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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HPADDANE_00001	1.62e-294	-	-	-	S	ko:K07133	-	ko00000	AAA domain
HPADDANE_00002	0.0	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
HPADDANE_00003	0.0	ppc	4.1.1.31	-	H	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HPADDANE_00004	0.0	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HPADDANE_00005	0.0	-	-	-	E	ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HPADDANE_00006	5.49e-237	-	-	-	S	-	-	-	Protein conserved in bacteria
HPADDANE_00007	0.0	-	-	-	S	-	-	-	Amidohydrolase family
HPADDANE_00008	2.41e-260	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HPADDANE_00009	4.19e-58	-	-	-	S	-	-	-	Protein of unknown function (DUF3073)
HPADDANE_00010	3.11e-145	-	-	-	K	-	-	-	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HPADDANE_00011	9.19e-266	-	-	-	T	-	-	-	Histidine kinase
HPADDANE_00012	1.66e-305	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HPADDANE_00013	1.1e-97	-	-	-	I	-	-	-	Sterol carrier protein
HPADDANE_00014	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HPADDANE_00015	2.06e-46	-	-	-	-	-	-	-	-
HPADDANE_00016	5.57e-161	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Rhomboid family
HPADDANE_00017	3.51e-105	crgA	-	-	D	-	-	-	Involved in cell division
HPADDANE_00018	2.88e-150	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
HPADDANE_00019	8.7e-297	srtB	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
HPADDANE_00020	7.5e-153	trpG	2.6.1.85, 4.1.3.27	-	EH	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	para-aminobenzoate synthase glutamine amidotransferase component II
HPADDANE_00021	0.0	pknB	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
HPADDANE_00022	3.11e-221	pknA	2.7.11.1	-	T	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
HPADDANE_00023	0.0	pbpA	-	-	M	ko:K05364	ko00550,map00550	ko00000,ko00001,ko01011	penicillin-binding protein
HPADDANE_00024	0.0	rodA	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HPADDANE_00025	0.0	pstP	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	Sigma factor PP2C-like phosphatases
HPADDANE_00026	3.01e-83	fhaB	-	-	T	-	-	-	Inner membrane component of T3SS, cytoplasmic domain
HPADDANE_00027	2.49e-165	fhaA	-	-	T	-	-	-	Protein of unknown function (DUF2662)
HPADDANE_00028	0.0	pepX	3.4.14.5	-	E	ko:K01278	ko04974,map04974	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	Dipeptidyl peptidase IV (DPP IV) N-terminal region
HPADDANE_00029	5.05e-261	pldB	3.1.1.5	-	I	ko:K01048	ko00564,map00564	ko00000,ko00001,ko01000	Serine aminopeptidase, S33
HPADDANE_00030	5.99e-188	-	-	-	EG	-	-	-	EamA-like transporter family
HPADDANE_00031	6.57e-289	-	-	-	S	-	-	-	Putative esterase
HPADDANE_00032	0.0	lysX	-	-	S	-	-	-	Uncharacterised conserved protein (DUF2156)
HPADDANE_00033	8.7e-230	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HPADDANE_00034	5.55e-143	-	-	-	S	ko:K07005	-	ko00000	Pyridoxamine 5'-phosphate oxidase
HPADDANE_00035	1.09e-77	-	-	-	S	-	-	-	Domain of unknown function (DUF4928)
HPADDANE_00037	3.14e-208	-	2.1.1.37	-	L	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
HPADDANE_00038	8.33e-68	-	-	-	S	-	-	-	Putative heavy-metal-binding
HPADDANE_00039	2.2e-163	-	-	-	S	ko:K11068	-	ko00000,ko02042	Haemolysin-III related
HPADDANE_00040	1.7e-84	-	-	-	O	-	-	-	Hsp20/alpha crystallin family
HPADDANE_00041	1.06e-70	-	-	-	S	-	-	-	PfpI family
HPADDANE_00043	1.89e-41	-	-	-	T	-	-	-	Toxic component of a toxin-antitoxin (TA) module
HPADDANE_00046	3.87e-34	-	-	-	L	-	-	-	Transposase DDE domain
HPADDANE_00048	0.0	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HPADDANE_00049	0.0	degP	-	-	O	ko:K08372	ko02020,map02020	ko00000,ko00001,ko01000,ko01002	Domain present in PSD-95, Dlg, and ZO-1/2.
HPADDANE_00050	0.0	-	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
HPADDANE_00051	1.6e-246	urtA	-	-	E	ko:K11959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
HPADDANE_00052	2.2e-158	urtB	-	-	U	ko:K11960	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
HPADDANE_00053	1.34e-203	urtC	-	-	U	ko:K01998,ko:K11961	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
HPADDANE_00054	4.04e-147	urtD	-	-	S	ko:K11962	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid ATP-binding cassette transporter
HPADDANE_00055	5.88e-128	urtE	-	-	E	ko:K11963	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HPADDANE_00056	1.87e-138	hoxN	-	-	U	ko:K07241	-	ko00000,ko02000	Belongs to the NiCoT transporter (TC 2.A.52) family
HPADDANE_00057	6.14e-123	ureA	3.5.1.5	-	E	ko:K01430,ko:K14048	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	ko00000,ko00001,ko01000	Urease, gamma subunit
HPADDANE_00058	0.0	ureC	3.5.1.5	-	E	ko:K01427,ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	ko00000,ko00001,ko01000	Urease alpha-subunit, N-terminal domain
HPADDANE_00059	9.64e-113	ureE	-	-	O	ko:K03187	-	ko00000	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
HPADDANE_00060	5.59e-102	ureF	-	-	J	ko:K03188	-	ko00000	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
HPADDANE_00061	2.59e-127	ureG	-	-	KO	ko:K03189	-	ko00000	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HPADDANE_00062	9.01e-117	ureD	-	-	O	ko:K03190	-	ko00000	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
HPADDANE_00063	4.41e-125	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
HPADDANE_00064	1.33e-258	-	-	-	M	-	-	-	LPXTG cell wall anchor motif
HPADDANE_00065	1.57e-20	-	-	-	-	-	-	-	-
HPADDANE_00066	0.0	fprA	1.18.1.2, 1.19.1.1	-	C	ko:K00528	-	ko00000,ko01000	Pyridine nucleotide-disulphide oxidoreductase
HPADDANE_00067	1.18e-205	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
HPADDANE_00068	2.94e-127	-	3.2.1.4	GH5,GH9	S	ko:K01179,ko:K21449	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000,ko02000	acid phosphatase activity
HPADDANE_00070	1.11e-261	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HPADDANE_00071	6.04e-160	-	-	-	E	-	-	-	IrrE N-terminal-like domain
HPADDANE_00072	4.43e-93	-	-	-	S	-	-	-	Domain of unknown function (DUF4411)
HPADDANE_00073	4.2e-21	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
HPADDANE_00074	1.89e-30	-	-	-	K	ko:K03710	-	ko00000,ko03000	Transcriptional regulator
HPADDANE_00075	5.38e-177	-	-	-	O	-	-	-	ADP-ribosylglycohydrolase
HPADDANE_00076	2.68e-123	-	-	-	G	-	-	-	pfkB family carbohydrate kinase
HPADDANE_00077	6.04e-316	-	-	-	U	ko:K03457	-	ko00000	Permease for cytosine/purines, uracil, thiamine, allantoin
HPADDANE_00078	5.64e-107	-	-	-	Q	-	-	-	Isochorismatase family
HPADDANE_00079	1.42e-37	-	-	-	L	-	-	-	Transposase DDE domain
HPADDANE_00080	1.72e-153	mug	3.2.2.28	-	L	ko:K03649	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil DNA glycosylase superfamily
HPADDANE_00081	1.15e-262	fbaA	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
HPADDANE_00082	9.84e-07	-	-	-	S	-	-	-	AAA ATPase domain
HPADDANE_00084	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HPADDANE_00085	0.0	-	-	-	P	ko:K03281	-	ko00000	Voltage gated chloride channel
HPADDANE_00086	2.33e-199	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HPADDANE_00087	5.18e-81	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HPADDANE_00088	1.19e-259	-	-	-	K	ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HPADDANE_00089	0.0	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Domain of unknown function (DUF1964)
HPADDANE_00090	0.0	scrT	-	-	G	-	-	-	Transporter major facilitator family protein
HPADDANE_00091	0.0	-	-	-	EGP	-	-	-	Sugar (and other) transporter
HPADDANE_00092	2.4e-258	ilvC	1.1.1.86	-	H	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HPADDANE_00093	2.71e-66	bioN	-	-	P	ko:K16783	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HPADDANE_00094	4.04e-91	bioM	-	-	P	ko:K16784	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HPADDANE_00095	1.09e-74	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
HPADDANE_00096	1.45e-259	ilvC	1.1.1.86	-	H	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HPADDANE_00097	0.0	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha-amylase domain
HPADDANE_00098	3.85e-236	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HPADDANE_00099	0.0	malQ	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	4-alpha-glucanotransferase
HPADDANE_00100	0.0	strK	3.1.3.1, 3.1.3.39	-	P	ko:K01077,ko:K04342	ko00521,ko00730,ko00790,ko01100,ko01130,ko02020,map00521,map00730,map00790,map01100,map01130,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Alkaline phosphatase homologues
HPADDANE_00101	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HPADDANE_00102	2.8e-95	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HPADDANE_00103	3.79e-231	dnaJ	-	-	O	ko:K03686,ko:K05516	-	ko00000,ko03029,ko03036,ko03110	DnaJ molecular chaperone homology domain
HPADDANE_00104	5.09e-128	hspR	-	-	K	ko:K13640	-	ko00000,ko03000	transcriptional regulator, MerR family
HPADDANE_00105	1.17e-269	-	-	-	F	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HPADDANE_00106	6.13e-263	-	-	-	H	-	-	-	long-chain-fatty-acid--luciferin-component ligase, acyl-protein synthase
HPADDANE_00107	2.75e-290	-	-	-	C	-	-	-	Acyl-CoA reductase (LuxC)
HPADDANE_00108	1.08e-179	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
HPADDANE_00109	2.06e-159	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant 3
HPADDANE_00110	2.59e-171	dedA1	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
HPADDANE_00111	1.26e-120	-	-	-	D	-	-	-	bacterial-type flagellum organization
HPADDANE_00112	6.77e-247	cpaF	-	-	U	ko:K02283	-	ko00000,ko02035,ko02044	Type II IV secretion system protein
HPADDANE_00113	9.92e-135	-	-	-	U	ko:K12510	-	ko00000,ko02044	Type ii secretion system
HPADDANE_00114	1.57e-129	-	-	-	NU	-	-	-	Type II secretion system (T2SS), protein F
HPADDANE_00115	3.54e-53	-	-	-	S	-	-	-	Protein of unknown function (DUF4244)
HPADDANE_00116	1.27e-69	-	-	-	S	-	-	-	TIGRFAM helicase secretion neighborhood TadE-like protein
HPADDANE_00117	1.73e-271	-	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Diacylglycerol kinase catalytic domain protein
HPADDANE_00118	9.91e-137	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HPADDANE_00119	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III subunit gamma tau
HPADDANE_00120	1.93e-139	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HPADDANE_00121	3.41e-258	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
HPADDANE_00122	7.52e-65	-	-	-	S	ko:K07133	-	ko00000	Psort location Cytoplasmic, score
HPADDANE_00123	3.35e-169	ask	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
HPADDANE_00124	1.17e-125	ask	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	ACT domain
HPADDANE_00125	7.28e-267	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HPADDANE_00126	2.16e-148	-	-	-	-	-	-	-	-
HPADDANE_00127	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HPADDANE_00128	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HPADDANE_00129	0.0	pbp5	-	-	M	-	-	-	Transglycosylase
HPADDANE_00130	1.04e-211	-	-	-	I	-	-	-	PAP2 superfamily
HPADDANE_00131	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HPADDANE_00132	8.97e-159	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HPADDANE_00133	2.7e-258	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HPADDANE_00134	6.53e-131	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HPADDANE_00135	1.47e-50	hpr	-	-	G	ko:K11189	-	ko00000,ko02000	PTS HPr component phosphorylation site
HPADDANE_00137	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HPADDANE_00138	1.78e-136	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
HPADDANE_00139	0.0	pepD	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Peptidase family C69
HPADDANE_00140	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Formate-tetrahydrofolate ligase
HPADDANE_00141	5.49e-82	-	-	-	S	-	-	-	Macrophage migration inhibitory factor (MIF)
HPADDANE_00142	7.45e-124	-	-	-	S	-	-	-	GtrA-like protein
HPADDANE_00143	2.5e-255	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative DNA-binding domain
HPADDANE_00144	2.55e-297	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HPADDANE_00145	3.57e-158	-	-	-	G	-	-	-	Phosphoglycerate mutase family
HPADDANE_00146	4.83e-202	-	-	-	-	-	-	-	-
HPADDANE_00147	3.36e-217	-	5.1.3.15	-	G	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Aldose 1-epimerase
HPADDANE_00148	2.09e-210	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
HPADDANE_00149	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
HPADDANE_00150	1.35e-211	-	-	-	V	-	-	-	Abi-like protein
HPADDANE_00151	2.93e-116	-	3.1.21.3	-	L	ko:K01154	-	ko00000,ko01000,ko02048	PFAM restriction modification system DNA specificity domain
HPADDANE_00152	6.94e-71	-	-	-	-	-	-	-	-
HPADDANE_00153	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	modification (methylase) protein of type I restriction-modification system K03427
HPADDANE_00154	0.0	gltX	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HPADDANE_00157	8.45e-101	-	-	-	-	-	-	-	-
HPADDANE_00158	7.75e-176	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
HPADDANE_00159	4.41e-57	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
HPADDANE_00161	0.0	-	-	-	-	-	-	-	-
HPADDANE_00162	0.0	-	-	-	P	ko:K07243	-	ko00000,ko02000	Iron permease FTR1 family
HPADDANE_00163	1.43e-154	-	-	-	P	ko:K07230	-	ko00000,ko02000	Fe2+ transport protein
HPADDANE_00164	2.03e-291	-	-	-	S	-	-	-	Predicted membrane protein (DUF2318)
HPADDANE_00165	1.66e-287	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HPADDANE_00166	1.49e-274	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HPADDANE_00167	4.85e-188	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HPADDANE_00168	9.42e-111	-	-	-	S	-	-	-	FMN_bind
HPADDANE_00169	4.04e-136	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.87
HPADDANE_00170	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
HPADDANE_00171	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
HPADDANE_00172	1.57e-298	-	-	-	S	-	-	-	Putative ABC-transporter type IV
HPADDANE_00173	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HPADDANE_00174	1.69e-175	pgl	3.1.1.31	-	G	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
HPADDANE_00175	9.76e-233	opcA	-	-	G	-	-	-	Glucose-6-phosphate dehydrogenase subunit
HPADDANE_00176	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HPADDANE_00178	3.19e-12	-	-	-	-	-	-	-	-
HPADDANE_00179	8.52e-16	-	-	-	-	-	-	-	-
HPADDANE_00180	0.0	-	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Peptidase family C69
HPADDANE_00181	6.69e-239	-	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	Glycosyltransferase like family 2
HPADDANE_00182	2.83e-156	icaR	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HPADDANE_00183	4.88e-222	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HPADDANE_00184	1.59e-304	amt	-	-	U	ko:K03320	-	ko00000,ko02000	Ammonium Transporter Family
HPADDANE_00185	7.34e-72	glnB	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Nitrogen regulatory protein P-II
HPADDANE_00186	0.0	glnD	2.7.7.59	-	O	ko:K00990	ko02020,map02020	ko00000,ko00001,ko01000	Nucleotidyltransferase domain
HPADDANE_00187	0.0	dinF	-	-	V	-	-	-	MatE
HPADDANE_00188	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HPADDANE_00189	0.0	murE	-	-	M	-	-	-	Domain of unknown function (DUF1727)
HPADDANE_00190	1.29e-180	cobQ2	-	-	S	ko:K07009	-	ko00000	CobB/CobQ-like glutamine amidotransferase domain
HPADDANE_00191	1.44e-52	-	-	-	S	-	-	-	granule-associated protein
HPADDANE_00192	0.0	-	-	-	S	ko:K03688	-	ko00000	ABC1 family
HPADDANE_00193	9.77e-171	-	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HPADDANE_00194	6.23e-243	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HPADDANE_00195	1.13e-63	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
HPADDANE_00196	4.24e-97	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
HPADDANE_00197	2.15e-48	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HPADDANE_00198	1.35e-91	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HPADDANE_00200	2.54e-51	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system
HPADDANE_00201	0.0	ptsP	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HPADDANE_00202	2.03e-165	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HPADDANE_00203	0.0	-	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
HPADDANE_00204	1.35e-56	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	Metal-sensitive transcriptional repressor
HPADDANE_00205	1.29e-279	rmuC	-	-	S	ko:K09760	-	ko00000	RmuC family
HPADDANE_00206	4.22e-127	pyrE1	-	-	F	-	-	-	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HPADDANE_00207	1.3e-205	trmH	2.1.1.34	-	J	ko:K00556	-	ko00000,ko01000,ko03016	RNA methyltransferase TrmH family
HPADDANE_00208	1.91e-234	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HPADDANE_00209	5.98e-67	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HPADDANE_00210	0.0	gatA	6.3.5.6, 6.3.5.7	-	F	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HPADDANE_00211	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HPADDANE_00212	1.95e-250	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HPADDANE_00213	2.66e-68	-	-	-	S	-	-	-	Protein of unknown function (DUF2469)
HPADDANE_00214	0.0	-	-	-	S	-	-	-	Histidine phosphatase superfamily (branch 2)
HPADDANE_00215	0.0	-	-	-	H	-	-	-	Flavin containing amine oxidoreductase
HPADDANE_00216	0.0	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HPADDANE_00217	4.64e-83	tyrA	5.4.99.5	-	E	ko:K04092	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Chorismate mutase type II
HPADDANE_00218	0.0	-	-	-	S	-	-	-	domain protein
HPADDANE_00219	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HPADDANE_00220	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HPADDANE_00221	9.81e-165	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HPADDANE_00222	1.14e-176	glnR	-	-	KT	-	-	-	Transcriptional regulatory protein, C terminal
HPADDANE_00223	4.37e-123	-	-	-	-	-	-	-	-
HPADDANE_00224	9.55e-127	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
HPADDANE_00225	9.28e-118	ppa	3.6.1.1	-	C	ko:K01507	ko00190,map00190	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HPADDANE_00226	0.0	glgE	2.4.99.16	GH13	G	ko:K16147	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
HPADDANE_00227	0.0	-	-	-	K	-	-	-	RNA polymerase II activating transcription factor binding
HPADDANE_00228	6.92e-83	-	-	-	S	ko:K06889	-	ko00000	Psort location Cytoplasmic, score 8.87
HPADDANE_00229	1.95e-21	-	-	-	L	-	-	-	Transposase DDE domain
HPADDANE_00231	7.52e-35	-	-	-	G	-	-	-	beta-galactosidase
HPADDANE_00233	1.04e-05	-	-	-	K	-	-	-	sequence-specific DNA binding
HPADDANE_00237	1.31e-23	-	-	-	O	-	-	-	COG0330 Membrane protease subunits, stomatin prohibitin homologs
HPADDANE_00242	1.65e-67	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
HPADDANE_00246	5.34e-40	-	-	-	V	-	-	-	HNH endonuclease
HPADDANE_00247	1.58e-54	-	-	-	A	ko:K13288	ko03008,map03008	ko00000,ko00001,ko01000,ko03009,ko03019	3'-to-5' exoribonuclease specific for small oligoribonucleotides
HPADDANE_00248	1.23e-53	-	-	-	S	-	-	-	Protein of unknwon function (DUF3310)
HPADDANE_00252	1.86e-11	-	-	-	-	-	-	-	-
HPADDANE_00255	1.35e-11	whiB	-	-	K	ko:K18955	-	ko00000,ko03000	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
HPADDANE_00260	2.49e-46	-	-	-	L	-	-	-	HNH endonuclease
HPADDANE_00261	9.42e-10	-	-	-	-	-	-	-	-
HPADDANE_00262	1.91e-301	-	-	-	S	-	-	-	Terminase
HPADDANE_00263	6.98e-217	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
HPADDANE_00264	2.64e-110	-	-	-	-	-	-	-	-
HPADDANE_00267	8.1e-189	-	-	-	V	-	-	-	Phage capsid family
HPADDANE_00269	1.63e-61	-	-	-	S	-	-	-	Phage protein Gp19/Gp15/Gp42
HPADDANE_00270	2.93e-39	-	-	-	-	-	-	-	-
HPADDANE_00273	5.43e-79	-	-	-	N	-	-	-	domain, Protein
HPADDANE_00274	3.79e-35	-	-	-	-	-	-	-	-
HPADDANE_00276	1.36e-93	-	-	-	NT	-	-	-	phage tail tape measure protein
HPADDANE_00277	7.4e-66	-	-	-	S	-	-	-	phage tail
HPADDANE_00278	9.69e-283	-	-	-	S	-	-	-	Prophage endopeptidase tail
HPADDANE_00281	1.99e-46	-	-	-	-	-	-	-	-
HPADDANE_00282	1.08e-159	-	-	-	-	-	-	-	-
HPADDANE_00283	3.86e-105	-	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	reverse transcriptase
HPADDANE_00284	0.000663	-	-	-	-	-	-	-	-
HPADDANE_00285	2.76e-25	-	-	-	-	-	-	-	-
HPADDANE_00286	4.98e-135	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HPADDANE_00287	3.98e-37	-	-	-	S	-	-	-	Putative phage holin Dp-1
HPADDANE_00288	2.45e-50	-	-	-	-	-	-	-	-
HPADDANE_00289	2.66e-57	-	-	-	S	ko:K09803	-	ko00000	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system
HPADDANE_00290	4e-127	-	-	-	L	-	-	-	Phage integrase family
HPADDANE_00293	1.13e-17	-	-	-	-	-	-	-	-
HPADDANE_00294	1.26e-31	-	-	-	S	ko:K09803	-	ko00000	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system
HPADDANE_00295	3.84e-261	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HPADDANE_00296	3.96e-185	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HPADDANE_00297	9.96e-40	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HPADDANE_00298	6.77e-99	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HPADDANE_00299	4.42e-186	atpH	-	-	C	ko:K02109,ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HPADDANE_00300	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HPADDANE_00301	9.04e-205	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HPADDANE_00302	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HPADDANE_00303	2.55e-65	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HPADDANE_00304	1.48e-173	nucS	-	-	L	ko:K07503	-	ko00000,ko01000	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
HPADDANE_00305	1.14e-205	-	5.2.1.8	-	M	ko:K01802	-	ko00000,ko01000	FKBP-type peptidyl-prolyl cis-trans isomerase
HPADDANE_00306	1.02e-237	-	-	-	-	-	-	-	-
HPADDANE_00307	1.76e-232	-	-	-	-	-	-	-	-
HPADDANE_00308	3.99e-212	ybbN	-	-	O	ko:K05838	-	ko00000,ko03110	Tetratricopeptide repeat
HPADDANE_00309	9.16e-151	-	-	-	S	-	-	-	CYTH
HPADDANE_00311	1.1e-81	psp1	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	Endoribonuclease L-PSP
HPADDANE_00312	3.84e-232	plsC2	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
HPADDANE_00313	1.96e-228	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
HPADDANE_00314	3.5e-292	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HPADDANE_00315	5.89e-275	-	-	-	P	ko:K02055	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HPADDANE_00316	8.68e-207	-	-	-	U	ko:K02054	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HPADDANE_00317	5.91e-165	-	-	-	U	ko:K02053	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HPADDANE_00318	1.08e-289	-	-	-	E	ko:K02052	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HPADDANE_00319	1.65e-226	-	-	-	S	-	-	-	CAAX protease self-immunity
