Read a JSON File

ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HPFPGLDM_00002	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Glycosyl hydrolase family 36 N-terminal domain
HPFPGLDM_00003	6.06e-54	himA	-	-	L	ko:K03530,ko:K04764,ko:K05788	-	ko00000,ko03032,ko03036,ko03400	regulation of translation
HPFPGLDM_00004	0.0	-	-	-	-	-	-	-	-
HPFPGLDM_00007	1.15e-303	-	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	tRNA (Uracil-5-)-methyltransferase
HPFPGLDM_00008	0.0	miaB	2.8.4.3	-	J	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HPFPGLDM_00009	0.0	-	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein
HPFPGLDM_00010	3.29e-258	-	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
HPFPGLDM_00011	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
HPFPGLDM_00012	1.47e-204	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HPFPGLDM_00013	1.73e-307	-	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HPFPGLDM_00014	0.0	-	-	-	-	-	-	-	-
HPFPGLDM_00015	1.24e-163	-	-	-	S	-	-	-	SWIM zinc finger
HPFPGLDM_00016	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Argininosuccinate lyase C-terminal
HPFPGLDM_00017	0.0	-	-	-	U	ko:K03321	-	ko00000,ko02000	Sulfate permease family
HPFPGLDM_00018	8.42e-124	-	-	-	-	-	-	-	-
HPFPGLDM_00019	1.04e-109	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HPFPGLDM_00021	0.0	-	-	-	S	-	-	-	Carbohydrate esterase, sialic acid-specific acetylesterase
HPFPGLDM_00023	6e-37	-	-	-	K	-	-	-	sequence-specific DNA binding
HPFPGLDM_00024	3.04e-167	-	-	-	S	-	-	-	Pfam:HipA_N
HPFPGLDM_00025	4.84e-36	-	-	-	S	-	-	-	zeta toxin
HPFPGLDM_00032	2.04e-45	-	-	-	S	-	-	-	Domain of unknown function (DUF932)
HPFPGLDM_00033	5.15e-13	-	-	-	-	-	-	-	-
HPFPGLDM_00034	5.91e-25	-	-	-	K	ko:K06919	-	ko00000	Psort location Cytoplasmic, score
HPFPGLDM_00036	5.7e-105	-	-	-	S	-	-	-	Meiotically up-regulated gene 113
HPFPGLDM_00037	0.0	-	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	Restriction endonuclease, type I, EcoRI, R subunit Type III
HPFPGLDM_00038	2.4e-95	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
HPFPGLDM_00039	0.0	-	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	DNA methylase
HPFPGLDM_00040	5.89e-98	-	-	-	L	-	-	-	PD-(D/E)XK nuclease superfamily
HPFPGLDM_00041	1.42e-37	-	-	-	-	-	-	-	-
HPFPGLDM_00046	9.42e-07	-	-	-	S	-	-	-	TM2 domain
HPFPGLDM_00050	6.79e-60	-	-	-	S	ko:K07126	-	ko00000	beta-lactamase activity
HPFPGLDM_00051	7.44e-125	-	-	-	S	-	-	-	Virulence protein RhuM family
HPFPGLDM_00052	1.55e-160	-	-	-	K	-	-	-	filamentation induced by cAMP protein Fic
HPFPGLDM_00053	3.44e-28	-	-	-	V	-	-	-	Restriction endonuclease
HPFPGLDM_00054	5.65e-42	-	-	-	S	-	-	-	von Willebrand factor type A domain
HPFPGLDM_00055	1.36e-05	-	-	-	KLT	-	-	-	Lanthionine synthetase C-like protein
HPFPGLDM_00058	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HPFPGLDM_00059	2.91e-38	-	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L35
HPFPGLDM_00060	5.25e-79	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HPFPGLDM_00061	0.0	-	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	Peptidase family M50
HPFPGLDM_00064	0.0	-	-	-	L	-	-	-	UvrD/REP helicase N-terminal domain
HPFPGLDM_00065	0.0	-	-	-	L	-	-	-	PD-(D/E)XK nuclease superfamily
HPFPGLDM_00066	1.59e-213	MA20_36650	-	-	EG	-	-	-	spore germination
HPFPGLDM_00067	0.0	-	-	-	S	-	-	-	Alpha-2-macroglobulin family
HPFPGLDM_00068	5.33e-287	-	-	-	C	-	-	-	Iron-containing alcohol dehydrogenase
HPFPGLDM_00070	2.89e-123	-	2.1.1.63	-	L	ko:K00567	-	ko00000,ko01000,ko03400	6-O-methylguanine DNA methyltransferase, DNA binding domain
HPFPGLDM_00073	1.79e-213	-	-	-	-	-	-	-	-
HPFPGLDM_00074	3.97e-152	-	-	-	O	-	-	-	Glycoprotease family
HPFPGLDM_00075	4.28e-274	-	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Citrate synthase, C-terminal domain
HPFPGLDM_00077	3.86e-112	-	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HPFPGLDM_00078	4.12e-139	-	-	-	L	-	-	-	RNase_H superfamily
HPFPGLDM_00079	6.68e-103	smpB	-	-	O	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HPFPGLDM_00080	4.3e-44	-	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	RNA polymerase activity
HPFPGLDM_00081	1.43e-135	-	5.4.99.20	-	J	ko:K06181	-	ko00000,ko01000,ko03009	RNA pseudouridylate synthase
HPFPGLDM_00082	1.26e-214	-	-	-	-	-	-	-	-
HPFPGLDM_00083	1.3e-104	-	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	NDK
HPFPGLDM_00084	1.36e-207	-	-	-	S	-	-	-	Glycosyltransferase like family 2
HPFPGLDM_00085	4.12e-225	-	-	-	M	-	-	-	Glycosyl transferase family 2
HPFPGLDM_00086	1.34e-07	-	-	-	NU	-	-	-	Prokaryotic N-terminal methylation motif
HPFPGLDM_00087	7.26e-285	-	-	-	NU	ko:K02653	-	ko00000,ko02035,ko02044	Type II secretion system (T2SS), protein F
HPFPGLDM_00088	0.0	-	-	-	NU	ko:K02652	-	ko00000,ko02035,ko02044	Type II secretion system (T2SS), protein E, N-terminal domain
HPFPGLDM_00089	0.0	-	-	-	NU	ko:K02652	-	ko00000,ko02035,ko02044	Type II/IV secretion system protein
HPFPGLDM_00090	5.14e-245	-	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HPFPGLDM_00091	2.83e-110	-	-	-	S	-	-	-	Control of competence regulator ComK, YlbF/YmcA
HPFPGLDM_00092	1.1e-280	-	2.6.1.1	-	E	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	DegT/DnrJ/EryC1/StrS aminotransferase family
HPFPGLDM_00093	0.0	murJ	-	-	S	ko:K03980	-	ko00000,ko01011,ko02000	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
HPFPGLDM_00094	1.26e-271	-	-	-	IM	-	-	-	Cytidylyltransferase-like
HPFPGLDM_00095	1.74e-157	-	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	Iron/manganese superoxide dismutases, alpha-hairpin domain
HPFPGLDM_00096	0.0	-	-	-	S	-	-	-	Glycosyl hydrolase-like 10
HPFPGLDM_00097	1.32e-169	-	-	-	S	ko:K06898	-	ko00000	AIR carboxylase
HPFPGLDM_00098	3.41e-191	-	-	-	L	ko:K06864	-	ko00000	tRNA processing
HPFPGLDM_00099	1.01e-292	larC	4.99.1.12	-	S	ko:K09121	-	ko00000,ko01000	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
HPFPGLDM_00100	1.07e-238	-	2.5.1.90	-	H	ko:K02523	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Polyprenyl synthetase
HPFPGLDM_00101	0.0	-	-	-	E	ko:K03305	-	ko00000	POT family
HPFPGLDM_00102	0.0	-	5.2.1.8	-	O	ko:K03770	-	ko00000,ko01000,ko03110	PPIC-type PPIASE domain
HPFPGLDM_00103	2.39e-126	-	-	-	S	-	-	-	Pfam:DUF59
HPFPGLDM_00104	2.59e-107	-	-	-	-	-	-	-	-
HPFPGLDM_00106	3.12e-219	-	-	-	E	-	-	-	Domain of unknown function (DUF3472)
HPFPGLDM_00107	0.0	nuoN	1.6.5.3	-	C	ko:K00343	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HPFPGLDM_00108	0.0	-	1.6.5.3	-	C	ko:K00342	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Proton-conducting membrane transporter
HPFPGLDM_00109	0.0	-	1.6.5.3	-	CP	ko:K00341	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus
HPFPGLDM_00110	6.01e-61	nuoK	1.6.5.3	-	C	ko:K00340	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HPFPGLDM_00111	7.62e-157	-	1.6.5.3	-	C	ko:K00339	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NADH-ubiquinone/plastoquinone oxidoreductase chain 6
HPFPGLDM_00112	1.8e-124	nuoI	1.6.5.3	-	C	ko:K00338	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HPFPGLDM_00113	1.22e-308	nuoH	1.6.5.3	-	C	ko:K00337	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
HPFPGLDM_00114	0.0	-	1.6.5.3	-	C	ko:K00336	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region
HPFPGLDM_00115	0.0	-	1.6.5.3	-	C	ko:K00335	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region
HPFPGLDM_00116	2.88e-142	-	1.6.5.3	-	C	ko:K00334	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Thioredoxin-like [2Fe-2S] ferredoxin
HPFPGLDM_00117	4.39e-307	nuoD	1.6.5.3	-	C	ko:K00333	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HPFPGLDM_00119	0.0	-	-	-	G	-	-	-	Polysaccharide deacetylase
HPFPGLDM_00120	0.0	-	-	-	P	-	-	-	Putative Na+/H+ antiporter
HPFPGLDM_00121	1.07e-141	-	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Lumazine binding domain
HPFPGLDM_00122	8.45e-204	-	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase (PrmA)
HPFPGLDM_00123	0.0	pmp21	-	-	T	-	-	-	pathogenesis
HPFPGLDM_00124	0.0	-	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	4-alpha-glucanotransferase
HPFPGLDM_00126	0.0	-	2.8.4.4	-	J	ko:K14441	-	ko00000,ko01000,ko03009	Uncharacterized protein family UPF0004
HPFPGLDM_00127	0.0	-	-	-	-	ko:K07403	-	ko00000	-
HPFPGLDM_00128	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HPFPGLDM_00129	0.0	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HPFPGLDM_00130	1.52e-186	-	3.4.13.22	-	M	ko:K08641	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-ala-D-ala dipeptidase
HPFPGLDM_00132	0.0	-	-	-	E	-	-	-	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HPFPGLDM_00133	0.0	-	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	tail specific protease
HPFPGLDM_00134	8.06e-216	-	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Cytidylyltransferase family
HPFPGLDM_00135	0.0	-	3.6.4.13	-	L	ko:K03579	-	ko00000,ko01000	ATP-dependent helicase C-terminal
HPFPGLDM_00136	0.0	-	-	-	P	ko:K03306	-	ko00000	phosphate transporter
HPFPGLDM_00137	4.61e-309	-	-	-	O	-	-	-	peroxiredoxin activity
HPFPGLDM_00138	0.0	-	2.7.7.19	-	J	ko:K00970	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Poly A polymerase head domain
HPFPGLDM_00139	0.0	-	-	-	G	-	-	-	Alpha amylase, catalytic domain
HPFPGLDM_00140	0.0	-	-	-	NU	ko:K02453	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02044	Bacterial type II and III secretion system protein
HPFPGLDM_00141	0.0	-	-	-	-	-	-	-	-
HPFPGLDM_00142	7.21e-183	-	-	-	S	ko:K09778	-	ko00000	Domain of unknown function (DUF374)
HPFPGLDM_00143	7.21e-203	folD	1.5.1.5, 3.5.4.9	-	H	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HPFPGLDM_00144	8.33e-182	-	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
HPFPGLDM_00145	2.62e-202	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HPFPGLDM_00146	1.7e-284	-	-	-	E	-	-	-	Transglutaminase-like superfamily
HPFPGLDM_00147	8.69e-261	-	-	-	J	ko:K05541	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HPFPGLDM_00148	1.31e-289	-	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	LytB protein
HPFPGLDM_00150	2.34e-43	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S20
HPFPGLDM_00151	5.74e-142	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HPFPGLDM_00152	0.0	-	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Thiamine pyrophosphate enzyme, central domain
HPFPGLDM_00155	3.25e-223	-	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Phosphatidylserine decarboxylase
HPFPGLDM_00156	2.22e-151	-	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribulose-phosphate 3 epimerase family
HPFPGLDM_00157	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Leucyl-tRNA synthetase, Domain 2
HPFPGLDM_00158	0.0	-	-	-	P	-	-	-	Sulfatase
HPFPGLDM_00160	1.75e-299	-	4.1.1.96	-	E	ko:K13747	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	Pyridoxal-dependent decarboxylase, C-terminal sheet domain
HPFPGLDM_00161	0.0	-	4.1.1.19	-	E	ko:K01585	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Pyridoxal-dependent decarboxylase, pyridoxal binding domain
HPFPGLDM_00162	7.52e-265	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HPFPGLDM_00163	1.61e-184	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
HPFPGLDM_00164	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Beta galactosidase small chain
HPFPGLDM_00165	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase activity
HPFPGLDM_00166	0.0	rarA	-	-	L	ko:K07478	-	ko00000	MgsA AAA+ ATPase C terminal
HPFPGLDM_00167	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	PFAM Glycoside hydrolase, family 20, catalytic core
HPFPGLDM_00169	3.87e-301	-	2.7.1.11, 2.7.1.90	-	H	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions
HPFPGLDM_00170	3.52e-214	-	-	-	M	-	-	-	Carbohydrate esterase, sialic acid-specific acetylesterase
HPFPGLDM_00171	2.18e-269	-	-	-	K	-	-	-	Periplasmic binding protein-like domain
HPFPGLDM_00175	4.36e-263	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HPFPGLDM_00176	5.85e-248	-	3.1.21.4	-	L	ko:K01155	-	ko00000,ko01000,ko02048	Type III restriction enzyme res subunit
HPFPGLDM_00177	0.0	-	-	-	L	-	-	-	Type III restriction enzyme res subunit
HPFPGLDM_00178	4.46e-127	cobU	2.7.1.156, 2.7.7.62, 6.3.5.10	-	H	ko:K02231,ko:K02232	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	cobinamide kinase activity
HPFPGLDM_00179	1.41e-207	-	-	-	G	-	-	-	myo-inosose-2 dehydratase activity
HPFPGLDM_00180	1.62e-172	cobS	2.7.8.26	-	H	ko:K02233	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
HPFPGLDM_00181	6.66e-238	cobT	2.4.2.21	-	H	ko:K00768	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
HPFPGLDM_00182	4.33e-235	cobD	6.3.1.10	-	H	ko:K02227	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
HPFPGLDM_00183	0.0	cobQ	-	-	H	-	-	-	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
HPFPGLDM_00184	0.0	-	-	-	H	ko:K02014	-	ko00000,ko02000	TonB dependent receptor
HPFPGLDM_00185	0.0	-	-	-	E	ko:K13893	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HPFPGLDM_00186	0.0	-	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Glycosyl hydrolases family 35
HPFPGLDM_00187	6.65e-160	-	-	-	M	ko:K16079	-	ko00000,ko02000	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HPFPGLDM_00188	4.66e-313	-	3.5.4.28, 3.5.4.31	-	F	ko:K12960	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Amidohydrolase family
HPFPGLDM_00189	0.0	-	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HPFPGLDM_00190	1.31e-94	-	-	-	S	-	-	-	Nucleotidyltransferase substrate binding protein like
HPFPGLDM_00191	8.04e-60	-	3.4.11.5	-	S	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	nucleotidyltransferase activity
HPFPGLDM_00192	2.81e-225	-	2.3.1.61	-	C	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	2-oxoacid dehydrogenases acyltransferase (catalytic domain)
HPFPGLDM_00193	0.0	-	1.2.4.2	-	C	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	2-oxoglutarate dehydrogenase C-terminal
HPFPGLDM_00194	1.48e-245	-	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome bd terminal oxidase subunit II
HPFPGLDM_00195	0.0	-	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome bd terminal oxidase subunit I
HPFPGLDM_00196	1.56e-112	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
HPFPGLDM_00197	1.35e-106	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Low molecular weight phosphatase family
HPFPGLDM_00198	0.0	-	-	-	T	-	-	-	Chase2 domain
HPFPGLDM_00199	1.02e-233	-	2.7.1.221	-	S	ko:K07102	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Phosphotransferase enzyme family
HPFPGLDM_00200	1.25e-307	-	4.2.1.20	-	E	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HPFPGLDM_00201	4.98e-92	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HPFPGLDM_00203	2.46e-113	-	1.16.3.2	-	P	ko:K02217	-	ko00000,ko01000	Ferritin-like domain
HPFPGLDM_00204	0.0	-	-	-	-	-	-	-	-
HPFPGLDM_00205	3.15e-103	-	-	-	J	-	-	-	YjgF/chorismate_mutase-like, putative endoribonuclease
HPFPGLDM_00207	7.16e-115	-	-	-	S	ko:K03748	-	ko00000	DUF218 domain
HPFPGLDM_00209	8.35e-232	-	-	-	S	-	-	-	mannose-ethanolamine phosphotransferase activity
HPFPGLDM_00215	0.0	-	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	RQC
HPFPGLDM_00217	2.23e-176	-	-	-	-	-	-	-	-
HPFPGLDM_00218	2.25e-208	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HPFPGLDM_00219	2.18e-269	sucC	6.2.1.5	-	C	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HPFPGLDM_00220	4.43e-291	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HPFPGLDM_00221	5.49e-206	-	-	-	S	ko:K03453	-	ko00000	Bile acid
HPFPGLDM_00224	6.39e-71	-	-	-	-	-	-	-	-
HPFPGLDM_00225	0.0	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HPFPGLDM_00226	0.0	-	2.3.1.40, 6.2.1.20	-	IQ	ko:K05939	ko00071,ko00564,map00071,map00564	ko00000,ko00001,ko01000	AMP-binding enzyme
HPFPGLDM_00227	2.45e-53	-	-	-	U	-	-	-	Passenger-associated-transport-repeat
HPFPGLDM_00229	1.07e-205	-	1.4.1.16	-	S	ko:K03340	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
HPFPGLDM_00231	0.000103	-	-	-	S	-	-	-	Entericidin EcnA/B family
HPFPGLDM_00232	3.46e-234	-	-	-	S	ko:K07192	ko04910,map04910	ko00000,ko00001,ko03036,ko04131,ko04147	prohibitin homologues
HPFPGLDM_00233	3.03e-118	-	-	-	-	-	-	-	-
HPFPGLDM_00234	0.0	-	-	-	S	ko:K07263	-	ko00000,ko01000,ko01002	Insulinase (Peptidase family M16)
HPFPGLDM_00235	2.22e-298	lpxK	2.7.1.130	-	M	ko:K00912	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)
HPFPGLDM_00236	6.47e-139	-	-	-	S	ko:K07164	-	ko00000	C4-type zinc ribbon domain
HPFPGLDM_00237	2.24e-264	-	3.1.13.5	-	J	ko:K03684	-	ko00000,ko01000,ko03016	3'-5' exonuclease
HPFPGLDM_00238	3.68e-75	-	-	-	-	-	-	-	-
HPFPGLDM_00239	1.69e-190	-	3.6.1.66	-	S	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	MazG nucleotide pyrophosphohydrolase domain
HPFPGLDM_00240	2.92e-70	-	-	-	-	-	-	-	-
HPFPGLDM_00241	6.15e-183	-	-	-	S	-	-	-	competence protein
HPFPGLDM_00242	2.03e-101	-	-	-	S	ko:K07107	-	ko00000,ko01000	Thioesterase-like superfamily
HPFPGLDM_00246	0.0	-	3.1.6.1	-	P	ko:K01130	ko00140,ko00600,map00140,map00600	ko00000,ko00001,ko01000	Sulfatase
HPFPGLDM_00247	1.3e-143	-	-	-	-	-	-	-	-
HPFPGLDM_00248	9.08e-165	-	-	-	NU	-	-	-	Prokaryotic N-terminal methylation motif
HPFPGLDM_00249	9.74e-178	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HPFPGLDM_00250	6.39e-299	-	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	16S rRNA methyltransferase RsmB/F
HPFPGLDM_00251	2.97e-115	-	3.1.6.8	-	P	ko:K01134	ko00600,ko04142,map00600,map04142	ko00000,ko00001,ko01000	COG3119 Arylsulfatase A
HPFPGLDM_00252	2.9e-316	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Arginosuccinate synthase
HPFPGLDM_00254	2.79e-54	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HPFPGLDM_00255	8.43e-59	-	-	-	S	-	-	-	Zinc ribbon domain
HPFPGLDM_00256	4.77e-310	-	-	-	S	-	-	-	PFAM CBS domain containing protein
HPFPGLDM_00257	2.51e-151	-	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HII
HPFPGLDM_00258	4.83e-82	-	-	-	L	ko:K07460	-	ko00000	Uncharacterised protein family UPF0102
HPFPGLDM_00260	1.37e-176	-	4.1.1.48	-	E	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Indole-3-glycerol phosphate synthase
HPFPGLDM_00261	3.4e-229	-	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil DNA glycosylase superfamily
HPFPGLDM_00262	1.39e-157	-	-	-	S	-	-	-	3D domain
HPFPGLDM_00263	2.07e-149	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HPFPGLDM_00264	9.91e-171	-	-	-	U	ko:K03561	-	ko00000,ko02000	MotA/TolQ/ExbB proton channel family
HPFPGLDM_00265	9.16e-111	aglS	-	-	U	ko:K03559	-	ko00000,ko02000	biopolymer transport protein
HPFPGLDM_00266	2.15e-99	exbD2	-	-	U	ko:K03559	-	ko00000,ko02000	biopolymer transport protein
HPFPGLDM_00267	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
HPFPGLDM_00268	6.08e-192	-	-	-	-	-	-	-	-
HPFPGLDM_00269	8.99e-277	-	-	-	K	-	-	-	sequence-specific DNA binding
HPFPGLDM_00270	0.0	-	-	-	J	ko:K08301	-	ko00000,ko01000,ko03009,ko03019	Ribonuclease E/G family
HPFPGLDM_00271	5.06e-236	-	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Actin
HPFPGLDM_00272	0.0	lacZ_17	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase activity
HPFPGLDM_00274	2.24e-263	-	-	-	G	-	-	-	M42 glutamyl aminopeptidase
HPFPGLDM_00276	3.71e-177	-	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	CobB/CobQ-like glutamine amidotransferase domain
HPFPGLDM_00277	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate
HPFPGLDM_00278	5.55e-116	-	-	-	-	-	-	-	-
HPFPGLDM_00279	1.89e-166	-	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	SAICAR synthetase
