ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
NIIKMLNH_00001 0.0 yoaI 1.14.14.9 - Q ko:K00483 ko00350,ko01120,ko01220,map00350,map01120,map01220 ko00000,ko00001,ko01000 COG2368 Aromatic ring hydroxylase
NIIKMLNH_00002 1.51e-170 yoaJ - - G ko:K20628 - ko00000 Endoglucanase C-terminal domain subunit and related proteins
NIIKMLNH_00003 2.97e-144 yoaK - - S - - - Membrane
NIIKMLNH_00004 2.78e-250 - 4.2.2.10 - G ko:K01732 - ko00000,ko01000 Amb_all
NIIKMLNH_00005 2.82e-168 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
NIIKMLNH_00008 5.14e-292 oxdD 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
NIIKMLNH_00010 7.59e-07 yoaP - - K - - - YoaP-like
NIIKMLNH_00011 2.09e-110 - - - - - - - -
NIIKMLNH_00012 1.04e-217 yoaR - - V - - - vancomycin resistance protein
NIIKMLNH_00013 3.22e-98 yoaS - - S - - - Protein of unknown function (DUF2975)
NIIKMLNH_00014 7e-40 yozG - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
NIIKMLNH_00015 6.64e-190 yoaT - - S - - - Protein of unknown function (DUF817)
NIIKMLNH_00016 7.78e-202 yoaU - - K - - - LysR substrate binding domain
NIIKMLNH_00017 2.6e-201 yoaV - - EG - - - EamA-like transporter family
NIIKMLNH_00018 3.26e-101 yoaW - - - - - - -
NIIKMLNH_00019 3.43e-147 lin0465 - - S - - - DJ-1/PfpI family
NIIKMLNH_00020 2.54e-215 penP 3.5.2.6 - V ko:K17836,ko:K18766 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 beta-lactamase
NIIKMLNH_00023 0.0 pps 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
NIIKMLNH_00024 7.53e-157 xlnB 3.2.1.8 - G ko:K01181 - ko00000,ko01000 Glycosyl hydrolases family 11
NIIKMLNH_00026 1.08e-61 - - - - - - - -
NIIKMLNH_00027 2.24e-110 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
NIIKMLNH_00028 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
NIIKMLNH_00029 5.65e-132 yokH - - G - - - SMI1 / KNR4 family
NIIKMLNH_00030 0.0 iaaM 1.4.3.4 - E ko:K00274 ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034 ko00000,ko00001,ko00002,ko01000 COG1231 Monoamine oxidase
NIIKMLNH_00031 1.05e-70 csaA - - J ko:K06878 - ko00000 tRNA-binding protein
NIIKMLNH_00032 1.56e-172 yobQ - - K - - - helix_turn_helix, arabinose operon control protein
NIIKMLNH_00033 5.91e-180 - - - J - - - FR47-like protein
NIIKMLNH_00034 4.21e-125 yobS - - K - - - Transcriptional regulator
NIIKMLNH_00035 4.49e-168 yobT - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
NIIKMLNH_00036 2.04e-110 - - - K - - - Bacterial transcription activator, effector binding domain
NIIKMLNH_00037 1.37e-220 yobV - - K - - - WYL domain
NIIKMLNH_00038 2.37e-117 yobW - - - - - - -
NIIKMLNH_00039 2.72e-67 czrA - - K ko:K22043 - ko00000,ko03000 transcriptional
NIIKMLNH_00040 1.79e-145 yocA - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
NIIKMLNH_00041 3.97e-119 yozB - - S ko:K08976 - ko00000 membrane
NIIKMLNH_00042 6.12e-184 - - - - - - - -
NIIKMLNH_00043 1.32e-122 yocC - - - - - - -
NIIKMLNH_00044 1.65e-241 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 peptidase S66
NIIKMLNH_00045 5.67e-258 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
NIIKMLNH_00046 2.37e-250 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NIIKMLNH_00047 4.71e-135 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NIIKMLNH_00048 6.78e-174 yocH - - M - - - COG1388 FOG LysM repeat
NIIKMLNH_00049 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
NIIKMLNH_00050 1.46e-147 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NIIKMLNH_00051 1.42e-107 yocK - - T - - - general stress protein
NIIKMLNH_00052 7.12e-69 yocL - - - - - - -
NIIKMLNH_00053 4.08e-43 - - - - - - - -
NIIKMLNH_00054 6.6e-115 yocM - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
NIIKMLNH_00055 2.94e-55 yozN - - - - - - -
NIIKMLNH_00056 1.83e-49 yocN - - - - - - -
NIIKMLNH_00057 2.17e-74 yozO - - S - - - Bacterial PH domain
NIIKMLNH_00058 1.91e-42 yozC - - - - - - -
NIIKMLNH_00059 0.0 dhaS 1.2.1.3, 1.2.1.39 - C ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
NIIKMLNH_00060 0.0 sqhC 4.2.1.137 - I ko:K18115 - ko00000,ko01000 COG1657 Squalene cyclase
NIIKMLNH_00061 1.12e-210 sodF 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Superoxide dismutase
NIIKMLNH_00062 4.35e-300 yocR - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
NIIKMLNH_00063 1.35e-213 yocS - - S ko:K03453 - ko00000 -transporter
NIIKMLNH_00064 3.02e-263 odhB 2.3.1.61 - C ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
NIIKMLNH_00065 0.0 odhA 1.2.4.2 - C ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
NIIKMLNH_00066 0.0 yojO - - P - - - Von Willebrand factor
NIIKMLNH_00067 2.21e-206 yojN - - S ko:K04748 - ko00000 ATPase family associated with various cellular activities (AAA)
NIIKMLNH_00068 6.01e-141 sodC 1.15.1.1 - P ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NIIKMLNH_00069 1.3e-267 - - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
NIIKMLNH_00070 6.56e-293 yojK - - CG - - - UDP-glucoronosyl and UDP-glucosyl transferase
NIIKMLNH_00071 2.49e-140 dacB 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NIIKMLNH_00073 2.8e-311 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
NIIKMLNH_00074 2.05e-193 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NIIKMLNH_00075 3.71e-161 yojG - - S ko:K22135 - ko00000,ko01000 deacetylase
NIIKMLNH_00076 2.32e-79 yojF - - S - - - Protein of unknown function (DUF1806)
NIIKMLNH_00077 1.07e-57 - - - - - - - -
NIIKMLNH_00078 1.92e-206 rarD - - S ko:K05786 - ko00000,ko02000 -transporter
NIIKMLNH_00079 2.88e-103 yozR - - S - - - COG0071 Molecular chaperone (small heat shock protein)
NIIKMLNH_00080 1.78e-287 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
NIIKMLNH_00081 3.97e-84 iolK - - S - - - tautomerase
NIIKMLNH_00082 2.63e-73 yodB - - K - - - transcriptional
NIIKMLNH_00083 1.11e-139 yodC - - C - - - nitroreductase
NIIKMLNH_00084 1.31e-146 yahD - - S ko:K06999 - ko00000 Carboxylesterase
NIIKMLNH_00085 4.8e-223 yodE - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
NIIKMLNH_00086 2.36e-38 - - - S - - - Protein of unknown function (DUF3311)
NIIKMLNH_00087 0.0 yodF - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NIIKMLNH_00088 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
NIIKMLNH_00089 2.05e-164 yodH - - Q - - - Methyltransferase
NIIKMLNH_00090 4.86e-41 yodI - - - - - - -
NIIKMLNH_00091 2.69e-189 yodJ 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
NIIKMLNH_00092 1.68e-163 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
NIIKMLNH_00093 2.08e-12 - - - - - - - -
NIIKMLNH_00094 1.17e-71 yodL - - S - - - YodL-like
NIIKMLNH_00095 7.78e-136 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
NIIKMLNH_00096 5.18e-34 yozD - - S - - - YozD-like protein
NIIKMLNH_00098 7.44e-159 yodN - - - - - - -
NIIKMLNH_00099 7.3e-50 yozE - - S - - - Belongs to the UPF0346 family
NIIKMLNH_00100 4.03e-62 yokU - - S - - - YokU-like protein, putative antitoxin
NIIKMLNH_00101 1.91e-64 kamA 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 lysine 2,3-aminomutase
NIIKMLNH_00102 4.68e-100 - - - M - - - Belongs to the peptidase S8 family
NIIKMLNH_00103 2.52e-216 lanT - - P ko:K06148,ko:K13409,ko:K20344,ko:K20386 ko02010,ko02024,ko04626,map02010,map02024,map04626 ko00000,ko00001,ko00002,ko02000,ko02044 Toxin secretion ABC transporter, ATP-binding permease protein
NIIKMLNH_00105 7.76e-61 - - - S - - - Flavodoxin-like fold
NIIKMLNH_00106 2.46e-230 salB - - V ko:K20385 ko02024,map02024 ko00000,ko00001 Domain of unknown function (DUF4135)
NIIKMLNH_00107 1.7e-16 - - - S - - - Two-component Enterococcus faecalis cytolysin (EFC)
NIIKMLNH_00110 1.4e-62 yokU - - S - - - YokU-like protein, putative antitoxin
NIIKMLNH_00111 0.0 kamA 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 lysine 2,3-aminomutase
NIIKMLNH_00112 1.24e-195 yodP 2.3.1.264 - K ko:K21935 - ko00000,ko01000 Acetyltransferase (GNAT) family
NIIKMLNH_00113 0.0 yodQ 3.5.1.16, 3.5.1.18 - E ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetylornithine deacetylase
NIIKMLNH_00114 9.44e-153 atoA 2.8.3.8, 2.8.3.9 - I ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
NIIKMLNH_00115 5.65e-160 atoD 2.8.3.8, 2.8.3.9 - I ko:K01034 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NIIKMLNH_00116 5.62e-316 yodT - - H - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NIIKMLNH_00118 1.33e-182 yiiD - - K ko:K06323 - ko00000 acetyltransferase
NIIKMLNH_00119 0.0 cgeD - - M ko:K06322 - ko00000 maturation of the outermost layer of the spore
NIIKMLNH_00120 1.06e-59 cgeC - - - ko:K06321 - ko00000 -
NIIKMLNH_00121 3.1e-83 cgeA - - - ko:K06319 - ko00000 -
NIIKMLNH_00122 9.37e-228 cgeB - - S ko:K06320 - ko00000 Spore maturation protein
NIIKMLNH_00123 1.9e-278 phy 3.1.3.8 - I ko:K01083 ko00562,map00562 ko00000,ko00001,ko01000 Myo-inositol-hexaphosphate 3-phosphohydrolase
NIIKMLNH_00124 2.36e-157 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
NIIKMLNH_00125 4.13e-102 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
NIIKMLNH_00126 9.83e-133 msrB 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NIIKMLNH_00127 4.14e-94 ypoP - - K - - - transcriptional
NIIKMLNH_00128 7.03e-290 mepA - - V - - - MATE efflux family protein
NIIKMLNH_00129 2.13e-40 ypmT - - S - - - Uncharacterized ympT
NIIKMLNH_00130 1.95e-128 ypmS - - S - - - protein conserved in bacteria
NIIKMLNH_00131 2.58e-178 ypmR - - E - - - GDSL-like Lipase/Acylhydrolase
NIIKMLNH_00132 2.77e-140 ypmQ - - S ko:K07152 - ko00000,ko03029 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
NIIKMLNH_00133 1.28e-54 ypmP - - S - - - Protein of unknown function (DUF2535)
NIIKMLNH_00134 1.04e-309 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NIIKMLNH_00135 3.85e-234 yplP - - K - - - Transcriptional regulator
NIIKMLNH_00136 8.03e-143 yplQ - - S ko:K11068 - ko00000,ko02042 protein, Hemolysin III
NIIKMLNH_00137 8.12e-144 ypkP 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
NIIKMLNH_00138 9.58e-122 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NIIKMLNH_00139 8.91e-121 ltrC 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
NIIKMLNH_00140 3.47e-148 ypjP - - S - - - YpjP-like protein
NIIKMLNH_00141 6.15e-187 ypiP - - AJ - - - Putative SAM-dependent methyltransferase
NIIKMLNH_00142 7.97e-98 yphP - - S - - - Belongs to the UPF0403 family
NIIKMLNH_00143 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
NIIKMLNH_00144 3.14e-201 ypgR - - C - - - COG0694 Thioredoxin-like proteins and domains
NIIKMLNH_00145 4.18e-141 yagB - - S ko:K06950 - ko00000 phosphohydrolase
NIIKMLNH_00146 3.13e-114 bsaA 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
NIIKMLNH_00147 6.09e-225 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NIIKMLNH_00148 1.28e-276 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
NIIKMLNH_00149 5.12e-42 cspD - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
NIIKMLNH_00150 1.17e-22 degR - - - - - - -
NIIKMLNH_00151 1.05e-40 - - - S - - - Protein of unknown function (DUF2564)
NIIKMLNH_00152 1.54e-37 ypeQ - - S - - - Zinc-finger
NIIKMLNH_00153 2.31e-162 ypeP 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 COG0328 Ribonuclease HI
NIIKMLNH_00154 3.27e-136 ypdP - - S ko:K09125 - ko00000 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NIIKMLNH_00155 6.28e-87 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease
NIIKMLNH_00156 5.23e-05 - - - - ko:K06429 - ko00000 -
NIIKMLNH_00157 2.26e-213 ypcP - - L - - - 5'3' exonuclease
NIIKMLNH_00158 1.08e-11 - - - - - - - -
NIIKMLNH_00159 1.17e-51 ypbS - - S - - - Protein of unknown function (DUF2533)
NIIKMLNH_00160 0.0 ypbR - - S - - - Dynamin family
NIIKMLNH_00161 3.33e-113 ypbQ - - S ko:K16168 - ko00000,ko01008 protein conserved in bacteria
NIIKMLNH_00162 1.52e-264 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
NIIKMLNH_00163 1e-290 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
NIIKMLNH_00164 5.51e-127 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NIIKMLNH_00165 0.0 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
NIIKMLNH_00166 4.09e-224 kdgT - - P ko:K02526 - ko00000,ko02000 The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
NIIKMLNH_00167 1.2e-131 kdgA 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 2-dehydro-3-deoxy-phosphogluconate aldolase
NIIKMLNH_00168 1.15e-236 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0524 Sugar kinases, ribokinase family
NIIKMLNH_00169 7.8e-238 kdgR - - K ko:K02525 - ko00000,ko03000 transcriptional
NIIKMLNH_00170 2.96e-203 kduI 5.3.1.17 - G ko:K01815 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
NIIKMLNH_00171 1.09e-174 kduD 1.1.1.127 - IQ ko:K00065 ko00040,map00040 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NIIKMLNH_00172 0.0 ypvA 3.6.4.12 - KL ko:K03722 - ko00000,ko01000,ko03400 COG1199 Rad3-related DNA helicases
NIIKMLNH_00174 4.71e-285 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
NIIKMLNH_00175 2.97e-60 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NIIKMLNH_00176 4.85e-128 ypsA - - S - - - Belongs to the UPF0398 family
NIIKMLNH_00177 5.92e-300 yprB - - L ko:K07502 - ko00000 RNase_H superfamily
NIIKMLNH_00178 0.0 yprA - - L ko:K06877 - ko00000 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
NIIKMLNH_00179 7.43e-110 ypqE - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 COG2190 Phosphotransferase system IIA components
NIIKMLNH_00180 2.93e-93 hspX - - O ko:K06335,ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
NIIKMLNH_00181 8.72e-68 yppG - - S - - - YppG-like protein
NIIKMLNH_00182 9.21e-11 - - - S - - - YppF-like protein
NIIKMLNH_00183 1.42e-10 yppE - - S - - - Bacterial domain of unknown function (DUF1798)
NIIKMLNH_00186 1.7e-236 yppC - - S - - - Protein of unknown function (DUF2515)
NIIKMLNH_00187 3.2e-150 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NIIKMLNH_00188 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
NIIKMLNH_00189 4.78e-120 ypoC - - - - - - -
NIIKMLNH_00190 3.57e-158 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NIIKMLNH_00191 6.62e-165 dnaD - - L ko:K02086 - ko00000 DNA replication protein DnaD
NIIKMLNH_00192 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 asparaginyl-tRNA
NIIKMLNH_00193 2.53e-284 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
NIIKMLNH_00194 7.61e-102 ypmB - - S - - - protein conserved in bacteria
NIIKMLNH_00195 1.52e-32 ypmA - - S - - - Protein of unknown function (DUF4264)
NIIKMLNH_00196 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
NIIKMLNH_00197 4.16e-85 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NIIKMLNH_00198 3.03e-197 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NIIKMLNH_00199 4.85e-194 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
NIIKMLNH_00200 5.68e-233 birA 6.3.4.15 - K ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NIIKMLNH_00201 1.83e-279 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NIIKMLNH_00202 8.18e-266 bshA - GT4 M ko:K00754 - ko00000,ko01000 N-acetyl-alpha-D-glucosaminyl L-malate synthase
NIIKMLNH_00203 1.89e-166 bshB1 - - S ko:K01463 - ko00000,ko01000 proteins, LmbE homologs
NIIKMLNH_00204 1.03e-92 mgsA 4.2.3.3 - G ko:K01734 ko00640,ko01120,map00640,map01120 ko00000,ko00001,ko01000 methylglyoxal synthase
NIIKMLNH_00205 2.4e-189 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NIIKMLNH_00206 1.01e-73 ypjD - - S - - - Nucleotide pyrophosphohydrolase
NIIKMLNH_00207 3.7e-200 ypjC - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
NIIKMLNH_00208 2.79e-182 ypjB - - S - - - sporulation protein
NIIKMLNH_00209 6.63e-125 ypjA - - S - - - membrane
NIIKMLNH_00210 5.71e-191 qcrC - - C ko:K03888 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Menaquinol-cytochrome c reductase cytochrome b c subunit
NIIKMLNH_00211 8.76e-166 qcrB - - C ko:K03887 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG1290 Cytochrome b subunit of the bc complex
NIIKMLNH_00212 3.35e-126 qcrA - - C ko:K03886 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Menaquinol-cytochrome c reductase
NIIKMLNH_00213 5.55e-100 ypiF - - S - - - Protein of unknown function (DUF2487)
NIIKMLNH_00214 1.29e-129 ypiB - - S - - - Belongs to the UPF0302 family
NIIKMLNH_00215 8.74e-298 ypiA - - S - - - COG0457 FOG TPR repeat
NIIKMLNH_00216 4.03e-301 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
NIIKMLNH_00217 1.21e-264 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
NIIKMLNH_00218 1.24e-256 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NIIKMLNH_00219 2.21e-185 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
NIIKMLNH_00220 4.44e-293 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NIIKMLNH_00221 3.85e-151 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
NIIKMLNH_00222 4.18e-145 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
NIIKMLNH_00223 5e-229 trpD 2.4.2.18, 4.1.3.27 - E ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NIIKMLNH_00224 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NIIKMLNH_00225 9.82e-84 aroH 5.4.99.5 - E ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
NIIKMLNH_00226 3.31e-262 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NIIKMLNH_00227 1.44e-277 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NIIKMLNH_00228 3.03e-182 cheR 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 COG1352 Methylase of chemotaxis methyl-accepting proteins
NIIKMLNH_00229 2.17e-104 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
NIIKMLNH_00230 4.09e-249 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
NIIKMLNH_00231 1.34e-169 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
NIIKMLNH_00232 8.72e-178 hepS 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
NIIKMLNH_00233 5.13e-46 mtrB - - K ko:K06285 - ko00000,ko03000 Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
NIIKMLNH_00234 4.41e-131 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
NIIKMLNH_00235 1.07e-57 hbs - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NIIKMLNH_00236 0.0 spoIVA - - S ko:K06398 - ko00000 ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NIIKMLNH_00237 1.02e-174 yphF - - - - - - -
NIIKMLNH_00238 7.09e-27 yphE - - S - - - Protein of unknown function (DUF2768)
NIIKMLNH_00239 1.05e-229 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
NIIKMLNH_00240 1.72e-315 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
NIIKMLNH_00241 2.06e-38 ypzH - - - - - - -
NIIKMLNH_00242 7.2e-31 yphB - - S ko:K05739 - ko00000 YIEGIA protein
NIIKMLNH_00243 1.98e-156 yphB - - S ko:K05739 - ko00000 YIEGIA protein
NIIKMLNH_00244 4.34e-131 yphA - - - - - - -
NIIKMLNH_00245 1.13e-11 - - - S - - - YpzI-like protein
NIIKMLNH_00246 2.58e-232 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NIIKMLNH_00247 7.8e-262 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
NIIKMLNH_00248 3.91e-144 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
NIIKMLNH_00249 1.39e-29 - - - S - - - Family of unknown function (DUF5359)
NIIKMLNH_00250 1.27e-141 ypfA - - M - - - Flagellar protein YcgR
NIIKMLNH_00251 0.0 ypeB - - H ko:K06313 - ko00000 sporulation protein
NIIKMLNH_00252 6.93e-208 sleB 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Spore cortex-lytic enzyme
NIIKMLNH_00253 4.33e-154 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
NIIKMLNH_00254 7.03e-216 ypdA 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 COG0492 Thioredoxin reductase
NIIKMLNH_00255 1.42e-308 gudB 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
NIIKMLNH_00256 5.56e-136 mecB - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
NIIKMLNH_00257 1.02e-186 ypbG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
NIIKMLNH_00258 8.23e-106 ypbF - - S - - - Protein of unknown function (DUF2663)
NIIKMLNH_00259 8.61e-143 ypbE - - M - - - Lysin motif
NIIKMLNH_00260 3.55e-128 ypbD - - S ko:K07052 - ko00000 metal-dependent membrane protease
NIIKMLNH_00261 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
NIIKMLNH_00262 2.12e-253 ypbB 5.1.3.1 - S ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 protein conserved in bacteria
NIIKMLNH_00263 8.35e-55 fer - - C ko:K05337 - ko00000 Ferredoxin
NIIKMLNH_00264 3.07e-122 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NIIKMLNH_00265 0.0 serA 1.1.1.399, 1.1.1.95 - E ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NIIKMLNH_00266 1.87e-171 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
NIIKMLNH_00267 7.95e-236 rsiX - - - - - - -
NIIKMLNH_00268 1.08e-133 sigX - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NIIKMLNH_00269 0.0 resE 2.7.13.3 - T ko:K07651 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NIIKMLNH_00270 1.69e-171 resD - - T ko:K07775 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NIIKMLNH_00271 4.67e-279 resC - - O - - - 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
NIIKMLNH_00272 0.0 resB - - O ko:K07399 - ko00000 COG1333 ResB protein required for cytochrome c biosynthesis
NIIKMLNH_00273 1.5e-128 resA - - CO - - - Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
NIIKMLNH_00274 3.66e-168 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
NIIKMLNH_00275 8.62e-114 spmB - - S ko:K06374 - ko00000 Spore maturation protein
NIIKMLNH_00276 7.57e-135 spmA - - S ko:K06373 - ko00000 Spore maturation protein
NIIKMLNH_00277 9.67e-272 dacB 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
NIIKMLNH_00278 1.69e-125 ypuI - - S - - - Protein of unknown function (DUF3907)
NIIKMLNH_00279 2e-135 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NIIKMLNH_00280 1.33e-167 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NIIKMLNH_00281 2.06e-119 ypuF - - S ko:K09763 - ko00000 Domain of unknown function (DUF309)
NIIKMLNH_00282 1.12e-83 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NIIKMLNH_00283 8.41e-107 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
NIIKMLNH_00284 3.12e-292 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NIIKMLNH_00285 3.55e-147 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
NIIKMLNH_00286 2.07e-260 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NIIKMLNH_00287 5.98e-72 ypuD - - - - - - -
NIIKMLNH_00288 1.18e-132 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
NIIKMLNH_00289 1.02e-42 ypzJ - - S ko:K07069 - ko00000 nucleic-acid-binding protein containing a Zn-ribbon domain
NIIKMLNH_00291 1.23e-105 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NIIKMLNH_00292 8.93e-192 ypuA - - S - - - Secreted protein
NIIKMLNH_00293 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NIIKMLNH_00294 0.0 spoVAF - - EG ko:K06408 - ko00000 Stage V sporulation protein AF
NIIKMLNH_00295 1.85e-143 - - - S ko:K06407 - ko00000 stage V sporulation protein
NIIKMLNH_00296 2.15e-75 spoVAEB - - S ko:K06407 - ko00000 stage V sporulation protein
NIIKMLNH_00297 6.02e-246 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
NIIKMLNH_00298 6.71e-102 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
NIIKMLNH_00299 5.43e-90 spoVAB - - S ko:K06404 - ko00000 Stage V sporulation protein AB
NIIKMLNH_00300 1.15e-143 spoVAA - - S ko:K06403 - ko00000 Stage V sporulation protein AA
NIIKMLNH_00301 1.18e-174 sigF - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NIIKMLNH_00302 6.78e-100 spoIIAB 2.7.11.1 - F ko:K06379 - ko00000,ko01000 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
NIIKMLNH_00303 3e-76 spoIIAA - - T ko:K06378 - ko00000 Belongs to the anti-sigma-factor antagonist family
NIIKMLNH_00304 5.58e-270 dacF 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
NIIKMLNH_00305 1.39e-190 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NIIKMLNH_00306 2.77e-293 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
NIIKMLNH_00307 3.91e-214 xerD - - L ko:K04763 - ko00000,ko03036 recombinase XerD
NIIKMLNH_00308 2.73e-50 - - - S - - - Protein of unknown function (DUF4227)
NIIKMLNH_00309 2.26e-104 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
NIIKMLNH_00310 1.96e-139 spoIIM - - S ko:K06384 - ko00000 Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
NIIKMLNH_00311 5.16e-34 yqkK - - - - - - -
NIIKMLNH_00312 5.62e-309 mleA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
NIIKMLNH_00313 1.14e-309 mleN - - C ko:K03315 - ko00000,ko02000 Na H antiporter
NIIKMLNH_00314 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Aspartate ammonia-lyase
NIIKMLNH_00315 1.03e-237 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase
NIIKMLNH_00316 3.18e-77 ansR - - K - - - Transcriptional regulator
NIIKMLNH_00317 3.56e-281 yqxK - - L - - - DNA helicase
NIIKMLNH_00318 4.07e-120 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
NIIKMLNH_00319 5.78e-10 - - - S - - - Protein of unknown function (DUF3936)
NIIKMLNH_00320 3.61e-215 yqkF - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
NIIKMLNH_00321 2.28e-25 yqkE - - S - - - Protein of unknown function (DUF3886)
NIIKMLNH_00322 1.61e-222 yqkD - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
NIIKMLNH_00323 1.12e-53 yqkC - - S - - - Protein of unknown function (DUF2552)
NIIKMLNH_00324 6.17e-73 yqkB - - S - - - Belongs to the HesB IscA family
NIIKMLNH_00325 9.27e-248 yqkA - - K - - - GrpB protein
NIIKMLNH_00326 2.25e-78 yqjZ - - S - - - enzyme involved in biosynthesis of extracellular polysaccharides
NIIKMLNH_00327 5.46e-113 yqjY - - K ko:K06977 - ko00000 acetyltransferase
NIIKMLNH_00328 2.18e-53 yqiX - - S - - - YolD-like protein
NIIKMLNH_00329 2.47e-299 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NIIKMLNH_00331 2.01e-285 yqjV - - G - - - Major Facilitator Superfamily
NIIKMLNH_00333 9.03e-94 yqjT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NIIKMLNH_00334 7.68e-23 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
NIIKMLNH_00335 4.05e-157 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
NIIKMLNH_00336 0.0 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
NIIKMLNH_00337 3.98e-184 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
NIIKMLNH_00338 1.33e-228 yqjP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
NIIKMLNH_00339 9.32e-188 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NIIKMLNH_00340 0.0 rocB - - E - - - arginine degradation protein
NIIKMLNH_00341 1.72e-245 namA 1.6.99.1 - C ko:K00354 - ko00000,ko01000 Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
NIIKMLNH_00342 3.17e-187 yqjL - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NIIKMLNH_00343 8.59e-27 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
NIIKMLNH_00344 2.2e-221 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NIIKMLNH_00345 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NIIKMLNH_00346 0.0 gnd 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NIIKMLNH_00347 6.41e-300 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NIIKMLNH_00348 1.77e-32 yqzJ - - - - - - -
NIIKMLNH_00349 2.53e-156 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NIIKMLNH_00350 7.46e-176 yqjF - - S ko:K09166 - ko00000 Uncharacterized conserved protein (COG2071)
NIIKMLNH_00351 5.26e-259 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 COG2195 Di- and tripeptidases
NIIKMLNH_00352 0.0 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
NIIKMLNH_00353 1.9e-94 mce 5.1.99.1 - E ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0346 Lactoylglutathione lyase and related lyases
NIIKMLNH_00355 2.32e-126 yqjB - - S - - - protein conserved in bacteria
NIIKMLNH_00356 4.95e-221 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
NIIKMLNH_00357 5.2e-166 artM 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
NIIKMLNH_00358 8.94e-143 artQ - - E ko:K02029 - ko00000,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
NIIKMLNH_00359 1.43e-175 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
NIIKMLNH_00360 3.79e-101 yqiW - - S - - - Belongs to the UPF0403 family
NIIKMLNH_00361 9.96e-213 bmrU - - I - - - COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NIIKMLNH_00362 3.6e-266 norA - - EGP ko:K08153,ko:K19576,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
NIIKMLNH_00363 6.38e-195 - - - K ko:K19575 - ko00000,ko00002,ko03000 helix_turn_helix, mercury resistance
NIIKMLNH_00364 3.77e-288 bkdB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NIIKMLNH_00365 6.92e-235 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NIIKMLNH_00366 1.11e-237 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NIIKMLNH_00367 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NIIKMLNH_00368 1.18e-255 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Belongs to the acetokinase family
NIIKMLNH_00369 1.92e-262 ldh 1.4.1.9 - E ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
NIIKMLNH_00370 6.35e-201 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 phosphate butyryltransferase
NIIKMLNH_00371 0.0 bkdR - - KT - - - Transcriptional regulator
NIIKMLNH_00372 1.56e-46 yqzF - - S - - - Protein of unknown function (DUF2627)
NIIKMLNH_00373 1.52e-209 prpB 4.1.3.30, 5.4.2.9 - G ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
NIIKMLNH_00374 0.0 prpD 4.2.1.79 - S ko:K01720 ko00640,map00640 ko00000,ko00001,ko01000 2-methylcitrate dehydratase
NIIKMLNH_00375 2.94e-261 mmgD 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
NIIKMLNH_00376 4.95e-268 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
NIIKMLNH_00377 2.31e-197 mmgB 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
NIIKMLNH_00378 1.1e-278 mmgA 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
NIIKMLNH_00379 3.39e-168 yqiK 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
NIIKMLNH_00380 1.63e-138 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Cell wall hydrolase autolysin
NIIKMLNH_00381 4.74e-37 - - - - - - - -
NIIKMLNH_00382 5.68e-273 yqiG - - C - - - COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
NIIKMLNH_00384 5.43e-186 spo0A - - KT ko:K07699 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
NIIKMLNH_00385 2.96e-302 spoIVB 3.4.21.116 - M ko:K06399 - ko00000,ko01000,ko01002 Stage IV sporulation protein B
NIIKMLNH_00386 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
NIIKMLNH_00387 8.85e-102 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
NIIKMLNH_00388 2.93e-197 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 rRNA methylase
NIIKMLNH_00389 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NIIKMLNH_00390 3.45e-208 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
NIIKMLNH_00391 1.09e-51 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NIIKMLNH_00392 3.55e-312 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NIIKMLNH_00393 4.34e-200 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NIIKMLNH_00394 4.8e-86 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NIIKMLNH_00395 1.65e-88 yqhY - - S - - - protein conserved in bacteria
NIIKMLNH_00396 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
NIIKMLNH_00397 3.21e-93 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NIIKMLNH_00398 9.92e-135 spoIIIAH - - S ko:K06397 - ko00000 SpoIIIAH-like protein
NIIKMLNH_00399 9.25e-150 spoIIIAG - - S ko:K06396 - ko00000 stage III sporulation protein AG
NIIKMLNH_00400 1.28e-131 spoIIIAF - - S ko:K06395 - ko00000 Stage III sporulation protein AF (Spore_III_AF)
NIIKMLNH_00401 7.65e-257 spoIIIAE - - S ko:K06394 - ko00000 stage III sporulation protein AE
NIIKMLNH_00402 1.93e-77 spoIIIAD - - S ko:K06393 - ko00000 Stage III sporulation protein AD
NIIKMLNH_00403 1.63e-39 spoIIIAC - - S ko:K06392 - ko00000 stage III sporulation protein AC
NIIKMLNH_00404 3.29e-110 spoIIIAB - - S ko:K06391 - ko00000 Stage III sporulation protein
NIIKMLNH_00405 8.22e-217 spoIIIAA - - S ko:K06390 - ko00000 stage III sporulation protein AA
NIIKMLNH_00406 6.96e-50 yqhV - - S - - - Protein of unknown function (DUF2619)
NIIKMLNH_00407 4.8e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NIIKMLNH_00408 2.99e-249 yqhT 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
NIIKMLNH_00409 1.94e-100 aroQ 4.2.1.10 - E ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a trans-dehydration via an enolate intermediate
NIIKMLNH_00410 8.02e-121 yqhR - - S - - - Conserved membrane protein YqhR
NIIKMLNH_00411 6.02e-220 yqhQ - - S - - - Protein of unknown function (DUF1385)
NIIKMLNH_00412 5.18e-81 yqhP - - - - - - -
NIIKMLNH_00413 1.21e-210 yqhO - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
NIIKMLNH_00414 1.97e-97 mntR - - K ko:K03709 - ko00000,ko03000 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
NIIKMLNH_00415 3.73e-203 lipM 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
NIIKMLNH_00416 7.5e-83 yqhL - - P - - - COG0607 Rhodanese-related sulfurtransferase
NIIKMLNH_00417 4.74e-163 gcvPB 1.4.4.2 - E ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NIIKMLNH_00418 3.95e-168 gcvPB 1.4.4.2 - E ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NIIKMLNH_00419 0.0 gcvPA 1.4.4.2 - E ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NIIKMLNH_00420 3.31e-262 gcvT 2.1.2.10 - E ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
NIIKMLNH_00421 0.0 yqhH - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
NIIKMLNH_00422 1.77e-194 yqhG - - S - - - Bacterial protein YqhG of unknown function
NIIKMLNH_00423 1.39e-33 sinI - - S ko:K06372 - ko00000 Anti-repressor SinI
NIIKMLNH_00424 3.69e-72 sinR - - K ko:K19449 - ko00000,ko03000 transcriptional
NIIKMLNH_00425 3.14e-182 tasA_1 - - S ko:K06336 - ko00000,ko01002 Cell division protein FtsN
NIIKMLNH_00426 7.4e-98 sipW 3.4.21.89 - U ko:K13280 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase
NIIKMLNH_00427 5.16e-152 yqxM - - - ko:K19433 - ko00000 -
NIIKMLNH_00428 4.33e-69 yqzG - - S - - - Protein of unknown function (DUF3889)
NIIKMLNH_00429 4.9e-37 yqzE - - S - - - YqzE-like protein
NIIKMLNH_00430 3.78e-57 - - - S ko:K02249 - ko00000,ko00002,ko02044 ComG operon protein 7
NIIKMLNH_00431 7.11e-47 comGF - - U ko:K02246,ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
NIIKMLNH_00432 2.08e-77 comGE - - - ko:K02247 - ko00000,ko00002,ko02044 -
NIIKMLNH_00433 1.49e-88 gspH - - NU ko:K02246,ko:K02457,ko:K02459,ko:K02672,ko:K08084,ko:K10926 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02035,ko02044 protein transport across the cell outer membrane
NIIKMLNH_00434 5.33e-63 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
NIIKMLNH_00435 1.44e-217 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 COG1459 Type II secretory pathway, component PulF
NIIKMLNH_00436 5.23e-256 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NIIKMLNH_00437 0.000111 - - - S - - - Domain in cystathionine beta-synthase and other proteins.
