ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
PFOHNOAK_00001 5.59e-316 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PFOHNOAK_00002 1.99e-71 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
PFOHNOAK_00003 2.12e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PFOHNOAK_00004 4.45e-140 jag - - S ko:K06346 - ko00000 single-stranded nucleic acid binding R3H
PFOHNOAK_00005 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PFOHNOAK_00006 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
PFOHNOAK_00007 2.29e-164 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
PFOHNOAK_00008 6.61e-195 noc - - D ko:K03497 - ko00000,ko03000,ko03036,ko04812 Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
PFOHNOAK_00009 1.18e-173 soj - - D ko:K03496 - ko00000,ko03036,ko04812 COG1192 ATPases involved in chromosome partitioning
PFOHNOAK_00010 1.43e-189 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
PFOHNOAK_00011 4.91e-144 yyaC - - S - - - Sporulation protein YyaC
PFOHNOAK_00012 1.27e-61 yhhY - - K - - - FR47-like protein
PFOHNOAK_00013 4.77e-225 yyaD - - S - - - Membrane
PFOHNOAK_00014 1.82e-45 yyzM - - S - - - protein conserved in bacteria
PFOHNOAK_00015 0.0 yyaE - - C - - - Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
PFOHNOAK_00016 5.42e-254 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
PFOHNOAK_00017 2.9e-61 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
PFOHNOAK_00018 4.77e-99 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
PFOHNOAK_00019 1.11e-49 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PFOHNOAK_00020 1.21e-134 adaA - - K ko:K13530 - ko00000,ko01000,ko03000,ko03400 Transcriptional regulator
PFOHNOAK_00021 2.28e-126 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PFOHNOAK_00022 5.24e-181 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
PFOHNOAK_00023 4.66e-230 ccpB - - K - - - Transcriptional regulator
PFOHNOAK_00024 3.43e-88 yyaH 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PFOHNOAK_00025 7.51e-316 - - - G ko:K08369 - ko00000,ko02000 Sugar (and other) transporter
PFOHNOAK_00026 5.73e-208 yyaK - - S ko:K07052 - ko00000 CAAX protease self-immunity
PFOHNOAK_00027 0.0 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
PFOHNOAK_00028 3.45e-30 yyaL - - O ko:K06888 - ko00000 Highly conserved protein containing a thioredoxin domain
PFOHNOAK_00029 3.3e-127 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
PFOHNOAK_00030 1.33e-144 - - - K - - - Bacterial transcription activator, effector binding domain
PFOHNOAK_00031 9.5e-32 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
PFOHNOAK_00032 1.05e-165 - - - EG - - - EamA-like transporter family
PFOHNOAK_00033 6.9e-316 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
PFOHNOAK_00034 1.93e-175 bdh 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
PFOHNOAK_00035 6.64e-208 - - - K - - - Transcriptional regulator
PFOHNOAK_00036 9.24e-85 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
PFOHNOAK_00037 6.47e-209 - - - M - - - Domain of Unknown Function (DUF1259)
PFOHNOAK_00038 1.85e-99 yybA - - K - - - transcriptional
PFOHNOAK_00039 1.09e-193 ydeO - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
PFOHNOAK_00040 6.79e-90 - - - K - - - Winged helix DNA-binding domain
PFOHNOAK_00041 9.83e-148 ydgI - - C - - - nitroreductase
PFOHNOAK_00042 1.12e-73 ypaA - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
PFOHNOAK_00043 1.39e-200 - - - G - - - Major Facilitator Superfamily
PFOHNOAK_00044 1.33e-99 - - - S - - - PFAM DinB family protein
PFOHNOAK_00045 5.42e-149 - - - K - - - FCD domain
PFOHNOAK_00046 0.0 sacC3 3.2.1.65 GH32 G ko:K01212 ko00500,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
PFOHNOAK_00047 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 levansucrase activity
PFOHNOAK_00048 4.82e-196 ypaH - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
PFOHNOAK_00049 2.95e-211 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
PFOHNOAK_00050 2.64e-86 yybR - - K - - - Transcriptional regulator
PFOHNOAK_00051 2.25e-109 cotF - - M ko:K06329 - ko00000 Spore coat protein
PFOHNOAK_00053 2.48e-204 yybS - - S - - - membrane
PFOHNOAK_00054 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
PFOHNOAK_00055 1.58e-95 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
PFOHNOAK_00056 1.45e-158 - - - KLT - - - COG0515 Serine threonine protein kinase
PFOHNOAK_00057 2.15e-157 - - - S - - - GlcNAc-PI de-N-acetylase
PFOHNOAK_00058 8.3e-309 - - - M - - - Glycosyltransferase Family 4
PFOHNOAK_00059 1.27e-294 - - - S - - - Carbamoyl-phosphate synthase L chain, ATP binding domain
PFOHNOAK_00060 6.38e-259 - - - S - - - Ecdysteroid kinase
PFOHNOAK_00061 2.61e-298 - - - M - - - Glycosyltransferase Family 4
PFOHNOAK_00062 5.12e-25 yycC - - K - - - YycC-like protein
PFOHNOAK_00064 6.11e-36 yycD - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
PFOHNOAK_00065 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
PFOHNOAK_00066 4.33e-92 yycE - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PFOHNOAK_00067 1.55e-315 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PFOHNOAK_00072 1.51e-172 yycF - - T ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PFOHNOAK_00073 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PFOHNOAK_00074 0.0 yycH - - S - - - protein conserved in bacteria
PFOHNOAK_00075 2.31e-193 yycI - - S - - - protein conserved in bacteria
PFOHNOAK_00076 1.98e-191 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
PFOHNOAK_00077 1.34e-277 yyxA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PFOHNOAK_00078 1.41e-12 phoP1 - - KT ko:K02483 - ko00000,ko02022 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PFOHNOAK_00079 6.89e-313 - 2.7.13.3 - T ko:K02484 - ko00000,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
PFOHNOAK_00080 3.82e-240 thiF 2.7.7.73 - H ko:K03148 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 ThiF family
PFOHNOAK_00081 0.0 - - - - - - - -
PFOHNOAK_00082 6.06e-257 - - - S - - - Major Facilitator Superfamily
PFOHNOAK_00083 0.0 - - - S - - - ABC transporter
PFOHNOAK_00084 7.53e-188 - 1.14.11.27 - P ko:K10277 - ko00000,ko01000,ko03036 peptidyl-arginine hydroxylation
PFOHNOAK_00085 0.0 rocR - - KT ko:K06714 - ko00000,ko03000 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
PFOHNOAK_00086 2.69e-57 sdpR - - K - - - transcriptional
PFOHNOAK_00087 3.6e-85 yvaZ - - S - - - Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
PFOHNOAK_00088 6.81e-295 rocD 2.6.1.13 - E ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko01007 Catalyzes the interconversion of ornithine to glutamate semialdehyde
PFOHNOAK_00089 0.0 rocE - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
PFOHNOAK_00090 2.64e-212 rocF 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
PFOHNOAK_00091 1.51e-258 - - - S ko:K06361,ko:K06365,ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Histidine kinase
PFOHNOAK_00093 9.78e-112 yycN - - K - - - Acetyltransferase
PFOHNOAK_00094 5.26e-234 - - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
PFOHNOAK_00095 9.69e-171 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
PFOHNOAK_00096 1.22e-272 yycP - - - - - - -
PFOHNOAK_00099 1.01e-105 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PFOHNOAK_00100 1.18e-222 - - - - - - - -
PFOHNOAK_00102 1.08e-64 - - - - - - - -
PFOHNOAK_00104 1.01e-128 - - - D - - - Protein of unknown function (DUF3732)
PFOHNOAK_00105 2.73e-33 - - - S - - - Cytotoxic
PFOHNOAK_00106 4.5e-20 - - - - - - - -
PFOHNOAK_00107 3.29e-26 - - - E - - - IrrE N-terminal-like domain
PFOHNOAK_00108 1.75e-231 - - - S - - - Fusaric acid resistance protein-like
PFOHNOAK_00109 1.34e-233 pucA 1.17.1.4 - O ko:K00087,ko:K07402 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
PFOHNOAK_00110 4.46e-111 pucB 1.17.1.4, 2.7.7.76 - S ko:K00087,ko:K07141 ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120 ko00000,ko00001,ko00002,ko01000 MobA-like NTP transferase domain
PFOHNOAK_00111 0.0 - - - C - - - COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
PFOHNOAK_00112 7.45e-195 - - - C - - - COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
PFOHNOAK_00113 2.74e-107 pucE 1.2.5.3 - C ko:K03518 - ko00000,ko01000 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
PFOHNOAK_00114 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Firmicute fructose-1,6-bisphosphatase
PFOHNOAK_00115 3.55e-312 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
PFOHNOAK_00116 3.95e-292 - - - S - - - Fic/DOC family
PFOHNOAK_00117 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 Alkyl hydroperoxide reductase
PFOHNOAK_00118 1.61e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Alkyl hydroperoxide reductase
PFOHNOAK_00119 1.44e-157 - - - E - - - Ring-cleavage extradiol dioxygenase
PFOHNOAK_00120 1.84e-95 yxaI - - S - - - membrane protein domain
PFOHNOAK_00121 3.64e-254 - - - EGP - - - Major Facilitator Superfamily
PFOHNOAK_00122 1.72e-67 arsR3 - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
PFOHNOAK_00123 1.02e-84 - - - S - - - Family of unknown function (DUF5391)
PFOHNOAK_00124 1.45e-190 yxaL - - S - - - PQQ-like domain
PFOHNOAK_00125 9.34e-317 aldX 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
PFOHNOAK_00126 1e-270 yxbF - - K - - - Bacterial regulatory proteins, tetR family
PFOHNOAK_00127 1.38e-252 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
PFOHNOAK_00128 5.85e-255 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PFOHNOAK_00129 1.07e-131 desR - - T ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PFOHNOAK_00130 7.18e-194 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
PFOHNOAK_00132 0.0 htpG - - O ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Molecular chaperone. Has ATPase activity
PFOHNOAK_00133 6.38e-313 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
PFOHNOAK_00134 6.81e-222 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
PFOHNOAK_00135 1.75e-174 iolR - - K ko:K06608,ko:K11534 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
PFOHNOAK_00136 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
PFOHNOAK_00137 1.15e-198 iolB 5.3.1.30 - G ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
PFOHNOAK_00138 3.82e-229 iolC 2.7.1.92 - G ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
PFOHNOAK_00139 0.0 iolD 3.7.1.22 - E ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
PFOHNOAK_00140 3.12e-221 iolE 4.2.1.44 - H ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
PFOHNOAK_00141 5.22e-294 iolF - - EGP ko:K06610 - ko00000,ko02000 Major facilitator superfamily
PFOHNOAK_00142 4.97e-248 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
PFOHNOAK_00143 6.24e-212 iolH - - G ko:K06605 - ko00000 Xylose isomerase-like TIM barrel
PFOHNOAK_00144 1.7e-200 iolI 5.3.99.11 - G ko:K06606 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
PFOHNOAK_00145 3.17e-201 fbaA 4.1.2.13, 4.1.2.29 - F ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
PFOHNOAK_00146 9.37e-159 yxdJ - - T ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PFOHNOAK_00147 2.38e-225 yxdK 2.7.13.3 - T ko:K11633 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PFOHNOAK_00148 1.89e-181 yxdL - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
PFOHNOAK_00149 0.0 yxdM - - V ko:K11636 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
PFOHNOAK_00150 4.9e-76 yxeA - - S - - - Protein of unknown function (DUF1093)
PFOHNOAK_00151 1.75e-229 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
PFOHNOAK_00152 6.55e-45 - - - - - - - -
PFOHNOAK_00153 5.09e-35 yxeD - - - - - - -
PFOHNOAK_00155 3.81e-33 yxeE - - - - - - -
PFOHNOAK_00158 1.91e-192 yxeH - - S - - - hydrolases of the HAD superfamily
PFOHNOAK_00159 2.36e-219 deoR - - K ko:K05346 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
PFOHNOAK_00160 8.25e-145 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
PFOHNOAK_00161 4.04e-265 nupC - - F ko:K11535 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PFOHNOAK_00162 4.49e-296 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
PFOHNOAK_00163 0.0 hutM - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
PFOHNOAK_00164 7.97e-224 hutG 3.5.3.8 - E ko:K01479 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
PFOHNOAK_00165 1.44e-295 hutI 3.5.2.7 - Q ko:K01468 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Imidazolone-5-propionate hydrolase
PFOHNOAK_00166 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
PFOHNOAK_00167 0.0 hutH 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Histidine ammonia-lyase
PFOHNOAK_00168 2.45e-103 hutP - - K ko:K09683 - ko00000,ko03000 Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
PFOHNOAK_00169 0.0 yxiA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
PFOHNOAK_00170 2.39e-85 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
PFOHNOAK_00171 0.0 - - - L - - - HKD family nuclease
PFOHNOAK_00172 5.98e-95 yxiE - - T - - - Belongs to the universal stress protein A family
PFOHNOAK_00173 8.44e-208 yxxF - - EG - - - EamA-like transporter family
PFOHNOAK_00174 6.09e-254 pelB 4.2.2.10, 4.2.2.2 - G ko:K01728,ko:K01732 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
PFOHNOAK_00175 0.0 wapA - - M - - - COG3209 Rhs family protein
PFOHNOAK_00176 2.14e-52 - - - S - - - Protein of unknown function (DUF2750)
PFOHNOAK_00180 2.93e-78 yxxG - - - - - - -
PFOHNOAK_00181 8.5e-91 yxiG - - - - - - -
PFOHNOAK_00182 2.23e-98 - - - - - - - -
PFOHNOAK_00183 1.7e-135 - - - - - - - -
PFOHNOAK_00185 4.73e-28 - - - - - - - -
PFOHNOAK_00186 1.63e-62 yxiI - - S - - - Protein of unknown function (DUF2716)
PFOHNOAK_00187 4.09e-80 - - - S - - - SMI1-KNR4 cell-wall
PFOHNOAK_00190 0.0 dbpA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
PFOHNOAK_00191 2.88e-279 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 COG2270 Permeases of the major facilitator superfamily
PFOHNOAK_00192 2.35e-133 licT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
PFOHNOAK_00194 9.11e-182 bglS - - M - - - licheninase activity
PFOHNOAK_00195 7.78e-282 citH - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
PFOHNOAK_00196 0.0 katE 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
PFOHNOAK_00197 2.38e-65 yxiS - - - - - - -
PFOHNOAK_00198 9.35e-120 - - - T - - - Domain of unknown function (DUF4163)
PFOHNOAK_00199 5.75e-267 nupG - - F ko:K16323 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PFOHNOAK_00200 1.34e-199 yxjB 2.1.1.187 - Q ko:K00563 - ko00000,ko01000,ko03009 Methyltransferase domain
PFOHNOAK_00201 8.98e-275 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
PFOHNOAK_00202 4.3e-111 yxjI - - S - - - LURP-one-related
PFOHNOAK_00205 5.46e-299 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
PFOHNOAK_00206 1.04e-246 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
PFOHNOAK_00207 2.68e-120 yxkC - - S - - - Domain of unknown function (DUF4352)
PFOHNOAK_00208 3.28e-189 yxkD - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
PFOHNOAK_00209 2.25e-209 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
PFOHNOAK_00210 1.06e-260 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
PFOHNOAK_00211 1.34e-197 yxkH - - G - - - Polysaccharide deacetylase
PFOHNOAK_00212 1.85e-286 cimH - - C - - - COG3493 Na citrate symporter
PFOHNOAK_00213 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
PFOHNOAK_00214 5.3e-240 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase, subunit II
PFOHNOAK_00215 0.0 cydC - - V ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding
PFOHNOAK_00216 0.0 cydD - - V ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding protein
PFOHNOAK_00217 7.23e-200 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PFOHNOAK_00218 0.0 yxlA - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
PFOHNOAK_00219 7.89e-246 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
PFOHNOAK_00220 0.0 katX 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
PFOHNOAK_00221 1.07e-266 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
PFOHNOAK_00222 2.24e-238 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
PFOHNOAK_00223 4.93e-211 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
PFOHNOAK_00224 0.0 ydhP 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
PFOHNOAK_00225 1.35e-300 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PFOHNOAK_00226 1.53e-63 ydhN3 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
PFOHNOAK_00227 2.78e-65 ydhM 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
PFOHNOAK_00228 6.3e-291 arsB - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
PFOHNOAK_00229 8.43e-73 arsR - - K ko:K03892,ko:K22043 - ko00000,ko03000 transcriptional
PFOHNOAK_00230 5.34e-213 cbrA3 - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
PFOHNOAK_00231 1.38e-230 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PFOHNOAK_00232 2.33e-220 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PFOHNOAK_00233 4.59e-145 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
PFOHNOAK_00234 0.0 licR - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
PFOHNOAK_00235 4.46e-66 licB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 transporter subunit IIB
PFOHNOAK_00236 0.0 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PFOHNOAK_00237 1.18e-67 licA 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
PFOHNOAK_00238 0.0 licH 3.2.1.86 GT4 G ko:K01222 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
PFOHNOAK_00239 5.26e-259 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
PFOHNOAK_00240 1.26e-288 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
PFOHNOAK_00241 1.96e-49 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PFOHNOAK_00242 1.48e-292 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 membrane protein involved in D-alanine export
PFOHNOAK_00243 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PFOHNOAK_00244 7.08e-18 - - - S - - - D-Ala-teichoic acid biosynthesis protein
PFOHNOAK_00245 7.57e-215 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
PFOHNOAK_00246 8.78e-150 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 protein conserved in bacteria
PFOHNOAK_00247 1.42e-205 gspA - - M - - - General stress
PFOHNOAK_00248 0.0 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
PFOHNOAK_00249 1.34e-314 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PFOHNOAK_00250 1.51e-87 ywbC 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 glyoxalase
PFOHNOAK_00251 6.95e-283 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
PFOHNOAK_00252 4.11e-174 mta - - K ko:K21743 - ko00000,ko03000 transcriptional
PFOHNOAK_00253 9.1e-38 ywbE - - S - - - Uncharacterized conserved protein (DUF2196)
PFOHNOAK_00254 7.55e-143 ywbG - - M - - - effector of murein hydrolase
PFOHNOAK_00255 9.02e-76 ywbH - - S ko:K06518 - ko00000,ko02000 Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
PFOHNOAK_00256 4.83e-202 ywbI - - K - - - Transcriptional regulator
PFOHNOAK_00257 3.2e-176 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
PFOHNOAK_00258 4.08e-146 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
PFOHNOAK_00259 2.1e-307 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Dyp-type peroxidase family protein
PFOHNOAK_00260 1.21e-142 ywbO - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
PFOHNOAK_00261 3.31e-170 - - - S - - - Streptomycin biosynthesis protein StrF
PFOHNOAK_00262 8.76e-167 - - - H - - - Methionine biosynthesis protein MetW
PFOHNOAK_00264 1.52e-144 - - - K - - - Bacterial regulatory proteins, tetR family
PFOHNOAK_00265 4.03e-80 gtcA - - S - - - GtrA-like protein
PFOHNOAK_00266 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
PFOHNOAK_00267 5.74e-48 ydaS - - S - - - membrane
PFOHNOAK_00268 3.67e-227 qoxA 1.10.3.12 - C ko:K02826 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
PFOHNOAK_00269 0.0 qoxB 1.10.3.12 - C ko:K02827 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PFOHNOAK_00270 4.91e-144 qoxC 1.10.3.12 - C ko:K02828 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
PFOHNOAK_00271 1.31e-81 qoxD 1.10.3.12 - C ko:K02829 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
PFOHNOAK_00272 2.54e-51 ywcE - - S - - - Required for proper spore morphogenesis. Important for spore germination
PFOHNOAK_00273 3.05e-99 ysnE - - K ko:K03829 - ko00000,ko01000 acetyltransferase
PFOHNOAK_00274 7.63e-271 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
PFOHNOAK_00275 3.15e-176 nfrA1 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Oxidoreductase
PFOHNOAK_00276 8.09e-235 ywcH - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PFOHNOAK_00277 0.0 prtS 3.4.21.110, 3.4.21.96 - O ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
PFOHNOAK_00279 1.91e-195 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
PFOHNOAK_00280 0.0 sacP 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
PFOHNOAK_00281 0.0 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
PFOHNOAK_00282 5e-26 ywdA - - - - - - -
PFOHNOAK_00283 4.13e-187 pdxK 2.7.1.35, 2.7.1.49, 2.7.4.7 - H ko:K00868,ko:K00941 ko00730,ko00750,ko01100,map00730,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
PFOHNOAK_00284 1.6e-75 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator PadR-like family
PFOHNOAK_00285 2.34e-114 ywdD - - - - - - -
PFOHNOAK_00287 4.49e-190 ywdF - - S - - - Glycosyltransferase like family 2
PFOHNOAK_00288 7.22e-171 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PFOHNOAK_00289 1.57e-62 ywdI - - S - - - Family of unknown function (DUF5327)
PFOHNOAK_00290 2.19e-290 ywdJ - - F - - - Xanthine uracil
PFOHNOAK_00291 2.17e-76 ywdK - - S - - - small membrane protein
PFOHNOAK_00292 4.89e-85 gerQ - - S ko:K06305 - ko00000 Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
PFOHNOAK_00293 8.69e-182 spsA - - M - - - Spore Coat
PFOHNOAK_00294 0.0 spsB - - M - - - Capsule polysaccharide biosynthesis protein