HPADDANE_00320	6.51e-177	-	-	-	M	-	-	-	Mechanosensitive ion channel
HPADDANE_00321	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Fumarase C C-terminus
HPADDANE_00322	1.56e-173	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HPADDANE_00323	3.11e-307	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HPADDANE_00324	1.86e-110	ogt	2.1.1.63	-	L	ko:K00567,ko:K07443	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HPADDANE_00325	3.38e-15	-	-	-	S	ko:K19784	-	ko00000	NADPH-dependent FMN reductase
HPADDANE_00331	1.21e-245	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HPADDANE_00332	1.39e-295	-	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
HPADDANE_00333	1.54e-248	-	-	-	G	-	-	-	pfkB family carbohydrate kinase
HPADDANE_00334	3.03e-40	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L28 family
HPADDANE_00335	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	helicase superfamily c-terminal domain
HPADDANE_00336	5.77e-130	steT	-	-	E	ko:K03294	-	ko00000	amino acid
HPADDANE_00338	6.2e-250	-	-	-	-	-	-	-	-
HPADDANE_00339	6.03e-238	-	-	-	U	ko:K06956	-	ko00000	Sodium:dicarboxylate symporter family
HPADDANE_00340	3.17e-135	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Conserved hypothetical protein 95
HPADDANE_00341	4.51e-196	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
HPADDANE_00342	0.0	-	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase family U32 C-terminal domain
HPADDANE_00343	1.69e-230	yfiH	-	-	Q	ko:K05810	-	ko00000,ko01000	Multi-copper polyphenol oxidoreductase laccase
HPADDANE_00344	3.19e-206	ispD	1.1.1.405, 2.7.7.40, 2.7.7.60	-	I	ko:K00991,ko:K21681	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HPADDANE_00345	1.97e-158	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HPADDANE_00346	8.85e-156	-	-	-	D	-	-	-	nuclear chromosome segregation
HPADDANE_00347	0.0	pepC2	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HPADDANE_00348	1.27e-269	aroG	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HPADDANE_00349	1.57e-298	aroG	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HPADDANE_00350	2.02e-157	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HPADDANE_00351	2.91e-294	-	-	-	EGP	-	-	-	Sugar (and other) transporter
HPADDANE_00352	1.33e-258	phoR	2.7.13.3	-	T	ko:K07636,ko:K07768	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
HPADDANE_00353	1.68e-179	regX3	-	-	KT	ko:K07776	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
HPADDANE_00354	1.55e-238	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import
HPADDANE_00355	3.53e-207	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HPADDANE_00356	2.32e-215	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease
HPADDANE_00357	3.17e-190	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HPADDANE_00358	1.03e-121	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
HPADDANE_00359	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
HPADDANE_00360	3.81e-16	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
HPADDANE_00361	1.08e-122	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
HPADDANE_00362	5.35e-71	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
HPADDANE_00363	7.67e-24	-	-	-	-	-	-	-	-
HPADDANE_00364	4.97e-217	-	-	-	C	-	-	-	Oxidoreductase, aldo keto reductase family protein
HPADDANE_00365	3.03e-257	-	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
HPADDANE_00366	2.08e-153	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HPADDANE_00367	1.61e-176	-	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HPADDANE_00368	6.88e-152	-	-	-	U	ko:K02025,ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HPADDANE_00369	7.48e-143	-	-	-	U	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HPADDANE_00370	9.25e-277	-	-	-	-	-	-	-	-
HPADDANE_00371	3.61e-226	-	2.7.11.1	-	S	ko:K07154	-	ko00000,ko01000,ko01001,ko02048	Pfam:HipA_N
HPADDANE_00372	3.36e-61	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HPADDANE_00373	1.3e-139	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HPADDANE_00374	1.24e-47	-	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
HPADDANE_00375	1.66e-83	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
HPADDANE_00376	1.18e-179	pabC	2.6.1.42, 2.6.1.85, 4.1.3.38	-	E	ko:K00826,ko:K01665,ko:K02619,ko:K03342	ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	branched-chain-amino-acid transaminase activity
HPADDANE_00377	0.0	pabB	2.6.1.85, 4.1.3.27, 4.1.3.38	-	EH	ko:K01657,ko:K01665,ko:K03342,ko:K13950	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000,ko01007	chorismate binding enzyme
HPADDANE_00378	1.53e-269	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HPADDANE_00379	4.86e-142	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Lumazine binding domain
HPADDANE_00380	3.15e-298	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HPADDANE_00381	3.04e-105	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HPADDANE_00382	1.91e-228	-	-	-	S	-	-	-	Endonuclease/Exonuclease/phosphatase family
HPADDANE_00383	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HPADDANE_00384	2.72e-208	-	-	-	P	-	-	-	Cation efflux family
HPADDANE_00385	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HPADDANE_00386	1.31e-175	-	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Peptidase C26
HPADDANE_00387	0.0	yjjK	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter
HPADDANE_00388	6.59e-81	vapC	-	-	S	ko:K07062	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module. An RNase
HPADDANE_00389	3.74e-58	-	-	-	S	ko:K21495	-	ko00000,ko02048	Plasmid stability protein
HPADDANE_00390	5.15e-118	ilvN	2.2.1.6	-	E	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	ACT domain
HPADDANE_00391	0.0	ilvB	2.2.1.6	-	H	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Thiamine pyrophosphate enzyme, central domain
HPADDANE_00392	6.33e-168	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HPADDANE_00393	3.14e-42	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
HPADDANE_00394	8.82e-154	-	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
HPADDANE_00395	4.92e-176	-	-	-	-	-	-	-	-
HPADDANE_00396	2.45e-114	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HPADDANE_00397	3.9e-69	-	-	-	S	-	-	-	Protein of unknown function (DUF3039)
HPADDANE_00398	6.01e-245	-	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo/keto reductase family
HPADDANE_00399	7.11e-91	-	-	-	K	-	-	-	MerR, DNA binding
HPADDANE_00400	2.95e-147	-	-	-	-	-	-	-	-
HPADDANE_00401	9.45e-317	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HPADDANE_00402	7.86e-206	-	-	-	-	-	-	-	-
HPADDANE_00403	2.22e-185	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HPADDANE_00404	7.06e-170	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HPADDANE_00406	1.53e-286	-	-	-	V	ko:K12554	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Psort location Cytoplasmic, score 8.87
HPADDANE_00407	9.35e-311	-	-	-	V	ko:K12554	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Psort location Cytoplasmic, score 8.87
HPADDANE_00408	1.01e-309	-	-	-	V	ko:K12554	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Psort location Cytoplasmic, score 8.87
HPADDANE_00409	2.24e-218	-	-	-	S	ko:K07088	-	ko00000	Auxin Efflux Carrier
HPADDANE_00412	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HPADDANE_00413	0.0	-	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HPADDANE_00414	0.0	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HPADDANE_00415	6.79e-79	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HPADDANE_00416	5.82e-187	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HPADDANE_00417	1.06e-188	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HPADDANE_00418	2.17e-267	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HPADDANE_00419	9.52e-116	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
HPADDANE_00420	1.88e-171	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
HPADDANE_00421	0.0	fadD	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
HPADDANE_00422	1.13e-29	araE	-	-	EGP	ko:K02100	-	ko00000,ko02000	Major facilitator Superfamily
HPADDANE_00423	1.4e-146	-	-	-	V	ko:K06147,ko:K06148,ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter transmembrane region
HPADDANE_00424	1.02e-310	-	-	-	U	ko:K02100	-	ko00000,ko02000	Sugar (and other) transporter
HPADDANE_00425	1.46e-126	-	-	-	T	-	-	-	Histidine kinase
HPADDANE_00426	2.34e-34	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
HPADDANE_00427	1.95e-26	-	-	-	S	-	-	-	Bacteriocin (Lactococcin_972)
HPADDANE_00428	1.43e-301	-	-	-	-	-	-	-	-
HPADDANE_00429	3.09e-130	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HPADDANE_00431	1.34e-30	-	-	-	L	-	-	-	Transposase
HPADDANE_00433	4.02e-219	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HPADDANE_00434	9.55e-106	galA	3.2.1.89	-	G	ko:K01224	-	ko00000,ko01000	Glycosyl hydrolase family 53
HPADDANE_00435	1.14e-149	-	-	-	S	-	-	-	Oxidoreductase, aldo keto reductase family protein
HPADDANE_00436	1.23e-172	-	-	-	L	-	-	-	Protein of unknown function (DUF1524)
HPADDANE_00437	5.14e-280	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HPADDANE_00438	0.0	-	-	-	U	-	-	-	Drug resistance MFS transporter, drug H antiporter-2 family
HPADDANE_00439	6.46e-22	-	-	-	S	-	-	-	AAA ATPase domain
HPADDANE_00440	8.24e-123	-	-	-	S	-	-	-	AAA ATPase domain
HPADDANE_00441	3.82e-126	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 7.50
HPADDANE_00443	3.07e-192	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
HPADDANE_00444	1.46e-106	intA	-	-	L	-	-	-	Phage integrase family
HPADDANE_00445	2.13e-26	-	-	-	-	-	-	-	-
HPADDANE_00447	2.76e-15	intA	-	-	L	-	-	-	Phage integrase family
HPADDANE_00449	4.36e-15	-	-	-	-	-	-	-	-
HPADDANE_00450	1.01e-142	-	-	-	-	-	-	-	-
HPADDANE_00451	1.48e-163	-	-	-	-	-	-	-	-
HPADDANE_00452	5.59e-99	-	-	-	L	-	-	-	Transposase
HPADDANE_00453	1.42e-94	-	-	-	L	-	-	-	Transposase
HPADDANE_00454	1.87e-164	-	-	-	S	ko:K11939	-	ko00000,ko02000	EamA-like transporter family
HPADDANE_00455	3.35e-50	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
HPADDANE_00456	3.56e-303	-	-	-	L	-	-	-	PFAM Integrase catalytic
HPADDANE_00457	1.98e-181	-	-	-	L	-	-	-	IstB-like ATP binding protein
HPADDANE_00458	4.55e-196	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
HPADDANE_00459	2.99e-06	-	-	-	-	-	-	-	-
HPADDANE_00460	3.95e-99	-	-	-	L	-	-	-	Transposase
HPADDANE_00461	6.39e-98	-	-	-	L	-	-	-	Transposase
HPADDANE_00462	1.63e-138	-	-	-	K	-	-	-	COG COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HPADDANE_00463	4.66e-147	-	-	-	T	-	-	-	Histidine kinase
HPADDANE_00464	6.69e-142	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HPADDANE_00465	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HPADDANE_00466	4.47e-36	-	-	-	K	ko:K03088	-	ko00000,ko03021	Psort location Cytoplasmic, score
HPADDANE_00467	9.14e-263	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
HPADDANE_00470	8.44e-41	-	-	-	-	-	-	-	-
HPADDANE_00471	0.0	intA	-	-	L	-	-	-	Phage integrase family
HPADDANE_00473	5.68e-138	-	-	-	S	-	-	-	Domain of unknown function (DUF4192)
HPADDANE_00474	0.0	-	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	ParB-like nuclease domain
HPADDANE_00475	1.24e-59	-	-	-	-	-	-	-	-
HPADDANE_00476	2.87e-76	-	-	-	-	-	-	-	-
HPADDANE_00477	4.22e-86	-	-	-	S	-	-	-	Bacterial mobilisation protein (MobC)
HPADDANE_00478	0.0	-	-	-	U	-	-	-	Relaxase/Mobilisation nuclease domain
HPADDANE_00479	3.37e-191	-	-	-	S	-	-	-	Protein of unknown function (DUF3801)
HPADDANE_00480	2.09e-91	-	-	-	-	-	-	-	-
HPADDANE_00481	5.64e-112	-	-	-	S	-	-	-	Antirestriction protein (ArdA)
HPADDANE_00482	5.19e-147	-	-	-	S	-	-	-	Antirestriction protein (ArdA)
HPADDANE_00483	1.78e-67	-	-	-	-	-	-	-	-
HPADDANE_00485	0.0	-	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	Type IV secretory system Conjugative DNA transfer
HPADDANE_00487	1.18e-106	-	-	-	M	-	-	-	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HPADDANE_00489	2.81e-60	-	-	-	P	-	-	-	Major facilitator superfamily
HPADDANE_00490	8.85e-109	-	-	-	V	-	-	-	Abi-like protein
HPADDANE_00491	9.26e-45	-	-	-	-	-	-	-	-
HPADDANE_00493	1.2e-21	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HPADDANE_00495	1.8e-236	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Divergent AAA domain protein
HPADDANE_00496	1.07e-11	-	-	-	-	-	-	-	-
HPADDANE_00497	1.24e-297	intA	-	-	L	-	-	-	Phage integrase family
HPADDANE_00498	1.44e-93	-	-	-	-	-	-	-	-
HPADDANE_00501	4.94e-220	intA	-	-	L	-	-	-	Phage integrase family
HPADDANE_00502	8.23e-41	-	-	-	G	-	-	-	Glycosyl hydrolase family 20, domain 2
HPADDANE_00503	8.95e-83	-	-	-	G	-	-	-	Glycosyl hydrolase family 20, domain 2
HPADDANE_00504	3.16e-262	-	-	-	G	-	-	-	Glycosyl hydrolase family 20, domain 2
HPADDANE_00505	9.01e-196	-	-	-	U	ko:K17331	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HPADDANE_00506	1.03e-179	-	-	-	U	ko:K17330	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HPADDANE_00507	1.53e-212	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HPADDANE_00508	5.39e-123	-	-	-	K	-	-	-	Bacterial regulatory proteins, luxR family
HPADDANE_00509	1.6e-248	-	-	-	T	-	-	-	Histidine kinase
HPADDANE_00510	3.68e-64	-	-	-	-	-	-	-	-
HPADDANE_00511	1.08e-87	-	-	-	-	-	-	-	-
HPADDANE_00512	1.13e-296	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Efflux ABC transporter, permease protein
HPADDANE_00513	9.25e-178	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HPADDANE_00514	1.46e-244	-	3.4.21.83	-	E	ko:K01354	ko05142,ko05143,map05142,map05143	ko00000,ko00001,ko01000,ko01002	Prolyl oligopeptidase family
HPADDANE_00515	1.36e-164	-	3.4.21.83	-	E	ko:K01354	ko05142,ko05143,map05142,map05143	ko00000,ko00001,ko01000,ko01002	Prolyl oligopeptidase family
HPADDANE_00517	3.65e-119	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
HPADDANE_00518	1.57e-214	tcsS2	-	-	T	-	-	-	Histidine kinase
HPADDANE_00519	2.12e-132	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HPADDANE_00520	1.58e-190	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HPADDANE_00521	1.73e-232	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HPADDANE_00522	2.93e-97	-	-	-	K	-	-	-	Bacterial regulatory proteins, luxR family
HPADDANE_00523	4.5e-61	-	-	-	T	-	-	-	Histidine kinase
HPADDANE_00524	9.14e-41	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	efflux transmembrane transporter activity
HPADDANE_00525	2.72e-92	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HPADDANE_00526	6.73e-141	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
HPADDANE_00527	2.87e-42	-	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HPADDANE_00528	0.0	-	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HPADDANE_00529	1.06e-24	-	-	-	-	-	-	-	-
HPADDANE_00530	7.71e-157	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HPADDANE_00531	4.97e-157	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
HPADDANE_00532	4.96e-95	-	-	-	T	-	-	-	Histidine kinase
HPADDANE_00533	1.49e-128	-	-	-	T	-	-	-	Histidine kinase
HPADDANE_00534	1.21e-23	-	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	Type IV secretory system Conjugative DNA transfer
HPADDANE_00536	1.04e-153	-	-	-	V	ko:K01990,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
HPADDANE_00538	1.12e-74	-	-	-	-	-	-	-	-
HPADDANE_00539	4.34e-117	-	-	-	-	-	-	-	-
HPADDANE_00540	4.29e-91	-	-	-	-	-	-	-	-
HPADDANE_00541	5.27e-265	-	-	-	M	-	-	-	CHAP domain
HPADDANE_00542	0.0	-	-	-	U	-	-	-	type IV secretory pathway VirB4
HPADDANE_00543	1.77e-81	-	-	-	S	-	-	-	PrgI family protein
HPADDANE_00544	8.85e-183	-	-	-	-	-	-	-	-
HPADDANE_00545	1.44e-42	-	-	-	-	-	-	-	-
HPADDANE_00546	1.78e-57	-	-	-	-	-	-	-	-
HPADDANE_00547	1e-125	-	-	-	K	-	-	-	transcriptional regulator
HPADDANE_00548	1.1e-296	-	2.7.13.3	-	T	ko:K18351	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	GHKL domain
HPADDANE_00549	1.02e-153	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
HPADDANE_00550	1.03e-77	-	-	-	-	-	-	-	-
HPADDANE_00551	2.29e-154	-	-	-	-	-	-	-	-
HPADDANE_00552	1.35e-239	-	-	-	V	-	-	-	Putative peptidoglycan binding domain
HPADDANE_00553	6.87e-172	-	-	-	V	-	-	-	ABC transporter
HPADDANE_00554	4.57e-248	-	-	-	-	-	-	-	-
HPADDANE_00555	1.98e-125	-	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
HPADDANE_00557	8.73e-154	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HPADDANE_00558	3.3e-138	-	-	-	-	-	-	-	-
HPADDANE_00559	2.76e-104	-	-	-	-	-	-	-	-
HPADDANE_00560	4.24e-46	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPase activity
HPADDANE_00561	2.3e-56	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	PFAM ABC-2 type transporter
HPADDANE_00562	0.0	-	-	-	M	-	-	-	Cell surface antigen C-terminus
HPADDANE_00564	9.68e-163	-	-	-	K	-	-	-	Helix-turn-helix domain protein
HPADDANE_00565	1.73e-36	-	-	-	-	-	-	-	-
HPADDANE_00566	1.03e-91	-	-	-	-	-	-	-	-
HPADDANE_00567	5.82e-47	-	-	-	-	-	-	-	-
HPADDANE_00568	5.95e-133	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	AAA domain
HPADDANE_00569	3.71e-127	-	-	-	S	ko:K18955	-	ko00000,ko03000	Transcription factor WhiB
HPADDANE_00570	1.23e-294	-	-	-	S	-	-	-	Helix-turn-helix domain
HPADDANE_00571	3.18e-30	-	-	-	-	-	-	-	-
HPADDANE_00572	4.53e-16	-	-	-	-	-	-	-	-
HPADDANE_00574	8.11e-202	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HPADDANE_00575	5.63e-255	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HPADDANE_00578	0.0	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	Mycolic acid cyclopropane synthetase
HPADDANE_00579	1.17e-268	fucO	1.1.1.77, 1.1.99.37, 1.2.98.1	-	C	ko:K00048,ko:K17067	ko00625,ko00630,ko00640,ko00680,ko01120,ko01200,map00625,map00630,map00640,map00680,map01120,map01200	ko00000,ko00001,ko01000	Iron-containing alcohol dehydrogenase
HPADDANE_00580	9.38e-228	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HPADDANE_00581	0.0	-	-	-	S	-	-	-	AI-2E family transporter
HPADDANE_00582	1.38e-295	-	-	-	M	-	-	-	Glycosyl transferase family 21
HPADDANE_00583	1.77e-208	natA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HPADDANE_00584	0.0	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
HPADDANE_00585	0.0	dacB	3.4.16.4	-	M	ko:K07259	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	D-Ala-D-Ala carboxypeptidase 3 (S13) family
HPADDANE_00586	6.02e-269	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K00760,ko:K04075	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HPADDANE_00587	2.03e-124	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
HPADDANE_00588	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HPADDANE_00590	2.43e-137	folE	3.5.4.16	-	H	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase
HPADDANE_00591	1.28e-196	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HPADDANE_00592	0.0	folK	2.7.6.3, 4.1.2.25	-	H	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HPADDANE_00593	3.7e-118	-	-	-	S	-	-	-	Protein of unknown function (DUF3180)
HPADDANE_00594	1.04e-216	tesB	-	-	I	ko:K10805	ko01040,map01040	ko00000,ko00001,ko01000,ko01004	Thioesterase-like superfamily
HPADDANE_00595	0.0	yjjK	-	-	S	-	-	-	ATP-binding cassette protein, ChvD family
HPADDANE_00597	1.92e-264	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HPADDANE_00600	1.33e-49	-	-	-	L	-	-	-	Transposase, Mutator family
HPADDANE_00601	3.4e-120	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HPADDANE_00602	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HPADDANE_00603	8.16e-78	-	-	-	K	-	-	-	Virulence activator alpha C-term
HPADDANE_00605	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HPADDANE_00607	1.96e-224	glkA	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HPADDANE_00608	4.62e-82	-	-	-	EGP	-	-	-	Major facilitator superfamily
HPADDANE_00609	4.72e-206	dkg	-	-	S	-	-	-	Oxidoreductase, aldo keto reductase family protein
HPADDANE_00610	2.32e-90	fms	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
HPADDANE_00611	8.69e-187	-	-	-	-	-	-	-	-
HPADDANE_00612	2.75e-27	-	-	-	U	-	-	-	Drug resistance MFS transporter, drug H antiporter-2 family
HPADDANE_00613	1.06e-32	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HPADDANE_00614	4.72e-84	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
HPADDANE_00615	6.05e-291	xylR	-	-	GK	-	-	-	ROK family
HPADDANE_00617	6.44e-49	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the 23S rRNA
HPADDANE_00618	2.35e-246	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HPADDANE_00619	1.02e-199	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HPADDANE_00620	3.32e-265	-	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
HPADDANE_00621	1.71e-170	-	-	-	U	ko:K01997	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HPADDANE_00622	1.17e-217	-	-	-	U	ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HPADDANE_00623	1.82e-194	livG	-	-	E	ko:K01995	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid ATP-binding cassette transporter
HPADDANE_00624	1.08e-155	livF	-	-	E	ko:K01995,ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
HPADDANE_00625	6.04e-09	maa	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	O-acyltransferase activity
HPADDANE_00626	1.97e-153	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Belongs to the SUA5 family
HPADDANE_00627	1.65e-272	rfe	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	Glycosyl transferase family 4
HPADDANE_00628	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HPADDANE_00629	7.73e-147	orn	-	-	L	ko:K13288	ko03008,map03008	ko00000,ko00001,ko01000,ko03009,ko03019	3'-to-5' exoribonuclease specific for small oligoribonucleotides
HPADDANE_00630	0.0	-	-	-	L	-	-	-	PIF1-like helicase
HPADDANE_00631	4.76e-229	-	-	-	L	-	-	-	PFAM Integrase catalytic
HPADDANE_00632	6.59e-221	tnp7109-2	-	-	L	ko:K07493	-	ko00000	Transposase, Mutator family
HPADDANE_00633	6.56e-29	-	-	-	NU	-	-	-	Tfp pilus assembly protein FimV
HPADDANE_00634	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HPADDANE_00635	1.58e-68	ssb2	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-strand binding protein family
HPADDANE_00636	0.0	pepO	3.4.24.11, 3.4.24.71	-	O	ko:K01389,ko:K01415,ko:K07386	ko04614,ko04640,ko04974,ko05010,map04614,map04640,map04974,map05010	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	Peptidase family M13
HPADDANE_00637	7.06e-184	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
HPADDANE_00638	1.07e-193	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
HPADDANE_00639	3.02e-313	gltA	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Citrate synthase, C-terminal domain
HPADDANE_00640	1.42e-224	dapD	2.3.1.117	-	E	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
HPADDANE_00641	2.55e-270	-	-	-	K	-	-	-	WYL domain
HPADDANE_00642	0.0	-	-	-	KL	-	-	-	Psort location Cytoplasmic, score 8.87
