ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
EPKEEPDC_00001 3.45e-208 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
EPKEEPDC_00002 1.09e-51 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
EPKEEPDC_00003 3.55e-312 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
EPKEEPDC_00004 4.34e-200 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EPKEEPDC_00005 4.8e-86 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EPKEEPDC_00006 1.65e-88 yqhY - - S - - - protein conserved in bacteria
EPKEEPDC_00007 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
EPKEEPDC_00008 3.21e-93 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
EPKEEPDC_00009 9.92e-135 spoIIIAH - - S ko:K06397 - ko00000 SpoIIIAH-like protein
EPKEEPDC_00010 9.25e-150 spoIIIAG - - S ko:K06396 - ko00000 stage III sporulation protein AG
EPKEEPDC_00011 1.28e-131 spoIIIAF - - S ko:K06395 - ko00000 Stage III sporulation protein AF (Spore_III_AF)
EPKEEPDC_00012 7.65e-257 spoIIIAE - - S ko:K06394 - ko00000 stage III sporulation protein AE
EPKEEPDC_00013 1.93e-77 spoIIIAD - - S ko:K06393 - ko00000 Stage III sporulation protein AD
EPKEEPDC_00014 1.63e-39 spoIIIAC - - S ko:K06392 - ko00000 stage III sporulation protein AC
EPKEEPDC_00015 3.29e-110 spoIIIAB - - S ko:K06391 - ko00000 Stage III sporulation protein
EPKEEPDC_00016 8.22e-217 spoIIIAA - - S ko:K06390 - ko00000 stage III sporulation protein AA
EPKEEPDC_00017 6.96e-50 yqhV - - S - - - Protein of unknown function (DUF2619)
EPKEEPDC_00018 4.8e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EPKEEPDC_00019 2.99e-249 yqhT 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
EPKEEPDC_00020 1.94e-100 aroQ 4.2.1.10 - E ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a trans-dehydration via an enolate intermediate
EPKEEPDC_00021 8.02e-121 yqhR - - S - - - Conserved membrane protein YqhR
EPKEEPDC_00022 6.02e-220 yqhQ - - S - - - Protein of unknown function (DUF1385)
EPKEEPDC_00023 5.18e-81 yqhP - - - - - - -
EPKEEPDC_00024 1.21e-210 yqhO - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
EPKEEPDC_00025 1.97e-97 mntR - - K ko:K03709 - ko00000,ko03000 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
EPKEEPDC_00026 3.73e-203 lipM 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
EPKEEPDC_00027 7.5e-83 yqhL - - P - - - COG0607 Rhodanese-related sulfurtransferase
EPKEEPDC_00028 0.0 gcvPB 1.4.4.2 - E ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EPKEEPDC_00029 0.0 gcvPA 1.4.4.2 - E ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EPKEEPDC_00030 3.31e-262 gcvT 2.1.2.10 - E ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
EPKEEPDC_00031 0.0 yqhH - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
EPKEEPDC_00032 1.77e-194 yqhG - - S - - - Bacterial protein YqhG of unknown function
EPKEEPDC_00033 1.39e-33 sinI - - S ko:K06372 - ko00000 Anti-repressor SinI
EPKEEPDC_00034 3.69e-72 sinR - - K ko:K19449 - ko00000,ko03000 transcriptional
EPKEEPDC_00035 3.14e-182 tasA_1 - - S ko:K06336 - ko00000,ko01002 Cell division protein FtsN
EPKEEPDC_00036 7.4e-98 sipW 3.4.21.89 - U ko:K13280 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase
EPKEEPDC_00037 5.16e-152 yqxM - - - ko:K19433 - ko00000 -
EPKEEPDC_00038 4.33e-69 yqzG - - S - - - Protein of unknown function (DUF3889)
EPKEEPDC_00039 4.9e-37 yqzE - - S - - - YqzE-like protein
EPKEEPDC_00040 3.78e-57 - - - S ko:K02249 - ko00000,ko00002,ko02044 ComG operon protein 7
EPKEEPDC_00041 7.11e-47 comGF - - U ko:K02246,ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
EPKEEPDC_00042 2.08e-77 comGE - - - ko:K02247 - ko00000,ko00002,ko02044 -
EPKEEPDC_00043 1.49e-88 gspH - - NU ko:K02246,ko:K02457,ko:K02459,ko:K02672,ko:K08084,ko:K10926 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02035,ko02044 protein transport across the cell outer membrane
EPKEEPDC_00044 5.33e-63 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
EPKEEPDC_00045 1.44e-217 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 COG1459 Type II secretory pathway, component PulF
EPKEEPDC_00046 5.23e-256 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EPKEEPDC_00047 0.000111 - - - S - - - Domain in cystathionine beta-synthase and other proteins.
EPKEEPDC_00048 7.17e-232 yqxL - - P - - - Mg2 transporter protein
EPKEEPDC_00049 2.86e-305 yqhB - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
EPKEEPDC_00050 6.84e-190 yqhA - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
EPKEEPDC_00052 7.79e-85 yqgZ 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
EPKEEPDC_00053 1.46e-50 yqgY - - S - - - Protein of unknown function (DUF2626)
EPKEEPDC_00054 1.52e-155 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
EPKEEPDC_00055 1.91e-31 yqgW - - S - - - Protein of unknown function (DUF2759)
EPKEEPDC_00056 7.65e-66 yqgV - - S - - - Thiamine-binding protein
EPKEEPDC_00057 2.69e-256 yqgU - - - - - - -
EPKEEPDC_00058 1.69e-280 yqgT 3.4.19.11 - E ko:K01308 - ko00000,ko01000,ko01002 Gamma-D-glutamyl-L-diamino acid endopeptidase
EPKEEPDC_00059 0.0 yqgS 2.7.8.20 - M ko:K01138,ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
EPKEEPDC_00060 2.31e-230 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
EPKEEPDC_00061 1.27e-43 yqgQ - - S - - - Protein conserved in bacteria
EPKEEPDC_00062 0.0 gluP 3.4.21.105 - O ko:K19225 - ko00000,ko01000,ko01002 membrane protein (homolog of Drosophila rhomboid)
EPKEEPDC_00063 3.38e-14 yqgO - - - - - - -
EPKEEPDC_00064 3.25e-136 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EPKEEPDC_00065 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
EPKEEPDC_00066 1.74e-251 yqgM 2.4.1.250 - M ko:K15521 - ko00000,ko01000 Glycosyl transferases group 1
EPKEEPDC_00068 2.81e-67 yqzD - - - - - - -
EPKEEPDC_00069 2.92e-98 yqzC - - S - - - YceG-like family
EPKEEPDC_00070 1.57e-186 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
EPKEEPDC_00071 9.78e-190 pstBA 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
EPKEEPDC_00072 3.55e-200 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
EPKEEPDC_00073 7.11e-203 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
EPKEEPDC_00074 6.14e-204 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
EPKEEPDC_00075 0.0 pbpA - - M ko:K21465,ko:K21466 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
EPKEEPDC_00076 3.96e-293 yqgE - - EGP ko:K08222 - ko00000,ko02000 Major facilitator superfamily
EPKEEPDC_00077 1.59e-148 sodA 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
EPKEEPDC_00078 8.25e-101 yqgC - - S ko:K09793 - ko00000 protein conserved in bacteria
EPKEEPDC_00079 7.62e-171 yqgB - - S - - - Protein of unknown function (DUF1189)
EPKEEPDC_00080 8.33e-99 yqgA - - - - - - -
EPKEEPDC_00081 1.35e-61 yqfZ - - M ko:K06417 - ko00000 LysM domain
EPKEEPDC_00082 5.22e-257 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EPKEEPDC_00083 2.04e-81 yqfX - - S - - - membrane
EPKEEPDC_00084 1.37e-140 yqfW - - S ko:K05967 - ko00000 Belongs to the 5'(3')-deoxyribonucleotidase family
EPKEEPDC_00085 4.98e-106 zur - - P ko:K02076 - ko00000,ko03000 Belongs to the Fur family
EPKEEPDC_00086 3.83e-199 yqfU - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
EPKEEPDC_00087 3.01e-49 yqfT - - S - - - Protein of unknown function (DUF2624)
EPKEEPDC_00088 1.04e-214 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EPKEEPDC_00089 1.09e-310 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
EPKEEPDC_00090 1.14e-53 yqfQ - - S - - - YqfQ-like protein
EPKEEPDC_00091 1.75e-226 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EPKEEPDC_00092 1.08e-268 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EPKEEPDC_00093 1.63e-148 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
EPKEEPDC_00094 1.61e-81 cccA - - C ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
EPKEEPDC_00095 2.79e-254 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
EPKEEPDC_00096 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
EPKEEPDC_00097 6.03e-114 yqxD - - S ko:K09768 - ko00000 Belongs to the UPF0178 family
EPKEEPDC_00098 6.38e-191 yqfL 2.7.11.33, 2.7.4.28 - S ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
EPKEEPDC_00099 3.29e-144 ccpN - - K - - - CBS domain
EPKEEPDC_00100 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
EPKEEPDC_00101 2.12e-222 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
EPKEEPDC_00102 7.48e-187 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
EPKEEPDC_00103 5.29e-27 - - - S - - - YqzL-like protein
EPKEEPDC_00104 9.98e-215 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EPKEEPDC_00105 6.71e-93 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
EPKEEPDC_00106 4.75e-80 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
EPKEEPDC_00107 8.68e-106 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EPKEEPDC_00108 0.0 yqfF - - S ko:K07037 - ko00000 membrane-associated HD superfamily hydrolase
EPKEEPDC_00110 4.99e-224 phoH - - T ko:K06217 - ko00000 Phosphate starvation-inducible protein PhoH
EPKEEPDC_00111 1.04e-242 yqfD - - S ko:K06438 - ko00000 Stage IV sporulation
EPKEEPDC_00112 2.07e-60 yqfC - - S - - - sporulation protein YqfC
EPKEEPDC_00113 5.2e-78 yqfB - - - - - - -
EPKEEPDC_00114 4.35e-192 yqfA - - S - - - UPF0365 protein
EPKEEPDC_00115 5.51e-231 yqeZ - - O ko:K07403 - ko00000 COG1030 Membrane-bound serine protease (ClpP class)
EPKEEPDC_00116 7.61e-38 yqeZ - - O ko:K07403 - ko00000 COG1030 Membrane-bound serine protease (ClpP class)
EPKEEPDC_00117 2.25e-90 yqeY - - S ko:K09117 - ko00000 Yqey-like protein
EPKEEPDC_00118 1.03e-26 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
EPKEEPDC_00119 3.26e-201 yqeW - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
EPKEEPDC_00120 0.0 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 ribosomal protein S12 methylthiotransferase
EPKEEPDC_00121 3.96e-178 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
EPKEEPDC_00122 2.2e-223 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
EPKEEPDC_00123 3.41e-257 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
EPKEEPDC_00124 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
EPKEEPDC_00125 4.36e-116 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EPKEEPDC_00126 1.65e-241 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
EPKEEPDC_00127 2.9e-276 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
EPKEEPDC_00128 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
EPKEEPDC_00129 1.43e-69 yqxA - - S - - - Protein of unknown function (DUF3679)
EPKEEPDC_00130 2.73e-283 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
EPKEEPDC_00131 1.39e-257 gpr 3.4.24.78 - C ko:K06012 - ko00000,ko01000,ko01002 Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EPKEEPDC_00132 4e-49 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
EPKEEPDC_00133 2.35e-243 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
EPKEEPDC_00134 2.36e-22 - - - S - - - YqzM-like protein
EPKEEPDC_00135 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
EPKEEPDC_00136 2.67e-136 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
EPKEEPDC_00137 1.5e-134 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
EPKEEPDC_00138 1.1e-188 comER - - E ko:K02239 - ko00000,ko00002,ko02044 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EPKEEPDC_00139 6.62e-177 yqeM - - Q - - - Methyltransferase
EPKEEPDC_00140 1.39e-81 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
EPKEEPDC_00141 3.95e-132 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
EPKEEPDC_00142 4.99e-141 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EPKEEPDC_00143 8.95e-61 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein containing KH domain, possibly ribosomal protein
EPKEEPDC_00144 8.1e-199 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EPKEEPDC_00145 9.65e-273 yqeH - - S ko:K06948 - ko00000,ko03009 In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
EPKEEPDC_00146 2.17e-123 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
EPKEEPDC_00148 3.71e-181 yqeF - - E - - - GDSL-like Lipase/Acylhydrolase
EPKEEPDC_00149 5.03e-178 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
EPKEEPDC_00150 3.81e-134 yqeD - - S - - - SNARE associated Golgi protein
EPKEEPDC_00151 2.45e-213 yqeC 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconate dehydrogenase
EPKEEPDC_00152 1.49e-167 - - - - - - - -
EPKEEPDC_00153 2.53e-97 nucB - - M - - - Deoxyribonuclease NucA/NucB
EPKEEPDC_00154 1.1e-72 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EPKEEPDC_00155 0.0 - - - L ko:K06400 - ko00000 Recombinase
EPKEEPDC_00157 7.33e-81 - - - - - - - -
EPKEEPDC_00158 6e-77 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
EPKEEPDC_00159 0.000119 pyrE_1 - - S - - - phosphoribosyltransferase
EPKEEPDC_00160 7.66e-07 nt5e 3.1.3.18 - F ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score
EPKEEPDC_00161 7.02e-119 - - - S - - - Tetratricopeptide repeat
EPKEEPDC_00164 0.0 - - - A ko:K21491 - ko00000,ko01000,ko02048 Pre-toxin TG
EPKEEPDC_00165 3.77e-133 - - - S ko:K21492 - ko00000,ko02048 Suppressor of fused protein (SUFU)
EPKEEPDC_00166 8.84e-68 - - - S - - - Immunity protein 50
EPKEEPDC_00168 2.19e-90 yokH - - G - - - SMI1 / KNR4 family
EPKEEPDC_00169 9.58e-71 - - - V - - - HNH endonuclease
EPKEEPDC_00170 1.62e-169 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
EPKEEPDC_00171 6.87e-88 - - - S - - - Bacteriophage holin family
EPKEEPDC_00172 1.4e-203 xepA - - - - - - -
EPKEEPDC_00173 1.45e-27 - - - - - - - -
EPKEEPDC_00174 7.41e-57 xkdW - - S - - - XkdW protein
EPKEEPDC_00175 2.24e-207 - - - - - - - -
EPKEEPDC_00176 7.09e-53 - - - - - - - -
EPKEEPDC_00177 2.74e-126 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
EPKEEPDC_00178 9.48e-239 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
EPKEEPDC_00179 3.14e-89 xkdS - - S - - - Protein of unknown function (DUF2634)
EPKEEPDC_00180 2.34e-50 xkdR - - S - - - Protein of unknown function (DUF2577)
EPKEEPDC_00181 7.68e-227 xkdQ - - G - - - NLP P60 protein
EPKEEPDC_00182 1.5e-150 xkdP - - S - - - Lysin motif
EPKEEPDC_00183 0.0 xkdO - - L - - - Transglycosylase SLT domain
EPKEEPDC_00184 8.84e-89 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
EPKEEPDC_00186 4.23e-99 xkdM - - S - - - Phage tail tube protein
EPKEEPDC_00187 0.0 xkdK - - S - - - Phage tail sheath C-terminal domain
EPKEEPDC_00188 8.49e-35 - - - - - - - -
EPKEEPDC_00189 4.26e-98 yqbJ - - - - - - -
EPKEEPDC_00190 6.48e-115 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
EPKEEPDC_00191 4.44e-79 yqbH - - S - - - Domain of unknown function (DUF3599)
EPKEEPDC_00192 4.1e-87 - - - S - - - Protein of unknown function (DUF3199)
EPKEEPDC_00193 6.56e-64 - - - S - - - YqbF, hypothetical protein domain
EPKEEPDC_00194 7.57e-215 xkdG - - S - - - Phage capsid family
EPKEEPDC_00195 2.84e-163 yqbD - - L - - - Putative phage serine protease XkdF
EPKEEPDC_00197 6.36e-188 - - - S - - - Phage Mu protein F like protein
EPKEEPDC_00198 0.0 yqbA - - S - - - portal protein
EPKEEPDC_00199 1.62e-313 yqaT - - S ko:K06909 - ko00000 phage terminase, large subunit
EPKEEPDC_00200 1.06e-111 yqaS - - L - - - DNA packaging
EPKEEPDC_00201 5.57e-86 - - - S - - - Region found in RelA / SpoT proteins
EPKEEPDC_00205 4.59e-10 - - - - - - - -
EPKEEPDC_00206 5.72e-99 yqaQ - - L - - - Transposase
EPKEEPDC_00207 5.99e-52 - - - D - - - nuclear chromosome segregation
EPKEEPDC_00208 5.65e-42 yqaO - - S - - - Phage-like element PBSX protein XtrA
EPKEEPDC_00209 1.28e-93 rusA - - L - - - Endodeoxyribonuclease RusA
EPKEEPDC_00211 6.38e-180 yqaM - - L - - - IstB-like ATP binding protein
EPKEEPDC_00212 5.07e-154 yqaL - - L - - - DnaD domain protein
EPKEEPDC_00213 6.85e-193 recT - - L ko:K07455 - ko00000,ko03400 RecT family
EPKEEPDC_00214 2.03e-223 yqaJ - - L - - - YqaJ-like viral recombinase domain
EPKEEPDC_00218 1.04e-133 - - - - - - - -
EPKEEPDC_00220 1.57e-47 - - - K - - - Helix-turn-helix XRE-family like proteins
EPKEEPDC_00221 1.25e-74 - - - K - - - sequence-specific DNA binding
EPKEEPDC_00222 2.93e-11 - - - S - - - Protein of unknown function (DUF4064)
EPKEEPDC_00223 4.53e-122 xkdA - - E - - - IrrE N-terminal-like domain
EPKEEPDC_00224 4.46e-79 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EPKEEPDC_00225 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
EPKEEPDC_00226 1.14e-197 yybE - - K - - - Transcriptional regulator
EPKEEPDC_00227 2.12e-197 ydhE - - CG - - - UDP-glucoronosyl and UDP-glucosyl transferase
EPKEEPDC_00228 2.15e-90 psiE - - S ko:K13256 - ko00000 Protein PsiE homolog
EPKEEPDC_00229 2.45e-304 yrkQ - - T - - - Histidine kinase
EPKEEPDC_00230 8.35e-163 yrkP - - T ko:K02483 - ko00000,ko02022 Transcriptional regulator
EPKEEPDC_00231 3.06e-282 yrkO - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
EPKEEPDC_00232 5.41e-134 yrkN - - K - - - Acetyltransferase (GNAT) family
EPKEEPDC_00233 5.71e-126 yrkL - - S ko:K11748 - ko00000,ko02000 Flavodoxin-like fold
EPKEEPDC_00234 9.36e-104 - - - S - - - Protein of unknown function with HXXEE motif
EPKEEPDC_00235 6.63e-162 yrkJ - - S ko:K07090 - ko00000 membrane transporter protein
EPKEEPDC_00236 6.46e-49 yrkI - - O - - - Belongs to the sulfur carrier protein TusA family
EPKEEPDC_00237 8.57e-272 yrkH - - P - - - Rhodanese Homology Domain
EPKEEPDC_00238 5.84e-129 yrkF - - OP - - - Belongs to the sulfur carrier protein TusA family
EPKEEPDC_00239 1.88e-106 yrkE - - O - - - DsrE/DsrF/DrsH-like family
EPKEEPDC_00240 4.38e-52 yrkD - - S - - - protein conserved in bacteria
EPKEEPDC_00241 1.9e-27 - - - - - - - -
EPKEEPDC_00242 1.28e-137 yrkC - - G - - - Cupin domain
EPKEEPDC_00243 1.24e-194 bltR - - K - - - helix_turn_helix, mercury resistance
EPKEEPDC_00244 2.17e-268 blt - - EGP ko:K08153,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
EPKEEPDC_00245 2.16e-108 bltD 2.3.1.57 - K ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 FR47-like protein
EPKEEPDC_00246 3.27e-294 yrkA - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
EPKEEPDC_00247 7.04e-23 - - - S - - - YrzO-like protein
EPKEEPDC_00248 4.91e-216 yrdR - - EG - - - EamA-like transporter family
EPKEEPDC_00249 1.64e-202 - - - K - - - Transcriptional regulator
EPKEEPDC_00250 1.01e-252 trkA - - P ko:K07222 - ko00000 Oxidoreductase
EPKEEPDC_00251 2.64e-215 czcD - - P ko:K16264 - ko00000,ko02000 COG1230 Co Zn Cd efflux system component
EPKEEPDC_00252 7.09e-292 brnQ - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
EPKEEPDC_00253 1.97e-66 azlD - - E - - - Branched-chain amino acid transport protein (AzlD)
EPKEEPDC_00254 6.57e-176 azlC - - E - - - AzlC protein
EPKEEPDC_00255 4.82e-103 bkdR - - K - - - helix_turn_helix ASNC type
EPKEEPDC_00256 2.19e-289 cypA 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
EPKEEPDC_00257 2.11e-130 yrdC - - Q - - - Isochorismatase family
EPKEEPDC_00258 1.04e-71 - - - S - - - Protein of unknown function (DUF2568)
EPKEEPDC_00259 2.06e-11 M1-394 - - S - - - Domain of unknown function (DUF4280)
EPKEEPDC_00260 2.14e-53 - - - - - - - -
EPKEEPDC_00261 8.53e-120 yrdA - - S - - - DinB family
EPKEEPDC_00262 8.54e-212 aadK - - G ko:K05593 - ko00000,ko01000,ko01504 Streptomycin adenylyltransferase
EPKEEPDC_00263 5.15e-247 npd 1.13.12.16 - S ko:K00459 ko00910,map00910 ko00000,ko00001,ko01000 COG2070 Dioxygenases related to 2-nitropropane dioxygenase
EPKEEPDC_00264 3.98e-187 murI 5.1.1.3 - M ko:K01776 ko00471,ko01100,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
EPKEEPDC_00265 2.39e-162 yrpD - - S - - - Domain of unknown function, YrpD
EPKEEPDC_00266 8.53e-166 zinT - - S ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
EPKEEPDC_00267 3.7e-123 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
EPKEEPDC_00268 4.9e-239 yrpG - - C - - - Aldo/keto reductase family
EPKEEPDC_00269 5.91e-283 yraO - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
EPKEEPDC_00270 2.97e-210 yraN - - K - - - Transcriptional regulator
EPKEEPDC_00271 3.85e-259 yraM - - S - - - PrpF protein
EPKEEPDC_00272 2.57e-192 csn 3.2.1.132 - M ko:K01233 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
EPKEEPDC_00273 5.07e-56 yraL - - S - - - COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EPKEEPDC_00274 1.02e-192 - - - S - - - Alpha beta hydrolase
EPKEEPDC_00275 1.33e-79 - - - T - - - sh3 domain protein
EPKEEPDC_00276 2.92e-81 - - - T - - - sh3 domain protein
EPKEEPDC_00277 5.06e-87 - - - E - - - Glyoxalase-like domain
EPKEEPDC_00278 4.19e-50 yraG - - - ko:K06440 - ko00000 -
EPKEEPDC_00279 9.61e-84 yraF - - M - - - Spore coat protein
EPKEEPDC_00280 3.41e-279 adhB 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
EPKEEPDC_00281 1.23e-35 yraE - - - ko:K06440 - ko00000 -
EPKEEPDC_00282 7.23e-66 yraD - - M ko:K06439 - ko00000 Spore coat protein
EPKEEPDC_00283 3.17e-68 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
EPKEEPDC_00284 4.53e-33 yphJ 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 peroxiredoxin activity
EPKEEPDC_00285 2.78e-252 adhA - - C ko:K13979 - ko00000,ko01000 alcohol dehydrogenase
EPKEEPDC_00286 1.58e-116 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
EPKEEPDC_00287 0.0 sacC 3.2.1.80 - G ko:K03332 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
EPKEEPDC_00288 1.39e-192 levG - - G ko:K02771,ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
EPKEEPDC_00289 6.11e-168 levF - - G ko:K02746,ko:K02795,ko:K11196 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
EPKEEPDC_00290 7.63e-107 ptnA 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11195 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system mannose fructose sorbose family
EPKEEPDC_00291 2.66e-97 levD 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11194 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
EPKEEPDC_00292 0.0 levR - - K - - - PTS system fructose IIA component
EPKEEPDC_00293 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
EPKEEPDC_00294 5.63e-137 yrhP - - E - - - LysE type translocator
EPKEEPDC_00295 5.66e-192 yrhO - - K - - - Archaeal transcriptional regulator TrmB
EPKEEPDC_00296 9.97e-114 sigV - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
EPKEEPDC_00297 1.01e-190 rsiV - - S - - - Protein of unknown function (DUF3298)
EPKEEPDC_00298 0.0 oatA - - I - - - Acyltransferase family
EPKEEPDC_00299 6.32e-59 yrhK - - S - - - YrhK-like protein
EPKEEPDC_00300 0.0 yrhJ 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
EPKEEPDC_00301 2.26e-135 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
EPKEEPDC_00302 1.05e-124 yrhH - - Q - - - methyltransferase
EPKEEPDC_00303 9.39e-08 - - - S - - - Probable sporulation protein (Bac_small_yrzI)
EPKEEPDC_00305 1.38e-183 yrhG - - P ko:K21993 - ko00000,ko02000 Formate nitrite
EPKEEPDC_00306 4.41e-80 yrhF - - S - - - Uncharacterized conserved protein (DUF2294)
EPKEEPDC_00307 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
EPKEEPDC_00308 6.05e-103 yrhD - - S - - - Protein of unknown function (DUF1641)
EPKEEPDC_00309 6.93e-49 yrhC - - S - - - YrhC-like protein
EPKEEPDC_00310 4.95e-268 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
EPKEEPDC_00311 1.36e-215 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Cysteine synthase
EPKEEPDC_00312 5.64e-161 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EPKEEPDC_00313 3.44e-153 yrrT - - Q ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Could be a S-adenosyl-L-methionine-dependent methyltransferase
EPKEEPDC_00314 4.94e-36 yrzA - - S - - - Protein of unknown function (DUF2536)
EPKEEPDC_00315 8.2e-102 yrrS - - S - - - Protein of unknown function (DUF1510)
EPKEEPDC_00316 0.0 pbpI - - M ko:K21468 - ko00000,ko01011 Penicillin-binding Protein
EPKEEPDC_00317 1.14e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
EPKEEPDC_00318 4.51e-148 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
EPKEEPDC_00319 4.62e-313 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 COG0826 Collagenase and related proteases
EPKEEPDC_00320 1.09e-222 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
EPKEEPDC_00321 6.92e-155 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-methyltransferase
EPKEEPDC_00322 2.15e-241 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EPKEEPDC_00323 2.94e-60 yrzB - - S - - - Belongs to the UPF0473 family
EPKEEPDC_00324 5.49e-93 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EPKEEPDC_00325 2.22e-55 yrzL - - S - - - Belongs to the UPF0297 family
EPKEEPDC_00326 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EPKEEPDC_00327 3.07e-242 yrrI - - S - - - AI-2E family transporter
EPKEEPDC_00328 1.28e-167 glnQ - - E ko:K09972,ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
EPKEEPDC_00329 1.01e-184 glnH - - ET ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
EPKEEPDC_00330 3.24e-139 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
EPKEEPDC_00331 2.18e-138 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
EPKEEPDC_00332 5.38e-12 - - - S - - - Protein of unknown function (DUF3918)
EPKEEPDC_00333 8.4e-42 yrzR - - - - - - -
EPKEEPDC_00334 1.44e-107 yrrD - - S - - - protein conserved in bacteria
EPKEEPDC_00335 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
EPKEEPDC_00336 1.01e-20 yrrB - - S - - - COG0457 FOG TPR repeat
EPKEEPDC_00337 1.62e-278 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
EPKEEPDC_00338 3.63e-270 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
EPKEEPDC_00339 8.12e-93 cymR - - K ko:K17472 - ko00000,ko03000 Transcriptional regulator
EPKEEPDC_00340 6.98e-303 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
EPKEEPDC_00341 2.29e-176 yrvM - - H ko:K22132 - ko00000,ko03016 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
EPKEEPDC_00342 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EPKEEPDC_00343 3e-310 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
EPKEEPDC_00345 0.0 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG3103 SH3 domain protein
EPKEEPDC_00346 1.36e-90 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
EPKEEPDC_00347 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EPKEEPDC_00348 2.53e-118 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EPKEEPDC_00349 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
EPKEEPDC_00350 1.07e-64 yrvD - - S - - - Lipopolysaccharide assembly protein A domain
EPKEEPDC_00351 4.94e-109 trkA1 - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
EPKEEPDC_00352 0.0 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EPKEEPDC_00353 5.53e-65 yrzD - - S - - - Post-transcriptional regulator
EPKEEPDC_00354 0.0 spoVB - - S ko:K06409 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EPKEEPDC_00355 5.83e-143 yrbG - - S - - - membrane
EPKEEPDC_00356 1.46e-96 yrzE - - S - - - Protein of unknown function (DUF3792)
EPKEEPDC_00357 1.29e-52 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit YajC
EPKEEPDC_00358 2.74e-291 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
EPKEEPDC_00359 7.04e-247 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EPKEEPDC_00360 2.91e-30 yrzS - - S - - - Protein of unknown function (DUF2905)
EPKEEPDC_00361 9.14e-239 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
EPKEEPDC_00362 2.84e-137 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
EPKEEPDC_00363 6.46e-121 bofC - - S ko:K06318 - ko00000 BofC C-terminal domain
EPKEEPDC_00364 0.0 csbX - - EGP - - - the major facilitator superfamily
EPKEEPDC_00365 3.61e-115 idhA 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, NAD-binding Rossmann fold
EPKEEPDC_00366 4.42e-109 idhA 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, NAD-binding Rossmann fold
EPKEEPDC_00367 1.91e-151 yrzF - - T - - - serine threonine protein kinase
EPKEEPDC_00369 4.45e-68 - - - S - - - Family of unknown function (DUF5412)
EPKEEPDC_00370 0.0 yrbD - - E ko:K03310 - ko00000 Sodium alanine symporter
EPKEEPDC_00371 8.63e-165 yebC - - K - - - transcriptional regulatory protein
EPKEEPDC_00372 2.55e-70 - - - S ko:K06345 - ko00000 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
EPKEEPDC_00373 5.7e-216 safA - - M ko:K06370 - ko00000 spore coat assembly protein SafA
EPKEEPDC_00374 1.04e-268 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EPKEEPDC_00375 2.41e-200 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
EPKEEPDC_00376 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
EPKEEPDC_00377 1.17e-290 nifS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
EPKEEPDC_00378 1.01e-122 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
EPKEEPDC_00379 1.43e-208 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
EPKEEPDC_00380 4.75e-96 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
EPKEEPDC_00381 1.6e-307 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EPKEEPDC_00382 4.25e-139 spo0B - - T ko:K06375 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Sporulation initiation phospho-transferase B, C-terminal
EPKEEPDC_00383 2.7e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
EPKEEPDC_00384 2.66e-74 ysxB - - J ko:K07584 - ko00000 ribosomal protein
EPKEEPDC_00385 6.34e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
EPKEEPDC_00386 3.74e-208 spoIVFB - - S ko:K06402 - ko00000,ko01000,ko01002 Stage IV sporulation protein
EPKEEPDC_00387 5.24e-187 spoIVFA - - M ko:K06401 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
EPKEEPDC_00388 6.84e-185 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
EPKEEPDC_00389 4.3e-158 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
EPKEEPDC_00390 8.72e-111 mreD - - M ko:K03571 - ko00000,ko03036 shape-determining protein
EPKEEPDC_00391 7.78e-202 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
EPKEEPDC_00392 5.26e-235 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein MreB
EPKEEPDC_00393 8.35e-163 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
EPKEEPDC_00394 7.06e-132 maf - - D ko:K06287 - ko00000 septum formation protein Maf
EPKEEPDC_00395 1.23e-210 spoIIB - - S ko:K06380 - ko00000 Sporulation related domain
EPKEEPDC_00396 3.08e-162 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
EPKEEPDC_00397 1.55e-315 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
EPKEEPDC_00398 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
EPKEEPDC_00399 1.53e-35 - - - - - - - -
EPKEEPDC_00400 1.96e-251 ysxE - - S - - - A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EPKEEPDC_00401 0.0 spoVID - - M ko:K06417 - ko00000 stage VI sporulation protein D
EPKEEPDC_00402 3.53e-312 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
EPKEEPDC_00403 2.14e-232 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the ALAD family
EPKEEPDC_00404 1.01e-183 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
EPKEEPDC_00405 5.15e-219 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
EPKEEPDC_00406 6.56e-187 hemX - - O ko:K02497 - ko00000 cytochrome C
EPKEEPDC_00407 2.74e-315 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EPKEEPDC_00408 4.77e-116 ysxD - - - - - - -
EPKEEPDC_00409 7.6e-139 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
EPKEEPDC_00410 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EPKEEPDC_00411 0.0 lonB 3.4.21.53 - LO ko:K04076 - ko00000,ko01000,ko01002 Belongs to the peptidase S16 family
EPKEEPDC_00412 1.15e-296 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EPKEEPDC_00413 8.87e-287 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
EPKEEPDC_00414 1.25e-236 ysoA - - H - - - Tetratricopeptide repeat
EPKEEPDC_00415 4.4e-149 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EPKEEPDC_00416 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EPKEEPDC_00417 3.53e-254 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
EPKEEPDC_00418 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EPKEEPDC_00419 5.55e-244 ilvC 1.1.1.86 - EH ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EPKEEPDC_00420 5.05e-110 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
EPKEEPDC_00421 0.0 ilvB 2.2.1.6 - E ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
EPKEEPDC_00423 2.83e-99 ysnE - - K ko:K03829 - ko00000,ko01000 acetyltransferase
EPKEEPDC_00424 1.11e-203 - - - N - - - domain, Protein
EPKEEPDC_00425 3.36e-181 ysnF - - S - - - protein conserved in bacteria
EPKEEPDC_00427 4.05e-119 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
EPKEEPDC_00428 7.86e-132 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EPKEEPDC_00429 2.04e-170 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EPKEEPDC_00430 5.65e-256 gerM - - S ko:K06298 - ko00000 COG5401 Spore germination protein
EPKEEPDC_00431 4.49e-194 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
EPKEEPDC_00432 1.6e-98 ysmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
EPKEEPDC_00433 1.81e-41 gerE - - K ko:K01994 - ko00000,ko03000 Transcriptional regulator
EPKEEPDC_00434 3.1e-101 ysmA - - S ko:K07107 - ko00000,ko01000 thioesterase
EPKEEPDC_00435 1.15e-189 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
EPKEEPDC_00436 0.0 sdhA 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
EPKEEPDC_00437 1.35e-140 sdhC - - C ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 succinate dehydrogenase
EPKEEPDC_00438 8.53e-104 yslB - - S - - - Protein of unknown function (DUF2507)
EPKEEPDC_00439 4.83e-276 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
EPKEEPDC_00440 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
EPKEEPDC_00441 1.12e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
EPKEEPDC_00442 0.0 xsa 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
EPKEEPDC_00444 2.89e-226 etfA - - C ko:K03522 - ko00000,ko04147 Electron transfer flavoprotein
EPKEEPDC_00445 2.58e-179 etfB - - C ko:K03521 - ko00000 Electron transfer flavoprotein
EPKEEPDC_00446 6.3e-176 fadB 4.2.1.17 - I ko:K13767 ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the enoyl-CoA hydratase isomerase family
EPKEEPDC_00447 5.74e-129 fadR - - K ko:K13770 - ko00000,ko03000 Transcriptional regulator
EPKEEPDC_00448 0.0 lcfA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
EPKEEPDC_00449 3.76e-89 yshE - - S ko:K08989 - ko00000 membrane
EPKEEPDC_00450 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
EPKEEPDC_00451 0.0 polX - - L ko:K02347 - ko00000,ko03400 COG1796 DNA polymerase IV (family X)
EPKEEPDC_00452 1.09e-111 yshB - - S - - - membrane protein, required for colicin V production
EPKEEPDC_00453 1.04e-54 zapA - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EPKEEPDC_00454 8.48e-215 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EPKEEPDC_00455 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
EPKEEPDC_00456 1.81e-250 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EPKEEPDC_00457 3.13e-171 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EPKEEPDC_00458 4.37e-43 sspI - - S ko:K06426 - ko00000 Belongs to the SspI family
EPKEEPDC_00459 1.45e-259 cdaR_1 - - KT ko:K02647 - ko00000,ko03000 regulator
EPKEEPDC_00460 0.0 glcD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Glycolate oxidase subunit
EPKEEPDC_00461 0.0 glcF - - C ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 Glycolate oxidase
EPKEEPDC_00462 1.26e-69 - 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase-like domain
EPKEEPDC_00463 0.0 cstA - - T ko:K06200 - ko00000 Carbon starvation protein
EPKEEPDC_00464 0.0 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 alpha-L-arabinofuranosidase activity
EPKEEPDC_00465 4.28e-190 araQ - - G ko:K17236 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport system permease
EPKEEPDC_00466 1.94e-218 araP - - G ko:K17235 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
EPKEEPDC_00467 0.0 araN - - G ko:K17234 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
EPKEEPDC_00468 2.24e-283 araM 1.1.1.261 - I ko:K00096 ko00564,map00564 ko00000,ko00001,ko01000 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
EPKEEPDC_00469 4.98e-186 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
EPKEEPDC_00470 1.7e-170 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
EPKEEPDC_00471 0.0 araB 2.7.1.16 - C ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Belongs to the ribulokinase family
EPKEEPDC_00472 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
EPKEEPDC_00473 5.74e-241 - 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
EPKEEPDC_00474 4.35e-262 ysdC - - G - - - COG1363 Cellulase M and related proteins
EPKEEPDC_00475 2.29e-88 ysdB - - S - - - Sigma-w pathway protein YsdB
EPKEEPDC_00476 1.27e-59 ysdA - - S - - - Membrane
EPKEEPDC_00477 3.26e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EPKEEPDC_00478 3.93e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
EPKEEPDC_00479 1.81e-111 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EPKEEPDC_00481 5.34e-150 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
EPKEEPDC_00482 4.9e-84 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
EPKEEPDC_00483 1.96e-166 lytT - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
EPKEEPDC_00484 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EPKEEPDC_00485 1.98e-189 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
EPKEEPDC_00486 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EPKEEPDC_00488 3.46e-205 ytxC - - S - - - YtxC-like family
EPKEEPDC_00489 1.33e-141 ytxB - - S - - - SNARE associated Golgi protein
EPKEEPDC_00490 1.22e-220 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
EPKEEPDC_00491 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 Membrane attachment protein
EPKEEPDC_00492 2.42e-105 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EPKEEPDC_00493 2.42e-88 speH 4.1.1.50 - E ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EPKEEPDC_00494 1.22e-246 gapB 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
EPKEEPDC_00495 9.85e-88 ytcD - - K - - - Transcriptional regulator
EPKEEPDC_00496 4.78e-256 ytbD - - EGP ko:K19577 - ko00000,ko02000 -transporter
EPKEEPDC_00497 4.54e-205 ytbE - - S - - - reductase
EPKEEPDC_00498 2.82e-126 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EPKEEPDC_00499 1.68e-138 ytaF - - P - - - Probably functions as a manganese efflux pump
EPKEEPDC_00500 2.34e-201 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
EPKEEPDC_00501 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EPKEEPDC_00502 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
EPKEEPDC_00503 1.62e-169 phoP - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EPKEEPDC_00504 1.04e-217 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible oxidation of malate to oxaloacetate
EPKEEPDC_00505 9.27e-309 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 isocitrate
EPKEEPDC_00506 1.17e-267 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
EPKEEPDC_00507 9.38e-95 ytwI - - S - - - membrane
EPKEEPDC_00508 2.73e-245 ytvI - - S - - - sporulation integral membrane protein YtvI
EPKEEPDC_00509 3.16e-80 fxsA - - S ko:K07113 - ko00000 COG3030 Protein affecting phage T7 exclusion by the F plasmid
EPKEEPDC_00510 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
EPKEEPDC_00511 4.65e-229 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
EPKEEPDC_00512 9.82e-234 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
EPKEEPDC_00513 1.46e-206 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EPKEEPDC_00514 8.53e-287 ytsJ 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
EPKEEPDC_00515 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
EPKEEPDC_00516 2.45e-75 ytrH - - S - - - Sporulation protein YtrH
EPKEEPDC_00517 5.12e-112 ytrI - - - - - - -
EPKEEPDC_00518 1.15e-39 - - - - - - - -
EPKEEPDC_00519 3.55e-230 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 COG0618 Exopolyphosphatase-related proteins
