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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
IGHMFEHH_00002	1.56e-255	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Iron-containing alcohol dehydrogenase
IGHMFEHH_00004	1.21e-301	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
IGHMFEHH_00005	1.46e-178	-	-	-	C	-	-	-	Cytochrome c7 and related cytochrome c
IGHMFEHH_00006	0.0	-	-	-	C	ko:K00184	-	ko00000	4Fe-4S dicluster domain
IGHMFEHH_00008	0.0	-	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	RecG wedge domain
IGHMFEHH_00009	4.02e-166	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	PFAM N-acetylmuramoyl-L-alanine amidase family 2
IGHMFEHH_00010	0.0	pckG	4.1.1.32	-	C	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle
IGHMFEHH_00012	9.05e-85	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	4'-phosphopantetheinyl transferase superfamily
IGHMFEHH_00013	5.64e-173	pdxJ	2.6.99.2	-	H	ko:K03474	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
IGHMFEHH_00014	0.0	-	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	AICARFT/IMPCHase bienzyme
IGHMFEHH_00015	7.49e-95	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L9, N-terminal domain
IGHMFEHH_00016	1.81e-227	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
IGHMFEHH_00017	3.2e-209	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
IGHMFEHH_00018	1.5e-18	-	-	-	S	-	-	-	Lipocalin-like
IGHMFEHH_00020	8.77e-239	cbiM	-	-	P	ko:K02007,ko:K02009,ko:K16915	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt ion transport
IGHMFEHH_00021	2.42e-195	cbiQ	-	-	P	ko:K02007,ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transmembrane transporter activity
IGHMFEHH_00022	4.82e-179	cbiO	-	-	P	ko:K02006,ko:K02008,ko:K16784,ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPase activity
IGHMFEHH_00023	0.0	-	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	HELICc2
IGHMFEHH_00025	1.36e-207	ispE	2.7.1.148	-	I	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	GHMP kinases N terminal domain
IGHMFEHH_00026	0.0	-	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	TopoisomeraseII
IGHMFEHH_00027	1.06e-173	-	2.5.1.31	-	I	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IGHMFEHH_00028	2.41e-259	-	2.7.7.13	-	M	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
IGHMFEHH_00029	3.03e-96	-	-	-	L	ko:K07447	-	ko00000,ko01000	Likely ribonuclease with RNase H fold.
IGHMFEHH_00030	4.69e-236	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
IGHMFEHH_00031	1.45e-55	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L28 family
IGHMFEHH_00032	1.04e-49	-	-	-	-	-	-	-	-
IGHMFEHH_00033	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Alpha galactosidase A
IGHMFEHH_00034	1.84e-221	-	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
IGHMFEHH_00035	0.0	-	-	-	E	-	-	-	Aminotransferase class I and II
IGHMFEHH_00036	4.6e-305	-	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IGHMFEHH_00037	1.04e-78	divIC	-	-	D	ko:K05589,ko:K13052	-	ko00000,ko03036	cell cycle
IGHMFEHH_00038	0.0	-	-	-	P	-	-	-	Sulfatase
IGHMFEHH_00040	9.64e-153	-	-	-	K	-	-	-	Transcriptional regulator
IGHMFEHH_00041	2.5e-190	-	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
IGHMFEHH_00042	1.35e-236	-	1.1.1.86	-	E	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IGHMFEHH_00043	1.41e-119	-	-	-	M	ko:K03098	-	ko00000,ko04147	Lipocalin-like domain
IGHMFEHH_00044	1.58e-205	-	-	-	S	ko:K07071	-	ko00000	Domain of unknown function (DUF1731)
IGHMFEHH_00045	9.5e-201	-	-	-	O	-	-	-	stress-induced mitochondrial fusion
IGHMFEHH_00047	2.32e-239	-	-	-	E	-	-	-	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IGHMFEHH_00049	1.54e-218	-	-	-	S	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
IGHMFEHH_00050	1.62e-32	-	-	-	S	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
IGHMFEHH_00051	1.49e-237	-	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
IGHMFEHH_00052	0.0	-	-	-	-	-	-	-	-
IGHMFEHH_00053	1.78e-241	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
IGHMFEHH_00054	0.0	-	-	-	S	-	-	-	ABC-type transport system involved in multi-copper enzyme maturation permease component
IGHMFEHH_00055	3.19e-205	-	-	-	S	-	-	-	Protein of unknown function DUF58
IGHMFEHH_00056	0.0	-	-	-	S	-	-	-	Aerotolerance regulator N-terminal
IGHMFEHH_00057	0.0	-	-	-	S	-	-	-	von Willebrand factor type A domain
IGHMFEHH_00058	9.84e-291	-	-	-	-	-	-	-	-
IGHMFEHH_00059	5.75e-259	-	4.1.2.48	-	E	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Beta-eliminating lyase
IGHMFEHH_00060	2.51e-85	-	-	-	K	-	-	-	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
IGHMFEHH_00061	3.15e-277	-	-	-	C	-	-	-	Aldo/keto reductase family
IGHMFEHH_00062	0.0	-	-	-	KLT	-	-	-	Protein tyrosine kinase
IGHMFEHH_00063	1.93e-138	-	-	-	K	ko:K03088	-	ko00000,ko03021	DNA-templated transcription, initiation
IGHMFEHH_00064	1.02e-196	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
IGHMFEHH_00066	1.39e-230	-	2.7.11.1	-	T	ko:K08884,ko:K12132,ko:K20333	ko02024,map02024	ko00000,ko00001,ko01000,ko01001	PFAM Formylglycine-generating sulfatase enzyme
IGHMFEHH_00068	3.88e-263	-	2.7.13.3	-	T	ko:K07646	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Osmosensitive K+ channel His kinase sensor domain
IGHMFEHH_00069	2.54e-132	kdpC	3.6.3.12	-	P	ko:K01548	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
IGHMFEHH_00070	0.0	kdpB	3.6.3.12	-	P	ko:K01547	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
IGHMFEHH_00071	0.0	kdpA	3.6.3.12	-	P	ko:K01546	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
IGHMFEHH_00072	1.49e-28	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
IGHMFEHH_00080	0.0	-	-	-	D	ko:K03466	-	ko00000,ko03036	Ftsk_gamma
IGHMFEHH_00082	7.6e-145	-	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IGHMFEHH_00084	7.64e-137	rbr	-	-	C	-	-	-	Rubrerythrin
IGHMFEHH_00085	0.0	-	-	-	O	-	-	-	Cytochrome C assembly protein
IGHMFEHH_00087	0.0	-	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	Catalase
IGHMFEHH_00088	1.01e-45	-	-	-	S	-	-	-	R3H domain
IGHMFEHH_00090	0.0	-	1.2.1.88, 1.5.5.2	-	CE	ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko03000	Proline dehydrogenase
IGHMFEHH_00091	2.16e-285	-	-	-	S	-	-	-	Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units
IGHMFEHH_00092	1.38e-115	cas7c	-	-	L	ko:K19118	-	ko00000,ko02048	CRISPR-associated protein Cas7
IGHMFEHH_00093	9.67e-159	-	-	-	S	ko:K19117	-	ko00000,ko02048	TIGRFAM CRISPR-associated protein
IGHMFEHH_00094	1.06e-54	cas5d	-	-	S	ko:K19119	-	ko00000,ko02048	CRISPR-associated protein Cas5, Dvulg subtype
IGHMFEHH_00095	1.84e-156	-	-	-	L	ko:K07012	-	ko00000,ko01000,ko02048	helicase Cas3
IGHMFEHH_00096	1.97e-62	-	3.1.12.1	-	L	ko:K07464	-	ko00000,ko01000,ko02048	CRISPR-associated protein Cas4
IGHMFEHH_00097	2.12e-141	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IGHMFEHH_00098	2.15e-34	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IGHMFEHH_00100	0.0	-	-	-	I	-	-	-	PFAM Prenyltransferase squalene oxidase
IGHMFEHH_00101	1.7e-301	-	4.2.1.129, 5.4.99.17, 5.5.1.16	-	I	ko:K06045,ko:K17811	ko00909,ko01110,map00909,map01110	ko00000,ko00001,ko01000	PFAM Prenyltransferase squalene oxidase
IGHMFEHH_00102	6.5e-256	-	-	-	M	ko:K02022	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IGHMFEHH_00103	2.13e-158	-	-	-	S	-	-	-	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
IGHMFEHH_00105	5.12e-71	-	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Thioredoxin-like domain
IGHMFEHH_00106	7.81e-316	-	-	-	-	-	-	-	-
IGHMFEHH_00107	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class II (D, K and N)
IGHMFEHH_00109	0.0	-	-	-	T	-	-	-	pathogenesis
IGHMFEHH_00110	0.0	-	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
IGHMFEHH_00111	1.93e-116	ywrF	-	-	S	-	-	-	FMN binding
IGHMFEHH_00112	2.27e-86	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
IGHMFEHH_00113	0.0	-	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	UvrD-like helicase C-terminal domain
IGHMFEHH_00114	7.64e-307	-	-	-	M	-	-	-	OmpA family
IGHMFEHH_00115	0.0	-	6.3.2.45	-	M	ko:K02558	-	ko00000,ko01000	Mur ligase family, catalytic domain
IGHMFEHH_00116	6.55e-221	-	-	-	E	-	-	-	Phosphoserine phosphatase
IGHMFEHH_00117	6.31e-171	-	-	-	S	ko:K06861	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
IGHMFEHH_00120	1.64e-198	-	2.5.1.55	-	M	ko:K01627	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	DAHP synthetase I family
IGHMFEHH_00121	1.19e-175	cbiX	4.99.1.3	-	S	ko:K03795	ko00860,ko01100,ko01120,map00860,map01100,map01120	ko00000,ko00001,ko01000	sirohydrochlorin cobaltochelatase activity
IGHMFEHH_00122	5.88e-163	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S2
IGHMFEHH_00123	2.05e-198	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IGHMFEHH_00124	2.65e-174	-	-	-	E	-	-	-	ATPases associated with a variety of cellular activities
IGHMFEHH_00125	4.53e-284	-	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	3-dehydroquinate synthase
IGHMFEHH_00126	0.0	-	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
IGHMFEHH_00127	0.0	-	-	-	O	-	-	-	Trypsin
IGHMFEHH_00128	4.99e-274	-	-	-	-	-	-	-	-
IGHMFEHH_00129	8.49e-144	-	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Aconitase C-terminal domain
IGHMFEHH_00130	0.0	-	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Aconitase family (aconitate hydratase)
IGHMFEHH_00131	1.68e-139	-	2.3.1.181	-	H	ko:K03801	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Biotin/lipoate A/B protein ligase family
IGHMFEHH_00132	6.69e-239	-	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Ami_3
IGHMFEHH_00133	1.15e-238	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IGHMFEHH_00134	1.8e-216	-	-	-	M	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	POTRA domain, FtsQ-type
IGHMFEHH_00135	1.44e-228	ddl	6.3.2.4	-	M	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	D-ala D-ala ligase N-terminus
IGHMFEHH_00136	0.0	murB	-	-	M	-	-	-	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain
IGHMFEHH_00137	5.55e-267	-	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IGHMFEHH_00138	1.33e-277	-	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Cell cycle protein
IGHMFEHH_00139	1e-160	mltD	-	CBM50	M	ko:K08307,ko:K12204,ko:K19224	-	ko00000,ko01000,ko01002,ko01011,ko02044	LysM domain
IGHMFEHH_00140	1.19e-313	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IGHMFEHH_00141	1.99e-261	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IGHMFEHH_00142	0.0	-	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Mur ligase middle domain
IGHMFEHH_00143	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IGHMFEHH_00144	0.0	-	3.4.16.4	-	M	ko:K03587	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011,ko03036	Penicillin-binding Protein dimerisation domain
IGHMFEHH_00146	0.0	rsmH	2.1.1.199	-	M	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
IGHMFEHH_00147	4.54e-105	-	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
IGHMFEHH_00148	5.27e-189	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
IGHMFEHH_00149	2.82e-154	-	-	-	S	-	-	-	UPF0126 domain
IGHMFEHH_00150	7.18e-13	-	-	-	S	-	-	-	Mac 1
IGHMFEHH_00152	1.51e-174	-	-	-	K	-	-	-	Putative ATP-dependent DNA helicase recG C-terminal
IGHMFEHH_00154	5.37e-50	-	-	-	S	-	-	-	AAA domain
IGHMFEHH_00155	1.29e-96	-	-	-	V	-	-	-	HNH endonuclease
IGHMFEHH_00156	2.4e-236	-	2.1.1.72	-	L	ko:K07318	-	ko00000,ko01000,ko02048	D12 class N6 adenine-specific DNA methyltransferase
IGHMFEHH_00161	1.31e-56	-	-	-	U	-	-	-	Mobilization protein
IGHMFEHH_00162	3.17e-26	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
IGHMFEHH_00163	1.16e-100	-	-	-	L	-	-	-	MerR family transcriptional regulator
IGHMFEHH_00164	8.07e-314	mnmE	-	-	J	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IGHMFEHH_00165	2.72e-263	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
IGHMFEHH_00166	7.59e-206	miaA	2.5.1.75	-	J	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IGHMFEHH_00167	2.94e-184	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
IGHMFEHH_00168	1.04e-272	-	-	-	S	ko:K11941	-	ko00000,ko01000	transferase activity, transferring acyl groups other than amino-acyl groups
IGHMFEHH_00169	3.73e-144	-	-	-	S	-	-	-	Hexapeptide repeat of succinyl-transferase
IGHMFEHH_00170	4.02e-284	-	-	-	M	-	-	-	Glycosyl transferases group 1
IGHMFEHH_00171	2.61e-288	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
IGHMFEHH_00172	0.0	-	-	-	S	-	-	-	polysaccharide biosynthetic process
IGHMFEHH_00174	9.17e-243	-	-	-	H	-	-	-	PFAM glycosyl transferase family 8
IGHMFEHH_00175	1.68e-246	-	-	-	M	-	-	-	Glycosyl transferase, family 2
IGHMFEHH_00176	9.03e-256	MA20_42350	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	Glycosyl transferase, family 2
IGHMFEHH_00177	1.51e-281	-	1.8.1.2	-	P	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	FAD binding domain
IGHMFEHH_00178	9.5e-239	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IGHMFEHH_00179	3.4e-243	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
IGHMFEHH_00181	6.69e-204	-	-	-	J	-	-	-	Piwi
IGHMFEHH_00183	1.7e-13	-	-	-	K	-	-	-	Restriction-modification system regulatory protein
IGHMFEHH_00184	0.0	-	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	transmembrane transport
IGHMFEHH_00185	0.0	-	3.2.1.18	GH33	G	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	ko00000,ko00001,ko01000,ko02042	BNR/Asp-box repeat
IGHMFEHH_00186	3.99e-276	-	-	-	K	-	-	-	Periplasmic binding protein-like domain
IGHMFEHH_00187	0.0	-	3.2.1.18	GH33	G	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	ko00000,ko00001,ko01000,ko02042	exo-alpha-(2->6)-sialidase activity
IGHMFEHH_00189	2.28e-79	-	-	-	P	ko:K11741	-	ko00000,ko02000	Small Multidrug Resistance protein
IGHMFEHH_00190	0.0	-	6.3.5.1	-	H	ko:K01950	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	NAD synthase
IGHMFEHH_00191	1.98e-179	-	-	-	Q	-	-	-	methyltransferase activity
IGHMFEHH_00193	1.19e-137	-	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	Serine/threonine phosphatases, family 2C, catalytic domain
IGHMFEHH_00194	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase large chain, oligomerisation domain
IGHMFEHH_00195	5.29e-198	-	-	-	-	-	-	-	-
IGHMFEHH_00196	4.91e-121	-	3.2.2.28	-	L	ko:K03649	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	G/U mismatch-specific uracil-DNA glycosylase activity
IGHMFEHH_00197	3.12e-224	-	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III, delta subunit
IGHMFEHH_00198	4.98e-117	hisI	3.5.4.19	-	E	ko:K01496	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Phosphoribosyl-AMP cyclohydrolase
IGHMFEHH_00199	2.76e-169	-	-	-	S	ko:K05807	-	ko00000,ko02000	Outer membrane lipoprotein
IGHMFEHH_00200	7.51e-116	-	-	-	S	-	-	-	Lipopolysaccharide-assembly
IGHMFEHH_00201	4.63e-161	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Tetrapyrrole (Corrin/Porphyrin) Methylases
IGHMFEHH_00202	4.4e-180	-	-	-	S	-	-	-	Endonuclease/Exonuclease/phosphatase family
IGHMFEHH_00203	2.72e-18	-	-	-	-	-	-	-	-
IGHMFEHH_00204	0.0	-	-	-	P	ko:K07221	-	ko00000,ko02000	Phosphate-selective porin O and P
IGHMFEHH_00205	3.86e-162	rnc	3.1.26.3	-	K	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
IGHMFEHH_00206	1.78e-119	actI	1.5.1.36	-	S	ko:K00484	ko00350,ko00740,ko01100,ko01120,ko01220,map00350,map00740,map01100,map01120,map01220	ko00000,ko00001,ko01000	FMN binding
IGHMFEHH_00207	2.14e-257	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IGHMFEHH_00208	8.17e-147	-	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
IGHMFEHH_00209	1.14e-142	-	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Cytidylate kinase
IGHMFEHH_00210	0.0	-	-	-	I	-	-	-	Acetyltransferase (GNAT) domain
IGHMFEHH_00211	5.73e-208	thiL	2.7.4.16	-	H	ko:K00946	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IGHMFEHH_00212	4.34e-202	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
IGHMFEHH_00213	0.0	-	-	-	GK	-	-	-	carbohydrate kinase activity
IGHMFEHH_00214	0.0	-	-	-	KLT	-	-	-	Protein tyrosine kinase
IGHMFEHH_00216	4.41e-289	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IGHMFEHH_00217	2.02e-131	-	-	-	D	ko:K06287	-	ko00000	Maf-like protein
IGHMFEHH_00218	0.0	-	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
IGHMFEHH_00225	1.48e-84	-	-	-	T	-	-	-	pathogenesis
IGHMFEHH_00226	8.94e-135	-	-	-	F	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
IGHMFEHH_00227	3.4e-173	-	-	-	S	-	-	-	peptidoglycan biosynthetic process
IGHMFEHH_00228	3.06e-205	-	1.4.1.16	-	S	ko:K03340	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
IGHMFEHH_00230	0.000103	-	-	-	S	-	-	-	Entericidin EcnA/B family
IGHMFEHH_00231	1.15e-232	-	-	-	S	ko:K07192	ko04910,map04910	ko00000,ko00001,ko03036,ko04131,ko04147	prohibitin homologues
IGHMFEHH_00232	2.13e-118	-	-	-	-	-	-	-	-
IGHMFEHH_00233	0.0	-	-	-	S	ko:K07263	-	ko00000,ko01000,ko01002	Insulinase (Peptidase family M16)
IGHMFEHH_00234	3.71e-52	-	-	-	-	-	-	-	-
IGHMFEHH_00235	3.67e-297	lpxK	2.7.1.130	-	M	ko:K00912	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)
IGHMFEHH_00236	8.51e-128	-	-	-	S	ko:K07164	-	ko00000	C4-type zinc ribbon domain
IGHMFEHH_00237	2.24e-264	-	3.1.13.5	-	J	ko:K03684	-	ko00000,ko01000,ko03016	3'-5' exonuclease
IGHMFEHH_00238	3.68e-75	-	-	-	-	-	-	-	-
IGHMFEHH_00239	4.15e-191	-	3.6.1.66	-	S	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	MazG nucleotide pyrophosphohydrolase domain
IGHMFEHH_00240	2.92e-70	-	-	-	-	-	-	-	-
IGHMFEHH_00241	9.79e-180	-	-	-	S	-	-	-	competence protein
IGHMFEHH_00242	2.28e-98	-	-	-	S	ko:K07107	-	ko00000,ko01000	Thioesterase-like superfamily
IGHMFEHH_00246	0.0	-	3.1.6.1	-	P	ko:K01130	ko00140,ko00600,map00140,map00600	ko00000,ko00001,ko01000	Sulfatase
IGHMFEHH_00247	1.07e-142	-	-	-	-	-	-	-	-
IGHMFEHH_00248	9.08e-165	-	-	-	NU	-	-	-	Prokaryotic N-terminal methylation motif
IGHMFEHH_00249	1.96e-177	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IGHMFEHH_00250	1.11e-299	-	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	16S rRNA methyltransferase RsmB/F
IGHMFEHH_00251	1.26e-112	-	3.1.6.8	-	P	ko:K01134	ko00600,ko04142,map00600,map04142	ko00000,ko00001,ko01000	COG3119 Arylsulfatase A
IGHMFEHH_00252	2.9e-316	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Arginosuccinate synthase
IGHMFEHH_00254	2.79e-54	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IGHMFEHH_00255	8.43e-59	-	-	-	S	-	-	-	Zinc ribbon domain
IGHMFEHH_00256	4.77e-310	-	-	-	S	-	-	-	PFAM CBS domain containing protein
IGHMFEHH_00257	2.06e-150	-	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HII
IGHMFEHH_00258	2.8e-81	-	-	-	L	ko:K07460	-	ko00000	Uncharacterised protein family UPF0102
IGHMFEHH_00260	2.27e-175	-	4.1.1.48	-	E	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Indole-3-glycerol phosphate synthase
IGHMFEHH_00261	1.33e-226	-	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil DNA glycosylase superfamily
IGHMFEHH_00262	1.39e-157	-	-	-	S	-	-	-	3D domain
IGHMFEHH_00263	2.15e-151	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IGHMFEHH_00264	9.91e-171	-	-	-	U	ko:K03561	-	ko00000,ko02000	MotA/TolQ/ExbB proton channel family
IGHMFEHH_00265	3.19e-111	aglS	-	-	U	ko:K03559	-	ko00000,ko02000	biopolymer transport protein
IGHMFEHH_00266	5.28e-100	exbD2	-	-	U	ko:K03559	-	ko00000,ko02000	biopolymer transport protein
IGHMFEHH_00267	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
IGHMFEHH_00268	1.65e-188	-	-	-	-	-	-	-	-
IGHMFEHH_00269	2.58e-276	-	-	-	K	-	-	-	sequence-specific DNA binding
IGHMFEHH_00270	0.0	-	-	-	J	ko:K08301	-	ko00000,ko01000,ko03009,ko03019	Ribonuclease E/G family
IGHMFEHH_00271	5.06e-236	-	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Actin
IGHMFEHH_00272	0.0	lacZ_17	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase activity
IGHMFEHH_00274	1.84e-262	-	-	-	G	-	-	-	M42 glutamyl aminopeptidase
IGHMFEHH_00276	1.3e-177	-	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	CobB/CobQ-like glutamine amidotransferase domain
IGHMFEHH_00277	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate
IGHMFEHH_00278	6.74e-117	-	-	-	-	-	-	-	-
IGHMFEHH_00279	1.89e-166	-	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	SAICAR synthetase
IGHMFEHH_00280	0.0	-	-	-	K	-	-	-	Transcription elongation factor, N-terminal
IGHMFEHH_00281	0.0	-	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IGHMFEHH_00282	1.25e-179	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IGHMFEHH_00283	2.46e-307	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IGHMFEHH_00284	1.34e-201	-	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Serine acetyltransferase, N-terminal
IGHMFEHH_00285	1.06e-109	-	-	-	S	ko:K15977	-	ko00000	DoxX
IGHMFEHH_00286	9.25e-291	-	4.2.1.129, 5.4.99.17	-	I	ko:K06045	ko00909,ko01110,map00909,map01110	ko00000,ko00001,ko01000	PFAM Prenyltransferase squalene oxidase
IGHMFEHH_00287	4.7e-193	-	-	-	-	-	-	-	-
IGHMFEHH_00288	6.8e-224	-	5.3.1.13	-	M	ko:K06041	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	SIS domain
