	-	-	-	C	ko:K00184	-	ko00000	4Fe-4S dicluster domain
HKNOCMOD_01329	0.0	-	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	RecG wedge domain
HKNOCMOD_01330	1.15e-165	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	PFAM N-acetylmuramoyl-L-alanine amidase family 2
HKNOCMOD_01331	0.0	pckG	4.1.1.32	-	C	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle
HKNOCMOD_01333	9.05e-85	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	4'-phosphopantetheinyl transferase superfamily
HKNOCMOD_01334	5.64e-173	pdxJ	2.6.99.2	-	H	ko:K03474	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HKNOCMOD_01335	0.0	-	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	AICARFT/IMPCHase bienzyme
HKNOCMOD_01336	1.06e-94	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L9, N-terminal domain
HKNOCMOD_01337	7.38e-227	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HKNOCMOD_01338	3.2e-209	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
HKNOCMOD_01339	2.84e-18	-	-	-	S	-	-	-	Lipocalin-like
HKNOCMOD_01341	8.77e-239	cbiM	-	-	P	ko:K02007,ko:K02009,ko:K16915	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt ion transport
HKNOCMOD_01342	2.42e-195	cbiQ	-	-	P	ko:K02007,ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transmembrane transporter activity
HKNOCMOD_01343	4.82e-179	cbiO	-	-	P	ko:K02006,ko:K02008,ko:K16784,ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPase activity
HKNOCMOD_01344	0.0	-	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	HELICc2
HKNOCMOD_01346	3.48e-210	ispE	2.7.1.148	-	I	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	GHMP kinases N terminal domain
HKNOCMOD_01347	0.0	-	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	TopoisomeraseII
HKNOCMOD_01348	6.14e-173	-	2.5.1.31	-	I	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HKNOCMOD_01349	2.41e-259	-	2.7.7.13	-	M	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
HKNOCMOD_01350	3.03e-96	-	-	-	L	ko:K07447	-	ko00000,ko01000	Likely ribonuclease with RNase H fold.
HKNOCMOD_01351	1.34e-235	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
HKNOCMOD_01352	1.45e-55	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L28 family
HKNOCMOD_01353	1.04e-49	-	-	-	-	-	-	-	-
HKNOCMOD_01354	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Alpha galactosidase A
HKNOCMOD_01355	2.5e-219	-	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HKNOCMOD_01356	0.0	-	-	-	E	-	-	-	Aminotransferase class I and II
HKNOCMOD_01357	4.6e-305	-	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HKNOCMOD_01358	1.04e-78	divIC	-	-	D	ko:K05589,ko:K13052	-	ko00000,ko03036	cell cycle
HKNOCMOD_01359	0.0	-	-	-	P	-	-	-	Sulfatase
HKNOCMOD_01361	2.22e-263	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
HKNOCMOD_01363	2.65e-150	-	-	-	K	-	-	-	Transcriptional regulator
HKNOCMOD_01364	2.92e-189	-	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HKNOCMOD_01365	1.35e-236	-	1.1.1.86	-	E	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HKNOCMOD_01366	1.03e-121	-	-	-	M	ko:K03098	-	ko00000,ko04147	Lipocalin-like domain
HKNOCMOD_01367	7.83e-206	-	-	-	S	ko:K07071	-	ko00000	Domain of unknown function (DUF1731)
HKNOCMOD_01368	5.75e-202	-	-	-	O	-	-	-	stress-induced mitochondrial fusion
HKNOCMOD_01370	9.45e-239	-	-	-	E	-	-	-	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HKNOCMOD_01372	1.73e-295	-	-	-	S	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
HKNOCMOD_01374	3.9e-306	-	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HKNOCMOD_01375	4.86e-110	msrB	1.8.4.11, 1.8.4.12	-	O	ko:K07305,ko:K12267	-	ko00000,ko01000	peptide-methionine (R)-S-oxide reductase activity
HKNOCMOD_01376	4.16e-259	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HKNOCMOD_01377	1.92e-300	nupG	-	-	G	ko:K03289,ko:K03301,ko:K08218,ko:K11537	ko01501,map01501	ko00000,ko00001,ko00002,ko02000	Major facilitator Superfamily
HKNOCMOD_01380	1.2e-243	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HKNOCMOD_01381	3.43e-242	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HKNOCMOD_01382	0.0	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HKNOCMOD_01383	5.59e-227	-	-	-	M	ko:K01993	-	ko00000	HlyD family secretion protein
HKNOCMOD_01384	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HKNOCMOD_01385	3.85e-194	-	2.7.8.8	-	I	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	CDP-alcohol phosphatidyltransferase
HKNOCMOD_01386	4.03e-120	-	-	-	-	-	-	-	-
HKNOCMOD_01387	5.27e-197	-	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HKNOCMOD_01388	0.0	-	-	-	M	-	-	-	Bacterial membrane protein, YfhO
HKNOCMOD_01389	0.0	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	GcpE protein
HKNOCMOD_01390	9.4e-148	-	-	-	IQ	-	-	-	RmlD substrate binding domain
HKNOCMOD_01391	3.08e-286	-	-	-	S	-	-	-	Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units
HKNOCMOD_01392	0.0	-	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	thiolester hydrolase activity
HKNOCMOD_01393	7.26e-285	-	-	-	IQ	-	-	-	Beta-ketoacyl synthase, C-terminal domain
HKNOCMOD_01394	1.1e-259	-	2.3.1.47	-	H	ko:K00652	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
HKNOCMOD_01398	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HKNOCMOD_01399	1.42e-308	-	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Histidyl-tRNA synthetase
HKNOCMOD_01400	2.05e-175	hypB	-	-	KO	ko:K04652	-	ko00000,ko03110	CobW/HypB/UreG, nucleotide-binding domain
HKNOCMOD_01401	0.0	-	-	-	O	ko:K04656	-	ko00000	HypF finger
HKNOCMOD_01402	5.54e-50	-	-	-	O	ko:K04653	-	ko00000	HupF/HypC family
HKNOCMOD_01403	7.17e-258	-	-	-	O	ko:K04654	-	ko00000	Hydrogenase formation hypA family
HKNOCMOD_01404	6.21e-242	-	-	-	O	ko:K04655	-	ko00000	AIR synthase related protein, N-terminal domain
HKNOCMOD_01405	1.56e-280	-	-	-	S	-	-	-	COG0790 FOG TPR repeat, SEL1 subfamily
HKNOCMOD_01406	0.0	-	-	-	M	-	-	-	Glycosyl transferase 4-like domain
HKNOCMOD_01407	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	MreB/Mbl protein
HKNOCMOD_01408	2.2e-61	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HKNOCMOD_01409	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HKNOCMOD_01410	1.52e-98	-	-	-	S	-	-	-	peptidase
HKNOCMOD_01411	0.0	-	-	-	P	ko:K03306	-	ko00000	phosphate transporter
HKNOCMOD_01415	5.42e-296	-	-	-	-	-	-	-	-
HKNOCMOD_01416	0.0	-	-	-	D	-	-	-	Chain length determinant protein
HKNOCMOD_01417	7.55e-142	-	-	-	M	-	-	-	Polysaccharide biosynthesis/export protein
HKNOCMOD_01419	1.09e-148	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HKNOCMOD_01420	1.67e-249	-	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
HKNOCMOD_01421	6.72e-285	pgk	2.7.2.3	-	G	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Phosphoglycerate kinase
HKNOCMOD_01422	5.72e-243	-	-	-	-	-	-	-	-
HKNOCMOD_01423	0.0	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	myo-inosose-2 dehydratase activity
HKNOCMOD_01425	0.0	-	-	-	S	ko:K07126	-	ko00000	beta-lactamase activity
HKNOCMOD_01426	0.0	-	-	-	L	-	-	-	TRCF
HKNOCMOD_01427	7.64e-291	-	-	-	-	-	-	-	-
HKNOCMOD_01428	0.0	-	-	-	G	-	-	-	Major Facilitator Superfamily
HKNOCMOD_01429	2.11e-254	-	-	-	S	-	-	-	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
HKNOCMOD_01431	5.56e-214	-	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	PHP domain
HKNOCMOD_01432	1.4e-259	-	2.3.1.8	-	C	ko:K00625	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Phosphate acetyl/butaryl transferase
HKNOCMOD_01433	1.65e-241	tilS	6.3.4.19	-	D	ko:K04075	-	ko00000,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HKNOCMOD_01434	2.59e-75	-	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
HKNOCMOD_01438	5.41e-100	-	-	-	MP	-	-	-	regulation of cell-substrate adhesion
HKNOCMOD_01441	0.0	-	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	UDP binding domain
HKNOCMOD_01442	1.83e-231	-	1.1.1.37	-	C	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible oxidation of malate to oxaloacetate
HKNOCMOD_01443	0.0	-	-	-	G	-	-	-	Glycogen debranching enzyme
HKNOCMOD_01444	0.0	-	-	-	M	-	-	-	NPCBM/NEW2 domain
HKNOCMOD_01445	0.0	-	-	-	M	ko:K04744	-	ko00000,ko02000	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
HKNOCMOD_01446	1.15e-152	-	1.5.1.34	-	C	ko:K10679	ko00633,ko01120,map00633,map01120	ko00000,ko00001,ko01000	Nitroreductase family
HKNOCMOD_01447	1.75e-184	-	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	RNA pseudouridylate synthase
HKNOCMOD_01448	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
HKNOCMOD_01451	8.47e-122	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	adenylate kinase activity
HKNOCMOD_01452	5.08e-166	-	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HKNOCMOD_01453	0.0	-	-	-	ET	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