HPFPGLDM_00280	0.0	-	-	-	K	-	-	-	Transcription elongation factor, N-terminal
HPFPGLDM_00281	0.0	-	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HPFPGLDM_00282	1.71e-179	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HPFPGLDM_00283	1.17e-305	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HPFPGLDM_00284	6.67e-202	-	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Serine acetyltransferase, N-terminal
HPFPGLDM_00285	1.06e-109	-	-	-	S	ko:K15977	-	ko00000	DoxX
HPFPGLDM_00286	2.76e-292	-	4.2.1.129, 5.4.99.17	-	I	ko:K06045	ko00909,ko01110,map00909,map01110	ko00000,ko00001,ko01000	PFAM Prenyltransferase squalene oxidase
HPFPGLDM_00287	5.49e-192	-	-	-	-	-	-	-	-
HPFPGLDM_00288	1.18e-224	-	5.3.1.13	-	M	ko:K06041	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	SIS domain
HPFPGLDM_00289	9.39e-183	-	-	-	H	-	-	-	ThiF family
HPFPGLDM_00290	8.92e-111	-	-	-	U	-	-	-	response to pH
HPFPGLDM_00291	1.18e-222	-	-	-	-	-	-	-	-
HPFPGLDM_00292	4.09e-218	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HPFPGLDM_00294	0.0	-	-	-	G	-	-	-	Raffinose synthase or seed imbibition protein Sip1
HPFPGLDM_00295	3.11e-271	-	-	-	S	-	-	-	COGs COG4299 conserved
HPFPGLDM_00296	5.1e-153	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
HPFPGLDM_00297	0.0	-	3.4.16.4	-	M	ko:K05515	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein dimerisation domain
HPFPGLDM_00298	0.0	-	-	-	-	-	-	-	-
HPFPGLDM_00299	6.27e-219	-	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	ATP synthase A chain
HPFPGLDM_00300	5.65e-09	-	-	-	S	-	-	-	ATP synthase subunit C
HPFPGLDM_00301	4.38e-78	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	ATP synthase B/B' CF(0)
HPFPGLDM_00302	6.46e-86	-	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	ATP synthase delta (OSCP) subunit
HPFPGLDM_00303	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HPFPGLDM_00304	4.5e-201	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HPFPGLDM_00305	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HPFPGLDM_00306	5.04e-90	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HPFPGLDM_00307	3.95e-139	-	-	-	-	-	-	-	-
HPFPGLDM_00308	3.33e-123	sprT	-	-	K	-	-	-	SprT-like family
HPFPGLDM_00309	1.49e-275	-	-	-	S	-	-	-	COGs COG4299 conserved
HPFPGLDM_00310	4.88e-284	-	2.6.1.59	-	M	ko:K02805	-	ko00000,ko01000,ko01007	DegT/DnrJ/EryC1/StrS aminotransferase family
HPFPGLDM_00311	1.72e-114	flmH	2.3.1.57	-	J	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	ko00000,ko00001,ko00002,ko01000	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HPFPGLDM_00312	5.15e-218	-	-	-	M	-	-	-	Glycosyl transferase family 2
HPFPGLDM_00313	1.08e-73	-	-	-	P	ko:K03297,ko:K11741	-	ko00000,ko02000	Multidrug Resistance protein
HPFPGLDM_00314	1.93e-77	-	-	-	P	ko:K03297,ko:K11741	-	ko00000,ko02000	Multidrug Resistance protein
HPFPGLDM_00317	6.28e-136	-	-	-	F	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
HPFPGLDM_00318	0.0	-	2.6.1.62	-	H	ko:K00833	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
HPFPGLDM_00319	7.19e-234	-	2.8.1.6	-	H	ko:K01012	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Biotin and Thiamin Synthesis associated domain
HPFPGLDM_00320	0.0	-	-	-	P	-	-	-	Sulfatase
HPFPGLDM_00321	0.0	-	-	-	M	-	-	-	Bacterial membrane protein, YfhO
HPFPGLDM_00322	6.11e-295	-	-	-	O	ko:K09015	-	ko00000	Uncharacterized protein family (UPF0051)
HPFPGLDM_00323	0.0	-	-	-	O	ko:K09014	-	ko00000	Uncharacterized protein family (UPF0051)
HPFPGLDM_00324	1.24e-179	-	-	-	O	ko:K09013	-	ko00000,ko02000	ATPases associated with a variety of cellular activities
HPFPGLDM_00325	2.76e-99	-	-	-	P	ko:K09825	-	ko00000,ko03000	Ferric uptake regulator family
HPFPGLDM_00326	2.14e-57	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L27 protein
HPFPGLDM_00327	1.93e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal prokaryotic L21 protein
HPFPGLDM_00328	6.74e-106	-	-	-	S	ko:K06925	-	ko00000,ko03016	Threonylcarbamoyl adenosine biosynthesis protein TsaE
HPFPGLDM_00329	2.16e-199	-	-	-	S	ko:K06889	-	ko00000	alpha beta
HPFPGLDM_00331	0.0	-	-	-	M	-	-	-	Parallel beta-helix repeats
HPFPGLDM_00332	0.0	-	-	-	-	-	-	-	-
HPFPGLDM_00333	2.58e-225	-	-	-	S	-	-	-	Polyphosphate kinase 2 (PPK2)
HPFPGLDM_00335	1.36e-175	-	-	-	-	-	-	-	-
HPFPGLDM_00336	3.35e-131	-	-	-	L	-	-	-	Conserved hypothetical protein 95
HPFPGLDM_00337	1.67e-309	-	2.4.99.12, 2.4.99.13, 2.4.99.14, 2.4.99.15	GT30	M	ko:K02527	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase)
HPFPGLDM_00338	3.24e-224	-	-	-	S	-	-	-	Aspartyl protease
HPFPGLDM_00339	1.67e-272	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HPFPGLDM_00340	8.3e-158	-	6.3.2.5	-	H	ko:K21977	ko00770,map00770	ko00000,ko00001,ko00002,ko01000	DNA / pantothenate metabolism flavoprotein
HPFPGLDM_00341	1.38e-278	-	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class-V
HPFPGLDM_00342	1.94e-104	-	-	-	K	ko:K03826	-	ko00000,ko01000	acetyltransferase
HPFPGLDM_00343	2.48e-173	-	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
HPFPGLDM_00344	0.0	-	-	-	L	-	-	-	Polyphosphate kinase 2 (PPK2)
HPFPGLDM_00345	0.0	-	-	-	S	-	-	-	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
HPFPGLDM_00346	9.81e-261	-	-	-	M	-	-	-	Peptidase family M23
HPFPGLDM_00348	8.37e-126	-	4.1.1.36	-	H	ko:K01598	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Flavoprotein
HPFPGLDM_00349	1.31e-81	-	-	-	DJ	-	-	-	Addiction module toxin, RelE StbE family
HPFPGLDM_00350	1.35e-207	-	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
HPFPGLDM_00352	7.27e-139	-	-	-	K	ko:K03088	-	ko00000,ko03021	ECF sigma factor
HPFPGLDM_00353	0.0	-	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HPFPGLDM_00354	4.07e-246	-	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	AIR synthase related protein, N-terminal domain
HPFPGLDM_00355	1.84e-105	-	-	-	S	ko:K15977	-	ko00000	DoxX
HPFPGLDM_00356	1.72e-243	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
HPFPGLDM_00357	0.0	-	3.1.1.53	-	E	ko:K05970	-	ko00000,ko01000	Carbohydrate esterase, sialic acid-specific acetylesterase
HPFPGLDM_00358	1.84e-177	-	-	-	-	-	-	-	-
HPFPGLDM_00359	0.0	-	3.6.4.13	-	L	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DbpA RNA binding domain
HPFPGLDM_00360	0.0	-	-	-	P	ko:K01138	-	ko00000,ko01000	PA14 domain
HPFPGLDM_00361	2.42e-147	-	-	-	L	-	-	-	Membrane
HPFPGLDM_00363	0.0	gcvP	1.4.4.2	-	E	ko:K00281	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HPFPGLDM_00364	6.67e-86	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
HPFPGLDM_00365	3.47e-268	gcvT	2.1.2.10	-	E	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Aminomethyltransferase folate-binding domain
HPFPGLDM_00366	5.5e-262	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HPFPGLDM_00367	1.27e-220	-	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
HPFPGLDM_00368	2.77e-272	-	-	-	LU	ko:K04096	-	ko00000	DNA recombination-mediator protein A
HPFPGLDM_00369	8.91e-271	-	-	-	M	-	-	-	Glycosyl transferase 4-like
HPFPGLDM_00370	1.18e-224	-	-	-	M	ko:K07276	-	ko00000	Mitochondrial fission ELM1
HPFPGLDM_00371	6.74e-271	-	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Domain of unknown function (DUF1730)
HPFPGLDM_00372	1.11e-79	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HPFPGLDM_00373	2.11e-121	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HPFPGLDM_00374	4.36e-142	-	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S4/S9 N-terminal domain
HPFPGLDM_00375	1.71e-192	-	-	-	E	-	-	-	haloacid dehalogenase-like hydrolase
HPFPGLDM_00379	1.93e-127	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HPFPGLDM_00380	0.0	-	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Pyruvate kinase, barrel domain
HPFPGLDM_00381	2.63e-292	-	3.5.1.42	-	S	ko:K03742	ko00760,map00760	ko00000,ko00001,ko01000	Competence-damaged protein
HPFPGLDM_00382	7e-154	-	-	-	O	-	-	-	methyltransferase activity
HPFPGLDM_00383	4.46e-189	-	-	-	U	ko:K20276	ko02024,map02024	ko00000,ko00001	domain, Protein
HPFPGLDM_00384	0.0	-	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	DnaB-like helicase C terminal domain
HPFPGLDM_00385	2.62e-262	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Elongator protein 3, MiaB family, Radical SAM
HPFPGLDM_00386	1.1e-197	-	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	SRP54-type protein, GTPase domain
HPFPGLDM_00387	2.83e-206	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HPFPGLDM_00388	7.32e-105	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HPFPGLDM_00389	1.42e-289	-	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase II
HPFPGLDM_00390	0.0	glnS	6.1.1.18	-	J	ko:K01886	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class I (E and Q), anti-codon binding domain
HPFPGLDM_00391	0.0	-	-	-	-	-	-	-	-
HPFPGLDM_00392	0.0	-	-	-	EGP	-	-	-	Sugar (and other) transporter
HPFPGLDM_00393	6.9e-259	-	-	-	S	-	-	-	ankyrin repeats
HPFPGLDM_00394	1.55e-313	hemL	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
HPFPGLDM_00395	1.06e-44	-	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S21
HPFPGLDM_00396	0.0	-	2.7.1.167, 2.7.7.70	-	M	ko:K03272	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	pfkB family carbohydrate kinase
HPFPGLDM_00397	8.25e-131	-	5.3.1.28	-	G	ko:K03271	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	SIS domain
HPFPGLDM_00398	6.23e-118	-	3.1.3.82, 3.1.3.83	-	E	ko:K03273	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Polynucleotide kinase 3 phosphatase
HPFPGLDM_00399	1.26e-222	hyl	2.3.1.48, 3.2.1.169, 3.2.1.35	GH84	G	ko:K01197,ko:K15719	ko00531,ko01100,ko04931,map00531,map01100,map04931	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	beta-N-acetylhexosaminidase activity
HPFPGLDM_00401	2.76e-247	-	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	NMT1/THI5 like
HPFPGLDM_00402	1.63e-189	-	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HPFPGLDM_00403	8.12e-195	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HPFPGLDM_00404	5.68e-188	lpxD	2.3.1.191	-	M	ko:K02536	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HPFPGLDM_00405	1.48e-120	-	-	-	M	ko:K06142	-	ko00000	Outer membrane protein (OmpH-like)
HPFPGLDM_00406	8.39e-197	panC	6.3.2.1	-	H	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HPFPGLDM_00407	1.83e-150	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HPFPGLDM_00409	6.25e-144	-	-	-	-	-	-	-	-
HPFPGLDM_00410	8.41e-202	-	-	-	S	-	-	-	DisA bacterial checkpoint controller nucleotide-binding
HPFPGLDM_00412	1.7e-153	-	6.3.3.3	-	H	ko:K01935	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	AAA domain
HPFPGLDM_00413	0.0	-	-	-	G	-	-	-	beta-N-acetylhexosaminidase activity
HPFPGLDM_00414	0.0	-	-	-	S	-	-	-	Type I phosphodiesterase / nucleotide pyrophosphatase
HPFPGLDM_00415	1.8e-181	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HPFPGLDM_00417	1.33e-174	-	-	-	NU	-	-	-	Prepilin-type N-terminal cleavage methylation domain
HPFPGLDM_00419	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	PFAM coagulation factor 5 8 type domain protein
HPFPGLDM_00420	9.86e-168	-	-	-	M	-	-	-	Peptidase family M23
HPFPGLDM_00421	1.04e-144	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HPFPGLDM_00422	2.16e-200	-	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HPFPGLDM_00425	0.0	-	-	-	S	-	-	-	Terminase
HPFPGLDM_00426	1.66e-213	-	-	-	D	ko:K19234,ko:K19236	ko01503,map01503	ko00000,ko00001,ko01002,ko01011	ErfK ybiS ycfS ynhG family protein
HPFPGLDM_00427	3.3e-151	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HPFPGLDM_00428	3.01e-49	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal_S15
HPFPGLDM_00429	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HPFPGLDM_00430	2.59e-312	tlyC	-	-	S	ko:K03699	-	ko00000,ko02042	PFAM CBS domain containing protein
HPFPGLDM_00431	2.67e-308	-	-	-	S	-	-	-	PFAM CBS domain containing protein
HPFPGLDM_00432	0.0	-	-	-	C	-	-	-	Cytochrome c554 and c-prime
HPFPGLDM_00433	1.39e-165	-	-	-	CO	-	-	-	Thioredoxin-like
HPFPGLDM_00434	1.1e-159	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HPFPGLDM_00435	4.7e-156	-	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Thiamine monophosphate synthase
HPFPGLDM_00436	4.25e-238	pyrD	1.3.5.2	-	F	ko:K00254	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Dihydroorotate dehydrogenase
HPFPGLDM_00437	0.0	-	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase alpha chain like domain
HPFPGLDM_00438	5.21e-142	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HPFPGLDM_00439	0.0	-	4.1.1.15	-	E	ko:K01580	ko00250,ko00410,ko00430,ko00650,ko01100,ko01110,ko01120,ko02024,ko04727,ko04940,map00250,map00410,map00430,map00650,map01100,map01110,map01120,map02024,map04727,map04940	ko00000,ko00001,ko00002,ko01000	Pyridoxal-dependent decarboxylase conserved domain
HPFPGLDM_00440	0.0	-	-	-	-	-	-	-	-
HPFPGLDM_00442	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	PFAM Glycoside hydrolase, family 20, catalytic core
HPFPGLDM_00444	0.0	-	-	-	P	ko:K03281	-	ko00000	Voltage gated chloride channel
HPFPGLDM_00445	0.0	-	-	-	KT	ko:K02584	ko02020,map02020	ko00000,ko00001,ko03000	Bacterial regulatory protein, Fis family
HPFPGLDM_00446	9.68e-221	-	2.5.1.21	-	I	ko:K00801	ko00100,ko00909,ko01100,ko01110,ko01130,map00100,map00909,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko01006	Squalene/phytoene synthase
HPFPGLDM_00447	0.0	-	-	-	S	-	-	-	Fungal chitosanase of glycosyl hydrolase group 75
HPFPGLDM_00448	2.58e-191	-	-	-	S	ko:K07124	-	ko00000	Enoyl-(Acyl carrier protein) reductase
HPFPGLDM_00449	8.38e-98	-	-	-	-	-	-	-	-
HPFPGLDM_00450	0.0	-	-	-	V	-	-	-	ABC-2 type transporter
HPFPGLDM_00453	9.85e-147	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
HPFPGLDM_00457	1.85e-302	-	-	-	MU	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	efflux transmembrane transporter activity
HPFPGLDM_00460	4.36e-200	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Enoyl-CoA hydratase/isomerase
HPFPGLDM_00461	1.29e-257	-	-	-	S	-	-	-	AAA domain, putative AbiEii toxin, Type IV TA system
HPFPGLDM_00463	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HPFPGLDM_00464	4.69e-79	rsfS	-	-	S	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HPFPGLDM_00465	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HPFPGLDM_00466	9.22e-141	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Exonuclease
HPFPGLDM_00467	3.99e-176	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HPFPGLDM_00468	0.0	-	-	-	CO	-	-	-	Disulphide bond corrector protein DsbC
HPFPGLDM_00469	3.08e-93	-	-	-	O	-	-	-	OsmC-like protein
HPFPGLDM_00471	3.42e-111	-	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	Cytidine and deoxycytidylate deaminase zinc-binding region
HPFPGLDM_00472	0.0	-	-	-	EGIP	-	-	-	Phosphate acyltransferases
HPFPGLDM_00474	3.06e-206	-	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydrogenase
HPFPGLDM_00475	0.0	-	-	-	P	ko:K02014	-	ko00000,ko02000	TonB dependent receptor
HPFPGLDM_00476	1.22e-168	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HPFPGLDM_00477	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HPFPGLDM_00480	6.2e-155	cat	2.3.1.28	-	V	ko:K19271	-	br01600,ko00000,ko01000,ko01504	Chloramphenicol acetyltransferase
HPFPGLDM_00481	5.03e-230	-	-	-	EP	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
HPFPGLDM_00482	0.0	der	-	-	S	ko:K03977	-	ko00000,ko03009	KH-domain-like of EngA bacterial GTPase enzymes, C-terminal
HPFPGLDM_00483	9.67e-251	-	-	-	S	ko:K07091	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Predicted permease YjgP/YjgQ family
HPFPGLDM_00484	4.49e-125	-	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Recombination protein O N terminal
HPFPGLDM_00485	1.14e-182	-	-	-	S	-	-	-	Tetratricopeptide repeat
HPFPGLDM_00486	0.0	dxs	2.2.1.7	-	HI	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HPFPGLDM_00487	3.08e-52	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease VII activity
HPFPGLDM_00488	0.0	-	-	-	O	-	-	-	C-terminal four TMM region of protein-O-mannosyltransferase
HPFPGLDM_00489	0.0	-	-	-	T	-	-	-	Bacterial regulatory protein, Fis family
HPFPGLDM_00490	1.82e-274	-	-	-	T	-	-	-	PAS domain
HPFPGLDM_00491	3.37e-97	-	-	-	S	ko:K07107	-	ko00000,ko01000	Thioesterase superfamily
HPFPGLDM_00492	0.0	gpmI	5.4.2.12	-	G	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	BPG-independent PGAM N-terminus (iPGM_N)
HPFPGLDM_00493	4.16e-85	-	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S12/S23
HPFPGLDM_00494	2.91e-104	-	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S7p/S5e
HPFPGLDM_00495	0.0	-	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HPFPGLDM_00496	3.67e-65	-	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S10p/S20e
HPFPGLDM_00497	3.86e-149	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HPFPGLDM_00498	9.43e-132	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L4/L1 family
HPFPGLDM_00499	8.72e-58	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HPFPGLDM_00500	1.85e-203	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HPFPGLDM_00501	1.05e-58	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HPFPGLDM_00502	4.05e-152	-	-	-	-	-	-	-	-
HPFPGLDM_00503	4.97e-70	-	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome
HPFPGLDM_00504	4.27e-155	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HPFPGLDM_00505	3.42e-97	-	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HPFPGLDM_00506	5.78e-35	-	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L29 protein
HPFPGLDM_00507	2.19e-56	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HPFPGLDM_00508	6.79e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HPFPGLDM_00509	6.2e-203	-	-	-	-	-	-	-	-
HPFPGLDM_00510	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HPFPGLDM_00511	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Domain of unknown function (DUF4982)
HPFPGLDM_00512	2.73e-263	-	5.2.1.8	-	O	ko:K03771	-	ko00000,ko01000,ko03110	SurA N-terminal domain
HPFPGLDM_00513	3.02e-170	-	2.5.1.39	-	H	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
HPFPGLDM_00514	1.43e-142	-	-	-	U	ko:K03561	-	ko00000,ko02000	MotA/TolQ/ExbB proton channel family
HPFPGLDM_00520	1.9e-62	-	-	-	L	-	-	-	bacterial (prokaryotic) histone like domain
HPFPGLDM_00521	9.89e-207	-	3.1.26.4	-	L	ko:K03471	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HII
HPFPGLDM_00522	2.43e-126	-	-	-	M	ko:K03642	-	ko00000	Lytic transglycolase
HPFPGLDM_00523	4.32e-174	-	-	-	F	-	-	-	NUDIX domain
HPFPGLDM_00524	4.08e-149	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Putative methyltransferase
HPFPGLDM_00525	1.39e-282	tgt	2.4.2.29	-	J	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HPFPGLDM_00526	1.62e-65	-	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit
HPFPGLDM_00527	1.53e-184	-	-	-	DTZ	-	-	-	EF-hand, calcium binding motif
HPFPGLDM_00528	6.5e-215	-	-	-	L	ko:K03733	-	ko00000,ko03036	Phage integrase, N-terminal SAM-like domain
HPFPGLDM_00531	9.56e-51	-	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Ribosomal protein S16
HPFPGLDM_00532	1.09e-128	aroK	2.7.1.71	-	E	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HPFPGLDM_00533	2.96e-242	-	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HPFPGLDM_00534	1.71e-80	-	-	-	FG	ko:K02503	-	ko00000,ko04147	HIT domain
HPFPGLDM_00535	4.98e-117	-	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
HPFPGLDM_00536	2.73e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