IGHMFEHH_00289	9.39e-183	-	-	-	H	-	-	-	ThiF family
IGHMFEHH_00290	3.67e-126	-	-	-	U	-	-	-	response to pH
IGHMFEHH_00291	2.38e-222	-	-	-	-	-	-	-	-
IGHMFEHH_00292	5.81e-218	-	-	-	I	-	-	-	alpha/beta hydrolase fold
IGHMFEHH_00294	4.75e-59	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
IGHMFEHH_00295	1.15e-70	-	-	-	S	-	-	-	Haem-degrading
IGHMFEHH_00297	0.0	-	-	-	G	-	-	-	Raffinose synthase or seed imbibition protein Sip1
IGHMFEHH_00298	2.1e-269	-	-	-	S	-	-	-	COGs COG4299 conserved
IGHMFEHH_00299	1.71e-151	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
IGHMFEHH_00300	0.0	-	3.4.16.4	-	M	ko:K05515	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein dimerisation domain
IGHMFEHH_00301	0.0	-	-	-	-	-	-	-	-
IGHMFEHH_00302	6.27e-219	-	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	ATP synthase A chain
IGHMFEHH_00303	1.65e-11	-	-	-	S	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	PFAM H transporting two-sector ATPase C subunit
IGHMFEHH_00304	4.38e-78	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	ATP synthase B/B' CF(0)
IGHMFEHH_00305	6.46e-86	-	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	ATP synthase delta (OSCP) subunit
IGHMFEHH_00306	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IGHMFEHH_00307	4.5e-201	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IGHMFEHH_00308	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IGHMFEHH_00309	1.24e-90	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
IGHMFEHH_00310	1.38e-139	-	-	-	-	-	-	-	-
IGHMFEHH_00311	3.93e-117	sprT	-	-	K	-	-	-	SprT-like family
IGHMFEHH_00312	3.71e-260	-	-	-	S	-	-	-	COGs COG4299 conserved
IGHMFEHH_00313	1.09e-284	-	2.6.1.59	-	M	ko:K02805	-	ko00000,ko01000,ko01007	DegT/DnrJ/EryC1/StrS aminotransferase family
IGHMFEHH_00314	2.96e-106	flmH	2.3.1.57	-	J	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	ko00000,ko00001,ko00002,ko01000	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IGHMFEHH_00315	1.21e-216	-	-	-	M	-	-	-	Glycosyl transferase family 2
IGHMFEHH_00316	2.19e-73	-	-	-	P	ko:K03297,ko:K11741	-	ko00000,ko02000	Multidrug Resistance protein
IGHMFEHH_00317	3.22e-72	-	-	-	P	ko:K03297,ko:K11741	-	ko00000,ko02000	Multidrug Resistance protein
IGHMFEHH_00320	0.0	-	2.6.1.62	-	H	ko:K00833	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
IGHMFEHH_00321	6.9e-232	-	2.8.1.6	-	H	ko:K01012	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Biotin and Thiamin Synthesis associated domain
IGHMFEHH_00322	0.0	-	-	-	P	-	-	-	Sulfatase
IGHMFEHH_00324	9.5e-283	-	-	-	O	ko:K09015	-	ko00000	Uncharacterized protein family (UPF0051)
IGHMFEHH_00325	0.0	-	-	-	O	ko:K09014	-	ko00000	Uncharacterized protein family (UPF0051)
IGHMFEHH_00326	1.75e-179	-	-	-	O	ko:K09013	-	ko00000,ko02000	ATPases associated with a variety of cellular activities
IGHMFEHH_00327	5.58e-99	-	-	-	P	ko:K09825	-	ko00000,ko03000	Ferric uptake regulator family
IGHMFEHH_00328	2.14e-57	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L27 protein
IGHMFEHH_00329	1.11e-65	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal prokaryotic L21 protein
IGHMFEHH_00330	3.9e-105	-	-	-	S	ko:K06925	-	ko00000,ko03016	Threonylcarbamoyl adenosine biosynthesis protein TsaE
IGHMFEHH_00331	6.65e-194	-	-	-	S	ko:K06889	-	ko00000	alpha beta
IGHMFEHH_00333	0.0	-	-	-	M	-	-	-	Parallel beta-helix repeats
IGHMFEHH_00334	0.0	-	-	-	-	-	-	-	-
IGHMFEHH_00335	2.58e-225	-	-	-	S	-	-	-	Polyphosphate kinase 2 (PPK2)
IGHMFEHH_00337	1.36e-175	-	-	-	-	-	-	-	-
IGHMFEHH_00338	3.35e-131	-	-	-	L	-	-	-	Conserved hypothetical protein 95
IGHMFEHH_00339	2.89e-310	-	2.4.99.12, 2.4.99.13, 2.4.99.14, 2.4.99.15	GT30	M	ko:K02527	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase)
IGHMFEHH_00340	1.1e-231	-	-	-	S	-	-	-	Aspartyl protease
IGHMFEHH_00341	9.65e-272	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
IGHMFEHH_00342	2.4e-160	-	6.3.2.5	-	H	ko:K21977	ko00770,map00770	ko00000,ko00001,ko00002,ko01000	DNA / pantothenate metabolism flavoprotein
IGHMFEHH_00343	1.61e-277	-	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class-V
IGHMFEHH_00344	3.35e-105	-	-	-	K	ko:K03826	-	ko00000,ko01000	acetyltransferase
IGHMFEHH_00345	2.48e-173	-	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
IGHMFEHH_00346	0.0	-	-	-	L	-	-	-	Polyphosphate kinase 2 (PPK2)
IGHMFEHH_00347	0.0	-	-	-	S	-	-	-	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
IGHMFEHH_00348	6.63e-259	-	-	-	M	-	-	-	Peptidase family M23
IGHMFEHH_00350	8.37e-126	-	4.1.1.36	-	H	ko:K01598	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Flavoprotein
IGHMFEHH_00351	1.31e-81	-	-	-	DJ	-	-	-	Addiction module toxin, RelE StbE family
IGHMFEHH_00352	6.71e-208	-	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
IGHMFEHH_00354	1.26e-139	-	-	-	K	ko:K03088	-	ko00000,ko03021	ECF sigma factor
IGHMFEHH_00355	0.0	-	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IGHMFEHH_00356	6.75e-245	-	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	AIR synthase related protein, N-terminal domain
IGHMFEHH_00357	1.84e-105	-	-	-	S	ko:K15977	-	ko00000	DoxX
IGHMFEHH_00358	1.35e-240	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
IGHMFEHH_00359	0.0	-	3.1.1.53	-	E	ko:K05970	-	ko00000,ko01000	Carbohydrate esterase, sialic acid-specific acetylesterase
IGHMFEHH_00360	3.41e-173	-	-	-	-	-	-	-	-
IGHMFEHH_00361	0.0	-	3.6.4.13	-	L	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DbpA RNA binding domain
IGHMFEHH_00362	0.0	-	-	-	P	ko:K01138	-	ko00000,ko01000	PA14 domain
IGHMFEHH_00363	2.16e-150	-	-	-	L	-	-	-	Membrane
IGHMFEHH_00365	0.0	gcvP	1.4.4.2	-	E	ko:K00281	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IGHMFEHH_00366	6.67e-86	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
IGHMFEHH_00367	2.85e-267	gcvT	2.1.2.10	-	E	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Aminomethyltransferase folate-binding domain
IGHMFEHH_00368	1.11e-261	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
IGHMFEHH_00369	4.25e-219	-	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
IGHMFEHH_00370	1.04e-267	-	-	-	LU	ko:K04096	-	ko00000	DNA recombination-mediator protein A
IGHMFEHH_00371	2.1e-269	-	-	-	M	-	-	-	Glycosyl transferase 4-like
IGHMFEHH_00372	4.82e-224	-	-	-	M	ko:K07276	-	ko00000	Mitochondrial fission ELM1
IGHMFEHH_00373	3.9e-270	-	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Domain of unknown function (DUF1730)
IGHMFEHH_00374	1.11e-79	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IGHMFEHH_00375	2.11e-121	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IGHMFEHH_00376	4.36e-142	-	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S4/S9 N-terminal domain
IGHMFEHH_00377	3.44e-192	-	-	-	E	-	-	-	haloacid dehalogenase-like hydrolase
IGHMFEHH_00381	1.78e-123	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
IGHMFEHH_00382	0.0	-	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Pyruvate kinase, barrel domain
IGHMFEHH_00383	5.92e-289	-	3.5.1.42	-	S	ko:K03742	ko00760,map00760	ko00000,ko00001,ko01000	Competence-damaged protein
IGHMFEHH_00384	9.75e-153	-	-	-	O	-	-	-	methyltransferase activity
IGHMFEHH_00385	7.92e-183	-	-	-	U	ko:K20276	ko02024,map02024	ko00000,ko00001	domain, Protein
IGHMFEHH_00386	0.0	-	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	DnaB-like helicase C terminal domain
IGHMFEHH_00387	2.62e-262	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Elongator protein 3, MiaB family, Radical SAM
IGHMFEHH_00388	2.23e-197	-	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	SRP54-type protein, GTPase domain
IGHMFEHH_00389	1.15e-205	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IGHMFEHH_00390	7.32e-105	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
IGHMFEHH_00391	1.59e-286	-	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase II
IGHMFEHH_00392	0.0	glnS	6.1.1.18	-	J	ko:K01886	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class I (E and Q), anti-codon binding domain
IGHMFEHH_00393	0.0	-	-	-	-	-	-	-	-
IGHMFEHH_00394	0.0	-	-	-	EGP	-	-	-	Sugar (and other) transporter
IGHMFEHH_00395	3.42e-259	-	-	-	S	-	-	-	ankyrin repeats
IGHMFEHH_00396	6.33e-313	hemL	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
IGHMFEHH_00397	1.06e-44	-	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S21
IGHMFEHH_00398	0.0	-	2.7.1.167, 2.7.7.70	-	M	ko:K03272	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	pfkB family carbohydrate kinase
IGHMFEHH_00399	5.57e-129	-	5.3.1.28	-	G	ko:K03271	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	SIS domain
IGHMFEHH_00400	6.23e-118	-	3.1.3.82, 3.1.3.83	-	E	ko:K03273	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Polynucleotide kinase 3 phosphatase
IGHMFEHH_00401	1.41e-221	hyl	2.3.1.48, 3.2.1.169, 3.2.1.35	GH84	G	ko:K01197,ko:K15719	ko00531,ko01100,ko04931,map00531,map01100,map04931	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	beta-N-acetylhexosaminidase activity
IGHMFEHH_00403	7.38e-252	-	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	NMT1/THI5 like
IGHMFEHH_00404	5.69e-190	-	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IGHMFEHH_00405	1.2e-196	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IGHMFEHH_00406	5.68e-188	lpxD	2.3.1.191	-	M	ko:K02536	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IGHMFEHH_00407	1.48e-120	-	-	-	M	ko:K06142	-	ko00000	Outer membrane protein (OmpH-like)
IGHMFEHH_00408	3.42e-196	panC	6.3.2.1	-	H	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
IGHMFEHH_00409	1.83e-150	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IGHMFEHH_00410	6.25e-144	-	-	-	-	-	-	-	-
IGHMFEHH_00411	4.86e-201	-	-	-	S	-	-	-	DisA bacterial checkpoint controller nucleotide-binding
IGHMFEHH_00413	6.94e-153	-	6.3.3.3	-	H	ko:K01935	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	AAA domain
IGHMFEHH_00414	0.0	-	-	-	G	-	-	-	beta-N-acetylhexosaminidase activity
IGHMFEHH_00415	0.0	-	-	-	S	-	-	-	Type I phosphodiesterase / nucleotide pyrophosphatase
IGHMFEHH_00416	7.34e-181	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IGHMFEHH_00418	1.33e-174	-	-	-	NU	-	-	-	Prepilin-type N-terminal cleavage methylation domain
IGHMFEHH_00420	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	PFAM coagulation factor 5 8 type domain protein
IGHMFEHH_00421	9.86e-168	-	-	-	M	-	-	-	Peptidase family M23
IGHMFEHH_00422	1.04e-144	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IGHMFEHH_00423	7.54e-201	-	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
IGHMFEHH_00426	0.0	-	-	-	S	-	-	-	Terminase
IGHMFEHH_00427	2.36e-213	-	-	-	D	ko:K19234,ko:K19236	ko01503,map01503	ko00000,ko00001,ko01002,ko01011	ErfK ybiS ycfS ynhG family protein
IGHMFEHH_00428	2.71e-150	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
IGHMFEHH_00429	3.01e-49	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal_S15
IGHMFEHH_00430	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
IGHMFEHH_00431	9.05e-313	tlyC	-	-	S	ko:K03699	-	ko00000,ko02042	PFAM CBS domain containing protein
IGHMFEHH_00432	8e-310	-	-	-	S	-	-	-	PFAM CBS domain containing protein
IGHMFEHH_00433	0.0	-	-	-	C	-	-	-	Cytochrome c554 and c-prime
IGHMFEHH_00434	6.62e-164	-	-	-	CO	-	-	-	Thioredoxin-like
IGHMFEHH_00435	1.1e-159	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IGHMFEHH_00436	1.11e-154	-	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Thiamine monophosphate synthase
IGHMFEHH_00437	4.25e-238	pyrD	1.3.5.2	-	F	ko:K00254	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Dihydroorotate dehydrogenase
IGHMFEHH_00438	0.0	-	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase alpha chain like domain
IGHMFEHH_00439	5.21e-142	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
IGHMFEHH_00440	0.0	-	4.1.1.15	-	E	ko:K01580	ko00250,ko00410,ko00430,ko00650,ko01100,ko01110,ko01120,ko02024,ko04727,ko04940,map00250,map00410,map00430,map00650,map01100,map01110,map01120,map02024,map04727,map04940	ko00000,ko00001,ko00002,ko01000	Pyridoxal-dependent decarboxylase conserved domain
IGHMFEHH_00441	0.0	-	-	-	-	-	-	-	-
IGHMFEHH_00443	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	PFAM Glycoside hydrolase, family 20, catalytic core
IGHMFEHH_00445	0.0	-	-	-	P	ko:K03281	-	ko00000	Voltage gated chloride channel
IGHMFEHH_00446	0.0	-	-	-	KT	ko:K02584	ko02020,map02020	ko00000,ko00001,ko03000	Bacterial regulatory protein, Fis family
IGHMFEHH_00447	9.68e-221	-	2.5.1.21	-	I	ko:K00801	ko00100,ko00909,ko01100,ko01110,ko01130,map00100,map00909,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko01006	Squalene/phytoene synthase
IGHMFEHH_00448	0.0	-	-	-	S	-	-	-	Fungal chitosanase of glycosyl hydrolase group 75
IGHMFEHH_00449	4.65e-194	-	-	-	S	ko:K07124	-	ko00000	Enoyl-(Acyl carrier protein) reductase
IGHMFEHH_00450	8.38e-98	-	-	-	-	-	-	-	-
IGHMFEHH_00451	0.0	-	-	-	V	-	-	-	ABC-2 type transporter
IGHMFEHH_00454	3.43e-147	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
IGHMFEHH_00458	6.47e-303	-	-	-	MU	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	efflux transmembrane transporter activity
IGHMFEHH_00461	4.36e-200	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Enoyl-CoA hydratase/isomerase
IGHMFEHH_00462	1.29e-257	-	-	-	S	-	-	-	AAA domain, putative AbiEii toxin, Type IV TA system
IGHMFEHH_00464	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IGHMFEHH_00465	4.69e-79	rsfS	-	-	S	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
IGHMFEHH_00466	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IGHMFEHH_00467	1.59e-141	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Exonuclease
IGHMFEHH_00468	5.23e-172	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
IGHMFEHH_00469	0.0	-	-	-	CO	-	-	-	Disulphide bond corrector protein DsbC
IGHMFEHH_00470	1.86e-94	-	-	-	O	-	-	-	OsmC-like protein
IGHMFEHH_00472	3.42e-111	-	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	Cytidine and deoxycytidylate deaminase zinc-binding region
IGHMFEHH_00473	0.0	-	-	-	EGIP	-	-	-	Phosphate acyltransferases
IGHMFEHH_00475	1.02e-204	-	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydrogenase
IGHMFEHH_00476	0.0	-	-	-	P	ko:K02014	-	ko00000,ko02000	TonB dependent receptor
IGHMFEHH_00477	2.36e-166	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IGHMFEHH_00478	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
IGHMFEHH_00480	7.54e-156	cat	2.3.1.28	-	V	ko:K19271	-	br01600,ko00000,ko01000,ko01504	Chloramphenicol acetyltransferase
IGHMFEHH_00482	1.18e-228	-	-	-	EP	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
IGHMFEHH_00483	0.0	der	-	-	S	ko:K03977	-	ko00000,ko03009	KH-domain-like of EngA bacterial GTPase enzymes, C-terminal
IGHMFEHH_00484	9.67e-251	-	-	-	S	ko:K07091	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Predicted permease YjgP/YjgQ family
IGHMFEHH_00485	2.31e-127	-	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Recombination protein O N terminal
IGHMFEHH_00486	1.62e-182	-	-	-	S	-	-	-	Tetratricopeptide repeat
IGHMFEHH_00487	0.0	dxs	2.2.1.7	-	HI	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IGHMFEHH_00488	5.12e-51	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease VII activity
IGHMFEHH_00489	0.0	-	-	-	O	-	-	-	C-terminal four TMM region of protein-O-mannosyltransferase
IGHMFEHH_00490	0.0	-	-	-	T	-	-	-	Bacterial regulatory protein, Fis family
IGHMFEHH_00491	1.82e-274	-	-	-	T	-	-	-	PAS domain
IGHMFEHH_00492	3.37e-97	-	-	-	S	ko:K07107	-	ko00000,ko01000	Thioesterase superfamily
IGHMFEHH_00493	0.0	gpmI	5.4.2.12	-	G	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	BPG-independent PGAM N-terminus (iPGM_N)
IGHMFEHH_00494	4.16e-85	-	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S12/S23
IGHMFEHH_00495	2.91e-104	-	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S7p/S5e
IGHMFEHH_00496	0.0	-	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IGHMFEHH_00497	3.67e-65	-	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S10p/S20e
IGHMFEHH_00498	3.86e-149	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IGHMFEHH_00499	9.43e-132	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L4/L1 family
IGHMFEHH_00500	8.72e-58	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
IGHMFEHH_00501	1.85e-203	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IGHMFEHH_00502	1.05e-58	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IGHMFEHH_00503	4.05e-152	-	-	-	-	-	-	-	-
IGHMFEHH_00504	4.97e-70	-	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome
IGHMFEHH_00505	4.27e-155	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IGHMFEHH_00506	3.42e-97	-	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IGHMFEHH_00507	5.78e-35	-	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L29 protein
IGHMFEHH_00508	2.19e-56	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IGHMFEHH_00509	6.79e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IGHMFEHH_00510	3.74e-204	-	-	-	-	-	-	-	-
IGHMFEHH_00511	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
IGHMFEHH_00512	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Domain of unknown function (DUF4982)
IGHMFEHH_00513	2.73e-263	-	5.2.1.8	-	O	ko:K03771	-	ko00000,ko01000,ko03110	SurA N-terminal domain
IGHMFEHH_00514	3.02e-170	-	2.5.1.39	-	H	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
IGHMFEHH_00515	1.43e-142	-	-	-	U	ko:K03561	-	ko00000,ko02000	MotA/TolQ/ExbB proton channel family
IGHMFEHH_00521	1.9e-62	-	-	-	L	-	-	-	bacterial (prokaryotic) histone like domain
IGHMFEHH_00522	1.91e-204	-	3.1.26.4	-	L	ko:K03471	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HII
IGHMFEHH_00523	5.96e-127	-	-	-	M	ko:K03642	-	ko00000	Lytic transglycolase
IGHMFEHH_00524	3.55e-173	-	-	-	F	-	-	-	NUDIX domain
IGHMFEHH_00525	1.22e-150	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Putative methyltransferase
IGHMFEHH_00526	1.39e-282	tgt	2.4.2.29	-	J	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
IGHMFEHH_00527	5.64e-66	-	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit
IGHMFEHH_00528	1.08e-184	-	-	-	DTZ	-	-	-	EF-hand, calcium binding motif
IGHMFEHH_00529	1.31e-214	-	-	-	L	ko:K03733	-	ko00000,ko03036	Phage integrase, N-terminal SAM-like domain
IGHMFEHH_00530	1.03e-14	-	-	-	E	-	-	-	LysE type translocator
IGHMFEHH_00532	9.56e-51	-	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Ribosomal protein S16
IGHMFEHH_00533	1.55e-128	aroK	2.7.1.71	-	E	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IGHMFEHH_00534	6.97e-241	-	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
IGHMFEHH_00535	2.84e-79	-	-	-	FG	ko:K02503	-	ko00000,ko04147	HIT domain
IGHMFEHH_00536	4.98e-117	-	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
IGHMFEHH_00537	2.73e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
IGHMFEHH_00538	1.22e-246	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
IGHMFEHH_00539	0.0	-	-	-	S	ko:K07037	-	ko00000	7TM receptor with intracellular HD hydrolase
IGHMFEHH_00540	3.92e-115	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IGHMFEHH_00545	0.0	-	-	-	CO	-	-	-	Thioredoxin-like
IGHMFEHH_00547	3.34e-214	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IGHMFEHH_00548	2.73e-284	-	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	S-adenosylmethionine-dependent methyltransferase
IGHMFEHH_00549	2.72e-56	-	-	-	S	ko:K06960	-	ko00000	KH domain
IGHMFEHH_00550	0.0	-	-	-	-	-	-	-	-
IGHMFEHH_00551	0.0	-	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	RNA cap guanine-N2 methyltransferase
IGHMFEHH_00552	8.77e-216	-	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
IGHMFEHH_00553	1.92e-240	-	4.2.1.113	-	M	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Mandelate Racemase Muconate Lactonizing
IGHMFEHH_00554	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 20, domain 2
IGHMFEHH_00556	0.0	-	-	-	V	-	-	-	Polysaccharide biosynthesis C-terminal domain
IGHMFEHH_00557	0.0	-	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
IGHMFEHH_00558	3.33e-102	-	-	-	G	-	-	-	single-species biofilm formation
IGHMFEHH_00559	7.97e-113	-	-	-	K	ko:K13640	-	ko00000,ko03000	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
IGHMFEHH_00560	4.8e-128	-	-	-	S	-	-	-	Flavodoxin-like fold
IGHMFEHH_00561	2.61e-187	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Cupin domain
IGHMFEHH_00562	3.29e-99	-	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
IGHMFEHH_00563	9.98e-129	-	-	-	C	-	-	-	FMN binding
IGHMFEHH_00564	2.96e-264	-	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase
IGHMFEHH_00565	7.33e-271	-	-	-	C	-	-	-	Aldo/keto reductase family
IGHMFEHH_00566	6.7e-265	-	-	-	S	ko:K06889	-	ko00000	X-Pro dipeptidyl-peptidase (S15 family)
IGHMFEHH_00567	1.12e-206	-	-	-	S	-	-	-	Aldo/keto reductase family
IGHMFEHH_00568	6.96e-239	-	1.2.7.3	-	-	ko:K00176,ko:K07138	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	br01601,ko00000,ko00001,ko00002,ko01000	-
IGHMFEHH_00569	2.31e-300	-	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase class I and II
