ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
MEFDBDGO_00001 4.83e-209 cps3D - - - - - - -
MEFDBDGO_00002 1.45e-145 cps3E - - - - - - -
MEFDBDGO_00003 1.41e-206 cps3F - - - - - - -
MEFDBDGO_00004 5.72e-262 cps3H - - - - - - -
MEFDBDGO_00005 2.31e-256 cps3I - - G - - - Acyltransferase family
MEFDBDGO_00006 4.87e-189 cps3J - - M - - - Domain of unknown function (DUF4422)
MEFDBDGO_00007 6.86e-175 - - - K - - - helix_turn_helix, arabinose operon control protein
MEFDBDGO_00008 0.0 - - - M - - - domain protein
MEFDBDGO_00009 5.36e-97 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
MEFDBDGO_00010 0.0 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
MEFDBDGO_00011 1.38e-155 rfbP - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 Bacterial sugar transferase
MEFDBDGO_00012 9.02e-70 - - - - - - - -
MEFDBDGO_00013 1.04e-45 - - - S - - - Protein of unknown function (DUF2922)
MEFDBDGO_00014 1.95e-41 - - - - - - - -
MEFDBDGO_00015 1.35e-34 - - - - - - - -
MEFDBDGO_00016 6.87e-131 - - - K - - - DNA-templated transcription, initiation
MEFDBDGO_00017 1.9e-168 - - - - - - - -
MEFDBDGO_00018 1.01e-181 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
MEFDBDGO_00019 6.62e-138 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
MEFDBDGO_00020 4.09e-172 lytE - - M - - - NlpC/P60 family
MEFDBDGO_00021 8.01e-64 - - - K - - - sequence-specific DNA binding
MEFDBDGO_00022 7.17e-39 - - - S - - - Antitoxin component of a toxin-antitoxin (TA) module
MEFDBDGO_00023 7.3e-216 hdhL 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
MEFDBDGO_00024 1.13e-257 yueF - - S - - - AI-2E family transporter
MEFDBDGO_00025 2.46e-93 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Glycerol-3-phosphate cytidylyltransferase
MEFDBDGO_00026 7.89e-290 gntP - - EG ko:K03299 - ko00000,ko02000 Gluconate
MEFDBDGO_00027 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
MEFDBDGO_00028 3.36e-216 gntZ 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
MEFDBDGO_00029 0.0 gshR3 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
MEFDBDGO_00030 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MEFDBDGO_00031 0.0 - - - - - - - -
MEFDBDGO_00032 1.49e-252 - - - M - - - MucBP domain
MEFDBDGO_00033 1.36e-208 lysR5 - - K - - - LysR substrate binding domain
MEFDBDGO_00034 1.01e-172 - - - S ko:K07090 - ko00000 membrane transporter protein
MEFDBDGO_00035 3.85e-76 ywjH - - S - - - Protein of unknown function (DUF1634)
MEFDBDGO_00036 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MEFDBDGO_00037 3.44e-210 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MEFDBDGO_00038 3.59e-241 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MEFDBDGO_00039 4.86e-258 oppD - - P ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MEFDBDGO_00040 5.67e-231 oppF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MEFDBDGO_00041 3.4e-85 - - - K - - - Winged helix DNA-binding domain
MEFDBDGO_00042 2.5e-132 - - - L - - - Integrase
MEFDBDGO_00043 0.0 clpE - - O ko:K03697 - ko00000,ko03110 Belongs to the ClpA ClpB family
MEFDBDGO_00044 5.6e-41 - - - - - - - -
MEFDBDGO_00045 1.24e-52 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
MEFDBDGO_00046 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MEFDBDGO_00047 1.41e-285 pimB 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
MEFDBDGO_00048 2.04e-254 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
MEFDBDGO_00049 2.16e-241 mprF - - I ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MEFDBDGO_00050 1.88e-291 dacA2 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
MEFDBDGO_00051 3.5e-292 araT - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
MEFDBDGO_00052 1.56e-46 ykuJ - - S - - - Protein of unknown function (DUF1797)
MEFDBDGO_00053 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MEFDBDGO_00056 1.35e-55 - - - S - - - COG NOG38524 non supervised orthologous group
MEFDBDGO_00068 3.26e-119 - 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Phosphoribosyl transferase domain
MEFDBDGO_00069 5.46e-238 - - - P ko:K06901 - ko00000,ko02000 secondary active sulfate transmembrane transporter activity
MEFDBDGO_00070 1.25e-124 - - - - - - - -
MEFDBDGO_00071 1.58e-122 - - - K - - - Acetyltransferase (GNAT) domain
MEFDBDGO_00072 2.07e-200 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
MEFDBDGO_00074 1.33e-292 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
MEFDBDGO_00075 2.53e-240 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
MEFDBDGO_00076 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
MEFDBDGO_00077 5.55e-216 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine S-methyltransferase
MEFDBDGO_00078 0.0 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
MEFDBDGO_00079 3.35e-157 - - - - - - - -
MEFDBDGO_00080 2.78e-273 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MEFDBDGO_00081 0.0 mdr - - EGP - - - Major Facilitator
MEFDBDGO_00082 6.25e-314 - - - N - - - Cell shape-determining protein MreB
MEFDBDGO_00083 0.0 - - - S - - - Pfam Methyltransferase
MEFDBDGO_00084 0.0 tagE2 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
MEFDBDGO_00085 0.0 tagE3 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
MEFDBDGO_00086 9.32e-40 - - - - - - - -
MEFDBDGO_00087 5.13e-138 mraW1 - - J - - - Putative rRNA methylase
MEFDBDGO_00088 1.78e-161 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
MEFDBDGO_00089 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
MEFDBDGO_00090 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
MEFDBDGO_00091 5.04e-176 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
MEFDBDGO_00092 9.06e-195 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MEFDBDGO_00093 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
MEFDBDGO_00094 2.16e-109 - - - T - - - Belongs to the universal stress protein A family
MEFDBDGO_00095 2.4e-257 ugpC 3.6.3.20 - E ko:K05816,ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the ABC transporter superfamily
MEFDBDGO_00096 4.59e-221 ugpA - - U ko:K02025,ko:K05814 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MEFDBDGO_00097 3.05e-193 ugpE - - G ko:K05815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MEFDBDGO_00098 0.0 ugpB - - G ko:K05813 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
MEFDBDGO_00099 7.52e-26 glpQ1 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
MEFDBDGO_00100 2.73e-122 glpQ1 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
MEFDBDGO_00101 2.07e-155 dgk2 - - F - - - deoxynucleoside kinase
MEFDBDGO_00102 3.55e-72 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MEFDBDGO_00103 7.61e-316 XK27_06930 - - V ko:K01421 - ko00000 domain protein
MEFDBDGO_00105 1.16e-160 - - - V ko:K01992 - ko00000,ko00002,ko02000 Transport permease protein
MEFDBDGO_00106 3.06e-201 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
MEFDBDGO_00107 2.57e-226 - - - K ko:K01990 - ko00000,ko00002,ko02000 LytTr DNA-binding domain
MEFDBDGO_00108 6.96e-198 mrsA1 1.8.4.11 - O ko:K07304 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MEFDBDGO_00109 5.2e-85 - - - K - - - helix_turn_helix, mercury resistance
MEFDBDGO_00110 4.69e-151 - - - GM - - - NAD(P)H-binding
MEFDBDGO_00111 6.31e-203 ydeD - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MEFDBDGO_00112 1.97e-191 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
MEFDBDGO_00113 7.83e-140 - - - - - - - -
MEFDBDGO_00114 1.25e-284 pltK 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
MEFDBDGO_00115 9.01e-179 agrA - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
MEFDBDGO_00116 5.37e-74 - - - - - - - -
MEFDBDGO_00117 4.56e-78 - - - - - - - -
MEFDBDGO_00118 4.31e-146 XK27_07085 - - S ko:K07052 - ko00000 CAAX protease self-immunity
MEFDBDGO_00119 2.19e-52 ohrR - - K ko:K18906 - ko00000,ko00002,ko01504,ko03000 helix_turn_helix multiple antibiotic resistance protein
MEFDBDGO_00120 8.82e-119 - - - - - - - -
MEFDBDGO_00121 7.12e-62 - - - - - - - -
MEFDBDGO_00122 0.0 uvrA2 - - L - - - ABC transporter
MEFDBDGO_00124 2.11e-273 - - - S - - - Phage integrase family
MEFDBDGO_00131 4.07e-34 - - - CE - - - IrrE N-terminal-like domain
MEFDBDGO_00132 7.45e-17 - - - K - - - Cro/C1-type HTH DNA-binding domain
MEFDBDGO_00134 2.35e-129 - - - K - - - ORF6N domain
MEFDBDGO_00135 9.15e-77 - - - S - - - ORF6C domain
MEFDBDGO_00136 2.69e-77 - - - S - - - Domain of unknown function (DUF771)
MEFDBDGO_00139 2.46e-20 - - - - - - - -
MEFDBDGO_00142 2.61e-170 - - - S - - - Putative HNHc nuclease
MEFDBDGO_00143 1.33e-94 - - - L - - - DnaD domain protein
MEFDBDGO_00144 6.69e-168 - - - L ko:K02315 - ko00000,ko03032 IstB-like ATP binding protein
MEFDBDGO_00146 9.52e-76 - - - - - - - -
MEFDBDGO_00147 1.29e-83 - - - L - - - Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
MEFDBDGO_00148 5.02e-21 - - - - - - - -
MEFDBDGO_00150 2.81e-29 - - - S - - - YopX protein
MEFDBDGO_00152 3.09e-96 - - - S - - - Transcriptional regulator, RinA family
MEFDBDGO_00156 1.41e-115 - - - L - - - HNH nucleases
MEFDBDGO_00157 5.28e-100 - - - L - - - Phage terminase, small subunit
MEFDBDGO_00158 0.0 - - - S - - - Phage Terminase
MEFDBDGO_00159 1.64e-35 - - - S - - - Protein of unknown function (DUF1056)
MEFDBDGO_00160 1.47e-285 - - - S - - - Phage portal protein
MEFDBDGO_00161 1.53e-159 - - - S - - - Clp protease
MEFDBDGO_00162 6.63e-263 - - - S - - - peptidase activity
MEFDBDGO_00163 2.9e-68 - - - S - - - Phage gp6-like head-tail connector protein
MEFDBDGO_00164 1.11e-72 - - - S - - - Phage head-tail joining protein
MEFDBDGO_00165 2.44e-90 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
MEFDBDGO_00166 6.4e-75 - - - S - - - Protein of unknown function (DUF806)
MEFDBDGO_00167 9.19e-135 - - - S - - - Phage tail tube protein
MEFDBDGO_00168 1.16e-76 - - - S - - - Phage tail assembly chaperone proteins, TAC
MEFDBDGO_00169 7.28e-27 - - - - - - - -
MEFDBDGO_00170 0.0 - - - D - - - domain protein
MEFDBDGO_00171 7.85e-260 - - - S - - - Phage tail protein
MEFDBDGO_00172 0.0 - - - S - - - Phage minor structural protein
MEFDBDGO_00176 1.33e-62 - - - - - - - -
MEFDBDGO_00177 6.9e-47 - - - LM - - - DNA recombination
MEFDBDGO_00178 6.4e-258 - - - M - - - Glycosyl hydrolases family 25
MEFDBDGO_00179 2.16e-48 - - - S - - - Haemolysin XhlA
MEFDBDGO_00182 6.09e-87 - - - - - - - -
MEFDBDGO_00183 9.03e-16 - - - - - - - -
MEFDBDGO_00184 3.89e-237 - - - - - - - -
MEFDBDGO_00185 4.91e-117 gtcA1 - - S - - - Teichoic acid glycosylation protein
MEFDBDGO_00186 8.01e-77 - - - S - - - Protein of unknown function (DUF1516)
MEFDBDGO_00187 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
MEFDBDGO_00188 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MEFDBDGO_00189 0.0 - - - S - - - Protein conserved in bacteria
MEFDBDGO_00190 5.16e-292 sat 2.7.7.4 - H ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms
MEFDBDGO_00191 3.72e-145 cysC 2.7.1.25 - F ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
MEFDBDGO_00192 1.08e-226 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain
MEFDBDGO_00193 0.0 astA 2.8.2.22 - M ko:K01023 - ko00000,ko01000 Arylsulfotransferase Ig-like domain
MEFDBDGO_00194 0.0 - - - P - - - Sodium:sulfate symporter transmembrane region
MEFDBDGO_00195 2.69e-316 dinF - - V - - - MatE
MEFDBDGO_00196 1.79e-42 - - - - - - - -
MEFDBDGO_00199 7.02e-103 yybD - - S ko:K02348 - ko00000 Acetyltransferase (GNAT) domain
MEFDBDGO_00200 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
MEFDBDGO_00201 1.97e-107 - - - - - - - -
MEFDBDGO_00202 0.0 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
MEFDBDGO_00203 6.25e-138 - - - - - - - -
MEFDBDGO_00204 5.63e-192 - - - EGP ko:K08218 ko01501,map01501 ko00000,ko00001,ko00002,ko02000 Major facilitator Superfamily
MEFDBDGO_00205 1.55e-70 - - - EGP ko:K08218 ko01501,map01501 ko00000,ko00001,ko00002,ko02000 Major facilitator Superfamily
MEFDBDGO_00206 1.72e-148 yciB - - M - - - ErfK YbiS YcfS YnhG
MEFDBDGO_00207 1.65e-46 dltC2 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MEFDBDGO_00208 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 Alanine-glyoxylate amino-transferase
MEFDBDGO_00209 3.29e-132 argO - - S ko:K06895 - ko00000,ko02000 LysE type translocator
MEFDBDGO_00210 5.58e-271 arcT - - E - - - Aminotransferase
MEFDBDGO_00211 2.07e-102 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
MEFDBDGO_00212 2.43e-18 - - - - - - - -
MEFDBDGO_00213 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
MEFDBDGO_00214 9.94e-71 yheA - - S - - - Belongs to the UPF0342 family
MEFDBDGO_00215 1.49e-294 yhaO - - L ko:K03547 - ko00000,ko03400 Ser Thr phosphatase family protein
MEFDBDGO_00216 0.0 yhaN - - L - - - AAA domain
MEFDBDGO_00217 2.08e-240 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 Metal dependent phosphohydrolases with conserved 'HD' motif.
MEFDBDGO_00218 5.69e-277 - - - - - - - -
MEFDBDGO_00219 3.16e-116 - - - M - - - Peptidase family S41
MEFDBDGO_00220 1.06e-72 - - - M - - - Peptidase family S41
MEFDBDGO_00221 6.59e-227 - - - K - - - LysR substrate binding domain
MEFDBDGO_00222 9.9e-144 - - - S - - - NADPH-dependent FMN reductase
MEFDBDGO_00223 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
MEFDBDGO_00224 4.43e-129 - - - - - - - -
MEFDBDGO_00225 1.17e-100 - 2.4.2.6 - F ko:K08728 ko00240,map00240 ko00000,ko00001,ko01000 Nucleoside 2-deoxyribosyltransferase
MEFDBDGO_00226 1.78e-72 - - - M - - - domain protein
MEFDBDGO_00227 3.66e-167 - - - M - - - domain protein
MEFDBDGO_00228 7.13e-59 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
MEFDBDGO_00229 6.28e-69 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
MEFDBDGO_00230 1.81e-64 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
MEFDBDGO_00231 0.0 - - - P - - - Cation transporter/ATPase, N-terminus
MEFDBDGO_00232 4.09e-253 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MEFDBDGO_00233 0.0 - - - L - - - ATPase domain of DNA mismatch repair MUTS family
MEFDBDGO_00234 0.0 - - - L - - - MutS domain V
MEFDBDGO_00235 1.57e-233 ykoT - - M - - - Glycosyl transferase family 2
MEFDBDGO_00236 0.0 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MEFDBDGO_00237 2.24e-87 - - - S - - - NUDIX domain
MEFDBDGO_00238 0.0 - - - S - - - membrane
MEFDBDGO_00239 4.26e-218 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MEFDBDGO_00240 8.71e-111 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
MEFDBDGO_00241 2.08e-284 ribA 3.5.4.25, 4.1.99.12 - H ko:K02858,ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
MEFDBDGO_00242 1.23e-106 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
MEFDBDGO_00243 5.21e-137 - - - S ko:K09962 - ko00000 Nucleotidyltransferase
MEFDBDGO_00244 3.39e-138 - - - - - - - -
MEFDBDGO_00245 2.71e-150 crp2 - - K ko:K10914,ko:K21562 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 helix_turn_helix, cAMP Regulatory protein
MEFDBDGO_00246 4.89e-146 - - - K - - - Bacterial regulatory proteins, tetR family
MEFDBDGO_00247 5.19e-309 npr 1.11.1.1 - C ko:K05910 - ko00000,ko01000 NADH oxidase
MEFDBDGO_00248 0.0 - - - - - - - -
MEFDBDGO_00249 4.75e-80 - - - - - - - -
MEFDBDGO_00250 3.36e-248 - - - S - - - Fn3-like domain
MEFDBDGO_00251 5.69e-138 - - - S - - - WxL domain surface cell wall-binding
MEFDBDGO_00252 5.76e-135 - - - S - - - WxL domain surface cell wall-binding
MEFDBDGO_00253 1.09e-196 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MEFDBDGO_00254 6.76e-73 - - - - - - - -
MEFDBDGO_00255 3.6e-106 hit - - FG ko:K02503 - ko00000,ko04147 histidine triad
MEFDBDGO_00256 1.1e-174 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MEFDBDGO_00257 9.53e-284 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
MEFDBDGO_00258 7.24e-197 ytmP - - M - - - Choline/ethanolamine kinase
MEFDBDGO_00259 4.7e-156 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MEFDBDGO_00260 2.94e-71 ytzB - - S - - - Peptidase propeptide and YPEB domain
MEFDBDGO_00261 1.45e-145 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MEFDBDGO_00262 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
MEFDBDGO_00263 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
MEFDBDGO_00264 3.04e-29 - - - S - - - Virus attachment protein p12 family
MEFDBDGO_00265 0.0 feoB - - P ko:K04759 - ko00000,ko02000 transporter of a GTP-driven Fe(2 ) uptake system
MEFDBDGO_00266 2.87e-47 feoA - - P ko:K04758 - ko00000,ko02000 FeoA domain
MEFDBDGO_00267 1.1e-184 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
MEFDBDGO_00268 5.21e-311 sufD - - O ko:K07033,ko:K09015 - ko00000 FeS assembly protein SufD
MEFDBDGO_00269 5.93e-298 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MEFDBDGO_00270 7.76e-108 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
MEFDBDGO_00271 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
MEFDBDGO_00272 4.07e-60 - - - S - - - Iron-sulfur cluster assembly protein
MEFDBDGO_00273 1.04e-141 - - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
MEFDBDGO_00274 8.51e-155 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
MEFDBDGO_00275 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MEFDBDGO_00276 1.52e-200 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MEFDBDGO_00277 1.85e-131 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MEFDBDGO_00278 1.58e-117 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MEFDBDGO_00279 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 replication initiation and membrane attachment
MEFDBDGO_00280 6.05e-221 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
MEFDBDGO_00281 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MEFDBDGO_00282 2.37e-109 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MEFDBDGO_00283 6.92e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
MEFDBDGO_00284 6.88e-73 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MEFDBDGO_00285 9.27e-73 - - - - - - - -
MEFDBDGO_00286 1.16e-305 - - - L ko:K07478 - ko00000 AAA C-terminal domain
MEFDBDGO_00287 8.28e-251 qor 1.1.1.1, 1.6.5.5 - C ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
MEFDBDGO_00288 1.64e-83 ydeP - - K - - - Transcriptional regulator, HxlR family
MEFDBDGO_00289 2.79e-174 racD 5.1.1.13 - G ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
MEFDBDGO_00290 0.0 yijG - GT2 M ko:K11936 ko02026,map02026 ko00000,ko00001,ko01000,ko01003,ko02000 Glycosyl transferase
MEFDBDGO_00291 6.32e-114 - - - - - - - -
MEFDBDGO_00292 5.7e-127 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
MEFDBDGO_00293 1.33e-276 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
MEFDBDGO_00294 2.19e-67 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein
MEFDBDGO_00295 4.19e-153 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MEFDBDGO_00296 9.92e-149 yqeK - - H - - - Hydrolase, HD family
MEFDBDGO_00297 1.06e-76 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MEFDBDGO_00298 3.3e-180 yqeM - - Q - - - Methyltransferase
MEFDBDGO_00299 2.05e-278 ylbM - - S - - - Belongs to the UPF0348 family
MEFDBDGO_00300 3.66e-127 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
MEFDBDGO_00301 3.06e-124 - - - S - - - Peptidase propeptide and YPEB domain
MEFDBDGO_00302 6.29e-223 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MEFDBDGO_00303 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MEFDBDGO_00304 7.66e-312 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
MEFDBDGO_00305 1.38e-155 csrR - - K - - - response regulator
MEFDBDGO_00306 0.0 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MEFDBDGO_00307 1.93e-218 ubiA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
MEFDBDGO_00308 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 Putative exonuclease SbcCD, C subunit
MEFDBDGO_00309 5.55e-288 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
MEFDBDGO_00310 1.77e-122 - - - S - - - SdpI/YhfL protein family
MEFDBDGO_00311 1.4e-208 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MEFDBDGO_00312 2.36e-60 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
MEFDBDGO_00313 6.34e-179 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MEFDBDGO_00314 1.72e-120 XK27_09705 - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
MEFDBDGO_00315 1.09e-83 yodB - - K - - - Transcriptional regulator, HxlR family
MEFDBDGO_00316 6.88e-257 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MEFDBDGO_00317 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MEFDBDGO_00318 6.11e-249 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MEFDBDGO_00319 7.5e-146 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
MEFDBDGO_00320 1.09e-105 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MEFDBDGO_00321 7.98e-145 - - - S - - - membrane
MEFDBDGO_00322 5.72e-99 - - - K - - - LytTr DNA-binding domain
MEFDBDGO_00323 6.12e-72 yneR - - S - - - Belongs to the HesB IscA family
MEFDBDGO_00324 0.0 - - - S - - - membrane
MEFDBDGO_00325 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
MEFDBDGO_00326 5.33e-30 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
MEFDBDGO_00327 5.38e-131 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MEFDBDGO_00328 3.52e-153 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Peptidase, S54 family
MEFDBDGO_00329 6.33e-46 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
MEFDBDGO_00330 6.12e-230 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
MEFDBDGO_00331 1.28e-138 pepE 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
MEFDBDGO_00332 1.15e-89 yqhL - - P - - - Rhodanese-like protein
MEFDBDGO_00333 1.44e-31 WQ51_02665 - - S - - - Protein of unknown function (DUF3042)
MEFDBDGO_00334 2.23e-178 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 phosphodiesterase
MEFDBDGO_00335 3.12e-223 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MEFDBDGO_00336 7.79e-85 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 Transcriptional regulator
MEFDBDGO_00337 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
MEFDBDGO_00338 1.77e-205 - - - - - - - -
MEFDBDGO_00339 1.34e-232 - - - - - - - -
MEFDBDGO_00340 3.55e-127 - - - S - - - Protein conserved in bacteria
MEFDBDGO_00341 5.37e-74 - - - - - - - -
MEFDBDGO_00342 2.97e-41 - - - - - - - -
MEFDBDGO_00345 9.81e-27 - - - - - - - -
MEFDBDGO_00346 8.15e-125 - - - K - - - Transcriptional regulator
MEFDBDGO_00347 1.55e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
MEFDBDGO_00348 7.97e-71 ysxB - - J ko:K07584 - ko00000 Cysteine protease Prp
MEFDBDGO_00349 2.33e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
MEFDBDGO_00350 3.49e-248 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
MEFDBDGO_00351 1.43e-129 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MEFDBDGO_00352 1.7e-96 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
MEFDBDGO_00353 2.82e-91 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MEFDBDGO_00354 4.82e-194 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MEFDBDGO_00355 2.81e-313 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MEFDBDGO_00356 7.55e-44 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MEFDBDGO_00357 6.68e-206 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
MEFDBDGO_00358 4.49e-192 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
MEFDBDGO_00359 5.28e-100 argR2 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
MEFDBDGO_00360 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
MEFDBDGO_00361 4.51e-284 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MEFDBDGO_00362 7.11e-135 opuCB - - E ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MEFDBDGO_00363 3.8e-224 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MEFDBDGO_00364 1.36e-136 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MEFDBDGO_00365 8.28e-73 - - - - - - - -
MEFDBDGO_00366 6.96e-145 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
MEFDBDGO_00367 3.93e-41 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MEFDBDGO_00368 5.04e-278 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MEFDBDGO_00369 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MEFDBDGO_00370 5.2e-225 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MEFDBDGO_00371 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MEFDBDGO_00372 1.62e-173 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
MEFDBDGO_00373 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
MEFDBDGO_00374 9.9e-209 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MEFDBDGO_00375 3.16e-151 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
MEFDBDGO_00376 1.24e-158 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
MEFDBDGO_00377 1.61e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
MEFDBDGO_00378 7.09e-76 yloU - - S - - - Asp23 family, cell envelope-related function
MEFDBDGO_00379 0.0 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
MEFDBDGO_00380 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MEFDBDGO_00381 2.17e-244 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MEFDBDGO_00382 3.33e-47 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
MEFDBDGO_00383 4.49e-167 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MEFDBDGO_00384 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
MEFDBDGO_00385 2.85e-293 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MEFDBDGO_00386 1.46e-77 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MEFDBDGO_00387 7.69e-300 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MEFDBDGO_00388 1.6e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
MEFDBDGO_00389 9.99e-53 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
MEFDBDGO_00390 2.24e-123 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MEFDBDGO_00391 1.57e-179 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
MEFDBDGO_00392 3.15e-78 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MEFDBDGO_00393 6.21e-68 - - - - - - - -
MEFDBDGO_00394 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
MEFDBDGO_00395 1.1e-112 - - - - - - - -
MEFDBDGO_00396 2.05e-179 ecsA_2 - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
MEFDBDGO_00397 0.0 XK27_00765 - - - ko:K01992 - ko00000,ko00002,ko02000 -
MEFDBDGO_00398 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Anthranilate synthase component I, N terminal region
MEFDBDGO_00399 8.08e-135 trpG 4.1.3.27 - EH ko:K01658 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Peptidase C26
MEFDBDGO_00400 1.42e-224 trpD 2.4.2.18, 4.1.3.27 - F ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MEFDBDGO_00401 6.06e-159 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
MEFDBDGO_00402 1.51e-140 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
MEFDBDGO_00403 1.79e-287 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MEFDBDGO_00404 4.82e-183 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
MEFDBDGO_00405 1.45e-126 entB - - Q - - - Isochorismatase family
MEFDBDGO_00406 3.53e-227 - 1.6.5.5 - C ko:K00344 - ko00000,ko01000 Zinc-binding dehydrogenase
MEFDBDGO_00407 1.6e-87 ybbJ - - K - - - Acetyltransferase (GNAT) family
MEFDBDGO_00408 1.62e-276 - - - E - - - glutamate:sodium symporter activity
MEFDBDGO_00409 1.38e-273 hipO1 - - E ko:K21613 - ko00000,ko01000,ko01002 Peptidase family M20/M25/M40
MEFDBDGO_00410 1.56e-251 adhB 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
MEFDBDGO_00411 2.12e-77 - - - S - - - Protein of unknown function (DUF1648)
MEFDBDGO_00412 6.84e-186 yneD - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
MEFDBDGO_00413 8.02e-230 yneE - - K - - - Transcriptional regulator
MEFDBDGO_00414 8.55e-99 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MEFDBDGO_00415 1.97e-230 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MEFDBDGO_00416 6.16e-48 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