HKNOCMOD_01454	4.55e-170	-	-	-	S	-	-	-	Terminase
HKNOCMOD_01462	1.97e-64	-	2.1.1.72	-	L	ko:K06223	ko03430,map03430	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	PFAM D12 class N6 adenine-specific DNA methyltransferase
HKNOCMOD_01467	1.14e-07	-	-	-	T	-	-	-	pathogenesis
HKNOCMOD_01468	0.0	-	2.3.1.40, 6.2.1.20	-	IQ	ko:K05939	ko00071,ko00564,map00071,map00564	ko00000,ko00001,ko01000	AMP-binding enzyme
HKNOCMOD_01469	0.0	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HKNOCMOD_01470	6.39e-71	-	-	-	-	-	-	-	-
HKNOCMOD_01474	2.43e-209	-	-	-	S	ko:K03453	-	ko00000	Bile acid
HKNOCMOD_01475	5.4e-292	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HKNOCMOD_01476	2.55e-268	sucC	6.2.1.5	-	C	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HKNOCMOD_01477	3.89e-209	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HKNOCMOD_01478	4.71e-175	-	-	-	-	-	-	-	-
HKNOCMOD_01480	0.0	-	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	RQC
HKNOCMOD_01486	3.4e-231	-	-	-	S	-	-	-	mannose-ethanolamine phosphotransferase activity
HKNOCMOD_01488	2.91e-114	-	-	-	S	ko:K03748	-	ko00000	DUF218 domain
HKNOCMOD_01490	3.15e-103	-	-	-	J	-	-	-	YjgF/chorismate_mutase-like, putative endoribonuclease
HKNOCMOD_01491	0.0	-	-	-	-	-	-	-	-
HKNOCMOD_01492	3.01e-113	-	1.16.3.2	-	P	ko:K02217	-	ko00000,ko01000	Ferritin-like domain
HKNOCMOD_01494	4.98e-92	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HKNOCMOD_01495	1.25e-307	-	4.2.1.20	-	E	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HKNOCMOD_01496	1.06e-235	-	2.7.1.221	-	S	ko:K07102	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Phosphotransferase enzyme family
HKNOCMOD_01497	0.0	-	-	-	T	-	-	-	Chase2 domain
HKNOCMOD_01498	1.92e-106	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Low molecular weight phosphatase family
HKNOCMOD_01499	2.06e-108	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
HKNOCMOD_01500	0.0	-	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome bd terminal oxidase subunit I
HKNOCMOD_01501	2.73e-241	-	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome bd terminal oxidase subunit II
HKNOCMOD_01502	0.0	-	1.2.4.2	-	C	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	2-oxoglutarate dehydrogenase C-terminal
HKNOCMOD_01503	4.01e-227	-	2.3.1.61	-	C	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	2-oxoacid dehydrogenases acyltransferase (catalytic domain)
HKNOCMOD_01504	2.39e-08	-	2.7.1.72	-	V	ko:K04343	-	br01600,ko00000,ko00002,ko01000,ko01504	Aminoglycoside/hydroxyurea antibiotic resistance kinase
HKNOCMOD_01505	9.4e-210	MA20_42350	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	Glycosyl transferase, family 2
HKNOCMOD_01506	1.29e-282	-	1.8.1.2	-	P	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HKNOCMOD_01507	1.11e-237	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HKNOCMOD_01508	3.4e-243	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HKNOCMOD_01512	0.0	-	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	transmembrane transport
HKNOCMOD_01513	9.92e-317	-	3.2.1.18	GH33	G	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	ko00000,ko00001,ko01000,ko02042	BNR/Asp-box repeat
HKNOCMOD_01514	4.7e-234	-	-	-	K	-	-	-	Periplasmic binding protein-like domain
HKNOCMOD_01515	0.0	-	3.2.1.18	GH33	G	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	ko00000,ko00001,ko01000,ko02042	exo-alpha-(2->6)-sialidase activity
HKNOCMOD_01517	2.28e-79	-	-	-	P	ko:K11741	-	ko00000,ko02000	Small Multidrug Resistance protein
HKNOCMOD_01518	0.0	-	6.3.5.1	-	H	ko:K01950	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	NAD synthase
HKNOCMOD_01519	4.16e-181	-	-	-	Q	-	-	-	methyltransferase activity
HKNOCMOD_01521	4.69e-139	-	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	Serine/threonine phosphatases, family 2C, catalytic domain
HKNOCMOD_01522	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase large chain, oligomerisation domain
HKNOCMOD_01523	2.94e-195	-	-	-	-	-	-	-	-
HKNOCMOD_01524	2.84e-118	-	3.2.2.28	-	L	ko:K03649	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	G/U mismatch-specific uracil-DNA glycosylase activity
HKNOCMOD_01525	2.56e-223	-	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III, delta subunit
HKNOCMOD_01526	6.8e-115	hisI	3.5.4.19	-	E	ko:K01496	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Phosphoribosyl-AMP cyclohydrolase
HKNOCMOD_01527	2.5e-165	-	-	-	S	ko:K05807	-	ko00000,ko02000	Outer membrane lipoprotein
HKNOCMOD_01528	6.93e-112	-	-	-	S	-	-	-	Lipopolysaccharide-assembly
HKNOCMOD_01529	4.14e-164	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Tetrapyrrole (Corrin/Porphyrin) Methylases
HKNOCMOD_01530	4.4e-180	-	-	-	S	-	-	-	Endonuclease/Exonuclease/phosphatase family
HKNOCMOD_01531	1.5e-17	-	-	-	-	-	-	-	-
HKNOCMOD_01532	7.51e-06	ANKRD17	-	-	T	ko:K16726	-	ko00000,ko03036	domain-containing protein
HKNOCMOD_01535	1.85e-59	-	-	-	K	-	-	-	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen
HKNOCMOD_01537	5.39e-13	-	-	-	S	-	-	-	SPFH domain-Band 7 family
HKNOCMOD_01541	2.06e-119	-	-	-	M	-	-	-	Glycosyl transferase, family 2
HKNOCMOD_01542	9.37e-27	-	-	-	H	-	-	-	PFAM glycosyl transferase family 8
HKNOCMOD_01543	6.25e-190	-	-	-	H	-	-	-	PFAM glycosyl transferase family 8
HKNOCMOD_01545	3.45e-200	-	-	-	G	-	-	-	Class II Aldolase and Adducin N-terminal domain
HKNOCMOD_01546	0.0	-	2.7.1.51	-	G	ko:K00879	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
HKNOCMOD_01547	0.0	fucI	5.3.1.25, 5.3.1.3	-	G	ko:K01818	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Converts the aldose L-fucose into the corresponding ketose L-fuculose
HKNOCMOD_01548	0.0	-	-	-	G	-	-	-	Major Facilitator Superfamily
HKNOCMOD_01549	3.87e-113	-	-	-	-	-	-	-	-
HKNOCMOD_01550	0.0	-	3.2.1.18	GH33	G	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	ko00000,ko00001,ko01000,ko02042	N-terminal domain of BNR-repeat neuraminidase
HKNOCMOD_01551	1.11e-132	-	-	-	K	ko:K03088	-	ko00000,ko03021	ECF sigma factor
HKNOCMOD_01552	5.8e-20	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HKNOCMOD_01553	7.29e-60	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	negative regulation of transcription, DNA-templated
HKNOCMOD_01554	0.0	copA	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
HKNOCMOD_01555	0.0	-	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	ThiC-associated domain
HKNOCMOD_01556	1.48e-218	ytpP	2.7.1.180, 5.3.4.1	-	CO	ko:K01829,ko:K03671,ko:K03734,ko:K06196	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko01000,ko02000,ko03110	cell redox homeostasis
HKNOCMOD_01557	1.07e-138	-	-	-	K	-	-	-	ECF sigma factor
HKNOCMOD_01559	6.79e-222	-	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
HKNOCMOD_01560	1.39e-230	-	-	-	O	-	-	-	Parallel beta-helix repeats
HKNOCMOD_01561	0.0	-	3.1.5.1	-	F	ko:K01129	ko00230,map00230	ko00000,ko00001,ko01000	Phosphohydrolase-associated domain
HKNOCMOD_01562	5.16e-282	-	-	-	Q	-	-	-	Multicopper oxidase
HKNOCMOD_01563	8.5e-212	-	-	-	EG	-	-	-	EamA-like transporter family
HKNOCMOD_01565	2.2e-274	-	5.1.1.1	-	M	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HKNOCMOD_01566	6.48e-244	-	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
HKNOCMOD_01567	9.42e-232	-	-	-	EP	ko:K02031	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
HKNOCMOD_01568	0.0	-	-	-	E	ko:K13893	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HKNOCMOD_01569	0.0	-	-	-	P	ko:K13895	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKNOCMOD_01570	0.0	-	-	-	EP	ko:K13894	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKNOCMOD_01571	2.28e-180	-	-	-	T	-	-	-	Calcineurin-like phosphoesterase superfamily domain
HKNOCMOD_01572	5.52e-207	-	-	-	S	-	-	-	Tetratricopeptide repeat
HKNOCMOD_01573	9.98e-223	-	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Ketopantoate reductase PanE/ApbA C terminal
HKNOCMOD_01574	0.0	fhs	6.3.4.3	-	H	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Formate--tetrahydrofolate ligase
HKNOCMOD_01575	1.36e-143	-	-	-	S	ko:K09974	-	ko00000	Domain of unknown function (DUF1287)
HKNOCMOD_01576	4.11e-314	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain
HKNOCMOD_01578	7.68e-33	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HKNOCMOD_01580	1.75e-254	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Semialdehyde dehydrogenase, NAD binding domain
HKNOCMOD_01581	2.26e-306	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HKNOCMOD_01582	1.01e-110	-	-	-	S	-	-	-	Putative zinc- or iron-chelating domain
HKNOCMOD_01583	7.7e-31	-	-	-	S	ko:K07126	-	ko00000	Sel1-like repeats.