PFOHNOAK_00295 2.81e-279 spsC 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
PFOHNOAK_00296 7.2e-201 spsD 2.3.1.210 - K ko:K16704 - ko00000,ko01000 Spore Coat
PFOHNOAK_00297 1.18e-272 pseI 2.5.1.56, 2.5.1.97 - M ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 acid synthase
PFOHNOAK_00298 1.68e-170 spsF - - M ko:K07257 - ko00000 Spore Coat
PFOHNOAK_00299 2.12e-228 spsG - - M - - - Spore Coat
PFOHNOAK_00300 5.67e-177 spsI 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
PFOHNOAK_00301 6.14e-232 spsJ 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
PFOHNOAK_00302 2.74e-207 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
PFOHNOAK_00303 9.44e-112 spsL 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Spore Coat
PFOHNOAK_00304 6.37e-77 - - - - - - - -
PFOHNOAK_00305 5.21e-313 rocG 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
PFOHNOAK_00306 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
PFOHNOAK_00307 0.0 rocB - - E - - - arginine degradation protein
PFOHNOAK_00308 0.0 rocC - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
PFOHNOAK_00309 3.84e-262 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
PFOHNOAK_00310 6.44e-283 ywfA - - EGP - - - -transporter
PFOHNOAK_00311 1.4e-146 bacA 4.1.1.100 - E ko:K19546 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
PFOHNOAK_00312 9.82e-176 bacB 5.3.3.19 - S ko:K19547 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
PFOHNOAK_00313 1.56e-178 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PFOHNOAK_00314 0.0 bacD 6.3.2.49 - F ko:K13037 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
PFOHNOAK_00315 9.5e-264 bacE - - EGP ko:K19552 - ko00000,ko02000 Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
PFOHNOAK_00316 6.34e-297 ywfG - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
PFOHNOAK_00317 8.07e-179 ywfH - - IQ ko:K19550 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Enoyl-(Acyl carrier protein) reductase
PFOHNOAK_00318 4.87e-187 ywfI - - C ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko01000 May function as heme-dependent peroxidase
PFOHNOAK_00319 2.03e-225 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 In Salmonella this enzyme is required for ethanolamine catabolism
PFOHNOAK_00320 3.42e-213 - - - S - - - Conserved hypothetical protein 698
PFOHNOAK_00321 2.63e-209 cysL - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
PFOHNOAK_00322 2.81e-198 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
PFOHNOAK_00324 5.3e-225 - - - - - - - -
PFOHNOAK_00327 1.4e-213 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC transporter (permease)
PFOHNOAK_00328 2.15e-207 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
PFOHNOAK_00329 4.59e-121 - - - S - - - membrane
PFOHNOAK_00330 9.26e-69 - - - K ko:K10947 - ko00000,ko03000 PadR family transcriptional regulator
PFOHNOAK_00331 7.1e-145 rsfA_1 - - - ko:K06314 - ko00000,ko03000 -
PFOHNOAK_00332 8.55e-49 ywzC - - S - - - Belongs to the UPF0741 family
PFOHNOAK_00333 0.0 ywfO - - S ko:K06885 - ko00000 COG1078 HD superfamily phosphohydrolases
PFOHNOAK_00334 8.24e-115 ywgA - - - ko:K09388 - ko00000 -
PFOHNOAK_00335 1.91e-313 potE5 - - E ko:K03294 - ko00000 C-terminus of AA_permease
PFOHNOAK_00336 9.43e-90 ywhA - - K - - - Transcriptional regulator
PFOHNOAK_00337 2.37e-34 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 4-oxalocrotonate tautomerase
PFOHNOAK_00338 3.84e-153 ywhC - - S - - - Peptidase family M50
PFOHNOAK_00339 7.83e-123 ywhD - - S - - - YwhD family
PFOHNOAK_00340 7.11e-105 - - - - - - - -
PFOHNOAK_00341 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M ko:K21464 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
PFOHNOAK_00342 1.58e-203 speE 2.5.1.16 - E ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
PFOHNOAK_00343 4.95e-214 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
PFOHNOAK_00346 9.45e-98 - - - CP - - - Membrane
PFOHNOAK_00348 9.48e-43 - - - - - - - -
PFOHNOAK_00349 7.54e-40 ydcG - - K ko:K07729 - ko00000,ko03000 sequence-specific DNA binding
PFOHNOAK_00351 2.85e-89 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
PFOHNOAK_00352 4.79e-57 ywiB - - S - - - protein conserved in bacteria
PFOHNOAK_00353 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
PFOHNOAK_00354 2.76e-269 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
PFOHNOAK_00355 4.46e-166 fnr - - K - - - helix_turn_helix, cAMP Regulatory protein
PFOHNOAK_00356 3.05e-178 ywiC - - S - - - YwiC-like protein
PFOHNOAK_00357 2.91e-109 arfM - - T ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 cyclic nucleotide binding
PFOHNOAK_00358 0.0 narG 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
PFOHNOAK_00359 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase, beta
PFOHNOAK_00360 4.37e-115 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase
PFOHNOAK_00361 3.83e-155 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase (gamma
PFOHNOAK_00362 5.84e-134 - - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
PFOHNOAK_00363 0.0 ywiE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PFOHNOAK_00364 0.0 ywjA - - V ko:K06147 - ko00000,ko02000 ABC transporter
PFOHNOAK_00365 1.13e-58 ywjC - - - - - - -
PFOHNOAK_00366 6.38e-232 uvsE - - L ko:K13281 - ko00000,ko01000 Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
PFOHNOAK_00367 3.32e-283 clsB - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the phospholipase D family. Cardiolipin synthase subfamily
PFOHNOAK_00368 0.0 ywjF - - C - - - COG0247 Fe-S oxidoreductase
PFOHNOAK_00369 6.54e-73 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
PFOHNOAK_00370 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
PFOHNOAK_00371 1.91e-119 ywjG - - S - - - Domain of unknown function (DUF2529)
PFOHNOAK_00372 1.07e-81 spo0F - - T ko:K02490 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG0784 FOG CheY-like receiver
PFOHNOAK_00373 5.51e-204 fbaA 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Aldolase
PFOHNOAK_00374 6.37e-144 tal 2.2.1.2 - G ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
PFOHNOAK_00375 3.21e-303 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PFOHNOAK_00376 1.43e-224 glpX 3.1.3.11 - G ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 fructose-1,6-bisphosphatase
PFOHNOAK_00377 5.13e-304 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
PFOHNOAK_00378 7e-45 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
PFOHNOAK_00379 1.94e-132 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
PFOHNOAK_00380 0.0 ykwA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
PFOHNOAK_00381 1.93e-200 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
PFOHNOAK_00382 4.94e-122 racA - - K ko:K11686 - ko00000,ko03036 Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
PFOHNOAK_00383 3.7e-88 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PFOHNOAK_00384 1.11e-244 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PFOHNOAK_00385 6.39e-199 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
PFOHNOAK_00387 2.08e-79 ywlA - - S - - - Uncharacterised protein family (UPF0715)
PFOHNOAK_00388 1.88e-152 spoIIR - - S ko:K06387 - ko00000 stage II sporulation protein R
PFOHNOAK_00389 7.03e-98 ywlB - - E - - - Belongs to the acetyltransferase family. ArgA subfamily
PFOHNOAK_00390 3.08e-243 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
PFOHNOAK_00391 7.89e-118 mntP - - P - - - Probably functions as a manganese efflux pump
PFOHNOAK_00392 1.2e-100 ywlE 3.1.3.48, 3.9.1.2 - T ko:K01104,ko:K20201 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PFOHNOAK_00393 6.74e-106 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase
PFOHNOAK_00394 3.68e-125 ywlG - - S - - - Belongs to the UPF0340 family
PFOHNOAK_00395 5.69e-299 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PFOHNOAK_00396 9.12e-147 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PFOHNOAK_00397 4.49e-80 atpI - - S ko:K02116 - ko00000,ko00194 ATP synthase
PFOHNOAK_00398 5.19e-168 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
PFOHNOAK_00399 3.01e-36 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PFOHNOAK_00400 1.66e-82 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PFOHNOAK_00401 1.95e-116 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PFOHNOAK_00402 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PFOHNOAK_00403 1.1e-195 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PFOHNOAK_00404 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PFOHNOAK_00405 8.24e-83 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
PFOHNOAK_00406 6.9e-116 ywmA - - - - - - -
PFOHNOAK_00407 1.3e-44 ywzB - - S - - - membrane
PFOHNOAK_00408 3.4e-174 ywmB - - S - - - TATA-box binding
PFOHNOAK_00409 4.75e-304 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PFOHNOAK_00410 6.71e-241 spoIID - - D ko:K06381 - ko00000 Stage II sporulation protein D
PFOHNOAK_00411 1.36e-146 ywmC - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
PFOHNOAK_00412 1.75e-157 ywmD - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
PFOHNOAK_00414 4.3e-185 fdhD - - C ko:K02379 - ko00000 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
PFOHNOAK_00415 2.18e-245 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
PFOHNOAK_00416 6.28e-116 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
PFOHNOAK_00417 5e-106 ywmF - - S - - - Peptidase M50
PFOHNOAK_00418 7.2e-18 csbD - - K - - - CsbD-like
PFOHNOAK_00419 1.94e-66 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
PFOHNOAK_00420 1.07e-81 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
PFOHNOAK_00421 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
PFOHNOAK_00422 3.09e-88 ywnA - - K - - - Transcriptional regulator
PFOHNOAK_00423 1.52e-156 xlnB 3.2.1.8 - G ko:K01181 - ko00000,ko01000 Glycosyl hydrolases family 11
PFOHNOAK_00424 1.1e-76 ywnC - - S - - - Family of unknown function (DUF5362)
PFOHNOAK_00425 0.0 ywnE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PFOHNOAK_00426 5.15e-90 ywnF - - S - - - Family of unknown function (DUF5392)
PFOHNOAK_00428 2.76e-115 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 COG1247 Sortase and related acyltransferases
PFOHNOAK_00429 1.53e-187 spoIIQ - - M ko:K06386 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
PFOHNOAK_00430 5.45e-94 ywnJ - - S - - - VanZ like family
PFOHNOAK_00431 1.17e-131 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 COG0671 Membrane-associated phospholipid phosphatase
PFOHNOAK_00432 3.18e-262 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
PFOHNOAK_00433 1.29e-76 nrgB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
PFOHNOAK_00434 1.32e-291 nrgA - - P ko:K03320 - ko00000,ko02000 Ammonium transporter
PFOHNOAK_00435 1.13e-132 yjgF - - Q - - - Isochorismatase family
PFOHNOAK_00436 8.05e-312 ywoD - - EGP - - - Major facilitator superfamily
PFOHNOAK_00437 0.0 - - - FH ko:K03457,ko:K10975 - ko00000,ko02000 COG1953 Cytosine uracil thiamine allantoin permeases
PFOHNOAK_00438 4.78e-271 ywoG - - EGP - - - COG0477 Permeases of the major facilitator superfamily
PFOHNOAK_00439 7.23e-93 ywoH - - K - - - transcriptional
PFOHNOAK_00440 5.93e-60 spoIIID - - K ko:K06283 - ko00000,ko03000 Stage III sporulation protein D
PFOHNOAK_00441 1.75e-231 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein
PFOHNOAK_00442 2.09e-173 flhO - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
PFOHNOAK_00443 3.66e-185 flhP - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
PFOHNOAK_00444 3.02e-254 rapD - - S ko:K06362 - ko00000,ko01000 aspartate phosphatase
PFOHNOAK_00445 3.15e-98 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
PFOHNOAK_00446 1.87e-74 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
PFOHNOAK_00447 1.07e-89 ywpF - - S - - - YwpF-like protein
PFOHNOAK_00448 4.49e-82 ywpG - - - - - - -
PFOHNOAK_00449 1.47e-76 ssbB - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
PFOHNOAK_00450 1.18e-181 glcR - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
PFOHNOAK_00451 7.2e-200 ywpJ 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
PFOHNOAK_00452 0.0 ywqA - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
PFOHNOAK_00453 0.0 ywqB - - S - - - SWIM zinc finger
PFOHNOAK_00454 1.74e-21 - - - - - - - -
PFOHNOAK_00455 1.95e-149 ywqC - - M ko:K19420 - ko00000 biosynthesis protein
PFOHNOAK_00456 2.58e-156 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
PFOHNOAK_00457 2.05e-179 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 COG4464 Capsular polysaccharide biosynthesis protein
PFOHNOAK_00458 3.4e-311 ywqF 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
PFOHNOAK_00459 1.34e-188 ywqG - - S - - - Domain of unknown function (DUF1963)
PFOHNOAK_00461 2.09e-50 ywqI - - S - - - Family of unknown function (DUF5344)
PFOHNOAK_00462 5.84e-298 ywqJ - - S - - - Pre-toxin TG
PFOHNOAK_00463 9.57e-86 - - - S ko:K21494 - ko00000,ko02048 SMI1 / KNR4 family (SUKH-1)
PFOHNOAK_00464 7.81e-34 - - - S ko:K21494 - ko00000,ko02048 SMI1 / KNR4 family
PFOHNOAK_00465 3.29e-41 - - - S ko:K21494 - ko00000,ko02048 SMI1 / KNR4 family
PFOHNOAK_00466 1.83e-117 - - - - - - - -
PFOHNOAK_00467 1.39e-169 nfi 3.1.21.7 - L ko:K05982 - ko00000,ko01000,ko03400 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
PFOHNOAK_00468 1.39e-201 - - - K - - - Transcriptional regulator
PFOHNOAK_00469 2.12e-120 ywqN - - S - - - NAD(P)H-dependent
PFOHNOAK_00471 2.89e-112 ywrA - - P ko:K07240 - ko00000,ko02000 COG2059 Chromate transport protein ChrA
PFOHNOAK_00472 6.69e-129 ywrB - - P ko:K07240 - ko00000,ko02000 Chromate transporter
PFOHNOAK_00473 1.01e-109 ywrC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
PFOHNOAK_00474 0.0 ywrD 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
PFOHNOAK_00476 5.72e-144 ywrF - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PFOHNOAK_00477 3.39e-25 - - - - - - - -
PFOHNOAK_00478 6.5e-270 cotH - - M ko:K06330 - ko00000 Spore Coat
PFOHNOAK_00479 6.63e-172 cotB - - - ko:K06325 - ko00000 -
PFOHNOAK_00480 4.87e-163 ywrJ - - - - - - -
PFOHNOAK_00481 4.73e-301 ywrK - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
PFOHNOAK_00483 2.18e-214 alsR - - K - - - LysR substrate binding domain
PFOHNOAK_00484 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
PFOHNOAK_00485 5.71e-191 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
PFOHNOAK_00486 7.13e-123 ywrO - - S - - - NADPH-quinone reductase (modulator of drug activity B)
PFOHNOAK_00487 4.13e-116 batE - - T - - - Sh3 type 3 domain protein
PFOHNOAK_00488 1.15e-206 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 COG1879 ABC-type sugar transport system, periplasmic component
PFOHNOAK_00489 5.37e-205 rbsC - - G ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
PFOHNOAK_00490 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
PFOHNOAK_00491 1.32e-83 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
PFOHNOAK_00492 3.28e-200 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PFOHNOAK_00493 7.08e-227 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 transcriptional
PFOHNOAK_00494 3.56e-260 gerKC - - S - - - Spore germination B3/ GerAC like, C-terminal
PFOHNOAK_00495 8.49e-245 - - - E - - - Spore germination protein
PFOHNOAK_00496 2.45e-253 gerKA - - EG ko:K06295 - ko00000 Spore germination protein
PFOHNOAK_00497 1.46e-283 capB - - M ko:K01932 - ko00000,ko01000 COG0769 UDP-N-acetylmuramyl tripeptide synthase
PFOHNOAK_00498 2.95e-91 capC - - S ko:K22116 - ko00000 biosynthesis protein
PFOHNOAK_00499 2.7e-278 capA - - M ko:K07282 - ko00000 enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
PFOHNOAK_00500 4.04e-29 ywtC - - - - - - -
PFOHNOAK_00501 6.9e-298 pgdS - - M - - - COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
PFOHNOAK_00502 2.96e-75 yttA - - S - - - Pfam Transposase IS66
PFOHNOAK_00503 6.17e-201 ywtE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
PFOHNOAK_00504 2.3e-229 ywtF_2 - - K - - - Transcriptional regulator
PFOHNOAK_00505 8.17e-316 ywtG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
PFOHNOAK_00506 0.0 - - - J ko:K07011 - ko00000 Glycosyl transferase family 2
PFOHNOAK_00507 1.12e-267 gerBC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination protein
PFOHNOAK_00508 4.98e-251 gerBB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
PFOHNOAK_00509 0.0 gerBA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
PFOHNOAK_00510 8.41e-235 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
PFOHNOAK_00511 0.0 lytD 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
PFOHNOAK_00512 1.68e-275 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
PFOHNOAK_00513 8.69e-182 tagA 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
PFOHNOAK_00514 2.69e-91 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase
PFOHNOAK_00515 0.0 - - - M - - - Glycosyltransferase like family 2
PFOHNOAK_00516 0.0 tagF 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
PFOHNOAK_00517 5.06e-195 tagG - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
PFOHNOAK_00518 0.0 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
PFOHNOAK_00519 2.64e-211 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
PFOHNOAK_00520 8.19e-267 mnaA 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
PFOHNOAK_00521 4.48e-204 lytR - - K - - - May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
PFOHNOAK_00522 1.86e-64 - - - - - - - -
PFOHNOAK_00523 0.0 lytB - - D - - - Stage II sporulation protein
PFOHNOAK_00524 0.0 lytC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
PFOHNOAK_00525 4.22e-151 tuaA - - M - - - COG2148 Sugar transferases involved in lipopolysaccharide synthesis
PFOHNOAK_00526 0.0 tuaB - - S ko:K03328,ko:K16694,ko:K16695 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
PFOHNOAK_00527 1.85e-284 tuaC - GT4 GM ko:K16697 - ko00000,ko01000,ko01003 Teichuronic acid
PFOHNOAK_00528 9.32e-317 tuaD 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
PFOHNOAK_00529 0.0 tuaE - - M ko:K16705 - ko00000 Teichuronic acid biosynthesis protein
PFOHNOAK_00530 1.17e-146 tuaF - - M ko:K16706 - ko00000 protein involved in exopolysaccharide biosynthesis
PFOHNOAK_00531 2.82e-185 tuaG - GT2 M ko:K16698 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
PFOHNOAK_00532 5.02e-298 tuaH - - M ko:K16699 - ko00000,ko01000,ko01003 Teichuronic acid biosynthesis glycosyltransferase tuaH
PFOHNOAK_00533 3.12e-233 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
PFOHNOAK_00534 2.21e-229 yvhJ - - K - - - Transcriptional regulator
PFOHNOAK_00535 3.43e-154 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 Domain of unknown function (DUF1949)
PFOHNOAK_00536 1.4e-246 degS 2.7.13.3 - T ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
PFOHNOAK_00537 7.16e-163 degU - - KT ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PFOHNOAK_00538 2.07e-202 degV - - S - - - protein conserved in bacteria
PFOHNOAK_00539 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
PFOHNOAK_00540 3.56e-57 comFB - - S ko:K02241 - ko00000,ko00002,ko02044 Late competence development protein ComFB
PFOHNOAK_00541 1.12e-96 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Phosphoribosyl transferase domain
PFOHNOAK_00542 2.23e-97 yvyF - - S - - - flagellar protein
PFOHNOAK_00543 6.14e-53 flgM - - KNU ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 ko00000,ko00001,ko02035 Negative regulator of flagellin synthesis
PFOHNOAK_00544 1.81e-104 yvyG - - NOU - - - FlgN protein
PFOHNOAK_00545 0.0 flgK - - N ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 flagellar hook-associated protein
PFOHNOAK_00546 1.4e-207 flgL - - N ko:K02397 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the bacterial flagellin family
PFOHNOAK_00547 3.27e-107 yviE - - - - - - -
PFOHNOAK_00548 1.18e-94 fliW - - S ko:K13626 - ko00000,ko02035 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
PFOHNOAK_00549 2.67e-43 csrA - - T ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 ko00000,ko00001,ko03019 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
PFOHNOAK_00550 9.98e-154 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
PFOHNOAK_00551 0.0 fliD - - N ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
PFOHNOAK_00552 5.79e-88 fliS - - N ko:K02422 ko02040,map02040 ko00000,ko00001,ko02035 flagellar protein FliS
PFOHNOAK_00553 2.19e-10 fliT - - N ko:K02423 ko02040,map02040 ko00000,ko00001,ko02035 bacterial-type flagellum organization
PFOHNOAK_00554 1.35e-89 - - - - - - - -
PFOHNOAK_00555 3.94e-133 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PFOHNOAK_00556 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
PFOHNOAK_00557 6.64e-233 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PFOHNOAK_00558 6.56e-190 yvjA - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
PFOHNOAK_00559 3.08e-60 cccB - - C ko:K12263,ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
PFOHNOAK_00560 3.53e-158 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
PFOHNOAK_00561 1.73e-195 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
PFOHNOAK_00562 4.04e-303 ywoF - - P - - - Right handed beta helix region
PFOHNOAK_00563 0.0 ctpB 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
PFOHNOAK_00564 2.47e-73 swrA - - S - - - Swarming motility protein
PFOHNOAK_00565 3.57e-281 minJ - - O - - - COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PFOHNOAK_00567 8.04e-296 yvkA - - P - - - -transporter
PFOHNOAK_00568 1.91e-143 yvkB - - K - - - Transcriptional regulator
PFOHNOAK_00569 0.0 yvkC 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Phosphotransferase
PFOHNOAK_00570 2.59e-45 csbA - - S - - - protein conserved in bacteria
PFOHNOAK_00571 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
PFOHNOAK_00572 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
PFOHNOAK_00573 8.07e-44 yvkN - - - - - - -
PFOHNOAK_00574 4.87e-66 yvlA - - - - - - -
PFOHNOAK_00575 9.16e-218 yvlB - - S - - - Putative adhesin