MEFDBDGO_00417 2.97e-216 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
MEFDBDGO_00418 1.26e-162 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
MEFDBDGO_00419 5.38e-290 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MEFDBDGO_00420 5.25e-96 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MEFDBDGO_00421 7.23e-93 fabZ2 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
MEFDBDGO_00422 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
MEFDBDGO_00423 2.62e-202 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MEFDBDGO_00424 8e-178 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 alpha subunit
MEFDBDGO_00425 5.4e-174 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
MEFDBDGO_00426 1.01e-128 - - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
MEFDBDGO_00427 3.64e-162 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
MEFDBDGO_00428 1.07e-206 - - - K - - - LysR substrate binding domain
MEFDBDGO_00429 4.94e-114 ykhA - - I - - - Thioesterase superfamily
MEFDBDGO_00430 2.66e-247 rsgA_2 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MEFDBDGO_00431 2.46e-120 - - - K - - - transcriptional regulator
MEFDBDGO_00432 0.0 - - - EGP - - - Major Facilitator
MEFDBDGO_00433 6.56e-193 - - - O - - - Band 7 protein
MEFDBDGO_00434 8.39e-100 - - - L - - - Pfam:Integrase_AP2
MEFDBDGO_00435 2.56e-160 - 2.1.1.37 - L ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 C-5 cytosine-specific DNA methylase
MEFDBDGO_00436 1.99e-193 - - - L - - - This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MEFDBDGO_00440 1.01e-31 - - - - - - - -
MEFDBDGO_00443 1.98e-49 - - - S - - - protein disulfide oxidoreductase activity
MEFDBDGO_00446 1.23e-25 - - - K - - - Cro/C1-type HTH DNA-binding domain
MEFDBDGO_00447 2.1e-16 - - - K - - - Cro/C1-type HTH DNA-binding domain
MEFDBDGO_00448 1.65e-07 - - - K ko:K07729 - ko00000,ko03000 sequence-specific DNA binding
MEFDBDGO_00456 4.68e-46 - - - - - - - -
MEFDBDGO_00457 1.12e-121 - - - S - - - AAA domain
MEFDBDGO_00458 6.02e-69 - - - S - - - Protein of unknown function (DUF669)
MEFDBDGO_00459 2.75e-41 - - - L - - - DnaD domain protein
MEFDBDGO_00460 4.18e-201 - - - S - - - IstB-like ATP binding protein
MEFDBDGO_00462 5.85e-57 - - - - - - - -
MEFDBDGO_00463 0.0 - - - S - - - Psort location CytoplasmicMembrane, score
MEFDBDGO_00464 5.95e-74 - - - S - - - Transcriptional regulator, RinA family
MEFDBDGO_00465 1.09e-42 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
MEFDBDGO_00466 1.4e-46 - - - - - - - -
MEFDBDGO_00469 3.55e-42 - - - S - - - Helix-turn-helix of insertion element transposase
MEFDBDGO_00470 0.0 - - - S ko:K06909 - ko00000 Phage terminase, large subunit
MEFDBDGO_00471 0.0 - - - S - - - Phage portal protein, SPP1 Gp6-like
MEFDBDGO_00472 2.38e-224 - - - S - - - Phage Mu protein F like protein
MEFDBDGO_00473 4.61e-111 - - - S - - - Domain of unknown function (DUF4355)
MEFDBDGO_00474 9.95e-245 gpG - - - - - - -
MEFDBDGO_00475 2.36e-70 - - - S - - - Phage gp6-like head-tail connector protein
MEFDBDGO_00476 8.45e-62 - - - - - - - -
MEFDBDGO_00477 3.47e-116 - - - - - - - -
MEFDBDGO_00478 1.9e-86 - - - - - - - -
MEFDBDGO_00479 5.14e-137 - - - - - - - -
MEFDBDGO_00480 1.41e-115 - - - S - - - Phage tail assembly chaperone protein, TAC
MEFDBDGO_00482 0.0 - - - D - - - domain protein
MEFDBDGO_00483 1.19e-182 - - - S - - - phage tail
MEFDBDGO_00484 0.0 - - - M - - - Prophage endopeptidase tail
MEFDBDGO_00485 2.84e-240 - - - E - - - GDSL-like Lipase/Acylhydrolase family
MEFDBDGO_00486 1.92e-141 - - - S - - - Domain of unknown function (DUF2479)
MEFDBDGO_00489 2.56e-34 - - - S - - - Phage uncharacterised protein (Phage_XkdX)
MEFDBDGO_00490 5.58e-189 - - - M - - - hydrolase, family 25
MEFDBDGO_00491 4.01e-35 - - - S - - - Haemolysin XhlA
MEFDBDGO_00492 1.05e-22 - - - S - - - Bacteriophage holin
MEFDBDGO_00493 2.74e-05 - - - - - - - -
MEFDBDGO_00495 1.19e-129 - 1.14.99.53 AA10 S ko:K21713 - ko00000,ko01000 Lytic polysaccharide mono-oxygenase, cellulose-degrading
MEFDBDGO_00497 3.94e-30 - - - L - - - Pfam:Integrase_AP2
MEFDBDGO_00500 1.19e-13 - - - - - - - -
MEFDBDGO_00502 1.43e-69 - - - - - - - -
MEFDBDGO_00503 1.42e-39 - - - - - - - -
MEFDBDGO_00504 1.69e-276 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
MEFDBDGO_00505 9.96e-147 - 1.14.99.53 AA10 S ko:K21713 - ko00000,ko01000 Lytic polysaccharide mono-oxygenase, cellulose-degrading
MEFDBDGO_00506 3.16e-64 ycnE - - S - - - Antibiotic biosynthesis monooxygenase
MEFDBDGO_00507 2.05e-55 - - - - - - - -
MEFDBDGO_00508 4.98e-107 tspO - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 TspO/MBR family
MEFDBDGO_00509 3.05e-99 - - - T - - - Belongs to the universal stress protein A family
MEFDBDGO_00510 3.92e-87 - - - S - - - Protein of unknown function (DUF805)
MEFDBDGO_00511 1.79e-211 - - - I - - - Diacylglycerol kinase catalytic domain
MEFDBDGO_00512 1.51e-48 - - - - - - - -
MEFDBDGO_00513 5.79e-21 - - - - - - - -
MEFDBDGO_00514 2.22e-55 - - - S - - - transglycosylase associated protein
MEFDBDGO_00515 4e-40 - - - S - - - CsbD-like
MEFDBDGO_00516 1.06e-53 - - - - - - - -
MEFDBDGO_00517 0.0 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
MEFDBDGO_00518 4.87e-37 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
MEFDBDGO_00519 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MEFDBDGO_00520 1.04e-218 - 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 UbiA prenyltransferase family
MEFDBDGO_00521 5.03e-182 - - - U ko:K10716 - ko00000,ko02000 Ion channel
MEFDBDGO_00522 1.52e-67 - - - - - - - -
MEFDBDGO_00523 2.12e-57 - - - - - - - -
MEFDBDGO_00524 0.0 gabT 2.6.1.19, 5.1.1.21 - E ko:K00823,ko:K20708 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MEFDBDGO_00525 0.0 - - - E ko:K03294 - ko00000 Amino Acid
MEFDBDGO_00526 3.86e-192 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
MEFDBDGO_00527 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
MEFDBDGO_00528 2.06e-158 - - - S - - - Domain of unknown function (DUF4767)
MEFDBDGO_00529 0.0 malT - - G ko:K16211 - ko00000,ko02000 Major Facilitator
MEFDBDGO_00530 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
MEFDBDGO_00531 9.23e-245 galM2 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
MEFDBDGO_00532 1.01e-249 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MEFDBDGO_00533 1.77e-262 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
MEFDBDGO_00534 1.1e-230 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
MEFDBDGO_00535 1.48e-217 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 mevalonate kinase
MEFDBDGO_00536 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
MEFDBDGO_00537 2.53e-107 ypmB - - S - - - protein conserved in bacteria
MEFDBDGO_00538 3.1e-289 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
MEFDBDGO_00539 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
MEFDBDGO_00540 1.13e-165 dnaD - - L ko:K02086 - ko00000 Replication initiation and membrane attachment
MEFDBDGO_00542 2.32e-238 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MEFDBDGO_00543 2.45e-142 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MEFDBDGO_00544 1.3e-202 metQ1 - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
MEFDBDGO_00545 5.32e-109 - - - T - - - Universal stress protein family
MEFDBDGO_00546 0.0 ftpA - - P ko:K02011 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MEFDBDGO_00547 3.28e-233 ftpB - - P ko:K02012 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
MEFDBDGO_00548 2.7e-65 phnT 3.6.3.30 - P ko:K02010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
MEFDBDGO_00549 2.37e-142 phnT 3.6.3.30 - P ko:K02010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
MEFDBDGO_00550 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
MEFDBDGO_00551 3.6e-152 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MEFDBDGO_00552 2.12e-142 ypsA - - S - - - Belongs to the UPF0398 family
MEFDBDGO_00553 9.98e-75 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MEFDBDGO_00555 1.44e-282 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
MEFDBDGO_00557 1.7e-185 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
MEFDBDGO_00558 2.26e-95 - - - S - - - SnoaL-like domain
MEFDBDGO_00559 3.2e-254 - - - M - - - Glycosyltransferase, group 2 family protein
MEFDBDGO_00560 2.85e-266 mccF - - V - - - LD-carboxypeptidase
MEFDBDGO_00561 1.66e-101 - - - K - - - Acetyltransferase (GNAT) domain
MEFDBDGO_00562 2.13e-312 - - - M ko:K07273 - ko00000 hydrolase, family 25
MEFDBDGO_00563 1.44e-234 - - - V - - - LD-carboxypeptidase
MEFDBDGO_00564 1.99e-159 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
MEFDBDGO_00565 3.99e-158 - - - P ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
MEFDBDGO_00566 1.37e-248 - - - - - - - -
MEFDBDGO_00567 1.5e-186 - - - S - - - hydrolase activity, acting on ester bonds
MEFDBDGO_00568 1.47e-268 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 FAD dependent oxidoreductase
MEFDBDGO_00569 3.28e-87 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease HI
MEFDBDGO_00570 5.04e-82 esbA - - S - - - Family of unknown function (DUF5322)
MEFDBDGO_00571 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
MEFDBDGO_00572 1.65e-97 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MEFDBDGO_00573 9.72e-225 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
MEFDBDGO_00574 1.9e-115 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MEFDBDGO_00575 4.89e-263 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarA family
MEFDBDGO_00576 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
MEFDBDGO_00577 0.0 - - - S - - - Bacterial membrane protein, YfhO
MEFDBDGO_00578 2.01e-145 - - - G - - - Phosphoglycerate mutase family
MEFDBDGO_00579 1.9e-93 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
MEFDBDGO_00582 1.92e-168 cat 2.3.1.28 - V ko:K19271 - br01600,ko00000,ko01000,ko01504 Chloramphenicol acetyltransferase
MEFDBDGO_00583 2.08e-92 - - - S - - - LuxR family transcriptional regulator
MEFDBDGO_00584 1.19e-176 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2087)
MEFDBDGO_00585 1.87e-117 - - - F - - - NUDIX domain
MEFDBDGO_00586 1.03e-206 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MEFDBDGO_00587 9.28e-171 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
MEFDBDGO_00588 0.0 FbpA - - K - - - Fibronectin-binding protein
MEFDBDGO_00589 1.97e-87 - - - K - - - Transcriptional regulator
MEFDBDGO_00590 1.11e-205 - - - S - - - EDD domain protein, DegV family
MEFDBDGO_00591 2.47e-101 yjcF 3.5.4.33, 4.4.1.8 - K ko:K02348,ko:K11991,ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007,ko03016 protein acetylation
MEFDBDGO_00592 2.9e-170 - - - S - - - Protein of unknown function (DUF975)
MEFDBDGO_00593 9.43e-39 - - - - - - - -
MEFDBDGO_00594 5.59e-64 - - - - - - - -
MEFDBDGO_00595 6.64e-189 - - - C - - - Domain of unknown function (DUF4931)
MEFDBDGO_00596 3.87e-264 pmrB - - EGP - - - Major Facilitator Superfamily
MEFDBDGO_00598 1.33e-67 XK27_08430 - - S - - - Staphylococcal protein of unknown function (DUF960)
MEFDBDGO_00599 4.68e-73 yejC - - S - - - Protein of unknown function (DUF1003)
MEFDBDGO_00600 8.68e-74 yejC - - S - - - Protein of unknown function (DUF1003)
MEFDBDGO_00601 2.59e-177 XK27_00890 - - S ko:K08974 - ko00000 Domain of unknown function (DUF368)
MEFDBDGO_00602 4.31e-312 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
MEFDBDGO_00603 1.5e-253 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
MEFDBDGO_00604 0.0 qacA - - EGP - - - Major Facilitator
MEFDBDGO_00605 2.48e-252 XK27_00915 - - C - - - Luciferase-like monooxygenase
MEFDBDGO_00606 3.36e-155 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
MEFDBDGO_00607 1.22e-219 cpsY - - K - - - Transcriptional regulator, LysR family
MEFDBDGO_00608 5.13e-292 XK27_05470 - - E - - - Methionine synthase
MEFDBDGO_00610 1.85e-206 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MEFDBDGO_00611 2.04e-175 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MEFDBDGO_00612 8.11e-203 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
MEFDBDGO_00613 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MEFDBDGO_00614 0.0 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MEFDBDGO_00615 1.5e-227 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family. XerC subfamily
MEFDBDGO_00616 6.84e-121 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MEFDBDGO_00617 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MEFDBDGO_00618 1.27e-217 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
MEFDBDGO_00619 2.4e-137 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MEFDBDGO_00620 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MEFDBDGO_00621 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MEFDBDGO_00622 3.82e-228 - - - K - - - Transcriptional regulator
MEFDBDGO_00623 3.91e-216 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
MEFDBDGO_00624 3.8e-105 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
MEFDBDGO_00625 9.17e-126 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MEFDBDGO_00626 1.07e-43 - - - S - - - YozE SAM-like fold
MEFDBDGO_00627 3.44e-202 - - - L - - - Phage integrase, N-terminal SAM-like domain
MEFDBDGO_00628 0.0 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MEFDBDGO_00629 6.1e-313 - - - M - - - Glycosyl transferase family group 2
MEFDBDGO_00630 1.08e-79 - - - - - - - -
MEFDBDGO_00631 0.0 gshR1 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
MEFDBDGO_00632 1.48e-98 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
MEFDBDGO_00633 4.87e-123 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
MEFDBDGO_00634 0.0 tarL 2.7.8.14, 2.7.8.47 - H ko:K18704 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MEFDBDGO_00635 3.21e-247 tarK 2.7.8.14, 2.7.8.46, 2.7.8.47 - H ko:K18704,ko:K21592 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MEFDBDGO_00636 2.44e-242 tarJ 1.1.1.137, 1.1.1.405 - E ko:K05352,ko:K21680 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
MEFDBDGO_00637 7.15e-165 tarI 2.7.7.40, 2.7.7.60 - I ko:K00991,ko:K21030 ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
MEFDBDGO_00638 6.75e-290 - - - - - - - -
MEFDBDGO_00639 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
MEFDBDGO_00640 7.79e-78 - - - - - - - -
MEFDBDGO_00641 1.3e-174 - - - - - - - -
MEFDBDGO_00642 2.13e-253 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
MEFDBDGO_00643 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
MEFDBDGO_00644 9.33e-48 yozE - - S - - - Belongs to the UPF0346 family
MEFDBDGO_00645 3.29e-147 ypmS - - S - - - Uncharacterized protein conserved in bacteria (DUF2140)
MEFDBDGO_00646 2.4e-208 XK27_03630 - - E - - - GDSL-like Lipase/Acylhydrolase
MEFDBDGO_00647 2.88e-189 WQ51_01275 - - S - - - EDD domain protein, DegV family
MEFDBDGO_00648 1.8e-119 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MEFDBDGO_00649 6.7e-241 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MEFDBDGO_00650 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 ABC transporter, ATP-binding protein
MEFDBDGO_00651 6.46e-109 - - - - - - - -
MEFDBDGO_00652 8.95e-292 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MEFDBDGO_00653 1.39e-185 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MEFDBDGO_00654 3.71e-192 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
MEFDBDGO_00655 5.96e-284 XK27_05225 - - S - - - Tetratricopeptide repeat protein
MEFDBDGO_00656 5.57e-55 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MEFDBDGO_00657 2.06e-314 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
MEFDBDGO_00658 1.98e-281 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
MEFDBDGO_00659 1.27e-151 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
MEFDBDGO_00660 1.25e-39 - - - M - - - Lysin motif
MEFDBDGO_00661 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
MEFDBDGO_00662 3.38e-252 - - - S - - - Helix-turn-helix domain
MEFDBDGO_00663 4.34e-124 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MEFDBDGO_00664 2.69e-167 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
MEFDBDGO_00665 1.3e-132 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MEFDBDGO_00666 1.18e-174 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MEFDBDGO_00667 3.99e-92 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MEFDBDGO_00668 3.13e-211 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
MEFDBDGO_00669 7.94e-218 yitL - - S ko:K00243 - ko00000 S1 domain
MEFDBDGO_00670 2.51e-98 ytwI - - S - - - Protein of unknown function (DUF441)
MEFDBDGO_00671 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
MEFDBDGO_00672 8.69e-230 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MEFDBDGO_00673 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
MEFDBDGO_00674 2.02e-39 - - - S - - - Protein of unknown function (DUF2929)
MEFDBDGO_00675 0.0 clpB - - O ko:K03695 ko04213,map04213 ko00000,ko00001,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MEFDBDGO_00676 9.08e-299 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
MEFDBDGO_00677 3.25e-251 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MEFDBDGO_00678 8.34e-165 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
MEFDBDGO_00679 1.75e-295 - - - M - - - O-Antigen ligase
MEFDBDGO_00680 8.81e-166 drrB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
MEFDBDGO_00681 2.08e-213 drrA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
MEFDBDGO_00682 2.74e-112 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
MEFDBDGO_00683 0.0 pps 2.7.9.2 - H ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
MEFDBDGO_00684 2.27e-82 - - - P - - - Rhodanese Homology Domain
MEFDBDGO_00685 7.43e-119 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
MEFDBDGO_00686 3.9e-266 - - - - - - - -
MEFDBDGO_00687 5.21e-278 - - - I - - - transferase activity, transferring acyl groups other than amino-acyl groups
MEFDBDGO_00688 1.51e-232 - - - C - - - Zinc-binding dehydrogenase
MEFDBDGO_00689 0.0 - - - P - - - Cation transporter/ATPase, N-terminus
MEFDBDGO_00690 2.2e-310 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MEFDBDGO_00691 2.66e-306 - - - U ko:K18926 - ko00000,ko00002,ko02000 Major Facilitator Superfamily
MEFDBDGO_00692 4.38e-102 - - - K - - - Transcriptional regulator
MEFDBDGO_00693 7.87e-266 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
MEFDBDGO_00694 0.0 nox - - P - - - Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
MEFDBDGO_00695 1.68e-176 - - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
MEFDBDGO_00696 1.25e-140 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
MEFDBDGO_00697 2.65e-93 spx2 - - P ko:K16509 - ko00000 ArsC family
MEFDBDGO_00698 1.56e-90 - - - S - - - Protein of unknown function (DUF1722)
MEFDBDGO_00699 4.88e-147 - - - GM - - - epimerase
MEFDBDGO_00700 0.0 - - - S - - - Zinc finger, swim domain protein
MEFDBDGO_00701 5.04e-155 - 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 haloacid dehalogenase-like hydrolase
MEFDBDGO_00702 2.31e-132 thgA3 2.3.1.18, 2.3.1.79 - S ko:K00633,ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
MEFDBDGO_00703 2.49e-167 - - - K - - - Helix-turn-helix domain, rpiR family
MEFDBDGO_00704 6.46e-207 - - - S - - - Alpha beta hydrolase
MEFDBDGO_00705 5.89e-145 - - - GM - - - NmrA-like family
MEFDBDGO_00706 9.69e-99 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2255)
MEFDBDGO_00707 3.86e-205 - - - K - - - Transcriptional regulator
MEFDBDGO_00708 1.04e-218 cryZ 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 nadph quinone reductase
MEFDBDGO_00709 1.58e-21 - - - S - - - Alpha beta hydrolase
MEFDBDGO_00710 0.0 nox4 - - C - - - Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
MEFDBDGO_00711 9.11e-134 desR - - K ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, Lux Regulon
MEFDBDGO_00712 7.78e-261 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MEFDBDGO_00713 7.05e-172 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
MEFDBDGO_00714 4.87e-203 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
MEFDBDGO_00716 9.07e-107 - - - K ko:K03827 - ko00000,ko01000 Acetyltransferase (GNAT) domain
MEFDBDGO_00717 9.55e-95 - - - K - - - MarR family
MEFDBDGO_00718 1.49e-147 - - - S - - - Psort location CytoplasmicMembrane, score
MEFDBDGO_00719 4.36e-208 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MEFDBDGO_00720 2.11e-170 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
MEFDBDGO_00721 5.21e-254 - - - - - - - -
MEFDBDGO_00722 2.59e-256 - - - - - - - -
MEFDBDGO_00723 2.45e-213 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MEFDBDGO_00724 1.18e-85 ytrA - - K ko:K07979 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
MEFDBDGO_00725 1.74e-251 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MEFDBDGO_00726 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MEFDBDGO_00727 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
MEFDBDGO_00728 8.64e-224 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
MEFDBDGO_00729 2.84e-189 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
MEFDBDGO_00730 1.31e-215 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MEFDBDGO_00731 1.15e-94 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
MEFDBDGO_00732 7.7e-110 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MEFDBDGO_00733 4.81e-229 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
MEFDBDGO_00734 9.21e-94 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
MEFDBDGO_00735 1.09e-30 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
MEFDBDGO_00736 2.32e-194 yqfL 2.7.11.33, 2.7.4.28 - F ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MEFDBDGO_00737 3.65e-166 - - - C - - - Enoyl-(Acyl carrier protein) reductase
MEFDBDGO_00738 7.36e-220 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MEFDBDGO_00739 5.49e-286 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MEFDBDGO_00740 4.35e-204 yitT - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
MEFDBDGO_00741 2.61e-132 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MEFDBDGO_00742 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
MEFDBDGO_00743 2.47e-310 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
MEFDBDGO_00744 2.83e-200 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 N-acetylmuramoyl-L-alanine amidase
MEFDBDGO_00745 3.23e-214 - - - G - - - Fructosamine kinase
MEFDBDGO_00746 5.97e-151 yjcF - - J - - - HAD-hyrolase-like
MEFDBDGO_00747 8.2e-102 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MEFDBDGO_00748 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MEFDBDGO_00749 2.56e-76 - - - - - - - -
MEFDBDGO_00750 3.13e-172 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MEFDBDGO_00751 2.04e-226 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
MEFDBDGO_00752 1.11e-147 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
MEFDBDGO_00753 4.78e-65 - - - - - - - -
MEFDBDGO_00754 1.73e-67 - - - - - - - -
MEFDBDGO_00755 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MEFDBDGO_00756 1.38e-311 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MEFDBDGO_00757 5.75e-47 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MEFDBDGO_00758 1.14e-297 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
MEFDBDGO_00759 0.0 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MEFDBDGO_00760 8.49e-266 pbpX2 - - V - - - Beta-lactamase
MEFDBDGO_00761 2.54e-266 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MEFDBDGO_00762 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
MEFDBDGO_00763 4.94e-115 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MEFDBDGO_00764 4.42e-248 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MEFDBDGO_00765 1.19e-169 budA 4.1.1.5 - Q ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
MEFDBDGO_00766 7.56e-242 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
MEFDBDGO_00767 6.29e-221 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MEFDBDGO_00768 1.45e-114 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MEFDBDGO_00769 8.88e-248 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
MEFDBDGO_00770 8.18e-303 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MEFDBDGO_00771 1.63e-121 - - - - - - - -
MEFDBDGO_00772 9.01e-276 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MEFDBDGO_00773 0.0 - - - G - - - Major Facilitator
MEFDBDGO_00774 3.04e-71 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MEFDBDGO_00775 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MEFDBDGO_00776 5.46e-62 ylxQ - - J - - - ribosomal protein
MEFDBDGO_00777 2.95e-65 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
MEFDBDGO_00778 4.46e-275 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
MEFDBDGO_00779 9.74e-108 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
MEFDBDGO_00780 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MEFDBDGO_00781 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MEFDBDGO_00782 4.64e-294 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
MEFDBDGO_00783 1.13e-175 cdsA 2.7.7.41 - I ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
MEFDBDGO_00784 3.17e-190 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MEFDBDGO_00785 3.29e-111 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MEFDBDGO_00786 3.01e-165 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
MEFDBDGO_00787 7.66e-194 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MEFDBDGO_00788 6.33e-185 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
MEFDBDGO_00789 2.92e-172 - - - S ko:K07025 - ko00000 Haloacid dehalogenase-like hydrolase
MEFDBDGO_00790 1.92e-239 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MEFDBDGO_00791 1.02e-66 yazA - - L ko:K07461 - ko00000 GIY-YIG catalytic domain protein
MEFDBDGO_00792 1.14e-175 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
MEFDBDGO_00793 8.8e-155 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
MEFDBDGO_00794 3.96e-44 XK26_06720 - - S ko:K09976 - ko00000 Uncharacterised protein family (UPF0154)
MEFDBDGO_00795 7.68e-48 ynzC - - S - - - UPF0291 protein
MEFDBDGO_00796 7.22e-149 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MEFDBDGO_00797 7.8e-123 - - - - - - - -
MEFDBDGO_00798 1.56e-276 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
MEFDBDGO_00799 1.01e-100 - - - - - - - -
MEFDBDGO_00800 3.81e-87 - - - - - - - -
MEFDBDGO_00801 2.3e-226 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 Glycosyltransferase like family 2
MEFDBDGO_00802 2.19e-131 - - - L - - - Helix-turn-helix domain
MEFDBDGO_00803 1.89e-282 ywtF_2 - - K - - - Cell envelope-related transcriptional attenuator domain
MEFDBDGO_00804 1.1e-183 - - - P ko:K02049 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
MEFDBDGO_00805 0.0 - - - P ko:K02050 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MEFDBDGO_00806 2.38e-294 rodA - - D ko:K05837 - ko00000,ko03036 Cell cycle protein
MEFDBDGO_00808 5.03e-43 - - - - - - - -
MEFDBDGO_00809 1.62e-155 - - - Q - - - Methyltransferase
MEFDBDGO_00810 2.84e-75 ybjQ - - S - - - Belongs to the UPF0145 family
MEFDBDGO_00811 6.75e-269 - - - EGP - - - Major facilitator Superfamily
MEFDBDGO_00812 4.57e-135 - - - K - - - Helix-turn-helix domain
MEFDBDGO_00813 1.52e-120 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MEFDBDGO_00814 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
MEFDBDGO_00815 7.49e-67 - - - S - - - Lipopolysaccharide assembly protein A domain
MEFDBDGO_00816 7.09e-180 - - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