IGHMFEHH_00570	3.25e-141	-	-	-	M	-	-	-	polygalacturonase activity
IGHMFEHH_00572	2.71e-191	-	-	-	KT	-	-	-	Peptidase S24-like
IGHMFEHH_00573	1.36e-288	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
IGHMFEHH_00576	6.57e-176	-	-	-	O	-	-	-	Trypsin
IGHMFEHH_00577	4.04e-240	-	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
IGHMFEHH_00578	1.03e-201	-	-	-	-	-	-	-	-
IGHMFEHH_00579	0.0	-	-	-	S	-	-	-	Sulfatase-modifying factor enzyme 1
IGHMFEHH_00580	4.53e-283	-	-	-	S	-	-	-	Tetratricopeptide repeat
IGHMFEHH_00582	2.63e-10	-	-	-	-	-	-	-	-
IGHMFEHH_00584	8.23e-62	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IGHMFEHH_00585	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
IGHMFEHH_00586	2.48e-228	-	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
IGHMFEHH_00587	4.38e-211	-	-	-	S	-	-	-	Protein of unknown function DUF58
IGHMFEHH_00588	1.98e-134	-	-	-	-	-	-	-	-
IGHMFEHH_00589	1.33e-228	-	-	-	S	-	-	-	Protein of unknown function (DUF1194)
IGHMFEHH_00591	6.21e-39	-	-	-	-	-	-	-	-
IGHMFEHH_00592	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
IGHMFEHH_00594	9.83e-235	-	-	-	CO	-	-	-	Thioredoxin-like
IGHMFEHH_00595	0.0	-	-	-	P	-	-	-	Domain of unknown function (DUF4976)
IGHMFEHH_00596	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycoside hydrolase, family 20, catalytic core
IGHMFEHH_00597	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class I (C) catalytic domain
IGHMFEHH_00598	1.37e-76	-	-	-	G	-	-	-	Cupin 2, conserved barrel domain protein
IGHMFEHH_00599	5.74e-211	ybfH	-	-	EG	-	-	-	spore germination
IGHMFEHH_00600	9.28e-139	-	-	-	-	-	-	-	-
IGHMFEHH_00601	0.0	-	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
IGHMFEHH_00602	3.62e-121	-	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IGHMFEHH_00603	5.26e-188	-	-	-	O	ko:K04083	-	ko00000,ko03110	Hsp33 protein
IGHMFEHH_00606	3.71e-236	-	-	-	E	-	-	-	PFAM lipolytic protein G-D-S-L family
IGHMFEHH_00608	4.12e-272	-	-	-	I	-	-	-	Prenyltransferase and squalene oxidase repeat
IGHMFEHH_00609	6.39e-119	-	-	-	T	-	-	-	STAS domain
IGHMFEHH_00610	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF2851)
IGHMFEHH_00611	0.0	-	3.2.1.51	GH95	G	ko:K15923	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65, N-terminal domain
IGHMFEHH_00612	1.86e-291	-	-	-	-	-	-	-	-
IGHMFEHH_00613	0.0	-	-	-	M	-	-	-	Sulfatase
IGHMFEHH_00614	2.33e-286	-	4.1.99.19	-	H	ko:K03150	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Biotin and Thiamin Synthesis associated domain
IGHMFEHH_00615	1.39e-206	-	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil DNA glycosylase superfamily
IGHMFEHH_00616	8.14e-268	xerD1	-	-	L	ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
IGHMFEHH_00617	0.0	-	-	-	T	-	-	-	pathogenesis
IGHMFEHH_00618	0.0	-	4.2.1.9	-	EG	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Dehydratase family
IGHMFEHH_00619	2.81e-167	-	-	-	T	ko:K07657	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
IGHMFEHH_00620	7.06e-290	-	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
IGHMFEHH_00621	2.09e-10	-	-	-	S	-	-	-	Mitochondrial domain of unknown function (DUF1713)
IGHMFEHH_00622	3.88e-207	hisG	2.4.2.17	-	E	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	ATP phosphoribosyltransferase
IGHMFEHH_00623	5.87e-314	-	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	Aminopeptidase P, N-terminal domain
IGHMFEHH_00624	1.4e-155	-	-	-	S	-	-	-	Protein of unknown function (DUF3313)
IGHMFEHH_00625	2.15e-262	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IGHMFEHH_00626	3.99e-257	-	-	-	G	-	-	-	M42 glutamyl aminopeptidase
IGHMFEHH_00627	2.8e-169	-	-	-	-	-	-	-	-
IGHMFEHH_00628	0.0	-	-	-	NU	-	-	-	Type IV pilus assembly protein PilM;
IGHMFEHH_00629	6.11e-208	-	-	-	-	-	-	-	-
IGHMFEHH_00630	3.22e-245	-	-	-	-	-	-	-	-
IGHMFEHH_00631	0.0	-	-	-	NU	ko:K02453	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02044	Bacterial type II and III secretion system protein
IGHMFEHH_00632	1.85e-142	coaE	2.7.1.24	-	H	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IGHMFEHH_00633	0.0	-	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IGHMFEHH_00634	0.0	-	-	-	P	-	-	-	E1-E2 ATPase
IGHMFEHH_00635	3.46e-242	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
IGHMFEHH_00636	1.1e-131	tadA	3.5.4.33	-	FJ	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
IGHMFEHH_00637	1.56e-228	lipA	2.8.1.8	-	H	ko:K03644	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IGHMFEHH_00638	0.0	-	1.11.1.5	-	P	ko:K00428	-	ko00000,ko01000	Di-haem cytochrome c peroxidase
IGHMFEHH_00639	2.48e-40	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	iron ion homeostasis
IGHMFEHH_00640	4.02e-48	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	iron ion homeostasis
IGHMFEHH_00641	0.0	-	-	-	P	ko:K04759	-	ko00000,ko02000	Ferrous iron transport protein B C terminus
IGHMFEHH_00644	2.83e-303	-	-	-	M	ko:K07267	-	ko00000,ko02000	wide pore channel activity
IGHMFEHH_00646	0.0	-	-	-	P	-	-	-	E1-E2 ATPase
IGHMFEHH_00647	9.94e-90	-	-	-	K	-	-	-	Helix-turn-helix diphteria tox regulatory element
IGHMFEHH_00648	2.64e-205	-	3.1.1.53	-	L	ko:K03547,ko:K05970	-	ko00000,ko01000,ko03400	3'-5' exonuclease activity
IGHMFEHH_00649	2.86e-133	-	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	SpoU rRNA Methylase family
IGHMFEHH_00650	0.0	-	1.4.3.16	-	H	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Fumarate reductase flavoprotein C-term
IGHMFEHH_00651	3.98e-257	-	-	-	S	-	-	-	Glycoside-hydrolase family GH114
IGHMFEHH_00652	3.86e-304	-	-	-	M	-	-	-	Glycosyl transferases group 1
IGHMFEHH_00654	0.0	-	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	RecQ zinc-binding
IGHMFEHH_00655	0.0	-	-	-	P	-	-	-	Domain of unknown function (DUF4976)
IGHMFEHH_00656	8.66e-227	-	-	-	-	-	-	-	-
IGHMFEHH_00657	0.0	-	-	-	H	-	-	-	Flavin containing amine oxidoreductase
IGHMFEHH_00658	7.61e-248	-	-	-	-	-	-	-	-
IGHMFEHH_00659	3.5e-249	rgpB	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
IGHMFEHH_00660	0.0	ahcY	3.3.1.1	-	H	ko:K01251	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
IGHMFEHH_00661	3.77e-291	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IGHMFEHH_00662	3.9e-214	-	-	-	KQ	-	-	-	Hypothetical methyltransferase
IGHMFEHH_00665	0.0	-	-	-	E	-	-	-	PFAM major facilitator superfamily MFS_1
IGHMFEHH_00666	1.83e-205	-	-	-	G	ko:K06867,ko:K07001	-	ko00000	response to abiotic stimulus
IGHMFEHH_00668	7.13e-294	-	-	-	MU	ko:K15725	-	ko00000,ko02000	efflux transmembrane transporter activity
IGHMFEHH_00669	3.95e-297	czcB	-	-	M	ko:K15727	-	ko00000,ko02000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IGHMFEHH_00670	0.0	-	-	-	P	ko:K07239	-	ko00000	AcrB/AcrD/AcrF family
IGHMFEHH_00671	8.45e-147	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IGHMFEHH_00673	3.95e-168	-	-	-	CO	-	-	-	Protein conserved in bacteria
IGHMFEHH_00674	2.6e-231	-	1.5.1.20	-	E	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Methylenetetrahydrofolate reductase
IGHMFEHH_00675	5.9e-156	-	1.14.11.27	-	P	ko:K10277	-	ko00000,ko01000,ko03036	peptidyl-arginine hydroxylation
IGHMFEHH_00676	0.0	-	-	-	M	ko:K07277	-	ko00000,ko02000,ko03029	Surface antigen
IGHMFEHH_00677	8.38e-282	tig	-	-	O	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
IGHMFEHH_00678	2.5e-153	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
IGHMFEHH_00679	0.0	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IGHMFEHH_00680	2.49e-256	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IGHMFEHH_00682	9.94e-287	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IGHMFEHH_00684	3.61e-46	-	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	SecE/Sec61-gamma subunits of protein translocation complex
IGHMFEHH_00685	6.29e-135	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	In Spt5p, this domain may confer affinity for Spt4p. It possesses a RNP-like fold.
IGHMFEHH_00686	1.05e-92	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IGHMFEHH_00687	4.97e-156	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
IGHMFEHH_00688	9.92e-110	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IGHMFEHH_00689	3.69e-64	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
IGHMFEHH_00691	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IGHMFEHH_00693	1.25e-204	dapA	4.3.3.7	-	EM	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Dihydrodipicolinate synthetase family
IGHMFEHH_00694	4.14e-175	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Dihydrodipicolinate reductase, N-terminus
IGHMFEHH_00695	4.21e-121	-	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
IGHMFEHH_00696	4.13e-183	panB	2.1.2.11	-	H	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
IGHMFEHH_00697	1.96e-226	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
IGHMFEHH_00698	2.18e-210	-	-	-	M	-	-	-	Peptidase family M23
IGHMFEHH_00703	1.75e-110	-	-	-	S	-	-	-	Acetyltransferase (GNAT) family
IGHMFEHH_00704	1.21e-134	-	-	-	C	-	-	-	Nitroreductase family
IGHMFEHH_00705	0.0	-	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence
IGHMFEHH_00706	1.66e-87	-	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
IGHMFEHH_00707	8.8e-239	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IGHMFEHH_00708	6.63e-173	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	tRNA (Guanine-1)-methyltransferase
IGHMFEHH_00709	2.05e-28	-	-	-	-	-	-	-	-
IGHMFEHH_00710	2.55e-243	-	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	RNA pseudouridylate synthase
IGHMFEHH_00711	1.44e-238	-	-	-	S	-	-	-	PFAM Sel1 domain protein repeat-containing protein
IGHMFEHH_00712	1.16e-53	tatA	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
IGHMFEHH_00714	0.0	-	-	-	J	ko:K07576	-	ko00000	Beta-Casp domain
IGHMFEHH_00715	1.81e-82	-	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	ArsC family
IGHMFEHH_00716	4.82e-179	-	-	-	P	ko:K10716	-	ko00000,ko02000	domain protein
IGHMFEHH_00717	0.0	-	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Carbohydrate phosphorylase
IGHMFEHH_00718	2.04e-258	tdh	1.1.1.103	-	E	ko:K00060	ko00260,map00260	ko00000,ko00001,ko01000	Alcohol dehydrogenase GroES-like domain
IGHMFEHH_00719	5.46e-161	-	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IGHMFEHH_00721	6.34e-182	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
IGHMFEHH_00722	3.92e-115	-	-	-	-	-	-	-	-
IGHMFEHH_00726	0.0	-	-	-	L	-	-	-	DNA restriction-modification system
IGHMFEHH_00729	4.39e-165	-	-	-	S	-	-	-	PFAM Sel1 domain protein repeat-containing protein
IGHMFEHH_00731	1.74e-177	-	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
IGHMFEHH_00733	0.0	-	-	-	P	ko:K14445	-	ko00000,ko02000	Citrate transporter
IGHMFEHH_00734	0.0	-	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IGHMFEHH_00735	9.21e-286	mtrC	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IGHMFEHH_00736	0.0	-	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
IGHMFEHH_00738	0.0	-	-	-	G	-	-	-	alpha-galactosidase
IGHMFEHH_00740	0.0	poxB	1.2.3.3, 1.2.5.1	-	EH	ko:K00156,ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Thiamine pyrophosphate enzyme, central domain
IGHMFEHH_00741	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IGHMFEHH_00742	1.06e-180	-	-	-	L	ko:K10800	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	uracil-dna glycosylase
IGHMFEHH_00743	1.13e-228	-	2.7.1.11	-	G	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Phosphofructokinase
IGHMFEHH_00744	4.37e-270	-	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Male sterility protein
IGHMFEHH_00745	9.53e-206	-	2.7.7.24	-	M	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IGHMFEHH_00747	0.0	-	-	-	C	-	-	-	Acetyl-CoA hydrolase/transferase C-terminal domain
IGHMFEHH_00748	5.49e-191	-	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Biotin/lipoate A/B protein ligase family
IGHMFEHH_00749	0.0	-	4.1.1.3	-	C	ko:K01572	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	Na+-transporting oxaloacetate decarboxylase beta subunit
IGHMFEHH_00750	1.32e-52	-	-	-	I	-	-	-	PFAM biotin lipoyl attachment domain-containing protein
IGHMFEHH_00752	0.0	-	2.1.3.15, 6.4.1.3	-	I	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Carboxyl transferase domain
IGHMFEHH_00753	4.12e-100	-	5.1.99.1	-	E	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Glyoxalase-like domain
IGHMFEHH_00754	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
IGHMFEHH_00755	8.14e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
IGHMFEHH_00757	7.62e-05	-	2.7.11.1, 2.7.11.17	-	T	ko:K08794,ko:K13412,ko:K17530	ko04626,ko04921,ko04925,ko05145,map04626,map04921,map04925,map05145	ko00000,ko00001,ko01000,ko01001	protein serine/threonine kinase activity
IGHMFEHH_00759	0.0	-	-	-	S	-	-	-	acetyltransferases and hydrolases with the alpha beta hydrolase fold
IGHMFEHH_00760	2.22e-297	-	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IGHMFEHH_00761	3.13e-114	-	-	-	P	-	-	-	Rhodanese-like domain
IGHMFEHH_00762	3.27e-150	-	-	-	S	-	-	-	Protein of unknown function (DUF1573)
IGHMFEHH_00763	1.76e-186	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	Signal peptidase (SPase) II
IGHMFEHH_00764	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IGHMFEHH_00765	3.08e-243	-	-	-	I	-	-	-	alpha/beta hydrolase fold
IGHMFEHH_00766	2.3e-260	-	-	-	S	-	-	-	Peptidase family M28
IGHMFEHH_00767	0.0	-	3.2.1.51	GH95	G	ko:K15923	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65, N-terminal domain
IGHMFEHH_00768	5.62e-57	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
IGHMFEHH_00769	2.64e-89	-	-	-	S	ko:K09793	-	ko00000	Protein of unknown function (DUF456)
IGHMFEHH_00770	1.38e-209	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
IGHMFEHH_00771	0.0	-	-	-	M	ko:K09808	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	MacB-like periplasmic core domain
IGHMFEHH_00772	7.56e-208	-	-	-	S	-	-	-	RDD family
IGHMFEHH_00773	1.25e-132	-	2.3.1.129	-	M	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	ko00000,ko00001,ko00002,ko01000,ko01005	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IGHMFEHH_00774	1.4e-171	-	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD-hyrolase-like
IGHMFEHH_00775	1.21e-285	-	-	-	S	ko:K09760	-	ko00000	RmuC family
IGHMFEHH_00776	0.0	-	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Transglycosylase
IGHMFEHH_00777	9.19e-229	-	-	-	O	-	-	-	Trypsin-like peptidase domain
IGHMFEHH_00778	5.88e-277	-	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
IGHMFEHH_00782	3.28e-134	panZ	-	-	K	-	-	-	-acetyltransferase
IGHMFEHH_00783	3.3e-216	-	1.8.1.9	-	O	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Pyridine nucleotide-disulphide oxidoreductase
IGHMFEHH_00784	0.0	-	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase alpha chain
IGHMFEHH_00785	5.5e-176	-	-	-	-	-	-	-	-
IGHMFEHH_00787	9.55e-242	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IGHMFEHH_00788	3.2e-209	-	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Polyprenyl synthetase
IGHMFEHH_00789	3.42e-199	-	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Quinolinate phosphoribosyl transferase, N-terminal domain
IGHMFEHH_00790	3.45e-157	-	1.4.3.5	-	H	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)
IGHMFEHH_00791	3.77e-215	-	5.1.3.15	-	G	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Aldose 1-epimerase
IGHMFEHH_00792	0.0	-	-	-	G	-	-	-	Trehalase
IGHMFEHH_00793	0.0	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
IGHMFEHH_00794	0.0	glnA	6.3.1.2	-	S	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
IGHMFEHH_00795	1.1e-34	-	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L34
IGHMFEHH_00796	4.9e-76	-	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	Ribonuclease P
IGHMFEHH_00797	4.61e-61	-	-	-	S	ko:K08998	-	ko00000	Haemolytic
IGHMFEHH_00798	0.0	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins
IGHMFEHH_00799	0.0	-	1.4.1.13, 1.4.1.14	-	E	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	GXGXG motif
IGHMFEHH_00800	0.0	glnA	6.3.1.2	-	S	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
IGHMFEHH_00801	0.0	-	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase large chain, oligomerisation domain
IGHMFEHH_00802	1.88e-273	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase small chain, CPSase domain
IGHMFEHH_00804	6.96e-265	-	4.2.1.47	-	M	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
IGHMFEHH_00805	3.91e-270	fcl	1.1.1.271	-	GM	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction
IGHMFEHH_00806	4.33e-298	-	-	-	C	-	-	-	Na+/H+ antiporter family
IGHMFEHH_00807	2.9e-276	-	-	-	-	-	-	-	-
IGHMFEHH_00808	2.4e-229	-	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphomannose isomerase type I
IGHMFEHH_00809	7.49e-181	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	PFAM N-acetylmuramoyl-L-alanine amidase family 2
IGHMFEHH_00810	3.2e-116	ispF	4.6.1.12	-	I	ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
IGHMFEHH_00811	4.01e-186	-	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase family
IGHMFEHH_00812	0.0	-	-	-	M	-	-	-	PFAM glycosyl transferase family 51
IGHMFEHH_00813	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
IGHMFEHH_00814	1.08e-97	-	-	-	U	ko:K03559	-	ko00000,ko02000	Biopolymer transport protein ExbD/TolR
IGHMFEHH_00815	1.49e-181	-	-	-	U	ko:K03561	-	ko00000,ko02000	MotA/TolQ/ExbB proton channel family
IGHMFEHH_00816	0.0	-	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
IGHMFEHH_00817	1.27e-99	-	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Predicted SPOUT methyltransferase
IGHMFEHH_00818	1.67e-86	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S9/S16
IGHMFEHH_00819	2.79e-97	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IGHMFEHH_00820	1.07e-30	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IGHMFEHH_00821	0.0	nnrD	4.2.1.136, 5.1.99.6	-	G	ko:K17758,ko:K17759	-	ko00000,ko01000	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IGHMFEHH_00822	3.97e-173	-	-	-	L	ko:K03630	-	ko00000	RadC-like JAB domain
IGHMFEHH_00824	4.03e-174	-	-	-	D	-	-	-	Phage-related minor tail protein
IGHMFEHH_00826	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IGHMFEHH_00827	8.25e-63	-	-	-	L	ko:K09747	-	ko00000	YbaB/EbfC DNA-binding family
IGHMFEHH_00828	3.26e-254	-	-	-	N	ko:K18353	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01504	Endonuclease Exonuclease Phosphatase
IGHMFEHH_00829	0.0	-	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	DHHA2
IGHMFEHH_00831	5.46e-189	-	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Orotidine 5'-phosphate decarboxylase / HUMPS family
IGHMFEHH_00832	0.0	-	-	-	S	-	-	-	OPT oligopeptide transporter protein
IGHMFEHH_00834	0.0	-	-	-	G	-	-	-	Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain
IGHMFEHH_00836	1.71e-64	-	-	-	K	-	-	-	DNA-binding transcription factor activity
IGHMFEHH_00837	3.45e-145	-	-	-	-	-	-	-	-
IGHMFEHH_00839	0.0	-	-	-	S	-	-	-	Bacteriophage head to tail connecting protein
IGHMFEHH_00841	1.5e-180	-	-	-	-	-	-	-	-
IGHMFEHH_00843	1.26e-112	-	-	-	CO	-	-	-	cell redox homeostasis
IGHMFEHH_00844	6.11e-76	-	-	-	S	-	-	-	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
IGHMFEHH_00845	6.22e-74	-	-	-	S	-	-	-	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
IGHMFEHH_00846	1.3e-116	-	-	-	S	-	-	-	nitrogen fixation
IGHMFEHH_00847	3.89e-149	dedA	-	-	S	-	-	-	FtsZ-dependent cytokinesis
IGHMFEHH_00848	2.73e-267	-	2.4.1.182	GT19	M	ko:K00748	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IGHMFEHH_00849	0.0	-	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
IGHMFEHH_00850	2.89e-252	-	-	-	L	-	-	-	Transposase IS200 like
IGHMFEHH_00851	0.000131	-	-	-	S	-	-	-	Protein of unknown function (DUF2971)
IGHMFEHH_00853	0.0	-	-	-	P	ko:K03281	-	ko00000	Voltage gated chloride channel
IGHMFEHH_00854	1.34e-109	ptsN	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770,ko:K02806	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system
IGHMFEHH_00856	1.59e-150	-	-	-	-	-	-	-	-
IGHMFEHH_00857	0.0	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
IGHMFEHH_00859	0.0	-	-	-	MU	ko:K18139	ko01501,ko02024,map01501,map02024	ko00000,ko00001,ko00002,ko01504,ko02000	Outer membrane efflux protein
IGHMFEHH_00860	0.0	-	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IGHMFEHH_00861	3.88e-283	-	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IGHMFEHH_00862	0.0	prlC	3.4.24.70	-	E	ko:K01414	-	ko00000,ko01000,ko01002	Peptidase family M3
IGHMFEHH_00863	0.0	-	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	LeuA allosteric (dimerisation) domain
IGHMFEHH_00865	6.78e-42	-	-	-	S	-	-	-	PurA ssDNA and RNA-binding protein
IGHMFEHH_00866	6.11e-256	-	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Iron-sulfur cluster assembly protein
IGHMFEHH_00867	0.0	-	-	-	V	ko:K03327	-	ko00000,ko02000	MatE
IGHMFEHH_00870	0.0	-	4.1.1.3	-	C	ko:K01571	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	HMGL-like
IGHMFEHH_00871	0.0	-	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Phospholipase D. Active site motifs.