PFOHNOAK_00576 8.1e-36 yvlC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
PFOHNOAK_00577 3.12e-65 yvlD - - S ko:K08972 - ko00000 Membrane
PFOHNOAK_00578 0.0 yvnB - - Q - - - Calcineurin-like phosphoesterase
PFOHNOAK_00579 1.73e-133 yxaF - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
PFOHNOAK_00580 4.29e-171 yvoA - - K ko:K03710 - ko00000,ko03000 transcriptional
PFOHNOAK_00581 2.22e-172 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
PFOHNOAK_00582 6.45e-284 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
PFOHNOAK_00583 3.62e-217 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
PFOHNOAK_00584 1.02e-192 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PFOHNOAK_00585 1.06e-153 ppaX 3.6.1.1 - S ko:K06019 ko00190,map00190 ko00000,ko00001,ko01000 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
PFOHNOAK_00586 5.93e-111 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
PFOHNOAK_00587 4.86e-176 yvpB - - NU - - - protein conserved in bacteria
PFOHNOAK_00588 4.07e-268 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
PFOHNOAK_00589 7.47e-148 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
PFOHNOAK_00590 4.31e-296 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PFOHNOAK_00591 3.35e-137 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
PFOHNOAK_00592 5.69e-147 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
PFOHNOAK_00593 7.64e-166 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
PFOHNOAK_00594 1.09e-173 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
PFOHNOAK_00595 4.7e-143 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the PRA-CH family
PFOHNOAK_00596 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
PFOHNOAK_00597 1.18e-44 - - - - - - - -
PFOHNOAK_00598 1.22e-06 - - - - - - - -
PFOHNOAK_00599 4.65e-157 mprA3 - - T - - - COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PFOHNOAK_00600 5.32e-243 sasA - - T - - - Histidine kinase
PFOHNOAK_00601 0.0 yvcD - - S - - - COG0457 FOG TPR repeat
PFOHNOAK_00602 3.05e-203 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 protein conserved in bacteria
PFOHNOAK_00603 3.13e-226 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
PFOHNOAK_00604 5.15e-113 yvcI 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
PFOHNOAK_00605 2.09e-213 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
PFOHNOAK_00606 8.99e-226 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
PFOHNOAK_00607 1.04e-219 whiA - - K ko:K09762 - ko00000 May be required for sporulation
PFOHNOAK_00608 3.23e-49 crh - - G ko:K11184 - ko00000 Phosphocarrier protein Chr
PFOHNOAK_00609 1.99e-183 yvcN 2.3.1.118 - Q ko:K00675 - ko00000,ko01000 Belongs to the arylamine N-acetyltransferase family
PFOHNOAK_00610 8.99e-104 - - - M - - - Ribonuclease
PFOHNOAK_00611 1.69e-232 yvcT 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PFOHNOAK_00612 4.41e-137 yvdA 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
PFOHNOAK_00613 0.0 yvdB - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
PFOHNOAK_00614 1.3e-69 yvdC - - S - - - MazG nucleotide pyrophosphohydrolase domain
PFOHNOAK_00615 3.78e-137 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
PFOHNOAK_00617 0.0 - - - EGP - - - Sugar (and other) transporter
PFOHNOAK_00618 2.26e-267 yraM - - S - - - PrpF protein
PFOHNOAK_00619 1.12e-208 yraN - - K - - - Transcriptional regulator
PFOHNOAK_00620 3.74e-136 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
PFOHNOAK_00621 3.17e-234 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 transcriptional
PFOHNOAK_00622 9.53e-284 rafB - - P ko:K02532 - ko00000,ko02000 LacY proton/sugar symporter
PFOHNOAK_00623 0.0 cscA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
PFOHNOAK_00625 2.17e-44 - - - - - - - -
PFOHNOAK_00626 0.0 - - - I - - - Pfam Lipase (class 3)
PFOHNOAK_00627 3.97e-16 - - - S - - - Protein of unknown function (DUF1433)
PFOHNOAK_00628 3.28e-30 - - - S - - - Protein of unknown function (DUF1433)
PFOHNOAK_00630 1.01e-120 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
PFOHNOAK_00631 7.44e-117 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PFOHNOAK_00632 4.34e-145 yyaS - - S ko:K07149 - ko00000 Membrane
PFOHNOAK_00633 1.91e-125 ywjB - - H - - - RibD C-terminal domain
PFOHNOAK_00634 0.0 pnbA - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
PFOHNOAK_00635 6.96e-100 - - - K ko:K19417 - ko00000,ko03000 transcriptional
PFOHNOAK_00636 7.89e-154 epsA - - M ko:K19420 - ko00000 biosynthesis protein
PFOHNOAK_00637 3.12e-151 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
PFOHNOAK_00638 0.0 capD - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
PFOHNOAK_00639 3.53e-277 epsD - GT4 M ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like
PFOHNOAK_00640 3.2e-205 epsE - GT2 M ko:K19423 - ko00000,ko01000,ko01003 COG0463 Glycosyltransferases involved in cell wall biogenesis
PFOHNOAK_00641 1.17e-270 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
PFOHNOAK_00642 6.95e-262 epsG - - S ko:K19419 - ko00000,ko02000 EpsG family
PFOHNOAK_00643 1.04e-245 epsH - GT2 S ko:K19425 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
PFOHNOAK_00644 3.85e-259 epsI - - GM ko:K19426 - ko00000,ko01000 pyruvyl transferase
PFOHNOAK_00645 1.73e-248 epsJ - GT2 S ko:K19427 - ko00000,ko01000 COG0463 Glycosyltransferases involved in cell wall biogenesis
PFOHNOAK_00646 0.0 epsK - - S ko:K19418 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
PFOHNOAK_00647 7.83e-140 epsL - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 COG2148 Sugar transferases involved in lipopolysaccharide synthesis
PFOHNOAK_00648 6.24e-76 epsM - - GM ko:K19429 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
PFOHNOAK_00649 2.61e-280 epsN - - E ko:K19430 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
PFOHNOAK_00650 3.71e-236 epsO - - GM ko:K19431 - ko00000,ko01000 Exopolysaccharide biosynthesis protein
PFOHNOAK_00651 4.01e-44 yvfG - - S - - - YvfG protein
PFOHNOAK_00652 1.48e-305 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
PFOHNOAK_00653 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
PFOHNOAK_00654 7.3e-155 yvfI - - K ko:K05799 - ko00000,ko03000 COG2186 Transcriptional regulators
PFOHNOAK_00655 9.81e-279 - - - EK ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko01000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
PFOHNOAK_00656 1.24e-172 lutA - - C ko:K18928 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
PFOHNOAK_00657 0.0 lutB - - C ko:K18929 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
PFOHNOAK_00658 2.79e-170 lutC - - S ko:K00782 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
PFOHNOAK_00659 1.6e-289 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
PFOHNOAK_00660 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
PFOHNOAK_00661 1.56e-194 gntR - - K - - - RpiR family transcriptional regulator
PFOHNOAK_00663 9.5e-275 yvbW - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
PFOHNOAK_00664 5.22e-203 yvbV - - EG - - - EamA-like transporter family
PFOHNOAK_00665 1.51e-200 yvbU - - K - - - Transcriptional regulator
PFOHNOAK_00667 7.57e-243 yvbT - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PFOHNOAK_00668 6.14e-258 araR - - K ko:K02103 - ko00000,ko03000 transcriptional
PFOHNOAK_00669 0.0 araE - - U ko:K02100,ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
PFOHNOAK_00671 2.95e-240 cggR - - K ko:K05311 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
PFOHNOAK_00672 2.83e-238 gapA 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
PFOHNOAK_00673 3.98e-277 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
PFOHNOAK_00674 2.58e-177 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
PFOHNOAK_00675 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and
PFOHNOAK_00676 9.69e-310 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
PFOHNOAK_00677 3.29e-301 ywaD 3.4.11.10, 3.4.11.6 - S ko:K19701 - ko00000,ko01000,ko01002 PA domain
PFOHNOAK_00678 0.0 - 1.1.1.136 - M ko:K13015 ko00520,map00520 ko00000,ko00001,ko01000,ko01005 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
PFOHNOAK_00679 1.89e-275 - 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
PFOHNOAK_00680 2.87e-218 arnA 4.2.1.46, 5.1.3.2 - M ko:K01710,ko:K01784 ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130 ko00000,ko00001,ko00002,ko01000 GDP-mannose 4,6 dehydratase
PFOHNOAK_00681 7.56e-285 - - - E - - - UDP-4-amino-4-deoxy-L-arabinose aminotransferase
PFOHNOAK_00682 2.43e-186 - - - M - - - Protein involved in cellulose biosynthesis
PFOHNOAK_00683 4.79e-184 - - - C - - - WbqC-like protein family
PFOHNOAK_00684 8.69e-160 - - - S - - - GlcNAc-PI de-N-acetylase
PFOHNOAK_00685 2.21e-225 - - - - - - - -
PFOHNOAK_00686 1.04e-267 - - - EGP - - - Major facilitator Superfamily
PFOHNOAK_00687 1.29e-105 yvbK - - K - - - acetyltransferase
PFOHNOAK_00688 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
PFOHNOAK_00689 1.08e-156 yvbI - - M - - - Membrane
PFOHNOAK_00690 4.44e-134 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
PFOHNOAK_00691 2.38e-128 - - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
PFOHNOAK_00692 2.1e-269 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
PFOHNOAK_00693 4.63e-144 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
PFOHNOAK_00694 3.25e-222 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
PFOHNOAK_00695 6.21e-141 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
PFOHNOAK_00696 3.42e-124 - - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
PFOHNOAK_00697 8.79e-263 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
PFOHNOAK_00698 3.4e-146 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
PFOHNOAK_00699 2.99e-218 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
PFOHNOAK_00700 7e-143 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
PFOHNOAK_00701 2.67e-162 spaF - - V ko:K01990,ko:K20459,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
PFOHNOAK_00702 2.72e-154 spaE - - S ko:K20491 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
PFOHNOAK_00703 9.57e-168 spaG - - S ko:K20492 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
PFOHNOAK_00704 1.29e-156 spaR - - K ko:K20488 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
PFOHNOAK_00705 0.0 spaK 2.7.13.3 - T ko:K20487 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 His Kinase A (phosphoacceptor) domain
PFOHNOAK_00706 2.97e-70 yvaP - - K - - - transcriptional
PFOHNOAK_00707 3.52e-96 yvaO - - K ko:K22299 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
PFOHNOAK_00708 9.53e-93 yvaO - - K ko:K22299 - ko00000,ko03000 transcriptional
PFOHNOAK_00709 1.64e-47 yvzC - - K - - - transcriptional
PFOHNOAK_00710 4.58e-36 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
PFOHNOAK_00711 6.92e-183 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Carboxylesterase
PFOHNOAK_00712 0.0 rnr - - K ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
PFOHNOAK_00713 4.85e-107 smpB - - O ko:K03664 - ko00000 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
PFOHNOAK_00716 1.2e-71 - - - - - - - -
PFOHNOAK_00717 1.9e-62 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
PFOHNOAK_00718 1.6e-179 yvaG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
PFOHNOAK_00719 3.98e-206 ytlI - - K ko:K21960 - ko00000,ko03000 LysR substrate binding domain
PFOHNOAK_00720 3.16e-130 ytmI - - K ko:K00680 - ko00000,ko01000 Acetyltransferase (GNAT) domain
PFOHNOAK_00721 2.8e-166 - - - ET ko:K16956,ko:K16957,ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
PFOHNOAK_00722 2.91e-187 tcyK - - M ko:K16957 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
PFOHNOAK_00723 9.92e-155 ytmL - - P ko:K16958,ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PFOHNOAK_00724 2.36e-155 - - - U ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PFOHNOAK_00725 2.48e-178 tcyN - - E ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
PFOHNOAK_00726 4.31e-233 ytmO - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PFOHNOAK_00727 1.18e-60 ytnI - - O - - - COG0695 Glutaredoxin and related proteins
PFOHNOAK_00728 0.0 ytnJ - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PFOHNOAK_00729 7.4e-181 - - - S ko:K07045 - ko00000 Amidohydrolase
PFOHNOAK_00730 5.69e-86 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
PFOHNOAK_00731 1.62e-277 - - - EGP - - - Major Facilitator Superfamily
PFOHNOAK_00732 5.5e-203 - - - K - - - Helix-turn-helix XRE-family like proteins
PFOHNOAK_00733 1.03e-153 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
PFOHNOAK_00734 1.86e-244 yvaA 1.1.1.371 - S ko:K16044 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
PFOHNOAK_00735 8.06e-64 csoR - - S ko:K21600 - ko00000,ko03000 transcriptional
PFOHNOAK_00736 3.24e-40 - - - P ko:K07213 ko04978,map04978 ko00000,ko00001 Heavy-metal-associated domain
PFOHNOAK_00737 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
PFOHNOAK_00738 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
PFOHNOAK_00739 2.15e-136 bdbD - - O - - - Thioredoxin
PFOHNOAK_00740 7.48e-96 bdbC - - O ko:K03611 - ko00000,ko03110 Required for disulfide bond formation in some proteins
PFOHNOAK_00741 1.1e-189 - - - S - - - Metallo-peptidase family M12
PFOHNOAK_00742 2.48e-127 yvgT - - S - - - membrane
PFOHNOAK_00743 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
PFOHNOAK_00744 0.0 cysJ 1.8.1.2 - P ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
PFOHNOAK_00745 0.0 cysI 1.8.1.2, 1.8.7.1 - P ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
PFOHNOAK_00746 0.0 yvgP - - P ko:K03316 - ko00000 COG0025 NhaP-type Na H and K H antiporters
PFOHNOAK_00747 1.32e-111 yvgO - - - - - - -
PFOHNOAK_00748 5.09e-200 yvgN - - S - - - reductase
PFOHNOAK_00749 1.49e-254 sagI - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
PFOHNOAK_00750 1.36e-246 sagH - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
PFOHNOAK_00751 1.31e-215 sagG - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
PFOHNOAK_00752 4.77e-250 - - - T - - - Histidine kinase
PFOHNOAK_00753 5.32e-147 yfiK - - K - - - Regulator
PFOHNOAK_00754 4.03e-127 modB - - P ko:K02018 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4149 ABC-type molybdate transport system, permease component
PFOHNOAK_00755 1.13e-177 modA - - P ko:K02020 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0725 ABC-type molybdate transport system, periplasmic component
PFOHNOAK_00756 3.32e-212 yvgK - - P ko:K07219 - ko00000 COG1910 Periplasmic molybdate-binding protein domain
PFOHNOAK_00757 0.0 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
PFOHNOAK_00758 8.3e-110 yvsG - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
PFOHNOAK_00759 4.34e-19 - - - S ko:K06427 - ko00000 Small spore protein J (Spore_SspJ)
PFOHNOAK_00760 0.0 yvsH - - E ko:K03294,ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
PFOHNOAK_00761 3.07e-160 - - - Q - - - Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
PFOHNOAK_00762 2.21e-228 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
PFOHNOAK_00763 6.64e-238 fhuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PFOHNOAK_00764 7.58e-223 fhuG - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PFOHNOAK_00765 1.02e-188 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
PFOHNOAK_00766 4.65e-86 yvrL - - S - - - Regulatory protein YrvL
PFOHNOAK_00767 7.32e-294 oxdC 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
PFOHNOAK_00768 5.37e-21 - - - S - - - YvrJ protein family
PFOHNOAK_00769 1.31e-133 yvrI - - K ko:K03093 - ko00000,ko03021 RNA polymerase
PFOHNOAK_00770 1.67e-50 - - - - - - - -
PFOHNOAK_00771 2.7e-172 yvrH - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PFOHNOAK_00772 0.0 yvrG - - T - - - Histidine kinase
PFOHNOAK_00773 3.11e-218 yvrE - - G ko:K14274 ko00040,map00040 ko00000,ko00001,ko01000 SMP-30/Gluconolaconase/LRE-like region
PFOHNOAK_00774 1.01e-179 yvrD - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
PFOHNOAK_00775 3.19e-213 yvrC - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
PFOHNOAK_00776 1.95e-226 btuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PFOHNOAK_00777 1.51e-279 yvrA 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
PFOHNOAK_00778 8.89e-131 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Adenosyltransferase
PFOHNOAK_00779 2.27e-288 yvqJ - - EGP - - - COG0477 Permeases of the major facilitator superfamily
PFOHNOAK_00780 2.21e-66 liaI - - S ko:K11619 ko02020,map02020 ko00000,ko00001,ko00002 membrane
PFOHNOAK_00781 3.63e-129 liaH - - KT ko:K03969,ko:K11620 ko02020,map02020 ko00000,ko00001,ko00002 COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
PFOHNOAK_00782 5.11e-186 liaG - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
PFOHNOAK_00783 8.92e-164 - - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
PFOHNOAK_00784 3.48e-247 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PFOHNOAK_00785 8.35e-139 vraR - - KT ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PFOHNOAK_00786 1.07e-262 gerAC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination B3/ GerAC like, C-terminal
PFOHNOAK_00787 2.07e-242 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
PFOHNOAK_00788 0.0 gerAA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
PFOHNOAK_00789 1.83e-33 - - - S - - - Protein of unknown function (DUF3970)
PFOHNOAK_00790 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
PFOHNOAK_00791 5.14e-200 yuxN - - K - - - Transcriptional regulator
PFOHNOAK_00792 4.63e-33 - - - - - - - -
PFOHNOAK_00793 0.0 cssS 2.7.13.3 - T ko:K07650 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PFOHNOAK_00794 4.5e-164 cssR - - T ko:K07770 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PFOHNOAK_00795 4.4e-304 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PFOHNOAK_00796 1.18e-102 dps2 - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
PFOHNOAK_00797 1.96e-190 yusZ - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
PFOHNOAK_00798 0.0 pepF2 - - E - - - COG1164 Oligoendopeptidase F
PFOHNOAK_00799 7.61e-60 - - - S - - - YusW-like protein
PFOHNOAK_00800 5.24e-192 yusV 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
PFOHNOAK_00801 2.15e-52 yusU - - S - - - Protein of unknown function (DUF2573)
PFOHNOAK_00802 1.83e-235 apbA 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PFOHNOAK_00803 8.35e-176 - 4.1.1.4 - Q ko:K01574 ko00072,ko00640,ko01100,map00072,map00640,map01100 ko00000,ko00001,ko00002,ko01000 Acetoacetate decarboxylase (ADC)
PFOHNOAK_00804 1.82e-198 - - - K - - - Transcriptional regulator
PFOHNOAK_00805 0.0 yusP - - P - - - Major facilitator superfamily
PFOHNOAK_00806 9.65e-92 yusO - - K - - - Iron dependent repressor, N-terminal DNA binding domain
PFOHNOAK_00807 4.46e-72 yusN - - M - - - Coat F domain
PFOHNOAK_00808 6.46e-58 - - - - - - - -
PFOHNOAK_00809 3.46e-211 fadM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
PFOHNOAK_00810 0.0 fadN 1.1.1.35 - I ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 ko00000,ko00001,ko00002,ko01000 3-hydroxyacyl-CoA dehydrogenase
PFOHNOAK_00811 7.74e-278 fadA 2.3.1.16 - I ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the thiolase family
PFOHNOAK_00812 0.0 fadE 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
PFOHNOAK_00813 7.13e-84 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
PFOHNOAK_00814 4.16e-85 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
PFOHNOAK_00815 3.1e-55 yusG - - S - - - Protein of unknown function (DUF2553)
PFOHNOAK_00816 2.17e-82 yusF - - L ko:K07476 - ko00000 COG1658 Small primase-like proteins (Toprim domain)
PFOHNOAK_00817 1.64e-72 yusE - - CO - - - Thioredoxin
PFOHNOAK_00818 5.28e-76 yusD - - S - - - SCP-2 sterol transfer family
PFOHNOAK_00819 3.71e-237 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PFOHNOAK_00820 2.08e-138 metI - - P ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2011 ABC-type metal ion transport system, permease component
PFOHNOAK_00821 5.2e-186 metQ - - P ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
PFOHNOAK_00822 2.54e-84 yurZ - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PFOHNOAK_00823 3.82e-183 sufC - - O ko:K09013 - ko00000,ko02000 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
PFOHNOAK_00824 5.01e-311 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
PFOHNOAK_00825 2.31e-298 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PFOHNOAK_00826 8.89e-101 nifU - - C ko:K04488 - ko00000 COG0822 NifU homolog involved in Fe-S cluster formation
PFOHNOAK_00827 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 FeS cluster assembly
PFOHNOAK_00828 3.07e-202 csn 3.2.1.132 - M ko:K01233 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
PFOHNOAK_00829 6.41e-32 yncE - - S - - - Protein of unknown function (DUF2691)
PFOHNOAK_00830 3.02e-254 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
PFOHNOAK_00831 3.33e-85 yurQ - - L - - - COG0322 Nuclease subunit of the excinuclease complex
PFOHNOAK_00833 6.42e-210 - - - K - - - helix_turn_helix, mercury resistance
PFOHNOAK_00834 1.35e-237 frlB - - M ko:K10708 - ko00000,ko01000 Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
PFOHNOAK_00835 5e-311 yurO - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
PFOHNOAK_00836 8.71e-202 yurN - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PFOHNOAK_00837 8.84e-210 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
PFOHNOAK_00838 1.78e-204 - 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
PFOHNOAK_00839 2.4e-172 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
PFOHNOAK_00840 1.07e-261 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
PFOHNOAK_00841 1.12e-214 bsn - - L - - - Ribonuclease
PFOHNOAK_00842 3.15e-295 pucF 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
PFOHNOAK_00843 2.71e-298 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