HPFPGLDM_00537	1.22e-246	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HPFPGLDM_00538	0.0	-	-	-	S	ko:K07037	-	ko00000	7TM receptor with intracellular HD hydrolase
HPFPGLDM_00539	4.77e-116	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HPFPGLDM_00544	0.0	-	-	-	CO	-	-	-	Thioredoxin-like
HPFPGLDM_00551	7.45e-231	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	maintenance of DNA repeat elements
HPFPGLDM_00552	1.51e-73	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HPFPGLDM_00553	1.47e-232	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HPFPGLDM_00555	2.43e-174	-	-	-	P	ko:K10716	-	ko00000,ko02000	domain protein
HPFPGLDM_00556	0.0	htpG	-	-	O	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	Hsp90 protein
HPFPGLDM_00557	0.0	-	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	transmembrane transport
HPFPGLDM_00558	4.93e-287	-	-	-	P	ko:K03449	-	ko00000,ko02000	Major Facilitator Superfamily
HPFPGLDM_00559	2.34e-240	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Aminoacyl tRNA synthetase class II, N-terminal domain
HPFPGLDM_00560	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	B3/4 domain
HPFPGLDM_00561	5.85e-254	-	-	-	S	-	-	-	Domain of unknown function (DUF4105)
HPFPGLDM_00562	6.76e-143	-	-	-	M	-	-	-	Peptidoglycan-binding domain 1 protein
HPFPGLDM_00563	0.0	-	4.1.99.1	-	E	ko:K01667	ko00380,map00380	ko00000,ko00001,ko01000	Beta-eliminating lyase
HPFPGLDM_00564	2.01e-34	-	-	-	KLT	-	-	-	Tyrosine-protein kinase, subgroup, catalytic domain
HPFPGLDM_00565	1.33e-226	-	-	-	S	-	-	-	Protein conserved in bacteria
HPFPGLDM_00566	5.51e-211	-	-	-	S	-	-	-	ABC-type transport system involved in multi-copper enzyme maturation permease component
HPFPGLDM_00567	4.69e-159	-	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Methyladenine glycosylase
HPFPGLDM_00568	8.93e-181	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Pyrroline-5-carboxylate reductase dimerisation
HPFPGLDM_00571	1.59e-243	-	-	-	I	-	-	-	PFAM Prenyltransferase squalene oxidase
HPFPGLDM_00572	8.43e-131	-	-	-	-	-	-	-	-
HPFPGLDM_00573	0.0	-	-	-	D	-	-	-	nuclear chromosome segregation
HPFPGLDM_00574	0.0	-	5.4.99.2	-	I	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Methylmalonyl-CoA mutase
HPFPGLDM_00575	0.0	-	5.4.99.2	-	I	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Methylmalonyl-CoA mutase
HPFPGLDM_00577	3.13e-225	-	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	S-adenosylmethionine-dependent methyltransferase
HPFPGLDM_00578	2.72e-261	-	-	-	S	-	-	-	COG0790 FOG TPR repeat, SEL1 subfamily
HPFPGLDM_00579	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Phosphoglucose isomerase
HPFPGLDM_00580	0.0	-	2.7.9.1	-	G	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Pyruvate phosphate dikinase, PEP/pyruvate binding domain
HPFPGLDM_00581	1.22e-143	aat	2.3.2.6	-	O	ko:K00684	-	ko00000,ko01000	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
HPFPGLDM_00582	3.4e-258	-	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	endonuclease III
HPFPGLDM_00583	1.87e-219	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HPFPGLDM_00584	0.0	-	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen
HPFPGLDM_00586	1.11e-180	-	-	-	S	-	-	-	Integral membrane protein (intg_mem_TP0381)
HPFPGLDM_00587	1.12e-116	agmK	1.8.1.8	-	O	ko:K03671,ko:K03672	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko01000,ko03110	belongs to the thioredoxin family
HPFPGLDM_00588	2.52e-281	-	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
HPFPGLDM_00589	0.0	-	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
HPFPGLDM_00591	2.34e-108	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HPFPGLDM_00592	4.75e-171	-	-	-	S	-	-	-	Putative threonine/serine exporter
HPFPGLDM_00593	0.0	-	2.1.1.13	-	E	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	B12 binding domain
HPFPGLDM_00595	2.53e-146	-	-	-	Q	-	-	-	PA14
HPFPGLDM_00598	3.21e-104	-	-	-	-	-	-	-	-
HPFPGLDM_00599	0.0	mmyX	5.3.1.12	-	F	ko:K01812,ko:K07149,ko:K16139	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000,ko02000	Psort location Cytoplasmic, score
HPFPGLDM_00600	4.96e-113	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Cys-tRNA(Pro) hydrolase activity
HPFPGLDM_00602	3.55e-172	-	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Glutamine amidotransferase class-I
HPFPGLDM_00603	7.35e-119	-	-	-	T	ko:K07005	-	ko00000	pyridoxamine 5'-phosphate
HPFPGLDM_00604	4.33e-171	-	-	-	S	-	-	-	Integral membrane protein (intg_mem_TP0381)
HPFPGLDM_00606	1.1e-269	-	-	-	C	-	-	-	NADH:flavin oxidoreductase / NADH oxidase family
HPFPGLDM_00607	2.09e-150	-	4.1.3.27	-	EH	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Peptidase C26
HPFPGLDM_00608	3.63e-247	pabB	2.6.1.85, 4.1.3.27, 4.1.3.38	-	EH	ko:K01665,ko:K03342,ko:K13503,ko:K13950	ko00400,ko00790,ko01100,ko01110,ko01130,ko01230,map00400,map00790,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HPFPGLDM_00609	3.47e-153	-	4.1.3.38	-	E	ko:K02619	ko00790,map00790	ko00000,ko00001,ko01000	branched-chain-amino-acid transaminase activity
HPFPGLDM_00610	6.68e-314	-	5.1.3.8	-	G	ko:K01787	ko00520,map00520	ko00000,ko00001,ko01000	N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
HPFPGLDM_00611	1.38e-223	-	4.1.3.3	-	EM	ko:K01639	ko00520,map00520	ko00000,ko00001,ko01000	Dihydrodipicolinate synthetase family
HPFPGLDM_00612	0.0	-	-	-	-	-	-	-	-
HPFPGLDM_00613	9.24e-197	-	-	-	I	-	-	-	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
HPFPGLDM_00614	0.0	-	-	-	D	-	-	-	Tetratricopeptide repeat
HPFPGLDM_00615	4.37e-304	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HPFPGLDM_00616	0.0	-	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Adenylosuccinate lyase C-terminus
HPFPGLDM_00617	2.52e-102	MA20_05485	-	-	S	-	-	-	Putative bacterial sensory transduction regulator
HPFPGLDM_00618	9.22e-248	-	-	-	M	-	-	-	HlyD family secretion protein
HPFPGLDM_00619	0.0	-	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	Helix-hairpin-helix class 2 (Pol1 family) motifs
HPFPGLDM_00620	1.23e-123	-	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Phosphoribosyl transferase domain
HPFPGLDM_00622	1.93e-143	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
HPFPGLDM_00623	1.52e-245	-	-	-	S	-	-	-	Imelysin
HPFPGLDM_00624	0.0	-	-	-	C	-	-	-	Di-haem oxidoreductase, putative peroxidase
HPFPGLDM_00625	1.2e-264	-	-	-	J	-	-	-	Endoribonuclease L-PSP
HPFPGLDM_00626	1.79e-218	yclN	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	iron ion homeostasis
HPFPGLDM_00627	1.23e-228	fatC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	iron ion homeostasis
HPFPGLDM_00628	1.06e-180	yclP	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HPFPGLDM_00629	3.59e-211	fatB	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	iron ion transport
HPFPGLDM_00630	2.69e-185	ccs1	-	-	O	ko:K07399	-	ko00000	cytochrome c biogenesis protein
HPFPGLDM_00631	0.0	-	-	-	O	-	-	-	Cytochrome C assembly protein
HPFPGLDM_00632	1.52e-238	-	-	-	S	-	-	-	Acyltransferase family
HPFPGLDM_00633	0.0	-	-	-	G	-	-	-	beta-N-acetylhexosaminidase activity
HPFPGLDM_00634	4.58e-103	-	-	-	S	-	-	-	Protein of unknown function (DUF721)
HPFPGLDM_00635	1.33e-51	-	-	-	C	-	-	-	4Fe-4S single cluster domain of Ferredoxin I
HPFPGLDM_00636	0.0	-	-	GT2	M	ko:K03820	-	ko00000,ko01000	Carbon-nitrogen hydrolase
HPFPGLDM_00637	4.47e-176	-	-	-	S	-	-	-	Phosphodiester glycosidase
HPFPGLDM_00638	3.15e-228	-	2.7.7.13	-	JM	ko:K00966	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
HPFPGLDM_00639	0.0	fabZ	3.5.1.108, 4.2.1.59	-	IM	ko:K16363	ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis
HPFPGLDM_00640	2.13e-230	-	-	-	G	-	-	-	pfkB family carbohydrate kinase
HPFPGLDM_00641	2.98e-78	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HPFPGLDM_00643	2.98e-275	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Iron-containing alcohol dehydrogenase
HPFPGLDM_00646	1.11e-113	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
HPFPGLDM_00648	2.89e-14	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
HPFPGLDM_00650	1.3e-269	-	-	GT4	M	ko:K16703	-	ko00000,ko01000,ko01003	transferase activity, transferring glycosyl groups
HPFPGLDM_00651	3.81e-255	-	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HPFPGLDM_00652	3.32e-285	-	-	-	S	-	-	-	Phosphotransferase enzyme family
HPFPGLDM_00653	3.23e-253	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HPFPGLDM_00655	3.34e-139	-	-	-	T	-	-	-	histone H2A K63-linked ubiquitination
HPFPGLDM_00656	1.39e-130	-	2.1.1.63	-	L	ko:K00567	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HPFPGLDM_00657	5.11e-222	-	-	-	G	-	-	-	Glycosyl hydrolases family 16
HPFPGLDM_00658	8.55e-214	-	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HPFPGLDM_00659	0.0	-	-	-	T	ko:K06207	-	ko00000	Elongation factor G C-terminus
HPFPGLDM_00660	1.32e-235	-	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
HPFPGLDM_00661	1.38e-313	-	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-dependent decarboxylase, pyridoxal binding domain
HPFPGLDM_00662	6.62e-257	-	-	-	S	ko:K11744	-	ko00000	AI-2E family transporter
HPFPGLDM_00663	1.15e-155	gph	3.1.3.18, 3.6.1.1	-	S	ko:K01091,ko:K06019	ko00190,ko00630,ko01100,ko01110,ko01130,map00190,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	glycolate biosynthetic process
HPFPGLDM_00664	1.14e-294	-	-	-	E	-	-	-	Amino acid permease
HPFPGLDM_00665	2.02e-173	-	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Thiazole biosynthesis protein ThiG
HPFPGLDM_00667	1.79e-201	-	-	-	S	-	-	-	SigmaW regulon antibacterial
HPFPGLDM_00668	1.36e-242	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HPFPGLDM_00670	0.0	-	-	-	P	ko:K03455	-	ko00000	TrkA-N domain
HPFPGLDM_00671	0.0	-	-	-	P	-	-	-	Dimerisation domain of Zinc Transporter
HPFPGLDM_00672	1.67e-172	-	-	-	K	-	-	-	Transcriptional regulator
HPFPGLDM_00673	0.0	-	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HPFPGLDM_00674	6.66e-167	-	4.3.99.3	-	O	ko:K10026	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HPFPGLDM_00675	1.07e-201	-	2.7.13.3	-	Q	ko:K07777	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Transposase
HPFPGLDM_00676	0.0	-	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
HPFPGLDM_00677	2.56e-312	-	-	-	S	-	-	-	Protein of unknown function (DUF1015)
HPFPGLDM_00678	5.46e-234	-	-	-	E	-	-	-	Aminotransferase class-V
HPFPGLDM_00679	5.45e-234	-	-	-	S	-	-	-	Conserved hypothetical protein 698
HPFPGLDM_00680	1.12e-214	-	-	-	K	-	-	-	LysR substrate binding domain
HPFPGLDM_00683	2.82e-287	-	3.2.1.23	-	M	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
HPFPGLDM_00684	2.01e-293	-	3.2.1.23	-	M	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
HPFPGLDM_00685	2.29e-315	-	-	-	I	-	-	-	PFAM Prenyltransferase squalene oxidase
HPFPGLDM_00686	9.74e-298	-	4.2.1.129, 5.4.99.17, 5.5.1.16	-	I	ko:K06045,ko:K17811	ko00909,ko01110,map00909,map01110	ko00000,ko00001,ko01000	PFAM Prenyltransferase squalene oxidase
HPFPGLDM_00687	4e-261	-	-	-	M	ko:K02022	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HPFPGLDM_00688	2.13e-158	-	-	-	S	-	-	-	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HPFPGLDM_00690	5.12e-71	-	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Thioredoxin-like domain
HPFPGLDM_00691	7.81e-316	-	-	-	-	-	-	-	-
HPFPGLDM_00692	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class II (D, K and N)
HPFPGLDM_00694	0.0	-	-	-	T	-	-	-	pathogenesis
HPFPGLDM_00695	0.0	-	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HPFPGLDM_00696	2.17e-113	ywrF	-	-	S	-	-	-	FMN binding
HPFPGLDM_00697	9.27e-86	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HPFPGLDM_00698	0.0	-	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	UvrD-like helicase C-terminal domain
HPFPGLDM_00699	7.64e-307	-	-	-	M	-	-	-	OmpA family
HPFPGLDM_00700	0.0	-	6.3.2.45	-	M	ko:K02558	-	ko00000,ko01000	Mur ligase family, catalytic domain
HPFPGLDM_00701	5.39e-220	-	-	-	E	-	-	-	Phosphoserine phosphatase
HPFPGLDM_00702	6.31e-171	-	-	-	S	ko:K06861	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HPFPGLDM_00705	2.72e-197	-	2.5.1.55	-	M	ko:K01627	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	DAHP synthetase I family
HPFPGLDM_00706	1.1e-171	cbiX	4.99.1.3	-	S	ko:K03795	ko00860,ko01100,ko01120,map00860,map01100,map01120	ko00000,ko00001,ko01000	sirohydrochlorin cobaltochelatase activity
HPFPGLDM_00707	5.88e-163	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S2
HPFPGLDM_00708	2.05e-198	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HPFPGLDM_00709	7.6e-174	-	-	-	E	-	-	-	ATPases associated with a variety of cellular activities
HPFPGLDM_00711	5.91e-280	-	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	3-dehydroquinate synthase
HPFPGLDM_00712	0.0	-	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
HPFPGLDM_00713	0.0	-	-	-	O	-	-	-	Trypsin
HPFPGLDM_00714	4.99e-274	-	-	-	-	-	-	-	-
HPFPGLDM_00715	6.22e-146	-	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Aconitase C-terminal domain
HPFPGLDM_00716	0.0	-	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Aconitase family (aconitate hydratase)
HPFPGLDM_00717	2.05e-140	-	2.3.1.181	-	H	ko:K03801	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Biotin/lipoate A/B protein ligase family
HPFPGLDM_00718	6.69e-239	-	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Ami_3
HPFPGLDM_00719	1.15e-238	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HPFPGLDM_00720	1.8e-216	-	-	-	M	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	POTRA domain, FtsQ-type
HPFPGLDM_00721	1.44e-228	ddl	6.3.2.4	-	M	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	D-ala D-ala ligase N-terminus
HPFPGLDM_00722	0.0	murB	-	-	M	-	-	-	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain
HPFPGLDM_00723	1.31e-265	-	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HPFPGLDM_00724	1.33e-277	-	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Cell cycle protein
HPFPGLDM_00725	4.07e-160	mltD	-	CBM50	M	ko:K08307,ko:K12204,ko:K19224	-	ko00000,ko01000,ko01002,ko01011,ko02044	LysM domain
HPFPGLDM_00726	2.48e-315	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HPFPGLDM_00727	2.83e-261	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HPFPGLDM_00728	0.0	-	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Mur ligase middle domain
HPFPGLDM_00729	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HPFPGLDM_00730	0.0	-	3.4.16.4	-	M	ko:K03587	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011,ko03036	Penicillin-binding Protein dimerisation domain
HPFPGLDM_00732	0.0	rsmH	2.1.1.199	-	M	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HPFPGLDM_00733	4.54e-105	-	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HPFPGLDM_00734	4.33e-188	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
HPFPGLDM_00735	2.82e-154	-	-	-	S	-	-	-	UPF0126 domain
HPFPGLDM_00736	3.95e-13	-	-	-	S	-	-	-	Mac 1
HPFPGLDM_00737	8.31e-193	-	-	-	B	-	-	-	positive regulation of histone acetylation
HPFPGLDM_00739	5.68e-314	mnmE	-	-	J	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HPFPGLDM_00740	2.72e-263	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HPFPGLDM_00741	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase activity
HPFPGLDM_00742	3.45e-207	miaA	2.5.1.75	-	J	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HPFPGLDM_00743	6.92e-183	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
HPFPGLDM_00744	8.57e-272	-	-	-	S	ko:K11941	-	ko00000,ko01000	transferase activity, transferring acyl groups other than amino-acyl groups
HPFPGLDM_00745	3.73e-144	-	-	-	S	-	-	-	Hexapeptide repeat of succinyl-transferase
HPFPGLDM_00746	8.11e-284	-	-	-	M	-	-	-	Glycosyl transferases group 1
HPFPGLDM_00747	2.84e-289	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HPFPGLDM_00748	0.0	-	-	-	S	-	-	-	polysaccharide biosynthetic process
HPFPGLDM_00750	1.78e-240	-	-	-	H	-	-	-	PFAM glycosyl transferase family 8
HPFPGLDM_00751	2.19e-247	-	-	-	M	-	-	-	Glycosyl transferase, family 2
HPFPGLDM_00752	2.59e-255	MA20_42350	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	Glycosyl transferase, family 2
HPFPGLDM_00753	5.25e-282	-	1.8.1.2	-	P	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HPFPGLDM_00754	9.5e-239	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HPFPGLDM_00755	4.39e-244	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HPFPGLDM_00758	2.35e-129	-	-	-	-	-	-	-	-
HPFPGLDM_00759	1.23e-122	-	2.1.1.72	-	H	ko:K06223	ko03430,map03430	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	D12 class N6 adenine-specific DNA methyltransferase
HPFPGLDM_00768	0.0	-	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	transmembrane transport
HPFPGLDM_00770	5.95e-316	-	3.2.1.18	GH33	G	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	ko00000,ko00001,ko01000,ko02042	BNR/Asp-box repeat
HPFPGLDM_00771	2.28e-79	-	-	-	P	ko:K11741	-	ko00000,ko02000	Small Multidrug Resistance protein
HPFPGLDM_00772	0.0	-	6.3.5.1	-	H	ko:K01950	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	NAD synthase
HPFPGLDM_00773	3.99e-179	-	-	-	Q	-	-	-	methyltransferase activity
HPFPGLDM_00775	4.47e-137	-	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	Serine/threonine phosphatases, family 2C, catalytic domain
HPFPGLDM_00776	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase large chain, oligomerisation domain
HPFPGLDM_00777	1.03e-195	-	-	-	-	-	-	-	-
HPFPGLDM_00778	2e-120	-	3.2.2.28	-	L	ko:K03649	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	G/U mismatch-specific uracil-DNA glycosylase activity
HPFPGLDM_00779	2.56e-223	-	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III, delta subunit
HPFPGLDM_00780	4.98e-117	hisI	3.5.4.19	-	E	ko:K01496	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Phosphoribosyl-AMP cyclohydrolase
HPFPGLDM_00781	1.18e-170	-	-	-	S	ko:K05807	-	ko00000,ko02000	Outer membrane lipoprotein
HPFPGLDM_00782	7.51e-116	-	-	-	S	-	-	-	Lipopolysaccharide-assembly
HPFPGLDM_00783	4.83e-163	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Tetrapyrrole (Corrin/Porphyrin) Methylases
HPFPGLDM_00784	1.47e-178	-	-	-	S	-	-	-	Endonuclease/Exonuclease/phosphatase family
HPFPGLDM_00785	3.86e-18	-	-	-	-	-	-	-	-
HPFPGLDM_00786	6.46e-230	-	-	-	M	-	-	-	lytic endotransglycosylase activity
HPFPGLDM_00788	2.11e-272	-	-	-	S	-	-	-	regulation of ryanodine-sensitive calcium-release channel activity
HPFPGLDM_00790	3.28e-256	xerD1	-	-	L	ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
HPFPGLDM_00791	0.0	-	-	-	P	ko:K07221	-	ko00000,ko02000	Phosphate-selective porin O and P
HPFPGLDM_00792	3.86e-162	rnc	3.1.26.3	-	K	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HPFPGLDM_00793	1.07e-120	actI	1.5.1.36	-	S	ko:K00484	ko00350,ko00740,ko01100,ko01120,ko01220,map00350,map00740,map01100,map01120,map01220	ko00000,ko00001,ko01000	FMN binding
HPFPGLDM_00794	1.57e-259	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HPFPGLDM_00795	8.17e-147	-	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
HPFPGLDM_00796	1.89e-141	-	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Cytidylate kinase
HPFPGLDM_00797	0.0	-	-	-	I	-	-	-	Acetyltransferase (GNAT) domain
HPFPGLDM_00798	1.21e-209	thiL	2.7.4.16	-	H	ko:K00946	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HPFPGLDM_00799	4.34e-202	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HPFPGLDM_00800	0.0	-	-	-	GK	-	-	-	carbohydrate kinase activity
HPFPGLDM_00801	0.0	-	-	-	KLT	-	-	-	Protein tyrosine kinase