HPADDANE_00643	2.65e-103	-	-	-	S	-	-	-	PFAM Uncharacterised protein family UPF0150
HPADDANE_00644	4.04e-46	-	-	-	-	-	-	-	-
HPADDANE_00645	1.16e-46	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HPADDANE_00646	1.92e-109	vsr	-	-	L	ko:K07458	-	ko00000,ko01000,ko03400	May nick specific sequences that contain T G mispairs resulting from m5C-deamination
HPADDANE_00647	9.73e-254	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HPADDANE_00648	2.79e-295	aspB	2.6.1.1, 2.6.1.2, 2.6.1.66	-	E	ko:K00812,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase class-V
HPADDANE_00649	3.24e-12	ppx1	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	Ppx/GppA phosphatase family
HPADDANE_00650	6.21e-246	-	-	-	S	ko:K18353	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01504	Endonuclease/Exonuclease/phosphatase family
HPADDANE_00652	8.33e-99	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
HPADDANE_00653	0.0	-	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
HPADDANE_00654	5.46e-115	ywrO	-	-	S	-	-	-	Flavodoxin-like fold
HPADDANE_00655	5.18e-296	-	-	-	S	-	-	-	peptidyl-serine autophosphorylation
HPADDANE_00656	7.8e-57	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HPADDANE_00657	0.0	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HPADDANE_00658	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Anaerobic ribonucleoside-triphosphate reductase
HPADDANE_00659	3.06e-184	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HPADDANE_00660	0.0	hgdC	-	-	I	-	-	-	CoA enzyme activase uncharacterised domain (DUF2229)
HPADDANE_00661	3e-95	-	-	-	L	ko:K07450	-	ko00000	Resolvase, N terminal domain
HPADDANE_00662	2.41e-250	-	-	-	L	ko:K07496	-	ko00000	Helix-turn-helix domain
HPADDANE_00663	0.0	egtA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Glutamate-cysteine ligase family 2(GCS2)
HPADDANE_00664	1.72e-62	bgl2	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Fibronectin type III-like domain
HPADDANE_00665	1.18e-60	-	-	-	S	-	-	-	Nucleotidyltransferase domain
HPADDANE_00666	8.9e-92	-	-	-	S	-	-	-	Nucleotidyltransferase substrate binding protein like
HPADDANE_00667	1.64e-309	-	3.2.1.4, 3.2.1.58	GH5,GH9	G	ko:K01179,ko:K01210	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 5 (cellulase A) family
HPADDANE_00668	2.5e-89	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HPADDANE_00669	0.0	bglB	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Glycosyl hydrolase family 3 N-terminal domain protein
HPADDANE_00670	0.0	-	5.1.3.2	-	GM	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	ADP-glyceromanno-heptose 6-epimerase activity
HPADDANE_00671	3.18e-208	-	-	-	-	-	-	-	-
HPADDANE_00672	0.0	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2194)
HPADDANE_00673	0.0	-	-	GT4	M	ko:K21011	ko02025,map02025	ko00000,ko00001,ko01003	Domain of unknown function (DUF3492)
HPADDANE_00674	0.0	-	-	-	S	ko:K21012	ko02025,map02025	ko00000,ko00001	Putative exopolysaccharide Exporter (EPS-E)
HPADDANE_00675	0.0	-	-	-	M	ko:K06330	-	ko00000	CotH kinase protein
HPADDANE_00676	6.19e-200	-	-	-	P	-	-	-	VTC domain
HPADDANE_00677	1.8e-143	-	-	-	S	-	-	-	Domain of unknown function (DUF4956)
HPADDANE_00678	0.0	-	3.1.4.52	-	T	ko:K14051	ko02024,ko02026,map02024,map02026	ko00000,ko00001,ko01000	Putative diguanylate phosphodiesterase
HPADDANE_00679	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HPADDANE_00680	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
HPADDANE_00681	7.25e-47	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HPADDANE_00682	1.29e-209	rihB	3.2.2.1, 3.2.2.8	-	F	ko:K01239,ko:K01250,ko:K10213	ko00230,ko00240,ko00760,ko01100,map00230,map00240,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
HPADDANE_00683	2.31e-241	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HPADDANE_00684	2.81e-204	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HPADDANE_00685	8.84e-222	-	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
HPADDANE_00686	1.33e-137	-	-	-	K	-	-	-	FCD
HPADDANE_00687	2.86e-181	-	-	-	L	-	-	-	Domain of unknown function (DUF4862)
HPADDANE_00688	7.52e-152	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HPADDANE_00689	1.59e-147	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HPADDANE_00690	0.0	neu	3.2.1.18	GH33	G	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	ko00000,ko00001,ko01000,ko02042	BNR repeat-like domain
HPADDANE_00691	0.0	oppA7	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HPADDANE_00692	9.16e-215	oppB6	-	-	EP	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HPADDANE_00693	0.0	oppCD2	-	-	EP	ko:K02031,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
HPADDANE_00694	5.48e-181	oppF	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
HPADDANE_00695	6.05e-206	nanA	4.1.3.3, 4.3.3.7	-	EM	ko:K01639,ko:K01714	ko00261,ko00300,ko00520,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map00520,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Dihydrodipicolinate synthetase family
HPADDANE_00696	9.15e-308	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I II
HPADDANE_00697	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HPADDANE_00698	1.28e-256	-	-	-	P	ko:K02055	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HPADDANE_00699	4.24e-195	-	-	-	U	ko:K02054	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HPADDANE_00700	9.99e-198	-	-	-	U	ko:K02053	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HPADDANE_00701	4.28e-254	-	-	-	E	ko:K02052	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HPADDANE_00702	4.03e-201	-	-	-	I	-	-	-	type I phosphodiesterase nucleotide pyrophosphatase
HPADDANE_00703	2.28e-58	-	-	-	L	-	-	-	Transposase, Mutator family
HPADDANE_00704	4.87e-82	-	-	-	L	-	-	-	PFAM Integrase catalytic
HPADDANE_00705	5.33e-16	-	-	-	L	-	-	-	Helix-turn-helix domain
HPADDANE_00706	3.33e-219	uxuT	-	-	G	ko:K03292,ko:K16210	-	ko00000,ko02000	MFS/sugar transport protein
HPADDANE_00707	6.46e-27	-	-	-	G	ko:K16210	-	ko00000,ko02000	MFS/sugar transport protein
HPADDANE_00709	9.21e-58	-	-	-	G	ko:K16210	-	ko00000,ko02000	MFS/sugar transport protein
HPADDANE_00710	6.63e-68	-	-	-	K	ko:K02529,ko:K05499	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HPADDANE_00711	4.05e-89	-	-	-	K	ko:K02529,ko:K05499	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
HPADDANE_00712	6.66e-288	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HPADDANE_00713	1.82e-295	-	4.2.1.8	-	M	ko:K08323	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	mandelate racemase muconate lactonizing
HPADDANE_00714	5.93e-242	mtlD	1.1.1.57, 1.1.1.58	-	G	ko:K00040,ko:K00041	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Mannitol dehydrogenase C-terminal domain
HPADDANE_00715	3.48e-218	uxaC	5.3.1.12	-	G	ko:K01812	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Glucuronate isomerase
HPADDANE_00716	2.76e-68	-	-	-	FG	-	-	-	bis(5'-adenosyl)-triphosphatase activity
HPADDANE_00717	7.6e-53	-	-	-	L	ko:K07483	-	ko00000	Psort location Cytoplasmic, score 8.87
HPADDANE_00718	2.33e-49	-	-	-	L	ko:K07483	-	ko00000	Integrase core domain
HPADDANE_00719	0.0	-	-	-	L	-	-	-	PFAM Integrase catalytic
HPADDANE_00720	2.38e-77	-	-	-	-	-	-	-	-
HPADDANE_00721	3.25e-09	etp	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Low molecular weight phosphatase family
HPADDANE_00722	2.34e-42	-	-	-	-	-	-	-	-
HPADDANE_00723	2.68e-29	-	-	-	L	-	-	-	HTH-like domain
HPADDANE_00724	3.31e-57	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Belongs to the bacterial histone-like protein family
HPADDANE_00725	0.0	-	-	-	S	-	-	-	Lysylphosphatidylglycerol synthase TM region
HPADDANE_00726	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Adenylosuccinate lyase C-terminal
HPADDANE_00727	0.0	-	-	-	S	-	-	-	PGAP1-like protein
HPADDANE_00728	3.14e-68	-	-	-	-	-	-	-	-
HPADDANE_00729	1.49e-80	-	-	-	-	-	-	-	-
HPADDANE_00730	4.54e-223	-	-	-	S	ko:K07114	-	ko00000,ko02000	von Willebrand factor (vWF) type A domain
HPADDANE_00731	1.06e-237	-	-	-	S	ko:K07114	-	ko00000,ko02000	von Willebrand factor (vWF) type A domain
HPADDANE_00732	7.42e-117	-	-	-	-	-	-	-	-
HPADDANE_00733	7.32e-220	-	-	-	S	-	-	-	Protein of unknown function DUF58
HPADDANE_00734	1.86e-246	moxR	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
HPADDANE_00735	6.65e-168	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HPADDANE_00736	2.34e-99	-	-	-	S	-	-	-	LytR cell envelope-related transcriptional attenuator
HPADDANE_00737	2.18e-51	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
HPADDANE_00738	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HPADDANE_00739	2.78e-55	-	-	-	S	-	-	-	Proteins of 100 residues with WXG
HPADDANE_00740	2.16e-112	-	-	-	-	-	-	-	-
HPADDANE_00741	2.26e-170	phoP	-	-	KT	ko:K02483	-	ko00000,ko02022	Response regulator receiver domain protein
HPADDANE_00742	0.0	phoR	2.7.13.3	-	T	ko:K02484	-	ko00000,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HPADDANE_00743	1.01e-86	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
HPADDANE_00744	3.16e-247	-	-	-	S	-	-	-	Protein of unknown function (DUF3027)
HPADDANE_00745	3.37e-223	uspA	-	-	T	-	-	-	Belongs to the universal stress protein A family
HPADDANE_00746	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	ATPase family associated with various cellular activities (AAA)
HPADDANE_00747	0.0	-	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	5'-nucleotidase, C-terminal domain
HPADDANE_00748	2.57e-316	-	-	-	S	-	-	-	Domain of Unknown Function (DUF349)
HPADDANE_00749	0.0	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Histidyl-tRNA synthetase
HPADDANE_00750	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HPADDANE_00751	2.06e-231	-	-	-	S	-	-	-	Protein of unknown function (DUF559)
HPADDANE_00752	1.93e-181	gluA	-	-	E	ko:K10008	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding protein of ABC transporter for glutamate K02028
HPADDANE_00753	3.42e-195	gluB	-	-	ET	ko:K10005	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
HPADDANE_00754	3.05e-137	gluC	-	-	E	ko:K10006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HPADDANE_00755	2.57e-236	gluD	-	-	E	ko:K10007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HPADDANE_00756	0.0	-	-	-	I	-	-	-	PAP2 superfamily
HPADDANE_00757	3.92e-247	-	-	-	S	-	-	-	Polyphosphate kinase 2 (PPK2)
HPADDANE_00758	0.0	-	-	-	L	-	-	-	DEAD DEAH box helicase
HPADDANE_00759	1.92e-314	rarA	-	-	L	ko:K07478	-	ko00000	Recombination factor protein RarA
HPADDANE_00760	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HPADDANE_00761	9.11e-236	-	-	-	EH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HPADDANE_00762	1.36e-112	-	-	-	J	-	-	-	TM2 domain
HPADDANE_00763	8.24e-71	-	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
HPADDANE_00764	3.84e-62	-	-	-	J	ko:K07574	-	ko00000,ko03009	CRS1_YhbY
HPADDANE_00765	0.0	-	-	-	GP	ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HPADDANE_00766	8.23e-138	-	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HPADDANE_00767	2.13e-256	-	-	-	S	-	-	-	Glycosyltransferase, group 2 family protein
HPADDANE_00768	6.61e-181	ppgK	2.7.1.2, 2.7.1.63	-	GK	ko:K00845,ko:K00886	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HPADDANE_00769	4.76e-289	-	-	-	E	-	-	-	Aminotransferase class I and II
HPADDANE_00770	5.69e-177	-	-	-	P	ko:K16784	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HPADDANE_00771	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HPADDANE_00772	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
HPADDANE_00773	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HPADDANE_00774	9.47e-260	mrp	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HPADDANE_00775	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 20, domain 2
HPADDANE_00776	1.33e-163	-	-	-	V	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
HPADDANE_00777	4.16e-143	-	-	-	V	ko:K02068	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HPADDANE_00778	7.09e-136	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HPADDANE_00779	1.72e-122	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HPADDANE_00780	4.98e-302	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
HPADDANE_00781	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase large chain, oligomerisation domain
HPADDANE_00782	5.99e-214	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HPADDANE_00783	4.38e-134	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HPADDANE_00784	4.49e-169	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Exonuclease, DNA polymerase III, epsilon subunit family
HPADDANE_00785	0.0	tetM	-	-	J	ko:K18220	-	br01600,ko00000,ko01504	Elongation factor G, domain IV
HPADDANE_00786	2.33e-157	-	-	-	S	ko:K06999	-	ko00000	Phospholipase/Carboxylesterase
HPADDANE_00787	2.04e-125	glnP2	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HPADDANE_00788	6.49e-143	glnP	-	-	E	ko:K02029,ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HPADDANE_00789	3.79e-145	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ATP binding protein of ABC transporter for glutamate aspartate K02028
HPADDANE_00790	1.1e-165	glnH	-	-	ET	ko:K02030,ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
HPADDANE_00791	1.16e-284	metC1	4.4.1.8	-	E	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
HPADDANE_00792	2.28e-57	-	-	-	O	-	-	-	Glutaredoxin
HPADDANE_00793	1.92e-197	-	-	-	E	-	-	-	Glyoxalase-like domain
HPADDANE_00794	1.33e-186	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HPADDANE_00795	2.13e-255	-	4.1.1.37	-	H	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen decarboxylase (URO-D)
HPADDANE_00796	1.19e-279	-	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
HPADDANE_00797	0.0	-	-	-	E	ko:K01997,ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
HPADDANE_00798	0.0	-	-	-	E	ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
HPADDANE_00799	1.22e-290	-	-	-	S	ko:K01436	-	ko00000,ko01000,ko01002	Peptidase dimerisation domain
HPADDANE_00800	1e-307	-	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Cys/Met metabolism PLP-dependent enzyme
HPADDANE_00801	1.19e-177	ehuA	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HPADDANE_00802	6.29e-182	-	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Bacterial periplasmic substrate-binding proteins
HPADDANE_00803	2.37e-143	tcyA/tcyB	-	-	E	ko:K02029,ko:K02424,ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Binding-protein-dependent transport system inner membrane component
HPADDANE_00804	4.52e-170	hflK	-	-	O	-	-	-	prohibitin homologues
HPADDANE_00805	1.4e-200	-	-	-	S	-	-	-	Patatin-like phospholipase
HPADDANE_00806	4.68e-190	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HPADDANE_00807	3.73e-208	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
HPADDANE_00808	3.63e-164	-	-	-	S	-	-	-	Vitamin K epoxide reductase
HPADDANE_00809	2.1e-214	PPA1328	3.1.3.97, 3.1.4.57	-	S	ko:K07053,ko:K20859	ko00440,map00440	ko00000,ko00001,ko01000	DNA polymerase alpha chain like domain
HPADDANE_00810	1.13e-44	-	-	-	S	-	-	-	Protein of unknown function (DUF3107)
HPADDANE_00811	0.0	mphA	-	-	S	-	-	-	Aminoglycoside phosphotransferase
HPADDANE_00812	0.0	uvrD2	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HPADDANE_00813	0.0	-	-	-	S	-	-	-	Zincin-like metallopeptidase
HPADDANE_00814	1.19e-202	sdrC	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
HPADDANE_00815	2.15e-65	-	-	-	S	-	-	-	Protein of unknown function (DUF3052)
HPADDANE_00817	0.0	-	-	-	NU	-	-	-	Tfp pilus assembly protein FimV
HPADDANE_00818	1.28e-274	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HPADDANE_00819	6.58e-294	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HPADDANE_00820	0.0	-	-	-	I	-	-	-	acetylesterase activity
HPADDANE_00821	5.21e-145	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
HPADDANE_00822	1.3e-195	uppS	2.5.1.31, 2.5.1.86, 2.5.1.88	-	H	ko:K00806,ko:K14215,ko:K21273	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HPADDANE_00823	1.12e-264	-	-	-	F	-	-	-	nucleoside hydrolase
HPADDANE_00824	3.84e-258	-	-	-	P	-	-	-	NMT1/THI5 like
HPADDANE_00825	1.32e-178	-	-	-	P	-	-	-	Binding-protein-dependent transport system inner membrane component
HPADDANE_00826	0.0	fosC	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
HPADDANE_00827	1.8e-306	lacY	-	-	P	ko:K02532	-	ko00000,ko02000	LacY proton/sugar symporter
HPADDANE_00828	4.09e-153	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HPADDANE_00829	3.55e-68	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HPADDANE_00830	0.0	-	-	-	O	ko:K13963	ko05146,map05146	ko00000,ko00001	SERine Proteinase INhibitors
HPADDANE_00831	2.35e-23	-	-	-	-	-	-	-	-
HPADDANE_00832	6.69e-81	-	-	-	S	-	-	-	Thiamine-binding protein
HPADDANE_00833	3.04e-187	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HPADDANE_00834	2.27e-289	-	-	-	O	ko:K13525	ko04141,ko05134,map04141,map05134	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	AAA domain (Cdc48 subfamily)
HPADDANE_00835	0.0	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HPADDANE_00836	2.62e-212	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HPADDANE_00837	0.0	glyQS	6.1.1.14	-	J	ko:K01880	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of glycine to tRNA(Gly)
HPADDANE_00838	1.08e-304	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HPADDANE_00839	6.78e-256	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HPADDANE_00840	2.78e-103	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HPADDANE_00841	2.24e-56	-	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
HPADDANE_00842	8.57e-137	-	-	-	V	-	-	-	DivIVA protein
HPADDANE_00843	2.1e-116	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HPADDANE_00844	2.49e-229	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HPADDANE_00845	7.87e-166	-	-	-	S	ko:K07058	-	ko00000	Virulence factor BrkB
HPADDANE_00846	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III alpha subunit
HPADDANE_00847	9.06e-99	-	-	-	S	-	-	-	Domain of unknown function (DUF4186)
HPADDANE_00848	0.0	-	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	MCRA family
HPADDANE_00849	2.68e-37	-	-	-	S	-	-	-	Unextendable partial coding region
HPADDANE_00850	2.15e-196	-	-	-	S	-	-	-	Aldo/keto reductase family
HPADDANE_00851	1.25e-242	-	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	FGGY family of carbohydrate kinases, N-terminal domain
HPADDANE_00852	1.51e-68	-	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	FGGY family of carbohydrate kinases, N-terminal domain
HPADDANE_00853	0.0	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HPADDANE_00854	4.49e-279	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HPADDANE_00855	4.75e-144	hisB	3.1.3.15, 4.2.1.19	-	E	ko:K01089,ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Imidazoleglycerol-phosphate dehydratase
HPADDANE_00856	8.08e-143	-	-	-	-	-	-	-	-
HPADDANE_00857	1.7e-154	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HPADDANE_00858	4.81e-167	hisA	5.3.1.16, 5.3.1.24	-	E	ko:K01814,ko:K01817	ko00340,ko00400,ko01100,ko01110,ko01130,ko01230,map00340,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Histidine biosynthesis protein
HPADDANE_00859	8.61e-26	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2252)
HPADDANE_00860	0.0	glnA2	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HPADDANE_00861	7.81e-240	-	-	-	EGP	ko:K18567,ko:K19577	-	ko00000,ko02000	Major Facilitator Superfamily
HPADDANE_00862	1.71e-179	appC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HPADDANE_00863	1.32e-226	-	-	-	EP	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HPADDANE_00864	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HPADDANE_00865	0.0	-	-	-	P	ko:K02031,ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HPADDANE_00866	5.32e-220	-	-	-	M	-	-	-	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
HPADDANE_00867	0.0	hrpA	3.6.4.13	-	L	ko:K03578	-	ko00000,ko01000	Helicase associated domain (HA2) Add an annotation
HPADDANE_00868	2.72e-157	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase (PrmA)
HPADDANE_00869	0.0	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HPADDANE_00870	4.62e-225	ldh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HPADDANE_00871	6.04e-201	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HPADDANE_00872	5.62e-166	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HPADDANE_00873	2.11e-48	-	-	-	M	-	-	-	Lysin motif
HPADDANE_00874	7.06e-102	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HPADDANE_00875	1.31e-289	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
HPADDANE_00876	0.0	-	-	-	L	-	-	-	DNA helicase
HPADDANE_00877	3.86e-119	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HPADDANE_00878	9.64e-249	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HPADDANE_00879	2.74e-96	-	-	-	D	-	-	-	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
HPADDANE_00880	0.0	ftsI	3.4.16.4	-	M	ko:K03587	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011,ko03036	Penicillin-binding protein, transpeptidase domain protein
HPADDANE_00881	8.34e-197	-	-	-	M	-	-	-	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HPADDANE_00882	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HPADDANE_00883	7.84e-264	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HPADDANE_00884	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HPADDANE_00885	5.53e-285	ftsW	2.4.1.227	GT28	D	ko:K02563,ko:K03588	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011,ko02000,ko03036	Belongs to the SEDS family
HPADDANE_00886	2.82e-281	murG	2.4.1.227, 6.3.2.8	GT28	M	ko:K01924,ko:K02563	ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HPADDANE_00887	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
HPADDANE_00888	1.38e-234	ftsQ	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein FtsQ
HPADDANE_00891	7.5e-139	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HPADDANE_00892	3.46e-108	-	-	-	V	-	-	-	ABC-2 family transporter protein
HPADDANE_00893	1.2e-92	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
HPADDANE_00894	7.46e-59	-	-	-	K	-	-	-	Addiction module
HPADDANE_00895	4.31e-13	-	-	-	S	-	-	-	TIGRFAM Addiction module killer protein
HPADDANE_00896	8.16e-67	-	-	-	-	-	-	-	-
HPADDANE_00897	6.8e-110	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HPADDANE_00898	0.0	-	3.2.1.24	GH38	G	ko:K01191	ko00511,map00511	ko00000,ko00001,ko01000,ko04131	Alpha mannosidase, middle domain
HPADDANE_00900	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HPADDANE_00901	7.63e-221	dppB	-	-	EP	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HPADDANE_00902	9.32e-231	dppC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HPADDANE_00903	0.0	-	-	-	P	ko:K02031,ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HPADDANE_00904	9.52e-209	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HPADDANE_00905	2.27e-312	-	-	-	G	-	-	-	N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