MEFDBDGO_00817 3.97e-226 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MEFDBDGO_00818 6.62e-62 - - - - - - - -
MEFDBDGO_00819 1.55e-311 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MEFDBDGO_00820 3.02e-175 fruR - - K ko:K03436 - ko00000,ko03000 DeoR C terminal sensor domain
MEFDBDGO_00821 1.73e-217 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
MEFDBDGO_00822 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase System
MEFDBDGO_00823 0.0 - 3.1.4.53 - S ko:K03651 ko00230,ko02025,map00230,map02025 ko00000,ko00001,ko01000 Calcineurin-like phosphoesterase
MEFDBDGO_00824 0.0 cps4J - - S - - - MatE
MEFDBDGO_00825 2.39e-228 cps4I - - M - - - Glycosyltransferase like family 2
MEFDBDGO_00826 1.01e-292 - - - - - - - -
MEFDBDGO_00827 1.34e-235 cps4G - - M - - - Glycosyltransferase Family 4
MEFDBDGO_00828 1.4e-259 cps4F - - M - - - Glycosyl transferases group 1
MEFDBDGO_00829 2.33e-164 tuaA - - M - - - Bacterial sugar transferase
MEFDBDGO_00830 2.5e-230 cps4D 5.1.3.2, 5.1.3.25 - M ko:K01784,ko:K17947 ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130 ko00000,ko00001,ko00002,ko01000 RmlD substrate binding domain
MEFDBDGO_00831 5.54e-189 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
MEFDBDGO_00832 4.08e-156 ywqD - - D - - - Capsular exopolysaccharide family
MEFDBDGO_00833 3.44e-161 epsB - - M - - - biosynthesis protein
MEFDBDGO_00834 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MEFDBDGO_00835 3.97e-173 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MEFDBDGO_00836 0.0 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
MEFDBDGO_00837 1.47e-30 - - - - - - - -
MEFDBDGO_00838 6.47e-95 - - - S - - - Iron-sulphur cluster biosynthesis
MEFDBDGO_00839 1.3e-65 - - - S - - - mazG nucleotide pyrophosphohydrolase
MEFDBDGO_00840 9.6e-143 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
MEFDBDGO_00841 7.8e-300 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MEFDBDGO_00842 6.48e-288 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MEFDBDGO_00843 4.38e-286 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MEFDBDGO_00844 5.89e-204 - - - S - - - Tetratricopeptide repeat
MEFDBDGO_00845 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MEFDBDGO_00846 1.29e-200 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MEFDBDGO_00847 3.84e-262 - - - EGP - - - Major Facilitator Superfamily
MEFDBDGO_00848 2.9e-56 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MEFDBDGO_00849 1.18e-46 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
MEFDBDGO_00850 8.43e-240 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
MEFDBDGO_00851 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
MEFDBDGO_00852 7.1e-116 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
MEFDBDGO_00853 2.56e-162 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
MEFDBDGO_00854 1.05e-251 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
MEFDBDGO_00855 2.99e-109 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MEFDBDGO_00856 4.98e-131 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
MEFDBDGO_00857 1.57e-65 ylbG - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
MEFDBDGO_00858 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MEFDBDGO_00859 2.51e-261 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
MEFDBDGO_00860 0.0 - - - - - - - -
MEFDBDGO_00861 0.0 icaA - - M - - - Glycosyl transferase family group 2
MEFDBDGO_00862 9.51e-135 - - - - - - - -
MEFDBDGO_00863 2.21e-257 - - - - - - - -
MEFDBDGO_00864 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
MEFDBDGO_00865 5e-177 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the inositol monophosphatase superfamily
MEFDBDGO_00866 2.64e-62 yktA - - S - - - Belongs to the UPF0223 family
MEFDBDGO_00867 2.15e-209 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 L-malate dehydrogenase activity
MEFDBDGO_00868 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
MEFDBDGO_00869 2.36e-285 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MEFDBDGO_00870 1.28e-229 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Transketolase, C-terminal domain protein
MEFDBDGO_00871 1.21e-268 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
MEFDBDGO_00872 3.95e-132 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MEFDBDGO_00873 6.45e-111 - - - - - - - -
MEFDBDGO_00874 4.86e-45 ykzG - - S - - - Belongs to the UPF0356 family
MEFDBDGO_00875 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MEFDBDGO_00876 4.9e-240 ytlR - - I - - - Diacylglycerol kinase catalytic domain
MEFDBDGO_00877 2.16e-39 - - - - - - - -
MEFDBDGO_00878 4.51e-163 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
MEFDBDGO_00879 3.09e-219 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MEFDBDGO_00880 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MEFDBDGO_00881 1.02e-155 - - - S - - - repeat protein
MEFDBDGO_00882 2.41e-157 pgm6 - - G - - - phosphoglycerate mutase
MEFDBDGO_00883 0.0 - - - N - - - domain, Protein
MEFDBDGO_00884 1e-247 - - - S - - - Bacterial protein of unknown function (DUF916)
MEFDBDGO_00885 4.17e-153 - - - N - - - WxL domain surface cell wall-binding
MEFDBDGO_00886 4.64e-150 ktrA - - P ko:K03499 - ko00000,ko02000 domain protein
MEFDBDGO_00887 9.64e-307 ktrB - - P ko:K03498 - ko00000,ko02000 Potassium uptake protein
MEFDBDGO_00888 1.53e-284 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MEFDBDGO_00889 4.94e-75 XK27_04120 - - S - - - Putative amino acid metabolism
MEFDBDGO_00890 3.69e-278 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
MEFDBDGO_00891 5.85e-158 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MEFDBDGO_00892 7.74e-47 - - - - - - - -
MEFDBDGO_00893 3.51e-125 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
MEFDBDGO_00894 3.46e-242 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MEFDBDGO_00895 2.05e-20 - - - S - - - Protein of unknown function (DUF3021)
MEFDBDGO_00896 5.18e-47 - - - K - - - LytTr DNA-binding domain
MEFDBDGO_00897 1.47e-100 - - - U ko:K11051 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 type transporter
MEFDBDGO_00898 3.64e-101 cylA - - V ko:K11050 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
MEFDBDGO_00899 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MEFDBDGO_00900 6.52e-124 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
MEFDBDGO_00901 2.06e-187 ylmH - - S - - - S4 domain protein
MEFDBDGO_00902 6.45e-49 ylmG - - S ko:K02221 - ko00000,ko02044 YGGT family
MEFDBDGO_00903 1.56e-93 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MEFDBDGO_00904 9.39e-295 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MEFDBDGO_00905 3.55e-312 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MEFDBDGO_00906 2.34e-208 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MEFDBDGO_00907 5e-253 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MEFDBDGO_00908 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MEFDBDGO_00909 2.81e-231 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MEFDBDGO_00910 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
MEFDBDGO_00911 7.01e-76 ftsL - - D - - - Cell division protein FtsL
MEFDBDGO_00912 2.12e-225 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MEFDBDGO_00913 1.35e-100 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
MEFDBDGO_00914 3.22e-82 - - - S - - - Protein of unknown function (DUF3397)
MEFDBDGO_00915 4.1e-223 - - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
MEFDBDGO_00916 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
MEFDBDGO_00917 1.66e-122 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MEFDBDGO_00918 1.44e-146 - - - S ko:K07118 - ko00000 NAD(P)H-binding
MEFDBDGO_00919 2.17e-302 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
MEFDBDGO_00921 1.12e-207 rrmA 2.1.1.187 - H ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 Methyltransferase
MEFDBDGO_00922 4.82e-55 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MEFDBDGO_00923 2.24e-262 XK27_05220 - - S - - - AI-2E family transporter
MEFDBDGO_00924 2.68e-75 srlB 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
MEFDBDGO_00925 5.57e-247 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
MEFDBDGO_00926 2.51e-150 cutC - - P ko:K06201 - ko00000 Participates in the control of copper homeostasis
MEFDBDGO_00927 1.09e-222 yjbO 5.4.99.23 - G ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
MEFDBDGO_00928 5.27e-193 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MEFDBDGO_00929 9.08e-157 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
MEFDBDGO_00930 2.24e-148 yjbH - - Q - - - Thioredoxin
MEFDBDGO_00931 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
MEFDBDGO_00932 2.34e-266 coiA - - S ko:K06198 - ko00000 Competence protein
MEFDBDGO_00933 7.12e-170 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
MEFDBDGO_00934 9.28e-89 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MEFDBDGO_00935 3.28e-177 yhfI - - S - - - Metallo-beta-lactamase superfamily
MEFDBDGO_00936 1.08e-117 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
MEFDBDGO_00937 4.5e-255 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
MEFDBDGO_00959 1.35e-55 - - - S - - - COG NOG38524 non supervised orthologous group
MEFDBDGO_00960 1.11e-84 - - - - - - - -
MEFDBDGO_00961 2e-98 yugI - - J ko:K07570,ko:K07571 - ko00000 general stress protein
MEFDBDGO_00962 5.16e-141 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MEFDBDGO_00963 7.18e-153 dedA - - S ko:K03975 - ko00000 SNARE-like domain protein
MEFDBDGO_00964 4.69e-151 - - - S - - - Protein of unknown function (DUF1461)
MEFDBDGO_00965 7.18e-189 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MEFDBDGO_00966 6.53e-115 yutD - - S - - - Protein of unknown function (DUF1027)
MEFDBDGO_00967 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
MEFDBDGO_00968 5.77e-151 - - - S - - - Calcineurin-like phosphoesterase
MEFDBDGO_00969 0.0 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
MEFDBDGO_00970 4.7e-282 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MEFDBDGO_00971 1.56e-236 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
MEFDBDGO_00973 6.46e-113 - - - S - - - Prokaryotic N-terminal methylation motif
MEFDBDGO_00974 1.02e-25 - - - - ko:K02671 - ko00000,ko02035,ko02044 -
MEFDBDGO_00975 1.5e-108 - - - NU ko:K02246 - ko00000,ko00002,ko02044 general secretion pathway protein
MEFDBDGO_00976 1.97e-72 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 competence protein ComGC
MEFDBDGO_00977 6.2e-242 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
MEFDBDGO_00978 1.55e-225 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
MEFDBDGO_00979 2.06e-205 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MEFDBDGO_00980 2.21e-168 yebC - - K - - - Transcriptional regulatory protein
MEFDBDGO_00981 2.44e-65 - - - S ko:K09004 - ko00000 DsrE/DsrF-like family
MEFDBDGO_00982 7.88e-211 - - - G - - - Xylose isomerase domain protein TIM barrel
MEFDBDGO_00983 5.44e-232 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
MEFDBDGO_00984 1.55e-275 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
MEFDBDGO_00985 9.11e-106 - - - K - - - helix_turn_helix, mercury resistance
MEFDBDGO_00986 1.6e-96 - - - - - - - -
MEFDBDGO_00987 1.88e-75 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MEFDBDGO_00988 2.31e-202 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
MEFDBDGO_00989 7.85e-288 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MEFDBDGO_00990 9.31e-112 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MEFDBDGO_00991 7.94e-114 ykuL - - S - - - (CBS) domain
MEFDBDGO_00992 2.62e-121 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
MEFDBDGO_00993 8.49e-144 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MEFDBDGO_00994 5.06e-194 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
MEFDBDGO_00995 1.45e-161 yslB - - S - - - Protein of unknown function (DUF2507)
MEFDBDGO_00996 3e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
MEFDBDGO_00997 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MEFDBDGO_00998 1.06e-49 - - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MEFDBDGO_00999 1.31e-63 yrzB - - S - - - Belongs to the UPF0473 family
MEFDBDGO_01000 5.39e-96 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MEFDBDGO_01001 5e-57 yrzL - - S - - - Belongs to the UPF0297 family
MEFDBDGO_01002 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MEFDBDGO_01003 2.79e-316 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MEFDBDGO_01004 8.32e-227 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
MEFDBDGO_01005 2.48e-276 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MEFDBDGO_01006 1.32e-63 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
MEFDBDGO_01007 2.84e-288 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MEFDBDGO_01008 5.87e-256 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MEFDBDGO_01009 2.62e-239 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MEFDBDGO_01010 2.83e-138 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MEFDBDGO_01011 2.07e-118 - - - - - - - -
MEFDBDGO_01012 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
MEFDBDGO_01013 1.35e-93 - - - - - - - -
MEFDBDGO_01014 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MEFDBDGO_01015 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MEFDBDGO_01016 6.18e-197 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 YmdB-like protein
MEFDBDGO_01017 6.57e-291 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
MEFDBDGO_01018 2.43e-264 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MEFDBDGO_01019 4.47e-294 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
MEFDBDGO_01020 1.92e-127 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MEFDBDGO_01021 5.74e-172 ymfM - - S ko:K15539 - ko00000 Helix-turn-helix domain
MEFDBDGO_01022 0.0 ymfH - - S - - - Peptidase M16
MEFDBDGO_01023 8.72e-297 ymfF - - S - - - Peptidase M16 inactive domain protein
MEFDBDGO_01024 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
MEFDBDGO_01025 2.61e-199 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
MEFDBDGO_01026 3.17e-149 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MEFDBDGO_01027 1.89e-141 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
MEFDBDGO_01028 1.23e-187 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
MEFDBDGO_01029 5.41e-150 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
MEFDBDGO_01030 9.47e-115 mreD - - M ko:K03571 - ko00000,ko03036 rod shape-determining protein MreD
MEFDBDGO_01031 3.76e-184 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
MEFDBDGO_01032 1.74e-211 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
MEFDBDGO_01033 1.15e-150 radC - - L ko:K03630 - ko00000 DNA repair protein
MEFDBDGO_01034 9.36e-317 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
MEFDBDGO_01035 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MEFDBDGO_01036 3.56e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MEFDBDGO_01037 4.5e-299 gshF 6.3.2.2 - H ko:K01919,ko:K16786,ko:K16787 ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the glutamate--cysteine ligase type 1 family
MEFDBDGO_01038 5e-252 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
MEFDBDGO_01039 7.66e-292 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MEFDBDGO_01040 2.22e-278 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
MEFDBDGO_01041 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MEFDBDGO_01042 5.28e-105 yebR 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
MEFDBDGO_01043 2.15e-137 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MEFDBDGO_01044 1.15e-144 yktB - - S - - - Belongs to the UPF0637 family
MEFDBDGO_01045 4e-105 XK27_05190 - - S - - - Protein of unknown function (DUF1694)
MEFDBDGO_01046 1.57e-142 - - - S - - - Protein of unknown function (DUF1648)
MEFDBDGO_01047 4.54e-59 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
MEFDBDGO_01048 7.24e-291 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
MEFDBDGO_01049 3.43e-55 - 2.7.1.191 - G ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
MEFDBDGO_01050 5.82e-139 - - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose fructose sorbose family IID component
MEFDBDGO_01051 4.54e-132 - - - G ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
MEFDBDGO_01052 3.79e-85 - 2.7.1.191 - G ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
MEFDBDGO_01053 1.31e-119 - - - K - - - Periplasmic binding proteins and sugar binding domain of LacI family
MEFDBDGO_01054 0.0 gshAB 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
MEFDBDGO_01055 2.96e-302 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
MEFDBDGO_01056 1.34e-52 - - - - - - - -
MEFDBDGO_01057 2.37e-107 uspA - - T - - - universal stress protein
MEFDBDGO_01058 1.91e-259 bla2 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
MEFDBDGO_01059 4.7e-207 - - - K - - - Helix-turn-helix XRE-family like proteins
MEFDBDGO_01060 0.0 glpQ3 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Glycerophosphoryl diester phosphodiesterase family
MEFDBDGO_01061 6.54e-273 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
MEFDBDGO_01062 7.55e-242 - 1.1.1.1, 1.6.5.5 - C ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
MEFDBDGO_01063 1.88e-226 - - - S - - - Protein of unknown function (DUF2785)
MEFDBDGO_01064 3.34e-215 hicD3 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
MEFDBDGO_01065 1.23e-190 metQ - - M ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
MEFDBDGO_01066 2.1e-151 metI - - U ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MEFDBDGO_01067 2.24e-239 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MEFDBDGO_01068 3.2e-64 gcsH2 - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 glycine cleavage
MEFDBDGO_01069 2.15e-280 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
MEFDBDGO_01070 2.54e-46 - - - S - - - Protein of unknown function (DUF2969)
MEFDBDGO_01071 1.52e-57 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
MEFDBDGO_01072 1.44e-230 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
MEFDBDGO_01073 1.68e-132 - - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
MEFDBDGO_01074 2.94e-315 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MEFDBDGO_01075 5.95e-74 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
MEFDBDGO_01076 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MEFDBDGO_01077 1.5e-208 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MEFDBDGO_01078 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MEFDBDGO_01079 2.03e-118 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MEFDBDGO_01080 5.41e-77 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MEFDBDGO_01081 1.81e-37 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MEFDBDGO_01082 4.82e-165 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
MEFDBDGO_01083 2.49e-294 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
MEFDBDGO_01084 7.81e-148 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MEFDBDGO_01085 3.04e-297 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MEFDBDGO_01086 1.79e-243 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MEFDBDGO_01087 5.96e-205 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MEFDBDGO_01088 1.88e-251 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MEFDBDGO_01089 1.54e-141 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
MEFDBDGO_01090 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Domain of unknown function (DUF1727)
MEFDBDGO_01091 1.83e-175 cobQ - - S ko:K07009 - ko00000 glutamine amidotransferase
MEFDBDGO_01092 4.95e-250 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
MEFDBDGO_01093 1.12e-246 ampC - - V - - - Beta-lactamase
MEFDBDGO_01094 2.88e-39 - - - - - - - -
MEFDBDGO_01095 1.9e-260 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
MEFDBDGO_01096 1.33e-77 - - - - - - - -
MEFDBDGO_01097 5.37e-182 - - - - - - - -
MEFDBDGO_01098 0.0 yfiC - - V ko:K06147 - ko00000,ko02000 ABC transporter
MEFDBDGO_01099 0.0 ycfI - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
MEFDBDGO_01100 5.63e-89 yxeA - - S - - - Protein of unknown function (DUF1093)
MEFDBDGO_01101 2.96e-182 icaB - - G - - - Polysaccharide deacetylase
MEFDBDGO_01104 1.98e-40 - - - - - - - -
MEFDBDGO_01106 1.28e-51 - - - - - - - -
MEFDBDGO_01107 9.28e-58 - - - - - - - -
MEFDBDGO_01108 1.27e-109 - - - K - - - MarR family
MEFDBDGO_01109 0.0 - - - D - - - nuclear chromosome segregation
MEFDBDGO_01110 0.0 inlJ - - M - - - MucBP domain
MEFDBDGO_01111 6.58e-24 - - - - - - - -
MEFDBDGO_01112 3.26e-24 - - - - - - - -
MEFDBDGO_01113 1.56e-22 - - - - - - - -
MEFDBDGO_01114 1.07e-26 - - - - - - - -
MEFDBDGO_01115 9.35e-24 - - - - - - - -
MEFDBDGO_01116 9.35e-24 - - - - - - - -
MEFDBDGO_01117 9.35e-24 - - - - - - - -
MEFDBDGO_01118 2.16e-26 - - - - - - - -
MEFDBDGO_01119 4.63e-24 - - - - - - - -
MEFDBDGO_01120 0.0 - 3.6.3.44 - P ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter transmembrane region
MEFDBDGO_01121 0.0 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
MEFDBDGO_01122 0.0 - - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MEFDBDGO_01123 2.1e-33 - - - - - - - -
MEFDBDGO_01124 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
MEFDBDGO_01125 2.51e-200 glcU - - U ko:K05340 - ko00000,ko02000 sugar transport
MEFDBDGO_01126 3.03e-276 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 S-adenosylmethionine-dependent methyltransferase
MEFDBDGO_01127 0.0 yclK - - T - - - Histidine kinase
MEFDBDGO_01128 1.45e-173 yclJ - - K ko:K02483 - ko00000,ko02022 response regulator
MEFDBDGO_01129 2.12e-308 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
MEFDBDGO_01130 1.06e-51 XK27_08630 - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
MEFDBDGO_01131 1.26e-218 - - - EG - - - EamA-like transporter family
MEFDBDGO_01133 6.24e-120 - - - S - - - ECF-type riboflavin transporter, S component
MEFDBDGO_01134 1.31e-64 - - - - - - - -
MEFDBDGO_01135 6.83e-274 yceI - - EGP ko:K08369 - ko00000,ko02000 Major Facilitator
MEFDBDGO_01136 2.31e-177 - - - F - - - NUDIX domain
MEFDBDGO_01137 2.68e-32 - - - - - - - -
MEFDBDGO_01139 8.16e-207 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
MEFDBDGO_01140 4.27e-223 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 NlpC/P60 family
MEFDBDGO_01141 4.17e-107 - - - K ko:K03719 - ko00000,ko03000,ko03036 AsnC family
MEFDBDGO_01142 2.29e-48 - - - - - - - -
MEFDBDGO_01143 1.11e-45 - - - - - - - -
MEFDBDGO_01144 2.81e-278 - - - T - - - diguanylate cyclase
MEFDBDGO_01145 0.0 - - - S - - - ABC transporter, ATP-binding protein
MEFDBDGO_01146 9.24e-140 - - - K ko:K06977 - ko00000 acetyltransferase
MEFDBDGO_01147 9.95e-108 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MEFDBDGO_01148 3.02e-253 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
MEFDBDGO_01149 9.2e-62 - - - - - - - -
MEFDBDGO_01150 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.208 - G ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
MEFDBDGO_01151 1.46e-239 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MEFDBDGO_01152 3.45e-209 - - - S - - - Uncharacterised protein, DegV family COG1307
MEFDBDGO_01153 1.01e-293 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Homoserine dehydrogenase
MEFDBDGO_01154 6.08e-312 metY 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
MEFDBDGO_01155 8.88e-213 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
MEFDBDGO_01156 1.13e-225 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
MEFDBDGO_01157 6.03e-196 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
MEFDBDGO_01158 1.32e-178 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MEFDBDGO_01159 0.0 npr 1.11.1.1 - C ko:K05910 - ko00000,ko01000 NADH oxidase
MEFDBDGO_01160 2.34e-203 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 Dehydrogenase
MEFDBDGO_01161 1.01e-176 yceF - - P ko:K05794 - ko00000 membrane
MEFDBDGO_01162 2.03e-124 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
MEFDBDGO_01163 1.34e-258 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MEFDBDGO_01164 1.07e-68 hisE 3.6.1.31 - E ko:K01523 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 phosphoribosyl-ATP diphosphatase activity
MEFDBDGO_01165 2.49e-77 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MEFDBDGO_01166 1.05e-171 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MEFDBDGO_01167 3.96e-165 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MEFDBDGO_01168 2.23e-142 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MEFDBDGO_01169 1e-138 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
MEFDBDGO_01170 1.57e-298 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MEFDBDGO_01171 1.69e-151 hisG 2.4.2.17 - F ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
MEFDBDGO_01172 1.33e-274 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MEFDBDGO_01173 6.46e-208 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Histidinol phosphate phosphatase, HisJ
MEFDBDGO_01174 3.05e-282 ysaA - - V - - - RDD family
MEFDBDGO_01175 7.28e-213 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
MEFDBDGO_01176 1.71e-67 - - - S - - - Domain of unknown function (DU1801)
MEFDBDGO_01177 2.54e-17 rmeB - - K - - - transcriptional regulator, MerR family
MEFDBDGO_01178 1.69e-255 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MEFDBDGO_01179 2.83e-238 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MEFDBDGO_01180 1.45e-46 - - - - - - - -
MEFDBDGO_01181 1.26e-143 - - - S - - - Protein of unknown function (DUF1211)
MEFDBDGO_01182 0.0 ydgH - - S ko:K06994 - ko00000 MMPL family
MEFDBDGO_01183 0.0 - - - M - - - domain protein
MEFDBDGO_01184 7.35e-99 yjcF - - S - - - Acetyltransferase (GNAT) domain
MEFDBDGO_01185 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MEFDBDGO_01186 0.0 glpQ4 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 phosphodiesterase
MEFDBDGO_01187 2.32e-235 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
MEFDBDGO_01188 2.14e-183 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
MEFDBDGO_01189 4.32e-247 - - - S - - - domain, Protein
MEFDBDGO_01190 6.04e-217 - - - S - - - Polyphosphate kinase 2 (PPK2)
MEFDBDGO_01191 2.57e-128 - - - C - - - Nitroreductase family
MEFDBDGO_01192 5.02e-228 iunH1 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 nucleoside hydrolase
MEFDBDGO_01193 2.43e-209 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MEFDBDGO_01194 1.91e-198 - - - U ko:K05340 - ko00000,ko02000 sugar transport
MEFDBDGO_01195 1.79e-92 - - - GK - - - ROK family
MEFDBDGO_01196 1.13e-112 - - - GK - - - ROK family
MEFDBDGO_01197 2.08e-199 - 1.97.1.4 - C ko:K04069 - ko00000,ko01000 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MEFDBDGO_01198 1.18e-172 rdrA - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
MEFDBDGO_01199 0.0 pflD 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 Pyruvate formate lyase-like
MEFDBDGO_01200 4.3e-228 - - - K - - - sugar-binding domain protein
MEFDBDGO_01201 1.81e-160 mipB 2.2.1.2 - H ko:K00616,ko:K08314 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase/Fructose-6-phosphate aldolase
MEFDBDGO_01202 2.13e-182 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
MEFDBDGO_01203 2.89e-224 ccpB - - K - - - lacI family
MEFDBDGO_01204 1.51e-202 - - - K - - - Helix-turn-helix domain, rpiR family
MEFDBDGO_01205 5e-227 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
MEFDBDGO_01206 1.89e-254 yhhX - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
MEFDBDGO_01207 0.0 nhaP2 - - P ko:K03316 - ko00000 Sodium proton antiporter