NIIKMLNH_00438 7.17e-232 yqxL - - P - - - Mg2 transporter protein
NIIKMLNH_00439 2.86e-305 yqhB - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
NIIKMLNH_00440 6.84e-190 yqhA - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NIIKMLNH_00442 7.79e-85 yqgZ 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
NIIKMLNH_00443 1.46e-50 yqgY - - S - - - Protein of unknown function (DUF2626)
NIIKMLNH_00444 1.52e-155 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
NIIKMLNH_00445 1.91e-31 yqgW - - S - - - Protein of unknown function (DUF2759)
NIIKMLNH_00446 7.65e-66 yqgV - - S - - - Thiamine-binding protein
NIIKMLNH_00447 2.69e-256 yqgU - - - - - - -
NIIKMLNH_00448 1.69e-280 yqgT 3.4.19.11 - E ko:K01308 - ko00000,ko01000,ko01002 Gamma-D-glutamyl-L-diamino acid endopeptidase
NIIKMLNH_00449 0.0 yqgS 2.7.8.20 - M ko:K01138,ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
NIIKMLNH_00450 2.31e-230 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
NIIKMLNH_00451 1.27e-43 yqgQ - - S - - - Protein conserved in bacteria
NIIKMLNH_00452 0.0 gluP 3.4.21.105 - O ko:K19225 - ko00000,ko01000,ko01002 membrane protein (homolog of Drosophila rhomboid)
NIIKMLNH_00453 3.38e-14 yqgO - - - - - - -
NIIKMLNH_00454 3.25e-136 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NIIKMLNH_00455 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
NIIKMLNH_00456 1.74e-251 yqgM 2.4.1.250 - M ko:K15521 - ko00000,ko01000 Glycosyl transferases group 1
NIIKMLNH_00458 2.81e-67 yqzD - - - - - - -
NIIKMLNH_00459 2.92e-98 yqzC - - S - - - YceG-like family
NIIKMLNH_00460 1.57e-186 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NIIKMLNH_00461 9.78e-190 pstBA 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NIIKMLNH_00462 3.55e-200 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
NIIKMLNH_00463 7.11e-203 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
NIIKMLNH_00464 6.14e-204 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
NIIKMLNH_00465 0.0 pbpA - - M ko:K21465,ko:K21466 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
NIIKMLNH_00466 1.46e-216 yqgE - - EGP ko:K08222 - ko00000,ko02000 Major facilitator superfamily
NIIKMLNH_00467 1.06e-41 yqgE - - EGP ko:K08222 - ko00000,ko02000 Major facilitator superfamily
NIIKMLNH_00468 1.59e-148 sodA 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
NIIKMLNH_00469 8.25e-101 yqgC - - S ko:K09793 - ko00000 protein conserved in bacteria
NIIKMLNH_00470 7.62e-171 yqgB - - S - - - Protein of unknown function (DUF1189)
NIIKMLNH_00471 8.33e-99 yqgA - - - - - - -
NIIKMLNH_00472 1.35e-61 yqfZ - - M ko:K06417 - ko00000 LysM domain
NIIKMLNH_00473 5.22e-257 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NIIKMLNH_00474 2.04e-81 yqfX - - S - - - membrane
NIIKMLNH_00475 1.37e-140 yqfW - - S ko:K05967 - ko00000 Belongs to the 5'(3')-deoxyribonucleotidase family
NIIKMLNH_00476 4.98e-106 zur - - P ko:K02076 - ko00000,ko03000 Belongs to the Fur family
NIIKMLNH_00477 3.83e-199 yqfU - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
NIIKMLNH_00478 3.01e-49 yqfT - - S - - - Protein of unknown function (DUF2624)
NIIKMLNH_00479 1.04e-214 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NIIKMLNH_00480 1.09e-310 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NIIKMLNH_00481 1.14e-53 yqfQ - - S - - - YqfQ-like protein
NIIKMLNH_00482 1.75e-226 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NIIKMLNH_00483 1.08e-268 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NIIKMLNH_00484 1.63e-148 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
NIIKMLNH_00485 1.61e-81 cccA - - C ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
NIIKMLNH_00486 2.79e-254 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NIIKMLNH_00487 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NIIKMLNH_00488 6.03e-114 yqxD - - S ko:K09768 - ko00000 Belongs to the UPF0178 family
NIIKMLNH_00489 6.38e-191 yqfL 2.7.11.33, 2.7.4.28 - S ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
NIIKMLNH_00490 3.29e-144 ccpN - - K - - - CBS domain
NIIKMLNH_00491 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
NIIKMLNH_00492 2.12e-222 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
NIIKMLNH_00493 7.48e-187 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
NIIKMLNH_00494 5.29e-27 - - - S - - - YqzL-like protein
NIIKMLNH_00495 9.98e-215 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NIIKMLNH_00496 6.71e-93 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
NIIKMLNH_00497 4.75e-80 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
NIIKMLNH_00498 8.68e-106 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NIIKMLNH_00499 0.0 yqfF - - S ko:K07037 - ko00000 membrane-associated HD superfamily hydrolase
NIIKMLNH_00501 4.99e-224 phoH - - T ko:K06217 - ko00000 Phosphate starvation-inducible protein PhoH
NIIKMLNH_00502 1.04e-242 yqfD - - S ko:K06438 - ko00000 Stage IV sporulation
NIIKMLNH_00503 2.07e-60 yqfC - - S - - - sporulation protein YqfC
NIIKMLNH_00504 5.2e-78 yqfB - - - - - - -
NIIKMLNH_00505 4.35e-192 yqfA - - S - - - UPF0365 protein
NIIKMLNH_00506 2.66e-290 yqeZ - - O ko:K07403 - ko00000 COG1030 Membrane-bound serine protease (ClpP class)
NIIKMLNH_00507 2.25e-90 yqeY - - S ko:K09117 - ko00000 Yqey-like protein
NIIKMLNH_00508 1.03e-26 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
NIIKMLNH_00509 3.26e-201 yqeW - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
NIIKMLNH_00510 0.0 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 ribosomal protein S12 methylthiotransferase
NIIKMLNH_00511 3.96e-178 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NIIKMLNH_00512 2.2e-223 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
NIIKMLNH_00513 3.41e-257 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NIIKMLNH_00514 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
NIIKMLNH_00515 4.36e-116 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NIIKMLNH_00516 1.65e-241 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NIIKMLNH_00517 2.9e-276 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
NIIKMLNH_00518 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NIIKMLNH_00519 1.43e-69 yqxA - - S - - - Protein of unknown function (DUF3679)
NIIKMLNH_00520 2.73e-283 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
NIIKMLNH_00521 1.39e-257 gpr 3.4.24.78 - C ko:K06012 - ko00000,ko01000,ko01002 Initiates the rapid degradation of small, acid-soluble proteins during spore germination
NIIKMLNH_00522 4e-49 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
NIIKMLNH_00523 2.35e-243 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
NIIKMLNH_00524 2.36e-22 - - - S - - - YqzM-like protein
NIIKMLNH_00525 6.83e-188 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
NIIKMLNH_00526 3.4e-299 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
NIIKMLNH_00527 2.67e-136 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
NIIKMLNH_00528 1.5e-134 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
NIIKMLNH_00529 1.1e-188 comER - - E ko:K02239 - ko00000,ko00002,ko02044 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NIIKMLNH_00530 6.62e-177 yqeM - - Q - - - Methyltransferase
NIIKMLNH_00531 1.39e-81 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NIIKMLNH_00532 3.95e-132 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
NIIKMLNH_00533 4.99e-141 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NIIKMLNH_00534 8.95e-61 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein containing KH domain, possibly ribosomal protein
NIIKMLNH_00535 8.1e-199 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NIIKMLNH_00536 9.65e-273 yqeH - - S ko:K06948 - ko00000,ko03009 In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
NIIKMLNH_00537 2.17e-123 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
NIIKMLNH_00539 3.71e-181 yqeF - - E - - - GDSL-like Lipase/Acylhydrolase
NIIKMLNH_00540 5.03e-178 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
NIIKMLNH_00541 3.81e-134 yqeD - - S - - - SNARE associated Golgi protein
NIIKMLNH_00542 2.45e-213 yqeC 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconate dehydrogenase
NIIKMLNH_00543 1.49e-167 - - - - - - - -
NIIKMLNH_00544 2.53e-97 nucB - - M - - - Deoxyribonuclease NucA/NucB
NIIKMLNH_00545 1.1e-72 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NIIKMLNH_00546 0.0 - - - L ko:K06400 - ko00000 Recombinase
NIIKMLNH_00548 7.33e-81 - - - - - - - -
NIIKMLNH_00549 6e-77 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
NIIKMLNH_00550 2.02e-05 pyrE_1 - - S - - - phosphoribosyltransferase
NIIKMLNH_00552 7.66e-07 nt5e 3.1.3.18 - F ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score
NIIKMLNH_00553 7.02e-119 - - - S - - - Tetratricopeptide repeat
NIIKMLNH_00556 0.0 - - - A ko:K21491 - ko00000,ko01000,ko02048 Pre-toxin TG
NIIKMLNH_00557 3.77e-133 - - - S ko:K21492 - ko00000,ko02048 Suppressor of fused protein (SUFU)
NIIKMLNH_00558 8.84e-68 - - - S - - - Immunity protein 50
NIIKMLNH_00560 2.19e-90 yokH - - G - - - SMI1 / KNR4 family
NIIKMLNH_00561 9.58e-71 - - - V - - - HNH endonuclease
NIIKMLNH_00562 1.62e-169 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
NIIKMLNH_00563 6.87e-88 - - - S - - - Bacteriophage holin family
NIIKMLNH_00564 1.4e-203 xepA - - - - - - -
NIIKMLNH_00565 1.45e-27 - - - - - - - -
NIIKMLNH_00566 7.41e-57 xkdW - - S - - - XkdW protein
NIIKMLNH_00567 2.24e-207 - - - - - - - -
NIIKMLNH_00568 7.09e-53 - - - - - - - -
NIIKMLNH_00569 2.74e-126 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
NIIKMLNH_00570 9.48e-239 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
NIIKMLNH_00571 3.14e-89 xkdS - - S - - - Protein of unknown function (DUF2634)
NIIKMLNH_00572 2.34e-50 xkdR - - S - - - Protein of unknown function (DUF2577)
NIIKMLNH_00573 7.68e-227 xkdQ - - G - - - NLP P60 protein
NIIKMLNH_00574 1.5e-150 xkdP - - S - - - Lysin motif
NIIKMLNH_00575 0.0 xkdO - - L - - - Transglycosylase SLT domain
NIIKMLNH_00576 8.84e-89 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
NIIKMLNH_00578 4.23e-99 xkdM - - S - - - Phage tail tube protein
NIIKMLNH_00579 0.0 xkdK - - S - - - Phage tail sheath C-terminal domain
NIIKMLNH_00580 8.49e-35 - - - - - - - -
NIIKMLNH_00581 4.26e-98 yqbJ - - - - - - -
NIIKMLNH_00582 6.48e-115 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
NIIKMLNH_00583 4.44e-79 yqbH - - S - - - Domain of unknown function (DUF3599)
NIIKMLNH_00584 4.1e-87 - - - S - - - Protein of unknown function (DUF3199)
NIIKMLNH_00585 6.56e-64 - - - S - - - YqbF, hypothetical protein domain
NIIKMLNH_00586 7.57e-215 xkdG - - S - - - Phage capsid family
NIIKMLNH_00587 2.84e-163 yqbD - - L - - - Putative phage serine protease XkdF
NIIKMLNH_00589 6.36e-188 - - - S - - - Phage Mu protein F like protein
NIIKMLNH_00590 0.0 yqbA - - S - - - portal protein
NIIKMLNH_00591 1.62e-313 yqaT - - S ko:K06909 - ko00000 phage terminase, large subunit
NIIKMLNH_00592 1.06e-111 yqaS - - L - - - DNA packaging
NIIKMLNH_00593 5.57e-86 - - - S - - - Region found in RelA / SpoT proteins
NIIKMLNH_00597 4.59e-10 - - - - - - - -
NIIKMLNH_00598 5.72e-99 yqaQ - - L - - - Transposase
NIIKMLNH_00599 5.99e-52 - - - D - - - nuclear chromosome segregation
NIIKMLNH_00600 5.65e-42 yqaO - - S - - - Phage-like element PBSX protein XtrA
NIIKMLNH_00601 1.28e-93 rusA - - L - - - Endodeoxyribonuclease RusA
NIIKMLNH_00603 6.38e-180 yqaM - - L - - - IstB-like ATP binding protein
NIIKMLNH_00604 5.07e-154 yqaL - - L - - - DnaD domain protein
NIIKMLNH_00605 6.85e-193 recT - - L ko:K07455 - ko00000,ko03400 RecT family
NIIKMLNH_00606 2.03e-223 yqaJ - - L - - - YqaJ-like viral recombinase domain
NIIKMLNH_00610 1.04e-133 - - - - - - - -
NIIKMLNH_00612 1.57e-47 - - - K - - - Helix-turn-helix XRE-family like proteins
NIIKMLNH_00613 1.25e-74 - - - K - - - sequence-specific DNA binding
NIIKMLNH_00614 2.93e-11 - - - S - - - Protein of unknown function (DUF4064)
NIIKMLNH_00615 4.53e-122 xkdA - - E - - - IrrE N-terminal-like domain
NIIKMLNH_00616 4.46e-79 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NIIKMLNH_00617 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NIIKMLNH_00618 1.14e-197 yybE - - K - - - Transcriptional regulator
NIIKMLNH_00619 2.12e-197 ydhE - - CG - - - UDP-glucoronosyl and UDP-glucosyl transferase
NIIKMLNH_00620 2.15e-90 psiE - - S ko:K13256 - ko00000 Protein PsiE homolog
NIIKMLNH_00621 2.45e-304 yrkQ - - T - - - Histidine kinase
NIIKMLNH_00622 8.35e-163 yrkP - - T ko:K02483 - ko00000,ko02022 Transcriptional regulator
NIIKMLNH_00623 3.06e-282 yrkO - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
NIIKMLNH_00624 5.41e-134 yrkN - - K - - - Acetyltransferase (GNAT) family
NIIKMLNH_00625 5.71e-126 yrkL - - S ko:K11748 - ko00000,ko02000 Flavodoxin-like fold
NIIKMLNH_00626 9.36e-104 - - - S - - - Protein of unknown function with HXXEE motif
NIIKMLNH_00627 6.63e-162 yrkJ - - S ko:K07090 - ko00000 membrane transporter protein
NIIKMLNH_00628 6.46e-49 yrkI - - O - - - Belongs to the sulfur carrier protein TusA family
NIIKMLNH_00629 8.57e-272 yrkH - - P - - - Rhodanese Homology Domain
NIIKMLNH_00630 5.84e-129 yrkF - - OP - - - Belongs to the sulfur carrier protein TusA family
NIIKMLNH_00631 1.88e-106 yrkE - - O - - - DsrE/DsrF/DrsH-like family
NIIKMLNH_00632 4.38e-52 yrkD - - S - - - protein conserved in bacteria
NIIKMLNH_00633 1.9e-27 - - - - - - - -
NIIKMLNH_00634 1.28e-137 yrkC - - G - - - Cupin domain
NIIKMLNH_00635 1.24e-194 bltR - - K - - - helix_turn_helix, mercury resistance
NIIKMLNH_00636 2.17e-268 blt - - EGP ko:K08153,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
NIIKMLNH_00637 2.16e-108 bltD 2.3.1.57 - K ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 FR47-like protein
NIIKMLNH_00638 3.27e-294 yrkA - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
NIIKMLNH_00639 7.04e-23 - - - S - - - YrzO-like protein
NIIKMLNH_00640 4.91e-216 yrdR - - EG - - - EamA-like transporter family
NIIKMLNH_00641 1.64e-202 - - - K - - - Transcriptional regulator
NIIKMLNH_00642 1.01e-252 trkA - - P ko:K07222 - ko00000 Oxidoreductase
NIIKMLNH_00643 2.64e-215 czcD - - P ko:K16264 - ko00000,ko02000 COG1230 Co Zn Cd efflux system component
NIIKMLNH_00644 7.09e-292 brnQ - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
NIIKMLNH_00645 1.97e-66 azlD - - E - - - Branched-chain amino acid transport protein (AzlD)
NIIKMLNH_00646 6.57e-176 azlC - - E - - - AzlC protein
NIIKMLNH_00647 4.82e-103 bkdR - - K - - - helix_turn_helix ASNC type
NIIKMLNH_00648 2.19e-289 cypA 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
NIIKMLNH_00649 2.11e-130 yrdC - - Q - - - Isochorismatase family
NIIKMLNH_00650 1.04e-71 - - - S - - - Protein of unknown function (DUF2568)
NIIKMLNH_00651 2.06e-11 M1-394 - - S - - - Domain of unknown function (DUF4280)
NIIKMLNH_00652 2.14e-53 - - - - - - - -
NIIKMLNH_00653 8.53e-120 yrdA - - S - - - DinB family
NIIKMLNH_00654 8.54e-212 aadK - - G ko:K05593 - ko00000,ko01000,ko01504 Streptomycin adenylyltransferase
NIIKMLNH_00655 5.15e-247 npd 1.13.12.16 - S ko:K00459 ko00910,map00910 ko00000,ko00001,ko01000 COG2070 Dioxygenases related to 2-nitropropane dioxygenase
NIIKMLNH_00656 3.98e-187 murI 5.1.1.3 - M ko:K01776 ko00471,ko01100,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
NIIKMLNH_00657 2.39e-162 yrpD - - S - - - Domain of unknown function, YrpD
NIIKMLNH_00658 8.53e-166 zinT - - S ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
NIIKMLNH_00659 3.7e-123 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NIIKMLNH_00660 4.9e-239 yrpG - - C - - - Aldo/keto reductase family
NIIKMLNH_00661 5.91e-283 yraO - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
NIIKMLNH_00662 2.97e-210 yraN - - K - - - Transcriptional regulator
NIIKMLNH_00663 3.85e-259 yraM - - S - - - PrpF protein
NIIKMLNH_00664 2.57e-192 csn 3.2.1.132 - M ko:K01233 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
NIIKMLNH_00665 5.07e-56 yraL - - S - - - COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NIIKMLNH_00666 1.02e-192 - - - S - - - Alpha beta hydrolase
NIIKMLNH_00667 1.33e-79 - - - T - - - sh3 domain protein
NIIKMLNH_00668 2.92e-81 - - - T - - - sh3 domain protein
NIIKMLNH_00669 5.06e-87 - - - E - - - Glyoxalase-like domain
NIIKMLNH_00670 4.19e-50 yraG - - - ko:K06440 - ko00000 -
NIIKMLNH_00671 9.61e-84 yraF - - M - - - Spore coat protein
NIIKMLNH_00672 3.41e-279 adhB 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
NIIKMLNH_00673 1.23e-35 yraE - - - ko:K06440 - ko00000 -
NIIKMLNH_00674 7.23e-66 yraD - - M ko:K06439 - ko00000 Spore coat protein
NIIKMLNH_00675 3.17e-68 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
NIIKMLNH_00676 4.53e-33 yphJ 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 peroxiredoxin activity
NIIKMLNH_00677 2.78e-252 adhA - - C ko:K13979 - ko00000,ko01000 alcohol dehydrogenase
NIIKMLNH_00678 1.58e-116 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
NIIKMLNH_00679 0.0 sacC 3.2.1.80 - G ko:K03332 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
NIIKMLNH_00680 1.39e-192 levG - - G ko:K02771,ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
NIIKMLNH_00681 6.11e-168 levF - - G ko:K02746,ko:K02795,ko:K11196 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
NIIKMLNH_00682 7.63e-107 ptnA 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11195 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system mannose fructose sorbose family
NIIKMLNH_00683 2.66e-97 levD 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11194 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
NIIKMLNH_00684 0.0 levR - - K - - - PTS system fructose IIA component
NIIKMLNH_00685 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
NIIKMLNH_00686 5.63e-137 yrhP - - E - - - LysE type translocator
NIIKMLNH_00687 5.66e-192 yrhO - - K - - - Archaeal transcriptional regulator TrmB
NIIKMLNH_00688 9.97e-114 sigV - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NIIKMLNH_00689 1.01e-190 rsiV - - S - - - Protein of unknown function (DUF3298)
NIIKMLNH_00690 0.0 oatA - - I - - - Acyltransferase family
NIIKMLNH_00691 6.32e-59 yrhK - - S - - - YrhK-like protein
NIIKMLNH_00692 0.0 yrhJ 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
NIIKMLNH_00693 2.26e-135 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
NIIKMLNH_00694 1.05e-124 yrhH - - Q - - - methyltransferase
NIIKMLNH_00695 9.39e-08 - - - S - - - Probable sporulation protein (Bac_small_yrzI)
NIIKMLNH_00697 1.38e-183 yrhG - - P ko:K21993 - ko00000,ko02000 Formate nitrite
NIIKMLNH_00698 4.41e-80 yrhF - - S - - - Uncharacterized conserved protein (DUF2294)
NIIKMLNH_00699 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
NIIKMLNH_00700 6.05e-103 yrhD - - S - - - Protein of unknown function (DUF1641)
NIIKMLNH_00701 6.93e-49 yrhC - - S - - - YrhC-like protein
NIIKMLNH_00702 4.95e-268 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
NIIKMLNH_00703 1.36e-215 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Cysteine synthase
NIIKMLNH_00704 5.64e-161 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NIIKMLNH_00705 3.44e-153 yrrT - - Q ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Could be a S-adenosyl-L-methionine-dependent methyltransferase
NIIKMLNH_00706 4.94e-36 yrzA - - S - - - Protein of unknown function (DUF2536)
NIIKMLNH_00707 8.2e-102 yrrS - - S - - - Protein of unknown function (DUF1510)
NIIKMLNH_00708 0.0 pbpI - - M ko:K21468 - ko00000,ko01011 Penicillin-binding Protein
NIIKMLNH_00709 1.14e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NIIKMLNH_00710 4.51e-148 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
NIIKMLNH_00711 4.62e-313 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 COG0826 Collagenase and related proteases
NIIKMLNH_00712 1.09e-222 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
NIIKMLNH_00713 6.92e-155 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-methyltransferase
NIIKMLNH_00714 2.15e-241 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NIIKMLNH_00715 2.94e-60 yrzB - - S - - - Belongs to the UPF0473 family
NIIKMLNH_00716 5.49e-93 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NIIKMLNH_00717 2.22e-55 yrzL - - S - - - Belongs to the UPF0297 family
NIIKMLNH_00718 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NIIKMLNH_00719 4.26e-25 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NIIKMLNH_00720 3.07e-242 yrrI - - S - - - AI-2E family transporter
NIIKMLNH_00721 1.28e-167 glnQ - - E ko:K09972,ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
NIIKMLNH_00722 1.01e-184 glnH - - ET ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
NIIKMLNH_00723 3.24e-139 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NIIKMLNH_00724 2.18e-138 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NIIKMLNH_00725 5.38e-12 - - - S - - - Protein of unknown function (DUF3918)
NIIKMLNH_00726 8.4e-42 yrzR - - - - - - -
NIIKMLNH_00727 1.44e-107 yrrD - - S - - - protein conserved in bacteria
NIIKMLNH_00728 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NIIKMLNH_00729 1.01e-20 yrrB - - S - - - COG0457 FOG TPR repeat
NIIKMLNH_00730 1.62e-278 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NIIKMLNH_00731 3.63e-270 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
NIIKMLNH_00732 8.12e-93 cymR - - K ko:K17472 - ko00000,ko03000 Transcriptional regulator
NIIKMLNH_00733 6.98e-303 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
NIIKMLNH_00734 2.29e-176 yrvM - - H ko:K22132 - ko00000,ko03016 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
NIIKMLNH_00735 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NIIKMLNH_00736 3e-310 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
NIIKMLNH_00738 0.0 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG3103 SH3 domain protein
NIIKMLNH_00739 1.36e-90 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NIIKMLNH_00740 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NIIKMLNH_00741 2.53e-118 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NIIKMLNH_00742 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
NIIKMLNH_00743 1.07e-64 yrvD - - S - - - Lipopolysaccharide assembly protein A domain
NIIKMLNH_00744 4.94e-109 trkA1 - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
NIIKMLNH_00745 0.0 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NIIKMLNH_00746 5.53e-65 yrzD - - S - - - Post-transcriptional regulator
NIIKMLNH_00747 0.0 spoVB - - S ko:K06409 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NIIKMLNH_00748 5.83e-143 yrbG - - S - - - membrane
NIIKMLNH_00749 1.46e-96 yrzE - - S - - - Protein of unknown function (DUF3792)
NIIKMLNH_00750 1.24e-52 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit YajC
NIIKMLNH_00751 2.74e-291 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NIIKMLNH_00752 7.04e-247 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NIIKMLNH_00753 2.91e-30 yrzS - - S - - - Protein of unknown function (DUF2905)
NIIKMLNH_00754 9.14e-239 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NIIKMLNH_00755 2.84e-137 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NIIKMLNH_00756 6.46e-121 bofC - - S ko:K06318 - ko00000 BofC C-terminal domain
NIIKMLNH_00757 0.0 csbX - - EGP - - - the major facilitator superfamily
NIIKMLNH_00758 4.59e-247 idhA 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, NAD-binding Rossmann fold
NIIKMLNH_00759 1.91e-151 yrzF - - T - - - serine threonine protein kinase
NIIKMLNH_00761 4.45e-68 - - - S - - - Family of unknown function (DUF5412)
NIIKMLNH_00762 0.0 yrbD - - E ko:K03310 - ko00000 Sodium alanine symporter
NIIKMLNH_00763 8.63e-165 yebC - - K - - - transcriptional regulatory protein
NIIKMLNH_00764 2.55e-70 - - - S ko:K06345 - ko00000 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NIIKMLNH_00765 5.7e-216 safA - - M ko:K06370 - ko00000 spore coat assembly protein SafA
NIIKMLNH_00766 1.04e-268 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NIIKMLNH_00767 2.41e-200 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
NIIKMLNH_00768 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
NIIKMLNH_00769 1.17e-290 nifS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
NIIKMLNH_00770 1.01e-122 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
NIIKMLNH_00771 1.43e-208 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
NIIKMLNH_00772 4.75e-96 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
NIIKMLNH_00773 1.6e-307 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NIIKMLNH_00774 4.25e-139 spo0B - - T ko:K06375 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Sporulation initiation phospho-transferase B, C-terminal
NIIKMLNH_00775 2.7e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
NIIKMLNH_00776 2.66e-74 ysxB - - J ko:K07584 - ko00000 ribosomal protein
NIIKMLNH_00777 6.34e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
NIIKMLNH_00778 3.74e-208 spoIVFB - - S ko:K06402 - ko00000,ko01000,ko01002 Stage IV sporulation protein
NIIKMLNH_00779 5.24e-187 spoIVFA - - M ko:K06401 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
NIIKMLNH_00780 6.84e-185 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
NIIKMLNH_00781 4.3e-158 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
NIIKMLNH_00782 8.72e-111 mreD - - M ko:K03571 - ko00000,ko03036 shape-determining protein
NIIKMLNH_00783 7.78e-202 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
NIIKMLNH_00784 5.26e-235 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein MreB
NIIKMLNH_00785 8.35e-163 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
NIIKMLNH_00786 7.06e-132 maf - - D ko:K06287 - ko00000 septum formation protein Maf
NIIKMLNH_00787 1.23e-210 spoIIB - - S ko:K06380 - ko00000 Sporulation related domain
NIIKMLNH_00788 3.08e-162 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
NIIKMLNH_00789 1.55e-315 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
NIIKMLNH_00790 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NIIKMLNH_00791 1.53e-35 - - - - - - - -
NIIKMLNH_00792 1.96e-251 ysxE - - S - - - A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NIIKMLNH_00793 0.0 spoVID - - M ko:K06417 - ko00000 stage VI sporulation protein D
NIIKMLNH_00794 3.53e-312 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
NIIKMLNH_00795 2.14e-232 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the ALAD family
NIIKMLNH_00796 1.01e-183 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
NIIKMLNH_00797 5.15e-219 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
NIIKMLNH_00798 6.56e-187 hemX - - O ko:K02497 - ko00000 cytochrome C
NIIKMLNH_00799 2.74e-315 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NIIKMLNH_00800 4.77e-116 ysxD - - - - - - -
NIIKMLNH_00801 7.6e-139 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
NIIKMLNH_00802 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NIIKMLNH_00803 0.0 lonB 3.4.21.53 - LO ko:K04076 - ko00000,ko01000,ko01002 Belongs to the peptidase S16 family
NIIKMLNH_00804 1.15e-296 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NIIKMLNH_00805 8.87e-287 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NIIKMLNH_00806 1.25e-236 ysoA - - H - - - Tetratricopeptide repeat
NIIKMLNH_00807 4.4e-149 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NIIKMLNH_00808 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NIIKMLNH_00809 3.53e-254 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
NIIKMLNH_00810 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NIIKMLNH_00811 5.55e-244 ilvC 1.1.1.86 - EH ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NIIKMLNH_00812 5.05e-110 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
NIIKMLNH_00813 0.0 ilvB 2.2.1.6 - E ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
NIIKMLNH_00815 2.83e-99 ysnE - - K ko:K03829 - ko00000,ko01000 acetyltransferase
NIIKMLNH_00816 1.11e-203 - - - N - - - domain, Protein
NIIKMLNH_00817 3.36e-181 ysnF - - S - - - protein conserved in bacteria
NIIKMLNH_00819 4.05e-119 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
NIIKMLNH_00820 7.86e-132 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NIIKMLNH_00821 2.04e-170 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NIIKMLNH_00822 5.65e-256 gerM - - S ko:K06298 - ko00000 COG5401 Spore germination protein
NIIKMLNH_00823 4.49e-194 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
NIIKMLNH_00824 1.6e-98 ysmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
NIIKMLNH_00825 1.81e-41 gerE - - K ko:K01994 - ko00000,ko03000 Transcriptional regulator
NIIKMLNH_00826 3.1e-101 ysmA - - S ko:K07107 - ko00000,ko01000 thioesterase
NIIKMLNH_00827 1.15e-189 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
NIIKMLNH_00828 0.0 sdhA 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
NIIKMLNH_00829 1.35e-140 sdhC - - C ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 succinate dehydrogenase
NIIKMLNH_00830 8.53e-104 yslB - - S - - - Protein of unknown function (DUF2507)
NIIKMLNH_00831 4.83e-276 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
NIIKMLNH_00832 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NIIKMLNH_00833 1.12e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
NIIKMLNH_00834 0.0 xsa 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
NIIKMLNH_00836 2.89e-226 etfA - - C ko:K03522 - ko00000,ko04147 Electron transfer flavoprotein
NIIKMLNH_00837 2.58e-179 etfB - - C ko:K03521 - ko00000 Electron transfer flavoprotein
NIIKMLNH_00838 6.3e-176 fadB 4.2.1.17 - I ko:K13767 ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the enoyl-CoA hydratase isomerase family
NIIKMLNH_00839 5.74e-129 fadR - - K ko:K13770 - ko00000,ko03000 Transcriptional regulator
NIIKMLNH_00840 0.0 lcfA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
NIIKMLNH_00841 3.76e-89 yshE - - S ko:K08989 - ko00000 membrane
NIIKMLNH_00842 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NIIKMLNH_00843 0.0 polX - - L ko:K02347 - ko00000,ko03400 COG1796 DNA polymerase IV (family X)
NIIKMLNH_00844 1.09e-111 yshB - - S - - - membrane protein, required for colicin V production
NIIKMLNH_00845 1.04e-54 zapA - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NIIKMLNH_00846 8.48e-215 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NIIKMLNH_00847 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NIIKMLNH_00848 1.81e-250 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NIIKMLNH_00849 3.13e-171 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NIIKMLNH_00850 4.37e-43 sspI - - S ko:K06426 - ko00000 Belongs to the SspI family
NIIKMLNH_00851 1.45e-259 cdaR_1 - - KT ko:K02647 - ko00000,ko03000 regulator
NIIKMLNH_00852 0.0 glcD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Glycolate oxidase subunit
NIIKMLNH_00853 0.0 glcF - - C ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 Glycolate oxidase
NIIKMLNH_00854 1.26e-69 - 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase-like domain
NIIKMLNH_00855 0.0 cstA - - T ko:K06200 - ko00000 Carbon starvation protein
NIIKMLNH_00856 0.0 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 alpha-L-arabinofuranosidase activity
NIIKMLNH_00857 4.28e-190 araQ - - G ko:K17236 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport system permease
NIIKMLNH_00858 1.94e-218 araP - - G ko:K17235 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
NIIKMLNH_00859 4.59e-81 araN - - G ko:K17234 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
NIIKMLNH_00860 2.42e-218 araN - - G ko:K17234 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
NIIKMLNH_00861 2.24e-283 araM 1.1.1.261 - I ko:K00096 ko00564,map00564 ko00000,ko00001,ko01000 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
NIIKMLNH_00862 4.98e-186 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
NIIKMLNH_00863 1.7e-170 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
NIIKMLNH_00864 0.0 araB 2.7.1.16 - C ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Belongs to the ribulokinase family
NIIKMLNH_00865 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
NIIKMLNH_00866 5.74e-241 - 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
NIIKMLNH_00867 4.35e-262 ysdC - - G - - - COG1363 Cellulase M and related proteins
NIIKMLNH_00868 2.29e-88 ysdB - - S - - - Sigma-w pathway protein YsdB
NIIKMLNH_00869 1.27e-59 ysdA - - S - - - Membrane
NIIKMLNH_00870 3.26e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NIIKMLNH_00871 3.93e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
NIIKMLNH_00872 1.81e-111 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NIIKMLNH_00874 5.34e-150 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
NIIKMLNH_00875 4.9e-84 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
NIIKMLNH_00876 1.96e-166 lytT - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
NIIKMLNH_00877 9.44e-139 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NIIKMLNH_00878 1.03e-237 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NIIKMLNH_00879 1.98e-189 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
NIIKMLNH_00880 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NIIKMLNH_00882 3.46e-205 ytxC - - S - - - YtxC-like family
NIIKMLNH_00883 1.33e-141 ytxB - - S - - - SNARE associated Golgi protein
NIIKMLNH_00884 1.22e-220 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
NIIKMLNH_00885 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 Membrane attachment protein
NIIKMLNH_00886 2.42e-105 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NIIKMLNH_00887 2.42e-88 speH 4.1.1.50 - E ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
NIIKMLNH_00888 1.22e-246 gapB 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NIIKMLNH_00889 9.85e-88 ytcD - - K - - - Transcriptional regulator
NIIKMLNH_00890 4.78e-256 ytbD - - EGP ko:K19577 - ko00000,ko02000 -transporter
NIIKMLNH_00891 4.54e-205 ytbE - - S - - - reductase
NIIKMLNH_00892 2.82e-126 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NIIKMLNH_00893 1.68e-138 ytaF - - P - - - Probably functions as a manganese efflux pump
NIIKMLNH_00894 2.34e-201 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NIIKMLNH_00895 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NIIKMLNH_00896 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
NIIKMLNH_00897 1.62e-169 phoP - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NIIKMLNH_00898 1.04e-217 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible oxidation of malate to oxaloacetate
NIIKMLNH_00899 9.27e-309 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 isocitrate
NIIKMLNH_00900 1.17e-267 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
NIIKMLNH_00901 9.38e-95 ytwI - - S - - - membrane
NIIKMLNH_00902 2.73e-245 ytvI - - S - - - sporulation integral membrane protein YtvI
NIIKMLNH_00903 3.16e-80 fxsA - - S ko:K07113 - ko00000 COG3030 Protein affecting phage T7 exclusion by the F plasmid
NIIKMLNH_00904 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
NIIKMLNH_00905 4.65e-229 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NIIKMLNH_00906 9.82e-234 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
NIIKMLNH_00907 1.46e-206 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NIIKMLNH_00908 8.53e-287 ytsJ 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
NIIKMLNH_00909 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
NIIKMLNH_00910 2.45e-75 ytrH - - S - - - Sporulation protein YtrH
NIIKMLNH_00911 5.07e-96 ytrI - - - - - - -
NIIKMLNH_00912 1.15e-39 - - - - - - - -
NIIKMLNH_00913 3.55e-230 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 COG0618 Exopolyphosphatase-related proteins
NIIKMLNH_00914 2.15e-63 ytpI - - S - - - YtpI-like protein
NIIKMLNH_00915 1.13e-308 ytoI - - K - - - transcriptional regulator containing CBS domains
NIIKMLNH_00916 1.45e-202 ytnM - - S ko:K07090 - ko00000 membrane transporter protein
NIIKMLNH_00917 1.72e-305 hipO2 - - E ko:K01436,ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
NIIKMLNH_00918 4.66e-164 - 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin kinase
NIIKMLNH_00919 0.0 ytnJ - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NIIKMLNH_00920 1.51e-62 ytnI - - O - - - COG0695 Glutaredoxin and related proteins
NIIKMLNH_00921 7.2e-236 ytmO - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NIIKMLNH_00922 6.61e-183 tcyN - - E ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
NIIKMLNH_00923 4.76e-155 - - - U ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NIIKMLNH_00924 1.66e-157 ytmL - - P ko:K16958,ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NIIKMLNH_00925 3.84e-192 tcyK - - M ko:K16957 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
NIIKMLNH_00926 1.02e-191 - - - ET ko:K16956,ko:K16957,ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
NIIKMLNH_00927 2.81e-128 ytmI - - K ko:K00680 - ko00000,ko01000 Acetyltransferase (GNAT) domain
NIIKMLNH_00928 9.66e-221 ytlI - - K ko:K21960 - ko00000,ko03000 LysR substrate binding domain
NIIKMLNH_00929 3.19e-166 ytkL - - S - - - Belongs to the UPF0173 family
NIIKMLNH_00930 2.81e-182 ytkK 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NIIKMLNH_00932 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
NIIKMLNH_00933 1.06e-297 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
NIIKMLNH_00934 9.5e-114 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
NIIKMLNH_00935 4.69e-281 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NIIKMLNH_00936 3.78e-224 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
NIIKMLNH_00937 1.93e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NIIKMLNH_00938 1.06e-94 ytfJ - - S - - - Sporulation protein YtfJ
NIIKMLNH_00939 2.79e-147 ytfI - - S - - - Protein of unknown function (DUF2953)
NIIKMLNH_00940 2.36e-111 yteJ - - S - - - RDD family
NIIKMLNH_00941 8.34e-231 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA
NIIKMLNH_00942 1.39e-188 nadK2 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NIIKMLNH_00943 0.0 ytcJ - - S - - - amidohydrolase
NIIKMLNH_00944 0.0 ytcI 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
NIIKMLNH_00945 2.12e-40 - - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
NIIKMLNH_00946 6.26e-289 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NIIKMLNH_00947 1.59e-265 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
NIIKMLNH_00948 1.17e-304 braB - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
NIIKMLNH_00949 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NIIKMLNH_00950 5.29e-198 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 COG1387 Histidinol phosphatase and related hydrolases of the PHP family
NIIKMLNH_00951 2.94e-142 yttP - - K - - - Transcriptional regulator
NIIKMLNH_00952 1.95e-114 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
NIIKMLNH_00953 0.0 ytrP - - T - - - COG2199 FOG GGDEF domain
NIIKMLNH_00954 2.01e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NIIKMLNH_00956 5.31e-303 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NIIKMLNH_00957 0.0 acsA 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
NIIKMLNH_00958 2.84e-155 acuA - - K ko:K04766 - ko00000,ko01000 Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
NIIKMLNH_00959 6.16e-152 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
NIIKMLNH_00960 1.49e-289 acuC - - BQ ko:K04768 - ko00000 histone deacetylase
NIIKMLNH_00961 1.6e-161 ytxE - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
NIIKMLNH_00962 6.84e-187 motP - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
NIIKMLNH_00963 4.16e-235 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
NIIKMLNH_00964 7.64e-250 aroA 2.5.1.54, 5.4.99.5 - E ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
NIIKMLNH_00965 1.51e-69 ytxJ - - O - - - Protein of unknown function (DUF2847)
NIIKMLNH_00966 3.17e-30 ytxH - - S - - - COG4980 Gas vesicle protein
NIIKMLNH_00967 1.67e-63 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NIIKMLNH_00968 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
NIIKMLNH_00969 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
NIIKMLNH_00970 1.78e-140 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NIIKMLNH_00971 1.02e-191 ytpQ - - S - - - Belongs to the UPF0354 family
NIIKMLNH_00972 3.17e-75 ytpP - - CO - - - Thioredoxin
NIIKMLNH_00973 7.02e-103 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