HPADDANE_00906	0.0	-	-	-	S	ko:K09704	-	ko00000	Metal-independent alpha-mannosidase (GH125)
HPADDANE_00907	7.06e-218	-	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
HPADDANE_00908	9.89e-283	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HPADDANE_00909	2.61e-207	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HPADDANE_00910	6.36e-257	-	-	-	GK	-	-	-	ROK family
HPADDANE_00911	7.76e-192	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HPADDANE_00912	8.77e-297	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Amidohydrolase family
HPADDANE_00913	1.11e-254	-	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HPADDANE_00914	1.18e-139	-	-	-	U	ko:K02025,ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HPADDANE_00915	9.09e-159	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport systems inner membrane component
HPADDANE_00917	1.47e-98	-	-	-	F	-	-	-	NUDIX domain
HPADDANE_00918	0.0	pepP	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	Aminopeptidase P, N-terminal domain
HPADDANE_00919	1.12e-203	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HPADDANE_00920	0.0	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Mur ligase middle domain
HPADDANE_00921	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
HPADDANE_00922	1.36e-243	-	-	-	V	-	-	-	Acetyltransferase (GNAT) domain
HPADDANE_00923	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HPADDANE_00924	3.24e-164	sigH	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HPADDANE_00925	6.7e-72	-	-	-	-	-	-	-	-
HPADDANE_00926	6.47e-239	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
HPADDANE_00927	1.47e-245	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
HPADDANE_00928	7.95e-227	ispH	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HPADDANE_00929	3.74e-115	ybaK	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HPADDANE_00930	3.02e-253	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HPADDANE_00931	6.36e-172	-	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Thiamin pyrophosphokinase, vitamin B1 binding domain
HPADDANE_00932	3.43e-111	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HPADDANE_00933	1.4e-36	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L35
HPADDANE_00934	7.76e-81	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HPADDANE_00935	1.04e-215	xerD	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	recombinase XerD
HPADDANE_00936	8.08e-193	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
HPADDANE_00937	1.09e-199	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HPADDANE_00938	7.48e-149	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HPADDANE_00939	4.52e-198	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX hydrolase
HPADDANE_00940	0.0	nadA	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HPADDANE_00941	0.0	nadB	1.4.3.16, 2.4.2.19	-	H	ko:K00278,ko:K00767	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of L-aspartate to iminoaspartate
HPADDANE_00942	5.3e-208	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Quinolinate phosphoribosyl transferase, N-terminal domain
HPADDANE_00943	5.36e-272	iscS1	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class-V
HPADDANE_00944	0.0	typA	-	-	T	ko:K06207	-	ko00000	Elongation factor G C-terminus
HPADDANE_00946	3.43e-45	-	-	-	L	-	-	-	PFAM Integrase catalytic
HPADDANE_00947	6.23e-97	-	-	-	-	-	-	-	-
HPADDANE_00948	3.07e-243	pheA	4.2.1.51, 5.4.99.5	-	E	ko:K04518,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
HPADDANE_00949	1.01e-252	tyrA	1.3.1.12	-	E	ko:K00210,ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydrogenase
HPADDANE_00950	3.75e-57	-	-	-	-	-	-	-	-
HPADDANE_00951	8.32e-232	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
HPADDANE_00952	0.0	dppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
HPADDANE_00953	7.68e-202	dppB	-	-	EP	ko:K02033,ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HPADDANE_00954	1.28e-229	dppC	-	-	EP	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	N-terminal TM domain of oligopeptide transport permease C
HPADDANE_00955	0.0	-	-	-	EP	ko:K02031,ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
HPADDANE_00956	7.32e-214	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease/Exonuclease/phosphatase family
HPADDANE_00957	8.26e-191	-	-	-	S	-	-	-	Protein of unknown function (DUF3710)
HPADDANE_00958	1.02e-166	-	-	-	S	-	-	-	Protein of unknown function (DUF3159)
HPADDANE_00959	9.19e-304	rumA	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HPADDANE_00960	2.54e-148	-	-	-	-	-	-	-	-
HPADDANE_00961	0.0	ctpE	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
HPADDANE_00962	0.0	acnA	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HPADDANE_00963	2.89e-75	-	-	-	L	-	-	-	RelB antitoxin
HPADDANE_00964	2.66e-112	-	-	-	S	-	-	-	PIN domain
HPADDANE_00965	0.0	-	-	-	S	-	-	-	Protein of unknown function DUF262
HPADDANE_00966	7.84e-153	-	-	-	E	-	-	-	Psort location Cytoplasmic, score 8.87
HPADDANE_00967	5.28e-189	-	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HPADDANE_00968	6.31e-225	-	-	-	EG	-	-	-	EamA-like transporter family
HPADDANE_00969	1.9e-174	ywaC	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	Region found in RelA / SpoT proteins
HPADDANE_00970	2.16e-219	-	-	-	L	-	-	-	Transposase, Mutator family
HPADDANE_00974	6.2e-08	-	-	-	H	-	-	-	Flavoprotein
HPADDANE_00977	4.47e-76	-	-	-	S	-	-	-	ATPases associated with a variety of cellular activities
HPADDANE_00978	3.87e-258	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
HPADDANE_00979	5.67e-244	-	-	-	L	-	-	-	Transposase
HPADDANE_00980	0.0	miaB	2.8.4.3	-	H	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HPADDANE_00981	3.56e-233	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HPADDANE_00982	1.37e-175	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
HPADDANE_00983	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	FtsK SpoIIIE family protein
HPADDANE_00984	2.29e-149	pgsA	2.7.8.41, 2.7.8.5	-	I	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HPADDANE_00985	7.43e-119	cinA	3.5.1.42	-	S	ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
HPADDANE_00986	1.06e-106	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HPADDANE_00987	1.89e-51	-	-	-	S	-	-	-	Protein of unknown function (DUF3046)
HPADDANE_00988	4.14e-260	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HPADDANE_00989	6.44e-132	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
HPADDANE_00990	3.41e-152	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HPADDANE_00991	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HPADDANE_00992	3.39e-83	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HPADDANE_00993	2.49e-218	trpD	2.4.2.18	-	F	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HPADDANE_00994	3.99e-109	-	-	-	-	-	-	-	-
HPADDANE_00995	1.1e-166	plsC2	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
HPADDANE_00996	0.0	pknL	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	PASTA
HPADDANE_00997	2.86e-246	idsA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HPADDANE_00998	2.71e-158	-	-	-	-	-	-	-	-
HPADDANE_00999	1.19e-242	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HPADDANE_01000	0.0	gyrB2	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	DNA topoisomerase (ATP-hydrolyzing)
HPADDANE_01001	3.7e-264	-	-	-	G	-	-	-	Major Facilitator Superfamily
HPADDANE_01002	2.4e-218	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HPADDANE_01003	0.0	lhr	-	-	L	ko:K03724	-	ko00000,ko01000,ko03400	DEAD DEAH box helicase
HPADDANE_01004	2.75e-156	-	-	-	KT	-	-	-	RESPONSE REGULATOR receiver
HPADDANE_01005	0.0	gyrA2	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	DNA topoisomerase (ATP-hydrolyzing)
HPADDANE_01006	1.43e-296	-	-	-	S	-	-	-	Type I phosphodiesterase / nucleotide pyrophosphatase
HPADDANE_01007	7.13e-237	-	-	-	S	-	-	-	Protein of unknown function (DUF3071)
HPADDANE_01008	1.42e-62	-	-	-	S	-	-	-	Domain of unknown function (DUF4193)
HPADDANE_01009	1.62e-106	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
HPADDANE_01010	0.0	relA	2.7.6.5, 3.1.7.2	-	KT	ko:K00951,ko:K01139	ko00230,map00230	ko00000,ko00001,ko01000,ko03009	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HPADDANE_01011	1.15e-131	ppiA	5.2.1.8	-	G	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	ko00000,ko00001,ko01000,ko03110,ko04147	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HPADDANE_01012	1.05e-263	-	-	-	L	-	-	-	HTH-like domain
HPADDANE_01013	1.12e-286	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HPADDANE_01014	1.84e-142	-	-	-	L	-	-	-	Phage integrase family
HPADDANE_01015	6.34e-221	tnp7109-2	-	-	L	ko:K07493	-	ko00000	Transposase, Mutator family
HPADDANE_01016	3.47e-85	-	-	-	L	-	-	-	Phage integrase family
HPADDANE_01017	1.91e-260	-	-	-	L	ko:K03733	-	ko00000,ko03036	Phage integrase, N-terminal SAM-like domain
HPADDANE_01018	6.22e-14	-	-	-	L	-	-	-	PFAM Integrase catalytic
HPADDANE_01019	0.0	-	-	-	S	-	-	-	KAP family P-loop domain
HPADDANE_01020	6.06e-110	-	-	-	L	-	-	-	Resolvase, N terminal domain
HPADDANE_01021	0.0	-	-	-	S	-	-	-	AlwI restriction endonuclease
HPADDANE_01022	0.0	-	2.1.1.72	-	L	ko:K06223,ko:K07318	ko03430,map03430	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	DNA binding domain with preference for A/T rich regions
HPADDANE_01024	3.81e-162	intA	-	-	L	-	-	-	Phage integrase family
HPADDANE_01026	3.75e-98	-	-	-	-	-	-	-	-
HPADDANE_01028	1.57e-314	-	-	-	S	-	-	-	HipA-like C-terminal domain
HPADDANE_01029	4.88e-200	-	-	-	S	-	-	-	Fic/DOC family
HPADDANE_01031	8.12e-50	-	-	-	S	-	-	-	Fic/DOC family
HPADDANE_01033	1.12e-60	thiF	2.7.7.80	-	H	ko:K21029	ko04122,map04122	ko00000,ko00001,ko01000	Involved in molybdopterin and thiamine biosynthesis, family 2
HPADDANE_01034	5.35e-305	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HPADDANE_01035	3.91e-46	-	-	-	D	-	-	-	Filamentation induced by cAMP protein fic
HPADDANE_01036	1.44e-259	-	-	-	L	-	-	-	Transposase, Mutator family
HPADDANE_01037	3.96e-15	-	2.1.1.72	-	L	ko:K07316	-	ko00000,ko01000,ko02048	Belongs to the N(4) N(6)-methyltransferase family
HPADDANE_01039	1.53e-35	-	-	-	-	-	-	-	-
HPADDANE_01040	5.05e-185	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
HPADDANE_01041	3.74e-267	intA	-	-	L	-	-	-	Phage integrase family
HPADDANE_01042	5.48e-236	-	-	-	V	-	-	-	Abi-like protein
HPADDANE_01043	7.33e-09	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HPADDANE_01047	4.62e-36	-	-	-	L	ko:K07485	-	ko00000	Transposase
HPADDANE_01048	2.58e-32	-	-	-	D	-	-	-	COG COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HPADDANE_01050	1.08e-188	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
HPADDANE_01051	9.94e-134	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HPADDANE_01052	4.95e-216	-	-	-	-	-	-	-	-
HPADDANE_01053	4.57e-33	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HPADDANE_01054	3.66e-114	mutF	-	-	V	ko:K01990,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter ATP-binding
HPADDANE_01055	8.12e-78	mutE	-	-	S	ko:K20491	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
HPADDANE_01056	2.16e-72	mutG	-	-	S	ko:K20492	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	Lantibiotic protection ABC transporter permease subunit, MutG family
HPADDANE_01057	8.19e-113	-	-	-	-	ko:K20489	ko02020,ko02024,map02020,map02024	ko00000,ko00001	-
HPADDANE_01058	1.13e-125	-	-	-	T	ko:K20488	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
HPADDANE_01059	3.31e-146	-	2.7.13.3	-	T	ko:K20487	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	subtilin biosynthesis sensor protein SpaK
HPADDANE_01060	6.41e-55	-	-	-	-	-	-	-	-
HPADDANE_01061	8.78e-43	-	-	-	-	-	-	-	-
HPADDANE_01062	3.02e-205	-	-	-	EG	-	-	-	EamA-like transporter family
HPADDANE_01063	3.34e-92	pdxH	-	-	S	ko:K07006	-	ko00000	Pfam:Pyridox_oxidase
HPADDANE_01064	1.58e-300	-	-	-	L	-	-	-	ribosomal rna small subunit methyltransferase
HPADDANE_01065	1.59e-210	gpmB	3.1.3.85, 5.4.2.11	-	G	ko:K01834,ko:K22306	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Phosphoglycerate mutase family
HPADDANE_01066	4.94e-218	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HPADDANE_01067	3.66e-191	-	-	-	ET	ko:K10005	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
HPADDANE_01068	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
HPADDANE_01069	1.82e-99	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Helix-hairpin-helix motif
HPADDANE_01070	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein
HPADDANE_01071	5.83e-225	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
HPADDANE_01072	1.54e-130	tsaE	-	-	S	ko:K06925	-	ko00000,ko03016	Threonylcarbamoyl adenosine biosynthesis protein TsaE
HPADDANE_01073	7.76e-193	yeaZ	-	-	O	ko:K14742	-	ko00000,ko03016	Glycoprotease family
HPADDANE_01074	1.52e-127	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	FR47-like protein
HPADDANE_01075	3.79e-249	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HPADDANE_01077	2.76e-118	-	-	-	-	-	-	-	-
HPADDANE_01078	2.48e-204	-	-	-	S	-	-	-	Putative amidase domain
HPADDANE_01079	1.16e-241	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
HPADDANE_01081	4.05e-106	-	-	-	K	-	-	-	Transposase IS116 IS110 IS902
HPADDANE_01082	1.72e-27	-	-	-	S	-	-	-	SdpI/YhfL protein family
HPADDANE_01084	4.68e-46	-	-	-	I	-	-	-	radical SAM domain protein
HPADDANE_01085	5.76e-34	-	2.1.1.303	-	J	ko:K20421	ko01059,ko01130,map01059,map01130	ko00000,ko00001,ko00002,ko01000	protein-(glutamine-N5) methyltransferase activity
HPADDANE_01086	7.07e-121	-	-	-	V	ko:K06147	-	ko00000,ko02000	ATPases associated with a variety of cellular activities
HPADDANE_01087	1.54e-86	-	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	Type IV secretory system Conjugative DNA transfer
HPADDANE_01088	1.4e-26	-	-	-	L	-	-	-	Phage integrase family
HPADDANE_01091	1.86e-72	-	-	-	S	-	-	-	Fic/DOC family
HPADDANE_01093	8.36e-14	-	-	-	-	-	-	-	-
HPADDANE_01094	5.15e-21	-	-	-	-	-	-	-	-
HPADDANE_01095	3.52e-221	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
HPADDANE_01096	1.03e-22	-	-	-	L	-	-	-	PFAM Relaxase mobilization nuclease family protein
HPADDANE_01097	2.2e-252	-	-	-	V	ko:K20459	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HPADDANE_01098	2.53e-181	-	-	-	S	ko:K20460	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
HPADDANE_01099	4.02e-182	-	-	-	-	ko:K20461	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	-
HPADDANE_01100	9.7e-87	-	-	-	-	-	-	-	-
HPADDANE_01102	4.66e-299	-	-	-	T	-	-	-	Histidine kinase
HPADDANE_01103	3.01e-154	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
HPADDANE_01106	7.14e-138	-	-	-	M	-	-	-	Peptidase family M23
HPADDANE_01107	0.0	-	-	-	G	-	-	-	ABC transporter substrate-binding protein
HPADDANE_01108	9.93e-309	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the isocitrate and isopropylmalate dehydrogenases family
HPADDANE_01109	4.56e-266	guaB3	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	IMP dehydrogenase family protein
HPADDANE_01110	9.83e-92	-	-	-	-	-	-	-	-
HPADDANE_01111	0.0	fadD3	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	long-chain-fatty acid CoA ligase
HPADDANE_01112	4.26e-113	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HPADDANE_01113	1.37e-186	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
HPADDANE_01114	2.17e-184	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HPADDANE_01115	4.09e-166	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HPADDANE_01116	2.27e-116	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HPADDANE_01117	5.09e-217	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Cytidylyltransferase family
HPADDANE_01118	3.06e-283	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HPADDANE_01119	1.58e-95	-	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
HPADDANE_01120	3.4e-179	hisF	4.1.3.27	-	E	ko:K01657,ko:K02500	ko00340,ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00340,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HPADDANE_01121	1.55e-91	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HPADDANE_01122	0.0	trpE	4.1.3.27	-	E	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HPADDANE_01123	5.88e-146	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HPADDANE_01124	2.23e-210	-	-	-	S	-	-	-	Protein of unknown function (DUF979)
HPADDANE_01125	7.79e-153	-	-	-	S	-	-	-	Protein of unknown function (DUF969)
HPADDANE_01126	0.0	ybiT	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
HPADDANE_01127	1.96e-163	-	-	-	S	-	-	-	Enoyl-(Acyl carrier protein) reductase
HPADDANE_01128	5.98e-207	-	-	-	S	-	-	-	Protein conserved in bacteria
HPADDANE_01129	4.58e-82	-	-	-	S	-	-	-	Zincin-like metallopeptidase
HPADDANE_01130	4.82e-59	-	-	-	G	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HPADDANE_01131	1.6e-09	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HPADDANE_01132	8.67e-92	-	-	-	M	-	-	-	Putative peptidoglycan binding domain
HPADDANE_01133	1.15e-113	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HPADDANE_01134	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HPADDANE_01135	1.23e-147	-	-	-	S	-	-	-	Domain of unknown function (DUF4194)
HPADDANE_01136	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HPADDANE_01137	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HPADDANE_01138	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HPADDANE_01139	1.07e-236	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Shikimate dehydrogenase substrate binding domain
HPADDANE_01140	8.73e-234	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
HPADDANE_01141	1.42e-217	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
HPADDANE_01142	3.72e-281	pgk	2.7.2.3, 5.3.1.1	-	F	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Phosphoglycerate kinase
HPADDANE_01143	7.71e-186	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HPADDANE_01144	2.51e-47	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase SecG subunit
HPADDANE_01145	3.95e-224	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HPADDANE_01146	1.79e-208	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HPADDANE_01147	0.0	aspC	2.6.1.1, 2.6.1.2, 2.6.1.66	-	E	ko:K00812,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I II
HPADDANE_01148	8.78e-276	-	-	-	V	-	-	-	MatE
HPADDANE_01149	2.36e-276	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HPADDANE_01150	3.03e-256	tal	2.2.1.2	-	H	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HPADDANE_01151	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the transketolase family
HPADDANE_01152	1.82e-239	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HPADDANE_01153	1.33e-273	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HPADDANE_01154	4.79e-26	-	-	-	S	-	-	-	Putative phage holin Dp-1
HPADDANE_01155	2.58e-84	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HPADDANE_01156	1.85e-63	-	-	-	-	-	-	-	-
HPADDANE_01157	4.94e-27	-	-	-	-	-	-	-	-
HPADDANE_01158	5.13e-46	-	-	-	D	ko:K21449	-	ko00000,ko02000	nuclear chromosome segregation
HPADDANE_01159	2.24e-156	-	-	-	-	-	-	-	-
HPADDANE_01160	1.64e-62	-	-	-	-	-	-	-	-
HPADDANE_01161	3.33e-78	-	-	-	-	-	-	-	-
HPADDANE_01162	7.72e-259	-	-	-	S	-	-	-	Phage-related minor tail protein
HPADDANE_01163	9.4e-48	-	-	-	-	-	-	-	-
HPADDANE_01164	1.44e-74	-	-	-	-	-	-	-	-
HPADDANE_01166	4.92e-109	-	-	-	-	-	-	-	-
HPADDANE_01167	3.06e-53	-	-	-	-	-	-	-	-
HPADDANE_01168	3.91e-44	-	-	-	-	-	-	-	-
HPADDANE_01169	2.97e-67	-	-	-	-	-	-	-	-
HPADDANE_01170	1.41e-76	-	-	-	-	-	-	-	-
HPADDANE_01171	1.05e-98	-	-	-	S	-	-	-	P22 coat protein-protein 5 domain protein
HPADDANE_01172	4.25e-29	-	-	-	-	-	-	-	-
HPADDANE_01173	6.55e-124	-	-	-	-	-	-	-	-
HPADDANE_01174	3.62e-208	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
HPADDANE_01175	2.3e-126	-	-	-	S	-	-	-	Terminase
HPADDANE_01176	2.31e-208	-	-	-	S	-	-	-	Terminase
HPADDANE_01177	6.43e-38	-	-	-	-	-	-	-	-
HPADDANE_01178	8.49e-69	-	-	-	-	ko:K07451	-	ko00000,ko01000,ko02048	-
HPADDANE_01179	9.27e-117	-	-	-	J	-	-	-	tRNA 5'-leader removal
HPADDANE_01186	1.72e-46	-	-	-	A	ko:K13288	ko03008,map03008	ko00000,ko00001,ko01000,ko03009,ko03019	3'-to-5' exoribonuclease specific for small oligoribonucleotides
HPADDANE_01188	7.76e-84	-	-	-	V	-	-	-	HNH endonuclease
HPADDANE_01191	8.23e-100	-	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	ParB-like nuclease domain
HPADDANE_01193	2.08e-49	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
HPADDANE_01194	6.59e-221	tnp7109-2	-	-	L	ko:K07493	-	ko00000	Transposase, Mutator family
HPADDANE_01203	3.63e-39	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HPADDANE_01204	1.09e-09	-	-	-	-	-	-	-	-
HPADDANE_01205	7.48e-150	-	-	-	S	-	-	-	Virulence protein RhuM family
HPADDANE_01206	2.08e-71	-	-	-	-	-	-	-	-
HPADDANE_01207	3.87e-79	-	-	-	-	-	-	-	-
HPADDANE_01208	2.28e-126	-	-	-	-	-	-	-	-
HPADDANE_01209	7.09e-28	-	-	-	-	-	-	-	-
HPADDANE_01210	4.61e-136	-	-	-	L	-	-	-	Phage integrase family
HPADDANE_01211	3.59e-198	-	-	-	G	-	-	-	Fructosamine kinase
HPADDANE_01212	1.61e-196	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HPADDANE_01213	5.85e-142	-	-	-	S	-	-	-	PAC2 family
HPADDANE_01214	1.14e-37	-	-	-	S	-	-	-	PAC2 family
HPADDANE_01220	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HPADDANE_01221	3.78e-143	-	2.7.7.53	-	FG	ko:K19710	ko00230,map00230	ko00000,ko00001,ko01000	HIT domain
HPADDANE_01222	1.69e-156	yebC	-	-	K	-	-	-	transcriptional regulatory protein
HPADDANE_01223	1.58e-126	ruvC	3.1.22.4	-	L	ko:K01159	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
HPADDANE_01224	1.22e-114	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HPADDANE_01225	1.16e-242	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HPADDANE_01226	4.71e-51	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit
HPADDANE_01227	3.96e-115	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HPADDANE_01228	3.23e-270	sucC	6.2.1.5	-	F	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HPADDANE_01229	3.68e-202	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HPADDANE_01230	5.64e-310	-	-	-	-	-	-	-	-
HPADDANE_01231	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
HPADDANE_01232	1.69e-41	-	-	-	-	-	-	-	-
HPADDANE_01233	1.55e-208	-	-	-	U	ko:K06188	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HPADDANE_01234	3.69e-183	rluB	5.4.99.19, 5.4.99.22	-	J	ko:K06178,ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HPADDANE_01235	0.0	der	-	-	F	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HPADDANE_01237	0.0	ugp	2.7.7.9	-	G	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HPADDANE_01238	0.0	-	-	-	K	-	-	-	WYL domain