MEFDBDGO_01208 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MEFDBDGO_01209 1.33e-138 pncA - - Q - - - Isochorismatase family
MEFDBDGO_01210 2.66e-172 - - - - - - - -
MEFDBDGO_01211 5e-162 skfE - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
MEFDBDGO_01212 8.34e-86 lexA - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator, GntR family
MEFDBDGO_01213 7.2e-61 - - - S - - - Enterocin A Immunity
MEFDBDGO_01214 3.25e-223 ybcH - - D ko:K06889 - ko00000 Alpha beta
MEFDBDGO_01215 0.0 pepF2 - - E - - - Oligopeptidase F
MEFDBDGO_01216 1.4e-95 - - - K - - - Transcriptional regulator
MEFDBDGO_01217 1.53e-209 - - - - - - - -
MEFDBDGO_01218 1.23e-75 - - - - - - - -
MEFDBDGO_01219 1.44e-65 - - - - - - - -
MEFDBDGO_01220 0.0 spxB 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
MEFDBDGO_01221 4.09e-89 - - - - - - - -
MEFDBDGO_01222 1.19e-186 - - - S ko:K06889 - ko00000 Dienelactone hydrolase family
MEFDBDGO_01223 2.84e-73 ytpP - - CO - - - Thioredoxin
MEFDBDGO_01224 6.69e-263 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Cys/Met metabolism PLP-dependent enzyme
MEFDBDGO_01225 3.89e-62 - - - - - - - -
MEFDBDGO_01226 1.57e-71 - - - - - - - -
MEFDBDGO_01227 9.85e-106 - - - S - - - Protein of unknown function (DUF2798)
MEFDBDGO_01228 1.65e-97 - - - - - - - -
MEFDBDGO_01229 4.15e-78 - - - - - - - -
MEFDBDGO_01230 4.26e-250 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
MEFDBDGO_01231 0.0 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Bacterial SH3 domain
MEFDBDGO_01232 1.63e-95 - - - G ko:K02744 ko00052,ko02060,map00052,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
MEFDBDGO_01233 3.82e-188 agaD - - G ko:K02747,ko:K02796,ko:K10986 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
MEFDBDGO_01234 5.2e-185 - - - G ko:K02746,ko:K10985 ko00052,ko02060,map00052,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
MEFDBDGO_01235 1.49e-112 - 2.7.1.191 - K ko:K02745,ko:K02794,ko:K10984 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
MEFDBDGO_01236 5.87e-166 - - - K ko:K03710 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
MEFDBDGO_01237 2.51e-103 uspA3 - - T - - - universal stress protein
MEFDBDGO_01238 1.84e-205 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
MEFDBDGO_01239 4.05e-64 - - - K - - - Cro/C1-type HTH DNA-binding domain
MEFDBDGO_01240 1.38e-30 - - - S - - - Protein of unknown function (DUF2929)
MEFDBDGO_01241 3.07e-284 - - - M - - - Glycosyl transferases group 1
MEFDBDGO_01242 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
MEFDBDGO_01243 3.74e-205 - - - S - - - Putative esterase
MEFDBDGO_01244 3.53e-169 - - - K - - - Transcriptional regulator
MEFDBDGO_01245 4.75e-117 ybaK - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MEFDBDGO_01246 1.74e-178 - - - - - - - -
MEFDBDGO_01247 4.85e-151 yagB - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
MEFDBDGO_01248 8.05e-179 rrp8 - - K - - - LytTr DNA-binding domain
MEFDBDGO_01249 1.7e-118 - - - K - - - Domain of unknown function (DUF1836)
MEFDBDGO_01250 5.4e-80 - - - - - - - -
MEFDBDGO_01251 7.48e-96 hsp2 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
MEFDBDGO_01252 2.97e-76 - - - - - - - -
MEFDBDGO_01253 0.0 yhdP - - S - - - Transporter associated domain
MEFDBDGO_01254 1.18e-114 nrdI - - F ko:K03647 - ko00000 Belongs to the NrdI family
MEFDBDGO_01255 0.0 nhaP3 - - P ko:K03316 - ko00000 Sodium proton antiporter
MEFDBDGO_01256 1.17e-270 yttB - - EGP - - - Major Facilitator
MEFDBDGO_01257 4.71e-81 - - - K - - - helix_turn_helix, mercury resistance
MEFDBDGO_01258 8.91e-220 - - - C - - - Zinc-binding dehydrogenase
MEFDBDGO_01259 4.71e-74 - - - S - - - SdpI/YhfL protein family
MEFDBDGO_01260 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MEFDBDGO_01261 0.0 gabR - - K ko:K00375 - ko00000,ko03000 Bacterial regulatory proteins, gntR family
MEFDBDGO_01262 2.91e-277 araT2 - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
MEFDBDGO_01263 1.46e-131 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MEFDBDGO_01264 3.59e-26 - - - - - - - -
MEFDBDGO_01265 2.09e-169 - - - S ko:K07090 - ko00000 membrane transporter protein
MEFDBDGO_01266 5.73e-208 mleR - - K - - - LysR family
MEFDBDGO_01267 1.29e-148 - - - GM - - - NAD(P)H-binding
MEFDBDGO_01268 3.86e-124 - - - K - - - Acetyltransferase (GNAT) family
MEFDBDGO_01269 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
MEFDBDGO_01270 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
MEFDBDGO_01271 5.46e-218 oroP - - S ko:K09936 ko02024,map02024 ko00000,ko00001,ko02000 Putative inner membrane exporter, YdcZ
MEFDBDGO_01272 6.64e-146 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MEFDBDGO_01273 1.09e-161 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MEFDBDGO_01274 4.24e-218 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MEFDBDGO_01275 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
MEFDBDGO_01276 2.36e-272 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
MEFDBDGO_01277 1.95e-309 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MEFDBDGO_01278 1.22e-220 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
MEFDBDGO_01279 7.13e-123 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MEFDBDGO_01280 0.0 pucR_2 - - QT ko:K09684 - ko00000,ko03000 Purine catabolism regulatory protein-like family
MEFDBDGO_01281 3.1e-305 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
MEFDBDGO_01282 5.67e-280 pbuG - - S ko:K06901 - ko00000,ko02000 Permease family
MEFDBDGO_01283 2.24e-206 - - - GM - - - NmrA-like family
MEFDBDGO_01284 1.25e-199 - - - T - - - EAL domain
MEFDBDGO_01285 2.62e-121 - - - - - - - -
MEFDBDGO_01286 0.0 yijG - GT2 M ko:K11936 ko02026,map02026 ko00000,ko00001,ko01000,ko01003,ko02000 Glycosyl transferase
MEFDBDGO_01287 1.99e-161 - - - E - - - Methionine synthase
MEFDBDGO_01288 2.71e-280 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
MEFDBDGO_01289 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
MEFDBDGO_01290 5.35e-133 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MEFDBDGO_01291 5.35e-246 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
MEFDBDGO_01292 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MEFDBDGO_01293 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MEFDBDGO_01294 6.91e-164 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MEFDBDGO_01295 1.17e-55 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MEFDBDGO_01296 3.39e-168 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
MEFDBDGO_01297 1e-270 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MEFDBDGO_01298 3.77e-104 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MEFDBDGO_01299 5.19e-310 XK27_09615 1.5.1.36 - S ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 reductase
MEFDBDGO_01300 9.92e-143 - - - S - - - NADPH-dependent FMN reductase
MEFDBDGO_01301 1.16e-242 lplL 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Bacterial lipoate protein ligase C-terminus
MEFDBDGO_01302 2.04e-189 ptp3 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
MEFDBDGO_01303 3.44e-152 cah 4.2.1.1 - P ko:K01674 ko00910,map00910 ko00000,ko00001,ko01000 Eukaryotic-type carbonic anhydrase
MEFDBDGO_01304 4.15e-191 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
MEFDBDGO_01305 3.7e-233 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 Asparaginase
MEFDBDGO_01306 2.05e-178 cysA - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MEFDBDGO_01307 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
MEFDBDGO_01308 4.76e-56 - - - - - - - -
MEFDBDGO_01309 8.2e-81 - - - K - - - Transcriptional regulator, GntR family
MEFDBDGO_01310 7.89e-212 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MEFDBDGO_01311 5.66e-189 - - - - - - - -
MEFDBDGO_01312 2.7e-104 usp5 - - T - - - universal stress protein
MEFDBDGO_01313 1.08e-47 - - - - - - - -
MEFDBDGO_01314 4.02e-95 gtcA - - S - - - Teichoic acid glycosylation protein
MEFDBDGO_01315 1.02e-113 - - - - - - - -
MEFDBDGO_01316 1.98e-65 - - - - - - - -
MEFDBDGO_01317 4.79e-13 - - - - - - - -
MEFDBDGO_01318 3.03e-299 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
MEFDBDGO_01319 1.16e-110 - - - F - - - belongs to the nudix hydrolase family
MEFDBDGO_01320 1.52e-151 - - - - - - - -
MEFDBDGO_01321 1.21e-69 - - - - - - - -
MEFDBDGO_01323 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
MEFDBDGO_01324 0.0 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
MEFDBDGO_01325 4.65e-186 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
MEFDBDGO_01326 1.18e-40 - - - S - - - Pentapeptide repeats (8 copies)
MEFDBDGO_01327 1.76e-143 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
MEFDBDGO_01328 5.38e-131 - 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
MEFDBDGO_01329 2.26e-91 - - - FG - - - Scavenger mRNA decapping enzyme C-term binding
MEFDBDGO_01330 1.62e-173 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
MEFDBDGO_01331 3.94e-49 XK27_01315 - - S - - - Protein of unknown function (DUF2829)
MEFDBDGO_01332 3.48e-269 ybhE - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
MEFDBDGO_01333 4.43e-294 - - - S - - - Sterol carrier protein domain
MEFDBDGO_01334 1.66e-287 - - - EGP - - - Transmembrane secretion effector
MEFDBDGO_01335 3.74e-115 yrxA - - S ko:K07105 - ko00000 3H domain
MEFDBDGO_01336 0.0 nadC2 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MEFDBDGO_01337 2.13e-152 - - - K - - - Transcriptional regulator
MEFDBDGO_01338 9.76e-234 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
MEFDBDGO_01339 4.29e-173 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
MEFDBDGO_01340 0.0 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
MEFDBDGO_01341 0.0 pbg4 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MEFDBDGO_01342 0.0 pbg5 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MEFDBDGO_01343 2.73e-73 celC 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose Cellobiose specific IIA subunit
MEFDBDGO_01344 1.86e-64 pts20B 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
MEFDBDGO_01345 6.37e-169 gntR - - K ko:K03489 - ko00000,ko03000 UTRA
MEFDBDGO_01346 1.4e-181 epsV - - S - - - glycosyl transferase family 2
MEFDBDGO_01347 1.75e-156 pgm7 - - G - - - Phosphoglycerate mutase family
MEFDBDGO_01348 7.63e-107 - - - - - - - -
MEFDBDGO_01349 5.06e-196 - - - S - - - hydrolase
MEFDBDGO_01350 1.51e-235 ykpB 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MEFDBDGO_01351 2.8e-204 - - - EG - - - EamA-like transporter family
MEFDBDGO_01352 4.12e-226 serA1 - - EH - - - D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
MEFDBDGO_01353 3.78e-132 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
MEFDBDGO_01354 0.0 - - - - ko:K21471 - ko00000,ko01000,ko01002,ko01011 -
MEFDBDGO_01355 6.75e-101 fld - - C ko:K03839 - ko00000 Flavodoxin
MEFDBDGO_01356 0.0 - - - M - - - Domain of unknown function (DUF5011)
MEFDBDGO_01357 0.0 - - - M - - - Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
MEFDBDGO_01358 4.3e-44 - - - - - - - -
MEFDBDGO_01359 4.11e-165 aroC1 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Type I 3-dehydroquinase
MEFDBDGO_01360 0.0 ycaM - - E - - - amino acid
MEFDBDGO_01361 2.45e-101 - - - K - - - Winged helix DNA-binding domain
MEFDBDGO_01362 1.42e-212 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 Oxidoreductase, aldo keto reductase family protein
MEFDBDGO_01363 5.11e-208 akr5f 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
MEFDBDGO_01364 1.3e-209 - - - K - - - Transcriptional regulator
MEFDBDGO_01366 1.35e-55 - - - S - - - COG NOG38524 non supervised orthologous group
MEFDBDGO_01367 1.97e-110 - - - S - - - Pfam:DUF3816
MEFDBDGO_01368 7.01e-306 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MEFDBDGO_01369 1.27e-143 - - - - - - - -
MEFDBDGO_01370 4.39e-229 - - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
MEFDBDGO_01371 1.1e-184 - - - S - - - Peptidase_C39 like family
MEFDBDGO_01372 1.04e-120 - - - S - - - Protein of unknown function (DUF1694)
MEFDBDGO_01373 3.38e-150 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
MEFDBDGO_01374 9.79e-191 - - - KT - - - helix_turn_helix, mercury resistance
MEFDBDGO_01375 3.41e-295 gltT - - U ko:K03309,ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MEFDBDGO_01376 1.86e-123 - - - S ko:K08996 - ko00000 Protein of unknown function (DUF1440)
MEFDBDGO_01377 1.2e-240 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
MEFDBDGO_01378 7.14e-157 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MEFDBDGO_01379 2.76e-117 - - - T ko:K16923 - ko00000,ko00002,ko02000 phosphorelay sensor kinase activity
MEFDBDGO_01380 2e-238 iunH3 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Inosine-uridine preferring nucleoside hydrolase
MEFDBDGO_01381 3.55e-127 ywjB - - H - - - RibD C-terminal domain
MEFDBDGO_01382 1.97e-258 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MEFDBDGO_01383 9.01e-155 - - - S - - - Membrane
MEFDBDGO_01384 2.11e-199 mleP3 - - S ko:K07088 - ko00000 Membrane transport protein
MEFDBDGO_01385 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Fumarase C C-terminus
MEFDBDGO_01386 3.04e-261 - - - EGP - - - Major Facilitator Superfamily
MEFDBDGO_01387 7.22e-163 - 3.8.1.2 - S ko:K01560 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
MEFDBDGO_01388 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
MEFDBDGO_01389 4.03e-104 - - - S - - - Domain of unknown function (DUF4811)
MEFDBDGO_01390 8.99e-133 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
MEFDBDGO_01391 4.38e-222 - - - S - - - Conserved hypothetical protein 698
MEFDBDGO_01392 2.06e-194 rlrG - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
MEFDBDGO_01393 0.0 tagE5 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Poly(Glycerol-phosphate) alpha-glucosyltransferase
MEFDBDGO_01394 0.0 tagE6 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
MEFDBDGO_01396 4.96e-88 - - - M - - - LysM domain
MEFDBDGO_01397 1.6e-119 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Methyltransferase
MEFDBDGO_01398 4.23e-215 natA - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MEFDBDGO_01399 7.88e-269 natB - - CP ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
MEFDBDGO_01400 6.27e-166 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
MEFDBDGO_01401 1.16e-72 cmd 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
MEFDBDGO_01402 4.77e-100 yphH - - S - - - Cupin domain
MEFDBDGO_01403 7.37e-103 - - - K - - - transcriptional regulator, MerR family
MEFDBDGO_01404 5.3e-302 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
MEFDBDGO_01405 0.0 ylbB - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
MEFDBDGO_01406 1.74e-156 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MEFDBDGO_01408 2.93e-151 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MEFDBDGO_01409 3.18e-141 thgA3 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
MEFDBDGO_01410 1.03e-150 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
MEFDBDGO_01411 2.82e-110 - - - - - - - -
MEFDBDGO_01412 5.14e-111 yvbK - - K - - - GNAT family
MEFDBDGO_01413 2.8e-49 - - - - - - - -
MEFDBDGO_01414 2.81e-64 - - - - - - - -
MEFDBDGO_01415 5.46e-145 pgm8 - - G - - - Histidine phosphatase superfamily (branch 1)
MEFDBDGO_01416 5.01e-82 - - - S - - - Domain of unknown function (DUF4440)
MEFDBDGO_01417 6.67e-204 - - - K - - - LysR substrate binding domain
MEFDBDGO_01418 2.53e-134 - - - GM - - - NAD(P)H-binding
MEFDBDGO_01419 2.03e-248 adh2 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
MEFDBDGO_01420 5.85e-194 - - - IQ - - - Enoyl-(Acyl carrier protein) reductase
MEFDBDGO_01421 1.2e-181 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
MEFDBDGO_01422 4.83e-105 - - - S - - - Protein of unknown function (DUF1211)
MEFDBDGO_01423 2.14e-98 - - - C - - - Flavodoxin
MEFDBDGO_01424 2.78e-160 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 reductase
MEFDBDGO_01425 1.43e-114 - - - U ko:K05340 - ko00000,ko02000 sugar transport
MEFDBDGO_01426 9.08e-112 - - - GM - - - NAD(P)H-binding
MEFDBDGO_01427 2.11e-132 akr5f 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
MEFDBDGO_01428 5.63e-98 - - - K - - - Transcriptional regulator
MEFDBDGO_01430 1.03e-31 - - - C - - - Flavodoxin
MEFDBDGO_01431 1.69e-08 adhR - - K - - - helix_turn_helix, mercury resistance
MEFDBDGO_01432 9.99e-147 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
MEFDBDGO_01433 2.41e-165 - - - C - - - Aldo keto reductase
MEFDBDGO_01434 4.02e-181 akr5f 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
MEFDBDGO_01435 3.08e-178 - - - EGP ko:K08166 - ko00000,ko02000 Major Facilitator Superfamily
MEFDBDGO_01436 5.55e-106 - - - GM - - - NAD(P)H-binding
MEFDBDGO_01437 2.1e-99 - - - T - - - Belongs to the universal stress protein A family
MEFDBDGO_01438 1.04e-124 maa 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
MEFDBDGO_01439 3.04e-163 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
MEFDBDGO_01440 5.69e-80 - - - - - - - -
MEFDBDGO_01441 5.52e-133 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
MEFDBDGO_01442 3.31e-283 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
MEFDBDGO_01443 1.86e-132 - - - M - - - Protein of unknown function (DUF3737)
MEFDBDGO_01444 1.48e-248 - - - C - - - Aldo/keto reductase family
MEFDBDGO_01446 0.0 mdlB - - V ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MEFDBDGO_01447 0.0 mdlA - - V ko:K06148,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MEFDBDGO_01448 1.83e-313 - - - EGP - - - Major Facilitator
MEFDBDGO_01451 1.24e-229 yhgE - - V ko:K01421 - ko00000 domain protein
MEFDBDGO_01452 3.01e-124 - - - K - - - Transcriptional regulator (TetR family)
MEFDBDGO_01453 6.88e-71 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
MEFDBDGO_01454 4.17e-195 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
MEFDBDGO_01455 2.81e-134 yokL3 - - J - - - Acetyltransferase (GNAT) domain
MEFDBDGO_01456 7.2e-125 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
MEFDBDGO_01457 9.53e-284 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
MEFDBDGO_01458 0.0 ykpA - - S - - - ABC transporter, ATP-binding protein
MEFDBDGO_01459 4.68e-190 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
MEFDBDGO_01460 0.0 - - - S - - - Predicted membrane protein (DUF2207)
MEFDBDGO_01461 0.0 uvrA3 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 excinuclease ABC
MEFDBDGO_01462 2.33e-265 - - - EGP - - - Major facilitator Superfamily
MEFDBDGO_01463 2.67e-220 ropB - - K - - - Helix-turn-helix XRE-family like proteins
MEFDBDGO_01464 1.45e-297 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 Vacuole effluxer Atg22 like
MEFDBDGO_01465 0.0 npp - - S - - - type I phosphodiesterase nucleotide pyrophosphatase
MEFDBDGO_01466 6.45e-203 - - - I - - - alpha/beta hydrolase fold
MEFDBDGO_01467 3.39e-166 treR - - K ko:K03486 - ko00000,ko03000 UTRA
MEFDBDGO_01468 0.0 - - - - - - - -
MEFDBDGO_01469 2e-52 - - - S - - - Cytochrome B5
MEFDBDGO_01470 8.33e-116 pts21A - - G ko:K02755 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
MEFDBDGO_01471 2.05e-279 - - - T - - - Diguanylate cyclase, GGDEF domain
MEFDBDGO_01472 2.82e-163 - - - T - - - Putative diguanylate phosphodiesterase
MEFDBDGO_01473 3.83e-135 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MEFDBDGO_01474 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
MEFDBDGO_01475 2.59e-107 - - - - - - - -
MEFDBDGO_01476 5.97e-96 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
MEFDBDGO_01477 5.32e-242 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MEFDBDGO_01478 2.09e-244 dus - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MEFDBDGO_01479 3.7e-30 - - - - - - - -
MEFDBDGO_01480 1.84e-134 - - - - - - - -
MEFDBDGO_01481 5.12e-212 - - - K - - - LysR substrate binding domain
MEFDBDGO_01482 1.24e-313 - - - P - - - Sodium:sulfate symporter transmembrane region
MEFDBDGO_01483 0.0 - 4.1.1.98 - H ko:K03182 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
MEFDBDGO_01484 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
MEFDBDGO_01485 3.93e-182 - - - S - - - zinc-ribbon domain
MEFDBDGO_01487 4.29e-50 - - - - - - - -
MEFDBDGO_01488 1.27e-146 - - - S ko:K06889 - ko00000 Alpha/beta hydrolase family
MEFDBDGO_01489 6.74e-231 - - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
MEFDBDGO_01490 0.0 - - - I - - - acetylesterase activity
MEFDBDGO_01491 1.21e-298 - - - M - - - Collagen binding domain
MEFDBDGO_01492 1.15e-204 yicL - - EG - - - EamA-like transporter family
MEFDBDGO_01493 3.03e-166 - - - E - - - lipolytic protein G-D-S-L family
MEFDBDGO_01494 1.44e-226 - 4.1.1.52 - S ko:K22213 - ko00000,ko01000 Amidohydrolase
MEFDBDGO_01495 1.98e-142 - - - K - - - Transcriptional regulator C-terminal region
MEFDBDGO_01496 8.76e-63 - - - K - - - HxlR-like helix-turn-helix
MEFDBDGO_01497 1.07e-206 ypbG 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
MEFDBDGO_01498 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
MEFDBDGO_01499 5.24e-124 - - - K - - - Transcriptional regulator, MarR family
MEFDBDGO_01500 8.08e-154 ydgI3 - - C - - - Nitroreductase family
MEFDBDGO_01501 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.208 - G ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
MEFDBDGO_01502 6.24e-152 - - - S ko:K05833 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
MEFDBDGO_01503 2.48e-199 WQ51_06230 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
MEFDBDGO_01504 7.28e-218 XK27_00670 - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
MEFDBDGO_01505 0.0 - - - - - - - -
MEFDBDGO_01506 1.2e-83 - - - - - - - -
MEFDBDGO_01507 9.55e-243 - - - S - - - Cell surface protein
MEFDBDGO_01508 1.27e-137 - - - S - - - WxL domain surface cell wall-binding
MEFDBDGO_01509 1.91e-124 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
MEFDBDGO_01510 7.96e-158 livF - - E ko:K01996 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter
MEFDBDGO_01511 1.28e-180 livG - - E ko:K01995 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid ATP-binding cassette transporter
MEFDBDGO_01512 7.65e-192 livM - - E ko:K01997,ko:K01998 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid transport system / permease component
MEFDBDGO_01513 9.73e-197 livH - - U ko:K01997 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid transport system / permease component
MEFDBDGO_01514 2.1e-269 livJ - - E ko:K01999 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Receptor family ligand binding region
MEFDBDGO_01516 1.15e-43 - - - - - - - -
MEFDBDGO_01517 6.9e-168 zmp3 - - O - - - Zinc-dependent metalloprotease
MEFDBDGO_01518 2.88e-106 gtcA3 - - S - - - GtrA-like protein
MEFDBDGO_01519 4.08e-158 - - - K - - - Helix-turn-helix XRE-family like proteins
MEFDBDGO_01520 0.0 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
MEFDBDGO_01521 1.18e-94 usp2 - - T - - - Belongs to the universal stress protein A family
MEFDBDGO_01522 2.87e-61 - - - - - - - -
MEFDBDGO_01523 1.81e-150 - - - S - - - SNARE associated Golgi protein
MEFDBDGO_01524 8.58e-65 czrA - - K ko:K22043 - ko00000,ko03000 Transcriptional regulator, ArsR family
MEFDBDGO_01525 7.89e-124 - - - P - - - Cadmium resistance transporter
MEFDBDGO_01526 0.0 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MEFDBDGO_01527 0.0 - - - P - - - Concanavalin A-like lectin/glucanases superfamily
MEFDBDGO_01528 2.03e-84 - - - - - - - -
MEFDBDGO_01529 1.93e-205 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
MEFDBDGO_01530 2.86e-72 - - - - - - - -
MEFDBDGO_01531 1.02e-193 - - - K - - - Helix-turn-helix domain
MEFDBDGO_01532 3.91e-100 pts23A - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
MEFDBDGO_01533 7.47e-70 ptcB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
MEFDBDGO_01534 0.0 pts23C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MEFDBDGO_01535 0.0 pbg6 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MEFDBDGO_01536 7.48e-236 - - - GM - - - Male sterility protein
MEFDBDGO_01537 4.4e-101 - - - K - - - helix_turn_helix, mercury resistance
MEFDBDGO_01538 4.61e-101 - - - M - - - LysM domain
MEFDBDGO_01539 3.03e-130 - - - M - - - Lysin motif
MEFDBDGO_01540 1.4e-138 - - - S - - - SdpI/YhfL protein family
MEFDBDGO_01541 1.58e-72 nudA - - S - - - ASCH
MEFDBDGO_01542 5.76e-212 psaA - - P ko:K02077,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
MEFDBDGO_01543 3.57e-120 - - - - - - - -
MEFDBDGO_01544 1.92e-155 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Methyladenine glycosylase
MEFDBDGO_01545 3.55e-281 - - - T - - - diguanylate cyclase
MEFDBDGO_01546 7.43e-97 - - - S - - - Psort location Cytoplasmic, score
MEFDBDGO_01547 0.0 umuC - - L ko:K03502 - ko00000,ko03400 impB/mucB/samB family C-terminal domain
MEFDBDGO_01548 1.17e-214 - - - K - - - Bacterial regulatory helix-turn-helix protein, lysR family
MEFDBDGO_01549 5.26e-96 - - - - - - - -
MEFDBDGO_01550 6.54e-168 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
MEFDBDGO_01551 5.37e-222 - - - C - - - C4-dicarboxylate transmembrane transporter activity
MEFDBDGO_01552 2.51e-150 - - - GM - - - NAD(P)H-binding
MEFDBDGO_01553 1.6e-118 - - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
MEFDBDGO_01554 5.51e-101 yphH - - S - - - Cupin domain
MEFDBDGO_01555 2.06e-78 - - - I - - - sulfurtransferase activity
MEFDBDGO_01556 5.44e-178 gdh 1.1.1.47, 1.1.1.53 - IQ ko:K00034,ko:K00038 ko00030,ko00140,ko01100,ko01120,ko01200,map00030,map00140,map01100,map01120,map01200 ko00000,ko00001,ko01000 reductase
MEFDBDGO_01557 8.38e-152 - - - GM - - - NAD(P)H-binding
MEFDBDGO_01558 2.31e-277 - - - - - - - -
MEFDBDGO_01559 0.0 - - - V ko:K06147,ko:K18892 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MEFDBDGO_01560 0.0 XK27_09600 - - V ko:K06147,ko:K18891 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MEFDBDGO_01561 1.3e-226 - - - O - - - protein import
MEFDBDGO_01562 1.67e-292 amd - - E - - - Peptidase family M20/M25/M40
MEFDBDGO_01563 2.43e-208 yhxD - - IQ - - - KR domain
MEFDBDGO_01565 9.38e-91 - - - - - - - -
MEFDBDGO_01566 5.2e-187 - - - K - - - Helix-turn-helix XRE-family like proteins
MEFDBDGO_01567 0.0 - - - E - - - Amino Acid
MEFDBDGO_01568 1.67e-86 lysM - - M - - - LysM domain
MEFDBDGO_01569 2.84e-284 dhaT 1.1.1.202 - C ko:K00086 ko00561,ko00640,map00561,map00640 ko00000,ko00001,ko01000 Dehydrogenase
MEFDBDGO_01570 6.8e-272 adhC 1.1.1.90 - C ko:K00055 ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Zn-dependent alcohol dehydrogenases, class III
MEFDBDGO_01571 0.0 copA 3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54 - P ko:K01533,ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
MEFDBDGO_01572 1.49e-58 - - - S - - - Cupredoxin-like domain
MEFDBDGO_01573 1.36e-84 - - - S - - - Cupredoxin-like domain
MEFDBDGO_01574 0.0 aapA - - M - - - Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
MEFDBDGO_01575 2.81e-181 - - - K - - - Helix-turn-helix domain
MEFDBDGO_01576 1.47e-51 - - - S ko:K07343 - ko00000 TfoX C-terminal domain
MEFDBDGO_01577 3.05e-289 hpk9 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
MEFDBDGO_01578 0.0 - - - - - - - -
MEFDBDGO_01579 3.15e-98 - - - - - - - -
MEFDBDGO_01580 2.85e-243 - - - S - - - Cell surface protein
MEFDBDGO_01581 6.02e-137 - - - S - - - WxL domain surface cell wall-binding
MEFDBDGO_01582 4.62e-226 - - - C - - - Alcohol dehydrogenase GroES-like domain
MEFDBDGO_01583 1.27e-90 - - - S - - - Iron-sulphur cluster biosynthesis
MEFDBDGO_01584 1.36e-148 - - - S - - - GyrI-like small molecule binding domain
MEFDBDGO_01585 1.52e-241 ynjC - - S - - - Cell surface protein