HPFPGLDM_00803	2.66e-290	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HPFPGLDM_00804	1.37e-129	-	-	-	D	ko:K06287	-	ko00000	Maf-like protein
HPFPGLDM_00805	0.0	-	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
HPFPGLDM_00808	1.53e-241	-	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Amidohydrolase
HPFPGLDM_00809	8.17e-159	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
HPFPGLDM_00810	1.48e-291	-	-	-	L	-	-	-	helicase superfamily c-terminal domain
HPFPGLDM_00811	1.71e-110	ruvC	3.1.22.4	-	L	ko:K01159	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
HPFPGLDM_00812	1.99e-121	-	-	-	-	-	-	-	-
HPFPGLDM_00813	0.0	sepA	-	-	Q	-	-	-	COG2015, Alkyl sulfatase and related hydrolases
HPFPGLDM_00814	2.21e-113	-	-	-	F	ko:K08311	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	NUDIX domain
HPFPGLDM_00815	4.91e-241	-	-	-	E	ko:K07588	-	ko00000,ko01000	ArgK protein
HPFPGLDM_00816	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycoside hydrolase, family 20, catalytic core
HPFPGLDM_00817	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycoside hydrolase, family 20, catalytic core
HPFPGLDM_00819	0.0	-	-	-	S	-	-	-	Phage portal protein, lambda family
HPFPGLDM_00820	1.28e-174	-	-	-	OU	ko:K04773	-	ko00000,ko01000,ko01002	Peptidase family S49
HPFPGLDM_00822	5.7e-198	-	-	-	-	-	-	-	-
HPFPGLDM_00829	0.0	-	-	-	D	-	-	-	nuclear chromosome segregation
HPFPGLDM_00835	1.52e-104	-	-	-	L	-	-	-	transposase and inactivated derivatives, IS30 family
HPFPGLDM_00836	0.0	-	-	-	S	-	-	-	Phage terminase large subunit (GpA)
HPFPGLDM_00837	7.98e-132	-	-	-	S	-	-	-	Glycosyl hydrolase 108
HPFPGLDM_00839	1.75e-115	-	-	-	S	-	-	-	Bacteriophage head to tail connecting protein
HPFPGLDM_00844	2.89e-174	-	6.3.5.11, 6.3.5.9	-	V	ko:K02224,ko:K18554	ko00860,ko01100,ko01120,map00860,map01100,map01120	br01600,ko00000,ko00001,ko01000,ko01504	Chloramphenicol phosphotransferase-like protein
HPFPGLDM_00845	6.71e-85	-	-	-	K	ko:K07343	-	ko00000	positive regulation of type IV pilus biogenesis
HPFPGLDM_00846	2.21e-231	-	-	-	CO	-	-	-	Redoxin
HPFPGLDM_00847	2.45e-123	paiA	-	-	K	-	-	-	acetyltransferase
HPFPGLDM_00848	7.13e-213	-	-	-	K	-	-	-	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen
HPFPGLDM_00850	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl tRNA synthetase N terminal dom
HPFPGLDM_00852	0.0	-	3.4.24.70	-	E	ko:K01414	-	ko00000,ko01000,ko01002	Peptidase family M3
HPFPGLDM_00853	0.0	-	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
HPFPGLDM_00854	1.69e-06	-	-	-	-	-	-	-	-
HPFPGLDM_00855	0.0	-	-	-	G	-	-	-	Glycosyl hydrolases family 18
HPFPGLDM_00856	0.0	-	-	-	S	ko:K07126,ko:K13582	ko04112,map04112	ko00000,ko00001	beta-lactamase activity
HPFPGLDM_00858	3.26e-276	-	6.2.1.26	-	IQ	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	AMP-binding enzyme
HPFPGLDM_00859	1.27e-70	-	-	-	K	-	-	-	ribonuclease III activity
HPFPGLDM_00860	1.14e-166	-	-	-	-	-	-	-	-
HPFPGLDM_00861	2.1e-140	nuoC	1.6.5.3	-	C	ko:K00332	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HPFPGLDM_00862	6.52e-139	nuoB	1.6.5.3	-	C	ko:K00331	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HPFPGLDM_00866	4.63e-90	-	-	-	M	-	-	-	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HPFPGLDM_00869	2.69e-90	-	-	-	K	-	-	-	BRO family, N-terminal domain
HPFPGLDM_00871	2.12e-78	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
HPFPGLDM_00872	9.2e-57	-	-	-	M	-	-	-	self proteolysis
HPFPGLDM_00873	4.22e-64	-	-	-	M	-	-	-	self proteolysis
HPFPGLDM_00875	5.31e-99	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HPFPGLDM_00876	2.76e-173	-	-	-	S	-	-	-	Lysin motif
HPFPGLDM_00877	3.5e-132	-	-	-	-	-	-	-	-
HPFPGLDM_00878	8.56e-45	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Phosphopantetheine attachment site
HPFPGLDM_00879	7.16e-174	coaX	2.7.1.33	-	K	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Type III pantothenate kinase
HPFPGLDM_00880	2.77e-272	-	-	-	M	-	-	-	Monogalactosyldiacylglycerol (MGDG) synthase
HPFPGLDM_00881	3.02e-227	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HPFPGLDM_00882	0.0	-	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	UvrD-like helicase C-terminal domain
HPFPGLDM_00884	0.0	-	-	-	S	ko:K03307	-	ko00000	Sodium:solute symporter family
HPFPGLDM_00885	1.26e-283	-	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Galactokinase galactose-binding signature
HPFPGLDM_00886	0.0	-	-	-	M	-	-	-	Bacterial sugar transferase
HPFPGLDM_00887	7.33e-143	-	-	-	S	-	-	-	RNA recognition motif
HPFPGLDM_00888	3.54e-185	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
HPFPGLDM_00889	0.0	-	-	-	-	-	-	-	-
HPFPGLDM_00891	0.0	-	-	-	V	-	-	-	ABC-2 type transporter
HPFPGLDM_00892	0.0	-	-	-	C	-	-	-	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein
HPFPGLDM_00893	1.63e-203	-	-	-	S	-	-	-	Domain of unknown function (DUF362)
HPFPGLDM_00894	1.49e-135	-	-	-	J	-	-	-	Putative rRNA methylase
HPFPGLDM_00895	2.35e-142	-	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HPFPGLDM_00896	3.73e-195	-	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease/Exonuclease/phosphatase family
HPFPGLDM_00897	5.58e-289	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	NusA-like KH domain
HPFPGLDM_00898	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HPFPGLDM_00899	2e-82	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HPFPGLDM_00900	0.0	-	-	-	P	-	-	-	PA14 domain
HPFPGLDM_00901	3.4e-15	-	-	-	-	-	-	-	-
HPFPGLDM_00902	2.27e-150	-	-	-	-	-	-	-	-
HPFPGLDM_00903	0.0	-	-	-	T	-	-	-	5TM C-terminal transporter carbon starvation CstA
HPFPGLDM_00904	0.0	-	-	-	EGIP	-	-	-	Phosphate acyltransferases
HPFPGLDM_00905	1.16e-134	-	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HPFPGLDM_00906	4.34e-284	-	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HPFPGLDM_00907	3.78e-228	-	-	-	C	-	-	-	e3 binding domain
HPFPGLDM_00908	3.93e-128	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
HPFPGLDM_00909	8.81e-265	-	-	-	S	-	-	-	PFAM glycosyl transferase family 2
HPFPGLDM_00910	1.37e-291	-	-	-	-	-	-	-	-
HPFPGLDM_00911	2.23e-259	-	-	-	S	-	-	-	Glycosyltransferase like family 2
HPFPGLDM_00912	7.21e-225	-	-	-	S	-	-	-	Glycosyl transferase family 11
HPFPGLDM_00913	1.15e-272	-	-	GT2	S	ko:K19427	-	ko00000,ko01000	PFAM glycosyl transferase family 2
HPFPGLDM_00915	1.76e-282	-	-	-	H	-	-	-	PFAM glycosyl transferase family 8
HPFPGLDM_00916	0.0	-	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Polyphosphate kinase middle domain
HPFPGLDM_00917	0.0	-	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	Ppx/GppA phosphatase family
HPFPGLDM_00918	3.1e-115	-	-	-	S	ko:K11941	-	ko00000,ko01000	transferase activity, transferring acyl groups other than amino-acyl groups
HPFPGLDM_00919	1.05e-111	-	-	-	S	ko:K11941	-	ko00000,ko01000	transferase activity, transferring acyl groups other than amino-acyl groups
HPFPGLDM_00920	1.29e-192	map	3.4.11.18	-	J	ko:K01265	-	ko00000,ko01000,ko01002	Metallopeptidase family M24
HPFPGLDM_00921	6.41e-155	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HPFPGLDM_00922	0.0	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HPFPGLDM_00924	6.42e-101	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A
HPFPGLDM_00925	3.38e-102	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HPFPGLDM_00926	2.38e-74	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HPFPGLDM_00927	2.25e-105	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HPFPGLDM_00928	4.08e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HPFPGLDM_00929	5.36e-138	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HPFPGLDM_00930	1.53e-47	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal proteins 50S L24/mitochondrial 39S L24
HPFPGLDM_00931	4.9e-207	nadK	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HPFPGLDM_00932	1.77e-124	-	-	-	M	ko:K03642	-	ko00000	Lytic transglycolase
HPFPGLDM_00933	0.0	-	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
HPFPGLDM_00934	0.0	-	2.7.11.1	-	L	ko:K08282	-	ko00000,ko01000	SNF2 Helicase protein
HPFPGLDM_00935	0.0	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HPFPGLDM_00937	1.53e-286	-	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Mur ligase middle domain
HPFPGLDM_00938	0.0	-	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Collagenase
HPFPGLDM_00940	0.0	rnr	-	-	K	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HPFPGLDM_00941	6.52e-75	-	-	-	L	-	-	-	Cupin 2, conserved barrel domain protein
HPFPGLDM_00942	7.1e-130	-	-	-	S	-	-	-	Cobalamin adenosyltransferase
HPFPGLDM_00944	3.03e-296	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HPFPGLDM_00945	4.75e-215	-	-	-	K	-	-	-	LysR substrate binding domain
HPFPGLDM_00946	1.17e-271	-	-	-	S	-	-	-	tRNA-splicing ligase RtcB
HPFPGLDM_00947	0.0	-	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	transmembrane transport
HPFPGLDM_00949	6.16e-285	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HPFPGLDM_00950	6.31e-134	-	-	-	D	-	-	-	ErfK ybiS ycfS ynhG family protein
HPFPGLDM_00951	0.0	-	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Aconitase C-terminal domain
HPFPGLDM_00952	8.8e-169	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	PFAM N-acetylmuramoyl-L-alanine amidase family 2
HPFPGLDM_00956	0.0	-	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	Bacterial DNA topoisomeraes I ATP-binding domain
HPFPGLDM_00957	1.35e-101	-	-	-	-	-	-	-	-
HPFPGLDM_00958	0.0	-	2.1.1.107, 4.2.1.75	-	H	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase HemD
HPFPGLDM_00959	2.24e-101	-	-	-	S	-	-	-	peptidase
HPFPGLDM_00960	5.18e-172	-	-	-	S	ko:K06973	-	ko00000	Putative neutral zinc metallopeptidase
HPFPGLDM_00961	2.1e-99	-	-	-	S	-	-	-	peptidase
HPFPGLDM_00962	0.0	-	-	-	S	-	-	-	pathogenesis
HPFPGLDM_00963	0.0	-	-	-	V	ko:K18095	ko01501,ko02020,map01501,map02020	ko00000,ko00001,ko00002,ko01504,ko02000	AcrB/AcrD/AcrF family
HPFPGLDM_00964	1.36e-240	-	-	-	M	ko:K18094	ko01501,ko02020,map01501,map02020	ko00000,ko00001,ko00002,ko01504,ko02000	Biotin-lipoyl like
HPFPGLDM_00965	2.07e-196	-	-	-	K	-	-	-	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
HPFPGLDM_00966	1.13e-221	-	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
HPFPGLDM_00967	9.47e-236	-	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, pyrimidine binding domain
HPFPGLDM_00968	1.63e-298	-	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	2-oxoacid dehydrogenases acyltransferase (catalytic domain)
HPFPGLDM_00969	8.16e-207	-	-	-	S	ko:K09949	-	ko00000	Protein of unknown function (DUF1009)
HPFPGLDM_00972	1.9e-90	-	-	-	-	-	-	-	-
HPFPGLDM_00973	2.14e-171	yyaQ	-	-	V	-	-	-	Protein conserved in bacteria
HPFPGLDM_00974	2.4e-190	-	-	-	M	-	-	-	Glycosyl transferase WecB/TagA/CpsF family
HPFPGLDM_00975	3.71e-190	-	3.1.4.55	-	S	ko:K06167	ko00440,map00440	ko00000,ko00001,ko01000	Metallo-beta-lactamase superfamily
HPFPGLDM_00976	0.0	-	-	-	L	ko:K03631	-	ko00000,ko03400	RecF/RecN/SMC N terminal domain
HPFPGLDM_00977	0.0	-	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
HPFPGLDM_00978	2.85e-245	-	-	-	G	-	-	-	Glycosyl hydrolases family 16
HPFPGLDM_00979	9.29e-132	-	-	-	J	ko:K02356	-	ko00000,ko03012	Elongation factor P (EF-P) OB domain
HPFPGLDM_00980	1.2e-105	-	-	-	S	-	-	-	ACT domain protein
HPFPGLDM_00981	4.8e-313	-	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
HPFPGLDM_00982	3.06e-85	-	-	-	M	ko:K03282	-	ko00000,ko02000	Large-conductance mechanosensitive channel, MscL
HPFPGLDM_00983	8.34e-277	-	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Alkaline phosphatase homologues
HPFPGLDM_00984	4.93e-286	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HPFPGLDM_00985	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycoside hydrolase, family 20, catalytic core
HPFPGLDM_00986	8.88e-268	-	-	-	G	-	-	-	M42 glutamyl aminopeptidase
HPFPGLDM_00988	1.96e-121	ngr	-	-	C	-	-	-	Rubrerythrin
HPFPGLDM_00990	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF1705)
HPFPGLDM_00991	0.0	-	-	-	M	-	-	-	Glycosyl Hydrolase Family 88
HPFPGLDM_00992	0.0	-	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Anaerobic ribonucleoside-triphosphate reductase
HPFPGLDM_00993	3.8e-43	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	CTP reductase activity
HPFPGLDM_00994	1.07e-188	-	1.97.1.4	-	O	ko:K04069	-	ko00000,ko01000	Radical SAM superfamily
HPFPGLDM_00995	0.0	-	-	-	P	ko:K14445	-	ko00000,ko02000	Citrate transporter
HPFPGLDM_00996	0.0	-	-	-	T	-	-	-	Histidine kinase
HPFPGLDM_00997	4.64e-111	-	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	cheY-homologous receiver domain
HPFPGLDM_00998	0.0	-	-	-	P	ko:K07085	-	ko00000	Predicted Permease Membrane Region
HPFPGLDM_00999	3.64e-25	-	-	-	M	ko:K13730	ko05100,map05100	ko00000,ko00001	leucine-rich repeat-containing protein typical subtype
HPFPGLDM_01003	8.41e-203	dapA	4.3.3.7	-	EM	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Dihydrodipicolinate synthetase family
HPFPGLDM_01004	4.14e-175	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Dihydrodipicolinate reductase, N-terminus
HPFPGLDM_01005	4.21e-121	-	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
HPFPGLDM_01006	4.13e-183	panB	2.1.2.11	-	H	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
HPFPGLDM_01007	5.87e-228	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
HPFPGLDM_01008	7.29e-211	-	-	-	M	-	-	-	Peptidase family M23
HPFPGLDM_01013	1.75e-110	-	-	-	S	-	-	-	Acetyltransferase (GNAT) family
HPFPGLDM_01014	1.48e-135	-	-	-	C	-	-	-	Nitroreductase family
HPFPGLDM_01016	0.0	-	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence
HPFPGLDM_01017	1.66e-87	-	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
HPFPGLDM_01018	8.8e-239	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HPFPGLDM_01019	1.39e-174	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	tRNA (Guanine-1)-methyltransferase
HPFPGLDM_01020	2.05e-28	-	-	-	-	-	-	-	-
HPFPGLDM_01021	2.55e-243	-	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	RNA pseudouridylate synthase
HPFPGLDM_01022	3.94e-243	-	-	-	S	-	-	-	PFAM Sel1 domain protein repeat-containing protein
HPFPGLDM_01023	8.48e-56	tatA	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HPFPGLDM_01024	0.0	-	-	-	J	ko:K07576	-	ko00000	Beta-Casp domain
HPFPGLDM_01025	1.55e-83	-	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	ArsC family
HPFPGLDM_01026	3.54e-181	-	-	-	P	ko:K10716	-	ko00000,ko02000	domain protein
HPFPGLDM_01027	0.0	-	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Carbohydrate phosphorylase
HPFPGLDM_01028	2.9e-258	tdh	1.1.1.103	-	E	ko:K00060	ko00260,map00260	ko00000,ko00001,ko01000	Alcohol dehydrogenase GroES-like domain
HPFPGLDM_01029	1.34e-161	-	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HPFPGLDM_01031	1.28e-181	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HPFPGLDM_01032	3.92e-115	-	-	-	-	-	-	-	-
HPFPGLDM_01036	0.0	-	-	-	L	-	-	-	DNA restriction-modification system
HPFPGLDM_01039	3.79e-166	-	-	-	S	-	-	-	PFAM Sel1 domain protein repeat-containing protein
HPFPGLDM_01041	6.08e-178	-	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HPFPGLDM_01043	1.81e-316	-	-	-	P	ko:K14445	-	ko00000,ko02000	Citrate transporter
HPFPGLDM_01044	0.0	-	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HPFPGLDM_01045	6.5e-266	mtrC	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HPFPGLDM_01046	0.0	-	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
HPFPGLDM_01048	0.0	-	-	-	G	-	-	-	alpha-galactosidase
HPFPGLDM_01051	0.0	poxB	1.2.3.3, 1.2.5.1	-	EH	ko:K00156,ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Thiamine pyrophosphate enzyme, central domain
HPFPGLDM_01052	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HPFPGLDM_01053	2.72e-183	-	-	-	L	ko:K10800	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	uracil-dna glycosylase
HPFPGLDM_01054	1.13e-228	-	2.7.1.11	-	G	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Phosphofructokinase
HPFPGLDM_01055	7.26e-269	-	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Male sterility protein
HPFPGLDM_01056	9.53e-206	-	2.7.7.24	-	M	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HPFPGLDM_01058	0.0	-	-	-	C	-	-	-	Acetyl-CoA hydrolase/transferase C-terminal domain
HPFPGLDM_01059	9.48e-192	-	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Biotin/lipoate A/B protein ligase family
HPFPGLDM_01060	0.0	-	4.1.1.3	-	C	ko:K01572	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	Na+-transporting oxaloacetate decarboxylase beta subunit
HPFPGLDM_01061	6.88e-55	-	-	-	I	-	-	-	PFAM biotin lipoyl attachment domain-containing protein
HPFPGLDM_01063	0.0	-	2.1.3.15, 6.4.1.3	-	I	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Carboxyl transferase domain
HPFPGLDM_01064	4.12e-100	-	5.1.99.1	-	E	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Glyoxalase-like domain
HPFPGLDM_01065	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
HPFPGLDM_01066	8.14e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HPFPGLDM_01068	7.62e-05	-	2.7.11.1, 2.7.11.17	-	T	ko:K08794,ko:K13412,ko:K17530	ko04626,ko04921,ko04925,ko05145,map04626,map04921,map04925,map05145	ko00000,ko00001,ko01000,ko01001	protein serine/threonine kinase activity
HPFPGLDM_01070	0.0	-	-	-	S	-	-	-	acetyltransferases and hydrolases with the alpha beta hydrolase fold
HPFPGLDM_01071	4.48e-297	-	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HPFPGLDM_01072	3.13e-114	-	-	-	P	-	-	-	Rhodanese-like domain
HPFPGLDM_01073	1.19e-152	-	-	-	S	-	-	-	Protein of unknown function (DUF1573)
HPFPGLDM_01074	2.92e-185	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	Signal peptidase (SPase) II
HPFPGLDM_01075	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HPFPGLDM_01076	2.03e-248	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HPFPGLDM_01077	1.89e-259	-	-	-	S	-	-	-	Peptidase family M28
HPFPGLDM_01078	0.0	-	3.2.1.51	GH95	G	ko:K15923	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65, N-terminal domain
HPFPGLDM_01079	4.81e-58	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HPFPGLDM_01080	2.27e-90	-	-	-	S	ko:K09793	-	ko00000	Protein of unknown function (DUF456)
HPFPGLDM_01081	5.86e-211	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
HPFPGLDM_01082	0.0	-	-	-	M	ko:K09808	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	MacB-like periplasmic core domain
HPFPGLDM_01083	4.56e-209	-	-	-	S	-	-	-	RDD family
HPFPGLDM_01084	1.25e-132	-	2.3.1.129	-	M	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	ko00000,ko00001,ko00002,ko01000,ko01005	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HPFPGLDM_01085	7.09e-166	-	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD-hyrolase-like
HPFPGLDM_01087	8.43e-283	-	-	-	S	ko:K09760	-	ko00000	RmuC family
HPFPGLDM_01088	0.0	-	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Transglycosylase
HPFPGLDM_01089	1.58e-239	-	-	-	O	-	-	-	Trypsin-like peptidase domain
HPFPGLDM_01090	5.88e-277	-	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
HPFPGLDM_01092	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HPFPGLDM_01094	3.69e-64	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HPFPGLDM_01095	9.92e-110	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HPFPGLDM_01096	4.97e-156	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HPFPGLDM_01097	2.58e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HPFPGLDM_01098	6.29e-135	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	In Spt5p, this domain may confer affinity for Spt4p. It possesses a RNP-like fold.