IGHMFEHH_00872	5.77e-208	-	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Thymidylate synthase
IGHMFEHH_00873	5.02e-115	-	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Dihydrofolate reductase
IGHMFEHH_00874	0.0	-	-	-	V	-	-	-	AcrB/AcrD/AcrF family
IGHMFEHH_00875	4.2e-264	-	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Biotin-lipoyl like
IGHMFEHH_00876	1.69e-107	-	-	-	K	-	-	-	DNA-binding transcription factor activity
IGHMFEHH_00878	1.53e-241	-	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Amidohydrolase
IGHMFEHH_00879	8.17e-159	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
IGHMFEHH_00880	1.48e-291	-	-	-	L	-	-	-	helicase superfamily c-terminal domain
IGHMFEHH_00881	1.71e-110	ruvC	3.1.22.4	-	L	ko:K01159	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
IGHMFEHH_00882	6.95e-122	-	-	-	-	-	-	-	-
IGHMFEHH_00883	0.0	sepA	-	-	Q	-	-	-	COG2015, Alkyl sulfatase and related hydrolases
IGHMFEHH_00884	7.42e-112	-	-	-	F	ko:K08311	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	NUDIX domain
IGHMFEHH_00885	1.21e-241	-	-	-	E	ko:K07588	-	ko00000,ko01000	ArgK protein
IGHMFEHH_00886	1.16e-282	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycoside hydrolase, family 20, catalytic core
IGHMFEHH_00887	4.1e-233	-	-	-	-	-	-	-	-
IGHMFEHH_00888	6.72e-285	pgk	2.7.2.3	-	G	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Phosphoglycerate kinase
IGHMFEHH_00889	1.67e-249	-	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
IGHMFEHH_00890	4.46e-148	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
IGHMFEHH_00892	3.37e-133	-	-	-	M	-	-	-	Polysaccharide biosynthesis/export protein
IGHMFEHH_00893	0.0	-	-	-	D	-	-	-	Chain length determinant protein
IGHMFEHH_00894	3.27e-297	-	-	-	-	-	-	-	-
IGHMFEHH_00898	0.0	-	-	-	P	ko:K03306	-	ko00000	phosphate transporter
IGHMFEHH_00899	5.31e-99	-	-	-	S	-	-	-	peptidase
IGHMFEHH_00900	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
IGHMFEHH_00901	2.2e-61	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IGHMFEHH_00902	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	MreB/Mbl protein
IGHMFEHH_00903	0.0	-	-	-	M	-	-	-	Glycosyl transferase 4-like domain
IGHMFEHH_00904	2.21e-277	-	-	-	S	-	-	-	COG0790 FOG TPR repeat, SEL1 subfamily
IGHMFEHH_00905	1.25e-241	-	-	-	O	ko:K04655	-	ko00000	AIR synthase related protein, N-terminal domain
IGHMFEHH_00906	7.79e-262	-	-	-	O	ko:K04654	-	ko00000	Hydrogenase formation hypA family
IGHMFEHH_00907	2.74e-50	-	-	-	O	ko:K04653	-	ko00000	HupF/HypC family
IGHMFEHH_00908	0.0	-	-	-	O	ko:K04656	-	ko00000	HypF finger
IGHMFEHH_00909	2.91e-175	hypB	-	-	KO	ko:K04652	-	ko00000,ko03110	CobW/HypB/UreG, nucleotide-binding domain
IGHMFEHH_00910	1.05e-310	-	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Histidyl-tRNA synthetase
IGHMFEHH_00911	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IGHMFEHH_00916	1.91e-260	-	2.3.1.47	-	H	ko:K00652	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
IGHMFEHH_00917	3.45e-283	-	-	-	IQ	-	-	-	Beta-ketoacyl synthase, C-terminal domain
IGHMFEHH_00918	0.0	-	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	thiolester hydrolase activity
IGHMFEHH_00919	1.2e-283	-	-	-	S	-	-	-	Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units
IGHMFEHH_00920	7.73e-147	-	-	-	IQ	-	-	-	RmlD substrate binding domain
IGHMFEHH_00921	0.0	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	GcpE protein
IGHMFEHH_00922	0.0	-	-	-	M	-	-	-	Bacterial membrane protein, YfhO
IGHMFEHH_00923	6.16e-198	-	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IGHMFEHH_00924	4.03e-120	-	-	-	-	-	-	-	-
IGHMFEHH_00925	3.85e-194	-	2.7.8.8	-	I	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	CDP-alcohol phosphatidyltransferase
IGHMFEHH_00926	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IGHMFEHH_00927	1.37e-227	-	-	-	M	ko:K01993	-	ko00000	HlyD family secretion protein
IGHMFEHH_00928	0.0	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IGHMFEHH_00929	1.03e-243	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
IGHMFEHH_00930	1.25e-245	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
IGHMFEHH_00933	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IGHMFEHH_00934	0.0	-	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	DNA Topoisomerase IV
IGHMFEHH_00935	9.28e-148	-	-	-	C	-	-	-	lactate oxidation
IGHMFEHH_00936	5.89e-296	-	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase family U32
IGHMFEHH_00937	5.28e-20	-	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	COG0010 Arginase agmatinase formimionoglutamate hydrolase arginase family
IGHMFEHH_00938	0.0	-	-	-	U	-	-	-	Involved in the tonB-independent uptake of proteins
IGHMFEHH_00939	0.0	-	-	-	C	-	-	-	cytochrome C peroxidase
IGHMFEHH_00940	5.67e-281	-	-	-	J	-	-	-	PFAM Endoribonuclease L-PSP
IGHMFEHH_00942	0.0	-	1.8.1.2	-	P	ko:K00381	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Nitrite and sulphite reductase 4Fe-4S domain
IGHMFEHH_00943	1.33e-182	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IGHMFEHH_00944	2.4e-188	-	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IGHMFEHH_00945	6.15e-260	-	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	NMT1/THI5 like
IGHMFEHH_00946	0.0	-	2.7.1.25, 2.7.7.4	-	P	ko:K00955	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily
IGHMFEHH_00947	2.1e-217	-	2.7.7.4	-	EH	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoadenosine phosphosulfate reductase family
IGHMFEHH_00948	8.78e-172	-	1.8.4.10, 1.8.4.8	-	EH	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Phosphoadenosine phosphosulfate reductase family
IGHMFEHH_00949	1.31e-214	-	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
IGHMFEHH_00950	6.58e-152	phoU	-	-	P	ko:K02039	-	ko00000	negative regulation of phosphate transmembrane transport
IGHMFEHH_00951	2.81e-184	-	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IGHMFEHH_00952	0.0	-	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IGHMFEHH_00953	0.0	pstC	-	-	P	ko:K02037,ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IGHMFEHH_00954	1.77e-220	-	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	PBP superfamily domain
IGHMFEHH_00955	6.37e-186	-	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IGHMFEHH_00956	1.49e-139	-	-	-	P	ko:K02039	-	ko00000	PhoU domain
IGHMFEHH_00957	2.5e-233	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Converts alpha-aldose to the beta-anomer
IGHMFEHH_00958	7.65e-101	-	-	-	M	ko:K06077	-	ko00000	Glycine zipper 2TM domain
IGHMFEHH_00960	0.0	-	-	-	S	ko:K07263	-	ko00000,ko01000,ko01002	Insulinase (Peptidase family M16)
IGHMFEHH_00961	1.01e-87	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
IGHMFEHH_00962	1.07e-149	-	-	-	H	-	-	-	HD superfamily hydrolase involved in NAD metabolism
IGHMFEHH_00963	1.17e-96	-	-	-	S	-	-	-	Maltose acetyltransferase
IGHMFEHH_00964	5.63e-226	-	-	-	L	-	-	-	Elongator protein 3, MiaB family, Radical SAM
IGHMFEHH_00965	2.49e-230	-	-	-	J	-	-	-	Belongs to the universal ribosomal protein uS2 family
IGHMFEHH_00966	1.7e-101	-	-	-	K	-	-	-	DNA-binding transcription factor activity
IGHMFEHH_00967	9.17e-70	-	-	-	M	-	-	-	Polymer-forming cytoskeletal
IGHMFEHH_00968	2.53e-120	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
IGHMFEHH_00969	4.62e-165	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Amino acid kinase family
IGHMFEHH_00970	1.21e-210	-	-	-	M	-	-	-	Mechanosensitive ion channel
IGHMFEHH_00971	3.6e-152	-	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	C-terminal domain of 1-Cys peroxiredoxin
IGHMFEHH_00972	0.0	-	-	-	S	-	-	-	Sodium:neurotransmitter symporter family
IGHMFEHH_00973	0.0	-	-	-	-	-	-	-	-
IGHMFEHH_00974	2.37e-46	-	-	-	J	-	-	-	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IGHMFEHH_00975	3.08e-146	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IGHMFEHH_00977	3.9e-306	-	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IGHMFEHH_00978	5.68e-109	msrB	1.8.4.11, 1.8.4.12	-	O	ko:K07305,ko:K12267	-	ko00000,ko01000	peptide-methionine (R)-S-oxide reductase activity
IGHMFEHH_00979	2.93e-259	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IGHMFEHH_00980	9.52e-301	nupG	-	-	G	ko:K03289,ko:K03301,ko:K08218,ko:K11537	ko01501,map01501	ko00000,ko00001,ko00002,ko02000	Major facilitator Superfamily
IGHMFEHH_00983	8.36e-173	-	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	FtsJ-like methyltransferase
IGHMFEHH_00985	3.05e-170	-	-	-	S	ko:K06911	-	ko00000	Pirin
IGHMFEHH_00986	0.0	-	-	-	M	-	-	-	AsmA-like C-terminal region
IGHMFEHH_00988	1.03e-201	-	-	-	G	-	-	-	Class II Aldolase and Adducin N-terminal domain
IGHMFEHH_00989	0.0	-	2.7.1.51	-	G	ko:K00879	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
IGHMFEHH_00990	0.0	fucI	5.3.1.25, 5.3.1.3	-	G	ko:K01818	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Converts the aldose L-fucose into the corresponding ketose L-fuculose
IGHMFEHH_00991	0.0	-	-	-	G	-	-	-	Major Facilitator Superfamily
IGHMFEHH_00992	6.72e-123	-	-	-	-	-	-	-	-
IGHMFEHH_00993	0.0	-	3.2.1.18	GH33	G	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	ko00000,ko00001,ko01000,ko02042	N-terminal domain of BNR-repeat neuraminidase
IGHMFEHH_00994	1.45e-133	-	-	-	K	ko:K03088	-	ko00000,ko03021	ECF sigma factor
IGHMFEHH_00995	1.67e-33	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
IGHMFEHH_00996	7.29e-60	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	negative regulation of transcription, DNA-templated
IGHMFEHH_00997	0.0	copA	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
IGHMFEHH_00998	0.0	-	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	ThiC-associated domain
IGHMFEHH_00999	2.85e-216	ytpP	2.7.1.180, 5.3.4.1	-	CO	ko:K01829,ko:K03671,ko:K03734,ko:K06196	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko01000,ko02000,ko03110	cell redox homeostasis
IGHMFEHH_01000	1.07e-138	-	-	-	K	-	-	-	ECF sigma factor
IGHMFEHH_01002	1e-219	-	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
IGHMFEHH_01003	2.98e-233	-	-	-	O	-	-	-	Parallel beta-helix repeats
IGHMFEHH_01004	0.0	-	3.1.5.1	-	F	ko:K01129	ko00230,map00230	ko00000,ko00001,ko01000	Phosphohydrolase-associated domain
IGHMFEHH_01005	2.4e-285	-	-	-	Q	-	-	-	Multicopper oxidase
IGHMFEHH_01006	3.59e-207	-	-	-	EG	-	-	-	EamA-like transporter family
IGHMFEHH_01007	2.57e-120	-	-	-	L	-	-	-	Protein of unknown function DUF262
IGHMFEHH_01009	3.12e-274	-	5.1.1.1	-	M	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IGHMFEHH_01010	6.48e-244	-	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
IGHMFEHH_01011	1.82e-229	-	-	-	EP	ko:K02031	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
IGHMFEHH_01012	0.0	-	-	-	E	ko:K13893	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
IGHMFEHH_01013	0.0	-	-	-	P	ko:K13895	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IGHMFEHH_01014	0.0	-	-	-	EP	ko:K13894	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IGHMFEHH_01015	1.4e-185	-	-	-	T	-	-	-	Calcineurin-like phosphoesterase superfamily domain
IGHMFEHH_01016	1.65e-208	-	-	-	S	-	-	-	Tetratricopeptide repeat
IGHMFEHH_01017	9.98e-223	-	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Ketopantoate reductase PanE/ApbA C terminal
IGHMFEHH_01018	0.0	fhs	6.3.4.3	-	H	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Formate--tetrahydrofolate ligase
IGHMFEHH_01019	1.36e-143	-	-	-	S	ko:K09974	-	ko00000	Domain of unknown function (DUF1287)
IGHMFEHH_01020	1.67e-313	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain
IGHMFEHH_01021	2.18e-117	-	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-strand binding protein family
IGHMFEHH_01022	2.63e-283	-	5.4.99.22	-	M	ko:K06178	-	ko00000,ko01000,ko03009	translation initiation factor activity
IGHMFEHH_01023	4.44e-134	-	-	-	U	ko:K03561	-	ko00000,ko02000	MotA/TolQ/ExbB proton channel family
IGHMFEHH_01024	7.4e-93	-	-	-	U	ko:K03559	-	ko00000,ko02000	Biopolymer transport protein ExbD/TolR
IGHMFEHH_01025	8.02e-130	-	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IGHMFEHH_01026	4.08e-291	-	3.2.1.1	GH57	G	ko:K07405	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolase family 57
IGHMFEHH_01027	1.25e-315	-	-	-	G	-	-	-	Glycosyl transferase 4-like domain
IGHMFEHH_01028	0.0	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolases family 31
IGHMFEHH_01029	1.22e-249	-	5.4.4.2	-	HQ	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	chorismate binding enzyme
IGHMFEHH_01030	2.74e-313	-	-	-	C	ko:K00185	-	ko00000	Polysulphide reductase, NrfD
IGHMFEHH_01032	7.47e-156	-	-	-	C	-	-	-	Cytochrome c
IGHMFEHH_01033	4.49e-298	-	-	-	P	-	-	-	ABC-type Zn2 transport system, periplasmic component surface adhesin
IGHMFEHH_01034	0.0	-	-	-	C	-	-	-	Cytochrome c
IGHMFEHH_01035	6.84e-61	-	-	-	E	ko:K07032	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IGHMFEHH_01036	1.6e-270	-	-	-	S	-	-	-	Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units
IGHMFEHH_01037	6.74e-307	-	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Isocitrate/isopropylmalate dehydrogenase
IGHMFEHH_01038	1.23e-159	-	-	-	S	-	-	-	Protein of unknown function (DUF4230)
IGHMFEHH_01039	7.12e-62	-	-	-	S	-	-	-	Protein of unknown function (DUF1232)
IGHMFEHH_01040	0.0	-	-	-	J	-	-	-	Beta-Casp domain
IGHMFEHH_01041	3.18e-141	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IGHMFEHH_01042	1.02e-159	queC	6.3.4.20	-	F	ko:K06920	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Queuosine biosynthesis protein QueC
IGHMFEHH_01043	2.08e-96	queF	1.7.1.13	-	S	ko:K09457	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	QueF-like protein
IGHMFEHH_01044	0.0	kefA	-	-	M	ko:K05802,ko:K22051	-	ko00000,ko02000	cellular water homeostasis
IGHMFEHH_01045	0.0	gltX	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IGHMFEHH_01046	1.5e-237	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IGHMFEHH_01047	3.39e-190	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Bacitracin resistance protein BacA
IGHMFEHH_01050	3.66e-85	-	-	-	S	ko:K06940	-	ko00000	Putative zinc- or iron-chelating domain
IGHMFEHH_01051	7.74e-314	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
IGHMFEHH_01052	1.93e-302	-	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
IGHMFEHH_01053	7.71e-52	-	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
IGHMFEHH_01054	1.25e-261	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IGHMFEHH_01056	8.29e-100	cysJ	1.8.1.2	-	C	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	hydroxylamine reductase activity
IGHMFEHH_01058	2.43e-201	lpxG	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase
IGHMFEHH_01059	5.27e-170	BT0174	-	-	C	ko:K04488	-	ko00000	iron-sulfur transferase activity
IGHMFEHH_01060	2.08e-240	BT0173	-	-	S	-	-	-	Psort location Cytoplasmic, score
IGHMFEHH_01062	3.31e-270	-	2.1.1.72	-	H	ko:K07318	-	ko00000,ko01000,ko02048	PFAM D12 class N6 adenine-specific DNA methyltransferase
IGHMFEHH_01063	6.72e-210	-	-	-	L	ko:K04763	-	ko00000,ko03036	Phage integrase, N-terminal SAM-like domain
IGHMFEHH_01067	2.1e-275	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Iron-containing alcohol dehydrogenase
IGHMFEHH_01068	6.02e-78	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IGHMFEHH_01069	6.12e-230	-	-	-	G	-	-	-	pfkB family carbohydrate kinase
IGHMFEHH_01070	0.0	fabZ	3.5.1.108, 4.2.1.59	-	IM	ko:K16363	ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis
IGHMFEHH_01071	1.1e-228	-	2.7.7.13	-	JM	ko:K00966	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
IGHMFEHH_01072	1.56e-176	-	-	-	S	-	-	-	Phosphodiester glycosidase
IGHMFEHH_01073	0.0	-	-	GT2	M	ko:K03820	-	ko00000,ko01000	Carbon-nitrogen hydrolase
IGHMFEHH_01074	4.64e-52	-	-	-	C	-	-	-	4Fe-4S single cluster domain of Ferredoxin I
IGHMFEHH_01075	4.58e-103	-	-	-	S	-	-	-	Protein of unknown function (DUF721)
IGHMFEHH_01076	0.0	-	-	-	G	-	-	-	beta-N-acetylhexosaminidase activity
IGHMFEHH_01077	2.94e-236	-	-	-	S	-	-	-	Acyltransferase family
IGHMFEHH_01078	0.0	-	-	-	O	-	-	-	Cytochrome C assembly protein
IGHMFEHH_01079	7.52e-166	ccs1	-	-	O	ko:K07399	-	ko00000	cytochrome c biogenesis protein
IGHMFEHH_01080	2.07e-210	fatB	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	iron ion transport
IGHMFEHH_01081	1.5e-180	yclP	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IGHMFEHH_01082	6.08e-229	fatC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	iron ion homeostasis
IGHMFEHH_01083	5.35e-220	yclN	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	iron ion homeostasis
IGHMFEHH_01084	2.43e-264	-	-	-	J	-	-	-	Endoribonuclease L-PSP
IGHMFEHH_01085	0.0	-	-	-	C	-	-	-	Di-haem oxidoreductase, putative peroxidase
IGHMFEHH_01086	1.52e-245	-	-	-	S	-	-	-	Imelysin
IGHMFEHH_01087	1.59e-142	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
IGHMFEHH_01089	1.82e-125	-	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Phosphoribosyl transferase domain
IGHMFEHH_01090	0.0	-	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	Helix-hairpin-helix class 2 (Pol1 family) motifs
IGHMFEHH_01091	1.37e-249	-	-	-	M	-	-	-	HlyD family secretion protein
IGHMFEHH_01092	2.52e-102	MA20_05485	-	-	S	-	-	-	Putative bacterial sensory transduction regulator
IGHMFEHH_01093	0.0	-	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Adenylosuccinate lyase C-terminus
IGHMFEHH_01094	1.71e-301	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
IGHMFEHH_01095	0.0	-	-	-	D	-	-	-	Tetratricopeptide repeat
IGHMFEHH_01096	1.47e-193	-	-	-	I	-	-	-	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
IGHMFEHH_01097	0.0	-	-	-	-	-	-	-	-
IGHMFEHH_01098	1.38e-223	-	4.1.3.3	-	EM	ko:K01639	ko00520,map00520	ko00000,ko00001,ko01000	Dihydrodipicolinate synthetase family
IGHMFEHH_01099	6.68e-314	-	5.1.3.8	-	G	ko:K01787	ko00520,map00520	ko00000,ko00001,ko01000	N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
IGHMFEHH_01100	0.0	-	-	-	S	-	-	-	Protein of unknown function DUF262
IGHMFEHH_01101	1.25e-146	-	4.1.3.38	-	E	ko:K02619	ko00790,map00790	ko00000,ko00001,ko01000	branched-chain-amino-acid transaminase activity
IGHMFEHH_01102	2.55e-247	pabB	2.6.1.85, 4.1.3.27, 4.1.3.38	-	EH	ko:K01665,ko:K03342,ko:K13503,ko:K13950	ko00400,ko00790,ko01100,ko01110,ko01130,ko01230,map00400,map00790,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IGHMFEHH_01103	2.44e-149	-	4.1.3.27	-	EH	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Peptidase C26
IGHMFEHH_01104	3.68e-269	-	-	-	C	-	-	-	NADH:flavin oxidoreductase / NADH oxidase family
IGHMFEHH_01105	6.4e-173	-	-	-	S	-	-	-	Integral membrane protein (intg_mem_TP0381)
IGHMFEHH_01106	7.35e-119	-	-	-	T	ko:K07005	-	ko00000	pyridoxamine 5'-phosphate
IGHMFEHH_01107	3.7e-174	-	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Glutamine amidotransferase class-I
IGHMFEHH_01109	8.23e-112	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Cys-tRNA(Pro) hydrolase activity
IGHMFEHH_01110	0.0	mmyX	5.3.1.12	-	F	ko:K01812,ko:K07149,ko:K16139	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000,ko02000	Psort location Cytoplasmic, score
IGHMFEHH_01111	1.64e-92	-	-	-	-	-	-	-	-
IGHMFEHH_01112	2.36e-72	-	-	-	-	-	-	-	-
IGHMFEHH_01114	2.53e-146	-	-	-	Q	-	-	-	PA14
IGHMFEHH_01115	0.0	-	2.1.1.13	-	E	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	B12 binding domain
IGHMFEHH_01116	1.66e-171	-	-	-	S	-	-	-	Putative threonine/serine exporter
IGHMFEHH_01117	2.34e-108	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
IGHMFEHH_01119	0.0	-	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
IGHMFEHH_01120	2.52e-281	-	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
IGHMFEHH_01121	1.12e-116	agmK	1.8.1.8	-	O	ko:K03671,ko:K03672	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko01000,ko03110	belongs to the thioredoxin family