EPKEEPDC_00520 2.15e-63 ytpI - - S - - - YtpI-like protein
EPKEEPDC_00521 1.13e-308 ytoI - - K - - - transcriptional regulator containing CBS domains
EPKEEPDC_00522 1.45e-202 ytnM - - S ko:K07090 - ko00000 membrane transporter protein
EPKEEPDC_00523 1.72e-305 hipO2 - - E ko:K01436,ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
EPKEEPDC_00524 4.66e-164 - 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin kinase
EPKEEPDC_00525 0.0 ytnJ - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EPKEEPDC_00526 1.51e-62 ytnI - - O - - - COG0695 Glutaredoxin and related proteins
EPKEEPDC_00527 7.2e-236 ytmO - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EPKEEPDC_00528 6.61e-183 tcyN - - E ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
EPKEEPDC_00529 4.76e-155 - - - U ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
EPKEEPDC_00530 1.66e-157 ytmL - - P ko:K16958,ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
EPKEEPDC_00531 3.84e-192 tcyK - - M ko:K16957 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
EPKEEPDC_00532 1.02e-191 - - - ET ko:K16956,ko:K16957,ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
EPKEEPDC_00533 2.81e-128 ytmI - - K ko:K00680 - ko00000,ko01000 Acetyltransferase (GNAT) domain
EPKEEPDC_00534 9.66e-221 ytlI - - K ko:K21960 - ko00000,ko03000 LysR substrate binding domain
EPKEEPDC_00535 3.19e-166 ytkL - - S - - - Belongs to the UPF0173 family
EPKEEPDC_00536 2.81e-182 ytkK 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EPKEEPDC_00538 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
EPKEEPDC_00539 1.06e-297 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
EPKEEPDC_00540 9.5e-114 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
EPKEEPDC_00541 4.69e-281 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EPKEEPDC_00542 3.78e-224 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
EPKEEPDC_00543 1.93e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EPKEEPDC_00544 1.06e-94 ytfJ - - S - - - Sporulation protein YtfJ
EPKEEPDC_00545 2.79e-147 ytfI - - S - - - Protein of unknown function (DUF2953)
EPKEEPDC_00546 2.36e-111 yteJ - - S - - - RDD family
EPKEEPDC_00547 8.34e-231 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA
EPKEEPDC_00548 1.39e-188 nadK2 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EPKEEPDC_00549 0.0 ytcJ - - S - - - amidohydrolase
EPKEEPDC_00550 0.0 ytcI 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
EPKEEPDC_00551 2.12e-40 - - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
EPKEEPDC_00552 6.26e-289 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EPKEEPDC_00553 1.59e-265 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
EPKEEPDC_00554 1.17e-304 braB - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
EPKEEPDC_00555 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EPKEEPDC_00556 5.29e-198 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 COG1387 Histidinol phosphatase and related hydrolases of the PHP family
EPKEEPDC_00557 2.94e-142 yttP - - K - - - Transcriptional regulator
EPKEEPDC_00558 1.95e-114 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
EPKEEPDC_00559 0.0 ytrP - - T - - - COG2199 FOG GGDEF domain
EPKEEPDC_00560 2.01e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EPKEEPDC_00562 5.31e-303 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EPKEEPDC_00563 0.0 acsA 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
EPKEEPDC_00564 2.84e-155 acuA - - K ko:K04766 - ko00000,ko01000 Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
EPKEEPDC_00565 6.16e-152 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
EPKEEPDC_00566 1.49e-289 acuC - - BQ ko:K04768 - ko00000 histone deacetylase
EPKEEPDC_00567 1.6e-161 ytxE - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
EPKEEPDC_00568 6.84e-187 motP - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
EPKEEPDC_00569 4.16e-235 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
EPKEEPDC_00570 7.64e-250 aroA 2.5.1.54, 5.4.99.5 - E ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
EPKEEPDC_00571 1.51e-69 ytxJ - - O - - - Protein of unknown function (DUF2847)
EPKEEPDC_00572 3.17e-30 ytxH - - S - - - COG4980 Gas vesicle protein
EPKEEPDC_00573 1.67e-63 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
EPKEEPDC_00574 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
EPKEEPDC_00575 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
EPKEEPDC_00576 1.78e-140 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
EPKEEPDC_00577 1.02e-191 ytpQ - - S - - - Belongs to the UPF0354 family
EPKEEPDC_00578 3.17e-75 ytpP - - CO - - - Thioredoxin
EPKEEPDC_00579 7.02e-103 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
EPKEEPDC_00580 2.15e-260 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
EPKEEPDC_00581 1.17e-67 ytzB - - S - - - small secreted protein
EPKEEPDC_00582 0.0 malS 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
EPKEEPDC_00583 3.07e-193 ytnP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
EPKEEPDC_00584 5.09e-155 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
EPKEEPDC_00585 9.51e-61 ytzH - - S - - - YtzH-like protein
EPKEEPDC_00586 3.02e-192 ytmP - - M - - - Phosphotransferase
EPKEEPDC_00587 0.0 amyX 3.2.1.41 CBM48,GH13 G ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
EPKEEPDC_00588 2.22e-231 ytlR - - I - - - Diacylglycerol kinase catalytic domain
EPKEEPDC_00589 4.92e-212 ytlQ - - - - - - -
EPKEEPDC_00590 2.38e-127 ytlP 3.1.4.58 - J ko:K01975 - ko00000,ko01000,ko03016 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EPKEEPDC_00591 3e-221 ytkP 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
EPKEEPDC_00592 0.0 ytjP 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Dipeptidase
EPKEEPDC_00593 1.73e-288 pbuO - - S ko:K06901 - ko00000,ko02000 permease
EPKEEPDC_00594 1.94e-252 ythQ - - U ko:K01992 - ko00000,ko00002,ko02000 Bacterial ABC transporter protein EcsB
EPKEEPDC_00595 9.39e-167 ythP - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
EPKEEPDC_00596 4.46e-46 ytzE - - K - - - COG1349 Transcriptional regulators of sugar metabolism
EPKEEPDC_00597 2.13e-169 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
EPKEEPDC_00598 0.0 ytgP - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EPKEEPDC_00599 3.87e-291 ytfP - - S ko:K07007 - ko00000 HI0933-like protein
EPKEEPDC_00600 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
EPKEEPDC_00601 2.14e-36 yteV - - S - - - Sporulation protein Cse60
EPKEEPDC_00602 1.05e-147 yteU - - S - - - Integral membrane protein
EPKEEPDC_00603 0.0 yteT - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
EPKEEPDC_00604 3.92e-93 yteS - - G - - - transport
EPKEEPDC_00605 1.68e-278 yteR 3.2.1.172 GH105 G ko:K15532 - ko00000,ko01000 unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
EPKEEPDC_00606 1.31e-220 lplB13 - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
EPKEEPDC_00607 0.0 ytdP - - K - - - Transcriptional regulator
EPKEEPDC_00608 0.0 - - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
EPKEEPDC_00609 6.19e-193 ytcP - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
EPKEEPDC_00610 2.21e-178 ytbQ 1.1.1.203, 1.1.1.388 - GM ko:K18981,ko:K19243 ko00030,ko00053,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00053,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 NAD dependent epimerase/dehydratase family
EPKEEPDC_00611 4.5e-279 bioI 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
EPKEEPDC_00612 4.57e-244 bioB 2.8.1.6 - H ko:K01012 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EPKEEPDC_00613 2.68e-159 bioD 6.3.3.3 - H ko:K01935 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EPKEEPDC_00614 2.58e-275 bioF 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
EPKEEPDC_00615 0.0 bioA 2.6.1.105, 2.6.1.62 - H ko:K00833,ko:K19563 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
EPKEEPDC_00616 2.24e-179 bioW 6.2.1.14 - H ko:K01906 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
EPKEEPDC_00617 1.13e-219 - - - S - - - Acetyl xylan esterase (AXE1)
EPKEEPDC_00618 1.78e-241 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
EPKEEPDC_00619 1.17e-308 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
EPKEEPDC_00620 1.66e-214 amyD - - P ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
EPKEEPDC_00621 7.65e-186 amyC - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
EPKEEPDC_00622 0.0 melA 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
EPKEEPDC_00623 1.22e-68 ytwF - - P - - - Sulfurtransferase
EPKEEPDC_00624 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
EPKEEPDC_00625 3.63e-72 ytvB - - S - - - Protein of unknown function (DUF4257)
EPKEEPDC_00626 1.56e-182 pfyP - - T - - - Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
EPKEEPDC_00627 7.01e-268 yttB - - EGP - - - Major facilitator superfamily
EPKEEPDC_00628 3.78e-76 yttA - - S - - - Pfam Transposase IS66
EPKEEPDC_00629 0.0 bceB - - V ko:K11632,ko:K19080 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter (permease)
EPKEEPDC_00630 3.14e-178 bceA - - V ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter, ATP-binding protein
EPKEEPDC_00631 8.4e-235 bceS 2.7.13.3 - T ko:K11629,ko:K19077 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 His Kinase A (phosphoacceptor) domain
EPKEEPDC_00632 1.46e-166 graR - - T ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01504,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EPKEEPDC_00633 1.39e-296 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
EPKEEPDC_00634 5.88e-163 ytrE - - V ko:K16920 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
EPKEEPDC_00635 3.13e-161 - - - - ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
EPKEEPDC_00636 9.47e-190 - - - P ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
EPKEEPDC_00637 5.96e-207 ytrB - - P ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
EPKEEPDC_00638 2.68e-87 ytrA - - K ko:K07979 - ko00000,ko03000 GntR family transcriptional regulator
EPKEEPDC_00640 1.27e-55 ytzC - - S - - - Protein of unknown function (DUF2524)
EPKEEPDC_00641 1.93e-243 ytqA - - S ko:K07139 - ko00000 Fe-S oxidoreductase
EPKEEPDC_00642 4.57e-135 ytqB - - J - - - Putative rRNA methylase
EPKEEPDC_00643 4.81e-276 ytpB 4.2.3.130 - S ko:K16188 - ko00000,ko01000 Tetraprenyl-beta-curcumene synthase
EPKEEPDC_00644 4.7e-192 ytpA 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Alpha beta hydrolase
EPKEEPDC_00645 8.35e-88 ytoA - - S - - - COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EPKEEPDC_00646 0.0 ytnA - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
EPKEEPDC_00647 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
EPKEEPDC_00648 9.2e-286 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EPKEEPDC_00649 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EPKEEPDC_00650 2.34e-51 ytmB - - S - - - Protein of unknown function (DUF2584)
EPKEEPDC_00651 7.79e-190 ytmA - - E - - - COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
EPKEEPDC_00652 1.87e-240 ytlA - - P ko:K02051 - ko00000,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
EPKEEPDC_00653 3.03e-184 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
EPKEEPDC_00654 1.32e-183 ytlD - - P ko:K02050 - ko00000,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
EPKEEPDC_00655 4.47e-113 ytkD 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
EPKEEPDC_00656 3.2e-81 ytkC - - S - - - Bacteriophage holin family
EPKEEPDC_00657 1.8e-99 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
EPKEEPDC_00659 4.78e-95 ytkA - - S - - - YtkA-like
EPKEEPDC_00660 8.36e-113 luxS 4.4.1.21 - T ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
EPKEEPDC_00661 1.27e-133 ytiB 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
EPKEEPDC_00662 1.44e-55 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
EPKEEPDC_00663 8.73e-315 ythA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
EPKEEPDC_00664 1.64e-238 ythB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG1294 Cytochrome bd-type quinol oxidase, subunit 2
EPKEEPDC_00665 2.43e-34 - - - S - - - Domain of Unknown Function (DUF1540)
EPKEEPDC_00666 9.24e-192 mntD - - P ko:K11709,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
EPKEEPDC_00667 6.11e-295 mntC - - P ko:K11705,ko:K11708,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
EPKEEPDC_00668 3.97e-175 mntB 3.6.3.35 - P ko:K02074,ko:K09820,ko:K11710,ko:K19973 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
EPKEEPDC_00669 3.77e-217 troA - - P ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
EPKEEPDC_00670 4.09e-272 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
EPKEEPDC_00671 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
EPKEEPDC_00672 3.45e-200 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EPKEEPDC_00673 9.85e-197 menH 4.2.99.20 - S ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
EPKEEPDC_00674 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EPKEEPDC_00675 0.0 menF 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
EPKEEPDC_00676 8.68e-169 yteA - - T - - - COG1734 DnaK suppressor protein
EPKEEPDC_00677 3.16e-192 ytdA 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
EPKEEPDC_00678 1.32e-306 ytcA 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EPKEEPDC_00679 4.12e-226 ytcB - - M - - - NAD-dependent epimerase dehydratase
EPKEEPDC_00680 6.86e-296 - - - M ko:K06338 - ko00000 Glycosyltransferase Family 4
EPKEEPDC_00682 2.82e-262 cotS - - S ko:K06337 - ko00000 Seems to be required for the assembly of the CotSA protein in spores
EPKEEPDC_00683 1.18e-274 cotSA - - M ko:K06338 - ko00000 Glycosyl transferases group 1
EPKEEPDC_00684 1.29e-260 cotI - - S ko:K06331 - ko00000 Spore coat protein
EPKEEPDC_00685 1.9e-99 ytaB - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 membrane
EPKEEPDC_00686 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
EPKEEPDC_00687 0.0 glgA 2.4.1.21 GT5 G ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
EPKEEPDC_00688 3.72e-238 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Glucose-1-phosphate adenylyltransferase, GlgD subunit
EPKEEPDC_00689 8.49e-265 glgC 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EPKEEPDC_00690 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EPKEEPDC_00712 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
EPKEEPDC_00713 2.52e-122 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
EPKEEPDC_00714 9.87e-122 - - - M - - - FR47-like protein
EPKEEPDC_00715 4.54e-258 yuaG - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 protein conserved in bacteria
EPKEEPDC_00716 1.68e-109 yuaF - - OU - - - Membrane protein implicated in regulation of membrane protease activity
EPKEEPDC_00717 1.95e-109 yuaE - - S - - - DinB superfamily
EPKEEPDC_00718 1.17e-136 yuaD - - - - - - -
EPKEEPDC_00719 4.26e-292 gbsB 1.1.1.1 - C ko:K11440 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
EPKEEPDC_00720 0.0 gbsA 1.2.1.8 - C ko:K00130 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
EPKEEPDC_00721 2.39e-121 yuaC - - K ko:K22109 - ko00000,ko03000 Belongs to the GbsR family
EPKEEPDC_00722 5.83e-118 yuaB - - - - - - -
EPKEEPDC_00723 1.06e-156 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
EPKEEPDC_00724 4.17e-298 - - - P ko:K03498 - ko00000,ko02000 Potassium
EPKEEPDC_00725 3.31e-52 yubF - - S - - - yiaA/B two helix domain
EPKEEPDC_00726 2.18e-195 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
EPKEEPDC_00727 0.0 yubD - - P - - - Major Facilitator Superfamily
EPKEEPDC_00728 2.29e-112 cdoA 1.13.11.20 - S ko:K00456 ko00270,ko00430,ko01100,map00270,map00430,map01100 ko00000,ko00001,ko01000 Cysteine dioxygenase type I
EPKEEPDC_00730 1.73e-182 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
EPKEEPDC_00731 8.95e-255 yubA - - S - - - transporter activity
EPKEEPDC_00732 7.48e-235 yulF - - S ko:K22230 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
EPKEEPDC_00733 9.8e-317 rhaA 2.7.1.5, 5.3.1.14 - G ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Belongs to the rhamnose isomerase family
EPKEEPDC_00734 2.86e-72 rhaM 5.1.3.32 - G ko:K03534 - ko00000,ko01000 Involved in the anomeric conversion of L-rhamnose
EPKEEPDC_00735 0.0 rhaB 2.7.1.5 - G ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
EPKEEPDC_00736 1.42e-172 yulB - - K ko:K02530,ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
EPKEEPDC_00737 0.0 yuxG - - IQ - - - Class II Aldolase and Adducin N-terminal domain
EPKEEPDC_00738 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
EPKEEPDC_00739 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
EPKEEPDC_00740 1.81e-299 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
EPKEEPDC_00741 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
EPKEEPDC_00742 6.15e-181 tgl 2.3.2.13 - H ko:K00686 - ko00000,ko01000 Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
EPKEEPDC_00743 5e-48 - - - - - - - -
EPKEEPDC_00744 3.63e-95 yugU - - S - - - Uncharacterised protein family UPF0047
EPKEEPDC_00745 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
EPKEEPDC_00746 8.8e-301 yugS - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
EPKEEPDC_00747 4.8e-150 yugP - - S ko:K06973 - ko00000 Zn-dependent protease
EPKEEPDC_00748 1.58e-50 - - - - - - - -
EPKEEPDC_00749 5.01e-69 mstX - - S - - - Membrane-integrating protein Mistic
EPKEEPDC_00750 3.56e-233 yugO - - P ko:K10716 - ko00000,ko02000 COG1226 Kef-type K transport systems
EPKEEPDC_00751 4.22e-95 yugN - - S - - - YugN-like family
EPKEEPDC_00753 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
EPKEEPDC_00754 9.22e-290 yugK - - C ko:K19955 - ko00000,ko01000 Dehydrogenase
EPKEEPDC_00755 2.85e-287 yugJ - - C ko:K19955 - ko00000,ko01000 oxidoreductases, Fe-dependent alcohol dehydrogenase family
EPKEEPDC_00756 2.21e-46 yuzA - - S ko:K09779 - ko00000 Domain of unknown function (DUF378)
EPKEEPDC_00757 5e-83 yugI - - J ko:K07570,ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
EPKEEPDC_00758 5.43e-255 yugH - - E ko:K10907 - ko00000,ko01000,ko01007 Aminotransferase
EPKEEPDC_00759 6.74e-112 alaR - - K - - - Transcriptional regulator
EPKEEPDC_00760 2.72e-198 yugF - - I - - - Hydrolase
EPKEEPDC_00761 8.84e-52 yugE - - S - - - Domain of unknown function (DUF1871)
EPKEEPDC_00762 3.46e-288 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
EPKEEPDC_00763 1.18e-293 kinB2 2.7.13.3 - T ko:K07697 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EPKEEPDC_00764 2.49e-91 kapB - - G ko:K06347 ko02020,map02020 ko00000,ko00001 Kinase associated protein B
EPKEEPDC_00765 6.98e-149 kapD - - L ko:K06348 - ko00000 the KinA pathway to sporulation
EPKEEPDC_00767 8.9e-242 yuxJ - - EGP - - - Major facilitator superfamily
EPKEEPDC_00768 0.0 pbpD 2.4.1.129, 3.4.16.4 GT51 M ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin-binding Protein
EPKEEPDC_00769 1.92e-97 yuxK - - S - - - protein conserved in bacteria
EPKEEPDC_00770 4.19e-113 yufK - - S - - - Family of unknown function (DUF5366)
EPKEEPDC_00771 0.0 malK 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
EPKEEPDC_00772 3.26e-162 dcuR - - T ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
EPKEEPDC_00773 1.51e-245 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
EPKEEPDC_00774 0.0 yufO 3.6.3.17 - S ko:K02056 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
EPKEEPDC_00775 6.39e-237 yufP - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
EPKEEPDC_00776 2.43e-215 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
EPKEEPDC_00777 7.99e-309 malP - - C ko:K11616 ko02020,map02020 ko00000,ko00001 COG3493 Na citrate symporter
EPKEEPDC_00778 1.73e-22 - - - - - - - -
EPKEEPDC_00779 0.0 mrpA - - CP ko:K05565 - ko00000,ko02000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
EPKEEPDC_00780 7.66e-91 mrpB - - P ko:K05566 - ko00000,ko02000 Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
EPKEEPDC_00781 1.72e-66 mrpC - - P ko:K05567 - ko00000,ko02000 Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
EPKEEPDC_00782 0.0 mrpD - - CP ko:K05568 - ko00000,ko02000 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
EPKEEPDC_00783 2.12e-102 mrpE - - P ko:K05569 - ko00000,ko02000 Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
EPKEEPDC_00784 2.23e-51 mrpF - - P ko:K05570 - ko00000,ko02000 Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
EPKEEPDC_00785 5.97e-79 mrpG - - P ko:K05571 - ko00000,ko02000 COG1320 Multisubunit Na H antiporter, MnhG subunit
EPKEEPDC_00786 1.11e-82 yuxO - - Q - - - protein, possibly involved in aromatic compounds catabolism
EPKEEPDC_00787 2.06e-150 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EPKEEPDC_00788 0.0 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EPKEEPDC_00790 5.4e-164 comQ - - H ko:K02251 ko02024,map02024 ko00000,ko00001,ko02044 Belongs to the FPP GGPP synthase family
EPKEEPDC_00791 6.29e-10 - - - S - - - DegQ (SacQ) family
EPKEEPDC_00792 4.38e-09 yuzC - - - - - - -
EPKEEPDC_00793 2.92e-298 yuxH - - T - - - signal transduction protein containing EAL and modified HD-GYP domains
EPKEEPDC_00794 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EPKEEPDC_00795 3.27e-134 pncA - - Q ko:K16788 - ko00000,ko02000 COG1335 Amidases related to nicotinamidase
EPKEEPDC_00796 8.92e-87 - - - S - - - Protein of unknown function (DUF1694)
EPKEEPDC_00797 1.63e-52 yueH - - S - - - YueH-like protein
EPKEEPDC_00798 7.15e-43 yueG - - S ko:K06299 - ko00000 Spore germination protein gerPA/gerPF
EPKEEPDC_00799 1.35e-244 yueF - - S - - - transporter activity
EPKEEPDC_00800 6.59e-92 - - - S - - - Protein of unknown function (DUF2283)
EPKEEPDC_00801 8.4e-33 - - - S - - - Protein of unknown function (DUF2642)
EPKEEPDC_00802 7.78e-125 yueE - - S ko:K06950 - ko00000 phosphohydrolase
EPKEEPDC_00803 5.85e-169 yueD 1.1.1.320 - IQ ko:K16216 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EPKEEPDC_00804 1.78e-96 yueC - - S - - - Family of unknown function (DUF5383)
EPKEEPDC_00805 0.0 yueB - - S - - - type VII secretion protein EsaA
EPKEEPDC_00806 0.0 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
EPKEEPDC_00807 8.62e-271 essB - - S - - - WXG100 protein secretion system (Wss), protein YukC
EPKEEPDC_00808 1.93e-54 yukD - - S - - - WXG100 protein secretion system (Wss), protein YukD
EPKEEPDC_00809 3.93e-60 yukE - - S - - - Belongs to the WXG100 family
EPKEEPDC_00810 4.7e-289 yukF - - QT - - - Transcriptional regulator
EPKEEPDC_00811 1.64e-261 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
EPKEEPDC_00812 1.2e-168 yukJ - - S - - - Uncharacterized conserved protein (DUF2278)
EPKEEPDC_00813 2.02e-47 mbtH - - S ko:K05375 ko00261,ko01130,map00261,map01130 ko00000,ko00001,ko00002 MbtH-like protein
EPKEEPDC_00814 0.0 dhbF - - Q ko:K04780 ko01053,map01053 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EPKEEPDC_00815 6.35e-228 dhbB 3.3.2.1, 6.3.2.14 - Q ko:K01252 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 Isochorismatase family
EPKEEPDC_00816 0.0 entE 2.7.7.58, 6.3.2.14 - Q ko:K02363,ko:K04783 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 2,3-dihydroxybenzoate-AMP ligase
EPKEEPDC_00817 3.34e-287 dhbC 5.4.4.2 - HQ ko:K02361 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
EPKEEPDC_00818 5.83e-178 dhbA 1.3.1.28 - IQ ko:K00216 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
EPKEEPDC_00819 8.58e-211 eSD - - S ko:K07017 - ko00000 Putative esterase
EPKEEPDC_00820 3.92e-156 yuiH - - S - - - Oxidoreductase molybdopterin binding domain
EPKEEPDC_00821 7.98e-123 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Biotin biosynthesis protein
EPKEEPDC_00822 3.65e-279 yuiF - - S ko:K07084 - ko00000,ko02000 antiporter
EPKEEPDC_00823 0.0 pepA 3.4.11.1 - E ko:K01255 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EPKEEPDC_00824 8.63e-102 yuiD - - S ko:K09775 - ko00000 protein conserved in bacteria
EPKEEPDC_00825 5.72e-122 yuiC - - S - - - protein conserved in bacteria
EPKEEPDC_00826 9.78e-47 yuiB - - S - - - Putative membrane protein
EPKEEPDC_00827 4.16e-301 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
EPKEEPDC_00828 1.16e-240 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 reductase
EPKEEPDC_00830 3.7e-234 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
EPKEEPDC_00831 1.16e-148 paiB - - K ko:K07734 - ko00000,ko03000 Putative FMN-binding domain
EPKEEPDC_00832 3.98e-115 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EPKEEPDC_00833 6.81e-83 erpA - - S ko:K13628 - ko00000,ko03016 Belongs to the HesB IscA family
EPKEEPDC_00834 4.55e-207 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EPKEEPDC_00835 3.61e-269 yutK - - F ko:K03317 - ko00000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EPKEEPDC_00836 1.74e-52 yuzB - - S - - - Belongs to the UPF0349 family
EPKEEPDC_00837 1.12e-253 yutJ 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
EPKEEPDC_00838 2.7e-74 yuzD - - S - - - protein conserved in bacteria
EPKEEPDC_00839 1.26e-47 yutI - - O - - - COG0694 Thioredoxin-like proteins and domains
EPKEEPDC_00840 0.0 yuxL 3.4.19.1 - EU ko:K01303 - ko00000,ko01000,ko01002 peptidase
EPKEEPDC_00841 2.11e-220 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
EPKEEPDC_00842 3.97e-252 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EPKEEPDC_00843 2.76e-306 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
EPKEEPDC_00844 8.97e-253 yutH - - S - - - Spore coat protein
EPKEEPDC_00845 2.26e-101 yutG 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
EPKEEPDC_00846 3.69e-183 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
EPKEEPDC_00847 1.96e-98 yutE - - S - - - Protein of unknown function DUF86
EPKEEPDC_00848 3.2e-63 yutD - - S - - - protein conserved in bacteria
EPKEEPDC_00849 2.71e-144 yutC - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
EPKEEPDC_00850 1.37e-215 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EPKEEPDC_00851 2.66e-252 lytH - - M ko:K21472 - ko00000,ko01000,ko01002,ko01011 Peptidase, M23
EPKEEPDC_00852 3.49e-169 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
EPKEEPDC_00853 1.39e-64 yunC - - S - - - Domain of unknown function (DUF1805)
EPKEEPDC_00854 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
EPKEEPDC_00855 6.51e-181 yunE - - S ko:K07090 - ko00000 membrane transporter protein
EPKEEPDC_00856 4.26e-220 yunF - - S - - - Protein of unknown function DUF72
EPKEEPDC_00857 3.06e-79 yunG - - - - - - -
EPKEEPDC_00858 0.0 allB 3.5.2.5 - F ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
EPKEEPDC_00859 0.0 pucR - - QT ko:K09684 - ko00000,ko03000 COG2508 Regulator of polyketide synthase expression
EPKEEPDC_00860 8.96e-293 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 Permease family
EPKEEPDC_00861 2.73e-284 pbuX - - F ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
EPKEEPDC_00862 0.0 - 1.7.3.3, 4.1.1.97 - Q ko:K16838 ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
EPKEEPDC_00863 2.09e-72 pucM 3.5.2.17 - S ko:K07127 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
EPKEEPDC_00864 0.000108 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
EPKEEPDC_00865 1.64e-120 - 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03518 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
EPKEEPDC_00866 0.0 pucD 1.17.1.4 - C ko:K00087 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
EPKEEPDC_00867 7.39e-189 pucC 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03519 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
EPKEEPDC_00868 7.22e-142 pucB 1.17.1.4, 2.7.7.76 - S ko:K00087,ko:K07141 ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120 ko00000,ko00001,ko00002,ko01000 MobA-like NTP transferase domain
EPKEEPDC_00869 5.06e-234 pucA 1.17.1.4 - O ko:K00087,ko:K07402 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
EPKEEPDC_00870 3.18e-301 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
EPKEEPDC_00871 8.34e-295 pucF 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
EPKEEPDC_00872 4.42e-216 bsn - - L - - - Ribonuclease
EPKEEPDC_00873 1.2e-262 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
EPKEEPDC_00874 1.89e-169 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
EPKEEPDC_00875 2.23e-198 - 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
EPKEEPDC_00876 1.6e-215 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
EPKEEPDC_00877 3.54e-199 yurN - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
EPKEEPDC_00878 1.66e-306 yurO - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
EPKEEPDC_00879 5.27e-235 frlB - - M ko:K10708 - ko00000,ko01000 Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
EPKEEPDC_00880 1.71e-87 yurQ - - L - - - COG0322 Nuclease subunit of the excinuclease complex
EPKEEPDC_00881 1.93e-266 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
EPKEEPDC_00883 3.35e-56 - - - - - - - -
EPKEEPDC_00884 5.06e-86 yurT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EPKEEPDC_00885 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 FeS cluster assembly
EPKEEPDC_00886 6.26e-101 nifU - - C ko:K04488 - ko00000 COG0822 NifU homolog involved in Fe-S cluster formation
EPKEEPDC_00887 1.14e-298 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EPKEEPDC_00888 7.12e-311 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
EPKEEPDC_00889 4.46e-182 sufC - - O ko:K09013 - ko00000,ko02000 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
EPKEEPDC_00890 1.56e-80 yurZ - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EPKEEPDC_00891 5.86e-189 metQ - - P ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
EPKEEPDC_00892 6.5e-126 metI - - P ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2011 ABC-type metal ion transport system, permease component
EPKEEPDC_00893 2.15e-236 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EPKEEPDC_00894 1.53e-74 yusD - - S - - - SCP-2 sterol transfer family
EPKEEPDC_00895 6.7e-72 yusE - - CO - - - Thioredoxin
EPKEEPDC_00896 7.62e-97 yusF - - L ko:K07476 - ko00000 COG1658 Small primase-like proteins (Toprim domain)
EPKEEPDC_00897 7.34e-54 yusG - - S - - - Protein of unknown function (DUF2553)
EPKEEPDC_00898 5.91e-85 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
EPKEEPDC_00899 1.01e-83 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
EPKEEPDC_00900 0.0 fadE 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
EPKEEPDC_00901 1.34e-278 fadA 2.3.1.16 - I ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the thiolase family
EPKEEPDC_00902 0.0 fadN 1.1.1.35 - I ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 ko00000,ko00001,ko00002,ko01000 3-hydroxyacyl-CoA dehydrogenase
EPKEEPDC_00903 1.11e-13 - - - S - - - YuzL-like protein
EPKEEPDC_00904 1.21e-211 fadM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
EPKEEPDC_00905 2.23e-54 - - - - - - - -
EPKEEPDC_00906 8.66e-70 yusN - - M - - - Coat F domain
EPKEEPDC_00907 6.35e-98 yusO - - K - - - Iron dependent repressor, N-terminal DNA binding domain
EPKEEPDC_00908 0.0 yusP - - P - - - Major facilitator superfamily
EPKEEPDC_00909 4.86e-84 yusQ - - S - - - Tautomerase enzyme
EPKEEPDC_00910 7.05e-138 yusR 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
EPKEEPDC_00911 6.91e-203 gltR - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
EPKEEPDC_00912 3.01e-63 yusU - - S - - - Protein of unknown function (DUF2573)
EPKEEPDC_00913 8.74e-196 yusV 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
EPKEEPDC_00914 3.48e-88 - - - S - - - YusW-like protein
EPKEEPDC_00915 0.0 pepF2 - - E - - - COG1164 Oligoendopeptidase F
EPKEEPDC_00916 4.49e-196 yusZ - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
EPKEEPDC_00917 2.15e-104 fri - - P ko:K04047 - ko00000,ko03036 Ferritin-like domain
EPKEEPDC_00918 1.12e-304 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EPKEEPDC_00919 2.23e-164 cssR - - T ko:K07770 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EPKEEPDC_00920 2.77e-316 cssS 2.7.13.3 - T ko:K07650 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EPKEEPDC_00921 3.06e-204 yuxN - - K - - - Transcriptional regulator
EPKEEPDC_00922 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
EPKEEPDC_00923 4.48e-34 - - - S - - - Protein of unknown function (DUF3970)
EPKEEPDC_00924 0.0 gerAA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
EPKEEPDC_00925 3.94e-251 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
EPKEEPDC_00926 3.05e-243 gerAC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination B3/ GerAC like, C-terminal
EPKEEPDC_00927 4.46e-139 vraR - - KT ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EPKEEPDC_00928 2.35e-245 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EPKEEPDC_00929 7.65e-164 - - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
EPKEEPDC_00930 1.41e-172 liaG - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
EPKEEPDC_00931 4.05e-142 liaH - - KT ko:K03969,ko:K11620 ko02020,map02020 ko00000,ko00001,ko00002 COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
EPKEEPDC_00932 1.51e-82 liaI - - S ko:K11619 ko02020,map02020 ko00000,ko00001,ko00002 membrane
EPKEEPDC_00933 6.23e-286 yvqJ - - EGP - - - COG0477 Permeases of the major facilitator superfamily
EPKEEPDC_00934 1.2e-129 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Adenosyltransferase
EPKEEPDC_00935 3.14e-310 yvrA 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
EPKEEPDC_00936 1.1e-235 btuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EPKEEPDC_00937 2.98e-218 btuF - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
EPKEEPDC_00938 2.12e-181 yvrD - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
EPKEEPDC_00939 1.32e-219 yvrE - - G ko:K14274 ko00040,map00040 ko00000,ko00001,ko01000 SMP-30/Gluconolaconase/LRE-like region
EPKEEPDC_00940 0.0 yvrG - - T - - - Histidine kinase
EPKEEPDC_00941 1.1e-170 yvrH - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EPKEEPDC_00942 6.16e-33 - - - - - - - -
EPKEEPDC_00943 7.02e-128 yvrI - - K ko:K03093 - ko00000,ko03021 RNA polymerase
EPKEEPDC_00944 3.46e-26 - - - S - - - YvrJ protein family
EPKEEPDC_00945 9.23e-292 oxdC 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
EPKEEPDC_00946 1.16e-84 yvrL - - S - - - Regulatory protein YrvL
EPKEEPDC_00947 2.21e-272 yvrN - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
EPKEEPDC_00948 3.82e-158 yvrO - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EPKEEPDC_00949 3.61e-231 - - - M ko:K02005 - ko00000 Efflux transporter rnd family, mfp subunit
EPKEEPDC_00950 2.92e-191 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
EPKEEPDC_00951 4.78e-226 fhuG - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EPKEEPDC_00952 2e-235 fhuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EPKEEPDC_00953 4.45e-225 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
EPKEEPDC_00955 0.0 yvsH - - E ko:K03294,ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
EPKEEPDC_00956 9.37e-23 - - - S ko:K06427 - ko00000 Small spore protein J (Spore_SspJ)
EPKEEPDC_00957 2.38e-109 yvsG - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
EPKEEPDC_00958 0.0 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
EPKEEPDC_00959 6.98e-212 yvgK - - P ko:K07219 - ko00000 COG1910 Periplasmic molybdate-binding protein domain
EPKEEPDC_00960 1.22e-174 modA - - P ko:K02020 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0725 ABC-type molybdate transport system, periplasmic component
EPKEEPDC_00961 2.89e-152 modB - - P ko:K02018 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4149 ABC-type molybdate transport system, permease component
EPKEEPDC_00962 6.19e-201 yvgN - - S - - - reductase
EPKEEPDC_00963 7.97e-113 yvgO - - - - - - -
EPKEEPDC_00964 0.0 yvgP - - P ko:K03316 - ko00000 COG0025 NhaP-type Na H and K H antiporters
EPKEEPDC_00965 0.0 cysI 1.8.1.2, 1.8.7.1 - P ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
EPKEEPDC_00966 0.0 cysJ 1.8.1.2 - P ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EPKEEPDC_00967 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
EPKEEPDC_00969 2.34e-139 yvgT - - S - - - membrane
EPKEEPDC_00970 1.99e-95 bdbC - - O ko:K03611 - ko00000,ko03110 Required for disulfide bond formation in some proteins
EPKEEPDC_00971 3.45e-137 bdbD - - O - - - Thioredoxin
EPKEEPDC_00972 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
EPKEEPDC_00973 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
EPKEEPDC_00974 3.02e-40 copZ - - P ko:K07213 ko04978,map04978 ko00000,ko00001 Copper resistance protein CopZ
EPKEEPDC_00975 6.89e-65 csoR - - S ko:K21600 - ko00000,ko03000 transcriptional
EPKEEPDC_00976 3.3e-246 yvaA 1.1.1.371 - S ko:K16044 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
EPKEEPDC_00977 2.08e-153 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EPKEEPDC_00978 0.0 - - - S - - - Fusaric acid resistance protein-like
EPKEEPDC_00979 2.02e-97 yvaD - - S - - - Family of unknown function (DUF5360)
EPKEEPDC_00980 5.85e-70 yvaE - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
EPKEEPDC_00981 1.66e-126 - - - K - - - Bacterial regulatory proteins, tetR family
EPKEEPDC_00982 1.13e-181 yvaG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
EPKEEPDC_00984 2.4e-107 smpB - - O ko:K03664 - ko00000 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EPKEEPDC_00985 0.0 rnr - - K ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
EPKEEPDC_00986 3.43e-183 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Carboxylesterase
EPKEEPDC_00987 1.87e-35 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
EPKEEPDC_00988 3.69e-181 yvaM 1.11.1.10 - S ko:K00433 - ko00000,ko01000 Serine aminopeptidase, S33
EPKEEPDC_00989 3.44e-48 yvzC - - K - - - transcriptional
EPKEEPDC_00990 4.77e-91 yvaO - - K ko:K22299 - ko00000,ko03000 transcriptional
EPKEEPDC_00991 7.76e-89 yvaO - - K ko:K22299 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
EPKEEPDC_00992 3.85e-72 yvaP - - K - - - transcriptional
EPKEEPDC_00993 0.0 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
EPKEEPDC_00994 2.26e-144 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
EPKEEPDC_00995 2.27e-218 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
EPKEEPDC_00996 1.55e-142 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
EPKEEPDC_00997 7.34e-271 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
EPKEEPDC_00998 6.63e-122 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
EPKEEPDC_00999 5.59e-136 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
EPKEEPDC_01000 1.23e-221 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
EPKEEPDC_01001 1.61e-144 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
EPKEEPDC_01002 1.26e-266 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
EPKEEPDC_01003 8.29e-129 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
EPKEEPDC_01004 3.94e-135 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
EPKEEPDC_01005 2.96e-145 yvbH - - S - - - YvbH-like oligomerisation region
EPKEEPDC_01006 2.28e-156 yvbI - - M - - - Membrane
EPKEEPDC_01007 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
EPKEEPDC_01008 9.77e-106 yvbK - - K - - - acetyltransferase
EPKEEPDC_01009 1.38e-309 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
EPKEEPDC_01010 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and
EPKEEPDC_01011 2.12e-176 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
EPKEEPDC_01012 1.97e-277 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
EPKEEPDC_01013 5.72e-238 gapA 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
EPKEEPDC_01014 5.69e-236 cggR - - K ko:K05311 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