PFOHNOAK_00844 1.23e-273 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
PFOHNOAK_00845 2.59e-96 - - - - - - - -
PFOHNOAK_00846 0.0 pucR - - QT ko:K09684 - ko00000,ko03000 COG2508 Regulator of polyketide synthase expression
PFOHNOAK_00847 0.0 allB 3.5.2.5 - F ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
PFOHNOAK_00848 4.16e-78 - - - S - - - phosphoglycolate phosphatase activity
PFOHNOAK_00849 8.57e-216 yunF - - S - - - Protein of unknown function DUF72
PFOHNOAK_00850 2.88e-184 yunE - - S ko:K07090 - ko00000 membrane transporter protein
PFOHNOAK_00851 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
PFOHNOAK_00852 7.89e-167 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
PFOHNOAK_00853 2.36e-250 lytH - - M ko:K21472 - ko00000,ko01000,ko01002,ko01011 Peptidase, M23
PFOHNOAK_00854 3.92e-215 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
PFOHNOAK_00855 3.71e-62 yutD - - S - - - protein conserved in bacteria
PFOHNOAK_00856 3e-93 yutE - - S - - - Protein of unknown function DUF86
PFOHNOAK_00857 1.18e-179 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
PFOHNOAK_00858 1.5e-109 yutG 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
PFOHNOAK_00859 4.25e-248 yutH - - S - - - Spore coat protein
PFOHNOAK_00860 1.43e-308 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
PFOHNOAK_00861 2.3e-251 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
PFOHNOAK_00862 3.75e-214 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
PFOHNOAK_00863 0.0 yuxL 3.4.19.1 - EU ko:K01303 - ko00000,ko01000,ko01002 peptidase
PFOHNOAK_00864 1.26e-47 yutI - - O - - - COG0694 Thioredoxin-like proteins and domains
PFOHNOAK_00865 4.5e-71 yuzD - - S - - - protein conserved in bacteria
PFOHNOAK_00866 1.2e-265 yutJ 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
PFOHNOAK_00867 2.03e-51 yuzB - - S - - - Belongs to the UPF0349 family
PFOHNOAK_00868 4.26e-273 yutK - - F ko:K03317 - ko00000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PFOHNOAK_00869 2.63e-206 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PFOHNOAK_00870 1.38e-82 erpA - - S ko:K13628 - ko00000,ko03016 Belongs to the HesB IscA family
PFOHNOAK_00871 1.49e-176 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
PFOHNOAK_00873 5.3e-44 - - - S - - - Bacteriocin class IId cyclical uberolysin-like
PFOHNOAK_00875 1.08e-155 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
PFOHNOAK_00876 3.42e-92 - - - CP - - - Membrane
PFOHNOAK_00877 5.68e-40 - - - - - - - -
PFOHNOAK_00878 1.29e-234 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
PFOHNOAK_00880 1.03e-238 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 reductase
PFOHNOAK_00881 4.16e-301 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
PFOHNOAK_00882 8.54e-46 yuiB - - S - - - Putative membrane protein
PFOHNOAK_00883 2.83e-152 yuiC - - S - - - protein conserved in bacteria
PFOHNOAK_00884 2.38e-99 yuiD - - S ko:K09775 - ko00000 protein conserved in bacteria
PFOHNOAK_00885 0.0 pepA 3.4.11.1 - E ko:K01255 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
PFOHNOAK_00886 9.54e-275 yuiF - - S ko:K07084 - ko00000,ko02000 antiporter
PFOHNOAK_00887 4.35e-130 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Biotin biosynthesis protein
PFOHNOAK_00888 4.59e-155 yuiH - - S - - - Oxidoreductase molybdopterin binding domain
PFOHNOAK_00889 2.85e-208 eSD - - S ko:K07017 - ko00000 Putative esterase
PFOHNOAK_00890 5.57e-168 dhbA 1.3.1.28 - IQ ko:K00216 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
PFOHNOAK_00891 3.15e-276 dhbC 5.4.4.2 - HQ ko:K02361 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
PFOHNOAK_00892 0.0 entE 2.7.7.58, 6.3.2.14 - Q ko:K02363,ko:K04783 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 2,3-dihydroxybenzoate-AMP ligase
PFOHNOAK_00893 1.87e-218 dhbB 3.3.2.1, 6.3.2.14 - Q ko:K01252 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 Isochorismatase family
PFOHNOAK_00894 0.0 dhbF - - Q ko:K04780 ko01053,map01053 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PFOHNOAK_00895 2.24e-45 mbtH - - S ko:K05375 ko00261,ko01130,map00261,map01130 ko00000,ko00001,ko00002 MbtH-like protein
PFOHNOAK_00896 4.28e-107 yukJ - - S - - - Uncharacterized conserved protein (DUF2278)
PFOHNOAK_00897 3.64e-50 yukJ - - S - - - Uncharacterized conserved protein (DUF2278)
PFOHNOAK_00898 1.34e-259 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
PFOHNOAK_00899 2.11e-291 yukF - - QT - - - Transcriptional regulator
PFOHNOAK_00900 2.36e-61 yukE - - S - - - Belongs to the WXG100 family
PFOHNOAK_00901 9.1e-54 yukD - - S - - - WXG100 protein secretion system (Wss), protein YukD
PFOHNOAK_00902 1.2e-270 essB - - S - - - WXG100 protein secretion system (Wss), protein YukC
PFOHNOAK_00903 0.0 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
PFOHNOAK_00904 0.0 yueB - - S - - - type VII secretion protein EsaA
PFOHNOAK_00905 1.09e-99 yueC - - S - - - Family of unknown function (DUF5383)
PFOHNOAK_00906 9.7e-168 yueD 1.1.1.320 - IQ ko:K16216 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PFOHNOAK_00907 2.23e-124 yueE - - S ko:K06950 - ko00000 phosphohydrolase
PFOHNOAK_00908 1.98e-31 - - - S - - - Protein of unknown function (DUF2642)
PFOHNOAK_00909 1.54e-237 yueF - - S - - - transporter activity
PFOHNOAK_00910 9e-46 yueG - - S ko:K06299 - ko00000 Spore germination protein gerPA/gerPF
PFOHNOAK_00911 2.23e-50 yueH - - S - - - YueH-like protein
PFOHNOAK_00912 7.94e-90 yueI - - S - - - Protein of unknown function (DUF1694)
PFOHNOAK_00913 4.65e-134 pncA - - Q ko:K16788 - ko00000,ko02000 COG1335 Amidases related to nicotinamidase
PFOHNOAK_00914 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PFOHNOAK_00915 6.32e-294 yuxH - - T - - - signal transduction protein containing EAL and modified HD-GYP domains
PFOHNOAK_00916 6.01e-67 yuzC - - - - - - -
PFOHNOAK_00917 2.66e-11 - - - S - - - DegQ (SacQ) family
PFOHNOAK_00918 6.38e-118 comQ - - H ko:K02251 ko02024,map02024 ko00000,ko00001,ko02044 Polyprenyl synthetase
PFOHNOAK_00920 0.0 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PFOHNOAK_00921 8.07e-148 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PFOHNOAK_00922 9.44e-82 yuxO - - Q - - - protein, possibly involved in aromatic compounds catabolism
PFOHNOAK_00923 4.2e-79 mrpG - - P ko:K05571 - ko00000,ko02000 COG1320 Multisubunit Na H antiporter, MnhG subunit
PFOHNOAK_00924 1.1e-51 mrpF - - P ko:K05570 - ko00000,ko02000 Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
PFOHNOAK_00925 9.67e-99 mrpE - - P ko:K05569 - ko00000,ko02000 Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
PFOHNOAK_00926 0.0 mrpD - - CP ko:K05568 - ko00000,ko02000 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
PFOHNOAK_00927 1.47e-67 mrpC - - P ko:K05567 - ko00000,ko02000 Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
PFOHNOAK_00928 1.27e-89 mrpB - - P ko:K05566 - ko00000,ko02000 Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
PFOHNOAK_00929 0.0 mrpA - - CP ko:K05565 - ko00000,ko02000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
PFOHNOAK_00931 4.39e-218 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
PFOHNOAK_00932 2.72e-238 yufP - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
PFOHNOAK_00933 0.0 yufO 3.6.3.17 - S ko:K02056 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
PFOHNOAK_00934 2.36e-248 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
PFOHNOAK_00935 5.63e-163 dcuR - - T ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
PFOHNOAK_00936 0.0 malK 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
PFOHNOAK_00937 3.23e-101 yufK - - S - - - Family of unknown function (DUF5366)
PFOHNOAK_00938 2.62e-95 yuxK - - S - - - protein conserved in bacteria
PFOHNOAK_00939 0.0 pbpD 2.4.1.129, 3.4.16.4 GT51 M ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin-binding Protein
PFOHNOAK_00940 2.25e-264 yuxJ - - EGP - - - Major facilitator superfamily
PFOHNOAK_00941 2.64e-153 kapD - - L ko:K06348 - ko00000 the KinA pathway to sporulation
PFOHNOAK_00942 3.28e-87 kapB - - G ko:K06347 ko02020,map02020 ko00000,ko00001 Kinase associated protein B
PFOHNOAK_00943 8.61e-291 kinB2 2.7.13.3 - T ko:K07697 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PFOHNOAK_00944 1.3e-283 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
PFOHNOAK_00945 4.25e-55 yugE - - S - - - Domain of unknown function (DUF1871)
PFOHNOAK_00946 4.71e-199 yugF - - I - - - Hydrolase
PFOHNOAK_00947 3.75e-109 alaR - - K - - - Transcriptional regulator
PFOHNOAK_00948 6.82e-266 yugH - - E ko:K10907 - ko00000,ko01000,ko01007 Aminotransferase
PFOHNOAK_00949 1.43e-82 yugI - - J ko:K07570,ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
PFOHNOAK_00950 3.14e-46 yuzA - - S ko:K09779 - ko00000 Domain of unknown function (DUF378)
PFOHNOAK_00951 1.58e-284 yugJ - - C ko:K19955 - ko00000,ko01000 oxidoreductases, Fe-dependent alcohol dehydrogenase family
PFOHNOAK_00952 7.9e-291 yugK - - C ko:K19955 - ko00000,ko01000 Dehydrogenase
PFOHNOAK_00953 8.75e-152 ycaC - - Q - - - Isochorismatase family
PFOHNOAK_00954 5.17e-129 - - - S ko:K19784 - ko00000 NADPH-dependent FMN reductase
PFOHNOAK_00955 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
PFOHNOAK_00957 1.17e-92 yugN - - S - - - YugN-like family
PFOHNOAK_00958 2.8e-230 yugO - - P ko:K10716 - ko00000,ko02000 COG1226 Kef-type K transport systems
PFOHNOAK_00959 3.47e-35 mstX - - S - - - Membrane-integrating protein Mistic
PFOHNOAK_00960 3.06e-23 - - - - - - - -
PFOHNOAK_00961 1.67e-150 yugP - - S ko:K06973 - ko00000 Zn-dependent protease
PFOHNOAK_00962 4.67e-296 yugS - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
PFOHNOAK_00963 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
PFOHNOAK_00964 4.3e-95 yugU - - S - - - Uncharacterised protein family UPF0047
PFOHNOAK_00965 9.94e-243 npd 1.13.12.16 - S ko:K00459 ko00910,map00910 ko00000,ko00001,ko01000 COG2070 Dioxygenases related to 2-nitropropane dioxygenase
PFOHNOAK_00966 9.36e-55 - - - - - - - -
PFOHNOAK_00967 6.36e-179 tgl 2.3.2.13 - H ko:K00686 - ko00000,ko01000 Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
PFOHNOAK_00968 3.77e-315 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
PFOHNOAK_00969 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
PFOHNOAK_00970 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
PFOHNOAK_00971 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
PFOHNOAK_00972 6.95e-127 yraA 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 DJ-1/PfpI family
PFOHNOAK_00973 2.72e-237 yulF - - S ko:K22230 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
PFOHNOAK_00974 4.05e-250 yubA - - S - - - transporter activity
PFOHNOAK_00975 6.56e-187 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
PFOHNOAK_00979 8.59e-19 - - - - - - - -
PFOHNOAK_00981 2.89e-175 - - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Aspartate phosphatase response regulator
PFOHNOAK_00984 3.6e-67 yjcN - - - - - - -
PFOHNOAK_00985 4.02e-152 - - - G - - - Cupin
PFOHNOAK_00986 7.19e-279 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PFOHNOAK_00987 3.01e-190 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
PFOHNOAK_00988 1.76e-155 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
PFOHNOAK_00989 4.1e-122 yuaB - - - - - - -
PFOHNOAK_00990 9.66e-123 yuaC - - K ko:K22109 - ko00000,ko03000 Belongs to the GbsR family
PFOHNOAK_00991 0.0 gbsA 1.2.1.8 - C ko:K00130 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
PFOHNOAK_00992 1.74e-290 gbsB 1.1.1.1 - C ko:K11440 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
PFOHNOAK_00993 6.79e-141 - - - S - - - MOSC domain
PFOHNOAK_00994 2.86e-102 yuaE - - S - - - DinB superfamily
PFOHNOAK_00995 1.61e-108 yuaF - - OU - - - Membrane protein implicated in regulation of membrane protease activity
PFOHNOAK_00996 3.08e-277 yuaG - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 protein conserved in bacteria
PFOHNOAK_00997 5.96e-126 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
PFOHNOAK_00998 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
PFOHNOAK_01020 1.5e-101 ytaB - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 membrane
PFOHNOAK_01021 2.04e-167 yteA - - T - - - COG1734 DnaK suppressor protein
PFOHNOAK_01022 0.0 menF 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
PFOHNOAK_01023 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
PFOHNOAK_01024 1.07e-196 menH 4.2.99.20 - S ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
PFOHNOAK_01025 6.18e-199 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
PFOHNOAK_01026 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
PFOHNOAK_01027 2.03e-272 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
PFOHNOAK_01028 3.2e-33 - - - S - - - Domain of Unknown Function (DUF1540)
PFOHNOAK_01029 1.49e-233 ythB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG1294 Cytochrome bd-type quinol oxidase, subunit 2
PFOHNOAK_01030 4.48e-313 ythA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
PFOHNOAK_01031 7.13e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
PFOHNOAK_01032 9.31e-137 ytiB 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
PFOHNOAK_01033 6.93e-53 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
PFOHNOAK_01034 7.16e-114 luxS 4.4.1.21 - T ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
PFOHNOAK_01035 1.66e-96 ytkA - - S - - - YtkA-like
PFOHNOAK_01037 3e-98 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
PFOHNOAK_01038 3.51e-79 ytkC - - S - - - Bacteriophage holin family
PFOHNOAK_01039 1.01e-114 ytkD 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
PFOHNOAK_01040 4.35e-173 ytlD - - P ko:K02050 - ko00000,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
PFOHNOAK_01041 6.12e-184 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
PFOHNOAK_01042 1.02e-235 ytlA - - P ko:K02051 - ko00000,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
PFOHNOAK_01043 7.79e-190 ytmA - - E - - - COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
PFOHNOAK_01044 2.85e-52 ytmB - - S - - - Protein of unknown function (DUF2584)
PFOHNOAK_01045 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
PFOHNOAK_01046 7.88e-287 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PFOHNOAK_01047 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
PFOHNOAK_01048 0.0 ytnA - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
PFOHNOAK_01049 8.19e-84 ytoA - - S - - - COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
PFOHNOAK_01050 6.95e-194 ytpA 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Alpha beta hydrolase
PFOHNOAK_01051 2.35e-270 ytpB 4.2.3.130 - S ko:K16188 - ko00000,ko01000 Tetraprenyl-beta-curcumene synthase
PFOHNOAK_01052 1.67e-181 - 3.1.4.46, 5.4.2.11 - C ko:K01126,ko:K01834 ko00010,ko00260,ko00564,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00564,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 glycerophosphoryl diester phosphodiesterase
PFOHNOAK_01054 6.02e-135 ytqB - - J - - - Putative rRNA methylase
PFOHNOAK_01055 6.73e-244 ytqA - - S ko:K07139 - ko00000 Fe-S oxidoreductase
PFOHNOAK_01056 7.09e-53 ytzC - - S - - - Protein of unknown function (DUF2524)
PFOHNOAK_01058 2.68e-87 ytrA - - K ko:K07979 - ko00000,ko03000 GntR family transcriptional regulator
PFOHNOAK_01059 2.08e-207 ytrB - - P ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
PFOHNOAK_01060 4.97e-224 ytrC - - S ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
PFOHNOAK_01061 1.69e-231 - - - P ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
PFOHNOAK_01062 5.9e-178 - - - - ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
PFOHNOAK_01063 3.01e-161 ytrE - - V ko:K16920 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
PFOHNOAK_01064 3.9e-287 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
PFOHNOAK_01065 4.49e-167 graR - - T ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01504,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PFOHNOAK_01066 1.39e-233 bceS 2.7.13.3 - T ko:K11629,ko:K19077 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 His Kinase A (phosphoacceptor) domain
PFOHNOAK_01067 2.2e-172 bceA - - V ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter, ATP-binding protein
PFOHNOAK_01068 0.0 bceB - - V ko:K02004,ko:K11632,ko:K19080 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter (permease)
PFOHNOAK_01069 1.47e-157 ywaF - - S - - - Integral membrane protein
PFOHNOAK_01070 6.76e-269 yttB - - EGP - - - Major facilitator superfamily
PFOHNOAK_01071 1.32e-174 pfyP - - T - - - Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
PFOHNOAK_01072 7.19e-69 ytvB - - S - - - Protein of unknown function (DUF4257)
PFOHNOAK_01073 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
PFOHNOAK_01074 6.05e-69 ytwF - - P - - - Sulfurtransferase
PFOHNOAK_01075 1.98e-110 - - - M - - - Acetyltransferase (GNAT) domain
PFOHNOAK_01076 9.62e-317 melA 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
PFOHNOAK_01077 4.1e-184 amyC - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
PFOHNOAK_01078 5.58e-218 - - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PFOHNOAK_01079 8.91e-308 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
PFOHNOAK_01080 4.52e-238 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
PFOHNOAK_01081 2.14e-36 yteV - - S - - - Sporulation protein Cse60
PFOHNOAK_01082 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
PFOHNOAK_01083 5.3e-299 ytfP - - S ko:K07007 - ko00000 HI0933-like protein
PFOHNOAK_01084 0.0 ytgP - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
PFOHNOAK_01085 8.68e-169 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
PFOHNOAK_01086 4.46e-46 ytzE - - K - - - COG1349 Transcriptional regulators of sugar metabolism
PFOHNOAK_01087 3.14e-164 ythP - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
PFOHNOAK_01088 8.32e-275 ythQ - - U ko:K01992 - ko00000,ko00002,ko02000 Bacterial ABC transporter protein EcsB
PFOHNOAK_01089 1.17e-287 pbuO - - S ko:K06901 - ko00000,ko02000 permease
PFOHNOAK_01090 0.0 ytjP 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Dipeptidase
PFOHNOAK_01091 2.38e-222 ytkP 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
PFOHNOAK_01092 6.34e-132 ytlP 3.1.4.58 - J ko:K01975 - ko00000,ko01000,ko03016 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
PFOHNOAK_01093 3.58e-212 ytlQ - - - - - - -
PFOHNOAK_01094 3.25e-224 ytlR - - I - - - Diacylglycerol kinase catalytic domain
PFOHNOAK_01095 2.93e-199 ytmP - - M - - - Phosphotransferase
PFOHNOAK_01096 3.88e-60 ytzH - - S - - - YtzH-like protein
PFOHNOAK_01097 6.43e-160 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
PFOHNOAK_01098 5.12e-207 ytnP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
PFOHNOAK_01099 0.0 malS 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
PFOHNOAK_01100 9.96e-69 ytzB - - S - - - small secreted protein
PFOHNOAK_01101 1.76e-259 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
PFOHNOAK_01102 3.91e-100 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
PFOHNOAK_01103 5.47e-76 ytpP - - CO - - - Thioredoxin
PFOHNOAK_01104 1.69e-190 ytpQ - - S - - - Belongs to the UPF0354 family
PFOHNOAK_01105 2.08e-139 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PFOHNOAK_01106 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
PFOHNOAK_01107 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
PFOHNOAK_01108 5.38e-26 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
PFOHNOAK_01109 1.83e-30 ytxH - - S - - - COG4980 Gas vesicle protein
PFOHNOAK_01110 5.67e-56 ytxJ - - O - - - Protein of unknown function (DUF2847)
PFOHNOAK_01111 1.54e-249 aroA 2.5.1.54, 5.4.99.5 - E ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
PFOHNOAK_01112 5.91e-235 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
PFOHNOAK_01113 5.2e-186 motP - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
PFOHNOAK_01114 1.05e-155 ytxE - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
PFOHNOAK_01115 9.2e-289 acuC - - BQ ko:K04768 - ko00000 histone deacetylase
PFOHNOAK_01116 1.19e-149 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
PFOHNOAK_01117 2.84e-155 acuA - - K ko:K04766 - ko00000,ko01000 Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
PFOHNOAK_01118 0.0 acsA 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
PFOHNOAK_01119 9.91e-303 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PFOHNOAK_01120 2.07e-62 azlD - - S - - - Branched-chain amino acid transport protein (AzlD)
PFOHNOAK_01121 9.98e-161 ygaZ - - E - - - AzlC protein
PFOHNOAK_01122 1.06e-188 - - - K - - - Transcriptional regulator
PFOHNOAK_01123 1.17e-191 - - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PFOHNOAK_01124 1.55e-172 - - - E - - - GDSL-like Lipase/Acylhydrolase family
PFOHNOAK_01126 1.93e-117 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
PFOHNOAK_01128 6.9e-279 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PFOHNOAK_01130 5.41e-51 - - - S - - - SEC-C motif
PFOHNOAK_01131 1.17e-09 - - - S - - - HNH endonuclease
PFOHNOAK_01134 5.08e-09 - - - S ko:K06369 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
PFOHNOAK_01135 0.0 ywdH 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
PFOHNOAK_01136 5.75e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PFOHNOAK_01137 0.0 ytrP - - T - - - COG2199 FOG GGDEF domain
PFOHNOAK_01138 2.04e-110 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
PFOHNOAK_01139 2.41e-141 yttP - - K - - - Transcriptional regulator
PFOHNOAK_01140 1.46e-196 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 COG1387 Histidinol phosphatase and related hydrolases of the PHP family
PFOHNOAK_01141 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
PFOHNOAK_01142 1.32e-306 braB - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
PFOHNOAK_01143 1.3e-264 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