MEFDBDGO_01586 4.48e-130 - - - S - - - WxL domain surface cell wall-binding
MEFDBDGO_01587 1.47e-83 - - - - - - - -
MEFDBDGO_01588 2.1e-300 - - - NU - - - Mycoplasma protein of unknown function, DUF285
MEFDBDGO_01589 4.8e-156 - - - - - - - -
MEFDBDGO_01590 4.31e-149 - - - S - - - Haloacid dehalogenase-like hydrolase
MEFDBDGO_01591 3.25e-81 ytcD - - K - - - Transcriptional regulator, HxlR family
MEFDBDGO_01592 1.81e-272 - - - EGP - - - Major Facilitator
MEFDBDGO_01593 4.52e-147 - - - M - - - ErfK YbiS YcfS YnhG
MEFDBDGO_01594 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
MEFDBDGO_01595 1.38e-174 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
MEFDBDGO_01596 1.77e-282 blpH 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
MEFDBDGO_01597 1.59e-130 - - - K - - - Bacterial regulatory proteins, tetR family
MEFDBDGO_01598 2.65e-216 - - - GM - - - NmrA-like family
MEFDBDGO_01599 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
MEFDBDGO_01600 0.0 - - - M - - - Glycosyl hydrolases family 25
MEFDBDGO_01601 1.62e-62 - - - S - - - Domain of unknown function (DUF1905)
MEFDBDGO_01602 1.27e-83 - - - K - - - HxlR-like helix-turn-helix
MEFDBDGO_01603 3.27e-170 - - - S - - - KR domain
MEFDBDGO_01604 2.46e-127 - - - K - - - Bacterial regulatory proteins, tetR family
MEFDBDGO_01605 3.47e-244 - 1.1.1.219 - GM ko:K00091 - ko00000,ko01000 Male sterility protein
MEFDBDGO_01606 1.09e-130 - - - S - - - Protein of unknown function (DUF1211)
MEFDBDGO_01607 1.97e-229 ydhF - - S - - - Aldo keto reductase
MEFDBDGO_01608 0.0 yfjF - - U - - - Sugar (and other) transporter
MEFDBDGO_01609 2.64e-141 - - - K - - - Bacterial regulatory proteins, tetR family
MEFDBDGO_01610 1.22e-219 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
MEFDBDGO_01611 6.37e-188 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
MEFDBDGO_01612 1.81e-228 fhuB - - U ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MEFDBDGO_01613 8.17e-220 fhuG - - U ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MEFDBDGO_01614 3.74e-120 - - - K - - - Bacterial regulatory proteins, tetR family
MEFDBDGO_01615 6.73e-211 - - - GM - - - NmrA-like family
MEFDBDGO_01616 2.47e-168 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
MEFDBDGO_01617 1.4e-96 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
MEFDBDGO_01618 6.38e-195 - - - IQ - - - Enoyl-(Acyl carrier protein) reductase
MEFDBDGO_01619 3.86e-85 - - - K - - - helix_turn_helix, mercury resistance
MEFDBDGO_01620 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
MEFDBDGO_01621 2.22e-235 - - - S - - - Bacterial protein of unknown function (DUF916)
MEFDBDGO_01622 1.1e-115 - - - S - - - WxL domain surface cell wall-binding
MEFDBDGO_01623 1.23e-268 - - - NU - - - Mycoplasma protein of unknown function, DUF285
MEFDBDGO_01624 2.4e-152 - - - K - - - Bacterial regulatory proteins, tetR family
MEFDBDGO_01625 0.0 lepA2 - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MEFDBDGO_01626 0.0 nhaP4 - - P ko:K03316 - ko00000 Sodium proton antiporter
MEFDBDGO_01627 4.54e-202 - 3.6.1.22 - L ko:K03426 ko00760,ko01100,ko04146,map00760,map01100,map04146 ko00000,ko00001,ko01000 NADH pyrophosphatase zinc ribbon domain
MEFDBDGO_01628 1.29e-206 - - - K - - - LysR substrate binding domain
MEFDBDGO_01629 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
MEFDBDGO_01630 0.0 - - - S - - - MucBP domain
MEFDBDGO_01632 9.82e-111 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
MEFDBDGO_01633 1.9e-148 - - - K ko:K03489 - ko00000,ko03000 UTRA
MEFDBDGO_01634 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MEFDBDGO_01635 0.0 celD - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MEFDBDGO_01636 2.09e-85 - - - - - - - -
MEFDBDGO_01637 5.15e-16 - - - - - - - -
MEFDBDGO_01638 5.61e-54 pcaC 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
MEFDBDGO_01639 4.83e-31 - - - K - - - helix_turn_helix, mercury resistance
MEFDBDGO_01640 5.98e-85 - - - S - - - Protein of unknown function (DUF1093)
MEFDBDGO_01641 8.12e-282 - - - S - - - Membrane
MEFDBDGO_01642 2.97e-59 - - - S - - - Protein of unknown function (DUF3781)
MEFDBDGO_01643 5.35e-139 yoaZ - - S - - - intracellular protease amidase
MEFDBDGO_01644 1.35e-55 - - - K - - - HxlR-like helix-turn-helix
MEFDBDGO_01645 9.66e-77 - - - - - - - -
MEFDBDGO_01646 2.06e-81 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
MEFDBDGO_01647 5.31e-66 - - - K - - - Helix-turn-helix domain
MEFDBDGO_01648 9.09e-260 - - - C - - - Belongs to the LDH2 MDH2 oxidoreductase family
MEFDBDGO_01649 5.68e-155 yciB - - M - - - ErfK YbiS YcfS YnhG
MEFDBDGO_01650 6.62e-141 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
MEFDBDGO_01651 1.93e-139 - - - GM - - - NAD(P)H-binding
MEFDBDGO_01652 5.35e-102 - - - GM - - - SnoaL-like domain
MEFDBDGO_01653 0.0 qacA - - EGP - - - Fungal trichothecene efflux pump (TRI12)
MEFDBDGO_01654 2.52e-85 - - - S - - - Domain of unknown function (DUF4440)
MEFDBDGO_01655 6.49e-135 - - - K - - - Bacterial regulatory proteins, tetR family
MEFDBDGO_01656 5.39e-25 - - - L - - - HTH-like domain
MEFDBDGO_01657 1.06e-39 - - - L - - - Integrase core domain
MEFDBDGO_01658 9.58e-06 - - - L ko:K07483 - ko00000 transposase activity
MEFDBDGO_01659 8.53e-45 - - - L ko:K07483 - ko00000 transposase activity
MEFDBDGO_01661 6.79e-53 - - - - - - - -
MEFDBDGO_01662 5.06e-168 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MEFDBDGO_01663 9.26e-233 ydbI - - K - - - AI-2E family transporter
MEFDBDGO_01664 7.62e-270 xylR - - GK - - - ROK family
MEFDBDGO_01665 4.93e-149 - - - - - - - -
MEFDBDGO_01666 3.66e-295 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
MEFDBDGO_01667 1.41e-211 - - - - - - - -
MEFDBDGO_01668 1.66e-259 pkn2 - - KLT - - - Protein tyrosine kinase
MEFDBDGO_01669 5.03e-37 - - - S - - - Protein of unknown function (DUF4064)
MEFDBDGO_01670 2.47e-125 - - - S - - - Domain of unknown function (DUF4352)
MEFDBDGO_01671 9.69e-99 - - - S - - - Psort location Cytoplasmic, score
MEFDBDGO_01672 2.12e-72 - - - - - - - -
MEFDBDGO_01673 1.18e-141 - - - S ko:K07090 - ko00000 membrane transporter protein
MEFDBDGO_01674 5.93e-73 - - - S - - - branched-chain amino acid
MEFDBDGO_01675 2.05e-167 - - - E - - - branched-chain amino acid
MEFDBDGO_01676 1.66e-116 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
MEFDBDGO_01677 5.36e-305 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
MEFDBDGO_01678 5.61e-273 hpk31 - - T - - - Histidine kinase
MEFDBDGO_01679 1.14e-159 vanR - - K - - - response regulator
MEFDBDGO_01680 2.4e-161 - - - S - - - Protein of unknown function (DUF1275)
MEFDBDGO_01681 3.84e-207 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MEFDBDGO_01682 3.49e-270 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MEFDBDGO_01683 3.49e-160 - - - S - - - Protein of unknown function (DUF1129)
MEFDBDGO_01684 6.6e-255 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MEFDBDGO_01685 1.4e-40 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
MEFDBDGO_01686 3.98e-200 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
MEFDBDGO_01687 1.01e-175 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
MEFDBDGO_01688 7.39e-192 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
MEFDBDGO_01689 3.66e-168 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
MEFDBDGO_01690 1.66e-288 nupG - - F ko:K16323 - ko00000,ko02000 Nucleoside
MEFDBDGO_01691 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
MEFDBDGO_01692 5.43e-191 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
MEFDBDGO_01693 3.36e-216 - - - K - - - LysR substrate binding domain
MEFDBDGO_01694 5.69e-300 - - - EK - - - Aminotransferase, class I
MEFDBDGO_01695 1.11e-169 fliY - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
MEFDBDGO_01696 2.11e-158 tcyB - - E ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MEFDBDGO_01697 3.02e-176 - - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MEFDBDGO_01698 1.26e-161 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
MEFDBDGO_01699 8.83e-127 - - - KT - - - response to antibiotic
MEFDBDGO_01700 8.52e-70 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator
MEFDBDGO_01701 6.03e-133 - - - S - - - Protein of unknown function (DUF1700)
MEFDBDGO_01702 9.68e-202 - - - S - - - Putative adhesin
MEFDBDGO_01703 0.0 pts26BCA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MEFDBDGO_01704 0.0 malL 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
MEFDBDGO_01705 9.11e-233 purR2 - - K ko:K02529 - ko00000,ko03000 Periplasmic binding proteins and sugar binding domain of LacI family
MEFDBDGO_01706 4.35e-262 - - - S - - - DUF218 domain
MEFDBDGO_01707 9.95e-165 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
MEFDBDGO_01708 1.76e-152 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MEFDBDGO_01709 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MEFDBDGO_01710 6.26e-101 - - - - - - - -
MEFDBDGO_01711 5.43e-194 qorB 1.6.5.2 - GM ko:K19267 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NmrA-like family
MEFDBDGO_01712 8.33e-189 - - - S - - - haloacid dehalogenase-like hydrolase
MEFDBDGO_01713 1.29e-115 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
MEFDBDGO_01714 0.0 mngB 3.2.1.170 GH38 G ko:K15524 - ko00000,ko01000 Glycosyl hydrolases family 38 N-terminal domain
MEFDBDGO_01715 6.69e-155 fptC - - U ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 Phosphotransferase system, EIIC
MEFDBDGO_01716 2.52e-35 - 2.7.1.202 - G ko:K02769 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
MEFDBDGO_01717 5.55e-22 - - - G ko:K11203 - ko00000,ko00002,ko02000 PTS system, fructose subfamily
MEFDBDGO_01718 4.87e-102 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MEFDBDGO_01719 4.08e-101 - - - K - - - MerR family regulatory protein
MEFDBDGO_01720 8.79e-199 - - - GM - - - NmrA-like family
MEFDBDGO_01721 0.0 pts28ABC - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MEFDBDGO_01722 2.68e-143 nth2 - - L ko:K07457 - ko00000 Base excision DNA repair protein, HhH-GPD family
MEFDBDGO_01724 8.66e-130 - - - S - - - NADPH-dependent FMN reductase
MEFDBDGO_01725 3.43e-303 - - - S - - - module of peptide synthetase
MEFDBDGO_01726 4.71e-135 - - - - - - - -
MEFDBDGO_01727 1.55e-114 perR - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
MEFDBDGO_01728 7.43e-77 - - - S - - - Enterocin A Immunity
MEFDBDGO_01729 6.46e-49 - - - S - - - Phospholipase_D-nuclease N-terminal
MEFDBDGO_01730 7.93e-217 - 3.1.4.17, 3.1.4.53 - S ko:K01120,ko:K03651 ko00230,ko02025,map00230,map02025 ko00000,ko00001,ko01000 Calcineurin-like phosphoesterase
MEFDBDGO_01731 2.8e-135 - - - J - - - Acetyltransferase (GNAT) domain
MEFDBDGO_01732 9.76e-83 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 LrgA family
MEFDBDGO_01733 2.88e-164 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 LrgB-like family
MEFDBDGO_01734 1.9e-186 WQ51_01275 - - S - - - EDD domain protein, DegV family
MEFDBDGO_01735 1.03e-34 - - - - - - - -
MEFDBDGO_01736 4.23e-152 yugP - - S ko:K06973 - ko00000 Putative neutral zinc metallopeptidase
MEFDBDGO_01737 0.0 - 1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31 - Q ko:K10027 ko00906,ko01100,ko01110,map00906,map01100,map01110 ko00000,ko00001,ko01000 Flavin containing amine oxidoreductase
MEFDBDGO_01738 4.22e-212 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Squalene/phytoene synthase
MEFDBDGO_01739 4.68e-235 - - - D ko:K06889 - ko00000 Alpha beta
MEFDBDGO_01740 5.81e-251 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
MEFDBDGO_01741 0.0 gshR3 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
MEFDBDGO_01742 2.49e-73 - - - S - - - Enterocin A Immunity
MEFDBDGO_01743 7.41e-315 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MEFDBDGO_01744 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MEFDBDGO_01745 7.21e-236 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MEFDBDGO_01746 1.45e-187 ptp2 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
MEFDBDGO_01747 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MEFDBDGO_01749 1.88e-106 - - - - - - - -
MEFDBDGO_01750 0.0 yhdG - - E ko:K03294 - ko00000 C-terminus of AA_permease
MEFDBDGO_01752 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
MEFDBDGO_01753 1.07e-211 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MEFDBDGO_01754 1.54e-228 ydbI - - K - - - AI-2E family transporter
MEFDBDGO_01755 1.01e-277 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
MEFDBDGO_01756 1.15e-77 - - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
MEFDBDGO_01757 1.97e-60 qacH - - U ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
MEFDBDGO_01758 2.94e-149 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
MEFDBDGO_01759 7.27e-73 - - - K ko:K21903 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
MEFDBDGO_01760 1.3e-207 czcD - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
MEFDBDGO_01761 3.28e-133 - - - K - - - Helix-turn-helix XRE-family like proteins
MEFDBDGO_01763 2.77e-30 - - - - - - - -
MEFDBDGO_01765 3.91e-124 tag2 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
MEFDBDGO_01766 4.79e-272 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 dihydropteroate synthase
MEFDBDGO_01767 4.4e-138 folQ 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Ham1 family
MEFDBDGO_01768 0.0 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
MEFDBDGO_01769 1.8e-134 folE 2.7.6.3, 3.5.4.16 - F ko:K00950,ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase 1
MEFDBDGO_01770 1.59e-121 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
MEFDBDGO_01771 9.61e-84 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MEFDBDGO_01772 4.26e-109 cvpA - - S - - - Colicin V production protein
MEFDBDGO_01773 5.61e-216 - - - P ko:K02077 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
MEFDBDGO_01774 4.41e-316 - - - EGP - - - Major Facilitator
MEFDBDGO_01776 4.54e-54 - - - - - - - -
MEFDBDGO_01777 1.35e-55 - - - S - - - COG NOG38524 non supervised orthologous group
MEFDBDGO_01778 2.16e-124 - - - V - - - VanZ like family
MEFDBDGO_01779 1.87e-249 - - - V - - - Beta-lactamase
MEFDBDGO_01780 0.0 pflB 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 Pyruvate formate lyase-like
MEFDBDGO_01781 2.26e-206 pflA 1.97.1.4 - C ko:K04069 - ko00000,ko01000 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MEFDBDGO_01782 8.93e-71 - - - S - - - Pfam:DUF59
MEFDBDGO_01783 4.15e-183 ydhF - - S - - - Aldo keto reductase
MEFDBDGO_01784 2.42e-127 - - - FG - - - HIT domain
MEFDBDGO_01785 5.09e-51 - - - S - - - Bacteriocin-protection, YdeI or OmpD-Associated
MEFDBDGO_01786 4.29e-101 - - - - - - - -
MEFDBDGO_01787 1.3e-157 - - - E - - - GDSL-like Lipase/Acylhydrolase family
MEFDBDGO_01788 0.0 - - - U ko:K03451 - ko00000 Belongs to the BCCT transporter (TC 2.A.15) family
MEFDBDGO_01789 0.0 cadA - - P - - - P-type ATPase
MEFDBDGO_01791 8.09e-161 - - - S - - - YjbR
MEFDBDGO_01792 3.98e-169 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
MEFDBDGO_01793 7.42e-202 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
MEFDBDGO_01794 4.75e-267 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MEFDBDGO_01795 1.63e-281 pbpX - - V - - - Beta-lactamase
MEFDBDGO_01796 0.0 gdhA 1.4.1.4 - E ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
MEFDBDGO_01797 2.9e-139 - - - - - - - -
MEFDBDGO_01798 7.62e-97 - - - - - - - -
MEFDBDGO_01800 1.93e-210 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
MEFDBDGO_01801 5.73e-316 pts14C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MEFDBDGO_01802 3.93e-99 - - - T - - - Universal stress protein family
MEFDBDGO_01804 5.62e-316 yfmL - - L - - - DEAD DEAH box helicase
MEFDBDGO_01805 7.89e-245 mocA - - S - - - Oxidoreductase
MEFDBDGO_01806 6.22e-43 cspP - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
MEFDBDGO_01807 7.34e-83 - - - S - - - Domain of unknown function (DUF4828)
MEFDBDGO_01808 7.76e-186 lys - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
MEFDBDGO_01809 5.63e-196 gntR - - K - - - rpiR family
MEFDBDGO_01810 2.87e-215 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
MEFDBDGO_01811 7.06e-307 pts13C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MEFDBDGO_01812 0.0 yfgQ - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
MEFDBDGO_01813 5.56e-130 yobS - - K - - - Bacterial regulatory proteins, tetR family
MEFDBDGO_01814 0.0 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MEFDBDGO_01815 1.59e-242 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
MEFDBDGO_01816 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MEFDBDGO_01817 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MEFDBDGO_01818 5.11e-67 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MEFDBDGO_01819 9.48e-263 camS - - S - - - sex pheromone
MEFDBDGO_01820 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MEFDBDGO_01821 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
MEFDBDGO_01822 1.39e-279 purK2 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MEFDBDGO_01823 1.13e-120 yebE - - S - - - UPF0316 protein
MEFDBDGO_01824 2.01e-134 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MEFDBDGO_01825 9.78e-146 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
MEFDBDGO_01826 3.86e-235 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
MEFDBDGO_01827 8.5e-213 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
MEFDBDGO_01828 2.11e-233 hepT 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
MEFDBDGO_01829 2.2e-207 - - - S - - - L,D-transpeptidase catalytic domain
MEFDBDGO_01830 0.0 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
MEFDBDGO_01831 0.0 cydC - - CO ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
MEFDBDGO_01832 7.76e-234 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase subunit II
MEFDBDGO_01833 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
MEFDBDGO_01834 0.0 - - - S ko:K06889 - ko00000 Alpha beta
MEFDBDGO_01835 2.56e-34 - - - - - - - -
MEFDBDGO_01836 4.37e-128 - - - S - - - ECF transporter, substrate-specific component
MEFDBDGO_01837 0.0 - - - E ko:K03294 - ko00000 Amino Acid
MEFDBDGO_01838 2.6e-212 mleP2 - - S ko:K07088 - ko00000 Sodium Bile acid symporter family
MEFDBDGO_01839 0.0 mleS 1.1.1.38, 4.1.1.101 - C ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme
MEFDBDGO_01840 6.5e-215 mleR - - K - - - LysR family
MEFDBDGO_01841 2.62e-206 mleR2 - - K - - - LysR family transcriptional regulator
MEFDBDGO_01842 1.98e-122 citX 2.7.7.61 - HI ko:K05964 ko02020,map02020 ko00000,ko00001,ko01000 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
MEFDBDGO_01843 0.0 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
MEFDBDGO_01844 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MEFDBDGO_01845 2.05e-231 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
MEFDBDGO_01846 1.38e-19 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
MEFDBDGO_01849 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
MEFDBDGO_01850 1.5e-194 - - - S - - - Calcineurin-like phosphoesterase
MEFDBDGO_01854 5.78e-37 - - - S - - - Cupin 2, conserved barrel domain protein
MEFDBDGO_01855 1.38e-71 - - - S - - - Cupin domain
MEFDBDGO_01856 3.62e-211 pphA 3.1.3.16 - T ko:K07313 - ko00000,ko01000 Calcineurin-like phosphoesterase
MEFDBDGO_01857 1.59e-247 ysdE - - P - - - Citrate transporter
MEFDBDGO_01858 1.06e-195 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
MEFDBDGO_01859 5.35e-175 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MEFDBDGO_01860 8.37e-280 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
MEFDBDGO_01861 5.41e-160 yvoA_2 - - K ko:K03710 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
MEFDBDGO_01862 2.31e-176 tagA 2.4.1.187 GT26 F ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
MEFDBDGO_01863 0.0 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MEFDBDGO_01864 5.27e-197 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MEFDBDGO_01865 0.0 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
MEFDBDGO_01866 6.3e-95 - - - - ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 -
MEFDBDGO_01867 0.0 tex - - K ko:K06959 - ko00000 Tex-like protein N-terminal domain protein
MEFDBDGO_01868 7.89e-109 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
MEFDBDGO_01869 1.71e-302 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
MEFDBDGO_01870 8.77e-204 thrB 2.7.1.39 - F ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MEFDBDGO_01872 1e-200 - - - G - - - Peptidase_C39 like family
MEFDBDGO_01873 6.46e-218 manL 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
MEFDBDGO_01874 4.51e-172 manM - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system
MEFDBDGO_01875 1.87e-219 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
MEFDBDGO_01876 9.05e-85 manO - - S - - - Domain of unknown function (DUF956)
MEFDBDGO_01877 0.0 levR - - K - - - Sigma-54 interaction domain
MEFDBDGO_01878 1.19e-92 levD 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11194 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
MEFDBDGO_01879 4.5e-113 manX 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
MEFDBDGO_01880 3.02e-227 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MEFDBDGO_01881 9.24e-85 accB1 - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin-requiring enzyme
MEFDBDGO_01882 1.7e-315 accC1 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase C-terminal domain
MEFDBDGO_01883 1.49e-183 accD1 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MEFDBDGO_01884 1.23e-177 accA1 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
MEFDBDGO_01885 2.29e-234 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
MEFDBDGO_01886 7.53e-215 mleP2 - - S ko:K07088 - ko00000 Transporter, auxin efflux carrier (AEC) family protein
MEFDBDGO_01887 6.04e-227 - - - EG - - - EamA-like transporter family
MEFDBDGO_01888 3.3e-166 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MEFDBDGO_01889 1.12e-147 zmp2 - - O - - - Zinc-dependent metalloprotease
MEFDBDGO_01890 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
MEFDBDGO_01891 1.62e-158 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MEFDBDGO_01892 5.96e-69 yjdJ - - S ko:K06975 - ko00000 GCN5-related N-acetyl-transferase
MEFDBDGO_01893 3.29e-127 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
MEFDBDGO_01894 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MEFDBDGO_01895 4.91e-265 yacL - - S - - - domain protein
MEFDBDGO_01896 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MEFDBDGO_01897 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
MEFDBDGO_01898 1.35e-92 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MEFDBDGO_01899 1.49e-177 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MEFDBDGO_01900 5.87e-127 yacP - - S ko:K06962 - ko00000 YacP-like NYN domain
MEFDBDGO_01901 1.12e-130 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Sigma-70 region 2
MEFDBDGO_01902 4.55e-31 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
MEFDBDGO_01903 1e-39 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MEFDBDGO_01904 1.89e-128 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
MEFDBDGO_01905 2.81e-202 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
MEFDBDGO_01906 9.76e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MEFDBDGO_01907 7.7e-158 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MEFDBDGO_01908 3.72e-105 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MEFDBDGO_01909 2.76e-74 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MEFDBDGO_01910 9.53e-285 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
MEFDBDGO_01911 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MEFDBDGO_01912 7.12e-256 glmS2 - - M - - - SIS domain
MEFDBDGO_01913 3.58e-36 - - - S - - - Belongs to the LOG family
MEFDBDGO_01914 0.0 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
MEFDBDGO_01915 0.0 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
MEFDBDGO_01916 2.65e-215 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
MEFDBDGO_01917 1.65e-112 pgpA - - I - - - Phosphatidylglycerophosphatase A
MEFDBDGO_01918 5.54e-209 - - - GM - - - NmrA-like family
MEFDBDGO_01919 1.24e-85 - - - K ko:K22296 - ko00000,ko03000 Winged helix DNA-binding domain
MEFDBDGO_01920 9.97e-94 spxA - - P ko:K16509 - ko00000 ArsC family
MEFDBDGO_01921 3.46e-87 yeaO - - S - - - Protein of unknown function, DUF488
MEFDBDGO_01922 1.7e-70 - - - - - - - -
MEFDBDGO_01923 4.98e-275 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific adenine glycosylase
MEFDBDGO_01924 2.11e-82 - - - - - - - -
MEFDBDGO_01925 1.36e-112 - - - - - - - -
MEFDBDGO_01926 3.22e-103 hsp3 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
MEFDBDGO_01927 2.27e-74 - - - - - - - -
MEFDBDGO_01928 4.79e-21 - - - - - - - -
MEFDBDGO_01929 3.57e-150 - - - GM - - - NmrA-like family
MEFDBDGO_01930 2.52e-107 - - - S ko:K02348 - ko00000 GNAT family
MEFDBDGO_01931 1.63e-203 - - - EG - - - EamA-like transporter family
MEFDBDGO_01932 2.66e-155 - - - S - - - membrane
MEFDBDGO_01933 2.55e-145 - - - S - - - VIT family
MEFDBDGO_01934 1.78e-242 pva2 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
MEFDBDGO_01935 0.0 copB 3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54 - P ko:K01533,ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
MEFDBDGO_01936 4.83e-98 copR - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor CopY TcrY
MEFDBDGO_01937 4.26e-54 - - - - - - - -
MEFDBDGO_01938 5.93e-97 - - - S - - - COG NOG18757 non supervised orthologous group
MEFDBDGO_01939 8.8e-315 lmrB - - U ko:K18926 - ko00000,ko00002,ko02000 Belongs to the major facilitator superfamily
MEFDBDGO_01940 8.44e-34 - - - - - - - -
MEFDBDGO_01941 2.55e-65 - - - - - - - -
MEFDBDGO_01942 2.41e-84 - - - S - - - Protein of unknown function (DUF1398)
MEFDBDGO_01943 0.0 - - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
MEFDBDGO_01944 1.77e-282 mdtG - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
MEFDBDGO_01945 5.99e-231 ybcH - - D ko:K06889 - ko00000 Alpha beta
MEFDBDGO_01946 6.1e-101 - - - K - - - Domain of unknown function (DUF1836)
MEFDBDGO_01947 1.14e-110 - - - F - - - Nucleoside 2-deoxyribosyltransferase
MEFDBDGO_01948 0.0 pacL3 3.6.3.8 - P ko:K01537 - ko00000,ko01000 Cation transporter/ATPase, N-terminus
MEFDBDGO_01949 0.0 yfkN 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
MEFDBDGO_01950 2.8e-205 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
MEFDBDGO_01951 1.36e-209 yvgN - - C - - - Aldo keto reductase
MEFDBDGO_01952 2.57e-171 - - - S - - - Putative threonine/serine exporter
MEFDBDGO_01953 2.07e-102 - - - S - - - Threonine/Serine exporter, ThrE
MEFDBDGO_01954 1.05e-56 - - - S - - - Protein of unknown function (DUF1093)
MEFDBDGO_01955 2.69e-190 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MEFDBDGO_01956 5.94e-118 ymdB - - S - - - Macro domain protein
MEFDBDGO_01957 1.31e-123 - - - K ko:K22041 - ko00000,ko03000 transcriptional regulator
MEFDBDGO_01958 1.58e-66 - - - - - - - -
MEFDBDGO_01959 2.41e-212 - - - S - - - Protein of unknown function (DUF1002)
MEFDBDGO_01960 0.0 - - - - - - - -
MEFDBDGO_01961 1.36e-245 - - - S - - - Bacterial protein of unknown function (DUF916)
MEFDBDGO_01962 5.48e-171 - - - S - - - WxL domain surface cell wall-binding
MEFDBDGO_01963 1.63e-176 yesN - - T ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
MEFDBDGO_01964 5.33e-114 - - - K - - - Winged helix DNA-binding domain
MEFDBDGO_01965 3.81e-150 - - - K - - - Bacterial regulatory proteins, tetR family
MEFDBDGO_01966 0.0 pckA 4.1.1.49 - H ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Phosphoenolpyruvate carboxykinase