HPFPGLDM_01099	3.61e-46	-	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	SecE/Sec61-gamma subunits of protein translocation complex
HPFPGLDM_01101	9.94e-287	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HPFPGLDM_01103	6.13e-257	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HPFPGLDM_01104	0.0	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HPFPGLDM_01105	2.5e-153	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HPFPGLDM_01106	6.88e-281	tig	-	-	O	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HPFPGLDM_01107	0.0	-	-	-	M	ko:K07277	-	ko00000,ko02000,ko03029	Surface antigen
HPFPGLDM_01108	5.9e-156	-	1.14.11.27	-	P	ko:K10277	-	ko00000,ko01000,ko03036	peptidyl-arginine hydroxylation
HPFPGLDM_01109	2.6e-231	-	1.5.1.20	-	E	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Methylenetetrahydrofolate reductase
HPFPGLDM_01110	2.38e-169	-	-	-	CO	-	-	-	Protein conserved in bacteria
HPFPGLDM_01112	1.46e-147	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HPFPGLDM_01113	0.0	-	-	-	P	ko:K07239	-	ko00000	AcrB/AcrD/AcrF family
HPFPGLDM_01114	1.96e-297	czcB	-	-	M	ko:K15727	-	ko00000,ko02000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HPFPGLDM_01115	1.01e-293	-	-	-	MU	ko:K15725	-	ko00000,ko02000	efflux transmembrane transporter activity
HPFPGLDM_01117	3.17e-206	-	-	-	G	ko:K06867,ko:K07001	-	ko00000	response to abiotic stimulus
HPFPGLDM_01118	0.0	-	-	-	E	-	-	-	PFAM major facilitator superfamily MFS_1
HPFPGLDM_01121	3.9e-214	-	-	-	KQ	-	-	-	Hypothetical methyltransferase
HPFPGLDM_01122	3.77e-291	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HPFPGLDM_01123	0.0	ahcY	3.3.1.1	-	H	ko:K01251	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
HPFPGLDM_01124	3.65e-251	rgpB	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HPFPGLDM_01125	1.87e-248	-	-	-	-	-	-	-	-
HPFPGLDM_01126	0.0	-	-	-	H	-	-	-	Flavin containing amine oxidoreductase
HPFPGLDM_01127	8.66e-227	-	-	-	-	-	-	-	-
HPFPGLDM_01128	0.0	-	-	-	P	-	-	-	Domain of unknown function (DUF4976)
HPFPGLDM_01129	0.0	-	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	RecQ zinc-binding
HPFPGLDM_01131	3.86e-304	-	-	-	M	-	-	-	Glycosyl transferases group 1
HPFPGLDM_01132	9.76e-258	-	-	-	S	-	-	-	Glycoside-hydrolase family GH114
HPFPGLDM_01133	0.0	-	1.4.3.16	-	H	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Fumarate reductase flavoprotein C-term
HPFPGLDM_01134	2.86e-133	-	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	SpoU rRNA Methylase family
HPFPGLDM_01135	3.21e-206	-	3.1.1.53	-	L	ko:K03547,ko:K05970	-	ko00000,ko01000,ko03400	3'-5' exonuclease activity
HPFPGLDM_01136	9.94e-90	-	-	-	K	-	-	-	Helix-turn-helix diphteria tox regulatory element
HPFPGLDM_01137	0.0	-	-	-	P	-	-	-	E1-E2 ATPase
HPFPGLDM_01139	2.83e-303	-	-	-	M	ko:K07267	-	ko00000,ko02000	wide pore channel activity
HPFPGLDM_01143	0.0	-	-	-	P	ko:K04759	-	ko00000,ko02000	Ferrous iron transport protein B C terminus
HPFPGLDM_01144	4.02e-48	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	iron ion homeostasis
HPFPGLDM_01145	2.48e-40	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	iron ion homeostasis
HPFPGLDM_01146	0.0	-	1.11.1.5	-	P	ko:K00428	-	ko00000,ko01000	Di-haem cytochrome c peroxidase
HPFPGLDM_01147	5.44e-229	lipA	2.8.1.8	-	H	ko:K03644	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HPFPGLDM_01148	1.1e-131	tadA	3.5.4.33	-	FJ	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HPFPGLDM_01149	1.41e-241	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HPFPGLDM_01150	0.0	-	-	-	P	-	-	-	E1-E2 ATPase
HPFPGLDM_01151	0.0	-	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HPFPGLDM_01152	1.85e-142	coaE	2.7.1.24	-	H	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HPFPGLDM_01153	0.0	-	-	-	NU	ko:K02453	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02044	Bacterial type II and III secretion system protein
HPFPGLDM_01154	2.27e-245	-	-	-	-	-	-	-	-
HPFPGLDM_01155	8.68e-208	-	-	-	-	-	-	-	-
HPFPGLDM_01156	0.0	-	-	-	NU	-	-	-	Type IV pilus assembly protein PilM;
HPFPGLDM_01157	4.65e-168	-	-	-	-	-	-	-	-
HPFPGLDM_01158	1.14e-256	-	-	-	G	-	-	-	M42 glutamyl aminopeptidase
HPFPGLDM_01159	5.06e-261	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HPFPGLDM_01160	1.4e-155	-	-	-	S	-	-	-	Protein of unknown function (DUF3313)
HPFPGLDM_01161	8.33e-314	-	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	Aminopeptidase P, N-terminal domain
HPFPGLDM_01162	3.88e-207	hisG	2.4.2.17	-	E	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	ATP phosphoribosyltransferase
HPFPGLDM_01163	2.09e-10	-	-	-	S	-	-	-	Mitochondrial domain of unknown function (DUF1713)
HPFPGLDM_01168	4.25e-289	-	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
HPFPGLDM_01169	6.89e-168	-	-	-	T	ko:K07657	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
HPFPGLDM_01170	0.0	-	4.2.1.9	-	EG	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Dehydratase family
HPFPGLDM_01171	0.0	-	-	-	T	-	-	-	pathogenesis
HPFPGLDM_01172	1.64e-267	xerD1	-	-	L	ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
HPFPGLDM_01173	1.39e-206	-	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil DNA glycosylase superfamily
HPFPGLDM_01174	1.4e-287	-	4.1.99.19	-	H	ko:K03150	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Biotin and Thiamin Synthesis associated domain
HPFPGLDM_01175	0.0	-	-	-	M	-	-	-	Sulfatase
HPFPGLDM_01176	1.86e-291	-	-	-	-	-	-	-	-
HPFPGLDM_01177	0.0	-	3.2.1.51	GH95	G	ko:K15923	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65, N-terminal domain
HPFPGLDM_01178	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF2851)
HPFPGLDM_01179	1.29e-118	-	-	-	T	-	-	-	STAS domain
HPFPGLDM_01180	0.0	-	-	-	I	-	-	-	Prenyltransferase and squalene oxidase repeat
HPFPGLDM_01181	0.0	-	-	-	I	-	-	-	Prenyltransferase and squalene oxidase repeat
HPFPGLDM_01182	1.26e-247	-	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	NmrA-like family
HPFPGLDM_01183	0.0	-	2.1.1.182	-	IJ	ko:K02528	-	ko00000,ko01000,ko03009	Ribosomal RNA adenine dimethylases
HPFPGLDM_01184	5.07e-103	-	-	-	-	-	-	-	-
HPFPGLDM_01185	1.15e-52	-	-	-	-	-	-	-	-
HPFPGLDM_01186	9.56e-123	-	-	-	-	-	-	-	-
HPFPGLDM_01187	5.84e-299	-	-	-	V	ko:K03327	-	ko00000,ko02000	drug transmembrane transporter activity
HPFPGLDM_01188	0.0	-	-	-	P	-	-	-	Cation transport protein
HPFPGLDM_01191	2.66e-148	-	-	-	M	ko:K17733	-	ko00000,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
HPFPGLDM_01197	5.07e-263	-	-	GT4	M	ko:K16703	-	ko00000,ko01000,ko01003	transferase activity, transferring glycosyl groups
HPFPGLDM_01199	0.0	-	-	-	M	-	-	-	pathogenesis
HPFPGLDM_01210	3.01e-188	-	5.2.1.8	-	O	ko:K03773	-	ko00000,ko01000,ko03110	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase
HPFPGLDM_01211	5.35e-139	-	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HPFPGLDM_01212	8.59e-273	-	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	Thermophilic metalloprotease (M29)
HPFPGLDM_01213	2.54e-208	-	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
HPFPGLDM_01214	0.0	-	-	-	P	ko:K03455	-	ko00000	TrkA-N domain
HPFPGLDM_01215	1.2e-167	-	-	-	L	ko:K03424	-	ko00000,ko01000	TatD related DNase
HPFPGLDM_01221	1.33e-133	panZ	-	-	K	-	-	-	-acetyltransferase
HPFPGLDM_01222	1.96e-224	-	-	-	E	ko:K00612	-	ko00000,ko01000	lipolytic protein G-D-S-L family
HPFPGLDM_01223	1.02e-220	-	1.8.1.9	-	O	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Pyridine nucleotide-disulphide oxidoreductase
HPFPGLDM_01224	0.0	-	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase alpha chain
HPFPGLDM_01225	5.5e-176	-	-	-	-	-	-	-	-
HPFPGLDM_01227	3.89e-241	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HPFPGLDM_01228	3.2e-209	-	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Polyprenyl synthetase
HPFPGLDM_01229	1.39e-198	-	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Quinolinate phosphoribosyl transferase, N-terminal domain
HPFPGLDM_01230	3.45e-157	-	1.4.3.5	-	H	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)
HPFPGLDM_01231	1.6e-216	-	5.1.3.15	-	G	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Aldose 1-epimerase
HPFPGLDM_01232	0.0	-	-	-	G	-	-	-	Trehalase
HPFPGLDM_01233	0.0	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HPFPGLDM_01234	0.0	glnA	6.3.1.2	-	S	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HPFPGLDM_01235	1.1e-34	-	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L34
HPFPGLDM_01236	4.9e-76	-	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	Ribonuclease P
HPFPGLDM_01237	1.32e-60	-	-	-	S	ko:K08998	-	ko00000	Haemolytic
HPFPGLDM_01238	0.0	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins
HPFPGLDM_01239	0.0	-	1.4.1.13, 1.4.1.14	-	E	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	GXGXG motif
HPFPGLDM_01240	0.0	glnA	6.3.1.2	-	S	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HPFPGLDM_01241	0.0	-	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase large chain, oligomerisation domain
HPFPGLDM_01242	1.88e-273	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase small chain, CPSase domain
HPFPGLDM_01244	6.96e-265	-	4.2.1.47	-	M	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
HPFPGLDM_01245	2.53e-266	fcl	1.1.1.271	-	GM	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction
HPFPGLDM_01246	1.19e-295	-	-	-	C	-	-	-	Na+/H+ antiporter family
HPFPGLDM_01247	1.11e-236	-	-	-	-	-	-	-	-
HPFPGLDM_01248	1.39e-228	-	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphomannose isomerase type I
HPFPGLDM_01249	1.06e-180	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	PFAM N-acetylmuramoyl-L-alanine amidase family 2
HPFPGLDM_01250	5.31e-115	ispF	4.6.1.12	-	I	ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HPFPGLDM_01251	8.31e-186	-	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase family
HPFPGLDM_01252	0.0	-	-	-	M	-	-	-	PFAM glycosyl transferase family 51
HPFPGLDM_01253	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
HPFPGLDM_01254	2.17e-97	-	-	-	U	ko:K03559	-	ko00000,ko02000	Biopolymer transport protein ExbD/TolR
HPFPGLDM_01255	1.49e-181	-	-	-	U	ko:K03561	-	ko00000,ko02000	MotA/TolQ/ExbB proton channel family
HPFPGLDM_01256	0.0	-	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HPFPGLDM_01257	1.27e-99	-	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Predicted SPOUT methyltransferase
HPFPGLDM_01258	1.67e-86	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S9/S16
HPFPGLDM_01259	2.79e-97	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HPFPGLDM_01260	1.07e-30	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HPFPGLDM_01261	0.0	nnrD	4.2.1.136, 5.1.99.6	-	G	ko:K17758,ko:K17759	-	ko00000,ko01000	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HPFPGLDM_01262	1.69e-174	-	-	-	L	ko:K03630	-	ko00000	RadC-like JAB domain
HPFPGLDM_01264	1.15e-173	-	-	-	D	-	-	-	Phage-related minor tail protein
HPFPGLDM_01266	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HPFPGLDM_01267	8.25e-63	-	-	-	L	ko:K09747	-	ko00000	YbaB/EbfC DNA-binding family
HPFPGLDM_01268	1.89e-253	-	-	-	N	ko:K18353	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01504	Endonuclease Exonuclease Phosphatase
HPFPGLDM_01269	0.0	-	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	DHHA2
HPFPGLDM_01271	5.46e-189	-	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Orotidine 5'-phosphate decarboxylase / HUMPS family
HPFPGLDM_01272	0.0	-	-	-	S	-	-	-	OPT oligopeptide transporter protein
HPFPGLDM_01274	0.0	-	-	-	G	-	-	-	Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain
HPFPGLDM_01278	3.63e-13	-	-	-	L	-	-	-	Winged helix-turn helix
HPFPGLDM_01281	2.87e-102	-	-	-	D	ko:K03733	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
HPFPGLDM_01283	0.0	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
HPFPGLDM_01287	1.2e-51	-	-	-	L	ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
HPFPGLDM_01290	5.63e-177	-	-	-	O	-	-	-	Trypsin
HPFPGLDM_01291	8.14e-240	-	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
HPFPGLDM_01292	6.2e-203	-	-	-	-	-	-	-	-
HPFPGLDM_01293	0.0	-	-	-	S	-	-	-	Sulfatase-modifying factor enzyme 1
HPFPGLDM_01294	1.52e-281	-	-	-	S	-	-	-	Tetratricopeptide repeat
HPFPGLDM_01296	2.63e-10	-	-	-	-	-	-	-	-
HPFPGLDM_01298	8.23e-62	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HPFPGLDM_01299	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HPFPGLDM_01300	7.11e-228	-	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
HPFPGLDM_01301	4.38e-211	-	-	-	S	-	-	-	Protein of unknown function DUF58
HPFPGLDM_01302	1.98e-134	-	-	-	-	-	-	-	-
HPFPGLDM_01303	2.3e-229	-	-	-	S	-	-	-	Protein of unknown function (DUF1194)
HPFPGLDM_01305	8.51e-42	-	-	-	S	ko:K07114	-	ko00000,ko02000	von Willebrand factor (vWF) type A domain
HPFPGLDM_01306	0.0	-	-	-	S	-	-	-	Oxygen tolerance
HPFPGLDM_01307	1.16e-205	yeaE	-	-	S	-	-	-	aldo-keto reductase (NADP) activity
HPFPGLDM_01308	0.0	-	6.1.1.14	-	J	ko:K01880	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Anticodon binding domain
HPFPGLDM_01309	3.17e-157	-	-	-	S	-	-	-	DUF218 domain
HPFPGLDM_01310	1.93e-209	-	-	-	S	-	-	-	CAAX protease self-immunity
HPFPGLDM_01311	3.2e-286	-	-	-	E	ko:K10907	-	ko00000,ko01000,ko01007	Cys/Met metabolism PLP-dependent enzyme
HPFPGLDM_01312	8.26e-106	-	-	-	K	-	-	-	Lrp/AsnC ligand binding domain
HPFPGLDM_01313	0.0	-	-	-	L	-	-	-	SNF2 family N-terminal domain
HPFPGLDM_01314	8.46e-84	-	-	-	P	ko:K06195	-	ko00000	ApaG domain
HPFPGLDM_01315	2.23e-204	-	-	-	-	-	-	-	-
HPFPGLDM_01316	0.0	-	-	-	M	-	-	-	Glycosyl transferase family group 2
HPFPGLDM_01317	1.01e-190	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
HPFPGLDM_01318	1.88e-135	-	-	-	K	ko:K07735	-	ko00000,ko03000	Uncharacterized ACR, COG1678
HPFPGLDM_01319	2.91e-163	-	-	-	S	ko:K06997	-	ko00000	Alanine racemase, N-terminal domain
HPFPGLDM_01320	0.0	-	-	-	S	-	-	-	50S ribosome-binding GTPase
HPFPGLDM_01321	4.75e-138	-	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	5-formyltetrahydrofolate cyclo-ligase family
HPFPGLDM_01322	8.83e-209	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HPFPGLDM_01323	0.0	-	-	-	E	-	-	-	Peptidase dimerisation domain
HPFPGLDM_01324	3.12e-223	hprK	-	-	T	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr)
HPFPGLDM_01325	8.72e-53	-	-	-	G	ko:K11189	-	ko00000,ko02000	PTS HPr component phosphorylation site
HPFPGLDM_01326	0.0	-	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HPFPGLDM_01327	0.0	-	-	-	P	-	-	-	Sulfatase
HPFPGLDM_01328	1.64e-223	-	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HPFPGLDM_01329	5.06e-94	-	-	-	S	ko:K02426	-	ko00000	Fe-S metabolism associated domain
HPFPGLDM_01331	0.0	-	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Alpha amylase, C-terminal all-beta domain
HPFPGLDM_01332	5.05e-263	-	-	-	M	ko:K07271	-	ko00000,ko01000	LICD family
HPFPGLDM_01333	0.0	cobD	2.6.1.9, 2.7.7.74, 4.1.1.81	-	M	ko:K00817,ko:K04720,ko:K07281	ko00340,ko00350,ko00360,ko00400,ko00401,ko00562,ko00860,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00562,map00860,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	nucleotidyl transferase
HPFPGLDM_01334	5.29e-266	odh	1.5.1.28	-	I	ko:K04940	-	ko00000,ko01000	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
HPFPGLDM_01335	0.0	-	2.7.7.15	-	H	ko:K00968	ko00440,ko00564,ko01100,ko05231,map00440,map00564,map01100,map05231	ko00000,ko00001,ko00002,ko01000	Oxidoreductase family, NAD-binding Rossmann fold
HPFPGLDM_01336	7.29e-226	-	-	-	M	ko:K07271	-	ko00000,ko01000	LICD family
HPFPGLDM_01337	1.11e-128	-	-	-	S	-	-	-	protein trimerization
HPFPGLDM_01339	1.84e-183	-	2.1.1.144, 2.1.1.197	-	FG	ko:K00598,ko:K02169	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	trans-aconitate 2-methyltransferase activity
HPFPGLDM_01340	0.0	-	2.7.7.9	-	G	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP--glucose-1-phosphate uridylyltransferase
HPFPGLDM_01341	4.99e-125	-	-	-	-	-	-	-	-
HPFPGLDM_01342	1.12e-63	-	-	-	J	-	-	-	RF-1 domain
HPFPGLDM_01343	1.79e-122	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HPFPGLDM_01344	6.64e-279	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
HPFPGLDM_01345	1.18e-293	-	-	-	S	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
HPFPGLDM_01346	6.35e-47	-	-	-	K	ko:K18566	ko00332,ko01130,map00332,map01130	ko00000,ko00001,ko01000	acetyltransferase
HPFPGLDM_01347	1.15e-146	-	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HPFPGLDM_01348	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HPFPGLDM_01350	4.89e-237	-	4.2.1.24	-	H	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko04147	Delta-aminolevulinic acid dehydratase
HPFPGLDM_01352	2.04e-160	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
HPFPGLDM_01353	0.0	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
HPFPGLDM_01354	5.99e-231	-	4.1.1.35	-	M	ko:K08678	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko00002,ko01000	3-beta hydroxysteroid dehydrogenase/isomerase family
HPFPGLDM_01355	3.05e-183	-	-	-	I	-	-	-	Acyl-ACP thioesterase
HPFPGLDM_01356	2.87e-23	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
HPFPGLDM_01357	3.05e-192	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
HPFPGLDM_01360	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Prolyl-tRNA synthetase, C-terminal
HPFPGLDM_01361	2.04e-158	-	-	-	S	-	-	-	Peptidase family M50
HPFPGLDM_01363	6.79e-217	-	-	-	JM	-	-	-	Nucleotidyl transferase
HPFPGLDM_01364	8.25e-273	-	-	-	S	-	-	-	Phosphotransferase enzyme family
HPFPGLDM_01365	1.01e-222	-	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	NmrA-like family
HPFPGLDM_01367	0.0	-	-	-	L	ko:K07478	-	ko00000	MgsA AAA+ ATPase C terminal
HPFPGLDM_01368	1.38e-294	-	-	-	-	-	-	-	-
HPFPGLDM_01369	0.0	-	-	-	-	-	-	-	-
HPFPGLDM_01370	8.84e-140	mntP	-	-	P	-	-	-	manganese ion transmembrane transporter activity
HPFPGLDM_01372	9.06e-185	-	-	-	S	-	-	-	Phenazine biosynthesis-like protein
HPFPGLDM_01373	2.32e-176	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HPFPGLDM_01374	1.79e-316	-	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	Sigma-54 factor, Activator interacting domain (AID)
HPFPGLDM_01375	7.78e-273	ycaD	-	-	EGP	ko:K08219	-	ko00000,ko02000	Major facilitator Superfamily
HPFPGLDM_01376	1.6e-220	-	3.4.11.10, 3.4.11.6	-	DZ	ko:K19701	-	ko00000,ko01000,ko01002	aminopeptidase activity
HPFPGLDM_01377	6.98e-289	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
HPFPGLDM_01378	0.0	-	-	-	S	-	-	-	inositol 2-dehydrogenase activity
HPFPGLDM_01380	5.53e-285	-	3.6.4.13	-	L	ko:K11927	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	helicase superfamily c-terminal domain
HPFPGLDM_01382	4.21e-144	-	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	CDP-alcohol phosphatidyltransferase
HPFPGLDM_01383	0.0	-	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HPFPGLDM_01384	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
HPFPGLDM_01385	3.98e-277	-	4.2.1.51, 5.4.99.5	-	E	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Chorismate mutase type II
HPFPGLDM_01386	3.72e-237	-	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HPFPGLDM_01387	1.57e-190	-	-	-	S	-	-	-	NIF3 (NGG1p interacting factor 3)
HPFPGLDM_01388	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4340)
HPFPGLDM_01389	0.0	-	-	-	N	-	-	-	ABC-type uncharacterized transport system
HPFPGLDM_01390	2.49e-183	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HPFPGLDM_01391	1.09e-223	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HPFPGLDM_01392	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HPFPGLDM_01393	2.38e-133	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	nUDIX hydrolase
HPFPGLDM_01395	1.01e-251	-	2.3.1.1	-	E	ko:K14682	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Acetyltransferase (GNAT) family
HPFPGLDM_01396	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HPFPGLDM_01397	0.0	-	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HPFPGLDM_01402	2.21e-166	-	-	-	S	-	-	-	Terminase
HPFPGLDM_01406	8.96e-29	-	-	-	G	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HPFPGLDM_01407	8.29e-28	-	-	-	-	-	-	-	-
HPFPGLDM_01409	1.86e-37	-	-	-	KT	-	-	-	Peptidase S24-like
HPFPGLDM_01411	1.69e-107	-	-	-	K	-	-	-	DNA-binding transcription factor activity
HPFPGLDM_01412	4.2e-264	-	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Biotin-lipoyl like
HPFPGLDM_01413	0.0	-	-	-	V	-	-	-	AcrB/AcrD/AcrF family
HPFPGLDM_01414	5.02e-115	-	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Dihydrofolate reductase
HPFPGLDM_01415	5.77e-208	-	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Thymidylate synthase
HPFPGLDM_01416	0.0	-	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Phospholipase D. Active site motifs.