HKNOCMOD_01585	0.0	-	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	ATPases associated with a variety of cellular activities
HKNOCMOD_01586	4.17e-149	-	-	-	M	-	-	-	Polymer-forming cytoskeletal
HKNOCMOD_01587	3.28e-126	-	-	-	M	-	-	-	Polymer-forming cytoskeletal
HKNOCMOD_01588	2.87e-248	-	-	-	-	-	-	-	-
HKNOCMOD_01590	7.19e-234	-	-	-	E	-	-	-	PFAM lipolytic protein G-D-S-L family
HKNOCMOD_01594	1.69e-129	-	-	-	U	ko:K05595	-	ko00000,ko02000	MarC family integral membrane protein
HKNOCMOD_01595	2.42e-177	-	4.2.99.20	-	I	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Alpha/beta hydrolase family
HKNOCMOD_01596	1.46e-75	-	-	-	S	ko:K09954	-	ko00000	Putative quorum-sensing-regulated virulence factor
HKNOCMOD_01598	1.24e-51	-	-	-	-	-	-	-	-
HKNOCMOD_01599	4.19e-133	-	-	-	S	-	-	-	Protein of unknown function (DUF2589)
HKNOCMOD_01600	5.18e-182	-	-	-	-	-	-	-	-
HKNOCMOD_01601	2.59e-174	-	-	-	S	-	-	-	Protein of unknown function (DUF2589)
HKNOCMOD_01602	2.67e-111	-	-	-	KT	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	phosphorelay signal transduction system
HKNOCMOD_01603	1.75e-301	-	-	-	C	-	-	-	4 iron, 4 sulfur cluster binding
HKNOCMOD_01604	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
HKNOCMOD_01605	5.09e-211	-	-	-	K	-	-	-	Transcriptional regulator
HKNOCMOD_01606	2.21e-180	-	-	-	C	-	-	-	aldo keto reductase
HKNOCMOD_01607	1.31e-182	-	-	-	S	-	-	-	Alpha/beta hydrolase family
HKNOCMOD_01608	3.81e-255	-	-	-	S	ko:K06889	-	ko00000	X-Pro dipeptidyl-peptidase (S15 family)
HKNOCMOD_01609	5.36e-146	-	-	-	C	-	-	-	Carboxymuconolactone decarboxylase family
HKNOCMOD_01610	7.06e-117	-	-	-	C	-	-	-	Carboxymuconolactone decarboxylase family
HKNOCMOD_01611	2.19e-154	-	-	-	IQ	-	-	-	Short chain dehydrogenase
HKNOCMOD_01612	6.31e-11	corC_1	-	-	P	ko:K03699	-	ko00000,ko02042	Transporter associated domain
HKNOCMOD_01614	4.21e-137	-	-	-	J	ko:K05808	-	ko00000,ko03009	Sigma 54 modulation/S30EA ribosomal protein C terminus
HKNOCMOD_01616	2.17e-08	-	-	-	M	-	-	-	major outer membrane lipoprotein
HKNOCMOD_01617	0.0	-	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
HKNOCMOD_01619	1.7e-168	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	KR domain
HKNOCMOD_01620	1.11e-307	-	-	-	C	-	-	-	Sulfatase-modifying factor enzyme 1
HKNOCMOD_01621	4.53e-22	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HKNOCMOD_01622	1.15e-05	-	-	-	-	-	-	-	-
HKNOCMOD_01623	3.1e-124	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase activity
HKNOCMOD_01624	8.8e-222	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase activity
HKNOCMOD_01625	2.5e-200	miaA	2.5.1.75	-	J	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HKNOCMOD_01626	2.94e-184	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
HKNOCMOD_01627	1.04e-272	-	-	-	S	ko:K11941	-	ko00000,ko01000	transferase activity, transferring acyl groups other than amino-acyl groups
HKNOCMOD_01628	1.77e-142	-	-	-	S	-	-	-	Hexapeptide repeat of succinyl-transferase
HKNOCMOD_01629	2.56e-271	-	-	-	M	-	-	-	Glycosyl transferases group 1
HKNOCMOD_01630	7.04e-245	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HKNOCMOD_01631	0.0	-	-	-	S	-	-	-	polysaccharide biosynthetic process
HKNOCMOD_01633	8.07e-180	-	-	-	M	ko:K01991	ko02026,map02026	ko00000,ko00001,ko02000	polysaccharide export
HKNOCMOD_01634	0.0	gumC	-	-	DM	ko:K16554	ko05111,map05111	ko00000,ko00001,ko02000	PFAM lipopolysaccharide biosynthesis protein
HKNOCMOD_01635	7.48e-162	-	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	protein tyrosine phosphatase activity
HKNOCMOD_01636	9.76e-176	-	-	-	M	-	-	-	Bacterial sugar transferase
HKNOCMOD_01637	2.29e-178	wbyL	-	GT2	M	ko:K13002	-	ko00000,ko01000,ko01003,ko01005	transferase activity, transferring glycosyl groups
HKNOCMOD_01638	3.58e-284	lsgC	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HKNOCMOD_01639	3.65e-256	lsgC	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HKNOCMOD_01640	3.55e-278	gtf1	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	transferase activity, transferring glycosyl groups
HKNOCMOD_01641	6.8e-223	-	-	-	-	-	-	-	-
HKNOCMOD_01642	1.39e-258	-	-	-	M	ko:K02847,ko:K13009	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	-O-antigen
HKNOCMOD_01643	7.14e-191	-	-	-	S	-	-	-	Glycosyl transferase family 11
HKNOCMOD_01648	1.93e-21	-	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	HMGL-like
HKNOCMOD_01649	0.0	-	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	DHHA1 domain
HKNOCMOD_01650	0.0	hyl	2.3.1.48, 3.2.1.169, 3.2.1.35	GH84	G	ko:K01197,ko:K15719	ko00531,ko01100,ko04931,map00531,map01100,map04931	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	beta-N-acetylhexosaminidase activity
HKNOCMOD_01652	2.02e-220	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Zinc-uptake complex component A periplasmic
HKNOCMOD_01653	2.03e-91	-	-	-	-	-	-	-	-
HKNOCMOD_01654	4.67e-187	-	-	-	P	ko:K09820	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HKNOCMOD_01655	6.95e-183	-	-	-	P	ko:K09819	-	ko00000,ko00002,ko02000	FecCD transport family
HKNOCMOD_01656	3.54e-122	-	-	-	S	ko:K19411	-	ko00000	UvrB/uvrC motif
HKNOCMOD_01657	2.52e-240	-	2.7.14.1	-	E	ko:K19405	-	ko00000,ko01000	ATP:guanido phosphotransferase, C-terminal catalytic domain
HKNOCMOD_01658	0.0	-	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	C-terminal, D2-small domain, of ClpB protein
HKNOCMOD_01659	0.0	-	3.2.1.50	-	G	ko:K01205	ko00531,ko01100,ko04142,map00531,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko04147	Alpha-L-fucosidase
HKNOCMOD_01660	3.75e-61	-	-	-	P	ko:K03972	-	ko00000	Rhodanese Homology Domain
HKNOCMOD_01661	2.1e-201	-	-	-	Q	-	-	-	Fumarylacetoacetate (FAA) hydrolase family
HKNOCMOD_01662	0.0	-	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	HMGL-like
HKNOCMOD_01663	7.08e-221	-	-	-	CO	-	-	-	amine dehydrogenase activity
HKNOCMOD_01664	7.71e-85	-	-	-	S	ko:K09117	-	ko00000	Yqey-like protein
HKNOCMOD_01665	1.02e-163	-	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
HKNOCMOD_01666	6.94e-202	-	-	-	GM	-	-	-	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HKNOCMOD_01667	2.41e-232	-	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class I (W and Y)
HKNOCMOD_01668	1.56e-103	-	-	-	T	-	-	-	Universal stress protein family
HKNOCMOD_01669	1.45e-190	-	-	-	S	ko:K09769	-	ko00000	YmdB-like protein
HKNOCMOD_01670	1.01e-184	-	-	-	H	ko:K22132	-	ko00000,ko03016	ThiF family
HKNOCMOD_01671	9.9e-121	-	-	-	-	-	-	-	-
HKNOCMOD_01673	2.25e-229	-	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
HKNOCMOD_01674	3.09e-122	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
HKNOCMOD_01675	3.77e-289	kbl	2.3.1.29	-	E	ko:K00639	ko00260,map00260	ko00000,ko00001,ko01000,ko01007	Aminotransferase class I and II
HKNOCMOD_01676	0.0	-	-	-	KLT	-	-	-	Sulfatase-modifying factor enzyme 1
HKNOCMOD_01677	1.06e-182	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	AAA domain
HKNOCMOD_01678	0.0	-	-	-	S	ko:K07126	-	ko00000	beta-lactamase activity
HKNOCMOD_01685	3.27e-205	-	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil DNA glycosylase superfamily
HKNOCMOD_01686	3.86e-285	-	4.1.99.19	-	H	ko:K03150	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Biotin and Thiamin Synthesis associated domain
HKNOCMOD_01687	0.0	-	-	-	M	-	-	-	Sulfatase
HKNOCMOD_01688	7.58e-291	-	-	-	-	-	-	-	-
HKNOCMOD_01689	0.0	-	3.2.1.51	GH95	G	ko:K15923	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65, N-terminal domain
HKNOCMOD_01690	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF2851)
HKNOCMOD_01691	6.39e-119	-	-	-	T	-	-	-	STAS domain
HKNOCMOD_01692	5.04e-257	-	-	-	I	-	-	-	Prenyltransferase and squalene oxidase repeat
HKNOCMOD_01693	8.89e-77	-	-	-	M	-	-	-	Glycosyl transferases group 1
HKNOCMOD_01694	2.67e-272	-	-	-	M	-	-	-	Glycosyl transferase 4-like domain
HKNOCMOD_01695	2.38e-272	lsgC	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HKNOCMOD_01696	0.0	-	-	-	-	-	-	-	-
HKNOCMOD_01697	3.63e-111	-	-	-	S	ko:K03818	-	ko00000,ko01000	maltose O-acetyltransferase activity
HKNOCMOD_01698	2.63e-205	-	-	-	M	-	-	-	PFAM glycosyl transferase family 2
HKNOCMOD_01699	1.94e-224	-	-	-	M	-	-	-	Glycosyl transferase, family 2
HKNOCMOD_01700	1.42e-38	epsH	-	GT2	S	ko:K19425	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
HKNOCMOD_01701	9.02e-128	-	-	-	C	-	-	-	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HKNOCMOD_01702	6.17e-284	-	-	-	S	-	-	-	polysaccharide biosynthetic process
HKNOCMOD_01703	1.81e-80	-	-	-	C	-	-	-	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus
HKNOCMOD_01705	0.0	rnr	-	-	K	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HKNOCMOD_01706	7.34e-72	-	-	-	L	-	-	-	Cupin 2, conserved barrel domain protein
HKNOCMOD_01707	1.95e-127	-	-	-	S	-	-	-	Cobalamin adenosyltransferase
HKNOCMOD_01709	7.13e-295	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HKNOCMOD_01710	1.12e-213	-	-	-	K	-	-	-	LysR substrate binding domain
HKNOCMOD_01711	1.17e-271	-	-	-	S	-	-	-	tRNA-splicing ligase RtcB
HKNOCMOD_01712	0.0	-	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	transmembrane transport
HKNOCMOD_01714	1.02e-283	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HKNOCMOD_01715	2.57e-133	-	-	-	D	-	-	-	ErfK ybiS ycfS ynhG family protein
HKNOCMOD_01716	0.0	-	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Aconitase C-terminal domain
HKNOCMOD_01717	3.58e-168	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	PFAM N-acetylmuramoyl-L-alanine amidase family 2
HKNOCMOD_01721	0.0	-	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	Bacterial DNA topoisomeraes I ATP-binding domain
HKNOCMOD_01722	6.28e-102	-	-	-	-	-	-	-	-
HKNOCMOD_01723	0.0	-	2.1.1.107, 4.2.1.75	-	H	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase HemD
HKNOCMOD_01724	2.24e-101	-	-	-	S	-	-	-	peptidase
HKNOCMOD_01725	5.18e-172	-	-	-	S	ko:K06973	-	ko00000	Putative neutral zinc metallopeptidase
HKNOCMOD_01726	2.86e-97	-	-	-	S	-	-	-	peptidase
HKNOCMOD_01727	0.0	-	-	-	S	-	-	-	pathogenesis
HKNOCMOD_01728	0.0	-	-	-	V	ko:K18095	ko01501,ko02020,map01501,map02020	ko00000,ko00001,ko00002,ko01504,ko02000	AcrB/AcrD/AcrF family