MEFDBDGO_01967 4.45e-38 - - - - - - - -
MEFDBDGO_01968 0.0 gadB 4.1.1.15, 4.1.2.27 - E ko:K01580,ko:K01634 ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940 ko00000,ko00001,ko00002,ko01000 Belongs to the group II decarboxylase family
MEFDBDGO_01969 1.65e-106 - - - M - - - PFAM NLP P60 protein
MEFDBDGO_01970 6.18e-71 - - - - - - - -
MEFDBDGO_01971 5.77e-81 - - - - - - - -
MEFDBDGO_01973 5.13e-138 - - - - - - - -
MEFDBDGO_01974 1.43e-67 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2316)
MEFDBDGO_01975 5.87e-207 - - - S ko:K07045 - ko00000 Amidohydrolase
MEFDBDGO_01976 1.37e-135 - - - K - - - transcriptional regulator
MEFDBDGO_01977 1.02e-231 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Peroxidase
MEFDBDGO_01978 4.16e-175 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
MEFDBDGO_01979 3.04e-165 - - - S - - - Gram-negative-bacterium-type cell wall biogenesis
MEFDBDGO_01980 2.93e-234 - - - E - - - GDSL-like Lipase/Acylhydrolase family
MEFDBDGO_01981 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 P-type ATPase
MEFDBDGO_01982 9.44e-183 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
MEFDBDGO_01983 5.73e-73 trxA3 - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Thioredoxin-like domain
MEFDBDGO_01984 4.82e-55 yrkD - - S - - - Metal-sensitive transcriptional repressor
MEFDBDGO_01985 1.01e-26 - - - - - - - -
MEFDBDGO_01986 4.27e-126 dpsB - - P - - - Belongs to the Dps family
MEFDBDGO_01987 2.98e-44 copZ - - P - - - Heavy-metal-associated domain
MEFDBDGO_01988 1.82e-152 rcfA - - K ko:K21562 - ko00000,ko03000 Transcriptional regulator, Crp Fnr family
MEFDBDGO_01989 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
MEFDBDGO_01990 5.23e-107 yoaA - - J - - - COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MEFDBDGO_01991 0.0 nox 1.6.3.4 - C ko:K17869 - ko00000,ko01000 NADH oxidase
MEFDBDGO_01992 0.0 - - - S - - - Leucine-rich repeat (LRR) protein
MEFDBDGO_01993 1.83e-235 - - - S - - - Cell surface protein
MEFDBDGO_01994 7.12e-159 - - - S - - - WxL domain surface cell wall-binding
MEFDBDGO_01995 4.23e-129 - - - S - - - WxL domain surface cell wall-binding
MEFDBDGO_01996 7.83e-60 - - - - - - - -
MEFDBDGO_01997 1.72e-135 yezE - - K ko:K16137 - ko00000,ko03000 Bacterial regulatory proteins, tetR family
MEFDBDGO_01998 1.03e-65 - - - - - - - -
MEFDBDGO_01999 9.34e-317 - - - S - - - Putative metallopeptidase domain
MEFDBDGO_02000 4.03e-283 - - - S - - - associated with various cellular activities
MEFDBDGO_02001 1.95e-140 aqpZ - - U ko:K06188 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
MEFDBDGO_02002 0.0 ubiB - - S ko:K03688 - ko00000 ABC1 family
MEFDBDGO_02003 0.0 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
MEFDBDGO_02004 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
MEFDBDGO_02005 0.0 lacA 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 -beta-galactosidase
MEFDBDGO_02006 4.73e-242 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
MEFDBDGO_02007 0.0 - 3.2.1.40 - G ko:K05989 - ko00000,ko01000 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
MEFDBDGO_02008 3.03e-295 - - - P ko:K06610 - ko00000,ko02000 Sugar (and other) transporter
MEFDBDGO_02009 0.0 ram2 3.2.1.40 - G ko:K05989 - ko00000,ko01000 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
MEFDBDGO_02010 5.06e-298 - - - P ko:K06610 - ko00000,ko02000 Major Facilitator Superfamily
MEFDBDGO_02011 1.29e-235 - - - K - - - helix_turn_helix, arabinose operon control protein
MEFDBDGO_02012 1.12e-142 fic - - D ko:K04095 - ko00000,ko03036 Fic/DOC family
MEFDBDGO_02013 3.4e-100 - - - K ko:K07726 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
MEFDBDGO_02014 1.19e-234 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
MEFDBDGO_02015 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
MEFDBDGO_02016 1.26e-245 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
MEFDBDGO_02017 1.65e-286 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MEFDBDGO_02018 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
MEFDBDGO_02019 6.68e-238 lacM 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase
MEFDBDGO_02020 0.0 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
MEFDBDGO_02021 0.0 lacP - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
MEFDBDGO_02022 1.43e-251 galM3 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
MEFDBDGO_02023 3.69e-232 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
MEFDBDGO_02024 5.16e-248 tas3 - - C ko:K19265 - ko00000,ko01000 Aldo keto reductase family protein
MEFDBDGO_02025 2.02e-85 - - - S - - - pyridoxamine 5-phosphate
MEFDBDGO_02026 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
MEFDBDGO_02027 1.23e-228 apbE3 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MEFDBDGO_02028 3.65e-172 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
MEFDBDGO_02029 3.21e-212 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MEFDBDGO_02030 1.66e-208 - - - K - - - Transcriptional regulator, LysR family
MEFDBDGO_02031 1.4e-282 - - - EGP - - - Major Facilitator Superfamily
MEFDBDGO_02032 2.83e-206 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MEFDBDGO_02033 3.31e-205 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MEFDBDGO_02034 1.64e-202 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
MEFDBDGO_02035 5.56e-212 - - - G - - - Xylose isomerase-like TIM barrel
MEFDBDGO_02036 1.73e-215 - - - K - - - Transcriptional regulator, LysR family
MEFDBDGO_02037 1.12e-262 - - - EGP - - - Major Facilitator Superfamily
MEFDBDGO_02038 2.09e-83 - - - - - - - -
MEFDBDGO_02039 2.63e-200 estA - - S - - - Putative esterase
MEFDBDGO_02040 9.03e-173 - - - K - - - UTRA domain
MEFDBDGO_02041 0.0 pts29C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MEFDBDGO_02042 3.06e-212 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MEFDBDGO_02043 1.58e-207 - - - G - - - BadF/BadG/BcrA/BcrD ATPase family
MEFDBDGO_02044 5.56e-270 - - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
MEFDBDGO_02045 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MEFDBDGO_02046 0.0 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MEFDBDGO_02047 3.72e-200 bglG4 - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
MEFDBDGO_02048 0.0 pbg9 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MEFDBDGO_02049 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MEFDBDGO_02050 0.0 pts33BCA - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MEFDBDGO_02051 1.3e-203 bglG5 - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
MEFDBDGO_02052 0.0 treP 2.4.1.64 GH65 G ko:K05342 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
MEFDBDGO_02053 2.66e-222 cytR - - K ko:K02529,ko:K03604 - ko00000,ko03000 Transcriptional regulator, LacI family
MEFDBDGO_02054 0.0 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
MEFDBDGO_02055 0.0 agl 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 31 family
MEFDBDGO_02057 1.15e-236 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MEFDBDGO_02058 3.44e-135 yxeH - - S - - - hydrolase
MEFDBDGO_02059 0.0 tkt 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MEFDBDGO_02060 8.34e-147 tal 2.2.1.2 - F ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MEFDBDGO_02061 1.43e-306 ulaA - - S ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
MEFDBDGO_02062 2.97e-60 ulaB 2.7.1.194 - G ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase system galactitol-specific IIB component
MEFDBDGO_02063 1.58e-101 - 2.7.1.194 - G ko:K02821 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MEFDBDGO_02064 0.0 - - - G ko:K03483 - ko00000,ko03000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MEFDBDGO_02065 4.53e-146 gph3 - - S - - - Haloacid dehalogenase-like hydrolase
MEFDBDGO_02066 5.26e-247 - 1.1.1.14 - C ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Zinc-binding dehydrogenase
MEFDBDGO_02067 8.37e-296 gatC - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
MEFDBDGO_02068 6e-60 - 2.7.1.200 - G ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
MEFDBDGO_02069 1.1e-103 - 2.7.1.200, 2.7.1.204 - G ko:K02773,ko:K20112 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MEFDBDGO_02070 3.05e-161 - - - K ko:K02444 - ko00000,ko03000 DeoR C terminal sensor domain
MEFDBDGO_02071 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
MEFDBDGO_02072 1.09e-66 yueI - - S - - - Protein of unknown function (DUF1694)
MEFDBDGO_02073 4.84e-14 yueI - - S - - - Protein of unknown function (DUF1694)
MEFDBDGO_02074 6.83e-133 maa 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
MEFDBDGO_02075 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
MEFDBDGO_02076 1.06e-175 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
MEFDBDGO_02077 0.0 araB 2.7.1.16 - G ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 carbohydrate kinase FGGY
MEFDBDGO_02078 0.0 araP - - U - - - Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MEFDBDGO_02079 1.2e-262 araR - - K ko:K02103 - ko00000,ko03000 Transcriptional regulator
MEFDBDGO_02080 3.76e-180 - - - K - - - Helix-turn-helix domain, rpiR family
MEFDBDGO_02081 6.47e-95 - - - S - - - Protein of unknown function (DUF1694)
MEFDBDGO_02082 2.54e-210 - - - I - - - alpha/beta hydrolase fold
MEFDBDGO_02083 1.65e-206 - - - I - - - alpha/beta hydrolase fold
MEFDBDGO_02084 0.0 - - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MEFDBDGO_02085 4.01e-263 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MEFDBDGO_02086 3.83e-174 - - - G - - - Xylose isomerase domain protein TIM barrel
MEFDBDGO_02087 2.93e-200 nanK - - GK - - - ROK family
MEFDBDGO_02088 1.86e-210 nanA 4.1.3.3 - EM ko:K01639 ko00520,map00520 ko00000,ko00001,ko01000 Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
MEFDBDGO_02089 3.53e-158 nanE 5.1.3.9 - G ko:K01788 ko00520,map00520 ko00000,ko00001,ko01000 Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
MEFDBDGO_02090 2.28e-291 - - - S - - - Pyridine nucleotide-disulphide oxidoreductase
MEFDBDGO_02091 2.43e-91 - - - S - - - Pyrimidine dimer DNA glycosylase
MEFDBDGO_02092 1.22e-115 - - - T - - - ECF transporter, substrate-specific component
MEFDBDGO_02093 1.06e-16 - - - - - - - -
MEFDBDGO_02094 1.96e-21 ytgB - - S - - - Transglycosylase associated protein
MEFDBDGO_02095 0.0 katA 1.11.1.6 - C ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 Belongs to the catalase family
MEFDBDGO_02096 5.38e-101 nrp - - K ko:K16509 - ko00000 ArsC family
MEFDBDGO_02097 4.29e-173 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
MEFDBDGO_02098 3.78e-212 blpH 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
MEFDBDGO_02099 9.62e-19 - - - - - - - -
MEFDBDGO_02100 5.01e-84 - - - KOT ko:K07813 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01002 May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor
MEFDBDGO_02101 0.0 clpL - - O ko:K04086 - ko00000,ko03110 C-terminal, D2-small domain, of ClpB protein
MEFDBDGO_02103 1.97e-256 lctO 1.13.12.4 - C ko:K00467,ko:K10530 ko00620,map00620 ko00000,ko00001,ko01000 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
MEFDBDGO_02104 0.0 pox4 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
MEFDBDGO_02105 5.03e-95 - - - K - - - Transcriptional regulator
MEFDBDGO_02106 0.0 spxB 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
MEFDBDGO_02107 4.04e-94 yueI - - S - - - Protein of unknown function (DUF1694)
MEFDBDGO_02108 1.45e-162 - - - S - - - Membrane
MEFDBDGO_02109 1.31e-210 rhaD 4.1.2.19 - H ko:K01629 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
MEFDBDGO_02110 0.0 rhaA 2.7.1.5, 5.3.1.14 - G ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 L-rhamnose isomerase (RhaA)
MEFDBDGO_02111 4.22e-74 rhaM 5.1.3.32 - G ko:K03534 - ko00000,ko01000 Involved in the anomeric conversion of L-rhamnose
MEFDBDGO_02112 0.0 rhaB 2.7.1.5 - F ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
MEFDBDGO_02113 7.74e-313 iolF - - P ko:K06610 - ko00000,ko02000 Sugar (and other) transporter
MEFDBDGO_02114 8.35e-230 rhaR - - K - - - helix_turn_helix, arabinose operon control protein
MEFDBDGO_02115 1.28e-180 - - - K - - - DeoR C terminal sensor domain
MEFDBDGO_02116 9.79e-151 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
MEFDBDGO_02117 4.02e-272 - - - L ko:K07487 - ko00000 Transposase
MEFDBDGO_02118 3.69e-112 - - - L ko:K07487 - ko00000 Transposase
MEFDBDGO_02120 1.08e-208 - - - - - - - -
MEFDBDGO_02121 2.76e-28 - - - S - - - Cell surface protein
MEFDBDGO_02124 2.03e-12 - - - L - - - Helix-turn-helix domain
MEFDBDGO_02125 4.32e-16 - - - L - - - Helix-turn-helix domain
MEFDBDGO_02126 2.28e-22 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
MEFDBDGO_02127 2.15e-17 - - - M - - - Domain of unknown function (DUF5011)
MEFDBDGO_02128 3.07e-06 - - - D - - - Mycoplasma protein of unknown function, DUF285
MEFDBDGO_02130 1.56e-69 - - - K - - - helix_turn_helix, arabinose operon control protein
MEFDBDGO_02131 3.08e-17 - - - L ko:K07487 - ko00000 Transposase
MEFDBDGO_02133 2.12e-27 - - - L ko:K07487 - ko00000 Transposase
MEFDBDGO_02134 9.07e-22 - - - L ko:K07487 - ko00000 Transposase
MEFDBDGO_02135 1.1e-184 - - - M - - - Domain of unknown function (DUF5011)
MEFDBDGO_02136 8.16e-95 - - - M - - - Glycosyl hydrolases family 25
MEFDBDGO_02137 5.42e-18 - - - S - - - L,D-transpeptidase catalytic domain
MEFDBDGO_02138 3.95e-92 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Belongs to the DNA polymerase type-Y family
MEFDBDGO_02139 0.0 bgl 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MEFDBDGO_02140 4.02e-205 ypbG 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
MEFDBDGO_02141 0.0 - 2.3.1.204, 3.2.1.170, 3.2.1.24 GH38 G ko:K01191,ko:K15524,ko:K16869 ko00511,map00511 ko00000,ko00001,ko01000,ko04131 Glycosyl hydrolases family 38 N-terminal domain
MEFDBDGO_02142 0.0 - - - S ko:K09704 - ko00000 Metal-independent alpha-mannosidase (GH125)
MEFDBDGO_02143 2.66e-248 - - - K - - - Transcriptional regulator
MEFDBDGO_02144 0.0 ypdD - - G - - - Glycosyl hydrolase family 92
MEFDBDGO_02145 1.81e-274 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MEFDBDGO_02146 3.76e-212 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
MEFDBDGO_02147 0.0 - - - K ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, arabinose operon control protein
MEFDBDGO_02148 0.0 - 2.7.13.3 - T ko:K07718 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MEFDBDGO_02149 1.71e-139 ypcB - - S - - - integral membrane protein
MEFDBDGO_02150 0.0 dexB 3.2.1.70 - G ko:K01215 - ko00000,ko01000 Alpha amylase, catalytic domain protein
MEFDBDGO_02151 0.0 ypcG - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Domain of unknown function (DUF3502)
MEFDBDGO_02152 6.47e-213 lplC - - U ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MEFDBDGO_02153 1.29e-231 ypdA - - U ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MEFDBDGO_02154 0.0 - 3.2.1.52 GH20 G ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko03110 Glycosyl hydrolase family 20, catalytic domain
MEFDBDGO_02155 9.5e-200 - - - K - - - helix_turn_helix, arabinose operon control protein
MEFDBDGO_02156 0.0 mdlA2 - - V ko:K06147 - ko00000,ko02000 ABC transporter
MEFDBDGO_02157 0.0 yknV - - V ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MEFDBDGO_02158 1.48e-247 - - - K - - - helix_turn_helix gluconate operon transcriptional repressor
MEFDBDGO_02159 1.91e-201 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
MEFDBDGO_02160 6.96e-83 pts38A 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
MEFDBDGO_02161 2.5e-234 srlE 2.7.1.198 - G ko:K02782,ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Sorbitol phosphotransferase enzyme II N-terminus
MEFDBDGO_02162 1.23e-129 srlA - - G ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko02000 PTS system enzyme II sorbitol-specific factor
MEFDBDGO_02163 3.33e-113 srlM1 - - K - - - Glucitol operon activator protein (GutM)
MEFDBDGO_02164 0.0 srlM - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
MEFDBDGO_02165 2.21e-185 srlD2 1.1.1.140 - IQ ko:K00068 ko00051,map00051 ko00000,ko00001,ko01000 NAD dependent epimerase/dehydratase family
MEFDBDGO_02166 2.53e-209 rbsU - - U ko:K06216 - ko00000,ko02000 ribose uptake protein RbsU
MEFDBDGO_02167 4.99e-88 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
MEFDBDGO_02168 7.82e-210 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MEFDBDGO_02169 4.04e-241 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
MEFDBDGO_02170 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
MEFDBDGO_02171 2.51e-103 - - - T - - - Universal stress protein family
MEFDBDGO_02172 7.43e-130 padR - - K - - - Virulence activator alpha C-term
MEFDBDGO_02173 2.71e-135 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
MEFDBDGO_02174 1.44e-185 mhpD - - Q ko:K02509 ko00350,ko01120,map00350,map01120 ko00000,ko00001,ko01000 hydratase
MEFDBDGO_02175 3.66e-113 - - - K - - - Acetyltransferase (GNAT) domain
MEFDBDGO_02176 3.3e-202 degV1 - - S - - - DegV family
MEFDBDGO_02177 1.67e-79 - - - K - - - Bacteriophage CI repressor helix-turn-helix domain
MEFDBDGO_02178 0.0 pepE 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
MEFDBDGO_02180 2.76e-141 sip3 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
MEFDBDGO_02181 0.0 - - - - - - - -
MEFDBDGO_02183 2.23e-211 - - - S - - - Bacterial protein of unknown function (DUF916)
MEFDBDGO_02184 1.31e-143 - - - S - - - Cell surface protein
MEFDBDGO_02185 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MEFDBDGO_02186 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MEFDBDGO_02187 2.37e-173 jag - - S ko:K06346 - ko00000 R3H domain protein
MEFDBDGO_02188 2.26e-306 - - - Q - - - Imidazolonepropionase and related amidohydrolases
MEFDBDGO_02189 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MEFDBDGO_02190 1.55e-158 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MEFDBDGO_02191 3.74e-75 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MEFDBDGO_02192 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MEFDBDGO_02193 8.19e-267 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MEFDBDGO_02194 3.82e-51 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain protein YaaA
MEFDBDGO_02195 7.24e-263 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MEFDBDGO_02196 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MEFDBDGO_02197 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MEFDBDGO_02198 5.95e-65 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
MEFDBDGO_02199 1.68e-108 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MEFDBDGO_02200 2.69e-47 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MEFDBDGO_02201 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
MEFDBDGO_02202 3.44e-95 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
MEFDBDGO_02203 8.77e-317 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
MEFDBDGO_02204 0.0 - - - L ko:K07487 - ko00000 Transposase
MEFDBDGO_02205 1.17e-287 yttB - - EGP - - - Major Facilitator
MEFDBDGO_02206 9e-184 proB 2.7.2.11 - F ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MEFDBDGO_02207 3.25e-292 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MEFDBDGO_02209 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MEFDBDGO_02211 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MEFDBDGO_02212 6.65e-282 glgC 2.7.7.27 - H ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MEFDBDGO_02213 3.49e-269 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
MEFDBDGO_02214 0.0 glgA 2.4.1.21 GT5 F ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
MEFDBDGO_02215 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
MEFDBDGO_02216 0.0 malZ 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31 G ko:K01187,ko:K01200 ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
MEFDBDGO_02218 8.38e-184 - - - S - - - haloacid dehalogenase-like hydrolase
MEFDBDGO_02219 1.1e-154 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
MEFDBDGO_02220 0.0 trePP 2.4.1.216, 2.4.1.8 GH65 G ko:K00691,ko:K03731 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycosyl hydrolase family 65 central catalytic domain
MEFDBDGO_02221 3.21e-104 - - - S - - - Pyridoxamine 5'-phosphate oxidase
MEFDBDGO_02222 4.37e-43 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock protein domain
MEFDBDGO_02223 2.54e-50 - - - - - - - -
MEFDBDGO_02225 1.56e-169 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
MEFDBDGO_02226 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MEFDBDGO_02227 3.55e-313 yycH - - S - - - YycH protein
MEFDBDGO_02228 3.54e-195 yycI - - S - - - YycH protein
MEFDBDGO_02229 1.71e-200 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
MEFDBDGO_02230 1.5e-253 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
MEFDBDGO_02231 2.48e-106 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MEFDBDGO_02232 2e-123 - - - K - - - Bacterial regulatory proteins, tetR family
MEFDBDGO_02233 0.0 - - - C - - - Belongs to the aldehyde dehydrogenase family
MEFDBDGO_02234 5.97e-157 ung2 - - L - - - Uracil-DNA glycosylase
MEFDBDGO_02235 2.24e-155 pnb - - C - - - nitroreductase
MEFDBDGO_02236 5.78e-85 - 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 6-pyruvoyl tetrahydropterin synthase
MEFDBDGO_02237 6.13e-148 - - - S - - - Elongation factor G-binding protein, N-terminal
MEFDBDGO_02238 0.0 - - - C - - - FMN_bind
MEFDBDGO_02239 0.0 - - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
MEFDBDGO_02240 3.43e-203 - - - K - - - LysR family
MEFDBDGO_02241 1.69e-93 - - - C - - - FMN binding
MEFDBDGO_02242 1.82e-97 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MEFDBDGO_02243 3.34e-210 - - - S - - - KR domain
MEFDBDGO_02244 9.51e-203 adc 4.1.1.4 - Q ko:K01574 ko00072,ko00640,ko01100,map00072,map00640,map01100 ko00000,ko00001,ko00002,ko01000 Acetoacetate decarboxylase (ADC)
MEFDBDGO_02245 5.07e-157 ydgI - - C - - - Nitroreductase family
MEFDBDGO_02246 0.0 - - - QT - - - PucR C-terminal helix-turn-helix domain
MEFDBDGO_02247 2.22e-154 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
MEFDBDGO_02248 2.28e-250 pva1 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MEFDBDGO_02249 0.0 - - - S - - - Putative threonine/serine exporter
MEFDBDGO_02250 6.86e-175 ptp1 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
MEFDBDGO_02251 0.0 hpaH 1.14.14.8, 1.14.14.9 - Q ko:K00483,ko:K16901 ko00350,ko00380,ko01120,ko01220,map00350,map00380,map01120,map01220 ko00000,ko00001,ko01000 4-hydroxyphenylacetate
MEFDBDGO_02252 1.65e-106 - - - S - - - ASCH
MEFDBDGO_02253 1.25e-164 - - - F - - - glutamine amidotransferase
MEFDBDGO_02254 1.88e-216 - - - K - - - WYL domain
MEFDBDGO_02255 6.65e-152 azoR - - C ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MEFDBDGO_02256 0.0 fusA1 - - J - - - elongation factor G
MEFDBDGO_02257 3.66e-59 - - - S - - - Protein of unknown function
MEFDBDGO_02258 2.84e-81 - - - S - - - Protein of unknown function
MEFDBDGO_02259 4.28e-195 - - - EG - - - EamA-like transporter family
MEFDBDGO_02260 7.65e-121 yfbM - - K - - - FR47-like protein
MEFDBDGO_02261 1.4e-162 - - - S - - - DJ-1/PfpI family
MEFDBDGO_02262 3.42e-234 - 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 nadph quinone reductase
MEFDBDGO_02263 1.92e-67 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
MEFDBDGO_02264 5.72e-300 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
MEFDBDGO_02265 3.5e-217 pepI 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
MEFDBDGO_02266 7.76e-181 XK27_08125 - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
MEFDBDGO_02267 2.38e-99 - - - - - - - -
MEFDBDGO_02268 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
MEFDBDGO_02269 5.9e-181 - - - - - - - -
MEFDBDGO_02270 4.07e-05 - - - - - - - -
MEFDBDGO_02271 2.92e-186 ant1 2.7.7.47 - H ko:K00984 - ko00000,ko01000,ko01504 Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
MEFDBDGO_02272 1.67e-54 - - - - - - - -
MEFDBDGO_02273 8.65e-166 - - - P ko:K02006 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MEFDBDGO_02274 8.38e-193 - - - P ko:K02008 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
MEFDBDGO_02275 1.06e-234 cbiM - - P ko:K02007 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PDGLE domain
MEFDBDGO_02276 1.39e-156 rcfB - - K - - - Crp-like helix-turn-helix domain
MEFDBDGO_02277 7.9e-306 larA 5.1.2.1 - S ko:K22373 ko00620,map00620 ko00000,ko00001,ko01000 Domain of unknown function (DUF2088)
MEFDBDGO_02278 2.65e-162 larB - - S ko:K06898 - ko00000 AIR carboxylase
MEFDBDGO_02279 2.03e-179 larC 4.99.1.12 - S ko:K09121 - ko00000,ko01000 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
MEFDBDGO_02280 6.32e-99 larC2 4.99.1.12 - S ko:K09121 - ko00000,ko01000 Protein of unknown function DUF111
MEFDBDGO_02281 1.19e-170 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
MEFDBDGO_02282 6.38e-194 larE - - S ko:K06864 - ko00000 NAD synthase
MEFDBDGO_02283 4.79e-225 - - - C - - - Zinc-binding dehydrogenase
MEFDBDGO_02284 2.27e-176 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MEFDBDGO_02285 9.72e-188 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
MEFDBDGO_02286 2.68e-143 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
MEFDBDGO_02287 9.14e-265 thiP - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
MEFDBDGO_02288 7.45e-178 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
MEFDBDGO_02289 0.0 - - - L - - - HIRAN domain
MEFDBDGO_02290 1.24e-109 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
MEFDBDGO_02291 0.0 yifK - - E ko:K03293 - ko00000 Amino acid permease
MEFDBDGO_02292 2.26e-153 - - - - - - - -
MEFDBDGO_02293 1.2e-190 - - - I - - - Alpha/beta hydrolase family
MEFDBDGO_02294 0.0 pacL1 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
MEFDBDGO_02295 1.29e-181 - - - F - - - Phosphorylase superfamily
MEFDBDGO_02296 0.0 - - - L ko:K07487 - ko00000 Transposase
MEFDBDGO_02297 2.92e-38 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
MEFDBDGO_02298 5.13e-144 azo1 1.5.1.36, 1.7.1.6 - S ko:K03206,ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
MEFDBDGO_02299 1.27e-98 - - - K - - - Transcriptional regulator
MEFDBDGO_02300 3.99e-96 hsp1 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
MEFDBDGO_02301 0.0 - - - L ko:K07487 - ko00000 Transposase
MEFDBDGO_02302 2.14e-39 - - - S - - - Protein of unknown function (DUF3021)
MEFDBDGO_02303 2.5e-98 - - - K - - - LytTr DNA-binding domain
MEFDBDGO_02304 5.38e-290 - - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
MEFDBDGO_02305 3.98e-68 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
MEFDBDGO_02306 2.79e-274 yycB - - P ko:K03449 - ko00000,ko02000 Transporter, major facilitator family protein
MEFDBDGO_02308 2.16e-204 morA - - S - - - reductase
MEFDBDGO_02309 8.21e-213 - 1.1.1.65 - C ko:K05275 ko00750,ko01100,ko01120,map00750,map01100,map01120 ko00000,ko00001,ko01000 Aldo keto reductase
MEFDBDGO_02310 3.19e-105 - - - F - - - Nucleoside 2-deoxyribosyltransferase like
MEFDBDGO_02311 0.0 l1n 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
MEFDBDGO_02312 4.03e-132 - - - - - - - -
MEFDBDGO_02313 0.0 - - - - - - - -
MEFDBDGO_02314 1.86e-267 - - - C - - - Oxidoreductase
MEFDBDGO_02315 3.28e-193 cbiQ - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
MEFDBDGO_02316 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MEFDBDGO_02317 2.57e-128 - - - S ko:K16924 - ko00000,ko00002,ko02000 UPF0397 protein
MEFDBDGO_02318 4.37e-167 - - - K ko:K03492 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
MEFDBDGO_02319 4.14e-72 - - - K - - - Transcriptional regulator PadR-like family
MEFDBDGO_02320 3.14e-182 - - - - - - - -