EPKEEPDC_01015 0.0 araE - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
EPKEEPDC_01016 4.32e-258 araR - - K ko:K02103 - ko00000,ko03000 transcriptional
EPKEEPDC_01017 8.53e-245 yvbT - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EPKEEPDC_01018 3.31e-204 yvbU - - K - - - Transcriptional regulator
EPKEEPDC_01019 1.6e-197 yvbV - - EG - - - EamA-like transporter family
EPKEEPDC_01020 7.07e-307 yvbW - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
EPKEEPDC_01021 1.22e-248 - - - S - - - Glycosyl hydrolase
EPKEEPDC_01022 1.14e-169 lutC - - S ko:K00782 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
EPKEEPDC_01023 0.0 lutB - - C ko:K18929 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
EPKEEPDC_01024 1.06e-173 lutA - - C ko:K18928 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
EPKEEPDC_01025 3.88e-57 - - - S - - - Protein of unknown function (DUF2812)
EPKEEPDC_01026 4.23e-42 - - - K - - - Transcriptional regulator PadR-like family
EPKEEPDC_01027 7.23e-135 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EPKEEPDC_01028 1.54e-251 yvfT 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EPKEEPDC_01029 5.85e-170 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
EPKEEPDC_01030 2.9e-200 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
EPKEEPDC_01032 2.08e-200 rsbQ - - S ko:K19707 - ko00000,ko03021 Alpha/beta hydrolase family
EPKEEPDC_01033 1.52e-265 - 3.1.3.3 - T ko:K07315 - ko00000,ko01000,ko03021 response regulator
EPKEEPDC_01034 0.0 ganB 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
EPKEEPDC_01035 0.0 lacA 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 beta-galactosidase
EPKEEPDC_01036 3.82e-194 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
EPKEEPDC_01037 1.3e-301 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
EPKEEPDC_01038 4.62e-292 cycB - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
EPKEEPDC_01039 2e-236 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
EPKEEPDC_01040 6.85e-146 yvfI - - K ko:K05799 - ko00000,ko03000 COG2186 Transcriptional regulators
EPKEEPDC_01041 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
EPKEEPDC_01042 7.87e-303 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
EPKEEPDC_01043 5.69e-44 yvfG - - S - - - YvfG protein
EPKEEPDC_01044 4.69e-235 epsO - - GM ko:K19431 - ko00000,ko01000 Exopolysaccharide biosynthesis protein
EPKEEPDC_01045 7.46e-279 epsN - - E ko:K19430 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
EPKEEPDC_01046 3.33e-76 epsM - - GM ko:K19429 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
EPKEEPDC_01047 9.14e-139 epsL - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 COG2148 Sugar transferases involved in lipopolysaccharide synthesis
EPKEEPDC_01048 0.0 epsK - - S ko:K19418 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EPKEEPDC_01049 3.5e-248 epsJ - GT2 S ko:K19427 - ko00000,ko01000 COG0463 Glycosyltransferases involved in cell wall biogenesis
EPKEEPDC_01050 1.57e-258 epsI - - GM ko:K19426 - ko00000,ko01000 pyruvyl transferase
EPKEEPDC_01051 1.22e-248 epsH - GT2 S ko:K19425 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
EPKEEPDC_01052 8.82e-265 epsG - - S ko:K19419 - ko00000,ko02000 EpsG family
EPKEEPDC_01053 7.18e-278 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
EPKEEPDC_01054 1.25e-201 epsE - GT2 M ko:K19423 - ko00000,ko01000,ko01003 COG0463 Glycosyltransferases involved in cell wall biogenesis
EPKEEPDC_01055 7.45e-280 epsD - GT4 M ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like
EPKEEPDC_01056 0.0 capD - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
EPKEEPDC_01057 3.77e-148 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
EPKEEPDC_01058 1.61e-157 epsA - - M ko:K19420 - ko00000 biosynthesis protein
EPKEEPDC_01059 3.57e-98 - - - K ko:K19417 - ko00000,ko03000 transcriptional
EPKEEPDC_01060 0.0 pnbA - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
EPKEEPDC_01062 5.4e-120 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
EPKEEPDC_01063 7.42e-95 - - - S - - - Protein of unknown function (DUF3237)
EPKEEPDC_01064 1.19e-160 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
EPKEEPDC_01065 0.0 pbpE - - V - - - Beta-lactamase
EPKEEPDC_01066 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 levansucrase activity
EPKEEPDC_01067 0.0 sacC3 3.2.1.65 GH32 G ko:K01212 ko00500,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
EPKEEPDC_01068 0.0 ybeC - - E - - - amino acid
EPKEEPDC_01069 2.75e-136 yvdT_1 - - K - - - Transcriptional regulator
EPKEEPDC_01070 3.65e-67 yvdS - - P ko:K18924 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
EPKEEPDC_01071 2.08e-66 yvdR - - P ko:K11741 - ko00000,ko02000 Small Multidrug Resistance protein
EPKEEPDC_01072 2.63e-120 yvdQ - - S - - - Protein of unknown function (DUF3231)
EPKEEPDC_01074 8.17e-135 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
EPKEEPDC_01075 3.09e-146 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
EPKEEPDC_01076 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
EPKEEPDC_01077 0.0 yvdK 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycoside hydrolase, family 65
EPKEEPDC_01078 8.09e-202 malA - - S - - - Protein of unknown function (DUF1189)
EPKEEPDC_01079 3.96e-189 malD - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
EPKEEPDC_01080 1.01e-309 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
EPKEEPDC_01081 6.95e-301 mdxE - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
EPKEEPDC_01082 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, N-terminal ig-like domain
EPKEEPDC_01083 1.54e-221 yvdE - - K - - - Transcriptional regulator
EPKEEPDC_01084 2.66e-137 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
EPKEEPDC_01085 7.84e-71 yvdC - - S - - - MazG nucleotide pyrophosphohydrolase domain
EPKEEPDC_01086 0.0 yvdB - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
EPKEEPDC_01087 1.03e-134 yvdA 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
EPKEEPDC_01088 2.7e-233 yvcT 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EPKEEPDC_01089 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
EPKEEPDC_01090 4.46e-181 yxdL_2 - - V ko:K02003,ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
EPKEEPDC_01091 3.24e-250 yvcQ - - T - - - His Kinase A (phosphoacceptor) domain
EPKEEPDC_01092 3.84e-171 yvcP - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EPKEEPDC_01093 1.32e-43 - - - - - - - -
EPKEEPDC_01094 1.33e-181 yvcN 2.3.1.118 - Q ko:K00675 - ko00000,ko01000 Belongs to the arylamine N-acetyltransferase family
EPKEEPDC_01095 3.92e-50 crh - - G ko:K11184 - ko00000 Phosphocarrier protein Chr
EPKEEPDC_01096 1.04e-219 whiA - - K ko:K09762 - ko00000 May be required for sporulation
EPKEEPDC_01097 6.72e-227 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
EPKEEPDC_01098 2.09e-213 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
EPKEEPDC_01099 2.39e-117 yvcI 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
EPKEEPDC_01100 1.18e-225 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
EPKEEPDC_01101 1.89e-185 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 protein conserved in bacteria
EPKEEPDC_01102 0.0 yvcD - - S - - - COG0457 FOG TPR repeat
EPKEEPDC_01103 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
EPKEEPDC_01105 0.0 - - - - - - - -
EPKEEPDC_01106 7.43e-171 - - - - - - - -
EPKEEPDC_01107 4.86e-142 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the PRA-CH family
EPKEEPDC_01108 5.63e-176 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
EPKEEPDC_01109 1.27e-164 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EPKEEPDC_01110 5.24e-143 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EPKEEPDC_01111 1.17e-137 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
EPKEEPDC_01112 3e-291 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EPKEEPDC_01113 1.06e-147 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
EPKEEPDC_01114 2.42e-281 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EPKEEPDC_01115 1.76e-178 yvpB - - NU - - - protein conserved in bacteria
EPKEEPDC_01116 3.15e-153 - 4.2.2.10, 4.2.2.2 - G ko:K19551 ko00040,map00040 ko00000,ko00001,ko01000 Pectate lyase
EPKEEPDC_01117 5.94e-118 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
EPKEEPDC_01118 3.05e-153 ppaX 3.6.1.1 - S ko:K06019 ko00190,map00190 ko00000,ko00001,ko01000 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
EPKEEPDC_01119 2.06e-208 yvoD - - P - - - COG0370 Fe2 transport system protein B
EPKEEPDC_01120 2.61e-194 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EPKEEPDC_01121 3.62e-217 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EPKEEPDC_01122 9.81e-279 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
EPKEEPDC_01123 1.43e-164 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
EPKEEPDC_01124 3.02e-171 yvoA - - K ko:K03710 - ko00000,ko03000 transcriptional
EPKEEPDC_01125 0.0 yvnB - - Q - - - Calcineurin-like phosphoesterase
EPKEEPDC_01126 4.06e-94 yvnA - - K - - - helix_turn_helix multiple antibiotic resistance protein
EPKEEPDC_01127 2.45e-288 cypX 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
EPKEEPDC_01128 8.35e-176 yvmC 2.3.2.22 - S ko:K17485 - ko00000,ko01000 Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
EPKEEPDC_01129 6.2e-114 yvmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
EPKEEPDC_01130 4.96e-271 yvmA - - EGP - - - Major Facilitator Superfamily
EPKEEPDC_01131 3.8e-66 yvlD - - S ko:K08972 - ko00000 Membrane
EPKEEPDC_01132 1.5e-36 yvlC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
EPKEEPDC_01133 9.59e-220 yvlB - - S - - - Putative adhesin
EPKEEPDC_01134 9.45e-64 yvlA - - - - - - -
EPKEEPDC_01135 2.25e-45 yvkN - - - - - - -
EPKEEPDC_01136 3.03e-147 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EPKEEPDC_01137 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
EPKEEPDC_01138 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
EPKEEPDC_01139 2.54e-42 csbA - - S - - - protein conserved in bacteria
EPKEEPDC_01140 0.0 yvkC 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Phosphotransferase
EPKEEPDC_01141 1.43e-131 yvkB - - K - - - Transcriptional regulator
EPKEEPDC_01142 3.03e-295 yvkA - - P - - - -transporter
EPKEEPDC_01143 3.17e-280 minJ - - O - - - COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EPKEEPDC_01144 1.38e-73 swrA - - S - - - Swarming motility protein
EPKEEPDC_01145 0.0 ctpB 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
EPKEEPDC_01146 5.45e-199 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
EPKEEPDC_01147 1.5e-159 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
EPKEEPDC_01148 2.19e-71 cccB - - C ko:K12263,ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
EPKEEPDC_01149 6.5e-185 yvjA - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
EPKEEPDC_01150 2e-232 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EPKEEPDC_01151 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
EPKEEPDC_01152 1.73e-132 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EPKEEPDC_01153 2.46e-67 - - - - - - - -
EPKEEPDC_01154 8.69e-09 fliT - - S ko:K02423 ko02040,map02040 ko00000,ko00001,ko02035 bacterial-type flagellum organization
EPKEEPDC_01155 5.15e-91 fliS - - N ko:K02422 ko02040,map02040 ko00000,ko00001,ko02035 flagellar protein FliS
EPKEEPDC_01156 0.0 fliD - - N ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
EPKEEPDC_01157 9.02e-76 flaG - - N ko:K06603 - ko00000,ko02035 flagellar protein FlaG
EPKEEPDC_01158 1.44e-104 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EPKEEPDC_01159 2.58e-41 csrA - - T ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 ko00000,ko00001,ko03019 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
EPKEEPDC_01160 1.23e-96 fliW - - S ko:K13626 - ko00000,ko02035 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
EPKEEPDC_01161 1.7e-92 yviE - - - - - - -
EPKEEPDC_01162 3.8e-197 flgL - - N ko:K02397 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the bacterial flagellin family
EPKEEPDC_01163 0.0 flgK - - N ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 flagellar hook-associated protein
EPKEEPDC_01164 7.06e-102 yvyG - - NOU - - - FlgN protein
EPKEEPDC_01165 8.72e-53 flgM - - KNU ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 ko00000,ko00001,ko02035 Negative regulator of flagellin synthesis
EPKEEPDC_01166 1.83e-96 yvyF - - S - - - flagellar protein
EPKEEPDC_01167 6.48e-162 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Phosphoribosyl transferase domain
EPKEEPDC_01168 5.13e-61 comFB - - S ko:K02241 - ko00000,ko00002,ko02044 Late competence development protein ComFB
EPKEEPDC_01169 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EPKEEPDC_01170 4.16e-197 degV - - S - - - protein conserved in bacteria
EPKEEPDC_01171 7.16e-163 degU - - KT ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EPKEEPDC_01172 2.94e-247 degS 2.7.13.3 - T ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
EPKEEPDC_01173 2.41e-155 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 Domain of unknown function (DUF1949)
EPKEEPDC_01174 3.12e-222 yvhJ - - K - - - Transcriptional regulator
EPKEEPDC_01175 2.1e-231 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
EPKEEPDC_01176 4.13e-297 tuaH - - M ko:K16699 - ko00000,ko01000,ko01003 Teichuronic acid biosynthesis glycosyltransferase tuaH
EPKEEPDC_01177 6.92e-186 tuaG - GT2 M ko:K16698 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
EPKEEPDC_01178 1.42e-147 tuaF - - M ko:K16706 - ko00000 protein involved in exopolysaccharide biosynthesis
EPKEEPDC_01179 0.0 tuaE - - M ko:K16705 - ko00000 Teichuronic acid biosynthesis protein
EPKEEPDC_01180 0.0 tuaD 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EPKEEPDC_01181 1.19e-280 tuaC - GT4 GM ko:K16697 - ko00000,ko01000,ko01003 Teichuronic acid
EPKEEPDC_01182 1.03e-315 tuaB - - S ko:K03328,ko:K16694,ko:K16695 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EPKEEPDC_01183 1.49e-143 tuaA - - M - - - COG2148 Sugar transferases involved in lipopolysaccharide synthesis
EPKEEPDC_01184 5.9e-117 - - - M - - - Glycosyltransferase like family 2
EPKEEPDC_01185 5.81e-261 lytC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
EPKEEPDC_01186 0.0 lytB - - D - - - Stage II sporulation protein
EPKEEPDC_01187 4.58e-16 - - - - - - - -
EPKEEPDC_01188 1.16e-211 lytR - - K - - - May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
EPKEEPDC_01189 2.03e-272 mnaA 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
EPKEEPDC_01190 2.09e-103 - - - M - - - Glycosyltransferase like family 2
EPKEEPDC_01191 4.85e-118 - - - M - - - Glycosyl transferases group 1
EPKEEPDC_01194 1.25e-204 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
EPKEEPDC_01195 0.0 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
EPKEEPDC_01196 1.08e-164 tagG - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
EPKEEPDC_01197 5.55e-66 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase
EPKEEPDC_01198 1.02e-155 - - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
EPKEEPDC_01199 6.23e-205 - 2.7.8.14, 2.7.8.47 - M ko:K18704 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
EPKEEPDC_01200 7.2e-113 tagA 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
EPKEEPDC_01201 5.36e-121 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EPKEEPDC_01202 2.07e-134 tarI 2.7.7.40, 2.7.7.60 - I ko:K00991,ko:K21030 ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
EPKEEPDC_01203 5.68e-186 tarJ 1.1.1.137, 1.1.1.405 - E ko:K05352,ko:K21680 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
EPKEEPDC_01204 2.47e-109 tarK 2.7.8.14, 2.7.8.46, 2.7.8.47 - M ko:K18704,ko:K21592 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
EPKEEPDC_01205 1.42e-235 tarL 2.7.8.14, 2.7.8.47 - M ko:K18704 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
EPKEEPDC_01206 0.0 lytD 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
EPKEEPDC_01207 1.84e-238 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
EPKEEPDC_01208 1.55e-310 gerBA - - EG ko:K06291,ko:K06310 - ko00000 Spore germination protein
EPKEEPDC_01209 2.06e-239 gerBB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
EPKEEPDC_01210 8.28e-253 gerBC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination protein
EPKEEPDC_01211 9.1e-315 ywtG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
EPKEEPDC_01212 1.42e-220 ywtF_2 - - K - - - Transcriptional regulator
EPKEEPDC_01213 2.32e-201 ywtE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
EPKEEPDC_01214 1.37e-304 pgdS - - M - - - COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
EPKEEPDC_01215 2.29e-29 ywtC - - - - - - -
EPKEEPDC_01216 4.21e-251 capA - - M ko:K07282 - ko00000 enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
EPKEEPDC_01217 8.44e-91 capC - - S ko:K22116 - ko00000 biosynthesis protein
EPKEEPDC_01218 1.46e-283 capB - - M ko:K01932 - ko00000,ko01000 COG0769 UDP-N-acetylmuramyl tripeptide synthase
EPKEEPDC_01219 2.68e-227 rbsR - - K ko:K02529 - ko00000,ko03000 transcriptional
EPKEEPDC_01220 5.92e-203 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EPKEEPDC_01221 4.61e-84 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
EPKEEPDC_01222 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
EPKEEPDC_01223 3.35e-203 rbsC - - G ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
EPKEEPDC_01224 3.68e-203 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 COG1879 ABC-type sugar transport system, periplasmic component
EPKEEPDC_01225 1.55e-116 batE - - T - - - Sh3 type 3 domain protein
EPKEEPDC_01226 2.17e-62 ywsA - - S - - - Protein of unknown function (DUF3892)
EPKEEPDC_01227 3.57e-125 ywrO - - S - - - NADPH-quinone reductase (modulator of drug activity B)
EPKEEPDC_01228 6.15e-186 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
EPKEEPDC_01229 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
EPKEEPDC_01230 3.36e-218 alsR - - K - - - LysR substrate binding domain
EPKEEPDC_01231 1.32e-278 ywrK - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EPKEEPDC_01232 3.56e-161 ywrJ - - - - - - -
EPKEEPDC_01233 1.99e-171 cotB - - - ko:K06325 - ko00000 -
EPKEEPDC_01234 2.08e-265 cotH - - M ko:K06330 - ko00000 Spore Coat
EPKEEPDC_01235 3.41e-17 - - - - - - - -
EPKEEPDC_01236 6.18e-143 ywrF - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EPKEEPDC_01237 1.13e-70 - - - S - - - Domain of unknown function (DUF4181)
EPKEEPDC_01238 0.0 ywrD 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
EPKEEPDC_01239 2.79e-107 ywrC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
EPKEEPDC_01240 4.53e-132 ywrB - - P ko:K07240 - ko00000,ko02000 Chromate transporter
EPKEEPDC_01241 6.07e-114 ywrA - - P ko:K07240 - ko00000,ko02000 COG2059 Chromate transport protein ChrA
EPKEEPDC_01243 1.24e-149 nfi 3.1.21.7 - L ko:K05982 - ko00000,ko01000,ko03400 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
EPKEEPDC_01245 1.01e-302 ywqJ - - S - - - Pre-toxin TG
EPKEEPDC_01246 1.04e-51 ywqI - - S - - - Family of unknown function (DUF5344)
EPKEEPDC_01248 3.59e-197 ywqG - - S - - - Domain of unknown function (DUF1963)
EPKEEPDC_01249 7.72e-312 ywqF 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EPKEEPDC_01250 2.05e-179 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 COG4464 Capsular polysaccharide biosynthesis protein
EPKEEPDC_01251 1.06e-152 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
EPKEEPDC_01252 5.33e-163 ywqC - - M ko:K19420 - ko00000 biosynthesis protein
EPKEEPDC_01253 3.6e-25 - - - - - - - -
EPKEEPDC_01254 0.0 ywqB - - S - - - SWIM zinc finger
EPKEEPDC_01255 0.0 ywqA - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
EPKEEPDC_01256 5.07e-200 ywpJ 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
EPKEEPDC_01257 4.82e-180 glcR - - K ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
EPKEEPDC_01258 8.53e-76 ssbB - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
EPKEEPDC_01259 5.26e-88 ywpG - - - - - - -
EPKEEPDC_01260 8.81e-89 ywpF - - S - - - YwpF-like protein
EPKEEPDC_01261 5.85e-107 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
EPKEEPDC_01262 0.0 - - - M - - - cell wall anchor domain
EPKEEPDC_01263 1.68e-221 M1-574 - - T - - - Transcriptional regulatory protein, C terminal
EPKEEPDC_01264 0.0 ywpD - - T - - - Histidine kinase
EPKEEPDC_01265 1.32e-76 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
EPKEEPDC_01266 6.89e-107 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
EPKEEPDC_01267 8.66e-254 rapD - - S ko:K06362 - ko00000,ko01000 aspartate phosphatase
EPKEEPDC_01268 1.17e-181 flhP - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
EPKEEPDC_01269 1.77e-172 flhO - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
EPKEEPDC_01270 1.75e-231 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein
EPKEEPDC_01271 4.88e-59 spoIIID - - K ko:K06283 - ko00000,ko03000 Stage III sporulation protein D
EPKEEPDC_01272 8.45e-92 - - - K - - - COG1846 Transcriptional regulators
EPKEEPDC_01273 1.37e-269 ywoG - - EGP - - - COG0477 Permeases of the major facilitator superfamily
EPKEEPDC_01275 1.97e-310 ywoF - - P - - - Right handed beta helix region
EPKEEPDC_01276 0.0 - - - FH ko:K03457,ko:K10975 - ko00000,ko02000 COG1953 Cytosine uracil thiamine allantoin permeases
EPKEEPDC_01277 4.62e-308 ywoD - - EGP - - - Major facilitator superfamily
EPKEEPDC_01278 6.05e-133 yjgF - - Q - - - Isochorismatase family
EPKEEPDC_01279 5.04e-101 - - - - - - - -
EPKEEPDC_01280 1.6e-288 nrgA - - P ko:K03320 - ko00000,ko02000 Ammonium transporter
EPKEEPDC_01281 4.51e-77 nrgB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
EPKEEPDC_01282 1.21e-134 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 COG0671 Membrane-associated phospholipid phosphatase
EPKEEPDC_01283 1.98e-92 ywnJ - - S - - - VanZ like family
EPKEEPDC_01284 1.85e-161 spoIIQ - - M ko:K06386 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
EPKEEPDC_01285 6.31e-116 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 COG1247 Sortase and related acyltransferases
EPKEEPDC_01286 6.55e-22 ywnC - - S - - - Family of unknown function (DUF5362)
EPKEEPDC_01287 7.07e-92 ywnF - - S - - - Family of unknown function (DUF5392)
EPKEEPDC_01288 0.0 ywnE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EPKEEPDC_01289 4.65e-182 mta - - K ko:K21743 - ko00000,ko03000 transcriptional
EPKEEPDC_01290 8.72e-78 ywnC - - S - - - Family of unknown function (DUF5362)
EPKEEPDC_01291 1.51e-147 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
EPKEEPDC_01292 1.08e-83 ywnA - - K - - - Transcriptional regulator
EPKEEPDC_01293 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
EPKEEPDC_01294 1.12e-83 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
EPKEEPDC_01295 8.2e-68 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
EPKEEPDC_01296 2.73e-28 - - - E ko:K11963 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
EPKEEPDC_01297 1.11e-21 csbD - - K - - - CsbD-like
EPKEEPDC_01298 1.66e-109 ywmF - - S - - - Peptidase M50
EPKEEPDC_01299 3.1e-129 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
EPKEEPDC_01300 1.08e-245 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EPKEEPDC_01301 9.06e-187 fdhD - - C ko:K02379 - ko00000 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EPKEEPDC_01303 1.02e-155 ywmD - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
EPKEEPDC_01304 1.89e-157 ywmC - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
EPKEEPDC_01305 9.77e-234 spoIID - - D ko:K06381 - ko00000 Stage II sporulation protein D
EPKEEPDC_01306 4.96e-306 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EPKEEPDC_01307 2.3e-172 ywmB - - S - - - TATA-box binding
EPKEEPDC_01308 4.54e-45 ywzB - - S - - - membrane
EPKEEPDC_01309 7.16e-114 ywmA - - - - - - -
EPKEEPDC_01310 3.89e-72 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
EPKEEPDC_01311 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EPKEEPDC_01312 4.46e-195 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EPKEEPDC_01313 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EPKEEPDC_01314 3.23e-115 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EPKEEPDC_01315 2.62e-79 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EPKEEPDC_01316 3.01e-36 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EPKEEPDC_01317 6.06e-167 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
EPKEEPDC_01318 1.91e-81 atpI - - S ko:K02116 - ko00000,ko00194 ATP synthase
EPKEEPDC_01319 5.5e-148 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EPKEEPDC_01320 1.25e-302 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EPKEEPDC_01321 2.49e-123 ywlG - - S - - - Belongs to the UPF0340 family
EPKEEPDC_01322 2.35e-106 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase
EPKEEPDC_01323 1.58e-100 ywlE 3.1.3.48, 3.9.1.2 - T ko:K01104,ko:K20201 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EPKEEPDC_01324 1.86e-116 mntP - - P - - - Probably functions as a manganese efflux pump
EPKEEPDC_01325 1.22e-249 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
EPKEEPDC_01326 1.79e-100 ywlB - - E - - - Belongs to the acetyltransferase family. ArgA subfamily
EPKEEPDC_01327 3.26e-152 spoIIR - - S ko:K06387 - ko00000 stage II sporulation protein R
EPKEEPDC_01328 9.69e-74 ywlA - - S - - - Uncharacterised protein family (UPF0715)
EPKEEPDC_01330 5.96e-205 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
EPKEEPDC_01331 9.95e-245 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EPKEEPDC_01332 4.84e-89 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EPKEEPDC_01333 8.18e-115 racA - - K ko:K11686 - ko00000,ko03036 Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
EPKEEPDC_01334 3.24e-204 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
EPKEEPDC_01335 0.0 ykwA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
EPKEEPDC_01336 9.96e-135 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
EPKEEPDC_01337 7e-45 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
EPKEEPDC_01338 5.53e-303 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EPKEEPDC_01339 3.51e-225 glpX 3.1.3.11 - G ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 fructose-1,6-bisphosphatase
EPKEEPDC_01340 2.26e-303 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EPKEEPDC_01341 5.69e-147 tal 2.2.1.2 - G ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EPKEEPDC_01342 7.82e-204 fbaA 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Aldolase
EPKEEPDC_01343 1.07e-81 spo0F - - T ko:K02490 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG0784 FOG CheY-like receiver
EPKEEPDC_01344 6.41e-118 ywjG - - S - - - Domain of unknown function (DUF2529)
EPKEEPDC_01345 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
EPKEEPDC_01346 1.03e-82 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
EPKEEPDC_01347 2.98e-269 acdA - - I - - - acyl-CoA dehydrogenase
EPKEEPDC_01348 0.0 ywjF - - C - - - COG0247 Fe-S oxidoreductase
EPKEEPDC_01349 3.43e-262 clsB - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the phospholipase D family. Cardiolipin synthase subfamily
EPKEEPDC_01350 9.45e-234 uvsE - - L ko:K13281 - ko00000,ko01000 Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
EPKEEPDC_01351 1.32e-57 ywjC - - - - - - -
EPKEEPDC_01352 5.49e-124 ywjB - - H - - - RibD C-terminal domain
EPKEEPDC_01353 0.0 ywjA - - V ko:K06147 - ko00000,ko02000 ABC transporter
EPKEEPDC_01354 0.0 ywiE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EPKEEPDC_01355 1.02e-159 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase (gamma
EPKEEPDC_01356 6.53e-121 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase
EPKEEPDC_01357 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase, beta
EPKEEPDC_01358 0.0 narG 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EPKEEPDC_01359 8.67e-111 arfM - - T ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 cyclic nucleotide binding
EPKEEPDC_01360 1.84e-179 ywiC - - S - - - YwiC-like protein
EPKEEPDC_01361 3.27e-168 fnr - - K - - - helix_turn_helix, cAMP Regulatory protein
EPKEEPDC_01362 6.83e-274 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
EPKEEPDC_01363 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
EPKEEPDC_01364 4.64e-96 ywiB - - S - - - protein conserved in bacteria
EPKEEPDC_01365 3.71e-12 - - - S - - - Bacteriocin subtilosin A
EPKEEPDC_01366 0.0 - - - C ko:K22227 - ko00000 Fe-S oxidoreductases
EPKEEPDC_01368 1.5e-169 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
EPKEEPDC_01369 1.64e-101 mgtA 3.6.3.2 - P ko:K01531,ko:K16905 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPase, P-type transporting, HAD superfamily, subfamily IC
EPKEEPDC_01370 1.55e-166 mgtA 3.6.3.2 - P ko:K01531,ko:K16905 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPase, P-type transporting, HAD superfamily, subfamily IC
EPKEEPDC_01371 8.09e-275 - 2.7.1.26, 2.7.7.2 - L ko:K07263,ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01002 Peptidase, M16
EPKEEPDC_01372 2.68e-314 - - - L - - - Peptidase, M16
EPKEEPDC_01374 1.15e-313 ywhL - - CO - - - amine dehydrogenase activity
EPKEEPDC_01375 5.47e-274 ywhK - - CO - - - amine dehydrogenase activity
EPKEEPDC_01376 9.28e-99 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
EPKEEPDC_01379 1.3e-10 - - - - - - - -
EPKEEPDC_01382 1.4e-74 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
EPKEEPDC_01384 2.1e-215 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
EPKEEPDC_01385 1.93e-204 speE 2.5.1.16 - E ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EPKEEPDC_01386 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M ko:K21464 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
EPKEEPDC_01387 1.92e-123 ywhD - - S - - - YwhD family
EPKEEPDC_01388 3.29e-154 ywhC - - S - - - Peptidase family M50
EPKEEPDC_01389 1.43e-35 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 4-oxalocrotonate tautomerase
EPKEEPDC_01390 1.45e-93 ywhA - - K - - - Transcriptional regulator
EPKEEPDC_01391 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EPKEEPDC_01393 1.85e-301 mmr - - U ko:K08166 - ko00000,ko02000 Major Facilitator Superfamily
EPKEEPDC_01394 3.15e-103 yffB - - K - - - Transcriptional regulator
EPKEEPDC_01395 1.47e-115 ywgA - - - ko:K09388 - ko00000 -
EPKEEPDC_01396 0.0 ywfO - - S ko:K06885 - ko00000 COG1078 HD superfamily phosphohydrolases
EPKEEPDC_01397 8.55e-49 ywzC - - S - - - Belongs to the UPF0741 family
EPKEEPDC_01398 5.39e-145 rsfA_1 - - - ko:K06314 - ko00000,ko03000 -
EPKEEPDC_01399 4.32e-202 ywfM - - EG ko:K03298 - ko00000,ko02000 EamA-like transporter family
EPKEEPDC_01400 1.77e-198 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
EPKEEPDC_01401 3.73e-209 cysL - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
EPKEEPDC_01402 1.67e-224 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 In Salmonella this enzyme is required for ethanolamine catabolism
EPKEEPDC_01403 3.43e-187 ywfI - - C ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko01000 May function as heme-dependent peroxidase
EPKEEPDC_01404 3.93e-175 ywfH - - IQ ko:K19550 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Enoyl-(Acyl carrier protein) reductase
EPKEEPDC_01405 2.47e-294 ywfG - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
EPKEEPDC_01406 7.22e-264 bacE - - EGP ko:K19552 - ko00000,ko02000 Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
EPKEEPDC_01407 0.0 bacD 6.3.2.49 - F ko:K13037 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
EPKEEPDC_01408 3.83e-179 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EPKEEPDC_01409 1.24e-175 bacB 5.3.3.19 - S ko:K19547 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
EPKEEPDC_01410 5.11e-146 bacA 4.1.1.100 - E ko:K19546 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
EPKEEPDC_01411 8.95e-274 ywfA - - EGP - - - -transporter
EPKEEPDC_01412 2.65e-316 rocC - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
EPKEEPDC_01413 0.0 rocB - - E - - - arginine degradation protein
EPKEEPDC_01414 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
EPKEEPDC_01415 5.19e-311 rocG 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
EPKEEPDC_01416 6.13e-100 - - - - - - - -
EPKEEPDC_01417 3.73e-113 spsL 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Spore Coat
EPKEEPDC_01418 1.64e-204 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
EPKEEPDC_01419 5.26e-233 spsJ 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
EPKEEPDC_01420 6.13e-177 spsI 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EPKEEPDC_01421 6.69e-239 spsG - - M - - - Spore Coat
EPKEEPDC_01422 5.2e-166 spsF - - M ko:K07257 - ko00000 Spore Coat
EPKEEPDC_01423 6.8e-272 pseI 2.5.1.56, 2.5.1.97 - M ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 acid synthase
EPKEEPDC_01424 1.04e-210 spsD 2.3.1.210 - K ko:K16704 - ko00000,ko01000 Spore Coat
EPKEEPDC_01425 4.54e-285 spsC 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
EPKEEPDC_01426 0.0 spsB - - M - - - Capsule polysaccharide biosynthesis protein
EPKEEPDC_01427 6.64e-186 spsA - - M - - - Spore Coat
EPKEEPDC_01428 3.62e-112 gerQ - - S ko:K06305 - ko00000 Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
EPKEEPDC_01429 1.59e-78 ywdK - - S - - - small membrane protein
EPKEEPDC_01430 1.86e-303 ywdJ - - F - - - Xanthine uracil
EPKEEPDC_01431 2.18e-63 ywdI - - S - - - Family of unknown function (DUF5327)
EPKEEPDC_01432 0.0 ywdH 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
EPKEEPDC_01433 9.47e-166 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EPKEEPDC_01434 4.68e-192 ywdF - - S - - - Glycosyltransferase like family 2
EPKEEPDC_01435 2.21e-187 pdxK 2.7.1.35, 2.7.1.49, 2.7.4.7 - H ko:K00868,ko:K00941 ko00730,ko00750,ko01100,map00730,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
EPKEEPDC_01436 1.07e-39 ywdA - - - - - - -
EPKEEPDC_01437 0.0 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
EPKEEPDC_01438 0.0 sacP 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EPKEEPDC_01439 4.82e-179 - - - P ko:K02598 - ko00000,ko02000 Formate/nitrite transporter
EPKEEPDC_01440 2.6e-193 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
EPKEEPDC_01442 0.0 prtS 3.4.21.110, 3.4.21.96 - O ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
EPKEEPDC_01443 5.71e-237 ywcH - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EPKEEPDC_01444 9.4e-178 nfrA1 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Oxidoreductase
EPKEEPDC_01445 9.57e-241 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
EPKEEPDC_01446 6.61e-52 ywcE - - S - - - Required for proper spore morphogenesis. Important for spore germination
EPKEEPDC_01447 1.12e-83 qoxD 1.10.3.12 - C ko:K02829 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
EPKEEPDC_01448 1.2e-144 qoxC 1.10.3.12 - C ko:K02828 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
EPKEEPDC_01449 0.0 qoxB 1.10.3.12 - C ko:K02827 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EPKEEPDC_01450 6.94e-226 qoxA 1.10.3.12 - C ko:K02826 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
EPKEEPDC_01451 5.11e-49 ydaS - - S - - - membrane
EPKEEPDC_01452 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
EPKEEPDC_01453 4.38e-288 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EPKEEPDC_01454 4.72e-77 gtcA - - S - - - GtrA-like protein
EPKEEPDC_01455 3.42e-158 ywcC - - K - - - transcriptional regulator
EPKEEPDC_01457 2.13e-64 ywcB - - S - - - Protein of unknown function, DUF485
EPKEEPDC_01458 0.0 ywcA - - S ko:K14393 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EPKEEPDC_01459 1.32e-143 ywbO - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
EPKEEPDC_01460 1.47e-306 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Dyp-type peroxidase family protein
EPKEEPDC_01461 1.7e-246 ycdO - - P ko:K07224 - ko00000,ko02000 periplasmic lipoprotein involved in iron transport
EPKEEPDC_01462 0.0 - - - P ko:K07243 - ko00000,ko02000 COG0672 High-affinity Fe2 Pb2 permease
EPKEEPDC_01463 1.43e-145 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
EPKEEPDC_01464 3.25e-185 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EPKEEPDC_01465 2.7e-203 ywbI - - K - - - Transcriptional regulator
EPKEEPDC_01466 1.1e-76 ywbH - - S ko:K06518 - ko00000,ko02000 Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
EPKEEPDC_01467 1.21e-143 ywbG - - M - - - effector of murein hydrolase
EPKEEPDC_01468 1.01e-275 ywbF - - EGP ko:K05820 - ko00000,ko02000 Nucleoside H+ symporter
EPKEEPDC_01469 3.13e-38 ywbE - - S - - - Uncharacterized conserved protein (DUF2196)
EPKEEPDC_01470 1.1e-277 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
EPKEEPDC_01471 1.99e-87 ywbC 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 glyoxalase
EPKEEPDC_01472 8.38e-160 ywbB - - S - - - Protein of unknown function (DUF2711)
EPKEEPDC_01473 1.1e-313 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EPKEEPDC_01474 0.0 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
EPKEEPDC_01475 1.45e-312 sacX 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EPKEEPDC_01476 2.6e-195 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
EPKEEPDC_01477 6.53e-217 gspA - - M - - - General stress
EPKEEPDC_01478 7.35e-160 ywaF - - S - - - Integral membrane protein
EPKEEPDC_01479 3.57e-114 ywaE - - K - - - Transcriptional regulator
EPKEEPDC_01480 7.11e-294 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EPKEEPDC_01481 0.0 ywaD 3.4.11.10, 3.4.11.6 - S ko:K19701 - ko00000,ko01000,ko01002 PA domain
EPKEEPDC_01482 2.52e-149 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 protein conserved in bacteria
EPKEEPDC_01483 4.89e-211 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
EPKEEPDC_01484 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EPKEEPDC_01485 1.14e-297 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 membrane protein involved in D-alanine export
EPKEEPDC_01486 6.83e-50 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EPKEEPDC_01487 4.09e-294 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EPKEEPDC_01488 2.39e-177 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
EPKEEPDC_01489 3.07e-263 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
EPKEEPDC_01490 0.0 licH 3.2.1.86 GT4 G ko:K01222 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
EPKEEPDC_01491 1.58e-50 licA 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EPKEEPDC_01492 0.0 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EPKEEPDC_01493 1.89e-67 licB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 transporter subunit IIB
EPKEEPDC_01494 0.0 licR - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
EPKEEPDC_01495 8.94e-28 yxzF - - - - - - -
EPKEEPDC_01496 3.23e-145 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
EPKEEPDC_01497 0.0 katX 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
EPKEEPDC_01498 3.93e-271 yxlH - - EGP - - - Major Facilitator Superfamily
EPKEEPDC_01499 1.61e-178 yxlG - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
EPKEEPDC_01500 2.75e-98 yxlF - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EPKEEPDC_01501 1.81e-94 yxlF - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EPKEEPDC_01502 1.04e-37 yxlE - - S - - - Phospholipase_D-nuclease N-terminal
EPKEEPDC_01503 1.63e-39 - - - - - - - -
EPKEEPDC_01504 1.3e-60 yxlC - - S - - - Family of unknown function (DUF5345)
EPKEEPDC_01505 2.6e-124 sigY - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
EPKEEPDC_01506 0.0 yxlA - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
EPKEEPDC_01507 1.77e-200 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EPKEEPDC_01508 0.0 cydD - - V ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding protein