HKNOCMOD_01729	4.94e-227	-	-	-	M	ko:K18094	ko01501,ko02020,map01501,map02020	ko00000,ko00001,ko00002,ko01504,ko02000	Biotin-lipoyl like
HKNOCMOD_01730	6.38e-191	-	-	-	K	-	-	-	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
HKNOCMOD_01731	1.13e-221	-	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
HKNOCMOD_01736	3.33e-19	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
HKNOCMOD_01738	5.15e-124	nuoI	1.6.5.3	-	C	ko:K00338	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HKNOCMOD_01739	1.04e-309	nuoH	1.6.5.3	-	C	ko:K00337	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
HKNOCMOD_01740	0.0	-	1.6.5.3	-	C	ko:K00336	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region
HKNOCMOD_01741	0.0	-	1.6.5.3	-	C	ko:K00335	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region
HKNOCMOD_01742	2.88e-142	-	1.6.5.3	-	C	ko:K00334	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Thioredoxin-like [2Fe-2S] ferredoxin
HKNOCMOD_01743	4.39e-307	nuoD	1.6.5.3	-	C	ko:K00333	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HKNOCMOD_01745	0.0	-	-	-	G	-	-	-	Polysaccharide deacetylase
HKNOCMOD_01746	0.0	-	-	-	P	-	-	-	Putative Na+/H+ antiporter
HKNOCMOD_01747	1.78e-140	-	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Lumazine binding domain
HKNOCMOD_01748	2.08e-204	-	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase (PrmA)
HKNOCMOD_01749	0.0	pmp21	-	-	T	-	-	-	pathogenesis
HKNOCMOD_01750	0.0	-	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	4-alpha-glucanotransferase
HKNOCMOD_01752	0.0	-	2.8.4.4	-	J	ko:K14441	-	ko00000,ko01000,ko03009	Uncharacterized protein family UPF0004
HKNOCMOD_01753	0.0	-	-	-	-	ko:K07403	-	ko00000	-
HKNOCMOD_01754	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HKNOCMOD_01755	0.0	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HKNOCMOD_01756	2.94e-184	-	3.4.13.22	-	M	ko:K08641	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-ala-D-ala dipeptidase
HKNOCMOD_01759	0.0	-	-	-	E	-	-	-	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HKNOCMOD_01760	0.0	-	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	tail specific protease
HKNOCMOD_01761	3.14e-213	-	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Cytidylyltransferase family
HKNOCMOD_01762	0.0	-	3.6.4.13	-	L	ko:K03579	-	ko00000,ko01000	ATP-dependent helicase C-terminal
HKNOCMOD_01763	0.0	-	-	-	P	ko:K03306	-	ko00000	phosphate transporter
HKNOCMOD_01764	5.06e-297	-	-	-	O	-	-	-	peroxiredoxin activity
HKNOCMOD_01765	0.0	-	2.7.7.19	-	J	ko:K00970	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Poly A polymerase head domain
HKNOCMOD_01766	0.0	-	-	-	G	-	-	-	Alpha amylase, catalytic domain
HKNOCMOD_01767	0.0	-	-	-	NU	ko:K02453	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02044	Bacterial type II and III secretion system protein
HKNOCMOD_01768	0.0	-	-	-	-	-	-	-	-
HKNOCMOD_01769	7.21e-183	-	-	-	S	ko:K09778	-	ko00000	Domain of unknown function (DUF374)
HKNOCMOD_01770	7.21e-203	folD	1.5.1.5, 3.5.4.9	-	H	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HKNOCMOD_01771	3.39e-181	-	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
HKNOCMOD_01772	2.24e-203	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HKNOCMOD_01773	1.99e-283	-	-	-	E	-	-	-	Transglutaminase-like superfamily
HKNOCMOD_01774	8.69e-261	-	-	-	J	ko:K05541	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HKNOCMOD_01775	5.35e-289	-	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	LytB protein
HKNOCMOD_01777	9.53e-43	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S20
HKNOCMOD_01778	6.98e-143	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HKNOCMOD_01779	0.0	-	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Thiamine pyrophosphate enzyme, central domain
HKNOCMOD_01780	1.4e-189	-	-	-	S	-	-	-	metallopeptidase activity
HKNOCMOD_01781	3.25e-223	-	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Phosphatidylserine decarboxylase
HKNOCMOD_01782	1.57e-151	-	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribulose-phosphate 3 epimerase family
HKNOCMOD_01783	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Leucyl-tRNA synthetase, Domain 2
HKNOCMOD_01784	0.0	-	-	-	P	-	-	-	Sulfatase
HKNOCMOD_01786	3.03e-300	-	4.1.1.96	-	E	ko:K13747	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	Pyridoxal-dependent decarboxylase, C-terminal sheet domain
HKNOCMOD_01787	0.0	-	4.1.1.19	-	E	ko:K01585	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Pyridoxal-dependent decarboxylase, pyridoxal binding domain
HKNOCMOD_01788	1.11e-266	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HKNOCMOD_01789	1.61e-184	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
HKNOCMOD_01790	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Beta galactosidase small chain
HKNOCMOD_01791	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase activity
HKNOCMOD_01792	0.0	rarA	-	-	L	ko:K07478	-	ko00000	MgsA AAA+ ATPase C terminal
HKNOCMOD_01793	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	PFAM Glycoside hydrolase, family 20, catalytic core
HKNOCMOD_01795	6.86e-295	-	2.7.1.11, 2.7.1.90	-	H	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions
HKNOCMOD_01796	6.37e-190	-	-	-	M	-	-	-	Carbohydrate esterase, sialic acid-specific acetylesterase
HKNOCMOD_01797	2.18e-269	-	-	-	K	-	-	-	Periplasmic binding protein-like domain
HKNOCMOD_01801	8.79e-263	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HKNOCMOD_01802	9.2e-247	-	3.1.21.4	-	L	ko:K01155	-	ko00000,ko01000,ko02048	Type III restriction enzyme res subunit
HKNOCMOD_01803	0.0	-	-	-	L	-	-	-	Type III restriction enzyme res subunit
HKNOCMOD_01804	1.28e-126	cobU	2.7.1.156, 2.7.7.62, 6.3.5.10	-	H	ko:K02231,ko:K02232	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	cobinamide kinase activity
HKNOCMOD_01805	1.12e-205	-	-	-	G	-	-	-	myo-inosose-2 dehydratase activity
HKNOCMOD_01806	9.36e-172	cobS	2.7.8.26	-	H	ko:K02233	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
HKNOCMOD_01807	2.08e-241	cobT	2.4.2.21	-	H	ko:K00768	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
HKNOCMOD_01808	9.12e-237	cobD	6.3.1.10	-	H	ko:K02227	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
HKNOCMOD_01809	2.91e-142	cobQ	-	-	H	-	-	-	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
HKNOCMOD_01810	1.97e-09	-	-	-	M	-	-	-	lipid A biosynthetic process
HKNOCMOD_01816	1.57e-306	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HKNOCMOD_01817	1.1e-258	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HKNOCMOD_01818	0.0	-	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Mur ligase middle domain
HKNOCMOD_01819	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HKNOCMOD_01820	0.0	-	3.4.16.4	-	M	ko:K03587	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011,ko03036	Penicillin-binding Protein dimerisation domain
HKNOCMOD_01822	0.0	rsmH	2.1.1.199	-	M	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HKNOCMOD_01823	4.54e-105	-	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HKNOCMOD_01824	1.76e-187	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
HKNOCMOD_01825	2.82e-154	-	-	-	S	-	-	-	UPF0126 domain
HKNOCMOD_01826	3.95e-13	-	-	-	S	-	-	-	Mac 1
HKNOCMOD_01827	3.46e-191	-	-	-	B	-	-	-	positive regulation of histone acetylation
HKNOCMOD_01828	9.02e-311	mnmE	-	-	J	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HKNOCMOD_01829	5.9e-258	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HKNOCMOD_01830	2.36e-249	xerD1	-	-	L	ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
HKNOCMOD_01831	0.0	-	-	-	P	ko:K07221	-	ko00000,ko02000	Phosphate-selective porin O and P
HKNOCMOD_01832	2.6e-160	rnc	3.1.26.3	-	K	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HKNOCMOD_01833	3.75e-121	actI	1.5.1.36	-	S	ko:K00484	ko00350,ko00740,ko01100,ko01120,ko01220,map00350,map00740,map01100,map01120,map01220	ko00000,ko00001,ko01000	FMN binding
HKNOCMOD_01834	8.69e-257	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HKNOCMOD_01835	3.33e-146	-	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
HKNOCMOD_01836	3.27e-142	-	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Cytidylate kinase
HKNOCMOD_01837	0.0	-	-	-	I	-	-	-	Acetyltransferase (GNAT) domain
HKNOCMOD_01838	8.13e-208	thiL	2.7.4.16	-	H	ko:K00946	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HKNOCMOD_01839	4.34e-202	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HKNOCMOD_01840	0.0	-	-	-	GK	-	-	-	carbohydrate kinase activity
HKNOCMOD_01841	0.0	-	-	-	KLT	-	-	-	Protein tyrosine kinase
HKNOCMOD_01843	2.18e-289	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HKNOCMOD_01844	1.6e-128	-	-	-	D	ko:K06287	-	ko00000	Maf-like protein
HKNOCMOD_01845	0.0	-	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
HKNOCMOD_01847	3.27e-259	-	-	-	M	ko:K07271	-	ko00000,ko01000	LICD family
HKNOCMOD_01848	0.0	-	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Alpha amylase, C-terminal all-beta domain
HKNOCMOD_01850	2.06e-93	-	-	-	S	ko:K02426	-	ko00000	Fe-S metabolism associated domain
HKNOCMOD_01851	1.92e-222	-	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HKNOCMOD_01852	0.0	-	-	-	P	-	-	-	Sulfatase
HKNOCMOD_01853	0.0	-	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HKNOCMOD_01854	8.72e-53	-	-	-	G	ko:K11189	-	ko00000,ko02000	PTS HPr component phosphorylation site
HKNOCMOD_01855	1.48e-221	hprK	-	-	T	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr)
HKNOCMOD_01856	0.0	-	-	-	E	-	-	-	Peptidase dimerisation domain
HKNOCMOD_01857	1.46e-207	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HKNOCMOD_01858	2.75e-137	-	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	5-formyltetrahydrofolate cyclo-ligase family
HKNOCMOD_01859	0.0	-	-	-	S	-	-	-	50S ribosome-binding GTPase
HKNOCMOD_01860	5.88e-163	-	-	-	S	ko:K06997	-	ko00000	Alanine racemase, N-terminal domain
HKNOCMOD_01861	1.88e-135	-	-	-	K	ko:K07735	-	ko00000,ko03000	Uncharacterized ACR, COG1678
HKNOCMOD_01862	1.43e-190	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
HKNOCMOD_01863	0.0	-	-	-	M	-	-	-	Glycosyl transferase family group 2
HKNOCMOD_01864	1.76e-201	-	-	-	-	-	-	-	-