MEFDBDGO_02321 7.76e-192 - - - - - - - -
MEFDBDGO_02322 3.37e-115 - - - - - - - -
MEFDBDGO_02323 7.14e-185 dhrS4 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Oxidoreductase, short chain dehydrogenase reductase family protein
MEFDBDGO_02324 1.73e-217 ybhF_1 - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
MEFDBDGO_02325 0.0 - - - M ko:K01992 - ko00000,ko00002,ko02000 Exporter of polyketide antibiotics
MEFDBDGO_02326 1.09e-148 - - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
MEFDBDGO_02327 0.0 etfA 1.3.1.108 - C ko:K03522,ko:K22432 - ko00000,ko01000,ko04147 Electron transfer flavoprotein FAD-binding domain
MEFDBDGO_02328 2.04e-99 - - - T - - - ECF transporter, substrate-specific component
MEFDBDGO_02330 1.85e-121 XK27_02085 - - K - - - Bacterial regulatory proteins, tetR family
MEFDBDGO_02331 2.35e-243 dhaK2 2.7.1.28, 2.7.1.29, 4.6.1.15 - G ko:K00863 ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622 ko00000,ko00001,ko00002,ko01000 Dak1 domain
MEFDBDGO_02332 3.88e-239 dhaK 2.7.1.121 - G ko:K05878 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak1 domain
MEFDBDGO_02333 2.75e-131 dhaL 2.7.1.121 - S ko:K05879 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak2
MEFDBDGO_02334 6.76e-75 dhaM 2.7.1.121 - S ko:K05881 ko00561,map00561 ko00000,ko00001,ko01000,ko02000 PTS system fructose IIA component
MEFDBDGO_02335 1.63e-171 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
MEFDBDGO_02336 2.65e-245 malR1 - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
MEFDBDGO_02337 1.83e-231 yvdE - - K - - - helix_turn _helix lactose operon repressor
MEFDBDGO_02338 0.0 malA1 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain
MEFDBDGO_02339 9.45e-299 mdxE - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
MEFDBDGO_02340 3.74e-302 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MEFDBDGO_02341 2.83e-206 malD - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MEFDBDGO_02342 1.75e-191 malA - - S - - - maltodextrose utilization protein MalA
MEFDBDGO_02343 0.0 malS 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 Glycogen debranching enzyme, glucanotransferase domain
MEFDBDGO_02344 2.44e-267 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MEFDBDGO_02345 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
MEFDBDGO_02346 0.0 - 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Glycosyl hydrolase family 85
MEFDBDGO_02347 8.23e-61 ygbF - - S - - - Sugar efflux transporter for intercellular exchange
MEFDBDGO_02348 2.86e-214 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
MEFDBDGO_02349 0.0 scrA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MEFDBDGO_02350 0.0 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
MEFDBDGO_02351 2.4e-230 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional regulator, LacI family
MEFDBDGO_02352 0.0 - 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
MEFDBDGO_02353 9.92e-212 - 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 nadph quinone reductase
MEFDBDGO_02354 0.0 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
MEFDBDGO_02355 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
MEFDBDGO_02356 5.99e-213 mleR - - K - - - LysR substrate binding domain
MEFDBDGO_02357 0.0 - - - M - - - domain protein
MEFDBDGO_02359 1.03e-201 - - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
MEFDBDGO_02360 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MEFDBDGO_02361 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MEFDBDGO_02362 1.31e-102 yiaC - - K ko:K03826 - ko00000,ko01000 Acetyltransferase (GNAT) domain
MEFDBDGO_02363 1.19e-277 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MEFDBDGO_02364 1.24e-259 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MEFDBDGO_02365 2.73e-147 pgm1 - - G - - - phosphoglycerate mutase
MEFDBDGO_02366 1.01e-228 yghZ - - C ko:K19265 - ko00000,ko01000 Aldo keto reductase family protein
MEFDBDGO_02367 6.33e-46 - - - - - - - -
MEFDBDGO_02368 4.69e-79 - - - S - - - Domain of unknown function (DU1801)
MEFDBDGO_02369 1.03e-206 fbpA - - K - - - Domain of unknown function (DUF814)
MEFDBDGO_02370 2.6e-278 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MEFDBDGO_02371 3.81e-18 - - - - - - - -
MEFDBDGO_02372 3.18e-77 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MEFDBDGO_02373 5.66e-74 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MEFDBDGO_02374 0.0 - - - S ko:K18231,ko:K19349 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ATPases associated with a variety of cellular activities
MEFDBDGO_02375 6.11e-150 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
MEFDBDGO_02376 0.0 - - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
MEFDBDGO_02377 1.43e-131 - - - S ko:K16925 - ko00000,ko00002,ko02000 ABC transporter permease
MEFDBDGO_02378 6.07e-117 gpo 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
MEFDBDGO_02379 5.3e-202 dkgB - - S - - - reductase
MEFDBDGO_02380 5.23e-102 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MEFDBDGO_02381 1.2e-91 - - - - - - - -
MEFDBDGO_02382 2.32e-43 ygzD - - K ko:K07729 - ko00000,ko03000 Transcriptional
MEFDBDGO_02383 3.16e-170 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MEFDBDGO_02384 4.47e-221 - - - P - - - Major Facilitator Superfamily
MEFDBDGO_02385 2.37e-284 - - - C - - - FAD dependent oxidoreductase
MEFDBDGO_02386 3.13e-127 - - - K - - - Helix-turn-helix domain
MEFDBDGO_02387 0.0 pepD1 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
MEFDBDGO_02388 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
MEFDBDGO_02389 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 Mga helix-turn-helix domain
MEFDBDGO_02390 5.33e-103 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MEFDBDGO_02391 2.61e-282 mtlD 1.1.1.17 - C ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 mannitol-1-phosphate 5-dehydrogenase activity
MEFDBDGO_02392 1.21e-111 - - - - - - - -
MEFDBDGO_02393 4.81e-76 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
MEFDBDGO_02394 5.92e-67 - - - - - - - -
MEFDBDGO_02395 2.03e-124 - - - - - - - -
MEFDBDGO_02396 5.79e-88 - - - - - - - -
MEFDBDGO_02397 1.2e-106 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Belongs to the NDK family
MEFDBDGO_02398 0.0 - - - S ko:K13730 ko05100,map05100 ko00000,ko00001 Uncharacterized protein conserved in bacteria (DUF2252)
MEFDBDGO_02399 2.21e-127 - - - S ko:K19784 - ko00000 NADPH-dependent FMN reductase
MEFDBDGO_02400 1.89e-159 - - - K - - - helix_turn_helix gluconate operon transcriptional repressor
MEFDBDGO_02401 4.08e-291 pts3C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MEFDBDGO_02402 6.14e-53 - - - - - - - -
MEFDBDGO_02403 7.59e-269 - - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
MEFDBDGO_02404 3.63e-271 dho 3.5.2.3 - S ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Amidohydrolase family
MEFDBDGO_02405 5.06e-259 selA 2.9.1.1 - H ko:K01042 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko01000 L-seryl-tRNA selenium transferase
MEFDBDGO_02406 1.22e-166 - 4.1.2.14 - S ko:K17463 ko00030,ko01100,ko01120,map00030,map01100,map01120 ko00000,ko00001,ko00002,ko01000 KDGP aldolase
MEFDBDGO_02407 2.02e-245 - 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 pfkB family carbohydrate kinase
MEFDBDGO_02408 3.68e-125 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Bacterial transferase hexapeptide (six repeats)
MEFDBDGO_02409 5.78e-268 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
MEFDBDGO_02410 7.54e-211 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
MEFDBDGO_02411 6.72e-203 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
MEFDBDGO_02412 1.27e-181 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
MEFDBDGO_02413 7.55e-58 - - - S - - - Protein of unknown function (DUF2089)
MEFDBDGO_02414 2.21e-56 - - - - - - - -
MEFDBDGO_02415 1.68e-166 treR - - K ko:K03486 - ko00000,ko03000 UTRA
MEFDBDGO_02416 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
MEFDBDGO_02417 0.0 pts4ABC - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MEFDBDGO_02418 0.0 pts5ABC - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
MEFDBDGO_02419 2.6e-185 - - - - - - - -
MEFDBDGO_02420 3.37e-129 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
MEFDBDGO_02421 9.53e-93 - - - - - - - -
MEFDBDGO_02422 8.9e-96 ywnA - - K - - - Transcriptional regulator
MEFDBDGO_02423 5.2e-156 - - - K - - - Bacterial regulatory proteins, tetR family
MEFDBDGO_02424 5.71e-301 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
MEFDBDGO_02425 1.15e-152 - - - - - - - -
MEFDBDGO_02426 2.92e-57 - - - - - - - -
MEFDBDGO_02427 1.55e-55 - - - - - - - -
MEFDBDGO_02428 0.0 ydiC - - EGP - - - Major Facilitator
MEFDBDGO_02429 2.2e-86 - - - K - - - helix_turn_helix, mercury resistance
MEFDBDGO_02430 2.45e-315 hpk2 - - T - - - Histidine kinase
MEFDBDGO_02431 1.56e-164 rrp2 - - K - - - Transcriptional regulatory protein, C terminal
MEFDBDGO_02432 2.42e-65 - - - - - - - -
MEFDBDGO_02433 1.96e-167 yidA - - K - - - Helix-turn-helix domain, rpiR family
MEFDBDGO_02434 6.86e-311 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MEFDBDGO_02435 3.35e-75 - - - - - - - -
MEFDBDGO_02436 2.87e-56 - - - - - - - -
MEFDBDGO_02437 1.76e-236 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
MEFDBDGO_02438 0.0 loxD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD linked oxidases, C-terminal domain
MEFDBDGO_02439 1.49e-63 - - - - - - - -
MEFDBDGO_02440 2.04e-158 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
MEFDBDGO_02441 1.17e-135 - - - K - - - transcriptional regulator
MEFDBDGO_02442 0.0 ydgH - - S ko:K06994 - ko00000 MMPL family
MEFDBDGO_02443 1.18e-138 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
MEFDBDGO_02444 0.0 - - - S - - - Leucine-rich repeat (LRR) protein
MEFDBDGO_02445 1.01e-292 vex3 - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
MEFDBDGO_02446 4.87e-156 vex2 - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
MEFDBDGO_02447 1.13e-171 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
MEFDBDGO_02448 2.63e-154 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
MEFDBDGO_02449 7.98e-80 - - - M - - - Lysin motif
MEFDBDGO_02450 1.43e-82 - - - M - - - LysM domain protein
MEFDBDGO_02451 4.2e-88 gcsH1 - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Glycine cleavage H-protein
MEFDBDGO_02452 4.47e-229 - - - - - - - -
MEFDBDGO_02453 6.88e-170 - - - - - - - -
MEFDBDGO_02454 0.0 uvrB3 3.1.12.1 - KL ko:K07464 - ko00000,ko01000,ko02048 DEAD_2
MEFDBDGO_02455 2.03e-75 - - - - - - - -
MEFDBDGO_02456 3.74e-284 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MEFDBDGO_02457 1.08e-101 - - - S ko:K02348 - ko00000 GNAT family
MEFDBDGO_02458 1.24e-99 - - - K - - - Transcriptional regulator
MEFDBDGO_02459 9.59e-288 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
MEFDBDGO_02460 6.01e-51 - - - - - - - -
MEFDBDGO_02462 1.04e-35 - - - - - - - -
MEFDBDGO_02463 1.86e-31 - - - U - - - Preprotein translocase subunit SecB
MEFDBDGO_02464 5.3e-265 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MEFDBDGO_02465 9.24e-180 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MEFDBDGO_02466 9e-190 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MEFDBDGO_02467 1.46e-262 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MEFDBDGO_02468 1.5e-124 - - - K - - - Cupin domain
MEFDBDGO_02469 8.08e-110 - - - S - - - ASCH
MEFDBDGO_02470 1.88e-111 - - - K - - - GNAT family
MEFDBDGO_02471 2.14e-117 - - - K - - - acetyltransferase
MEFDBDGO_02472 2.06e-30 - - - - - - - -
MEFDBDGO_02473 5.05e-79 - - - K ko:K07979 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
MEFDBDGO_02474 1.85e-208 - - - V ko:K01990,ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MEFDBDGO_02475 1.08e-243 - - - - - - - -
MEFDBDGO_02476 0.0 acdH 1.1.1.1, 1.2.1.10, 1.2.1.87 - C ko:K04072,ko:K13922 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Aldehyde dehydrogenase family
MEFDBDGO_02477 8.16e-207 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
MEFDBDGO_02479 2.36e-305 xylP1 - - G - - - MFS/sugar transport protein
MEFDBDGO_02480 1.43e-170 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 prohibitin homologues
MEFDBDGO_02481 7.28e-42 - - - - - - - -
MEFDBDGO_02482 0.0 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
MEFDBDGO_02483 6.4e-54 - - - - - - - -
MEFDBDGO_02484 1.54e-123 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
MEFDBDGO_02485 1.49e-227 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MEFDBDGO_02486 1.4e-81 - - - S - - - CHY zinc finger
MEFDBDGO_02487 2.21e-284 mtnE - - E ko:K08969 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
MEFDBDGO_02488 6.39e-280 - - - - - - - -
MEFDBDGO_02489 8.13e-199 tagG - - U ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
MEFDBDGO_02490 9.42e-258 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
MEFDBDGO_02491 2.76e-59 - - - - - - - -
MEFDBDGO_02492 2.39e-121 - - - K - - - Transcriptional regulator PadR-like family
MEFDBDGO_02493 0.0 - - - P - - - Major Facilitator Superfamily
MEFDBDGO_02494 1.05e-308 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
MEFDBDGO_02495 9e-227 hicD1 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
MEFDBDGO_02496 8.95e-60 - - - - - - - -
MEFDBDGO_02497 1.05e-132 zmp1 - - O - - - Zinc-dependent metalloprotease
MEFDBDGO_02498 7.16e-155 rpiA2 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
MEFDBDGO_02499 0.0 sufI - - Q - - - Multicopper oxidase
MEFDBDGO_02500 5.34e-72 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
MEFDBDGO_02501 1.31e-124 yxkA - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
MEFDBDGO_02502 1.61e-294 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
MEFDBDGO_02503 5.89e-108 - - - K - - - Winged helix-turn-helix transcription repressor, HrcA DNA-binding
MEFDBDGO_02504 2.16e-103 - - - - - - - -
MEFDBDGO_02505 2.43e-103 accB3 - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MEFDBDGO_02506 8.62e-223 rihA 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
MEFDBDGO_02507 1.77e-207 yneD - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
MEFDBDGO_02508 3.67e-154 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MEFDBDGO_02509 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
MEFDBDGO_02510 3.62e-249 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MEFDBDGO_02511 5.74e-108 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
MEFDBDGO_02512 4.66e-131 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 Ribosomal-protein-alanine acetyltransferase
MEFDBDGO_02513 3.25e-165 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
MEFDBDGO_02514 3.46e-242 phnD - - P ko:K02044 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphonate ABC transporter
MEFDBDGO_02515 9.33e-177 phnC 3.6.3.28 - P ko:K02041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MEFDBDGO_02516 5.35e-177 phnE2 - - U ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphonate ABC transporter permease
MEFDBDGO_02517 1.36e-183 phnE1 - - U ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MEFDBDGO_02518 1.97e-187 phnX 3.11.1.1 - E ko:K05306 ko00440,ko01100,ko01120,map00440,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the HAD-like hydrolase superfamily. PhnX family
MEFDBDGO_02519 2.18e-269 phnW 2.6.1.37 - E ko:K03430 ko00440,ko01100,ko01120,map00440,map01100,map01120 ko00000,ko00001,ko01000,ko01007 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily
MEFDBDGO_02520 2.86e-245 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
MEFDBDGO_02521 3.17e-191 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
MEFDBDGO_02522 2.64e-213 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MEFDBDGO_02523 8.46e-77 yabA - - L - - - Involved in initiation control of chromosome replication
MEFDBDGO_02524 1.92e-238 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
MEFDBDGO_02525 1.39e-70 yaaQ - - S - - - Cyclic-di-AMP receptor
MEFDBDGO_02526 2.22e-153 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MEFDBDGO_02527 1.01e-51 yaaL - - S - - - Protein of unknown function (DUF2508)
MEFDBDGO_02528 6.22e-140 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MEFDBDGO_02529 2.05e-62 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MEFDBDGO_02530 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MEFDBDGO_02531 7.57e-119 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MEFDBDGO_02532 6.7e-141 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
MEFDBDGO_02533 8.42e-50 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
MEFDBDGO_02534 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MEFDBDGO_02535 2.47e-253 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MEFDBDGO_02536 5.82e-141 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
MEFDBDGO_02537 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
MEFDBDGO_02538 1.22e-227 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
MEFDBDGO_02539 3.59e-212 fabK 1.3.1.9 - S ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Nitronate monooxygenase
MEFDBDGO_02540 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
MEFDBDGO_02541 2.33e-145 - - - S ko:K03975 - ko00000 SNARE associated Golgi protein
MEFDBDGO_02542 4.16e-227 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
MEFDBDGO_02543 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
MEFDBDGO_02544 2.07e-161 gpm2 - - G - - - Phosphoglycerate mutase family
MEFDBDGO_02545 1.35e-165 pgm3 - - G - - - Phosphoglycerate mutase family
MEFDBDGO_02546 1.61e-36 - - - - - - - -
MEFDBDGO_02547 3.5e-64 sugE - - U ko:K11741 - ko00000,ko02000 Multidrug resistance protein
MEFDBDGO_02548 4.6e-102 rppH3 - - F - - - NUDIX domain
MEFDBDGO_02549 5.95e-300 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MEFDBDGO_02550 1.81e-128 - - - K - - - Bacterial regulatory proteins, tetR family
MEFDBDGO_02551 2.93e-109 - - - S ko:K07090 - ko00000 membrane transporter protein
MEFDBDGO_02552 3.22e-269 - - - EGP - - - Major Facilitator Superfamily
MEFDBDGO_02553 3.08e-93 - - - K - - - MarR family
MEFDBDGO_02554 8.87e-191 - - - S - - - Sulfite exporter TauE/SafE
MEFDBDGO_02555 2.55e-95 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
MEFDBDGO_02556 9.38e-317 steT - - E ko:K03294 - ko00000 amino acid
MEFDBDGO_02557 9.06e-182 - 3.5.1.105 - G ko:K03478 - ko00000,ko01000 YdjC-like protein
MEFDBDGO_02558 0.0 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
MEFDBDGO_02559 1.91e-197 - - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
MEFDBDGO_02560 1.22e-108 - - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
MEFDBDGO_02561 1.27e-141 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MEFDBDGO_02562 8.99e-140 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MEFDBDGO_02563 3.39e-190 glnH - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
MEFDBDGO_02564 9.36e-172 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MEFDBDGO_02566 5.2e-54 - - - - - - - -
MEFDBDGO_02567 1.03e-217 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MEFDBDGO_02568 3.21e-268 aspC 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
MEFDBDGO_02569 6.94e-146 gph1 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 HAD hydrolase, family IA, variant
MEFDBDGO_02571 1.01e-188 - - - - - - - -
MEFDBDGO_02572 8.84e-18 - 3.2.1.14 GH18 - ko:K01183 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 -
MEFDBDGO_02573 2.02e-106 zur - - P ko:K02076,ko:K03711 - ko00000,ko03000 Belongs to the Fur family
MEFDBDGO_02574 7.32e-136 gmk2 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Guanylate kinase
MEFDBDGO_02575 1.48e-27 - - - - - - - -
MEFDBDGO_02576 7.48e-96 - - - F - - - Nudix hydrolase
MEFDBDGO_02577 7.76e-193 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
MEFDBDGO_02578 2.49e-114 - - - - - - - -
MEFDBDGO_02579 0.0 yhdG - - E ko:K03294 - ko00000 Amino Acid
MEFDBDGO_02580 2.45e-63 - - - - - - - -
MEFDBDGO_02581 1.89e-90 - - - O - - - OsmC-like protein
MEFDBDGO_02582 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
MEFDBDGO_02583 0.0 oatA - - I - - - Acyltransferase
MEFDBDGO_02584 1.23e-229 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MEFDBDGO_02585 6.37e-232 pepR 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
MEFDBDGO_02586 0.0 pox2 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
MEFDBDGO_02587 5.47e-198 ribC1 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
MEFDBDGO_02588 0.0 pox1 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
MEFDBDGO_02589 1.79e-287 pbuG - - S ko:K06901 - ko00000,ko02000 permease
MEFDBDGO_02590 1.36e-27 - - - - - - - -
MEFDBDGO_02591 6.16e-107 - - - K - - - Transcriptional regulator
MEFDBDGO_02592 6.68e-197 licD - - M ko:K07271 - ko00000,ko01000 LicD family
MEFDBDGO_02593 0.0 ppx3 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
MEFDBDGO_02594 0.0 ppk 2.7.4.1 - P ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MEFDBDGO_02595 4.45e-226 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
MEFDBDGO_02596 1.06e-314 - - - EGP - - - Major Facilitator
MEFDBDGO_02597 3.45e-116 - - - V - - - VanZ like family
MEFDBDGO_02598 3.88e-46 - - - - - - - -
MEFDBDGO_02599 5.45e-94 spx1 - - P ko:K16509 - ko00000 ArsC family
MEFDBDGO_02601 5.03e-183 - - - - - - - -
MEFDBDGO_02602 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MEFDBDGO_02603 2.09e-42 - - - G ko:K08217 - br01600,ko00000,ko01504,ko02000 Transmembrane secretion effector
MEFDBDGO_02604 7.34e-180 - - - EGP - - - Transmembrane secretion effector
MEFDBDGO_02605 7.06e-169 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
MEFDBDGO_02606 2.49e-95 - - - - - - - -
MEFDBDGO_02607 3.38e-70 - - - - - - - -
MEFDBDGO_02608 2.07e-263 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
MEFDBDGO_02609 1.21e-135 - - - K - - - Bacterial regulatory proteins, tetR family
MEFDBDGO_02610 8.04e-190 - 3.1.3.23 - S ko:K07757 - ko00000,ko01000 Sucrose-6F-phosphate phosphohydrolase
MEFDBDGO_02611 5.44e-159 - - - T - - - EAL domain
MEFDBDGO_02612 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MEFDBDGO_02613 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MEFDBDGO_02614 2.18e-182 ybbR - - S - - - YbbR-like protein
MEFDBDGO_02615 8.33e-192 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MEFDBDGO_02616 6.9e-157 - - - S - - - Protein of unknown function (DUF1361)
MEFDBDGO_02617 1.25e-118 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
MEFDBDGO_02618 0.0 yvgP - - P ko:K03316 - ko00000 Sodium proton antiporter
MEFDBDGO_02619 6.24e-214 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
MEFDBDGO_02620 3.09e-213 ysjB - - S ko:K03810 - ko00000 Oxidoreductase family, NAD-binding Rossmann fold
MEFDBDGO_02621 2.53e-198 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
MEFDBDGO_02622 7.18e-131 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
MEFDBDGO_02623 2.52e-114 - - - J - - - Acetyltransferase (GNAT) domain
MEFDBDGO_02624 1.29e-105 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
MEFDBDGO_02625 2.89e-226 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
MEFDBDGO_02626 1.4e-174 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MEFDBDGO_02627 1.98e-199 ycsE - - S - - - Sucrose-6F-phosphate phosphohydrolase
MEFDBDGO_02628 5.62e-137 - - - - - - - -
MEFDBDGO_02629 9.36e-171 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MEFDBDGO_02630 0.0 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MEFDBDGO_02631 0.0 - - - M - - - Domain of unknown function (DUF5011)
MEFDBDGO_02632 2.4e-107 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MEFDBDGO_02633 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MEFDBDGO_02634 1.1e-178 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Serine aminopeptidase, S33
MEFDBDGO_02635 1.76e-43 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
MEFDBDGO_02636 0.0 eriC - - P ko:K03281 - ko00000 chloride
MEFDBDGO_02637 5.11e-171 - - - - - - - -
MEFDBDGO_02638 0.0 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MEFDBDGO_02639 7.15e-179 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MEFDBDGO_02640 2.16e-284 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
MEFDBDGO_02641 2.02e-245 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MEFDBDGO_02642 5.75e-242 cggR - - K ko:K05311 - ko00000,ko03000 Putative sugar-binding domain
MEFDBDGO_02643 1.14e-311 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 Sigma-54 factor, core binding domain
MEFDBDGO_02645 5.11e-133 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MEFDBDGO_02646 1.55e-225 - 1.1.1.26 - CH ko:K00015 ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MEFDBDGO_02647 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MEFDBDGO_02648 1.21e-215 whiA - - K ko:K09762 - ko00000 May be required for sporulation
MEFDBDGO_02649 4.56e-243 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
MEFDBDGO_02650 1.71e-207 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
MEFDBDGO_02651 8.62e-114 - - - S - - - Short repeat of unknown function (DUF308)
MEFDBDGO_02652 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
MEFDBDGO_02653 7.5e-302 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
MEFDBDGO_02654 2.21e-113 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MEFDBDGO_02655 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MEFDBDGO_02656 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MEFDBDGO_02657 9.45e-152 yfbR - - S ko:K07023 - ko00000 HD containing hydrolase-like enzyme
MEFDBDGO_02658 5.33e-268 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 transporter
MEFDBDGO_02659 1.89e-134 aad 3.4.13.22 - E ko:K08641 ko01502,ko02020,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
MEFDBDGO_02660 0.0 nox2 - - S - - - Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
MEFDBDGO_02661 5.9e-170 - - - T - - - Putative diguanylate phosphodiesterase
MEFDBDGO_02662 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
MEFDBDGO_02663 7.54e-99 - - - S - - - Protein of unknown function (DUF3290)
MEFDBDGO_02664 4.31e-141 yviA - - S - - - Protein of unknown function (DUF421)
MEFDBDGO_02665 8.65e-226 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MEFDBDGO_02666 0.0 nox - - C - - - NADH oxidase
MEFDBDGO_02667 6.37e-160 - - - T - - - Putative diguanylate phosphodiesterase
MEFDBDGO_02668 1.13e-218 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
MEFDBDGO_02669 2.82e-235 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
MEFDBDGO_02670 6.26e-213 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MEFDBDGO_02671 2.55e-225 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MEFDBDGO_02672 2.87e-71 yvlD - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
MEFDBDGO_02673 2.78e-65 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 positive regulation of macromolecule biosynthetic process
MEFDBDGO_02674 1.55e-150 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
MEFDBDGO_02675 2.31e-179 pstB1 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MEFDBDGO_02676 9.78e-190 pstB2 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MEFDBDGO_02677 5.04e-200 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
MEFDBDGO_02678 2.22e-206 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
MEFDBDGO_02679 6.91e-201 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
MEFDBDGO_02680 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MEFDBDGO_02681 1.49e-170 phoP - - K ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
MEFDBDGO_02682 1.28e-276 minJ - - O - - - Domain present in PSD-95, Dlg, and ZO-1/2.