EPKEEPDC_01509 0.0 cydC - - V ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding
EPKEEPDC_01510 1.16e-243 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase, subunit II
EPKEEPDC_01511 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
EPKEEPDC_01512 2.67e-308 cimH - - C - - - COG3493 Na citrate symporter
EPKEEPDC_01513 0.0 - - - O - - - Peptidase family M48
EPKEEPDC_01515 5.28e-199 yxkH - - G - - - Polysaccharide deacetylase
EPKEEPDC_01516 3.44e-261 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
EPKEEPDC_01517 4.54e-209 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
EPKEEPDC_01518 0.0 aldY 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
EPKEEPDC_01519 2.29e-188 yxkD - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
EPKEEPDC_01520 4.99e-100 yxkC - - S - - - Domain of unknown function (DUF4352)
EPKEEPDC_01521 6.06e-251 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
EPKEEPDC_01522 2.68e-100 - - - S - - - Protein of unknown function (DUF1453)
EPKEEPDC_01523 6.98e-243 - - - T - - - Signal transduction histidine kinase
EPKEEPDC_01524 1.05e-145 - - - K ko:K02479 - ko00000,ko02022 helix_turn_helix, Lux Regulon
EPKEEPDC_01525 3.16e-298 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
EPKEEPDC_01528 2.88e-111 yxjI - - S - - - LURP-one-related
EPKEEPDC_01529 1.75e-276 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
EPKEEPDC_01530 5.42e-276 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
EPKEEPDC_01531 1.67e-175 yxjF 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
EPKEEPDC_01532 5.91e-151 scoB 2.8.3.5 - I ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
EPKEEPDC_01533 5.43e-167 scoA 2.8.3.5 - I ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EPKEEPDC_01534 5.14e-112 yxjC - - EG - - - COG2610 H gluconate symporter and related permeases
EPKEEPDC_01535 6.4e-172 yxjC - - EG - - - COG2610 H gluconate symporter and related permeases
EPKEEPDC_01536 2.67e-189 yxjB 2.1.1.187 - Q ko:K00563 - ko00000,ko01000,ko03009 Methyltransferase domain
EPKEEPDC_01538 1.72e-268 nupG - - F ko:K16323 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EPKEEPDC_01539 8.1e-131 - - - T - - - Domain of unknown function (DUF4163)
EPKEEPDC_01540 2.28e-63 yxiS - - - - - - -
EPKEEPDC_01541 0.0 katE 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
EPKEEPDC_01542 8.66e-139 citH - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
EPKEEPDC_01543 6.8e-121 citH - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
EPKEEPDC_01544 4.35e-184 bglS - - M - - - licheninase activity
EPKEEPDC_01545 5.66e-193 licT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
EPKEEPDC_01546 2.75e-145 - - - - - - - -
EPKEEPDC_01547 9.34e-293 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 COG2270 Permeases of the major facilitator superfamily
EPKEEPDC_01548 0.0 dbpA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
EPKEEPDC_01549 8.65e-275 - - - E - - - GDSL-like Lipase/Acylhydrolase
EPKEEPDC_01550 4.05e-69 - - - K - - - Transcriptional regulator PadR-like family
EPKEEPDC_01551 7.27e-76 - - - S - - - Protein of unknown function (DUF2812)
EPKEEPDC_01554 7.02e-59 yxiJ - - S - - - YxiJ-like protein
EPKEEPDC_01558 1.83e-43 - - - - - - - -
EPKEEPDC_01559 6.27e-106 yxiI - - S - - - Protein of unknown function (DUF2716)
EPKEEPDC_01560 1.98e-172 - - - - - - - -
EPKEEPDC_01561 8.06e-90 yxiG - - - - - - -
EPKEEPDC_01562 1.48e-47 - - - - - - - -
EPKEEPDC_01564 2.07e-210 yxxF - - EG - - - EamA-like transporter family
EPKEEPDC_01565 6.99e-94 yxiE - - T - - - Belongs to the universal stress protein A family
EPKEEPDC_01566 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
EPKEEPDC_01567 0.0 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EPKEEPDC_01568 2.13e-64 - - - - - - - -
EPKEEPDC_01569 2.4e-80 - - - - - - - -
EPKEEPDC_01570 4.49e-37 - - - - - - - -
EPKEEPDC_01571 1.55e-54 - - - - - - - -
EPKEEPDC_01572 9.35e-74 - - - - - - - -
EPKEEPDC_01573 6.36e-277 - - - S ko:K21493 - ko00000,ko01000,ko02048 nuclease activity
EPKEEPDC_01574 5.43e-52 yxiC - - S - - - Family of unknown function (DUF5344)
EPKEEPDC_01575 1.78e-35 - - - S - - - Domain of unknown function (DUF5082)
EPKEEPDC_01576 0.0 - - - L - - - HKD family nuclease
EPKEEPDC_01577 1.23e-78 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
EPKEEPDC_01578 2.2e-193 - - - L - - - Protein of unknown function (DUF2726)
EPKEEPDC_01579 0.0 yxiA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
EPKEEPDC_01580 7.02e-103 hutP - - K ko:K09683 - ko00000,ko03000 Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
EPKEEPDC_01581 0.0 hutH 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Histidine ammonia-lyase
EPKEEPDC_01582 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EPKEEPDC_01583 7.47e-298 hutI 3.5.2.7 - Q ko:K01468 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Imidazolone-5-propionate hydrolase
EPKEEPDC_01584 2.58e-226 hutG 3.5.3.8 - E ko:K01479 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
EPKEEPDC_01585 0.0 ybgF - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
EPKEEPDC_01586 8.11e-299 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
EPKEEPDC_01587 2.72e-263 nupC - - F ko:K11535 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EPKEEPDC_01588 8.3e-150 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EPKEEPDC_01589 1.22e-221 deoR - - K ko:K05346 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
EPKEEPDC_01590 1.51e-196 - - - S - - - Domain of Unknown Function (DUF1206)
EPKEEPDC_01591 1.05e-253 eutH - - E ko:K04023 - ko00000 Ethanolamine utilisation protein, EutH
EPKEEPDC_01592 2.69e-310 yxeQ - - S - - - MmgE/PrpD family
EPKEEPDC_01593 9.65e-271 yxeP - - E ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
EPKEEPDC_01594 9.69e-171 yxeO - - P ko:K16960,ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
EPKEEPDC_01595 3e-148 yxeN - - P ko:K10009,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
EPKEEPDC_01596 4.3e-186 yxeM - - M ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
EPKEEPDC_01597 5.16e-120 yxeL - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EPKEEPDC_01598 0.0 yxeK - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EPKEEPDC_01600 2.24e-236 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
EPKEEPDC_01601 2.71e-192 yxeH - - S - - - hydrolases of the HAD superfamily
EPKEEPDC_01604 7.32e-42 yxeE - - - - - - -
EPKEEPDC_01605 7.57e-28 yxeD - - - - - - -
EPKEEPDC_01606 3.93e-90 - - - - - - - -
EPKEEPDC_01607 1.43e-224 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
EPKEEPDC_01608 1.41e-75 yxeA - - S - - - Protein of unknown function (DUF1093)
EPKEEPDC_01609 0.0 yxdM - - V ko:K11636 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
EPKEEPDC_01610 5.21e-179 yxdL - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
EPKEEPDC_01611 3.67e-229 yxdK 2.7.13.3 - T ko:K11633 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EPKEEPDC_01612 2.8e-160 yxdJ - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EPKEEPDC_01613 2.83e-204 fbaA 4.1.2.13, 4.1.2.29 - F ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
EPKEEPDC_01614 2.19e-186 iolI 5.3.99.11 - G ko:K06606 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
EPKEEPDC_01615 1.08e-212 iolH - - G ko:K06605 - ko00000 Xylose isomerase-like TIM barrel
EPKEEPDC_01616 1.55e-251 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
EPKEEPDC_01617 8.46e-298 iolF - - EGP ko:K06610 - ko00000,ko02000 Major facilitator superfamily
EPKEEPDC_01618 8.63e-223 iolE 4.2.1.44 - G ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
EPKEEPDC_01619 0.0 iolD 3.7.1.22 - E ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
EPKEEPDC_01620 1.01e-226 iolC 2.7.1.92 - G ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
EPKEEPDC_01621 1.41e-199 iolB 5.3.1.30 - G ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
EPKEEPDC_01622 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
EPKEEPDC_01623 1.56e-177 iolR - - K ko:K06608,ko:K11534 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
EPKEEPDC_01624 1.74e-224 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
EPKEEPDC_01626 2.04e-64 yxcD - - S - - - Protein of unknown function (DUF2653)
EPKEEPDC_01628 5.72e-117 - - - S - - - CGNR zinc finger
EPKEEPDC_01629 9.41e-105 - - - T - - - HPP family
EPKEEPDC_01630 2.8e-311 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
EPKEEPDC_01631 0.0 htpG - - O ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Molecular chaperone. Has ATPase activity
EPKEEPDC_01633 1.14e-190 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
EPKEEPDC_01634 2.84e-263 yxbF - - K - - - Bacterial regulatory proteins, tetR family
EPKEEPDC_01635 2.8e-312 aldX 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
EPKEEPDC_01636 3.89e-30 yxaI - - S - - - membrane protein domain
EPKEEPDC_01637 7.49e-137 yxaL - - S - - - PQQ-like domain
EPKEEPDC_01638 8.92e-80 - - - S - - - Family of unknown function (DUF5391)
EPKEEPDC_01639 4.03e-99 yxaI - - S - - - membrane protein domain
EPKEEPDC_01640 5.11e-284 - - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
EPKEEPDC_01641 6.05e-250 - 1.13.11.24 - S ko:K07155 - ko00000,ko01000 AraC-like ligand binding domain
EPKEEPDC_01642 3.22e-129 yxaF - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
EPKEEPDC_01643 1.23e-254 yxnA - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
EPKEEPDC_01644 6.83e-94 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
EPKEEPDC_01645 5.1e-78 - - - S ko:K06518 - ko00000,ko02000 LrgA family
EPKEEPDC_01646 1.27e-152 yxaC - - M - - - effector of murein hydrolase
EPKEEPDC_01647 3.62e-245 - - - GM ko:K19426 - ko00000,ko01000 Polysaccharide pyruvyl transferase
EPKEEPDC_01648 1.35e-262 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
EPKEEPDC_01649 3.63e-163 gntR - - K ko:K11476 - ko00000,ko03000 transcriptional
EPKEEPDC_01650 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
EPKEEPDC_01651 1.18e-294 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
EPKEEPDC_01652 0.0 gntZ 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EPKEEPDC_01653 9.33e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Alkyl hydroperoxide reductase
EPKEEPDC_01654 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 Alkyl hydroperoxide reductase
EPKEEPDC_01655 1.58e-237 - - - S - - - Polysaccharide pyruvyl transferase
EPKEEPDC_01656 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
EPKEEPDC_01657 9.18e-23 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EPKEEPDC_01658 3.94e-159 yydK - - K ko:K03489 - ko00000,ko03000 Transcriptional regulator
EPKEEPDC_01659 3.04e-24 - - - - - - - -
EPKEEPDC_01660 5.49e-152 - - - S ko:K16916 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
EPKEEPDC_01661 8.4e-143 - - - P ko:K16917 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
EPKEEPDC_01662 3.65e-172 - - - O ko:K16922 - ko00000,ko01002 Peptidase M50
EPKEEPDC_01663 2.24e-236 - - - S - - - Radical SAM superfamily
EPKEEPDC_01664 8.12e-17 - - - - - - - -
EPKEEPDC_01665 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Firmicute fructose-1,6-bisphosphatase
EPKEEPDC_01667 5e-106 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EPKEEPDC_01669 3.72e-86 - - - - - - - -
EPKEEPDC_01670 1.81e-297 yycR 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
EPKEEPDC_01672 1.3e-40 yycQ - - S - - - Protein of unknown function (DUF2651)
EPKEEPDC_01673 5.57e-269 yycP - - - - - - -
EPKEEPDC_01674 1.32e-166 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
EPKEEPDC_01675 4.32e-110 yycN - - K - - - Acetyltransferase
EPKEEPDC_01676 1.23e-238 - - - S - - - aspartate phosphatase
EPKEEPDC_01678 3.22e-213 rocF 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
EPKEEPDC_01679 0.0 rocE - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
EPKEEPDC_01680 3.38e-293 rocD 2.6.1.13 - E ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko01007 Catalyzes the interconversion of ornithine to glutamate semialdehyde
EPKEEPDC_01681 0.0 rocR - - KT ko:K06714 - ko00000,ko03000 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
EPKEEPDC_01682 5.45e-278 yyxA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EPKEEPDC_01683 1.15e-190 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
EPKEEPDC_01684 1.2e-200 yycI - - S - - - protein conserved in bacteria
EPKEEPDC_01685 0.0 yycH - - S - - - protein conserved in bacteria
EPKEEPDC_01686 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EPKEEPDC_01687 1.45e-172 yycF - - T ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EPKEEPDC_01692 1.29e-314 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EPKEEPDC_01693 1.02e-71 yycE - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EPKEEPDC_01694 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
EPKEEPDC_01695 3.48e-40 yycD - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
EPKEEPDC_01697 1.89e-22 yycC - - K - - - YycC-like protein
EPKEEPDC_01698 4.19e-283 yycB - - P ko:K03449 - ko00000,ko02000 COG2807 Cyanate permease
EPKEEPDC_01699 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EPKEEPDC_01700 2.74e-96 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
EPKEEPDC_01701 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
EPKEEPDC_01702 5.23e-205 yybS - - S - - - membrane
EPKEEPDC_01704 2.89e-110 cotF - - M ko:K06329 - ko00000 Spore coat protein
EPKEEPDC_01705 6.68e-90 yybR - - K - - - Transcriptional regulator
EPKEEPDC_01706 4.89e-210 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
EPKEEPDC_01707 7.84e-91 - - - - - - - -
EPKEEPDC_01709 1.01e-307 yybO - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
EPKEEPDC_01710 5.74e-34 - - - K - - - TipAS antibiotic-recognition domain
EPKEEPDC_01711 7.9e-73 - - - K - - - TipAS antibiotic-recognition domain
EPKEEPDC_01712 3.96e-181 - - - - - - - -
EPKEEPDC_01713 5.02e-87 - - - S - - - SnoaL-like domain
EPKEEPDC_01714 2.16e-164 - - - S - - - Metallo-beta-lactamase superfamily
EPKEEPDC_01715 4.54e-100 yybA - - K - - - transcriptional
EPKEEPDC_01716 1.16e-92 yjcF - - S - - - Acetyltransferase (GNAT) domain
EPKEEPDC_01717 4.28e-125 yyaS - - S ko:K07149 - ko00000 Membrane
EPKEEPDC_01718 1.91e-119 - - - K ko:K19273 - ko00000,ko01000,ko01504 Acetyltransferase (GNAT) domain
EPKEEPDC_01719 7.41e-86 - - - S - - - YjbR
EPKEEPDC_01720 6.31e-139 yyaP - - H - - - RibD C-terminal domain
EPKEEPDC_01721 1.29e-18 yddB - - S - - - Conjugative transposon protein TcpC
EPKEEPDC_01724 1.3e-58 yddA - - - - - - -
EPKEEPDC_01729 0.0 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
EPKEEPDC_01730 6.73e-212 yyaK - - S ko:K07052 - ko00000 CAAX protease self-immunity
EPKEEPDC_01731 0.0 - - - EGP ko:K08369 - ko00000,ko02000 Major facilitator superfamily
EPKEEPDC_01732 1.33e-129 vatD 2.3.1.28, 2.3.1.79 - S ko:K00638,ko:K00661,ko:K18234 - br01600,ko00000,ko01000,ko01504 Bacterial transferase hexapeptide (six repeats)
EPKEEPDC_01733 1.2e-88 yyaH 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EPKEEPDC_01734 1.61e-225 ccpB - - K - - - Transcriptional regulator
EPKEEPDC_01735 2.07e-187 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
EPKEEPDC_01736 4.25e-49 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EPKEEPDC_01737 1.81e-103 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
EPKEEPDC_01738 1.01e-61 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
EPKEEPDC_01739 5.65e-256 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
EPKEEPDC_01740 0.0 yyaE - - C - - - Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EPKEEPDC_01741 7.41e-45 yyzM - - S - - - protein conserved in bacteria
EPKEEPDC_01742 2.17e-226 yyaD - - S - - - Membrane
EPKEEPDC_01743 4.53e-145 yyaC - - S - - - Sporulation protein YyaC
EPKEEPDC_01744 3.96e-191 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
EPKEEPDC_01745 4.79e-173 soj - - D ko:K03496 - ko00000,ko03036,ko04812 COG1192 ATPases involved in chromosome partitioning
EPKEEPDC_01746 9.26e-98 - - - S - - - Bacterial PH domain
EPKEEPDC_01747 9e-193 noc - - D ko:K03497 - ko00000,ko03000,ko03036,ko04812 Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
EPKEEPDC_01748 1.01e-167 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
EPKEEPDC_01749 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
EPKEEPDC_01750 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EPKEEPDC_01751 1.83e-141 jag - - S ko:K06346 - ko00000 single-stranded nucleic acid binding R3H
EPKEEPDC_01752 9.29e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EPKEEPDC_01753 8.1e-71 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
EPKEEPDC_01754 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EPKEEPDC_01755 1.71e-263 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
EPKEEPDC_01756 2.24e-45 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
EPKEEPDC_01757 1.85e-263 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EPKEEPDC_01758 1.25e-51 yaaB - - S - - - Domain of unknown function (DUF370)
EPKEEPDC_01759 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EPKEEPDC_01760 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EPKEEPDC_01761 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
EPKEEPDC_01764 4.14e-230 yaaC - - S - - - YaaC-like Protein
EPKEEPDC_01765 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
EPKEEPDC_01766 3.75e-316 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
EPKEEPDC_01767 3.7e-202 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
EPKEEPDC_01768 3.34e-138 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
EPKEEPDC_01769 3.5e-289 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EPKEEPDC_01771 3.72e-159 dck 2.7.1.74, 2.7.1.76 - F ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko01000 Deoxycytidine kinase
EPKEEPDC_01772 5.73e-149 dgk 2.7.1.113 - F ko:K15518 ko00230,map00230 ko00000,ko00001,ko01000 Deoxyguanosine kinase
EPKEEPDC_01773 1.48e-275 yaaH - - M ko:K06306 - ko00000 Glycoside Hydrolase Family
EPKEEPDC_01774 3.26e-124 yaaI - - Q - - - COG1335 Amidases related to nicotinamidase
EPKEEPDC_01775 2.47e-107 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
EPKEEPDC_01776 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EPKEEPDC_01777 8.75e-55 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EPKEEPDC_01778 8.53e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EPKEEPDC_01779 1.55e-42 yaaL - - S - - - Protein of unknown function (DUF2508)
EPKEEPDC_01780 1.25e-47 bofA - - S ko:K06317 - ko00000 Sigma-K factor-processing regulatory protein BofA
EPKEEPDC_01781 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
EPKEEPDC_01784 2.21e-42 csfB - - S - - - Inhibitor of sigma-G Gin
EPKEEPDC_01785 3.83e-132 xpaC - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
EPKEEPDC_01786 1.69e-258 yaaN - - P - - - Belongs to the TelA family
EPKEEPDC_01787 0.0 yaaO - - E - - - Orn Lys Arg decarboxylase
EPKEEPDC_01788 4.67e-146 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EPKEEPDC_01789 1.02e-72 yaaQ - - S - - - protein conserved in bacteria
EPKEEPDC_01790 1.26e-95 yaaR - - S ko:K09770 - ko00000 protein conserved in bacteria
EPKEEPDC_01791 2.82e-235 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
EPKEEPDC_01792 6.33e-189 yaaT - - S - - - stage 0 sporulation protein
EPKEEPDC_01793 1.53e-56 yabA - - L - - - Involved in initiation control of chromosome replication
EPKEEPDC_01794 1.63e-177 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Conserved hypothetical protein 95
EPKEEPDC_01795 1.2e-64 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
EPKEEPDC_01796 2.95e-207 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EPKEEPDC_01797 1.51e-58 abrB - - K ko:K06284 - ko00000,ko03000 COG2002 Regulators of stationary sporulation gene expression
EPKEEPDC_01798 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EPKEEPDC_01799 5.9e-184 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD
EPKEEPDC_01800 4.1e-278 yabE - - T - - - protein conserved in bacteria
EPKEEPDC_01801 1.43e-125 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EPKEEPDC_01802 1.44e-198 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
EPKEEPDC_01803 1.11e-198 yabG - - S ko:K06436 - ko00000 peptidase
EPKEEPDC_01804 5.32e-53 veg - - S - - - protein conserved in bacteria
EPKEEPDC_01805 3.96e-37 sspF - - S ko:K06423 - ko00000 DNA topological change
EPKEEPDC_01806 2.34e-207 ispE 2.7.1.148 - I ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EPKEEPDC_01807 4.66e-196 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
EPKEEPDC_01808 3.45e-83 yabJ 3.5.99.10 - J ko:K09022 - ko00000,ko01000 translation initiation inhibitor, yjgF family
EPKEEPDC_01809 2.45e-63 spoVG - - D ko:K06412 - ko00000 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
EPKEEPDC_01811 2.58e-309 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EPKEEPDC_01812 1.22e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EPKEEPDC_01813 1.45e-136 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EPKEEPDC_01814 8.28e-135 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
EPKEEPDC_01815 5.24e-53 yabK - - S - - - Peptide ABC transporter permease
EPKEEPDC_01816 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EPKEEPDC_01817 5.88e-121 spoVT - - K ko:K04769 - ko00000,ko03000 stage V sporulation protein
EPKEEPDC_01818 0.0 yabM - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EPKEEPDC_01819 0.0 yabN 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
EPKEEPDC_01820 4.22e-50 yabO - - J - - - COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
EPKEEPDC_01821 1.91e-66 yabP - - S - - - Sporulation protein YabP
EPKEEPDC_01822 1.49e-137 yabQ - - S - - - spore cortex biosynthesis protein
EPKEEPDC_01823 1.2e-74 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
EPKEEPDC_01824 2.49e-82 yabR - - J ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
EPKEEPDC_01827 0.0 spoIIE 3.1.3.16 - KT ko:K06382 - ko00000,ko01000 stage II sporulation protein E
EPKEEPDC_01828 5.61e-168 yabS - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
EPKEEPDC_01829 2.47e-220 yabT 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 serine threonine protein kinase
EPKEEPDC_01830 0.0 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
EPKEEPDC_01831 4.82e-121 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
EPKEEPDC_01832 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EPKEEPDC_01833 6.92e-189 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EPKEEPDC_01834 9.54e-208 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EPKEEPDC_01835 8.93e-172 yacD 5.2.1.8 - O ko:K07533 - ko00000,ko01000,ko03110 peptidyl-prolyl isomerase
EPKEEPDC_01836 1.54e-217 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
EPKEEPDC_01837 0.0 pabB 2.6.1.85 - EH ko:K01665 ko00790,map00790 ko00000,ko00001,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EPKEEPDC_01838 2.44e-136 pabA 2.6.1.85 - EH ko:K01664 ko00790,map00790 ko00000,ko00001,ko01000 Anthranilate synthase
EPKEEPDC_01839 1.08e-214 pabC 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 4-amino-4-deoxychorismate lyase
EPKEEPDC_01840 3.88e-204 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EPKEEPDC_01841 3.8e-80 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EPKEEPDC_01842 4.56e-115 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EPKEEPDC_01843 1.81e-41 yazB - - K - - - transcriptional
EPKEEPDC_01844 7.56e-242 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EPKEEPDC_01845 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
EPKEEPDC_01846 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
EPKEEPDC_01856 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
EPKEEPDC_01857 8.72e-100 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
EPKEEPDC_01858 2.36e-74 mcsA - - S ko:K19411 - ko00000 protein with conserved CXXC pairs
EPKEEPDC_01859 7.74e-257 mcsB 2.7.14.1 - E ko:K19405 - ko00000,ko01000 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
EPKEEPDC_01860 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
EPKEEPDC_01861 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EPKEEPDC_01862 3.8e-251 disA 2.7.7.85 - L ko:K07067 - ko00000,ko01000 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
EPKEEPDC_01863 2.57e-252 yacL - - S - - - COG4956 Integral membrane protein (PIN domain superfamily)
EPKEEPDC_01864 1.82e-162 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
EPKEEPDC_01865 2.59e-112 ispF 2.7.7.60, 4.6.1.12 - I ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
EPKEEPDC_01866 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EPKEEPDC_01867 1.91e-152 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Serine acetyltransferase
EPKEEPDC_01868 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
EPKEEPDC_01869 2.04e-95 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EPKEEPDC_01870 3.52e-173 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EPKEEPDC_01871 3.31e-114 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
EPKEEPDC_01872 3.27e-149 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
EPKEEPDC_01873 2.65e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
EPKEEPDC_01874 1.37e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
EPKEEPDC_01875 3.4e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EPKEEPDC_01876 1.82e-162 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
EPKEEPDC_01877 4.03e-104 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EPKEEPDC_01878 2.84e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
EPKEEPDC_01879 5.1e-140 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
EPKEEPDC_01880 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EPKEEPDC_01881 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EPKEEPDC_01882 1.99e-44 rplGB - - J ko:K07590 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the eukaryotic ribosomal protein eL8 family
EPKEEPDC_01883 6.67e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EPKEEPDC_01884 4.85e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
EPKEEPDC_01885 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EPKEEPDC_01886 2.01e-287 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EPKEEPDC_01887 9.05e-231 ybaC - - S - - - Alpha/beta hydrolase family
EPKEEPDC_01888 2.58e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
EPKEEPDC_01889 7.2e-144 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EPKEEPDC_01890 7.98e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
EPKEEPDC_01891 3.27e-58 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
EPKEEPDC_01892 2.72e-200 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EPKEEPDC_01893 2.83e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EPKEEPDC_01894 9.23e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EPKEEPDC_01895 1.69e-151 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EPKEEPDC_01896 1.96e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EPKEEPDC_01897 1.88e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
EPKEEPDC_01898 1.64e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EPKEEPDC_01899 3.62e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EPKEEPDC_01900 1.43e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EPKEEPDC_01901 7.72e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EPKEEPDC_01902 1.43e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EPKEEPDC_01903 3.11e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EPKEEPDC_01904 4.47e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EPKEEPDC_01905 2.89e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EPKEEPDC_01906 9.16e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EPKEEPDC_01907 1.59e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
EPKEEPDC_01908 7.32e-95 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
EPKEEPDC_01909 5.7e-298 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
EPKEEPDC_01910 2.51e-157 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
EPKEEPDC_01911 2.32e-182 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
EPKEEPDC_01912 2.92e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EPKEEPDC_01913 2.45e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
EPKEEPDC_01914 1.09e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EPKEEPDC_01915 3.24e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EPKEEPDC_01916 7.01e-217 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EPKEEPDC_01917 4.27e-77 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
EPKEEPDC_01918 7.5e-200 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EPKEEPDC_01919 4.47e-196 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EPKEEPDC_01920 1.6e-177 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EPKEEPDC_01921 1.24e-181 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
EPKEEPDC_01922 1.13e-102 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EPKEEPDC_01923 4.28e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
EPKEEPDC_01924 2.06e-184 ybaJ - - Q - - - Methyltransferase domain
EPKEEPDC_01925 2.54e-91 ybaK - - S - - - Protein of unknown function (DUF2521)
EPKEEPDC_01926 9.05e-170 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
EPKEEPDC_01927 1.1e-255 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
EPKEEPDC_01928 1.04e-122 gerD - - - ko:K06294 - ko00000 -
EPKEEPDC_01929 5.95e-133 kbaA - - S ko:K06349 - ko00000 Involved in the activation of the KinB signaling pathway of sporulation
EPKEEPDC_01930 2.49e-180 pdaB - - G - - - Polysaccharide deacetylase
EPKEEPDC_01931 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
EPKEEPDC_01938 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
EPKEEPDC_01939 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
EPKEEPDC_01940 0.0 ybaR - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
EPKEEPDC_01941 1.47e-200 ybaS - - S - - - Na -dependent transporter
EPKEEPDC_01942 1.33e-173 ybbA - - S ko:K07017 - ko00000 Putative esterase
EPKEEPDC_01943 1.01e-227 feuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EPKEEPDC_01944 2.88e-226 feuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EPKEEPDC_01945 5.12e-216 feuA - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Iron-uptake system-binding protein
EPKEEPDC_01946 0.0 ybbB - - K ko:K21701 - ko00000,ko03000 COG2207 AraC-type DNA-binding domain-containing proteins
EPKEEPDC_01947 2.33e-302 ybbC - - S - - - protein conserved in bacteria
EPKEEPDC_01948 0.0 ybbD 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
EPKEEPDC_01949 0.0 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the UPF0214 family
EPKEEPDC_01950 2.97e-303 ybbF 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EPKEEPDC_01951 5.43e-194 ybbH - - K - - - transcriptional
EPKEEPDC_01952 5.5e-209 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EPKEEPDC_01953 3.13e-114 ybbJ - - J - - - acetyltransferase
EPKEEPDC_01954 2.43e-100 ybbK - - S - - - Protein of unknown function (DUF523)
EPKEEPDC_01960 4.59e-127 sigW - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
EPKEEPDC_01961 2.73e-152 rsiW - - K - - - Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
EPKEEPDC_01962 5.43e-189 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EPKEEPDC_01963 3.55e-291 ybbR - - S - - - protein conserved in bacteria
EPKEEPDC_01964 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EPKEEPDC_01965 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
EPKEEPDC_01966 3.95e-222 alkA 3.2.2.21 - L ko:K01247,ko:K13529 ko03410,map03410 ko00000,ko00001,ko01000,ko03000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EPKEEPDC_01967 1.78e-152 adaA - - K ko:K13530 - ko00000,ko01000,ko03000,ko03400 Transcriptional regulator
EPKEEPDC_01968 1.06e-126 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EPKEEPDC_01969 0.0 ndhF 1.6.5.3 - CP ko:K05577 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
EPKEEPDC_01970 0.0 ybcC - - S ko:K09822 - ko00000 Belongs to the UPF0753 family
EPKEEPDC_01971 1.83e-118 ybcF - - P - - - carbonic anhydrase
EPKEEPDC_01972 1.6e-63 - - - - - - - -
EPKEEPDC_01973 3.6e-80 ybcI - - S - - - Uncharacterized conserved protein (DUF2294)
EPKEEPDC_01974 9.45e-67 - - - K - - - Helix-turn-helix domain
EPKEEPDC_01975 1.27e-255 ybcL - - EGP ko:K08164 - ko00000,ko02000 COG2814 Arabinose efflux permease
EPKEEPDC_01976 3.35e-73 - - - - - - - -
EPKEEPDC_01977 6.35e-230 - - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
EPKEEPDC_01978 6.9e-158 - - - T ko:K02483 - ko00000,ko02022 Transcriptional regulatory protein, C terminal
EPKEEPDC_01979 1.08e-216 - - - T - - - His Kinase A (phospho-acceptor) domain
EPKEEPDC_01981 9.33e-177 ybdM 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 Protein tyrosine kinase
EPKEEPDC_01982 9e-194 ybdN - - - - - - -
EPKEEPDC_01983 1.42e-270 ybdO - - S - - - Domain of unknown function (DUF4885)
EPKEEPDC_01984 0.0 ybxG - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
EPKEEPDC_01985 5.46e-51 csgA - - S - - - Sigma-G-dependent sporulation-specific SASP protein
EPKEEPDC_01986 6.92e-41 ybxH - - S - - - Family of unknown function (DUF5370)
EPKEEPDC_01987 7.18e-191 ybxI 3.5.2.6 - V ko:K17838 ko01501,map01501 ko00000,ko00001,ko01000 beta-lactamase
EPKEEPDC_01988 3.8e-314 cypC 1.11.2.4 - Q ko:K15629 - ko00000,ko00199,ko01000 Cytochrome P450
EPKEEPDC_01989 1.11e-54 ybyB - - - - - - -
EPKEEPDC_01990 0.0 ybeC - - E - - - amino acid
EPKEEPDC_01991 5.52e-208 glpQ 3.1.3.1, 3.1.4.46 - C ko:K01113,ko:K01126 ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 glycerophosphoryl diester phosphodiesterase
EPKEEPDC_01992 0.0 glpT - - G ko:K02445 - ko00000,ko02000 -transporter
EPKEEPDC_01993 1.02e-46 - - - S - - - Protein of unknown function (DUF2651)
EPKEEPDC_01994 1e-216 ybfA - - K - - - FR47-like protein
EPKEEPDC_01995 9.18e-285 ybfB - - G - - - COG0477 Permeases of the major facilitator superfamily
EPKEEPDC_01997 0.0 ybfG - - M - - - Domain of unknown function (DUF1906)
EPKEEPDC_01998 6.15e-207 ybfH - - EG - - - EamA-like transporter family
EPKEEPDC_01999 7.39e-188 ybfI - - K - - - AraC-like ligand binding domain
EPKEEPDC_02000 7.62e-270 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EPKEEPDC_02001 2.39e-228 mpr - - M - - - Belongs to the peptidase S1B family
EPKEEPDC_02003 1.41e-211 - - - S - - - Alpha/beta hydrolase family
EPKEEPDC_02004 2.81e-123 pssA 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EPKEEPDC_02005 7.07e-112 ybfM - - S - - - SNARE associated Golgi protein
EPKEEPDC_02006 2.06e-188 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
EPKEEPDC_02007 1.58e-59 ybfN - - - - - - -
EPKEEPDC_02008 0.0 - - - S ko:K06880 - ko00000,ko01000,ko01504 Erythromycin esterase
EPKEEPDC_02009 1.16e-244 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
EPKEEPDC_02010 4.25e-273 gltP - - C ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
EPKEEPDC_02011 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EPKEEPDC_02012 3.02e-174 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
EPKEEPDC_02013 2.91e-165 - - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
EPKEEPDC_02015 1.46e-257 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
EPKEEPDC_02016 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
EPKEEPDC_02017 4.32e-232 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine
EPKEEPDC_02018 0.0 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
EPKEEPDC_02019 3.06e-238 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
EPKEEPDC_02020 5.88e-293 glnJ 2.7.13.3 - T ko:K07717 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EPKEEPDC_02021 5.76e-216 glnL - - T ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Regulator
EPKEEPDC_02022 4.1e-222 ycbC 4.2.1.41 - EM ko:K01707 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 5-dehydro-4-deoxyglucarate dehydratase activity
EPKEEPDC_02023 0.0 ycbD - - C ko:K22187 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
EPKEEPDC_02024 0.0 gudP - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
EPKEEPDC_02025 0.0 gudD 4.2.1.40 - M ko:K01706 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
EPKEEPDC_02026 2.3e-161 ycbG - - K ko:K05799 - ko00000,ko03000 FCD
EPKEEPDC_02027 0.0 garD 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
EPKEEPDC_02028 1.43e-221 ycbJ - - S ko:K06979 - br01600,ko00000,ko00002,ko01504 Macrolide 2'-phosphotransferase
EPKEEPDC_02029 8.73e-33 rtpA - - K - - - Tryptophan RNA-binding attenuator protein inhibitory protein
EPKEEPDC_02030 6.77e-177 eamA1 - - EG - - - spore germination
EPKEEPDC_02031 2.61e-160 ycbL - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EPKEEPDC_02032 2.26e-216 ycbM - - T - - - Histidine kinase
EPKEEPDC_02033 3.74e-213 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EPKEEPDC_02034 2.87e-148 - - - S - - - ABC-2 family transporter protein
EPKEEPDC_02035 2.21e-76 ycbP - - S - - - Protein of unknown function (DUF2512)
EPKEEPDC_02036 5.22e-102 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
EPKEEPDC_02037 2.7e-174 ycbR - - T - - - vWA found in TerF C terminus
EPKEEPDC_02038 0.0 phoD 3.1.3.1 - P ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG3540 Phosphodiesterase alkaline phosphatase D
EPKEEPDC_02039 3.12e-38 tatAD - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
EPKEEPDC_02040 3.09e-159 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EPKEEPDC_02041 8.43e-155 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EPKEEPDC_02042 1.45e-260 ycbU - - E - - - Selenocysteine lyase
EPKEEPDC_02043 1.24e-302 lmrB - - EGP ko:K18926 - ko00000,ko00002,ko02000 the major facilitator superfamily
EPKEEPDC_02044 6.54e-132 lmrA - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
EPKEEPDC_02045 1.14e-255 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
EPKEEPDC_02046 1.63e-146 - 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
EPKEEPDC_02047 2.31e-73 - - - S - - - RDD family
EPKEEPDC_02048 1.18e-253 yccF - - K ko:K07039 - ko00000 SEC-C motif
EPKEEPDC_02049 8.04e-209 natK 2.7.13.3 - T ko:K11640 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
EPKEEPDC_02050 2.79e-162 natR - - T ko:K02477,ko:K11641 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
EPKEEPDC_02051 2.2e-170 natA 3.6.3.7 - CP ko:K01990,ko:K09697 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
EPKEEPDC_02052 1.27e-253 - - - CP ko:K09696 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
EPKEEPDC_02053 5.59e-221 yccK - - C - - - Aldo keto reductase
EPKEEPDC_02054 1.35e-241 ycdA - - S - - - Domain of unknown function (DUF5105)
EPKEEPDC_02055 0.0 ycdB - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
EPKEEPDC_02056 0.0 ycdC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
EPKEEPDC_02057 2.98e-120 - - - M ko:K17733 - ko00000,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
EPKEEPDC_02058 2.86e-248 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
EPKEEPDC_02059 5.63e-179 - 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
EPKEEPDC_02060 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
EPKEEPDC_02061 1.95e-221 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
EPKEEPDC_02062 2.32e-169 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
EPKEEPDC_02063 4.63e-173 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
EPKEEPDC_02064 2.83e-236 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EPKEEPDC_02065 2.64e-141 yceC 3.5.4.33 - T ko:K11991 - ko00000,ko01000,ko03016 proteins involved in stress response, homologs of TerZ and