IGHMFEHH_01122	3.71e-179	-	-	-	S	-	-	-	Integral membrane protein (intg_mem_TP0381)
IGHMFEHH_01124	0.0	-	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen
IGHMFEHH_01126	4.39e-217	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IGHMFEHH_01127	9.76e-258	-	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	endonuclease III
IGHMFEHH_01128	1.22e-143	aat	2.3.2.6	-	O	ko:K00684	-	ko00000,ko01000	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
IGHMFEHH_01129	0.0	-	2.7.9.1	-	G	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Pyruvate phosphate dikinase, PEP/pyruvate binding domain
IGHMFEHH_01130	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Phosphoglucose isomerase
IGHMFEHH_01131	9.09e-260	-	-	-	S	-	-	-	COG0790 FOG TPR repeat, SEL1 subfamily
IGHMFEHH_01132	4.33e-225	-	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	S-adenosylmethionine-dependent methyltransferase
IGHMFEHH_01134	0.0	-	5.4.99.2	-	I	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Methylmalonyl-CoA mutase
IGHMFEHH_01135	0.0	-	5.4.99.2	-	I	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Methylmalonyl-CoA mutase
IGHMFEHH_01136	0.0	-	-	-	D	-	-	-	nuclear chromosome segregation
IGHMFEHH_01137	2.94e-131	-	-	-	-	-	-	-	-
IGHMFEHH_01138	1.12e-243	-	-	-	I	-	-	-	PFAM Prenyltransferase squalene oxidase
IGHMFEHH_01141	8.93e-181	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Pyrroline-5-carboxylate reductase dimerisation
IGHMFEHH_01142	4.69e-159	-	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Methyladenine glycosylase
IGHMFEHH_01143	5.51e-211	-	-	-	S	-	-	-	ABC-type transport system involved in multi-copper enzyme maturation permease component
IGHMFEHH_01144	1.33e-226	-	-	-	S	-	-	-	Protein conserved in bacteria
IGHMFEHH_01145	2.01e-34	-	-	-	KLT	-	-	-	Tyrosine-protein kinase, subgroup, catalytic domain
IGHMFEHH_01146	0.0	-	4.1.99.1	-	E	ko:K01667	ko00380,map00380	ko00000,ko00001,ko01000	Beta-eliminating lyase
IGHMFEHH_01147	6.76e-143	-	-	-	M	-	-	-	Peptidoglycan-binding domain 1 protein
IGHMFEHH_01148	7.12e-255	-	-	-	S	-	-	-	Domain of unknown function (DUF4105)
IGHMFEHH_01149	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	B3/4 domain
IGHMFEHH_01150	2.34e-240	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Aminoacyl tRNA synthetase class II, N-terminal domain
IGHMFEHH_01151	4.93e-287	-	-	-	P	ko:K03449	-	ko00000,ko02000	Major Facilitator Superfamily
IGHMFEHH_01152	0.0	-	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	transmembrane transport
IGHMFEHH_01153	0.0	htpG	-	-	O	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	Hsp90 protein
IGHMFEHH_01154	6.97e-174	-	-	-	P	ko:K10716	-	ko00000,ko02000	domain protein
IGHMFEHH_01156	2.32e-259	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
IGHMFEHH_01157	1.51e-73	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IGHMFEHH_01158	7.45e-231	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	maintenance of DNA repeat elements
IGHMFEHH_01159	0.0	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	defense response to virus
IGHMFEHH_01160	1.37e-273	-	5.1.1.1	-	M	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IGHMFEHH_01161	9.25e-103	-	-	-	K	-	-	-	Transcriptional regulator
IGHMFEHH_01162	7.1e-311	-	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Cys/Met metabolism PLP-dependent enzyme
IGHMFEHH_01163	2.17e-213	-	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
IGHMFEHH_01164	3.42e-135	thiE	2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17	-	H	ko:K00788,ko:K03147,ko:K14153	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
IGHMFEHH_01165	1.15e-173	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
IGHMFEHH_01166	2.47e-116	gepA	-	-	K	-	-	-	Phage-associated protein
IGHMFEHH_01168	0.0	-	-	-	S	-	-	-	Carbohydrate esterase, sialic acid-specific acetylesterase
IGHMFEHH_01169	1.04e-109	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IGHMFEHH_01170	7.2e-125	-	-	-	-	-	-	-	-
IGHMFEHH_01171	0.0	-	-	-	U	ko:K03321	-	ko00000,ko02000	Sulfate permease family
IGHMFEHH_01172	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Argininosuccinate lyase C-terminal
IGHMFEHH_01173	1.76e-163	-	-	-	S	-	-	-	SWIM zinc finger
IGHMFEHH_01174	0.0	-	-	-	-	-	-	-	-
IGHMFEHH_01175	2.46e-307	-	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IGHMFEHH_01176	4.2e-204	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
IGHMFEHH_01177	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
IGHMFEHH_01178	1.34e-257	-	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
IGHMFEHH_01179	0.0	-	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein
IGHMFEHH_01180	0.0	miaB	2.8.4.3	-	J	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IGHMFEHH_01181	9.09e-301	-	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	tRNA (Uracil-5-)-methyltransferase
IGHMFEHH_01184	0.0	-	-	-	-	-	-	-	-
IGHMFEHH_01185	7.36e-55	himA	-	-	L	ko:K03530,ko:K04764,ko:K05788	-	ko00000,ko03032,ko03036,ko03400	regulation of translation
IGHMFEHH_01186	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Glycosyl hydrolase family 36 N-terminal domain
IGHMFEHH_01187	0.0	-	-	-	P	ko:K07085	-	ko00000	Predicted Permease Membrane Region
IGHMFEHH_01188	2.68e-110	-	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	cheY-homologous receiver domain
IGHMFEHH_01189	0.0	-	-	-	T	-	-	-	Histidine kinase
IGHMFEHH_01190	0.0	-	-	-	P	ko:K14445	-	ko00000,ko02000	Citrate transporter
IGHMFEHH_01191	1.07e-188	-	1.97.1.4	-	O	ko:K04069	-	ko00000,ko01000	Radical SAM superfamily
IGHMFEHH_01192	3.8e-43	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	CTP reductase activity
IGHMFEHH_01193	0.0	-	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Anaerobic ribonucleoside-triphosphate reductase
IGHMFEHH_01194	0.0	-	-	-	M	-	-	-	Glycosyl Hydrolase Family 88
IGHMFEHH_01195	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF1705)
IGHMFEHH_01196	1.96e-121	ngr	-	-	C	-	-	-	Rubrerythrin
IGHMFEHH_01198	8.88e-268	-	-	-	G	-	-	-	M42 glutamyl aminopeptidase
IGHMFEHH_01199	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycoside hydrolase, family 20, catalytic core
IGHMFEHH_01200	4.06e-287	-	-	-	EGP	-	-	-	Major facilitator Superfamily
IGHMFEHH_01201	2.05e-277	-	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Alkaline phosphatase homologues
IGHMFEHH_01202	3.06e-85	-	-	-	M	ko:K03282	-	ko00000,ko02000	Large-conductance mechanosensitive channel, MscL
IGHMFEHH_01203	4.8e-313	-	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
IGHMFEHH_01204	1.2e-105	-	-	-	S	-	-	-	ACT domain protein
IGHMFEHH_01206	9.29e-132	-	-	-	J	ko:K02356	-	ko00000,ko03012	Elongation factor P (EF-P) OB domain
IGHMFEHH_01207	9.15e-242	-	-	-	G	-	-	-	Glycosyl hydrolases family 16
IGHMFEHH_01208	0.0	-	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
IGHMFEHH_01209	0.0	-	-	-	L	ko:K03631	-	ko00000,ko03400	RecF/RecN/SMC N terminal domain
IGHMFEHH_01210	8.73e-189	-	3.1.4.55	-	S	ko:K06167	ko00440,map00440	ko00000,ko00001,ko01000	Metallo-beta-lactamase superfamily
IGHMFEHH_01211	8.05e-189	-	-	-	M	-	-	-	Glycosyl transferase WecB/TagA/CpsF family
IGHMFEHH_01212	3.04e-171	yyaQ	-	-	V	-	-	-	Protein conserved in bacteria
IGHMFEHH_01213	3.84e-90	-	-	-	-	-	-	-	-
IGHMFEHH_01216	8.16e-207	-	-	-	S	ko:K09949	-	ko00000	Protein of unknown function (DUF1009)
IGHMFEHH_01217	1.63e-298	-	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	2-oxoacid dehydrogenases acyltransferase (catalytic domain)
IGHMFEHH_01218	9.47e-236	-	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, pyrimidine binding domain
IGHMFEHH_01219	6.82e-223	-	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
IGHMFEHH_01220	9.44e-193	-	-	-	K	-	-	-	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
IGHMFEHH_01221	5.81e-242	-	-	-	M	ko:K18094	ko01501,ko02020,map01501,map02020	ko00000,ko00001,ko00002,ko01504,ko02000	Biotin-lipoyl like
IGHMFEHH_01222	0.0	-	-	-	V	ko:K18095	ko01501,ko02020,map01501,map02020	ko00000,ko00001,ko00002,ko01504,ko02000	AcrB/AcrD/AcrF family
IGHMFEHH_01223	0.0	-	-	-	S	-	-	-	pathogenesis
IGHMFEHH_01224	8.21e-97	-	-	-	S	-	-	-	peptidase
IGHMFEHH_01225	3e-171	-	-	-	S	ko:K06973	-	ko00000	Putative neutral zinc metallopeptidase
IGHMFEHH_01226	6.42e-101	-	-	-	S	-	-	-	peptidase
IGHMFEHH_01227	0.0	-	2.1.1.107, 4.2.1.75	-	H	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase HemD
IGHMFEHH_01228	5.17e-101	-	-	-	-	-	-	-	-
IGHMFEHH_01229	0.0	-	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	Bacterial DNA topoisomeraes I ATP-binding domain
IGHMFEHH_01233	8.8e-169	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	PFAM N-acetylmuramoyl-L-alanine amidase family 2
IGHMFEHH_01234	0.0	-	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Aconitase C-terminal domain
IGHMFEHH_01235	4.44e-134	-	-	-	D	-	-	-	ErfK ybiS ycfS ynhG family protein
IGHMFEHH_01237	6.16e-285	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IGHMFEHH_01239	0.0	-	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	transmembrane transport
IGHMFEHH_01240	4.77e-271	-	-	-	S	-	-	-	tRNA-splicing ligase RtcB
IGHMFEHH_01241	1.93e-214	-	-	-	K	-	-	-	LysR substrate binding domain
IGHMFEHH_01242	7.13e-295	-	-	-	EGP	-	-	-	Major facilitator Superfamily
IGHMFEHH_01244	4.11e-129	-	-	-	S	-	-	-	Cobalamin adenosyltransferase
IGHMFEHH_01245	6.52e-75	-	-	-	L	-	-	-	Cupin 2, conserved barrel domain protein
IGHMFEHH_01246	0.0	rnr	-	-	K	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
IGHMFEHH_01248	0.0	-	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Collagenase
IGHMFEHH_01249	1.53e-286	-	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Mur ligase middle domain
IGHMFEHH_01251	0.0	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
IGHMFEHH_01252	0.0	-	2.7.11.1	-	L	ko:K08282	-	ko00000,ko01000	SNF2 Helicase protein
IGHMFEHH_01253	0.0	-	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
IGHMFEHH_01254	2.42e-122	-	-	-	M	ko:K03642	-	ko00000	Lytic transglycolase
IGHMFEHH_01255	4.9e-207	nadK	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IGHMFEHH_01256	1.53e-47	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal proteins 50S L24/mitochondrial 39S L24
IGHMFEHH_01257	5.36e-138	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IGHMFEHH_01258	4.08e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IGHMFEHH_01259	2.25e-105	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IGHMFEHH_01260	2.38e-74	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IGHMFEHH_01261	3.38e-102	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IGHMFEHH_01262	6.42e-101	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A
IGHMFEHH_01264	0.0	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
IGHMFEHH_01265	6.41e-155	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
IGHMFEHH_01266	1.29e-192	map	3.4.11.18	-	J	ko:K01265	-	ko00000,ko01000,ko01002	Metallopeptidase family M24
IGHMFEHH_01267	1.64e-263	-	-	-	S	ko:K11941	-	ko00000,ko01000	transferase activity, transferring acyl groups other than amino-acyl groups
IGHMFEHH_01268	0.0	-	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	Ppx/GppA phosphatase family
IGHMFEHH_01269	0.0	-	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Polyphosphate kinase middle domain
IGHMFEHH_01270	1.33e-277	-	-	-	H	-	-	-	PFAM glycosyl transferase family 8
IGHMFEHH_01272	1.95e-272	-	-	GT2	S	ko:K19427	-	ko00000,ko01000	PFAM glycosyl transferase family 2
IGHMFEHH_01273	1.77e-225	-	-	-	S	-	-	-	Glycosyl transferase family 11
IGHMFEHH_01274	6.65e-261	-	-	-	S	-	-	-	Glycosyltransferase like family 2
IGHMFEHH_01275	4.79e-292	-	-	-	-	-	-	-	-
IGHMFEHH_01276	7.54e-266	-	-	-	S	-	-	-	PFAM glycosyl transferase family 2
IGHMFEHH_01277	3.93e-128	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
IGHMFEHH_01278	8.31e-232	-	-	-	C	-	-	-	e3 binding domain
IGHMFEHH_01279	4.34e-284	-	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IGHMFEHH_01280	3.46e-136	-	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IGHMFEHH_01281	0.0	-	-	-	EGIP	-	-	-	Phosphate acyltransferases
IGHMFEHH_01282	0.0	-	-	-	T	-	-	-	5TM C-terminal transporter carbon starvation CstA
IGHMFEHH_01283	1.05e-155	-	-	-	-	-	-	-	-
IGHMFEHH_01284	3.4e-15	-	-	-	-	-	-	-	-
IGHMFEHH_01285	0.0	-	-	-	P	-	-	-	PA14 domain
IGHMFEHH_01286	2e-82	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IGHMFEHH_01287	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IGHMFEHH_01288	5.58e-289	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	NusA-like KH domain
IGHMFEHH_01289	3.73e-195	-	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease/Exonuclease/phosphatase family
IGHMFEHH_01290	1.72e-144	-	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IGHMFEHH_01291	1.49e-135	-	-	-	J	-	-	-	Putative rRNA methylase
IGHMFEHH_01292	1.1e-201	-	-	-	S	-	-	-	Domain of unknown function (DUF362)
IGHMFEHH_01293	0.0	-	-	-	C	-	-	-	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein
IGHMFEHH_01294	0.0	-	-	-	V	-	-	-	ABC-2 type transporter
IGHMFEHH_01296	0.0	-	-	-	-	-	-	-	-
IGHMFEHH_01297	1.02e-184	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
IGHMFEHH_01298	7.33e-143	-	-	-	S	-	-	-	RNA recognition motif
IGHMFEHH_01299	0.0	-	-	-	M	-	-	-	Bacterial sugar transferase
IGHMFEHH_01300	2.55e-283	-	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Galactokinase galactose-binding signature
IGHMFEHH_01301	0.0	-	-	-	S	ko:K03307	-	ko00000	Sodium:solute symporter family
IGHMFEHH_01303	0.0	-	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	UvrD-like helicase C-terminal domain
IGHMFEHH_01304	3.02e-227	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IGHMFEHH_01305	2.28e-271	-	-	-	M	-	-	-	Monogalactosyldiacylglycerol (MGDG) synthase
IGHMFEHH_01306	7.16e-174	coaX	2.7.1.33	-	K	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Type III pantothenate kinase
IGHMFEHH_01307	8.56e-45	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Phosphopantetheine attachment site
IGHMFEHH_01308	8.25e-131	-	-	-	-	-	-	-	-
IGHMFEHH_01309	2.37e-174	-	-	-	S	-	-	-	Lysin motif
IGHMFEHH_01310	4.36e-98	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
IGHMFEHH_01311	7.01e-74	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
IGHMFEHH_01313	9.84e-188	-	-	-	M	-	-	-	self proteolysis
IGHMFEHH_01314	8.89e-32	-	-	-	M	-	-	-	self proteolysis
IGHMFEHH_01315	8.51e-42	-	-	-	S	ko:K07114	-	ko00000,ko02000	von Willebrand factor (vWF) type A domain
IGHMFEHH_01316	0.0	-	-	-	S	-	-	-	Oxygen tolerance
IGHMFEHH_01317	1.16e-205	yeaE	-	-	S	-	-	-	aldo-keto reductase (NADP) activity
IGHMFEHH_01318	0.0	-	6.1.1.14	-	J	ko:K01880	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Anticodon binding domain
IGHMFEHH_01319	7.47e-156	-	-	-	S	-	-	-	DUF218 domain
IGHMFEHH_01320	5.33e-207	-	-	-	S	-	-	-	CAAX protease self-immunity
IGHMFEHH_01321	3.2e-286	-	-	-	E	ko:K10907	-	ko00000,ko01000,ko01007	Cys/Met metabolism PLP-dependent enzyme
IGHMFEHH_01322	8.26e-106	-	-	-	K	-	-	-	Lrp/AsnC ligand binding domain
IGHMFEHH_01323	0.0	-	-	-	L	-	-	-	SNF2 family N-terminal domain
IGHMFEHH_01324	8.46e-84	-	-	-	P	ko:K06195	-	ko00000	ApaG domain
IGHMFEHH_01325	7.47e-203	-	-	-	-	-	-	-	-
IGHMFEHH_01326	0.0	-	-	-	M	-	-	-	Glycosyl transferase family group 2
IGHMFEHH_01327	3.01e-192	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
IGHMFEHH_01328	1.88e-135	-	-	-	K	ko:K07735	-	ko00000,ko03000	Uncharacterized ACR, COG1678
IGHMFEHH_01329	5.04e-164	-	-	-	S	ko:K06997	-	ko00000	Alanine racemase, N-terminal domain
IGHMFEHH_01330	0.0	-	-	-	S	-	-	-	50S ribosome-binding GTPase
IGHMFEHH_01331	7.88e-137	-	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	5-formyltetrahydrofolate cyclo-ligase family
IGHMFEHH_01332	8.83e-209	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IGHMFEHH_01333	0.0	-	-	-	E	-	-	-	Peptidase dimerisation domain
IGHMFEHH_01334	3.12e-223	hprK	-	-	T	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr)
IGHMFEHH_01335	8.72e-53	-	-	-	G	ko:K11189	-	ko00000,ko02000	PTS HPr component phosphorylation site
IGHMFEHH_01336	0.0	-	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IGHMFEHH_01337	0.0	-	-	-	P	-	-	-	Sulfatase
IGHMFEHH_01338	1.64e-223	-	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IGHMFEHH_01339	5.06e-94	-	-	-	S	ko:K02426	-	ko00000	Fe-S metabolism associated domain
IGHMFEHH_01341	0.0	-	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Alpha amylase, C-terminal all-beta domain
IGHMFEHH_01342	1.14e-259	-	-	-	M	ko:K07271	-	ko00000,ko01000	LICD family
IGHMFEHH_01343	0.0	cobD	2.6.1.9, 2.7.7.74, 4.1.1.81	-	M	ko:K00817,ko:K04720,ko:K07281	ko00340,ko00350,ko00360,ko00400,ko00401,ko00562,ko00860,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00562,map00860,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	nucleotidyl transferase
IGHMFEHH_01344	1.5e-95	-	4.3.1.12	-	E	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	ko00000,ko00001,ko01000	Ornithine cyclodeaminase/mu-crystallin family
IGHMFEHH_01345	0.0	-	2.7.7.15	-	H	ko:K00968	ko00440,ko00564,ko01100,ko05231,map00440,map00564,map01100,map05231	ko00000,ko00001,ko00002,ko01000	Oxidoreductase family, NAD-binding Rossmann fold
IGHMFEHH_01346	2.54e-226	-	-	-	M	ko:K07271	-	ko00000,ko01000	LICD family
IGHMFEHH_01347	3.44e-132	-	-	-	S	-	-	-	protein trimerization
IGHMFEHH_01349	5.27e-183	-	2.1.1.144, 2.1.1.197	-	FG	ko:K00598,ko:K02169	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	trans-aconitate 2-methyltransferase activity
IGHMFEHH_01350	0.0	-	2.7.7.9	-	G	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP--glucose-1-phosphate uridylyltransferase
IGHMFEHH_01351	1.43e-124	-	-	-	-	-	-	-	-
IGHMFEHH_01352	1.12e-63	-	-	-	J	-	-	-	RF-1 domain
IGHMFEHH_01353	1.47e-121	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IGHMFEHH_01355	1.5e-275	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
IGHMFEHH_01356	1.1e-298	-	-	-	S	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
IGHMFEHH_01357	1.15e-146	-	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IGHMFEHH_01358	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IGHMFEHH_01360	6.94e-237	-	4.2.1.24	-	H	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko04147	Delta-aminolevulinic acid dehydratase
IGHMFEHH_01362	2.04e-160	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
IGHMFEHH_01363	0.0	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
IGHMFEHH_01364	2.44e-230	-	4.1.1.35	-	M	ko:K08678	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko00002,ko01000	3-beta hydroxysteroid dehydrogenase/isomerase family
IGHMFEHH_01365	1.51e-183	-	-	-	I	-	-	-	Acyl-ACP thioesterase
IGHMFEHH_01367	1.5e-54	-	-	-	U	-	-	-	Passenger-associated-transport-repeat
IGHMFEHH_01368	0.0	-	2.3.1.40, 6.2.1.20	-	IQ	ko:K05939	ko00071,ko00564,map00071,map00564	ko00000,ko00001,ko01000	AMP-binding enzyme
IGHMFEHH_01369	0.0	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IGHMFEHH_01370	6.39e-71	-	-	-	-	-	-	-	-
IGHMFEHH_01373	5.49e-206	-	-	-	S	ko:K03453	-	ko00000	Bile acid
IGHMFEHH_01374	1.55e-291	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IGHMFEHH_01375	2.18e-269	sucC	6.2.1.5	-	C	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
IGHMFEHH_01376	3.89e-209	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IGHMFEHH_01377	2.23e-176	-	-	-	-	-	-	-	-
IGHMFEHH_01379	0.0	-	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	RQC
IGHMFEHH_01384	1.97e-230	-	-	-	S	-	-	-	mannose-ethanolamine phosphotransferase activity
IGHMFEHH_01386	6.29e-115	-	-	-	S	ko:K03748	-	ko00000	DUF218 domain
IGHMFEHH_01388	3.15e-103	-	-	-	J	-	-	-	YjgF/chorismate_mutase-like, putative endoribonuclease
IGHMFEHH_01389	0.0	-	-	-	-	-	-	-	-
IGHMFEHH_01390	1e-112	-	1.16.3.2	-	P	ko:K02217	-	ko00000,ko01000	Ferritin-like domain