NIIKMLNH_00974 2.15e-260 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
NIIKMLNH_00975 1.17e-67 ytzB - - S - - - small secreted protein
NIIKMLNH_00976 0.0 malS 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
NIIKMLNH_00977 3.07e-193 ytnP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
NIIKMLNH_00978 5.09e-155 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NIIKMLNH_00979 9.51e-61 ytzH - - S - - - YtzH-like protein
NIIKMLNH_00980 3.02e-192 ytmP - - M - - - Phosphotransferase
NIIKMLNH_00981 0.0 amyX 3.2.1.41 CBM48,GH13 G ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
NIIKMLNH_00982 2.22e-231 ytlR - - I - - - Diacylglycerol kinase catalytic domain
NIIKMLNH_00983 4.92e-212 ytlQ - - - - - - -
NIIKMLNH_00984 2.38e-127 ytlP 3.1.4.58 - J ko:K01975 - ko00000,ko01000,ko03016 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
NIIKMLNH_00985 3e-221 ytkP 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
NIIKMLNH_00986 0.0 ytjP 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Dipeptidase
NIIKMLNH_00987 1.73e-288 pbuO - - S ko:K06901 - ko00000,ko02000 permease
NIIKMLNH_00988 1.94e-252 ythQ - - U ko:K01992 - ko00000,ko00002,ko02000 Bacterial ABC transporter protein EcsB
NIIKMLNH_00989 9.39e-167 ythP - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
NIIKMLNH_00990 4.46e-46 ytzE - - K - - - COG1349 Transcriptional regulators of sugar metabolism
NIIKMLNH_00991 2.13e-169 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
NIIKMLNH_00992 0.0 ytgP - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NIIKMLNH_00993 3.87e-291 ytfP - - S ko:K07007 - ko00000 HI0933-like protein
NIIKMLNH_00994 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
NIIKMLNH_00995 2.14e-36 yteV - - S - - - Sporulation protein Cse60
NIIKMLNH_00996 1.05e-147 yteU - - S - - - Integral membrane protein
NIIKMLNH_00997 0.0 yteT - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
NIIKMLNH_00998 3.92e-93 yteS - - G - - - transport
NIIKMLNH_00999 7.4e-147 yteR 3.2.1.172 GH105 G ko:K15532 - ko00000,ko01000 unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
NIIKMLNH_01000 3.4e-100 yteR 3.2.1.172 GH105 G ko:K15532 - ko00000,ko01000 unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
NIIKMLNH_01001 1.31e-220 lplB13 - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
NIIKMLNH_01002 0.0 ytdP - - K - - - Transcriptional regulator
NIIKMLNH_01003 0.0 - - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
NIIKMLNH_01004 6.19e-193 ytcP - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
NIIKMLNH_01005 2.21e-178 ytbQ 1.1.1.203, 1.1.1.388 - GM ko:K18981,ko:K19243 ko00030,ko00053,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00053,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 NAD dependent epimerase/dehydratase family
NIIKMLNH_01006 4.5e-279 bioI 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
NIIKMLNH_01007 4.57e-244 bioB 2.8.1.6 - H ko:K01012 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NIIKMLNH_01008 2.68e-159 bioD 6.3.3.3 - H ko:K01935 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NIIKMLNH_01009 2.58e-275 bioF 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
NIIKMLNH_01010 0.0 bioA 2.6.1.105, 2.6.1.62 - H ko:K00833,ko:K19563 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
NIIKMLNH_01011 2.24e-179 bioW 6.2.1.14 - H ko:K01906 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
NIIKMLNH_01012 1.13e-219 - - - S - - - Acetyl xylan esterase (AXE1)
NIIKMLNH_01013 1.78e-241 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
NIIKMLNH_01014 1.17e-308 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
NIIKMLNH_01015 1.66e-214 amyD - - P ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NIIKMLNH_01016 7.65e-186 amyC - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
NIIKMLNH_01017 0.0 melA 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
NIIKMLNH_01018 1.22e-68 ytwF - - P - - - Sulfurtransferase
NIIKMLNH_01019 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
NIIKMLNH_01020 3.63e-72 ytvB - - S - - - Protein of unknown function (DUF4257)
NIIKMLNH_01021 1.56e-182 pfyP - - T - - - Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
NIIKMLNH_01022 7.01e-268 yttB - - EGP - - - Major facilitator superfamily
NIIKMLNH_01023 3.78e-76 yttA - - S - - - Pfam Transposase IS66
NIIKMLNH_01024 0.0 bceB - - V ko:K11632,ko:K19080 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter (permease)
NIIKMLNH_01025 3.14e-178 bceA - - V ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter, ATP-binding protein
NIIKMLNH_01026 8.4e-235 bceS 2.7.13.3 - T ko:K11629,ko:K19077 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 His Kinase A (phosphoacceptor) domain
NIIKMLNH_01027 1.46e-166 graR - - T ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01504,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NIIKMLNH_01028 1.39e-296 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
NIIKMLNH_01029 5.88e-163 ytrE - - V ko:K16920 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NIIKMLNH_01030 3.13e-161 - - - - ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
NIIKMLNH_01031 9.47e-190 - - - P ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
NIIKMLNH_01032 5.96e-207 ytrB - - P ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NIIKMLNH_01033 2.68e-87 ytrA - - K ko:K07979 - ko00000,ko03000 GntR family transcriptional regulator
NIIKMLNH_01035 1.27e-55 ytzC - - S - - - Protein of unknown function (DUF2524)
NIIKMLNH_01036 1.93e-243 ytqA - - S ko:K07139 - ko00000 Fe-S oxidoreductase
NIIKMLNH_01037 4.57e-135 ytqB - - J - - - Putative rRNA methylase
NIIKMLNH_01038 4.81e-276 ytpB 4.2.3.130 - S ko:K16188 - ko00000,ko01000 Tetraprenyl-beta-curcumene synthase
NIIKMLNH_01039 4.7e-192 ytpA 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Alpha beta hydrolase
NIIKMLNH_01040 8.35e-88 ytoA - - S - - - COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NIIKMLNH_01041 0.0 ytnA - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
NIIKMLNH_01042 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
NIIKMLNH_01043 9.2e-286 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NIIKMLNH_01044 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
NIIKMLNH_01045 2.34e-51 ytmB - - S - - - Protein of unknown function (DUF2584)
NIIKMLNH_01046 7.79e-190 ytmA - - E - - - COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
NIIKMLNH_01047 1.87e-240 ytlA - - P ko:K02051 - ko00000,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
NIIKMLNH_01048 3.03e-184 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
NIIKMLNH_01049 1.32e-183 ytlD - - P ko:K02050 - ko00000,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
NIIKMLNH_01050 4.47e-113 ytkD 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
NIIKMLNH_01051 3.2e-81 ytkC - - S - - - Bacteriophage holin family
NIIKMLNH_01052 1.8e-99 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
NIIKMLNH_01054 4.78e-95 ytkA - - S - - - YtkA-like
NIIKMLNH_01055 8.36e-113 luxS 4.4.1.21 - T ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NIIKMLNH_01056 1.27e-133 ytiB 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
NIIKMLNH_01057 1.44e-55 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
NIIKMLNH_01058 8.73e-315 ythA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
NIIKMLNH_01059 1.64e-238 ythB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG1294 Cytochrome bd-type quinol oxidase, subunit 2
NIIKMLNH_01060 2.43e-34 - - - S - - - Domain of Unknown Function (DUF1540)
NIIKMLNH_01061 9.24e-192 mntD - - P ko:K11709,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
NIIKMLNH_01062 6.11e-295 mntC - - P ko:K11705,ko:K11708,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
NIIKMLNH_01063 3.97e-175 mntB 3.6.3.35 - P ko:K02074,ko:K09820,ko:K11710,ko:K19973 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
NIIKMLNH_01064 3.77e-217 troA - - P ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
NIIKMLNH_01065 4.09e-272 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
NIIKMLNH_01066 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
NIIKMLNH_01067 3.45e-200 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NIIKMLNH_01068 9.85e-197 menH 4.2.99.20 - S ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
NIIKMLNH_01069 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NIIKMLNH_01070 0.0 menF 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
NIIKMLNH_01071 8.68e-169 yteA - - T - - - COG1734 DnaK suppressor protein
NIIKMLNH_01072 9.99e-119 ytdA 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
NIIKMLNH_01073 1.32e-306 ytcA 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NIIKMLNH_01074 4.12e-226 ytcB - - M - - - NAD-dependent epimerase dehydratase
NIIKMLNH_01075 6.86e-296 - - - M ko:K06338 - ko00000 Glycosyltransferase Family 4
NIIKMLNH_01077 2.82e-262 cotS - - S ko:K06337 - ko00000 Seems to be required for the assembly of the CotSA protein in spores
NIIKMLNH_01078 1.18e-274 cotSA - - M ko:K06338 - ko00000 Glycosyl transferases group 1
NIIKMLNH_01079 1.29e-260 cotI - - S ko:K06331 - ko00000 Spore coat protein
NIIKMLNH_01080 1.9e-99 ytaB - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 membrane
NIIKMLNH_01081 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NIIKMLNH_01082 0.0 glgA 2.4.1.21 GT5 G ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
NIIKMLNH_01083 3.72e-238 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Glucose-1-phosphate adenylyltransferase, GlgD subunit
NIIKMLNH_01084 8.49e-265 glgC 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NIIKMLNH_01085 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NIIKMLNH_01107 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
NIIKMLNH_01108 2.52e-122 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
NIIKMLNH_01109 9.87e-122 - - - M - - - FR47-like protein
NIIKMLNH_01110 4.54e-258 yuaG - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 protein conserved in bacteria
NIIKMLNH_01111 1.68e-109 yuaF - - OU - - - Membrane protein implicated in regulation of membrane protease activity
NIIKMLNH_01112 1.95e-109 yuaE - - S - - - DinB superfamily
NIIKMLNH_01113 1.17e-136 yuaD - - - - - - -
NIIKMLNH_01114 4.26e-292 gbsB 1.1.1.1 - C ko:K11440 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
NIIKMLNH_01115 0.0 gbsA 1.2.1.8 - C ko:K00130 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
NIIKMLNH_01116 2.39e-121 yuaC - - K ko:K22109 - ko00000,ko03000 Belongs to the GbsR family
NIIKMLNH_01117 5.83e-118 yuaB - - - - - - -
NIIKMLNH_01118 1.06e-156 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
NIIKMLNH_01119 4.17e-298 - - - P ko:K03498 - ko00000,ko02000 Potassium
NIIKMLNH_01120 3.31e-52 yubF - - S - - - yiaA/B two helix domain
NIIKMLNH_01121 2.18e-195 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NIIKMLNH_01122 0.0 yubD - - P - - - Major Facilitator Superfamily
NIIKMLNH_01123 2.29e-112 cdoA 1.13.11.20 - S ko:K00456 ko00270,ko00430,ko01100,map00270,map00430,map01100 ko00000,ko00001,ko01000 Cysteine dioxygenase type I
NIIKMLNH_01125 1.73e-182 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NIIKMLNH_01126 8.95e-255 yubA - - S - - - transporter activity
NIIKMLNH_01127 7.48e-235 yulF - - S ko:K22230 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
NIIKMLNH_01128 9.8e-317 rhaA 2.7.1.5, 5.3.1.14 - G ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Belongs to the rhamnose isomerase family
NIIKMLNH_01129 2.86e-72 rhaM 5.1.3.32 - G ko:K03534 - ko00000,ko01000 Involved in the anomeric conversion of L-rhamnose
NIIKMLNH_01130 0.0 rhaB 2.7.1.5 - G ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
NIIKMLNH_01131 1.42e-172 yulB - - K ko:K02530,ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
NIIKMLNH_01132 0.0 yuxG - - IQ - - - Class II Aldolase and Adducin N-terminal domain
NIIKMLNH_01133 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
NIIKMLNH_01134 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
NIIKMLNH_01135 1.81e-299 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
NIIKMLNH_01136 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
NIIKMLNH_01137 6.15e-181 tgl 2.3.2.13 - H ko:K00686 - ko00000,ko01000 Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
NIIKMLNH_01138 5e-48 - - - - - - - -
NIIKMLNH_01139 3.63e-95 yugU - - S - - - Uncharacterised protein family UPF0047
NIIKMLNH_01140 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
NIIKMLNH_01141 8.8e-301 yugS - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
NIIKMLNH_01142 4.8e-150 yugP - - S ko:K06973 - ko00000 Zn-dependent protease
NIIKMLNH_01143 1.58e-50 - - - - - - - -
NIIKMLNH_01144 5.01e-69 mstX - - S - - - Membrane-integrating protein Mistic
NIIKMLNH_01145 3.56e-233 yugO - - P ko:K10716 - ko00000,ko02000 COG1226 Kef-type K transport systems
NIIKMLNH_01146 4.22e-95 yugN - - S - - - YugN-like family
NIIKMLNH_01148 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
NIIKMLNH_01149 9.22e-290 yugK - - C ko:K19955 - ko00000,ko01000 Dehydrogenase
NIIKMLNH_01150 2.85e-287 yugJ - - C ko:K19955 - ko00000,ko01000 oxidoreductases, Fe-dependent alcohol dehydrogenase family
NIIKMLNH_01151 2.21e-46 yuzA - - S ko:K09779 - ko00000 Domain of unknown function (DUF378)
NIIKMLNH_01152 5e-83 yugI - - J ko:K07570,ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
NIIKMLNH_01153 5.43e-255 yugH - - E ko:K10907 - ko00000,ko01000,ko01007 Aminotransferase
NIIKMLNH_01154 6.74e-112 alaR - - K - - - Transcriptional regulator
NIIKMLNH_01155 5.86e-76 yugF - - I - - - Hydrolase
NIIKMLNH_01156 1.28e-104 yugF - - I - - - Hydrolase
NIIKMLNH_01157 8.84e-52 yugE - - S - - - Domain of unknown function (DUF1871)
NIIKMLNH_01158 3.46e-288 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
NIIKMLNH_01159 1.18e-293 kinB2 2.7.13.3 - T ko:K07697 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NIIKMLNH_01160 2.49e-91 kapB - - G ko:K06347 ko02020,map02020 ko00000,ko00001 Kinase associated protein B
NIIKMLNH_01161 6.98e-149 kapD - - L ko:K06348 - ko00000 the KinA pathway to sporulation
NIIKMLNH_01163 8.9e-242 yuxJ - - EGP - - - Major facilitator superfamily
NIIKMLNH_01164 0.0 pbpD 2.4.1.129, 3.4.16.4 GT51 M ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin-binding Protein
NIIKMLNH_01165 1.92e-97 yuxK - - S - - - protein conserved in bacteria
NIIKMLNH_01166 4.19e-113 yufK - - S - - - Family of unknown function (DUF5366)
NIIKMLNH_01167 0.0 malK 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
NIIKMLNH_01168 3.26e-162 dcuR - - T ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
NIIKMLNH_01169 8.14e-252 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
NIIKMLNH_01170 0.0 yufO 3.6.3.17 - S ko:K02056 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NIIKMLNH_01171 6.39e-237 yufP - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
NIIKMLNH_01172 2.43e-215 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
NIIKMLNH_01173 7.99e-309 malP - - C ko:K11616 ko02020,map02020 ko00000,ko00001 COG3493 Na citrate symporter
NIIKMLNH_01174 1.73e-22 - - - - - - - -
NIIKMLNH_01175 0.0 mrpA - - CP ko:K05565 - ko00000,ko02000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
NIIKMLNH_01176 7.66e-91 mrpB - - P ko:K05566 - ko00000,ko02000 Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NIIKMLNH_01177 1.72e-66 mrpC - - P ko:K05567 - ko00000,ko02000 Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NIIKMLNH_01178 0.0 mrpD - - CP ko:K05568 - ko00000,ko02000 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NIIKMLNH_01179 2.12e-102 mrpE - - P ko:K05569 - ko00000,ko02000 Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NIIKMLNH_01180 2.23e-51 mrpF - - P ko:K05570 - ko00000,ko02000 Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NIIKMLNH_01181 5.97e-79 mrpG - - P ko:K05571 - ko00000,ko02000 COG1320 Multisubunit Na H antiporter, MnhG subunit
NIIKMLNH_01182 1.11e-82 yuxO - - Q - - - protein, possibly involved in aromatic compounds catabolism
NIIKMLNH_01183 2.06e-150 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NIIKMLNH_01184 0.0 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NIIKMLNH_01186 5.4e-164 comQ - - H ko:K02251 ko02024,map02024 ko00000,ko00001,ko02044 Belongs to the FPP GGPP synthase family
NIIKMLNH_01187 6.29e-10 - - - S - - - DegQ (SacQ) family
NIIKMLNH_01188 4.38e-09 yuzC - - - - - - -
NIIKMLNH_01189 2.92e-298 yuxH - - T - - - signal transduction protein containing EAL and modified HD-GYP domains
NIIKMLNH_01190 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NIIKMLNH_01191 3.27e-134 pncA - - Q ko:K16788 - ko00000,ko02000 COG1335 Amidases related to nicotinamidase
NIIKMLNH_01192 8.92e-87 - - - S - - - Protein of unknown function (DUF1694)
NIIKMLNH_01193 2.05e-45 yueH - - S - - - YueH-like protein
NIIKMLNH_01194 7.15e-43 yueG - - S ko:K06299 - ko00000 Spore germination protein gerPA/gerPF
NIIKMLNH_01195 1.35e-244 yueF - - S - - - transporter activity
NIIKMLNH_01196 6.59e-92 - - - S - - - Protein of unknown function (DUF2283)
NIIKMLNH_01197 8.4e-33 - - - S - - - Protein of unknown function (DUF2642)
NIIKMLNH_01198 7.78e-125 yueE - - S ko:K06950 - ko00000 phosphohydrolase
NIIKMLNH_01199 5.85e-169 yueD 1.1.1.320 - IQ ko:K16216 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NIIKMLNH_01200 1.78e-96 yueC - - S - - - Family of unknown function (DUF5383)
NIIKMLNH_01201 0.0 yueB - - S - - - type VII secretion protein EsaA
NIIKMLNH_01202 0.0 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
NIIKMLNH_01203 8.62e-271 essB - - S - - - WXG100 protein secretion system (Wss), protein YukC
NIIKMLNH_01204 1.93e-54 yukD - - S - - - WXG100 protein secretion system (Wss), protein YukD
NIIKMLNH_01205 3.93e-60 yukE - - S - - - Belongs to the WXG100 family
NIIKMLNH_01206 4.7e-289 yukF - - QT - - - Transcriptional regulator
NIIKMLNH_01207 1.64e-261 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
NIIKMLNH_01208 1.2e-168 yukJ - - S - - - Uncharacterized conserved protein (DUF2278)
NIIKMLNH_01209 2.02e-47 mbtH - - S ko:K05375 ko00261,ko01130,map00261,map01130 ko00000,ko00001,ko00002 MbtH-like protein
NIIKMLNH_01210 0.0 dhbF - - Q ko:K04780 ko01053,map01053 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NIIKMLNH_01211 6.35e-228 dhbB 3.3.2.1, 6.3.2.14 - Q ko:K01252 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 Isochorismatase family
NIIKMLNH_01212 0.0 entE 2.7.7.58, 6.3.2.14 - Q ko:K02363,ko:K04783 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 2,3-dihydroxybenzoate-AMP ligase
NIIKMLNH_01213 3.34e-287 dhbC 5.4.4.2 - HQ ko:K02361 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
NIIKMLNH_01214 5.83e-178 dhbA 1.3.1.28 - IQ ko:K00216 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
NIIKMLNH_01215 8.58e-211 eSD - - S ko:K07017 - ko00000 Putative esterase
NIIKMLNH_01216 3.92e-156 yuiH - - S - - - Oxidoreductase molybdopterin binding domain
NIIKMLNH_01217 7.98e-123 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Biotin biosynthesis protein
NIIKMLNH_01218 3.65e-279 yuiF - - S ko:K07084 - ko00000,ko02000 antiporter
NIIKMLNH_01219 0.0 pepA 3.4.11.1 - E ko:K01255 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NIIKMLNH_01220 8.63e-102 yuiD - - S ko:K09775 - ko00000 protein conserved in bacteria
NIIKMLNH_01221 1.5e-149 yuiC - - S - - - protein conserved in bacteria
NIIKMLNH_01222 9.78e-47 yuiB - - S - - - Putative membrane protein
NIIKMLNH_01223 4.16e-301 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
NIIKMLNH_01224 1.16e-240 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 reductase
NIIKMLNH_01226 3.7e-234 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NIIKMLNH_01227 1.16e-148 paiB - - K ko:K07734 - ko00000,ko03000 Putative FMN-binding domain
NIIKMLNH_01228 3.98e-115 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NIIKMLNH_01229 6.81e-83 erpA - - S ko:K13628 - ko00000,ko03016 Belongs to the HesB IscA family
NIIKMLNH_01230 4.55e-207 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NIIKMLNH_01231 3.61e-269 yutK - - F ko:K03317 - ko00000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NIIKMLNH_01232 1.74e-52 yuzB - - S - - - Belongs to the UPF0349 family
NIIKMLNH_01233 1.12e-253 yutJ 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
NIIKMLNH_01234 2.7e-74 yuzD - - S - - - protein conserved in bacteria
NIIKMLNH_01235 1.26e-47 yutI - - O - - - COG0694 Thioredoxin-like proteins and domains
NIIKMLNH_01236 0.0 yuxL 3.4.19.1 - EU ko:K01303 - ko00000,ko01000,ko01002 peptidase
NIIKMLNH_01237 2.11e-220 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NIIKMLNH_01238 3.97e-252 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NIIKMLNH_01239 2.76e-306 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
NIIKMLNH_01240 8.97e-253 yutH - - S - - - Spore coat protein
NIIKMLNH_01241 2.26e-101 yutG 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
NIIKMLNH_01242 3.69e-183 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NIIKMLNH_01243 1.96e-98 yutE - - S - - - Protein of unknown function DUF86
NIIKMLNH_01244 3.2e-63 yutD - - S - - - protein conserved in bacteria
NIIKMLNH_01245 2.71e-144 yutC - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NIIKMLNH_01246 1.37e-215 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NIIKMLNH_01247 2.66e-252 lytH - - M ko:K21472 - ko00000,ko01000,ko01002,ko01011 Peptidase, M23
NIIKMLNH_01248 3.49e-169 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
NIIKMLNH_01249 1.39e-64 yunC - - S - - - Domain of unknown function (DUF1805)
NIIKMLNH_01250 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
NIIKMLNH_01251 6.51e-181 yunE - - S ko:K07090 - ko00000 membrane transporter protein
NIIKMLNH_01252 4.26e-220 yunF - - S - - - Protein of unknown function DUF72
NIIKMLNH_01253 3.06e-79 yunG - - - - - - -
NIIKMLNH_01254 0.0 allB 3.5.2.5 - F ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
NIIKMLNH_01255 0.0 pucR - - QT ko:K09684 - ko00000,ko03000 COG2508 Regulator of polyketide synthase expression
NIIKMLNH_01256 8.96e-293 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 Permease family
NIIKMLNH_01257 2.73e-284 pbuX - - F ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
NIIKMLNH_01258 0.0 - 1.7.3.3, 4.1.1.97 - Q ko:K16838 ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
NIIKMLNH_01259 2.09e-72 pucM 3.5.2.17 - S ko:K07127 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
NIIKMLNH_01260 0.000108 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
NIIKMLNH_01261 1.64e-120 - 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03518 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
NIIKMLNH_01262 0.0 pucD 1.17.1.4 - C ko:K00087 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
NIIKMLNH_01263 7.39e-189 pucC 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03519 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
NIIKMLNH_01264 7.22e-142 pucB 1.17.1.4, 2.7.7.76 - S ko:K00087,ko:K07141 ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120 ko00000,ko00001,ko00002,ko01000 MobA-like NTP transferase domain
NIIKMLNH_01265 5.06e-234 pucA 1.17.1.4 - O ko:K00087,ko:K07402 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
NIIKMLNH_01266 3.18e-301 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
NIIKMLNH_01267 8.34e-295 pucF 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
NIIKMLNH_01268 4.42e-216 bsn - - L - - - Ribonuclease
NIIKMLNH_01269 1.2e-262 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NIIKMLNH_01270 1.89e-169 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
NIIKMLNH_01271 2.23e-198 - 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
NIIKMLNH_01272 1.6e-215 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
NIIKMLNH_01273 3.54e-199 yurN - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NIIKMLNH_01274 1.66e-306 yurO - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
NIIKMLNH_01275 5.27e-235 frlB - - M ko:K10708 - ko00000,ko01000 Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
NIIKMLNH_01276 1.71e-87 yurQ - - L - - - COG0322 Nuclease subunit of the excinuclease complex
NIIKMLNH_01277 2.93e-207 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
NIIKMLNH_01278 3.31e-36 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
NIIKMLNH_01280 3.35e-56 - - - - - - - -
NIIKMLNH_01281 5.06e-86 yurT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NIIKMLNH_01282 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 FeS cluster assembly
NIIKMLNH_01283 6.26e-101 nifU - - C ko:K04488 - ko00000 COG0822 NifU homolog involved in Fe-S cluster formation
NIIKMLNH_01284 1.14e-298 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NIIKMLNH_01285 7.12e-311 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
NIIKMLNH_01286 4.46e-182 sufC - - O ko:K09013 - ko00000,ko02000 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
NIIKMLNH_01287 1.56e-80 yurZ - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NIIKMLNH_01288 5.86e-189 metQ - - P ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
NIIKMLNH_01289 6.5e-126 metI - - P ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2011 ABC-type metal ion transport system, permease component
NIIKMLNH_01290 2.15e-236 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NIIKMLNH_01291 1.53e-74 yusD - - S - - - SCP-2 sterol transfer family
NIIKMLNH_01292 6.7e-72 yusE - - CO - - - Thioredoxin
NIIKMLNH_01293 7.62e-97 yusF - - L ko:K07476 - ko00000 COG1658 Small primase-like proteins (Toprim domain)
NIIKMLNH_01294 7.34e-54 yusG - - S - - - Protein of unknown function (DUF2553)
NIIKMLNH_01295 5.91e-85 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
NIIKMLNH_01296 1.01e-83 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
NIIKMLNH_01297 0.0 fadE 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
NIIKMLNH_01298 1.34e-278 fadA 2.3.1.16 - I ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the thiolase family
NIIKMLNH_01299 0.0 fadN 1.1.1.35 - I ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 ko00000,ko00001,ko00002,ko01000 3-hydroxyacyl-CoA dehydrogenase
NIIKMLNH_01300 1.11e-13 - - - S - - - YuzL-like protein
NIIKMLNH_01301 1.21e-211 fadM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
NIIKMLNH_01302 2.23e-54 - - - - - - - -
NIIKMLNH_01303 8.66e-70 yusN - - M - - - Coat F domain
NIIKMLNH_01304 6.35e-98 yusO - - K - - - Iron dependent repressor, N-terminal DNA binding domain
NIIKMLNH_01305 0.0 yusP - - P - - - Major facilitator superfamily
NIIKMLNH_01306 4.86e-84 yusQ - - S - - - Tautomerase enzyme
NIIKMLNH_01307 7.05e-138 yusR 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
NIIKMLNH_01308 6.91e-203 gltR - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
NIIKMLNH_01309 3.01e-63 yusU - - S - - - Protein of unknown function (DUF2573)
NIIKMLNH_01310 8.74e-196 yusV 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
NIIKMLNH_01311 3.48e-88 - - - S - - - YusW-like protein
NIIKMLNH_01312 0.0 pepF2 - - E - - - COG1164 Oligoendopeptidase F
NIIKMLNH_01313 4.49e-196 yusZ - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
NIIKMLNH_01314 2.15e-104 fri - - P ko:K04047 - ko00000,ko03036 Ferritin-like domain
NIIKMLNH_01315 1.12e-304 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NIIKMLNH_01316 2.23e-164 cssR - - T ko:K07770 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NIIKMLNH_01317 2.77e-316 cssS 2.7.13.3 - T ko:K07650 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NIIKMLNH_01318 3.06e-204 yuxN - - K - - - Transcriptional regulator
NIIKMLNH_01319 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NIIKMLNH_01320 4.48e-34 - - - S - - - Protein of unknown function (DUF3970)
NIIKMLNH_01321 0.0 gerAA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
NIIKMLNH_01322 3.94e-251 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
NIIKMLNH_01323 3.05e-243 gerAC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination B3/ GerAC like, C-terminal
NIIKMLNH_01324 4.46e-139 vraR - - KT ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NIIKMLNH_01325 2.35e-245 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NIIKMLNH_01326 7.65e-164 - - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
NIIKMLNH_01327 1.41e-172 liaG - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
NIIKMLNH_01328 4.05e-142 liaH - - KT ko:K03969,ko:K11620 ko02020,map02020 ko00000,ko00001,ko00002 COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
NIIKMLNH_01329 1.51e-82 liaI - - S ko:K11619 ko02020,map02020 ko00000,ko00001,ko00002 membrane
NIIKMLNH_01330 6.23e-286 yvqJ - - EGP - - - COG0477 Permeases of the major facilitator superfamily
NIIKMLNH_01331 1.2e-129 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Adenosyltransferase
NIIKMLNH_01332 3.14e-310 yvrA 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
NIIKMLNH_01333 1.1e-235 btuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NIIKMLNH_01334 2.98e-218 btuF - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
NIIKMLNH_01335 2.12e-181 yvrD - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
NIIKMLNH_01336 1.32e-219 yvrE - - G ko:K14274 ko00040,map00040 ko00000,ko00001,ko01000 SMP-30/Gluconolaconase/LRE-like region
NIIKMLNH_01337 0.0 yvrG - - T - - - Histidine kinase
NIIKMLNH_01338 1.1e-170 yvrH - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NIIKMLNH_01339 6.16e-33 - - - - - - - -
NIIKMLNH_01340 7.02e-128 yvrI - - K ko:K03093 - ko00000,ko03021 RNA polymerase
NIIKMLNH_01341 3.46e-26 - - - S - - - YvrJ protein family
NIIKMLNH_01342 9.23e-292 oxdC 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
NIIKMLNH_01343 1.16e-84 yvrL - - S - - - Regulatory protein YrvL
NIIKMLNH_01344 2.21e-272 yvrN - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
NIIKMLNH_01345 3.82e-158 yvrO - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NIIKMLNH_01346 3.61e-231 - - - M ko:K02005 - ko00000 Efflux transporter rnd family, mfp subunit
NIIKMLNH_01347 2.92e-191 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
NIIKMLNH_01348 4.78e-226 fhuG - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NIIKMLNH_01349 2e-235 fhuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NIIKMLNH_01350 4.45e-225 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NIIKMLNH_01352 0.0 yvsH - - E ko:K03294,ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
NIIKMLNH_01353 9.37e-23 - - - S ko:K06427 - ko00000 Small spore protein J (Spore_SspJ)
NIIKMLNH_01354 2.38e-109 yvsG - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
NIIKMLNH_01355 0.0 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
NIIKMLNH_01356 6.98e-212 yvgK - - P ko:K07219 - ko00000 COG1910 Periplasmic molybdate-binding protein domain
NIIKMLNH_01357 1.22e-174 modA - - P ko:K02020 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0725 ABC-type molybdate transport system, periplasmic component
NIIKMLNH_01358 2.89e-152 modB - - P ko:K02018 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4149 ABC-type molybdate transport system, permease component
NIIKMLNH_01359 6.19e-201 yvgN - - S - - - reductase
NIIKMLNH_01360 7.97e-113 yvgO - - - - - - -
NIIKMLNH_01361 0.0 yvgP - - P ko:K03316 - ko00000 COG0025 NhaP-type Na H and K H antiporters
NIIKMLNH_01362 0.0 cysI 1.8.1.2, 1.8.7.1 - P ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
NIIKMLNH_01363 0.0 cysJ 1.8.1.2 - P ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NIIKMLNH_01364 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
NIIKMLNH_01366 2.34e-139 yvgT - - S - - - membrane
NIIKMLNH_01367 1.99e-95 bdbC - - O ko:K03611 - ko00000,ko03110 Required for disulfide bond formation in some proteins
NIIKMLNH_01368 3.45e-137 bdbD - - O - - - Thioredoxin
NIIKMLNH_01369 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
NIIKMLNH_01370 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
NIIKMLNH_01371 3.02e-40 copZ - - P ko:K07213 ko04978,map04978 ko00000,ko00001 Copper resistance protein CopZ
NIIKMLNH_01372 6.89e-65 csoR - - S ko:K21600 - ko00000,ko03000 transcriptional
NIIKMLNH_01373 3.3e-246 yvaA 1.1.1.371 - S ko:K16044 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
NIIKMLNH_01374 2.08e-153 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NIIKMLNH_01375 0.0 - - - S - - - Fusaric acid resistance protein-like
NIIKMLNH_01376 2.02e-97 yvaD - - S - - - Family of unknown function (DUF5360)
NIIKMLNH_01377 5.85e-70 yvaE - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
NIIKMLNH_01378 1.66e-126 - - - K - - - Bacterial regulatory proteins, tetR family
NIIKMLNH_01379 1.13e-181 yvaG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
NIIKMLNH_01381 2.4e-107 smpB - - O ko:K03664 - ko00000 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NIIKMLNH_01382 0.0 rnr - - K ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NIIKMLNH_01383 3.43e-183 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Carboxylesterase
NIIKMLNH_01384 1.87e-35 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
NIIKMLNH_01385 3.69e-181 yvaM 1.11.1.10 - S ko:K00433 - ko00000,ko01000 Serine aminopeptidase, S33
NIIKMLNH_01386 3.44e-48 yvzC - - K - - - transcriptional
NIIKMLNH_01387 4.77e-91 yvaO - - K ko:K22299 - ko00000,ko03000 transcriptional
NIIKMLNH_01388 7.76e-89 yvaO - - K ko:K22299 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
NIIKMLNH_01389 3.85e-72 yvaP - - K - - - transcriptional
NIIKMLNH_01390 0.0 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
NIIKMLNH_01391 2.26e-144 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
NIIKMLNH_01392 2.27e-218 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NIIKMLNH_01393 1.55e-142 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
NIIKMLNH_01394 7.34e-271 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
NIIKMLNH_01395 6.63e-122 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
NIIKMLNH_01396 5.59e-136 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
NIIKMLNH_01397 1.23e-221 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NIIKMLNH_01398 1.61e-144 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
NIIKMLNH_01399 1.26e-266 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
NIIKMLNH_01400 8.29e-129 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
NIIKMLNH_01401 3.94e-135 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
NIIKMLNH_01402 2.96e-145 yvbH - - S - - - YvbH-like oligomerisation region
NIIKMLNH_01403 2.28e-156 yvbI - - M - - - Membrane
NIIKMLNH_01404 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
NIIKMLNH_01405 9.77e-106 yvbK - - K - - - acetyltransferase
NIIKMLNH_01406 1.38e-309 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NIIKMLNH_01407 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and
NIIKMLNH_01408 2.12e-176 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NIIKMLNH_01409 1.97e-277 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
NIIKMLNH_01410 5.72e-238 gapA 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NIIKMLNH_01411 5.69e-236 cggR - - K ko:K05311 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
NIIKMLNH_01412 0.0 araE - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NIIKMLNH_01413 4.32e-258 araR - - K ko:K02103 - ko00000,ko03000 transcriptional
NIIKMLNH_01414 8.53e-245 yvbT - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NIIKMLNH_01415 3.31e-204 yvbU - - K - - - Transcriptional regulator
NIIKMLNH_01416 1.6e-197 yvbV - - EG - - - EamA-like transporter family
NIIKMLNH_01417 7.07e-307 yvbW - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
NIIKMLNH_01418 1.22e-248 - - - S - - - Glycosyl hydrolase
NIIKMLNH_01419 1.14e-169 lutC - - S ko:K00782 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
NIIKMLNH_01420 0.0 lutB - - C ko:K18929 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
NIIKMLNH_01421 1.06e-173 lutA - - C ko:K18928 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
NIIKMLNH_01422 3.88e-57 - - - S - - - Protein of unknown function (DUF2812)
NIIKMLNH_01423 4.23e-42 - - - K - - - Transcriptional regulator PadR-like family
NIIKMLNH_01424 7.23e-135 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NIIKMLNH_01425 1.54e-251 yvfT 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NIIKMLNH_01426 5.85e-170 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
NIIKMLNH_01427 2.9e-200 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
NIIKMLNH_01429 2.08e-200 rsbQ - - S ko:K19707 - ko00000,ko03021 Alpha/beta hydrolase family
NIIKMLNH_01430 1.52e-265 - 3.1.3.3 - T ko:K07315 - ko00000,ko01000,ko03021 response regulator
NIIKMLNH_01431 0.0 ganB 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
NIIKMLNH_01432 0.0 lacA 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 beta-galactosidase
NIIKMLNH_01433 3.82e-194 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
NIIKMLNH_01434 1.3e-301 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
NIIKMLNH_01435 4.62e-292 cycB - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
NIIKMLNH_01436 2e-236 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
NIIKMLNH_01437 6.85e-146 yvfI - - K ko:K05799 - ko00000,ko03000 COG2186 Transcriptional regulators
NIIKMLNH_01438 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
NIIKMLNH_01439 7.87e-303 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
NIIKMLNH_01440 5.69e-44 yvfG - - S - - - YvfG protein
NIIKMLNH_01441 4.69e-235 epsO - - GM ko:K19431 - ko00000,ko01000 Exopolysaccharide biosynthesis protein
NIIKMLNH_01442 7.46e-279 epsN - - E ko:K19430 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
NIIKMLNH_01443 3.33e-76 epsM - - GM ko:K19429 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
NIIKMLNH_01444 9.14e-139 epsL - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 COG2148 Sugar transferases involved in lipopolysaccharide synthesis
NIIKMLNH_01445 0.0 epsK - - S ko:K19418 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NIIKMLNH_01446 3.5e-248 epsJ - GT2 S ko:K19427 - ko00000,ko01000 COG0463 Glycosyltransferases involved in cell wall biogenesis
NIIKMLNH_01447 1.57e-258 epsI - - GM ko:K19426 - ko00000,ko01000 pyruvyl transferase
NIIKMLNH_01448 1.22e-248 epsH - GT2 S ko:K19425 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
NIIKMLNH_01449 8.82e-265 epsG - - S ko:K19419 - ko00000,ko02000 EpsG family
NIIKMLNH_01450 4.48e-278 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
NIIKMLNH_01451 1.25e-201 epsE - GT2 M ko:K19423 - ko00000,ko01000,ko01003 COG0463 Glycosyltransferases involved in cell wall biogenesis
NIIKMLNH_01452 7.45e-280 epsD - GT4 M ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like
NIIKMLNH_01453 0.0 capD - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
NIIKMLNH_01454 3.77e-148 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
NIIKMLNH_01455 1.61e-157 epsA - - M ko:K19420 - ko00000 biosynthesis protein
NIIKMLNH_01456 3.57e-98 - - - K ko:K19417 - ko00000,ko03000 transcriptional
NIIKMLNH_01457 0.0 pnbA - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
NIIKMLNH_01459 5.4e-120 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
NIIKMLNH_01460 7.42e-95 - - - S - - - Protein of unknown function (DUF3237)
NIIKMLNH_01461 1.19e-160 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
NIIKMLNH_01462 0.0 pbpE - - V - - - Beta-lactamase
NIIKMLNH_01463 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 levansucrase activity
NIIKMLNH_01464 0.0 sacC3 3.2.1.65 GH32 G ko:K01212 ko00500,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
NIIKMLNH_01465 0.0 ybeC - - E - - - amino acid
NIIKMLNH_01466 2.75e-136 yvdT_1 - - K - - - Transcriptional regulator
NIIKMLNH_01467 3.65e-67 yvdS - - P ko:K18924 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
NIIKMLNH_01468 2.08e-66 yvdR - - P ko:K11741 - ko00000,ko02000 Small Multidrug Resistance protein
NIIKMLNH_01469 2.63e-120 yvdQ - - S - - - Protein of unknown function (DUF3231)
NIIKMLNH_01471 8.17e-135 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NIIKMLNH_01472 3.09e-146 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
NIIKMLNH_01473 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
NIIKMLNH_01474 0.0 yvdK 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycoside hydrolase, family 65
NIIKMLNH_01475 8.09e-202 malA - - S - - - Protein of unknown function (DUF1189)
NIIKMLNH_01476 3.96e-189 malD - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