HPADDANE_01239	1.86e-64	-	-	-	-	-	-	-	-
HPADDANE_01240	0.0	helY	-	-	L	ko:K03727	-	ko00000,ko01000	DEAD DEAH box helicase
HPADDANE_01241	6.43e-81	rbpA	-	-	K	-	-	-	Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
HPADDANE_01242	9.81e-175	nt5e	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD-hyrolase-like
HPADDANE_01244	1.74e-95	-	-	-	S	-	-	-	N-methyltransferase activity
HPADDANE_01245	4.85e-42	-	-	-	L	-	-	-	Transposase
HPADDANE_01248	2.65e-30	hipA	2.7.11.1	-	S	ko:K07154	-	ko00000,ko01000,ko01001,ko02048	HipA N-terminal domain protein
HPADDANE_01250	6.8e-163	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
HPADDANE_01251	7.41e-109	-	-	-	L	-	-	-	Resolvase, N terminal domain
HPADDANE_01252	7.98e-123	cad	-	-	P	-	-	-	Cadmium resistance transporter
HPADDANE_01253	5.63e-77	cmtR	-	-	K	ko:K21885	-	ko00000,ko03000	Bacterial regulatory protein, arsR family
HPADDANE_01254	1.16e-72	-	-	-	L	-	-	-	Resolvase, N terminal domain
HPADDANE_01255	1.33e-36	-	-	-	L	-	-	-	Resolvase, N terminal domain
HPADDANE_01257	6.12e-144	-	-	-	S	-	-	-	AIPR protein
HPADDANE_01259	3.91e-84	-	-	-	L	-	-	-	protein secretion by the type IV secretion system
HPADDANE_01260	7.77e-20	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
HPADDANE_01262	1.29e-55	hrtA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HPADDANE_01264	3.1e-73	-	-	-	-	-	-	-	-
HPADDANE_01265	3.85e-144	merR2	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HPADDANE_01266	1.17e-96	garA	-	-	T	-	-	-	Inner membrane component of T3SS, cytoplasmic domain
HPADDANE_01267	1.26e-178	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
HPADDANE_01268	7.03e-51	sbp	-	-	S	-	-	-	Protein of unknown function (DUF1290)
HPADDANE_01269	9.47e-200	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
HPADDANE_01270	7.77e-137	pgsA2	2.7.8.41, 2.7.8.5	-	I	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HPADDANE_01271	5.28e-201	hisG	2.4.2.17	-	F	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	ATP phosphoribosyltransferase
HPADDANE_01272	3.56e-56	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Phosphoribosyl-ATP pyrophosphohydrolase
HPADDANE_01273	1.14e-151	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribulose-phosphate 3-epimerase
HPADDANE_01274	2.32e-236	lgt	-	-	M	-	-	-	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HPADDANE_01275	5.09e-207	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HPADDANE_01276	0.0	trpB	4.2.1.20	-	E	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HPADDANE_01277	1.36e-139	-	-	-	S	-	-	-	SOS response associated peptidase (SRAP)
HPADDANE_01278	1.67e-108	-	-	-	G	ko:K02445,ko:K03762	-	ko00000,ko02000	transmembrane transporter activity
HPADDANE_01279	2.49e-195	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HPADDANE_01280	0.0	-	-	-	E	ko:K16235	-	ko00000,ko02000	amino acid
HPADDANE_01281	2.77e-107	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HPADDANE_01282	1.47e-241	-	-	-	V	-	-	-	VanZ like family
HPADDANE_01283	2.07e-18	cefD	5.1.1.17	-	E	ko:K04127	ko00311,ko01100,ko01130,map00311,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Aminotransferase, class V
HPADDANE_01284	4.46e-21	cefD	5.1.1.17	-	E	ko:K04127	ko00311,ko01100,ko01130,map00311,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Aminotransferase, class V
HPADDANE_01285	7.82e-118	-	-	-	K	-	-	-	FR47-like protein
HPADDANE_01286	6.13e-47	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2316)
HPADDANE_01287	1.51e-127	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HPADDANE_01288	6.8e-58	-	-	-	L	-	-	-	Transposase
HPADDANE_01289	0.0	-	-	-	E	ko:K03307	-	ko00000	Sodium:solute symporter family
HPADDANE_01290	3.63e-54	-	-	-	-	-	-	-	-
HPADDANE_01291	2.32e-19	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HPADDANE_01292	1.49e-53	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
HPADDANE_01293	1.69e-34	-	-	-	G	-	-	-	Transporter major facilitator family protein
HPADDANE_01294	0.0	-	-	-	E	ko:K16235	-	ko00000,ko02000	amino acid
HPADDANE_01295	1.52e-10	-	-	-	-	-	-	-	-
HPADDANE_01296	2.03e-84	-	-	-	K	-	-	-	Protein of unknown function, DUF488
HPADDANE_01297	1.18e-98	-	-	-	-	-	-	-	-
HPADDANE_01298	2.79e-199	-	-	-	-	-	-	-	-
HPADDANE_01299	5.5e-20	-	-	-	S	ko:K09974	-	ko00000	Domain of unknown function (DUF1287)
HPADDANE_01301	5.14e-24	-	-	-	S	-	-	-	Virulence protein RhuM family
HPADDANE_01302	1.11e-57	-	-	-	K	-	-	-	Protein of unknown function, DUF488
HPADDANE_01303	8.07e-230	-	-	-	KL	-	-	-	DEAD-like helicases superfamily
HPADDANE_01304	3.94e-294	-	2.6.1.1	-	E	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Psort location Cytoplasmic, score 8.87
HPADDANE_01305	0.0	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HPADDANE_01306	1.52e-154	-	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HPADDANE_01307	6.92e-22	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
HPADDANE_01308	2.56e-220	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
HPADDANE_01309	3.71e-260	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HPADDANE_01310	2.17e-39	-	-	-	-	-	-	-	-
HPADDANE_01311	1.33e-159	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HPADDANE_01312	8.4e-234	pyrD	1.3.1.14	-	F	ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HPADDANE_01313	3.19e-202	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
HPADDANE_01314	2.12e-224	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the OMP decarboxylase family. Type 2 subfamily
HPADDANE_01315	0.0	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HPADDANE_01316	3.7e-96	pyrI	-	-	F	ko:K00610	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002	Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
HPADDANE_01317	4.13e-228	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HPADDANE_01318	0.0	glnE	2.7.7.42, 2.7.7.89	-	H	ko:K00982	-	ko00000,ko01000	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
HPADDANE_01319	1.4e-238	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HPADDANE_01320	5.25e-197	metF	1.5.1.20	-	E	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Methylenetetrahydrofolate reductase
HPADDANE_01321	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HPADDANE_01322	3.11e-124	sixA	-	-	T	ko:K08296	-	ko00000,ko01000	Phosphoglycerate mutase family
HPADDANE_01323	1.04e-246	trmI	2.1.1.219, 2.1.1.220	-	J	ko:K07442	-	ko00000,ko01000,ko03016	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
HPADDANE_01324	1.26e-119	-	-	-	S	ko:K06999	-	ko00000	Phospholipase/Carboxylesterase
HPADDANE_01326	1.13e-169	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HPADDANE_01327	1.29e-139	-	-	-	S	-	-	-	phosphoesterase or phosphohydrolase
HPADDANE_01328	3.04e-28	-	-	-	S	-	-	-	Aldo/keto reductase family
HPADDANE_01329	2.77e-15	-	-	-	S	-	-	-	Aldo/keto reductase family
HPADDANE_01330	7.57e-215	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HPADDANE_01331	1.13e-215	CP_1020	-	-	S	-	-	-	zinc ion binding
HPADDANE_01332	3.61e-161	-	-	-	S	-	-	-	Plasmid pRiA4b ORF-3-like protein
HPADDANE_01333	4.99e-44	rarD	-	-	S	ko:K05786	-	ko00000,ko02000	EamA-like transporter family
HPADDANE_01334	9.36e-22	-	-	-	E	-	-	-	Rard protein
HPADDANE_01335	2.35e-253	-	-	-	L	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
HPADDANE_01336	2.85e-41	-	-	-	S	-	-	-	MazG-like family
HPADDANE_01337	1.31e-17	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HPADDANE_01338	1.02e-75	CP_1020	-	-	S	-	-	-	zinc ion binding
HPADDANE_01339	4.54e-177	-	-	-	-	-	-	-	-
HPADDANE_01340	2.97e-119	bcp	1.11.1.15	-	O	ko:K03564	-	ko00000,ko01000	Redoxin
HPADDANE_01341	5.09e-58	-	-	-	L	-	-	-	Transposase, Mutator family
HPADDANE_01342	2.69e-46	-	-	-	L	-	-	-	Transposase
HPADDANE_01344	4.84e-223	xylR	-	-	GK	-	-	-	ROK family
HPADDANE_01345	0.0	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
HPADDANE_01347	5.29e-46	-	-	-	L	-	-	-	Transposase
HPADDANE_01349	4.61e-226	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HPADDANE_01350	5.69e-280	-	-	-	G	ko:K02027,ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HPADDANE_01351	4.31e-207	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	PFAM binding-protein-dependent transport systems inner membrane component
HPADDANE_01352	1.28e-186	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HPADDANE_01353	0.0	-	3.2.1.177	GH31	G	ko:K01811	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 31 family
HPADDANE_01354	4.08e-137	-	-	-	L	-	-	-	IstB-like ATP binding protein
HPADDANE_01355	6.52e-40	-	-	-	L	ko:K07485	-	ko00000	Transposase
HPADDANE_01356	6.59e-221	tnp7109-2	-	-	L	ko:K07493	-	ko00000	Transposase, Mutator family
HPADDANE_01358	0.0	xylA	5.3.1.5	-	G	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko01000	Belongs to the xylose isomerase family
HPADDANE_01359	1.02e-78	-	-	-	K	ko:K02529,ko:K17640	-	ko00000,ko03000	Bacterial regulatory proteins, lacI family
HPADDANE_01360	3.96e-109	-	-	-	K	ko:K02529,ko:K17640	-	ko00000,ko03000	Bacterial regulatory proteins, lacI family
HPADDANE_01361	5.05e-186	-	-	-	G	ko:K02027,ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter periplasmic binding protein YcjN precursor K02027
HPADDANE_01362	5.22e-157	-	-	-	U	ko:K02025,ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HPADDANE_01363	2.03e-155	-	-	-	P	ko:K02026,ko:K10119,ko:K17243	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HPADDANE_01364	0.0	-	3.2.1.37	GH43	G	ko:K01198	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
HPADDANE_01365	9.49e-93	-	-	-	L	-	-	-	Transposase
HPADDANE_01366	4.06e-123	-	-	-	L	-	-	-	Transposase
HPADDANE_01367	1.3e-200	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HPADDANE_01368	1.03e-202	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HPADDANE_01369	1.53e-308	glgA	2.4.1.342	GT4	G	ko:K16148	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000,ko01003	Starch synthase catalytic domain
HPADDANE_01370	5.92e-107	-	-	-	-	-	-	-	-
HPADDANE_01371	0.0	-	-	-	S	-	-	-	Glycosyl hydrolases related to GH101 family, GH129
HPADDANE_01372	0.0	dppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
HPADDANE_01373	0.0	gltD	1.4.1.13, 1.4.1.14	-	C	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
HPADDANE_01374	0.0	gltB	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase NADPH large subunit
HPADDANE_01375	7.3e-227	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HPADDANE_01378	1.19e-177	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
HPADDANE_01379	2.36e-226	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
HPADDANE_01380	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HPADDANE_01381	2.75e-46	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
HPADDANE_01382	1.98e-162	-	-	-	S	-	-	-	UPF0126 domain
HPADDANE_01383	6.04e-149	mazG	3.6.1.66	-	S	ko:K02428,ko:K02499	ko00230,map00230	ko00000,ko00001,ko01000,ko03036	Psort location Cytoplasmic, score 8.87
HPADDANE_01384	2.61e-286	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Amino-transferase class IV
HPADDANE_01385	1.54e-112	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HPADDANE_01386	4.41e-247	-	-	-	S	ko:K06889	-	ko00000	alpha beta
HPADDANE_01387	4.45e-310	pntB	1.6.1.2	-	C	ko:K00325	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
HPADDANE_01388	5.05e-58	pntAB	1.6.1.2	-	C	ko:K00324	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	4TM region of pyridine nucleotide transhydrogenase, mitoch
HPADDANE_01389	5.23e-258	pntA	1.6.1.2	-	C	ko:K00324	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	NAD(P) transhydrogenase subunit alpha part 1 K00324
HPADDANE_01390	0.0	fadD2	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
HPADDANE_01391	5.61e-232	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HPADDANE_01392	0.0	corC	-	-	S	-	-	-	CBS domain
HPADDANE_01393	1.44e-132	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HPADDANE_01394	2.04e-273	phoH	-	-	T	ko:K06217	-	ko00000	PhoH-like protein
HPADDANE_01395	9.63e-77	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
HPADDANE_01396	1.97e-187	-	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HPADDANE_01398	1.53e-209	spoU2	-	-	J	-	-	-	SpoU rRNA Methylase family
HPADDANE_01399	5.12e-306	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HPADDANE_01400	1e-144	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HPADDANE_01401	1.18e-132	iscU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
HPADDANE_01402	1.07e-303	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HPADDANE_01403	3.98e-184	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
HPADDANE_01404	2.15e-301	sufD	-	-	O	ko:K09015	-	ko00000	FeS assembly protein SufD
HPADDANE_01405	0.0	sufB	-	-	O	ko:K09014	-	ko00000	FeS assembly protein SufB
HPADDANE_01406	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HPADDANE_01407	2.09e-104	aroQ	4.2.1.10	-	E	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a trans-dehydration via an enolate intermediate
HPADDANE_01408	0.0	aroB	2.7.1.71, 4.2.3.4	-	H	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HPADDANE_01409	4.5e-279	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HPADDANE_01410	2.5e-100	-	3.4.23.43	-	S	ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	Type IV leader peptidase family
HPADDANE_01411	2.14e-260	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HPADDANE_01412	6.41e-103	ruvX	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HPADDANE_01413	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HPADDANE_01414	9.36e-48	-	-	-	-	-	-	-	-
HPADDANE_01415	2.87e-83	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF948)
HPADDANE_01416	2e-165	-	5.4.2.12	-	G	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Phosphoglycerate mutase family
HPADDANE_01417	1.81e-07	-	-	-	L	-	-	-	Helix-turn-helix domain
HPADDANE_01418	2.55e-65	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
HPADDANE_01419	1.01e-83	-	-	-	T	-	-	-	PemK-like, MazF-like toxin of type II toxin-antitoxin system
HPADDANE_01420	8.9e-71	-	-	-	E	-	-	-	Transglutaminase-like superfamily
HPADDANE_01421	2.38e-46	-	-	-	S	-	-	-	SdpI/YhfL protein family
HPADDANE_01422	2.01e-61	-	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	cytidine deaminase activity
HPADDANE_01423	1.35e-196	-	-	-	S	ko:K07010	-	ko00000,ko01002	Peptidase C26
HPADDANE_01424	1.29e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HPADDANE_01425	6.47e-205	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HPADDANE_01426	1.09e-275	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HPADDANE_01427	2.11e-85	-	-	-	S	-	-	-	Domain of unknown function (DUF4418)
HPADDANE_01428	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HPADDANE_01429	7.32e-136	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HPADDANE_01430	1e-305	pbuX	-	-	F	ko:K03458	-	ko00000	Permease family
HPADDANE_01431	6.32e-42	-	-	-	K	ko:K07727	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
HPADDANE_01432	4.93e-49	-	-	-	S	-	-	-	Protein of unknown function (DUF2975)
HPADDANE_01433	1.25e-203	-	-	-	I	-	-	-	Serine aminopeptidase, S33
HPADDANE_01434	9.95e-216	-	-	-	M	-	-	-	pfam nlp p60
HPADDANE_01435	3.92e-95	gloA	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HPADDANE_01436	3.72e-139	pncA	3.5.1.19	-	Q	ko:K08281	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Isochorismatase family
HPADDANE_01437	1.02e-142	pepE	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Peptidase family S51
HPADDANE_01438	1.67e-259	-	-	-	-	-	-	-	-
HPADDANE_01439	4.66e-56	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
HPADDANE_01440	0.000124	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HPADDANE_01441	1.62e-117	-	-	-	K	-	-	-	Helix-turn-helix domain
HPADDANE_01442	1.16e-133	-	-	-	S	-	-	-	PIN domain
HPADDANE_01443	0.0	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
HPADDANE_01444	0.0	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HPADDANE_01445	8.55e-288	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HPADDANE_01446	6.18e-238	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HPADDANE_01447	8.96e-13	-	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
HPADDANE_01448	1.41e-286	-	-	-	T	-	-	-	Histidine kinase
HPADDANE_01449	3.12e-142	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
HPADDANE_01450	1.11e-146	-	-	-	P	ko:K07220	-	ko00000	Protein of unknown function DUF47
HPADDANE_01451	2.33e-240	pitB	-	-	P	ko:K03306	-	ko00000	Phosphate transporter family
HPADDANE_01452	0.0	nplT	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
HPADDANE_01453	3.15e-55	-	-	-	K	-	-	-	WHG domain
HPADDANE_01454	1.01e-38	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HPADDANE_01455	7.14e-40	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HPADDANE_01456	0.0	-	-	-	JKL	-	-	-	helicase superfamily c-terminal domain
HPADDANE_01458	2.15e-297	rutG	-	-	F	ko:K02824,ko:K03458	-	ko00000,ko02000	Permease family
HPADDANE_01459	2.09e-208	-	-	-	G	-	-	-	Phosphoglycerate mutase family
HPADDANE_01460	7.32e-136	-	-	-	E	-	-	-	haloacid dehalogenase-like hydrolase
HPADDANE_01461	2.63e-302	-	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
HPADDANE_01462	3.07e-07	yccF	-	-	S	-	-	-	Inner membrane component domain
HPADDANE_01463	3.4e-05	gloA	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HPADDANE_01464	9.23e-168	-	-	-	S	ko:K07090	-	ko00000	Sulfite exporter TauE/SafE
HPADDANE_01467	1.5e-47	-	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA
HPADDANE_01468	5.76e-115	-	-	-	S	-	-	-	Helix-turn-helix
HPADDANE_01469	1.58e-267	-	-	-	S	-	-	-	Short C-terminal domain
HPADDANE_01470	3.51e-52	-	-	-	-	-	-	-	-
HPADDANE_01471	5.15e-304	-	-	-	-	-	-	-	-
HPADDANE_01472	3.77e-97	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HPADDANE_01473	0.0	-	-	-	KLT	-	-	-	Protein tyrosine kinase
HPADDANE_01474	0.0	-	-	-	U	-	-	-	Drug resistance MFS transporter, drug H antiporter-2 family
HPADDANE_01475	7.74e-17	-	-	-	-	-	-	-	-
HPADDANE_01476	2.86e-152	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HPADDANE_01477	8.02e-278	-	-	-	G	-	-	-	Transmembrane secretion effector
HPADDANE_01478	8.51e-22	-	-	-	K	ko:K21498	-	ko00000,ko02048	addiction module antidote protein HigA
HPADDANE_01479	2.85e-305	-	-	-	S	-	-	-	HipA-like C-terminal domain
HPADDANE_01480	2.95e-50	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
HPADDANE_01481	5.72e-69	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
HPADDANE_01482	2.06e-104	-	-	-	S	-	-	-	Cupin 2, conserved barrel domain protein
HPADDANE_01483	2.93e-201	-	-	-	J	-	-	-	Methyltransferase domain
HPADDANE_01484	5.5e-79	yccF	-	-	S	-	-	-	Inner membrane component domain
HPADDANE_01485	7.16e-296	-	-	-	K	-	-	-	Fic/DOC family
HPADDANE_01486	5.54e-33	-	-	-	L	-	-	-	Transposase, Mutator family
HPADDANE_01487	0.0	-	-	-	L	-	-	-	ABC transporter
HPADDANE_01488	1.57e-312	-	-	-	V	-	-	-	MatE
HPADDANE_01489	2.31e-36	-	-	-	S	ko:K02890,ko:K07343	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	rRNA binding
HPADDANE_01490	6.47e-208	tetD	-	-	K	ko:K13653	-	ko00000,ko03000	Arac family
HPADDANE_01491	6.16e-260	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HPADDANE_01492	4.58e-181	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HPADDANE_01493	0.0	pip	3.4.11.5	-	S	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	alpha/beta hydrolase fold
HPADDANE_01494	0.0	-	-	-	T	-	-	-	Histidine kinase
HPADDANE_01495	7.92e-187	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
HPADDANE_01496	0.0	-	-	-	MV	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HPADDANE_01497	5.11e-183	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HPADDANE_01498	1.97e-313	-	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Aminotransferase class-V
HPADDANE_01499	3.75e-209	pdxY	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
HPADDANE_01500	1.47e-120	yraN	-	-	L	ko:K07460	-	ko00000	Belongs to the UPF0102 family
HPADDANE_01501	0.0	comM	-	-	O	ko:K07391	-	ko00000	Magnesium chelatase, subunit ChlI C-terminal
HPADDANE_01502	0.0	dprA	-	-	LU	ko:K04096	-	ko00000	DNA recombination-mediator protein A
HPADDANE_01503	0.0	sdhA	1.3.5.1, 1.3.5.4, 1.4.3.16	-	C	ko:K00239,ko:K00278	ko00020,ko00190,ko00250,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00250,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	Succinate dehydrogenase flavoprotein subunit
HPADDANE_01504	1.33e-229	sdhB	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
HPADDANE_01505	6.02e-142	safC	-	-	S	-	-	-	O-methyltransferase
HPADDANE_01506	2.65e-200	fmt2	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
HPADDANE_01507	1.39e-312	nhaA	-	-	P	ko:K03313	-	ko00000,ko02000	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HPADDANE_01510	6.34e-316	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HPADDANE_01511	1.89e-160	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HPADDANE_01512	4.2e-151	clpP1	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HPADDANE_01513	6.93e-79	-	-	-	-	-	-	-	-
HPADDANE_01514	1.22e-298	-	-	-	P	ko:K03281	-	ko00000	Voltage gated chloride channel
HPADDANE_01515	2.01e-303	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HPADDANE_01516	0.0	rnd	3.1.13.5	-	J	ko:K03684	-	ko00000,ko01000,ko03016	3'-5' exonuclease
HPADDANE_01517	3.32e-155	-	-	-	S	-	-	-	Protein of unknown function (DUF3000)
HPADDANE_01518	3e-221	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HPADDANE_01519	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
HPADDANE_01520	9.66e-46	-	-	-	-	-	-	-	-
HPADDANE_01521	0.0	nadE	6.3.5.1	-	H	ko:K01950	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HPADDANE_01522	7.79e-283	-	-	-	S	-	-	-	Peptidase dimerisation domain
HPADDANE_01523	1.12e-145	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HPADDANE_01524	3.84e-277	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HPADDANE_01525	5.79e-222	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	NLPA lipoprotein
HPADDANE_01526	3.76e-204	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HPADDANE_01527	9.49e-266	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HPADDANE_01528	1.61e-164	macB	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HPADDANE_01529	3.02e-126	-	-	-	M	ko:K02005,ko:K13888	-	ko00000,ko00002,ko02000	Efflux transporter, RND family, MFP subunit
HPADDANE_01530	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
HPADDANE_01531	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
HPADDANE_01533	0.0	yrhL	-	-	I	-	-	-	Psort location CytoplasmicMembrane, score 9.99