IGHMFEHH_01392	4.98e-92	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
IGHMFEHH_01393	1.25e-307	-	4.2.1.20	-	E	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
IGHMFEHH_01394	4.33e-235	-	2.7.1.221	-	S	ko:K07102	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Phosphotransferase enzyme family
IGHMFEHH_01395	0.0	-	-	-	T	-	-	-	Chase2 domain
IGHMFEHH_01396	2.34e-107	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Low molecular weight phosphatase family
IGHMFEHH_01397	2.7e-113	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
IGHMFEHH_01398	0.0	-	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome bd terminal oxidase subunit I
IGHMFEHH_01399	1.48e-245	-	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome bd terminal oxidase subunit II
IGHMFEHH_01400	0.0	-	1.2.4.2	-	C	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	2-oxoglutarate dehydrogenase C-terminal
IGHMFEHH_01401	6.95e-228	-	2.3.1.61	-	C	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	2-oxoacid dehydrogenases acyltransferase (catalytic domain)
IGHMFEHH_01402	1.61e-115	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
IGHMFEHH_01403	0.0	-	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
IGHMFEHH_01404	1.63e-313	-	3.5.4.28, 3.5.4.31	-	F	ko:K12960	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Amidohydrolase family
IGHMFEHH_01405	3.16e-158	-	-	-	M	ko:K16079	-	ko00000,ko02000	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
IGHMFEHH_01406	0.0	-	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Glycosyl hydrolases family 35
IGHMFEHH_01407	0.0	-	-	-	E	ko:K13893	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
IGHMFEHH_01409	0.0	-	-	-	H	ko:K02014	-	ko00000,ko02000	TonB dependent receptor
IGHMFEHH_01410	0.0	cobQ	-	-	H	-	-	-	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
IGHMFEHH_01411	5.9e-233	cobD	6.3.1.10	-	H	ko:K02227	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
IGHMFEHH_01412	1.99e-239	cobT	2.4.2.21	-	H	ko:K00768	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
IGHMFEHH_01413	6.59e-172	cobS	2.7.8.26	-	H	ko:K02233	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
IGHMFEHH_01414	6.74e-207	-	-	-	G	-	-	-	myo-inosose-2 dehydratase activity
IGHMFEHH_01415	1.82e-126	cobU	2.7.1.156, 2.7.7.62, 6.3.5.10	-	H	ko:K02231,ko:K02232	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	cobinamide kinase activity
IGHMFEHH_01416	0.0	-	-	-	L	-	-	-	Type III restriction enzyme res subunit
IGHMFEHH_01417	0.0	-	3.1.21.4	-	L	ko:K01155	-	ko00000,ko01000,ko02048	Type III restriction enzyme res subunit
IGHMFEHH_01418	8.79e-263	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
IGHMFEHH_01422	3.61e-268	-	-	-	K	-	-	-	Periplasmic binding protein-like domain
IGHMFEHH_01423	8.21e-215	-	-	-	M	-	-	-	Carbohydrate esterase, sialic acid-specific acetylesterase
IGHMFEHH_01424	1.57e-300	-	2.7.1.11, 2.7.1.90	-	H	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions
IGHMFEHH_01426	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	PFAM Glycoside hydrolase, family 20, catalytic core
IGHMFEHH_01427	0.0	rarA	-	-	L	ko:K07478	-	ko00000	MgsA AAA+ ATPase C terminal
IGHMFEHH_01428	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase activity
IGHMFEHH_01429	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Beta galactosidase small chain
IGHMFEHH_01430	1.61e-184	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
IGHMFEHH_01431	1.65e-268	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
IGHMFEHH_01432	0.0	-	4.1.1.19	-	E	ko:K01585	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Pyridoxal-dependent decarboxylase, pyridoxal binding domain
IGHMFEHH_01433	7.45e-301	-	4.1.1.96	-	E	ko:K13747	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	Pyridoxal-dependent decarboxylase, C-terminal sheet domain
IGHMFEHH_01435	0.0	-	-	-	P	-	-	-	Sulfatase
IGHMFEHH_01436	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Leucyl-tRNA synthetase, Domain 2
IGHMFEHH_01437	2.22e-151	-	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribulose-phosphate 3 epimerase family
IGHMFEHH_01438	3.25e-223	-	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Phosphatidylserine decarboxylase
IGHMFEHH_01441	0.0	-	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Thiamine pyrophosphate enzyme, central domain
IGHMFEHH_01442	5.74e-142	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
IGHMFEHH_01443	2.34e-43	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S20
IGHMFEHH_01445	1.31e-289	-	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	LytB protein
IGHMFEHH_01446	8.69e-261	-	-	-	J	ko:K05541	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IGHMFEHH_01447	2.94e-285	-	-	-	E	-	-	-	Transglutaminase-like superfamily
IGHMFEHH_01448	2.62e-202	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
IGHMFEHH_01449	2.91e-182	-	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
IGHMFEHH_01450	7.21e-203	folD	1.5.1.5, 3.5.4.9	-	H	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IGHMFEHH_01451	7.21e-183	-	-	-	S	ko:K09778	-	ko00000	Domain of unknown function (DUF374)
IGHMFEHH_01452	0.0	-	-	-	-	-	-	-	-
IGHMFEHH_01453	0.0	-	-	-	NU	ko:K02453	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02044	Bacterial type II and III secretion system protein
IGHMFEHH_01454	0.0	-	-	-	G	-	-	-	Alpha amylase, catalytic domain
IGHMFEHH_01455	0.0	-	2.7.7.19	-	J	ko:K00970	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Poly A polymerase head domain
IGHMFEHH_01456	8.91e-307	-	-	-	O	-	-	-	peroxiredoxin activity
IGHMFEHH_01457	0.0	-	-	-	P	ko:K03306	-	ko00000	phosphate transporter
IGHMFEHH_01458	0.0	-	3.6.4.13	-	L	ko:K03579	-	ko00000,ko01000	ATP-dependent helicase C-terminal
IGHMFEHH_01459	1.34e-214	-	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Cytidylyltransferase family
IGHMFEHH_01460	0.0	-	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	tail specific protease
IGHMFEHH_01461	0.0	-	-	-	E	-	-	-	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IGHMFEHH_01464	2.15e-186	-	3.4.13.22	-	M	ko:K08641	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-ala-D-ala dipeptidase
IGHMFEHH_01465	0.0	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
IGHMFEHH_01466	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
IGHMFEHH_01467	0.0	-	-	-	-	ko:K07403	-	ko00000	-
IGHMFEHH_01468	0.0	-	2.8.4.4	-	J	ko:K14441	-	ko00000,ko01000,ko03009	Uncharacterized protein family UPF0004
IGHMFEHH_01470	0.0	-	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	4-alpha-glucanotransferase
IGHMFEHH_01471	1.71e-203	-	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase (PrmA)
IGHMFEHH_01472	1.03e-139	-	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Lumazine binding domain
IGHMFEHH_01473	0.0	-	-	-	P	-	-	-	Putative Na+/H+ antiporter
IGHMFEHH_01474	0.0	-	-	-	G	-	-	-	Polysaccharide deacetylase
IGHMFEHH_01476	4.39e-307	nuoD	1.6.5.3	-	C	ko:K00333	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IGHMFEHH_01477	2.88e-142	-	1.6.5.3	-	C	ko:K00334	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Thioredoxin-like [2Fe-2S] ferredoxin
IGHMFEHH_01478	0.0	-	1.6.5.3	-	C	ko:K00335	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region
IGHMFEHH_01479	0.0	-	1.6.5.3	-	C	ko:K00336	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region
IGHMFEHH_01480	1.04e-309	nuoH	1.6.5.3	-	C	ko:K00337	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
IGHMFEHH_01481	1.8e-124	nuoI	1.6.5.3	-	C	ko:K00338	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IGHMFEHH_01482	7.62e-157	-	1.6.5.3	-	C	ko:K00339	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NADH-ubiquinone/plastoquinone oxidoreductase chain 6
IGHMFEHH_01483	6.01e-61	nuoK	1.6.5.3	-	C	ko:K00340	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IGHMFEHH_01484	0.0	-	1.6.5.3	-	CP	ko:K00341	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus
IGHMFEHH_01485	0.0	-	1.6.5.3	-	C	ko:K00342	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Proton-conducting membrane transporter
IGHMFEHH_01486	0.0	nuoN	1.6.5.3	-	C	ko:K00343	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IGHMFEHH_01487	2.99e-217	-	-	-	E	-	-	-	Domain of unknown function (DUF3472)
IGHMFEHH_01489	2.59e-107	-	-	-	-	-	-	-	-
IGHMFEHH_01490	2.39e-126	-	-	-	S	-	-	-	Pfam:DUF59
IGHMFEHH_01491	0.0	-	5.2.1.8	-	O	ko:K03770	-	ko00000,ko01000,ko03110	PPIC-type PPIASE domain
IGHMFEHH_01492	0.0	-	-	-	E	ko:K03305	-	ko00000	POT family
IGHMFEHH_01493	3.06e-238	-	2.5.1.90	-	H	ko:K02523	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Polyprenyl synthetase
IGHMFEHH_01494	1.74e-293	larC	4.99.1.12	-	S	ko:K09121	-	ko00000,ko01000	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
IGHMFEHH_01495	2.69e-188	-	-	-	L	ko:K06864	-	ko00000	tRNA processing
IGHMFEHH_01496	3.1e-168	-	-	-	S	ko:K06898	-	ko00000	AIR carboxylase
IGHMFEHH_01497	0.0	-	-	-	S	-	-	-	Glycosyl hydrolase-like 10
IGHMFEHH_01498	1.74e-157	-	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	Iron/manganese superoxide dismutases, alpha-hairpin domain
IGHMFEHH_01499	5.15e-271	-	-	-	IM	-	-	-	Cytidylyltransferase-like
IGHMFEHH_01500	0.0	murJ	-	-	S	ko:K03980	-	ko00000,ko01011,ko02000	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
IGHMFEHH_01501	3.86e-281	-	2.6.1.1	-	E	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	DegT/DnrJ/EryC1/StrS aminotransferase family
IGHMFEHH_01502	2.83e-110	-	-	-	S	-	-	-	Control of competence regulator ComK, YlbF/YmcA
IGHMFEHH_01503	2.09e-244	-	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IGHMFEHH_01504	0.0	-	-	-	NU	ko:K02652	-	ko00000,ko02035,ko02044	Type II/IV secretion system protein
IGHMFEHH_01505	0.0	-	-	-	NU	ko:K02652	-	ko00000,ko02035,ko02044	Type II secretion system (T2SS), protein E, N-terminal domain
IGHMFEHH_01506	7.26e-285	-	-	-	NU	ko:K02653	-	ko00000,ko02035,ko02044	Type II secretion system (T2SS), protein F
IGHMFEHH_01507	1.34e-07	-	-	-	NU	-	-	-	Prokaryotic N-terminal methylation motif
IGHMFEHH_01508	4.12e-225	-	-	-	M	-	-	-	Glycosyl transferase family 2
IGHMFEHH_01509	8.2e-209	-	-	-	S	-	-	-	Glycosyltransferase like family 2
IGHMFEHH_01510	1.3e-104	-	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	NDK
IGHMFEHH_01511	1.07e-188	-	-	-	-	-	-	-	-
IGHMFEHH_01512	8.28e-135	-	5.4.99.20	-	J	ko:K06181	-	ko00000,ko01000,ko03009	RNA pseudouridylate synthase
IGHMFEHH_01513	1.5e-44	-	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	RNA polymerase activity
IGHMFEHH_01514	6.68e-103	smpB	-	-	O	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
IGHMFEHH_01515	4.12e-139	-	-	-	L	-	-	-	RNase_H superfamily
IGHMFEHH_01516	3.86e-112	-	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
IGHMFEHH_01517	4.28e-274	-	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Citrate synthase, C-terminal domain
IGHMFEHH_01518	9.76e-153	-	-	-	O	-	-	-	Glycoprotease family
IGHMFEHH_01519	3.09e-214	-	-	-	-	-	-	-	-
IGHMFEHH_01522	2.89e-123	-	2.1.1.63	-	L	ko:K00567	-	ko00000,ko01000,ko03400	6-O-methylguanine DNA methyltransferase, DNA binding domain
IGHMFEHH_01524	1.94e-289	-	-	-	C	-	-	-	Iron-containing alcohol dehydrogenase
IGHMFEHH_01525	0.0	-	-	-	S	-	-	-	Alpha-2-macroglobulin family
IGHMFEHH_01526	2.63e-212	MA20_36650	-	-	EG	-	-	-	spore germination
IGHMFEHH_01527	0.0	-	-	-	L	-	-	-	PD-(D/E)XK nuclease superfamily
IGHMFEHH_01528	0.0	-	-	-	L	-	-	-	UvrD/REP helicase N-terminal domain
IGHMFEHH_01531	0.0	-	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	Peptidase family M50
IGHMFEHH_01532	6.39e-80	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IGHMFEHH_01533	2.91e-38	-	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L35
IGHMFEHH_01534	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
IGHMFEHH_01538	7.13e-276	-	-	-	G	-	-	-	Major Facilitator Superfamily
IGHMFEHH_01539	4.51e-84	nuoA	1.6.5.3	-	C	ko:K00330	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IGHMFEHH_01541	3.39e-198	supH	-	-	Q	-	-	-	phosphatase activity
IGHMFEHH_01542	0.0	legA	3.5.1.2	-	G	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	response to abiotic stimulus
IGHMFEHH_01543	0.0	-	-	-	EG	-	-	-	BNR repeat-like domain
IGHMFEHH_01544	4.49e-187	-	-	-	E	-	-	-	PFAM lipolytic protein G-D-S-L family
IGHMFEHH_01545	1.83e-185	-	-	-	E	-	-	-	PFAM lipolytic protein G-D-S-L family
IGHMFEHH_01546	0.0	-	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
IGHMFEHH_01547	1.35e-191	-	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	4Fe-4S single cluster domain
IGHMFEHH_01548	0.0	-	2.3.1.241	-	M	ko:K02517	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Glycosyltransferase family 9 (heptosyltransferase)
IGHMFEHH_01549	2.53e-62	-	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L36
IGHMFEHH_01550	7.92e-294	-	2.3.1.31	-	E	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko01000	alpha/beta hydrolase fold
IGHMFEHH_01551	1.35e-92	-	-	-	O	-	-	-	response to oxidative stress
IGHMFEHH_01552	0.0	-	-	-	T	-	-	-	pathogenesis
IGHMFEHH_01553	9.44e-189	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
IGHMFEHH_01554	1.53e-288	-	4.2.1.20	-	E	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
IGHMFEHH_01555	2.94e-155	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	N-(5'phosphoribosyl)anthranilate (PRA) isomerase
IGHMFEHH_01556	1.67e-177	-	4.1.1.48	-	E	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Indole-3-glycerol phosphate synthase
IGHMFEHH_01557	0.0	trpD	2.4.2.18, 4.1.3.27	-	E	ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IGHMFEHH_01558	0.0	-	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Anthranilate synthase component I, N terminal region
IGHMFEHH_01562	0.0	hppA	3.6.1.1	-	C	ko:K15987	ko00190,map00190	ko00000,ko00001,ko01000	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane
IGHMFEHH_01563	4.94e-245	-	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo/keto reductase family
IGHMFEHH_01564	7.21e-185	-	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Biotin/lipoate A/B protein ligase family
IGHMFEHH_01565	2.55e-247	-	-	-	NU	-	-	-	Prokaryotic N-terminal methylation motif
IGHMFEHH_01566	9.06e-189	-	-	-	-	-	-	-	-
IGHMFEHH_01567	1.38e-174	-	-	-	NU	ko:K02457,ko:K08084	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02044	protein transport across the cell outer membrane
IGHMFEHH_01568	0.0	res	3.1.21.5	-	L	ko:K01156	-	ko00000,ko01000,ko02048	Type III restriction enzyme, res subunit
IGHMFEHH_01569	0.0	-	2.1.1.72	-	L	ko:K07316	-	ko00000,ko01000,ko02048	PFAM DNA methylase N-4 N-6 domain protein
IGHMFEHH_01570	4.88e-133	-	-	-	S	-	-	-	Domain of unknown function (DUF4391)
IGHMFEHH_01571	0.0	-	-	-	L	-	-	-	SNF2 family N-terminal domain
IGHMFEHH_01572	2.01e-243	-	-	-	S	-	-	-	Endonuclease/Exonuclease/phosphatase family
IGHMFEHH_01573	6.91e-165	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70 region 2
IGHMFEHH_01574	0.0	-	-	-	KT	-	-	-	Sigma factor PP2C-like phosphatases
IGHMFEHH_01575	7.28e-269	-	-	-	EGP	-	-	-	Major facilitator Superfamily
IGHMFEHH_01576	0.0	-	-	-	M	-	-	-	Peptidase M60-like family
IGHMFEHH_01577	5.16e-215	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
IGHMFEHH_01578	6.17e-303	-	-	-	M	-	-	-	OmpA family
IGHMFEHH_01579	3.63e-270	-	-	-	E	-	-	-	serine-type peptidase activity
IGHMFEHH_01580	3.06e-286	-	-	-	S	ko:K11720	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Predicted permease YjgP/YjgQ family
IGHMFEHH_01581	1.29e-166	-	-	-	S	-	-	-	HAD-hyrolase-like
IGHMFEHH_01583	2.55e-216	-	2.3.1.39	-	I	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Acyl transferase domain
IGHMFEHH_01584	4.19e-87	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
IGHMFEHH_01585	2.95e-262	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IGHMFEHH_01586	2.38e-258	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Possible lysine decarboxylase
IGHMFEHH_01587	7.69e-277	-	3.4.23.43	-	NOU	ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	Type IV leader peptidase family
IGHMFEHH_01589	0.0	secD	-	-	U	ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IGHMFEHH_01590	9.72e-227	-	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
IGHMFEHH_01591	7.74e-174	-	-	-	T	-	-	-	Outer membrane lipoprotein-sorting protein
IGHMFEHH_01592	3.17e-166	-	-	-	S	ko:K05810	-	ko00000,ko01000	Multi-copper polyphenol oxidoreductase laccase
IGHMFEHH_01593	1.12e-217	-	-	-	-	-	-	-	-
IGHMFEHH_01595	1.56e-169	-	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Type I 3-dehydroquinase
IGHMFEHH_01596	3.1e-217	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
IGHMFEHH_01599	7.58e-209	-	-	-	J	ko:K01894	-	ko00000,ko01000,ko01007,ko03016	tRNA synthetases class I (E and Q), catalytic domain
IGHMFEHH_01600	0.0	-	-	-	P	-	-	-	Citrate transporter
IGHMFEHH_01601	4.39e-145	-	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase homologues.
IGHMFEHH_01602	2.47e-194	-	-	-	S	-	-	-	Domain of unknown function (DUF1732)
IGHMFEHH_01603	0.0	-	2.6.1.66	-	E	ko:K00835	ko00290,ko01100,ko01110,ko01130,map00290,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko01007	Aminotransferase class I and II
IGHMFEHH_01606	8.72e-235	-	-	-	CO	-	-	-	Protein of unknown function, DUF255
IGHMFEHH_01607	6.18e-173	zupT	-	-	P	ko:K07238	-	ko00000,ko02000	transporter
IGHMFEHH_01608	3.04e-258	-	-	-	L	-	-	-	Membrane
IGHMFEHH_01609	5.43e-255	-	2.7.1.11, 2.7.1.90	-	G	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Phosphofructokinase
IGHMFEHH_01610	3.37e-224	-	-	-	M	-	-	-	D-alanyl-D-alanine carboxypeptidase
IGHMFEHH_01613	8.87e-212	-	1.1.1.262	-	H	ko:K00097	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Pyridoxal phosphate biosynthetic protein PdxA
IGHMFEHH_01614	1.56e-60	-	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Ribosomal protein S6
IGHMFEHH_01615	2.54e-145	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IGHMFEHH_01616	8.54e-141	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Imidazoleglycerol-phosphate dehydratase
IGHMFEHH_01618	2.5e-131	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
IGHMFEHH_01619	4.58e-220	prs	2.7.6.1	-	EF	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IGHMFEHH_01620	9.76e-229	-	-	-	C	-	-	-	Transmembrane exosortase (Exosortase_EpsH)
IGHMFEHH_01621	1.29e-175	-	-	-	S	-	-	-	Protein of unknown function (DUF3485)
IGHMFEHH_01622	2.07e-167	pks6	-	-	Q	-	-	-	amino acid activation for nonribosomal peptide biosynthetic process
IGHMFEHH_01623	6.29e-151	-	-	-	-	-	-	-	-
IGHMFEHH_01624	0.0	-	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
IGHMFEHH_01625	0.0	-	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Peptidase S24-like
IGHMFEHH_01626	1.02e-228	-	2.5.1.32, 2.5.1.99	-	I	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Squalene/phytoene synthase
IGHMFEHH_01627	0.0	-	-	-	M	-	-	-	Parallel beta-helix repeats
IGHMFEHH_01628	2.96e-242	-	3.1.3.18	-	F	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD-hyrolase-like
IGHMFEHH_01629	3.02e-172	-	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
IGHMFEHH_01630	3.44e-262	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
IGHMFEHH_01631	1.72e-116	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IGHMFEHH_01632	5.19e-60	-	-	-	S	ko:K09131	-	ko00000	DUF167
IGHMFEHH_01633	9.08e-176	-	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidine biosynthesis protein
IGHMFEHH_01635	1.73e-249	-	-	-	-	-	-	-	-
IGHMFEHH_01636	3.28e-126	-	-	-	M	-	-	-	Polymer-forming cytoskeletal
IGHMFEHH_01637	1.7e-148	-	-	-	M	-	-	-	Polymer-forming cytoskeletal
IGHMFEHH_01638	0.0	-	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	ATPases associated with a variety of cellular activities
IGHMFEHH_01640	7.7e-31	-	-	-	S	ko:K07126	-	ko00000	Sel1-like repeats.