EPKEEPDC_02066 8.9e-137 yceD - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
EPKEEPDC_02067 4.97e-138 yceE - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
EPKEEPDC_02068 1.18e-175 yceF - - P ko:K05794 - ko00000 Protein of unknown function (DUF475)
EPKEEPDC_02069 0.0 yceG - - S - - - Putative component of 'biosynthetic module'
EPKEEPDC_02070 4.21e-245 yceH - - P - - - Belongs to the TelA family
EPKEEPDC_02071 1.56e-277 yceI - - P ko:K08369 - ko00000,ko02000 Uncharacterised MFS-type transporter YbfB
EPKEEPDC_02072 2.68e-257 - - - EGP - - - Uncharacterised MFS-type transporter YbfB
EPKEEPDC_02073 4.82e-61 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
EPKEEPDC_02074 8.99e-293 opuAA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
EPKEEPDC_02075 2.1e-186 opuAB - - P ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
EPKEEPDC_02076 2.01e-210 opuAC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
EPKEEPDC_02077 1.55e-273 amhX - - S ko:K14665 - ko00000,ko01000,ko01002 amidohydrolase
EPKEEPDC_02078 0.0 ycgA - - S - - - Membrane
EPKEEPDC_02079 3.86e-105 ycgB - - - - - - -
EPKEEPDC_02080 0.0 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
EPKEEPDC_02081 2.06e-233 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
EPKEEPDC_02082 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
EPKEEPDC_02083 0.0 mdr - - EGP - - - the major facilitator superfamily
EPKEEPDC_02084 3.7e-101 ycgE - - K - - - helix_turn_helix multiple antibiotic resistance protein
EPKEEPDC_02085 1.84e-146 ycgF - - E - - - Lysine exporter protein LysE YggA
EPKEEPDC_02086 2.16e-194 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
EPKEEPDC_02087 0.0 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
EPKEEPDC_02088 7.6e-145 ycgI - - S ko:K09967 - ko00000 Domain of unknown function (DUF1989)
EPKEEPDC_02089 3.69e-191 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
EPKEEPDC_02090 3.09e-139 tmrB - - S - - - AAA domain
EPKEEPDC_02092 1.05e-136 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EPKEEPDC_02093 5.27e-186 - - - Q - - - ubiE/COQ5 methyltransferase family
EPKEEPDC_02094 2.67e-224 ycgK - - K ko:K04761 ko02026,map02026 ko00000,ko00001,ko03000 LysR substrate binding domain
EPKEEPDC_02095 1.29e-230 cah 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 Acetyl xylan esterase (AXE1)
EPKEEPDC_02096 2.22e-186 ycgL - - S ko:K07074 - ko00000 Predicted nucleotidyltransferase
EPKEEPDC_02097 3.63e-218 ycgM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
EPKEEPDC_02098 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
EPKEEPDC_02099 2.64e-316 putP - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EPKEEPDC_02100 3.92e-288 ycgP - - QT - - - COG2508 Regulator of polyketide synthase expression
EPKEEPDC_02101 3.82e-195 ycgQ - - S ko:K08986 - ko00000 membrane
EPKEEPDC_02102 3.19e-187 ycgR - - S ko:K07089 - ko00000 permeases
EPKEEPDC_02103 8.45e-203 ycgS - - I - - - alpha/beta hydrolase fold
EPKEEPDC_02104 1.93e-241 ycgT 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
EPKEEPDC_02105 0.0 nasF 2.1.1.107, 4.2.1.75 - H ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
EPKEEPDC_02106 1.2e-74 nasE 1.7.1.15 - P ko:K00363 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Nitrite reductase
EPKEEPDC_02107 0.0 nasD 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EPKEEPDC_02108 0.0 nasC - - C ko:K00372 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EPKEEPDC_02109 0.0 nasB 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Assimilatory nitrate reductase (electron transfer subunit)
EPKEEPDC_02110 3.18e-282 nasA - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
EPKEEPDC_02111 1.22e-221 folE2 3.5.4.16 - S ko:K09007 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Converts GTP to 7,8-dihydroneopterin triphosphate
EPKEEPDC_02112 3.14e-130 - - - M - - - ErfK YbiS YcfS YnhG
EPKEEPDC_02113 1.08e-287 yciC - - S - - - GTPases (G3E family)
EPKEEPDC_02114 1.73e-148 yckA - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
EPKEEPDC_02115 1.53e-186 yckB - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
EPKEEPDC_02117 1.64e-98 yckC - - S - - - membrane
EPKEEPDC_02118 9.74e-67 yckD - - S - - - Protein of unknown function (DUF2680)
EPKEEPDC_02119 7.43e-58 - - - K - - - MarR family
EPKEEPDC_02120 9e-32 - - - - - - - -
EPKEEPDC_02121 1.16e-154 - - - S - - - AAA domain
EPKEEPDC_02122 0.0 yckE 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
EPKEEPDC_02123 5.81e-92 nin - - S - - - Competence protein J (ComJ)
EPKEEPDC_02124 1.27e-96 nucA - - M - - - Deoxyribonuclease NucA/NucB
EPKEEPDC_02125 1.24e-266 tlpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
EPKEEPDC_02126 5.38e-125 hxlB 5.3.1.27 - G ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
EPKEEPDC_02127 9.74e-138 hxlA 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 3-hexulose-6-phosphate synthase
EPKEEPDC_02128 6.05e-86 hxlR - - K - - - transcriptional
EPKEEPDC_02129 0.0 srfAA - - Q ko:K15654,ko:K15655,ko:K16119 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EPKEEPDC_02130 0.0 srfAB - - Q ko:K15654,ko:K15655,ko:K16120 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EPKEEPDC_02131 0.0 srfAC - - Q ko:K15656,ko:K16121 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 COG1020 Non-ribosomal peptide synthetase modules and related proteins
EPKEEPDC_02132 7.77e-178 srfAD - - Q ko:K15657 ko02024,map02024 ko00000,ko00001,ko01008 thioesterase
EPKEEPDC_02133 2.66e-289 - - - EGP - - - Major Facilitator Superfamily
EPKEEPDC_02134 3.91e-118 - - - S - - - YcxB-like protein
EPKEEPDC_02135 1.33e-204 ycxC - - EG - - - EamA-like transporter family
EPKEEPDC_02136 0.0 ycxD - - K - - - GntR family transcriptional regulator
EPKEEPDC_02137 2.02e-146 sfp - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
EPKEEPDC_02138 8.71e-148 yczE - - S ko:K07149 - ko00000 membrane
EPKEEPDC_02139 2.04e-171 tcyC - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
EPKEEPDC_02140 4.6e-157 tcyB - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
EPKEEPDC_02141 3.03e-188 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
EPKEEPDC_02142 5.32e-209 yclA - - K ko:K21755 - ko00000,ko03000 LysR substrate binding domain
EPKEEPDC_02143 2.24e-140 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
EPKEEPDC_02144 0.0 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
EPKEEPDC_02145 9.86e-53 - 4.1.1.61 - S ko:K21759 ko00627,ko01120,ko01220,map00627,map01120,map01220 ko00000,ko00001,ko01000 response to toxic substance
EPKEEPDC_02146 1.45e-107 yclD - - - - - - -
EPKEEPDC_02147 2.06e-197 yclE 3.4.11.5 - S ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Alpha beta hydrolase
EPKEEPDC_02148 0.0 dtpT - - E ko:K03305 - ko00000 amino acid peptide transporter
EPKEEPDC_02149 0.0 yclG - - M - - - Pectate lyase superfamily protein
EPKEEPDC_02151 0.0 gerKA - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
EPKEEPDC_02152 3.21e-285 gerKC - - S ko:K06297 - ko00000 spore germination
EPKEEPDC_02153 3.33e-247 gerKB - - F ko:K06296 - ko00000,ko02000 Spore germination protein
EPKEEPDC_02154 3.39e-155 yclH - - P ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
EPKEEPDC_02155 1.07e-277 yclI - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease) YclI
EPKEEPDC_02156 6.39e-165 yclJ - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EPKEEPDC_02157 0.0 yclK - - T - - - HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
EPKEEPDC_02158 2.18e-97 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
EPKEEPDC_02160 1.58e-05 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
EPKEEPDC_02162 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
EPKEEPDC_02163 1.09e-205 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EPKEEPDC_02164 4.69e-211 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EPKEEPDC_02165 2.29e-175 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
EPKEEPDC_02166 4.69e-212 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
EPKEEPDC_02167 0.0 ycnB - - EGP - - - the major facilitator superfamily
EPKEEPDC_02168 7.15e-199 ycnC - - K - - - Transcriptional regulator
EPKEEPDC_02169 2.12e-174 - 1.5.1.39 - C ko:K10678,ko:K19286 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 ko00000,ko00001,ko01000 Oxidoreductase
EPKEEPDC_02170 1.68e-60 ycnE - - S - - - Monooxygenase
EPKEEPDC_02171 6.51e-69 yczG - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
EPKEEPDC_02172 0.0 gabR - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EPKEEPDC_02173 1.33e-310 gabT 2.6.1.19, 2.6.1.22 - E ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EPKEEPDC_02174 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
EPKEEPDC_02175 2.76e-169 - - - L ko:K07497 - ko00000 Molecular Function DNA binding, Biological Process DNA recombination
EPKEEPDC_02176 7.42e-144 - - - V ko:K20485 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 ABC-type multidrug transport system, ATPase and permease
EPKEEPDC_02180 1.67e-190 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
EPKEEPDC_02181 2.69e-183 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EPKEEPDC_02182 3.99e-134 ycnI - - S - - - protein conserved in bacteria
EPKEEPDC_02183 0.0 ycnJ - - P ko:K14166 - ko00000,ko02000 protein, homolog of Cu resistance protein CopC
EPKEEPDC_02184 1e-136 ycnK - - K ko:K21601 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
EPKEEPDC_02185 4.67e-75 - - - - - - - -
EPKEEPDC_02186 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG2213 Phosphotransferase system, mannitol-specific IIBC component
EPKEEPDC_02187 8.3e-95 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
EPKEEPDC_02188 2.44e-265 mtlD 1.1.1.17 - G ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 COG0246 Mannitol-1-phosphate altronate dehydrogenases
EPKEEPDC_02189 8.33e-256 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Tartrate dehydrogenase
EPKEEPDC_02190 1.46e-95 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
EPKEEPDC_02191 5.45e-112 - - - Q - - - COG0412 Dienelactone hydrolase and related enzymes
EPKEEPDC_02192 2.29e-88 ycsD 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
EPKEEPDC_02194 1.9e-177 ycsE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
EPKEEPDC_02195 1.1e-180 ycsF - - S ko:K07160 - ko00000 Belongs to the UPF0271 (lamB) family
EPKEEPDC_02196 2.78e-273 ycsG - - P - - - COG1914 Mn2 and Fe2 transporters of the NRAMP family
EPKEEPDC_02197 1.65e-188 ycsI - - S - - - Belongs to the D-glutamate cyclase family
EPKEEPDC_02198 1.97e-170 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
EPKEEPDC_02199 1.29e-234 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
EPKEEPDC_02200 1.55e-170 kipR - - K - - - Transcriptional regulator
EPKEEPDC_02201 4.69e-151 ycsK - - E - - - anatomical structure formation involved in morphogenesis
EPKEEPDC_02203 8.97e-65 yczJ - - S - - - biosynthesis
EPKEEPDC_02204 0.0 pbpC 3.4.16.4 - M ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 Penicillin-binding Protein
EPKEEPDC_02205 1e-218 ycsN - - S - - - Oxidoreductase
EPKEEPDC_02206 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 transcriptional regulator, MtlR
EPKEEPDC_02207 0.0 ydaB - - IQ - - - acyl-CoA ligase
EPKEEPDC_02208 1.17e-126 ydaC - - Q - - - Methyltransferase domain
EPKEEPDC_02209 1.07e-206 ydaD - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EPKEEPDC_02210 2.75e-125 ydaE 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
EPKEEPDC_02211 1.1e-132 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
EPKEEPDC_02212 1.06e-100 ydaG - - S - - - general stress protein
EPKEEPDC_02213 1.87e-178 amj - - U - - - Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
EPKEEPDC_02214 1.09e-61 ydzA - - EGP - - - Domain of unknown function (DUF3817)
EPKEEPDC_02215 3.95e-98 lrpC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
EPKEEPDC_02216 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EPKEEPDC_02217 9.49e-262 ydaJ - - M - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
EPKEEPDC_02218 6.34e-193 ydaK - - T - - - Diguanylate cyclase, GGDEF domain
EPKEEPDC_02219 0.0 ydaL - - S - - - Uncharacterized protein conserved in bacteria (DUF2334)
EPKEEPDC_02220 1.12e-303 ydaM - - M - - - Glycosyl transferase family group 2
EPKEEPDC_02221 0.0 ydaN - - S - - - Bacterial cellulose synthase subunit
EPKEEPDC_02222 0.0 ydaO - - E - - - amino acid
EPKEEPDC_02223 5.98e-100 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
EPKEEPDC_02224 0.0 ydaP 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
EPKEEPDC_02225 7.18e-52 - - - - - - - -
EPKEEPDC_02226 3.9e-286 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
EPKEEPDC_02227 1.67e-42 ydaS - - S - - - membrane
EPKEEPDC_02228 2.25e-100 ydaT - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
EPKEEPDC_02229 2.05e-188 ydbA - - P - - - EcsC protein family
EPKEEPDC_02230 8.37e-11 gsiB - - S ko:K06884 - ko00000 general stress protein
EPKEEPDC_02231 7.58e-79 ydbB - - G - - - Cupin domain
EPKEEPDC_02232 1.28e-82 ydbC - - S - - - Domain of unknown function (DUF4937
EPKEEPDC_02233 6.41e-197 ydbD - - P ko:K07217 - ko00000 Catalase
EPKEEPDC_02234 3.66e-253 dctB - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
EPKEEPDC_02235 0.0 dctS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
EPKEEPDC_02236 4.82e-155 dctR - - T ko:K02475,ko:K11692 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
EPKEEPDC_02237 6.29e-290 dctA - - U ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
EPKEEPDC_02238 1.32e-230 ydbI - - S - - - AI-2E family transporter
EPKEEPDC_02239 4.59e-219 ydbJ - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EPKEEPDC_02240 2.99e-159 ydbK - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
EPKEEPDC_02241 9.32e-70 ydbL - - - - - - -
EPKEEPDC_02242 2.49e-278 ydbM - - I - - - acyl-CoA dehydrogenase
EPKEEPDC_02243 1.49e-26 - - - S - - - Fur-regulated basic protein B
EPKEEPDC_02245 2.72e-202 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EPKEEPDC_02246 4.19e-75 ydbP - - CO - - - Thioredoxin
EPKEEPDC_02247 8.43e-256 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
EPKEEPDC_02248 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
EPKEEPDC_02249 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
EPKEEPDC_02250 2.12e-107 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
EPKEEPDC_02251 0.0 ydbT - - S ko:K08981 - ko00000 Membrane
EPKEEPDC_02252 3.6e-139 ydcA - - S - - - membrane protein (homolog of Drosophila rhomboid)
EPKEEPDC_02253 1.32e-76 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
EPKEEPDC_02254 4.66e-234 ydcC - - M - - - COG2834 Outer membrane lipoprotein-sorting protein
EPKEEPDC_02255 1.77e-282 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EPKEEPDC_02256 9.49e-57 ndoAI - - K ko:K07723 - ko00000,ko02048,ko03000 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
EPKEEPDC_02257 4.34e-75 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
EPKEEPDC_02258 8.58e-184 rsbR - - T ko:K17763 - ko00000,ko03021 Positive regulator of sigma-B
EPKEEPDC_02259 1.8e-74 rsbS - - T ko:K17762 - ko00000,ko03021 antagonist
EPKEEPDC_02260 2.45e-89 rsbT 2.7.11.1 - T ko:K17752 - ko00000,ko01000,ko01001,ko03021 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
EPKEEPDC_02261 1.08e-242 rsbU 3.1.3.3 - KT ko:K07315 - ko00000,ko01000,ko03021 phosphatase
EPKEEPDC_02262 3.98e-70 rsbV - - T ko:K04749 - ko00000,ko03021 Belongs to the anti-sigma-factor antagonist family
EPKEEPDC_02263 8.3e-110 rsbW 2.7.11.1 - F ko:K04757 - ko00000,ko01000,ko01001,ko03021 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
EPKEEPDC_02264 1.55e-178 sigB - - K ko:K03090 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EPKEEPDC_02265 2.17e-140 rsbX 3.1.3.3 - KT ko:K05518 - ko00000,ko01000,ko03021 Sigma factor PP2C-like phosphatases
EPKEEPDC_02269 1.32e-106 ydcG - - S - - - EVE domain
EPKEEPDC_02270 1.79e-100 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
EPKEEPDC_02271 0.0 tex - - K ko:K06959 - ko00000 COG2183 Transcriptional accessory protein
EPKEEPDC_02272 3.74e-108 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
EPKEEPDC_02280 1.47e-268 ydcL - - L - - - Belongs to the 'phage' integrase family
EPKEEPDC_02281 4.73e-118 - - - E - - - IrrE N-terminal-like domain
EPKEEPDC_02282 1.91e-81 - - - K - - - Transcriptional
EPKEEPDC_02283 8.96e-24 - - - - - - - -
EPKEEPDC_02284 9.17e-54 - - - - - - - -
EPKEEPDC_02286 6.04e-43 - - - S - - - Bacterial protein of unknown function (DUF961)
EPKEEPDC_02287 1.33e-119 - - - M - - - Cysteine-rich secretory protein family
EPKEEPDC_02288 0.0 ydcQ - - D ko:K03466 - ko00000,ko03036 Ftsk spoiiie family protein
EPKEEPDC_02289 1.9e-256 nicK - - L ko:K07467 - ko00000 Replication initiation factor
EPKEEPDC_02291 1.72e-54 yddA - - - - - - -
EPKEEPDC_02294 7.6e-216 yddB - - S - - - Conjugative transposon protein TcpC
EPKEEPDC_02295 4.84e-54 yddC - - - - - - -
EPKEEPDC_02296 2.06e-119 yddD - - S - - - TcpE family
EPKEEPDC_02297 0.0 yddE - - S - - - AAA-like domain
EPKEEPDC_02298 1.34e-72 - - - S - - - Domain of unknown function (DUF1874)
EPKEEPDC_02299 0.0 yddG - - S - - - maturation of SSU-rRNA
EPKEEPDC_02300 7.54e-240 yddH - - M - - - Lysozyme-like
EPKEEPDC_02301 4.01e-105 yddI - - - - - - -
EPKEEPDC_02302 2.08e-57 yddJ - - S - - - Domain of unknown function with cystatin-like fold (DUF4467)
EPKEEPDC_02303 5.53e-110 - - - J - - - Domain of unknown function (DUF4209)
EPKEEPDC_02304 5.63e-91 - - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
EPKEEPDC_02308 2.33e-239 - - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EPKEEPDC_02309 8.15e-94 lrpA - - K ko:K03719 - ko00000,ko03000,ko03036 transcriptional
EPKEEPDC_02310 4.21e-100 lrpB - - K ko:K03719 - ko00000,ko03000,ko03036 transcriptional
EPKEEPDC_02311 1.62e-128 yddQ - - Q - - - Isochorismatase family
EPKEEPDC_02312 1.34e-184 yddR - - S - - - Zn-dependent hydrolases of the beta-lactamase fold
EPKEEPDC_02313 7.52e-285 ydeG3 - - EGP - - - Major Facilitator Superfamily
EPKEEPDC_02314 2.89e-84 - - - L - - - HNH nucleases
EPKEEPDC_02315 3.35e-245 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
EPKEEPDC_02316 4.22e-41 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock
EPKEEPDC_02317 3.57e-103 ydeB - - K ko:K07736 - ko00000,ko03000 Transcription factor
EPKEEPDC_02318 1.47e-211 - - - K - - - AraC-like ligand binding domain
EPKEEPDC_02319 7.92e-221 ydeD - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
EPKEEPDC_02320 9.2e-210 ydeE - - K ko:K13653 - ko00000,ko03000 AraC family transcriptional regulator
EPKEEPDC_02321 6.12e-23 - - - K - - - COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EPKEEPDC_02322 1.39e-291 - - - K - - - COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EPKEEPDC_02323 2.67e-277 ydeG - - EGP - - - Major facilitator superfamily
EPKEEPDC_02324 7.89e-71 ydeH - - - - - - -
EPKEEPDC_02325 6.71e-134 ydeI - - S - - - Bacteriocin-protection, YdeI or OmpD-Associated
EPKEEPDC_02326 4.13e-148 - - - - - - - -
EPKEEPDC_02327 5.21e-194 ydeK - - EG - - - -transporter
EPKEEPDC_02328 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EPKEEPDC_02329 2.49e-95 ydeM1 - - I - - - N-terminal half of MaoC dehydratase
EPKEEPDC_02330 2.81e-134 - - - S ko:K07002 - ko00000 Serine hydrolase
EPKEEPDC_02331 8.68e-74 - - - K - - - HxlR-like helix-turn-helix
EPKEEPDC_02332 6.56e-194 ydeO - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
EPKEEPDC_02333 8.61e-75 arsR - - K ko:K03892,ko:K22043 - ko00000,ko03000 transcriptional
EPKEEPDC_02334 3.38e-292 arsB - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EPKEEPDC_02335 1.51e-95 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Catalyzes the reduction of arsenate As(V) to arsenite As(III)
EPKEEPDC_02336 1.1e-184 - - - J - - - GNAT acetyltransferase
EPKEEPDC_02337 4.78e-191 - - - K - - - Transcriptional regulator
EPKEEPDC_02338 1.45e-157 nodB1 - - G - - - deacetylase
EPKEEPDC_02339 2.52e-199 - - - - - - - -
EPKEEPDC_02340 7.61e-279 - - - T - - - GHKL domain
EPKEEPDC_02341 3.89e-157 - - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
EPKEEPDC_02342 4.85e-191 - - - EG - - - EamA-like transporter family
EPKEEPDC_02343 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EPKEEPDC_02344 1.54e-232 - 4.1.1.86 - E ko:K13745 ko00260,ko01120,map00260,map01120 ko00000,ko00001,ko01000 Pyridoxal-dependent decarboxylase conserved domain
EPKEEPDC_02345 9.91e-150 ydfE - - S - - - Flavin reductase like domain
EPKEEPDC_02346 1.5e-158 ydfF - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
EPKEEPDC_02347 3.92e-104 - - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EPKEEPDC_02349 9.66e-252 ydfH 2.7.13.3 - T ko:K11623 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EPKEEPDC_02350 3.27e-142 ydfI - - K ko:K11624 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EPKEEPDC_02351 0.0 ydfJ - - S ko:K06994,ko:K11625 ko02020,map02020 ko00000,ko00001 drug exporters of the RND superfamily
EPKEEPDC_02352 1.31e-149 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
EPKEEPDC_02353 8.33e-187 - - - K - - - Bacterial transcription activator, effector binding domain
EPKEEPDC_02354 5e-197 ydfM - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EPKEEPDC_02355 1.51e-139 ydfN - - C ko:K15976 - ko00000,ko01000 nitroreductase
EPKEEPDC_02356 1.29e-236 ydfO - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
EPKEEPDC_02357 8.02e-84 ydfP - - S ko:K15977 - ko00000 DoxX
EPKEEPDC_02358 3.11e-73 ydfQ - - CO - - - Thioredoxin
EPKEEPDC_02359 2.4e-21 ydgA - - S - - - Spore germination protein gerPA/gerPF
EPKEEPDC_02360 3.22e-40 - - - - - - - -
EPKEEPDC_02362 9.11e-65 ydfR - - S - - - Protein of unknown function (DUF421)
EPKEEPDC_02363 9.94e-40 ydfR - - S - - - Protein of unknown function (DUF421)
EPKEEPDC_02364 8.96e-160 ydfS - - S - - - Protein of unknown function (DUF421)
EPKEEPDC_02365 2.57e-89 cotP - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
EPKEEPDC_02366 1.53e-47 ydgA - - S - - - Spore germination protein gerPA/gerPF
EPKEEPDC_02367 8.97e-47 ydgB - - S - - - Spore germination protein gerPA/gerPF
EPKEEPDC_02368 4.92e-127 ydgC - - K - - - Bacterial regulatory proteins, tetR family
EPKEEPDC_02369 6.73e-69 - - - S - - - DoxX-like family
EPKEEPDC_02370 3.51e-104 yycN - - K - - - Acetyltransferase
EPKEEPDC_02371 0.0 expZ - - S ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ABC transporter
EPKEEPDC_02372 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
EPKEEPDC_02373 1.4e-116 - - - S - - - DinB family
EPKEEPDC_02374 8.12e-104 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
EPKEEPDC_02375 0.0 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
EPKEEPDC_02376 6.42e-147 ydgI - - C - - - nitroreductase
EPKEEPDC_02377 3.29e-90 - - - K - - - Winged helix DNA-binding domain
EPKEEPDC_02378 9.46e-264 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
EPKEEPDC_02379 2.51e-155 ydhB - - S ko:K07090 - ko00000 membrane transporter protein
EPKEEPDC_02380 7.45e-158 ydhC - - K - - - FCD
EPKEEPDC_02381 2.1e-308 ydhD - - M - - - Glycosyl hydrolase
EPKEEPDC_02382 9.61e-290 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
EPKEEPDC_02383 6.08e-163 - - - - - - - -
EPKEEPDC_02384 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
EPKEEPDC_02385 2.26e-87 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
EPKEEPDC_02387 1.04e-105 - - - K - - - Acetyltransferase (GNAT) domain
EPKEEPDC_02388 6.35e-230 ydhJ - - S ko:K06885 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
EPKEEPDC_02389 2.59e-126 ydhK - - M - - - Protein of unknown function (DUF1541)
EPKEEPDC_02390 6.3e-255 ydhL - - EGP ko:K18567 - ko00000,ko02000 COG2814 Arabinose efflux permease
EPKEEPDC_02391 1.88e-63 ydhM 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EPKEEPDC_02392 3.39e-67 ydhN3 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EPKEEPDC_02393 2.27e-305 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EPKEEPDC_02394 0.0 ydhP 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
EPKEEPDC_02395 1.83e-169 ydhQ - - K ko:K03492 - ko00000,ko03000 UTRA
EPKEEPDC_02396 1.65e-212 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
EPKEEPDC_02397 8.45e-239 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
EPKEEPDC_02398 1.12e-269 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
EPKEEPDC_02399 4.02e-201 ydhU - - P ko:K07217 - ko00000 Catalase
EPKEEPDC_02402 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
EPKEEPDC_02405 3.38e-225 thiL 2.7.4.16 - H ko:K00946 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EPKEEPDC_02406 7.42e-112 ydiB - - S ko:K06925 - ko00000,ko03016 ATPase or kinase
EPKEEPDC_02407 3.14e-157 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214 Inactive homolog of metal-dependent proteases
EPKEEPDC_02408 1.41e-108 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
EPKEEPDC_02409 7.76e-240 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EPKEEPDC_02410 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter
EPKEEPDC_02411 1.46e-117 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
EPKEEPDC_02412 2.14e-148 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EPKEEPDC_02413 5.48e-31 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
EPKEEPDC_02414 3.55e-161 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EPKEEPDC_02415 3.2e-37 ydiK - - S - - - Domain of unknown function (DUF4305)
EPKEEPDC_02416 4.09e-165 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
EPKEEPDC_02417 2.14e-58 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EPKEEPDC_02418 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
EPKEEPDC_02419 5.85e-95 - - - L - - - Phage integrase family
EPKEEPDC_02420 4.63e-57 - - - L - - - Belongs to the 'phage' integrase family
EPKEEPDC_02422 1.31e-98 yddG - - S - - - maturation of SSU-rRNA
EPKEEPDC_02423 4.69e-26 yddG - - S - - - maturation of SSU-rRNA
EPKEEPDC_02424 5.47e-30 - - - S - - - branched-chain amino acid
EPKEEPDC_02425 1.85e-93 - - - E - - - AzlC protein
EPKEEPDC_02426 6.85e-201 gntR9 - - K - - - COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EPKEEPDC_02427 2.48e-18 - - - S - - - B3/4 domain
EPKEEPDC_02428 2.16e-215 megL 4.4.1.11 - E ko:K01761 ko00270,ko00450,map00270,map00450 ko00000,ko00001,ko01000 methionine gamma-lyase
EPKEEPDC_02429 3.29e-158 - - - I - - - Fatty acid desaturase
EPKEEPDC_02430 3.41e-18 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
EPKEEPDC_02431 2.57e-191 ydjC - - S - - - Abhydrolase domain containing 18
EPKEEPDC_02432 0.0 gutR - - K ko:K16247 - ko00000,ko03000 NB-ARC domain
EPKEEPDC_02433 4.32e-258 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
EPKEEPDC_02434 0.0 gutP - - G ko:K03292,ko:K16248 - ko00000,ko02000 MFS/sugar transport protein
EPKEEPDC_02435 5.78e-219 ydjE 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
EPKEEPDC_02436 1.08e-147 pspA - - KT ko:K03969 - ko00000 Phage shock protein A
EPKEEPDC_02437 7.04e-226 ydjG - - L - - - Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EPKEEPDC_02438 4.37e-165 ydjH - - S ko:K06872 - ko00000 COG1512 Beta-propeller domains of methanol dehydrogenase type
EPKEEPDC_02439 3.61e-203 ydjI - - S - - - virion core protein (lumpy skin disease virus)
EPKEEPDC_02440 1.95e-248 - - - S - - - Ion transport 2 domain protein
EPKEEPDC_02441 0.0 iolT - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
EPKEEPDC_02442 3.5e-249 ydjL 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
EPKEEPDC_02443 1.79e-84 ydjM - - M - - - Lytic transglycolase
EPKEEPDC_02444 1.14e-207 ydjN - - U - - - Involved in the tonB-independent uptake of proteins
EPKEEPDC_02446 9.99e-48 ydjO - - S - - - Cold-inducible protein YdjO
EPKEEPDC_02447 1.78e-202 - - - I - - - Alpha/beta hydrolase family
EPKEEPDC_02448 8.92e-225 yeaA - - S - - - Protein of unknown function (DUF4003)
EPKEEPDC_02449 0.0 cotA 1.16.3.3 - Q ko:K06324 - ko00000,ko01000 multicopper oxidases
EPKEEPDC_02450 0.0 gabP - - E ko:K11735 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
EPKEEPDC_02451 2.05e-197 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EPKEEPDC_02452 5.62e-226 yeaC - - S ko:K03924 - ko00000,ko01000 COG0714 MoxR-like ATPases
EPKEEPDC_02453 2.74e-286 yeaD - - S - - - conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
EPKEEPDC_02454 0.0 yebA - - E - - - COG1305 Transglutaminase-like enzymes
EPKEEPDC_02455 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
EPKEEPDC_02456 1.05e-109 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
EPKEEPDC_02457 0.0 - - - S - - - Domain of unknown function (DUF4179)
EPKEEPDC_02458 9.81e-283 pbuG - - S ko:K06901 - ko00000,ko02000 permease
EPKEEPDC_02459 5.85e-165 yebC - - M - - - Membrane
EPKEEPDC_02461 2.66e-120 yebE - - S - - - UPF0316 protein
EPKEEPDC_02462 3.13e-38 yebG - - S - - - NETI protein
EPKEEPDC_02463 1.08e-106 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EPKEEPDC_02464 2.21e-276 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EPKEEPDC_02465 6.85e-315 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EPKEEPDC_02466 2.78e-166 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
EPKEEPDC_02467 3.79e-52 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EPKEEPDC_02468 1.91e-166 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EPKEEPDC_02469 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EPKEEPDC_02470 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EPKEEPDC_02471 9.88e-240 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
EPKEEPDC_02472 3.62e-137 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EPKEEPDC_02473 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
EPKEEPDC_02474 1.63e-297 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
EPKEEPDC_02475 1.06e-95 - - - K - - - helix_turn_helix ASNC type
EPKEEPDC_02476 5.84e-292 - - - E ko:K16263 - ko00000,ko02000 Amino acid permease
EPKEEPDC_02477 3.45e-37 - - - S - - - Protein of unknown function (DUF2892)
EPKEEPDC_02478 0.0 yerA 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 adenine deaminase
EPKEEPDC_02479 2.35e-244 yerB - - S - - - Protein of unknown function (DUF3048) C-terminal domain
EPKEEPDC_02480 7.62e-68 yerC - - S - - - protein conserved in bacteria
EPKEEPDC_02481 0.0 yerD 1.4.7.1 - E ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 ko00000,ko00001,ko01000 Belongs to the glutamate synthase family
EPKEEPDC_02483 1.1e-161 pcrB - - I ko:K07094 - ko00000,ko01000 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
EPKEEPDC_02484 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
EPKEEPDC_02485 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EPKEEPDC_02486 2.07e-280 camS - - S - - - COG4851 Protein involved in sex pheromone biosynthesis
EPKEEPDC_02488 6.75e-248 yerI - - S - - - homoserine kinase type II (protein kinase fold)
EPKEEPDC_02489 2.29e-160 sapB - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
EPKEEPDC_02490 0.0 putP - - E ko:K03307,ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EPKEEPDC_02491 7.37e-61 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EPKEEPDC_02492 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
EPKEEPDC_02493 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EPKEEPDC_02494 7.45e-184 yerO - - K - - - Transcriptional regulator
EPKEEPDC_02495 0.0 swrC - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EPKEEPDC_02496 1.8e-218 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
EPKEEPDC_02497 0.0 rlmCD 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EPKEEPDC_02498 1.14e-27 - - - - - - - -
EPKEEPDC_02499 0.0 - - - K - - - SIR2-like domain
EPKEEPDC_02501 5.6e-125 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
EPKEEPDC_02502 1.15e-05 - - - - - - - -
EPKEEPDC_02503 4.69e-39 - - - S - - - Colicin immunity protein / pyocin immunity protein
EPKEEPDC_02505 8.88e-102 - - - S - - - Protein of unknown function, DUF600
EPKEEPDC_02506 1.56e-78 - - - S - - - Protein of unknown function, DUF600
EPKEEPDC_02507 0.0 - - - L - - - nucleic acid phosphodiester bond hydrolysis
EPKEEPDC_02509 1.4e-126 - - - L - - - endonuclease activity
EPKEEPDC_02510 7.9e-212 - 3.4.24.40 - CO ko:K01406 ko01503,map01503 ko00000,ko00001,ko01000,ko01002 amine dehydrogenase activity
EPKEEPDC_02511 3.56e-15 - - - S - - - Pfam:DUF1311
EPKEEPDC_02512 2.26e-267 rapH - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Tetratricopeptide repeat
EPKEEPDC_02514 6.29e-162 yeeN - - K - - - transcriptional regulatory protein
EPKEEPDC_02516 1.16e-128 dhaR3 - - K ko:K16137 - ko00000,ko03000 Transcriptional regulator
EPKEEPDC_02517 1.6e-103 yesE - - S ko:K06893 - ko00000 SnoaL-like domain
EPKEEPDC_02518 1.23e-195 yesF - - GM - - - NAD(P)H-binding
EPKEEPDC_02519 3.8e-60 cotJA - - S ko:K06332 - ko00000 Spore coat associated protein JA (CotJA)
EPKEEPDC_02520 2.31e-61 cotJB - - S ko:K06333 - ko00000 CotJB protein
EPKEEPDC_02521 3e-133 cotJC - - P ko:K06334 - ko00000 Spore Coat
EPKEEPDC_02522 2.8e-129 yesJ - - K - - - Acetyltransferase (GNAT) family
EPKEEPDC_02524 1.95e-132 yesL - - S - - - Protein of unknown function, DUF624
EPKEEPDC_02525 0.0 yesM 2.7.13.3 - T ko:K07718 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EPKEEPDC_02526 1.81e-253 - - - K ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, arabinose operon control protein
EPKEEPDC_02527 1.61e-311 yesO - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
EPKEEPDC_02528 5.79e-218 yesP - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
EPKEEPDC_02529 5.33e-212 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
EPKEEPDC_02530 9.34e-253 - 3.2.1.172 GH105 S ko:K15532 - ko00000,ko01000 Glycosyl Hydrolase Family 88
EPKEEPDC_02531 0.0 yesS - - K - - - Transcriptional regulator
EPKEEPDC_02532 1.63e-167 - - - E - - - GDSL-like Lipase/Acylhydrolase
EPKEEPDC_02533 5.08e-163 yesU - - S - - - Domain of unknown function (DUF1961)
EPKEEPDC_02534 1.64e-144 - - - S - - - Protein of unknown function, DUF624
EPKEEPDC_02535 0.0 - 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
EPKEEPDC_02536 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
EPKEEPDC_02538 3.72e-159 - - - E - - - GDSL-like Lipase/Acylhydrolase
EPKEEPDC_02539 0.0 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase activity
EPKEEPDC_02540 0.0 yetA - - - - - - -
EPKEEPDC_02541 0.0 lplA - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
EPKEEPDC_02542 3.25e-224 lplB - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
EPKEEPDC_02543 7.85e-209 - - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
EPKEEPDC_02544 0.0 - 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
EPKEEPDC_02545 1.81e-157 yetF - - S - - - membrane
EPKEEPDC_02546 5.46e-72 yetG 1.14.99.48 - S ko:K07145 ko00860,ko01110,map00860,map01110 ko00000,ko00001,ko01000 Antibiotic biosynthesis monooxygenase
EPKEEPDC_02547 2.47e-85 yetH - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EPKEEPDC_02548 1.75e-44 - - - - - - - -
EPKEEPDC_02549 4.37e-185 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
EPKEEPDC_02550 3.81e-28 yezD - - S - - - Uncharacterized small protein (DUF2292)
EPKEEPDC_02551 5.15e-135 yetJ - - S ko:K06890 - ko00000 Belongs to the BI1 family
EPKEEPDC_02552 2.04e-08 - - - EG - - - EamA-like transporter family
EPKEEPDC_02553 1.86e-114 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
EPKEEPDC_02554 1.26e-265 yetM - - CH - - - FAD binding domain
EPKEEPDC_02555 9.87e-173 - - - M - - - Membrane
EPKEEPDC_02556 4.11e-251 yetN - - S - - - Protein of unknown function (DUF3900)
EPKEEPDC_02557 0.0 cypD 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
EPKEEPDC_02558 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
EPKEEPDC_02559 9.83e-187 yfnH 2.7.7.33 - JM ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 ko00000,ko00001,ko01000 Nucleotidyl transferase
EPKEEPDC_02560 1.37e-219 yfnG 4.2.1.45, 4.2.1.46 - M ko:K01709,ko:K01710 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 dehydratase
EPKEEPDC_02561 5.22e-227 yfnF - - M - - - Nucleotide-diphospho-sugar transferase
EPKEEPDC_02562 2.44e-286 yfnE - - S - - - Glycosyltransferase like family 2
EPKEEPDC_02563 3.88e-242 yfnD - - M - - - Nucleotide-diphospho-sugar transferase
EPKEEPDC_02564 4.18e-266 fsr - - P ko:K08223 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
EPKEEPDC_02565 1.38e-163 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
EPKEEPDC_02566 2.4e-312 yfnA - - E ko:K03294 - ko00000 amino acid
EPKEEPDC_02567 0.0 yfmT 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
EPKEEPDC_02568 5.14e-161 yfmS - - NT - - - chemotaxis protein
EPKEEPDC_02569 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 COG0488 ATPase components of ABC transporters with duplicated ATPase domains
EPKEEPDC_02570 3.61e-96 yfmQ - - S - - - Uncharacterised protein from bacillus cereus group
EPKEEPDC_02571 3.54e-90 yfmP - - K ko:K21902 - ko00000,ko03000 transcriptional
EPKEEPDC_02572 2.42e-263 yfmO - - EGP ko:K08221 - ko00000,ko02000 Major facilitator superfamily
EPKEEPDC_02573 2.88e-46 - - - O - - - Subtilase family
EPKEEPDC_02574 9.1e-23 - - - - - - - -
EPKEEPDC_02576 3.95e-74 - - - - - - - -
EPKEEPDC_02577 0.0 yheS_1 - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
EPKEEPDC_02578 1.71e-262 yfmL - - L - - - COG0513 Superfamily II DNA and RNA helicases
EPKEEPDC_02579 1.86e-98 yfmK 2.3.1.128 - K ko:K03790 - ko00000,ko01000,ko03009 acetyltransferase
EPKEEPDC_02580 2.84e-240 yfmJ - - S ko:K07119 - ko00000 N-terminal domain of oxidoreductase
EPKEEPDC_02581 1.4e-192 fhuC 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
EPKEEPDC_02582 2.98e-223 fecD - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EPKEEPDC_02583 8.17e-221 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EPKEEPDC_02584 1.17e-220 yfmC - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
EPKEEPDC_02585 1.06e-31 - - - S - - - Protein of unknown function (DUF3212)
EPKEEPDC_02586 1.71e-76 yflT - - S - - - Heat induced stress protein YflT
EPKEEPDC_02587 2.01e-306 pel 4.2.2.2 - G ko:K01728 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
EPKEEPDC_02588 0.0 yflS - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
EPKEEPDC_02589 0.0 citS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
EPKEEPDC_02590 1.33e-152 citT - - T ko:K11638 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
EPKEEPDC_02591 3.98e-230 yflP - - S - - - Tripartite tricarboxylate transporter family receptor
EPKEEPDC_02592 5.35e-288 citM - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
EPKEEPDC_02593 1.7e-192 yflN - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
EPKEEPDC_02594 3.24e-274 nos 1.14.14.47 - C ko:K00491 ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the NOS family. Bacterial NOS oxygenase subfamily
EPKEEPDC_02595 2.97e-59 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
EPKEEPDC_02596 3.42e-157 yflK - - S - - - protein conserved in bacteria
EPKEEPDC_02597 1.29e-24 yflJ - - S - - - Protein of unknown function (DUF2639)
EPKEEPDC_02598 6.9e-27 yflI - - - - - - -
EPKEEPDC_02599 3.63e-66 yflH - - S - - - Protein of unknown function (DUF3243)
EPKEEPDC_02600 1.14e-178 yflG 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
EPKEEPDC_02601 0.0 nagE 2.7.1.193, 2.7.1.199 - G ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
EPKEEPDC_02602 0.0 yflE 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
EPKEEPDC_02603 2.2e-86 ydhN1 - - S - - - Domain of unknown function (DUF1992)
EPKEEPDC_02604 0.0 yflA - - E ko:K03310 - ko00000 Sodium alanine symporter
EPKEEPDC_02605 2.1e-247 yfkT - - E ko:K06309 - ko00000 Spore germination protein