PFOHNOAK_01144 4.05e-285 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PFOHNOAK_01145 2.05e-42 sspB - - S ko:K06418,ko:K06419 - ko00000 spore protein
PFOHNOAK_01146 0.0 ytcI 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
PFOHNOAK_01147 0.0 ytcJ - - S - - - amidohydrolase
PFOHNOAK_01148 3.16e-194 nadK2 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PFOHNOAK_01149 6.39e-235 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA
PFOHNOAK_01150 2.77e-114 yteJ - - S - - - RDD family
PFOHNOAK_01151 1.26e-147 ytfI - - S - - - Protein of unknown function (DUF2953)
PFOHNOAK_01152 4.77e-100 ytfJ - - S - - - Sporulation protein YtfJ
PFOHNOAK_01153 1.12e-115 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
PFOHNOAK_01154 1.69e-231 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
PFOHNOAK_01155 1.57e-279 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PFOHNOAK_01156 3.31e-114 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
PFOHNOAK_01157 3.03e-297 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
PFOHNOAK_01158 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
PFOHNOAK_01160 1.98e-182 ytkK 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PFOHNOAK_01161 4.86e-165 ytkL - - S - - - Belongs to the UPF0173 family
PFOHNOAK_01162 1.31e-302 ytoI - - K - - - transcriptional regulator containing CBS domains
PFOHNOAK_01163 3.57e-62 ytpI - - S - - - YtpI-like protein
PFOHNOAK_01164 2.14e-231 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 COG0618 Exopolyphosphatase-related proteins
PFOHNOAK_01165 1e-31 - - - - - - - -
PFOHNOAK_01166 3.08e-113 ytrI - - - - - - -
PFOHNOAK_01167 4.94e-75 ytrH - - S - - - Sporulation protein YtrH
PFOHNOAK_01168 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
PFOHNOAK_01169 2.45e-286 ytsJ 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
PFOHNOAK_01170 3.59e-207 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PFOHNOAK_01171 1.34e-231 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
PFOHNOAK_01172 1.14e-229 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
PFOHNOAK_01173 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
PFOHNOAK_01174 3.42e-84 fxsA - - S ko:K07113 - ko00000 COG3030 Protein affecting phage T7 exclusion by the F plasmid
PFOHNOAK_01175 4.05e-247 ytvI - - S - - - sporulation integral membrane protein YtvI
PFOHNOAK_01176 5.65e-96 ytwI - - S - - - membrane
PFOHNOAK_01177 1.24e-79 yjdF3 - - S - - - Protein of unknown function (DUF2992)
PFOHNOAK_01178 1.42e-268 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
PFOHNOAK_01179 5.36e-308 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 isocitrate
PFOHNOAK_01180 1.48e-217 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible oxidation of malate to oxaloacetate
PFOHNOAK_01181 2.9e-167 phoP - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PFOHNOAK_01182 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
PFOHNOAK_01183 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PFOHNOAK_01184 4.02e-202 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
PFOHNOAK_01185 2.34e-137 ytaF - - P - - - Probably functions as a manganese efflux pump
PFOHNOAK_01186 4.17e-128 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
PFOHNOAK_01187 3.74e-204 ytbE - - S - - - reductase
PFOHNOAK_01188 3.96e-259 ytbD - - EGP ko:K19577 - ko00000,ko02000 -transporter
PFOHNOAK_01189 1.69e-89 ytcD - - K - - - Transcriptional regulator
PFOHNOAK_01190 2.1e-247 gapB 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
PFOHNOAK_01191 1.82e-88 speH 4.1.1.50 - E ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
PFOHNOAK_01192 5.95e-106 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PFOHNOAK_01193 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 Membrane attachment protein
PFOHNOAK_01194 2.87e-219 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
PFOHNOAK_01195 2.47e-137 ytxB - - S - - - SNARE associated Golgi protein
PFOHNOAK_01196 1.63e-196 ytxC - - S - - - YtxC-like family
PFOHNOAK_01197 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PFOHNOAK_01198 6.92e-192 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
PFOHNOAK_01199 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PFOHNOAK_01200 1.22e-166 lytT - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
PFOHNOAK_01201 7.85e-67 - - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 effector of murein hydrolase LrgA
PFOHNOAK_01202 2.09e-145 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
PFOHNOAK_01203 1.79e-112 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PFOHNOAK_01204 1.95e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
PFOHNOAK_01205 3.26e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PFOHNOAK_01206 5.44e-56 ysdA - - S - - - Membrane
PFOHNOAK_01207 6.58e-88 ysdB - - S - - - Sigma-w pathway protein YsdB
PFOHNOAK_01208 1.85e-263 ysdC - - G - - - COG1363 Cellulase M and related proteins
PFOHNOAK_01209 8.14e-240 abnA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
PFOHNOAK_01210 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
PFOHNOAK_01211 0.0 araB 2.7.1.16 - C ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Belongs to the ribulokinase family
PFOHNOAK_01212 3.43e-170 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
PFOHNOAK_01213 2.93e-179 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
PFOHNOAK_01214 3.19e-283 araM 1.1.1.261 - I ko:K00096 ko00564,map00564 ko00000,ko00001,ko01000 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
PFOHNOAK_01215 0.0 araN - - G ko:K17234 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
PFOHNOAK_01216 1.78e-214 araP - - P ko:K10189,ko:K10241,ko:K17235 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PFAM binding-protein-dependent transport systems inner membrane component
PFOHNOAK_01217 1.18e-191 araQ - - G ko:K17236 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport system permease
PFOHNOAK_01218 0.0 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 alpha-L-arabinofuranosidase activity
PFOHNOAK_01219 0.0 cstA - - T ko:K06200 - ko00000 Carbon starvation protein
PFOHNOAK_01220 0.0 glcF - - C ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 Glycolate oxidase
PFOHNOAK_01221 0.0 - 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD binding domain
PFOHNOAK_01222 1.1e-255 cdaR_1 - - KT ko:K02647 - ko00000,ko03000 regulator
PFOHNOAK_01223 1.07e-43 sspI - - S ko:K06426 - ko00000 Belongs to the SspI family
PFOHNOAK_01224 1.89e-172 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PFOHNOAK_01225 2.19e-249 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PFOHNOAK_01226 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PFOHNOAK_01227 7.57e-216 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PFOHNOAK_01228 2.09e-54 zapA - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
PFOHNOAK_01229 3.5e-108 yshB - - S - - - membrane protein, required for colicin V production
PFOHNOAK_01230 0.0 polX - - L ko:K02347 - ko00000,ko03400 COG1796 DNA polymerase IV (family X)
PFOHNOAK_01231 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
PFOHNOAK_01232 3.09e-88 yshE - - S ko:K08989 - ko00000 membrane
PFOHNOAK_01233 1.61e-150 ywbB - - S - - - Protein of unknown function (DUF2711)
PFOHNOAK_01234 0.0 lcfA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
PFOHNOAK_01235 1.78e-133 fadR - - K ko:K13770 - ko00000,ko03000 Transcriptional regulator
PFOHNOAK_01236 4.1e-177 fadB 4.2.1.17 - I ko:K13767 ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the enoyl-CoA hydratase isomerase family
PFOHNOAK_01237 1.43e-176 etfB - - C ko:K03521 - ko00000 Electron transfer flavoprotein
PFOHNOAK_01238 1.18e-225 etfA - - C ko:K03522 - ko00000,ko04147 Electron transfer flavoprotein
PFOHNOAK_01239 0.0 xsa 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
PFOHNOAK_01240 1.6e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
PFOHNOAK_01241 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
PFOHNOAK_01242 1.01e-273 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
PFOHNOAK_01243 7.02e-103 yslB - - S - - - Protein of unknown function (DUF2507)
PFOHNOAK_01244 2.73e-140 sdhC - - C ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 succinate dehydrogenase
PFOHNOAK_01245 0.0 sdhA 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
PFOHNOAK_01246 4.34e-189 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
PFOHNOAK_01247 1.8e-99 ysmA - - S ko:K07107 - ko00000,ko01000 thioesterase
PFOHNOAK_01248 6.32e-42 gerE - - K ko:K01994 - ko00000,ko03000 Transcriptional regulator
PFOHNOAK_01249 3.77e-97 ysmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
PFOHNOAK_01250 1.15e-196 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
PFOHNOAK_01251 2.12e-253 gerM - - S ko:K06298 - ko00000 COG5401 Spore germination protein
PFOHNOAK_01252 4.12e-170 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
PFOHNOAK_01253 4.55e-131 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PFOHNOAK_01254 6.72e-118 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
PFOHNOAK_01259 0.0 ilvB 2.2.1.6 - E ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
PFOHNOAK_01260 2.06e-109 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
PFOHNOAK_01261 2.75e-244 ilvC 1.1.1.86 - EH ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
PFOHNOAK_01262 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PFOHNOAK_01263 2.48e-254 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
PFOHNOAK_01264 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PFOHNOAK_01265 3.77e-150 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PFOHNOAK_01266 9.14e-239 ysoA - - H - - - Tetratricopeptide repeat
PFOHNOAK_01267 2.18e-287 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
PFOHNOAK_01268 3.83e-295 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PFOHNOAK_01269 0.0 lonB 3.4.21.53 - LO ko:K04076 - ko00000,ko01000,ko01002 Belongs to the peptidase S16 family
PFOHNOAK_01270 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
PFOHNOAK_01271 3.1e-138 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
PFOHNOAK_01272 3.93e-114 ysxD - - - - - - -
PFOHNOAK_01273 3.56e-314 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
PFOHNOAK_01274 2.67e-186 hemX - - O ko:K02497 - ko00000 cytochrome C
PFOHNOAK_01275 1.05e-222 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
PFOHNOAK_01276 6.6e-181 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
PFOHNOAK_01277 1.02e-235 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the ALAD family
PFOHNOAK_01278 4.63e-312 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
PFOHNOAK_01279 2.53e-294 spoVID - - M ko:K06417 - ko00000 stage VI sporulation protein D
PFOHNOAK_01280 1.89e-251 ysxE - - S - - - A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
PFOHNOAK_01281 1.53e-35 - - - - - - - -
PFOHNOAK_01282 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
PFOHNOAK_01283 5.14e-305 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
PFOHNOAK_01284 4.26e-170 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
PFOHNOAK_01285 1.04e-207 spoIIB - - S ko:K06380 - ko00000 Sporulation related domain
PFOHNOAK_01286 1.53e-126 maf - - D ko:K06287 - ko00000 septum formation protein Maf
PFOHNOAK_01287 7.15e-164 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
PFOHNOAK_01288 1.06e-234 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein MreB
PFOHNOAK_01289 2.51e-201 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
PFOHNOAK_01290 1.76e-110 mreD - - M ko:K03571 - ko00000,ko03036 shape-determining protein
PFOHNOAK_01291 6.85e-155 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
PFOHNOAK_01292 1.61e-183 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
PFOHNOAK_01293 1.14e-187 spoIVFA - - M ko:K06401 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
PFOHNOAK_01294 4.89e-204 spoIVFB - - S ko:K06402 - ko00000,ko01000,ko01002 Stage IV sporulation protein
PFOHNOAK_01295 1.28e-65 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
PFOHNOAK_01296 1.42e-74 ysxB - - J ko:K07584 - ko00000 ribosomal protein
PFOHNOAK_01297 7.74e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
PFOHNOAK_01298 6.78e-136 spo0B - - T ko:K06375 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Sporulation initiation phospho-transferase B, C-terminal
PFOHNOAK_01299 2.37e-309 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PFOHNOAK_01300 2.42e-94 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
PFOHNOAK_01301 8.16e-206 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
PFOHNOAK_01302 1.38e-120 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
PFOHNOAK_01303 1.35e-283 nifS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
PFOHNOAK_01304 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
PFOHNOAK_01305 4.13e-193 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
PFOHNOAK_01306 2.02e-270 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
PFOHNOAK_01307 1.48e-247 safA - - M ko:K06370 - ko00000 spore coat assembly protein SafA
PFOHNOAK_01308 2.72e-62 - - - S ko:K06345 - ko00000 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
PFOHNOAK_01310 1.41e-119 bofC - - S ko:K06318 - ko00000 BofC C-terminal domain
PFOHNOAK_01311 8.13e-137 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
PFOHNOAK_01312 3.57e-236 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
PFOHNOAK_01313 9.76e-29 yrzS - - S - - - Protein of unknown function (DUF2905)
PFOHNOAK_01314 5.79e-246 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
PFOHNOAK_01315 8.2e-293 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
PFOHNOAK_01316 1.03e-50 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit YajC
PFOHNOAK_01317 9.08e-81 yrzE - - S - - - Protein of unknown function (DUF3792)
PFOHNOAK_01318 2.03e-143 yrbG - - S - - - membrane
PFOHNOAK_01319 0.0 spoVB - - S ko:K06409 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
PFOHNOAK_01320 4.04e-67 yrzD - - S - - - Post-transcriptional regulator
PFOHNOAK_01321 0.0 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PFOHNOAK_01322 8.88e-112 trkA1 - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
PFOHNOAK_01323 7.78e-63 yrvD - - S - - - Lipopolysaccharide assembly protein A domain
PFOHNOAK_01324 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
PFOHNOAK_01325 5.1e-118 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PFOHNOAK_01326 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PFOHNOAK_01327 4.95e-98 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
PFOHNOAK_01328 0.0 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG3103 SH3 domain protein
PFOHNOAK_01331 5.8e-308 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
PFOHNOAK_01332 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
PFOHNOAK_01333 1.96e-177 yrvM - - H ko:K22132 - ko00000,ko03016 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
PFOHNOAK_01334 3.74e-303 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
PFOHNOAK_01335 9.19e-84 cymR - - K ko:K17472 - ko00000,ko03000 Transcriptional regulator
PFOHNOAK_01336 2.98e-269 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
PFOHNOAK_01337 2.4e-280 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
PFOHNOAK_01338 1.12e-23 yrrB - - S - - - COG0457 FOG TPR repeat
PFOHNOAK_01339 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
PFOHNOAK_01340 1.69e-105 yrrD - - S - - - protein conserved in bacteria
PFOHNOAK_01341 8.4e-42 yrzR - - - - - - -
PFOHNOAK_01342 6.52e-13 - - - S - - - Protein of unknown function (DUF3918)
PFOHNOAK_01343 3.1e-138 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
PFOHNOAK_01344 3.24e-139 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
PFOHNOAK_01345 1.82e-188 glnH - - ET ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
PFOHNOAK_01346 2.12e-166 glnQ - - E ko:K09972,ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
PFOHNOAK_01347 2.58e-234 yrrI - - S - - - AI-2E family transporter
PFOHNOAK_01348 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PFOHNOAK_01349 1.29e-54 yrzL - - S - - - Belongs to the UPF0297 family
PFOHNOAK_01350 2.72e-93 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PFOHNOAK_01351 7.2e-61 yrzB - - S - - - Belongs to the UPF0473 family
PFOHNOAK_01352 4.48e-256 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PFOHNOAK_01353 3.29e-153 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-methyltransferase
PFOHNOAK_01354 6.3e-222 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
PFOHNOAK_01355 1.09e-311 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 COG0826 Collagenase and related proteases
PFOHNOAK_01356 2.61e-147 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
PFOHNOAK_01357 1.62e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PFOHNOAK_01358 0.0 pbpI - - M ko:K21468 - ko00000,ko01011 Penicillin-binding Protein
PFOHNOAK_01359 3.56e-124 yrrS - - S - - - Protein of unknown function (DUF1510)
PFOHNOAK_01360 1.78e-38 yrzA - - S - - - Protein of unknown function (DUF2536)
PFOHNOAK_01361 8.11e-152 yrrT - - Q ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Could be a S-adenosyl-L-methionine-dependent methyltransferase
PFOHNOAK_01362 5.64e-161 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PFOHNOAK_01363 1.61e-218 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Cysteine synthase
PFOHNOAK_01364 1.21e-266 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
PFOHNOAK_01365 5.51e-46 yrhC - - S - - - YrhC-like protein
PFOHNOAK_01366 4.76e-106 yrhD - - S - - - Protein of unknown function (DUF1641)
PFOHNOAK_01367 0.0 yrhE 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase, alpha subunit
PFOHNOAK_01368 1.48e-78 yrhF - - S - - - Uncharacterized conserved protein (DUF2294)
PFOHNOAK_01369 3.96e-183 yrhG - - P ko:K21993 - ko00000,ko02000 Formate nitrite
PFOHNOAK_01370 2.37e-07 - - - S - - - Probable sporulation protein (Bac_small_yrzI)
PFOHNOAK_01371 2.12e-119 yrhH - - Q - - - methyltransferase
PFOHNOAK_01372 7.91e-129 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
PFOHNOAK_01373 0.0 yrhJ 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
PFOHNOAK_01374 3.09e-269 yybF1 - - EGP ko:K08224 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
PFOHNOAK_01375 8.84e-210 yybE - - K - - - Transcriptional regulator
PFOHNOAK_01376 1.22e-102 ebsC - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PFOHNOAK_01377 3.33e-229 romA - - S - - - Beta-lactamase superfamily domain
PFOHNOAK_01378 0.0 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 transcriptional antiterminator
PFOHNOAK_01379 0.0 manP 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
PFOHNOAK_01380 2.23e-234 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
PFOHNOAK_01381 2.38e-167 - - - K - - - Helix-turn-helix domain, rpiR family
PFOHNOAK_01382 1.13e-184 supH - - S - - - Sucrose-6F-phosphate phosphohydrolase
PFOHNOAK_01383 3.82e-186 supH - - S - - - hydrolase
PFOHNOAK_01385 1.08e-117 - - - S - - - DinB family
PFOHNOAK_01386 3.52e-106 - - - K ko:K19273 - ko00000,ko01000,ko01504 Acetyltransferase (GNAT) domain
PFOHNOAK_01387 7.94e-31 - - - - - - - -
PFOHNOAK_01390 1.04e-74 - - - S - - - Abortive infection C-terminus
PFOHNOAK_01395 7.19e-152 - - - L ko:K21487 - ko00000,ko01000,ko02048 nucleic acid phosphodiester bond hydrolysis
PFOHNOAK_01396 4.37e-74 - - - S - - - SMI1-KNR4 cell-wall
PFOHNOAK_01398 1.53e-279 tetL - - EGP ko:K08168 - ko00000,ko00002,ko01504,ko02000 COG0477 Permeases of the major facilitator superfamily
PFOHNOAK_01399 1.41e-30 - - - K - - - acetyltransferase
PFOHNOAK_01400 8.74e-125 yqaC - - F - - - adenylate kinase activity
PFOHNOAK_01401 7.92e-189 ydeE - - K ko:K13653 - ko00000,ko03000 AraC family transcriptional regulator
PFOHNOAK_01402 5.47e-120 - - - K - - - Transcriptional regulator PadR-like family
PFOHNOAK_01403 1.25e-202 - - - S - - - Carbohydrate esterase, sialic acid-specific acetylesterase
PFOHNOAK_01404 6.78e-160 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PFOHNOAK_01405 3.73e-269 - - - EGP - - - Transmembrane secretion effector
PFOHNOAK_01406 6.87e-137 yqeD - - S - - - SNARE associated Golgi protein
PFOHNOAK_01407 6.38e-178 pdaC 3.5.1.104 - G ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
PFOHNOAK_01408 1.2e-176 yqeF - - E - - - GDSL-like Lipase/Acylhydrolase
PFOHNOAK_01410 3.19e-122 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
PFOHNOAK_01411 1.31e-270 yqeH - - S ko:K06948 - ko00000,ko03009 In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
PFOHNOAK_01412 1.7e-200 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PFOHNOAK_01413 1.81e-60 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein containing KH domain, possibly ribosomal protein
PFOHNOAK_01414 6.82e-139 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PFOHNOAK_01415 1.76e-130 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
PFOHNOAK_01416 9.39e-80 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
PFOHNOAK_01417 4.86e-178 yqeM - - Q - - - Methyltransferase
PFOHNOAK_01418 1.39e-191 comER - - E ko:K02239 - ko00000,ko00002,ko02044 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PFOHNOAK_01419 1.63e-133 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
PFOHNOAK_01420 3.79e-136 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
PFOHNOAK_01421 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
PFOHNOAK_01422 7.42e-232 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
PFOHNOAK_01423 1.91e-47 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
PFOHNOAK_01424 1.02e-259 gpr 3.4.24.78 - C ko:K06012 - ko00000,ko01000,ko01002 Initiates the rapid degradation of small, acid-soluble proteins during spore germination
PFOHNOAK_01425 2.5e-277 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
PFOHNOAK_01426 3.5e-70 yqxA - - S - - - Protein of unknown function (DUF3679)
PFOHNOAK_01427 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