IGHMFEHH_01641	1.44e-110	-	-	-	S	-	-	-	Putative zinc- or iron-chelating domain
IGHMFEHH_01642	6.48e-306	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IGHMFEHH_01643	5.01e-254	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Semialdehyde dehydrogenase, NAD binding domain
IGHMFEHH_01645	0.0	-	-	-	ET	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
IGHMFEHH_01646	1.25e-166	-	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
IGHMFEHH_01647	4.37e-124	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	adenylate kinase activity
IGHMFEHH_01648	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
IGHMFEHH_01649	3.17e-171	-	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	RNA pseudouridylate synthase
IGHMFEHH_01650	1.07e-192	-	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	RNA pseudouridylate synthase
IGHMFEHH_01651	6.93e-154	-	1.5.1.34	-	C	ko:K10679	ko00633,ko01120,map00633,map01120	ko00000,ko00001,ko01000	Nitroreductase family
IGHMFEHH_01652	0.0	-	-	-	M	ko:K04744	-	ko00000,ko02000	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
IGHMFEHH_01653	0.0	-	-	-	M	-	-	-	NPCBM/NEW2 domain
IGHMFEHH_01654	0.0	-	-	-	G	-	-	-	Glycogen debranching enzyme
IGHMFEHH_01655	1.83e-231	-	1.1.1.37	-	C	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible oxidation of malate to oxaloacetate
IGHMFEHH_01656	0.0	-	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	UDP binding domain
IGHMFEHH_01660	1.33e-100	-	-	-	MP	-	-	-	regulation of cell-substrate adhesion
IGHMFEHH_01664	2.59e-75	-	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
IGHMFEHH_01665	1.65e-241	tilS	6.3.4.19	-	D	ko:K04075	-	ko00000,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
IGHMFEHH_01666	1.63e-258	-	2.3.1.8	-	C	ko:K00625	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Phosphate acetyl/butaryl transferase
IGHMFEHH_01667	5.56e-214	-	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	PHP domain
IGHMFEHH_01669	4.48e-231	-	-	-	S	-	-	-	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
IGHMFEHH_01670	0.0	-	-	-	G	-	-	-	Major Facilitator Superfamily
IGHMFEHH_01671	3.64e-293	-	-	-	-	-	-	-	-
IGHMFEHH_01672	0.0	-	-	-	L	-	-	-	TRCF
IGHMFEHH_01673	0.0	-	-	-	S	ko:K07126	-	ko00000	beta-lactamase activity
IGHMFEHH_01674	0.0	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	myo-inosose-2 dehydratase activity
IGHMFEHH_01675	1.58e-24	-	-	-	M	-	-	-	self proteolysis
IGHMFEHH_01677	2.1e-16	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
IGHMFEHH_01681	1.93e-21	-	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	HMGL-like
IGHMFEHH_01682	0.0	-	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	DHHA1 domain
IGHMFEHH_01683	0.0	hyl	2.3.1.48, 3.2.1.169, 3.2.1.35	GH84	G	ko:K01197,ko:K15719	ko00531,ko01100,ko04931,map00531,map01100,map04931	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	beta-N-acetylhexosaminidase activity
IGHMFEHH_01684	8.35e-229	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Zinc-uptake complex component A periplasmic
IGHMFEHH_01685	2.03e-100	-	-	-	-	-	-	-	-
IGHMFEHH_01686	8.77e-192	-	-	-	P	ko:K09820	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
IGHMFEHH_01687	3.84e-180	-	-	-	P	ko:K09819	-	ko00000,ko00002,ko02000	FecCD transport family
IGHMFEHH_01688	5.46e-126	-	-	-	S	ko:K19411	-	ko00000	UvrB/uvrC motif
IGHMFEHH_01689	8.21e-246	-	2.7.14.1	-	E	ko:K19405	-	ko00000,ko01000	ATP:guanido phosphotransferase, C-terminal catalytic domain
IGHMFEHH_01690	0.0	-	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	C-terminal, D2-small domain, of ClpB protein
IGHMFEHH_01691	0.0	-	3.2.1.50	-	G	ko:K01205	ko00531,ko01100,ko04142,map00531,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko04147	Alpha-L-fucosidase
IGHMFEHH_01692	1.42e-74	-	-	-	P	ko:K03972	-	ko00000	Rhodanese Homology Domain
IGHMFEHH_01693	3.24e-205	-	-	-	Q	-	-	-	Fumarylacetoacetate (FAA) hydrolase family
IGHMFEHH_01694	0.0	-	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	HMGL-like
IGHMFEHH_01695	2.57e-223	-	-	-	CO	-	-	-	amine dehydrogenase activity
IGHMFEHH_01696	8.39e-89	-	-	-	S	ko:K09117	-	ko00000	Yqey-like protein
IGHMFEHH_01697	6.13e-165	-	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
IGHMFEHH_01698	2.42e-202	-	-	-	GM	-	-	-	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IGHMFEHH_01699	1.61e-109	-	-	-	M	-	-	-	Dolichyl-phosphate-mannose-protein mannosyltransferase
IGHMFEHH_01700	1.02e-233	-	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class I (W and Y)
IGHMFEHH_01701	1.56e-103	-	-	-	T	-	-	-	Universal stress protein family
IGHMFEHH_01702	4.15e-190	-	-	-	S	ko:K09769	-	ko00000	YmdB-like protein
IGHMFEHH_01703	5.86e-184	-	-	-	H	ko:K22132	-	ko00000,ko03016	ThiF family
IGHMFEHH_01704	3.45e-121	-	-	-	-	-	-	-	-
IGHMFEHH_01706	5.78e-232	-	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
IGHMFEHH_01707	3.09e-122	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
IGHMFEHH_01708	1.53e-288	kbl	2.3.1.29	-	E	ko:K00639	ko00260,map00260	ko00000,ko00001,ko01000,ko01007	Aminotransferase class I and II
IGHMFEHH_01709	0.0	-	-	-	KLT	-	-	-	Sulfatase-modifying factor enzyme 1
IGHMFEHH_01710	1.06e-182	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	AAA domain
IGHMFEHH_01711	0.0	-	-	-	S	ko:K07126	-	ko00000	beta-lactamase activity
IGHMFEHH_01718	4.23e-54	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	thiamine diphosphate biosynthetic process
IGHMFEHH_01719	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IGHMFEHH_01720	0.0	-	-	-	M	ko:K02847,ko:K13009,ko:K16705	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	-O-antigen
IGHMFEHH_01721	8.67e-85	-	-	-	S	-	-	-	Protein of unknown function, DUF488
IGHMFEHH_01722	1.2e-234	-	2.5.1.61	-	H	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Porphobilinogen deaminase, dipyromethane cofactor binding domain
IGHMFEHH_01723	4.9e-241	hemA	1.2.1.70	-	H	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Glutamyl-tRNAGlu reductase, N-terminal domain
IGHMFEHH_01724	1.68e-177	-	-	-	S	-	-	-	Cytochrome C assembly protein
IGHMFEHH_01725	3.84e-189	folE2	3.5.4.16	-	S	ko:K09007	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Type I GTP cyclohydrolase folE2
IGHMFEHH_01726	8.46e-50	-	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S18
IGHMFEHH_01727	5.67e-33	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L33
IGHMFEHH_01728	1.46e-118	-	-	-	T	-	-	-	Prokaryotic dksA/traR C4-type zinc finger
IGHMFEHH_01729	5.9e-232	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
IGHMFEHH_01730	2.86e-245	sun	2.1.1.176, 2.1.1.178	-	J	ko:K03500,ko:K11392	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IGHMFEHH_01731	2.64e-124	-	-	-	S	ko:K07095	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
IGHMFEHH_01732	5.75e-98	nudI	3.6.1.55	-	F	ko:K03574,ko:K12944	-	ko00000,ko01000,ko03400	GDP-mannose mannosyl hydrolase activity
IGHMFEHH_01734	2.88e-283	-	-	-	M	ko:K02005	-	ko00000	HlyD family secretion protein
IGHMFEHH_01735	2.12e-162	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IGHMFEHH_01736	3.42e-313	-	-	-	V	-	-	-	MacB-like periplasmic core domain
IGHMFEHH_01737	9.1e-317	-	-	-	MU	-	-	-	Outer membrane efflux protein
IGHMFEHH_01738	1.57e-284	-	-	-	V	-	-	-	Beta-lactamase
IGHMFEHH_01743	7.74e-121	-	-	-	L	-	-	-	Transposase and inactivated derivatives
IGHMFEHH_01744	2.93e-164	-	-	-	S	-	-	-	Uncharacterised protein family UPF0066
IGHMFEHH_01745	1.07e-303	-	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Dihydro-orotase-like
IGHMFEHH_01746	1.55e-222	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain
IGHMFEHH_01747	1.15e-122	-	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Phosphoribosyl transferase domain
IGHMFEHH_01748	3.73e-90	-	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	AIR carboxylase
IGHMFEHH_01750	0.0	-	-	-	H	ko:K07137	-	ko00000	5-formyltetrahydrofolate cyclo-ligase activity
IGHMFEHH_01751	1.07e-266	-	3.5.3.12	-	E	ko:K10536	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	Porphyromonas-type peptidyl-arginine deiminase
IGHMFEHH_01752	2.11e-89	-	-	-	-	-	-	-	-
IGHMFEHH_01753	0.0	rseP	3.4.21.116	-	M	ko:K06399,ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	metalloendopeptidase activity
IGHMFEHH_01754	2.26e-302	-	-	-	S	-	-	-	AI-2E family transporter
IGHMFEHH_01755	0.0	-	-	-	P	-	-	-	Domain of unknown function
IGHMFEHH_01757	1.6e-111	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
IGHMFEHH_01758	1.12e-312	-	-	-	G	-	-	-	cellulose 1,4-beta-cellobiosidase activity
IGHMFEHH_01759	4.02e-188	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
IGHMFEHH_01761	1.83e-74	-	-	-	-	-	-	-	-
IGHMFEHH_01762	0.0	-	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	DNA Topoisomerase IV
IGHMFEHH_01764	5.26e-132	-	-	-	S	-	-	-	Glycosyl hydrolase 108
IGHMFEHH_01767	8.71e-201	-	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	ParB-like nuclease domain
IGHMFEHH_01768	2.06e-234	-	-	-	S	-	-	-	Peptidase family M28
IGHMFEHH_01769	0.0	-	-	-	M	-	-	-	Aerotolerance regulator N-terminal
IGHMFEHH_01770	0.0	-	-	-	S	-	-	-	Large extracellular alpha-helical protein
IGHMFEHH_01773	2.23e-235	-	-	-	S	ko:K14347	-	ko00000,ko02000,ko04147	SBF-like CPA transporter family (DUF4137)
IGHMFEHH_01774	2.26e-273	-	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	tRNA synthetases class I (W and Y)
IGHMFEHH_01775	6.05e-86	-	-	-	S	ko:K09922	-	ko00000	Putative member of DMT superfamily (DUF486)
IGHMFEHH_01776	2.54e-210	-	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	N-terminal TM domain of oligopeptide transport permease C
IGHMFEHH_01777	3.23e-217	-	-	-	EP	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IGHMFEHH_01778	0.0	-	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
IGHMFEHH_01779	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
IGHMFEHH_01780	1.53e-219	-	-	-	O	-	-	-	Thioredoxin-like domain
IGHMFEHH_01781	1.86e-310	-	1.5.1.7	-	E	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Saccharopine dehydrogenase C-terminal domain
IGHMFEHH_01782	2.48e-235	-	-	-	S	ko:K01128	-	ko00000,ko01000	acid phosphatase activity
IGHMFEHH_01785	0.0	-	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Tubulin/FtsZ family, GTPase domain
IGHMFEHH_01786	3.38e-294	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
IGHMFEHH_01787	1.72e-147	-	-	-	M	-	-	-	NLP P60 protein
IGHMFEHH_01788	0.0	-	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III
IGHMFEHH_01789	0.0	-	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter transmembrane region
IGHMFEHH_01790	0.0	-	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter transmembrane region
IGHMFEHH_01791	0.0	-	-	-	H	-	-	-	NAD synthase
IGHMFEHH_01792	1.49e-167	-	-	-	Q	ko:K02066	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Permease MlaE
IGHMFEHH_01793	7.14e-189	-	-	-	Q	ko:K02065	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
IGHMFEHH_01794	2.21e-230	-	-	-	Q	ko:K02067	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	MlaD protein
IGHMFEHH_01795	2.69e-38	-	-	-	T	-	-	-	ribosome binding
IGHMFEHH_01801	2.84e-149	-	-	-	M	-	-	-	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
IGHMFEHH_01802	5.88e-229	-	-	-	L	-	-	-	Transposase zinc-ribbon domain
IGHMFEHH_01803	5.1e-265	-	-	-	NU	ko:K02669	-	ko00000,ko02035,ko02044	Type II/IV secretion system protein
IGHMFEHH_01804	9.11e-261	-	-	-	NU	ko:K02669	-	ko00000,ko02035,ko02044	Type II/IV secretion system protein
IGHMFEHH_01805	1.37e-247	ppiD	5.2.1.8	-	O	ko:K03769,ko:K03770,ko:K03771,ko:K07533	-	ko00000,ko01000,ko03110	peptidyl-prolyl cis-trans isomerase activity
IGHMFEHH_01807	0.0	-	-	-	-	-	-	-	-
IGHMFEHH_01808	9.79e-180	kdsB	2.7.7.38	-	M	ko:K00979	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
IGHMFEHH_01809	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
IGHMFEHH_01810	0.0	-	-	-	E	-	-	-	Sodium:solute symporter family
IGHMFEHH_01813	0.0	-	-	-	M	-	-	-	pathogenesis
IGHMFEHH_01815	3.06e-264	-	-	GT4	M	ko:K16703	-	ko00000,ko01000,ko01003	transferase activity, transferring glycosyl groups
IGHMFEHH_01821	4.42e-147	-	-	-	M	ko:K17733	-	ko00000,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
IGHMFEHH_01824	0.0	-	-	-	P	-	-	-	Cation transport protein
IGHMFEHH_01825	8.29e-299	-	-	-	V	ko:K03327	-	ko00000,ko02000	drug transmembrane transporter activity
IGHMFEHH_01826	7.41e-120	-	-	-	-	-	-	-	-
IGHMFEHH_01827	9.86e-54	-	-	-	-	-	-	-	-
IGHMFEHH_01828	2.93e-102	-	-	-	-	-	-	-	-
IGHMFEHH_01829	0.0	-	2.1.1.182	-	IJ	ko:K02528	-	ko00000,ko01000,ko03009	Ribosomal RNA adenine dimethylases
IGHMFEHH_01830	1.04e-246	-	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	NmrA-like family
IGHMFEHH_01835	1.39e-128	-	-	-	U	ko:K05595	-	ko00000,ko02000	MarC family integral membrane protein
IGHMFEHH_01836	4.88e-177	-	4.2.99.20	-	I	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Alpha/beta hydrolase family
IGHMFEHH_01837	1.46e-75	-	-	-	S	ko:K09954	-	ko00000	Putative quorum-sensing-regulated virulence factor
IGHMFEHH_01839	1.24e-51	-	-	-	-	-	-	-	-
IGHMFEHH_01840	2.33e-132	-	-	-	S	-	-	-	Protein of unknown function (DUF2589)
IGHMFEHH_01841	3.25e-183	-	-	-	-	-	-	-	-
IGHMFEHH_01842	2.59e-174	-	-	-	S	-	-	-	Protein of unknown function (DUF2589)
IGHMFEHH_01843	4.44e-110	-	-	-	KT	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	phosphorelay signal transduction system
IGHMFEHH_01844	4.31e-302	-	-	-	C	-	-	-	4 iron, 4 sulfur cluster binding
IGHMFEHH_01845	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
IGHMFEHH_01846	2.67e-222	-	-	-	K	-	-	-	Transcriptional regulator
IGHMFEHH_01847	8.56e-178	-	-	-	C	-	-	-	aldo keto reductase
IGHMFEHH_01848	9.71e-185	-	-	-	S	-	-	-	Alpha/beta hydrolase family
IGHMFEHH_01849	4.8e-274	-	-	-	S	ko:K06889	-	ko00000	X-Pro dipeptidyl-peptidase (S15 family)
IGHMFEHH_01850	1.26e-304	-	-	-	C	-	-	-	Carboxymuconolactone decarboxylase family
IGHMFEHH_01851	1.2e-158	-	-	-	IQ	-	-	-	Short chain dehydrogenase
IGHMFEHH_01852	1.26e-169	corC_1	-	-	P	ko:K03699	-	ko00000,ko02042	Transporter associated domain
IGHMFEHH_01854	4.21e-137	-	-	-	J	ko:K05808	-	ko00000,ko03009	Sigma 54 modulation/S30EA ribosomal protein C terminus
IGHMFEHH_01856	2.17e-08	-	-	-	M	-	-	-	major outer membrane lipoprotein
IGHMFEHH_01857	0.0	-	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
IGHMFEHH_01859	2.15e-169	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	KR domain
IGHMFEHH_01860	5.51e-308	-	-	-	C	-	-	-	Sulfatase-modifying factor enzyme 1
IGHMFEHH_01861	1.6e-22	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
IGHMFEHH_01862	1.15e-05	-	-	-	-	-	-	-	-
IGHMFEHH_01864	7.45e-49	XK27_09985	-	-	S	-	-	-	Protein of unknown function (DUF1232)
IGHMFEHH_01865	2.77e-192	-	-	-	S	ko:K07051	-	ko00000	TatD related DNase
IGHMFEHH_01866	3e-54	-	-	-	-	-	-	-	-
IGHMFEHH_01867	4.83e-163	-	-	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002	-
IGHMFEHH_01868	0.0	-	1.3.5.1, 1.3.5.4	-	C	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	Fumarate reductase flavoprotein C-term
IGHMFEHH_01869	1.29e-187	-	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	2Fe-2S iron-sulfur cluster binding domain
IGHMFEHH_01879	1.92e-15	-	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Ami_3
IGHMFEHH_01886	1.47e-42	-	-	-	L	ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
IGHMFEHH_01888	4.1e-308	-	-	-	E	ko:K03310	-	ko00000	Sodium:alanine symporter family
IGHMFEHH_01889	2.43e-95	-	-	-	K	-	-	-	-acetyltransferase
IGHMFEHH_01890	8.6e-222	-	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Glutaminase
IGHMFEHH_01891	0.0	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	amino acid
IGHMFEHH_01892	0.0	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
IGHMFEHH_01895	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Prolyl-tRNA synthetase, C-terminal
IGHMFEHH_01896	2.04e-158	-	-	-	S	-	-	-	Peptidase family M50
IGHMFEHH_01898	2.27e-215	-	-	-	JM	-	-	-	Nucleotidyl transferase
IGHMFEHH_01899	2.88e-273	-	-	-	S	-	-	-	Phosphotransferase enzyme family
IGHMFEHH_01900	3.51e-223	-	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	NmrA-like family
IGHMFEHH_01902	0.0	-	-	-	L	ko:K07478	-	ko00000	MgsA AAA+ ATPase C terminal
IGHMFEHH_01903	1.18e-295	-	-	-	-	-	-	-	-
IGHMFEHH_01904	0.0	-	-	-	-	-	-	-	-
IGHMFEHH_01905	1.03e-138	mntP	-	-	P	-	-	-	manganese ion transmembrane transporter activity
IGHMFEHH_01906	1.34e-186	-	-	-	S	-	-	-	Phenazine biosynthesis-like protein
IGHMFEHH_01907	2.83e-177	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
IGHMFEHH_01908	5.36e-316	-	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	Sigma-54 factor, Activator interacting domain (AID)
IGHMFEHH_01909	7.78e-273	ycaD	-	-	EGP	ko:K08219	-	ko00000,ko02000	Major facilitator Superfamily
IGHMFEHH_01910	1.13e-220	-	3.4.11.10, 3.4.11.6	-	DZ	ko:K19701	-	ko00000,ko01000,ko01002	aminopeptidase activity
IGHMFEHH_01911	6.98e-289	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
IGHMFEHH_01912	0.0	-	-	-	S	-	-	-	inositol 2-dehydrogenase activity
IGHMFEHH_01914	5.53e-285	-	3.6.4.13	-	L	ko:K11927	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	helicase superfamily c-terminal domain
IGHMFEHH_01916	4.21e-144	-	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	CDP-alcohol phosphatidyltransferase
IGHMFEHH_01917	0.0	-	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IGHMFEHH_01918	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
IGHMFEHH_01919	8.03e-277	-	4.2.1.51, 5.4.99.5	-	E	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Chorismate mutase type II
IGHMFEHH_01920	3.72e-237	-	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
IGHMFEHH_01921	1.91e-191	-	-	-	S	-	-	-	NIF3 (NGG1p interacting factor 3)
IGHMFEHH_01922	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4340)
IGHMFEHH_01923	0.0	-	-	-	N	-	-	-	ABC-type uncharacterized transport system
IGHMFEHH_01924	2.49e-183	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
IGHMFEHH_01925	1.09e-223	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
IGHMFEHH_01926	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IGHMFEHH_01927	2.38e-133	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	nUDIX hydrolase
IGHMFEHH_01929	2.89e-251	-	2.3.1.1	-	E	ko:K14682	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Acetyltransferase (GNAT) family
IGHMFEHH_01930	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IGHMFEHH_01931	0.0	-	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
IGHMFEHH_01935	3.5e-172	-	6.3.5.11, 6.3.5.9	-	V	ko:K02224,ko:K18554	ko00860,ko01100,ko01120,map00860,map01100,map01120	br01600,ko00000,ko00001,ko01000,ko01504	Chloramphenicol phosphotransferase-like protein
IGHMFEHH_01936	5.31e-82	-	-	-	K	ko:K07343	-	ko00000	positive regulation of type IV pilus biogenesis
IGHMFEHH_01937	5.44e-232	-	-	-	CO	-	-	-	Redoxin
IGHMFEHH_01938	1.73e-123	paiA	-	-	K	-	-	-	acetyltransferase
IGHMFEHH_01939	2.66e-215	-	-	-	K	-	-	-	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen
IGHMFEHH_01941	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl tRNA synthetase N terminal dom