HPFPGLDM_01417	0.0	-	4.1.1.3	-	C	ko:K01571	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	HMGL-like
HPFPGLDM_01419	0.0	-	-	-	V	ko:K03327	-	ko00000,ko02000	MatE
HPFPGLDM_01420	1.23e-255	-	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Iron-sulfur cluster assembly protein
HPFPGLDM_01421	2.77e-41	-	-	-	S	-	-	-	PurA ssDNA and RNA-binding protein
HPFPGLDM_01423	0.0	-	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	LeuA allosteric (dimerisation) domain
HPFPGLDM_01424	0.0	prlC	3.4.24.70	-	E	ko:K01414	-	ko00000,ko01000,ko01002	Peptidase family M3
HPFPGLDM_01425	2.24e-282	-	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HPFPGLDM_01426	0.0	-	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HPFPGLDM_01427	0.0	-	-	-	MU	ko:K18139	ko01501,ko02024,map01501,map02024	ko00000,ko00001,ko00002,ko01504,ko02000	Outer membrane efflux protein
HPFPGLDM_01430	0.0	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
HPFPGLDM_01431	1.59e-150	-	-	-	-	-	-	-	-
HPFPGLDM_01434	1.34e-109	ptsN	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770,ko:K02806	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system
HPFPGLDM_01435	0.0	-	-	-	P	ko:K03281	-	ko00000	Voltage gated chloride channel
HPFPGLDM_01436	2.47e-253	-	-	-	L	-	-	-	Transposase IS200 like
HPFPGLDM_01437	0.0	-	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
HPFPGLDM_01438	8.24e-270	-	2.4.1.182	GT19	M	ko:K00748	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HPFPGLDM_01439	3.89e-149	dedA	-	-	S	-	-	-	FtsZ-dependent cytokinesis
HPFPGLDM_01440	6.7e-119	-	-	-	S	-	-	-	nitrogen fixation
HPFPGLDM_01446	5.01e-249	-	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	DnaB-like helicase C terminal domain
HPFPGLDM_01458	6.21e-39	-	-	-	-	-	-	-	-
HPFPGLDM_01459	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HPFPGLDM_01461	4.83e-232	-	-	-	CO	-	-	-	Thioredoxin-like
HPFPGLDM_01462	0.0	-	-	-	P	-	-	-	Domain of unknown function (DUF4976)
HPFPGLDM_01463	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycoside hydrolase, family 20, catalytic core
HPFPGLDM_01464	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class I (C) catalytic domain
HPFPGLDM_01465	1.87e-74	-	-	-	G	-	-	-	Cupin 2, conserved barrel domain protein
HPFPGLDM_01466	2.73e-209	ybfH	-	-	EG	-	-	-	spore germination
HPFPGLDM_01467	3.55e-127	-	-	-	-	-	-	-	-
HPFPGLDM_01468	0.0	-	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
HPFPGLDM_01469	3.62e-121	-	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HPFPGLDM_01470	7.48e-188	-	-	-	O	ko:K04083	-	ko00000,ko03110	Hsp33 protein
HPFPGLDM_01473	4.85e-232	-	-	-	E	-	-	-	PFAM lipolytic protein G-D-S-L family
HPFPGLDM_01477	1.69e-129	-	-	-	U	ko:K05595	-	ko00000,ko02000	MarC family integral membrane protein
HPFPGLDM_01478	5.94e-178	-	4.2.99.20	-	I	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Alpha/beta hydrolase family
HPFPGLDM_01479	1.46e-75	-	-	-	S	ko:K09954	-	ko00000	Putative quorum-sensing-regulated virulence factor
HPFPGLDM_01481	1.2e-49	-	-	-	-	-	-	-	-
HPFPGLDM_01482	4.19e-133	-	-	-	S	-	-	-	Protein of unknown function (DUF2589)
HPFPGLDM_01483	1.96e-184	-	-	-	-	-	-	-	-
HPFPGLDM_01484	2.59e-174	-	-	-	S	-	-	-	Protein of unknown function (DUF2589)
HPFPGLDM_01485	1.88e-111	-	-	-	KT	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	phosphorelay signal transduction system
HPFPGLDM_01486	6.4e-305	-	-	-	C	-	-	-	4 iron, 4 sulfur cluster binding
HPFPGLDM_01487	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
HPFPGLDM_01488	2.11e-219	-	-	-	K	-	-	-	Transcriptional regulator
HPFPGLDM_01489	4.25e-178	-	-	-	C	-	-	-	aldo keto reductase
HPFPGLDM_01490	2.92e-186	-	-	-	S	-	-	-	Alpha/beta hydrolase family
HPFPGLDM_01491	2.9e-275	-	-	-	S	ko:K06889	-	ko00000	X-Pro dipeptidyl-peptidase (S15 family)
HPFPGLDM_01492	9.66e-309	-	-	-	C	-	-	-	Carboxymuconolactone decarboxylase family
HPFPGLDM_01493	2.41e-158	-	-	-	IQ	-	-	-	Short chain dehydrogenase
HPFPGLDM_01494	6.36e-24	corC_1	-	-	P	ko:K03699	-	ko00000,ko02042	Transporter associated domain
HPFPGLDM_01496	4.21e-137	-	-	-	J	ko:K05808	-	ko00000,ko03009	Sigma 54 modulation/S30EA ribosomal protein C terminus
HPFPGLDM_01498	2.17e-08	-	-	-	M	-	-	-	major outer membrane lipoprotein
HPFPGLDM_01499	0.0	-	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
HPFPGLDM_01501	1.19e-168	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	KR domain
HPFPGLDM_01502	1.58e-307	-	-	-	C	-	-	-	Sulfatase-modifying factor enzyme 1
HPFPGLDM_01503	1.15e-40	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HPFPGLDM_01504	1.89e-50	-	-	-	-	-	-	-	-
HPFPGLDM_01505	5.1e-132	-	-	-	U	-	-	-	Protein of unknown function DUF262
HPFPGLDM_01507	1.15e-05	-	-	-	-	-	-	-	-
HPFPGLDM_01509	7.45e-49	XK27_09985	-	-	S	-	-	-	Protein of unknown function (DUF1232)
HPFPGLDM_01510	1.43e-194	-	-	-	S	ko:K07051	-	ko00000	TatD related DNase
HPFPGLDM_01511	8.94e-56	-	-	-	-	-	-	-	-
HPFPGLDM_01512	4.83e-163	-	-	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002	-
HPFPGLDM_01513	0.0	-	1.3.5.1, 1.3.5.4	-	C	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	Fumarate reductase flavoprotein C-term
HPFPGLDM_01514	1.29e-187	-	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	2Fe-2S iron-sulfur cluster binding domain
HPFPGLDM_01515	3.9e-201	-	-	GT4	M	ko:K16703	-	ko00000,ko01000,ko01003	transferase activity, transferring glycosyl groups
HPFPGLDM_01516	3.94e-90	-	-	-	M	-	-	-	pathogenesis
HPFPGLDM_01517	3.02e-116	-	-	-	F	-	-	-	SEFIR domain protein
HPFPGLDM_01518	3.74e-08	-	-	-	-	-	-	-	-
HPFPGLDM_01521	4.5e-255	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
HPFPGLDM_01524	1.21e-59	-	-	-	S	-	-	-	KAP family P-loop domain
HPFPGLDM_01528	8.84e-21	-	-	-	KL	-	-	-	CRISPR-associated helicase, Cas3
HPFPGLDM_01536	8.78e-29	-	-	-	-	-	-	-	-
HPFPGLDM_01539	5.06e-139	-	-	-	KLT	-	-	-	Protein kinase domain
HPFPGLDM_01540	3.44e-147	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
HPFPGLDM_01544	6.07e-08	-	-	-	V	-	-	-	N-6 DNA Methylase
HPFPGLDM_01545	7.45e-25	rela3	-	-	KT	-	-	-	Metal dependent phosphohydrolase
HPFPGLDM_01559	2.77e-72	-	-	-	S	-	-	-	Glycosyl hydrolase 108
HPFPGLDM_01561	2.22e-108	-	-	-	S	-	-	-	Bacteriophage head to tail connecting protein
HPFPGLDM_01563	1.42e-48	-	-	-	L	-	-	-	DNA N-6-adenine-methyltransferase (Dam)
HPFPGLDM_01566	4.96e-291	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
HPFPGLDM_01567	2.42e-194	-	-	-	KT	-	-	-	Peptidase S24-like
HPFPGLDM_01569	2.29e-141	-	-	-	M	-	-	-	polygalacturonase activity
HPFPGLDM_01570	2.41e-302	-	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase class I and II
HPFPGLDM_01571	1.91e-236	-	1.2.7.3	-	-	ko:K00176,ko:K07138	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	br01601,ko00000,ko00001,ko00002,ko01000	-
HPFPGLDM_01572	1.3e-205	-	-	-	S	-	-	-	Aldo/keto reductase family
HPFPGLDM_01573	9.93e-267	-	-	-	S	ko:K06889	-	ko00000	X-Pro dipeptidyl-peptidase (S15 family)
HPFPGLDM_01574	1.22e-269	-	-	-	C	-	-	-	Aldo/keto reductase family
HPFPGLDM_01575	3.6e-265	-	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase
HPFPGLDM_01576	9.98e-129	-	-	-	C	-	-	-	FMN binding
HPFPGLDM_01577	4.17e-102	-	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
HPFPGLDM_01578	6.4e-188	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Cupin domain
HPFPGLDM_01579	9.6e-105	-	-	-	S	-	-	-	Flavodoxin-like fold
HPFPGLDM_01580	7.97e-113	-	-	-	K	ko:K13640	-	ko00000,ko03000	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
HPFPGLDM_01581	1.65e-102	-	-	-	G	-	-	-	single-species biofilm formation
HPFPGLDM_01582	0.0	-	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
HPFPGLDM_01583	0.0	-	-	-	V	-	-	-	Polysaccharide biosynthesis C-terminal domain
HPFPGLDM_01585	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 20, domain 2
HPFPGLDM_01586	3.32e-241	-	4.2.1.113	-	M	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Mandelate Racemase Muconate Lactonizing
HPFPGLDM_01587	7.51e-217	-	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
HPFPGLDM_01588	0.0	-	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	RNA cap guanine-N2 methyltransferase
HPFPGLDM_01589	0.0	-	-	-	-	-	-	-	-
HPFPGLDM_01590	4.7e-57	-	-	-	S	ko:K06960	-	ko00000	KH domain
HPFPGLDM_01591	6.71e-285	-	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	S-adenosylmethionine-dependent methyltransferase
HPFPGLDM_01592	4.75e-214	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HPFPGLDM_01595	3.55e-174	-	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	FtsJ-like methyltransferase
HPFPGLDM_01597	1.51e-170	-	-	-	S	ko:K06911	-	ko00000	Pirin
HPFPGLDM_01598	0.0	-	-	-	M	-	-	-	AsmA-like C-terminal region
HPFPGLDM_01600	1.03e-201	-	-	-	G	-	-	-	Class II Aldolase and Adducin N-terminal domain
HPFPGLDM_01601	0.0	-	2.7.1.51	-	G	ko:K00879	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
HPFPGLDM_01602	0.0	fucI	5.3.1.25, 5.3.1.3	-	G	ko:K01818	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Converts the aldose L-fucose into the corresponding ketose L-fuculose
HPFPGLDM_01603	0.0	-	-	-	G	-	-	-	Major Facilitator Superfamily
HPFPGLDM_01604	1.03e-117	-	-	-	-	-	-	-	-
HPFPGLDM_01605	0.0	-	3.2.1.18	GH33	G	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	ko00000,ko00001,ko01000,ko02042	N-terminal domain of BNR-repeat neuraminidase
HPFPGLDM_01606	3.88e-133	-	-	-	K	ko:K03088	-	ko00000,ko03021	ECF sigma factor
HPFPGLDM_01607	7.29e-60	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	negative regulation of transcription, DNA-templated
HPFPGLDM_01608	0.0	copA	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
HPFPGLDM_01609	0.0	-	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	ThiC-associated domain
HPFPGLDM_01610	8.54e-218	ytpP	2.7.1.180, 5.3.4.1	-	CO	ko:K01829,ko:K03671,ko:K03734,ko:K06196	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko01000,ko02000,ko03110	cell redox homeostasis
HPFPGLDM_01611	1.07e-138	-	-	-	K	-	-	-	ECF sigma factor
HPFPGLDM_01613	1.42e-219	-	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
HPFPGLDM_01614	2.98e-233	-	-	-	O	-	-	-	Parallel beta-helix repeats
HPFPGLDM_01615	0.0	-	3.1.5.1	-	F	ko:K01129	ko00230,map00230	ko00000,ko00001,ko01000	Phosphohydrolase-associated domain
HPFPGLDM_01616	6.37e-283	-	-	-	Q	-	-	-	Multicopper oxidase
HPFPGLDM_01617	5.13e-213	-	-	-	EG	-	-	-	EamA-like transporter family
HPFPGLDM_01619	2.2e-274	-	5.1.1.1	-	M	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HPFPGLDM_01620	3.75e-243	-	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
HPFPGLDM_01621	9.42e-232	-	-	-	EP	ko:K02031	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
HPFPGLDM_01622	0.0	-	-	-	E	ko:K13893	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HPFPGLDM_01623	0.0	-	-	-	P	ko:K13895	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HPFPGLDM_01624	0.0	-	-	-	EP	ko:K13894	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HPFPGLDM_01625	1.4e-185	-	-	-	T	-	-	-	Calcineurin-like phosphoesterase superfamily domain
HPFPGLDM_01626	1.11e-206	-	-	-	S	-	-	-	Tetratricopeptide repeat
HPFPGLDM_01627	0.0	-	-	-	LO	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
HPFPGLDM_01628	7.15e-229	-	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Ketopantoate reductase PanE/ApbA C terminal
HPFPGLDM_01629	0.0	fhs	6.3.4.3	-	H	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Formate--tetrahydrofolate ligase
HPFPGLDM_01630	1.66e-144	-	-	-	S	ko:K09974	-	ko00000	Domain of unknown function (DUF1287)
HPFPGLDM_01631	1.13e-311	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain
HPFPGLDM_01632	3.77e-118	-	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-strand binding protein family
HPFPGLDM_01633	1.85e-283	-	5.4.99.22	-	M	ko:K06178	-	ko00000,ko01000,ko03009	translation initiation factor activity
HPFPGLDM_01634	4.44e-134	-	-	-	U	ko:K03561	-	ko00000,ko02000	MotA/TolQ/ExbB proton channel family
HPFPGLDM_01635	7.4e-93	-	-	-	U	ko:K03559	-	ko00000,ko02000	Biopolymer transport protein ExbD/TolR
HPFPGLDM_01636	8.02e-130	-	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HPFPGLDM_01637	8.59e-293	-	3.2.1.1	GH57	G	ko:K07405	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolase family 57
HPFPGLDM_01638	1.25e-315	-	-	-	G	-	-	-	Glycosyl transferase 4-like domain
HPFPGLDM_01639	0.0	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolases family 31
HPFPGLDM_01640	2.46e-249	-	5.4.4.2	-	HQ	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	chorismate binding enzyme
HPFPGLDM_01641	5.53e-313	-	-	-	C	ko:K00185	-	ko00000	Polysulphide reductase, NrfD
HPFPGLDM_01643	7.47e-156	-	-	-	C	-	-	-	Cytochrome c
HPFPGLDM_01644	4.3e-296	-	-	-	P	-	-	-	ABC-type Zn2 transport system, periplasmic component surface adhesin
HPFPGLDM_01645	0.0	-	-	-	C	-	-	-	Cytochrome c
HPFPGLDM_01647	2.38e-52	-	-	-	E	ko:K07032	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HPFPGLDM_01648	9.26e-270	-	-	-	S	-	-	-	Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units
HPFPGLDM_01649	5.54e-306	-	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Isocitrate/isopropylmalate dehydrogenase
HPFPGLDM_01650	3.02e-160	-	-	-	S	-	-	-	Protein of unknown function (DUF4230)
HPFPGLDM_01651	1.23e-62	-	-	-	S	-	-	-	Protein of unknown function (DUF1232)
HPFPGLDM_01652	0.0	-	-	-	J	-	-	-	Beta-Casp domain
HPFPGLDM_01653	9.88e-145	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HPFPGLDM_01654	1.02e-159	queC	6.3.4.20	-	F	ko:K06920	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Queuosine biosynthesis protein QueC
HPFPGLDM_01655	1.78e-97	queF	1.7.1.13	-	S	ko:K09457	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	QueF-like protein
HPFPGLDM_01656	0.0	kefA	-	-	M	ko:K05802,ko:K22051	-	ko00000,ko02000	cellular water homeostasis
HPFPGLDM_01657	0.0	gltX	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HPFPGLDM_01658	3.03e-237	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HPFPGLDM_01659	1.18e-190	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Bacitracin resistance protein BacA
HPFPGLDM_01662	8.99e-86	-	-	-	S	ko:K06940	-	ko00000	Putative zinc- or iron-chelating domain
HPFPGLDM_01663	2.69e-314	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HPFPGLDM_01664	4.73e-303	-	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
HPFPGLDM_01665	1.33e-52	-	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HPFPGLDM_01666	1.25e-261	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HPFPGLDM_01668	8.29e-100	cysJ	1.8.1.2	-	C	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	hydroxylamine reductase activity
HPFPGLDM_01670	8.49e-202	lpxG	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase
HPFPGLDM_01671	1.06e-169	BT0174	-	-	C	ko:K04488	-	ko00000	iron-sulfur transferase activity
HPFPGLDM_01672	2.08e-240	BT0173	-	-	S	-	-	-	Psort location Cytoplasmic, score
HPFPGLDM_01674	3.31e-270	-	2.1.1.72	-	H	ko:K07318	-	ko00000,ko01000,ko02048	PFAM D12 class N6 adenine-specific DNA methyltransferase
HPFPGLDM_01675	1.93e-209	-	-	-	L	ko:K04763	-	ko00000,ko03036	Phage integrase, N-terminal SAM-like domain
HPFPGLDM_01680	4.85e-128	-	-	-	S	-	-	-	Glycosyl hydrolase 108
HPFPGLDM_01681	2.03e-38	-	-	-	L	-	-	-	Mu-like prophage protein gp29
HPFPGLDM_01684	2.58e-69	-	-	-	MP	-	-	-	regulation of cell-substrate adhesion
HPFPGLDM_01697	3.98e-125	dinD	-	-	S	ko:K14623	-	ko00000,ko03400	Psort location Cytoplasmic, score
HPFPGLDM_01699	0.0	-	-	-	S	-	-	-	Phosphoadenosine phosphosulfate reductase
HPFPGLDM_01700	3.45e-121	-	-	-	K	-	-	-	ParB domain protein nuclease
HPFPGLDM_01703	1.52e-114	-	-	-	L	-	-	-	Staphylococcal nuclease homologues
HPFPGLDM_01704	6.56e-246	-	-	-	M	-	-	-	Alginate lyase
HPFPGLDM_01707	7.17e-104	yciA	-	-	I	ko:K10806	ko01040,map01040	ko00000,ko00001,ko01000,ko01004	acyl-coa hydrolase
HPFPGLDM_01708	7.09e-316	hsrA	-	-	EGP	-	-	-	Major facilitator Superfamily
HPFPGLDM_01709	1.41e-289	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
HPFPGLDM_01710	2.07e-243	-	-	-	CH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
HPFPGLDM_01711	2.62e-180	-	-	-	CH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
HPFPGLDM_01712	0.0	-	3.2.1.23	-	G	ko:K01190,ko:K12308	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolases family 35
HPFPGLDM_01714	8.77e-158	-	-	-	C	-	-	-	Nitroreductase family
HPFPGLDM_01715	0.0	-	-	-	E	-	-	-	Transglutaminase-like
HPFPGLDM_01716	5.58e-110	-	-	-	S	-	-	-	Bacterial transferase hexapeptide (six repeats)
HPFPGLDM_01717	6.56e-112	-	-	-	S	ko:K08999	-	ko00000	Bifunctional nuclease
HPFPGLDM_01719	0.0	-	-	-	P	-	-	-	Citrate transporter
HPFPGLDM_01721	2.8e-258	-	-	-	S	-	-	-	Glycosyltransferase family 10 (fucosyltransferase) C-term
HPFPGLDM_01722	0.0	-	-	-	I	-	-	-	Acyltransferase family
HPFPGLDM_01723	1.05e-252	-	-	-	S	-	-	-	Glycosyltransferase family 10 (fucosyltransferase) C-term
HPFPGLDM_01724	1.23e-310	-	-	-	M	-	-	-	Glycosyl transferases group 1
HPFPGLDM_01725	1.03e-204	-	-	-	-	-	-	-	-
HPFPGLDM_01726	2.25e-287	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HPFPGLDM_01727	2.26e-245	-	5.1.3.20	-	M	ko:K03274	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	3-beta hydroxysteroid dehydrogenase/isomerase family
HPFPGLDM_01728	5.25e-233	-	-	GT9	M	ko:K02843,ko:K02849	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	ADP-heptose-lipopolysaccharide heptosyltransferase activity
HPFPGLDM_01729	4.78e-249	-	-	-	S	-	-	-	Glycosyltransferase like family 2
HPFPGLDM_01730	9.15e-244	-	-	-	H	-	-	-	PFAM glycosyl transferase family 8
HPFPGLDM_01731	1.08e-209	lpxG	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase
HPFPGLDM_01733	8.48e-241	-	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain
HPFPGLDM_01734	9.36e-171	truB	5.4.99.25	-	J	ko:K03177	-	ko00000,ko01000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HPFPGLDM_01735	1.27e-222	-	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin kinase
HPFPGLDM_01736	9e-65	panD	4.1.1.11	-	H	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HPFPGLDM_01737	3.86e-76	-	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase SecG subunit
HPFPGLDM_01738	1.15e-151	-	-	-	NU	-	-	-	Prokaryotic N-terminal methylation motif
HPFPGLDM_01739	6.87e-256	-	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HPFPGLDM_01740	2.14e-127	-	-	-	-	-	-	-	-
HPFPGLDM_01741	5.05e-233	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HPFPGLDM_01742	9.68e-172	-	-	-	S	-	-	-	NYN domain
HPFPGLDM_01743	4.52e-153	ppaX_1	3.1.3.18, 3.6.1.1	-	S	ko:K01091,ko:K06019	ko00190,ko00630,ko01100,ko01110,ko01130,map00190,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	glycolate biosynthetic process
HPFPGLDM_01744	1.58e-138	-	-	-	S	-	-	-	Maltose acetyltransferase
HPFPGLDM_01745	0.0	-	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	GMP synthase C terminal domain
HPFPGLDM_01746	0.0	-	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	IMP dehydrogenase / GMP reductase domain
HPFPGLDM_01747	3.5e-121	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Low molecular weight phosphatase family
HPFPGLDM_01748	1.7e-227	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
HPFPGLDM_01752	3.68e-05	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HPFPGLDM_01753	7.13e-276	-	-	-	G	-	-	-	Major Facilitator Superfamily
HPFPGLDM_01754	9.11e-84	nuoA	1.6.5.3	-	C	ko:K00330	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HPFPGLDM_01756	3.96e-197	supH	-	-	Q	-	-	-	phosphatase activity
HPFPGLDM_01757	0.0	legA	3.5.1.2	-	G	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	response to abiotic stimulus
HPFPGLDM_01758	0.0	-	-	-	EG	-	-	-	BNR repeat-like domain
HPFPGLDM_01759	4.49e-187	-	-	-	E	-	-	-	PFAM lipolytic protein G-D-S-L family
HPFPGLDM_01761	3.43e-190	-	-	-	E	-	-	-	PFAM lipolytic protein G-D-S-L family
HPFPGLDM_01762	0.0	-	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
HPFPGLDM_01763	1.35e-191	-	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	4Fe-4S single cluster domain
HPFPGLDM_01764	0.0	-	2.3.1.241	-	M	ko:K02517	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Glycosyltransferase family 9 (heptosyltransferase)
HPFPGLDM_01765	3.75e-64	-	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L36
HPFPGLDM_01766	1.87e-292	-	2.3.1.31	-	E	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko01000	alpha/beta hydrolase fold
HPFPGLDM_01767	2.25e-91	-	-	-	O	-	-	-	response to oxidative stress
HPFPGLDM_01768	0.0	-	-	-	T	-	-	-	pathogenesis
HPFPGLDM_01770	9.44e-189	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HPFPGLDM_01771	2.08e-286	-	4.2.1.20	-	E	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HPFPGLDM_01772	2.94e-155	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	N-(5'phosphoribosyl)anthranilate (PRA) isomerase
HPFPGLDM_01773	1.67e-177	-	4.1.1.48	-	E	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Indole-3-glycerol phosphate synthase
HPFPGLDM_01774	0.0	trpD	2.4.2.18, 4.1.3.27	-	E	ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HPFPGLDM_01775	0.0	-	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Anthranilate synthase component I, N terminal region
HPFPGLDM_01779	0.0	hppA	3.6.1.1	-	C	ko:K15987	ko00190,map00190	ko00000,ko00001,ko01000	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane
HPFPGLDM_01780	4.06e-244	-	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo/keto reductase family
HPFPGLDM_01781	1.4e-182	-	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Biotin/lipoate A/B protein ligase family
HPFPGLDM_01782	1.04e-246	-	-	-	NU	-	-	-	Prokaryotic N-terminal methylation motif
HPFPGLDM_01783	1.83e-188	-	-	-	-	-	-	-	-
HPFPGLDM_01784	1.38e-174	-	-	-	NU	ko:K02457,ko:K08084	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02044	protein transport across the cell outer membrane
HPFPGLDM_01785	2.01e-243	-	-	-	S	-	-	-	Endonuclease/Exonuclease/phosphatase family
HPFPGLDM_01786	6.91e-165	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70 region 2
HPFPGLDM_01787	0.0	-	-	-	KT	-	-	-	Sigma factor PP2C-like phosphatases
HPFPGLDM_01788	9.77e-296	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HPFPGLDM_01789	0.0	-	-	-	M	-	-	-	Peptidase M60-like family
HPFPGLDM_01790	1.8e-215	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HPFPGLDM_01791	5.55e-306	-	-	-	M	-	-	-	OmpA family
HPFPGLDM_01792	2.1e-269	-	-	-	E	-	-	-	serine-type peptidase activity
HPFPGLDM_01793	3.56e-285	-	-	-	S	ko:K11720	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Predicted permease YjgP/YjgQ family
HPFPGLDM_01794	6.65e-169	-	-	-	S	-	-	-	HAD-hyrolase-like
HPFPGLDM_01796	4.4e-217	-	2.3.1.39	-	I	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Acyl transferase domain
HPFPGLDM_01797	4.19e-87	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HPFPGLDM_01798	2.95e-262	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HPFPGLDM_01799	2.38e-258	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Possible lysine decarboxylase
HPFPGLDM_01800	1.14e-278	-	3.4.23.43	-	NOU	ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	Type IV leader peptidase family
HPFPGLDM_01802	0.0	secD	-	-	U	ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HPFPGLDM_01803	4.62e-225	-	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
HPFPGLDM_01804	1.82e-172	-	-	-	T	-	-	-	Outer membrane lipoprotein-sorting protein
HPFPGLDM_01805	1.51e-164	-	-	-	S	ko:K05810	-	ko00000,ko01000	Multi-copper polyphenol oxidoreductase laccase
HPFPGLDM_01806	3.21e-217	-	-	-	-	-	-	-	-
HPFPGLDM_01808	5.46e-170	-	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Type I 3-dehydroquinase
HPFPGLDM_01809	1.79e-216	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
HPFPGLDM_01812	1.08e-208	-	-	-	J	ko:K01894	-	ko00000,ko01000,ko01007,ko03016	tRNA synthetases class I (E and Q), catalytic domain
HPFPGLDM_01813	0.0	-	-	-	P	-	-	-	Citrate transporter
HPFPGLDM_01814	1.47e-143	-	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase homologues.