HKNOCMOD_01865	6.43e-79	-	-	-	P	ko:K06195	-	ko00000	ApaG domain
HKNOCMOD_01866	1.95e-247	-	-	-	V	ko:K07452	-	ko00000,ko01000,ko02048	AAA domain (dynein-related subfamily)
HKNOCMOD_01867	4.25e-168	-	-	-	V	ko:K19147	-	ko00000,ko02048	McrBC 5-methylcytosine restriction system component
HKNOCMOD_01868	0.0	-	-	-	L	-	-	-	SNF2 family N-terminal domain
HKNOCMOD_01869	8.26e-106	-	-	-	K	-	-	-	Lrp/AsnC ligand binding domain
HKNOCMOD_01870	1.3e-285	-	-	-	E	ko:K10907	-	ko00000,ko01000,ko01007	Cys/Met metabolism PLP-dependent enzyme
HKNOCMOD_01871	1.3e-198	-	-	-	S	-	-	-	CAAX protease self-immunity
HKNOCMOD_01872	4.64e-150	-	-	-	S	-	-	-	DUF218 domain
HKNOCMOD_01873	0.0	-	6.1.1.14	-	J	ko:K01880	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Anticodon binding domain
HKNOCMOD_01874	1.16e-205	yeaE	-	-	S	-	-	-	aldo-keto reductase (NADP) activity
HKNOCMOD_01875	0.0	-	-	-	S	-	-	-	Oxygen tolerance
HKNOCMOD_01876	8.51e-42	-	-	-	S	ko:K07114	-	ko00000,ko02000	von Willebrand factor (vWF) type A domain
HKNOCMOD_01878	1.65e-110	gepA	-	-	K	-	-	-	Phage-associated protein
HKNOCMOD_01879	1.83e-170	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HKNOCMOD_01880	1.14e-133	thiE	2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17	-	H	ko:K00788,ko:K03147,ko:K14153	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HKNOCMOD_01881	3.59e-212	-	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
HKNOCMOD_01882	1.6e-307	-	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Cys/Met metabolism PLP-dependent enzyme
HKNOCMOD_01883	4.23e-99	-	-	-	K	-	-	-	Transcriptional regulator
HKNOCMOD_01884	4.05e-266	-	5.1.1.1	-	M	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HKNOCMOD_01886	9.08e-286	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	defense response to virus
HKNOCMOD_01887	0.0	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	defense response to virus
HKNOCMOD_01888	7.45e-231	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	maintenance of DNA repeat elements
HKNOCMOD_01889	1.51e-73	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HKNOCMOD_01890	1.63e-298	-	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	2-oxoacid dehydrogenases acyltransferase (catalytic domain)
HKNOCMOD_01891	1.11e-204	-	-	-	S	ko:K09949	-	ko00000	Protein of unknown function (DUF1009)
HKNOCMOD_01894	4.67e-91	-	-	-	-	-	-	-	-
HKNOCMOD_01895	2.78e-171	yyaQ	-	-	V	-	-	-	Protein conserved in bacteria
HKNOCMOD_01896	2.06e-191	-	-	-	M	-	-	-	Glycosyl transferase WecB/TagA/CpsF family
HKNOCMOD_01897	3.71e-190	-	3.1.4.55	-	S	ko:K06167	ko00440,map00440	ko00000,ko00001,ko01000	Metallo-beta-lactamase superfamily
HKNOCMOD_01898	0.0	-	-	-	L	ko:K03631	-	ko00000,ko03400	RecF/RecN/SMC N terminal domain
HKNOCMOD_01899	0.0	-	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
HKNOCMOD_01900	3.19e-241	-	-	-	G	-	-	-	Glycosyl hydrolases family 16
HKNOCMOD_01901	9.29e-132	-	-	-	J	ko:K02356	-	ko00000,ko03012	Elongation factor P (EF-P) OB domain
HKNOCMOD_01902	2.42e-105	-	-	-	S	-	-	-	ACT domain protein
HKNOCMOD_01903	4.8e-313	-	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
HKNOCMOD_01904	3.06e-85	-	-	-	M	ko:K03282	-	ko00000,ko02000	Large-conductance mechanosensitive channel, MscL
HKNOCMOD_01905	8.34e-277	-	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Alkaline phosphatase homologues
HKNOCMOD_01906	4.93e-286	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HKNOCMOD_01907	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycoside hydrolase, family 20, catalytic core
HKNOCMOD_01908	8.88e-268	-	-	-	G	-	-	-	M42 glutamyl aminopeptidase
HKNOCMOD_01910	1.96e-121	ngr	-	-	C	-	-	-	Rubrerythrin
HKNOCMOD_01912	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF1705)
HKNOCMOD_01913	0.0	-	-	-	M	-	-	-	Glycosyl Hydrolase Family 88
HKNOCMOD_01914	0.0	-	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Anaerobic ribonucleoside-triphosphate reductase
HKNOCMOD_01915	1.09e-42	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	CTP reductase activity
HKNOCMOD_01916	1.15e-183	-	1.97.1.4	-	O	ko:K04069	-	ko00000,ko01000	Radical SAM superfamily
HKNOCMOD_01917	0.0	-	-	-	P	ko:K14445	-	ko00000,ko02000	Citrate transporter
HKNOCMOD_01918	0.0	-	-	-	T	-	-	-	Histidine kinase
HKNOCMOD_01919	1.28e-108	-	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	cheY-homologous receiver domain
HKNOCMOD_01920	0.0	-	-	-	P	ko:K07085	-	ko00000	Predicted Permease Membrane Region
HKNOCMOD_01921	1.62e-25	-	-	-	M	ko:K13730	ko05100,map05100	ko00000,ko00001	leucine-rich repeat-containing protein typical subtype
HKNOCMOD_01926	1.01e-199	supH	-	-	Q	-	-	-	phosphatase activity
HKNOCMOD_01928	5.49e-85	nuoA	1.6.5.3	-	C	ko:K00330	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HKNOCMOD_01929	1.96e-273	-	-	-	G	-	-	-	Major Facilitator Superfamily
HKNOCMOD_01934	8.52e-37	-	-	-	K	-	-	-	sequence-specific DNA binding
HKNOCMOD_01935	4.59e-169	-	-	-	S	-	-	-	Pfam:HipA_N
HKNOCMOD_01936	1.35e-75	-	-	-	S	-	-	-	Protein of unknown function (Hypoth_ymh)
HKNOCMOD_01941	6.52e-46	yfjQ	-	-	S	-	-	-	Domain of unknown function (DUF932)
HKNOCMOD_01942	1.24e-103	-	-	-	V	-	-	-	site-specific DNA-methyltransferase (adenine-specific) activity
HKNOCMOD_01945	9.64e-63	-	-	-	L	-	-	-	PD-(D/E)XK nuclease superfamily
HKNOCMOD_01946	3.82e-19	-	-	-	L	-	-	-	PD-(D/E)XK nuclease superfamily
HKNOCMOD_01947	7.8e-37	-	-	-	-	-	-	-	-
HKNOCMOD_01948	8e-16	-	-	-	S	-	-	-	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
HKNOCMOD_01949	5.57e-51	-	-	-	K	-	-	-	Pfam:DUF955
HKNOCMOD_01952	9.26e-07	-	-	-	S	-	-	-	TM2 domain
HKNOCMOD_01956	5.4e-59	-	-	-	S	ko:K07126	-	ko00000	beta-lactamase activity
HKNOCMOD_01958	1.29e-121	-	-	-	S	-	-	-	Virulence protein RhuM family
HKNOCMOD_01959	2.3e-164	-	-	-	K	-	-	-	filamentation induced by cAMP protein Fic
HKNOCMOD_01961	1.44e-45	-	-	-	S	-	-	-	von Willebrand factor type A domain
HKNOCMOD_01962	5.88e-06	-	-	-	KLT	-	-	-	Lanthionine synthetase C-like protein
HKNOCMOD_01966	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HKNOCMOD_01967	2.91e-38	-	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L35
HKNOCMOD_01968	5.25e-79	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HKNOCMOD_01969	0.0	-	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	Peptidase family M50
HKNOCMOD_01972	0.0	-	-	-	L	-	-	-	UvrD/REP helicase N-terminal domain
HKNOCMOD_01973	0.0	-	-	-	L	-	-	-	PD-(D/E)XK nuclease superfamily
HKNOCMOD_01974	1.7e-208	MA20_36650	-	-	EG	-	-	-	spore germination
HKNOCMOD_01975	3.48e-71	xerD1	-	-	L	ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
HKNOCMOD_01977	6.86e-291	-	-	-	V	-	-	-	Type II restriction enzyme, methylase
HKNOCMOD_01978	7.22e-269	-	-	-	KL	-	-	-	Helicase
HKNOCMOD_01979	1.1e-73	-	-	-	P	-	-	-	T5orf172
HKNOCMOD_01980	0.0	-	-	-	S	-	-	-	Alpha-2-macroglobulin family
HKNOCMOD_01981	9.88e-283	-	-	-	C	-	-	-	Iron-containing alcohol dehydrogenase
HKNOCMOD_01983	1.6e-120	-	2.1.1.63	-	L	ko:K00567	-	ko00000,ko01000,ko03400	6-O-methylguanine DNA methyltransferase, DNA binding domain
HKNOCMOD_01986	5.98e-212	-	-	-	-	-	-	-	-
HKNOCMOD_01987	7.58e-141	-	-	-	O	-	-	-	Glycoprotease family
HKNOCMOD_01988	1.17e-271	-	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Citrate synthase, C-terminal domain
HKNOCMOD_01989	2.76e-77	-	-	-	S	-	-	-	Predicted membrane protein (DUF2238)
HKNOCMOD_01990	1.02e-107	-	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HKNOCMOD_01991	1.18e-138	-	-	-	L	-	-	-	RNase_H superfamily
HKNOCMOD_01992	6.68e-103	smpB	-	-	O	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HKNOCMOD_01993	1.5e-44	-	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	RNA polymerase activity
HKNOCMOD_01994	1.43e-135	-	5.4.99.20	-	J	ko:K06181	-	ko00000,ko01000,ko03009	RNA pseudouridylate synthase
HKNOCMOD_01995	2.75e-209	-	-	-	-	-	-	-	-
HKNOCMOD_01996	3.73e-104	-	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	NDK
HKNOCMOD_01997	2.08e-202	-	-	-	S	-	-	-	Glycosyltransferase like family 2
HKNOCMOD_01998	4.12e-225	-	-	-	M	-	-	-	Glycosyl transferase family 2
HKNOCMOD_01999	3.51e-07	-	-	-	NU	-	-	-	Prokaryotic N-terminal methylation motif
HKNOCMOD_02000	1.2e-283	-	-	-	NU	ko:K02653	-	ko00000,ko02035,ko02044	Type II secretion system (T2SS), protein F
HKNOCMOD_02001	0.0	-	-	-	NU	ko:K02652	-	ko00000,ko02035,ko02044	Type II secretion system (T2SS), protein E, N-terminal domain
HKNOCMOD_02002	0.0	-	-	-	NU	ko:K02652	-	ko00000,ko02035,ko02044	Type II/IV secretion system protein
HKNOCMOD_02003	2.97e-244	-	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HKNOCMOD_02004	8.12e-110	-	-	-	S	-	-	-	Control of competence regulator ComK, YlbF/YmcA
HKNOCMOD_02005	6.39e-280	-	2.6.1.1	-	E	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	DegT/DnrJ/EryC1/StrS aminotransferase family
HKNOCMOD_02006	0.0	murJ	-	-	S	ko:K03980	-	ko00000,ko01011,ko02000	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
HKNOCMOD_02007	1.26e-271	-	-	-	IM	-	-	-	Cytidylyltransferase-like
HKNOCMOD_02008	1.74e-157	-	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	Iron/manganese superoxide dismutases, alpha-hairpin domain
HKNOCMOD_02009	0.0	-	-	-	S	-	-	-	Glycosyl hydrolase-like 10
HKNOCMOD_02010	5.15e-167	-	-	-	S	ko:K06898	-	ko00000	AIR carboxylase
HKNOCMOD_02011	3.66e-186	-	-	-	L	ko:K06864	-	ko00000	tRNA processing
HKNOCMOD_02012	1.26e-286	larC	4.99.1.12	-	S	ko:K09121	-	ko00000,ko01000	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
HKNOCMOD_02013	1.07e-238	-	2.5.1.90	-	H	ko:K02523	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Polyprenyl synthetase
HKNOCMOD_02014	0.0	-	-	-	E	ko:K03305	-	ko00000	POT family
HKNOCMOD_02015	0.0	-	5.2.1.8	-	O	ko:K03770	-	ko00000,ko01000,ko03110	PPIC-type PPIASE domain
HKNOCMOD_02016	2.39e-126	-	-	-	S	-	-	-	Pfam:DUF59
HKNOCMOD_02017	2.59e-107	-	-	-	-	-	-	-	-
HKNOCMOD_02019	3.12e-219	-	-	-	E	-	-	-	Domain of unknown function (DUF3472)
HKNOCMOD_02020	2.71e-316	nuoN	1.6.5.3	-	C	ko:K00343	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HKNOCMOD_02021	0.0	-	1.6.5.3	-	C	ko:K00342	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Proton-conducting membrane transporter
HKNOCMOD_02022	0.0	-	1.6.5.3	-	CP	ko:K00341	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus
HKNOCMOD_02023	6.01e-61	nuoK	1.6.5.3	-	C	ko:K00340	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HKNOCMOD_02025	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Glycosyl hydrolase family 36 N-terminal domain
HKNOCMOD_02026	1.43e-52	himA	-	-	L	ko:K03530,ko:K04764,ko:K05788	-	ko00000,ko03032,ko03036,ko03400	regulation of translation
HKNOCMOD_02027	0.0	-	-	-	-	-	-	-	-
HKNOCMOD_02028	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
HKNOCMOD_02029	1.14e-186	-	-	-	V	-	-	-	AAA domain
HKNOCMOD_02030	6.99e-78	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
HKNOCMOD_02031	1.57e-26	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HKNOCMOD_02032	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	COG0286 Type I restriction-modification system methyltransferase subunit
HKNOCMOD_02035	1.76e-298	-	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	tRNA (Uracil-5-)-methyltransferase
HKNOCMOD_02036	0.0	miaB	2.8.4.3	-	J	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HKNOCMOD_02037	0.0	-	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein
HKNOCMOD_02038	4.47e-256	-	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
HKNOCMOD_02039	2.33e-162	-	-	-	P	ko:K07089	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
HKNOCMOD_02040	3.84e-37	-	-	-	CO	-	-	-	PFAM cytochrome c biogenesis protein, transmembrane region
HKNOCMOD_02041	2.78e-22	-	-	-	CO	-	-	-	TIGRFAM small redox-active disulfide protein 2
HKNOCMOD_02042	1.68e-22	-	-	-	K	-	-	-	SMART regulatory protein ArsR
HKNOCMOD_02043	2.72e-194	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HKNOCMOD_02044	1.73e-307	-	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HKNOCMOD_02045	0.0	-	-	-	-	-	-	-	-
HKNOCMOD_02046	2.5e-163	-	-	-	S	-	-	-	SWIM zinc finger
HKNOCMOD_02047	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Argininosuccinate lyase C-terminal
HKNOCMOD_02048	0.0	-	-	-	U	ko:K03321	-	ko00000,ko02000	Sulfate permease family
HKNOCMOD_02049	5.07e-125	-	-	-	-	-	-	-	-
HKNOCMOD_02050	1.04e-109	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HKNOCMOD_02052	0.0	-	-	-	S	-	-	-	Carbohydrate esterase, sialic acid-specific acetylesterase
HKNOCMOD_02062	8.36e-118	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Low molecular weight phosphatase family
HKNOCMOD_02063	0.0	-	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	IMP dehydrogenase / GMP reductase domain
HKNOCMOD_02064	0.0	-	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	GMP synthase C terminal domain
HKNOCMOD_02065	1.04e-175	dam	2.1.1.72	-	H	ko:K06223	ko03430,map03430	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	D12 class N6 adenine-specific DNA methyltransferase
HKNOCMOD_02067	6.64e-51	-	3.1.21.4	-	L	ko:K01155	-	ko00000,ko01000,ko02048	Recognizes the double-stranded unmethylated sequence GATC and cleaves before G-1
HKNOCMOD_02068	8.37e-232	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HKNOCMOD_02069	1.06e-127	-	-	-	-	-	-	-	-
HKNOCMOD_02070	1.19e-256	-	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HKNOCMOD_02072	1.15e-151	-	-	-	NU	-	-	-	Prokaryotic N-terminal methylation motif
HKNOCMOD_02073	6.35e-84	-	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase SecG subunit
HKNOCMOD_02074	9e-65	panD	4.1.1.11	-	H	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HKNOCMOD_02075	7.89e-217	-	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin kinase
HKNOCMOD_02076	9.36e-171	truB	5.4.99.25	-	J	ko:K03177	-	ko00000,ko01000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HKNOCMOD_02077	2.96e-241	-	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain
HKNOCMOD_02079	1.03e-207	lpxG	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase
HKNOCMOD_02080	2.15e-242	-	-	-	H	-	-	-	PFAM glycosyl transferase family 8
HKNOCMOD_02081	3.23e-247	-	-	-	S	-	-	-	Glycosyltransferase like family 2
HKNOCMOD_02082	1.57e-234	-	-	GT9	M	ko:K02843,ko:K02849	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	ADP-heptose-lipopolysaccharide heptosyltransferase activity
HKNOCMOD_02083	1.31e-244	-	5.1.3.20	-	M	ko:K03274	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	3-beta hydroxysteroid dehydrogenase/isomerase family
HKNOCMOD_02084	2.07e-283	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HKNOCMOD_02085	3.32e-201	-	-	-	-	-	-	-	-
HKNOCMOD_02086	7.62e-305	-	-	-	M	-	-	-	Glycosyl transferases group 1
HKNOCMOD_02087	8.25e-250	-	-	-	S	-	-	-	Glycosyltransferase family 10 (fucosyltransferase) C-term
HKNOCMOD_02088	0.0	-	-	-	I	-	-	-	Acyltransferase family
HKNOCMOD_02089	8.63e-253	-	-	-	S	-	-	-	Glycosyltransferase family 10 (fucosyltransferase) C-term
HKNOCMOD_02091	0.0	-	-	-	P	-	-	-	Citrate transporter
HKNOCMOD_02093	5.39e-111	-	-	-	S	ko:K08999	-	ko00000	Bifunctional nuclease
HKNOCMOD_02094	5.58e-110	-	-	-	S	-	-	-	Bacterial transferase hexapeptide (six repeats)
HKNOCMOD_02095	0.0	-	-	-	E	-	-	-	Transglutaminase-like
HKNOCMOD_02096	1.25e-157	-	-	-	C	-	-	-	Nitroreductase family
HKNOCMOD_02098	0.0	-	3.2.1.23	-	G	ko:K01190,ko:K12308	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolases family 35
HKNOCMOD_02099	2.46e-177	-	-	-	CH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
HKNOCMOD_02100	8.28e-236	-	-	-	CH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
HKNOCMOD_02101	9.53e-288	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
HKNOCMOD_02102	5.67e-315	hsrA	-	-	EGP	-	-	-	Major facilitator Superfamily
HKNOCMOD_02103	7.17e-104	yciA	-	-	I	ko:K10806	ko01040,map01040	ko00000,ko00001,ko01000,ko01004	acyl-coa hydrolase
HKNOCMOD_02106	1.26e-206	-	-	-	IQ	-	-	-	KR domain
HKNOCMOD_02107	1.05e-256	-	-	-	M	-	-	-	Alginate lyase
HKNOCMOD_02108	5.31e-115	-	-	-	L	-	-	-	Staphylococcal nuclease homologues
HKNOCMOD_02111	2e-120	-	-	-	K	-	-	-	ParB domain protein nuclease
HKNOCMOD_02112	0.0	-	-	-	S	-	-	-	Phosphoadenosine phosphosulfate reductase
HKNOCMOD_02115	2.64e-267	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HKNOCMOD_02116	8.44e-266	-	-	-	E	-	-	-	FAD dependent oxidoreductase
HKNOCMOD_02117	4.93e-210	-	-	-	S	-	-	-	Rhomboid family
HKNOCMOD_02118	0.0	-	-	-	O	ko:K07391	-	ko00000	Magnesium chelatase, subunit ChlI C-terminal
HKNOCMOD_02119	3.57e-06	-	-	-	-	-	-	-	-
HKNOCMOD_02121	0.0	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Cys/Met metabolism PLP-dependent enzyme
HKNOCMOD_02122	1.8e-311	pqqE	-	-	C	ko:K06139	-	ko00000	SMART Elongator protein 3 MiaB NifB
HKNOCMOD_02123	8.71e-258	pqqE	-	-	C	ko:K06139	-	ko00000	SMART Elongator protein 3 MiaB NifB
HKNOCMOD_02125	4.99e-101	-	-	-	-	-	-	-	-
HKNOCMOD_02126	8.08e-236	gpsA	1.1.1.94	-	C	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
HKNOCMOD_02127	4.34e-152	-	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Glycerol-3-phosphate acyltransferase
HKNOCMOD_02128	1.02e-187	pppL	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	protein serine/threonine phosphatase activity
HKNOCMOD_02129	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class II (D, K and N)
HKNOCMOD_02130	0.0	-	1.2.7.1	-	C	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HKNOCMOD_02131	2.19e-100	manC	-	-	S	-	-	-	Cupin domain
HKNOCMOD_02132	3.2e-70	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HKNOCMOD_02133	0.0	-	-	-	G	-	-	-	Domain of unknown function (DUF4091)
HKNOCMOD_02134	8.64e-177	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HKNOCMOD_02136	0.0	-	-	-	P	-	-	-	Cation transport protein
HKNOCMOD_02137	3.67e-161	-	-	-	P	ko:K03499	-	ko00000,ko02000	TrkA-N domain
HKNOCMOD_02138	0.0	-	3.6.4.13	-	L	ko:K03578	-	ko00000,ko01000	Oligonucleotide/oligosaccharide-binding (OB)-fold
HKNOCMOD_02139	1.18e-109	-	2.2.1.6	-	E	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	ACT domain
HKNOCMOD_02140	0.0	-	-	-	O	-	-	-	Trypsin
HKNOCMOD_02141	6.78e-270	-	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III, delta subunit
HKNOCMOD_02142	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HKNOCMOD_02143	1.03e-262	-	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	RibD C-terminal domain
HKNOCMOD_02144	1.63e-156	-	-	-	M	-	-	-	Bacterial transferase hexapeptide (six repeats)
HKNOCMOD_02146	4.85e-257	-	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HKNOCMOD_02148	1.24e-206	-	3.3.1.1	-	H	ko:K01251	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	adenosylhomocysteinase activity
HKNOCMOD_02149	0.0	-	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	UvrD-like helicase C-terminal domain
HKNOCMOD_02150	7.64e-307	-	-	-	M	-	-	-	OmpA family
HKNOCMOD_02151	0.0	-	6.3.2.45	-	M	ko:K02558	-	ko00000,ko01000	Mur ligase family, catalytic domain
HKNOCMOD_02152	6.55e-221	-	-	-	E	-	-	-	Phosphoserine phosphatase
HKNOCMOD_02153	5.19e-170	-	-	-	S	ko:K06861	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HKNOCMOD_02156	3.87e-197	-	2.5.1.55	-	M	ko:K01627	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	DAHP synthetase I family
HKNOCMOD_02157	4.39e-170	cbiX	4.99.1.3	-	S	ko:K03795	ko00860,ko01100,ko01120,map00860,map01100,map01120	ko00000,ko00001,ko01000	sirohydrochlorin cobaltochelatase activity
HKNOCMOD_02158	5.88e-163	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S2
HKNOCMOD_02159	2.05e-198	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HKNOCMOD_02160	2.65e-174	-	-	-	E	-	-	-	ATPases associated with a variety of cellular activities
HKNOCMOD_02162	7.19e-281	-	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	3-dehydroquinate synthase
HKNOCMOD_02163	0.0	-	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
HKNOCMOD_02164	0.0	-	-	-	O	-	-	-	Trypsin
HKNOCMOD_02165	1.95e-271	-	-	-	-	-	-	-	-
HKNOCMOD_02166	3.6e-145	-	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Aconitase C-terminal domain
HKNOCMOD_02167	0.0	-	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Aconitase family (aconitate hydratase)
HKNOCMOD_02168	7.14e-141	-	2.3.1.181	-	H	ko:K03801	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Biotin/lipoate A/B protein ligase family
HKNOCMOD_02169	1.92e-238	-	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Ami_3