PFOHNOAK_01428 1.96e-274 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
PFOHNOAK_01429 5.74e-240 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
PFOHNOAK_01430 5.18e-110 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PFOHNOAK_01431 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
PFOHNOAK_01432 4.93e-266 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
PFOHNOAK_01433 6.31e-223 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
PFOHNOAK_01434 1.44e-180 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
PFOHNOAK_01435 0.0 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 ribosomal protein S12 methylthiotransferase
PFOHNOAK_01436 9.26e-200 yqeW - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
PFOHNOAK_01437 1.03e-26 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
PFOHNOAK_01438 6.44e-90 yqeY - - S ko:K09117 - ko00000 Yqey-like protein
PFOHNOAK_01439 3.83e-295 yqeZ - - O ko:K07403 - ko00000 COG1030 Membrane-bound serine protease (ClpP class)
PFOHNOAK_01440 1.3e-174 yqfA - - S - - - UPF0365 protein
PFOHNOAK_01441 2.85e-82 yqfB - - - - - - -
PFOHNOAK_01442 3.57e-61 yqfC - - S - - - sporulation protein YqfC
PFOHNOAK_01443 3.72e-282 yqfD - - S ko:K06438 - ko00000 Stage IV sporulation
PFOHNOAK_01444 7.08e-224 phoH - - T ko:K06217 - ko00000 Phosphate starvation-inducible protein PhoH
PFOHNOAK_01445 0.0 yqfF - - S ko:K07037 - ko00000 membrane-associated HD superfamily hydrolase
PFOHNOAK_01446 1.44e-104 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PFOHNOAK_01447 5.28e-83 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
PFOHNOAK_01448 1.92e-92 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
PFOHNOAK_01449 8.2e-214 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PFOHNOAK_01450 6e-24 - - - S - - - YqzL-like protein
PFOHNOAK_01451 5.05e-185 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
PFOHNOAK_01452 5.19e-223 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
PFOHNOAK_01453 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
PFOHNOAK_01454 5.89e-145 ccpN - - K - - - CBS domain
PFOHNOAK_01455 5.46e-192 yqfL 2.7.11.33, 2.7.4.28 - S ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
PFOHNOAK_01456 1.36e-112 yqxD - - S ko:K09768 - ko00000 Belongs to the UPF0178 family
PFOHNOAK_01457 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
PFOHNOAK_01458 3.97e-255 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
PFOHNOAK_01459 9.68e-83 cccA - - C ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
PFOHNOAK_01460 6e-162 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
PFOHNOAK_01461 1.72e-265 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PFOHNOAK_01462 5.01e-226 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
PFOHNOAK_01463 4.54e-86 yqfQ - - S - - - YqfQ-like protein
PFOHNOAK_01464 1.05e-308 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
PFOHNOAK_01465 2.86e-212 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
PFOHNOAK_01466 8.63e-49 yqfT - - S - - - Protein of unknown function (DUF2624)
PFOHNOAK_01467 6.35e-198 yqfU - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
PFOHNOAK_01468 2.25e-100 zur - - P ko:K02076 - ko00000,ko03000 Belongs to the Fur family
PFOHNOAK_01469 7.06e-143 yqfW - - S ko:K05967 - ko00000 Belongs to the 5'(3')-deoxyribonucleotidase family
PFOHNOAK_01470 3.34e-80 yqfX - - S - - - membrane
PFOHNOAK_01471 1.97e-256 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
PFOHNOAK_01472 3.05e-63 yqfZ - - M ko:K06417 - ko00000 LysM domain
PFOHNOAK_01473 2.97e-165 yqgB - - S - - - Protein of unknown function (DUF1189)
PFOHNOAK_01474 2.27e-98 yqgC - - S ko:K09793 - ko00000 protein conserved in bacteria
PFOHNOAK_01475 4.22e-148 sodA 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
PFOHNOAK_01476 9.63e-289 yqgE - - EGP ko:K08222 - ko00000,ko02000 Major facilitator superfamily
PFOHNOAK_01477 0.0 pbpA - - M ko:K21465,ko:K21466 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
PFOHNOAK_01478 9.5e-208 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
PFOHNOAK_01479 2.48e-203 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
PFOHNOAK_01480 3.26e-196 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
PFOHNOAK_01481 4.62e-183 pstBA 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PFOHNOAK_01482 6.64e-188 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PFOHNOAK_01483 4.15e-98 yqzC - - S - - - Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PFOHNOAK_01484 3.42e-68 yqzD - - - - - - -
PFOHNOAK_01485 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
PFOHNOAK_01486 6.07e-126 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PFOHNOAK_01487 3.79e-11 yqgO - - - - - - -
PFOHNOAK_01488 1.77e-299 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter
PFOHNOAK_01489 2.05e-228 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
PFOHNOAK_01490 3.67e-277 yqgT 3.4.19.11 - E ko:K01308 - ko00000,ko01000,ko01002 Gamma-D-glutamyl-L-diamino acid endopeptidase
PFOHNOAK_01491 2.11e-253 yqgU - - - - - - -
PFOHNOAK_01492 2.99e-65 dglA - - S - - - Thiamine-binding protein
PFOHNOAK_01493 2.16e-28 yqgW - - S - - - Protein of unknown function (DUF2759)
PFOHNOAK_01494 2.84e-156 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
PFOHNOAK_01495 4.19e-50 yqgY - - S - - - Protein of unknown function (DUF2626)
PFOHNOAK_01496 1.15e-86 yqgZ 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
PFOHNOAK_01498 1.68e-189 yqhA - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
PFOHNOAK_01499 7.58e-304 yqhB - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
PFOHNOAK_01500 6.43e-239 yqxL - - P - - - Mg2 transporter protein
PFOHNOAK_01501 9.05e-257 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PFOHNOAK_01502 1.09e-231 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 COG1459 Type II secretory pathway, component PulF
PFOHNOAK_01503 2.41e-55 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
PFOHNOAK_01504 1.32e-92 - - - NU ko:K02246,ko:K08084 - ko00000,ko00002,ko02044 Tfp pilus assembly protein FimT
PFOHNOAK_01505 2.21e-26 comGE - - - ko:K02247 - ko00000,ko00002,ko02044 -
PFOHNOAK_01506 2.22e-85 comGF - - U ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
PFOHNOAK_01507 9.51e-81 - - - S ko:K02249 - ko00000,ko00002,ko02044 ComG operon protein 7
PFOHNOAK_01508 2e-36 yqzE - - S - - - YqzE-like protein
PFOHNOAK_01509 1.97e-70 yqzG - - S - - - Protein of unknown function (DUF3889)
PFOHNOAK_01510 1.34e-155 yqxM - - - ko:K19433 - ko00000 -
PFOHNOAK_01511 1.33e-102 sipW 3.4.21.89 - U ko:K13280 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase
PFOHNOAK_01512 6.08e-180 tasA_1 - - S ko:K06336 - ko00000,ko01002 Cell division protein FtsN
PFOHNOAK_01513 2.75e-72 sinR - - K ko:K19449 - ko00000,ko03000 transcriptional
PFOHNOAK_01514 2.31e-32 sinI - - S ko:K06372 - ko00000 Anti-repressor SinI
PFOHNOAK_01515 3.57e-194 yqhG - - S - - - Bacterial protein YqhG of unknown function
PFOHNOAK_01516 0.0 yqhH - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
PFOHNOAK_01517 1.35e-263 gcvT 2.1.2.10 - E ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
PFOHNOAK_01518 0.0 gcvPA 1.4.4.2 - E ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PFOHNOAK_01519 0.0 gcvPB 1.4.4.2 - E ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PFOHNOAK_01520 3.18e-84 yqhL - - P - - - COG0607 Rhodanese-related sulfurtransferase
PFOHNOAK_01521 1.58e-204 lipM 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
PFOHNOAK_01522 5.64e-97 mntR - - K ko:K03709 - ko00000,ko03000 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
PFOHNOAK_01523 2.85e-209 yqhO - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
PFOHNOAK_01524 1.54e-82 yqhP - - - - - - -
PFOHNOAK_01525 7.33e-221 yqhQ - - S - - - Protein of unknown function (DUF1385)
PFOHNOAK_01526 1.82e-116 yqhR - - S - - - Conserved membrane protein YqhR
PFOHNOAK_01527 6.04e-249 yqhT 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
PFOHNOAK_01528 6.82e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PFOHNOAK_01529 9.89e-50 yqhV - - S - - - Protein of unknown function (DUF2619)
PFOHNOAK_01530 4.43e-221 spoIIIAA - - S ko:K06390 - ko00000 stage III sporulation protein AA
PFOHNOAK_01531 1.91e-109 spoIIIAB - - S ko:K06391 - ko00000 Stage III sporulation protein
PFOHNOAK_01532 1.63e-39 spoIIIAC - - S ko:K06392 - ko00000 stage III sporulation protein AC
PFOHNOAK_01533 3.72e-55 spoIIIAD - - S ko:K06393 - ko00000 Stage III sporulation protein AD
PFOHNOAK_01534 5.23e-261 spoIIIAE - - S ko:K06394 - ko00000 stage III sporulation protein AE
PFOHNOAK_01535 3.01e-130 spoIIIAF - - S ko:K06395 - ko00000 Stage III sporulation protein AF (Spore_III_AF)
PFOHNOAK_01536 1.12e-146 spoIIIAG - - S ko:K06396 - ko00000 stage III sporulation protein AG
PFOHNOAK_01537 2.74e-94 spoIIIAH - - S ko:K06397 - ko00000 SpoIIIAH-like protein
PFOHNOAK_01538 1.63e-86 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
PFOHNOAK_01539 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
PFOHNOAK_01540 1.36e-87 yqhY - - S - - - protein conserved in bacteria
PFOHNOAK_01541 2.58e-85 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PFOHNOAK_01542 1.24e-199 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PFOHNOAK_01543 1.43e-310 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PFOHNOAK_01544 2.67e-52 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PFOHNOAK_01545 1.83e-203 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
PFOHNOAK_01546 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PFOHNOAK_01547 8.39e-197 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 rRNA methylase
PFOHNOAK_01548 4.38e-102 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
PFOHNOAK_01549 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
PFOHNOAK_01550 8.85e-304 spoIVB 3.4.21.116 - M ko:K06399 - ko00000,ko01000,ko01002 Stage IV sporulation protein B
PFOHNOAK_01551 6.11e-187 spo0A - - KT ko:K07699 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
PFOHNOAK_01552 1.13e-271 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PFOHNOAK_01555 9.27e-272 yqiG - - C - - - COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
PFOHNOAK_01557 1.15e-145 - - - K - - - Protein of unknown function (DUF1232)
PFOHNOAK_01558 1.32e-129 - - - P - - - Probably functions as a manganese efflux pump
PFOHNOAK_01560 1.97e-136 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Cell wall hydrolase autolysin
PFOHNOAK_01561 1.5e-172 yqiK 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
PFOHNOAK_01562 3.78e-270 mmgA 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
PFOHNOAK_01563 2.51e-199 mmgB 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
PFOHNOAK_01564 1.69e-258 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
PFOHNOAK_01565 2.71e-258 mmgD 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
PFOHNOAK_01566 0.0 prpD 4.2.1.79 - S ko:K01720 ko00640,map00640 ko00000,ko00001,ko01000 2-methylcitrate dehydratase
PFOHNOAK_01567 1.63e-204 prpB 4.1.3.30, 5.4.2.9 - G ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
PFOHNOAK_01568 6.25e-47 yqzF - - S - - - Protein of unknown function (DUF2627)
PFOHNOAK_01569 0.0 bkdR - - KT - - - Transcriptional regulator
PFOHNOAK_01570 9.24e-193 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 phosphate butyryltransferase
PFOHNOAK_01571 1.58e-261 ldh 1.4.1.9 - E ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
PFOHNOAK_01572 1.57e-259 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Belongs to the acetokinase family
PFOHNOAK_01573 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
PFOHNOAK_01574 1.07e-219 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
PFOHNOAK_01575 1.7e-235 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
PFOHNOAK_01576 2.42e-282 bkdB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
PFOHNOAK_01577 1.22e-218 bmrU - - I - - - COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
PFOHNOAK_01578 1.68e-99 yqiW - - S - - - Belongs to the UPF0403 family
PFOHNOAK_01579 1.37e-173 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
PFOHNOAK_01580 1.04e-141 artQ - - E ko:K02029 - ko00000,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
PFOHNOAK_01581 1.74e-164 artM 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
PFOHNOAK_01582 3.22e-219 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
PFOHNOAK_01583 3.7e-123 yqjB - - S - - - protein conserved in bacteria
PFOHNOAK_01585 1.89e-95 mce 5.1.99.1 - E ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0346 Lactoylglutathione lyase and related lyases
PFOHNOAK_01586 0.0 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
PFOHNOAK_01587 1.06e-258 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 COG2195 Di- and tripeptidases
PFOHNOAK_01588 1.18e-190 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PFOHNOAK_01589 1.3e-34 yqzJ - - - - - - -
PFOHNOAK_01590 9.1e-300 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PFOHNOAK_01591 0.0 gnd 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
PFOHNOAK_01592 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PFOHNOAK_01593 7.61e-218 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
PFOHNOAK_01594 1.95e-169 yqjL - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
PFOHNOAK_01595 1.27e-247 namA 1.6.99.1 - C ko:K00354 - ko00000,ko01000 Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
PFOHNOAK_01596 8.46e-20 - - - S - - - GlpM protein
PFOHNOAK_01597 5.96e-207 - - - K - - - LysR substrate binding domain
PFOHNOAK_01598 4.32e-122 nusG1 - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
PFOHNOAK_01599 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
PFOHNOAK_01602 4.54e-313 - 6.1.3.1, 6.2.1.3, 6.2.1.34 - IQ ko:K00666,ko:K01897,ko:K12508,ko:K22319 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
PFOHNOAK_01603 1.54e-165 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
PFOHNOAK_01604 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
PFOHNOAK_01605 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
PFOHNOAK_01606 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
PFOHNOAK_01607 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
PFOHNOAK_01608 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
PFOHNOAK_01609 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
PFOHNOAK_01610 0.0 - 1.6.5.5 - C ko:K00344 - ko00000,ko01000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
PFOHNOAK_01611 1.15e-280 - 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
PFOHNOAK_01612 5.89e-304 - 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
PFOHNOAK_01613 1.38e-174 - - - I ko:K15313 - ko00000,ko01008 Belongs to the enoyl-CoA hydratase isomerase family
PFOHNOAK_01614 5.8e-185 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PFOHNOAK_01615 1.08e-220 yqjP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
PFOHNOAK_01616 1.38e-179 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
PFOHNOAK_01617 0.0 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
PFOHNOAK_01618 6.33e-227 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
PFOHNOAK_01619 1.81e-94 yqjT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PFOHNOAK_01621 8.33e-238 yueF - - S - - - transporter activity
PFOHNOAK_01623 1.26e-73 - - - S - - - YolD-like protein
PFOHNOAK_01624 7.74e-298 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PFOHNOAK_01625 1.15e-114 yqjY - - K ko:K06977 - ko00000 acetyltransferase
PFOHNOAK_01626 3.46e-80 yqjZ - - S - - - enzyme involved in biosynthesis of extracellular polysaccharides
PFOHNOAK_01627 3.26e-220 yqkA - - K - - - GrpB protein
PFOHNOAK_01628 5.4e-80 yqkB - - S - - - Belongs to the HesB IscA family
PFOHNOAK_01629 4.57e-53 yqkC - - S - - - Protein of unknown function (DUF2552)
PFOHNOAK_01630 9.62e-225 yqkD - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
PFOHNOAK_01631 5.53e-09 yqkE - - S - - - Protein of unknown function (DUF3886)
PFOHNOAK_01632 2.97e-214 yqkF - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
PFOHNOAK_01633 2.01e-10 - - - S - - - Protein of unknown function (DUF3936)
PFOHNOAK_01634 6.03e-122 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
PFOHNOAK_01635 5.91e-280 yqxK - - L - - - DNA helicase
PFOHNOAK_01636 4e-76 ansR - - K - - - Transcriptional regulator
PFOHNOAK_01637 2.63e-240 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase
PFOHNOAK_01638 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Aspartate ammonia-lyase
PFOHNOAK_01639 1.19e-311 mleN - - C ko:K03315 - ko00000,ko02000 Na H antiporter
PFOHNOAK_01640 2.38e-309 mleA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
PFOHNOAK_01641 1.96e-30 - - - - - - - -
PFOHNOAK_01642 7.29e-46 yqkK - - - - - - -
PFOHNOAK_01644 5.01e-142 spoIIM - - S ko:K06384 - ko00000 Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
PFOHNOAK_01645 4.56e-104 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
PFOHNOAK_01646 9.51e-51 - - - S - - - Protein of unknown function (DUF4227)
PFOHNOAK_01647 1.59e-213 xerD - - L ko:K04763 - ko00000,ko03036 recombinase XerD
PFOHNOAK_01648 9.63e-292 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
PFOHNOAK_01649 7.14e-189 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
PFOHNOAK_01650 3.52e-273 dacF 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
PFOHNOAK_01651 4e-76 spoIIAA - - T ko:K06378 - ko00000 Belongs to the anti-sigma-factor antagonist family
PFOHNOAK_01652 4.77e-100 spoIIAB 2.7.11.1 - F ko:K06379 - ko00000,ko01000 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
PFOHNOAK_01653 6.81e-174 sigF - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PFOHNOAK_01654 6.68e-143 spoVAA - - S ko:K06403 - ko00000 Stage V sporulation protein AA
PFOHNOAK_01655 1.43e-78 spoVAB - - S ko:K06404 - ko00000 Stage V sporulation protein AB
PFOHNOAK_01656 9.92e-104 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
PFOHNOAK_01657 5.53e-242 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
PFOHNOAK_01658 2.15e-75 spoVAEB - - S ko:K06407 - ko00000 stage V sporulation protein
PFOHNOAK_01659 7.55e-142 - - - S ko:K06407 - ko00000 stage V sporulation protein
PFOHNOAK_01660 0.0 spoVAF - - EG ko:K06408 - ko00000 Stage V sporulation protein AF
PFOHNOAK_01661 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
PFOHNOAK_01662 3.65e-198 ypuA - - S - - - Secreted protein
PFOHNOAK_01663 4.12e-104 ppiB 5.2.1.8 - O ko:K01802,ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PFOHNOAK_01664 5.56e-105 ccdC1 - - O - - - Protein of unknown function (DUF1453)
PFOHNOAK_01665 6.56e-131 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
PFOHNOAK_01666 2.01e-70 ypuD - - - - - - -
PFOHNOAK_01667 3.09e-267 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PFOHNOAK_01668 8.02e-144 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
PFOHNOAK_01669 1.8e-291 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PFOHNOAK_01670 6.92e-106 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
PFOHNOAK_01671 2.74e-84 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PFOHNOAK_01672 1.99e-121 ypuF - - S ko:K09763 - ko00000 Domain of unknown function (DUF309)
PFOHNOAK_01674 9.53e-163 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
PFOHNOAK_01675 7.84e-133 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PFOHNOAK_01676 6.14e-122 ypuI - - S - - - Protein of unknown function (DUF3907)
PFOHNOAK_01677 1.14e-275 dacB 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
PFOHNOAK_01678 3.75e-135 spmA - - S ko:K06373 - ko00000 Spore maturation protein
PFOHNOAK_01679 8.99e-116 spmB - - S ko:K06374 - ko00000 Spore maturation protein
PFOHNOAK_01680 1.49e-167 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
PFOHNOAK_01681 4.31e-128 resA - - CO - - - Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
PFOHNOAK_01682 0.0 resB - - O ko:K07399 - ko00000 COG1333 ResB protein required for cytochrome c biosynthesis
PFOHNOAK_01683 6.24e-252 resC - - O - - - 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
PFOHNOAK_01684 9.77e-171 resD - - T ko:K07775 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PFOHNOAK_01685 0.0 resE 2.7.13.3 - T ko:K07651 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PFOHNOAK_01686 3.22e-135 sigX - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
PFOHNOAK_01687 3.73e-245 rsiX - - - - - - -
PFOHNOAK_01688 0.0 serA 1.1.1.399, 1.1.1.95 - E ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PFOHNOAK_01689 2.16e-122 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
PFOHNOAK_01690 5.88e-55 fer - - C ko:K05337 - ko00000 Ferredoxin
PFOHNOAK_01691 1.32e-247 ypbB 5.1.3.1 - S ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 protein conserved in bacteria
PFOHNOAK_01692 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
PFOHNOAK_01693 1.4e-127 ypbD - - S ko:K07052 - ko00000 metal-dependent membrane protease
PFOHNOAK_01694 6.15e-126 ypbE - - M - - - Lysin motif
PFOHNOAK_01695 1.92e-111 ypbF - - S - - - Protein of unknown function (DUF2663)
PFOHNOAK_01696 2.22e-187 ypbG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
PFOHNOAK_01697 3.35e-137 mecB - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
PFOHNOAK_01698 1.81e-311 gudB 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
PFOHNOAK_01699 7.53e-239 ypdA 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 COG0492 Thioredoxin reductase
PFOHNOAK_01700 6.4e-156 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
PFOHNOAK_01701 2.09e-210 sleB 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Spore cortex-lytic enzyme
PFOHNOAK_01702 0.0 ypeB - - H ko:K06313 - ko00000 sporulation protein
PFOHNOAK_01703 9.47e-77 ypfA - - M - - - Flagellar protein YcgR
PFOHNOAK_01704 7.86e-18 - - - S - - - Family of unknown function (DUF5359)
PFOHNOAK_01705 2.02e-146 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