HPFPGLDM_01815	8.27e-193	-	-	-	S	-	-	-	Domain of unknown function (DUF1732)
HPFPGLDM_01816	0.0	-	2.6.1.66	-	E	ko:K00835	ko00290,ko01100,ko01110,ko01130,map00290,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko01007	Aminotransferase class I and II
HPFPGLDM_01819	6.14e-235	-	-	-	CO	-	-	-	Protein of unknown function, DUF255
HPFPGLDM_01820	1.52e-173	zupT	-	-	P	ko:K07238	-	ko00000,ko02000	transporter
HPFPGLDM_01821	4e-257	-	-	-	L	-	-	-	Membrane
HPFPGLDM_01822	1.28e-253	-	2.7.1.11, 2.7.1.90	-	G	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Phosphofructokinase
HPFPGLDM_01823	9.66e-224	-	-	-	M	-	-	-	D-alanyl-D-alanine carboxypeptidase
HPFPGLDM_01826	1.47e-210	-	1.1.1.262	-	H	ko:K00097	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Pyridoxal phosphate biosynthetic protein PdxA
HPFPGLDM_01827	1.56e-60	-	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Ribosomal protein S6
HPFPGLDM_01828	1.31e-147	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HPFPGLDM_01829	1.48e-141	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Imidazoleglycerol-phosphate dehydratase
HPFPGLDM_01831	5.05e-131	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HPFPGLDM_01832	4.58e-220	prs	2.7.6.1	-	EF	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HPFPGLDM_01833	1.19e-229	-	-	-	C	-	-	-	Transmembrane exosortase (Exosortase_EpsH)
HPFPGLDM_01834	1.51e-174	-	-	-	S	-	-	-	Protein of unknown function (DUF3485)
HPFPGLDM_01835	5.95e-167	pks6	-	-	Q	-	-	-	amino acid activation for nonribosomal peptide biosynthetic process
HPFPGLDM_01836	6.29e-151	-	-	-	-	-	-	-	-
HPFPGLDM_01837	0.0	-	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
HPFPGLDM_01838	0.0	-	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Peptidase S24-like
HPFPGLDM_01839	1.02e-228	-	2.5.1.32, 2.5.1.99	-	I	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Squalene/phytoene synthase
HPFPGLDM_01840	0.0	-	-	-	M	-	-	-	Parallel beta-helix repeats
HPFPGLDM_01841	1.71e-241	-	3.1.3.18	-	F	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD-hyrolase-like
HPFPGLDM_01842	1.82e-173	-	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HPFPGLDM_01843	1.2e-262	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HPFPGLDM_01844	1.72e-116	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HPFPGLDM_01845	3.65e-60	-	-	-	S	ko:K09131	-	ko00000	DUF167
HPFPGLDM_01846	4.5e-176	-	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidine biosynthesis protein
HPFPGLDM_01848	7.06e-249	-	-	-	-	-	-	-	-
HPFPGLDM_01849	1.14e-126	-	-	-	M	-	-	-	Polymer-forming cytoskeletal
HPFPGLDM_01850	1.7e-148	-	-	-	M	-	-	-	Polymer-forming cytoskeletal
HPFPGLDM_01851	0.0	-	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	ATPases associated with a variety of cellular activities
HPFPGLDM_01854	7.7e-31	-	-	-	S	ko:K07126	-	ko00000	Sel1-like repeats.
HPFPGLDM_01855	5.01e-111	-	-	-	S	-	-	-	Putative zinc- or iron-chelating domain
HPFPGLDM_01856	2.26e-306	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HPFPGLDM_01857	1.75e-254	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Semialdehyde dehydrogenase, NAD binding domain
HPFPGLDM_01859	0.0	-	-	-	ET	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
HPFPGLDM_01860	8.78e-167	-	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HPFPGLDM_01861	2.34e-65	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	adenylate kinase activity
HPFPGLDM_01863	2.63e-06	-	-	-	K	ko:K07075	-	ko00000	sequence-specific DNA binding
HPFPGLDM_01865	1.61e-79	-	-	-	L	-	-	-	Transposase and inactivated derivatives
HPFPGLDM_01866	1.67e-53	-	-	-	K	-	-	-	Abortive infection C-terminus
HPFPGLDM_01867	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
HPFPGLDM_01868	1.84e-170	-	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	RNA pseudouridylate synthase
HPFPGLDM_01869	1.07e-192	-	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	RNA pseudouridylate synthase
HPFPGLDM_01870	3.7e-153	-	1.5.1.34	-	C	ko:K10679	ko00633,ko01120,map00633,map01120	ko00000,ko00001,ko01000	Nitroreductase family
HPFPGLDM_01871	0.0	-	-	-	M	ko:K04744	-	ko00000,ko02000	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
HPFPGLDM_01872	0.0	-	-	-	M	-	-	-	NPCBM/NEW2 domain
HPFPGLDM_01873	0.0	-	-	-	G	-	-	-	Glycogen debranching enzyme
HPFPGLDM_01874	7.43e-231	-	1.1.1.37	-	C	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible oxidation of malate to oxaloacetate
HPFPGLDM_01875	0.0	-	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	UDP binding domain
HPFPGLDM_01879	7.69e-100	-	-	-	MP	-	-	-	regulation of cell-substrate adhesion
HPFPGLDM_01883	2.59e-75	-	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
HPFPGLDM_01884	4.73e-241	tilS	6.3.4.19	-	D	ko:K04075	-	ko00000,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HPFPGLDM_01885	1.4e-259	-	2.3.1.8	-	C	ko:K00625	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Phosphate acetyl/butaryl transferase
HPFPGLDM_01886	5.56e-214	-	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	PHP domain
HPFPGLDM_01888	4.26e-254	-	-	-	S	-	-	-	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
HPFPGLDM_01889	0.0	-	-	-	G	-	-	-	Major Facilitator Superfamily
HPFPGLDM_01890	2.29e-296	-	-	-	-	-	-	-	-
HPFPGLDM_01891	0.0	-	-	-	L	-	-	-	TRCF
HPFPGLDM_01892	0.0	-	-	-	S	ko:K07126	-	ko00000	beta-lactamase activity
HPFPGLDM_01893	0.0	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	myo-inosose-2 dehydratase activity
HPFPGLDM_01894	2.18e-246	-	-	-	-	-	-	-	-
HPFPGLDM_01895	4.06e-286	pgk	2.7.2.3	-	G	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Phosphoglycerate kinase
HPFPGLDM_01896	1.67e-249	-	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
HPFPGLDM_01897	4.46e-148	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HPFPGLDM_01899	3.37e-133	-	-	-	M	-	-	-	Polysaccharide biosynthesis/export protein
HPFPGLDM_01900	0.0	-	-	-	D	-	-	-	Chain length determinant protein
HPFPGLDM_01901	8.04e-298	-	-	-	-	-	-	-	-
HPFPGLDM_01905	0.0	-	-	-	P	ko:K03306	-	ko00000	phosphate transporter
HPFPGLDM_01906	7.54e-99	-	-	-	S	-	-	-	peptidase
HPFPGLDM_01907	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HPFPGLDM_01908	2.2e-61	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HPFPGLDM_01909	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	MreB/Mbl protein
HPFPGLDM_01910	0.0	-	-	-	M	-	-	-	Glycosyl transferase 4-like domain
HPFPGLDM_01911	1.62e-279	-	-	-	S	-	-	-	COG0790 FOG TPR repeat, SEL1 subfamily
HPFPGLDM_01912	1.25e-241	-	-	-	O	ko:K04655	-	ko00000	AIR synthase related protein, N-terminal domain
HPFPGLDM_01913	3.86e-262	-	-	-	O	ko:K04654	-	ko00000	Hydrogenase formation hypA family
HPFPGLDM_01914	2.74e-50	-	-	-	O	ko:K04653	-	ko00000	HupF/HypC family
HPFPGLDM_01915	0.0	-	-	-	O	ko:K04656	-	ko00000	HypF finger
HPFPGLDM_01916	1.44e-175	hypB	-	-	KO	ko:K04652	-	ko00000,ko03110	CobW/HypB/UreG, nucleotide-binding domain
HPFPGLDM_01917	3e-310	-	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Histidyl-tRNA synthetase
HPFPGLDM_01918	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HPFPGLDM_01922	9.45e-261	-	2.3.1.47	-	H	ko:K00652	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
HPFPGLDM_01923	1.78e-285	-	-	-	IQ	-	-	-	Beta-ketoacyl synthase, C-terminal domain
HPFPGLDM_01924	0.0	-	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	thiolester hydrolase activity
HPFPGLDM_01925	3.75e-287	-	-	-	S	-	-	-	Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units
HPFPGLDM_01926	1.34e-147	-	-	-	IQ	-	-	-	RmlD substrate binding domain
HPFPGLDM_01927	0.0	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	GcpE protein
HPFPGLDM_01928	0.0	-	-	-	M	-	-	-	Bacterial membrane protein, YfhO
HPFPGLDM_01929	6.16e-198	-	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HPFPGLDM_01930	4.03e-120	-	-	-	-	-	-	-	-
HPFPGLDM_01931	3.85e-194	-	2.7.8.8	-	I	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	CDP-alcohol phosphatidyltransferase
HPFPGLDM_01932	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HPFPGLDM_01933	1.37e-227	-	-	-	M	ko:K01993	-	ko00000	HlyD family secretion protein
HPFPGLDM_01934	0.0	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HPFPGLDM_01935	1.03e-243	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HPFPGLDM_01936	1.25e-245	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HPFPGLDM_01939	4.05e-302	nupG	-	-	G	ko:K03289,ko:K03301,ko:K08218,ko:K11537	ko01501,map01501	ko00000,ko00001,ko00002,ko02000	Major facilitator Superfamily
HPFPGLDM_01940	7.19e-260	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HPFPGLDM_01941	1.98e-109	msrB	1.8.4.11, 1.8.4.12	-	O	ko:K07305,ko:K12267	-	ko00000,ko01000	peptide-methionine (R)-S-oxide reductase activity
HPFPGLDM_01942	3.9e-306	-	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HPFPGLDM_01944	8.84e-146	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HPFPGLDM_01945	2.37e-46	-	-	-	J	-	-	-	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HPFPGLDM_01946	0.0	-	-	-	-	-	-	-	-
HPFPGLDM_01947	0.0	-	-	-	S	-	-	-	Sodium:neurotransmitter symporter family
HPFPGLDM_01948	3.6e-152	-	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	C-terminal domain of 1-Cys peroxiredoxin
HPFPGLDM_01949	3.46e-210	-	-	-	M	-	-	-	Mechanosensitive ion channel
HPFPGLDM_01950	1.88e-164	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Amino acid kinase family
HPFPGLDM_01951	2.53e-120	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HPFPGLDM_01952	9.17e-70	-	-	-	M	-	-	-	Polymer-forming cytoskeletal
HPFPGLDM_01953	1.7e-101	-	-	-	K	-	-	-	DNA-binding transcription factor activity
HPFPGLDM_01954	3.03e-231	-	-	-	J	-	-	-	Belongs to the universal ribosomal protein uS2 family
HPFPGLDM_01955	8.34e-228	-	-	-	L	-	-	-	Elongator protein 3, MiaB family, Radical SAM
HPFPGLDM_01956	1.3e-150	-	-	-	H	-	-	-	HD superfamily hydrolase involved in NAD metabolism
HPFPGLDM_01957	0.0	-	-	-	S	ko:K07263	-	ko00000,ko01000,ko01002	Insulinase (Peptidase family M16)
HPFPGLDM_01959	7.65e-101	-	-	-	M	ko:K06077	-	ko00000	Glycine zipper 2TM domain
HPFPGLDM_01960	8.74e-234	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Converts alpha-aldose to the beta-anomer
HPFPGLDM_01961	7.37e-140	-	-	-	P	ko:K02039	-	ko00000	PhoU domain
HPFPGLDM_01962	6.37e-186	-	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HPFPGLDM_01963	2.51e-220	-	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	PBP superfamily domain
HPFPGLDM_01964	0.0	pstC	-	-	P	ko:K02037,ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HPFPGLDM_01965	0.0	-	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HPFPGLDM_01966	1.19e-185	-	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HPFPGLDM_01967	3.97e-153	phoU	-	-	P	ko:K02039	-	ko00000	negative regulation of phosphate transmembrane transport
HPFPGLDM_01969	6.62e-280	-	-	-	J	-	-	-	PFAM Endoribonuclease L-PSP
HPFPGLDM_01970	0.0	-	-	-	C	-	-	-	cytochrome C peroxidase
HPFPGLDM_01971	0.0	-	-	-	U	-	-	-	Involved in the tonB-independent uptake of proteins
HPFPGLDM_01972	7.36e-20	-	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	COG0010 Arginase agmatinase formimionoglutamate hydrolase arginase family
HPFPGLDM_01973	3.56e-297	-	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase family U32
HPFPGLDM_01974	2.66e-147	-	-	-	C	-	-	-	lactate oxidation
HPFPGLDM_01975	0.0	-	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	DNA Topoisomerase IV
HPFPGLDM_01976	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HPFPGLDM_01978	6.25e-76	-	-	-	M	-	-	-	Peptidoglycan-binding domain 1 protein
HPFPGLDM_01987	0.0	-	-	-	S	ko:K07126	-	ko00000	beta-lactamase activity
HPFPGLDM_01988	1.06e-182	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	AAA domain
HPFPGLDM_01989	0.0	-	-	-	KLT	-	-	-	Sulfatase-modifying factor enzyme 1
HPFPGLDM_01990	3.77e-289	kbl	2.3.1.29	-	E	ko:K00639	ko00260,map00260	ko00000,ko00001,ko01000,ko01007	Aminotransferase class I and II
HPFPGLDM_01991	3.09e-122	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
HPFPGLDM_01992	4.75e-231	-	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
HPFPGLDM_01994	9.9e-121	-	-	-	-	-	-	-	-
HPFPGLDM_01995	1.01e-184	-	-	-	H	ko:K22132	-	ko00000,ko03016	ThiF family
HPFPGLDM_01996	1.45e-190	-	-	-	S	ko:K09769	-	ko00000	YmdB-like protein
HPFPGLDM_01997	1.56e-103	-	-	-	T	-	-	-	Universal stress protein family
HPFPGLDM_01998	2.41e-232	-	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class I (W and Y)
HPFPGLDM_01999	4.37e-205	-	-	-	GM	-	-	-	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HPFPGLDM_02000	3.69e-166	-	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
HPFPGLDM_02001	2.55e-94	-	-	-	S	ko:K09117	-	ko00000	Yqey-like protein
HPFPGLDM_02002	2.57e-223	-	-	-	CO	-	-	-	amine dehydrogenase activity
HPFPGLDM_02003	0.0	-	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	HMGL-like
HPFPGLDM_02004	8.91e-203	-	-	-	Q	-	-	-	Fumarylacetoacetate (FAA) hydrolase family
HPFPGLDM_02005	1.42e-74	-	-	-	P	ko:K03972	-	ko00000	Rhodanese Homology Domain
HPFPGLDM_02006	0.0	-	3.2.1.50	-	G	ko:K01205	ko00531,ko01100,ko04142,map00531,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko04147	Alpha-L-fucosidase
HPFPGLDM_02007	0.0	-	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	C-terminal, D2-small domain, of ClpB protein
HPFPGLDM_02008	8.21e-246	-	2.7.14.1	-	E	ko:K19405	-	ko00000,ko01000	ATP:guanido phosphotransferase, C-terminal catalytic domain
HPFPGLDM_02009	4.49e-125	-	-	-	S	ko:K19411	-	ko00000	UvrB/uvrC motif
HPFPGLDM_02010	1.56e-179	-	-	-	P	ko:K09819	-	ko00000,ko00002,ko02000	FecCD transport family
HPFPGLDM_02011	4.35e-192	-	-	-	P	ko:K09820	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HPFPGLDM_02012	4.11e-100	-	-	-	-	-	-	-	-
HPFPGLDM_02013	2.39e-228	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Zinc-uptake complex component A periplasmic
HPFPGLDM_02014	0.0	hyl	2.3.1.48, 3.2.1.169, 3.2.1.35	GH84	G	ko:K01197,ko:K15719	ko00531,ko01100,ko04931,map00531,map01100,map04931	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	beta-N-acetylhexosaminidase activity
HPFPGLDM_02015	0.0	-	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	DHHA1 domain
HPFPGLDM_02016	5.01e-164	-	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	HMGL-like
HPFPGLDM_02018	0.0	-	-	-	V	-	-	-	MatE
HPFPGLDM_02019	4.33e-161	menG	2.1.1.163, 2.1.1.201	-	Q	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	ubiE/COQ5 methyltransferase family
HPFPGLDM_02023	1.46e-198	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HPFPGLDM_02024	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HPFPGLDM_02025	2.01e-214	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HPFPGLDM_02026	3.95e-252	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HPFPGLDM_02028	7.09e-309	-	-	-	E	ko:K03310	-	ko00000	Sodium:alanine symporter family
HPFPGLDM_02029	2.43e-95	-	-	-	K	-	-	-	-acetyltransferase
HPFPGLDM_02030	8.6e-222	-	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Glutaminase
HPFPGLDM_02031	0.0	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	amino acid
HPFPGLDM_02032	1.94e-293	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
HPFPGLDM_02034	4.56e-115	-	-	-	CO	-	-	-	cell redox homeostasis
HPFPGLDM_02036	2.12e-180	-	-	-	-	-	-	-	-
HPFPGLDM_02038	0.0	-	-	-	S	-	-	-	Bacteriophage head to tail connecting protein
HPFPGLDM_02041	3.45e-145	-	-	-	-	-	-	-	-
HPFPGLDM_02042	1.71e-64	-	-	-	K	-	-	-	DNA-binding transcription factor activity
HPFPGLDM_02044	7.62e-284	-	-	-	S	-	-	-	Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units
HPFPGLDM_02045	0.0	-	1.2.1.88, 1.5.5.2	-	CE	ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko03000	Proline dehydrogenase
HPFPGLDM_02047	1.01e-45	-	-	-	S	-	-	-	R3H domain
HPFPGLDM_02048	0.0	-	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	Catalase
HPFPGLDM_02050	0.0	-	-	-	O	-	-	-	Cytochrome C assembly protein
HPFPGLDM_02051	1.08e-136	rbr	-	-	C	-	-	-	Rubrerythrin
HPFPGLDM_02052	5.35e-145	-	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HPFPGLDM_02054	0.0	-	-	-	D	ko:K03466	-	ko00000,ko03036	Ftsk_gamma
HPFPGLDM_02055	5.68e-180	-	-	-	M	ko:K01991	ko02026,map02026	ko00000,ko00001,ko02000	polysaccharide export
HPFPGLDM_02056	0.0	gumC	-	-	DM	ko:K16554	ko05111,map05111	ko00000,ko00001,ko02000	PFAM lipopolysaccharide biosynthesis protein
HPFPGLDM_02057	9.48e-165	-	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	protein tyrosine phosphatase activity
HPFPGLDM_02058	6.88e-176	-	-	-	M	-	-	-	Bacterial sugar transferase
HPFPGLDM_02059	1.2e-189	wbyL	-	GT2	M	ko:K13002	-	ko00000,ko01000,ko01003,ko01005	transferase activity, transferring glycosyl groups
HPFPGLDM_02060	1.47e-292	lsgC	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HPFPGLDM_02061	9.92e-286	lsgC	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HPFPGLDM_02062	7.9e-291	gtf1	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	transferase activity, transferring glycosyl groups
HPFPGLDM_02063	1.21e-241	-	-	-	-	-	-	-	-
HPFPGLDM_02064	4.54e-264	-	-	-	M	ko:K02847,ko:K13009	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	-O-antigen
HPFPGLDM_02065	1.52e-201	-	-	-	S	-	-	-	Glycosyl transferase family 11
HPFPGLDM_02066	3.38e-252	-	-	-	M	-	-	-	Glycosyl transferases group 1
HPFPGLDM_02067	5.46e-281	-	-	-	M	-	-	-	Glycosyl transferase 4-like domain
HPFPGLDM_02068	2.42e-281	lsgC	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HPFPGLDM_02069	0.0	-	-	-	-	-	-	-	-
HPFPGLDM_02070	2.67e-113	-	-	-	S	ko:K03818	-	ko00000,ko01000	maltose O-acetyltransferase activity
HPFPGLDM_02071	1.42e-209	-	-	-	M	-	-	-	PFAM glycosyl transferase family 2
HPFPGLDM_02072	1.16e-241	-	-	-	M	-	-	-	Glycosyl transferase, family 2
HPFPGLDM_02073	1.55e-39	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
HPFPGLDM_02074	8.91e-123	-	-	-	C	-	-	-	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HPFPGLDM_02075	0.0	-	-	-	S	-	-	-	polysaccharide biosynthetic process
HPFPGLDM_02076	1.05e-228	-	-	-	C	-	-	-	Nitroreductase family
HPFPGLDM_02077	0.0	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
HPFPGLDM_02079	3.57e-283	-	-	-	S	-	-	-	very-long-chain-acyl-CoA dehydrogenase activity
HPFPGLDM_02080	1.19e-92	-	5.1.3.29	-	G	ko:K02431	-	ko00000,ko01000	RbsD / FucU transport protein family
HPFPGLDM_02081	1.06e-300	-	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase class I and II
HPFPGLDM_02082	0.0	-	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class I (C) catalytic domain
HPFPGLDM_02083	0.0	menD	2.2.1.9	-	H	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HPFPGLDM_02085	7.34e-315	-	1.1.1.40	-	C	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Malic enzyme, NAD binding domain
HPFPGLDM_02086	0.0	-	-	-	I	ko:K06889,ko:K09914	-	ko00000	PFAM Prenyltransferase squalene oxidase
HPFPGLDM_02087	8.4e-231	exsH	3.2.1.178, 3.2.1.18, 3.2.1.52	GH16,GH20,GH33	G	ko:K01186,ko:K12373,ko:K20830	ko00511,ko00513,ko00520,ko00531,ko00600,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00600,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko02042,ko03110	xyloglucan:xyloglucosyl transferase activity
HPFPGLDM_02088	6.39e-260	-	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Glycosyl hydrolase family 3 N terminal domain
HPFPGLDM_02089	2.76e-129	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HPFPGLDM_02090	3.19e-159	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
HPFPGLDM_02091	0.0	yidC	-	-	O	ko:K03217,ko:K06872	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	serine-type endopeptidase activity
HPFPGLDM_02092	5.56e-269	-	-	-	H	-	-	-	Elongator protein 3, MiaB family, Radical SAM
HPFPGLDM_02094	2.56e-309	-	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Seryl-tRNA synthetase N-terminal domain
HPFPGLDM_02095	1.94e-272	-	-	-	E	-	-	-	Alcohol dehydrogenase GroES-like domain