NIIKMLNH_01477 1.01e-309 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
NIIKMLNH_01478 6.95e-301 mdxE - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
NIIKMLNH_01479 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, N-terminal ig-like domain
NIIKMLNH_01480 1.54e-221 yvdE - - K - - - Transcriptional regulator
NIIKMLNH_01481 2.66e-137 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
NIIKMLNH_01482 7.84e-71 yvdC - - S - - - MazG nucleotide pyrophosphohydrolase domain
NIIKMLNH_01483 0.0 yvdB - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
NIIKMLNH_01484 1.03e-134 yvdA 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
NIIKMLNH_01485 2.7e-233 yvcT 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NIIKMLNH_01486 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
NIIKMLNH_01487 4.46e-181 yxdL_2 - - V ko:K02003,ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NIIKMLNH_01488 3.24e-250 yvcQ - - T - - - His Kinase A (phosphoacceptor) domain
NIIKMLNH_01489 3.84e-171 yvcP - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NIIKMLNH_01490 1.32e-43 - - - - - - - -
NIIKMLNH_01491 1.33e-181 yvcN 2.3.1.118 - Q ko:K00675 - ko00000,ko01000 Belongs to the arylamine N-acetyltransferase family
NIIKMLNH_01492 3.92e-50 crh - - G ko:K11184 - ko00000 Phosphocarrier protein Chr
NIIKMLNH_01493 1.04e-219 whiA - - K ko:K09762 - ko00000 May be required for sporulation
NIIKMLNH_01494 6.72e-227 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
NIIKMLNH_01495 2.09e-213 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
NIIKMLNH_01496 2.39e-117 yvcI 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
NIIKMLNH_01497 1.18e-225 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NIIKMLNH_01498 1.89e-185 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 protein conserved in bacteria
NIIKMLNH_01499 0.0 yvcD - - S - - - COG0457 FOG TPR repeat
NIIKMLNH_01500 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
NIIKMLNH_01502 0.0 - - - - - - - -
NIIKMLNH_01503 7.43e-171 - - - - - - - -
NIIKMLNH_01504 4.86e-142 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the PRA-CH family
NIIKMLNH_01505 5.63e-176 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NIIKMLNH_01506 1.27e-164 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NIIKMLNH_01507 5.24e-143 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NIIKMLNH_01508 1.17e-137 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
NIIKMLNH_01509 3e-291 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NIIKMLNH_01510 1.06e-147 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
NIIKMLNH_01511 2.42e-281 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NIIKMLNH_01512 1.76e-178 yvpB - - NU - - - protein conserved in bacteria
NIIKMLNH_01513 3.15e-153 - 4.2.2.10, 4.2.2.2 - G ko:K19551 ko00040,map00040 ko00000,ko00001,ko01000 Pectate lyase
NIIKMLNH_01514 5.94e-118 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
NIIKMLNH_01515 3.05e-153 ppaX 3.6.1.1 - S ko:K06019 ko00190,map00190 ko00000,ko00001,ko01000 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
NIIKMLNH_01516 2.06e-208 yvoD - - P - - - COG0370 Fe2 transport system protein B
NIIKMLNH_01517 2.61e-194 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NIIKMLNH_01518 3.62e-217 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NIIKMLNH_01519 9.81e-279 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
NIIKMLNH_01520 1.43e-164 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NIIKMLNH_01521 3.02e-171 yvoA - - K ko:K03710 - ko00000,ko03000 transcriptional
NIIKMLNH_01522 0.0 yvnB - - Q - - - Calcineurin-like phosphoesterase
NIIKMLNH_01523 4.06e-94 yvnA - - K - - - helix_turn_helix multiple antibiotic resistance protein
NIIKMLNH_01524 2.45e-288 cypX 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
NIIKMLNH_01525 8.35e-176 yvmC 2.3.2.22 - S ko:K17485 - ko00000,ko01000 Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
NIIKMLNH_01526 6.2e-114 yvmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
NIIKMLNH_01527 4.96e-271 yvmA - - EGP - - - Major Facilitator Superfamily
NIIKMLNH_01528 3.8e-66 yvlD - - S ko:K08972 - ko00000 Membrane
NIIKMLNH_01529 1.5e-36 yvlC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
NIIKMLNH_01530 9.59e-220 yvlB - - S - - - Putative adhesin
NIIKMLNH_01531 9.45e-64 yvlA - - - - - - -
NIIKMLNH_01532 2.25e-45 yvkN - - - - - - -
NIIKMLNH_01533 3.03e-147 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NIIKMLNH_01534 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NIIKMLNH_01535 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NIIKMLNH_01536 2.54e-42 csbA - - S - - - protein conserved in bacteria
NIIKMLNH_01537 0.0 yvkC 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Phosphotransferase
NIIKMLNH_01538 1.43e-131 yvkB - - K - - - Transcriptional regulator
NIIKMLNH_01539 3.03e-295 yvkA - - P - - - -transporter
NIIKMLNH_01540 3.17e-280 minJ - - O - - - COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NIIKMLNH_01541 1.38e-73 swrA - - S - - - Swarming motility protein
NIIKMLNH_01542 0.0 ctpB 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
NIIKMLNH_01543 5.45e-199 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
NIIKMLNH_01544 1.5e-159 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
NIIKMLNH_01545 2.19e-71 cccB - - C ko:K12263,ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
NIIKMLNH_01546 6.5e-185 yvjA - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
NIIKMLNH_01547 2e-232 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NIIKMLNH_01548 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NIIKMLNH_01549 1.73e-132 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NIIKMLNH_01550 2.46e-67 - - - - - - - -
NIIKMLNH_01551 8.69e-09 fliT - - S ko:K02423 ko02040,map02040 ko00000,ko00001,ko02035 bacterial-type flagellum organization
NIIKMLNH_01552 5.15e-91 fliS - - N ko:K02422 ko02040,map02040 ko00000,ko00001,ko02035 flagellar protein FliS
NIIKMLNH_01553 0.0 fliD - - N ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
NIIKMLNH_01554 9.02e-76 flaG - - N ko:K06603 - ko00000,ko02035 flagellar protein FlaG
NIIKMLNH_01555 1.44e-104 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NIIKMLNH_01556 2.58e-41 csrA - - T ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 ko00000,ko00001,ko03019 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
NIIKMLNH_01557 1.23e-96 fliW - - S ko:K13626 - ko00000,ko02035 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
NIIKMLNH_01558 1.7e-92 yviE - - - - - - -
NIIKMLNH_01559 3.8e-197 flgL - - N ko:K02397 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the bacterial flagellin family
NIIKMLNH_01560 0.0 flgK - - N ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 flagellar hook-associated protein
NIIKMLNH_01561 7.06e-102 yvyG - - NOU - - - FlgN protein
NIIKMLNH_01562 8.72e-53 flgM - - KNU ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 ko00000,ko00001,ko02035 Negative regulator of flagellin synthesis
NIIKMLNH_01563 1.83e-96 yvyF - - S - - - flagellar protein
NIIKMLNH_01564 6.48e-162 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Phosphoribosyl transferase domain
NIIKMLNH_01565 5.13e-61 comFB - - S ko:K02241 - ko00000,ko00002,ko02044 Late competence development protein ComFB
NIIKMLNH_01566 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
NIIKMLNH_01567 4.16e-197 degV - - S - - - protein conserved in bacteria
NIIKMLNH_01568 7.16e-163 degU - - KT ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NIIKMLNH_01569 2.94e-247 degS 2.7.13.3 - T ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
NIIKMLNH_01570 2.41e-155 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 Domain of unknown function (DUF1949)
NIIKMLNH_01571 3.12e-222 yvhJ - - K - - - Transcriptional regulator
NIIKMLNH_01572 2.1e-231 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
NIIKMLNH_01573 4.13e-297 tuaH - - M ko:K16699 - ko00000,ko01000,ko01003 Teichuronic acid biosynthesis glycosyltransferase tuaH
NIIKMLNH_01574 6.92e-186 tuaG - GT2 M ko:K16698 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
NIIKMLNH_01575 1.42e-147 tuaF - - M ko:K16706 - ko00000 protein involved in exopolysaccharide biosynthesis
NIIKMLNH_01576 0.0 tuaE - - M ko:K16705 - ko00000 Teichuronic acid biosynthesis protein
NIIKMLNH_01577 0.0 tuaD 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NIIKMLNH_01578 1.19e-280 tuaC - GT4 GM ko:K16697 - ko00000,ko01000,ko01003 Teichuronic acid
NIIKMLNH_01579 1.03e-315 tuaB - - S ko:K03328,ko:K16694,ko:K16695 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NIIKMLNH_01580 1.49e-143 tuaA - - M - - - COG2148 Sugar transferases involved in lipopolysaccharide synthesis
NIIKMLNH_01581 5.9e-117 - - - M - - - Glycosyltransferase like family 2
NIIKMLNH_01582 5.81e-261 lytC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
NIIKMLNH_01583 0.0 lytB - - D - - - Stage II sporulation protein
NIIKMLNH_01584 4.58e-16 - - - - - - - -
NIIKMLNH_01585 1.16e-211 lytR - - K - - - May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
NIIKMLNH_01586 2.03e-272 mnaA 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NIIKMLNH_01587 2.09e-103 - - - M - - - Glycosyltransferase like family 2
NIIKMLNH_01588 4.85e-118 - - - M - - - Glycosyl transferases group 1
NIIKMLNH_01591 1.25e-204 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
NIIKMLNH_01592 0.0 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
NIIKMLNH_01593 1.08e-164 tagG - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
NIIKMLNH_01594 5.55e-66 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase
NIIKMLNH_01595 1.02e-155 - - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
NIIKMLNH_01596 6.23e-205 - 2.7.8.14, 2.7.8.47 - M ko:K18704 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NIIKMLNH_01597 7.2e-113 tagA 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
NIIKMLNH_01598 3.59e-91 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NIIKMLNH_01599 2.07e-134 tarI 2.7.7.40, 2.7.7.60 - I ko:K00991,ko:K21030 ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
NIIKMLNH_01600 5.68e-186 tarJ 1.1.1.137, 1.1.1.405 - E ko:K05352,ko:K21680 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
NIIKMLNH_01601 2.47e-109 tarK 2.7.8.14, 2.7.8.46, 2.7.8.47 - M ko:K18704,ko:K21592 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NIIKMLNH_01602 1.42e-235 tarL 2.7.8.14, 2.7.8.47 - M ko:K18704 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NIIKMLNH_01603 0.0 lytD 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NIIKMLNH_01604 1.84e-238 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
NIIKMLNH_01605 1.55e-310 gerBA - - EG ko:K06291,ko:K06310 - ko00000 Spore germination protein
NIIKMLNH_01606 2.06e-239 gerBB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
NIIKMLNH_01607 8.28e-253 gerBC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination protein
NIIKMLNH_01608 9.1e-315 ywtG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NIIKMLNH_01609 1.42e-220 ywtF_2 - - K - - - Transcriptional regulator
NIIKMLNH_01610 2.32e-201 ywtE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
NIIKMLNH_01611 1.37e-304 pgdS - - M - - - COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
NIIKMLNH_01612 2.29e-29 ywtC - - - - - - -
NIIKMLNH_01613 1.1e-276 capA - - M ko:K07282 - ko00000 enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
NIIKMLNH_01614 8.44e-91 capC - - S ko:K22116 - ko00000 biosynthesis protein
NIIKMLNH_01615 1.46e-283 capB - - M ko:K01932 - ko00000,ko01000 COG0769 UDP-N-acetylmuramyl tripeptide synthase
NIIKMLNH_01616 2.68e-227 rbsR - - K ko:K02529 - ko00000,ko03000 transcriptional
NIIKMLNH_01617 5.92e-203 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NIIKMLNH_01618 4.61e-84 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
NIIKMLNH_01619 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
NIIKMLNH_01620 3.35e-203 rbsC - - G ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
NIIKMLNH_01621 3.68e-203 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 COG1879 ABC-type sugar transport system, periplasmic component
NIIKMLNH_01622 1.55e-116 batE - - T - - - Sh3 type 3 domain protein
NIIKMLNH_01623 2.17e-62 ywsA - - S - - - Protein of unknown function (DUF3892)
NIIKMLNH_01624 3.57e-125 ywrO - - S - - - NADPH-quinone reductase (modulator of drug activity B)
NIIKMLNH_01625 6.15e-186 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
NIIKMLNH_01626 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
NIIKMLNH_01627 3.36e-218 alsR - - K - - - LysR substrate binding domain
NIIKMLNH_01628 1.32e-278 ywrK - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NIIKMLNH_01629 3.56e-161 ywrJ - - - - - - -
NIIKMLNH_01630 1.99e-171 cotB - - - ko:K06325 - ko00000 -
NIIKMLNH_01631 2.08e-265 cotH - - M ko:K06330 - ko00000 Spore Coat
NIIKMLNH_01632 3.41e-17 - - - - - - - -
NIIKMLNH_01633 6.18e-143 ywrF - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NIIKMLNH_01634 1.13e-70 - - - S - - - Domain of unknown function (DUF4181)
NIIKMLNH_01635 0.0 ywrD 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
NIIKMLNH_01636 2.79e-107 ywrC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
NIIKMLNH_01637 4.53e-132 ywrB - - P ko:K07240 - ko00000,ko02000 Chromate transporter
NIIKMLNH_01638 6.07e-114 ywrA - - P ko:K07240 - ko00000,ko02000 COG2059 Chromate transport protein ChrA
NIIKMLNH_01640 1.24e-149 nfi 3.1.21.7 - L ko:K05982 - ko00000,ko01000,ko03400 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
NIIKMLNH_01642 1.01e-302 ywqJ - - S - - - Pre-toxin TG
NIIKMLNH_01643 1.04e-51 ywqI - - S - - - Family of unknown function (DUF5344)
NIIKMLNH_01645 3.59e-197 ywqG - - S - - - Domain of unknown function (DUF1963)
NIIKMLNH_01646 7.72e-312 ywqF 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NIIKMLNH_01647 2.05e-179 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 COG4464 Capsular polysaccharide biosynthesis protein
NIIKMLNH_01648 8.57e-157 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
NIIKMLNH_01649 5.33e-163 ywqC - - M ko:K19420 - ko00000 biosynthesis protein
NIIKMLNH_01650 3.6e-25 - - - - - - - -
NIIKMLNH_01651 0.0 ywqB - - S - - - SWIM zinc finger
NIIKMLNH_01652 0.0 ywqA - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
NIIKMLNH_01653 5.07e-200 ywpJ 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
NIIKMLNH_01654 4.82e-180 glcR - - K ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
NIIKMLNH_01655 8.53e-76 ssbB - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
NIIKMLNH_01656 5.26e-88 ywpG - - - - - - -
NIIKMLNH_01657 8.81e-89 ywpF - - S - - - YwpF-like protein
NIIKMLNH_01658 5.85e-107 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
NIIKMLNH_01659 0.0 - - - M - - - cell wall anchor domain
NIIKMLNH_01660 1.68e-221 M1-574 - - T - - - Transcriptional regulatory protein, C terminal
NIIKMLNH_01661 0.0 ywpD - - T - - - Histidine kinase
NIIKMLNH_01662 1.32e-76 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NIIKMLNH_01663 6.89e-107 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NIIKMLNH_01664 8.66e-254 rapD - - S ko:K06362 - ko00000,ko01000 aspartate phosphatase
NIIKMLNH_01665 1.17e-181 flhP - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
NIIKMLNH_01666 1.77e-172 flhO - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
NIIKMLNH_01667 1.75e-231 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein
NIIKMLNH_01668 4.88e-59 spoIIID - - K ko:K06283 - ko00000,ko03000 Stage III sporulation protein D
NIIKMLNH_01669 8.45e-92 - - - K - - - COG1846 Transcriptional regulators
NIIKMLNH_01670 1.37e-269 ywoG - - EGP - - - COG0477 Permeases of the major facilitator superfamily
NIIKMLNH_01672 1.97e-310 ywoF - - P - - - Right handed beta helix region
NIIKMLNH_01673 0.0 - - - FH ko:K03457,ko:K10975 - ko00000,ko02000 COG1953 Cytosine uracil thiamine allantoin permeases
NIIKMLNH_01674 4.62e-308 ywoD - - EGP - - - Major facilitator superfamily
NIIKMLNH_01675 6.05e-133 yjgF - - Q - - - Isochorismatase family
NIIKMLNH_01676 5.04e-101 - - - - - - - -
NIIKMLNH_01677 1.6e-288 nrgA - - P ko:K03320 - ko00000,ko02000 Ammonium transporter
NIIKMLNH_01678 4.51e-77 nrgB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
NIIKMLNH_01679 1.21e-134 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 COG0671 Membrane-associated phospholipid phosphatase
NIIKMLNH_01680 1.98e-92 ywnJ - - S - - - VanZ like family
NIIKMLNH_01681 1.85e-161 spoIIQ - - M ko:K06386 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
NIIKMLNH_01682 6.31e-116 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 COG1247 Sortase and related acyltransferases
NIIKMLNH_01683 6.55e-22 ywnC - - S - - - Family of unknown function (DUF5362)
NIIKMLNH_01684 7.07e-92 ywnF - - S - - - Family of unknown function (DUF5392)
NIIKMLNH_01685 0.0 ywnE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NIIKMLNH_01686 4.65e-182 mta - - K ko:K21743 - ko00000,ko03000 transcriptional
NIIKMLNH_01687 8.72e-78 ywnC - - S - - - Family of unknown function (DUF5362)
NIIKMLNH_01688 1.51e-147 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
NIIKMLNH_01689 1.08e-83 ywnA - - K - - - Transcriptional regulator
NIIKMLNH_01690 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
NIIKMLNH_01691 1.12e-83 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
NIIKMLNH_01692 8.2e-68 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
NIIKMLNH_01693 2.73e-28 - - - E ko:K11963 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
NIIKMLNH_01694 1.11e-21 csbD - - K - - - CsbD-like
NIIKMLNH_01695 1.66e-109 ywmF - - S - - - Peptidase M50
NIIKMLNH_01696 3.1e-129 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
NIIKMLNH_01697 1.08e-245 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NIIKMLNH_01698 9.06e-187 fdhD - - C ko:K02379 - ko00000 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NIIKMLNH_01700 1.02e-155 ywmD - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
NIIKMLNH_01701 1.89e-157 ywmC - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
NIIKMLNH_01702 9.77e-234 spoIID - - D ko:K06381 - ko00000 Stage II sporulation protein D
NIIKMLNH_01703 4.96e-306 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NIIKMLNH_01704 2.3e-172 ywmB - - S - - - TATA-box binding
NIIKMLNH_01705 4.54e-45 ywzB - - S - - - membrane
NIIKMLNH_01706 7.16e-114 ywmA - - - - - - -
NIIKMLNH_01707 3.89e-72 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
NIIKMLNH_01708 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NIIKMLNH_01709 4.46e-195 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NIIKMLNH_01710 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NIIKMLNH_01711 3.23e-115 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NIIKMLNH_01712 2.62e-79 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NIIKMLNH_01713 3.01e-36 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NIIKMLNH_01714 6.06e-167 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
NIIKMLNH_01715 1.91e-81 atpI - - S ko:K02116 - ko00000,ko00194 ATP synthase
NIIKMLNH_01716 5.5e-148 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NIIKMLNH_01717 1.25e-302 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NIIKMLNH_01718 2.49e-123 ywlG - - S - - - Belongs to the UPF0340 family
NIIKMLNH_01719 2.35e-106 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase
NIIKMLNH_01720 1.58e-100 ywlE 3.1.3.48, 3.9.1.2 - T ko:K01104,ko:K20201 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NIIKMLNH_01721 1.86e-116 mntP - - P - - - Probably functions as a manganese efflux pump
NIIKMLNH_01722 1.22e-249 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NIIKMLNH_01723 1.79e-100 ywlB - - E - - - Belongs to the acetyltransferase family. ArgA subfamily
NIIKMLNH_01724 3.26e-152 spoIIR - - S ko:K06387 - ko00000 stage II sporulation protein R
NIIKMLNH_01725 9.69e-74 ywlA - - S - - - Uncharacterised protein family (UPF0715)
NIIKMLNH_01727 5.96e-205 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NIIKMLNH_01728 9.95e-245 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NIIKMLNH_01729 4.84e-89 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NIIKMLNH_01730 8.18e-115 racA - - K ko:K11686 - ko00000,ko03036 Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
NIIKMLNH_01731 3.24e-204 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
NIIKMLNH_01732 0.0 ykwA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
NIIKMLNH_01733 9.96e-135 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
NIIKMLNH_01734 7e-45 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
NIIKMLNH_01735 5.53e-303 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NIIKMLNH_01736 3.51e-225 glpX 3.1.3.11 - G ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 fructose-1,6-bisphosphatase
NIIKMLNH_01737 2.26e-303 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NIIKMLNH_01738 5.69e-147 tal 2.2.1.2 - G ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NIIKMLNH_01739 7.82e-204 fbaA 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Aldolase
NIIKMLNH_01740 1.07e-81 spo0F - - T ko:K02490 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG0784 FOG CheY-like receiver
NIIKMLNH_01741 6.41e-118 ywjG - - S - - - Domain of unknown function (DUF2529)
NIIKMLNH_01742 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NIIKMLNH_01743 1.03e-82 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NIIKMLNH_01744 2.98e-269 acdA - - I - - - acyl-CoA dehydrogenase
NIIKMLNH_01745 0.0 ywjF - - C - - - COG0247 Fe-S oxidoreductase
NIIKMLNH_01746 3.43e-262 clsB - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the phospholipase D family. Cardiolipin synthase subfamily
NIIKMLNH_01747 9.45e-234 uvsE - - L ko:K13281 - ko00000,ko01000 Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
NIIKMLNH_01748 1.32e-57 ywjC - - - - - - -
NIIKMLNH_01749 5.49e-124 ywjB - - H - - - RibD C-terminal domain
NIIKMLNH_01750 0.0 ywjA - - V ko:K06147 - ko00000,ko02000 ABC transporter
NIIKMLNH_01751 0.0 ywiE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NIIKMLNH_01752 1.02e-159 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase (gamma
NIIKMLNH_01753 6.53e-121 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase
NIIKMLNH_01754 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase, beta
NIIKMLNH_01755 0.0 narG 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NIIKMLNH_01756 8.67e-111 arfM - - T ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 cyclic nucleotide binding
NIIKMLNH_01757 1.84e-179 ywiC - - S - - - YwiC-like protein
NIIKMLNH_01758 3.27e-168 fnr - - K - - - helix_turn_helix, cAMP Regulatory protein
NIIKMLNH_01759 6.83e-274 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
NIIKMLNH_01760 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
NIIKMLNH_01761 4.64e-96 ywiB - - S - - - protein conserved in bacteria
NIIKMLNH_01762 3.71e-12 - - - S - - - Bacteriocin subtilosin A
NIIKMLNH_01763 0.0 - - - C ko:K22227 - ko00000 Fe-S oxidoreductases
NIIKMLNH_01765 1.5e-169 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
NIIKMLNH_01766 1.33e-294 mgtA 3.6.3.2 - P ko:K01531,ko:K16905 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPase, P-type transporting, HAD superfamily, subfamily IC
NIIKMLNH_01767 8.09e-275 - 2.7.1.26, 2.7.7.2 - L ko:K07263,ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01002 Peptidase, M16
NIIKMLNH_01768 2.68e-314 - - - L - - - Peptidase, M16
NIIKMLNH_01770 1.15e-313 ywhL - - CO - - - amine dehydrogenase activity
NIIKMLNH_01771 5.47e-274 ywhK - - CO - - - amine dehydrogenase activity
NIIKMLNH_01772 9.28e-99 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
NIIKMLNH_01775 1.3e-10 - - - - - - - -
NIIKMLNH_01778 1.4e-74 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
NIIKMLNH_01780 2.1e-215 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
NIIKMLNH_01781 1.93e-204 speE 2.5.1.16 - E ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NIIKMLNH_01782 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M ko:K21464 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
NIIKMLNH_01783 1.92e-123 ywhD - - S - - - YwhD family
NIIKMLNH_01784 3.29e-154 ywhC - - S - - - Peptidase family M50
NIIKMLNH_01785 1.43e-35 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 4-oxalocrotonate tautomerase
NIIKMLNH_01786 1.45e-93 ywhA - - K - - - Transcriptional regulator
NIIKMLNH_01787 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NIIKMLNH_01789 1.85e-301 mmr - - U ko:K08166 - ko00000,ko02000 Major Facilitator Superfamily
NIIKMLNH_01790 3.15e-103 yffB - - K - - - Transcriptional regulator
NIIKMLNH_01791 1.47e-115 ywgA - - - ko:K09388 - ko00000 -
NIIKMLNH_01792 0.0 ywfO - - S ko:K06885 - ko00000 COG1078 HD superfamily phosphohydrolases
NIIKMLNH_01793 8.55e-49 ywzC - - S - - - Belongs to the UPF0741 family
NIIKMLNH_01794 5.39e-145 rsfA_1 - - - ko:K06314 - ko00000,ko03000 -
NIIKMLNH_01795 4.32e-202 ywfM - - EG ko:K03298 - ko00000,ko02000 EamA-like transporter family
NIIKMLNH_01796 1.77e-198 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
NIIKMLNH_01797 3.73e-209 cysL - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
NIIKMLNH_01798 1.67e-224 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 In Salmonella this enzyme is required for ethanolamine catabolism
NIIKMLNH_01799 3.43e-187 ywfI - - C ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko01000 May function as heme-dependent peroxidase
NIIKMLNH_01800 3.93e-175 ywfH - - IQ ko:K19550 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Enoyl-(Acyl carrier protein) reductase
NIIKMLNH_01801 2.47e-294 ywfG - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
NIIKMLNH_01802 7.22e-264 bacE - - EGP ko:K19552 - ko00000,ko02000 Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
NIIKMLNH_01803 0.0 bacD 6.3.2.49 - F ko:K13037 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
NIIKMLNH_01804 3.83e-179 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NIIKMLNH_01805 1.24e-175 bacB 5.3.3.19 - S ko:K19547 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
NIIKMLNH_01806 5.11e-146 bacA 4.1.1.100 - E ko:K19546 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
NIIKMLNH_01807 8.95e-274 ywfA - - EGP - - - -transporter
NIIKMLNH_01808 2.65e-316 rocC - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
NIIKMLNH_01809 0.0 rocB - - E - - - arginine degradation protein
NIIKMLNH_01810 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
NIIKMLNH_01811 5.19e-311 rocG 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
NIIKMLNH_01812 6.13e-100 - - - - - - - -
NIIKMLNH_01813 3.73e-113 spsL 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Spore Coat
NIIKMLNH_01814 1.64e-204 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NIIKMLNH_01815 5.26e-233 spsJ 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NIIKMLNH_01816 6.13e-177 spsI 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NIIKMLNH_01817 6.69e-239 spsG - - M - - - Spore Coat
NIIKMLNH_01818 5.2e-166 spsF - - M ko:K07257 - ko00000 Spore Coat
NIIKMLNH_01819 6.8e-272 pseI 2.5.1.56, 2.5.1.97 - M ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 acid synthase
NIIKMLNH_01820 1.04e-210 spsD 2.3.1.210 - K ko:K16704 - ko00000,ko01000 Spore Coat
NIIKMLNH_01821 4.54e-285 spsC 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
NIIKMLNH_01822 0.0 spsB - - M - - - Capsule polysaccharide biosynthesis protein
NIIKMLNH_01823 6.64e-186 spsA - - M - - - Spore Coat
NIIKMLNH_01824 3.62e-112 gerQ - - S ko:K06305 - ko00000 Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
NIIKMLNH_01825 1.59e-78 ywdK - - S - - - small membrane protein
NIIKMLNH_01826 1.86e-303 ywdJ - - F - - - Xanthine uracil
NIIKMLNH_01827 2.18e-63 ywdI - - S - - - Family of unknown function (DUF5327)
NIIKMLNH_01828 0.0 ywdH 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
NIIKMLNH_01829 9.47e-166 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NIIKMLNH_01830 4.68e-192 ywdF - - S - - - Glycosyltransferase like family 2
NIIKMLNH_01831 2.21e-187 pdxK 2.7.1.35, 2.7.1.49, 2.7.4.7 - H ko:K00868,ko:K00941 ko00730,ko00750,ko01100,map00730,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
NIIKMLNH_01832 1.07e-39 ywdA - - - - - - -
NIIKMLNH_01833 0.0 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
NIIKMLNH_01834 0.0 sacP 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NIIKMLNH_01835 4.82e-179 - - - P ko:K02598 - ko00000,ko02000 Formate/nitrite transporter
NIIKMLNH_01836 2.6e-193 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
NIIKMLNH_01838 0.0 prtS 3.4.21.110, 3.4.21.96 - O ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
NIIKMLNH_01839 5.71e-237 ywcH - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NIIKMLNH_01840 9.4e-178 nfrA1 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Oxidoreductase
NIIKMLNH_01841 9.57e-241 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
NIIKMLNH_01842 6.61e-52 ywcE - - S - - - Required for proper spore morphogenesis. Important for spore germination
NIIKMLNH_01843 1.12e-83 qoxD 1.10.3.12 - C ko:K02829 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
NIIKMLNH_01844 1.2e-144 qoxC 1.10.3.12 - C ko:K02828 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
NIIKMLNH_01845 0.0 qoxB 1.10.3.12 - C ko:K02827 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NIIKMLNH_01846 4.96e-213 qoxA 1.10.3.12 - C ko:K02826 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
NIIKMLNH_01847 5.11e-49 ydaS - - S - - - membrane
NIIKMLNH_01848 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
NIIKMLNH_01849 4.38e-288 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NIIKMLNH_01850 4.72e-77 gtcA - - S - - - GtrA-like protein
NIIKMLNH_01851 3.42e-158 ywcC - - K - - - transcriptional regulator
NIIKMLNH_01853 2.13e-64 ywcB - - S - - - Protein of unknown function, DUF485
NIIKMLNH_01854 0.0 ywcA - - S ko:K14393 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NIIKMLNH_01855 1.32e-143 ywbO - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
NIIKMLNH_01856 1.47e-306 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Dyp-type peroxidase family protein
NIIKMLNH_01857 1.7e-246 ycdO - - P ko:K07224 - ko00000,ko02000 periplasmic lipoprotein involved in iron transport
NIIKMLNH_01858 0.0 - - - P ko:K07243 - ko00000,ko02000 COG0672 High-affinity Fe2 Pb2 permease
NIIKMLNH_01859 1.43e-145 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
NIIKMLNH_01860 3.25e-185 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NIIKMLNH_01861 2.7e-203 ywbI - - K - - - Transcriptional regulator
NIIKMLNH_01862 1.1e-76 ywbH - - S ko:K06518 - ko00000,ko02000 Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
NIIKMLNH_01863 1.21e-143 ywbG - - M - - - effector of murein hydrolase
NIIKMLNH_01864 1.01e-275 ywbF - - EGP ko:K05820 - ko00000,ko02000 Nucleoside H+ symporter
NIIKMLNH_01865 3.13e-38 ywbE - - S - - - Uncharacterized conserved protein (DUF2196)
NIIKMLNH_01866 1.1e-277 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
NIIKMLNH_01867 1.99e-87 ywbC 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 glyoxalase
NIIKMLNH_01868 8.38e-160 ywbB - - S - - - Protein of unknown function (DUF2711)
NIIKMLNH_01869 1.1e-313 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NIIKMLNH_01870 0.0 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
NIIKMLNH_01871 1.45e-312 sacX 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NIIKMLNH_01872 2.6e-195 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
NIIKMLNH_01873 6.53e-217 gspA - - M - - - General stress
NIIKMLNH_01874 7.35e-160 ywaF - - S - - - Integral membrane protein
NIIKMLNH_01875 3.57e-114 ywaE - - K - - - Transcriptional regulator
NIIKMLNH_01876 7.11e-294 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NIIKMLNH_01877 0.0 ywaD 3.4.11.10, 3.4.11.6 - S ko:K19701 - ko00000,ko01000,ko01002 PA domain
NIIKMLNH_01878 2.52e-149 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 protein conserved in bacteria
NIIKMLNH_01879 4.89e-211 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
NIIKMLNH_01880 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NIIKMLNH_01881 1.14e-297 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 membrane protein involved in D-alanine export
NIIKMLNH_01882 6.83e-50 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NIIKMLNH_01883 4.09e-294 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NIIKMLNH_01884 2.39e-177 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
NIIKMLNH_01885 3.07e-263 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
NIIKMLNH_01886 0.0 licH 3.2.1.86 GT4 G ko:K01222 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
NIIKMLNH_01887 1.58e-50 licA 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NIIKMLNH_01888 0.0 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NIIKMLNH_01889 1.89e-67 licB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 transporter subunit IIB
NIIKMLNH_01890 0.0 licR - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
NIIKMLNH_01891 8.94e-28 yxzF - - - - - - -
NIIKMLNH_01892 3.23e-145 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
NIIKMLNH_01893 0.0 katX 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
NIIKMLNH_01894 3.93e-271 yxlH - - EGP - - - Major Facilitator Superfamily
NIIKMLNH_01895 1.61e-178 yxlG - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NIIKMLNH_01896 2.75e-98 yxlF - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NIIKMLNH_01897 1.81e-94 yxlF - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NIIKMLNH_01898 1.04e-37 yxlE - - S - - - Phospholipase_D-nuclease N-terminal
NIIKMLNH_01899 1.63e-39 - - - - - - - -
NIIKMLNH_01900 1.3e-60 yxlC - - S - - - Family of unknown function (DUF5345)
NIIKMLNH_01901 2.6e-124 sigY - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NIIKMLNH_01902 0.0 yxlA - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
NIIKMLNH_01903 1.77e-200 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NIIKMLNH_01904 0.0 cydD - - V ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding protein
NIIKMLNH_01905 0.0 cydC - - V ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding
NIIKMLNH_01906 1.16e-243 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase, subunit II
NIIKMLNH_01907 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
NIIKMLNH_01908 2.67e-308 cimH - - C - - - COG3493 Na citrate symporter
NIIKMLNH_01909 0.0 - - - O - - - Peptidase family M48
NIIKMLNH_01911 5.28e-199 yxkH - - G - - - Polysaccharide deacetylase
NIIKMLNH_01912 3.44e-261 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NIIKMLNH_01913 4.54e-209 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
NIIKMLNH_01914 0.0 aldY 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NIIKMLNH_01915 2.29e-188 yxkD - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
NIIKMLNH_01916 4.99e-100 yxkC - - S - - - Domain of unknown function (DUF4352)
NIIKMLNH_01917 6.06e-251 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
NIIKMLNH_01918 2.68e-100 - - - S - - - Protein of unknown function (DUF1453)
NIIKMLNH_01919 6.98e-243 - - - T - - - Signal transduction histidine kinase
NIIKMLNH_01920 1.05e-145 - - - K ko:K02479 - ko00000,ko02022 helix_turn_helix, Lux Regulon
NIIKMLNH_01921 3.16e-298 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
NIIKMLNH_01924 2.88e-111 yxjI - - S - - - LURP-one-related
NIIKMLNH_01925 1.75e-276 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
NIIKMLNH_01926 5.42e-276 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
NIIKMLNH_01927 1.67e-175 yxjF 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
NIIKMLNH_01928 5.91e-151 scoB 2.8.3.5 - I ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
NIIKMLNH_01929 5.43e-167 scoA 2.8.3.5 - I ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NIIKMLNH_01930 5.14e-112 yxjC - - EG - - - COG2610 H gluconate symporter and related permeases
NIIKMLNH_01931 6.4e-172 yxjC - - EG - - - COG2610 H gluconate symporter and related permeases
NIIKMLNH_01932 2.67e-189 yxjB 2.1.1.187 - Q ko:K00563 - ko00000,ko01000,ko03009 Methyltransferase domain
NIIKMLNH_01934 1.72e-268 nupG - - F ko:K16323 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NIIKMLNH_01935 8.1e-131 - - - T - - - Domain of unknown function (DUF4163)
NIIKMLNH_01936 2.28e-63 yxiS - - - - - - -
NIIKMLNH_01937 0.0 katE 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
NIIKMLNH_01938 8.66e-139 citH - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
NIIKMLNH_01939 6.8e-121 citH - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
NIIKMLNH_01940 4.35e-184 bglS - - M - - - licheninase activity
NIIKMLNH_01941 5.66e-193 licT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
NIIKMLNH_01942 2.75e-145 - - - - - - - -
NIIKMLNH_01943 9.34e-293 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 COG2270 Permeases of the major facilitator superfamily
NIIKMLNH_01944 0.0 dbpA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
NIIKMLNH_01945 8.65e-275 - - - E - - - GDSL-like Lipase/Acylhydrolase
NIIKMLNH_01946 4.05e-69 - - - K - - - Transcriptional regulator PadR-like family
NIIKMLNH_01947 7.27e-76 - - - S - - - Protein of unknown function (DUF2812)
NIIKMLNH_01950 7.02e-59 yxiJ - - S - - - YxiJ-like protein
NIIKMLNH_01954 1.83e-43 - - - - - - - -
NIIKMLNH_01955 6.27e-106 yxiI - - S - - - Protein of unknown function (DUF2716)
NIIKMLNH_01956 1.98e-172 - - - - - - - -
NIIKMLNH_01957 8.06e-90 yxiG - - - - - - -
NIIKMLNH_01958 1.48e-47 - - - - - - - -
NIIKMLNH_01960 2.07e-210 yxxF - - EG - - - EamA-like transporter family
NIIKMLNH_01961 6.99e-94 yxiE - - T - - - Belongs to the universal stress protein A family
NIIKMLNH_01962 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NIIKMLNH_01963 0.0 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NIIKMLNH_01964 2.13e-64 - - - - - - - -
NIIKMLNH_01965 2.4e-80 - - - - - - - -
NIIKMLNH_01966 4.49e-37 - - - - - - - -
NIIKMLNH_01967 1.55e-54 - - - - - - - -
NIIKMLNH_01968 9.35e-74 - - - - - - - -
NIIKMLNH_01969 6.36e-277 - - - S ko:K21493 - ko00000,ko01000,ko02048 nuclease activity
NIIKMLNH_01970 5.43e-52 yxiC - - S - - - Family of unknown function (DUF5344)
NIIKMLNH_01971 1.78e-35 - - - S - - - Domain of unknown function (DUF5082)
NIIKMLNH_01972 0.0 - - - L - - - HKD family nuclease
NIIKMLNH_01973 1.23e-78 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
NIIKMLNH_01974 2.2e-193 - - - L - - - Protein of unknown function (DUF2726)
NIIKMLNH_01975 0.0 yxiA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
NIIKMLNH_01976 7.02e-103 hutP - - K ko:K09683 - ko00000,ko03000 Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
NIIKMLNH_01977 0.0 hutH 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Histidine ammonia-lyase
NIIKMLNH_01978 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NIIKMLNH_01979 7.47e-298 hutI 3.5.2.7 - Q ko:K01468 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Imidazolone-5-propionate hydrolase
NIIKMLNH_01980 2.58e-226 hutG 3.5.3.8 - E ko:K01479 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
NIIKMLNH_01981 0.0 ybgF - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
NIIKMLNH_01982 8.11e-299 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
NIIKMLNH_01983 2.72e-263 nupC - - F ko:K11535 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NIIKMLNH_01984 8.3e-150 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NIIKMLNH_01985 1.22e-221 deoR - - K ko:K05346 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
NIIKMLNH_01986 1.51e-196 - - - S - - - Domain of Unknown Function (DUF1206)
NIIKMLNH_01987 1.05e-253 eutH - - E ko:K04023 - ko00000 Ethanolamine utilisation protein, EutH
NIIKMLNH_01988 2.69e-310 yxeQ - - S - - - MmgE/PrpD family
NIIKMLNH_01989 9.65e-271 yxeP - - E ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
NIIKMLNH_01990 9.69e-171 yxeO - - P ko:K16960,ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NIIKMLNH_01991 3e-148 yxeN - - P ko:K10009,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
NIIKMLNH_01992 4.3e-186 yxeM - - M ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
NIIKMLNH_01993 5.16e-120 yxeL - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NIIKMLNH_01994 0.0 yxeK - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NIIKMLNH_01996 2.24e-236 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