HPADDANE_01534	1.59e-244	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HPADDANE_01536	0.0	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HPADDANE_01537	6.32e-83	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HPADDANE_01538	1.18e-158	gpmB	3.1.3.85, 5.4.2.11	-	G	ko:K01834,ko:K22306	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Phosphoglycerate mutase family
HPADDANE_01541	0.0	pta	2.3.1.8	-	C	ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	phosphate acetyltransferase
HPADDANE_01542	2.87e-289	ackA	2.7.2.1	-	H	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HPADDANE_01543	3.55e-315	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HPADDANE_01544	5.77e-252	-	-	-	-	-	-	-	-
HPADDANE_01546	3.41e-18	-	-	-	K	-	-	-	Putative zinc ribbon domain
HPADDANE_01547	0.0	glgX	3.2.1.68	CBM48,GH13	G	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 13 family
HPADDANE_01548	1.9e-160	-	-	-	L	-	-	-	NUDIX domain
HPADDANE_01549	3.98e-228	-	-	-	L	-	-	-	NIF3 (NGG1p interacting factor 3)
HPADDANE_01550	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HPADDANE_01551	3.04e-164	pdtaR	-	-	T	ko:K22010	-	ko00000,ko00002,ko02022	Response regulator receiver domain protein
HPADDANE_01552	3.66e-185	intA	-	-	L	-	-	-	Phage integrase family
HPADDANE_01556	1.76e-13	-	-	-	S	-	-	-	Protein of unknown function (DUF1778)
HPADDANE_01557	5.25e-50	-	-	-	-	-	-	-	-
HPADDANE_01558	1.61e-36	-	-	-	-	-	-	-	-
HPADDANE_01561	4.58e-09	-	-	-	-	-	-	-	-
HPADDANE_01562	7.55e-168	-	-	-	M	-	-	-	Bacteriophage peptidoglycan hydrolase
HPADDANE_01565	4.9e-84	-	-	-	-	-	-	-	-
HPADDANE_01566	2.37e-174	-	-	-	-	-	-	-	-
HPADDANE_01573	2.8e-83	-	2.1.1.72	-	L	ko:K06223	ko03430,map03430	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	D12 class N6 adenine-specific DNA methyltransferase
HPADDANE_01574	1.43e-66	-	-	-	-	-	-	-	-
HPADDANE_01579	1.94e-27	-	-	-	-	ko:K03646	-	ko00000,ko02000	-
HPADDANE_01580	0.0	-	-	-	D	-	-	-	Cell surface antigen C-terminus
HPADDANE_01581	2.42e-11	-	-	-	M	-	-	-	cell wall anchor domain protein
HPADDANE_01582	6.78e-88	-	-	-	M	-	-	-	Listeria-Bacteroides repeat domain (List_Bact_rpt)
HPADDANE_01583	5.53e-57	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
HPADDANE_01584	1.26e-61	-	-	-	D	-	-	-	nuclear chromosome segregation
HPADDANE_01585	1.36e-16	-	-	-	K	ko:K21498	-	ko00000,ko02048	Helix-turn-helix
HPADDANE_01589	1.55e-66	-	-	-	-	-	-	-	-
HPADDANE_01592	4.91e-48	-	-	-	S	-	-	-	AAA domain, putative AbiEii toxin, Type IV TA system
HPADDANE_01594	4.98e-235	-	-	-	U	-	-	-	Type IV secretory pathway, VirB4
HPADDANE_01595	1.95e-268	-	-	-	U	-	-	-	TraM recognition site of TraD and TraG
HPADDANE_01600	1.67e-93	-	-	-	-	-	-	-	-
HPADDANE_01602	1.19e-15	-	-	-	S	-	-	-	Helix-turn-helix domain
HPADDANE_01603	1.52e-269	-	-	-	S	-	-	-	Helix-turn-helix domain
HPADDANE_01604	7.3e-112	-	-	-	S	ko:K18955	-	ko00000,ko03000	Transcription factor WhiB
HPADDANE_01605	1.11e-133	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	AAA domain
HPADDANE_01606	1.33e-49	-	-	-	-	-	-	-	-
HPADDANE_01610	1.55e-65	spaF	-	-	V	ko:K01990,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HPADDANE_01613	2.38e-85	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter
HPADDANE_01614	0.0	-	-	-	D	-	-	-	Cell surface antigen C-terminus
HPADDANE_01616	0.0	-	-	-	L	-	-	-	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HPADDANE_01620	6.06e-36	-	-	-	DJ	ko:K06218	-	ko00000,ko02048	Addiction module toxin, RelE StbE family
HPADDANE_01621	2.24e-37	-	-	-	S	-	-	-	Antitoxin component of a toxin-antitoxin (TA) module
HPADDANE_01627	3.58e-12	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
HPADDANE_01629	9.62e-16	-	-	-	L	-	-	-	Domain of unknown function (DUF3846)
HPADDANE_01634	2.77e-84	-	-	-	S	-	-	-	Glutamine amidotransferases class-II
HPADDANE_01637	9.36e-35	-	-	-	S	-	-	-	Protein of unknown function (DUF1778)
HPADDANE_01638	1.79e-76	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HPADDANE_01640	4.35e-198	-	3.6.4.12	-	F	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	RecQ zinc-binding
HPADDANE_01641	3.38e-67	-	-	-	L	-	-	-	helicase
HPADDANE_01643	1.63e-97	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HPADDANE_01644	5.96e-126	-	-	-	S	-	-	-	Nucleotidyl transferase AbiEii toxin, Type IV TA system
HPADDANE_01649	1.03e-22	-	-	-	-	-	-	-	-
HPADDANE_01650	2.71e-52	-	-	-	-	-	-	-	-
HPADDANE_01653	3.27e-43	-	-	-	-	-	-	-	-
HPADDANE_01654	6.32e-81	-	-	-	K	-	-	-	Helix-turn-helix domain
HPADDANE_01659	1.65e-68	ydhQ	2.7.11.1	-	MU	ko:K12132	-	ko00000,ko01000,ko01001	cell adhesion
HPADDANE_01664	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Pyruvate kinase
HPADDANE_01665	6.59e-229	terC	-	-	P	ko:K05794	-	ko00000	Integral membrane protein, TerC family
HPADDANE_01666	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HPADDANE_01667	3.71e-79	-	-	-	T	-	-	-	Histidine kinase
HPADDANE_01668	5.28e-81	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
HPADDANE_01670	4.91e-177	XK27_10205	-	-	-	ko:K02004	-	ko00000,ko00002,ko02000	-
HPADDANE_01671	4.34e-95	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HPADDANE_01672	8.89e-94	coaE	2.7.1.24	-	H	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HPADDANE_01673	0.0	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
HPADDANE_01674	6.91e-201	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HPADDANE_01675	7.75e-247	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Zinc-uptake complex component A periplasmic
HPADDANE_01676	2.08e-209	-	-	-	P	ko:K02074	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HPADDANE_01677	1.34e-175	znuB	-	-	U	ko:K02075	-	ko00000,ko00002,ko02000	ABC 3 transport family
HPADDANE_01678	2.82e-117	ispF	2.7.7.60, 4.6.1.12	-	H	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HPADDANE_01679	1.85e-131	carD	-	-	K	ko:K07736	-	ko00000,ko03000	CarD-like/TRCF domain
HPADDANE_01680	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HPADDANE_01681	2.47e-164	cseB	-	-	T	-	-	-	Response regulator receiver domain protein
HPADDANE_01682	8.46e-242	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HPADDANE_01683	5.89e-81	umuD	-	-	KT	ko:K03503	-	ko00000,ko01000,ko01002,ko03400	Peptidase S24-like
HPADDANE_01684	3.66e-73	pyrE_1	-	-	S	-	-	-	Phosphoribosyl transferase domain
HPADDANE_01685	2.5e-191	-	-	-	T	-	-	-	Eukaryotic phosphomannomutase
HPADDANE_01686	2.03e-84	-	-	-	S	-	-	-	Zincin-like metallopeptidase
HPADDANE_01687	0.0	-	-	-	-	-	-	-	-
HPADDANE_01688	0.0	-	-	-	S	-	-	-	Glycosyl transferase, family 2
HPADDANE_01689	7.16e-75	whiB2	-	-	K	ko:K18955	-	ko00000,ko03000	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
HPADDANE_01690	1.54e-208	lytR2	-	-	K	-	-	-	Cell envelope-related transcriptional attenuator domain
HPADDANE_01691	0.0	-	-	-	D	ko:K03466	-	ko00000,ko03036	FtsK/SpoIIIE family
HPADDANE_01692	3.32e-61	whiB	-	-	K	ko:K18955	-	ko00000,ko03000	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
HPADDANE_01693	0.0	pdtaS	2.7.13.3	-	T	ko:K00936	-	ko00000,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HPADDANE_01694	6.13e-172	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	Haemolysin-III related
HPADDANE_01695	7.1e-106	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HPADDANE_01696	1.59e-95	fkbP	5.2.1.8	-	G	ko:K01802	-	ko00000,ko01000	Peptidyl-prolyl cis-trans
HPADDANE_01697	0.0	sdaA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase alpha chain
HPADDANE_01698	8.17e-122	-	-	-	-	-	-	-	-
HPADDANE_01699	1.19e-172	int8	-	-	L	-	-	-	Phage integrase family
HPADDANE_01700	5.75e-31	-	-	-	N	-	-	-	HicA toxin of bacterial toxin-antitoxin,
HPADDANE_01701	1.29e-25	-	-	-	S	-	-	-	PFAM Uncharacterised protein family UPF0150
HPADDANE_01702	2.88e-56	-	-	-	-	-	-	-	-
HPADDANE_01703	4.76e-65	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Exonuclease, DNA polymerase III, epsilon subunit family
HPADDANE_01704	1.64e-27	-	-	-	-	-	-	-	-
HPADDANE_01705	3.67e-06	-	-	-	-	-	-	-	-
HPADDANE_01712	5.31e-65	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
HPADDANE_01713	1.66e-101	-	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	ParB-like nuclease domain
HPADDANE_01715	1.23e-66	-	-	-	K	-	-	-	Transcriptional regulator
HPADDANE_01717	7.1e-66	-	-	-	V	-	-	-	HNH endonuclease
HPADDANE_01724	3.27e-11	-	-	-	-	-	-	-	-
HPADDANE_01728	2.03e-114	-	-	-	-	-	-	-	-
HPADDANE_01730	1e-50	-	-	-	L	-	-	-	HNH nucleases
HPADDANE_01733	9.48e-280	-	-	-	S	-	-	-	Terminase
HPADDANE_01734	1.83e-78	-	-	-	S	-	-	-	Phage portal protein
HPADDANE_01736	4.61e-121	-	-	-	S	-	-	-	Phage capsid family
HPADDANE_01739	1.68e-39	-	-	-	-	-	-	-	-
HPADDANE_01740	4.03e-36	-	-	-	-	-	-	-	-
HPADDANE_01742	9.43e-74	-	-	-	-	-	-	-	-
HPADDANE_01746	5.11e-26	-	-	-	NT	-	-	-	phage tail tape measure protein
HPADDANE_01747	2.98e-21	-	-	-	M	-	-	-	nuclear chromosome segregation
HPADDANE_01749	1.3e-238	-	-	-	S	-	-	-	cellulase activity
HPADDANE_01754	1.1e-26	-	-	-	-	-	-	-	-
HPADDANE_01755	7.52e-78	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HPADDANE_01756	4.37e-34	-	-	-	S	-	-	-	Putative phage holin Dp-1
HPADDANE_01758	3.96e-228	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	Ppx/GppA phosphatase family
HPADDANE_01759	1.32e-131	-	-	-	S	ko:K09009	-	ko00000	Protein of unknown function (DUF501)
HPADDANE_01760	9.56e-103	-	-	-	D	-	-	-	Septum formation initiator
HPADDANE_01761	3.54e-313	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HPADDANE_01762	2.31e-230	-	-	-	C	-	-	-	Aldo/keto reductase family
HPADDANE_01763	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HPADDANE_01764	7.02e-146	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HPADDANE_01765	1.88e-96	-	-	-	S	-	-	-	PIN domain
HPADDANE_01766	3.46e-50	fnt	-	-	P	ko:K06212,ko:K21993	-	ko00000,ko02000	Formate/nitrite transporter
HPADDANE_01767	2.76e-115	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
HPADDANE_01768	0.0	-	-	-	S	ko:K09118	-	ko00000	Uncharacterised protein family (UPF0182)
HPADDANE_01769	1.07e-264	-	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Glycosyl hydrolase family 3 N-terminal domain protein
HPADDANE_01770	2.79e-176	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HPADDANE_01771	6.47e-130	-	-	-	-	-	-	-	-
HPADDANE_01772	1.01e-291	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HPADDANE_01773	0.0	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HPADDANE_01774	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase N terminus
HPADDANE_01775	1.36e-250	-	-	-	S	-	-	-	Protein of unknown function (DUF1648)
HPADDANE_01776	1.07e-93	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
HPADDANE_01777	3.6e-94	-	-	-	S	-	-	-	ABC-2 family transporter protein
HPADDANE_01778	7.88e-155	-	-	-	S	-	-	-	ABC-2 family transporter protein
HPADDANE_01779	1.17e-220	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HPADDANE_01780	9.53e-76	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
HPADDANE_01781	1.19e-41	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
HPADDANE_01783	3.07e-73	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HPADDANE_01784	8.84e-84	queC	6.3.4.20	-	F	ko:K06920	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HPADDANE_01785	2.71e-151	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HPADDANE_01786	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
HPADDANE_01787	2.51e-239	nadK	2.7.1.23	-	H	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HPADDANE_01788	3.9e-126	-	-	-	-	-	-	-	-
HPADDANE_01789	4.1e-176	tlyA	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
HPADDANE_01791	2.11e-250	-	-	-	G	-	-	-	Haloacid dehalogenase-like hydrolase
HPADDANE_01792	1.36e-223	-	-	-	L	-	-	-	Tetratricopeptide repeat
HPADDANE_01793	0.0	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HPADDANE_01794	2.89e-175	-	-	-	S	-	-	-	Putative ABC-transporter type IV
HPADDANE_01795	3.05e-127	-	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HPADDANE_01796	1.76e-73	-	-	-	P	-	-	-	Rhodanese Homology Domain
HPADDANE_01797	1.14e-188	thiF	2.7.7.73, 2.7.7.80, 2.8.1.11	-	H	ko:K03148,ko:K21147	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	ThiF family
HPADDANE_01798	9.81e-200	thiG	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
HPADDANE_01799	5.91e-38	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	ThiS family
HPADDANE_01800	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
HPADDANE_01801	4.9e-303	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
HPADDANE_01802	4.34e-110	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HPADDANE_01803	7.19e-234	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HPADDANE_01804	4.64e-313	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
HPADDANE_01805	3.68e-212	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
HPADDANE_01806	7.6e-269	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HPADDANE_01807	4.33e-259	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HPADDANE_01808	2.51e-140	-	-	-	-	-	-	-	-
HPADDANE_01809	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Phenylalanyl-tRNA synthetase beta
HPADDANE_01810	1.75e-256	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HPADDANE_01811	1.46e-207	tsnR	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HPADDANE_01812	2.69e-190	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HPADDANE_01813	0.0	ykoD	-	-	P	ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HPADDANE_01814	7.57e-141	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
HPADDANE_01815	0.0	argE	-	-	E	-	-	-	Peptidase dimerisation domain
HPADDANE_01816	3.84e-138	-	-	-	S	-	-	-	Protein of unknown function (DUF3043)
HPADDANE_01817	0.0	lpdA	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HPADDANE_01818	3.12e-177	-	-	-	S	-	-	-	Domain of unknown function (DUF4191)
HPADDANE_01819	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HPADDANE_01820	1.11e-93	-	3.2.1.23, 3.2.1.31	-	G	ko:K01190,ko:K01195	ko00040,ko00052,ko00511,ko00531,ko00600,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00052,map00511,map00531,map00600,map00860,map00944,map00983,map01100,map01110,map04142	ko00000,ko00001,ko00002,ko01000	Glycosyl hydrolases family 2, TIM barrel domain
HPADDANE_01821	4.25e-233	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HPADDANE_01822	1.18e-102	-	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HPADDANE_01823	9.62e-108	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
HPADDANE_01825	0.0	-	-	-	L	-	-	-	PFAM Integrase catalytic
HPADDANE_01826	1.48e-306	-	-	-	V	-	-	-	MatE
HPADDANE_01827	0.0	uvrA3	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HPADDANE_01828	0.0	-	-	-	H	-	-	-	Protein of unknown function (DUF4012)
HPADDANE_01829	9.08e-118	-	-	-	S	ko:K07133	-	ko00000	AAA domain
HPADDANE_01830	7.11e-172	-	-	-	C	-	-	-	FMN binding
HPADDANE_01831	4.96e-123	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HPADDANE_01832	5.1e-07	-	-	-	K	-	-	-	MerR, DNA binding
HPADDANE_01833	0.0	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
HPADDANE_01834	5.76e-244	adh	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
HPADDANE_01835	4.27e-114	-	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HPADDANE_01836	1.04e-73	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HPADDANE_01837	3.13e-80	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HPADDANE_01838	3.55e-237	-	-	-	S	-	-	-	Conserved hypothetical protein 698
HPADDANE_01839	1.49e-185	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
HPADDANE_01840	1.17e-127	tmp1	-	-	S	-	-	-	Domain of unknown function (DUF4391)
HPADDANE_01841	3.37e-292	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HPADDANE_01842	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HPADDANE_01843	1.1e-103	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HPADDANE_01844	1.65e-80	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HPADDANE_01845	8.11e-18	-	-	-	L	-	-	-	Helix-turn-helix domain
HPADDANE_01846	1.89e-110	-	-	-	V	-	-	-	Abi-like protein
HPADDANE_01847	1.17e-230	-	-	-	S	ko:K03453	-	ko00000	SBF-like CPA transporter family (DUF4137)
HPADDANE_01849	2.97e-243	ltaE	4.1.2.48	-	E	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Beta-eliminating lyase
HPADDANE_01850	9.71e-274	-	-	-	M	-	-	-	Glycosyl transferase 4-like domain
HPADDANE_01851	6.24e-241	-	2.6.1.1, 2.6.1.2, 2.6.1.66, 2.6.1.83	-	E	ko:K00812,ko:K08969,ko:K10206,ko:K14260,ko:K14261	ko00220,ko00250,ko00270,ko00290,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
HPADDANE_01852	2.52e-291	purT	2.1.2.2	-	F	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HPADDANE_01853	4.25e-82	gloA	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HPADDANE_01854	9.74e-176	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
HPADDANE_01855	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	CobB/CobQ-like glutamine amidotransferase domain
HPADDANE_01856	5.81e-200	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HPADDANE_01857	0.0	-	-	-	Q	-	-	-	D-alanine [D-alanyl carrier protein] ligase activity
HPADDANE_01858	1.17e-138	-	-	-	Q	-	-	-	D-alanine [D-alanyl carrier protein] ligase activity
HPADDANE_01859	1.09e-128	nnrE	-	-	L	-	-	-	Uracil DNA glycosylase superfamily
HPADDANE_01860	2.14e-215	-	2.7.11.1	-	S	ko:K07154	-	ko00000,ko01000,ko01001,ko02048	HipA N-terminal domain
HPADDANE_01861	2.75e-41	-	-	-	K	-	-	-	Helix-turn-helix
HPADDANE_01862	4.32e-58	-	-	-	C	-	-	-	Aldo/keto reductase family
HPADDANE_01863	1.35e-42	-	-	-	-	-	-	-	-
HPADDANE_01864	0.0	-	-	-	L	ko:K03502	-	ko00000,ko03400	DNA-damage repair protein (DNA polymerase IV) K00961
HPADDANE_01865	8.26e-242	-	3.3.1.1	-	H	ko:K01251	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	S-adenosyl-L-homocysteine hydrolase, NAD binding domain
HPADDANE_01866	4.7e-302	-	-	-	F	-	-	-	Amidohydrolase family
HPADDANE_01867	7.06e-86	-	-	-	S	ko:K09705	-	ko00000	Cupin superfamily (DUF985)
HPADDANE_01868	5.81e-164	-	-	-	ET	ko:K02030,ko:K02424,ko:K17073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Bacterial periplasmic substrate-binding proteins
HPADDANE_01869	4.54e-161	-	-	-	E	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HPADDANE_01870	2.57e-153	-	3.6.3.21	-	E	ko:K02028,ko:K02029	-	ko00000,ko00002,ko01000,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HPADDANE_01871	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HPADDANE_01872	3.72e-239	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
HPADDANE_01873	1.82e-294	purD	6.3.3.1, 6.3.4.13	-	F	ko:K01945,ko:K11788	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
HPADDANE_01874	0.0	aldH	1.2.1.3, 1.2.99.10	-	C	ko:K00128,ko:K22445	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldehyde dehydrogenase family
HPADDANE_01875	0.0	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 9.26
HPADDANE_01876	1.37e-199	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Zinc-uptake complex component A periplasmic
HPADDANE_01877	1.13e-127	-	-	-	S	-	-	-	cobalamin synthesis protein
HPADDANE_01878	8.31e-40	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L28 family
HPADDANE_01879	1.66e-27	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L33
HPADDANE_01880	1.24e-58	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HPADDANE_01881	1.72e-45	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
HPADDANE_01882	4.34e-21	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L36
HPADDANE_01883	1.55e-27	-	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Ribosomal L32p protein family
HPADDANE_01884	1.58e-16	-	-	-	P	ko:K02077,ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
HPADDANE_01885	6.09e-07	-	-	-	P	ko:K02077,ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
HPADDANE_01886	9.76e-241	-	-	-	S	ko:K07089	-	ko00000	Predicted permease
HPADDANE_01887	1.33e-178	-	-	-	S	-	-	-	TIGRFAM TIGR03943 family protein
HPADDANE_01888	3.21e-110	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Ferric uptake regulator family
HPADDANE_01889	3.43e-85	-	-	-	-	-	-	-	-
HPADDANE_01890	9.45e-45	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
HPADDANE_01891	1.28e-32	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HPADDANE_01892	4.08e-92	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HPADDANE_01893	7.7e-95	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
HPADDANE_01894	4.04e-285	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HPADDANE_01895	2.07e-111	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HPADDANE_01896	2.02e-224	yogA	-	-	C	-	-	-	Zinc-binding dehydrogenase
HPADDANE_01897	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HPADDANE_01898	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HPADDANE_01899	3.75e-06	-	-	-	M	-	-	-	Conserved repeat domain
HPADDANE_01900	1.53e-118	-	-	-	M	-	-	-	Conserved repeat domain
HPADDANE_01901	8.14e-157	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HPADDANE_01903	7.12e-275	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
HPADDANE_01904	1.02e-201	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HPADDANE_01905	0.0	-	-	-	G	-	-	-	Alpha-L-arabinofuranosidase C-terminal domain
HPADDANE_01906	1.47e-48	-	-	-	-	-	-	-	-
HPADDANE_01907	0.0	-	-	-	EK	ko:K03710,ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000,ko03000	Alanine-glyoxylate amino-transferase
HPADDANE_01908	5.69e-147	pdxT	4.3.3.6	-	H	ko:K08681	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HPADDANE_01909	1.63e-199	pdxS	4.3.3.6	-	H	ko:K06215	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HPADDANE_01910	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HPADDANE_01911	2.52e-306	dgt	3.1.5.1	-	F	ko:K01129	ko00230,map00230	ko00000,ko00001,ko01000	Phosphohydrolase-associated domain
HPADDANE_01912	2.4e-312	alr	5.1.1.1	-	M	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HPADDANE_01913	0.0	aap1	-	-	E	ko:K03294	-	ko00000	aromatic amino acid transport protein AroP K03293
HPADDANE_01914	1.45e-131	cysE	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HPADDANE_01915	9.65e-120	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HPADDANE_01916	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HPADDANE_01917	0.0	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
HPADDANE_01918	3.88e-284	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
HPADDANE_01919	1.05e-117	cbs	2.5.1.47, 4.2.1.22	-	E	ko:K01697,ko:K01738	ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
HPADDANE_01920	0.000141	-	-	-	F	-	-	-	Amidohydrolase family
HPADDANE_01921	7.91e-225	-	-	-	EGP	ko:K08168	-	ko00000,ko00002,ko01504,ko02000	Major Facilitator Superfamily
HPADDANE_01922	3.26e-192	iunH2	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
HPADDANE_01924	8.49e-157	-	-	-	EP	ko:K02031	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	oligopeptide transport protein of the ABC superfamily, ATP-binding component
HPADDANE_01925	2.96e-181	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HPADDANE_01926	7.96e-206	-	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HPADDANE_01927	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