PFOHNOAK_01706 8.14e-264 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
PFOHNOAK_01707 2.81e-236 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
PFOHNOAK_01708 1.87e-12 - - - S - - - YpzI-like protein
PFOHNOAK_01709 5.09e-135 yphA - - - - - - -
PFOHNOAK_01710 0.0 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
PFOHNOAK_01711 4.93e-244 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
PFOHNOAK_01712 3.25e-23 yphE - - S - - - Protein of unknown function (DUF2768)
PFOHNOAK_01713 3.97e-172 yphF - - - - - - -
PFOHNOAK_01714 0.0 spoIVA - - S ko:K06398 - ko00000 ATPase. Has a role at an early stage in the morphogenesis of the spore coat
PFOHNOAK_01715 1.07e-57 hbs - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
PFOHNOAK_01716 6.27e-131 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
PFOHNOAK_01717 6.23e-47 mtrB - - K ko:K06285 - ko00000,ko03000 Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
PFOHNOAK_01718 3.96e-177 hepS 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
PFOHNOAK_01719 7.76e-169 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
PFOHNOAK_01720 2.29e-251 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
PFOHNOAK_01721 2.86e-102 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
PFOHNOAK_01722 1.96e-178 cheR 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 COG1352 Methylase of chemotaxis methyl-accepting proteins
PFOHNOAK_01723 9.75e-276 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
PFOHNOAK_01724 2.61e-259 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
PFOHNOAK_01725 2.93e-79 aroH 5.4.99.5 - E ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
PFOHNOAK_01726 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PFOHNOAK_01727 1.52e-207 trpD 2.4.2.18, 4.1.3.27 - E ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PFOHNOAK_01728 2.36e-167 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
PFOHNOAK_01729 1.68e-146 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
PFOHNOAK_01730 1.42e-289 trpB 4.2.1.20 - E ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
PFOHNOAK_01731 1.14e-186 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
PFOHNOAK_01732 2.6e-258 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PFOHNOAK_01733 1.39e-257 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
PFOHNOAK_01734 1.03e-303 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
PFOHNOAK_01735 8.74e-298 ypiA - - S - - - COG0457 FOG TPR repeat
PFOHNOAK_01736 2.6e-129 ypiB - - S - - - Belongs to the UPF0302 family
PFOHNOAK_01737 3.34e-101 ypiF - - S - - - Protein of unknown function (DUF2487)
PFOHNOAK_01738 2.86e-127 qcrA - - C ko:K03886 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Menaquinol-cytochrome c reductase
PFOHNOAK_01739 8.76e-166 qcrB - - C ko:K03887 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG1290 Cytochrome b subunit of the bc complex
PFOHNOAK_01740 2.33e-190 qcrC - - C ko:K03888 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Menaquinol-cytochrome c reductase cytochrome b c subunit
PFOHNOAK_01741 2.17e-135 ypjA - - S - - - membrane
PFOHNOAK_01742 1.96e-180 ypjB - - S - - - sporulation protein
PFOHNOAK_01743 9.57e-288 - 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
PFOHNOAK_01744 4.31e-199 ypjC - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
PFOHNOAK_01745 2.47e-74 ypjD - - S - - - Nucleotide pyrophosphohydrolase
PFOHNOAK_01746 9.78e-189 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
PFOHNOAK_01747 6.19e-94 mgsA 4.2.3.3 - G ko:K01734 ko00640,ko01120,map00640,map01120 ko00000,ko00001,ko01000 methylglyoxal synthase
PFOHNOAK_01748 4.48e-170 bshB1 - - S ko:K01463 - ko00000,ko01000 proteins, LmbE homologs
PFOHNOAK_01749 2.55e-269 bshA - GT4 M ko:K00754 - ko00000,ko01000 N-acetyl-alpha-D-glucosaminyl L-malate synthase
PFOHNOAK_01750 7.21e-281 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
PFOHNOAK_01751 3.15e-230 birA 6.3.4.15 - K ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
PFOHNOAK_01752 2.21e-190 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
PFOHNOAK_01753 1.99e-202 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
PFOHNOAK_01754 2.41e-84 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
PFOHNOAK_01755 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
PFOHNOAK_01756 1.52e-32 ypmA - - S - - - Protein of unknown function (DUF4264)
PFOHNOAK_01757 7.93e-104 ypmB - - S - - - protein conserved in bacteria
PFOHNOAK_01758 8.45e-283 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
PFOHNOAK_01759 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 asparaginyl-tRNA
PFOHNOAK_01760 3.42e-167 dnaD - - L ko:K02086 - ko00000 DNA replication protein DnaD
PFOHNOAK_01761 1.7e-156 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PFOHNOAK_01762 2.56e-119 ypoC - - - - - - -
PFOHNOAK_01763 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
PFOHNOAK_01764 7.27e-145 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
PFOHNOAK_01765 2e-239 yppC - - S - - - Protein of unknown function (DUF2515)
PFOHNOAK_01766 0.000542 - - - - ko:K06430 - ko00000 -
PFOHNOAK_01770 9.54e-81 yppG - - S - - - YppG-like protein
PFOHNOAK_01771 7.23e-93 hspX - - O ko:K06335,ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
PFOHNOAK_01772 9.93e-115 ypqE - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 COG2190 Phosphotransferase system IIA components
PFOHNOAK_01773 0.0 yprA - - L ko:K06877 - ko00000 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
PFOHNOAK_01774 8.55e-288 yprB - - L ko:K07502 - ko00000 RNase_H superfamily
PFOHNOAK_01776 9.36e-48 cotD - - S ko:K06327 - ko00000 Inner spore coat protein D
PFOHNOAK_01777 5.42e-128 ypsA - - S - - - Belongs to the UPF0398 family
PFOHNOAK_01778 5.52e-61 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
PFOHNOAK_01779 9.41e-279 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
PFOHNOAK_01780 1.43e-101 yqgA - - - - - - -
PFOHNOAK_01781 6.91e-31 - - - S - - - YpzG-like protein
PFOHNOAK_01783 0.0 ypvA 3.6.4.12 - KL ko:K03722 - ko00000,ko01000,ko03400 COG1199 Rad3-related DNA helicases
PFOHNOAK_01784 0.0 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
PFOHNOAK_01785 8.16e-129 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
PFOHNOAK_01786 2.93e-297 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine
PFOHNOAK_01787 4.67e-07 - - - - - - - -
PFOHNOAK_01788 4.25e-128 yrdC - - Q - - - Isochorismatase family
PFOHNOAK_01789 1.08e-73 ydfR - - S - - - Protein of unknown function (DUF421)
PFOHNOAK_01790 1.78e-29 ydfR - - S - - - Protein of unknown function (DUF421)
PFOHNOAK_01791 6.89e-08 - - - S - - - Bacillus cereus group antimicrobial protein
PFOHNOAK_01792 1.17e-65 MGMT - - L ko:K07443 - ko00000 6-O-methylguanine DNA methyltransferase, DNA binding domain
PFOHNOAK_01793 1.77e-136 - - - J - - - Acetyltransferase (GNAT) domain
PFOHNOAK_01794 9.52e-264 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
PFOHNOAK_01795 1.26e-117 ypbQ - - S ko:K16168 - ko00000,ko01008 protein conserved in bacteria
PFOHNOAK_01796 0.0 ypbR - - S - - - Dynamin family
PFOHNOAK_01797 1.17e-51 ypbS - - S - - - Protein of unknown function (DUF2533)
PFOHNOAK_01798 2.44e-10 - - - - - - - -
PFOHNOAK_01799 1.3e-207 ypcP - - L - - - 5'3' exonuclease
PFOHNOAK_01801 2.47e-88 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease
PFOHNOAK_01802 9.33e-153 ypdP - - S ko:K09125 - ko00000 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
PFOHNOAK_01803 1.69e-158 ypeP 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 COG0328 Ribonuclease HI
PFOHNOAK_01804 6.59e-40 ypeQ - - S - - - Zinc-finger
PFOHNOAK_01805 3.78e-48 - - - S - - - Protein of unknown function (DUF2564)
PFOHNOAK_01806 5.19e-17 degR - - - - - - -
PFOHNOAK_01807 5.12e-42 cspD - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
PFOHNOAK_01808 9e-276 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
PFOHNOAK_01809 2.3e-227 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PFOHNOAK_01810 2.18e-110 bsaA 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
PFOHNOAK_01811 3.26e-128 yagB - - S ko:K06950 - ko00000 phosphohydrolase
PFOHNOAK_01812 3.51e-200 ypgR - - C - - - COG0694 Thioredoxin-like proteins and domains
PFOHNOAK_01813 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
PFOHNOAK_01814 4.8e-99 yphP - - S - - - Belongs to the UPF0403 family
PFOHNOAK_01815 2.46e-172 ypiP - - AJ - - - Putative SAM-dependent methyltransferase
PFOHNOAK_01816 2.17e-146 ypjP - - S - - - YpjP-like protein
PFOHNOAK_01817 3.6e-203 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PFOHNOAK_01818 4.27e-117 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PFOHNOAK_01819 5.51e-147 ypkP 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
PFOHNOAK_01820 5.24e-143 yplQ - - S ko:K11068 - ko00000,ko02042 protein, Hemolysin III
PFOHNOAK_01821 1.86e-220 yplP - - K - - - Transcriptional regulator
PFOHNOAK_01822 8.57e-309 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PFOHNOAK_01823 7.13e-52 ypmP - - S - - - Protein of unknown function (DUF2535)
PFOHNOAK_01824 5.97e-136 ypmQ - - S ko:K07152 - ko00000,ko03029 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
PFOHNOAK_01825 1.43e-173 ypmR - - E - - - GDSL-like Lipase/Acylhydrolase
PFOHNOAK_01826 1.6e-125 ypmS - - S - - - protein conserved in bacteria
PFOHNOAK_01827 3.35e-89 ypoP - - K - - - transcriptional
PFOHNOAK_01828 1.7e-133 msrB 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PFOHNOAK_01829 4.61e-106 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
PFOHNOAK_01830 8.41e-135 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
PFOHNOAK_01831 0.0 yokA - - L - - - Recombinase
PFOHNOAK_01833 2.98e-116 yokH - - G - - - SMI1 / KNR4 family
PFOHNOAK_01834 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
PFOHNOAK_01835 3.88e-68 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
PFOHNOAK_01836 1.23e-113 yokK - - S - - - SMI1 / KNR4 family
PFOHNOAK_01837 2.68e-39 - - - S - - - Acetyltransferase (GNAT) domain
PFOHNOAK_01841 2.29e-214 - - - S - - - amine dehydrogenase activity
PFOHNOAK_01843 3.09e-266 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
PFOHNOAK_01844 1.85e-99 yoqH - - M - - - LysM domain
PFOHNOAK_01848 7.43e-26 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 - L ko:K01971,ko:K10747 ko03030,ko03410,ko03420,ko03430,ko03450,map03030,map03410,map03420,map03430,map03450 ko00000,ko00001,ko01000,ko03032,ko03400 ATP-dependent DNA ligase
PFOHNOAK_01849 5.37e-101 - - - - - - - -
PFOHNOAK_01855 3.54e-95 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
PFOHNOAK_01856 2.5e-279 phy 3.1.3.8 - I ko:K01083 ko00562,map00562 ko00000,ko00001,ko01000 Myo-inositol-hexaphosphate 3-phosphohydrolase
PFOHNOAK_01857 5.02e-228 cgeB - - S ko:K06320 - ko00000 Spore maturation protein
PFOHNOAK_01858 1.22e-87 cgeA - - - ko:K06319 - ko00000 -
PFOHNOAK_01859 1.11e-60 cgeC - - - ko:K06321 - ko00000 -
PFOHNOAK_01860 5.36e-308 cgeD - - M ko:K06322 - ko00000 maturation of the outermost layer of the spore
PFOHNOAK_01861 8.11e-185 yiiD - - K ko:K06323 - ko00000 acetyltransferase
PFOHNOAK_01863 3.7e-63 - - - L - - - Bacterial transcription activator, effector binding domain
PFOHNOAK_01864 4.63e-310 yodT - - H - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PFOHNOAK_01865 9.76e-161 atoD 2.8.3.8, 2.8.3.9 - I ko:K01034 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
PFOHNOAK_01866 4.64e-160 atoA 2.8.3.8, 2.8.3.9 - I ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
PFOHNOAK_01867 0.0 yodQ 3.5.1.16, 3.5.1.18 - E ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetylornithine deacetylase
PFOHNOAK_01868 5.71e-203 yodP 2.3.1.264 - K ko:K21935 - ko00000,ko01000 Acetyltransferase (GNAT) family
PFOHNOAK_01869 0.0 kamA 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 lysine 2,3-aminomutase
PFOHNOAK_01870 2.83e-62 yokU - - S - - - YokU-like protein, putative antitoxin
PFOHNOAK_01871 2.02e-47 yozE - - S - - - Belongs to the UPF0346 family
PFOHNOAK_01872 1.36e-33 - - - E - - - lactoylglutathione lyase activity
PFOHNOAK_01873 1.9e-161 yodN - - - - - - -
PFOHNOAK_01875 9.77e-34 yozD - - S - - - YozD-like protein
PFOHNOAK_01876 1.76e-132 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
PFOHNOAK_01877 1.16e-72 yodL - - S - - - YodL-like
PFOHNOAK_01879 1.05e-161 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
PFOHNOAK_01880 4.49e-192 yodJ 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
PFOHNOAK_01881 2.5e-32 yodI - - - - - - -
PFOHNOAK_01882 7.15e-165 yodH - - Q - - - Methyltransferase
PFOHNOAK_01883 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
PFOHNOAK_01884 1.23e-169 yydK - - K ko:K03489 - ko00000,ko03000 Transcriptional regulator
PFOHNOAK_01885 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
PFOHNOAK_01886 0.0 - 3.2.1.45 GH30 M ko:K01201 ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142 ko00000,ko00001,ko01000 Glycosyl hydrolase family 30 beta sandwich domain
PFOHNOAK_01887 0.0 yodF - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PFOHNOAK_01888 5.66e-28 - - - S - - - Protein of unknown function (DUF3311)
PFOHNOAK_01889 2.2e-221 yodE - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
PFOHNOAK_01890 2.43e-140 yahD - - S ko:K06999 - ko00000 Carboxylesterase
PFOHNOAK_01891 1.35e-138 yodC - - C - - - nitroreductase
PFOHNOAK_01892 2.42e-74 yodB - - K - - - transcriptional
PFOHNOAK_01893 1.86e-90 yoaQ - - S - - - Evidence 4 Homologs of previously reported genes of
PFOHNOAK_01894 3.02e-88 iolK - - S - - - tautomerase
PFOHNOAK_01896 1.91e-103 yozR - - S - - - COG0071 Molecular chaperone (small heat shock protein)
PFOHNOAK_01897 5.73e-208 rarD - - S ko:K05786 - ko00000,ko02000 -transporter
PFOHNOAK_01898 1.05e-30 - - - - - - - -
PFOHNOAK_01899 3.3e-79 yojF - - S - - - Protein of unknown function (DUF1806)
PFOHNOAK_01900 2.24e-162 yojG - - S ko:K22135 - ko00000,ko01000 deacetylase
PFOHNOAK_01901 5.03e-194 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
PFOHNOAK_01902 1.16e-301 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
PFOHNOAK_01904 5.48e-143 dacB 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
PFOHNOAK_01905 3.19e-283 - - - CG - - - UDP-glucoronosyl and UDP-glucosyl transferase
PFOHNOAK_01906 8.28e-291 - - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
PFOHNOAK_01907 4.23e-141 sodC 1.15.1.1 - P ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
PFOHNOAK_01908 4.2e-209 yojN - - S ko:K04748 - ko00000 ATPase family associated with various cellular activities (AAA)
PFOHNOAK_01909 0.0 yojO - - P - - - Von Willebrand factor
PFOHNOAK_01910 0.0 odhA 1.2.4.2 - C ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
PFOHNOAK_01911 7.41e-263 odhB 2.3.1.61 - C ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
PFOHNOAK_01912 5.88e-176 - - - S - - - Metallo-beta-lactamase superfamily
PFOHNOAK_01913 7.77e-214 yocS - - S ko:K03453 - ko00000 -transporter
PFOHNOAK_01914 5.92e-298 yocR - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
PFOHNOAK_01915 9.6e-212 sodF 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Superoxide dismutase
PFOHNOAK_01916 0.0 sqhC 4.2.1.137 - I ko:K18115 - ko00000,ko01000 COG1657 Squalene cyclase
PFOHNOAK_01917 0.0 dhaS 1.2.1.3, 1.2.1.39 - C ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
PFOHNOAK_01918 1.35e-42 yozC - - - - - - -
PFOHNOAK_01920 5.32e-75 yozO - - S - - - Bacterial PH domain
PFOHNOAK_01921 6.36e-50 yocN - - - - - - -
PFOHNOAK_01922 9.63e-60 yozN - - - - - - -
PFOHNOAK_01923 2.29e-116 yocM - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
PFOHNOAK_01925 3.05e-12 yocL - - - - - - -
PFOHNOAK_01926 2.23e-79 yocK - - T - - - general stress protein
PFOHNOAK_01928 2.32e-144 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
PFOHNOAK_01929 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
PFOHNOAK_01930 1.46e-160 yocH - - M - - - COG1388 FOG LysM repeat
PFOHNOAK_01932 1.11e-239 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 peptidase S66
PFOHNOAK_01933 3.78e-122 yocC - - - - - - -
PFOHNOAK_01934 8.29e-180 - - - J - - - Protein required for attachment to host cells
PFOHNOAK_01935 1.33e-117 yozB - - S ko:K08976 - ko00000 membrane
PFOHNOAK_01936 1.19e-157 yocA - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
PFOHNOAK_01937 2.58e-71 czrA - - K ko:K22043 - ko00000,ko03000 transcriptional
PFOHNOAK_01938 1.57e-118 yobW - - - - - - -
PFOHNOAK_01939 9.42e-173 yobT - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
PFOHNOAK_01940 4.71e-120 yobS - - K - - - Transcriptional regulator
PFOHNOAK_01941 1.45e-170 yobQ - - K - - - helix_turn_helix, arabinose operon control protein
PFOHNOAK_01942 2.12e-70 csaA - - J ko:K06878 - ko00000 tRNA-binding protein
PFOHNOAK_01943 5.02e-79 ykvN - - K - - - Transcriptional regulator
PFOHNOAK_01944 8.25e-167 ykvO - - IQ - - - Enoyl-(Acyl carrier protein) reductase
PFOHNOAK_01945 1.99e-58 - - - - - - - -
PFOHNOAK_01946 2.13e-124 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
PFOHNOAK_01948 0.0 yoaE - - C - - - belongs to the prokaryotic molybdopterin-containing oxidoreductase family
PFOHNOAK_01949 1.8e-247 yoaD 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PFOHNOAK_01950 0.0 lsrK 2.7.1.189 - G ko:K11216 ko02024,map02024 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
PFOHNOAK_01951 2.11e-259 yoaB - - EGP - - - the major facilitator superfamily
PFOHNOAK_01952 4.6e-171 yoxB - - - - - - -
PFOHNOAK_01953 7.75e-53 - - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
PFOHNOAK_01954 2.43e-157 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
PFOHNOAK_01955 8.08e-79 rtp - - K - - - Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
PFOHNOAK_01956 8.04e-180 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PFOHNOAK_01957 2.31e-258 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PFOHNOAK_01958 1.7e-204 gltC - - K ko:K09681 - ko00000,ko03000 Transcriptional regulator
PFOHNOAK_01959 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
PFOHNOAK_01960 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
PFOHNOAK_01961 2.22e-233 yogA - - C ko:K13955 - ko00000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
PFOHNOAK_01962 3.54e-197 gltR1 - - K ko:K21959 - ko00000,ko03000 Transcriptional regulator
PFOHNOAK_01963 3.18e-07 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PFOHNOAK_01964 1.34e-66 - - - K - - - Helix-turn-helix domain
PFOHNOAK_01965 6.52e-254 - - - EGP ko:K08164 - ko00000,ko02000 -transporter
PFOHNOAK_01966 0.0 ggt 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
PFOHNOAK_01967 9.51e-47 yoeD - - G - - - Helix-turn-helix domain
PFOHNOAK_01968 3.97e-125 - - - L - - - Integrase
PFOHNOAK_01970 8.67e-124 yoeB - - S - - - IseA DL-endopeptidase inhibitor
PFOHNOAK_01971 5.01e-310 yoeA - - V - - - MATE efflux family protein
PFOHNOAK_01972 1.07e-236 yoxA 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
PFOHNOAK_01973 0.0 dacC 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
PFOHNOAK_01974 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PFOHNOAK_01975 0.0 - - - Q ko:K15665 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PFOHNOAK_01976 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PFOHNOAK_01977 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PFOHNOAK_01978 0.0 - - - Q ko:K15656,ko:K15668 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 D-alanine [D-alanyl carrier protein] ligase activity
PFOHNOAK_01979 1.38e-84 yngL - - S - - - Protein of unknown function (DUF1360)
PFOHNOAK_01980 0.0 yngK - - T - - - Glycosyl hydrolase-like 10
PFOHNOAK_01981 1.53e-267 yngJ 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
PFOHNOAK_01982 0.0 yngI - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
PFOHNOAK_01983 0.0 yngH 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
PFOHNOAK_01984 2.77e-41 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin carboxyl carrier protein
PFOHNOAK_01985 5.77e-213 yngG 4.1.3.4 - E ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA lyase
PFOHNOAK_01986 3.01e-179 yngF - - I - - - Belongs to the enoyl-CoA hydratase isomerase family
PFOHNOAK_01987 0.0 yngE - - I - - - COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
PFOHNOAK_01988 5.33e-135 yngC - - S - - - SNARE associated Golgi protein
PFOHNOAK_01989 8.07e-203 yngB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
PFOHNOAK_01990 1.21e-90 yngA - - S - - - membrane
PFOHNOAK_01991 1.34e-185 bioW 6.2.1.14 - H ko:K01906 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
PFOHNOAK_01992 0.0 bioA 2.6.1.105, 2.6.1.62 - H ko:K00833,ko:K19563 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
PFOHNOAK_01993 6.27e-270 bioF 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
PFOHNOAK_01994 1.19e-163 bioD 6.3.3.3 - H ko:K01935 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
PFOHNOAK_01995 1.12e-246 bioB 2.8.1.6 - H ko:K01012 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
PFOHNOAK_01996 1.28e-275 bioI 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
PFOHNOAK_01997 0.0 yxjC - - EG - - - COG2610 H gluconate symporter and related permeases
PFOHNOAK_01998 2.1e-160 scoA 2.8.3.5 - I ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
PFOHNOAK_01999 1.83e-156 scoB 2.8.3.5 - I ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
PFOHNOAK_02000 3.23e-175 yxjF 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
PFOHNOAK_02001 1.82e-276 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
PFOHNOAK_02002 0.0 nrsA - - Q ko:K15661 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PFOHNOAK_02003 0.0 - - - Q ko:K15662,ko:K15663 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PFOHNOAK_02004 0.0 - - - Q ko:K15662,ko:K15663 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PFOHNOAK_02005 0.0 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