NIIKMLNH_01997 2.71e-192 yxeH - - S - - - hydrolases of the HAD superfamily
NIIKMLNH_02000 7.32e-42 yxeE - - - - - - -
NIIKMLNH_02001 7.57e-28 yxeD - - - - - - -
NIIKMLNH_02002 3.93e-90 - - - - - - - -
NIIKMLNH_02003 1.43e-224 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NIIKMLNH_02004 1.41e-75 yxeA - - S - - - Protein of unknown function (DUF1093)
NIIKMLNH_02005 0.0 yxdM - - V ko:K11636 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
NIIKMLNH_02006 5.21e-179 yxdL - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NIIKMLNH_02007 3.67e-229 yxdK 2.7.13.3 - T ko:K11633 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NIIKMLNH_02008 2.8e-160 yxdJ - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NIIKMLNH_02009 2.83e-204 fbaA 4.1.2.13, 4.1.2.29 - F ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
NIIKMLNH_02010 2.19e-186 iolI 5.3.99.11 - G ko:K06606 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
NIIKMLNH_02011 1.08e-212 iolH - - G ko:K06605 - ko00000 Xylose isomerase-like TIM barrel
NIIKMLNH_02012 1.55e-251 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
NIIKMLNH_02013 8.46e-298 iolF - - EGP ko:K06610 - ko00000,ko02000 Major facilitator superfamily
NIIKMLNH_02014 8.63e-223 iolE 4.2.1.44 - G ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
NIIKMLNH_02015 0.0 iolD 3.7.1.22 - E ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
NIIKMLNH_02016 1.01e-226 iolC 2.7.1.92 - G ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
NIIKMLNH_02017 1.41e-199 iolB 5.3.1.30 - G ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
NIIKMLNH_02018 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NIIKMLNH_02019 1.56e-177 iolR - - K ko:K06608,ko:K11534 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
NIIKMLNH_02020 1.74e-224 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
NIIKMLNH_02022 2.04e-64 yxcD - - S - - - Protein of unknown function (DUF2653)
NIIKMLNH_02024 5.72e-117 - - - S - - - CGNR zinc finger
NIIKMLNH_02025 9.41e-105 - - - T - - - HPP family
NIIKMLNH_02026 2.8e-311 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NIIKMLNH_02027 0.0 htpG - - O ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Molecular chaperone. Has ATPase activity
NIIKMLNH_02029 1.14e-190 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
NIIKMLNH_02030 2.84e-263 yxbF - - K - - - Bacterial regulatory proteins, tetR family
NIIKMLNH_02031 2.8e-312 aldX 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
NIIKMLNH_02032 3.89e-30 yxaI - - S - - - membrane protein domain
NIIKMLNH_02033 7.49e-137 yxaL - - S - - - PQQ-like domain
NIIKMLNH_02034 8.92e-80 - - - S - - - Family of unknown function (DUF5391)
NIIKMLNH_02035 4.03e-99 yxaI - - S - - - membrane protein domain
NIIKMLNH_02036 5.11e-284 - - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
NIIKMLNH_02037 6.05e-250 - 1.13.11.24 - S ko:K07155 - ko00000,ko01000 AraC-like ligand binding domain
NIIKMLNH_02038 3.22e-129 yxaF - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
NIIKMLNH_02039 1.23e-254 yxnA - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
NIIKMLNH_02040 6.83e-94 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
NIIKMLNH_02041 5.1e-78 - - - S ko:K06518 - ko00000,ko02000 LrgA family
NIIKMLNH_02042 1.27e-152 yxaC - - M - - - effector of murein hydrolase
NIIKMLNH_02043 3.62e-245 - - - GM ko:K19426 - ko00000,ko01000 Polysaccharide pyruvyl transferase
NIIKMLNH_02044 4.91e-123 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
NIIKMLNH_02045 5.93e-105 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
NIIKMLNH_02046 3.63e-163 gntR - - K ko:K11476 - ko00000,ko03000 transcriptional
NIIKMLNH_02047 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
NIIKMLNH_02048 1.18e-294 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
NIIKMLNH_02049 0.0 gntZ 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NIIKMLNH_02050 9.33e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Alkyl hydroperoxide reductase
NIIKMLNH_02051 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 Alkyl hydroperoxide reductase
NIIKMLNH_02052 1.58e-237 - - - S - - - Polysaccharide pyruvyl transferase
NIIKMLNH_02053 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NIIKMLNH_02054 9.18e-23 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NIIKMLNH_02055 3.94e-159 yydK - - K ko:K03489 - ko00000,ko03000 Transcriptional regulator
NIIKMLNH_02056 3.04e-24 - - - - - - - -
NIIKMLNH_02057 5.49e-152 - - - S ko:K16916 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
NIIKMLNH_02058 8.4e-143 - - - P ko:K16917 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NIIKMLNH_02059 3.65e-172 - - - O ko:K16922 - ko00000,ko01002 Peptidase M50
NIIKMLNH_02060 2.24e-236 - - - S - - - Radical SAM superfamily
NIIKMLNH_02061 8.12e-17 - - - - - - - -
NIIKMLNH_02062 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Firmicute fructose-1,6-bisphosphatase
NIIKMLNH_02064 5e-106 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NIIKMLNH_02066 3.72e-86 - - - - - - - -
NIIKMLNH_02067 1.81e-297 yycR 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
NIIKMLNH_02069 1.3e-40 yycQ - - S - - - Protein of unknown function (DUF2651)
NIIKMLNH_02070 5.57e-269 yycP - - - - - - -
NIIKMLNH_02071 1.32e-166 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
NIIKMLNH_02072 4.32e-110 yycN - - K - - - Acetyltransferase
NIIKMLNH_02073 1.23e-238 - - - S - - - aspartate phosphatase
NIIKMLNH_02075 3.22e-213 rocF 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
NIIKMLNH_02076 0.0 rocE - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
NIIKMLNH_02077 3.38e-293 rocD 2.6.1.13 - E ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko01007 Catalyzes the interconversion of ornithine to glutamate semialdehyde
NIIKMLNH_02078 0.0 rocR - - KT ko:K06714 - ko00000,ko03000 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
NIIKMLNH_02079 5.45e-278 yyxA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NIIKMLNH_02080 1.15e-190 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
NIIKMLNH_02081 1.2e-200 yycI - - S - - - protein conserved in bacteria
NIIKMLNH_02082 0.0 yycH - - S - - - protein conserved in bacteria
NIIKMLNH_02083 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NIIKMLNH_02084 1.45e-172 yycF - - T ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NIIKMLNH_02089 1.29e-314 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NIIKMLNH_02090 1.02e-71 yycE - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NIIKMLNH_02091 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
NIIKMLNH_02092 3.48e-40 yycD - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
NIIKMLNH_02094 1.89e-22 yycC - - K - - - YycC-like protein
NIIKMLNH_02095 4.19e-283 yycB - - P ko:K03449 - ko00000,ko02000 COG2807 Cyanate permease
NIIKMLNH_02096 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NIIKMLNH_02097 2.74e-96 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
NIIKMLNH_02098 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
NIIKMLNH_02099 5.23e-205 yybS - - S - - - membrane
NIIKMLNH_02101 2.89e-110 cotF - - M ko:K06329 - ko00000 Spore coat protein
NIIKMLNH_02102 6.68e-90 yybR - - K - - - Transcriptional regulator
NIIKMLNH_02103 4.89e-210 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
NIIKMLNH_02104 7.84e-91 - - - - - - - -
NIIKMLNH_02106 1.01e-307 yybO - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
NIIKMLNH_02107 5.74e-34 - - - K - - - TipAS antibiotic-recognition domain
NIIKMLNH_02108 7.9e-73 - - - K - - - TipAS antibiotic-recognition domain
NIIKMLNH_02109 3.96e-181 - - - - - - - -
NIIKMLNH_02110 5.02e-87 - - - S - - - SnoaL-like domain
NIIKMLNH_02111 2.16e-164 - - - S - - - Metallo-beta-lactamase superfamily
NIIKMLNH_02112 4.54e-100 yybA - - K - - - transcriptional
NIIKMLNH_02113 1.16e-92 yjcF - - S - - - Acetyltransferase (GNAT) domain
NIIKMLNH_02114 4.28e-125 yyaS - - S ko:K07149 - ko00000 Membrane
NIIKMLNH_02115 1.91e-119 - - - K ko:K19273 - ko00000,ko01000,ko01504 Acetyltransferase (GNAT) domain
NIIKMLNH_02116 7.41e-86 - - - S - - - YjbR
NIIKMLNH_02117 6.31e-139 yyaP - - H - - - RibD C-terminal domain
NIIKMLNH_02118 1.29e-18 yddB - - S - - - Conjugative transposon protein TcpC
NIIKMLNH_02121 1.3e-58 yddA - - - - - - -
NIIKMLNH_02126 0.0 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
NIIKMLNH_02127 6.73e-212 yyaK - - S ko:K07052 - ko00000 CAAX protease self-immunity
NIIKMLNH_02128 0.0 - - - EGP ko:K08369 - ko00000,ko02000 Major facilitator superfamily
NIIKMLNH_02129 1.33e-129 vatD 2.3.1.28, 2.3.1.79 - S ko:K00638,ko:K00661,ko:K18234 - br01600,ko00000,ko01000,ko01504 Bacterial transferase hexapeptide (six repeats)
NIIKMLNH_02130 1.2e-88 yyaH 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NIIKMLNH_02131 1.61e-225 ccpB - - K - - - Transcriptional regulator
NIIKMLNH_02132 2.07e-187 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
NIIKMLNH_02133 4.25e-49 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NIIKMLNH_02134 1.81e-103 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NIIKMLNH_02135 1.01e-61 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
NIIKMLNH_02136 5.65e-256 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NIIKMLNH_02137 0.0 yyaE - - C - - - Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NIIKMLNH_02138 7.41e-45 yyzM - - S - - - protein conserved in bacteria
NIIKMLNH_02139 2.17e-226 yyaD - - S - - - Membrane
NIIKMLNH_02140 4.53e-145 yyaC - - S - - - Sporulation protein YyaC
NIIKMLNH_02141 3.96e-191 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
NIIKMLNH_02142 4.79e-173 soj - - D ko:K03496 - ko00000,ko03036,ko04812 COG1192 ATPases involved in chromosome partitioning
NIIKMLNH_02143 4.95e-72 - - - S - - - Bacterial PH domain
NIIKMLNH_02144 9e-193 noc - - D ko:K03497 - ko00000,ko03000,ko03036,ko04812 Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
NIIKMLNH_02145 1.01e-167 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
NIIKMLNH_02146 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NIIKMLNH_02147 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NIIKMLNH_02148 1.83e-141 jag - - S ko:K06346 - ko00000 single-stranded nucleic acid binding R3H
NIIKMLNH_02149 9.29e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NIIKMLNH_02150 8.1e-71 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NIIKMLNH_02151 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NIIKMLNH_02152 1.71e-263 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NIIKMLNH_02153 2.24e-45 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
NIIKMLNH_02154 1.85e-263 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NIIKMLNH_02155 1.25e-51 yaaB - - S - - - Domain of unknown function (DUF370)
NIIKMLNH_02156 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NIIKMLNH_02157 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NIIKMLNH_02158 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
NIIKMLNH_02161 4.14e-230 yaaC - - S - - - YaaC-like Protein
NIIKMLNH_02162 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
NIIKMLNH_02163 3.75e-316 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
NIIKMLNH_02164 3.7e-202 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
NIIKMLNH_02165 3.34e-138 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
NIIKMLNH_02166 3.5e-289 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NIIKMLNH_02168 3.72e-159 dck 2.7.1.74, 2.7.1.76 - F ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko01000 Deoxycytidine kinase
NIIKMLNH_02169 5.73e-149 dgk 2.7.1.113 - F ko:K15518 ko00230,map00230 ko00000,ko00001,ko01000 Deoxyguanosine kinase
NIIKMLNH_02170 1.48e-275 yaaH - - M ko:K06306 - ko00000 Glycoside Hydrolase Family
NIIKMLNH_02171 3.26e-124 yaaI - - Q - - - COG1335 Amidases related to nicotinamidase
NIIKMLNH_02172 2.47e-107 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NIIKMLNH_02173 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NIIKMLNH_02174 8.75e-55 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NIIKMLNH_02175 8.53e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NIIKMLNH_02176 1.55e-42 yaaL - - S - - - Protein of unknown function (DUF2508)
NIIKMLNH_02177 1.25e-47 bofA - - S ko:K06317 - ko00000 Sigma-K factor-processing regulatory protein BofA
NIIKMLNH_02178 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
NIIKMLNH_02181 2.21e-42 csfB - - S - - - Inhibitor of sigma-G Gin
NIIKMLNH_02182 3.83e-132 xpaC - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
NIIKMLNH_02183 1.69e-258 yaaN - - P - - - Belongs to the TelA family
NIIKMLNH_02184 0.0 yaaO - - E - - - Orn Lys Arg decarboxylase
NIIKMLNH_02185 4.67e-146 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NIIKMLNH_02186 1.02e-72 yaaQ - - S - - - protein conserved in bacteria
NIIKMLNH_02187 1.26e-95 yaaR - - S ko:K09770 - ko00000 protein conserved in bacteria
NIIKMLNH_02188 2.82e-235 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
NIIKMLNH_02189 6.33e-189 yaaT - - S - - - stage 0 sporulation protein
NIIKMLNH_02190 1.53e-56 yabA - - L - - - Involved in initiation control of chromosome replication
NIIKMLNH_02191 1.63e-177 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Conserved hypothetical protein 95
NIIKMLNH_02192 1.2e-64 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
NIIKMLNH_02193 2.95e-207 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NIIKMLNH_02194 1.51e-58 abrB - - K ko:K06284 - ko00000,ko03000 COG2002 Regulators of stationary sporulation gene expression
NIIKMLNH_02195 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NIIKMLNH_02196 5.9e-184 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD
NIIKMLNH_02197 4.1e-278 yabE - - T - - - protein conserved in bacteria
NIIKMLNH_02198 1.43e-125 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NIIKMLNH_02199 1.44e-198 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NIIKMLNH_02200 1.11e-198 yabG - - S ko:K06436 - ko00000 peptidase
NIIKMLNH_02201 5.32e-53 veg - - S - - - protein conserved in bacteria
NIIKMLNH_02202 3.96e-37 sspF - - S ko:K06423 - ko00000 DNA topological change
NIIKMLNH_02203 2.34e-207 ispE 2.7.1.148 - I ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NIIKMLNH_02204 4.66e-196 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
NIIKMLNH_02205 3.45e-83 yabJ 3.5.99.10 - J ko:K09022 - ko00000,ko01000 translation initiation inhibitor, yjgF family
NIIKMLNH_02206 2.45e-63 spoVG - - D ko:K06412 - ko00000 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
NIIKMLNH_02208 2.58e-309 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NIIKMLNH_02209 1.22e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NIIKMLNH_02210 1.45e-136 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NIIKMLNH_02211 8.28e-135 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NIIKMLNH_02212 5.24e-53 yabK - - S - - - Peptide ABC transporter permease
NIIKMLNH_02213 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NIIKMLNH_02214 5.88e-121 spoVT - - K ko:K04769 - ko00000,ko03000 stage V sporulation protein
NIIKMLNH_02215 0.0 yabM - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NIIKMLNH_02216 0.0 yabN 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
NIIKMLNH_02217 4.22e-50 yabO - - J - - - COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
NIIKMLNH_02218 1.91e-66 yabP - - S - - - Sporulation protein YabP
NIIKMLNH_02219 1.49e-137 yabQ - - S - - - spore cortex biosynthesis protein
NIIKMLNH_02220 1.2e-74 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
NIIKMLNH_02221 2.49e-82 yabR - - J ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
NIIKMLNH_02224 0.0 spoIIE 3.1.3.16 - KT ko:K06382 - ko00000,ko01000 stage II sporulation protein E
NIIKMLNH_02225 5.61e-168 yabS - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
NIIKMLNH_02226 1.63e-234 yabT 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 serine threonine protein kinase
NIIKMLNH_02227 0.0 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NIIKMLNH_02228 4.82e-121 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
NIIKMLNH_02229 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NIIKMLNH_02230 6.92e-189 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NIIKMLNH_02231 9.54e-208 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NIIKMLNH_02232 8.93e-172 yacD 5.2.1.8 - O ko:K07533 - ko00000,ko01000,ko03110 peptidyl-prolyl isomerase
NIIKMLNH_02233 1.54e-217 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
NIIKMLNH_02234 0.0 pabB 2.6.1.85 - EH ko:K01665 ko00790,map00790 ko00000,ko00001,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NIIKMLNH_02235 2.44e-136 pabA 2.6.1.85 - EH ko:K01664 ko00790,map00790 ko00000,ko00001,ko01000 Anthranilate synthase
NIIKMLNH_02236 1.08e-214 pabC 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 4-amino-4-deoxychorismate lyase
NIIKMLNH_02237 3.88e-204 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NIIKMLNH_02238 3.8e-80 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NIIKMLNH_02239 4.56e-115 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NIIKMLNH_02240 1.81e-41 yazB - - K - - - transcriptional
NIIKMLNH_02241 7.56e-242 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NIIKMLNH_02242 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
NIIKMLNH_02243 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
NIIKMLNH_02253 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
NIIKMLNH_02254 8.72e-100 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
NIIKMLNH_02255 2.36e-74 mcsA - - S ko:K19411 - ko00000 protein with conserved CXXC pairs
NIIKMLNH_02256 7.74e-257 mcsB 2.7.14.1 - E ko:K19405 - ko00000,ko01000 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
NIIKMLNH_02257 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
NIIKMLNH_02258 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NIIKMLNH_02259 3.8e-251 disA 2.7.7.85 - L ko:K07067 - ko00000,ko01000 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
NIIKMLNH_02260 2.57e-252 yacL - - S - - - COG4956 Integral membrane protein (PIN domain superfamily)
NIIKMLNH_02261 1.82e-162 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
NIIKMLNH_02262 2.59e-112 ispF 2.7.7.60, 4.6.1.12 - I ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
NIIKMLNH_02263 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NIIKMLNH_02264 1.91e-152 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Serine acetyltransferase
NIIKMLNH_02265 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
NIIKMLNH_02266 2.04e-95 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NIIKMLNH_02267 3.52e-173 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NIIKMLNH_02268 3.31e-114 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
NIIKMLNH_02269 3.27e-149 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
NIIKMLNH_02270 2.65e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NIIKMLNH_02271 1.37e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
NIIKMLNH_02272 3.4e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NIIKMLNH_02273 1.82e-162 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NIIKMLNH_02274 4.03e-104 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NIIKMLNH_02275 2.84e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NIIKMLNH_02276 5.1e-140 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
NIIKMLNH_02277 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NIIKMLNH_02278 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NIIKMLNH_02279 1.99e-44 rplGB - - J ko:K07590 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the eukaryotic ribosomal protein eL8 family
NIIKMLNH_02280 6.67e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NIIKMLNH_02281 4.85e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NIIKMLNH_02282 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NIIKMLNH_02283 2.01e-287 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NIIKMLNH_02284 9.05e-231 ybaC - - S - - - Alpha/beta hydrolase family
NIIKMLNH_02285 2.58e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
NIIKMLNH_02286 7.2e-144 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NIIKMLNH_02287 7.98e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
NIIKMLNH_02288 3.27e-58 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NIIKMLNH_02289 2.72e-200 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NIIKMLNH_02290 2.83e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NIIKMLNH_02291 9.23e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NIIKMLNH_02292 1.69e-151 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NIIKMLNH_02293 1.96e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NIIKMLNH_02294 1.88e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
NIIKMLNH_02295 1.64e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NIIKMLNH_02296 3.62e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NIIKMLNH_02297 1.43e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NIIKMLNH_02298 7.72e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NIIKMLNH_02299 1.43e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NIIKMLNH_02300 3.11e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NIIKMLNH_02301 4.47e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NIIKMLNH_02302 2.89e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NIIKMLNH_02303 9.16e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NIIKMLNH_02304 1.59e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
NIIKMLNH_02305 7.32e-95 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
NIIKMLNH_02306 5.7e-298 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NIIKMLNH_02307 2.51e-157 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NIIKMLNH_02308 2.32e-182 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
NIIKMLNH_02309 2.92e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NIIKMLNH_02310 2.45e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
NIIKMLNH_02311 1.09e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NIIKMLNH_02312 3.24e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NIIKMLNH_02313 7.01e-217 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NIIKMLNH_02314 4.27e-77 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
NIIKMLNH_02315 7.5e-200 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NIIKMLNH_02316 1.83e-193 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NIIKMLNH_02317 1.6e-177 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NIIKMLNH_02318 1.24e-181 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NIIKMLNH_02319 1.13e-102 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NIIKMLNH_02320 4.28e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
NIIKMLNH_02321 2.06e-184 ybaJ - - Q - - - Methyltransferase domain
NIIKMLNH_02322 2.54e-91 ybaK - - S - - - Protein of unknown function (DUF2521)
NIIKMLNH_02323 9.05e-170 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
NIIKMLNH_02324 1.1e-255 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
NIIKMLNH_02325 1.04e-122 gerD - - - ko:K06294 - ko00000 -
NIIKMLNH_02326 5.95e-133 kbaA - - S ko:K06349 - ko00000 Involved in the activation of the KinB signaling pathway of sporulation
NIIKMLNH_02327 2.49e-180 pdaB - - G - - - Polysaccharide deacetylase
NIIKMLNH_02328 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
NIIKMLNH_02335 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
NIIKMLNH_02336 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
NIIKMLNH_02337 0.0 ybaR - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
NIIKMLNH_02338 1.47e-200 ybaS - - S - - - Na -dependent transporter
NIIKMLNH_02339 1.33e-173 ybbA - - S ko:K07017 - ko00000 Putative esterase
NIIKMLNH_02340 1.01e-227 feuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NIIKMLNH_02341 2.88e-226 feuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NIIKMLNH_02342 5.12e-216 feuA - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Iron-uptake system-binding protein
NIIKMLNH_02343 0.0 ybbB - - K ko:K21701 - ko00000,ko03000 COG2207 AraC-type DNA-binding domain-containing proteins
NIIKMLNH_02344 2.33e-302 ybbC - - S - - - protein conserved in bacteria
NIIKMLNH_02345 0.0 ybbD 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
NIIKMLNH_02346 0.0 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the UPF0214 family
NIIKMLNH_02347 2.97e-303 ybbF 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NIIKMLNH_02348 5.43e-194 ybbH - - K - - - transcriptional
NIIKMLNH_02349 5.5e-209 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NIIKMLNH_02350 3.13e-114 ybbJ - - J - - - acetyltransferase
NIIKMLNH_02351 2.43e-100 ybbK - - S - - - Protein of unknown function (DUF523)
NIIKMLNH_02357 4.59e-127 sigW - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NIIKMLNH_02358 2.73e-152 rsiW - - K - - - Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
NIIKMLNH_02359 5.43e-189 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NIIKMLNH_02360 3.55e-291 ybbR - - S - - - protein conserved in bacteria
NIIKMLNH_02361 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NIIKMLNH_02362 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NIIKMLNH_02363 3.95e-222 alkA 3.2.2.21 - L ko:K01247,ko:K13529 ko03410,map03410 ko00000,ko00001,ko01000,ko03000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NIIKMLNH_02364 1.78e-152 adaA - - K ko:K13530 - ko00000,ko01000,ko03000,ko03400 Transcriptional regulator
NIIKMLNH_02365 1.06e-126 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NIIKMLNH_02366 0.0 ndhF 1.6.5.3 - CP ko:K05577 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
NIIKMLNH_02367 0.0 ybcC - - S ko:K09822 - ko00000 Belongs to the UPF0753 family
NIIKMLNH_02368 1.83e-118 ybcF - - P - - - carbonic anhydrase
NIIKMLNH_02369 1.6e-63 - - - - - - - -
NIIKMLNH_02370 3.6e-80 ybcI - - S - - - Uncharacterized conserved protein (DUF2294)
NIIKMLNH_02371 9.45e-67 - - - K - - - Helix-turn-helix domain
NIIKMLNH_02372 1.27e-255 ybcL - - EGP ko:K08164 - ko00000,ko02000 COG2814 Arabinose efflux permease
NIIKMLNH_02373 3.35e-73 - - - - - - - -
NIIKMLNH_02374 6.35e-230 - - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NIIKMLNH_02375 6.9e-158 - - - T ko:K02483 - ko00000,ko02022 Transcriptional regulatory protein, C terminal
NIIKMLNH_02376 1.08e-216 - - - T - - - His Kinase A (phospho-acceptor) domain
NIIKMLNH_02378 9.33e-177 ybdM 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 Protein tyrosine kinase
NIIKMLNH_02379 9e-194 ybdN - - - - - - -
NIIKMLNH_02380 1.42e-270 ybdO - - S - - - Domain of unknown function (DUF4885)
NIIKMLNH_02381 0.0 ybxG - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
NIIKMLNH_02382 5.46e-51 csgA - - S - - - Sigma-G-dependent sporulation-specific SASP protein
NIIKMLNH_02383 6.92e-41 ybxH - - S - - - Family of unknown function (DUF5370)
NIIKMLNH_02384 7.18e-191 ybxI 3.5.2.6 - V ko:K17838 ko01501,map01501 ko00000,ko00001,ko01000 beta-lactamase
NIIKMLNH_02385 3.8e-314 cypC 1.11.2.4 - Q ko:K15629 - ko00000,ko00199,ko01000 Cytochrome P450
NIIKMLNH_02386 1.11e-54 ybyB - - - - - - -
NIIKMLNH_02387 0.0 ybeC - - E - - - amino acid
NIIKMLNH_02388 5.52e-208 glpQ 3.1.3.1, 3.1.4.46 - C ko:K01113,ko:K01126 ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 glycerophosphoryl diester phosphodiesterase
NIIKMLNH_02389 0.0 glpT - - G ko:K02445 - ko00000,ko02000 -transporter
NIIKMLNH_02390 1.02e-46 - - - S - - - Protein of unknown function (DUF2651)
NIIKMLNH_02391 1e-216 ybfA - - K - - - FR47-like protein
NIIKMLNH_02392 9.18e-285 ybfB - - G - - - COG0477 Permeases of the major facilitator superfamily
NIIKMLNH_02394 0.0 ybfG - - M - - - Domain of unknown function (DUF1906)
NIIKMLNH_02395 6.15e-207 ybfH - - EG - - - EamA-like transporter family
NIIKMLNH_02396 7.39e-188 ybfI - - K - - - AraC-like ligand binding domain
NIIKMLNH_02397 7.62e-270 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NIIKMLNH_02398 2.39e-228 mpr - - M - - - Belongs to the peptidase S1B family
NIIKMLNH_02400 1.41e-211 - - - S - - - Alpha/beta hydrolase family
NIIKMLNH_02401 2.81e-123 pssA 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NIIKMLNH_02402 7.07e-112 ybfM - - S - - - SNARE associated Golgi protein
NIIKMLNH_02403 2.06e-188 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
NIIKMLNH_02404 1.58e-59 ybfN - - - - - - -
NIIKMLNH_02405 0.0 - - - S ko:K06880 - ko00000,ko01000,ko01504 Erythromycin esterase
NIIKMLNH_02406 1.16e-244 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
NIIKMLNH_02407 4.25e-273 gltP - - C ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NIIKMLNH_02408 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NIIKMLNH_02409 3.02e-174 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NIIKMLNH_02410 2.91e-165 - - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
NIIKMLNH_02412 1.46e-257 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
NIIKMLNH_02413 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
NIIKMLNH_02414 4.32e-232 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine
NIIKMLNH_02415 0.0 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
NIIKMLNH_02416 3.06e-238 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
NIIKMLNH_02417 5.88e-293 glnJ 2.7.13.3 - T ko:K07717 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NIIKMLNH_02418 5.76e-216 glnL - - T ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Regulator
NIIKMLNH_02419 4.1e-222 ycbC 4.2.1.41 - EM ko:K01707 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 5-dehydro-4-deoxyglucarate dehydratase activity
NIIKMLNH_02420 0.0 ycbD - - C ko:K22187 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NIIKMLNH_02421 0.0 gudP - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
NIIKMLNH_02422 0.0 gudD 4.2.1.40 - M ko:K01706 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
NIIKMLNH_02423 2.3e-161 ycbG - - K ko:K05799 - ko00000,ko03000 FCD
NIIKMLNH_02424 0.0 garD 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
NIIKMLNH_02425 1.43e-221 ycbJ - - S ko:K06979 - br01600,ko00000,ko00002,ko01504 Macrolide 2'-phosphotransferase
NIIKMLNH_02426 8.73e-33 rtpA - - K - - - Tryptophan RNA-binding attenuator protein inhibitory protein
NIIKMLNH_02427 6.77e-177 eamA1 - - EG - - - spore germination
NIIKMLNH_02428 2.61e-160 ycbL - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NIIKMLNH_02429 2.26e-216 ycbM - - T - - - Histidine kinase
NIIKMLNH_02430 3.74e-213 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NIIKMLNH_02431 2.87e-148 - - - S - - - ABC-2 family transporter protein
NIIKMLNH_02432 2.21e-76 ycbP - - S - - - Protein of unknown function (DUF2512)
NIIKMLNH_02433 5.22e-102 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
NIIKMLNH_02434 2.7e-174 ycbR - - T - - - vWA found in TerF C terminus
NIIKMLNH_02435 0.0 phoD 3.1.3.1 - P ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG3540 Phosphodiesterase alkaline phosphatase D
NIIKMLNH_02436 3.12e-38 tatAD - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
NIIKMLNH_02437 3.09e-159 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NIIKMLNH_02438 8.43e-155 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NIIKMLNH_02439 1.45e-260 ycbU - - E - - - Selenocysteine lyase
NIIKMLNH_02440 1.24e-302 lmrB - - EGP ko:K18926 - ko00000,ko00002,ko02000 the major facilitator superfamily
NIIKMLNH_02441 6.54e-132 lmrA - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
NIIKMLNH_02442 1.14e-255 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
NIIKMLNH_02443 1.63e-146 - 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
NIIKMLNH_02444 2.31e-73 - - - S - - - RDD family
NIIKMLNH_02445 1.18e-253 yccF - - K ko:K07039 - ko00000 SEC-C motif
NIIKMLNH_02446 8.04e-209 natK 2.7.13.3 - T ko:K11640 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
NIIKMLNH_02447 2.79e-162 natR - - T ko:K02477,ko:K11641 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
NIIKMLNH_02448 2.2e-170 natA 3.6.3.7 - CP ko:K01990,ko:K09697 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
NIIKMLNH_02449 1.27e-253 - - - CP ko:K09696 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
NIIKMLNH_02450 5.59e-221 yccK - - C - - - Aldo keto reductase
NIIKMLNH_02451 1.35e-241 ycdA - - S - - - Domain of unknown function (DUF5105)
NIIKMLNH_02452 0.0 ycdB - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NIIKMLNH_02453 0.0 ycdC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NIIKMLNH_02454 2.98e-120 - - - M ko:K17733 - ko00000,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
NIIKMLNH_02455 2.86e-248 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
NIIKMLNH_02456 5.63e-179 - 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
NIIKMLNH_02457 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
NIIKMLNH_02458 1.95e-221 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
NIIKMLNH_02459 2.32e-169 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
NIIKMLNH_02460 4.63e-173 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
NIIKMLNH_02461 2.83e-236 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NIIKMLNH_02462 2.64e-141 yceC 3.5.4.33 - T ko:K11991 - ko00000,ko01000,ko03016 proteins involved in stress response, homologs of TerZ and
NIIKMLNH_02463 8.9e-137 yceD - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
NIIKMLNH_02464 4.97e-138 yceE - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
NIIKMLNH_02465 1.18e-175 yceF - - P ko:K05794 - ko00000 Protein of unknown function (DUF475)
NIIKMLNH_02466 0.0 yceG - - S - - - Putative component of 'biosynthetic module'
NIIKMLNH_02467 4.21e-245 yceH - - P - - - Belongs to the TelA family
NIIKMLNH_02468 1.56e-277 yceI - - P ko:K08369 - ko00000,ko02000 Uncharacterised MFS-type transporter YbfB
NIIKMLNH_02469 2.68e-257 - - - EGP - - - Uncharacterised MFS-type transporter YbfB
NIIKMLNH_02470 4.82e-61 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
NIIKMLNH_02471 8.99e-293 opuAA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
NIIKMLNH_02472 2.1e-186 opuAB - - P ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
NIIKMLNH_02473 2.01e-210 opuAC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
NIIKMLNH_02474 1.55e-273 amhX - - S ko:K14665 - ko00000,ko01000,ko01002 amidohydrolase
NIIKMLNH_02475 0.0 ycgA - - S - - - Membrane
NIIKMLNH_02476 3.86e-105 ycgB - - - - - - -
NIIKMLNH_02477 0.0 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
NIIKMLNH_02478 2.06e-233 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
NIIKMLNH_02479 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
NIIKMLNH_02480 0.0 mdr - - EGP - - - the major facilitator superfamily
NIIKMLNH_02481 3.7e-101 ycgE - - K - - - helix_turn_helix multiple antibiotic resistance protein
NIIKMLNH_02482 3.37e-140 ycgF - - E - - - Lysine exporter protein LysE YggA
NIIKMLNH_02483 2.16e-194 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
NIIKMLNH_02484 0.0 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
NIIKMLNH_02485 7.6e-145 ycgI - - S ko:K09967 - ko00000 Domain of unknown function (DUF1989)
NIIKMLNH_02486 3.69e-191 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NIIKMLNH_02487 3.09e-139 tmrB - - S - - - AAA domain
NIIKMLNH_02489 1.05e-136 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NIIKMLNH_02490 5.27e-186 - - - Q - - - ubiE/COQ5 methyltransferase family
NIIKMLNH_02491 2.67e-224 ycgK - - K ko:K04761 ko02026,map02026 ko00000,ko00001,ko03000 LysR substrate binding domain
NIIKMLNH_02492 1.29e-230 cah 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 Acetyl xylan esterase (AXE1)
NIIKMLNH_02493 2.22e-186 ycgL - - S ko:K07074 - ko00000 Predicted nucleotidyltransferase
NIIKMLNH_02494 3.63e-218 ycgM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
NIIKMLNH_02495 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
NIIKMLNH_02496 2.64e-316 putP - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NIIKMLNH_02497 3.92e-288 ycgP - - QT - - - COG2508 Regulator of polyketide synthase expression
NIIKMLNH_02498 3.82e-195 ycgQ - - S ko:K08986 - ko00000 membrane
NIIKMLNH_02499 3.19e-187 ycgR - - S ko:K07089 - ko00000 permeases
NIIKMLNH_02500 8.45e-203 ycgS - - I - - - alpha/beta hydrolase fold
NIIKMLNH_02501 1.93e-241 ycgT 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
NIIKMLNH_02502 0.0 nasF 2.1.1.107, 4.2.1.75 - H ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
NIIKMLNH_02503 1.2e-74 nasE 1.7.1.15 - P ko:K00363 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Nitrite reductase
NIIKMLNH_02504 0.0 nasD 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NIIKMLNH_02505 0.0 nasC - - C ko:K00372 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NIIKMLNH_02506 0.0 nasB 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Assimilatory nitrate reductase (electron transfer subunit)
NIIKMLNH_02507 3.18e-282 nasA - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
NIIKMLNH_02508 1.22e-221 folE2 3.5.4.16 - S ko:K09007 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Converts GTP to 7,8-dihydroneopterin triphosphate
NIIKMLNH_02509 3.14e-130 - - - M - - - ErfK YbiS YcfS YnhG
NIIKMLNH_02510 1.08e-287 yciC - - S - - - GTPases (G3E family)
NIIKMLNH_02511 1.73e-148 yckA - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
NIIKMLNH_02512 1.53e-186 yckB - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
NIIKMLNH_02514 1.64e-98 yckC - - S - - - membrane
NIIKMLNH_02515 9.74e-67 yckD - - S - - - Protein of unknown function (DUF2680)
NIIKMLNH_02516 7.43e-58 - - - K - - - MarR family
NIIKMLNH_02517 9e-32 - - - - - - - -
NIIKMLNH_02518 1.16e-154 - - - S - - - AAA domain
NIIKMLNH_02519 0.0 yckE 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NIIKMLNH_02520 5.81e-92 nin - - S - - - Competence protein J (ComJ)
NIIKMLNH_02521 1.27e-96 nucA - - M - - - Deoxyribonuclease NucA/NucB
NIIKMLNH_02522 1.24e-266 tlpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
NIIKMLNH_02523 5.38e-125 hxlB 5.3.1.27 - G ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
NIIKMLNH_02524 9.74e-138 hxlA 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 3-hexulose-6-phosphate synthase
NIIKMLNH_02525 6.05e-86 hxlR - - K - - - transcriptional
NIIKMLNH_02526 0.0 srfAA - - Q ko:K15654,ko:K15655,ko:K16119 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NIIKMLNH_02527 0.0 srfAB - - Q ko:K15654,ko:K15655,ko:K16120 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NIIKMLNH_02528 0.0 srfAC - - Q ko:K15656,ko:K16121 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 COG1020 Non-ribosomal peptide synthetase modules and related proteins
NIIKMLNH_02529 7.77e-178 srfAD - - Q ko:K15657 ko02024,map02024 ko00000,ko00001,ko01008 thioesterase
NIIKMLNH_02530 2.66e-289 - - - EGP - - - Major Facilitator Superfamily
NIIKMLNH_02531 3.91e-118 - - - S - - - YcxB-like protein
NIIKMLNH_02532 1.33e-204 ycxC - - EG - - - EamA-like transporter family
NIIKMLNH_02533 0.0 ycxD - - K - - - GntR family transcriptional regulator
NIIKMLNH_02534 2.02e-146 sfp - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
NIIKMLNH_02535 8.71e-148 yczE - - S ko:K07149 - ko00000 membrane
NIIKMLNH_02536 2.04e-171 tcyC - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
NIIKMLNH_02537 4.6e-157 tcyB - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
NIIKMLNH_02538 3.03e-188 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
NIIKMLNH_02539 5.32e-209 yclA - - K ko:K21755 - ko00000,ko03000 LysR substrate binding domain
NIIKMLNH_02540 2.24e-140 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
NIIKMLNH_02541 0.0 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
NIIKMLNH_02542 9.86e-53 - 4.1.1.61 - S ko:K21759 ko00627,ko01120,ko01220,map00627,map01120,map01220 ko00000,ko00001,ko01000 response to toxic substance
NIIKMLNH_02543 1.45e-107 yclD - - - - - - -
NIIKMLNH_02544 2.06e-197 yclE 3.4.11.5 - S ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Alpha beta hydrolase
NIIKMLNH_02545 0.0 dtpT - - E ko:K03305 - ko00000 amino acid peptide transporter
NIIKMLNH_02546 0.0 yclG - - M - - - Pectate lyase superfamily protein
NIIKMLNH_02548 0.0 gerKA - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
NIIKMLNH_02549 3.21e-285 gerKC - - S ko:K06297 - ko00000 spore germination