HPADDANE_01928	6.82e-309	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HPADDANE_01929	4.65e-181	coaX	2.7.1.33	-	H	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HPADDANE_01930	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HPADDANE_01931	0.0	bga1	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
HPADDANE_01932	1.72e-141	-	5.4.99.28, 5.4.99.29	-	J	ko:K06177	-	ko00000,ko01000,ko03009,ko03016	RNA pseudouridylate synthase
HPADDANE_01933	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HPADDANE_01934	1.23e-191	tcyC	3.6.3.21	-	E	ko:K02028,ko:K02029	-	ko00000,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HPADDANE_01935	1.64e-217	yecS	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HPADDANE_01936	1.45e-209	glnH	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter, substrate-binding protein, family 3
HPADDANE_01937	2.33e-212	glnH	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter, substrate-binding protein, family 3
HPADDANE_01938	8.01e-107	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HPADDANE_01939	4.6e-261	-	-	-	D	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	CHAP domain protein
HPADDANE_01940	3.68e-204	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in cellular division
HPADDANE_01941	2.07e-234	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Cell division ATP-binding protein FtsE
HPADDANE_01942	8.81e-264	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HPADDANE_01943	0.0	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
HPADDANE_01944	0.0	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HPADDANE_01945	2.24e-160	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HPADDANE_01946	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HPADDANE_01947	4.53e-131	-	-	-	P	ko:K02025,ko:K05814	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HPADDANE_01948	7.79e-124	-	-	-	G	ko:K02026,ko:K05815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HPADDANE_01949	2.99e-200	-	-	-	G	ko:K05813	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HPADDANE_01950	4.17e-126	-	-	-	C	-	-	-	Domain of unknown function
HPADDANE_01951	0.0	pepN	3.4.11.2	-	E	ko:K01256,ko:K08776	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Peptidase family M1 domain
HPADDANE_01952	0.0	rnj	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HPADDANE_01953	8.94e-213	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HPADDANE_01954	1.26e-167	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HPADDANE_01955	1.76e-296	-	-	-	G	-	-	-	Major Facilitator Superfamily
HPADDANE_01956	0.0	uvrD2	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	Belongs to the helicase family. UvrD subfamily
HPADDANE_01957	0.0	-	-	-	L	-	-	-	PD-(D/E)XK nuclease superfamily
HPADDANE_01958	0.0	pknK	2.7.11.1	-	KLT	ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
HPADDANE_01959	0.0	-	-	-	S	-	-	-	Fibronectin type 3 domain
HPADDANE_01960	6.98e-230	-	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
HPADDANE_01961	1.52e-283	-	-	-	S	-	-	-	Protein of unknown function DUF58
HPADDANE_01962	0.0	-	-	-	E	-	-	-	Transglutaminase-like superfamily
HPADDANE_01963	7.49e-32	-	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	Sigma factor PP2C-like phosphatases
HPADDANE_01964	3.22e-97	-	-	-	B	-	-	-	Belongs to the OprB family
HPADDANE_01965	6.23e-117	-	-	-	T	-	-	-	Forkhead associated domain
HPADDANE_01966	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HPADDANE_01967	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HPADDANE_01968	9.1e-151	-	-	-	-	-	-	-	-
HPADDANE_01969	1.98e-232	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	FES
HPADDANE_01970	3.37e-148	spoU	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HPADDANE_01971	3.82e-52	-	-	-	DJ	ko:K06218	-	ko00000,ko02048	ParE toxin of type II toxin-antitoxin system, parDE
HPADDANE_01972	3.68e-45	-	-	-	S	ko:K18918	-	ko00000,ko02048,ko03000	CopG domain protein DNA-binding domain protein
HPADDANE_01973	3.64e-157	-	-	-	G	ko:K08369	-	ko00000,ko02000	Sugar (and other) transporter
HPADDANE_01974	2.08e-284	-	-	-	M	-	-	-	Belongs to the D-alanine--D-alanine ligase family
HPADDANE_01975	4.25e-71	-	-	-	Q	-	-	-	Peptide synthetase
HPADDANE_01976	6.3e-274	-	-	-	P	-	-	-	Major Facilitator Superfamily
HPADDANE_01977	5.65e-51	-	-	-	S	ko:K06921	-	ko00000	ATPase domain predominantly from Archaea
HPADDANE_01978	7.94e-210	-	-	-	S	ko:K06921	-	ko00000	ATPase domain predominantly from Archaea
HPADDANE_01979	0.0	-	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
HPADDANE_01980	1.13e-58	-	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
HPADDANE_01981	0.0	-	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
HPADDANE_01982	6.68e-242	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HPADDANE_01983	4.41e-146	-	-	-	S	-	-	-	Protein of unknown function, DUF624
HPADDANE_01984	2.26e-216	-	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HPADDANE_01985	2.3e-218	-	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HPADDANE_01986	0.0	-	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HPADDANE_01987	7.18e-298	galK	2.7.1.6, 2.7.7.12	-	G	ko:K00849,ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GHMP kinase family. GalK subfamily
HPADDANE_01988	0.0	galT	2.7.7.12	-	C	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	Galactose-1-phosphate uridyl transferase, N-terminal domain
HPADDANE_01989	6.97e-156	-	-	-	K	-	-	-	DeoR C terminal sensor domain
HPADDANE_01990	8.47e-287	pyrD	1.3.5.2, 1.3.98.1	-	F	ko:K00226,ko:K00254	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
HPADDANE_01991	1e-315	namA	-	-	C	-	-	-	NADH:flavin oxidoreductase / NADH oxidase family
HPADDANE_01992	0.0	pon1	-	-	M	-	-	-	Transglycosylase
HPADDANE_01993	1.23e-168	crp	-	-	K	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
HPADDANE_01994	1.74e-252	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Biotin/lipoate A/B protein ligase family
HPADDANE_01995	3.1e-246	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HPADDANE_01996	0.0	ptrB	3.4.21.83	-	E	ko:K01354	ko05142,ko05143,map05142,map05143	ko00000,ko00001,ko01000,ko01002	Peptidase, S9A B C family, catalytic domain protein
HPADDANE_01997	0.0	-	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2183)
HPADDANE_01998	7.9e-92	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
HPADDANE_01999	5.88e-295	nudC	3.6.1.22	-	L	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	ko00000,ko00001,ko01000	NADH pyrophosphatase zinc ribbon domain
HPADDANE_02000	9.92e-207	-	-	-	I	-	-	-	Alpha/beta hydrolase family
HPADDANE_02001	1.77e-163	-	-	-	F	-	-	-	Domain of unknown function (DUF4916)
HPADDANE_02002	5.55e-79	trxA	1.8.1.9	-	O	ko:K00384,ko:K03671	ko00450,ko04621,ko05418,map00450,map04621,map05418	ko00000,ko00001,ko01000,ko03110	Belongs to the thioredoxin family
HPADDANE_02003	1.04e-220	-	-	-	S	ko:K21688	-	ko00000	G5
HPADDANE_02004	8.23e-26	-	-	-	K	ko:K15773	-	ko00000,ko02048,ko03000	Helix-turn-helix XRE-family like proteins
HPADDANE_02005	2.29e-165	-	2.7.11.1	-	S	ko:K07154	-	ko00000,ko01000,ko01001,ko02048	HipA-like C-terminal domain
HPADDANE_02006	7.39e-238	-	-	-	-	-	-	-	-
HPADDANE_02007	1.9e-313	wcoI	-	-	DM	-	-	-	Psort location CytoplasmicMembrane, score
HPADDANE_02008	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
HPADDANE_02009	1.29e-13	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
HPADDANE_02010	3.65e-29	-	-	-	S	-	-	-	enterobacterial common antigen metabolic process
HPADDANE_02011	1.39e-235	-	-	-	S	ko:K06926	-	ko00000	AAA domain, putative AbiEii toxin, Type IV TA system
HPADDANE_02012	7.68e-115	-	-	-	S	-	-	-	RloB-like protein
HPADDANE_02014	1.29e-128	-	-	-	J	-	-	-	tRNA cytidylyltransferase activity
HPADDANE_02015	1.1e-18	-	-	-	L	-	-	-	Transposase
HPADDANE_02016	4.25e-38	-	-	-	L	-	-	-	Transposase
HPADDANE_02018	1.57e-259	-	-	-	L	ko:K03733	-	ko00000,ko03036	Phage integrase, N-terminal SAM-like domain
HPADDANE_02019	9.21e-246	-	-	-	L	-	-	-	Phage integrase family
HPADDANE_02020	1.12e-286	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HPADDANE_02021	2.93e-13	-	-	-	S	-	-	-	Abi-like protein
HPADDANE_02023	1.7e-108	-	-	-	S	-	-	-	AAA ATPase domain
HPADDANE_02024	3.85e-20	-	-	-	S	-	-	-	AAA ATPase domain
HPADDANE_02025	1.59e-86	-	2.1.1.72	-	L	ko:K06223	ko03430,map03430	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	PFAM D12 class N6 adenine-specific DNA methyltransferase
HPADDANE_02026	2.79e-150	-	-	-	L	ko:K07485	-	ko00000	Transposase
HPADDANE_02027	1.45e-63	istB	-	-	L	-	-	-	IstB-like ATP binding protein
HPADDANE_02028	6.96e-305	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
HPADDANE_02030	3.51e-117	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HPADDANE_02031	4.5e-112	-	-	-	H	-	-	-	Core-2/I-Branching enzyme
HPADDANE_02032	2.02e-35	-	-	-	M	-	-	-	Capsular polysaccharide synthesis protein
HPADDANE_02033	9.74e-35	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HPADDANE_02034	1.54e-117	-	-	GT4	M	ko:K19424	-	ko00000,ko01000,ko01003	Psort location Cytoplasmic, score 8.87
HPADDANE_02037	1.44e-110	-	-	-	M	-	-	-	Domain of unknown function (DUF4422)
HPADDANE_02038	1.94e-73	-	-	-	L	-	-	-	Helix-turn-helix domain
HPADDANE_02039	1.46e-139	etp	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Low molecular weight phosphatase family
HPADDANE_02040	0.0	rfbP	-	-	M	-	-	-	Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
HPADDANE_02042	2.38e-77	-	-	-	-	-	-	-	-
HPADDANE_02043	1.15e-24	-	-	-	L	-	-	-	Transposase
HPADDANE_02044	1.49e-198	-	-	-	S	-	-	-	AAA ATPase domain
HPADDANE_02045	2.96e-35	-	-	-	S	-	-	-	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HPADDANE_02046	0.0	bga1	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
HPADDANE_02047	0.0	pafA	6.3.1.19	-	O	ko:K13571	-	ko00000,ko00002,ko01000,ko03051	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
HPADDANE_02048	1.91e-24	pup	-	-	S	ko:K13570	-	ko00000,ko04121	Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
HPADDANE_02049	4.77e-216	-	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase family
HPADDANE_02050	0.0	dop	3.5.1.119	-	S	ko:K20814	-	ko00000,ko01000,ko03051	Pup-ligase protein
HPADDANE_02051	0.0	arc	-	-	O	ko:K13527	ko03050,map03050	ko00000,ko00001,ko00002,ko03051	AAA ATPase forming ring-shaped complexes
HPADDANE_02052	5.22e-162	-	-	-	S	-	-	-	SNARE associated Golgi protein
HPADDANE_02053	2.89e-163	serB	3.1.3.3	-	E	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01009	haloacid dehalogenase-like hydrolase
HPADDANE_02054	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HPADDANE_02055	3.56e-170	-	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HPADDANE_02056	1.14e-229	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HPADDANE_02057	0.0	ilvD	4.2.1.9	-	H	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the IlvD Edd family
HPADDANE_02058	1.34e-61	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HPADDANE_02059	2.77e-290	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HPADDANE_02060	5.93e-287	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HPADDANE_02061	5.09e-266	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Efflux ABC transporter, permease protein
HPADDANE_02062	6.89e-143	vex	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HPADDANE_02063	2.08e-127	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	low molecular weight
HPADDANE_02064	6.93e-161	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	dihydrofolate reductase
HPADDANE_02066	9.68e-221	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HPADDANE_02067	9.14e-96	-	-	-	O	-	-	-	OsmC-like protein
HPADDANE_02068	3.06e-238	-	-	-	T	-	-	-	Universal stress protein family
HPADDANE_02069	3.13e-138	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
HPADDANE_02070	1.6e-123	-	-	-	M	-	-	-	NlpC/P60 family
HPADDANE_02071	1.45e-211	-	-	-	S	-	-	-	CHAP domain
HPADDANE_02073	9.65e-271	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HPADDANE_02074	1.97e-50	-	-	-	-	-	-	-	-
HPADDANE_02075	2.64e-253	senX3	2.7.13.3	-	T	ko:K07768	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HPADDANE_02076	6.05e-148	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
HPADDANE_02077	3.69e-178	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HPADDANE_02081	3.6e-20	-	-	-	-	-	-	-	-
HPADDANE_02082	1.04e-182	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the MenA family. Type 1 subfamily
HPADDANE_02083	1.62e-28	-	-	-	T	-	-	-	Histidine kinase
HPADDANE_02084	3.61e-38	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
HPADDANE_02088	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HPADDANE_02090	1.7e-263	-	-	-	EGP	ko:K08156,ko:K19577	-	ko00000,ko02000	Major Facilitator Superfamily
HPADDANE_02091	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4037)
HPADDANE_02092	9.45e-145	-	-	-	S	-	-	-	Protein of unknown function (DUF4125)
HPADDANE_02093	0.0	-	-	-	S	ko:K06889	-	ko00000	alpha beta
HPADDANE_02094	1.36e-98	-	-	-	-	-	-	-	-
HPADDANE_02095	3.76e-235	pspC	-	-	KT	-	-	-	PspC domain
HPADDANE_02096	3.43e-287	tcsS3	-	-	KT	-	-	-	PspC domain
HPADDANE_02097	1.17e-143	tcsR3	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
HPADDANE_02098	1.7e-237	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HPADDANE_02099	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
HPADDANE_02100	1.78e-244	-	2.7.1.162	-	S	ko:K13059	-	ko00000,ko01000	Phosphotransferase enzyme family
HPADDANE_02101	0.0	gnpA	2.4.1.211	-	S	ko:K15533	-	ko00000,ko01000	Lacto-N-biose phosphorylase C-terminal domain
HPADDANE_02103	1.79e-304	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HPADDANE_02104	4.92e-266	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HPADDANE_02105	4e-203	arbG	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HPADDANE_02106	0.0	ptsG	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system, glucose-specific IIABC component
HPADDANE_02107	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
HPADDANE_02108	1.08e-239	-	-	-	S	-	-	-	Protein conserved in bacteria
HPADDANE_02109	3.69e-90	-	-	-	K	-	-	-	Transcriptional regulator
HPADDANE_02110	0.0	merA	1.16.1.1	-	C	ko:K00520,ko:K21739	-	ko00000,ko01000	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HPADDANE_02112	3.98e-188	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HPADDANE_02113	7.11e-160	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HPADDANE_02114	5.05e-07	-	-	-	S	-	-	-	Mitochondrial domain of unknown function (DUF1713)
HPADDANE_02116	1.93e-128	-	-	-	-	-	-	-	-
HPADDANE_02117	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HPADDANE_02118	1.96e-276	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	riboflavin kinase
HPADDANE_02119	1.67e-270	truB	5.4.99.25	-	J	ko:K03177	-	ko00000,ko01000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HPADDANE_02120	5.22e-96	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HPADDANE_02121	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HPADDANE_02122	2.08e-241	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HPADDANE_02123	4.58e-161	-	-	-	-	-	-	-	-
HPADDANE_02124	2.88e-310	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HPADDANE_02125	3.1e-221	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HPADDANE_02126	3.29e-205	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HPADDANE_02127	2.94e-17	-	-	-	L	-	-	-	Integrase core domain
HPADDANE_02129	4.23e-275	-	-	-	S	ko:K07133	-	ko00000	Psort location Cytoplasmic, score
HPADDANE_02130	2.94e-194	-	-	-	E	-	-	-	Transglutaminase/protease-like homologues
HPADDANE_02131	0.0	gcs2	-	-	S	ko:K06048	-	ko00000,ko01000	A circularly permuted ATPgrasp
HPADDANE_02132	3.9e-213	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HPADDANE_02133	8.8e-84	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HPADDANE_02134	4.01e-236	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HPADDANE_02135	7.34e-86	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HPADDANE_02136	1.16e-81	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HPADDANE_02137	1.47e-20	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
HPADDANE_02138	6.91e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HPADDANE_02139	7.36e-128	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HPADDANE_02140	0.0	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HPADDANE_02141	1.52e-98	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
HPADDANE_02142	4.64e-36	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30p/L7e
HPADDANE_02143	2.82e-128	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HPADDANE_02144	3.43e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HPADDANE_02145	7.72e-122	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HPADDANE_02146	3.17e-90	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HPADDANE_02147	7.06e-40	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HPADDANE_02148	2.77e-134	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HPADDANE_02149	1.09e-68	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HPADDANE_02150	2.55e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HPADDANE_02151	1.11e-54	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HPADDANE_02152	1.97e-49	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
HPADDANE_02153	3.85e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HPADDANE_02154	1.32e-161	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HPADDANE_02155	1.55e-74	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HPADDANE_02156	1.4e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HPADDANE_02157	1.34e-195	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HPADDANE_02158	3.61e-61	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HPADDANE_02159	1.97e-150	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
HPADDANE_02160	1.57e-149	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HPADDANE_02161	9.35e-68	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
HPADDANE_02162	2.4e-183	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
HPADDANE_02163	0.0	adhE	1.1.1.1, 1.2.1.10, 1.2.1.81	-	C	ko:K04072,ko:K15515	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
HPADDANE_02164	1.53e-278	-	-	-	GK	-	-	-	transcriptional repressor of nag (N-acetylglucosamine) operon K02565
HPADDANE_02166	6.54e-87	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HPADDANE_02167	1.93e-283	csbX	-	-	EGP	-	-	-	Major Facilitator Superfamily
HPADDANE_02168	5.33e-222	-	1.1.1.1, 1.1.1.287, 1.6.5.5	-	C	ko:K00001,ko:K00344,ko:K17818	ko00010,ko00040,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00040,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
HPADDANE_02169	0.0	glgX	3.2.1.196, 3.2.1.68	CBM48,GH13	G	ko:K01214,ko:K02438	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 13 family
HPADDANE_02170	9.6e-106	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
HPADDANE_02171	3.75e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HPADDANE_02172	2.49e-231	malQ	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	4-alpha-glucanotransferase
HPADDANE_02173	1.26e-239	malQ	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	4-alpha-glucanotransferase
HPADDANE_02174	7.39e-140	-	-	-	-	-	-	-	-
HPADDANE_02175	1.28e-139	yigZ	-	-	S	-	-	-	Uncharacterized protein family UPF0029
HPADDANE_02176	1.25e-238	pdxB	-	-	EH	-	-	-	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HPADDANE_02178	0.000454	-	-	-	S	ko:K11939	-	ko00000,ko02000	EamA-like transporter family
HPADDANE_02179	3.34e-298	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HPADDANE_02180	4.38e-285	dapC	-	-	E	-	-	-	Aminotransferase class I and II
HPADDANE_02181	1.57e-79	fdxA	-	-	C	ko:K05524	-	ko00000	4Fe-4S binding domain
HPADDANE_02182	0.0	-	-	-	E	ko:K03294	-	ko00000	aromatic amino acid transport protein AroP K03293
HPADDANE_02183	2.75e-286	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
HPADDANE_02184	1.03e-34	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L33
HPADDANE_02188	8.21e-51	megL	4.4.1.11	-	E	ko:K01761	ko00270,ko00450,map00270,map00450	ko00000,ko00001,ko01000	Cys/Met metabolism PLP-dependent enzyme
HPADDANE_02189	6.02e-64	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HPADDANE_02190	2.6e-281	-	-	-	-	-	-	-	-
HPADDANE_02191	2.42e-166	rimJ	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HPADDANE_02192	7.89e-167	ygfA	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	5-formyltetrahydrofolate cyclo-ligase family
HPADDANE_02193	1.26e-42	-	-	-	S	-	-	-	Putative regulatory protein
HPADDANE_02194	5.03e-121	-	-	-	NO	-	-	-	SAF
HPADDANE_02195	2.09e-41	-	-	-	-	-	-	-	-
HPADDANE_02196	0.0	-	-	-	L	-	-	-	Superfamily I DNA and RNA helicases and helicase subunits
HPADDANE_02197	5.42e-248	-	-	-	T	-	-	-	Forkhead associated domain
HPADDANE_02198	6.07e-64	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HPADDANE_02199	2.41e-113	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HPADDANE_02200	1.58e-178	-	-	-	S	-	-	-	alpha beta
HPADDANE_02201	1.58e-314	-	-	-	S	ko:K06901	-	ko00000,ko02000	Permease family
HPADDANE_02202	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HPADDANE_02203	1.44e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HPADDANE_02204	1.89e-240	-	-	-	V	-	-	-	ABC transporter
HPADDANE_02205	3.58e-198	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
HPADDANE_02210	4.52e-171	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
HPADDANE_02211	2.46e-149	-	-	-	-	-	-	-	-
HPADDANE_02212	4.19e-64	-	-	-	-	-	-	-	-
HPADDANE_02214	2.44e-53	-	-	-	M	-	-	-	domain protein
HPADDANE_02215	1.68e-60	-	-	-	M	-	-	-	LPXTG cell wall anchor motif
HPADDANE_02216	0.0	-	-	-	M	-	-	-	Conserved repeat domain
HPADDANE_02217	2.02e-102	-	-	-	-	-	-	-	-
HPADDANE_02220	3.44e-16	dexB	2.4.1.7, 3.2.1.20, 3.2.1.51, 3.2.1.70, 3.2.1.93, 3.2.1.97	GH101,GH13,GH29,GH31	G	ko:K00690,ko:K01187,ko:K01206,ko:K01215,ko:K01226,ko:K17624	ko00052,ko00500,ko00511,ko01100,map00052,map00500,map00511,map01100	ko00000,ko00001,ko01000,ko04147	hydrolase activity, hydrolyzing O-glycosyl compounds
HPADDANE_02221	2.58e-126	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HPADDANE_02222	0.0	fas	-	-	I	ko:K11533	ko00061,ko01100,ko01212,ko04931,map00061,map01100,map01212,map04931	ko00000,ko00001,ko00002,ko01000,ko01004	Beta-ketoacyl synthase, C-terminal domain
HPADDANE_02223	0.0	pccB	-	-	I	-	-	-	Carboxyl transferase domain
HPADDANE_02224	0.0	accC	6.3.4.14, 6.4.1.2, 6.4.1.3	-	I	ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase L chain, ATP binding domain protein
HPADDANE_02225	5.66e-17	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