IGHMFEHH_01944	0.0	-	3.4.24.70	-	E	ko:K01414	-	ko00000,ko01000,ko01002	Peptidase family M3
IGHMFEHH_01945	0.0	-	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
IGHMFEHH_01946	2.1e-06	-	-	-	-	-	-	-	-
IGHMFEHH_01947	0.0	-	-	-	G	-	-	-	Glycosyl hydrolases family 18
IGHMFEHH_01948	0.0	-	-	-	S	ko:K07126,ko:K13582	ko04112,map04112	ko00000,ko00001	beta-lactamase activity
IGHMFEHH_01949	1.38e-277	-	6.2.1.26	-	IQ	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	AMP-binding enzyme
IGHMFEHH_01950	1.27e-70	-	-	-	K	-	-	-	ribonuclease III activity
IGHMFEHH_01951	9.38e-166	-	-	-	-	-	-	-	-
IGHMFEHH_01952	8.56e-140	nuoC	1.6.5.3	-	C	ko:K00332	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IGHMFEHH_01953	6.52e-139	nuoB	1.6.5.3	-	C	ko:K00331	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IGHMFEHH_01954	4.29e-256	-	-	-	S	-	-	-	Putative S-adenosyl-L-methionine-dependent methyltransferase
IGHMFEHH_01955	1.96e-226	-	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Quinolinate synthetase A protein
IGHMFEHH_01956	7.6e-303	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IGHMFEHH_01957	0.0	-	3.2.1.52	GH20	G	ko:K01207,ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko01501,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map01501,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycoside hydrolase, family 20, catalytic core
IGHMFEHH_01959	5.11e-106	-	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	6-pyruvoyl tetrahydropterin synthase
IGHMFEHH_01961	0.0	-	4.2.1.2	-	C	ko:K01676	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible hydration of fumarate to (S)- malate
IGHMFEHH_01963	0.0	-	-	-	S	-	-	-	Phosphoadenosine phosphosulfate reductase
IGHMFEHH_01964	3.45e-121	-	-	-	K	-	-	-	ParB domain protein nuclease
IGHMFEHH_01967	9.17e-116	-	-	-	L	-	-	-	Staphylococcal nuclease homologues
IGHMFEHH_01968	1.27e-243	-	-	-	M	-	-	-	Alginate lyase
IGHMFEHH_01969	2.09e-205	-	-	-	IQ	-	-	-	KR domain
IGHMFEHH_01972	7.17e-104	yciA	-	-	I	ko:K10806	ko01040,map01040	ko00000,ko00001,ko01000,ko01004	acyl-coa hydrolase
IGHMFEHH_01973	0.0	hsrA	-	-	EGP	-	-	-	Major facilitator Superfamily
IGHMFEHH_01974	1.41e-289	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
IGHMFEHH_01975	1.96e-241	-	-	-	CH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
IGHMFEHH_01976	5.26e-180	-	-	-	CH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
IGHMFEHH_01977	0.0	-	3.2.1.23	-	G	ko:K01190,ko:K12308	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolases family 35
IGHMFEHH_01978	7.61e-47	-	-	-	T	-	-	-	Tyrosine phosphatase family
IGHMFEHH_01979	8.77e-158	-	-	-	C	-	-	-	Nitroreductase family
IGHMFEHH_01980	0.0	-	-	-	E	-	-	-	Transglutaminase-like
IGHMFEHH_01981	5.58e-110	-	-	-	S	-	-	-	Bacterial transferase hexapeptide (six repeats)
IGHMFEHH_01982	6.56e-112	-	-	-	S	ko:K08999	-	ko00000	Bifunctional nuclease
IGHMFEHH_01984	0.0	-	-	-	P	-	-	-	Citrate transporter
IGHMFEHH_01986	2.3e-257	-	-	-	S	-	-	-	Glycosyltransferase family 10 (fucosyltransferase) C-term
IGHMFEHH_01987	0.0	-	-	-	I	-	-	-	Acyltransferase family
IGHMFEHH_01988	1.49e-252	-	-	-	S	-	-	-	Glycosyltransferase family 10 (fucosyltransferase) C-term
IGHMFEHH_01989	1.44e-309	-	-	-	M	-	-	-	Glycosyl transferases group 1
IGHMFEHH_01990	1.71e-203	-	-	-	-	-	-	-	-
IGHMFEHH_01991	7.85e-288	-	-	-	M	-	-	-	Glycosyltransferase like family 2
IGHMFEHH_01992	2.26e-245	-	5.1.3.20	-	M	ko:K03274	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	3-beta hydroxysteroid dehydrogenase/isomerase family
IGHMFEHH_01993	5.25e-233	-	-	GT9	M	ko:K02843,ko:K02849	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	ADP-heptose-lipopolysaccharide heptosyltransferase activity
IGHMFEHH_01994	5.82e-250	-	-	-	S	-	-	-	Glycosyltransferase like family 2
IGHMFEHH_01995	1.85e-243	-	-	-	H	-	-	-	PFAM glycosyl transferase family 8
IGHMFEHH_01996	1.08e-209	lpxG	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase
IGHMFEHH_01998	8.48e-241	-	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain
IGHMFEHH_01999	9.36e-171	truB	5.4.99.25	-	J	ko:K03177	-	ko00000,ko01000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IGHMFEHH_02000	7.36e-222	-	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin kinase
IGHMFEHH_02001	9e-65	panD	4.1.1.11	-	H	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
IGHMFEHH_02002	3.86e-76	-	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase SecG subunit
IGHMFEHH_02003	1.15e-151	-	-	-	NU	-	-	-	Prokaryotic N-terminal methylation motif
IGHMFEHH_02004	6.87e-256	-	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IGHMFEHH_02005	2.14e-127	-	-	-	-	-	-	-	-
IGHMFEHH_02006	5.05e-233	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
IGHMFEHH_02007	2.89e-173	-	-	-	S	-	-	-	NYN domain
IGHMFEHH_02008	4.52e-153	ppaX_1	3.1.3.18, 3.6.1.1	-	S	ko:K01091,ko:K06019	ko00190,ko00630,ko01100,ko01110,ko01130,map00190,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	glycolate biosynthetic process
IGHMFEHH_02009	1.58e-138	-	-	-	S	-	-	-	Maltose acetyltransferase
IGHMFEHH_02010	2.96e-211	-	-	-	L	-	-	-	EcoRII C terminal
IGHMFEHH_02011	1.17e-212	dcm	2.1.1.37	-	H	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	PFAM C-5 cytosine-specific DNA methylase
IGHMFEHH_02012	0.0	-	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	GMP synthase C terminal domain
IGHMFEHH_02013	0.0	-	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	IMP dehydrogenase / GMP reductase domain
IGHMFEHH_02014	8.71e-120	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Low molecular weight phosphatase family
IGHMFEHH_02015	0.0	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
IGHMFEHH_02017	2.52e-267	-	-	GT4	M	ko:K16703	-	ko00000,ko01000,ko01003	transferase activity, transferring glycosyl groups
IGHMFEHH_02018	1.55e-254	-	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
IGHMFEHH_02019	2.84e-286	-	-	-	S	-	-	-	Phosphotransferase enzyme family
IGHMFEHH_02020	3.23e-253	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IGHMFEHH_02022	7.86e-138	-	-	-	T	-	-	-	histone H2A K63-linked ubiquitination
IGHMFEHH_02023	3.82e-128	-	2.1.1.63	-	L	ko:K00567	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IGHMFEHH_02024	5.11e-222	-	-	-	G	-	-	-	Glycosyl hydrolases family 16
IGHMFEHH_02025	8.55e-214	-	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IGHMFEHH_02026	0.0	-	-	-	T	ko:K06207	-	ko00000	Elongation factor G C-terminus
IGHMFEHH_02027	1.32e-235	-	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
IGHMFEHH_02028	1.38e-313	-	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-dependent decarboxylase, pyridoxal binding domain
IGHMFEHH_02029	6.62e-257	-	-	-	S	ko:K11744	-	ko00000	AI-2E family transporter
IGHMFEHH_02030	8.06e-156	gph	3.1.3.18, 3.6.1.1	-	S	ko:K01091,ko:K06019	ko00190,ko00630,ko01100,ko01110,ko01130,map00190,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	glycolate biosynthetic process
IGHMFEHH_02031	1.39e-295	-	-	-	E	-	-	-	Amino acid permease
IGHMFEHH_02032	2.02e-173	-	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Thiazole biosynthesis protein ThiG
IGHMFEHH_02034	1.79e-201	-	-	-	S	-	-	-	SigmaW regulon antibacterial
IGHMFEHH_02035	3.89e-242	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IGHMFEHH_02037	0.0	-	-	-	P	ko:K03455	-	ko00000	TrkA-N domain
IGHMFEHH_02038	0.0	-	-	-	P	-	-	-	Dimerisation domain of Zinc Transporter
IGHMFEHH_02039	5.84e-173	-	-	-	K	-	-	-	Transcriptional regulator
IGHMFEHH_02040	0.0	-	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IGHMFEHH_02041	2.32e-167	-	4.3.99.3	-	O	ko:K10026	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
IGHMFEHH_02042	3.41e-198	-	2.7.13.3	-	Q	ko:K07777	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Transposase
IGHMFEHH_02043	0.0	-	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
IGHMFEHH_02044	1.55e-313	-	-	-	S	-	-	-	Protein of unknown function (DUF1015)
IGHMFEHH_02045	2.58e-252	-	-	-	E	-	-	-	Aminotransferase class-V
IGHMFEHH_02046	5.45e-234	-	-	-	S	-	-	-	Conserved hypothetical protein 698
IGHMFEHH_02047	3.14e-215	-	-	-	K	-	-	-	LysR substrate binding domain
IGHMFEHH_02050	4.23e-43	-	3.2.1.23	-	M	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
IGHMFEHH_02057	4.27e-188	-	5.2.1.8	-	O	ko:K03773	-	ko00000,ko01000,ko03110	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase
IGHMFEHH_02058	2.18e-138	-	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IGHMFEHH_02059	2.46e-272	-	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	Thermophilic metalloprotease (M29)
IGHMFEHH_02060	2.09e-207	-	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
IGHMFEHH_02061	0.0	-	-	-	P	ko:K03455	-	ko00000	TrkA-N domain
IGHMFEHH_02062	1.2e-167	-	-	-	L	ko:K03424	-	ko00000,ko01000	TatD related DNase
IGHMFEHH_02066	5.26e-23	-	-	-	S	-	-	-	Protein of unknown function (DUF4065)
IGHMFEHH_02068	3.95e-252	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IGHMFEHH_02069	8.2e-214	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
IGHMFEHH_02070	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IGHMFEHH_02071	9.85e-197	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IGHMFEHH_02075	4.33e-161	menG	2.1.1.163, 2.1.1.201	-	Q	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	ubiE/COQ5 methyltransferase family
IGHMFEHH_02076	0.0	-	-	-	V	-	-	-	MatE
IGHMFEHH_02078	0.0	-	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	C-terminal, D2-small domain, of ClpB protein
IGHMFEHH_02080	1.29e-230	-	-	-	K	-	-	-	DNA-binding transcription factor activity
IGHMFEHH_02081	1.76e-79	-	-	-	S	-	-	-	PFAM Cupin 2 conserved barrel domain protein
IGHMFEHH_02082	2.36e-131	-	3.6.3.12	-	P	ko:K01548	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
IGHMFEHH_02083	0.0	-	3.6.3.12	-	P	ko:K01547	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
IGHMFEHH_02084	0.0	-	3.6.3.12	-	P	ko:K01546	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
IGHMFEHH_02086	2.4e-167	-	-	-	T	ko:K07667	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
IGHMFEHH_02087	0.0	-	2.7.13.3	-	T	ko:K07646	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Osmosensitive K+ channel His kinase sensor domain
IGHMFEHH_02090	1.67e-05	-	-	-	-	-	-	-	-
IGHMFEHH_02091	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Beta galactosidase small chain
IGHMFEHH_02092	7.24e-266	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2219)
IGHMFEHH_02093	7.25e-202	-	-	-	L	ko:K03424	-	ko00000,ko01000	TatD related DNase
IGHMFEHH_02094	2.63e-84	-	-	-	M	-	-	-	Lysin motif
IGHMFEHH_02095	3.05e-180	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
IGHMFEHH_02096	0.0	-	-	-	V	-	-	-	MatE
IGHMFEHH_02097	2.47e-251	-	3.3.1.1	-	H	ko:K01251	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	adenosylhomocysteinase activity
IGHMFEHH_02099	1.45e-258	-	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
IGHMFEHH_02101	1.1e-154	-	-	-	M	-	-	-	Bacterial transferase hexapeptide (six repeats)
IGHMFEHH_02102	5.3e-265	-	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	RibD C-terminal domain
IGHMFEHH_02104	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
IGHMFEHH_02105	8.62e-273	-	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III, delta subunit
IGHMFEHH_02107	0.0	-	-	-	O	-	-	-	Trypsin
IGHMFEHH_02108	7.97e-108	-	2.2.1.6	-	E	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	ACT domain
IGHMFEHH_02109	0.0	-	3.6.4.13	-	L	ko:K03578	-	ko00000,ko01000	Oligonucleotide/oligosaccharide-binding (OB)-fold
IGHMFEHH_02110	3.52e-161	-	-	-	P	ko:K03499	-	ko00000,ko02000	TrkA-N domain
IGHMFEHH_02111	0.0	-	-	-	P	-	-	-	Cation transport protein
IGHMFEHH_02113	2.58e-178	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
IGHMFEHH_02114	0.0	-	-	-	G	-	-	-	Domain of unknown function (DUF4091)
IGHMFEHH_02115	3.08e-68	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
IGHMFEHH_02116	1.32e-101	manC	-	-	S	-	-	-	Cupin domain
IGHMFEHH_02117	0.0	-	1.2.7.1	-	C	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
IGHMFEHH_02118	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class II (D, K and N)
IGHMFEHH_02119	1.02e-187	pppL	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	protein serine/threonine phosphatase activity
IGHMFEHH_02120	4.34e-152	-	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Glycerol-3-phosphate acyltransferase
IGHMFEHH_02121	8.08e-236	gpsA	1.1.1.94	-	C	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
IGHMFEHH_02122	8.62e-102	-	-	-	-	-	-	-	-
IGHMFEHH_02124	6.95e-264	pqqE	-	-	C	ko:K06139	-	ko00000	SMART Elongator protein 3 MiaB NifB
IGHMFEHH_02125	5.38e-313	pqqE	-	-	C	ko:K06139	-	ko00000	SMART Elongator protein 3 MiaB NifB
IGHMFEHH_02126	0.0	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Cys/Met metabolism PLP-dependent enzyme
IGHMFEHH_02127	4.94e-05	-	-	-	-	-	-	-	-
IGHMFEHH_02128	0.0	-	-	-	O	ko:K07391	-	ko00000	Magnesium chelatase, subunit ChlI C-terminal
IGHMFEHH_02129	1.21e-210	-	-	-	S	-	-	-	Rhomboid family
IGHMFEHH_02130	1.46e-266	-	-	-	E	-	-	-	FAD dependent oxidoreductase
IGHMFEHH_02131	2.64e-267	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
IGHMFEHH_02133	2.57e-251	-	-	-	S	ko:K11941	-	ko00000,ko01000	transferase activity, transferring acyl groups other than amino-acyl groups
IGHMFEHH_02137	1.7e-260	-	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
IGHMFEHH_02138	8.43e-155	-	1.5.1.34	-	C	ko:K10679	ko00633,ko01120,map00633,map01120	ko00000,ko00001,ko01000	Nitroreductase family
IGHMFEHH_02139	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycosyl hydrolase family 20, domain 2
IGHMFEHH_02140	6.15e-180	-	-	-	M	-	-	-	NLP P60 protein
IGHMFEHH_02141	1.37e-86	-	-	-	S	ko:K09940	-	ko00000	Domain of unknown function (DUF4870)
IGHMFEHH_02143	2.09e-76	-	-	-	C	ko:K04651	-	ko00000,ko03110	Hydrogenase/urease nickel incorporation, metallochaperone, hypA
IGHMFEHH_02144	3.4e-126	-	-	-	C	ko:K03605	-	ko00000,ko01000,ko01002	Hydrogenase maturation protease
IGHMFEHH_02145	3.22e-290	hyaC	-	-	C	ko:K03620	ko02020,map02020	ko00000,ko00001	Prokaryotic cytochrome b561
IGHMFEHH_02146	0.0	-	1.12.99.6	-	C	ko:K06281	ko00633,ko01120,map00633,map01120	ko00000,ko00001,ko01000	Nickel-dependent hydrogenase
IGHMFEHH_02147	2.95e-299	-	1.12.99.6	-	C	ko:K06282	ko00633,ko01120,map00633,map01120	ko00000,ko00001,ko01000	NiFe/NiFeSe hydrogenase small subunit C-terminal
IGHMFEHH_02148	0.0	-	-	-	M	ko:K07267	-	ko00000,ko02000	wide pore channel activity
IGHMFEHH_02150	1.28e-315	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IGHMFEHH_02151	0.0	-	-	-	H	-	-	-	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IGHMFEHH_02152	0.0	-	3.4.24.3	-	NU	ko:K01387	-	ko00000,ko01000,ko01002,ko02042	translation initiation factor activity
IGHMFEHH_02153	0.0	-	-	-	M	-	-	-	Transglycosylase
IGHMFEHH_02154	3.08e-134	-	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	Peptidyl-tRNA hydrolase
IGHMFEHH_02155	1.12e-215	-	-	-	S	-	-	-	Protein of unknown function DUF58
IGHMFEHH_02156	3.82e-231	-	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
IGHMFEHH_02157	1e-215	-	3.5.1.53	-	K	ko:K12251	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
IGHMFEHH_02159	2.84e-103	-	-	-	E	-	-	-	Alcohol dehydrogenase GroES-like domain
IGHMFEHH_02160	8.32e-157	-	-	-	E	-	-	-	Alcohol dehydrogenase GroES-like domain
IGHMFEHH_02161	7.32e-309	-	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Seryl-tRNA synthetase N-terminal domain
IGHMFEHH_02163	5.11e-265	-	-	-	H	-	-	-	Elongator protein 3, MiaB family, Radical SAM
IGHMFEHH_02164	0.0	yidC	-	-	O	ko:K03217,ko:K06872	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	serine-type endopeptidase activity
IGHMFEHH_02165	3.72e-158	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
IGHMFEHH_02166	2.27e-128	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IGHMFEHH_02167	3.55e-257	-	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Glycosyl hydrolase family 3 N terminal domain
IGHMFEHH_02168	4.86e-230	exsH	3.2.1.178, 3.2.1.18, 3.2.1.52	GH16,GH20,GH33	G	ko:K01186,ko:K12373,ko:K20830	ko00511,ko00513,ko00520,ko00531,ko00600,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00600,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko02042,ko03110	xyloglucan:xyloglucosyl transferase activity
IGHMFEHH_02169	0.0	-	-	-	I	ko:K06889,ko:K09914	-	ko00000	PFAM Prenyltransferase squalene oxidase
IGHMFEHH_02170	7.34e-315	-	1.1.1.40	-	C	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Malic enzyme, NAD binding domain
IGHMFEHH_02172	0.0	menD	2.2.1.9	-	H	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
IGHMFEHH_02173	0.0	-	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class I (C) catalytic domain
IGHMFEHH_02174	8.7e-300	-	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase class I and II
IGHMFEHH_02175	1.19e-92	-	5.1.3.29	-	G	ko:K02431	-	ko00000,ko01000	RbsD / FucU transport protein family
IGHMFEHH_02176	7.51e-285	-	-	-	S	-	-	-	very-long-chain-acyl-CoA dehydrogenase activity
IGHMFEHH_02178	0.0	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
IGHMFEHH_02179	2.21e-230	-	-	-	C	-	-	-	Nitroreductase family
IGHMFEHH_02180	0.0	-	-	-	S	-	-	-	polysaccharide biosynthetic process
IGHMFEHH_02181	3.13e-123	-	-	-	C	-	-	-	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IGHMFEHH_02182	1.55e-39	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
IGHMFEHH_02183	1.77e-236	-	-	-	M	-	-	-	Glycosyl transferase, family 2
IGHMFEHH_02184	1.42e-209	-	-	-	M	-	-	-	PFAM glycosyl transferase family 2
IGHMFEHH_02185	4.42e-112	-	-	-	S	ko:K03818	-	ko00000,ko01000	maltose O-acetyltransferase activity
IGHMFEHH_02186	0.0	-	-	-	-	-	-	-	-
IGHMFEHH_02187	3.43e-281	lsgC	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
IGHMFEHH_02188	4.3e-278	-	-	-	M	-	-	-	Glycosyl transferase 4-like domain
IGHMFEHH_02189	1.48e-246	-	-	-	M	-	-	-	Glycosyl transferases group 1
IGHMFEHH_02190	1.03e-199	-	-	-	S	-	-	-	Glycosyl transferase family 11
IGHMFEHH_02191	2.62e-263	-	-	-	M	ko:K02847,ko:K13009	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	-O-antigen
IGHMFEHH_02192	8.48e-242	-	-	-	-	-	-	-	-
IGHMFEHH_02193	6.49e-290	gtf1	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	transferase activity, transferring glycosyl groups
IGHMFEHH_02194	1.41e-285	lsgC	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
IGHMFEHH_02195	2.85e-290	lsgC	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
IGHMFEHH_02196	9.83e-189	wbyL	-	GT2	M	ko:K13002	-	ko00000,ko01000,ko01003,ko01005	transferase activity, transferring glycosyl groups
IGHMFEHH_02197	2.68e-173	-	-	-	M	-	-	-	Bacterial sugar transferase
IGHMFEHH_02198	9.48e-165	-	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	protein tyrosine phosphatase activity
IGHMFEHH_02199	0.0	gumC	-	-	DM	ko:K16554	ko05111,map05111	ko00000,ko00001,ko02000	PFAM lipopolysaccharide biosynthesis protein
IGHMFEHH_02200	4e-180	-	-	-	M	ko:K01991	ko02026,map02026	ko00000,ko00001,ko02000	polysaccharide export