NIIKMLNH_02550 3.33e-247 gerKB - - F ko:K06296 - ko00000,ko02000 Spore germination protein
NIIKMLNH_02551 3.39e-155 yclH - - P ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
NIIKMLNH_02552 1.07e-277 yclI - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease) YclI
NIIKMLNH_02553 6.39e-165 yclJ - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NIIKMLNH_02554 0.0 yclK - - T - - - HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
NIIKMLNH_02555 2.18e-97 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
NIIKMLNH_02557 1.58e-05 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
NIIKMLNH_02559 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
NIIKMLNH_02560 1.09e-205 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NIIKMLNH_02561 4.69e-211 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NIIKMLNH_02562 2.29e-175 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NIIKMLNH_02563 4.69e-212 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
NIIKMLNH_02564 0.0 ycnB - - EGP - - - the major facilitator superfamily
NIIKMLNH_02565 7.15e-199 ycnC - - K - - - Transcriptional regulator
NIIKMLNH_02566 2.12e-174 - 1.5.1.39 - C ko:K10678,ko:K19286 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 ko00000,ko00001,ko01000 Oxidoreductase
NIIKMLNH_02567 1.68e-60 ycnE - - S - - - Monooxygenase
NIIKMLNH_02568 6.51e-69 yczG - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
NIIKMLNH_02569 0.0 gabR - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NIIKMLNH_02570 1.33e-310 gabT 2.6.1.19, 2.6.1.22 - E ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NIIKMLNH_02571 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NIIKMLNH_02572 2.76e-169 - - - L ko:K07497 - ko00000 Molecular Function DNA binding, Biological Process DNA recombination
NIIKMLNH_02573 7.42e-144 - - - V ko:K20485 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 ABC-type multidrug transport system, ATPase and permease
NIIKMLNH_02577 1.67e-190 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
NIIKMLNH_02578 2.69e-183 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NIIKMLNH_02579 3.99e-134 ycnI - - S - - - protein conserved in bacteria
NIIKMLNH_02580 0.0 ycnJ - - P ko:K14166 - ko00000,ko02000 protein, homolog of Cu resistance protein CopC
NIIKMLNH_02581 1e-136 ycnK - - K ko:K21601 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
NIIKMLNH_02582 4.67e-75 - - - - - - - -
NIIKMLNH_02583 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG2213 Phosphotransferase system, mannitol-specific IIBC component
NIIKMLNH_02584 8.3e-95 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
NIIKMLNH_02585 2.44e-265 mtlD 1.1.1.17 - G ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 COG0246 Mannitol-1-phosphate altronate dehydrogenases
NIIKMLNH_02586 8.33e-256 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Tartrate dehydrogenase
NIIKMLNH_02587 3.63e-124 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
NIIKMLNH_02588 5.45e-112 - - - Q - - - COG0412 Dienelactone hydrolase and related enzymes
NIIKMLNH_02589 2.29e-88 ycsD 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
NIIKMLNH_02591 1.9e-177 ycsE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
NIIKMLNH_02592 1.1e-180 ycsF - - S ko:K07160 - ko00000 Belongs to the UPF0271 (lamB) family
NIIKMLNH_02593 2.78e-273 ycsG - - P - - - COG1914 Mn2 and Fe2 transporters of the NRAMP family
NIIKMLNH_02594 1.65e-188 ycsI - - S - - - Belongs to the D-glutamate cyclase family
NIIKMLNH_02595 1.97e-170 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
NIIKMLNH_02596 1.29e-234 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
NIIKMLNH_02597 1.55e-170 kipR - - K - - - Transcriptional regulator
NIIKMLNH_02598 4.69e-151 ycsK - - E - - - anatomical structure formation involved in morphogenesis
NIIKMLNH_02600 8.97e-65 yczJ - - S - - - biosynthesis
NIIKMLNH_02601 0.0 pbpC 3.4.16.4 - M ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 Penicillin-binding Protein
NIIKMLNH_02602 1e-218 ycsN - - S - - - Oxidoreductase
NIIKMLNH_02603 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 transcriptional regulator, MtlR
NIIKMLNH_02604 0.0 ydaB - - IQ - - - acyl-CoA ligase
NIIKMLNH_02605 1.17e-126 ydaC - - Q - - - Methyltransferase domain
NIIKMLNH_02606 1.07e-206 ydaD - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NIIKMLNH_02607 2.75e-125 ydaE 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
NIIKMLNH_02608 1.1e-132 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NIIKMLNH_02609 1.06e-100 ydaG - - S - - - general stress protein
NIIKMLNH_02610 1.87e-178 amj - - U - - - Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
NIIKMLNH_02611 1.09e-61 ydzA - - EGP - - - Domain of unknown function (DUF3817)
NIIKMLNH_02612 3.95e-98 lrpC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
NIIKMLNH_02613 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NIIKMLNH_02614 9.49e-262 ydaJ - - M - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
NIIKMLNH_02615 6.34e-193 ydaK - - T - - - Diguanylate cyclase, GGDEF domain
NIIKMLNH_02616 0.0 ydaL - - S - - - Uncharacterized protein conserved in bacteria (DUF2334)
NIIKMLNH_02617 1.12e-303 ydaM - - M - - - Glycosyl transferase family group 2
NIIKMLNH_02618 0.0 ydaN - - S - - - Bacterial cellulose synthase subunit
NIIKMLNH_02619 0.0 ydaO - - E - - - amino acid
NIIKMLNH_02620 5.98e-100 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
NIIKMLNH_02621 0.0 ydaP 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
NIIKMLNH_02622 7.18e-52 - - - - - - - -
NIIKMLNH_02623 3.9e-286 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
NIIKMLNH_02624 1.67e-42 ydaS - - S - - - membrane
NIIKMLNH_02625 2.25e-100 ydaT - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
NIIKMLNH_02626 2.05e-188 ydbA - - P - - - EcsC protein family
NIIKMLNH_02627 8.37e-11 gsiB - - S ko:K06884 - ko00000 general stress protein
NIIKMLNH_02628 7.58e-79 ydbB - - G - - - Cupin domain
NIIKMLNH_02629 1.28e-82 ydbC - - S - - - Domain of unknown function (DUF4937
NIIKMLNH_02630 6.41e-197 ydbD - - P ko:K07217 - ko00000 Catalase
NIIKMLNH_02631 3.66e-253 dctB - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
NIIKMLNH_02632 0.0 dctS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
NIIKMLNH_02633 4.82e-155 dctR - - T ko:K02475,ko:K11692 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
NIIKMLNH_02634 6.29e-290 dctA - - U ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NIIKMLNH_02635 1.32e-230 ydbI - - S - - - AI-2E family transporter
NIIKMLNH_02636 4.59e-219 ydbJ - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NIIKMLNH_02637 2.99e-159 ydbK - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NIIKMLNH_02638 9.32e-70 ydbL - - - - - - -
NIIKMLNH_02639 2.49e-278 ydbM - - I - - - acyl-CoA dehydrogenase
NIIKMLNH_02640 1.49e-26 - - - S - - - Fur-regulated basic protein B
NIIKMLNH_02642 2.72e-202 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NIIKMLNH_02643 4.19e-75 ydbP - - CO - - - Thioredoxin
NIIKMLNH_02644 8.43e-256 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
NIIKMLNH_02645 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NIIKMLNH_02646 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NIIKMLNH_02647 2.12e-107 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
NIIKMLNH_02648 0.0 ydbT - - S ko:K08981 - ko00000 Membrane
NIIKMLNH_02649 3.6e-139 ydcA - - S - - - membrane protein (homolog of Drosophila rhomboid)
NIIKMLNH_02650 1.32e-76 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NIIKMLNH_02651 4.66e-234 ydcC - - M - - - COG2834 Outer membrane lipoprotein-sorting protein
NIIKMLNH_02652 1.77e-282 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NIIKMLNH_02653 9.49e-57 ndoAI - - K ko:K07723 - ko00000,ko02048,ko03000 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
NIIKMLNH_02654 4.34e-75 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
NIIKMLNH_02655 8.58e-184 rsbR - - T ko:K17763 - ko00000,ko03021 Positive regulator of sigma-B
NIIKMLNH_02656 1.8e-74 rsbS - - T ko:K17762 - ko00000,ko03021 antagonist
NIIKMLNH_02657 2.45e-89 rsbT 2.7.11.1 - T ko:K17752 - ko00000,ko01000,ko01001,ko03021 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
NIIKMLNH_02658 1.08e-242 rsbU 3.1.3.3 - KT ko:K07315 - ko00000,ko01000,ko03021 phosphatase
NIIKMLNH_02659 3.98e-70 rsbV - - T ko:K04749 - ko00000,ko03021 Belongs to the anti-sigma-factor antagonist family
NIIKMLNH_02660 8.3e-110 rsbW 2.7.11.1 - F ko:K04757 - ko00000,ko01000,ko01001,ko03021 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
NIIKMLNH_02661 1.55e-178 sigB - - K ko:K03090 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NIIKMLNH_02662 2.17e-140 rsbX 3.1.3.3 - KT ko:K05518 - ko00000,ko01000,ko03021 Sigma factor PP2C-like phosphatases
NIIKMLNH_02666 1.32e-106 ydcG - - S - - - EVE domain
NIIKMLNH_02667 1.79e-100 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
NIIKMLNH_02668 0.0 tex - - K ko:K06959 - ko00000 COG2183 Transcriptional accessory protein
NIIKMLNH_02669 3.74e-108 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
NIIKMLNH_02677 1.47e-268 ydcL - - L - - - Belongs to the 'phage' integrase family
NIIKMLNH_02678 4.73e-118 - - - E - - - IrrE N-terminal-like domain
NIIKMLNH_02679 1.91e-81 - - - K - - - Transcriptional
NIIKMLNH_02680 8.96e-24 - - - - - - - -
NIIKMLNH_02681 9.17e-54 - - - - - - - -
NIIKMLNH_02683 6.04e-43 - - - S - - - Bacterial protein of unknown function (DUF961)
NIIKMLNH_02684 1.33e-119 - - - M - - - Cysteine-rich secretory protein family
NIIKMLNH_02685 0.0 ydcQ - - D ko:K03466 - ko00000,ko03036 Ftsk spoiiie family protein
NIIKMLNH_02686 1.9e-256 nicK - - L ko:K07467 - ko00000 Replication initiation factor
NIIKMLNH_02688 1.72e-54 yddA - - - - - - -
NIIKMLNH_02691 7.6e-216 yddB - - S - - - Conjugative transposon protein TcpC
NIIKMLNH_02692 4.84e-54 yddC - - - - - - -
NIIKMLNH_02693 2.06e-119 yddD - - S - - - TcpE family
NIIKMLNH_02694 0.0 yddE - - S - - - AAA-like domain
NIIKMLNH_02695 1.34e-72 - - - S - - - Domain of unknown function (DUF1874)
NIIKMLNH_02696 0.0 yddG - - S - - - maturation of SSU-rRNA
NIIKMLNH_02697 7.54e-240 yddH - - M - - - Lysozyme-like
NIIKMLNH_02698 4.01e-105 yddI - - - - - - -
NIIKMLNH_02699 2.08e-57 yddJ - - S - - - Domain of unknown function with cystatin-like fold (DUF4467)
NIIKMLNH_02700 5.53e-110 - - - J - - - Domain of unknown function (DUF4209)
NIIKMLNH_02701 5.63e-91 - - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
NIIKMLNH_02705 2.33e-239 - - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NIIKMLNH_02706 8.15e-94 lrpA - - K ko:K03719 - ko00000,ko03000,ko03036 transcriptional
NIIKMLNH_02707 4.21e-100 lrpB - - K ko:K03719 - ko00000,ko03000,ko03036 transcriptional
NIIKMLNH_02708 1.62e-128 yddQ - - Q - - - Isochorismatase family
NIIKMLNH_02709 1.34e-184 yddR - - S - - - Zn-dependent hydrolases of the beta-lactamase fold
NIIKMLNH_02710 7.52e-285 ydeG3 - - EGP - - - Major Facilitator Superfamily
NIIKMLNH_02711 2.89e-84 - - - L - - - HNH nucleases
NIIKMLNH_02712 3.35e-245 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
NIIKMLNH_02713 4.22e-41 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock
NIIKMLNH_02714 3.57e-103 ydeB - - K ko:K07736 - ko00000,ko03000 Transcription factor
NIIKMLNH_02715 1.47e-211 - - - K - - - AraC-like ligand binding domain
NIIKMLNH_02716 7.92e-221 ydeD - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NIIKMLNH_02717 9.2e-210 ydeE - - K ko:K13653 - ko00000,ko03000 AraC family transcriptional regulator
NIIKMLNH_02718 6.12e-23 - - - K - - - COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NIIKMLNH_02719 1.39e-291 - - - K - - - COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NIIKMLNH_02720 2.67e-277 ydeG - - EGP - - - Major facilitator superfamily
NIIKMLNH_02721 7.89e-71 ydeH - - - - - - -
NIIKMLNH_02722 6.71e-134 ydeI - - S - - - Bacteriocin-protection, YdeI or OmpD-Associated
NIIKMLNH_02723 4.13e-148 - - - - - - - -
NIIKMLNH_02724 5.21e-194 ydeK - - EG - - - -transporter
NIIKMLNH_02725 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NIIKMLNH_02726 2.49e-95 ydeM1 - - I - - - N-terminal half of MaoC dehydratase
NIIKMLNH_02727 2.81e-134 - - - S ko:K07002 - ko00000 Serine hydrolase
NIIKMLNH_02728 8.68e-74 - - - K - - - HxlR-like helix-turn-helix
NIIKMLNH_02729 6.56e-194 ydeO - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
NIIKMLNH_02730 8.61e-75 arsR - - K ko:K03892,ko:K22043 - ko00000,ko03000 transcriptional
NIIKMLNH_02731 3.38e-292 arsB - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NIIKMLNH_02732 1.51e-95 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Catalyzes the reduction of arsenate As(V) to arsenite As(III)
NIIKMLNH_02733 1.1e-184 - - - J - - - GNAT acetyltransferase
NIIKMLNH_02734 4.38e-146 - - - K - - - Transcriptional regulator
NIIKMLNH_02735 1.45e-157 nodB1 - - G - - - deacetylase
NIIKMLNH_02736 2.52e-199 - - - - - - - -
NIIKMLNH_02737 7.61e-279 - - - T - - - GHKL domain
NIIKMLNH_02738 3.89e-157 - - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
NIIKMLNH_02739 4.85e-191 - - - EG - - - EamA-like transporter family
NIIKMLNH_02740 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NIIKMLNH_02741 1.54e-232 - 4.1.1.86 - E ko:K13745 ko00260,ko01120,map00260,map01120 ko00000,ko00001,ko01000 Pyridoxal-dependent decarboxylase conserved domain
NIIKMLNH_02742 9.91e-150 ydfE - - S - - - Flavin reductase like domain
NIIKMLNH_02743 1.5e-158 ydfF - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
NIIKMLNH_02744 3.92e-104 - - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NIIKMLNH_02746 9.66e-252 ydfH 2.7.13.3 - T ko:K11623 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NIIKMLNH_02747 3.27e-142 ydfI - - K ko:K11624 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NIIKMLNH_02748 0.0 ydfJ - - S ko:K06994,ko:K11625 ko02020,map02020 ko00000,ko00001 drug exporters of the RND superfamily
NIIKMLNH_02749 1.31e-149 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
NIIKMLNH_02750 8.33e-187 - - - K - - - Bacterial transcription activator, effector binding domain
NIIKMLNH_02751 5e-197 ydfM - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NIIKMLNH_02752 1.51e-139 ydfN - - C ko:K15976 - ko00000,ko01000 nitroreductase
NIIKMLNH_02753 1.29e-236 ydfO - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
NIIKMLNH_02754 8.02e-84 ydfP - - S ko:K15977 - ko00000 DoxX
NIIKMLNH_02755 3.11e-73 ydfQ - - CO - - - Thioredoxin
NIIKMLNH_02756 2.4e-21 ydgA - - S - - - Spore germination protein gerPA/gerPF
NIIKMLNH_02757 3.22e-40 - - - - - - - -
NIIKMLNH_02759 9.11e-65 ydfR - - S - - - Protein of unknown function (DUF421)
NIIKMLNH_02760 9.94e-40 ydfR - - S - - - Protein of unknown function (DUF421)
NIIKMLNH_02761 8.96e-160 ydfS - - S - - - Protein of unknown function (DUF421)
NIIKMLNH_02762 2.57e-89 cotP - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
NIIKMLNH_02763 1.53e-47 ydgA - - S - - - Spore germination protein gerPA/gerPF
NIIKMLNH_02764 8.97e-47 ydgB - - S - - - Spore germination protein gerPA/gerPF
NIIKMLNH_02765 4.92e-127 ydgC - - K - - - Bacterial regulatory proteins, tetR family
NIIKMLNH_02766 6.73e-69 - - - S - - - DoxX-like family
NIIKMLNH_02767 3.51e-104 yycN - - K - - - Acetyltransferase
NIIKMLNH_02768 0.0 expZ - - S ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ABC transporter
NIIKMLNH_02769 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
NIIKMLNH_02770 1.4e-116 - - - S - - - DinB family
NIIKMLNH_02771 8.12e-104 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
NIIKMLNH_02772 0.0 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
NIIKMLNH_02773 6.42e-147 ydgI - - C - - - nitroreductase
NIIKMLNH_02774 3.29e-90 - - - K - - - Winged helix DNA-binding domain
NIIKMLNH_02775 9.46e-264 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
NIIKMLNH_02776 2.51e-155 ydhB - - S ko:K07090 - ko00000 membrane transporter protein
NIIKMLNH_02777 7.45e-158 ydhC - - K - - - FCD
NIIKMLNH_02778 2.1e-308 ydhD - - M - - - Glycosyl hydrolase
NIIKMLNH_02779 9.61e-290 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
NIIKMLNH_02780 6.08e-163 - - - - - - - -
NIIKMLNH_02781 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
NIIKMLNH_02782 2.26e-87 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
NIIKMLNH_02784 1.04e-105 - - - K - - - Acetyltransferase (GNAT) domain
NIIKMLNH_02785 6.35e-230 ydhJ - - S ko:K06885 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
NIIKMLNH_02786 2.59e-126 ydhK - - M - - - Protein of unknown function (DUF1541)
NIIKMLNH_02787 6.3e-255 ydhL - - EGP ko:K18567 - ko00000,ko02000 COG2814 Arabinose efflux permease
NIIKMLNH_02788 1.88e-63 ydhM 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NIIKMLNH_02789 3.39e-67 ydhN3 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NIIKMLNH_02790 2.27e-305 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NIIKMLNH_02791 0.0 ydhP 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NIIKMLNH_02792 1.83e-169 ydhQ - - K ko:K03492 - ko00000,ko03000 UTRA
NIIKMLNH_02793 1.65e-212 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
NIIKMLNH_02794 8.45e-239 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
NIIKMLNH_02795 1.12e-269 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
NIIKMLNH_02796 4.02e-201 ydhU - - P ko:K07217 - ko00000 Catalase
NIIKMLNH_02799 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
NIIKMLNH_02802 3.38e-225 thiL 2.7.4.16 - H ko:K00946 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NIIKMLNH_02803 7.42e-112 ydiB - - S ko:K06925 - ko00000,ko03016 ATPase or kinase
NIIKMLNH_02804 3.14e-157 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214 Inactive homolog of metal-dependent proteases
NIIKMLNH_02805 1.41e-108 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
NIIKMLNH_02806 7.76e-240 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NIIKMLNH_02807 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter
NIIKMLNH_02808 1.46e-117 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
NIIKMLNH_02809 2.14e-148 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NIIKMLNH_02810 5.48e-31 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
NIIKMLNH_02811 3.55e-161 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NIIKMLNH_02812 3.2e-37 ydiK - - S - - - Domain of unknown function (DUF4305)
NIIKMLNH_02813 4.09e-165 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
NIIKMLNH_02814 2.14e-58 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NIIKMLNH_02815 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NIIKMLNH_02816 5.85e-95 - - - L - - - Phage integrase family
NIIKMLNH_02817 4.63e-57 - - - L - - - Belongs to the 'phage' integrase family
NIIKMLNH_02819 1.31e-98 yddG - - S - - - maturation of SSU-rRNA
NIIKMLNH_02820 4.69e-26 yddG - - S - - - maturation of SSU-rRNA
NIIKMLNH_02821 5.47e-30 - - - S - - - branched-chain amino acid
NIIKMLNH_02822 1.85e-93 - - - E - - - AzlC protein
NIIKMLNH_02823 6.85e-201 gntR9 - - K - - - COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NIIKMLNH_02824 2.48e-18 - - - S - - - B3/4 domain
NIIKMLNH_02825 2.71e-163 megL 4.4.1.11 - E ko:K01761 ko00270,ko00450,map00270,map00450 ko00000,ko00001,ko01000 methionine gamma-lyase
NIIKMLNH_02826 5.11e-39 megL 4.4.1.11 - E ko:K01761 ko00270,ko00450,map00270,map00450 ko00000,ko00001,ko01000 methionine gamma-lyase
NIIKMLNH_02827 3.29e-158 - - - I - - - Fatty acid desaturase
NIIKMLNH_02828 3.41e-18 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
NIIKMLNH_02829 2.57e-191 ydjC - - S - - - Abhydrolase domain containing 18
NIIKMLNH_02830 0.0 gutR - - K ko:K16247 - ko00000,ko03000 NB-ARC domain
NIIKMLNH_02831 4.32e-258 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
NIIKMLNH_02832 0.0 gutP - - G ko:K03292,ko:K16248 - ko00000,ko02000 MFS/sugar transport protein
NIIKMLNH_02833 5.78e-219 ydjE 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
NIIKMLNH_02834 1.08e-147 pspA - - KT ko:K03969 - ko00000 Phage shock protein A
NIIKMLNH_02835 7.04e-226 ydjG - - L - - - Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NIIKMLNH_02836 4.37e-165 ydjH - - S ko:K06872 - ko00000 COG1512 Beta-propeller domains of methanol dehydrogenase type
NIIKMLNH_02837 3.61e-203 ydjI - - S - - - virion core protein (lumpy skin disease virus)
NIIKMLNH_02838 1.95e-248 - - - S - - - Ion transport 2 domain protein
NIIKMLNH_02839 0.0 iolT - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NIIKMLNH_02840 3.5e-249 ydjL 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
NIIKMLNH_02841 1.79e-84 ydjM - - M - - - Lytic transglycolase
NIIKMLNH_02842 1.14e-207 ydjN - - U - - - Involved in the tonB-independent uptake of proteins
NIIKMLNH_02844 9.99e-48 ydjO - - S - - - Cold-inducible protein YdjO
NIIKMLNH_02845 1.78e-202 - - - I - - - Alpha/beta hydrolase family
NIIKMLNH_02846 8.92e-225 yeaA - - S - - - Protein of unknown function (DUF4003)
NIIKMLNH_02847 0.0 cotA 1.16.3.3 - Q ko:K06324 - ko00000,ko01000 multicopper oxidases
NIIKMLNH_02848 0.0 gabP - - E ko:K11735 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
NIIKMLNH_02849 2.05e-197 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NIIKMLNH_02850 5.62e-226 yeaC - - S ko:K03924 - ko00000,ko01000 COG0714 MoxR-like ATPases
NIIKMLNH_02851 2.74e-286 yeaD - - S - - - conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
NIIKMLNH_02852 0.0 yebA - - E - - - COG1305 Transglutaminase-like enzymes
NIIKMLNH_02853 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
NIIKMLNH_02854 1.05e-109 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NIIKMLNH_02855 0.0 - - - S - - - Domain of unknown function (DUF4179)
NIIKMLNH_02856 9.81e-283 pbuG - - S ko:K06901 - ko00000,ko02000 permease
NIIKMLNH_02857 5.85e-165 yebC - - M - - - Membrane
NIIKMLNH_02859 2.66e-120 yebE - - S - - - UPF0316 protein
NIIKMLNH_02860 3.13e-38 yebG - - S - - - NETI protein
NIIKMLNH_02861 1.08e-106 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NIIKMLNH_02862 2.21e-276 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NIIKMLNH_02863 6.85e-315 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NIIKMLNH_02864 2.78e-166 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
NIIKMLNH_02865 3.79e-52 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NIIKMLNH_02866 1.91e-166 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NIIKMLNH_02867 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NIIKMLNH_02868 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NIIKMLNH_02869 9.88e-240 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
NIIKMLNH_02870 3.62e-137 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NIIKMLNH_02871 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
NIIKMLNH_02872 1.63e-297 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
NIIKMLNH_02873 1.06e-95 - - - K - - - helix_turn_helix ASNC type
NIIKMLNH_02874 5.84e-292 - - - E ko:K16263 - ko00000,ko02000 Amino acid permease
NIIKMLNH_02875 3.45e-37 - - - S - - - Protein of unknown function (DUF2892)
NIIKMLNH_02876 0.0 yerA 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 adenine deaminase
NIIKMLNH_02877 2.35e-244 yerB - - S - - - Protein of unknown function (DUF3048) C-terminal domain
NIIKMLNH_02878 7.62e-68 yerC - - S - - - protein conserved in bacteria
NIIKMLNH_02879 0.0 yerD 1.4.7.1 - E ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 ko00000,ko00001,ko01000 Belongs to the glutamate synthase family
NIIKMLNH_02881 1.1e-161 pcrB - - I ko:K07094 - ko00000,ko01000 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
NIIKMLNH_02882 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
NIIKMLNH_02883 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NIIKMLNH_02884 4.05e-265 camS - - S - - - COG4851 Protein involved in sex pheromone biosynthesis
NIIKMLNH_02886 6.75e-248 yerI - - S - - - homoserine kinase type II (protein kinase fold)
NIIKMLNH_02887 2.29e-160 sapB - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
NIIKMLNH_02888 0.0 putP - - E ko:K03307,ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NIIKMLNH_02889 7.37e-61 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NIIKMLNH_02890 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NIIKMLNH_02891 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NIIKMLNH_02892 7.45e-184 yerO - - K - - - Transcriptional regulator
NIIKMLNH_02893 0.0 swrC - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NIIKMLNH_02894 1.8e-218 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NIIKMLNH_02895 0.0 rlmCD 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NIIKMLNH_02896 1.14e-27 - - - - - - - -
NIIKMLNH_02897 0.0 - - - K - - - SIR2-like domain
NIIKMLNH_02899 5.6e-125 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
NIIKMLNH_02900 1.15e-05 - - - - - - - -
NIIKMLNH_02901 4.69e-39 - - - S - - - Colicin immunity protein / pyocin immunity protein
NIIKMLNH_02903 8.88e-102 - - - S - - - Protein of unknown function, DUF600
NIIKMLNH_02904 1.56e-78 - - - S - - - Protein of unknown function, DUF600
NIIKMLNH_02905 0.0 - - - L - - - nucleic acid phosphodiester bond hydrolysis
NIIKMLNH_02907 1.4e-126 - - - L - - - endonuclease activity
NIIKMLNH_02908 7.9e-212 - 3.4.24.40 - CO ko:K01406 ko01503,map01503 ko00000,ko00001,ko01000,ko01002 amine dehydrogenase activity
NIIKMLNH_02909 3.56e-15 - - - S - - - Pfam:DUF1311
NIIKMLNH_02910 2.26e-267 rapH - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Tetratricopeptide repeat
NIIKMLNH_02912 6.29e-162 yeeN - - K - - - transcriptional regulatory protein
NIIKMLNH_02914 1.16e-128 dhaR3 - - K ko:K16137 - ko00000,ko03000 Transcriptional regulator
NIIKMLNH_02915 1.6e-103 yesE - - S ko:K06893 - ko00000 SnoaL-like domain
NIIKMLNH_02916 1.23e-195 yesF - - GM - - - NAD(P)H-binding
NIIKMLNH_02917 3.8e-60 cotJA - - S ko:K06332 - ko00000 Spore coat associated protein JA (CotJA)
NIIKMLNH_02918 2.31e-61 cotJB - - S ko:K06333 - ko00000 CotJB protein
NIIKMLNH_02919 3e-133 cotJC - - P ko:K06334 - ko00000 Spore Coat
NIIKMLNH_02920 2.8e-129 yesJ - - K - - - Acetyltransferase (GNAT) family
NIIKMLNH_02922 1.95e-132 yesL - - S - - - Protein of unknown function, DUF624
NIIKMLNH_02923 0.0 yesM 2.7.13.3 - T ko:K07718 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NIIKMLNH_02924 1.81e-253 - - - K ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, arabinose operon control protein
NIIKMLNH_02925 1.61e-311 yesO - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
NIIKMLNH_02926 5.79e-218 yesP - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NIIKMLNH_02927 5.33e-212 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NIIKMLNH_02928 9.34e-253 - 3.2.1.172 GH105 S ko:K15532 - ko00000,ko01000 Glycosyl Hydrolase Family 88
NIIKMLNH_02929 0.0 yesS - - K - - - Transcriptional regulator
NIIKMLNH_02930 1.63e-167 - - - E - - - GDSL-like Lipase/Acylhydrolase
NIIKMLNH_02931 2.13e-74 yesU - - S - - - Domain of unknown function (DUF1961)
NIIKMLNH_02932 1.64e-144 - - - S - - - Protein of unknown function, DUF624
NIIKMLNH_02933 0.0 - 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
NIIKMLNH_02934 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
NIIKMLNH_02936 3.72e-159 - - - E - - - GDSL-like Lipase/Acylhydrolase
NIIKMLNH_02937 0.0 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase activity
NIIKMLNH_02938 0.0 yetA - - - - - - -
NIIKMLNH_02939 0.0 lplA - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
NIIKMLNH_02940 3.25e-224 lplB - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
NIIKMLNH_02941 7.85e-209 - - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NIIKMLNH_02942 0.0 - 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
NIIKMLNH_02943 1.81e-157 yetF - - S - - - membrane
NIIKMLNH_02944 5.46e-72 yetG 1.14.99.48 - S ko:K07145 ko00860,ko01110,map00860,map01110 ko00000,ko00001,ko01000 Antibiotic biosynthesis monooxygenase
NIIKMLNH_02945 2.47e-85 yetH - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NIIKMLNH_02946 1.75e-44 - - - - - - - -
NIIKMLNH_02947 4.37e-185 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NIIKMLNH_02948 3.81e-28 yezD - - S - - - Uncharacterized small protein (DUF2292)
NIIKMLNH_02949 5.15e-135 yetJ - - S ko:K06890 - ko00000 Belongs to the BI1 family
NIIKMLNH_02950 2.04e-08 - - - EG - - - EamA-like transporter family
NIIKMLNH_02951 1.86e-114 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
NIIKMLNH_02952 1.26e-265 yetM - - CH - - - FAD binding domain
NIIKMLNH_02953 9.87e-173 - - - M - - - Membrane
NIIKMLNH_02954 4.11e-251 yetN - - S - - - Protein of unknown function (DUF3900)
NIIKMLNH_02955 0.0 cypD 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
NIIKMLNH_02956 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
NIIKMLNH_02957 9.83e-187 yfnH 2.7.7.33 - JM ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 ko00000,ko00001,ko01000 Nucleotidyl transferase
NIIKMLNH_02958 1.37e-219 yfnG 4.2.1.45, 4.2.1.46 - M ko:K01709,ko:K01710 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 dehydratase
NIIKMLNH_02959 5.22e-227 yfnF - - M - - - Nucleotide-diphospho-sugar transferase
NIIKMLNH_02960 2.44e-286 yfnE - - S - - - Glycosyltransferase like family 2
NIIKMLNH_02961 3.88e-242 yfnD - - M - - - Nucleotide-diphospho-sugar transferase
NIIKMLNH_02962 4.18e-266 fsr - - P ko:K08223 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
NIIKMLNH_02963 1.38e-163 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
NIIKMLNH_02964 2.4e-312 yfnA - - E ko:K03294 - ko00000 amino acid
NIIKMLNH_02965 0.0 yfmT 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NIIKMLNH_02966 5.14e-161 yfmS - - NT - - - chemotaxis protein
NIIKMLNH_02967 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NIIKMLNH_02968 3.61e-96 yfmQ - - S - - - Uncharacterised protein from bacillus cereus group
NIIKMLNH_02969 3.54e-90 yfmP - - K ko:K21902 - ko00000,ko03000 transcriptional
NIIKMLNH_02970 2.42e-263 yfmO - - EGP ko:K08221 - ko00000,ko02000 Major facilitator superfamily
NIIKMLNH_02971 2.88e-46 - - - O - - - Subtilase family
NIIKMLNH_02972 9.1e-23 - - - - - - - -
NIIKMLNH_02974 3.95e-74 - - - - - - - -
NIIKMLNH_02975 0.0 yheS_1 - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NIIKMLNH_02976 1.71e-262 yfmL - - L - - - COG0513 Superfamily II DNA and RNA helicases
NIIKMLNH_02977 1.86e-98 yfmK 2.3.1.128 - K ko:K03790 - ko00000,ko01000,ko03009 acetyltransferase
NIIKMLNH_02978 2.84e-240 yfmJ - - S ko:K07119 - ko00000 N-terminal domain of oxidoreductase
NIIKMLNH_02979 1.4e-192 fhuC 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
NIIKMLNH_02980 2.98e-223 fecD - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NIIKMLNH_02981 8.17e-221 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NIIKMLNH_02982 1.17e-220 yfmC - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
NIIKMLNH_02983 1.06e-31 - - - S - - - Protein of unknown function (DUF3212)
NIIKMLNH_02984 1.71e-76 yflT - - S - - - Heat induced stress protein YflT
NIIKMLNH_02985 2.01e-306 pel 4.2.2.2 - G ko:K01728 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
NIIKMLNH_02986 0.0 yflS - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
NIIKMLNH_02987 0.0 citS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
NIIKMLNH_02988 1.33e-152 citT - - T ko:K11638 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
NIIKMLNH_02989 3.98e-230 yflP - - S - - - Tripartite tricarboxylate transporter family receptor
NIIKMLNH_02990 5.35e-288 citM - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
NIIKMLNH_02991 1.7e-192 yflN - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
NIIKMLNH_02992 3.24e-274 nos 1.14.14.47 - C ko:K00491 ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the NOS family. Bacterial NOS oxygenase subfamily
NIIKMLNH_02993 2.97e-59 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
NIIKMLNH_02994 3.42e-157 yflK - - S - - - protein conserved in bacteria
NIIKMLNH_02995 1.29e-24 yflJ - - S - - - Protein of unknown function (DUF2639)
NIIKMLNH_02996 6.9e-27 yflI - - - - - - -
NIIKMLNH_02997 3.63e-66 yflH - - S - - - Protein of unknown function (DUF3243)
NIIKMLNH_02998 1.14e-178 yflG 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
NIIKMLNH_02999 0.0 nagE 2.7.1.193, 2.7.1.199 - G ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
NIIKMLNH_03000 0.0 yflE 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
NIIKMLNH_03001 2.2e-86 ydhN1 - - S - - - Domain of unknown function (DUF1992)
NIIKMLNH_03002 0.0 yflA - - E ko:K03310 - ko00000 Sodium alanine symporter
NIIKMLNH_03003 2.1e-247 yfkT - - E ko:K06309 - ko00000 Spore germination protein
NIIKMLNH_03005 2.66e-270 yfkR - - S ko:K06297,ko:K06308 - ko00000 spore germination
NIIKMLNH_03006 0.0 yfkQ - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
NIIKMLNH_03007 0.0 treP 2.7.1.201 - G ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NIIKMLNH_03008 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
NIIKMLNH_03009 1.24e-172 treR - - K ko:K03486 - ko00000,ko03000 transcriptional
NIIKMLNH_03010 6.16e-160 frp - - C - - - nitroreductase
NIIKMLNH_03011 0.0 yfkN 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K01119,ko:K06931,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
NIIKMLNH_03012 3.17e-113 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
NIIKMLNH_03013 1.46e-264 ydiN3 - - EGP - - - COG0477 Permeases of the major facilitator superfamily
NIIKMLNH_03014 5.99e-41 yfkK - - S - - - Belongs to the UPF0435 family
NIIKMLNH_03015 8.37e-108 yfkJ 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NIIKMLNH_03016 2.08e-66 yfkI - - S - - - gas vesicle protein
NIIKMLNH_03017 9.64e-184 yihY - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
NIIKMLNH_03018 1.64e-12 - - - - - - - -
NIIKMLNH_03019 1.9e-278 yfkF - - EGP - - - COG0477 Permeases of the major facilitator superfamily
NIIKMLNH_03020 1.34e-235 cax - - P ko:K07300 - ko00000,ko02000 COG0387 Ca2 H antiporter
NIIKMLNH_03021 3.69e-189 yfkD - - S - - - YfkD-like protein
NIIKMLNH_03022 4.44e-191 yfkC - - M - - - Mechanosensitive ion channel
NIIKMLNH_03023 1.76e-283 yfkA - - S - - - YfkB-like domain
NIIKMLNH_03024 3.26e-36 yfjT - - - - - - -
NIIKMLNH_03025 7.24e-198 pdaA - - G ko:K01567 - ko00000,ko01000 deacetylase
NIIKMLNH_03026 3.63e-189 yfjR - - I - - - NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
NIIKMLNH_03027 3.18e-236 corA - - P ko:K03284 - ko00000,ko02000 Mediates influx of magnesium ions
NIIKMLNH_03028 9.24e-213 yfjP 3.2.2.21 - L ko:K01247 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NIIKMLNH_03029 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NIIKMLNH_03030 3.31e-57 - - - S - - - YfzA-like protein
NIIKMLNH_03031 2.83e-51 yfjN - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NIIKMLNH_03032 2.5e-170 yfjN - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NIIKMLNH_03033 3.74e-108 yfjM - - S - - - Psort location Cytoplasmic, score
NIIKMLNH_03034 1.36e-244 acoA - - C ko:K21416 - ko00000,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NIIKMLNH_03035 1.59e-243 acoB - - C ko:K21417 - ko00000,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NIIKMLNH_03036 1.82e-259 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NIIKMLNH_03037 0.0 acoL 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NIIKMLNH_03038 0.0 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
NIIKMLNH_03039 8.16e-36 sspH - - S ko:K06425 - ko00000 Belongs to the SspH family
NIIKMLNH_03040 7.42e-75 yfjF - - S ko:K09771 - ko00000,ko02000 UPF0060 membrane protein
NIIKMLNH_03041 2.16e-100 - - - S - - - Family of unknown function (DUF5381)
NIIKMLNH_03042 1.49e-131 yfjD - - S - - - Family of unknown function (DUF5381)
NIIKMLNH_03043 2.5e-185 yfjC - - - - - - -
NIIKMLNH_03044 5.56e-270 yfjB - - - - - - -
NIIKMLNH_03045 5.59e-61 yfjA - - S - - - Belongs to the WXG100 family
NIIKMLNH_03048 9.67e-25 - - - S - - - protein conserved in bacteria
NIIKMLNH_03050 1.77e-88 - - - S - - - LXG domain of WXG superfamily
NIIKMLNH_03053 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
NIIKMLNH_03054 5.03e-180 - - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
NIIKMLNH_03055 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NIIKMLNH_03056 0.0 yfiB3 - - V ko:K06147 - ko00000,ko02000 ABC transporter
NIIKMLNH_03057 0.0 yfiC3 - - V ko:K06147 - ko00000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
NIIKMLNH_03058 2.01e-84 yfiD3 - - S - - - DoxX
NIIKMLNH_03059 2.85e-206 yfiE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
NIIKMLNH_03060 3.4e-239 baeS - - T - - - Histidine kinase
NIIKMLNH_03061 8.27e-144 yfiK - - KT ko:K02479 - ko00000,ko02022 LuxR family transcriptional regulator
NIIKMLNH_03062 3.75e-215 drrA - - V ko:K01990,ko:K09695 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NIIKMLNH_03063 6.49e-268 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
NIIKMLNH_03064 6.93e-262 - - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
NIIKMLNH_03065 1.89e-128 padR - - K - - - transcriptional
NIIKMLNH_03066 7.87e-128 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
NIIKMLNH_03067 2.68e-252 yfiQ - - G ko:K21462 - ko00000 COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
NIIKMLNH_03068 1.56e-125 yfiT - - S - - - Belongs to the metal hydrolase YfiT family
NIIKMLNH_03069 0.0 yfiU - - EGP - - - the major facilitator superfamily
NIIKMLNH_03070 2.11e-103 yfiV - - K - - - transcriptional
NIIKMLNH_03071 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NIIKMLNH_03072 6.35e-230 yfiY - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
NIIKMLNH_03073 8.91e-225 yfiZ - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NIIKMLNH_03074 7.36e-229 yfhA - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NIIKMLNH_03075 1.72e-211 yfhB - - S - - - PhzF family
NIIKMLNH_03076 2.87e-138 yfhC - - C - - - nitroreductase
NIIKMLNH_03077 8.86e-35 yfhD - - S - - - YfhD-like protein
NIIKMLNH_03079 1.54e-219 yfhF - - S ko:K07071 - ko00000 nucleoside-diphosphate sugar epimerase
NIIKMLNH_03080 1.88e-180 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
NIIKMLNH_03081 4.58e-69 yfhH - - S - - - Protein of unknown function (DUF1811)
NIIKMLNH_03083 4.94e-268 yfhI - - EGP - - - -transporter
NIIKMLNH_03084 2.25e-27 sspK - - S ko:K06428 - ko00000 reproduction
NIIKMLNH_03085 8.95e-60 yfhJ - - S - - - WVELL protein
NIIKMLNH_03086 1.91e-114 yfhK - - T - - - Bacterial SH3 domain homologues
NIIKMLNH_03087 6.3e-66 yfhL - - S - - - SdpI/YhfL protein family
NIIKMLNH_03088 6.53e-217 yfhM 3.8.1.5 - S ko:K01563 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Alpha beta hydrolase
NIIKMLNH_03089 3.43e-236 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
NIIKMLNH_03090 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
NIIKMLNH_03091 2.07e-236 yfhP - - S ko:K07038 - ko00000 membrane-bound metal-dependent
NIIKMLNH_03092 1.31e-265 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific
NIIKMLNH_03093 1.73e-48 yfhS - - - - - - -
NIIKMLNH_03094 3.13e-172 fabL 1.3.1.104 - IQ ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NIIKMLNH_03095 2.35e-14 sspE - - S ko:K06422 - ko00000 Small, acid-soluble spore protein, gamma-type
NIIKMLNH_03096 4.06e-49 ygaB - - S - - - YgaB-like protein
NIIKMLNH_03097 2.32e-135 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
NIIKMLNH_03098 0.0 ygaD - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
NIIKMLNH_03099 1.87e-238 ygaE - - S - - - Membrane
NIIKMLNH_03100 3.26e-312 gsaB 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
NIIKMLNH_03101 2.92e-113 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Peroxiredoxin
NIIKMLNH_03102 2.37e-104 perR - - P ko:K09825 - ko00000,ko03000 Belongs to the Fur family
NIIKMLNH_03103 3.38e-73 ygzB - - S - - - UPF0295 protein
NIIKMLNH_03104 2.36e-214 ygxA - - S - - - Nucleotidyltransferase-like
NIIKMLNH_03105 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
NIIKMLNH_03122 2.17e-65 - - - - - - - -
NIIKMLNH_03124 3.54e-77 - - - L ko:K07451,ko:K07453 - ko00000,ko01000,ko02048 HNH endonuclease
NIIKMLNH_03125 4.15e-65 - - - V ko:K07451 - ko00000,ko01000,ko02048 endonuclease activity
NIIKMLNH_03126 5.03e-182 spo0M - - S ko:K06377 - ko00000 COG4326 Sporulation control protein
NIIKMLNH_03127 1.58e-36 - - - - - - - -
NIIKMLNH_03128 2.93e-167 ygaJ 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