EPKEEPDC_02607 2.66e-270 yfkR - - S ko:K06297,ko:K06308 - ko00000 spore germination
EPKEEPDC_02608 0.0 yfkQ - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
EPKEEPDC_02609 0.0 treP 2.7.1.201 - G ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EPKEEPDC_02610 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
EPKEEPDC_02611 1.24e-172 treR - - K ko:K03486 - ko00000,ko03000 transcriptional
EPKEEPDC_02612 6.16e-160 frp - - C - - - nitroreductase
EPKEEPDC_02613 0.0 yfkN 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K01119,ko:K06931,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
EPKEEPDC_02614 3.17e-113 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
EPKEEPDC_02615 1.46e-264 ydiN3 - - EGP - - - COG0477 Permeases of the major facilitator superfamily
EPKEEPDC_02616 5.99e-41 yfkK - - S - - - Belongs to the UPF0435 family
EPKEEPDC_02617 8.37e-108 yfkJ 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EPKEEPDC_02618 2.08e-66 yfkI - - S - - - gas vesicle protein
EPKEEPDC_02619 9.64e-184 yihY - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
EPKEEPDC_02620 1.64e-12 - - - - - - - -
EPKEEPDC_02621 1.9e-278 yfkF - - EGP - - - COG0477 Permeases of the major facilitator superfamily
EPKEEPDC_02622 1.34e-235 cax - - P ko:K07300 - ko00000,ko02000 COG0387 Ca2 H antiporter
EPKEEPDC_02623 3.69e-189 yfkD - - S - - - YfkD-like protein
EPKEEPDC_02624 4.44e-191 yfkC - - M - - - Mechanosensitive ion channel
EPKEEPDC_02625 1.76e-283 yfkA - - S - - - YfkB-like domain
EPKEEPDC_02626 3.26e-36 yfjT - - - - - - -
EPKEEPDC_02627 7.24e-198 pdaA - - G ko:K01567 - ko00000,ko01000 deacetylase
EPKEEPDC_02628 3.63e-189 yfjR - - I - - - NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
EPKEEPDC_02629 3.18e-236 corA - - P ko:K03284 - ko00000,ko02000 Mediates influx of magnesium ions
EPKEEPDC_02630 9.24e-213 yfjP 3.2.2.21 - L ko:K01247 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EPKEEPDC_02631 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EPKEEPDC_02632 3.31e-57 - - - S - - - YfzA-like protein
EPKEEPDC_02633 4.72e-241 yfjN - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EPKEEPDC_02634 3.74e-108 yfjM - - S - - - Psort location Cytoplasmic, score
EPKEEPDC_02635 1.36e-244 acoA - - C ko:K21416 - ko00000,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
EPKEEPDC_02636 1.59e-243 acoB - - C ko:K21417 - ko00000,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
EPKEEPDC_02637 1.82e-259 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
EPKEEPDC_02638 0.0 acoL 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
EPKEEPDC_02639 0.0 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
EPKEEPDC_02640 8.16e-36 sspH - - S ko:K06425 - ko00000 Belongs to the SspH family
EPKEEPDC_02641 7.42e-75 yfjF - - S ko:K09771 - ko00000,ko02000 UPF0060 membrane protein
EPKEEPDC_02642 2.16e-100 - - - S - - - Family of unknown function (DUF5381)
EPKEEPDC_02643 1.49e-131 yfjD - - S - - - Family of unknown function (DUF5381)
EPKEEPDC_02644 2.5e-185 yfjC - - - - - - -
EPKEEPDC_02645 5.56e-270 yfjB - - - - - - -
EPKEEPDC_02646 5.59e-61 yfjA - - S - - - Belongs to the WXG100 family
EPKEEPDC_02649 9.67e-25 - - - S - - - protein conserved in bacteria
EPKEEPDC_02651 1.77e-88 - - - S - - - LXG domain of WXG superfamily
EPKEEPDC_02654 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
EPKEEPDC_02655 5.03e-180 - - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
EPKEEPDC_02656 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EPKEEPDC_02657 0.0 yfiB3 - - V ko:K06147 - ko00000,ko02000 ABC transporter
EPKEEPDC_02658 0.0 yfiC3 - - V ko:K06147 - ko00000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
EPKEEPDC_02659 2.01e-84 yfiD3 - - S - - - DoxX
EPKEEPDC_02660 2.85e-206 yfiE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
EPKEEPDC_02661 3.4e-239 baeS - - T - - - Histidine kinase
EPKEEPDC_02662 8.27e-144 yfiK - - KT ko:K02479 - ko00000,ko02022 LuxR family transcriptional regulator
EPKEEPDC_02663 3.75e-215 drrA - - V ko:K01990,ko:K09695 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
EPKEEPDC_02664 6.49e-268 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
EPKEEPDC_02665 6.93e-262 - - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
EPKEEPDC_02666 1.89e-128 padR - - K - - - transcriptional
EPKEEPDC_02667 7.87e-128 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
EPKEEPDC_02668 2.68e-252 yfiQ - - G ko:K21462 - ko00000 COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
EPKEEPDC_02669 1.56e-125 yfiT - - S - - - Belongs to the metal hydrolase YfiT family
EPKEEPDC_02670 0.0 yfiU - - EGP - - - the major facilitator superfamily
EPKEEPDC_02671 2.11e-103 yfiV - - K - - - transcriptional
EPKEEPDC_02672 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EPKEEPDC_02673 6.35e-230 yfiY - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
EPKEEPDC_02674 8.91e-225 yfiZ - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EPKEEPDC_02675 7.36e-229 yfhA - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EPKEEPDC_02676 1.72e-211 yfhB - - S - - - PhzF family
EPKEEPDC_02677 2.87e-138 yfhC - - C - - - nitroreductase
EPKEEPDC_02678 8.86e-35 yfhD - - S - - - YfhD-like protein
EPKEEPDC_02680 1.54e-219 yfhF - - S ko:K07071 - ko00000 nucleoside-diphosphate sugar epimerase
EPKEEPDC_02681 1.88e-180 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
EPKEEPDC_02682 4.58e-69 yfhH - - S - - - Protein of unknown function (DUF1811)
EPKEEPDC_02684 4.94e-268 yfhI - - EGP - - - -transporter
EPKEEPDC_02685 2.25e-27 sspK - - S ko:K06428 - ko00000 reproduction
EPKEEPDC_02686 8.95e-60 yfhJ - - S - - - WVELL protein
EPKEEPDC_02687 1.91e-114 yfhK - - T - - - Bacterial SH3 domain homologues
EPKEEPDC_02688 6.3e-66 yfhL - - S - - - SdpI/YhfL protein family
EPKEEPDC_02689 6.53e-217 yfhM 3.8.1.5 - S ko:K01563 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Alpha beta hydrolase
EPKEEPDC_02690 3.43e-236 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
EPKEEPDC_02691 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
EPKEEPDC_02692 2.07e-236 yfhP - - S ko:K07038 - ko00000 membrane-bound metal-dependent
EPKEEPDC_02693 1.31e-265 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific
EPKEEPDC_02694 1.73e-48 yfhS - - - - - - -
EPKEEPDC_02695 3.13e-172 fabL 1.3.1.104 - IQ ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EPKEEPDC_02696 2.35e-14 sspE - - S ko:K06422 - ko00000 Small, acid-soluble spore protein, gamma-type
EPKEEPDC_02697 4.06e-49 ygaB - - S - - - YgaB-like protein
EPKEEPDC_02698 2.32e-135 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
EPKEEPDC_02699 0.0 ygaD - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
EPKEEPDC_02700 1.87e-238 ygaE - - S - - - Membrane
EPKEEPDC_02701 3.26e-312 gsaB 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
EPKEEPDC_02702 2.92e-113 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Peroxiredoxin
EPKEEPDC_02703 2.37e-104 perR - - P ko:K09825 - ko00000,ko03000 Belongs to the Fur family
EPKEEPDC_02704 3.38e-73 ygzB - - S - - - UPF0295 protein
EPKEEPDC_02705 2.36e-214 ygxA - - S - - - Nucleotidyltransferase-like
EPKEEPDC_02706 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
EPKEEPDC_02723 2.17e-65 - - - - - - - -
EPKEEPDC_02725 3.54e-77 - - - L ko:K07451,ko:K07453 - ko00000,ko01000,ko02048 HNH endonuclease
EPKEEPDC_02726 4.15e-65 - - - V ko:K07451 - ko00000,ko01000,ko02048 endonuclease activity
EPKEEPDC_02727 5.03e-182 spo0M - - S ko:K06377 - ko00000 COG4326 Sporulation control protein
EPKEEPDC_02728 1.58e-36 - - - - - - - -
EPKEEPDC_02729 2.93e-167 ygaJ 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
EPKEEPDC_02730 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EPKEEPDC_02732 0.0 katA 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
EPKEEPDC_02733 2.58e-178 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
EPKEEPDC_02734 6.93e-217 ssuA - - M ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Sulfonate ABC transporter
EPKEEPDC_02735 1.68e-189 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
EPKEEPDC_02736 5.41e-275 ssuD 1.14.14.28, 1.14.14.5 - C ko:K04091,ko:K20938 ko00920,map00920 ko00000,ko00001,ko01000 Catalyzes the desulfonation of aliphatic sulfonates
EPKEEPDC_02738 4.82e-55 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EPKEEPDC_02739 5.19e-98 ygaO - - - - - - -
EPKEEPDC_02740 1.48e-39 - - - K ko:K07729 - ko00000,ko03000 Transcriptional regulator
EPKEEPDC_02742 7.51e-145 yhzB - - S - - - B3/4 domain
EPKEEPDC_02743 1.2e-283 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EPKEEPDC_02744 1.6e-224 yhbB - - S - - - Putative amidase domain
EPKEEPDC_02745 1.87e-112 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
EPKEEPDC_02746 3.4e-143 yhbD - - K - - - Protein of unknown function (DUF4004)
EPKEEPDC_02747 1.32e-95 yhbE - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
EPKEEPDC_02748 2.46e-104 yhbF - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
EPKEEPDC_02749 0.0 prkA - - T ko:K07180 - ko00000 Ser protein kinase
EPKEEPDC_02750 1.21e-286 yhbH - - S ko:K09786 - ko00000 Belongs to the UPF0229 family
EPKEEPDC_02751 1.29e-101 yhbI - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
EPKEEPDC_02752 2.67e-133 yhbJ - - V - - - COG1566 Multidrug resistance efflux pump
EPKEEPDC_02753 0.0 yhcA - - EGP ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
EPKEEPDC_02754 4.87e-128 yhcB 1.6.5.2 - S ko:K03809 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 Belongs to the WrbA family
EPKEEPDC_02755 9.3e-58 yhcC - - - - - - -
EPKEEPDC_02757 2.06e-69 - - - - - - - -
EPKEEPDC_02758 1.67e-79 yhcF - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator
EPKEEPDC_02759 3.24e-156 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EPKEEPDC_02760 2.95e-209 yhcH - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EPKEEPDC_02761 1.15e-210 yhcI - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
EPKEEPDC_02762 1.91e-42 cspB - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
EPKEEPDC_02763 9.06e-194 metQ_3 - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
EPKEEPDC_02764 3.74e-247 yhcK 2.7.7.65 - T ko:K18967 - ko00000,ko01000,ko02000 COG2199 FOG GGDEF domain
EPKEEPDC_02765 2.62e-301 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
EPKEEPDC_02766 8.05e-113 - - - S - - - Protein of unknown function (DUF2812)
EPKEEPDC_02767 3.22e-65 - - - K - - - Transcriptional regulator PadR-like family
EPKEEPDC_02768 1.09e-61 yhcM - - - - - - -
EPKEEPDC_02769 9.32e-108 yhcN - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
EPKEEPDC_02770 3.12e-224 yhcP - - - - - - -
EPKEEPDC_02771 2.39e-146 yhcQ - - M - - - Spore coat protein
EPKEEPDC_02772 0.0 yhcR 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01081,ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
EPKEEPDC_02773 1.78e-134 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
EPKEEPDC_02774 4.78e-218 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
EPKEEPDC_02775 4.27e-89 yhcU - - S - - - Family of unknown function (DUF5365)
EPKEEPDC_02776 1.76e-90 yhcV - - S - - - COG0517 FOG CBS domain
EPKEEPDC_02777 2.5e-154 yhcW - - S ko:K07025 - ko00000 hydrolase
EPKEEPDC_02778 0.0 yhcX - - K - - - Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
EPKEEPDC_02779 0.0 yhxA - - E - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EPKEEPDC_02780 6.25e-134 glpP - - K ko:K02443 - ko00000,ko03000 Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EPKEEPDC_02781 4.68e-195 glpF - - G ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
EPKEEPDC_02782 0.0 glpK 2.7.1.30 - C ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EPKEEPDC_02783 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EPKEEPDC_02784 0.0 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
EPKEEPDC_02785 1.88e-272 yhcY 2.7.13.3 - T ko:K02480 - ko00000,ko01000,ko01001,ko02022 Histidine kinase
EPKEEPDC_02786 5.44e-144 yhcZ - - K ko:K02479 - ko00000,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EPKEEPDC_02787 6.64e-116 yhdA 1.7.1.6 - S ko:K03206 - ko00000,ko01000 NADPH-dependent FMN reductase
EPKEEPDC_02788 1.65e-51 yhdB - - S - - - YhdB-like protein
EPKEEPDC_02789 1.02e-71 yhdC - - S - - - Protein of unknown function (DUF3889)
EPKEEPDC_02790 2.29e-273 lytF - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
EPKEEPDC_02791 1.95e-99 nsrR - - K ko:K13771 ko05132,map05132 ko00000,ko00001,ko03000 Transcriptional regulator
EPKEEPDC_02792 1.44e-304 ygxB - - M - - - Conserved TM helix
EPKEEPDC_02793 0.0 spoVR - - S ko:K06415 - ko00000 Stage V sporulation protein R
EPKEEPDC_02794 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
EPKEEPDC_02795 1.45e-203 lytE - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
EPKEEPDC_02796 4.93e-210 citR - - K ko:K19242 - ko00000,ko03000 Transcriptional regulator
EPKEEPDC_02797 1.06e-260 citA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
EPKEEPDC_02798 1.58e-205 yhdF - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EPKEEPDC_02799 3.58e-316 yhdG - - E ko:K03294 - ko00000 amino acid
EPKEEPDC_02800 1.01e-308 yhdH - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
EPKEEPDC_02801 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EPKEEPDC_02802 1.75e-100 - - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EPKEEPDC_02803 4.27e-59 yhdK - - S - - - Sigma-M inhibitor protein
EPKEEPDC_02804 1.02e-256 yhdL - - S - - - Sigma factor regulator N-terminal
EPKEEPDC_02805 3.24e-113 sigM - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
EPKEEPDC_02806 6.74e-244 yhdN - - C - - - Aldo keto reductase
EPKEEPDC_02807 3.9e-143 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
EPKEEPDC_02808 2.18e-304 yhdP - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
EPKEEPDC_02809 3.44e-97 cueR - - K ko:K11923 - ko00000,ko03000 transcriptional
EPKEEPDC_02810 5.1e-284 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
EPKEEPDC_02811 0.0 yhdT - - P - - - COG1253 Hemolysins and related proteins containing CBS domains
EPKEEPDC_02812 2.48e-66 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EPKEEPDC_02813 1.67e-86 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EPKEEPDC_02814 9.03e-173 yhdW 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
EPKEEPDC_02815 3.7e-09 yhdX - - S - - - Uncharacterized protein YhdX
EPKEEPDC_02816 9.73e-239 yhdY - - M ko:K16052 - ko00000,ko02000 Mechanosensitive ion channel
EPKEEPDC_02817 3.99e-178 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
EPKEEPDC_02818 3.54e-194 nodB1 - - G - - - deacetylase
EPKEEPDC_02819 3.16e-197 dat 2.6.1.21 - E ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
EPKEEPDC_02820 8.48e-302 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter
EPKEEPDC_02821 1.53e-108 nhaX - - T - - - Belongs to the universal stress protein A family
EPKEEPDC_02822 0.0 yheI - - V ko:K18216,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
EPKEEPDC_02823 0.0 yheH - - V ko:K06147,ko:K18217,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
EPKEEPDC_02824 3.18e-141 yheG - - GM - - - NAD(P)H-binding
EPKEEPDC_02825 1.25e-38 sspB - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
EPKEEPDC_02826 2.27e-49 yheE - - S - - - Family of unknown function (DUF5342)
EPKEEPDC_02827 0.0 yheD - - HJ - - - YheC/D like ATP-grasp
EPKEEPDC_02828 1.32e-273 yheC - - HJ - - - YheC/D like ATP-grasp
EPKEEPDC_02829 4.16e-259 yheB - - S - - - Belongs to the UPF0754 family
EPKEEPDC_02830 7.46e-72 yheA - - S - - - Belongs to the UPF0342 family
EPKEEPDC_02831 1.58e-262 yhaZ - - L - - - DNA alkylation repair enzyme
EPKEEPDC_02832 8.7e-198 yhaX - - S - - - haloacid dehalogenase-like hydrolase
EPKEEPDC_02833 0.0 hemZ - - H - - - coproporphyrinogen III oxidase
EPKEEPDC_02834 1.52e-266 yhaU - - P ko:K03455 - ko00000 COG0475 Kef-type K transport systems, membrane components
EPKEEPDC_02835 6.51e-114 - - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
EPKEEPDC_02837 1.79e-169 yhaR - - I - - - enoyl-CoA hydratase
EPKEEPDC_02838 2.29e-36 - - - S - - - YhzD-like protein
EPKEEPDC_02839 1.86e-213 yhaQ - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EPKEEPDC_02840 5.14e-272 yhaP - - CP ko:K01992 - ko00000,ko00002,ko02000 COG1668 ABC-type Na efflux pump, permease component
EPKEEPDC_02841 9.44e-301 yhaO - - L ko:K03547 - ko00000,ko03400 DNA repair exonuclease
EPKEEPDC_02842 0.0 yhaN - - L - - - AAA domain
EPKEEPDC_02843 2.13e-227 yhaM - - L ko:K03698 - ko00000,ko01000,ko03019 Shows a 3'-5' exoribonuclease activity
EPKEEPDC_02844 1.88e-39 yhaL - - S - - - Sporulation protein YhaL
EPKEEPDC_02845 8.42e-161 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
EPKEEPDC_02846 1.4e-116 yhaK - - S - - - Putative zincin peptidase
EPKEEPDC_02847 8.48e-73 yhaI - - S - - - Protein of unknown function (DUF1878)
EPKEEPDC_02848 4.92e-148 hpr - - K ko:K09682 - ko00000,ko03000 Negative regulator of protease production and sporulation
EPKEEPDC_02849 3.89e-54 yhaH - - S - - - YtxH-like protein
EPKEEPDC_02850 9.66e-30 - - - - - - - -
EPKEEPDC_02851 1.28e-103 trpP - - S - - - Tryptophan transporter TrpP
EPKEEPDC_02852 2.51e-260 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EPKEEPDC_02853 3.5e-106 hit - - FG ko:K02503 - ko00000,ko04147 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
EPKEEPDC_02854 6.35e-175 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 transporter (ATP-binding protein)
EPKEEPDC_02855 3.11e-272 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
EPKEEPDC_02856 8.29e-161 ecsC - - S - - - EcsC protein family
EPKEEPDC_02857 5.37e-292 yhaA - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
EPKEEPDC_02858 3.27e-311 yhfA - - C - - - membrane
EPKEEPDC_02859 1e-44 - - - C - - - Rubrerythrin
EPKEEPDC_02860 1.31e-118 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
EPKEEPDC_02861 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
EPKEEPDC_02862 1.24e-257 hemE 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EPKEEPDC_02863 3.99e-230 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
EPKEEPDC_02864 0.0 hemY 1.3.3.15, 1.3.3.4 - H ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EPKEEPDC_02865 1e-132 yhgD - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
EPKEEPDC_02866 0.0 yhgE - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
EPKEEPDC_02867 3.57e-236 fabHB 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EPKEEPDC_02868 3.8e-177 yhfC - - S - - - Putative membrane peptidase family (DUF2324)
EPKEEPDC_02869 1.55e-252 yhfE - - G - - - peptidase M42
EPKEEPDC_02870 1.53e-93 - - - S - - - ASCH
EPKEEPDC_02871 4.77e-289 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
EPKEEPDC_02872 8.42e-183 yhfI - - S - - - COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
EPKEEPDC_02873 4.06e-245 lplJ 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
EPKEEPDC_02874 8.31e-141 yhfK - - GM - - - NmrA-like family
EPKEEPDC_02875 0.0 yhfL 6.2.1.3 - IQ ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
EPKEEPDC_02876 2.28e-84 yhfM - - - - - - -
EPKEEPDC_02877 6.5e-306 yhfN - - O - - - Peptidase M48
EPKEEPDC_02878 6.91e-260 aprE 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
EPKEEPDC_02879 4.38e-102 - - - K - - - acetyltransferase
EPKEEPDC_02880 2.4e-232 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Quinone oxidoreductase
EPKEEPDC_02881 1.32e-221 yhfQ - - M ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
EPKEEPDC_02882 2.27e-139 yhfR 5.4.2.12 - G ko:K15634,ko:K15640 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
EPKEEPDC_02883 5.18e-251 yhfS 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
EPKEEPDC_02884 0.0 vraA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
EPKEEPDC_02885 1.47e-118 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
EPKEEPDC_02886 4.33e-259 hemAT - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
EPKEEPDC_02887 0.0 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
EPKEEPDC_02888 2.24e-203 yhxC - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EPKEEPDC_02889 9.84e-45 yhzC - - S - - - IDEAL
EPKEEPDC_02890 6.29e-141 comK - - K ko:K02250 ko02024,map02024 ko00000,ko00001,ko02044,ko03000 Competence transcription factor
EPKEEPDC_02891 2.55e-216 yhxD - - IQ - - - Enoyl-(Acyl carrier protein) reductase
EPKEEPDC_02892 1.38e-54 yhjA - - S - - - Excalibur calcium-binding domain
EPKEEPDC_02893 0.0 yhjB - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EPKEEPDC_02894 1.61e-36 yhjC - - S - - - Protein of unknown function (DUF3311)
EPKEEPDC_02895 8.34e-78 yhjD - - - - - - -
EPKEEPDC_02896 4.87e-141 yhjE - - S - - - SNARE associated Golgi protein
EPKEEPDC_02897 3.09e-118 spsB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
EPKEEPDC_02898 0.0 yhjG - - CH - - - FAD binding domain
EPKEEPDC_02899 6.39e-119 yhjH - - K - - - helix_turn_helix multiple antibiotic resistance protein
EPKEEPDC_02902 2.11e-270 glcP - - G ko:K08174 - ko00000,ko02000 Major Facilitator Superfamily
EPKEEPDC_02903 6.61e-256 - 1.1.1.18, 1.1.1.361, 1.1.1.369 - S ko:K00010,ko:K18652 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
EPKEEPDC_02904 5.31e-205 ntdB 3.1.3.24, 3.1.3.92 - S ko:K07024,ko:K18654 ko00500,map00500 ko00000,ko00001,ko01000 Sucrose-6F-phosphate phosphohydrolase
EPKEEPDC_02905 0.0 - 2.6.1.104 - E ko:K18653 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
EPKEEPDC_02906 1.46e-237 yhjM - - K - - - Transcriptional regulator
EPKEEPDC_02907 2.05e-258 yhjN - - S ko:K07120 - ko00000 membrane
EPKEEPDC_02908 1.69e-261 - - - EGP - - - Transmembrane secretion effector
EPKEEPDC_02909 0.0 - - - S - - - Sugar transport-related sRNA regulator N-term
EPKEEPDC_02910 9.3e-102 yhjR - - S - - - Rubrerythrin
EPKEEPDC_02911 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 ATP-dependent helicase deoxyribonuclease subunit B
EPKEEPDC_02912 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
EPKEEPDC_02913 1.4e-280 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
EPKEEPDC_02914 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 COG0419 ATPase involved in DNA repair
EPKEEPDC_02915 2.61e-64 yisB - - V - - - COG1403 Restriction endonuclease
EPKEEPDC_02916 3.3e-43 gerPF - - S ko:K06299,ko:K06304 - ko00000 Spore germination protein gerPA/gerPF
EPKEEPDC_02917 9.24e-85 gerPE - - S ko:K06303 - ko00000 Spore germination protein GerPE
EPKEEPDC_02918 6.07e-33 gerPD - - S ko:K06302 - ko00000 Spore germination protein
EPKEEPDC_02919 3.34e-92 gerPC - - S ko:K06301 - ko00000 Spore germination protein
EPKEEPDC_02920 3.87e-42 gerPB - - S ko:K06300 - ko00000 cell differentiation
EPKEEPDC_02921 1.82e-45 gerPA - - S ko:K06299 - ko00000 Spore germination protein
EPKEEPDC_02922 1.52e-32 yisI - - S - - - Spo0E like sporulation regulatory protein
EPKEEPDC_02923 1.09e-221 cotH - - M ko:K06330 - ko00000 Spore Coat
EPKEEPDC_02924 2.66e-219 yisK - - Q - - - COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
EPKEEPDC_02925 1.02e-74 yisL - - S - - - UPF0344 protein
EPKEEPDC_02926 0.0 wprA - - O ko:K13274 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
EPKEEPDC_02927 8.67e-131 yisN - - S - - - Protein of unknown function (DUF2777)
EPKEEPDC_02928 0.0 asnO 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
EPKEEPDC_02929 6.22e-114 yizA - - S - - - Damage-inducible protein DinB
EPKEEPDC_02930 5.37e-190 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 phytoene
EPKEEPDC_02931 2.91e-310 yisQ - - V - - - Mate efflux family protein
EPKEEPDC_02932 6.71e-206 yisR - - K - - - Transcriptional regulator
EPKEEPDC_02933 6.13e-234 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
EPKEEPDC_02934 4.25e-248 yisS 1.1.1.18, 1.1.1.369, 1.1.1.370 - S ko:K00010,ko:K16043 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
EPKEEPDC_02935 1.72e-120 yisT - - S - - - DinB family
EPKEEPDC_02936 1.05e-137 argO - - S ko:K06895 - ko00000,ko02000 Lysine exporter protein LysE YggA
EPKEEPDC_02937 3.77e-50 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EPKEEPDC_02938 2.42e-249 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EPKEEPDC_02939 1.76e-95 yisX - - S - - - Pentapeptide repeats (9 copies)
EPKEEPDC_02940 5.29e-198 yisY 1.11.1.10 - I ko:K00433 - ko00000,ko01000 hydrolases or acyltransferases (alpha beta hydrolase superfamily)
EPKEEPDC_02941 4.06e-145 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
EPKEEPDC_02942 7.62e-293 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
EPKEEPDC_02943 1.58e-183 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
EPKEEPDC_02944 2.29e-154 - 3.1.3.71 - H ko:K05979 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the ComB family
EPKEEPDC_02945 7.15e-179 yitD 4.4.1.19 - S ko:K08097 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko00002,ko01000 synthase
EPKEEPDC_02946 6.77e-145 yitE - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
EPKEEPDC_02947 4.32e-283 yitF 5.5.1.27 - M ko:K18983 ko00053,map00053 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
EPKEEPDC_02948 8.28e-291 yitG - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
EPKEEPDC_02949 1.29e-196 yitH - - K - - - Acetyltransferase (GNAT) domain
EPKEEPDC_02950 2.16e-93 - - - S - - - Acetyltransferase (GNAT) domain
EPKEEPDC_02951 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
EPKEEPDC_02952 1.75e-76 yitK - - S ko:K09767 - ko00000 Belongs to the UPF0234 family
EPKEEPDC_02953 2.26e-203 yitL - - S ko:K00243 - ko00000 protein conserved in bacteria
EPKEEPDC_02954 4.16e-122 - - - - - - - -
EPKEEPDC_02955 1.42e-218 - - - - - - - -
EPKEEPDC_02956 3.29e-127 - - - S - - - Sporulation delaying protein SdpA
EPKEEPDC_02957 8.46e-77 - - - K - - - Transcriptional regulator PadR-like family
EPKEEPDC_02958 3.53e-119 - - - - - - - -
EPKEEPDC_02959 4.59e-59 yitR - - S - - - Domain of unknown function (DUF3784)
EPKEEPDC_02960 0.0 nprB 3.4.24.28 - E ko:K01400,ko:K08777 ko02024,map02024 ko00000,ko00001,ko01000,ko01002 Peptidase M4
EPKEEPDC_02961 2.62e-201 yitS - - S - - - protein conserved in bacteria
EPKEEPDC_02962 2.29e-189 yitT - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
EPKEEPDC_02963 1.96e-93 ipi - - S - - - Intracellular proteinase inhibitor
EPKEEPDC_02964 1.01e-25 - - - S - - - Protein of unknown function (DUF3813)
EPKEEPDC_02965 1.52e-198 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
EPKEEPDC_02966 5.05e-185 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
EPKEEPDC_02967 4.63e-68 yitW - - S - - - metal-sulfur cluster biosynthetic enzyme
EPKEEPDC_02968 1.74e-31 - - - S - - - Proteolipid membrane potential modulator
EPKEEPDC_02969 0.0 yitY - - C - - - D-arabinono-1,4-lactone oxidase
EPKEEPDC_02970 3.24e-114 yitZ - - G - - - Major Facilitator Superfamily
EPKEEPDC_02971 1.18e-251 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EPKEEPDC_02972 1.01e-292 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EPKEEPDC_02973 1.27e-175 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
EPKEEPDC_02974 5.65e-277 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
EPKEEPDC_02975 1.91e-261 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
EPKEEPDC_02976 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase ammonia chain
EPKEEPDC_02977 4.27e-225 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EPKEEPDC_02978 2.51e-39 yjzC - - S - - - YjzC-like protein
EPKEEPDC_02979 2.17e-23 yjzD - - S - - - Protein of unknown function (DUF2929)
EPKEEPDC_02980 2.42e-182 yjaU - - I - - - carboxylic ester hydrolase activity
EPKEEPDC_02981 5.84e-129 yjaV - - - - - - -
EPKEEPDC_02982 3.7e-234 med - - S ko:K05519,ko:K07335 - ko00000,ko03000 Transcriptional activator protein med
EPKEEPDC_02983 1.07e-35 comZ - - S ko:K02254 - ko00000,ko02044 ComZ
EPKEEPDC_02984 4.43e-30 yjzB - - - - - - -
EPKEEPDC_02985 1.61e-221 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EPKEEPDC_02986 3.06e-302 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
EPKEEPDC_02987 8.73e-189 yjaZ - - O - - - Zn-dependent protease
EPKEEPDC_02988 1.76e-233 appD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
EPKEEPDC_02989 1.2e-236 appF - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
EPKEEPDC_02990 0.0 appA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
EPKEEPDC_02991 6.73e-216 appB - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EPKEEPDC_02992 1.03e-208 appC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EPKEEPDC_02993 3.18e-190 yjbA - - S - - - Belongs to the UPF0736 family
EPKEEPDC_02994 6.15e-235 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
EPKEEPDC_02995 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
EPKEEPDC_02996 3.44e-211 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EPKEEPDC_02997 7.55e-212 oppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EPKEEPDC_02998 1.12e-248 oppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
EPKEEPDC_02999 1.27e-219 oppF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
EPKEEPDC_03000 1.36e-259 yjbB - - EGP - - - Major Facilitator Superfamily
EPKEEPDC_03001 8.88e-132 yjbC - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EPKEEPDC_03002 1.01e-87 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
EPKEEPDC_03003 1.43e-143 yjbE - - P - - - Integral membrane protein TerC family
EPKEEPDC_03004 4.65e-149 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
EPKEEPDC_03005 1.41e-278 coiA - - S ko:K06198 - ko00000 Competence protein
EPKEEPDC_03006 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
EPKEEPDC_03007 2.68e-28 - - - - - - - -
EPKEEPDC_03008 1.32e-218 yjbH - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
EPKEEPDC_03009 8.58e-94 yjbI - - S ko:K06886 - ko00000 Bacterial-like globin
EPKEEPDC_03010 2.8e-126 yjbJ - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
EPKEEPDC_03011 7.32e-130 yjbK - - S - - - protein conserved in bacteria
EPKEEPDC_03012 5.35e-81 yjbL - - S - - - Belongs to the UPF0738 family
EPKEEPDC_03013 5.06e-145 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 GTP pyrophosphokinase
EPKEEPDC_03014 2.94e-194 nadK 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EPKEEPDC_03015 1.49e-202 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
EPKEEPDC_03016 2.71e-179 prpE 3.1.3.16, 3.6.1.41 - T ko:K01090,ko:K01525 ko00230,map00230 ko00000,ko00001,ko01000 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
EPKEEPDC_03017 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
EPKEEPDC_03018 5.7e-177 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EPKEEPDC_03019 2.32e-138 tenI 5.3.99.10 - H ko:K10810 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Transcriptional regulator TenI
EPKEEPDC_03020 1.09e-275 thiO 1.4.3.19, 1.4.5.1 - E ko:K00285,ko:K03153 ko00360,ko00730,ko01100,map00360,map00730,map01100 ko00000,ko00001,ko01000 Glycine oxidase
EPKEEPDC_03021 2.18e-41 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 thiamine diphosphate biosynthetic process
EPKEEPDC_03022 6.78e-174 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
EPKEEPDC_03023 8.78e-238 thiF 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
EPKEEPDC_03024 8.38e-192 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
EPKEEPDC_03025 1.23e-182 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
EPKEEPDC_03026 9.24e-98 yjbX - - S - - - Spore coat protein
EPKEEPDC_03027 4.57e-108 cotZ - - S ko:K06344 - ko00000 Spore coat protein
EPKEEPDC_03028 3.12e-124 cotY - - S ko:K06343 - ko00000 Spore coat protein Z
EPKEEPDC_03029 5.55e-65 cotX - - S ko:K06342 - ko00000 Spore Coat Protein X and V domain
EPKEEPDC_03030 3.45e-26 cotW - - - ko:K06341 - ko00000 -
EPKEEPDC_03031 2.28e-53 cotV - - S ko:K06340 - ko00000 Spore Coat Protein X and V domain
EPKEEPDC_03032 5.88e-74 yjcA - - S - - - Protein of unknown function (DUF1360)
EPKEEPDC_03035 1.88e-52 spoVIF - - S - - - Stage VI sporulation protein F
EPKEEPDC_03036 0.0 yjcD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
EPKEEPDC_03037 6.31e-51 - - - - - - - -
EPKEEPDC_03038 7.75e-94 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EPKEEPDC_03039 9.9e-121 yjcG - - J - - - Belongs to the 2H phosphoesterase superfamily. YjcG family
EPKEEPDC_03040 1.57e-176 yjcH - - P ko:K07214 - ko00000 COG2382 Enterochelin esterase and related enzymes
EPKEEPDC_03041 1.98e-273 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
EPKEEPDC_03042 6.14e-279 metC 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
EPKEEPDC_03043 2.13e-129 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Alanine acetyltransferase
EPKEEPDC_03044 5.32e-267 yjcL - - S - - - Protein of unknown function (DUF819)
EPKEEPDC_03047 1.33e-50 - - - - - - - -
EPKEEPDC_03049 3.34e-295 - - - M - - - nucleic acid phosphodiester bond hydrolysis
EPKEEPDC_03053 3.54e-162 - - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
EPKEEPDC_03054 3.65e-61 yjcS - - S - - - Antibiotic biosynthesis monooxygenase
EPKEEPDC_03055 5.1e-60 yjcN - - - - - - -
EPKEEPDC_03056 0.0 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 transcriptional antiterminator
EPKEEPDC_03057 8.11e-151 manP 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EPKEEPDC_03058 1.99e-261 manP 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EPKEEPDC_03059 3.3e-236 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
EPKEEPDC_03060 9.24e-76 yjdF3 - - S - - - Protein of unknown function (DUF2992)
EPKEEPDC_03061 3.46e-115 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
EPKEEPDC_03063 3.38e-104 ebsC - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EPKEEPDC_03064 6.12e-40 - - - S - - - Domain of unknown function (DUF4177)
EPKEEPDC_03065 2.31e-69 yjdJ - - S - - - Domain of unknown function (DUF4306)
EPKEEPDC_03066 5.08e-222 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
EPKEEPDC_03068 0.0 yjeA 3.5.1.104 - G ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
EPKEEPDC_03069 2.22e-108 - - - S - - - Protein of unknown function (DUF2690)
EPKEEPDC_03070 1.13e-29 yjfB - - S - - - Putative motility protein
EPKEEPDC_03071 1.16e-212 yjfC - - O - - - Predicted Zn-dependent protease (DUF2268)
EPKEEPDC_03072 3.78e-45 yjgA - - T - - - Protein of unknown function (DUF2809)
EPKEEPDC_03073 4.96e-133 yjgB - - S - - - Domain of unknown function (DUF4309)
EPKEEPDC_03074 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
EPKEEPDC_03075 1.6e-122 yjgD - - S - - - Protein of unknown function (DUF1641)
EPKEEPDC_03077 1.69e-143 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
EPKEEPDC_03079 3.33e-286 yjiB 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
EPKEEPDC_03080 7.18e-279 yjiC - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
EPKEEPDC_03081 1.11e-41 - - - - - - - -
EPKEEPDC_03082 3.54e-188 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
EPKEEPDC_03083 9.04e-156 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
EPKEEPDC_03084 2.79e-175 yjkB - - P ko:K02068 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
EPKEEPDC_03085 1.81e-224 yjlA - - EG - - - Putative multidrug resistance efflux transporter
EPKEEPDC_03086 2.46e-118 yjlB - - S - - - Cupin domain
EPKEEPDC_03087 1.39e-87 yjlC - - S - - - Protein of unknown function (DUF1641)
EPKEEPDC_03088 2.15e-280 yjlD 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
EPKEEPDC_03089 0.0 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
EPKEEPDC_03090 4.34e-314 - - - G ko:K03292 - ko00000 symporter YjmB
EPKEEPDC_03091 2.08e-241 allD 1.1.1.350 - C ko:K00073 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000 Belongs to the LDH2 MDH2 oxidoreductase family
EPKEEPDC_03092 4.21e-242 yjmD 1.1.1.380 - E ko:K08322 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
EPKEEPDC_03093 2.18e-270 uxuA 4.2.1.8 - G ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of D-mannonate
EPKEEPDC_03094 2.23e-195 yjmF - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
EPKEEPDC_03095 3.93e-289 exuT - - G ko:K03535,ko:K08191 - ko00000,ko02000 Sugar (and other) transporter
EPKEEPDC_03096 9.87e-238 exuR - - K ko:K02529 - ko00000,ko03000 transcriptional
EPKEEPDC_03097 0.0 uxaB 1.1.1.58 - G ko:K00041 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 tagaturonate reductase activity
EPKEEPDC_03098 0.0 uxaA 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
EPKEEPDC_03099 9.2e-167 yjnA - - S ko:K07090 - ko00000 membrane transporter protein
EPKEEPDC_03100 2.71e-103 yjoA - - S - - - DinB family
EPKEEPDC_03101 5e-313 VCP - - O - - - AAA domain (dynein-related subfamily)
EPKEEPDC_03102 8.59e-272 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
EPKEEPDC_03104 1.79e-55 - - - S - - - YCII-related domain
EPKEEPDC_03105 7.58e-218 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
EPKEEPDC_03106 2.24e-79 yjqA - - S - - - Bacterial PH domain
EPKEEPDC_03107 1.58e-138 yjqB - - S - - - Pfam:DUF867
EPKEEPDC_03108 4.54e-204 yjqC - - P ko:K07217 - ko00000 Catalase
EPKEEPDC_03109 7.3e-143 xkdA - - E - - - IrrE N-terminal-like domain
EPKEEPDC_03110 2.01e-74 xre - - K - - - Helix-turn-helix XRE-family like proteins
EPKEEPDC_03112 4.36e-202 xkdB - - K - - - sequence-specific DNA binding
EPKEEPDC_03113 1.44e-150 xkdC - - L - - - Bacterial dnaA protein
EPKEEPDC_03117 8.12e-110 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
EPKEEPDC_03118 1.31e-176 xtmA - - L ko:K07474 - ko00000 phage terminase small subunit
EPKEEPDC_03119 0.0 xtmB - - S ko:K06909 - ko00000 phage terminase, large subunit
EPKEEPDC_03120 0.0 yqbA - - S - - - portal protein
EPKEEPDC_03121 9.88e-177 xkdF3 - - L - - - Putative phage serine protease XkdF
EPKEEPDC_03122 3.91e-217 xkdG - - S - - - Phage capsid family
EPKEEPDC_03123 4.68e-82 yqbG - - S - - - Protein of unknown function (DUF3199)
EPKEEPDC_03124 5.02e-84 yqbH - - S - - - Domain of unknown function (DUF3599)
EPKEEPDC_03125 9.69e-114 xkdI - - S - - - Bacteriophage HK97-gp10, putative tail-component
EPKEEPDC_03126 2.36e-100 xkdJ - - - - - - -
EPKEEPDC_03127 0.0 xkdK - - S - - - Phage tail sheath C-terminal domain
EPKEEPDC_03128 6.01e-99 xkdM - - S - - - Phage tail tube protein
EPKEEPDC_03129 9.21e-99 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
EPKEEPDC_03130 0.0 xkdO - - L - - - Transglycosylase SLT domain
EPKEEPDC_03131 1.48e-152 xkdP - - S - - - Lysin motif
EPKEEPDC_03132 2.31e-232 xkdQ - - G - - - NLP P60 protein
EPKEEPDC_03133 6.14e-53 xkdR - - S - - - Protein of unknown function (DUF2577)
EPKEEPDC_03134 5.43e-90 xkdS - - S - - - Protein of unknown function (DUF2634)
EPKEEPDC_03135 1.71e-241 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
EPKEEPDC_03136 3.23e-134 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
EPKEEPDC_03137 4.43e-56 - - - - - - - -
EPKEEPDC_03138 8.61e-228 - - - - - - - -
EPKEEPDC_03139 1.9e-68 xkdW - - S - - - XkdW protein
EPKEEPDC_03140 4.47e-31 xkdX - - - - - - -
EPKEEPDC_03141 4.85e-195 xepA - - - - - - -
EPKEEPDC_03142 2.21e-51 xhlA - - S - - - Haemolysin XhlA
EPKEEPDC_03143 1.15e-52 xhlB - - S - - - SPP1 phage holin
EPKEEPDC_03144 2.16e-207 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
EPKEEPDC_03145 1.78e-31 spoIISB - - S ko:K06389 - ko00000 Stage II sporulation protein SB
EPKEEPDC_03146 3.4e-175 spoIISA - - S ko:K06388 - ko00000 Toxin SpoIISA, type II toxin-antitoxin system
EPKEEPDC_03147 1.54e-225 pit - - P ko:K03306 - ko00000 phosphate transporter
EPKEEPDC_03148 1.85e-144 ykaA - - P ko:K07220 - ko00000 COG1392 Phosphate transport regulator (distant homolog of PhoU)
EPKEEPDC_03149 2.57e-309 steT - - E ko:K03294 - ko00000 amino acid
EPKEEPDC_03150 2.31e-232 ykcA - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
EPKEEPDC_03151 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EPKEEPDC_03152 2.21e-229 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