MEFDBDGO_02683 2.3e-255 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MEFDBDGO_02684 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MEFDBDGO_02685 1.27e-129 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MEFDBDGO_02686 3.43e-163 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
MEFDBDGO_02687 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
MEFDBDGO_02688 3.7e-149 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
MEFDBDGO_02689 6.57e-199 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
MEFDBDGO_02690 7.29e-247 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 transferase
MEFDBDGO_02691 0.0 ydaO - - E - - - amino acid
MEFDBDGO_02692 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MEFDBDGO_02693 9.82e-55 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MEFDBDGO_02694 1.68e-140 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
MEFDBDGO_02695 1.29e-142 XK27_07075 - - V ko:K07052 - ko00000 CAAX protease self-immunity
MEFDBDGO_02696 1.85e-75 - - - K - - - HxlR-like helix-turn-helix
MEFDBDGO_02697 1.11e-300 yceJ - - EGP ko:K08221 - ko00000,ko02000 transporter
MEFDBDGO_02698 3.5e-299 - - - S - - - Cysteine-rich secretory protein family
MEFDBDGO_02699 3.61e-61 - - - S - - - MORN repeat
MEFDBDGO_02700 0.0 XK27_09800 - - I - - - Acyltransferase family
MEFDBDGO_02701 1.81e-50 ydaS - - S - - - Transglycosylase associated protein
MEFDBDGO_02702 1.95e-116 - - - - - - - -
MEFDBDGO_02703 5.74e-32 - - - - - - - -
MEFDBDGO_02704 1.1e-93 asp1 - - S - - - Asp23 family, cell envelope-related function
MEFDBDGO_02705 1.04e-94 asp2 - - S - - - Asp23 family, cell envelope-related function
MEFDBDGO_02706 3.75e-188 yisK 3.7.1.5, 4.1.1.68 - Q ko:K05921,ko:K16164 ko00350,ko01100,ko01120,ko01220,map00350,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Fumarylacetoacetate (FAA) hydrolase family
MEFDBDGO_02707 2.11e-211 yjdB - - S - - - Domain of unknown function (DUF4767)
MEFDBDGO_02708 5.21e-62 - 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
MEFDBDGO_02709 2.66e-132 - - - G - - - Glycogen debranching enzyme
MEFDBDGO_02710 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
MEFDBDGO_02712 0.0 - - - M - - - domain protein
MEFDBDGO_02713 2.14e-174 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
MEFDBDGO_02714 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 C-terminal domain of alpha-glycerophosphate oxidase
MEFDBDGO_02715 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MEFDBDGO_02716 0.0 gshR 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
MEFDBDGO_02717 2.7e-230 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MEFDBDGO_02718 0.0 proWX - - EM ko:K05845,ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MEFDBDGO_02719 1.42e-102 - 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA-DNA hybrid ribonuclease activity
MEFDBDGO_02720 5.09e-264 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MEFDBDGO_02721 0.0 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
MEFDBDGO_02722 1.39e-190 - - - S - - - hydrolase
MEFDBDGO_02723 2.35e-212 - - - K - - - Transcriptional regulator
MEFDBDGO_02724 4.15e-188 - 3.1.3.102, 3.1.3.104, 3.1.3.23 - G ko:K07757,ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
MEFDBDGO_02725 1.51e-260 - - - EGP - - - Transporter, major facilitator family protein
MEFDBDGO_02726 4.56e-154 lacA 2.3.1.18, 2.3.1.79 - S ko:K00633,ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
MEFDBDGO_02727 0.0 citF 2.8.3.10 - H ko:K01643 ko02020,map02020 ko00000,ko00001,ko01000 Citrate (pro-3S)-lyase alpha chain
MEFDBDGO_02728 3.32e-210 citE 4.1.3.34 - G ko:K01644 ko02020,map02020 ko00000,ko00001,ko01000 Belongs to the HpcH HpaI aldolase family
MEFDBDGO_02729 1.23e-58 citD - - C ko:K01646 ko02020,map02020 ko00000,ko00001 Covalent carrier of the coenzyme of citrate lyase
MEFDBDGO_02730 5.31e-242 citC 6.2.1.22 - H ko:K01910 ko02020,map02020 ko00000,ko00001,ko01000 Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
MEFDBDGO_02731 3.88e-264 mae 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme, NAD binding domain
MEFDBDGO_02732 8.69e-230 citR - - K - - - sugar-binding domain protein
MEFDBDGO_02733 0.0 citP - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
MEFDBDGO_02734 9.2e-215 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
MEFDBDGO_02735 4.8e-66 - - - - - - - -
MEFDBDGO_02736 5.19e-223 mntA - - P ko:K19975,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
MEFDBDGO_02737 3.54e-180 mtsB - - U ko:K19972,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
MEFDBDGO_02738 2.04e-170 mntB 3.6.3.35 - P ko:K02074,ko:K09820,ko:K19973 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
MEFDBDGO_02739 4.49e-196 citG 2.4.2.52 - H ko:K05966 ko02020,map02020 ko00000,ko00001,ko01000 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
MEFDBDGO_02740 6.07e-252 - - - K - - - Helix-turn-helix domain
MEFDBDGO_02741 5.21e-226 ttdA 4.2.1.32 - C ko:K03779 ko00630,map00630 ko00000,ko00001,ko01000 Fumarate hydratase (Fumerase)
MEFDBDGO_02742 1.41e-147 - 4.2.1.2, 4.2.1.32 - C ko:K01676,ko:K03780 ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible hydration of fumarate to (S)- malate
MEFDBDGO_02743 1.51e-69 yitW - - S - - - Iron-sulfur cluster assembly protein
MEFDBDGO_02744 5.35e-310 - - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
MEFDBDGO_02745 3.51e-251 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MEFDBDGO_02746 3.3e-235 aroF 2.5.1.54 - E ko:K03856 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 DAHP synthetase I family
MEFDBDGO_02747 4.94e-213 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MEFDBDGO_02748 0.0 tkt2 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MEFDBDGO_02749 1.35e-261 - - - C - - - Belongs to the LDH2 MDH2 oxidoreductase family
MEFDBDGO_02750 7.05e-235 - - - S - - - Membrane
MEFDBDGO_02751 8.51e-210 yitS - - S - - - Uncharacterised protein, DegV family COG1307
MEFDBDGO_02752 8.98e-86 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
MEFDBDGO_02753 4.58e-103 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MEFDBDGO_02754 3.06e-194 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MEFDBDGO_02755 2.39e-184 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MEFDBDGO_02756 2.01e-211 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MEFDBDGO_02757 1.63e-196 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MEFDBDGO_02758 1.07e-264 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MEFDBDGO_02759 9.15e-194 - - - S - - - FMN_bind
MEFDBDGO_02760 0.0 ndh 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
MEFDBDGO_02761 5.37e-112 - - - S - - - NusG domain II
MEFDBDGO_02762 1.41e-122 hepA 2.5.1.30 - S ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase component I
MEFDBDGO_02763 1.02e-233 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
MEFDBDGO_02764 7.76e-81 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
MEFDBDGO_02765 2.19e-220 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MEFDBDGO_02766 7.71e-82 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MEFDBDGO_02767 9.65e-79 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MEFDBDGO_02768 1.19e-45 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MEFDBDGO_02769 1.84e-160 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MEFDBDGO_02770 5.95e-300 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MEFDBDGO_02771 1.32e-91 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
MEFDBDGO_02772 8.44e-34 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
MEFDBDGO_02773 5.32e-109 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MEFDBDGO_02774 1.75e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MEFDBDGO_02775 2.14e-123 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MEFDBDGO_02776 4.99e-88 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MEFDBDGO_02777 3.53e-123 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MEFDBDGO_02778 4.1e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MEFDBDGO_02779 2.98e-78 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MEFDBDGO_02780 1.96e-54 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MEFDBDGO_02781 1.11e-33 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
MEFDBDGO_02782 8.29e-100 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MEFDBDGO_02783 5.46e-152 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MEFDBDGO_02784 3.59e-69 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MEFDBDGO_02785 1.85e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MEFDBDGO_02786 6.61e-193 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MEFDBDGO_02787 2.27e-59 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MEFDBDGO_02788 9.83e-141 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
MEFDBDGO_02789 4.34e-145 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MEFDBDGO_02790 4.46e-66 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
MEFDBDGO_02791 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MEFDBDGO_02792 1.19e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MEFDBDGO_02793 4.19e-92 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MEFDBDGO_02794 8.58e-149 comC 3.4.23.43 - NOU ko:K02236 - ko00000,ko00002,ko01000,ko02044 Bacterial Peptidase A24 N-terminal domain
MEFDBDGO_02795 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MEFDBDGO_02796 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MEFDBDGO_02797 1.16e-140 - - - K - - - Bacterial regulatory proteins, tetR family
MEFDBDGO_02798 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MEFDBDGO_02799 9.78e-102 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
MEFDBDGO_02807 1.62e-294 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MEFDBDGO_02808 1.11e-148 dgk2 - - F - - - deoxynucleoside kinase
MEFDBDGO_02809 1.29e-153 dacB 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
MEFDBDGO_02810 0.0 lysP - - E ko:K03293,ko:K11733 - ko00000,ko02000 amino acid
MEFDBDGO_02811 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
MEFDBDGO_02812 1.7e-118 - - - K - - - Transcriptional regulator
MEFDBDGO_02813 1.23e-128 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
MEFDBDGO_02814 3.88e-198 - - - I - - - alpha/beta hydrolase fold
MEFDBDGO_02815 2.05e-153 - - - I - - - phosphatase
MEFDBDGO_02816 2.34e-242 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
MEFDBDGO_02817 7.76e-100 - - - S - - - Threonine/Serine exporter, ThrE
MEFDBDGO_02818 4.6e-169 - - - S - - - Putative threonine/serine exporter
MEFDBDGO_02819 1.78e-42 cspC - - K ko:K03704 - ko00000,ko03000 Cold shock protein
MEFDBDGO_02820 2.94e-155 mntR - - K ko:K03709 - ko00000,ko03000 iron dependent repressor
MEFDBDGO_02821 1.36e-77 - - - - - - - -
MEFDBDGO_02822 7.79e-112 - - - K - - - MerR HTH family regulatory protein
MEFDBDGO_02823 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
MEFDBDGO_02824 2.72e-152 - - - S - - - Domain of unknown function (DUF4811)
MEFDBDGO_02825 9.04e-179 - - - - - - - -
MEFDBDGO_02826 1.75e-47 - - - K - - - MerR HTH family regulatory protein
MEFDBDGO_02827 1.43e-155 azlC - - E - - - branched-chain amino acid
MEFDBDGO_02828 2.41e-66 azlD - - S - - - Branched-chain amino acid transport protein (AzlD)
MEFDBDGO_02829 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
MEFDBDGO_02830 1.2e-281 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Amino acid kinase family
MEFDBDGO_02831 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MEFDBDGO_02832 0.0 xylP2 - - G - - - symporter
MEFDBDGO_02833 8.55e-246 - - - I - - - alpha/beta hydrolase fold
MEFDBDGO_02834 3.33e-64 - - - - - - - -
MEFDBDGO_02835 6.13e-156 gpm5 - - G - - - Phosphoglycerate mutase family
MEFDBDGO_02836 1.22e-132 - - - K - - - FR47-like protein
MEFDBDGO_02837 8.44e-163 yibF - - S - - - overlaps another CDS with the same product name
MEFDBDGO_02838 3.42e-280 yibE - - S - - - overlaps another CDS with the same product name
MEFDBDGO_02839 6.48e-243 - - - - - - - -
MEFDBDGO_02840 1.44e-179 - - - S - - - NADPH-dependent FMN reductase
MEFDBDGO_02841 5.06e-68 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
MEFDBDGO_02842 1.65e-209 rluD2 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
MEFDBDGO_02843 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
MEFDBDGO_02844 4.95e-44 - - - L - - - leucine-zipper of insertion element IS481
MEFDBDGO_02845 9.05e-55 - - - - - - - -
MEFDBDGO_02846 5.38e-290 - - - L - - - DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MEFDBDGO_02847 0.0 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
MEFDBDGO_02848 2.78e-254 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
MEFDBDGO_02849 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
MEFDBDGO_02850 1.41e-150 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MEFDBDGO_02851 2.49e-105 - - - K - - - Transcriptional regulator
MEFDBDGO_02853 0.0 - - - C - - - FMN_bind
MEFDBDGO_02854 1.37e-220 - - - K - - - Transcriptional regulator
MEFDBDGO_02855 1.09e-123 - - - K - - - Helix-turn-helix domain
MEFDBDGO_02856 1.06e-179 - - - K - - - sequence-specific DNA binding
MEFDBDGO_02857 1.27e-115 - - - S - - - AAA domain
MEFDBDGO_02858 1.42e-08 - - - - - - - -
MEFDBDGO_02859 0.0 - - - M - - - MucBP domain
MEFDBDGO_02860 9.74e-86 - - - M - - - MucBP domain
MEFDBDGO_02861 5.66e-118 XK27_09665 - - G ko:K15640 - ko00000 Phosphoglycerate mutase family
MEFDBDGO_02862 1.01e-226 - - - F ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
MEFDBDGO_02863 1.78e-88 - - - L - - - nuclease
MEFDBDGO_02864 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MEFDBDGO_02865 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
MEFDBDGO_02866 5.33e-243 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MEFDBDGO_02867 1.93e-209 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MEFDBDGO_02868 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MEFDBDGO_02869 4.3e-124 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
MEFDBDGO_02870 0.0 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MEFDBDGO_02871 1.07e-103 yabR - - J ko:K07571 - ko00000 RNA binding
MEFDBDGO_02872 1.17e-82 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
MEFDBDGO_02874 7.72e-57 yabO - - J - - - S4 domain protein
MEFDBDGO_02875 0.0 yabM - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
MEFDBDGO_02876 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MEFDBDGO_02877 1.43e-129 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MEFDBDGO_02878 2.79e-226 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
MEFDBDGO_02879 0.0 - - - S - - - Putative peptidoglycan binding domain
MEFDBDGO_02880 1.98e-147 - - - S - - - (CBS) domain
MEFDBDGO_02881 8.1e-157 pepL 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
MEFDBDGO_02882 1.23e-209 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
MEFDBDGO_02883 1.3e-110 queT - - S - - - QueT transporter
MEFDBDGO_02884 2.63e-241 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MEFDBDGO_02885 1.74e-273 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine
MEFDBDGO_02886 9.62e-166 argB 2.7.2.8 - F ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
MEFDBDGO_02887 9.73e-294 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MEFDBDGO_02888 3.61e-244 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MEFDBDGO_02889 3.7e-260 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
MEFDBDGO_02890 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
MEFDBDGO_02891 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
MEFDBDGO_02892 4.28e-84 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
MEFDBDGO_02893 1.43e-274 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MEFDBDGO_02894 9.32e-81 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MEFDBDGO_02895 0.0 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MEFDBDGO_02896 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MEFDBDGO_02897 1.84e-189 - - - - - - - -
MEFDBDGO_02898 4.58e-194 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
MEFDBDGO_02899 5.35e-121 lemA - - S ko:K03744 - ko00000 LemA family
MEFDBDGO_02900 3.14e-164 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
MEFDBDGO_02901 1.05e-273 - - - J - - - translation release factor activity
MEFDBDGO_02902 1.91e-55 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
MEFDBDGO_02903 6.26e-306 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MEFDBDGO_02904 8.48e-302 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MEFDBDGO_02905 4.01e-36 - - - - - - - -
MEFDBDGO_02906 6.59e-170 - - - S - - - YheO-like PAS domain
MEFDBDGO_02907 2.81e-202 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
MEFDBDGO_02908 1.52e-158 sdhB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
MEFDBDGO_02909 2.28e-290 sdaC - - E ko:K03837 - ko00000,ko02000 amino acid
MEFDBDGO_02910 5.84e-312 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MEFDBDGO_02911 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MEFDBDGO_02912 2.96e-89 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MEFDBDGO_02913 2.87e-101 ywiB - - S - - - Domain of unknown function (DUF1934)
MEFDBDGO_02914 8.97e-200 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 biotin lipoate A B protein ligase
MEFDBDGO_02915 0.0 ywfO - - S ko:K06885 - ko00000 HD domain protein
MEFDBDGO_02916 4.15e-191 yxeH - - S - - - hydrolase
MEFDBDGO_02917 4.31e-179 - - - - - - - -
MEFDBDGO_02918 1.34e-234 - - - S - - - DUF218 domain
MEFDBDGO_02919 3.26e-228 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MEFDBDGO_02920 1.1e-193 bla1 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
MEFDBDGO_02921 3.28e-298 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MEFDBDGO_02922 1.96e-189 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
MEFDBDGO_02923 5.3e-49 - - - - - - - -
MEFDBDGO_02924 8.4e-57 - - - S - - - ankyrin repeats
MEFDBDGO_02925 5.67e-27 - - - M ko:K21493 - ko00000,ko01000,ko02048 self proteolysis
MEFDBDGO_02926 6.39e-169 znuB - - U ko:K02075,ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
MEFDBDGO_02927 8.05e-166 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
MEFDBDGO_02928 1.56e-229 - - - S ko:K06889 - ko00000 Prolyl oligopeptidase family
MEFDBDGO_02929 1.31e-208 ispE 2.7.1.148 - F ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MEFDBDGO_02930 6.87e-50 veg - - S - - - Biofilm formation stimulator VEG
MEFDBDGO_02931 2.5e-203 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MEFDBDGO_02932 1.6e-127 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MEFDBDGO_02933 1.63e-187 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
MEFDBDGO_02934 4.08e-270 - - - EGP ko:K02030 - ko00000,ko00002,ko02000 Drug resistance transporter Bcr CflA subfamily
MEFDBDGO_02935 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MEFDBDGO_02936 5.43e-91 - - - F - - - DNA mismatch repair protein MutT
MEFDBDGO_02937 1.12e-205 yunF - - F - - - Protein of unknown function DUF72
MEFDBDGO_02938 6.15e-171 cobB - - K ko:K12410 - ko00000,ko01000 SIR2 family
MEFDBDGO_02939 4.65e-229 - - - - - - - -
MEFDBDGO_02940 5.59e-290 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
MEFDBDGO_02941 1.36e-214 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
MEFDBDGO_02942 5.08e-194 - - - S - - - Psort location Cytoplasmic, score
MEFDBDGO_02943 8.64e-263 - - - - - - - -
MEFDBDGO_02944 7.22e-245 dus - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MEFDBDGO_02945 9.75e-175 yecA - - K - - - Helix-turn-helix domain, rpiR family
MEFDBDGO_02946 6.97e-209 - - - GK - - - ROK family
MEFDBDGO_02947 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MEFDBDGO_02948 4.22e-264 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MEFDBDGO_02949 3.44e-38 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MEFDBDGO_02950 8.38e-98 - - - S - - - Domain of unknown function (DUF3284)
MEFDBDGO_02951 9.68e-34 - - - - - - - -
MEFDBDGO_02952 0.0 chbC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MEFDBDGO_02953 2.69e-166 - - - K - - - UbiC transcription regulator-associated domain protein
MEFDBDGO_02954 8.19e-244 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
MEFDBDGO_02955 9.73e-180 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Carbon-nitrogen hydrolase
MEFDBDGO_02956 0.0 - - - L - - - DNA helicase

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)