HKNOCMOD_02170	1.15e-238	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HKNOCMOD_02171	2.55e-216	-	-	-	M	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	POTRA domain, FtsQ-type
HKNOCMOD_02172	2.79e-226	ddl	6.3.2.4	-	M	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	D-ala D-ala ligase N-terminus
HKNOCMOD_02173	0.0	murB	-	-	M	-	-	-	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain
HKNOCMOD_02174	1.07e-264	-	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HKNOCMOD_02175	1.33e-277	-	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Cell cycle protein
HKNOCMOD_02176	1.64e-91	mltD	-	CBM50	M	ko:K08307,ko:K12204,ko:K19224	-	ko00000,ko01000,ko01002,ko01011,ko02044	LysM domain
HKNOCMOD_02177	8.57e-33	-	-	-	M	-	-	-	self proteolysis
HKNOCMOD_02179	2.31e-21	-	-	-	M	-	-	-	self proteolysis
HKNOCMOD_02180	3.71e-187	-	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	2Fe-2S iron-sulfur cluster binding domain
HKNOCMOD_02181	0.0	-	1.3.5.1, 1.3.5.4	-	C	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	Fumarate reductase flavoprotein C-term
HKNOCMOD_02182	4.83e-163	-	-	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002	-
HKNOCMOD_02183	2.56e-55	-	-	-	-	-	-	-	-
HKNOCMOD_02184	1.43e-194	-	-	-	S	ko:K07051	-	ko00000	TatD related DNase
HKNOCMOD_02185	7.45e-49	XK27_09985	-	-	S	-	-	-	Protein of unknown function (DUF1232)
HKNOCMOD_02187	0.0	-	-	-	T	-	-	-	pathogenesis
HKNOCMOD_02189	1.39e-08	cwlD	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	N-Acetylmuramoyl-L-alanine amidase
HKNOCMOD_02196	1.08e-41	-	-	-	L	ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
HKNOCMOD_02201	0.0	-	4.2.1.2	-	C	ko:K01676	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible hydration of fumarate to (S)- malate
HKNOCMOD_02203	5.32e-108	-	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	6-pyruvoyl tetrahydropterin synthase
HKNOCMOD_02205	0.0	-	3.2.1.52	GH20	G	ko:K01207,ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko01501,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map01501,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycoside hydrolase, family 20, catalytic core
HKNOCMOD_02206	7.6e-303	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HKNOCMOD_02207	3.4e-227	-	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Quinolinate synthetase A protein
HKNOCMOD_02208	2.9e-254	-	-	-	S	-	-	-	Putative S-adenosyl-L-methionine-dependent methyltransferase
HKNOCMOD_02211	2.6e-20	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
HKNOCMOD_02212	2.28e-12	-	-	-	K	-	-	-	Helix-turn-helix diphteria tox regulatory element
HKNOCMOD_02214	5.37e-106	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
HKNOCMOD_02215	1.09e-33	-	-	-	S	-	-	-	Protein of unknown function (DUF3780)
HKNOCMOD_02216	5.95e-237	-	-	-	S	ko:K06922	-	ko00000	Protein of unknown function (DUF499)
HKNOCMOD_02219	0.0	-	-	-	S	-	-	-	inositol 2-dehydrogenase activity
HKNOCMOD_02220	1.84e-284	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
HKNOCMOD_02221	4.21e-216	-	3.4.11.10, 3.4.11.6	-	DZ	ko:K19701	-	ko00000,ko01000,ko01002	aminopeptidase activity
HKNOCMOD_02222	5.48e-273	ycaD	-	-	EGP	ko:K08219	-	ko00000,ko02000	Major facilitator Superfamily
HKNOCMOD_02223	0.0	-	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	Sigma-54 factor, Activator interacting domain (AID)
HKNOCMOD_02224	2.71e-175	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HKNOCMOD_02225	1.05e-161	-	-	-	S	-	-	-	Phenazine biosynthesis-like protein
HKNOCMOD_02227	7.82e-134	mntP	-	-	P	-	-	-	manganese ion transmembrane transporter activity
HKNOCMOD_02228	0.0	-	-	-	-	-	-	-	-
HKNOCMOD_02229	2.39e-295	-	-	-	-	-	-	-	-
HKNOCMOD_02230	0.0	-	-	-	L	ko:K07478	-	ko00000	MgsA AAA+ ATPase C terminal
HKNOCMOD_02233	1.37e-220	-	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	NmrA-like family
HKNOCMOD_02234	8.25e-273	-	-	-	S	-	-	-	Phosphotransferase enzyme family
HKNOCMOD_02235	9.25e-215	-	-	-	JM	-	-	-	Nucleotidyl transferase
HKNOCMOD_02237	3.39e-157	-	-	-	S	-	-	-	Peptidase family M50
HKNOCMOD_02238	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Prolyl-tRNA synthetase, C-terminal
HKNOCMOD_02241	1.64e-190	-	-	-	E	-	-	-	haloacid dehalogenase-like hydrolase
HKNOCMOD_02242	7.24e-141	-	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S4/S9 N-terminal domain
HKNOCMOD_02243	3.5e-120	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HKNOCMOD_02244	1.11e-79	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HKNOCMOD_02245	1.25e-266	-	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Domain of unknown function (DUF1730)
HKNOCMOD_02246	3.12e-220	-	-	-	M	ko:K07276	-	ko00000	Mitochondrial fission ELM1
HKNOCMOD_02247	3.98e-247	-	-	-	M	-	-	-	Glycosyl transferase 4-like
HKNOCMOD_02248	1.47e-267	-	-	-	LU	ko:K04096	-	ko00000	DNA recombination-mediator protein A
HKNOCMOD_02249	5.53e-285	-	5.4.99.22	-	M	ko:K06178	-	ko00000,ko01000,ko03009	translation initiation factor activity
HKNOCMOD_02250	2.2e-134	-	-	-	U	ko:K03561	-	ko00000,ko02000	MotA/TolQ/ExbB proton channel family
HKNOCMOD_02251	1.05e-92	-	-	-	U	ko:K03559	-	ko00000,ko02000	Biopolymer transport protein ExbD/TolR
HKNOCMOD_02252	8.02e-130	-	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HKNOCMOD_02253	4.97e-292	-	3.2.1.1	GH57	G	ko:K07405	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolase family 57
HKNOCMOD_02254	3.66e-315	-	-	-	G	-	-	-	Glycosyl transferase 4-like domain
HKNOCMOD_02255	0.0	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolases family 31
HKNOCMOD_02257	2.1e-121	-	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
HKNOCMOD_02258	0.0	-	-	-	-	-	-	-	-
HKNOCMOD_02259	1.4e-238	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
HKNOCMOD_02260	0.0	-	-	-	S	-	-	-	ABC-type transport system involved in multi-copper enzyme maturation permease component
HKNOCMOD_02261	1.16e-207	-	-	-	S	-	-	-	Protein of unknown function DUF58
HKNOCMOD_02262	0.0	-	-	-	S	-	-	-	Aerotolerance regulator N-terminal
HKNOCMOD_02263	0.0	-	-	-	S	-	-	-	von Willebrand factor type A domain
HKNOCMOD_02264	5.81e-283	-	-	-	-	-	-	-	-
HKNOCMOD_02265	2.85e-259	-	4.1.2.48	-	E	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Beta-eliminating lyase
HKNOCMOD_02266	6.3e-78	-	-	-	K	-	-	-	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
HKNOCMOD_02267	9.81e-281	-	-	-	C	-	-	-	Aldo/keto reductase family
HKNOCMOD_02268	0.0	-	-	-	KLT	-	-	-	Protein tyrosine kinase
HKNOCMOD_02269	1.93e-138	-	-	-	K	ko:K03088	-	ko00000,ko03021	DNA-templated transcription, initiation
HKNOCMOD_02270	1.02e-196	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
HKNOCMOD_02272	8.73e-234	-	2.7.11.1	-	T	ko:K08884,ko:K12132,ko:K20333	ko02024,map02024	ko00000,ko00001,ko01000,ko01001	PFAM Formylglycine-generating sulfatase enzyme
HKNOCMOD_02274	2e-158	-	2.7.13.3	-	T	ko:K07646	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Osmosensitive K+ channel His kinase sensor domain
HKNOCMOD_02275	1.54e-87	-	2.7.13.3	-	T	ko:K07646	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Osmosensitive K+ channel His kinase sensor domain
HKNOCMOD_02277	2e-129	kdpC	3.6.3.12	-	P	ko:K01548	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
HKNOCMOD_02278	0.0	kdpB	3.6.3.12	-	P	ko:K01547	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
HKNOCMOD_02279	0.0	kdpA	3.6.3.12	-	P	ko:K01546	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
HKNOCMOD_02281	3.44e-19	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
HKNOCMOD_02286	3.11e-188	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
HKNOCMOD_02287	3.59e-87	-	-	-	S	ko:K09793	-	ko00000	Protein of unknown function (DUF456)
HKNOCMOD_02288	0.0	-	3.2.1.51	GH95	G	ko:K15923	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65, N-terminal domain
HKNOCMOD_02289	3.34e-102	-	3.2.1.51	GH95	G	ko:K15923	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65, N-terminal domain
HKNOCMOD_02290	3.69e-251	-	-	-	S	-	-	-	Peptidase family M28
HKNOCMOD_02291	4.53e-224	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HKNOCMOD_02292	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HKNOCMOD_02293	5.66e-183	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	Signal peptidase (SPase) II
HKNOCMOD_02294	1.55e-148	-	-	-	S	-	-	-	Protein of unknown function (DUF1573)
HKNOCMOD_02295	1.81e-113	-	-	-	P	-	-	-	Rhodanese-like domain
HKNOCMOD_02296	3.02e-295	-	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HKNOCMOD_02297	0.0	-	-	-	S	-	-	-	acetyltransferases and hydrolases with the alpha beta hydrolase fold
HKNOCMOD_02301	8.14e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HKNOCMOD_02302	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
HKNOCMOD_02303	1.5e-100	-	5.1.99.1	-	E	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Glyoxalase-like domain
HKNOCMOD_02304	0.0	-	2.1.3.15, 6.4.1.3	-	I	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Carboxyl transferase domain
HKNOCMOD_02306	5.64e-54	-	-	-	I	-	-	-	PFAM biotin lipoyl attachment domain-containing protein
HKNOCMOD_02307	0.0	-	4.1.1.3	-	C	ko:K01572	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	Na+-transporting oxaloacetate decarboxylase beta subunit
HKNOCMOD_02308	3.56e-187	-	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Biotin/lipoate A/B protein ligase family
HKNOCMOD_02309	0.0	-	-	-	C	-	-	-	Acetyl-CoA hydrolase/transferase C-terminal domain
HKNOCMOD_02312	2.73e-205	-	2.7.7.24	-	M	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HKNOCMOD_02313	4.37e-270	-	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Male sterility protein
HKNOCMOD_02314	4.6e-228	-	2.7.1.11	-	G	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Phosphofructokinase
HKNOCMOD_02315	2.72e-183	-	-	-	L	ko:K10800	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	uracil-dna glycosylase
HKNOCMOD_02316	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HKNOCMOD_02317	0.0	poxB	1.2.3.3, 1.2.5.1	-	EH	ko:K00156,ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Thiamine pyrophosphate enzyme, central domain
HKNOCMOD_02319	0.0	-	-	-	G	-	-	-	alpha-galactosidase
HKNOCMOD_02321	0.0	-	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