NIIKMLNH_03129 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NIIKMLNH_03131 0.0 katA 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
NIIKMLNH_03132 2.58e-178 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
NIIKMLNH_03133 6.93e-217 ssuA - - M ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Sulfonate ABC transporter
NIIKMLNH_03134 1.68e-189 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
NIIKMLNH_03135 5.41e-275 ssuD 1.14.14.28, 1.14.14.5 - C ko:K04091,ko:K20938 ko00920,map00920 ko00000,ko00001,ko01000 Catalyzes the desulfonation of aliphatic sulfonates
NIIKMLNH_03137 4.82e-55 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NIIKMLNH_03138 5.19e-98 ygaO - - - - - - -
NIIKMLNH_03139 1.48e-39 - - - K ko:K07729 - ko00000,ko03000 Transcriptional regulator
NIIKMLNH_03141 7.51e-145 yhzB - - S - - - B3/4 domain
NIIKMLNH_03142 1.2e-283 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NIIKMLNH_03143 1.6e-224 yhbB - - S - - - Putative amidase domain
NIIKMLNH_03144 1.87e-112 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NIIKMLNH_03145 3.4e-143 yhbD - - K - - - Protein of unknown function (DUF4004)
NIIKMLNH_03146 1.32e-95 yhbE - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
NIIKMLNH_03147 2.46e-104 yhbF - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
NIIKMLNH_03148 0.0 prkA - - T ko:K07180 - ko00000 Ser protein kinase
NIIKMLNH_03149 1.21e-286 yhbH - - S ko:K09786 - ko00000 Belongs to the UPF0229 family
NIIKMLNH_03150 1.29e-101 yhbI - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
NIIKMLNH_03151 2.67e-133 yhbJ - - V - - - COG1566 Multidrug resistance efflux pump
NIIKMLNH_03152 0.0 yhcA - - EGP ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
NIIKMLNH_03153 4.87e-128 yhcB 1.6.5.2 - S ko:K03809 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 Belongs to the WrbA family
NIIKMLNH_03154 9.3e-58 yhcC - - - - - - -
NIIKMLNH_03156 2.06e-69 - - - - - - - -
NIIKMLNH_03157 1.67e-79 yhcF - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator
NIIKMLNH_03158 3.24e-156 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NIIKMLNH_03159 2.95e-209 yhcH - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NIIKMLNH_03160 1.15e-210 yhcI - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NIIKMLNH_03161 1.91e-42 cspB - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
NIIKMLNH_03162 9.06e-194 metQ_3 - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
NIIKMLNH_03163 2.76e-248 yhcK 2.7.7.65 - T ko:K18967 - ko00000,ko01000,ko02000 COG2199 FOG GGDEF domain
NIIKMLNH_03164 2.62e-301 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NIIKMLNH_03165 8.05e-113 - - - S - - - Protein of unknown function (DUF2812)
NIIKMLNH_03166 3.22e-65 - - - K - - - Transcriptional regulator PadR-like family
NIIKMLNH_03167 1.09e-61 yhcM - - - - - - -
NIIKMLNH_03168 9.32e-108 yhcN - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NIIKMLNH_03169 3.12e-224 yhcP - - - - - - -
NIIKMLNH_03170 2.39e-146 yhcQ - - M - - - Spore coat protein
NIIKMLNH_03171 0.0 yhcR 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01081,ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
NIIKMLNH_03172 1.78e-134 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
NIIKMLNH_03173 4.78e-218 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
NIIKMLNH_03174 4.27e-89 yhcU - - S - - - Family of unknown function (DUF5365)
NIIKMLNH_03175 1.76e-90 yhcV - - S - - - COG0517 FOG CBS domain
NIIKMLNH_03176 2.5e-154 yhcW - - S ko:K07025 - ko00000 hydrolase
NIIKMLNH_03177 0.0 yhcX - - K - - - Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
NIIKMLNH_03178 0.0 yhxA - - E - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NIIKMLNH_03179 6.25e-134 glpP - - K ko:K02443 - ko00000,ko03000 Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
NIIKMLNH_03180 4.68e-195 glpF - - G ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
NIIKMLNH_03181 0.0 glpK 2.7.1.30 - C ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NIIKMLNH_03182 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NIIKMLNH_03183 0.0 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
NIIKMLNH_03184 1.88e-272 yhcY 2.7.13.3 - T ko:K02480 - ko00000,ko01000,ko01001,ko02022 Histidine kinase
NIIKMLNH_03185 5.44e-144 yhcZ - - K ko:K02479 - ko00000,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NIIKMLNH_03186 6.64e-116 yhdA 1.7.1.6 - S ko:K03206 - ko00000,ko01000 NADPH-dependent FMN reductase
NIIKMLNH_03187 1.65e-51 yhdB - - S - - - YhdB-like protein
NIIKMLNH_03188 1.02e-71 yhdC - - S - - - Protein of unknown function (DUF3889)
NIIKMLNH_03189 2.29e-273 lytF - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
NIIKMLNH_03190 1.95e-99 nsrR - - K ko:K13771 ko05132,map05132 ko00000,ko00001,ko03000 Transcriptional regulator
NIIKMLNH_03191 1.44e-304 ygxB - - M - - - Conserved TM helix
NIIKMLNH_03192 0.0 spoVR - - S ko:K06415 - ko00000 Stage V sporulation protein R
NIIKMLNH_03193 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
NIIKMLNH_03194 1.45e-203 lytE - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
NIIKMLNH_03195 4.93e-210 citR - - K ko:K19242 - ko00000,ko03000 Transcriptional regulator
NIIKMLNH_03196 1.06e-260 citA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
NIIKMLNH_03197 1.58e-205 yhdF - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NIIKMLNH_03198 3.58e-316 yhdG - - E ko:K03294 - ko00000 amino acid
NIIKMLNH_03199 1.01e-308 yhdH - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
NIIKMLNH_03200 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NIIKMLNH_03201 1.75e-100 - - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NIIKMLNH_03202 4.27e-59 yhdK - - S - - - Sigma-M inhibitor protein
NIIKMLNH_03203 1.02e-256 yhdL - - S - - - Sigma factor regulator N-terminal
NIIKMLNH_03204 3.24e-113 sigM - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NIIKMLNH_03205 6.74e-244 yhdN - - C - - - Aldo keto reductase
NIIKMLNH_03206 3.9e-143 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
NIIKMLNH_03207 2.18e-304 yhdP - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
NIIKMLNH_03208 3.44e-97 cueR - - K ko:K11923 - ko00000,ko03000 transcriptional
NIIKMLNH_03209 5.1e-284 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
NIIKMLNH_03210 0.0 yhdT - - P - - - COG1253 Hemolysins and related proteins containing CBS domains
NIIKMLNH_03211 2.48e-66 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NIIKMLNH_03212 1.67e-86 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NIIKMLNH_03213 9.03e-173 yhdW 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
NIIKMLNH_03214 3.7e-09 yhdX - - S - - - Uncharacterized protein YhdX
NIIKMLNH_03215 9.73e-239 yhdY - - M ko:K16052 - ko00000,ko02000 Mechanosensitive ion channel
NIIKMLNH_03216 3.99e-178 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
NIIKMLNH_03217 3.54e-194 nodB1 - - G - - - deacetylase
NIIKMLNH_03218 3.16e-197 dat 2.6.1.21 - E ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
NIIKMLNH_03219 8.48e-302 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter
NIIKMLNH_03220 1.53e-108 nhaX - - T - - - Belongs to the universal stress protein A family
NIIKMLNH_03221 0.0 yheI - - V ko:K18216,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
NIIKMLNH_03222 0.0 yheH - - V ko:K06147,ko:K18217,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
NIIKMLNH_03223 3.18e-141 yheG - - GM - - - NAD(P)H-binding
NIIKMLNH_03224 1.25e-38 sspB - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
NIIKMLNH_03225 2.27e-49 yheE - - S - - - Family of unknown function (DUF5342)
NIIKMLNH_03226 0.0 yheD - - HJ - - - YheC/D like ATP-grasp
NIIKMLNH_03227 1.32e-273 yheC - - HJ - - - YheC/D like ATP-grasp
NIIKMLNH_03228 4.16e-259 yheB - - S - - - Belongs to the UPF0754 family
NIIKMLNH_03229 7.46e-72 yheA - - S - - - Belongs to the UPF0342 family
NIIKMLNH_03230 1.58e-262 yhaZ - - L - - - DNA alkylation repair enzyme
NIIKMLNH_03231 8.7e-198 yhaX - - S - - - haloacid dehalogenase-like hydrolase
NIIKMLNH_03232 0.0 hemZ - - H - - - coproporphyrinogen III oxidase
NIIKMLNH_03233 1.52e-266 yhaU - - P ko:K03455 - ko00000 COG0475 Kef-type K transport systems, membrane components
NIIKMLNH_03234 6.51e-114 - - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
NIIKMLNH_03236 1.79e-169 yhaR - - I - - - enoyl-CoA hydratase
NIIKMLNH_03237 2.29e-36 - - - S - - - YhzD-like protein
NIIKMLNH_03238 1.86e-213 yhaQ - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NIIKMLNH_03239 5.14e-272 yhaP - - CP ko:K01992 - ko00000,ko00002,ko02000 COG1668 ABC-type Na efflux pump, permease component
NIIKMLNH_03240 9.44e-301 yhaO - - L ko:K03547 - ko00000,ko03400 DNA repair exonuclease
NIIKMLNH_03241 0.0 yhaN - - L - - - AAA domain
NIIKMLNH_03242 2.13e-227 yhaM - - L ko:K03698 - ko00000,ko01000,ko03019 Shows a 3'-5' exoribonuclease activity
NIIKMLNH_03243 1.88e-39 yhaL - - S - - - Sporulation protein YhaL
NIIKMLNH_03244 8.42e-161 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NIIKMLNH_03245 1.4e-116 yhaK - - S - - - Putative zincin peptidase
NIIKMLNH_03246 8.48e-73 yhaI - - S - - - Protein of unknown function (DUF1878)
NIIKMLNH_03247 4.92e-148 hpr - - K ko:K09682 - ko00000,ko03000 Negative regulator of protease production and sporulation
NIIKMLNH_03248 3.89e-54 yhaH - - S - - - YtxH-like protein
NIIKMLNH_03249 9.66e-30 - - - - - - - -
NIIKMLNH_03250 1.28e-103 trpP - - S - - - Tryptophan transporter TrpP
NIIKMLNH_03251 2.51e-260 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NIIKMLNH_03252 3.5e-106 hit - - FG ko:K02503 - ko00000,ko04147 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
NIIKMLNH_03253 6.35e-175 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 transporter (ATP-binding protein)
NIIKMLNH_03254 3.11e-272 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
NIIKMLNH_03255 8.29e-161 ecsC - - S - - - EcsC protein family
NIIKMLNH_03256 5.37e-292 yhaA - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
NIIKMLNH_03257 3.27e-311 yhfA - - C - - - membrane
NIIKMLNH_03258 1e-44 - - - C - - - Rubrerythrin
NIIKMLNH_03259 1.31e-118 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
NIIKMLNH_03260 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
NIIKMLNH_03261 1.24e-257 hemE 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NIIKMLNH_03262 3.99e-230 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
NIIKMLNH_03263 0.0 hemY 1.3.3.15, 1.3.3.4 - H ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
NIIKMLNH_03264 1e-132 yhgD - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
NIIKMLNH_03265 0.0 yhgE - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
NIIKMLNH_03266 3.57e-236 fabHB 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NIIKMLNH_03267 3.8e-177 yhfC - - S - - - Putative membrane peptidase family (DUF2324)
NIIKMLNH_03268 1.55e-252 yhfE - - G - - - peptidase M42
NIIKMLNH_03269 1.53e-93 - - - S - - - ASCH
NIIKMLNH_03270 4.77e-289 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NIIKMLNH_03271 8.42e-183 yhfI - - S - - - COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
NIIKMLNH_03272 4.06e-245 lplJ 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
NIIKMLNH_03273 8.31e-141 yhfK - - GM - - - NmrA-like family
NIIKMLNH_03274 0.0 yhfL 6.2.1.3 - IQ ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
NIIKMLNH_03275 2.28e-84 yhfM - - - - - - -
NIIKMLNH_03276 6.5e-306 yhfN - - O - - - Peptidase M48
NIIKMLNH_03277 6.91e-260 aprE 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
NIIKMLNH_03278 4.38e-102 - - - K - - - acetyltransferase
NIIKMLNH_03279 2.4e-232 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Quinone oxidoreductase
NIIKMLNH_03280 1.32e-221 yhfQ - - M ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
NIIKMLNH_03281 2.27e-139 yhfR 5.4.2.12 - G ko:K15634,ko:K15640 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
NIIKMLNH_03282 5.18e-251 yhfS 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
NIIKMLNH_03283 0.0 vraA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
NIIKMLNH_03284 1.47e-118 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
NIIKMLNH_03285 4.33e-259 hemAT - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
NIIKMLNH_03286 0.0 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
NIIKMLNH_03287 2.24e-203 yhxC - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NIIKMLNH_03288 9.84e-45 yhzC - - S - - - IDEAL
NIIKMLNH_03289 6.29e-141 comK - - K ko:K02250 ko02024,map02024 ko00000,ko00001,ko02044,ko03000 Competence transcription factor
NIIKMLNH_03290 2.55e-216 yhxD - - IQ - - - Enoyl-(Acyl carrier protein) reductase
NIIKMLNH_03291 1.38e-54 yhjA - - S - - - Excalibur calcium-binding domain
NIIKMLNH_03292 0.0 yhjB - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NIIKMLNH_03293 1.61e-36 yhjC - - S - - - Protein of unknown function (DUF3311)
NIIKMLNH_03294 8.34e-78 yhjD - - - - - - -
NIIKMLNH_03295 4.87e-141 yhjE - - S - - - SNARE associated Golgi protein
NIIKMLNH_03296 3.09e-118 spsB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
NIIKMLNH_03297 0.0 yhjG - - CH - - - FAD binding domain
NIIKMLNH_03298 6.39e-119 yhjH - - K - - - helix_turn_helix multiple antibiotic resistance protein
NIIKMLNH_03301 2.11e-270 glcP - - G ko:K08174 - ko00000,ko02000 Major Facilitator Superfamily
NIIKMLNH_03302 6.61e-256 - 1.1.1.18, 1.1.1.361, 1.1.1.369 - S ko:K00010,ko:K18652 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
NIIKMLNH_03303 5.31e-205 ntdB 3.1.3.24, 3.1.3.92 - S ko:K07024,ko:K18654 ko00500,map00500 ko00000,ko00001,ko01000 Sucrose-6F-phosphate phosphohydrolase
NIIKMLNH_03304 0.0 - 2.6.1.104 - E ko:K18653 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
NIIKMLNH_03305 1.46e-237 yhjM - - K - - - Transcriptional regulator
NIIKMLNH_03306 2.05e-258 yhjN - - S ko:K07120 - ko00000 membrane
NIIKMLNH_03307 1.69e-261 - - - EGP - - - Transmembrane secretion effector
NIIKMLNH_03308 0.0 - - - S - - - Sugar transport-related sRNA regulator N-term
NIIKMLNH_03309 9.3e-102 yhjR - - S - - - Rubrerythrin
NIIKMLNH_03310 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 ATP-dependent helicase deoxyribonuclease subunit B
NIIKMLNH_03311 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
NIIKMLNH_03312 1.4e-280 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NIIKMLNH_03313 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 COG0419 ATPase involved in DNA repair
NIIKMLNH_03314 2.61e-64 yisB - - V - - - COG1403 Restriction endonuclease
NIIKMLNH_03315 3.3e-43 gerPF - - S ko:K06299,ko:K06304 - ko00000 Spore germination protein gerPA/gerPF
NIIKMLNH_03316 9.24e-85 gerPE - - S ko:K06303 - ko00000 Spore germination protein GerPE
NIIKMLNH_03317 6.07e-33 gerPD - - S ko:K06302 - ko00000 Spore germination protein
NIIKMLNH_03318 3.34e-92 gerPC - - S ko:K06301 - ko00000 Spore germination protein
NIIKMLNH_03319 3.87e-42 gerPB - - S ko:K06300 - ko00000 cell differentiation
NIIKMLNH_03320 1.82e-45 gerPA - - S ko:K06299 - ko00000 Spore germination protein
NIIKMLNH_03321 1.52e-32 yisI - - S - - - Spo0E like sporulation regulatory protein
NIIKMLNH_03322 1.09e-221 cotH - - M ko:K06330 - ko00000 Spore Coat
NIIKMLNH_03323 2.66e-219 yisK - - Q - - - COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
NIIKMLNH_03324 1.02e-74 yisL - - S - - - UPF0344 protein
NIIKMLNH_03325 0.0 wprA - - O ko:K13274 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
NIIKMLNH_03326 8.67e-131 yisN - - S - - - Protein of unknown function (DUF2777)
NIIKMLNH_03327 0.0 asnO 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
NIIKMLNH_03328 6.22e-114 yizA - - S - - - Damage-inducible protein DinB
NIIKMLNH_03329 5.37e-190 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 phytoene
NIIKMLNH_03330 2.91e-310 yisQ - - V - - - Mate efflux family protein
NIIKMLNH_03331 6.71e-206 yisR - - K - - - Transcriptional regulator
NIIKMLNH_03332 6.13e-234 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
NIIKMLNH_03333 4.25e-248 yisS 1.1.1.18, 1.1.1.369, 1.1.1.370 - S ko:K00010,ko:K16043 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
NIIKMLNH_03334 1.72e-120 yisT - - S - - - DinB family
NIIKMLNH_03335 1.05e-137 argO - - S ko:K06895 - ko00000,ko02000 Lysine exporter protein LysE YggA
NIIKMLNH_03336 3.77e-50 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NIIKMLNH_03337 2.42e-249 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NIIKMLNH_03338 1.76e-95 yisX - - S - - - Pentapeptide repeats (9 copies)
NIIKMLNH_03339 5.29e-198 yisY 1.11.1.10 - I ko:K00433 - ko00000,ko01000 hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NIIKMLNH_03340 4.06e-145 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
NIIKMLNH_03341 7.62e-293 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
NIIKMLNH_03342 1.58e-183 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
NIIKMLNH_03343 2.29e-154 - 3.1.3.71 - H ko:K05979 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the ComB family
NIIKMLNH_03344 7.15e-179 yitD 4.4.1.19 - S ko:K08097 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko00002,ko01000 synthase
NIIKMLNH_03345 6.77e-145 yitE - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
NIIKMLNH_03346 4.32e-283 yitF 5.5.1.27 - M ko:K18983 ko00053,map00053 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
NIIKMLNH_03347 8.28e-291 yitG - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
NIIKMLNH_03348 1.29e-196 yitH - - K - - - Acetyltransferase (GNAT) domain
NIIKMLNH_03349 2.16e-93 - - - S - - - Acetyltransferase (GNAT) domain
NIIKMLNH_03350 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
NIIKMLNH_03351 1.75e-76 yitK - - S ko:K09767 - ko00000 Belongs to the UPF0234 family
NIIKMLNH_03352 2.26e-203 yitL - - S ko:K00243 - ko00000 protein conserved in bacteria
NIIKMLNH_03353 4.16e-122 - - - - - - - -
NIIKMLNH_03354 1.42e-218 - - - - - - - -
NIIKMLNH_03355 3.29e-127 - - - S - - - Sporulation delaying protein SdpA
NIIKMLNH_03356 8.46e-77 - - - K - - - Transcriptional regulator PadR-like family
NIIKMLNH_03357 3.53e-119 - - - - - - - -
NIIKMLNH_03358 4.59e-59 yitR - - S - - - Domain of unknown function (DUF3784)
NIIKMLNH_03359 0.0 nprB 3.4.24.28 - E ko:K01400,ko:K08777 ko02024,map02024 ko00000,ko00001,ko01000,ko01002 Peptidase M4
NIIKMLNH_03360 2.62e-201 yitS - - S - - - protein conserved in bacteria
NIIKMLNH_03361 2.29e-189 yitT - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
NIIKMLNH_03362 1.96e-93 ipi - - S - - - Intracellular proteinase inhibitor
NIIKMLNH_03363 1.01e-25 - - - S - - - Protein of unknown function (DUF3813)
NIIKMLNH_03364 1.52e-198 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
NIIKMLNH_03365 5.05e-185 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
NIIKMLNH_03366 4.63e-68 yitW - - S - - - metal-sulfur cluster biosynthetic enzyme
NIIKMLNH_03367 1.74e-31 - - - S - - - Proteolipid membrane potential modulator
NIIKMLNH_03368 0.0 yitY - - C - - - D-arabinono-1,4-lactone oxidase
NIIKMLNH_03369 3.24e-114 yitZ - - G - - - Major Facilitator Superfamily
NIIKMLNH_03370 1.18e-251 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NIIKMLNH_03371 1.01e-292 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NIIKMLNH_03372 1.27e-175 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
NIIKMLNH_03373 5.65e-277 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
NIIKMLNH_03374 1.91e-261 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
NIIKMLNH_03375 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase ammonia chain
NIIKMLNH_03376 4.27e-225 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NIIKMLNH_03377 2.51e-39 yjzC - - S - - - YjzC-like protein
NIIKMLNH_03378 2.17e-23 yjzD - - S - - - Protein of unknown function (DUF2929)
NIIKMLNH_03379 2.42e-182 yjaU - - I - - - carboxylic ester hydrolase activity
NIIKMLNH_03380 5.84e-129 yjaV - - - - - - -
NIIKMLNH_03381 3.7e-234 med - - S ko:K05519,ko:K07335 - ko00000,ko03000 Transcriptional activator protein med
NIIKMLNH_03382 1.07e-35 comZ - - S ko:K02254 - ko00000,ko02044 ComZ
NIIKMLNH_03383 4.43e-30 yjzB - - - - - - -
NIIKMLNH_03384 1.61e-221 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NIIKMLNH_03385 3.06e-302 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NIIKMLNH_03386 8.73e-189 yjaZ - - O - - - Zn-dependent protease
NIIKMLNH_03387 1.76e-233 appD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NIIKMLNH_03388 1.2e-236 appF - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NIIKMLNH_03389 0.0 appA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
NIIKMLNH_03390 6.73e-216 appB - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NIIKMLNH_03391 1.03e-208 appC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NIIKMLNH_03392 3.18e-190 yjbA - - S - - - Belongs to the UPF0736 family
NIIKMLNH_03393 6.15e-235 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
NIIKMLNH_03394 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
NIIKMLNH_03395 3.44e-211 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NIIKMLNH_03396 7.55e-212 oppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NIIKMLNH_03397 1.12e-248 oppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NIIKMLNH_03398 1.27e-219 oppF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NIIKMLNH_03399 1.36e-259 yjbB - - EGP - - - Major Facilitator Superfamily
NIIKMLNH_03400 8.88e-132 yjbC - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NIIKMLNH_03401 1.01e-87 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NIIKMLNH_03402 1.43e-143 yjbE - - P - - - Integral membrane protein TerC family
NIIKMLNH_03403 4.65e-149 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
NIIKMLNH_03404 1.41e-278 coiA - - S ko:K06198 - ko00000 Competence protein
NIIKMLNH_03405 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
NIIKMLNH_03406 2.68e-28 - - - - - - - -
NIIKMLNH_03407 1.32e-218 yjbH - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
NIIKMLNH_03408 8.58e-94 yjbI - - S ko:K06886 - ko00000 Bacterial-like globin
NIIKMLNH_03409 2.8e-126 yjbJ - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
NIIKMLNH_03410 7.32e-130 yjbK - - S - - - protein conserved in bacteria
NIIKMLNH_03411 5.35e-81 yjbL - - S - - - Belongs to the UPF0738 family
NIIKMLNH_03412 5.06e-145 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 GTP pyrophosphokinase
NIIKMLNH_03413 2.94e-194 nadK 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NIIKMLNH_03414 1.49e-202 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
NIIKMLNH_03415 2.71e-179 prpE 3.1.3.16, 3.6.1.41 - T ko:K01090,ko:K01525 ko00230,map00230 ko00000,ko00001,ko01000 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
NIIKMLNH_03416 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NIIKMLNH_03417 5.7e-177 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NIIKMLNH_03418 2.32e-138 tenI 5.3.99.10 - H ko:K10810 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Transcriptional regulator TenI
NIIKMLNH_03419 1.09e-275 thiO 1.4.3.19, 1.4.5.1 - E ko:K00285,ko:K03153 ko00360,ko00730,ko01100,map00360,map00730,map01100 ko00000,ko00001,ko01000 Glycine oxidase
NIIKMLNH_03420 2.18e-41 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 thiamine diphosphate biosynthetic process
NIIKMLNH_03421 6.78e-174 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
NIIKMLNH_03422 8.78e-238 thiF 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
NIIKMLNH_03423 8.38e-192 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
NIIKMLNH_03424 1.23e-182 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
NIIKMLNH_03425 9.24e-98 yjbX - - S - - - Spore coat protein
NIIKMLNH_03426 4.57e-108 cotZ - - S ko:K06344 - ko00000 Spore coat protein
NIIKMLNH_03427 3.12e-124 cotY - - S ko:K06343 - ko00000 Spore coat protein Z
NIIKMLNH_03428 5.55e-65 cotX - - S ko:K06342 - ko00000 Spore Coat Protein X and V domain
NIIKMLNH_03429 5.19e-22 cotW - - - ko:K06341 - ko00000 -
NIIKMLNH_03430 2.28e-53 cotV - - S ko:K06340 - ko00000 Spore Coat Protein X and V domain
NIIKMLNH_03431 5.88e-74 yjcA - - S - - - Protein of unknown function (DUF1360)
NIIKMLNH_03434 1.88e-52 spoVIF - - S - - - Stage VI sporulation protein F
NIIKMLNH_03435 0.0 yjcD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
NIIKMLNH_03436 6.31e-51 - - - - - - - -
NIIKMLNH_03437 7.75e-94 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NIIKMLNH_03438 9.9e-121 yjcG - - J - - - Belongs to the 2H phosphoesterase superfamily. YjcG family
NIIKMLNH_03439 1.57e-176 yjcH - - P ko:K07214 - ko00000 COG2382 Enterochelin esterase and related enzymes
NIIKMLNH_03440 1.98e-273 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
NIIKMLNH_03441 6.14e-279 metC 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
NIIKMLNH_03442 2.13e-129 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Alanine acetyltransferase
NIIKMLNH_03443 5.32e-267 yjcL - - S - - - Protein of unknown function (DUF819)
NIIKMLNH_03446 1.33e-50 - - - - - - - -
NIIKMLNH_03448 3.34e-295 - - - M - - - nucleic acid phosphodiester bond hydrolysis
NIIKMLNH_03452 3.54e-162 - - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
NIIKMLNH_03453 3.65e-61 yjcS - - S - - - Antibiotic biosynthesis monooxygenase
NIIKMLNH_03454 5.1e-60 yjcN - - - - - - -
NIIKMLNH_03455 0.0 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 transcriptional antiterminator
NIIKMLNH_03456 0.0 manP 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NIIKMLNH_03457 3.3e-236 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
NIIKMLNH_03458 9.24e-76 yjdF3 - - S - - - Protein of unknown function (DUF2992)
NIIKMLNH_03459 3.46e-115 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
NIIKMLNH_03461 3.38e-104 ebsC - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NIIKMLNH_03462 6.12e-40 - - - S - - - Domain of unknown function (DUF4177)
NIIKMLNH_03463 2.31e-69 yjdJ - - S - - - Domain of unknown function (DUF4306)
NIIKMLNH_03464 5.08e-222 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
NIIKMLNH_03466 0.0 yjeA 3.5.1.104 - G ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
NIIKMLNH_03467 2.22e-108 - - - S - - - Protein of unknown function (DUF2690)
NIIKMLNH_03468 1.13e-29 yjfB - - S - - - Putative motility protein
NIIKMLNH_03469 1.16e-212 yjfC - - O - - - Predicted Zn-dependent protease (DUF2268)
NIIKMLNH_03470 3.78e-45 yjgA - - T - - - Protein of unknown function (DUF2809)
NIIKMLNH_03471 4.96e-133 yjgB - - S - - - Domain of unknown function (DUF4309)
NIIKMLNH_03472 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
NIIKMLNH_03473 1.6e-122 yjgD - - S - - - Protein of unknown function (DUF1641)
NIIKMLNH_03475 1.69e-143 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
NIIKMLNH_03477 3.33e-286 yjiB 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
NIIKMLNH_03478 7.18e-279 yjiC - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
NIIKMLNH_03479 1.11e-41 - - - - - - - -
NIIKMLNH_03480 3.54e-188 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
NIIKMLNH_03481 9.04e-156 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
NIIKMLNH_03482 2.79e-175 yjkB - - P ko:K02068 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
NIIKMLNH_03483 1.81e-224 yjlA - - EG - - - Putative multidrug resistance efflux transporter
NIIKMLNH_03484 2.46e-118 yjlB - - S - - - Cupin domain
NIIKMLNH_03485 1.39e-87 yjlC - - S - - - Protein of unknown function (DUF1641)
NIIKMLNH_03486 2.15e-280 yjlD 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
NIIKMLNH_03487 0.0 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
NIIKMLNH_03488 4.34e-314 - - - G ko:K03292 - ko00000 symporter YjmB
NIIKMLNH_03489 2.08e-241 allD 1.1.1.350 - C ko:K00073 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000 Belongs to the LDH2 MDH2 oxidoreductase family
NIIKMLNH_03490 4.21e-242 yjmD 1.1.1.380 - E ko:K08322 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
NIIKMLNH_03491 2.18e-270 uxuA 4.2.1.8 - G ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of D-mannonate
NIIKMLNH_03492 2.23e-195 yjmF - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
NIIKMLNH_03493 3.93e-289 exuT - - G ko:K03535,ko:K08191 - ko00000,ko02000 Sugar (and other) transporter
NIIKMLNH_03494 9.87e-238 exuR - - K ko:K02529 - ko00000,ko03000 transcriptional
NIIKMLNH_03495 0.0 uxaB 1.1.1.58 - G ko:K00041 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 tagaturonate reductase activity
NIIKMLNH_03496 0.0 uxaA 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
NIIKMLNH_03497 9.2e-167 yjnA - - S ko:K07090 - ko00000 membrane transporter protein
NIIKMLNH_03498 2.71e-103 yjoA - - S - - - DinB family
NIIKMLNH_03499 5e-313 VCP - - O - - - AAA domain (dynein-related subfamily)
NIIKMLNH_03500 8.59e-272 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
NIIKMLNH_03502 1.79e-55 - - - S - - - YCII-related domain
NIIKMLNH_03503 7.58e-218 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
NIIKMLNH_03504 2.24e-79 yjqA - - S - - - Bacterial PH domain
NIIKMLNH_03505 1.58e-138 yjqB - - S - - - Pfam:DUF867
NIIKMLNH_03506 1.76e-159 yjqC - - P ko:K07217 - ko00000 Catalase
NIIKMLNH_03507 7.3e-143 xkdA - - E - - - IrrE N-terminal-like domain
NIIKMLNH_03508 2.01e-74 xre - - K - - - Helix-turn-helix XRE-family like proteins
NIIKMLNH_03510 4.36e-202 xkdB - - K - - - sequence-specific DNA binding
NIIKMLNH_03511 1.44e-150 xkdC - - L - - - Bacterial dnaA protein
NIIKMLNH_03515 8.12e-110 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
NIIKMLNH_03516 1.31e-176 xtmA - - L ko:K07474 - ko00000 phage terminase small subunit
NIIKMLNH_03517 0.0 xtmB - - S ko:K06909 - ko00000 phage terminase, large subunit
NIIKMLNH_03518 0.0 yqbA - - S - - - portal protein
NIIKMLNH_03519 9.88e-177 xkdF3 - - L - - - Putative phage serine protease XkdF
NIIKMLNH_03520 3.91e-217 xkdG - - S - - - Phage capsid family
NIIKMLNH_03521 4.68e-82 yqbG - - S - - - Protein of unknown function (DUF3199)
NIIKMLNH_03522 5.02e-84 yqbH - - S - - - Domain of unknown function (DUF3599)
NIIKMLNH_03523 9.69e-114 xkdI - - S - - - Bacteriophage HK97-gp10, putative tail-component
NIIKMLNH_03524 2.36e-100 xkdJ - - - - - - -
NIIKMLNH_03525 0.0 xkdK - - S - - - Phage tail sheath C-terminal domain
NIIKMLNH_03526 6.01e-99 xkdM - - S - - - Phage tail tube protein
NIIKMLNH_03527 9.21e-99 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
NIIKMLNH_03528 0.0 xkdO - - L - - - Transglycosylase SLT domain
NIIKMLNH_03529 1.48e-152 xkdP - - S - - - Lysin motif
NIIKMLNH_03530 2.31e-232 xkdQ - - G - - - NLP P60 protein
NIIKMLNH_03531 6.14e-53 xkdR - - S - - - Protein of unknown function (DUF2577)
NIIKMLNH_03532 5.43e-90 xkdS - - S - - - Protein of unknown function (DUF2634)
NIIKMLNH_03533 1.71e-241 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
NIIKMLNH_03534 3.23e-134 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
NIIKMLNH_03535 4.43e-56 - - - - - - - -
NIIKMLNH_03536 8.61e-228 - - - - - - - -
NIIKMLNH_03537 1.9e-68 xkdW - - S - - - XkdW protein
NIIKMLNH_03538 4.47e-31 xkdX - - - - - - -
NIIKMLNH_03539 4.85e-195 xepA - - - - - - -
NIIKMLNH_03540 2.21e-51 xhlA - - S - - - Haemolysin XhlA
NIIKMLNH_03541 1.15e-52 xhlB - - S - - - SPP1 phage holin
NIIKMLNH_03542 2.16e-207 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
NIIKMLNH_03543 1.78e-31 spoIISB - - S ko:K06389 - ko00000 Stage II sporulation protein SB
NIIKMLNH_03544 3.4e-175 spoIISA - - S ko:K06388 - ko00000 Toxin SpoIISA, type II toxin-antitoxin system
NIIKMLNH_03545 1.54e-225 pit - - P ko:K03306 - ko00000 phosphate transporter
NIIKMLNH_03546 1.85e-144 ykaA - - P ko:K07220 - ko00000 COG1392 Phosphate transport regulator (distant homolog of PhoU)
NIIKMLNH_03547 2.57e-309 steT - - E ko:K03294 - ko00000 amino acid
NIIKMLNH_03548 2.31e-232 ykcA - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
NIIKMLNH_03549 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NIIKMLNH_03550 2.21e-229 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
NIIKMLNH_03552 2.41e-284 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NIIKMLNH_03553 4.74e-178 proG 1.5.1.2 - E ko:K00286,ko:K02239 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko02044 Pyrroline-5-carboxylate reductase
NIIKMLNH_03554 3.85e-194 dppA - - E ko:K16203 - ko00000,ko01000,ko01002 D-aminopeptidase
NIIKMLNH_03555 9.7e-204 dppB - - P ko:K16200 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NIIKMLNH_03556 3.02e-224 dppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NIIKMLNH_03557 2.23e-235 dppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NIIKMLNH_03558 0.0 dppE - - E ko:K16199 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
NIIKMLNH_03560 2.17e-221 ykfA 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
NIIKMLNH_03561 1.97e-256 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
NIIKMLNH_03562 9.9e-208 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
NIIKMLNH_03563 9.84e-236 ykfD - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NIIKMLNH_03564 8.08e-261 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconolactonase
NIIKMLNH_03565 1.78e-205 ykgA - - E - - - Amidinotransferase
NIIKMLNH_03566 1.55e-119 ykhA - - I - - - Acyl-CoA hydrolase
NIIKMLNH_03567 2.54e-287 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NIIKMLNH_03568 2.11e-16 - - - - - - - -
NIIKMLNH_03569 3.95e-167 ykjA - - S - - - Protein of unknown function (DUF421)
NIIKMLNH_03570 6.42e-128 ykkA - - S - - - Protein of unknown function (DUF664)
NIIKMLNH_03571 2.43e-126 ykkB - - J - - - COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NIIKMLNH_03572 1.27e-72 ykkC - - P ko:K18924 - ko00000,ko00002,ko02000 Multidrug resistance protein
NIIKMLNH_03573 1.36e-66 ykkD - - P ko:K18925 - ko00000,ko00002,ko02000 Multidrug resistance protein
NIIKMLNH_03574 1.66e-217 purU 3.5.1.10 - F ko:K01433 ko00630,ko00670,map00630,map00670 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
NIIKMLNH_03575 1.75e-254 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NIIKMLNH_03576 2.18e-287 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NIIKMLNH_03577 2.39e-93 ohrA - - O - - - Organic hydroperoxide resistance protein
NIIKMLNH_03578 1.42e-97 ohrR - - K - - - COG1846 Transcriptional regulators
NIIKMLNH_03579 2.34e-93 ohrB - - O - - - Organic hydroperoxide resistance protein
NIIKMLNH_03580 5.67e-115 guaD 3.5.4.3 - FJ ko:K01487 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 COG0590 Cytosine adenosine deaminases
NIIKMLNH_03581 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NIIKMLNH_03582 1.49e-225 isp - - O ko:K13275 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
NIIKMLNH_03583 3.99e-193 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NIIKMLNH_03584 1.27e-173 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
NIIKMLNH_03585 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NIIKMLNH_03586 1.39e-127 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
NIIKMLNH_03587 4.05e-141 ykoF - - S - - - YKOF-related Family
NIIKMLNH_03588 1.28e-160 ykoG - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NIIKMLNH_03589 1.89e-310 ykoH - - T - - - Histidine kinase
NIIKMLNH_03590 2.64e-143 ykoI - - S - - - Peptidase propeptide and YPEB domain
NIIKMLNH_03591 1.3e-111 ykoJ - - S - - - Peptidase propeptide and YPEB domain
NIIKMLNH_03592 1.45e-08 - - - - - - - -
NIIKMLNH_03594 9.86e-300 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
NIIKMLNH_03595 1.49e-70 tnrA - - K - - - transcriptional
NIIKMLNH_03596 3.3e-25 - - - - - - - -
NIIKMLNH_03597 3.04e-36 ykoL - - - - - - -
NIIKMLNH_03598 9.83e-106 ykoM - - K ko:K15973 - ko00000,ko03000 transcriptional
NIIKMLNH_03599 1.33e-278 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
NIIKMLNH_03600 2.48e-129 ykoP - - G - - - polysaccharide deacetylase
NIIKMLNH_03601 1.77e-197 ykoQ - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
NIIKMLNH_03602 0.0 ykoS - - - - - - -
NIIKMLNH_03603 1.35e-237 ykoT - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
NIIKMLNH_03604 0.0 ligD 6.5.1.1 - L ko:K01971 ko03450,map03450 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA ligase
NIIKMLNH_03605 5.1e-204 ku - - L ko:K10979 ko03450,map03450 ko00000,ko00001,ko03400 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
NIIKMLNH_03606 0.0 ykoW 2.7.7.65 - T ko:K21023 ko02025,map02025 ko00000,ko00001,ko01000 Diguanylate cyclase
NIIKMLNH_03607 1.71e-143 ykoX - - S - - - membrane-associated protein
NIIKMLNH_03608 4.63e-227 ykoY - - P - - - COG0861 Membrane protein TerC, possibly involved in tellurium resistance
NIIKMLNH_03609 1.8e-167 sigI - - K ko:K03093 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NIIKMLNH_03610 9.93e-200 rsgI - - S - - - Anti-sigma factor N-terminus
NIIKMLNH_03611 1.4e-36 sspD - - S ko:K06421 - ko00000 small acid-soluble spore protein
NIIKMLNH_03612 1.55e-159 ykrK - - S - - - Domain of unknown function (DUF1836)
NIIKMLNH_03613 3.97e-199 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
NIIKMLNH_03614 2.58e-310 ktrD - - P - - - COG0168 Trk-type K transport systems, membrane components
NIIKMLNH_03616 1.77e-28 ykzE - - - - - - -
NIIKMLNH_03617 3.34e-244 ykrP - - G - - - COG3594 Fucose 4-O-acetylase and related acetyltransferases
NIIKMLNH_03618 0.0 kinE 2.7.13.3 - T ko:K13533 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NIIKMLNH_03619 2.76e-115 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NIIKMLNH_03621 1.43e-94 mtnA 5.3.1.23 - E ko:K08963 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
NIIKMLNH_03622 6.06e-146 mtnA 5.3.1.23 - E ko:K08963 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
NIIKMLNH_03623 4.98e-293 mtnK 2.7.1.100 - F ko:K00899 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
NIIKMLNH_03624 5.71e-193 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
NIIKMLNH_03625 2.78e-295 mtnE - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
NIIKMLNH_03626 9.72e-295 mtnW 5.3.2.5 - G ko:K08965 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
NIIKMLNH_03627 1.77e-175 mtnX 3.1.3.87 - E ko:K08966 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
NIIKMLNH_03628 3.71e-146 mtnB 4.2.1.109 - E ko:K08964 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
NIIKMLNH_03629 3.03e-123 mtnD 1.13.11.53, 1.13.11.54 - S ko:K08967 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
NIIKMLNH_03630 8.82e-68 - - - S - - - Protein of unknown function (DUF1232)
NIIKMLNH_03632 5.84e-95 eag - - - - - - -
NIIKMLNH_03633 0.0 kinD 2.7.13.3 - T ko:K13532 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
NIIKMLNH_03634 5.17e-99 ykvE - - K ko:K15973 - ko00000,ko03000 transcriptional
NIIKMLNH_03635 4.91e-170 motB - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
NIIKMLNH_03636 3.23e-178 motA - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
NIIKMLNH_03637 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
NIIKMLNH_03638 2.02e-228 ykvI - - S - - - membrane
NIIKMLNH_03639 6.42e-161 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NIIKMLNH_03640 6.96e-105 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
NIIKMLNH_03641 3.56e-179 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
NIIKMLNH_03642 2.36e-125 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NIIKMLNH_03643 2.8e-81 ykvN - - K - - - Transcriptional regulator
NIIKMLNH_03644 9.35e-173 ykvO - - IQ - - - Enoyl-(Acyl carrier protein) reductase
NIIKMLNH_03645 3.01e-272 - - - M - - - Glycosyl transferases group 1
NIIKMLNH_03646 7.56e-48 - 3.5.1.104 - M ko:K22278 - ko00000,ko01000 LysM domain
NIIKMLNH_03647 4.11e-203 - - - G - - - Glycosyl hydrolases family 18
NIIKMLNH_03648 8.95e-61 ykvR - - S - - - Protein of unknown function (DUF3219)
NIIKMLNH_03649 5.43e-35 ykvS - - S - - - protein conserved in bacteria
NIIKMLNH_03650 2.5e-39 - - - - - - - -
NIIKMLNH_03651 9.09e-142 ykvT 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell Wall Hydrolase
NIIKMLNH_03652 3.74e-301 ykvU - - S - - - COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NIIKMLNH_03653 2.76e-115 stoA - - CO - - - thiol-disulfide
NIIKMLNH_03654 0.0 zosA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
NIIKMLNH_03655 3.99e-09 - - - - - - - -
NIIKMLNH_03656 3.73e-262 ykvY 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
NIIKMLNH_03657 5.43e-229 ykvZ - - K - - - Transcriptional regulator
NIIKMLNH_03659 1.14e-166 glcT - - K ko:K03480,ko:K03488 - ko00000,ko03000 antiterminator
NIIKMLNH_03660 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NIIKMLNH_03661 1.51e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPr
NIIKMLNH_03662 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NIIKMLNH_03663 1.54e-51 splA - - S ko:K06315 - ko00000,ko03000 Transcriptional regulator
NIIKMLNH_03664 2.49e-256 splB 4.1.99.14 - L ko:K03716 - ko00000,ko01000 Spore photoproduct lyase
NIIKMLNH_03665 2.53e-161 ykwB - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NIIKMLNH_03666 0.0 mcpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
NIIKMLNH_03667 4.02e-203 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
NIIKMLNH_03668 1.68e-17 vgb - - H ko:K18235 - ko00000,ko01000,ko01504 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid
NIIKMLNH_03669 4.4e-171 ykwD - - J - - - protein with SCP PR1 domains
NIIKMLNH_03670 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
NIIKMLNH_03671 0.0 kinA 2.7.13.3 - T ko:K02491 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NIIKMLNH_03672 1.46e-283 patA - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
NIIKMLNH_03673 1.05e-22 - - - - - - - -
NIIKMLNH_03674 4.95e-216 cheV - - T ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 Chemotaxis protein CheV
NIIKMLNH_03675 3.71e-110 ykyB - - S - - - YkyB-like protein
NIIKMLNH_03676 2.55e-305 ykuC - - EGP - - - COG0477 Permeases of the major facilitator superfamily
NIIKMLNH_03677 5.84e-115 ykuD - - S - - - protein conserved in bacteria
NIIKMLNH_03678 3.48e-212 ykuE - - S ko:K07098 - ko00000 Metallophosphoesterase
NIIKMLNH_03679 2.6e-182 fadH 1.3.1.34 - IQ ko:K00219 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NIIKMLNH_03680 1.76e-298 ykuI - - T - - - Diguanylate phosphodiesterase
NIIKMLNH_03681 5.16e-50 ykuJ - - S - - - protein conserved in bacteria
NIIKMLNH_03682 3.73e-121 - - - S ko:K09776 - ko00000 Ribonuclease H-like
NIIKMLNH_03683 7.83e-38 ykzF - - S - - - Antirepressor AbbA
NIIKMLNH_03684 5.15e-100 ykuL - - S - - - CBS domain
NIIKMLNH_03685 6.52e-216 ccpC - - K - - - Transcriptional regulator
NIIKMLNH_03686 1.44e-109 - - - C ko:K03839 - ko00000 Flavodoxin domain
NIIKMLNH_03687 6.07e-223 ykuO - - - - - - -
NIIKMLNH_03688 1.03e-101 fld - - C ko:K03839 - ko00000 Flavodoxin
NIIKMLNH_03689 1.31e-125 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NIIKMLNH_03690 7.35e-272 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NIIKMLNH_03691 7.23e-51 ykuS - - S - - - Belongs to the UPF0180 family
NIIKMLNH_03692 4.1e-181 ykuT - - M ko:K22044 - ko00000,ko02000 Mechanosensitive ion channel
NIIKMLNH_03693 9.78e-130 ykuU - - O - - - Alkyl hydroperoxide reductase
NIIKMLNH_03694 6.01e-104 ykuV - - CO - - - thiol-disulfide
NIIKMLNH_03695 1.78e-120 rok - - K - - - Repressor of ComK
NIIKMLNH_03696 8.12e-199 yknT - - - ko:K06437 - ko00000 -
NIIKMLNH_03697 3.75e-141 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
NIIKMLNH_03698 7.59e-245 moeB 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
NIIKMLNH_03699 2.04e-311 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 molybdopterin
NIIKMLNH_03700 8.11e-121 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
NIIKMLNH_03701 1.1e-108 moaE 2.8.1.12 - H ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 COG0314 Molybdopterin converting factor, large subunit
NIIKMLNH_03702 2.82e-44 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NIIKMLNH_03703 0.0 yknU - - V ko:K06147,ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
NIIKMLNH_03704 0.0 yknV - - V ko:K02021,ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
NIIKMLNH_03705 1.08e-149 yknW - - S - - - Yip1 domain
NIIKMLNH_03706 1.5e-229 yknX - - M ko:K02005,ko:K13888 - ko00000,ko00002,ko02000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NIIKMLNH_03707 7.12e-159 yknY - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NIIKMLNH_03708 6.71e-266 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
NIIKMLNH_03709 7.41e-176 fruR - - K ko:K03436 - ko00000,ko03000 Transcriptional regulator
NIIKMLNH_03710 2.35e-214 pfkB 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
NIIKMLNH_03711 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
NIIKMLNH_03712 1.42e-133 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
NIIKMLNH_03713 7.71e-52 ykoA - - - - - - -
NIIKMLNH_03714 0.0 ykpA - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NIIKMLNH_03715 2.75e-213 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NIIKMLNH_03716 2.07e-303 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
NIIKMLNH_03717 1.09e-18 - - - S - - - Uncharacterized protein YkpC
NIIKMLNH_03718 6.17e-234 mreBH - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod-share determining protein MreBH
NIIKMLNH_03719 2.63e-58 abrB - - K ko:K06284 - ko00000,ko03000 of stationary sporulation gene expression
NIIKMLNH_03720 4.4e-305 kinC 2.7.13.3 - T ko:K07698 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
NIIKMLNH_03721 1.7e-198 ykqA - - P - - - Gamma-glutamyl cyclotransferase, AIG2-like
NIIKMLNH_03722 1.68e-148 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
NIIKMLNH_03723 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NIIKMLNH_03724 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NIIKMLNH_03725 8.98e-42 ykzG - - S - - - Belongs to the UPF0356 family
NIIKMLNH_03726 1.18e-186 ykrA - - S - - - hydrolases of the HAD superfamily
NIIKMLNH_03727 3.96e-131 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NIIKMLNH_03728 1.26e-07 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
NIIKMLNH_03729 1.06e-138 ykyA - - L - - - Putative cell-wall binding lipoprotein
NIIKMLNH_03730 1.06e-258 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NIIKMLNH_03731 3.52e-227 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NIIKMLNH_03732 1.47e-301 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NIIKMLNH_03733 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NIIKMLNH_03734 4.55e-83 slp - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
NIIKMLNH_03735 0.0 speA 4.1.1.17, 4.1.1.19 - E ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Arginine
NIIKMLNH_03736 6.37e-55 yktA - - S - - - Belongs to the UPF0223 family
NIIKMLNH_03737 2.15e-151 yktB - - S - - - Belongs to the UPF0637 family
NIIKMLNH_03738 4.48e-35 ykzI - - - - - - -
NIIKMLNH_03739 2.61e-192 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase
NIIKMLNH_03740 5.78e-98 ykzC - - S - - - Acetyltransferase (GNAT) family
NIIKMLNH_03741 4.98e-221 - - - Q - - - Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
NIIKMLNH_03742 0.0 mpl 3.4.24.28, 3.4.24.29 - E ko:K01400,ko:K01401,ko:K19351 ko01503,ko05150,map01503,map05150 ko00000,ko00001,ko01000,ko01002 Peptidase M4
NIIKMLNH_03743 0.0 ylaA - - - - - - -
NIIKMLNH_03744 4.12e-56 ylaB - - - - - - -
NIIKMLNH_03745 1.69e-113 ylaC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NIIKMLNH_03747 2.3e-55 ylaE - - - - - - -
NIIKMLNH_03748 2.21e-30 - - - S - - - Family of unknown function (DUF5325)
NIIKMLNH_03749 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
NIIKMLNH_03750 4.4e-63 ylaH - - S - - - YlaH-like protein
NIIKMLNH_03751 3.64e-43 ylaI - - S - - - protein conserved in bacteria
NIIKMLNH_03752 2.97e-127 ylaJ - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NIIKMLNH_03753 5.64e-315 ylaK - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
NIIKMLNH_03754 9.32e-112 ylaL - - S - - - Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NIIKMLNH_03755 3.49e-219 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
NIIKMLNH_03756 6.94e-59 ylaN - - S - - - Belongs to the UPF0358 family
NIIKMLNH_03757 7.05e-271 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
NIIKMLNH_03758 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NIIKMLNH_03759 2.85e-212 ctaA - - O ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 ko00000,ko00001,ko00002,ko03029 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
NIIKMLNH_03760 1.7e-208 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
NIIKMLNH_03761 2.38e-252 ctaC 1.9.3.1 - C ko:K02275 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
NIIKMLNH_03762 0.0 ctaD 1.9.3.1 - C ko:K02274 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NIIKMLNH_03763 1.84e-145 ctaE 1.9.3.1 - C ko:K02276 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
NIIKMLNH_03764 6.09e-70 ctaF 1.9.3.1 - C ko:K02277 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
NIIKMLNH_03765 1.21e-213 ctaG - - S ko:K02862 - ko00000 cytochrome c oxidase
NIIKMLNH_03766 1.61e-81 ylbA - - S - - - YugN-like family
NIIKMLNH_03767 1.08e-97 ylbB - - T - - - COG0517 FOG CBS domain
NIIKMLNH_03768 2.44e-253 ylbC - - S - - - protein with SCP PR1 domains
NIIKMLNH_03769 9.28e-89 ylbD - - S - - - Putative coat protein
NIIKMLNH_03770 1.73e-48 ylbE - - S - - - YlbE-like protein
NIIKMLNH_03771 2.34e-97 ylbF - - S - - - Belongs to the UPF0342 family
NIIKMLNH_03772 4.36e-52 ylbG - - S - - - UPF0298 protein
NIIKMLNH_03773 2.47e-125 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
NIIKMLNH_03774 1.55e-110 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NIIKMLNH_03775 9.11e-281 ylbJ - - S - - - Sporulation integral membrane protein YlbJ
NIIKMLNH_03776 2.56e-176 ylbK - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
NIIKMLNH_03777 7.81e-239 ylbL - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
NIIKMLNH_03778 8.29e-292 ylbM - - S - - - Belongs to the UPF0348 family
NIIKMLNH_03780 6.94e-117 ylbN - - S ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
NIIKMLNH_03781 1.71e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
NIIKMLNH_03782 4.72e-107 ylbO - - S ko:K06314 - ko00000,ko03000 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
NIIKMLNH_03783 1.33e-115 ylbP - - K - - - n-acetyltransferase
NIIKMLNH_03784 3.6e-211 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NIIKMLNH_03785 0.0 bshC - - S ko:K22136 - ko00000 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
NIIKMLNH_03786 9.82e-102 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
NIIKMLNH_03787 1.66e-218 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NIIKMLNH_03788 3.42e-68 ftsL - - D - - - Essential cell division protein
NIIKMLNH_03789 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
NIIKMLNH_03790 0.0 spoVD - - M ko:K08384 ko00550,map00550 ko00000,ko00001,ko01011 stage V sporulation protein D
NIIKMLNH_03791 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NIIKMLNH_03792 9.59e-220 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NIIKMLNH_03793 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NIIKMLNH_03794 6.64e-237 spoVE - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
NIIKMLNH_03795 1.28e-255 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NIIKMLNH_03796 3.74e-211 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
NIIKMLNH_03797 3.37e-178 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NIIKMLNH_03798 2.23e-142 ylxW - - S - - - protein conserved in bacteria
NIIKMLNH_03799 4.89e-122 ylxX - - S - - - protein conserved in bacteria
NIIKMLNH_03800 5.37e-76 sbp - - S - - - small basic protein
NIIKMLNH_03801 4.88e-299 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NIIKMLNH_03802 1.84e-260 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NIIKMLNH_03803 0.0 bpr - - O ko:K13276 - ko00000,ko01000,ko01002,ko03110 COG1404 Subtilisin-like serine proteases
NIIKMLNH_03804 7.14e-219 spoIIGA - - M ko:K06383 - ko00000,ko01000,ko01002 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
NIIKMLNH_03805 1.48e-160 sigE - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NIIKMLNH_03806 7.99e-180 sigG - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NIIKMLNH_03807 1.83e-187 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
NIIKMLNH_03808 0.0 argE - - E ko:K20895 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Acetylornithine deacetylase
NIIKMLNH_03809 3.58e-51 ylmC - - S - - - sporulation protein
NIIKMLNH_03810 9.17e-204 ylmD - - S ko:K05810 - ko00000,ko01000 Belongs to the multicopper oxidase YfiH RL5 family
NIIKMLNH_03811 9.03e-162 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NIIKMLNH_03812 1.28e-86 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NIIKMLNH_03813 1.22e-53 ylmG - - S ko:K02221 - ko00000,ko02044 membrane
NIIKMLNH_03814 1.49e-178 ylmH - - S - - - conserved protein, contains S4-like domain
NIIKMLNH_03815 6.44e-100 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
NIIKMLNH_03816 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NIIKMLNH_03817 3.74e-82 ylyA - - T - - - COG1734 DnaK suppressor protein
NIIKMLNH_03818 2.71e-103 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NIIKMLNH_03819 3.52e-225 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
NIIKMLNH_03820 4.45e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NIIKMLNH_03821 1.97e-291 pyrP - - F ko:K02824 - ko00000,ko02000 Xanthine uracil
NIIKMLNH_03822 1.72e-212 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
NIIKMLNH_03823 9.71e-317 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NIIKMLNH_03824 1.31e-269 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
NIIKMLNH_03825 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarB family
NIIKMLNH_03826 1.75e-181 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
NIIKMLNH_03827 4.26e-221 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NIIKMLNH_03828 6.56e-164 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NIIKMLNH_03829 8.96e-149 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NIIKMLNH_03831 3.44e-181 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
NIIKMLNH_03832 4.05e-227 cysP - - P ko:K16331 - ko00000,ko02000 phosphate transporter
NIIKMLNH_03833 8.77e-284 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
NIIKMLNH_03834 1.59e-141 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
NIIKMLNH_03835 5.9e-185 cobA 2.1.1.107 - H ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
NIIKMLNH_03836 5.9e-187 sirB 4.99.1.4 - S ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sirohydrochlorin ferrochelatase
NIIKMLNH_03837 4.41e-106 sirC 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Siroheme synthase
NIIKMLNH_03838 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
NIIKMLNH_03839 0.0 yloB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 COG0474 Cation transport ATPase
NIIKMLNH_03840 8.41e-202 yloC - - S - - - stress-induced protein
NIIKMLNH_03841 3.97e-54 ylzA - - S ko:K09777 - ko00000 Belongs to the UPF0296 family
NIIKMLNH_03842 5.73e-143 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
NIIKMLNH_03843 6.21e-39 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NIIKMLNH_03844 5.13e-286 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NIIKMLNH_03845 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NIIKMLNH_03846 4.8e-109 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NIIKMLNH_03847 7.08e-223 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NIIKMLNH_03848 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NIIKMLNH_03849 8.79e-263 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
NIIKMLNH_03850 2.05e-179 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
NIIKMLNH_03851 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
NIIKMLNH_03852 1.12e-214 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NIIKMLNH_03853 9.44e-153 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
NIIKMLNH_03854 1.35e-155 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
NIIKMLNH_03855 7.06e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
NIIKMLNH_03856 3.65e-78 yloU - - S - - - protein conserved in bacteria
NIIKMLNH_03857 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
NIIKMLNH_03858 5.89e-153 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
NIIKMLNH_03859 1.19e-201 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
NIIKMLNH_03860 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NIIKMLNH_03861 6.22e-121 fapR - - K - - - Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
NIIKMLNH_03862 8.33e-230 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NIIKMLNH_03863 1.86e-218 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
NIIKMLNH_03864 3.5e-167 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
NIIKMLNH_03865 1.15e-43 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
NIIKMLNH_03866 3.71e-141 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NIIKMLNH_03867 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
NIIKMLNH_03868 3.38e-227 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NIIKMLNH_03869 1.67e-114 - - - - - - - -
NIIKMLNH_03870 5.64e-66 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NIIKMLNH_03871 3.95e-308 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NIIKMLNH_03872 1.13e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
NIIKMLNH_03873 1.2e-49 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
NIIKMLNH_03874 9.77e-80 ylqD - - S - - - YlqD protein
NIIKMLNH_03875 7.5e-122 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NIIKMLNH_03876 2.41e-177 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
NIIKMLNH_03877 8.14e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NIIKMLNH_03878 1.4e-200 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NIIKMLNH_03879 5.83e-175 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NIIKMLNH_03880 0.0 ylqG - - - - - - -
NIIKMLNH_03881 1.7e-59 ylqH - - S ko:K04061 - ko00000,ko02044 homolog of the cytoplasmic domain of flagellar protein FhlB
NIIKMLNH_03882 6.77e-269 sucC 6.2.1.5 - C ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
NIIKMLNH_03883 3.09e-213 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NIIKMLNH_03884 3.62e-215 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
NIIKMLNH_03885 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NIIKMLNH_03886 2.22e-313 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NIIKMLNH_03887 1.13e-217 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 tyrosine recombinase XerC
NIIKMLNH_03888 3.01e-120 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NIIKMLNH_03889 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NIIKMLNH_03890 1.95e-175 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NIIKMLNH_03891 1.62e-83 flgB - - N ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
NIIKMLNH_03892 1.46e-96 flgC - - N ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the flagella basal body rod proteins family
NIIKMLNH_03893 5.5e-53 fliE - - N ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-basal body
NIIKMLNH_03894 0.0 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
NIIKMLNH_03895 6.08e-230 fliG - - N ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
NIIKMLNH_03896 7.8e-144 fliH - - NU ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 COG1317 Flagellar biosynthesis type III secretory pathway protein
NIIKMLNH_03897 3.5e-307 fliI 3.6.3.14 - NU ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 COG1157 Flagellar biosynthesis type III secretory pathway ATPase
NIIKMLNH_03898 1.79e-91 fliJ - - N ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar biosynthesis chaperone
NIIKMLNH_03899 7.29e-72 ylxF - - S - - - MgtE intracellular N domain
NIIKMLNH_03900 3.04e-303 fliK - - N ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-length control protein
NIIKMLNH_03901 2.81e-96 flgD - - N ko:K02389 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod modification protein
NIIKMLNH_03902 1.66e-174 flgG - - N ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod
NIIKMLNH_03903 5.59e-78 fliL - - N ko:K02415 - ko00000,ko02035 Controls the rotational direction of flagella during chemotaxis
NIIKMLNH_03904 6.61e-231 fliM - - N ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
NIIKMLNH_03905 1.38e-253 fliY - - N ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NIIKMLNH_03906 1.22e-76 cheY - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 response regulator
NIIKMLNH_03907 3.07e-134 fliZ - - N ko:K02418 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthesis protein, FliO
NIIKMLNH_03908 1.21e-141 fliP - - N ko:K02419 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Plays a role in the flagellum-specific transport system
NIIKMLNH_03909 2.13e-49 fliQ - - N ko:K02420 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Role in flagellar biosynthesis
NIIKMLNH_03910 1.47e-170 fliR - - N ko:K02421 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthetic protein FliR
NIIKMLNH_03911 3.89e-244 flhB - - N ko:K02401 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NIIKMLNH_03912 0.0 flhA - - N ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NIIKMLNH_03913 9.37e-255 flhF - - N ko:K02404 - ko00000,ko02035 Flagellar biosynthesis regulator FlhF
NIIKMLNH_03914 6.33e-200 ylxH - - D ko:K04562 - ko00000,ko02035 Belongs to the ParA family
NIIKMLNH_03915 2.58e-252 cheB 3.1.1.61, 3.5.1.44 - NT ko:K03412 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
NIIKMLNH_03916 0.0 cheA 2.7.13.3 - NT ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 COG0643 Chemotaxis protein histidine kinase and related kinases
NIIKMLNH_03917 1.56e-103 cheW - - NT ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 COG0835 Chemotaxis signal transduction protein
NIIKMLNH_03918 5.06e-144 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
NIIKMLNH_03919 3.34e-112 cheD 3.5.1.44 - NT ko:K03411 ko02030,map02030 ko00000,ko00001,ko01000,ko02035 Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
NIIKMLNH_03920 1.33e-175 sigD - - K ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NIIKMLNH_03921 4e-100 ylxL - - - - - - -
NIIKMLNH_03922 1.49e-168 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
NIIKMLNH_03923 9.82e-202 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NIIKMLNH_03924 5.82e-163 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
NIIKMLNH_03925 9.6e-119 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NIIKMLNH_03926 3.84e-187 uppS 2.5.1.31 - I ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NIIKMLNH_03927 5.77e-179 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
NIIKMLNH_03928 1.39e-276 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
NIIKMLNH_03929 6.84e-294 rasP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
NIIKMLNH_03930 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NIIKMLNH_03931 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NIIKMLNH_03932 1.34e-104 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
NIIKMLNH_03933 5.49e-261 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
NIIKMLNH_03934 2.01e-57 ylxR - - K ko:K07742 - ko00000 nucleic-acid-binding protein implicated in transcription termination
NIIKMLNH_03935 6.16e-63 ylxQ - - J - - - ribosomal protein
NIIKMLNH_03936 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NIIKMLNH_03937 1.11e-59 ylxP - - S ko:K09764 - ko00000 protein conserved in bacteria
NIIKMLNH_03938 3.29e-75 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NIIKMLNH_03939 6.04e-220 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NIIKMLNH_03940 4.48e-230 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
NIIKMLNH_03941 7.11e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NIIKMLNH_03942 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
NIIKMLNH_03943 7.18e-233 ylxY - - G - - - Sporulation protein, polysaccharide deacetylase
NIIKMLNH_03944 1.62e-295 mlpA - - S - - - Belongs to the peptidase M16 family
NIIKMLNH_03945 1.53e-56 ymxH - - S - - - YlmC YmxH family
NIIKMLNH_03946 5.3e-208 dpaA - - CH ko:K06410 - ko00000 Dipicolinate synthase subunit A
NIIKMLNH_03947 4.73e-140 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
NIIKMLNH_03948 2.36e-247 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NIIKMLNH_03949 4.9e-283 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
NIIKMLNH_03950 6.39e-201 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NIIKMLNH_03951 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NIIKMLNH_03952 5.01e-171 tepA - - OU - - - COG0740 Protease subunit of ATP-dependent Clp proteases
NIIKMLNH_03953 4.94e-44 - - - S - - - YlzJ-like protein
NIIKMLNH_03954 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
NIIKMLNH_03955 1.28e-171 ymfC - - K ko:K03710 - ko00000,ko03000 Transcriptional regulator
NIIKMLNH_03956 5.1e-266 ymfD - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
NIIKMLNH_03957 1.1e-297 albE - - S - - - Peptidase M16
NIIKMLNH_03958 2.77e-308 ymfH - - S - - - zinc protease
NIIKMLNH_03959 3.01e-166 ymfI 1.1.1.100 - S ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
NIIKMLNH_03960 5.13e-55 ymfJ - - S - - - Protein of unknown function (DUF3243)
NIIKMLNH_03961 3.91e-183 ymfK - - S - - - Protein of unknown function (DUF3388)
NIIKMLNH_03962 8.75e-177 ymfM - - S ko:K15539 - ko00000 protein conserved in bacteria
NIIKMLNH_03963 3.34e-132 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NIIKMLNH_03964 1.76e-298 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
NIIKMLNH_03965 4.7e-239 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NIIKMLNH_03966 6.36e-277 pbpX - - V - - - Beta-lactamase
NIIKMLNH_03967 4.25e-306 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
NIIKMLNH_03968 6.18e-195 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 protein conserved in bacteria
NIIKMLNH_03969 2.44e-49 spoVS - - S ko:K06416 - ko00000 Stage V sporulation protein S
NIIKMLNH_03970 1.38e-251 tdh 1.1.1.103 - C ko:K00060 ko00260,map00260 ko00000,ko00001,ko01000 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
NIIKMLNH_03971 1.69e-277 kbl 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
NIIKMLNH_03972 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NIIKMLNH_03973 1.12e-76 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
NIIKMLNH_03974 1.74e-119 cotE - - S ko:K06328 - ko00000 Spore coat protein
NIIKMLNH_03975 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NIIKMLNH_03976 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NIIKMLNH_03977 6.68e-92 - - - S - - - Regulatory protein YrvL
NIIKMLNH_03978 3.24e-126 ymcC - - S - - - Membrane
NIIKMLNH_03979 6.31e-142 pksA - - K - - - Transcriptional regulator
NIIKMLNH_03980 4.02e-167 pksB 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 Polyketide biosynthesis
NIIKMLNH_03981 4.37e-207 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
NIIKMLNH_03983 1.4e-237 pksD - - Q ko:K15328 - ko00000,ko01008 Acyl transferase domain
NIIKMLNH_03984 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
NIIKMLNH_03985 5.46e-51 acpK - - IQ ko:K15337 - ko00000,ko01008 Phosphopantetheine attachment site
NIIKMLNH_03986 3.58e-302 - 2.3.1.179 - I ko:K00646,ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NIIKMLNH_03987 6.55e-312 pksG 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
NIIKMLNH_03988 2.29e-180 - - - I ko:K15312 - ko00000,ko01008 enoyl-CoA hydratase
NIIKMLNH_03989 1.56e-176 pksI - - I ko:K15313 - ko00000,ko01008 Belongs to the enoyl-CoA hydratase isomerase family
NIIKMLNH_03990 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
NIIKMLNH_03991 0.0 - - - Q ko:K13612 - ko00000,ko01004,ko01008 Polyketide synthase of type I
NIIKMLNH_03992 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
NIIKMLNH_03993 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
NIIKMLNH_03994 0.0 - - - HQ ko:K13615 - ko00000,ko01004,ko01008 Beta-ketoacyl synthase
NIIKMLNH_03995 1.13e-293 cypA 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
NIIKMLNH_03996 8.03e-81 ymzB - - - - - - -
NIIKMLNH_03997 8.93e-206 - - - S - - - Metallo-beta-lactamase superfamily
NIIKMLNH_03998 0.0 aprX - - O ko:K17734 - ko00000,ko01000,ko01002 Belongs to the peptidase S8 family
NIIKMLNH_04000 3.96e-163 ymaC - - S - - - Replication protein
NIIKMLNH_04001 2.44e-104 ymaD - - O - - - redox protein, regulator of disulfide bond formation
NIIKMLNH_04002 1.57e-73 ebrB - - P ko:K03297,ko:K11814,ko:K11815 - ko00000,ko00002,ko02000 COG2076 Membrane transporters of cations and cationic drugs
NIIKMLNH_04003 2.02e-66 ebrA - - P ko:K11814 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
NIIKMLNH_04005 5.41e-76 ymaF - - S - - - YmaF family
NIIKMLNH_04006 1.38e-223 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NIIKMLNH_04007 1.28e-45 hfq - - J ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
NIIKMLNH_04008 1.63e-31 - - - - - - - -
NIIKMLNH_04009 1.2e-30 ymzA - - - - - - -
NIIKMLNH_04010 5.01e-66 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
NIIKMLNH_04011 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NIIKMLNH_04012 1.65e-243 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NIIKMLNH_04013 1.51e-139 - - - - - - - -
NIIKMLNH_04014 3.32e-149 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
NIIKMLNH_04015 2.29e-226 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
NIIKMLNH_04016 1.82e-293 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NIIKMLNH_04017 4.78e-310 ynbB - - P - - - COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
NIIKMLNH_04018 4.05e-89 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 transcriptional
NIIKMLNH_04019 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
NIIKMLNH_04020 1.61e-173 - - - L - - - Belongs to the 'phage' integrase family
NIIKMLNH_04023 4.77e-07 - - - K - - - Cro/C1-type HTH DNA-binding domain
NIIKMLNH_04024 1.68e-07 - - - K - - - Helix-turn-helix domain
NIIKMLNH_04029 5.46e-94 - - - L - - - Conserved phage C-terminus (Phg_2220_C)
NIIKMLNH_04030 1.84e-20 - - - L ko:K02315 - ko00000,ko03032 IstB-like ATP binding protein
NIIKMLNH_04035 2.78e-08 - - - - - - - -
NIIKMLNH_04041 7.92e-68 - - - M - - - ArpU family transcriptional regulator
NIIKMLNH_04042 9.22e-94 - - - L - - - Phage integrase family
NIIKMLNH_04043 1.9e-08 - - - - - - - -
NIIKMLNH_04046 5.31e-82 - - - S - - - HNH endonuclease
NIIKMLNH_04047 2.49e-25 - - - - - - - -
NIIKMLNH_04048 4.07e-89 - - - S - - - Phage terminase, small subunit
NIIKMLNH_04049 2.05e-279 - - - S - - - Phage Terminase
NIIKMLNH_04050 1.28e-14 - - - - - - - -
NIIKMLNH_04051 3.21e-271 - - - S - - - Phage portal protein
NIIKMLNH_04052 1.33e-134 - - - S - - - peptidase activity
NIIKMLNH_04053 5.11e-229 - - - S - - - capsid protein
NIIKMLNH_04054 1.57e-08 - - - S - - - peptidoglycan catabolic process
NIIKMLNH_04055 1.73e-38 - - - S - - - peptidoglycan catabolic process
NIIKMLNH_04056 7.45e-34 - - - S - - - Phage gp6-like head-tail connector protein
NIIKMLNH_04057 8.29e-19 - - - S - - - Phage head-tail joining protein
NIIKMLNH_04058 3.77e-63 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
NIIKMLNH_04059 4.06e-40 - - - - - - - -
NIIKMLNH_04060 9.75e-79 - - - - - - - -
NIIKMLNH_04061 9.94e-35 - - - - - - - -
NIIKMLNH_04062 4.09e-16 - - - - - - - -
NIIKMLNH_04063 0.0 - - - S - - - peptidoglycan catabolic process
NIIKMLNH_04064 4.84e-142 - - - S - - - Phage tail protein
NIIKMLNH_04065 3.26e-307 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Prophage endopeptidase tail
NIIKMLNH_04066 1.37e-61 - - - - - - - -
NIIKMLNH_04069 2.13e-64 - - - S - - - Domain of unknown function (DUF2479)
NIIKMLNH_04072 1.32e-76 - - - S - - - Bacteriophage holin family
NIIKMLNH_04073 2.43e-167 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
NIIKMLNH_04074 4.02e-109 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
NIIKMLNH_04075 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
NIIKMLNH_04077 4.94e-13 - - - - - - - -
NIIKMLNH_04081 7.88e-119 - - - M - - - Glycosyltransferase like family
NIIKMLNH_04082 5.8e-156 - - - H - - - Methionine biosynthesis protein MetW
NIIKMLNH_04083 2.03e-246 - - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
NIIKMLNH_04084 3.14e-274 - - - H - - - N-terminal domain of galactosyltransferase
NIIKMLNH_04086 9.87e-123 ynaD - - J - - - Acetyltransferase (GNAT) domain
NIIKMLNH_04087 4.93e-95 - - - S - - - CAAX protease self-immunity
NIIKMLNH_04088 2.38e-11 ywlA - - S - - - Uncharacterised protein family (UPF0715)
NIIKMLNH_04089 1.39e-134 - - - S - - - Domain of unknown function (DUF3885)
NIIKMLNH_04092 6.13e-110 - - - E - - - phosphoribosylanthranilate isomerase activity
NIIKMLNH_04093 0.0 xynP - - G ko:K03292 - ko00000 MFS/sugar transport protein
NIIKMLNH_04094 0.0 xynB 3.2.1.37 GH43 G ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
NIIKMLNH_04095 1.23e-275 xylR - - GK - - - ROK family
NIIKMLNH_04096 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
NIIKMLNH_04097 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 xylulose kinase
NIIKMLNH_04098 6.15e-146 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
NIIKMLNH_04099 0.0 - - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NIIKMLNH_04101 4.16e-279 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NIIKMLNH_04103 5.49e-107 - - - S - - - Protein of unknown function (DUF2691)
NIIKMLNH_04104 3.51e-101 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
NIIKMLNH_04107 1.53e-207 - - - S - - - Thymidylate synthase
NIIKMLNH_04108 8.27e-40 - - - - - - - -
NIIKMLNH_04110 5.34e-166 - - - S - - - Domain of unknown function, YrpD
NIIKMLNH_04113 2.37e-34 tatA - - U ko:K03116,ko:K03117,ko:K03646 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02000,ko02044 protein secretion
NIIKMLNH_04114 1.04e-94 - - - - - - - -
NIIKMLNH_04115 1.81e-103 yndB - - S - - - Activator of Hsp90 ATPase homolog 1-like protein
NIIKMLNH_04118 0.0 yndD1 - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
NIIKMLNH_04119 3.94e-250 yndE7 - - U ko:K06311 - ko00000,ko02000 Spore germination
NIIKMLNH_04120 7.59e-287 - - - S ko:K06293,ko:K06312 - ko00000 Spore germination protein
NIIKMLNH_04121 1.25e-196 yndG - - S - - - DoxX-like family
NIIKMLNH_04122 4.04e-148 - - - S - - - Domain of unknown function (DUF4166)
NIIKMLNH_04123 0.0 yndJ - - S - - - YndJ-like protein
NIIKMLNH_04125 6.31e-173 yndL - - S - - - Replication protein
NIIKMLNH_04126 1.32e-96 yndM - - S - - - Protein of unknown function (DUF2512)
NIIKMLNH_04127 1.74e-101 fosB - - H ko:K11210,ko:K21252 - ko00000,ko01000,ko01504 Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
NIIKMLNH_04128 7.22e-142 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NIIKMLNH_04129 8.5e-65 yneA - - D - - - Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
NIIKMLNH_04130 3.97e-145 yneB - - L - - - resolvase
NIIKMLNH_04131 1.15e-43 ynzC - - S - - - UPF0291 protein
NIIKMLNH_04132 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NIIKMLNH_04133 2.18e-106 yneE - - S - - - Sporulation inhibitor of replication protein sirA
NIIKMLNH_04134 4.36e-39 yneF - - S ko:K09976 - ko00000 UPF0154 protein
NIIKMLNH_04135 4.59e-21 ynzD - - S - - - Spo0E like sporulation regulatory protein
NIIKMLNH_04136 4.13e-165 ccdA - - O ko:K06196 - ko00000,ko02000 cytochrome c biogenesis protein
NIIKMLNH_04137 2.12e-77 ccdB - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 cheY-homologous receiver domain
NIIKMLNH_04138 3.57e-98 yneJ - - O - - - COG4846 Membrane protein involved in cytochrome C biogenesis
NIIKMLNH_04139 3.97e-97 yneK - - S - - - Protein of unknown function (DUF2621)
NIIKMLNH_04140 2.35e-84 cotM - - O ko:K06335 - ko00000 Spore coat protein
NIIKMLNH_04141 5.65e-27 sspP - - S ko:K06433 - ko00000 Belongs to the SspP family
NIIKMLNH_04142 3.27e-21 sspO - - S ko:K06432 - ko00000 Belongs to the SspO family
NIIKMLNH_04143 0.0 citB 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NIIKMLNH_04144 3.07e-119 yneN - - CO - - - alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NIIKMLNH_04145 9.26e-10 - - - S - - - Fur-regulated basic protein B
NIIKMLNH_04147 6.62e-48 tlp - - S ko:K06434 - ko00000 Belongs to the Tlp family
NIIKMLNH_04148 1.4e-95 yneP - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
NIIKMLNH_04149 4.68e-71 yneQ - - - - - - -
NIIKMLNH_04150 8.97e-65 yneR - - S - - - Belongs to the HesB IscA family
NIIKMLNH_04151 3.86e-122 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NIIKMLNH_04152 1.21e-90 yneT - - S ko:K06929 - ko00000 CoA-binding protein
NIIKMLNH_04153 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NIIKMLNH_04154 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NIIKMLNH_04155 1.82e-18 - - - - - - - -
NIIKMLNH_04156 4.16e-73 ynfC - - - - - - -
NIIKMLNH_04157 0.0 alsT - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
NIIKMLNH_04158 0.0 bglC5 3.2.1.4 GH5,GH9 G ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 PFAM glycoside hydrolase family 5
NIIKMLNH_04160 2.36e-315 ynfF 3.2.1.136 GH5 M ko:K15924 - ko00000,ko01000 Belongs to the glycosyl hydrolase 30 family
NIIKMLNH_04161 0.0 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
NIIKMLNH_04162 1.72e-103 yngA - - S - - - membrane
NIIKMLNH_04163 2.74e-210 yngB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
NIIKMLNH_04164 2.01e-134 yngC - - S - - - membrane-associated protein
NIIKMLNH_04165 7.09e-294 yngD - - S ko:K07097 - ko00000 phosphohydrolase (DHH superfamily)
NIIKMLNH_04166 0.0 yngE - - I - - - COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
NIIKMLNH_04167 6.03e-175 yngF - - I - - - Belongs to the enoyl-CoA hydratase isomerase family
NIIKMLNH_04168 6.46e-210 yngG 4.1.3.4 - E ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA lyase
NIIKMLNH_04169 2.4e-41 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin carboxyl carrier protein
NIIKMLNH_04170 5.47e-314 yngH 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
NIIKMLNH_04171 0.0 yngI - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
NIIKMLNH_04172 3.09e-267 yngJ 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
NIIKMLNH_04173 0.0 yngK - - T - - - Glycosyl hydrolase-like 10
NIIKMLNH_04174 6.08e-84 yngL - - S - - - Protein of unknown function (DUF1360)
NIIKMLNH_04175 0.0 - 6.3.2.14 - Q ko:K02364,ko:K15656,ko:K15668 ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024 ko00000,ko00001,ko01000,ko01008 amino acid activation for nonribosomal peptide biosynthetic process
NIIKMLNH_04176 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NIIKMLNH_04177 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NIIKMLNH_04178 0.0 - - - Q ko:K15665 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NIIKMLNH_04179 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NIIKMLNH_04180 0.0 dacC 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
NIIKMLNH_04181 7.83e-240 yoxA 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
NIIKMLNH_04182 9.8e-313 yoeA - - V - - - MATE efflux family protein
NIIKMLNH_04183 7.14e-128 yoeB - - S - - - IseA DL-endopeptidase inhibitor
NIIKMLNH_04185 1.14e-124 - - - L - - - Integrase
NIIKMLNH_04186 3.31e-47 yoeD - - G - - - Helix-turn-helix domain
NIIKMLNH_04187 0.0 ggt 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
NIIKMLNH_04188 8.4e-199 gltR1 - - K ko:K21959 - ko00000,ko03000 Transcriptional regulator
NIIKMLNH_04189 4.88e-236 yogA - - C ko:K13955 - ko00000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
NIIKMLNH_04190 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
NIIKMLNH_04191 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
NIIKMLNH_04192 2.61e-205 gltC - - K ko:K09681 - ko00000,ko03000 Transcriptional regulator
NIIKMLNH_04193 9.09e-260 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NIIKMLNH_04194 2.72e-185 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NIIKMLNH_04195 5.37e-79 rtp - - K - - - Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
NIIKMLNH_04196 4.59e-159 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
NIIKMLNH_04197 3.16e-50 yoxC - - S - - - Bacterial protein of unknown function (DUF948)
NIIKMLNH_04198 4.25e-173 yoxB - - - - - - -
NIIKMLNH_04199 3.84e-121 yoaA 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NIIKMLNH_04200 6.14e-298 yoaB - - EGP - - - the major facilitator superfamily
NIIKMLNH_04201 0.0 lsrK 2.7.1.189 - G ko:K11216 ko02024,map02024 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
NIIKMLNH_04202 3.36e-234 yoaD 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NIIKMLNH_04203 0.0 yoaE - - C - - - belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NIIKMLNH_04204 2.53e-45 yoaF - - - - - - -
NIIKMLNH_04206 1.46e-19 - - - - - - - -
NIIKMLNH_04207 2.99e-55 - - - S - - - Protein of unknown function (DUF4025)
NIIKMLNH_04208 3.18e-282 yoaH - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 methyl-accepting chemotaxis protein

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)