EPKEEPDC_03154 2.41e-284 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EPKEEPDC_03155 4.74e-178 proG 1.5.1.2 - E ko:K00286,ko:K02239 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko02044 Pyrroline-5-carboxylate reductase
EPKEEPDC_03156 3.85e-194 dppA - - E ko:K16203 - ko00000,ko01000,ko01002 D-aminopeptidase
EPKEEPDC_03157 9.7e-204 dppB - - P ko:K16200 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EPKEEPDC_03158 3.02e-224 dppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EPKEEPDC_03159 2.23e-235 dppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
EPKEEPDC_03160 0.0 dppE - - E ko:K16199 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
EPKEEPDC_03162 2.17e-221 ykfA 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
EPKEEPDC_03163 1.97e-256 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
EPKEEPDC_03164 9.9e-208 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
EPKEEPDC_03165 9.84e-236 ykfD - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
EPKEEPDC_03166 8.08e-261 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconolactonase
EPKEEPDC_03167 1.78e-205 ykgA - - E - - - Amidinotransferase
EPKEEPDC_03168 1.55e-119 ykhA - - I - - - Acyl-CoA hydrolase
EPKEEPDC_03169 2.54e-287 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EPKEEPDC_03170 2.11e-16 - - - - - - - -
EPKEEPDC_03171 3.95e-167 ykjA - - S - - - Protein of unknown function (DUF421)
EPKEEPDC_03172 6.42e-128 ykkA - - S - - - Protein of unknown function (DUF664)
EPKEEPDC_03173 2.43e-126 ykkB - - J - - - COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
EPKEEPDC_03174 1.27e-72 ykkC - - P ko:K18924 - ko00000,ko00002,ko02000 Multidrug resistance protein
EPKEEPDC_03175 1.36e-66 ykkD - - P ko:K18925 - ko00000,ko00002,ko02000 Multidrug resistance protein
EPKEEPDC_03176 1.66e-217 purU 3.5.1.10 - F ko:K01433 ko00630,ko00670,map00630,map00670 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
EPKEEPDC_03177 1.75e-254 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EPKEEPDC_03178 2.18e-287 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EPKEEPDC_03179 2.39e-93 ohrA - - O - - - Organic hydroperoxide resistance protein
EPKEEPDC_03180 1.42e-97 ohrR - - K - - - COG1846 Transcriptional regulators
EPKEEPDC_03181 2.34e-93 ohrB - - O - - - Organic hydroperoxide resistance protein
EPKEEPDC_03182 5.67e-115 guaD 3.5.4.3 - FJ ko:K01487 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 COG0590 Cytosine adenosine deaminases
EPKEEPDC_03183 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EPKEEPDC_03184 1.49e-225 isp - - O ko:K13275 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
EPKEEPDC_03185 3.99e-193 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
EPKEEPDC_03186 1.27e-173 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
EPKEEPDC_03187 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
EPKEEPDC_03188 1.39e-127 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
EPKEEPDC_03189 4.05e-141 ykoF - - S - - - YKOF-related Family
EPKEEPDC_03190 1.28e-160 ykoG - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EPKEEPDC_03191 1.89e-310 ykoH - - T - - - Histidine kinase
EPKEEPDC_03192 2.64e-143 ykoI - - S - - - Peptidase propeptide and YPEB domain
EPKEEPDC_03193 1.3e-111 ykoJ - - S - - - Peptidase propeptide and YPEB domain
EPKEEPDC_03194 1.45e-08 - - - - - - - -
EPKEEPDC_03196 9.86e-300 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
EPKEEPDC_03197 1.49e-70 tnrA - - K - - - transcriptional
EPKEEPDC_03198 3.3e-25 - - - - - - - -
EPKEEPDC_03199 3.04e-36 ykoL - - - - - - -
EPKEEPDC_03200 9.83e-106 ykoM - - K ko:K15973 - ko00000,ko03000 transcriptional
EPKEEPDC_03201 1.33e-278 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
EPKEEPDC_03202 2.48e-129 ykoP - - G - - - polysaccharide deacetylase
EPKEEPDC_03203 1.77e-197 ykoQ - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
EPKEEPDC_03204 0.0 ykoS - - - - - - -
EPKEEPDC_03205 1.35e-237 ykoT - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
EPKEEPDC_03206 0.0 ligD 6.5.1.1 - L ko:K01971 ko03450,map03450 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA ligase
EPKEEPDC_03207 5.1e-204 ku - - L ko:K10979 ko03450,map03450 ko00000,ko00001,ko03400 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
EPKEEPDC_03208 0.0 ykoW 2.7.7.65 - T ko:K21023 ko02025,map02025 ko00000,ko00001,ko01000 Diguanylate cyclase
EPKEEPDC_03209 1.71e-143 ykoX - - S - - - membrane-associated protein
EPKEEPDC_03210 4.63e-227 ykoY - - P - - - COG0861 Membrane protein TerC, possibly involved in tellurium resistance
EPKEEPDC_03211 1.8e-167 sigI - - K ko:K03093 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EPKEEPDC_03212 9.93e-200 rsgI - - S - - - Anti-sigma factor N-terminus
EPKEEPDC_03213 1.4e-36 sspD - - S ko:K06421 - ko00000 small acid-soluble spore protein
EPKEEPDC_03214 1.55e-159 ykrK - - S - - - Domain of unknown function (DUF1836)
EPKEEPDC_03215 3.97e-199 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
EPKEEPDC_03216 2.58e-310 ktrD - - P - - - COG0168 Trk-type K transport systems, membrane components
EPKEEPDC_03218 1.77e-28 ykzE - - - - - - -
EPKEEPDC_03219 3.34e-244 ykrP - - G - - - COG3594 Fucose 4-O-acetylase and related acetyltransferases
EPKEEPDC_03220 0.0 kinE 2.7.13.3 - T ko:K13533 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EPKEEPDC_03221 2.76e-115 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EPKEEPDC_03223 4.63e-253 mtnA 5.3.1.23 - E ko:K08963 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EPKEEPDC_03224 4.98e-293 mtnK 2.7.1.100 - F ko:K00899 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
EPKEEPDC_03225 5.71e-193 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
EPKEEPDC_03226 2.78e-295 mtnE - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
EPKEEPDC_03227 9.72e-295 mtnW 5.3.2.5 - G ko:K08965 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
EPKEEPDC_03228 1.77e-175 mtnX 3.1.3.87 - E ko:K08966 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
EPKEEPDC_03229 3.71e-146 mtnB 4.2.1.109 - E ko:K08964 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
EPKEEPDC_03230 3.03e-123 mtnD 1.13.11.53, 1.13.11.54 - S ko:K08967 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EPKEEPDC_03231 8.82e-68 - - - S - - - Protein of unknown function (DUF1232)
EPKEEPDC_03233 5.84e-95 eag - - - - - - -
EPKEEPDC_03234 0.0 kinD 2.7.13.3 - T ko:K13532 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
EPKEEPDC_03235 5.17e-99 ykvE - - K ko:K15973 - ko00000,ko03000 transcriptional
EPKEEPDC_03236 4.91e-170 motB - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
EPKEEPDC_03237 3.23e-178 motA - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
EPKEEPDC_03238 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
EPKEEPDC_03239 2.02e-228 ykvI - - S - - - membrane
EPKEEPDC_03240 6.42e-161 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EPKEEPDC_03241 6.96e-105 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
EPKEEPDC_03242 3.56e-179 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
EPKEEPDC_03243 2.36e-125 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EPKEEPDC_03244 2.8e-81 ykvN - - K - - - Transcriptional regulator
EPKEEPDC_03245 9.35e-173 ykvO - - IQ - - - Enoyl-(Acyl carrier protein) reductase
EPKEEPDC_03246 3.01e-272 - - - M - - - Glycosyl transferases group 1
EPKEEPDC_03247 7.56e-48 - 3.5.1.104 - M ko:K22278 - ko00000,ko01000 LysM domain
EPKEEPDC_03248 4.11e-203 - - - G - - - Glycosyl hydrolases family 18
EPKEEPDC_03249 8.95e-61 ykvR - - S - - - Protein of unknown function (DUF3219)
EPKEEPDC_03250 5.43e-35 ykvS - - S - - - protein conserved in bacteria
EPKEEPDC_03251 2.5e-39 - - - - - - - -
EPKEEPDC_03252 9.09e-142 ykvT 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell Wall Hydrolase
EPKEEPDC_03253 3.74e-301 ykvU - - S - - - COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EPKEEPDC_03254 2.76e-115 stoA - - CO - - - thiol-disulfide
EPKEEPDC_03255 0.0 zosA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
EPKEEPDC_03256 3.99e-09 - - - - - - - -
EPKEEPDC_03257 3.73e-262 ykvY 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
EPKEEPDC_03258 5.43e-229 ykvZ - - K - - - Transcriptional regulator
EPKEEPDC_03260 1.14e-166 glcT - - K ko:K03480,ko:K03488 - ko00000,ko03000 antiterminator
EPKEEPDC_03261 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EPKEEPDC_03262 1.51e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPr
EPKEEPDC_03263 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EPKEEPDC_03264 1.54e-51 splA - - S ko:K06315 - ko00000,ko03000 Transcriptional regulator
EPKEEPDC_03265 2.49e-256 splB 4.1.99.14 - L ko:K03716 - ko00000,ko01000 Spore photoproduct lyase
EPKEEPDC_03266 2.53e-161 ykwB - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EPKEEPDC_03267 0.0 mcpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
EPKEEPDC_03268 4.02e-203 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
EPKEEPDC_03269 6.8e-18 vgb - - H ko:K18235 - ko00000,ko01000,ko01504 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid
EPKEEPDC_03270 4.4e-171 ykwD - - J - - - protein with SCP PR1 domains
EPKEEPDC_03271 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
EPKEEPDC_03272 0.0 kinA 2.7.13.3 - T ko:K02491 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EPKEEPDC_03273 1.46e-283 patA - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
EPKEEPDC_03274 1.05e-22 - - - - - - - -
EPKEEPDC_03275 4.95e-216 cheV - - T ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 Chemotaxis protein CheV
EPKEEPDC_03276 3.71e-110 ykyB - - S - - - YkyB-like protein
EPKEEPDC_03277 2.55e-305 ykuC - - EGP - - - COG0477 Permeases of the major facilitator superfamily
EPKEEPDC_03278 5.84e-115 ykuD - - S - - - protein conserved in bacteria
EPKEEPDC_03279 3.48e-212 ykuE - - S ko:K07098 - ko00000 Metallophosphoesterase
EPKEEPDC_03280 2.6e-182 fadH 1.3.1.34 - IQ ko:K00219 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EPKEEPDC_03281 1.76e-298 ykuI - - T - - - Diguanylate phosphodiesterase
EPKEEPDC_03282 5.16e-50 ykuJ - - S - - - protein conserved in bacteria
EPKEEPDC_03283 3.73e-121 - - - S ko:K09776 - ko00000 Ribonuclease H-like
EPKEEPDC_03284 7.83e-38 ykzF - - S - - - Antirepressor AbbA
EPKEEPDC_03285 5.15e-100 ykuL - - S - - - CBS domain
EPKEEPDC_03286 6.52e-216 ccpC - - K - - - Transcriptional regulator
EPKEEPDC_03287 1.44e-109 - - - C ko:K03839 - ko00000 Flavodoxin domain
EPKEEPDC_03288 6.07e-223 ykuO - - - - - - -
EPKEEPDC_03289 1.03e-101 fld - - C ko:K03839 - ko00000 Flavodoxin
EPKEEPDC_03290 1.31e-125 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
EPKEEPDC_03291 7.35e-272 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
EPKEEPDC_03292 7.23e-51 ykuS - - S - - - Belongs to the UPF0180 family
EPKEEPDC_03293 4.1e-181 ykuT - - M ko:K22044 - ko00000,ko02000 Mechanosensitive ion channel
EPKEEPDC_03294 9.78e-130 ykuU - - O - - - Alkyl hydroperoxide reductase
EPKEEPDC_03295 6.01e-104 ykuV - - CO - - - thiol-disulfide
EPKEEPDC_03296 1.78e-120 rok - - K - - - Repressor of ComK
EPKEEPDC_03297 8.12e-199 yknT - - - ko:K06437 - ko00000 -
EPKEEPDC_03298 3.75e-141 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
EPKEEPDC_03299 7.59e-245 moeB 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
EPKEEPDC_03300 2.04e-311 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 molybdopterin
EPKEEPDC_03301 8.11e-121 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
EPKEEPDC_03302 1.1e-108 moaE 2.8.1.12 - H ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 COG0314 Molybdopterin converting factor, large subunit
EPKEEPDC_03303 2.82e-44 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EPKEEPDC_03304 0.0 yknU - - V ko:K06147,ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
EPKEEPDC_03305 0.0 yknV - - V ko:K02021,ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
EPKEEPDC_03306 1.08e-149 yknW - - S - - - Yip1 domain
EPKEEPDC_03307 1.5e-229 yknX - - M ko:K02005,ko:K13888 - ko00000,ko00002,ko02000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EPKEEPDC_03308 7.12e-159 yknY - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EPKEEPDC_03309 6.71e-266 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
EPKEEPDC_03310 7.41e-176 fruR - - K ko:K03436 - ko00000,ko03000 Transcriptional regulator
EPKEEPDC_03311 2.35e-214 pfkB 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
EPKEEPDC_03312 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
EPKEEPDC_03313 1.42e-133 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
EPKEEPDC_03314 7.71e-52 ykoA - - - - - - -
EPKEEPDC_03315 0.0 ykpA - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
EPKEEPDC_03316 2.75e-213 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EPKEEPDC_03317 2.07e-303 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
EPKEEPDC_03318 1.09e-18 - - - S - - - Uncharacterized protein YkpC
EPKEEPDC_03319 6.17e-234 mreBH - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod-share determining protein MreBH
EPKEEPDC_03320 2.63e-58 abrB - - K ko:K06284 - ko00000,ko03000 of stationary sporulation gene expression
EPKEEPDC_03321 4.4e-305 kinC 2.7.13.3 - T ko:K07698 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
EPKEEPDC_03322 1.7e-198 ykqA - - P - - - Gamma-glutamyl cyclotransferase, AIG2-like
EPKEEPDC_03323 1.68e-148 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
EPKEEPDC_03324 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EPKEEPDC_03325 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EPKEEPDC_03326 8.98e-42 ykzG - - S - - - Belongs to the UPF0356 family
EPKEEPDC_03327 1.18e-186 ykrA - - S - - - hydrolases of the HAD superfamily
EPKEEPDC_03328 3.96e-131 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
EPKEEPDC_03329 1.26e-07 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
EPKEEPDC_03330 1.06e-138 ykyA - - L - - - Putative cell-wall binding lipoprotein
EPKEEPDC_03331 1.06e-258 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
EPKEEPDC_03332 3.52e-227 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
EPKEEPDC_03333 1.47e-301 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
EPKEEPDC_03334 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
EPKEEPDC_03335 4.55e-83 slp - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
EPKEEPDC_03336 0.0 speA 4.1.1.17, 4.1.1.19 - E ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Arginine
EPKEEPDC_03337 6.37e-55 yktA - - S - - - Belongs to the UPF0223 family
EPKEEPDC_03338 2.15e-151 yktB - - S - - - Belongs to the UPF0637 family
EPKEEPDC_03339 4.48e-35 ykzI - - - - - - -
EPKEEPDC_03340 2.61e-192 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase
EPKEEPDC_03341 5.78e-98 ykzC - - S - - - Acetyltransferase (GNAT) family
EPKEEPDC_03342 4.98e-221 - - - Q - - - Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EPKEEPDC_03343 0.0 mpl 3.4.24.28, 3.4.24.29 - E ko:K01400,ko:K01401,ko:K19351 ko01503,ko05150,map01503,map05150 ko00000,ko00001,ko01000,ko01002 Peptidase M4
EPKEEPDC_03344 0.0 ylaA - - - - - - -
EPKEEPDC_03345 4.12e-56 ylaB - - - - - - -
EPKEEPDC_03346 1.69e-113 ylaC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
EPKEEPDC_03348 2.3e-55 ylaE - - - - - - -
EPKEEPDC_03349 2.21e-30 - - - S - - - Family of unknown function (DUF5325)
EPKEEPDC_03350 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
EPKEEPDC_03351 4.4e-63 ylaH - - S - - - YlaH-like protein
EPKEEPDC_03352 3.64e-43 ylaI - - S - - - protein conserved in bacteria
EPKEEPDC_03353 2.97e-127 ylaJ - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
EPKEEPDC_03354 5.64e-315 ylaK - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
EPKEEPDC_03355 9.32e-112 ylaL - - S - - - Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EPKEEPDC_03356 3.49e-219 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
EPKEEPDC_03357 6.94e-59 ylaN - - S - - - Belongs to the UPF0358 family
EPKEEPDC_03358 7.05e-271 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
EPKEEPDC_03359 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EPKEEPDC_03360 2.85e-212 ctaA - - O ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 ko00000,ko00001,ko00002,ko03029 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
EPKEEPDC_03361 1.7e-208 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
EPKEEPDC_03362 2.38e-252 ctaC 1.9.3.1 - C ko:K02275 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
EPKEEPDC_03363 0.0 ctaD 1.9.3.1 - C ko:K02274 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EPKEEPDC_03364 1.84e-145 ctaE 1.9.3.1 - C ko:K02276 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
EPKEEPDC_03365 6.09e-70 ctaF 1.9.3.1 - C ko:K02277 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
EPKEEPDC_03366 1.21e-213 ctaG - - S ko:K02862 - ko00000 cytochrome c oxidase
EPKEEPDC_03367 1.61e-81 ylbA - - S - - - YugN-like family
EPKEEPDC_03368 1.08e-97 ylbB - - T - - - COG0517 FOG CBS domain
EPKEEPDC_03369 2.44e-253 ylbC - - S - - - protein with SCP PR1 domains
EPKEEPDC_03370 9.28e-89 ylbD - - S - - - Putative coat protein
EPKEEPDC_03371 1.73e-48 ylbE - - S - - - YlbE-like protein
EPKEEPDC_03372 2.34e-97 ylbF - - S - - - Belongs to the UPF0342 family
EPKEEPDC_03373 4.36e-52 ylbG - - S - - - UPF0298 protein
EPKEEPDC_03374 2.47e-125 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
EPKEEPDC_03375 1.55e-110 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EPKEEPDC_03376 9.11e-281 ylbJ - - S - - - Sporulation integral membrane protein YlbJ
EPKEEPDC_03377 2.56e-176 ylbK - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
EPKEEPDC_03378 7.81e-239 ylbL - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
EPKEEPDC_03379 8.29e-292 ylbM - - S - - - Belongs to the UPF0348 family
EPKEEPDC_03381 6.94e-117 ylbN - - S ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
EPKEEPDC_03382 1.71e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
EPKEEPDC_03383 4.72e-107 ylbO - - S ko:K06314 - ko00000,ko03000 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
EPKEEPDC_03384 1.33e-115 ylbP - - K - - - n-acetyltransferase
EPKEEPDC_03385 3.6e-211 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EPKEEPDC_03386 0.0 bshC - - S ko:K22136 - ko00000 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
EPKEEPDC_03387 9.82e-102 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
EPKEEPDC_03388 1.66e-218 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
EPKEEPDC_03389 3.42e-68 ftsL - - D - - - Essential cell division protein
EPKEEPDC_03390 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
EPKEEPDC_03391 0.0 spoVD - - M ko:K08384 ko00550,map00550 ko00000,ko00001,ko01011 stage V sporulation protein D
EPKEEPDC_03392 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EPKEEPDC_03393 9.59e-220 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EPKEEPDC_03394 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EPKEEPDC_03395 6.64e-237 spoVE - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
EPKEEPDC_03396 1.28e-255 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EPKEEPDC_03397 3.74e-211 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
EPKEEPDC_03398 3.37e-178 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
EPKEEPDC_03399 2.23e-142 ylxW - - S - - - protein conserved in bacteria
EPKEEPDC_03400 4.89e-122 ylxX - - S - - - protein conserved in bacteria
EPKEEPDC_03401 5.37e-76 sbp - - S - - - small basic protein
EPKEEPDC_03402 4.88e-299 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
EPKEEPDC_03403 1.84e-260 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EPKEEPDC_03404 0.0 bpr - - O ko:K13276 - ko00000,ko01000,ko01002,ko03110 COG1404 Subtilisin-like serine proteases
EPKEEPDC_03405 2.77e-60 spoIIGA - - M ko:K06383 - ko00000,ko01000,ko01002 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
EPKEEPDC_03406 1.28e-140 spoIIGA - - M ko:K06383 - ko00000,ko01000,ko01002 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
EPKEEPDC_03407 1.48e-160 sigE - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EPKEEPDC_03408 7.99e-180 sigG - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EPKEEPDC_03409 1.83e-187 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
EPKEEPDC_03410 0.0 argE - - E ko:K20895 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Acetylornithine deacetylase
EPKEEPDC_03411 3.58e-51 ylmC - - S - - - sporulation protein
EPKEEPDC_03412 9.17e-204 ylmD - - S ko:K05810 - ko00000,ko01000 Belongs to the multicopper oxidase YfiH RL5 family
EPKEEPDC_03413 9.03e-162 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EPKEEPDC_03414 1.28e-86 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
EPKEEPDC_03415 1.22e-53 ylmG - - S ko:K02221 - ko00000,ko02044 membrane
EPKEEPDC_03416 1.49e-178 ylmH - - S - - - conserved protein, contains S4-like domain
EPKEEPDC_03417 6.44e-100 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
EPKEEPDC_03418 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EPKEEPDC_03419 3.74e-82 ylyA - - T - - - COG1734 DnaK suppressor protein
EPKEEPDC_03420 2.71e-103 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EPKEEPDC_03421 3.52e-225 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
EPKEEPDC_03422 4.45e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EPKEEPDC_03423 6.55e-292 pyrP - - F ko:K02824 - ko00000,ko02000 Xanthine uracil
EPKEEPDC_03424 1.72e-212 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
EPKEEPDC_03425 9.71e-317 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
EPKEEPDC_03426 1.31e-269 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
EPKEEPDC_03427 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarB family
EPKEEPDC_03428 1.75e-181 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
EPKEEPDC_03429 4.26e-221 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
EPKEEPDC_03430 6.56e-164 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
EPKEEPDC_03431 8.96e-149 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EPKEEPDC_03433 3.44e-181 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
EPKEEPDC_03434 4.05e-227 cysP - - P ko:K16331 - ko00000,ko02000 phosphate transporter
EPKEEPDC_03435 8.77e-284 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
EPKEEPDC_03436 1.59e-141 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
EPKEEPDC_03437 5.9e-185 cobA 2.1.1.107 - H ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
EPKEEPDC_03438 5.9e-187 sirB 4.99.1.4 - S ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sirohydrochlorin ferrochelatase
EPKEEPDC_03439 4.41e-106 sirC 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Siroheme synthase
EPKEEPDC_03440 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
EPKEEPDC_03441 0.0 yloB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 COG0474 Cation transport ATPase
EPKEEPDC_03442 8.41e-202 yloC - - S - - - stress-induced protein
EPKEEPDC_03443 3.97e-54 ylzA - - S ko:K09777 - ko00000 Belongs to the UPF0296 family
EPKEEPDC_03444 5.73e-143 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
EPKEEPDC_03445 6.21e-39 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
EPKEEPDC_03446 5.13e-286 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EPKEEPDC_03447 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EPKEEPDC_03448 4.8e-109 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
EPKEEPDC_03449 7.08e-223 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EPKEEPDC_03450 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EPKEEPDC_03451 8.79e-263 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
EPKEEPDC_03452 2.05e-179 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
EPKEEPDC_03453 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
EPKEEPDC_03454 1.12e-214 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
EPKEEPDC_03455 9.44e-153 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
EPKEEPDC_03456 1.35e-155 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
EPKEEPDC_03457 7.06e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
EPKEEPDC_03458 3.65e-78 yloU - - S - - - protein conserved in bacteria
EPKEEPDC_03459 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
EPKEEPDC_03460 5.89e-153 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
EPKEEPDC_03461 1.19e-201 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
EPKEEPDC_03462 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EPKEEPDC_03463 6.22e-121 fapR - - K - - - Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
EPKEEPDC_03464 8.33e-230 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
EPKEEPDC_03465 1.86e-218 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
EPKEEPDC_03466 3.5e-167 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
EPKEEPDC_03467 1.15e-43 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
EPKEEPDC_03468 2.12e-174 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
EPKEEPDC_03469 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
EPKEEPDC_03470 3.38e-227 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
EPKEEPDC_03471 1.67e-114 - - - - - - - -
EPKEEPDC_03472 5.64e-66 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
EPKEEPDC_03473 3.95e-308 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EPKEEPDC_03474 1.13e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
EPKEEPDC_03475 1.2e-49 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
EPKEEPDC_03476 9.77e-80 ylqD - - S - - - YlqD protein
EPKEEPDC_03477 7.5e-122 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EPKEEPDC_03478 2.41e-177 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
EPKEEPDC_03479 8.14e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
EPKEEPDC_03480 1.4e-200 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EPKEEPDC_03481 5.83e-175 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EPKEEPDC_03482 0.0 ylqG - - - - - - -
EPKEEPDC_03483 1.7e-59 ylqH - - S ko:K04061 - ko00000,ko02044 homolog of the cytoplasmic domain of flagellar protein FhlB
EPKEEPDC_03484 6.77e-269 sucC 6.2.1.5 - C ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
EPKEEPDC_03485 3.09e-213 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EPKEEPDC_03486 3.62e-215 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
EPKEEPDC_03487 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EPKEEPDC_03488 2.22e-313 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EPKEEPDC_03489 1.13e-217 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 tyrosine recombinase XerC
EPKEEPDC_03490 3.01e-120 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EPKEEPDC_03491 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EPKEEPDC_03492 1.95e-175 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EPKEEPDC_03493 1.62e-83 flgB - - N ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
EPKEEPDC_03494 1.46e-96 flgC - - N ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the flagella basal body rod proteins family
EPKEEPDC_03495 5.5e-53 fliE - - N ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-basal body
EPKEEPDC_03496 0.0 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
EPKEEPDC_03497 6.08e-230 fliG - - N ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
EPKEEPDC_03498 7.8e-144 fliH - - NU ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 COG1317 Flagellar biosynthesis type III secretory pathway protein
EPKEEPDC_03499 3.5e-307 fliI 3.6.3.14 - NU ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 COG1157 Flagellar biosynthesis type III secretory pathway ATPase
EPKEEPDC_03500 1.79e-91 fliJ - - N ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar biosynthesis chaperone
EPKEEPDC_03501 6.64e-10 ylxF - - S - - - MgtE intracellular N domain
EPKEEPDC_03502 2.36e-32 ylxF - - S - - - MgtE intracellular N domain
EPKEEPDC_03503 3.04e-303 fliK - - N ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-length control protein
EPKEEPDC_03504 2.81e-96 flgD - - N ko:K02389 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod modification protein
EPKEEPDC_03505 1.66e-174 flgG - - N ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod
EPKEEPDC_03506 5.59e-78 fliL - - N ko:K02415 - ko00000,ko02035 Controls the rotational direction of flagella during chemotaxis
EPKEEPDC_03507 6.61e-231 fliM - - N ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
EPKEEPDC_03508 1.38e-253 fliY - - N ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EPKEEPDC_03509 1.22e-76 cheY - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 response regulator
EPKEEPDC_03510 3.07e-134 fliZ - - N ko:K02418 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthesis protein, FliO
EPKEEPDC_03511 1.21e-141 fliP - - N ko:K02419 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Plays a role in the flagellum-specific transport system
EPKEEPDC_03512 2.13e-49 fliQ - - N ko:K02420 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Role in flagellar biosynthesis
EPKEEPDC_03513 1.47e-170 fliR - - N ko:K02421 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthetic protein FliR
EPKEEPDC_03514 3.89e-244 flhB - - N ko:K02401 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EPKEEPDC_03515 0.0 flhA - - N ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EPKEEPDC_03516 9.37e-255 flhF - - N ko:K02404 - ko00000,ko02035 Flagellar biosynthesis regulator FlhF
EPKEEPDC_03517 6.33e-200 ylxH - - D ko:K04562 - ko00000,ko02035 Belongs to the ParA family
EPKEEPDC_03518 2.58e-252 cheB 3.1.1.61, 3.5.1.44 - NT ko:K03412 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
EPKEEPDC_03519 0.0 cheA 2.7.13.3 - NT ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 COG0643 Chemotaxis protein histidine kinase and related kinases
EPKEEPDC_03520 1.56e-103 cheW - - NT ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 COG0835 Chemotaxis signal transduction protein
EPKEEPDC_03521 5.06e-144 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
EPKEEPDC_03522 3.34e-112 cheD 3.5.1.44 - NT ko:K03411 ko02030,map02030 ko00000,ko00001,ko01000,ko02035 Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
EPKEEPDC_03523 1.33e-175 sigD - - K ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EPKEEPDC_03524 4e-100 ylxL - - - - - - -
EPKEEPDC_03525 1.49e-168 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
EPKEEPDC_03526 9.82e-202 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EPKEEPDC_03527 5.82e-163 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
EPKEEPDC_03528 9.6e-119 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
EPKEEPDC_03529 3.84e-187 uppS 2.5.1.31 - I ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EPKEEPDC_03530 5.77e-179 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
EPKEEPDC_03531 1.39e-276 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
EPKEEPDC_03532 6.84e-294 rasP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
EPKEEPDC_03533 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
EPKEEPDC_03534 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EPKEEPDC_03535 1.34e-104 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
EPKEEPDC_03536 5.49e-261 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
EPKEEPDC_03537 2.01e-57 ylxR - - K ko:K07742 - ko00000 nucleic-acid-binding protein implicated in transcription termination
EPKEEPDC_03538 6.16e-63 ylxQ - - J - - - ribosomal protein
EPKEEPDC_03539 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EPKEEPDC_03540 1.11e-59 ylxP - - S ko:K09764 - ko00000 protein conserved in bacteria
EPKEEPDC_03541 3.29e-75 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EPKEEPDC_03542 6.04e-220 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EPKEEPDC_03543 4.48e-230 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
EPKEEPDC_03544 7.11e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EPKEEPDC_03545 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
EPKEEPDC_03546 7.18e-233 ylxY - - G - - - Sporulation protein, polysaccharide deacetylase
EPKEEPDC_03547 1.62e-295 mlpA - - S - - - Belongs to the peptidase M16 family
EPKEEPDC_03548 1.53e-56 ymxH - - S - - - YlmC YmxH family
EPKEEPDC_03549 5.3e-208 dpaA - - CH ko:K06410 - ko00000 Dipicolinate synthase subunit A
EPKEEPDC_03550 4.73e-140 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
EPKEEPDC_03551 2.36e-247 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EPKEEPDC_03552 4.9e-283 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
EPKEEPDC_03553 6.39e-201 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EPKEEPDC_03554 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EPKEEPDC_03555 8.69e-78 tepA - - OU - - - COG0740 Protease subunit of ATP-dependent Clp proteases
EPKEEPDC_03556 7.6e-65 tepA - - OU - - - COG0740 Protease subunit of ATP-dependent Clp proteases
EPKEEPDC_03557 4.94e-44 - - - S - - - YlzJ-like protein
EPKEEPDC_03558 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
EPKEEPDC_03559 1.28e-171 ymfC - - K ko:K03710 - ko00000,ko03000 Transcriptional regulator
EPKEEPDC_03560 5.1e-266 ymfD - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
EPKEEPDC_03561 1.1e-297 albE - - S - - - Peptidase M16
EPKEEPDC_03562 2.77e-308 ymfH - - S - - - zinc protease
EPKEEPDC_03563 3.01e-166 ymfI 1.1.1.100 - S ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
EPKEEPDC_03564 5.13e-55 ymfJ - - S - - - Protein of unknown function (DUF3243)
EPKEEPDC_03565 3.91e-183 ymfK - - S - - - Protein of unknown function (DUF3388)
EPKEEPDC_03566 8.75e-177 ymfM - - S ko:K15539 - ko00000 protein conserved in bacteria
EPKEEPDC_03567 3.34e-132 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EPKEEPDC_03568 1.76e-298 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
EPKEEPDC_03569 4.7e-239 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EPKEEPDC_03570 6.36e-277 pbpX - - V - - - Beta-lactamase
EPKEEPDC_03571 4.25e-306 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
EPKEEPDC_03572 6.18e-195 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 protein conserved in bacteria
EPKEEPDC_03573 2.44e-49 spoVS - - S ko:K06416 - ko00000 Stage V sporulation protein S
EPKEEPDC_03574 1.38e-251 tdh 1.1.1.103 - C ko:K00060 ko00260,map00260 ko00000,ko00001,ko01000 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
EPKEEPDC_03575 1.69e-277 kbl 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
EPKEEPDC_03576 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EPKEEPDC_03577 1.27e-89 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
EPKEEPDC_03578 1.74e-119 cotE - - S ko:K06328 - ko00000 Spore coat protein
EPKEEPDC_03579 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EPKEEPDC_03580 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EPKEEPDC_03581 6.68e-92 - - - S - - - Regulatory protein YrvL
EPKEEPDC_03582 3.24e-126 ymcC - - S - - - Membrane
EPKEEPDC_03583 6.31e-142 pksA - - K - - - Transcriptional regulator
EPKEEPDC_03584 4.02e-167 pksB 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 Polyketide biosynthesis
EPKEEPDC_03585 4.37e-207 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
EPKEEPDC_03587 1.4e-237 pksD - - Q ko:K15328 - ko00000,ko01008 Acyl transferase domain
EPKEEPDC_03588 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
EPKEEPDC_03589 5.46e-51 acpK - - IQ ko:K15337 - ko00000,ko01008 Phosphopantetheine attachment site
EPKEEPDC_03590 3.58e-302 - 2.3.1.179 - I ko:K00646,ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
EPKEEPDC_03591 6.55e-312 pksG 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
EPKEEPDC_03592 2.29e-180 - - - I ko:K15312 - ko00000,ko01008 enoyl-CoA hydratase
EPKEEPDC_03593 1.56e-176 pksI - - I ko:K15313 - ko00000,ko01008 Belongs to the enoyl-CoA hydratase isomerase family
EPKEEPDC_03594 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
EPKEEPDC_03595 0.0 - - - Q ko:K13612 - ko00000,ko01004,ko01008 Polyketide synthase of type I
EPKEEPDC_03596 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
EPKEEPDC_03597 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
EPKEEPDC_03598 0.0 - - - HQ ko:K13615 - ko00000,ko01004,ko01008 Beta-ketoacyl synthase
EPKEEPDC_03599 1.13e-293 cypA 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
EPKEEPDC_03600 8.03e-81 ymzB - - - - - - -
EPKEEPDC_03601 8.93e-206 - - - S - - - Metallo-beta-lactamase superfamily
EPKEEPDC_03602 0.0 aprX - - O ko:K17734 - ko00000,ko01000,ko01002 Belongs to the peptidase S8 family
EPKEEPDC_03604 3.96e-163 ymaC - - S - - - Replication protein
EPKEEPDC_03605 2.44e-104 ymaD - - O - - - redox protein, regulator of disulfide bond formation
EPKEEPDC_03606 1.57e-73 ebrB - - P ko:K03297,ko:K11814,ko:K11815 - ko00000,ko00002,ko02000 COG2076 Membrane transporters of cations and cationic drugs
EPKEEPDC_03607 2.02e-66 ebrA - - P ko:K11814 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
EPKEEPDC_03609 5.41e-76 ymaF - - S - - - YmaF family
EPKEEPDC_03610 1.38e-223 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EPKEEPDC_03611 1.28e-45 hfq - - J ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
EPKEEPDC_03612 1.63e-31 - - - - - - - -
EPKEEPDC_03613 1.2e-30 ymzA - - - - - - -
EPKEEPDC_03614 5.01e-66 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
EPKEEPDC_03615 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EPKEEPDC_03616 1.65e-243 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EPKEEPDC_03617 1.51e-139 - - - - - - - -
EPKEEPDC_03618 3.32e-149 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
EPKEEPDC_03619 2.29e-226 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
EPKEEPDC_03620 1.82e-293 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EPKEEPDC_03621 4.78e-310 ynbB - - P - - - COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
EPKEEPDC_03622 4.05e-89 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 transcriptional
EPKEEPDC_03623 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
EPKEEPDC_03624 1.61e-173 - - - L - - - Belongs to the 'phage' integrase family
EPKEEPDC_03627 4.77e-07 - - - K - - - Cro/C1-type HTH DNA-binding domain
EPKEEPDC_03628 1.68e-07 - - - K - - - Helix-turn-helix domain
EPKEEPDC_03633 5.46e-94 - - - L - - - Conserved phage C-terminus (Phg_2220_C)
EPKEEPDC_03634 1.84e-20 - - - L ko:K02315 - ko00000,ko03032 IstB-like ATP binding protein
EPKEEPDC_03639 2.78e-08 - - - - - - - -
EPKEEPDC_03645 7.92e-68 - - - M - - - ArpU family transcriptional regulator
EPKEEPDC_03646 9.22e-94 - - - L - - - Phage integrase family
EPKEEPDC_03647 1.9e-08 - - - - - - - -
EPKEEPDC_03650 5.31e-82 - - - S - - - HNH endonuclease
EPKEEPDC_03651 1.39e-25 - - - - - - - -
EPKEEPDC_03652 4.07e-89 - - - S - - - Phage terminase, small subunit
EPKEEPDC_03653 2.05e-279 - - - S - - - Phage Terminase
EPKEEPDC_03654 1.28e-14 - - - - - - - -
EPKEEPDC_03655 3.21e-271 - - - S - - - Phage portal protein
EPKEEPDC_03656 1.33e-134 - - - S - - - peptidase activity
EPKEEPDC_03657 5.11e-229 - - - S - - - capsid protein
EPKEEPDC_03658 1.57e-08 - - - S - - - peptidoglycan catabolic process
EPKEEPDC_03659 1.73e-38 - - - S - - - peptidoglycan catabolic process
EPKEEPDC_03660 7.45e-34 - - - S - - - Phage gp6-like head-tail connector protein
EPKEEPDC_03661 8.29e-19 - - - S - - - Phage head-tail joining protein
EPKEEPDC_03662 3.77e-63 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
EPKEEPDC_03663 4.06e-40 - - - - - - - -
EPKEEPDC_03664 9.75e-79 - - - - - - - -
EPKEEPDC_03665 9.94e-35 - - - - - - - -
EPKEEPDC_03666 4.09e-16 - - - - - - - -
EPKEEPDC_03667 0.0 - - - S - - - peptidoglycan catabolic process