HPFPGLDM_02097	4.08e-215	-	3.5.1.53	-	K	ko:K12251	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
HPFPGLDM_02098	3.82e-231	-	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
HPFPGLDM_02099	6.5e-215	-	-	-	S	-	-	-	Protein of unknown function DUF58
HPFPGLDM_02100	1.03e-132	-	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	Peptidyl-tRNA hydrolase
HPFPGLDM_02101	0.0	-	-	-	M	-	-	-	Transglycosylase
HPFPGLDM_02102	0.0	-	3.4.24.3	-	NU	ko:K01387	-	ko00000,ko01000,ko01002,ko02042	translation initiation factor activity
HPFPGLDM_02103	0.0	-	-	-	H	-	-	-	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HPFPGLDM_02104	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HPFPGLDM_02106	0.0	-	-	-	M	ko:K07267	-	ko00000,ko02000	wide pore channel activity
HPFPGLDM_02107	2.95e-299	-	1.12.99.6	-	C	ko:K06282	ko00633,ko01120,map00633,map01120	ko00000,ko00001,ko01000	NiFe/NiFeSe hydrogenase small subunit C-terminal
HPFPGLDM_02108	0.0	-	1.12.99.6	-	C	ko:K06281	ko00633,ko01120,map00633,map01120	ko00000,ko00001,ko01000	Nickel-dependent hydrogenase
HPFPGLDM_02109	6.23e-288	hyaC	-	-	C	ko:K03620	ko02020,map02020	ko00000,ko00001	Prokaryotic cytochrome b561
HPFPGLDM_02110	3.4e-126	-	-	-	C	ko:K03605	-	ko00000,ko01000,ko01002	Hydrogenase maturation protease
HPFPGLDM_02111	2.09e-76	-	-	-	C	ko:K04651	-	ko00000,ko03110	Hydrogenase/urease nickel incorporation, metallochaperone, hypA
HPFPGLDM_02113	1.37e-86	-	-	-	S	ko:K09940	-	ko00000	Domain of unknown function (DUF4870)
HPFPGLDM_02114	7.19e-179	-	-	-	M	-	-	-	NLP P60 protein
HPFPGLDM_02115	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycosyl hydrolase family 20, domain 2
HPFPGLDM_02116	8.43e-155	-	1.5.1.34	-	C	ko:K10679	ko00633,ko01120,map00633,map01120	ko00000,ko00001,ko01000	Nitroreductase family
HPFPGLDM_02117	5.93e-261	-	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
HPFPGLDM_02121	0.0	secD	-	-	U	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HPFPGLDM_02122	8.6e-250	-	-	-	S	ko:K11941	-	ko00000,ko01000	transferase activity, transferring acyl groups other than amino-acyl groups
HPFPGLDM_02123	0.0	-	4.2.1.2	-	C	ko:K01676	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible hydration of fumarate to (S)- malate
HPFPGLDM_02126	1.53e-107	-	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	6-pyruvoyl tetrahydropterin synthase
HPFPGLDM_02128	0.0	-	3.2.1.52	GH20	G	ko:K01207,ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko01501,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map01501,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycoside hydrolase, family 20, catalytic core
HPFPGLDM_02129	4.39e-302	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HPFPGLDM_02130	1.02e-228	-	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Quinolinate synthetase A protein
HPFPGLDM_02131	7.12e-255	-	-	-	S	-	-	-	Putative S-adenosyl-L-methionine-dependent methyltransferase
HPFPGLDM_02132	5.28e-56	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
HPFPGLDM_02137	4.13e-28	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
HPFPGLDM_02138	0.0	kdpA	3.6.3.12	-	P	ko:K01546	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
HPFPGLDM_02139	0.0	kdpB	3.6.3.12	-	P	ko:K01547	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
HPFPGLDM_02140	2.97e-131	kdpC	3.6.3.12	-	P	ko:K01548	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
HPFPGLDM_02142	1.58e-262	-	2.7.13.3	-	T	ko:K07646	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Osmosensitive K+ channel His kinase sensor domain
HPFPGLDM_02143	1.29e-235	-	2.7.11.1	-	T	ko:K08884,ko:K12132,ko:K20333	ko02024,map02024	ko00000,ko00001,ko01000,ko01001	PFAM Formylglycine-generating sulfatase enzyme
HPFPGLDM_02145	2.43e-204	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
HPFPGLDM_02146	6e-142	-	-	-	K	ko:K03088	-	ko00000,ko03021	DNA-templated transcription, initiation
HPFPGLDM_02147	0.0	-	-	-	KLT	-	-	-	Protein tyrosine kinase
HPFPGLDM_02148	1.02e-282	-	-	-	C	-	-	-	Aldo/keto reductase family
HPFPGLDM_02149	6.71e-90	-	-	-	K	-	-	-	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
HPFPGLDM_02150	4.92e-260	-	4.1.2.48	-	E	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Beta-eliminating lyase
HPFPGLDM_02151	1.7e-291	-	-	-	-	-	-	-	-
HPFPGLDM_02152	0.0	-	-	-	S	-	-	-	von Willebrand factor type A domain
HPFPGLDM_02153	0.0	-	-	-	S	-	-	-	Aerotolerance regulator N-terminal
HPFPGLDM_02154	6.44e-205	-	-	-	S	-	-	-	Protein of unknown function DUF58
HPFPGLDM_02155	0.0	-	-	-	S	-	-	-	ABC-type transport system involved in multi-copper enzyme maturation permease component
HPFPGLDM_02156	1.78e-241	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
HPFPGLDM_02157	0.0	-	-	-	-	-	-	-	-
HPFPGLDM_02158	3.51e-236	-	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
HPFPGLDM_02159	1.16e-33	-	-	-	S	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
HPFPGLDM_02160	8.88e-218	-	-	-	S	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
HPFPGLDM_02162	4.01e-240	-	-	-	E	-	-	-	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HPFPGLDM_02164	5.75e-202	-	-	-	O	-	-	-	stress-induced mitochondrial fusion
HPFPGLDM_02165	5.4e-207	-	-	-	S	ko:K07071	-	ko00000	Domain of unknown function (DUF1731)
HPFPGLDM_02166	1.72e-120	-	-	-	M	ko:K03098	-	ko00000,ko04147	Lipocalin-like domain
HPFPGLDM_02167	1.35e-236	-	1.1.1.86	-	E	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HPFPGLDM_02168	2.69e-185	-	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HPFPGLDM_02169	3.36e-153	-	-	-	K	-	-	-	Transcriptional regulator
HPFPGLDM_02171	0.0	-	-	-	P	-	-	-	Sulfatase
HPFPGLDM_02173	1.26e-79	divIC	-	-	D	ko:K05589,ko:K13052	-	ko00000,ko03036	cell cycle
HPFPGLDM_02174	4.6e-305	-	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HPFPGLDM_02175	3.59e-47	-	-	-	E	-	-	-	Aminotransferase class I and II
HPFPGLDM_02176	0.0	-	-	-	E	-	-	-	Aminotransferase class I and II
HPFPGLDM_02177	8.74e-220	-	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HPFPGLDM_02178	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Alpha galactosidase A
HPFPGLDM_02179	1.04e-49	-	-	-	-	-	-	-	-
HPFPGLDM_02180	1.45e-55	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L28 family
HPFPGLDM_02181	1.5e-232	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
HPFPGLDM_02182	2.13e-96	-	-	-	L	ko:K07447	-	ko00000,ko01000	Likely ribonuclease with RNase H fold.
HPFPGLDM_02183	2.41e-259	-	2.7.7.13	-	M	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
HPFPGLDM_02184	1.06e-173	-	2.5.1.31	-	I	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HPFPGLDM_02185	0.0	-	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	TopoisomeraseII
HPFPGLDM_02186	4.94e-210	ispE	2.7.1.148	-	I	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	GHMP kinases N terminal domain
HPFPGLDM_02188	0.0	-	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	HELICc2
HPFPGLDM_02189	4.82e-179	cbiO	-	-	P	ko:K02006,ko:K02008,ko:K16784,ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPase activity
HPFPGLDM_02190	2.42e-195	cbiQ	-	-	P	ko:K02007,ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transmembrane transporter activity
HPFPGLDM_02191	1.77e-238	cbiM	-	-	P	ko:K02007,ko:K02009,ko:K16915	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt ion transport
HPFPGLDM_02193	1.42e-18	-	-	-	S	-	-	-	Lipocalin-like
HPFPGLDM_02194	3.2e-209	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
HPFPGLDM_02195	1.05e-226	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HPFPGLDM_02196	1.06e-94	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L9, N-terminal domain
HPFPGLDM_02197	0.0	-	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	AICARFT/IMPCHase bienzyme
HPFPGLDM_02198	2.39e-174	pdxJ	2.6.99.2	-	H	ko:K03474	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HPFPGLDM_02199	2.13e-83	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	4'-phosphopantetheinyl transferase superfamily
HPFPGLDM_02201	0.0	pckG	4.1.1.32	-	C	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle
HPFPGLDM_02202	4.02e-166	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	PFAM N-acetylmuramoyl-L-alanine amidase family 2
HPFPGLDM_02203	0.0	-	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	RecG wedge domain
HPFPGLDM_02205	0.0	-	-	-	C	ko:K00184	-	ko00000	4Fe-4S dicluster domain
HPFPGLDM_02206	2.16e-180	-	-	-	C	-	-	-	Cytochrome c7 and related cytochrome c
HPFPGLDM_02207	0.0	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HPFPGLDM_02209	7.39e-254	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Iron-containing alcohol dehydrogenase
HPFPGLDM_02216	3.33e-12	-	-	-	D	-	-	-	Psort location OuterMembrane, score
HPFPGLDM_02226	2.62e-21	-	-	-	OU	-	-	-	Serine dehydrogenase proteinase
HPFPGLDM_02229	2.87e-71	-	-	-	S	-	-	-	Phage terminase large subunit (GpA)
HPFPGLDM_02233	8.2e-08	-	-	-	N	-	-	-	HicA toxin of bacterial toxin-antitoxin,
HPFPGLDM_02234	2.61e-18	-	-	-	N	-	-	-	PFAM Uncharacterised protein family UPF0150
HPFPGLDM_02238	1.29e-83	-	2.1.1.72	-	L	ko:K06223	ko03430,map03430	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	D12 class N6 adenine-specific DNA methyltransferase
HPFPGLDM_02242	1.12e-19	-	2.1.1.37	-	L	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
HPFPGLDM_02251	1.04e-54	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	thiamine diphosphate biosynthetic process
HPFPGLDM_02252	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HPFPGLDM_02253	0.0	-	-	-	M	ko:K02847,ko:K13009,ko:K16705	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	-O-antigen
HPFPGLDM_02254	8.67e-85	-	-	-	S	-	-	-	Protein of unknown function, DUF488
HPFPGLDM_02255	2.07e-235	-	2.5.1.61	-	H	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Porphobilinogen deaminase, dipyromethane cofactor binding domain
HPFPGLDM_02256	9.18e-242	hemA	1.2.1.70	-	H	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Glutamyl-tRNAGlu reductase, N-terminal domain
HPFPGLDM_02257	1.02e-178	-	-	-	S	-	-	-	Cytochrome C assembly protein
HPFPGLDM_02258	3.84e-189	folE2	3.5.4.16	-	S	ko:K09007	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Type I GTP cyclohydrolase folE2
HPFPGLDM_02259	4.52e-49	-	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S18
HPFPGLDM_02260	5.67e-33	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L33
HPFPGLDM_02261	1.46e-118	-	-	-	T	-	-	-	Prokaryotic dksA/traR C4-type zinc finger
HPFPGLDM_02262	5.9e-232	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HPFPGLDM_02263	1.36e-243	sun	2.1.1.176, 2.1.1.178	-	J	ko:K03500,ko:K11392	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HPFPGLDM_02264	5.33e-124	-	-	-	S	ko:K07095	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
HPFPGLDM_02265	2.34e-97	nudI	3.6.1.55	-	F	ko:K03574,ko:K12944	-	ko00000,ko01000,ko03400	GDP-mannose mannosyl hydrolase activity
HPFPGLDM_02267	4.76e-282	-	-	-	M	ko:K02005	-	ko00000	HlyD family secretion protein
HPFPGLDM_02268	2.12e-162	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HPFPGLDM_02269	3.42e-313	-	-	-	V	-	-	-	MacB-like periplasmic core domain
HPFPGLDM_02270	1.09e-315	-	-	-	MU	-	-	-	Outer membrane efflux protein
HPFPGLDM_02271	1.57e-284	-	-	-	V	-	-	-	Beta-lactamase
HPFPGLDM_02272	0.0	-	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HPFPGLDM_02273	1.8e-284	mtrC	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HPFPGLDM_02274	8.35e-94	-	-	-	K	-	-	-	DNA-binding transcription factor activity
HPFPGLDM_02275	1.39e-162	-	-	-	S	-	-	-	Uncharacterised protein family UPF0066
HPFPGLDM_02276	5.56e-306	-	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Dihydro-orotase-like
HPFPGLDM_02277	3.64e-221	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain
HPFPGLDM_02278	1.15e-122	-	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Phosphoribosyl transferase domain
HPFPGLDM_02279	3.73e-90	-	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	AIR carboxylase
HPFPGLDM_02281	0.0	-	-	-	H	ko:K07137	-	ko00000	5-formyltetrahydrofolate cyclo-ligase activity
HPFPGLDM_02282	4.36e-266	-	3.5.3.12	-	E	ko:K10536	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	Porphyromonas-type peptidyl-arginine deiminase
HPFPGLDM_02283	2.11e-89	-	-	-	-	-	-	-	-
HPFPGLDM_02284	0.0	rseP	3.4.21.116	-	M	ko:K06399,ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	metalloendopeptidase activity
HPFPGLDM_02285	1.12e-302	-	-	-	S	-	-	-	AI-2E family transporter
HPFPGLDM_02286	0.0	-	-	-	P	-	-	-	Domain of unknown function
HPFPGLDM_02288	1.13e-111	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
HPFPGLDM_02289	4.75e-314	-	-	-	G	-	-	-	cellulose 1,4-beta-cellobiosidase activity
HPFPGLDM_02290	4.02e-188	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HPFPGLDM_02292	1.83e-74	-	-	-	-	-	-	-	-
HPFPGLDM_02293	0.0	-	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	DNA Topoisomerase IV
HPFPGLDM_02295	4.5e-133	-	-	-	S	-	-	-	Glycosyl hydrolase 108
HPFPGLDM_02299	1.24e-200	-	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	ParB-like nuclease domain
HPFPGLDM_02300	2.41e-233	-	-	-	S	-	-	-	Peptidase family M28
HPFPGLDM_02301	0.0	-	-	-	M	-	-	-	Aerotolerance regulator N-terminal
HPFPGLDM_02302	0.0	-	-	-	S	-	-	-	Large extracellular alpha-helical protein
HPFPGLDM_02305	7.79e-236	-	-	-	S	ko:K14347	-	ko00000,ko02000,ko04147	SBF-like CPA transporter family (DUF4137)
HPFPGLDM_02306	6.48e-273	-	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	tRNA synthetases class I (W and Y)
HPFPGLDM_02308	3.51e-85	-	-	-	S	ko:K09922	-	ko00000	Putative member of DMT superfamily (DUF486)
HPFPGLDM_02309	1.6e-213	-	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	N-terminal TM domain of oligopeptide transport permease C
HPFPGLDM_02310	1.6e-217	-	-	-	EP	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HPFPGLDM_02311	0.0	-	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HPFPGLDM_02312	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
HPFPGLDM_02313	5.12e-218	-	-	-	O	-	-	-	Thioredoxin-like domain
HPFPGLDM_02314	6.5e-311	-	1.5.1.7	-	E	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Saccharopine dehydrogenase C-terminal domain
HPFPGLDM_02315	1.18e-233	-	-	-	S	ko:K01128	-	ko00000,ko01000	acid phosphatase activity
HPFPGLDM_02319	0.0	-	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Tubulin/FtsZ family, GTPase domain
HPFPGLDM_02320	3.38e-294	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HPFPGLDM_02321	1.72e-147	-	-	-	M	-	-	-	NLP P60 protein
HPFPGLDM_02322	0.0	-	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III
HPFPGLDM_02323	0.0	-	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter transmembrane region
HPFPGLDM_02324	0.0	-	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter transmembrane region
HPFPGLDM_02325	0.0	-	-	-	H	-	-	-	NAD synthase
HPFPGLDM_02326	2.58e-168	-	-	-	Q	ko:K02066	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Permease MlaE
HPFPGLDM_02327	1.5e-190	-	-	-	Q	ko:K02065	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
HPFPGLDM_02328	1.82e-229	-	-	-	Q	ko:K02067	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	MlaD protein
HPFPGLDM_02329	2.69e-38	-	-	-	T	-	-	-	ribosome binding
HPFPGLDM_02332	5.1e-265	-	-	-	NU	ko:K02669	-	ko00000,ko02035,ko02044	Type II/IV secretion system protein
HPFPGLDM_02333	9.11e-261	-	-	-	NU	ko:K02669	-	ko00000,ko02035,ko02044	Type II/IV secretion system protein
HPFPGLDM_02334	1.66e-248	ppiD	5.2.1.8	-	O	ko:K03769,ko:K03770,ko:K03771,ko:K07533	-	ko00000,ko01000,ko03110	peptidyl-prolyl cis-trans isomerase activity
HPFPGLDM_02336	0.0	-	-	-	-	-	-	-	-
HPFPGLDM_02337	2.4e-180	kdsB	2.7.7.38	-	M	ko:K00979	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
HPFPGLDM_02338	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HPFPGLDM_02339	0.0	-	-	-	E	-	-	-	Sodium:solute symporter family
HPFPGLDM_02342	2.08e-08	-	-	-	-	-	-	-	-
HPFPGLDM_02352	6.16e-50	-	-	-	S	-	-	-	Caspase domain
HPFPGLDM_02355	2.32e-59	-	-	-	OU	-	-	-	Serine dehydrogenase proteinase
HPFPGLDM_02358	2.64e-267	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HPFPGLDM_02359	1.52e-268	-	-	-	E	-	-	-	FAD dependent oxidoreductase
HPFPGLDM_02360	4.93e-210	-	-	-	S	-	-	-	Rhomboid family
HPFPGLDM_02361	0.0	-	-	-	O	ko:K07391	-	ko00000	Magnesium chelatase, subunit ChlI C-terminal
HPFPGLDM_02362	2.68e-05	-	-	-	-	-	-	-	-
HPFPGLDM_02363	0.0	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Cys/Met metabolism PLP-dependent enzyme
HPFPGLDM_02364	1.32e-313	pqqE	-	-	C	ko:K06139	-	ko00000	SMART Elongator protein 3 MiaB NifB
HPFPGLDM_02365	1.99e-263	pqqE	-	-	C	ko:K06139	-	ko00000	SMART Elongator protein 3 MiaB NifB
HPFPGLDM_02367	8.62e-102	-	-	-	-	-	-	-	-
HPFPGLDM_02368	8.08e-236	gpsA	1.1.1.94	-	C	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
HPFPGLDM_02369	4.34e-152	-	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Glycerol-3-phosphate acyltransferase
HPFPGLDM_02370	1.02e-187	pppL	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	protein serine/threonine phosphatase activity
HPFPGLDM_02371	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class II (D, K and N)
HPFPGLDM_02372	0.0	-	1.2.7.1	-	C	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HPFPGLDM_02373	1.32e-101	manC	-	-	S	-	-	-	Cupin domain
HPFPGLDM_02374	3.2e-70	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HPFPGLDM_02375	0.0	-	-	-	G	-	-	-	Domain of unknown function (DUF4091)
HPFPGLDM_02376	2.58e-178	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HPFPGLDM_02378	4.33e-17	-	-	-	K	-	-	-	Helix-turn-helix domain
HPFPGLDM_02379	1.88e-207	-	-	-	S	-	-	-	Protein of unknown function (DUF1524)
HPFPGLDM_02380	0.0	-	-	-	P	-	-	-	Cation transport protein
HPFPGLDM_02381	3.52e-161	-	-	-	P	ko:K03499	-	ko00000,ko02000	TrkA-N domain
HPFPGLDM_02382	0.0	-	3.6.4.13	-	L	ko:K03578	-	ko00000,ko01000	Oligonucleotide/oligosaccharide-binding (OB)-fold
HPFPGLDM_02383	1.18e-109	-	2.2.1.6	-	E	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	ACT domain
HPFPGLDM_02384	0.0	-	-	-	O	-	-	-	Trypsin
HPFPGLDM_02385	4.27e-273	-	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III, delta subunit
HPFPGLDM_02386	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HPFPGLDM_02387	1.46e-262	-	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	RibD C-terminal domain
HPFPGLDM_02388	5.7e-157	-	-	-	M	-	-	-	Bacterial transferase hexapeptide (six repeats)
HPFPGLDM_02390	1.02e-258	-	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HPFPGLDM_02392	1.05e-252	-	3.3.1.1	-	H	ko:K01251	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	adenosylhomocysteinase activity
HPFPGLDM_02393	0.0	-	-	-	V	-	-	-	MatE
HPFPGLDM_02394	7.19e-179	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
HPFPGLDM_02395	2.63e-84	-	-	-	M	-	-	-	Lysin motif
HPFPGLDM_02396	1.78e-202	-	-	-	L	ko:K03424	-	ko00000,ko01000	TatD related DNase
HPFPGLDM_02397	2.08e-265	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2219)
HPFPGLDM_02398	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Beta galactosidase small chain
HPFPGLDM_02399	4.92e-06	-	-	-	-	-	-	-	-
HPFPGLDM_02401	0.0	-	2.7.13.3	-	T	ko:K07646	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Osmosensitive K+ channel His kinase sensor domain
HPFPGLDM_02402	9.8e-167	-	-	-	T	ko:K07667	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
HPFPGLDM_02404	0.0	-	3.6.3.12	-	P	ko:K01546	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
HPFPGLDM_02405	0.0	-	3.6.3.12	-	P	ko:K01547	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
HPFPGLDM_02406	2.36e-131	-	3.6.3.12	-	P	ko:K01548	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
HPFPGLDM_02407	1.76e-79	-	-	-	S	-	-	-	PFAM Cupin 2 conserved barrel domain protein
HPFPGLDM_02408	8.68e-229	-	-	-	K	-	-	-	DNA-binding transcription factor activity
HPFPGLDM_02409	0.0	-	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	C-terminal, D2-small domain, of ClpB protein