HPADDANE_02226	3.48e-188	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Biotin/lipoate A/B protein ligase family
HPADDANE_02227	0.0	-	-	-	-	-	-	-	-
HPADDANE_02228	1.89e-177	-	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
HPADDANE_02229	2.05e-30	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HPADDANE_02230	1.07e-146	-	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transketolase, pyrimidine binding domain
HPADDANE_02231	2.31e-135	-	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
HPADDANE_02232	0.0	ppdK	2.7.9.1	-	G	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the PEP-utilizing enzyme family
HPADDANE_02233	2.43e-173	-	-	-	EGP	ko:K06609	-	ko00000,ko02000	Sugar (and other) transporter
HPADDANE_02235	2.02e-145	-	-	-	EGP	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HPADDANE_02236	2.75e-162	iolE	4.2.1.44	-	G	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	dehydratase
HPADDANE_02237	1e-175	iolG	1.1.1.18, 1.1.1.369	-	C	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
HPADDANE_02238	1.19e-129	idhA	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
HPADDANE_02239	5.43e-56	-	-	-	K	ko:K13633	-	ko00000,ko03000	Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain
HPADDANE_02240	3e-200	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HPADDANE_02241	1.4e-107	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HPADDANE_02242	9.14e-96	-	-	-	K	-	-	-	Sugar-specific transcriptional regulator TrmB
HPADDANE_02243	1.5e-75	-	-	-	K	-	-	-	Bacterial transcriptional regulator
HPADDANE_02244	9.24e-261	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Aldehyde dehydrogenase family
HPADDANE_02245	1.17e-203	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Alcohol dehydrogenase GroES-like domain
HPADDANE_02246	1.93e-164	iolB	5.3.1.30	-	G	ko:K03337	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	PFAM Myo-inositol catabolism IolB domain protein
HPADDANE_02247	0.0	-	-	-	E	-	-	-	Thiamine pyrophosphate enzyme, central domain
HPADDANE_02248	2.45e-39	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
HPADDANE_02249	2.68e-37	-	-	-	S	-	-	-	Unextendable partial coding region
HPADDANE_02250	3.53e-159	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HPADDANE_02251	2.38e-94	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HPADDANE_02252	6.95e-188	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HPADDANE_02253	2.45e-44	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HPADDANE_02255	6.53e-291	aspC	2.6.1.1, 2.6.1.2, 2.6.1.66	-	E	ko:K00812,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	DegT/DnrJ/EryC1/StrS aminotransferase family
HPADDANE_02256	1.65e-253	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HPADDANE_02257	0.0	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HPADDANE_02258	3.99e-53	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L27 protein
HPADDANE_02259	4.13e-62	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
HPADDANE_02260	0.0	rne	3.1.26.12	-	J	ko:K08300,ko:K08301	ko03018,map03018	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	Ribonuclease E/G family
HPADDANE_02261	2.34e-290	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Peptidase dimerisation domain
HPADDANE_02262	3.06e-211	-	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
HPADDANE_02263	9.59e-101	fucU	5.1.3.29	-	G	ko:K02431	-	ko00000,ko01000	RbsD / FucU transport protein family
HPADDANE_02264	1.91e-189	-	-	-	S	ko:K07046	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Amidohydrolase
HPADDANE_02265	2.55e-263	fucP	-	-	G	ko:K02429	-	ko00000,ko02000	Major Facilitator Superfamily
HPADDANE_02266	1.74e-180	-	1.1.1.100, 1.1.1.413	-	IQ	ko:K00059,ko:K18333,ko:K22322	ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01120,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	KR domain
HPADDANE_02267	4.82e-313	-	4.2.1.68	-	M	ko:K18334	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Enolase C-terminal domain-like
HPADDANE_02268	2.48e-231	-	-	-	K	ko:K02529	-	ko00000,ko03000	Bacterial regulatory proteins, lacI family
HPADDANE_02269	0.0	-	-	-	V	-	-	-	Efflux ABC transporter, permease protein
HPADDANE_02270	4.14e-183	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HPADDANE_02272	0.0	maf	-	-	DF	ko:K06287	-	ko00000	Maf-like protein
HPADDANE_02273	1.02e-260	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HPADDANE_02274	5.44e-295	hom	1.1.1.3, 2.7.2.4	-	E	ko:K00003,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
HPADDANE_02275	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HPADDANE_02276	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
HPADDANE_02277	3.78e-219	-	-	-	K	-	-	-	LysR substrate binding domain protein
HPADDANE_02278	2.99e-311	-	4.4.1.8	-	E	ko:K00842,ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I II
HPADDANE_02279	0.0	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HPADDANE_02280	0.0	nox	-	-	C	-	-	-	Pyridine nucleotide-disulphide oxidoreductase
HPADDANE_02281	3.08e-141	-	-	-	L	-	-	-	Putative transposase DNA-binding domain
HPADDANE_02282	1.55e-97	-	-	-	L	-	-	-	Resolvase, N terminal domain
HPADDANE_02283	1.4e-264	pyr	1.3.98.1	-	F	ko:K00226	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Dihydroorotate dehydrogenase
HPADDANE_02284	2.22e-169	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HPADDANE_02285	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HPADDANE_02286	5.17e-179	ltbR	-	-	K	-	-	-	Transcriptional regulator, IclR family, C-terminal domain protein
HPADDANE_02287	5.29e-307	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HPADDANE_02288	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HPADDANE_02289	7.6e-289	mutT	3.6.1.55	-	LT	ko:K03574	-	ko00000,ko01000,ko03400	Phosphoglycerate mutase family
HPADDANE_02290	4.69e-174	-	-	-	-	-	-	-	-
HPADDANE_02291	2.79e-296	gph	-	-	G	ko:K16209	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HPADDANE_02292	0.0	gph	-	-	G	ko:K16209	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HPADDANE_02293	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
HPADDANE_02294	0.0	-	3.2.1.51	GH95	G	ko:K15923	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65, N-terminal domain
HPADDANE_02295	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
HPADDANE_02296	1.26e-90	fucU	5.1.3.29	-	G	ko:K02431	-	ko00000,ko01000	RbsD / FucU transport protein family
HPADDANE_02297	2.56e-195	-	4.1.2.28	-	EM	ko:K22397	ko00040,map00040	ko00000,ko00001,ko01000	Dihydrodipicolinate synthetase family
HPADDANE_02298	3.51e-180	-	1.1.1.100, 1.1.1.413	-	IQ	ko:K00059,ko:K18333,ko:K22322	ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01120,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	KR domain
HPADDANE_02299	2.28e-310	-	4.2.1.68	-	M	ko:K18334	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Enolase C-terminal domain-like
HPADDANE_02300	5.99e-123	-	-	-	S	-	-	-	Protein of unknown function, DUF624
HPADDANE_02301	9.76e-195	-	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HPADDANE_02302	7.69e-193	-	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HPADDANE_02303	1.29e-276	-	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HPADDANE_02304	9.76e-195	-	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HPADDANE_02305	7.69e-193	-	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HPADDANE_02306	1.56e-295	-	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HPADDANE_02307	1.51e-149	-	3.2.1.18	GH33	G	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	ko00000,ko00001,ko01000,ko02042	BNR repeat-like domain
HPADDANE_02308	1.75e-173	nanA	4.1.3.3, 4.3.3.7	-	EM	ko:K01639,ko:K01714	ko00261,ko00300,ko00520,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map00520,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Dihydrodipicolinate synthetase family
HPADDANE_02309	1.57e-314	-	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HPADDANE_02310	3.03e-282	-	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HPADDANE_02311	1.4e-277	-	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HPADDANE_02312	2.85e-247	-	-	-	G	-	-	-	Glycosyl hydrolase family 20, domain 2
HPADDANE_02313	4.87e-37	-	-	-	S	-	-	-	phosphoglycolate phosphatase activity
HPADDANE_02314	1.21e-174	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Extracellular solute-binding protein
HPADDANE_02315	4.68e-143	-	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Metallo-beta-lactamase superfamily
HPADDANE_02316	1.21e-127	-	-	-	P	ko:K02026,ko:K05815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HPADDANE_02317	8.71e-129	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	PFAM Binding-protein-dependent transport system inner membrane component
HPADDANE_02318	1.22e-161	-	-	-	P	ko:K10112,ko:K17240	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HPADDANE_02319	7.52e-121	-	-	-	S	-	-	-	Protein of unknown function (DUF1706)
HPADDANE_02320	6.4e-149	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HPADDANE_02321	6.55e-102	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HPADDANE_02322	4.19e-129	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
HPADDANE_02323	2.66e-261	-	-	-	G	ko:K02027,ko:K17329	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HPADDANE_02324	6.87e-161	-	-	-	G	ko:K02026,ko:K05815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HPADDANE_02325	1.95e-166	-	-	-	P	ko:K02025,ko:K05814	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HPADDANE_02326	8.64e-199	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
HPADDANE_02327	1.37e-198	gluQ	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HPADDANE_02328	0.0	clpB	-	-	O	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HPADDANE_02329	1.96e-96	-	2.3.1.57	-	K	ko:K03826,ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HPADDANE_02330	4.9e-201	-	-	-	Q	-	-	-	Fumarylacetoacetate (FAA) hydrolase family
HPADDANE_02331	2.65e-32	-	-	-	S	-	-	-	Domain of unknown function (DUF4190)
HPADDANE_02332	3.74e-282	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
HPADDANE_02333	7.52e-226	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 5 (cellulase A) family
HPADDANE_02334	6.66e-161	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HPADDANE_02335	9.65e-154	-	-	-	G	ko:K02025,ko:K17330	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HPADDANE_02336	2.91e-220	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HPADDANE_02337	1.12e-217	-	-	-	M	-	-	-	Glycosyl transferase family 2
HPADDANE_02338	4.88e-211	-	-	-	I	-	-	-	Acyltransferase family
HPADDANE_02339	0.0	-	-	-	-	-	-	-	-
HPADDANE_02340	3.24e-193	-	-	-	-	-	-	-	-
HPADDANE_02341	0.0	-	-	-	M	-	-	-	Glycosyl transferase family 8
HPADDANE_02342	7.82e-215	-	-	-	GM	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HPADDANE_02343	1.23e-172	tagG	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
HPADDANE_02344	0.0	-	-	-	M	-	-	-	Glycosyl transferase family 8
HPADDANE_02345	1.84e-299	ugd	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	UDP binding domain
HPADDANE_02346	1.67e-255	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HPADDANE_02347	1.04e-259	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
HPADDANE_02348	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF4012)
HPADDANE_02349	1.6e-291	-	-	-	V	-	-	-	ABC transporter permease
HPADDANE_02350	1.99e-242	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HPADDANE_02351	1.76e-170	-	-	-	T	ko:K06950	-	ko00000	HD domain
HPADDANE_02352	1.2e-203	-	-	-	S	-	-	-	Glutamine amidotransferase domain
HPADDANE_02353	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HPADDANE_02354	1.29e-235	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	TatD related DNase
HPADDANE_02356	2.53e-195	-	-	-	I	-	-	-	Hydrolase, alpha beta domain protein
HPADDANE_02357	1.5e-154	gtr	-	-	U	ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Sugar (and other) transporter
HPADDANE_02358	3.02e-78	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HPADDANE_02359	1.45e-114	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HPADDANE_02360	2.65e-33	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HPADDANE_02361	2.48e-134	-	-	-	K	-	-	-	Fic/DOC family
HPADDANE_02362	4.08e-22	-	-	-	L	-	-	-	HTH-like domain
HPADDANE_02363	1.54e-248	-	-	-	S	-	-	-	Fic/DOC family
HPADDANE_02364	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HPADDANE_02365	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HPADDANE_02366	0.0	-	-	-	S	ko:K06921	-	ko00000	ATPase domain predominantly from Archaea
HPADDANE_02368	0.0	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
HPADDANE_02369	5.79e-76	-	-	-	G	-	-	-	domain, Protein
HPADDANE_02370	0.0	-	-	-	S	ko:K07133	-	ko00000	AAA domain
HPADDANE_02371	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HPADDANE_02373	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HPADDANE_02374	0.0	oppD	-	-	P	ko:K02031,ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HPADDANE_02375	4.98e-226	oppC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	N-terminal TM domain of oligopeptide transport permease C
HPADDANE_02376	1.67e-226	oppB1	-	-	EP	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HPADDANE_02377	0.0	-	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HPADDANE_02378	1.81e-218	-	-	-	S	-	-	-	Protein conserved in bacteria
HPADDANE_02379	2.09e-60	-	-	-	-	-	-	-	-
HPADDANE_02380	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HPADDANE_02381	5.09e-148	-	-	-	-	-	-	-	-
HPADDANE_02382	4.22e-233	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HPADDANE_02384	4.48e-197	-	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HPADDANE_02385	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
HPADDANE_02386	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HPADDANE_02387	2.11e-101	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HPADDANE_02388	0.0	-	-	-	E	ko:K03293	-	ko00000	Amino acid permease
HPADDANE_02389	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HPADDANE_02390	3.65e-158	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HPADDANE_02391	0.0	aroP	-	-	E	ko:K03293,ko:K11732	-	ko00000,ko02000	aromatic amino acid transport protein AroP K03293
HPADDANE_02392	1.12e-132	-	-	-	S	-	-	-	Protein of unknown function, DUF624
HPADDANE_02393	1.83e-195	-	-	-	G	ko:K02026,ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HPADDANE_02394	1.57e-198	msmF	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HPADDANE_02395	7.73e-233	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HPADDANE_02396	3.25e-315	amyE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HPADDANE_02397	3.42e-174	gpm2	3.1.3.73	-	G	ko:K02226	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Phosphoglycerate mutase family
HPADDANE_02398	2.62e-78	-	-	-	S	-	-	-	Protein of unknown function (DUF4235)
HPADDANE_02399	2.58e-180	nfrA	-	-	C	-	-	-	Nitroreductase family
HPADDANE_02400	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
HPADDANE_02401	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
HPADDANE_02402	2.68e-37	-	-	-	S	-	-	-	Unextendable partial coding region
HPADDANE_02403	2.72e-187	cobB2	-	-	K	ko:K12410	-	ko00000,ko01000	Sir2 family
HPADDANE_02404	4.32e-297	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
HPADDANE_02405	0.0	-	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HPADDANE_02406	2.21e-12	-	-	-	L	-	-	-	Transposase
HPADDANE_02407	8.34e-196	-	-	-	G	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HPADDANE_02408	5.6e-206	-	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HPADDANE_02409	6.31e-310	-	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HPADDANE_02410	2.36e-289	-	-	-	GK	-	-	-	ROK family
HPADDANE_02411	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Glycosyl hydrolase family 36 N-terminal domain
HPADDANE_02412	3.4e-106	tadA	3.5.4.1, 3.5.4.33	-	FJ	ko:K01485,ko:K11991	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HPADDANE_02413	0.0	nhaP	-	-	P	ko:K03316	-	ko00000	Sodium/hydrogen exchanger family
HPADDANE_02414	1.25e-188	-	-	-	S	ko:K06999	-	ko00000	Phospholipase/Carboxylesterase
HPADDANE_02415	1.06e-174	-	-	-	-	-	-	-	-
HPADDANE_02416	4.97e-143	dcd	3.5.4.13	-	F	ko:K01494	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dCTP deaminase family
HPADDANE_02417	6.29e-187	-	-	-	-	-	-	-	-
HPADDANE_02418	0.0	pacL2	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
HPADDANE_02419	1.55e-20	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HPADDANE_02420	8.76e-110	-	2.7.1.208	-	G	ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HPADDANE_02421	0.0	nagE	2.7.1.193	-	G	ko:K02802,ko:K02803,ko:K02804	ko00520,ko02060,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HPADDANE_02422	1.08e-270	-	-	-	EGP	-	-	-	Transmembrane secretion effector
HPADDANE_02423	2.64e-220	rlmB	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HPADDANE_02424	0.0	-	-	-	KLT	-	-	-	Domain of unknown function (DUF4032)
HPADDANE_02425	1.47e-267	ugpC	-	-	E	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HPADDANE_02426	3.15e-277	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HPADDANE_02427	2.09e-242	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HPADDANE_02429	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HPADDANE_02430	3.71e-104	nrdI	-	-	F	ko:K03647	-	ko00000	Probably involved in ribonucleotide reductase function
HPADDANE_02431	1.62e-57	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
HPADDANE_02432	8.3e-142	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HPADDANE_02433	8.68e-156	-	-	-	S	-	-	-	Protein of unknown function (DUF3990)
HPADDANE_02434	2.73e-160	-	-	-	U	ko:K10716	-	ko00000,ko02000	Ion channel
HPADDANE_02435	8.76e-261	-	-	-	S	-	-	-	AAA ATPase domain
HPADDANE_02436	0.0	-	-	-	KLT	-	-	-	Protein tyrosine kinase
HPADDANE_02437	5.98e-203	-	-	-	O	-	-	-	Thioredoxin
HPADDANE_02439	5.01e-278	rpfB	-	-	S	ko:K21688	-	ko00000	G5
HPADDANE_02440	2.74e-213	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HPADDANE_02441	2.19e-221	ispE	2.7.1.148	-	F	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HPADDANE_02442	1.7e-142	-	-	-	S	-	-	-	LytR cell envelope-related transcriptional attenuator
HPADDANE_02443	0.0	pcnA	2.7.7.19, 2.7.7.72	-	J	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	Probable RNA and SrmB- binding site of polymerase A
HPADDANE_02444	7.85e-261	mutT4	-	-	L	-	-	-	Belongs to the Nudix hydrolase family
HPADDANE_02445	0.0	-	-	-	-	-	-	-	-
HPADDANE_02446	0.0	mviN	-	-	KLT	ko:K03980	-	ko00000,ko01011,ko02000	MviN-like protein
HPADDANE_02447	1.06e-235	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HPADDANE_02448	5.32e-289	parB	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HPADDANE_02449	1.49e-227	parA	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
HPADDANE_02450	2.41e-157	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
HPADDANE_02451	2.49e-117	jag	-	-	S	ko:K06346	-	ko00000	Putative single-stranded nucleic acids-binding domain
HPADDANE_02452	1.04e-224	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Membrane protein insertase, YidC Oxa1 family
HPADDANE_02453	1e-45	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HPADDANE_02454	3.25e-20	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
HPADDANE_02455	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HPADDANE_02456	6.2e-264	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HPADDANE_02457	4.43e-290	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HPADDANE_02458	6.62e-105	-	-	-	S	-	-	-	Protein of unknown function (DUF721)
HPADDANE_02459	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HPADDANE_02460	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HPADDANE_02461	1.08e-105	-	-	-	S	-	-	-	Transmembrane domain of unknown function (DUF3566)
HPADDANE_02462	0.0	-	-	-	S	ko:K06921	-	ko00000	ATPase domain predominantly from Archaea
HPADDANE_02463	6.54e-19	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HPADDANE_02464	0.0	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HPADDANE_02466	3.58e-38	-	-	-	L	-	-	-	RelB antitoxin
HPADDANE_02467	2.41e-16	-	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	addiction module toxin, RelE StbE family
HPADDANE_02468	6.79e-47	-	-	-	-	-	-	-	-
HPADDANE_02470	2.3e-17	-	-	-	L	-	-	-	DNA integration
HPADDANE_02473	9.96e-76	-	-	-	F	-	-	-	Calcineurin-like phosphoesterase
HPADDANE_02474	4.73e-104	ptxC	-	-	U	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HPADDANE_02475	8.38e-100	-	-	-	U	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HPADDANE_02476	1.7e-104	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HPADDANE_02477	2.87e-145	-	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, phosphonate, periplasmic substrate-binding protein
HPADDANE_02478	1.12e-24	-	-	-	K	-	-	-	Transcriptional regulator, rpir family
HPADDANE_02479	1.03e-33	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HPADDANE_02480	1.51e-257	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
HPADDANE_02481	1.18e-185	-	-	-	S	ko:K07043	-	ko00000	Protein of unknown function DUF45
HPADDANE_02482	0.0	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
HPADDANE_02483	3.14e-109	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
HPADDANE_02484	3.36e-305	-	-	-	P	ko:K03699	-	ko00000,ko02042	Transporter associated domain
HPADDANE_02485	1.23e-256	-	-	-	S	-	-	-	AAA ATPase domain
HPADDANE_02486	1.42e-102	-	-	-	V	ko:K01990,ko:K21397	-	ko00000,ko00002,ko02000	Forkhead associated domain
HPADDANE_02487	1.28e-155	cah	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
HPADDANE_02488	9.71e-138	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	C-terminal domain of 1-Cys peroxiredoxin
HPADDANE_02489	0.0	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Thioredoxin domain
HPADDANE_02490	1.6e-307	-	-	-	EGP	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
HPADDANE_02491	2.11e-160	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
HPADDANE_02492	0.000161	-	-	-	L	-	-	-	Transposase DDE domain
HPADDANE_02493	9.26e-82	-	-	-	L	-	-	-	PFAM Integrase catalytic
HPADDANE_02494	1.12e-91	-	-	-	L	-	-	-	Transposase
HPADDANE_02495	2.56e-238	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HPADDANE_02496	0.0	-	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HPADDANE_02497	4.73e-214	-	-	-	G	ko:K02025,ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HPADDANE_02498	4.43e-193	-	-	-	P	ko:K02026,ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HPADDANE_02499	1.88e-290	-	-	-	M	-	-	-	Protein of unknown function (DUF2961)
HPADDANE_02500	1.51e-159	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HPADDANE_02501	6.5e-30	-	-	-	L	-	-	-	PFAM Integrase catalytic