EPKEEPDC_03668 4.84e-142 - - - S - - - Phage tail protein
EPKEEPDC_03669 3.26e-307 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Prophage endopeptidase tail
EPKEEPDC_03670 1.37e-61 - - - - - - - -
EPKEEPDC_03673 2.13e-64 - - - S - - - Domain of unknown function (DUF2479)
EPKEEPDC_03676 1.32e-76 - - - S - - - Bacteriophage holin family
EPKEEPDC_03677 2.43e-167 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
EPKEEPDC_03678 4.02e-109 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
EPKEEPDC_03679 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
EPKEEPDC_03681 4.94e-13 - - - - - - - -
EPKEEPDC_03685 7.88e-119 - - - M - - - Glycosyltransferase like family
EPKEEPDC_03686 5.8e-156 - - - H - - - Methionine biosynthesis protein MetW
EPKEEPDC_03687 2.03e-246 - - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
EPKEEPDC_03688 3.14e-274 - - - H - - - N-terminal domain of galactosyltransferase
EPKEEPDC_03690 9.87e-123 ynaD - - J - - - Acetyltransferase (GNAT) domain
EPKEEPDC_03691 4.93e-95 - - - S - - - CAAX protease self-immunity
EPKEEPDC_03692 2.38e-11 ywlA - - S - - - Uncharacterised protein family (UPF0715)
EPKEEPDC_03693 1.39e-134 - - - S - - - Domain of unknown function (DUF3885)
EPKEEPDC_03696 6.13e-110 - - - E - - - phosphoribosylanthranilate isomerase activity
EPKEEPDC_03697 0.0 xynP - - G ko:K03292 - ko00000 MFS/sugar transport protein
EPKEEPDC_03698 0.0 xynB 3.2.1.37 GH43 G ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
EPKEEPDC_03699 1.23e-275 xylR - - GK - - - ROK family
EPKEEPDC_03700 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
EPKEEPDC_03701 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 xylulose kinase
EPKEEPDC_03702 6.15e-146 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
EPKEEPDC_03703 0.0 - - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
EPKEEPDC_03705 4.16e-279 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EPKEEPDC_03707 5.49e-107 - - - S - - - Protein of unknown function (DUF2691)
EPKEEPDC_03708 3.51e-101 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
EPKEEPDC_03711 1.53e-207 - - - S - - - Thymidylate synthase
EPKEEPDC_03712 8.27e-40 - - - - - - - -
EPKEEPDC_03714 5.34e-166 - - - S - - - Domain of unknown function, YrpD
EPKEEPDC_03717 2.37e-34 tatA - - U ko:K03116,ko:K03117,ko:K03646 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02000,ko02044 protein secretion
EPKEEPDC_03718 1.04e-94 - - - - - - - -
EPKEEPDC_03719 1.81e-103 yndB - - S - - - Activator of Hsp90 ATPase homolog 1-like protein
EPKEEPDC_03722 0.0 yndD1 - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
EPKEEPDC_03723 3.94e-250 yndE7 - - U ko:K06311 - ko00000,ko02000 Spore germination
EPKEEPDC_03724 7.59e-287 - - - S ko:K06293,ko:K06312 - ko00000 Spore germination protein
EPKEEPDC_03725 1.25e-196 yndG - - S - - - DoxX-like family
EPKEEPDC_03726 4.04e-148 - - - S - - - Domain of unknown function (DUF4166)
EPKEEPDC_03727 0.0 yndJ - - S - - - YndJ-like protein
EPKEEPDC_03729 6.31e-173 yndL - - S - - - Replication protein
EPKEEPDC_03730 1.32e-96 yndM - - S - - - Protein of unknown function (DUF2512)
EPKEEPDC_03731 1.74e-101 fosB - - H ko:K11210,ko:K21252 - ko00000,ko01000,ko01504 Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
EPKEEPDC_03732 7.22e-142 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EPKEEPDC_03733 8.5e-65 yneA - - D - - - Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
EPKEEPDC_03734 3.97e-145 yneB - - L - - - resolvase
EPKEEPDC_03735 1.15e-43 ynzC - - S - - - UPF0291 protein
EPKEEPDC_03736 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EPKEEPDC_03737 2.18e-106 yneE - - S - - - Sporulation inhibitor of replication protein sirA
EPKEEPDC_03738 4.36e-39 yneF - - S ko:K09976 - ko00000 UPF0154 protein
EPKEEPDC_03739 4.59e-21 ynzD - - S - - - Spo0E like sporulation regulatory protein
EPKEEPDC_03740 4.13e-165 ccdA - - O ko:K06196 - ko00000,ko02000 cytochrome c biogenesis protein
EPKEEPDC_03741 2.12e-77 ccdB - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 cheY-homologous receiver domain
EPKEEPDC_03742 3.57e-98 yneJ - - O - - - COG4846 Membrane protein involved in cytochrome C biogenesis
EPKEEPDC_03743 3.97e-97 yneK - - S - - - Protein of unknown function (DUF2621)
EPKEEPDC_03744 2.35e-84 cotM - - O ko:K06335 - ko00000 Spore coat protein
EPKEEPDC_03745 5.65e-27 sspP - - S ko:K06433 - ko00000 Belongs to the SspP family
EPKEEPDC_03746 3.27e-21 sspO - - S ko:K06432 - ko00000 Belongs to the SspO family
EPKEEPDC_03747 0.0 citB 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EPKEEPDC_03748 3.07e-119 yneN - - CO - - - alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EPKEEPDC_03749 9.26e-10 - - - S - - - Fur-regulated basic protein B
EPKEEPDC_03751 6.62e-48 tlp - - S ko:K06434 - ko00000 Belongs to the Tlp family
EPKEEPDC_03752 1.4e-95 yneP - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
EPKEEPDC_03753 4.68e-71 yneQ - - - - - - -
EPKEEPDC_03754 8.97e-65 yneR - - S - - - Belongs to the HesB IscA family
EPKEEPDC_03755 3.86e-122 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
EPKEEPDC_03756 1.21e-90 yneT - - S ko:K06929 - ko00000 CoA-binding protein
EPKEEPDC_03757 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
EPKEEPDC_03758 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
EPKEEPDC_03759 1.82e-18 - - - - - - - -
EPKEEPDC_03760 4.16e-73 ynfC - - - - - - -
EPKEEPDC_03761 0.0 alsT - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
EPKEEPDC_03762 0.0 bglC5 3.2.1.4 GH5,GH9 G ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 PFAM glycoside hydrolase family 5
EPKEEPDC_03764 2.36e-315 ynfF 3.2.1.136 GH5 M ko:K15924 - ko00000,ko01000 Belongs to the glycosyl hydrolase 30 family
EPKEEPDC_03765 0.0 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
EPKEEPDC_03766 1.72e-103 yngA - - S - - - membrane
EPKEEPDC_03767 2.74e-210 yngB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
EPKEEPDC_03768 2.01e-134 yngC - - S - - - membrane-associated protein
EPKEEPDC_03769 7.09e-294 yngD - - S ko:K07097 - ko00000 phosphohydrolase (DHH superfamily)
EPKEEPDC_03770 0.0 yngE - - I - - - COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
EPKEEPDC_03771 6.03e-175 yngF - - I - - - Belongs to the enoyl-CoA hydratase isomerase family
EPKEEPDC_03772 6.46e-210 yngG 4.1.3.4 - E ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA lyase
EPKEEPDC_03773 2.4e-41 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin carboxyl carrier protein
EPKEEPDC_03774 5.47e-314 yngH 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
EPKEEPDC_03775 0.0 yngI - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
EPKEEPDC_03776 3.09e-267 yngJ 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
EPKEEPDC_03777 0.0 yngK - - T - - - Glycosyl hydrolase-like 10
EPKEEPDC_03778 6.08e-84 yngL - - S - - - Protein of unknown function (DUF1360)
EPKEEPDC_03779 0.0 - 6.3.2.14 - Q ko:K02364,ko:K15656,ko:K15668 ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024 ko00000,ko00001,ko01000,ko01008 amino acid activation for nonribosomal peptide biosynthetic process
EPKEEPDC_03780 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EPKEEPDC_03781 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EPKEEPDC_03782 0.0 - - - Q ko:K15665 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EPKEEPDC_03783 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EPKEEPDC_03784 0.0 dacC 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
EPKEEPDC_03785 7.83e-240 yoxA 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
EPKEEPDC_03786 9.8e-313 yoeA - - V - - - MATE efflux family protein
EPKEEPDC_03787 7.14e-128 yoeB - - S - - - IseA DL-endopeptidase inhibitor
EPKEEPDC_03789 1.14e-124 - - - L - - - Integrase
EPKEEPDC_03790 3.31e-47 yoeD - - G - - - Helix-turn-helix domain
EPKEEPDC_03791 0.0 ggt 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
EPKEEPDC_03792 8.4e-199 gltR1 - - K ko:K21959 - ko00000,ko03000 Transcriptional regulator
EPKEEPDC_03793 4.88e-236 yogA - - C ko:K13955 - ko00000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
EPKEEPDC_03794 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
EPKEEPDC_03795 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
EPKEEPDC_03796 2.61e-205 gltC - - K ko:K09681 - ko00000,ko03000 Transcriptional regulator
EPKEEPDC_03797 9.09e-260 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EPKEEPDC_03798 2.72e-185 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EPKEEPDC_03799 5.37e-79 rtp - - K - - - Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
EPKEEPDC_03800 4.59e-159 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
EPKEEPDC_03801 3.16e-50 yoxC - - S - - - Bacterial protein of unknown function (DUF948)
EPKEEPDC_03802 4.25e-173 yoxB - - - - - - -
EPKEEPDC_03803 3.84e-121 yoaA 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
EPKEEPDC_03804 6.14e-298 yoaB - - EGP - - - the major facilitator superfamily
EPKEEPDC_03805 0.0 lsrK 2.7.1.189 - G ko:K11216 ko02024,map02024 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
EPKEEPDC_03806 3.36e-234 yoaD 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EPKEEPDC_03807 0.0 yoaE - - C - - - belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EPKEEPDC_03808 2.53e-45 yoaF - - - - - - -
EPKEEPDC_03810 1.46e-19 - - - - - - - -
EPKEEPDC_03811 2.99e-55 - - - S - - - Protein of unknown function (DUF4025)
EPKEEPDC_03812 3.18e-282 yoaH - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 methyl-accepting chemotaxis protein
EPKEEPDC_03813 0.0 yoaI 1.14.14.9 - Q ko:K00483 ko00350,ko01120,ko01220,map00350,map01120,map01220 ko00000,ko00001,ko01000 COG2368 Aromatic ring hydroxylase
EPKEEPDC_03814 1.51e-170 yoaJ - - G ko:K20628 - ko00000 Endoglucanase C-terminal domain subunit and related proteins
EPKEEPDC_03815 2.97e-144 yoaK - - S - - - Membrane
EPKEEPDC_03816 2.78e-250 - 4.2.2.10 - G ko:K01732 - ko00000,ko01000 Amb_all
EPKEEPDC_03817 2.82e-168 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
EPKEEPDC_03820 5.14e-292 oxdD 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
EPKEEPDC_03822 7.59e-07 yoaP - - K - - - YoaP-like
EPKEEPDC_03823 2.09e-110 - - - - - - - -
EPKEEPDC_03824 1.04e-217 yoaR - - V - - - vancomycin resistance protein
EPKEEPDC_03825 3.22e-98 yoaS - - S - - - Protein of unknown function (DUF2975)
EPKEEPDC_03826 7e-40 yozG - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
EPKEEPDC_03827 6.64e-190 yoaT - - S - - - Protein of unknown function (DUF817)
EPKEEPDC_03828 7.78e-202 yoaU - - K - - - LysR substrate binding domain
EPKEEPDC_03829 2.6e-201 yoaV - - EG - - - EamA-like transporter family
EPKEEPDC_03830 3.26e-101 yoaW - - - - - - -
EPKEEPDC_03831 3.43e-147 lin0465 - - S - - - DJ-1/PfpI family
EPKEEPDC_03832 2.54e-215 penP 3.5.2.6 - V ko:K17836,ko:K18766 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 beta-lactamase
EPKEEPDC_03835 0.0 pps 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
EPKEEPDC_03836 7.53e-157 xlnB 3.2.1.8 - G ko:K01181 - ko00000,ko01000 Glycosyl hydrolases family 11
EPKEEPDC_03838 1.08e-61 - - - - - - - -
EPKEEPDC_03839 2.24e-110 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
EPKEEPDC_03840 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
EPKEEPDC_03841 5.65e-132 yokH - - G - - - SMI1 / KNR4 family
EPKEEPDC_03842 0.0 iaaM 1.4.3.4 - E ko:K00274 ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034 ko00000,ko00001,ko00002,ko01000 COG1231 Monoamine oxidase
EPKEEPDC_03843 1.05e-70 csaA - - J ko:K06878 - ko00000 tRNA-binding protein
EPKEEPDC_03844 1.56e-172 yobQ - - K - - - helix_turn_helix, arabinose operon control protein
EPKEEPDC_03845 5.91e-180 - - - J - - - FR47-like protein
EPKEEPDC_03846 4.21e-125 yobS - - K - - - Transcriptional regulator
EPKEEPDC_03847 4.49e-168 yobT - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
EPKEEPDC_03848 2.04e-110 - - - K - - - Bacterial transcription activator, effector binding domain
EPKEEPDC_03849 1.37e-220 yobV - - K - - - WYL domain
EPKEEPDC_03850 2.37e-117 yobW - - - - - - -
EPKEEPDC_03851 2.72e-67 czrA - - K ko:K22043 - ko00000,ko03000 transcriptional
EPKEEPDC_03852 1.79e-145 yocA - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
EPKEEPDC_03853 3.97e-119 yozB - - S ko:K08976 - ko00000 membrane
EPKEEPDC_03854 6.12e-184 - - - - - - - -
EPKEEPDC_03855 1.32e-122 yocC - - - - - - -
EPKEEPDC_03856 1.65e-241 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 peptidase S66
EPKEEPDC_03857 5.67e-258 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
EPKEEPDC_03858 2.37e-250 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EPKEEPDC_03859 4.71e-135 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EPKEEPDC_03861 6.78e-174 yocH - - M - - - COG1388 FOG LysM repeat
EPKEEPDC_03862 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
EPKEEPDC_03863 1.46e-147 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EPKEEPDC_03864 1.42e-107 yocK - - T - - - general stress protein
EPKEEPDC_03865 7.12e-69 yocL - - - - - - -
EPKEEPDC_03866 4.08e-43 - - - - - - - -
EPKEEPDC_03867 6.6e-115 yocM - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
EPKEEPDC_03868 2.94e-55 yozN - - - - - - -
EPKEEPDC_03869 1.83e-49 yocN - - - - - - -
EPKEEPDC_03870 2.17e-74 yozO - - S - - - Bacterial PH domain
EPKEEPDC_03871 1.91e-42 yozC - - - - - - -
EPKEEPDC_03872 0.0 dhaS 1.2.1.3, 1.2.1.39 - C ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
EPKEEPDC_03873 0.0 sqhC 4.2.1.137 - I ko:K18115 - ko00000,ko01000 COG1657 Squalene cyclase
EPKEEPDC_03874 1.12e-210 sodF 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Superoxide dismutase
EPKEEPDC_03875 4.35e-300 yocR - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
EPKEEPDC_03876 1.35e-213 yocS - - S ko:K03453 - ko00000 -transporter
EPKEEPDC_03877 3.02e-263 odhB 2.3.1.61 - C ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
EPKEEPDC_03878 0.0 odhA 1.2.4.2 - C ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
EPKEEPDC_03879 0.0 yojO - - P - - - Von Willebrand factor
EPKEEPDC_03880 2.21e-206 yojN - - S ko:K04748 - ko00000 ATPase family associated with various cellular activities (AAA)
EPKEEPDC_03881 6.01e-141 sodC 1.15.1.1 - P ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EPKEEPDC_03882 1.3e-267 - - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
EPKEEPDC_03883 6.56e-293 yojK - - CG - - - UDP-glucoronosyl and UDP-glucosyl transferase
EPKEEPDC_03884 2.49e-140 dacB 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EPKEEPDC_03886 2.8e-311 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
EPKEEPDC_03887 2.05e-193 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
EPKEEPDC_03888 3.71e-161 yojG - - S ko:K22135 - ko00000,ko01000 deacetylase
EPKEEPDC_03889 2.32e-79 yojF - - S - - - Protein of unknown function (DUF1806)
EPKEEPDC_03890 1.07e-57 - - - - - - - -
EPKEEPDC_03891 1.92e-206 rarD - - S ko:K05786 - ko00000,ko02000 -transporter
EPKEEPDC_03892 2.88e-103 yozR - - S - - - COG0071 Molecular chaperone (small heat shock protein)
EPKEEPDC_03893 5.59e-14 - - - - - - - -
EPKEEPDC_03894 1.78e-287 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
EPKEEPDC_03895 3.97e-84 iolK - - S - - - tautomerase
EPKEEPDC_03896 2.63e-73 yodB - - K - - - transcriptional
EPKEEPDC_03897 1.11e-139 yodC - - C - - - nitroreductase
EPKEEPDC_03898 1.31e-146 yahD - - S ko:K06999 - ko00000 Carboxylesterase
EPKEEPDC_03899 4.8e-223 yodE - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
EPKEEPDC_03900 2.36e-38 - - - S - - - Protein of unknown function (DUF3311)
EPKEEPDC_03901 0.0 yodF - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EPKEEPDC_03902 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
EPKEEPDC_03903 2.05e-164 yodH - - Q - - - Methyltransferase
EPKEEPDC_03904 4.86e-41 yodI - - - - - - -
EPKEEPDC_03905 2.69e-189 yodJ 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
EPKEEPDC_03906 1.68e-163 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
EPKEEPDC_03907 2.08e-12 - - - - - - - -
EPKEEPDC_03908 1.17e-71 yodL - - S - - - YodL-like
EPKEEPDC_03909 7.78e-136 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
EPKEEPDC_03910 5.18e-34 yozD - - S - - - YozD-like protein
EPKEEPDC_03912 7.44e-159 yodN - - - - - - -
EPKEEPDC_03913 7.3e-50 yozE - - S - - - Belongs to the UPF0346 family
EPKEEPDC_03914 4.03e-62 yokU - - S - - - YokU-like protein, putative antitoxin
EPKEEPDC_03915 1.91e-64 kamA 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 lysine 2,3-aminomutase
EPKEEPDC_03916 4.68e-100 - - - M - - - Belongs to the peptidase S8 family
EPKEEPDC_03917 2.52e-216 lanT - - P ko:K06148,ko:K13409,ko:K20344,ko:K20386 ko02010,ko02024,ko04626,map02010,map02024,map04626 ko00000,ko00001,ko00002,ko02000,ko02044 Toxin secretion ABC transporter, ATP-binding permease protein
EPKEEPDC_03919 7.76e-61 - - - S - - - Flavodoxin-like fold
EPKEEPDC_03920 2.46e-230 salB - - V ko:K20385 ko02024,map02024 ko00000,ko00001 Domain of unknown function (DUF4135)
EPKEEPDC_03921 1.7e-16 - - - S - - - Two-component Enterococcus faecalis cytolysin (EFC)
EPKEEPDC_03924 1.4e-62 yokU - - S - - - YokU-like protein, putative antitoxin
EPKEEPDC_03925 0.0 kamA 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 lysine 2,3-aminomutase
EPKEEPDC_03926 1.24e-195 yodP 2.3.1.264 - K ko:K21935 - ko00000,ko01000 Acetyltransferase (GNAT) family
EPKEEPDC_03927 0.0 yodQ 3.5.1.16, 3.5.1.18 - E ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetylornithine deacetylase
EPKEEPDC_03928 9.44e-153 atoA 2.8.3.8, 2.8.3.9 - I ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
EPKEEPDC_03929 5.65e-160 atoD 2.8.3.8, 2.8.3.9 - I ko:K01034 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EPKEEPDC_03930 5.62e-316 yodT - - H - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EPKEEPDC_03933 1.33e-182 yiiD - - K ko:K06323 - ko00000 acetyltransferase
EPKEEPDC_03934 0.0 cgeD - - M ko:K06322 - ko00000 maturation of the outermost layer of the spore
EPKEEPDC_03935 1.06e-59 cgeC - - - ko:K06321 - ko00000 -
EPKEEPDC_03936 3.1e-83 cgeA - - - ko:K06319 - ko00000 -
EPKEEPDC_03937 9.37e-228 cgeB - - S ko:K06320 - ko00000 Spore maturation protein
EPKEEPDC_03938 1.9e-278 phy 3.1.3.8 - I ko:K01083 ko00562,map00562 ko00000,ko00001,ko01000 Myo-inositol-hexaphosphate 3-phosphohydrolase
EPKEEPDC_03939 2.36e-157 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
EPKEEPDC_03940 4.13e-102 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
EPKEEPDC_03941 9.83e-133 msrB 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EPKEEPDC_03942 4.14e-94 ypoP - - K - - - transcriptional
EPKEEPDC_03943 7.03e-290 mepA - - V - - - MATE efflux family protein
EPKEEPDC_03944 2.13e-40 ypmT - - S - - - Uncharacterized ympT
EPKEEPDC_03945 1.95e-128 ypmS - - S - - - protein conserved in bacteria
EPKEEPDC_03946 2.58e-178 ypmR - - E - - - GDSL-like Lipase/Acylhydrolase
EPKEEPDC_03947 2.77e-140 ypmQ - - S ko:K07152 - ko00000,ko03029 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
EPKEEPDC_03948 1.28e-54 ypmP - - S - - - Protein of unknown function (DUF2535)
EPKEEPDC_03949 1.04e-309 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EPKEEPDC_03950 3.85e-234 yplP - - K - - - Transcriptional regulator
EPKEEPDC_03951 8.03e-143 yplQ - - S ko:K11068 - ko00000,ko02042 protein, Hemolysin III
EPKEEPDC_03952 8.12e-144 ypkP 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
EPKEEPDC_03953 9.58e-122 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EPKEEPDC_03954 8.91e-121 ltrC 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
EPKEEPDC_03955 3.47e-148 ypjP - - S - - - YpjP-like protein
EPKEEPDC_03956 6.15e-187 ypiP - - AJ - - - Putative SAM-dependent methyltransferase
EPKEEPDC_03957 7.97e-98 yphP - - S - - - Belongs to the UPF0403 family
EPKEEPDC_03958 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
EPKEEPDC_03959 3.14e-201 ypgR - - C - - - COG0694 Thioredoxin-like proteins and domains
EPKEEPDC_03960 4.18e-141 yagB - - S ko:K06950 - ko00000 phosphohydrolase
EPKEEPDC_03961 3.13e-114 bsaA 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
EPKEEPDC_03962 6.09e-225 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EPKEEPDC_03963 1.28e-276 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
EPKEEPDC_03964 5.12e-42 cspD - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
EPKEEPDC_03965 1.17e-22 degR - - - - - - -
EPKEEPDC_03966 1.05e-40 - - - S - - - Protein of unknown function (DUF2564)
EPKEEPDC_03967 1.54e-37 ypeQ - - S - - - Zinc-finger
EPKEEPDC_03968 2.31e-162 ypeP 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 COG0328 Ribonuclease HI
EPKEEPDC_03969 3.27e-136 ypdP - - S ko:K09125 - ko00000 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EPKEEPDC_03970 6.28e-87 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease
EPKEEPDC_03971 5.23e-05 - - - - ko:K06429 - ko00000 -
EPKEEPDC_03972 2.26e-213 ypcP - - L - - - 5'3' exonuclease
EPKEEPDC_03973 1.08e-11 - - - - - - - -
EPKEEPDC_03974 1.17e-51 ypbS - - S - - - Protein of unknown function (DUF2533)
EPKEEPDC_03975 0.0 ypbR - - S - - - Dynamin family
EPKEEPDC_03976 3.33e-113 ypbQ - - S ko:K16168 - ko00000,ko01008 protein conserved in bacteria
EPKEEPDC_03977 1.52e-264 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
EPKEEPDC_03978 1e-290 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
EPKEEPDC_03979 5.51e-127 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
EPKEEPDC_03980 0.0 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EPKEEPDC_03981 4.09e-224 kdgT - - P ko:K02526 - ko00000,ko02000 The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
EPKEEPDC_03982 1.2e-131 kdgA 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 2-dehydro-3-deoxy-phosphogluconate aldolase
EPKEEPDC_03983 1.15e-236 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0524 Sugar kinases, ribokinase family
EPKEEPDC_03984 7.8e-238 kdgR - - K ko:K02525 - ko00000,ko03000 transcriptional
EPKEEPDC_03985 2.96e-203 kduI 5.3.1.17 - G ko:K01815 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
EPKEEPDC_03986 1.09e-174 kduD 1.1.1.127 - IQ ko:K00065 ko00040,map00040 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EPKEEPDC_03987 0.0 ypvA 3.6.4.12 - KL ko:K03722 - ko00000,ko01000,ko03400 COG1199 Rad3-related DNA helicases
EPKEEPDC_03989 4.71e-285 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
EPKEEPDC_03990 2.97e-60 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
EPKEEPDC_03991 4.85e-128 ypsA - - S - - - Belongs to the UPF0398 family
EPKEEPDC_03992 5.92e-300 yprB - - L ko:K07502 - ko00000 RNase_H superfamily
EPKEEPDC_03993 0.0 yprA - - L ko:K06877 - ko00000 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
EPKEEPDC_03994 7.43e-110 ypqE - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 COG2190 Phosphotransferase system IIA components
EPKEEPDC_03995 2.93e-93 hspX - - O ko:K06335,ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
EPKEEPDC_03996 8.72e-68 yppG - - S - - - YppG-like protein
EPKEEPDC_03997 9.21e-11 - - - S - - - YppF-like protein
EPKEEPDC_03998 1.42e-10 yppE - - S - - - Bacterial domain of unknown function (DUF1798)
EPKEEPDC_04001 1.7e-236 yppC - - S - - - Protein of unknown function (DUF2515)
EPKEEPDC_04002 3.2e-150 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
EPKEEPDC_04003 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
EPKEEPDC_04004 4.78e-120 ypoC - - - - - - -
EPKEEPDC_04005 3.57e-158 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EPKEEPDC_04006 6.62e-165 dnaD - - L ko:K02086 - ko00000 DNA replication protein DnaD
EPKEEPDC_04007 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 asparaginyl-tRNA
EPKEEPDC_04008 2.53e-284 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
EPKEEPDC_04009 7.61e-102 ypmB - - S - - - protein conserved in bacteria
EPKEEPDC_04010 1.52e-32 ypmA - - S - - - Protein of unknown function (DUF4264)
EPKEEPDC_04011 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
EPKEEPDC_04012 4.16e-85 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EPKEEPDC_04013 3.03e-197 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EPKEEPDC_04014 4.85e-194 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
EPKEEPDC_04015 5.68e-233 birA 6.3.4.15 - K ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
EPKEEPDC_04016 1.83e-279 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
EPKEEPDC_04017 8.18e-266 bshA - GT4 M ko:K00754 - ko00000,ko01000 N-acetyl-alpha-D-glucosaminyl L-malate synthase
EPKEEPDC_04018 1.89e-166 bshB1 - - S ko:K01463 - ko00000,ko01000 proteins, LmbE homologs
EPKEEPDC_04019 1.03e-92 mgsA 4.2.3.3 - G ko:K01734 ko00640,ko01120,map00640,map01120 ko00000,ko00001,ko01000 methylglyoxal synthase
EPKEEPDC_04020 2.4e-189 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
EPKEEPDC_04021 1.01e-73 ypjD - - S - - - Nucleotide pyrophosphohydrolase
EPKEEPDC_04022 3.7e-200 ypjC - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
EPKEEPDC_04023 2.79e-182 ypjB - - S - - - sporulation protein
EPKEEPDC_04024 6.63e-125 ypjA - - S - - - membrane
EPKEEPDC_04025 5.71e-191 qcrC - - C ko:K03888 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Menaquinol-cytochrome c reductase cytochrome b c subunit
EPKEEPDC_04026 8.76e-166 qcrB - - C ko:K03887 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG1290 Cytochrome b subunit of the bc complex
EPKEEPDC_04027 3.35e-126 qcrA - - C ko:K03886 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Menaquinol-cytochrome c reductase
EPKEEPDC_04028 5.55e-100 ypiF - - S - - - Protein of unknown function (DUF2487)
EPKEEPDC_04029 1.29e-129 ypiB - - S - - - Belongs to the UPF0302 family
EPKEEPDC_04030 8.74e-298 ypiA - - S - - - COG0457 FOG TPR repeat
EPKEEPDC_04031 4.03e-301 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
EPKEEPDC_04032 1.21e-264 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
EPKEEPDC_04033 1.24e-256 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EPKEEPDC_04034 2.21e-185 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
EPKEEPDC_04035 4.44e-293 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
EPKEEPDC_04036 3.85e-151 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
EPKEEPDC_04037 4.18e-145 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
EPKEEPDC_04038 5e-229 trpD 2.4.2.18, 4.1.3.27 - E ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EPKEEPDC_04039 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EPKEEPDC_04040 9.82e-84 aroH 5.4.99.5 - E ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
EPKEEPDC_04041 3.31e-262 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EPKEEPDC_04042 1.44e-277 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EPKEEPDC_04043 3.03e-182 cheR 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 COG1352 Methylase of chemotaxis methyl-accepting proteins
EPKEEPDC_04044 2.17e-104 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
EPKEEPDC_04045 4.09e-249 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
EPKEEPDC_04046 1.34e-169 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
EPKEEPDC_04047 8.72e-178 hepS 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
EPKEEPDC_04048 5.13e-46 mtrB - - K ko:K06285 - ko00000,ko03000 Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
EPKEEPDC_04049 4.41e-131 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
EPKEEPDC_04050 1.07e-57 hbs - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
EPKEEPDC_04051 0.0 spoIVA - - S ko:K06398 - ko00000 ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EPKEEPDC_04052 1.02e-174 yphF - - - - - - -
EPKEEPDC_04053 7.09e-27 yphE - - S - - - Protein of unknown function (DUF2768)
EPKEEPDC_04054 1.05e-229 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
EPKEEPDC_04055 1.72e-315 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
EPKEEPDC_04056 2.06e-38 ypzH - - - - - - -
EPKEEPDC_04057 4.35e-207 yphB - - S ko:K05739 - ko00000 YIEGIA protein
EPKEEPDC_04058 4.34e-131 yphA - - - - - - -
EPKEEPDC_04059 1.13e-11 - - - S - - - YpzI-like protein
EPKEEPDC_04060 2.58e-232 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
EPKEEPDC_04061 7.8e-262 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
EPKEEPDC_04062 3.91e-144 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
EPKEEPDC_04063 1.39e-29 - - - S - - - Family of unknown function (DUF5359)
EPKEEPDC_04064 1.27e-141 ypfA - - M - - - Flagellar protein YcgR
EPKEEPDC_04065 0.0 ypeB - - H ko:K06313 - ko00000 sporulation protein
EPKEEPDC_04066 6.93e-208 sleB 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Spore cortex-lytic enzyme
EPKEEPDC_04067 4.33e-154 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
EPKEEPDC_04068 4.96e-222 ypdA 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 COG0492 Thioredoxin reductase
EPKEEPDC_04069 1.42e-308 gudB 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
EPKEEPDC_04070 5.56e-136 mecB - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
EPKEEPDC_04071 1.02e-186 ypbG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
EPKEEPDC_04072 8.23e-106 ypbF - - S - - - Protein of unknown function (DUF2663)
EPKEEPDC_04073 8.61e-143 ypbE - - M - - - Lysin motif
EPKEEPDC_04074 3.55e-128 ypbD - - S ko:K07052 - ko00000 metal-dependent membrane protease
EPKEEPDC_04075 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
EPKEEPDC_04076 2.12e-253 ypbB 5.1.3.1 - S ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 protein conserved in bacteria
EPKEEPDC_04077 8.35e-55 fer - - C ko:K05337 - ko00000 Ferredoxin
EPKEEPDC_04078 3.07e-122 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EPKEEPDC_04079 0.0 serA 1.1.1.399, 1.1.1.95 - E ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EPKEEPDC_04080 1.87e-171 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
EPKEEPDC_04081 7.95e-236 rsiX - - - - - - -
EPKEEPDC_04082 1.08e-133 sigX - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
EPKEEPDC_04083 0.0 resE 2.7.13.3 - T ko:K07651 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EPKEEPDC_04084 1.69e-171 resD - - T ko:K07775 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EPKEEPDC_04085 4.67e-279 resC - - O - - - 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
EPKEEPDC_04086 0.0 resB - - O ko:K07399 - ko00000 COG1333 ResB protein required for cytochrome c biosynthesis
EPKEEPDC_04087 1.5e-128 resA - - CO - - - Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
EPKEEPDC_04088 3.66e-168 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
EPKEEPDC_04089 8.62e-114 spmB - - S ko:K06374 - ko00000 Spore maturation protein
EPKEEPDC_04090 7.57e-135 spmA - - S ko:K06373 - ko00000 Spore maturation protein
EPKEEPDC_04091 9.67e-272 dacB 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
EPKEEPDC_04092 1.69e-125 ypuI - - S - - - Protein of unknown function (DUF3907)
EPKEEPDC_04093 2e-135 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EPKEEPDC_04094 1.33e-167 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EPKEEPDC_04095 2.06e-119 ypuF - - S ko:K09763 - ko00000 Domain of unknown function (DUF309)
EPKEEPDC_04096 1.12e-83 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EPKEEPDC_04097 8.41e-107 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
EPKEEPDC_04098 3.12e-292 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EPKEEPDC_04099 3.55e-147 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
EPKEEPDC_04100 2.07e-260 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EPKEEPDC_04101 5.98e-72 ypuD - - - - - - -
EPKEEPDC_04102 1.18e-132 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
EPKEEPDC_04103 1.02e-42 ypzJ - - S ko:K07069 - ko00000 nucleic-acid-binding protein containing a Zn-ribbon domain
EPKEEPDC_04105 1.23e-105 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EPKEEPDC_04106 8.93e-192 ypuA - - S - - - Secreted protein
EPKEEPDC_04107 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
EPKEEPDC_04108 0.0 spoVAF - - EG ko:K06408 - ko00000 Stage V sporulation protein AF
EPKEEPDC_04109 1.85e-143 - - - S ko:K06407 - ko00000 stage V sporulation protein
EPKEEPDC_04110 2.15e-75 spoVAEB - - S ko:K06407 - ko00000 stage V sporulation protein
EPKEEPDC_04111 6.02e-246 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
EPKEEPDC_04112 6.71e-102 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
EPKEEPDC_04113 5.43e-90 spoVAB - - S ko:K06404 - ko00000 Stage V sporulation protein AB
EPKEEPDC_04114 1.15e-143 spoVAA - - S ko:K06403 - ko00000 Stage V sporulation protein AA
EPKEEPDC_04115 1.18e-174 sigF - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EPKEEPDC_04116 6.78e-100 spoIIAB 2.7.11.1 - F ko:K06379 - ko00000,ko01000 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
EPKEEPDC_04117 3e-76 spoIIAA - - T ko:K06378 - ko00000 Belongs to the anti-sigma-factor antagonist family
EPKEEPDC_04118 5.58e-270 dacF 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
EPKEEPDC_04119 1.39e-190 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EPKEEPDC_04120 2.77e-293 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
EPKEEPDC_04121 3.91e-214 xerD - - L ko:K04763 - ko00000,ko03036 recombinase XerD
EPKEEPDC_04122 2.73e-50 - - - S - - - Protein of unknown function (DUF4227)
EPKEEPDC_04123 2.26e-104 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
EPKEEPDC_04124 1.96e-139 spoIIM - - S ko:K06384 - ko00000 Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
EPKEEPDC_04125 5.16e-34 yqkK - - - - - - -
EPKEEPDC_04126 5.62e-309 mleA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
EPKEEPDC_04127 1.14e-309 mleN - - C ko:K03315 - ko00000,ko02000 Na H antiporter
EPKEEPDC_04128 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Aspartate ammonia-lyase
EPKEEPDC_04129 1.03e-237 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase
EPKEEPDC_04130 3.18e-77 ansR - - K - - - Transcriptional regulator
EPKEEPDC_04131 3.56e-281 yqxK - - L - - - DNA helicase
EPKEEPDC_04132 4.07e-120 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
EPKEEPDC_04133 5.78e-10 - - - S - - - Protein of unknown function (DUF3936)
EPKEEPDC_04134 3.61e-215 yqkF - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
EPKEEPDC_04135 2.28e-25 yqkE - - S - - - Protein of unknown function (DUF3886)
EPKEEPDC_04136 1.61e-222 yqkD - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
EPKEEPDC_04137 1.12e-53 yqkC - - S - - - Protein of unknown function (DUF2552)
EPKEEPDC_04138 6.17e-73 yqkB - - S - - - Belongs to the HesB IscA family
EPKEEPDC_04139 9.27e-248 yqkA - - K - - - GrpB protein
EPKEEPDC_04140 2.25e-78 yqjZ - - S - - - enzyme involved in biosynthesis of extracellular polysaccharides
EPKEEPDC_04141 5.46e-113 yqjY - - K ko:K06977 - ko00000 acetyltransferase
EPKEEPDC_04142 9.27e-66 yqiX - - S - - - YolD-like protein
EPKEEPDC_04143 2.72e-302 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EPKEEPDC_04145 2.01e-285 yqjV - - G - - - Major Facilitator Superfamily
EPKEEPDC_04147 9.03e-94 yqjT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EPKEEPDC_04148 6.6e-229 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
EPKEEPDC_04149 0.0 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
EPKEEPDC_04150 3.98e-184 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
EPKEEPDC_04151 1.33e-228 yqjP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
EPKEEPDC_04152 9.32e-188 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EPKEEPDC_04153 0.0 rocB - - E - - - arginine degradation protein
EPKEEPDC_04154 1.72e-245 namA 1.6.99.1 - C ko:K00354 - ko00000,ko01000 Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
EPKEEPDC_04155 3.17e-187 yqjL - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
EPKEEPDC_04156 8.59e-27 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
EPKEEPDC_04157 2.2e-221 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
EPKEEPDC_04158 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EPKEEPDC_04159 0.0 gnd 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EPKEEPDC_04160 6.41e-300 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EPKEEPDC_04161 1.77e-32 yqzJ - - - - - - -
EPKEEPDC_04162 4.2e-178 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EPKEEPDC_04163 7.46e-176 yqjF - - S ko:K09166 - ko00000 Uncharacterized conserved protein (COG2071)
EPKEEPDC_04164 5.26e-259 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 COG2195 Di- and tripeptidases
EPKEEPDC_04165 0.0 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
EPKEEPDC_04166 1.9e-94 mce 5.1.99.1 - E ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0346 Lactoylglutathione lyase and related lyases
EPKEEPDC_04168 2.32e-126 yqjB - - S - - - protein conserved in bacteria
EPKEEPDC_04169 4.95e-221 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
EPKEEPDC_04170 5.2e-166 artM 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
EPKEEPDC_04171 8.94e-143 artQ - - E ko:K02029 - ko00000,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
EPKEEPDC_04172 1.43e-175 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
EPKEEPDC_04173 3.79e-101 yqiW - - S - - - Belongs to the UPF0403 family
EPKEEPDC_04174 9.96e-213 bmrU - - I - - - COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
EPKEEPDC_04175 3.6e-266 norA - - EGP ko:K08153,ko:K19576,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
EPKEEPDC_04176 6.38e-195 - - - K ko:K19575 - ko00000,ko00002,ko03000 helix_turn_helix, mercury resistance
EPKEEPDC_04177 3.77e-288 bkdB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
EPKEEPDC_04178 6.92e-235 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
EPKEEPDC_04179 1.11e-237 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
EPKEEPDC_04180 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
EPKEEPDC_04181 1.18e-255 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Belongs to the acetokinase family
EPKEEPDC_04182 1.92e-262 ldh 1.4.1.9 - E ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
EPKEEPDC_04183 6.35e-201 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 phosphate butyryltransferase
EPKEEPDC_04184 0.0 bkdR - - KT - - - Transcriptional regulator
EPKEEPDC_04185 1.56e-46 yqzF - - S - - - Protein of unknown function (DUF2627)
EPKEEPDC_04186 1.52e-209 prpB 4.1.3.30, 5.4.2.9 - G ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EPKEEPDC_04187 0.0 prpD 4.2.1.79 - S ko:K01720 ko00640,map00640 ko00000,ko00001,ko01000 2-methylcitrate dehydratase
EPKEEPDC_04188 2.94e-261 mmgD 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
EPKEEPDC_04189 4.95e-268 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
EPKEEPDC_04190 2.31e-197 mmgB 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
EPKEEPDC_04191 1.1e-278 mmgA 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
EPKEEPDC_04192 3.39e-168 yqiK 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
EPKEEPDC_04193 1.63e-138 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Cell wall hydrolase autolysin
EPKEEPDC_04194 4.74e-37 - - - - - - - -
EPKEEPDC_04195 5.68e-273 yqiG - - C - - - COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
EPKEEPDC_04197 5.43e-186 spo0A - - KT ko:K07699 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
EPKEEPDC_04198 2.96e-302 spoIVB 3.4.21.116 - M ko:K06399 - ko00000,ko01000,ko01002 Stage IV sporulation protein B
EPKEEPDC_04199 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
EPKEEPDC_04200 8.85e-102 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
EPKEEPDC_04201 2.93e-197 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 rRNA methylase
EPKEEPDC_04202 8.5e-217 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)