HKNOCMOD_02322	2.95e-262	mtrC	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HKNOCMOD_02323	0.0	-	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HKNOCMOD_02324	7.92e-306	-	-	-	P	ko:K14445	-	ko00000,ko02000	Citrate transporter
HKNOCMOD_02326	2.91e-175	-	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HKNOCMOD_02328	1.2e-169	-	-	-	S	-	-	-	PFAM Sel1 domain protein repeat-containing protein
HKNOCMOD_02331	0.0	-	-	-	L	-	-	-	DNA restriction-modification system
HKNOCMOD_02335	3.92e-115	-	-	-	-	-	-	-	-
HKNOCMOD_02336	4.46e-182	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HKNOCMOD_02338	1.56e-160	-	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HKNOCMOD_02339	2.04e-258	tdh	1.1.1.103	-	E	ko:K00060	ko00260,map00260	ko00000,ko00001,ko01000	Alcohol dehydrogenase GroES-like domain
HKNOCMOD_02340	0.0	-	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Carbohydrate phosphorylase
HKNOCMOD_02341	5.87e-180	-	-	-	P	ko:K10716	-	ko00000,ko02000	domain protein
HKNOCMOD_02342	1.28e-82	-	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	ArsC family
HKNOCMOD_02343	0.0	-	-	-	J	ko:K07576	-	ko00000	Beta-Casp domain
HKNOCMOD_02344	5.74e-54	tatA	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HKNOCMOD_02345	3.94e-243	-	-	-	S	-	-	-	PFAM Sel1 domain protein repeat-containing protein
HKNOCMOD_02346	2.18e-237	-	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	RNA pseudouridylate synthase
HKNOCMOD_02347	2.05e-28	-	-	-	-	-	-	-	-
HKNOCMOD_02348	5.45e-172	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	tRNA (Guanine-1)-methyltransferase
HKNOCMOD_02349	1.8e-237	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HKNOCMOD_02350	1.66e-87	-	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
HKNOCMOD_02351	0.0	-	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence
HKNOCMOD_02352	4.95e-134	-	-	-	C	-	-	-	Nitroreductase family
HKNOCMOD_02353	1.44e-109	-	-	-	S	-	-	-	Acetyltransferase (GNAT) family
HKNOCMOD_02358	7.29e-211	-	-	-	M	-	-	-	Peptidase family M23
HKNOCMOD_02359	5.87e-228	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
HKNOCMOD_02360	4.13e-183	panB	2.1.2.11	-	H	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
HKNOCMOD_02361	4.21e-121	-	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
HKNOCMOD_02362	4.14e-175	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Dihydrodipicolinate reductase, N-terminus
HKNOCMOD_02363	1.02e-203	dapA	4.3.3.7	-	EM	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Dihydrodipicolinate synthetase family
HKNOCMOD_02365	1.35e-76	-	-	-	D	-	-	-	T5orf172
HKNOCMOD_02384	9.42e-82	-	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	Belongs to the N(4) N(6)-methyltransferase family
HKNOCMOD_02387	4.44e-16	-	-	-	M	-	-	-	D-alanyl-D-alanine carboxypeptidase
HKNOCMOD_02391	1.18e-174	-	-	-	S	-	-	-	Terminase-like family
HKNOCMOD_02392	3.19e-37	-	-	-	L	-	-	-	Mu-like prophage protein gp29
HKNOCMOD_02405	1.52e-176	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
HKNOCMOD_02407	1.46e-85	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
HKNOCMOD_02411	1.07e-09	-	-	-	M	-	-	-	self proteolysis
HKNOCMOD_02412	3.62e-172	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
HKNOCMOD_02413	2.63e-84	-	-	-	M	-	-	-	Lysin motif
HKNOCMOD_02414	1.15e-198	-	-	-	L	ko:K03424	-	ko00000,ko01000	TatD related DNase
HKNOCMOD_02415	8.81e-267	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2219)
HKNOCMOD_02416	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Beta galactosidase small chain
HKNOCMOD_02417	2.66e-06	-	-	-	-	-	-	-	-
HKNOCMOD_02419	0.0	-	2.7.13.3	-	T	ko:K07646	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Osmosensitive K+ channel His kinase sensor domain
HKNOCMOD_02420	2.4e-167	-	-	-	T	ko:K07667	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
HKNOCMOD_02422	0.0	-	3.6.3.12	-	P	ko:K01546	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
HKNOCMOD_02423	0.0	-	3.6.3.12	-	P	ko:K01547	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
HKNOCMOD_02424	1.08e-127	-	3.6.3.12	-	P	ko:K01548	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
HKNOCMOD_02425	9.07e-73	-	-	-	S	-	-	-	PFAM Cupin 2 conserved barrel domain protein
HKNOCMOD_02426	5.23e-230	-	-	-	K	-	-	-	DNA-binding transcription factor activity
HKNOCMOD_02427	0.0	-	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	C-terminal, D2-small domain, of ClpB protein
HKNOCMOD_02431	0.0	-	2.6.1.66	-	E	ko:K00835	ko00290,ko01100,ko01110,ko01130,map00290,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko01007	Aminotransferase class I and II
HKNOCMOD_02432	2.47e-194	-	-	-	S	-	-	-	Domain of unknown function (DUF1732)
HKNOCMOD_02433	5.99e-143	-	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase homologues.
HKNOCMOD_02434	0.0	-	-	-	P	-	-	-	Citrate transporter
HKNOCMOD_02435	3.09e-208	-	-	-	J	ko:K01894	-	ko00000,ko01000,ko01007,ko03016	tRNA synthetases class I (E and Q), catalytic domain
HKNOCMOD_02438	8.52e-215	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
HKNOCMOD_02439	1.56e-169	-	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Type I 3-dehydroquinase
HKNOCMOD_02441	3.21e-217	-	-	-	-	-	-	-	-
HKNOCMOD_02442	2.14e-164	-	-	-	S	ko:K05810	-	ko00000,ko01000	Multi-copper polyphenol oxidoreductase laccase
HKNOCMOD_02443	1.1e-173	-	-	-	T	-	-	-	Outer membrane lipoprotein-sorting protein
HKNOCMOD_02444	1.96e-226	-	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
HKNOCMOD_02445	0.0	secD	-	-	U	ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HKNOCMOD_02447	4.27e-274	-	3.4.23.43	-	NOU	ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	Type IV leader peptidase family
HKNOCMOD_02448	1.38e-257	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Possible lysine decarboxylase
HKNOCMOD_02449	2.95e-262	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKNOCMOD_02450	4.19e-87	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HKNOCMOD_02451	1.54e-217	-	2.3.1.39	-	I	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Acyl transferase domain
HKNOCMOD_02453	1.1e-167	-	-	-	S	-	-	-	HAD-hyrolase-like
HKNOCMOD_02454	3.06e-286	-	-	-	S	ko:K11720	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Predicted permease YjgP/YjgQ family
HKNOCMOD_02455	9.56e-266	-	-	-	E	-	-	-	serine-type peptidase activity
HKNOCMOD_02456	3.91e-306	-	-	-	M	-	-	-	OmpA family
HKNOCMOD_02457	2.98e-214	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HKNOCMOD_02458	0.0	-	-	-	M	-	-	-	Peptidase M60-like family
HKNOCMOD_02459	2.87e-288	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HKNOCMOD_02460	0.0	-	-	-	KT	-	-	-	Sigma factor PP2C-like phosphatases
HKNOCMOD_02461	5.45e-162	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70 region 2
HKNOCMOD_02462	2.25e-240	-	-	-	S	-	-	-	Endonuclease/Exonuclease/phosphatase family
HKNOCMOD_02463	5.28e-153	-	-	-	NU	ko:K02457,ko:K08084	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02044	protein transport across the cell outer membrane
HKNOCMOD_02464	1.83e-188	-	-	-	-	-	-	-	-
HKNOCMOD_02465	1.72e-245	-	-	-	NU	-	-	-	Prokaryotic N-terminal methylation motif
HKNOCMOD_02466	4.68e-181	-	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Biotin/lipoate A/B protein ligase family
HKNOCMOD_02467	3.58e-238	-	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo/keto reductase family
HKNOCMOD_02468	0.0	hppA	3.6.1.1	-	C	ko:K15987	ko00190,map00190	ko00000,ko00001,ko01000	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane
HKNOCMOD_02471	0.0	-	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Anthranilate synthase component I, N terminal region
HKNOCMOD_02472	0.0	trpD	2.4.2.18, 4.1.3.27	-	E	ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HKNOCMOD_02473	3.61e-172	-	4.1.1.48	-	E	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Indole-3-glycerol phosphate synthase
HKNOCMOD_02474	4.88e-154	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	N-(5'phosphoribosyl)anthranilate (PRA) isomerase
HKNOCMOD_02475	3.31e-283	-	4.2.1.20	-	E	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HKNOCMOD_02476	2.05e-183	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HKNOCMOD_02477	0.0	-	-	-	T	-	-	-	pathogenesis
HKNOCMOD_02478	2.25e-91	-	-	-	O	-	-	-	response to oxidative stress
HKNOCMOD_02479	8.87e-291	-	2.3.1.31	-	E	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko01000	alpha/beta hydrolase fold
HKNOCMOD_02480	3.75e-64	-	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L36
HKNOCMOD_02481	0.0	-	2.3.1.241	-	M	ko:K02517	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Glycosyltransferase family 9 (heptosyltransferase)
HKNOCMOD_02482	5.66e-184	-	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	4Fe-4S single cluster domain
HKNOCMOD_02483	0.0	-	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
HKNOCMOD_02484	4.66e-299	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 2 family
HKNOCMOD_02485	8.33e-183	-	-	-	E	-	-	-	PFAM lipolytic protein G-D-S-L family
HKNOCMOD_02486	2.59e-77	-	-	-	EG	-	-	-	BNR repeat-like domain
HKNOCMOD_02487	0.0	-	-	-	EG	-	-	-	BNR repeat-like domain
HKNOCMOD_02488	0.0	legA	3.5.1.2	-	G	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	response to abiotic stimulus
HKNOCMOD_02489	1.56e-60	-	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Ribosomal protein S6
HKNOCMOD_02490	4.92e-209	-	1.1.1.262	-	H	ko:K00097	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Pyridoxal phosphate biosynthetic protein PdxA
HKNOCMOD_02493	3.37e-224	-	-	-	M	-	-	-	D-alanyl-D-alanine carboxypeptidase
HKNOCMOD_02494	3.82e-255	-	2.7.1.11, 2.7.1.90	-	G	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Phosphofructokinase
HKNOCMOD_02495	1.96e-219	-	-	-	L	-	-	-	Membrane
HKNOCMOD_02496	1.52e-173	zupT	-	-	P	ko:K07238	-	ko00000,ko02000	transporter
HKNOCMOD_02497	2.5e-234	-	-	-	CO	-	-	-	Protein of unknown function, DUF255
HKNOCMOD_02503	1.09e-12	-	-	-	K	ko:K07726	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
HKNOCMOD_02504	3.84e-33	-	-	-	M	-	-	-	Peptidoglycan-binding domain 1 protein
HKNOCMOD_02508	1.04e-54	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	thiamine diphosphate biosynthetic process