PFOHNOAK_02006 1.87e-315 ynfF 3.2.1.136 GH5 G ko:K15924 - ko00000,ko01000 Glycosyl hydrolase family 30 beta sandwich domain
PFOHNOAK_02007 1.8e-162 - - - T - - - Transcriptional regulatory protein, C terminal
PFOHNOAK_02008 9.54e-303 - - - T - - - Histidine kinase
PFOHNOAK_02009 2.03e-67 yvlA - - S - - - Domain of unknown function (DUF4870)
PFOHNOAK_02010 0.0 bglC5 3.2.1.4 GH5,GH9 G ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 PFAM glycoside hydrolase family 5
PFOHNOAK_02011 9.95e-06 - - - S - - - Platelet-activating factor acetylhydrolase, isoform II
PFOHNOAK_02012 1.45e-73 - - - S - - - Platelet-activating factor acetylhydrolase, isoform II
PFOHNOAK_02014 1.23e-35 yxlH - - EGP - - - Major Facilitator Superfamily
PFOHNOAK_02015 0.0 yndJ - - S - - - YndJ-like protein
PFOHNOAK_02016 1.92e-100 - - - S - - - Domain of unknown function (DUF4166)
PFOHNOAK_02017 8.13e-199 yndG - - S - - - DoxX-like family
PFOHNOAK_02018 9.83e-281 exuT - - G ko:K08191,ko:K08194 - ko00000,ko02000 Sugar (and other) transporter
PFOHNOAK_02019 3.39e-229 regR - - K ko:K02525 - ko00000,ko03000 transcriptional
PFOHNOAK_02020 6.56e-188 yjmF - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
PFOHNOAK_02021 3.12e-268 uxuA 4.2.1.8 - G ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of D-mannonate
PFOHNOAK_02022 1.02e-144 kdgA 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 2-dehydro-3-deoxy-phosphogluconate aldolase
PFOHNOAK_02023 3.46e-241 yjmD 1.1.1.380 - E ko:K08322 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
PFOHNOAK_02024 1.29e-230 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0524 Sugar kinases, ribokinase family
PFOHNOAK_02025 0.0 alsT - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
PFOHNOAK_02026 1.82e-63 ynfC - - - - - - -
PFOHNOAK_02027 3.14e-19 - - - - - - - -
PFOHNOAK_02028 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PFOHNOAK_02029 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PFOHNOAK_02030 9.94e-90 yneT - - S ko:K06929 - ko00000 CoA-binding protein
PFOHNOAK_02031 6.13e-119 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
PFOHNOAK_02032 3.13e-65 yneR - - S - - - Belongs to the HesB IscA family
PFOHNOAK_02033 9.11e-69 yneQ - - - - - - -
PFOHNOAK_02034 2.94e-97 yneP - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
PFOHNOAK_02035 1e-43 tlp - - S ko:K06434 - ko00000 Belongs to the Tlp family
PFOHNOAK_02037 2.66e-09 - - - S - - - Fur-regulated basic protein B
PFOHNOAK_02038 5.75e-119 yneN - - CO - - - alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
PFOHNOAK_02039 0.0 citB 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
PFOHNOAK_02040 6.2e-22 sspO - - S ko:K06432 - ko00000 Belongs to the SspO family
PFOHNOAK_02041 1.97e-27 sspP - - S ko:K06433 - ko00000 Belongs to the SspP family
PFOHNOAK_02042 2.44e-82 cotM - - O ko:K06335 - ko00000 Spore coat protein
PFOHNOAK_02043 1.97e-97 yneK - - S - - - Protein of unknown function (DUF2621)
PFOHNOAK_02044 7.59e-97 yneJ - - O - - - COG4846 Membrane protein involved in cytochrome C biogenesis
PFOHNOAK_02045 2.47e-76 ccdB - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 cheY-homologous receiver domain
PFOHNOAK_02046 4.47e-164 ccdA - - O ko:K06196 - ko00000,ko02000 cytochrome c biogenesis protein
PFOHNOAK_02047 1.97e-33 ynzD - - S - - - Spo0E like sporulation regulatory protein
PFOHNOAK_02048 6.2e-39 yneF - - S ko:K09976 - ko00000 UPF0154 protein
PFOHNOAK_02049 6.25e-106 yneE - - S - - - Sporulation inhibitor of replication protein sirA
PFOHNOAK_02050 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PFOHNOAK_02051 2.33e-43 ynzC - - S - - - UPF0291 protein
PFOHNOAK_02052 5.22e-145 yneB - - L - - - resolvase
PFOHNOAK_02053 2.38e-66 yneA - - D - - - Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
PFOHNOAK_02054 3.18e-141 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PFOHNOAK_02056 7.53e-94 yndM - - S - - - Protein of unknown function (DUF2512)
PFOHNOAK_02057 4.43e-185 - - - O - - - COG0330 Membrane protease subunits, stomatin prohibitin homologs
PFOHNOAK_02058 8.63e-12 - - - - - - - -
PFOHNOAK_02059 1.79e-178 yndL - - S - - - Replication protein
PFOHNOAK_02060 1.74e-101 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
PFOHNOAK_02061 0.0 yobO - - M - - - Pectate lyase superfamily protein
PFOHNOAK_02063 2.91e-121 yvgO - - - - - - -
PFOHNOAK_02064 9.28e-07 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
PFOHNOAK_02065 1.65e-152 - - AA10,CBM73 S ko:K03933 - ko00000 Pfam:Chitin_bind_3
PFOHNOAK_02066 3.27e-255 - - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PFOHNOAK_02067 1.08e-149 - - - S - - - Domain of unknown function (DUF3885)
PFOHNOAK_02068 1.1e-126 - - - J - - - Acetyltransferase (GNAT) domain
PFOHNOAK_02069 5.05e-184 yoaP - - K - - - YoaP-like
PFOHNOAK_02072 8.07e-235 adhP 1.1.1.1 - C ko:K00001,ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
PFOHNOAK_02073 6.73e-87 dinB - - S - - - DinB family
PFOHNOAK_02074 2.65e-154 yobV - - K - - - WYL domain
PFOHNOAK_02075 1.28e-26 - - - - - - - -
PFOHNOAK_02080 0.0 pps 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
PFOHNOAK_02081 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 xylulose kinase
PFOHNOAK_02083 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
PFOHNOAK_02084 3.1e-269 xylR - - GK - - - ROK family
PFOHNOAK_02085 0.0 xynB 3.2.1.37 GH43 G ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
PFOHNOAK_02086 4.49e-316 xynP - - G ko:K03292 - ko00000 MFS/sugar transport protein
PFOHNOAK_02087 1.21e-265 mrjp - - G - - - Major royal jelly protein
PFOHNOAK_02088 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
PFOHNOAK_02089 1.26e-87 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 transcriptional
PFOHNOAK_02090 4.1e-311 ynbB - - P - - - COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
PFOHNOAK_02091 3.83e-295 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PFOHNOAK_02092 1.55e-226 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
PFOHNOAK_02093 2.64e-149 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
PFOHNOAK_02094 1.06e-139 ymaB - - S - - - MutT family
PFOHNOAK_02095 6.19e-239 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PFOHNOAK_02096 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PFOHNOAK_02097 1.61e-88 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
PFOHNOAK_02098 9.42e-29 ymzA - - - - - - -
PFOHNOAK_02099 4.76e-56 - - - - - - - -
PFOHNOAK_02100 9e-46 hfq - - J ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
PFOHNOAK_02101 8.91e-220 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PFOHNOAK_02102 8.12e-75 ymaF - - S - - - YmaF family
PFOHNOAK_02104 1.5e-62 ebrA - - P ko:K11814 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
PFOHNOAK_02105 3.04e-71 ebrB - - P ko:K03297,ko:K11814,ko:K11815 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
PFOHNOAK_02106 6.98e-104 ymaD - - O - - - redox protein, regulator of disulfide bond formation
PFOHNOAK_02107 2.68e-161 ymaC - - S - - - Replication protein
PFOHNOAK_02108 8.61e-06 - - - - - - - -
PFOHNOAK_02109 0.0 aprX - - O ko:K17734 - ko00000,ko01000,ko01002 Belongs to the peptidase S8 family
PFOHNOAK_02110 7.97e-82 ymzB - - - - - - -
PFOHNOAK_02111 1.28e-152 yoaK - - S - - - Membrane
PFOHNOAK_02112 1.74e-101 nucB - - M - - - Deoxyribonuclease NucA/NucB
PFOHNOAK_02113 6.55e-292 cypA 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
PFOHNOAK_02114 0.0 - - - HQ ko:K13615 - ko00000,ko01004,ko01008 Beta-ketoacyl synthase
PFOHNOAK_02115 0.0 - - - IQ ko:K13611,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
PFOHNOAK_02116 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
PFOHNOAK_02117 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
PFOHNOAK_02118 0.0 - - - IQ ko:K13611,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
PFOHNOAK_02119 3.42e-180 pksI - - I ko:K15313 - ko00000,ko01008 Belongs to the enoyl-CoA hydratase isomerase family
PFOHNOAK_02120 1.76e-186 - - - I ko:K15312 - ko00000,ko01008 enoyl-CoA hydratase
PFOHNOAK_02121 1.73e-307 pksG 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
PFOHNOAK_02122 1.46e-46 acpK - - IQ ko:K15337 - ko00000,ko01008 Phosphopantetheine attachment site
PFOHNOAK_02123 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
PFOHNOAK_02124 2.6e-233 pksD - - Q ko:K15328 - ko00000,ko01008 Acyl transferase domain
PFOHNOAK_02125 3.88e-206 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
PFOHNOAK_02126 4.05e-166 pksB 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 Polyketide biosynthesis
PFOHNOAK_02128 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PFOHNOAK_02129 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PFOHNOAK_02130 7.09e-119 cotE - - S ko:K06328 - ko00000 Spore coat protein
PFOHNOAK_02131 2.11e-88 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
PFOHNOAK_02132 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PFOHNOAK_02133 2.89e-273 kbl 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
PFOHNOAK_02134 1.08e-246 tdh 1.1.1.103 - C ko:K00060 ko00260,map00260 ko00000,ko00001,ko01000 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
PFOHNOAK_02135 2.44e-49 spoVS - - S ko:K06416 - ko00000 Stage V sporulation protein S
PFOHNOAK_02136 3.72e-196 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 protein conserved in bacteria
PFOHNOAK_02137 2.91e-308 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
PFOHNOAK_02138 2.22e-278 pbpX - - V - - - Beta-lactamase
PFOHNOAK_02139 3.06e-239 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PFOHNOAK_02140 1.55e-292 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
PFOHNOAK_02141 1.36e-131 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PFOHNOAK_02142 9.53e-176 ymfM - - S ko:K15539 - ko00000 protein conserved in bacteria
PFOHNOAK_02143 3.14e-183 ymfK - - S - - - Protein of unknown function (DUF3388)
PFOHNOAK_02144 6.23e-56 ymfJ - - S - - - Protein of unknown function (DUF3243)
PFOHNOAK_02145 6.79e-163 ymfI 1.1.1.100 - S ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
PFOHNOAK_02146 3.77e-306 ymfH - - S - - - zinc protease
PFOHNOAK_02147 5.12e-303 albE - - S - - - Peptidase M16
PFOHNOAK_02148 0.0 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
PFOHNOAK_02149 1.2e-100 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
PFOHNOAK_02150 7.1e-293 ymfD - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
PFOHNOAK_02151 2.59e-171 ymfC - - K ko:K03710 - ko00000,ko03000 Transcriptional regulator
PFOHNOAK_02152 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
PFOHNOAK_02153 6.32e-42 - - - S - - - YlzJ-like protein
PFOHNOAK_02154 2.27e-166 tepA - - OU - - - COG0740 Protease subunit of ATP-dependent Clp proteases
PFOHNOAK_02155 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PFOHNOAK_02156 7.2e-202 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PFOHNOAK_02157 2e-282 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
PFOHNOAK_02158 4.09e-248 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PFOHNOAK_02159 1.93e-137 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
PFOHNOAK_02160 3.86e-205 dpaA - - CH ko:K06410 - ko00000 Dipicolinate synthase subunit A
PFOHNOAK_02161 2.17e-56 ymxH - - S - - - YlmC YmxH family
PFOHNOAK_02162 2.41e-298 mlpA - - S - - - Belongs to the peptidase M16 family
PFOHNOAK_02163 1.19e-231 ylxY - - G - - - Sporulation protein, polysaccharide deacetylase
PFOHNOAK_02164 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
PFOHNOAK_02165 4.12e-56 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PFOHNOAK_02166 1.44e-229 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
PFOHNOAK_02167 2.57e-221 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PFOHNOAK_02168 1.03e-73 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PFOHNOAK_02169 3.88e-60 ylxP - - S ko:K09764 - ko00000 protein conserved in bacteria
PFOHNOAK_02170 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PFOHNOAK_02171 6.16e-63 ylxQ - - J - - - ribosomal protein
PFOHNOAK_02172 6.76e-56 ylxR - - K ko:K07742 - ko00000 nucleic-acid-binding protein implicated in transcription termination
PFOHNOAK_02173 4.04e-264 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
PFOHNOAK_02174 9.4e-105 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
PFOHNOAK_02175 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PFOHNOAK_02176 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
PFOHNOAK_02177 4.66e-296 rasP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
PFOHNOAK_02178 6.31e-273 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
PFOHNOAK_02179 3.8e-179 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
PFOHNOAK_02180 2.22e-186 uppS 2.5.1.31 - I ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PFOHNOAK_02181 1.94e-118 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
PFOHNOAK_02182 7.09e-164 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
PFOHNOAK_02183 2.7e-199 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PFOHNOAK_02184 1.74e-167 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
PFOHNOAK_02185 3.52e-91 ylxL - - - - - - -
PFOHNOAK_02186 3.96e-177 sigD - - K ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PFOHNOAK_02187 1.65e-112 cheD 3.5.1.44 - NT ko:K03411 ko02030,map02030 ko00000,ko00001,ko01000,ko02035 Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
PFOHNOAK_02188 3.42e-142 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
PFOHNOAK_02189 2.49e-105 cheW - - NT ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 COG0835 Chemotaxis signal transduction protein
PFOHNOAK_02190 0.0 cheA 2.7.13.3 - NT ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 COG0643 Chemotaxis protein histidine kinase and related kinases
PFOHNOAK_02191 6.77e-247 cheB 3.1.1.61, 3.5.1.44 - NT ko:K03412 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
PFOHNOAK_02192 1.56e-200 ylxH - - D ko:K04562 - ko00000,ko02035 Belongs to the ParA family
PFOHNOAK_02193 1.79e-246 flhF - - N ko:K02404 - ko00000,ko02035 Flagellar biosynthesis regulator FlhF
PFOHNOAK_02194 0.0 flhA - - N ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PFOHNOAK_02195 1.03e-241 flhB - - N ko:K02401 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PFOHNOAK_02196 5.74e-168 fliR - - N ko:K02421 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthetic protein FliR
PFOHNOAK_02197 3.15e-51 fliQ - - N ko:K02420 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Role in flagellar biosynthesis
PFOHNOAK_02198 8.55e-142 fliP - - N ko:K02419 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Plays a role in the flagellum-specific transport system
PFOHNOAK_02199 9.34e-144 fliZ - - N ko:K02418 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthesis protein, FliO
PFOHNOAK_02200 2.12e-77 cheY - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 response regulator
PFOHNOAK_02201 6.97e-247 fliY - - N ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
PFOHNOAK_02202 5.43e-230 fliM - - N ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
PFOHNOAK_02203 6.59e-81 fliL - - N ko:K02415 - ko00000,ko02035 Controls the rotational direction of flagella during chemotaxis
PFOHNOAK_02204 4.62e-178 flgG - - N ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod
PFOHNOAK_02205 1.8e-95 flgD - - N ko:K02389 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod modification protein
PFOHNOAK_02206 3e-260 fliK - - N ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-length control protein
PFOHNOAK_02207 1.98e-88 ylxF - - S - - - MgtE intracellular N domain
PFOHNOAK_02208 2.17e-92 fliJ - - N ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar biosynthesis chaperone
PFOHNOAK_02209 1.05e-308 fliI 3.6.3.14 - NU ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 COG1157 Flagellar biosynthesis type III secretory pathway ATPase
PFOHNOAK_02210 5.36e-120 fliH - - NU ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 COG1317 Flagellar biosynthesis type III secretory pathway protein
PFOHNOAK_02211 2.48e-229 fliG - - N ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
PFOHNOAK_02212 0.0 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
PFOHNOAK_02213 1.51e-50 fliE - - N ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-basal body
PFOHNOAK_02214 2.63e-99 flgC - - N ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the flagella basal body rod proteins family
PFOHNOAK_02215 2.8e-84 flgB - - N ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
PFOHNOAK_02216 2.77e-175 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
PFOHNOAK_02217 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
PFOHNOAK_02218 7.38e-121 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
PFOHNOAK_02219 6.29e-220 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 tyrosine recombinase XerC
PFOHNOAK_02220 1.1e-313 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
PFOHNOAK_02221 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PFOHNOAK_02222 1.42e-213 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
PFOHNOAK_02223 7.59e-214 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
PFOHNOAK_02224 2.02e-270 sucC 6.2.1.5 - C ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
PFOHNOAK_02225 6.94e-59 ylqH - - S ko:K04061 - ko00000,ko02044 homolog of the cytoplasmic domain of flagellar protein FhlB
PFOHNOAK_02226 0.0 ylqG - - - - - - -
PFOHNOAK_02227 5.83e-175 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PFOHNOAK_02228 4.19e-202 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
PFOHNOAK_02229 8.14e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
PFOHNOAK_02230 5.67e-176 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
PFOHNOAK_02231 1.51e-121 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PFOHNOAK_02232 3.41e-80 ylqD - - S - - - YlqD protein
PFOHNOAK_02233 4.9e-49 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
PFOHNOAK_02234 1.13e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
PFOHNOAK_02235 9.92e-302 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PFOHNOAK_02236 1.97e-66 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
PFOHNOAK_02237 5.87e-180 - - - S - - - Phosphotransferase enzyme family
PFOHNOAK_02238 1.87e-224 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
PFOHNOAK_02239 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
PFOHNOAK_02240 1.43e-172 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
PFOHNOAK_02241 1.15e-43 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
PFOHNOAK_02242 8.61e-168 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
PFOHNOAK_02243 3.76e-218 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
PFOHNOAK_02244 3.14e-229 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
PFOHNOAK_02245 4.38e-121 fapR - - K - - - Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
PFOHNOAK_02246 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PFOHNOAK_02247 2.4e-201 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
PFOHNOAK_02248 4.15e-153 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
PFOHNOAK_02249 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
PFOHNOAK_02250 3.65e-78 yloU - - S - - - protein conserved in bacteria
PFOHNOAK_02251 3.49e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
PFOHNOAK_02252 4.52e-154 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
PFOHNOAK_02253 1.24e-150 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
PFOHNOAK_02254 2.53e-210 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
PFOHNOAK_02255 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
PFOHNOAK_02256 5.82e-177 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
PFOHNOAK_02257 1.52e-263 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
PFOHNOAK_02258 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PFOHNOAK_02259 5.32e-221 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PFOHNOAK_02260 1.18e-109 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
PFOHNOAK_02261 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PFOHNOAK_02262 1.47e-285 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PFOHNOAK_02263 2.53e-38 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
PFOHNOAK_02264 4.91e-144 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
PFOHNOAK_02265 3.97e-54 ylzA - - S ko:K09777 - ko00000 Belongs to the UPF0296 family
PFOHNOAK_02266 2.5e-197 yloC - - S - - - stress-induced protein
PFOHNOAK_02267 0.0 yloB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 COG0474 Cation transport ATPase
PFOHNOAK_02268 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
PFOHNOAK_02269 2.01e-102 sirC 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Siroheme synthase
PFOHNOAK_02270 1.02e-187 sirB 4.99.1.4 - S ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sirohydrochlorin ferrochelatase
PFOHNOAK_02271 3.28e-182 cobA 2.1.1.107 - H ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
PFOHNOAK_02272 9.22e-141 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
PFOHNOAK_02273 1.77e-283 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
PFOHNOAK_02274 3.87e-225 cysP - - P ko:K16331 - ko00000,ko02000 phosphate transporter
PFOHNOAK_02275 9.88e-181 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
PFOHNOAK_02277 1.74e-146 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PFOHNOAK_02278 1.74e-161 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
PFOHNOAK_02279 1.22e-220 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
PFOHNOAK_02280 1.75e-181 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
PFOHNOAK_02281 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarB family
PFOHNOAK_02282 6.23e-268 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
PFOHNOAK_02283 6.08e-312 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
PFOHNOAK_02284 2.44e-212 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
PFOHNOAK_02285 3.28e-295 pyrP - - F ko:K02824 - ko00000,ko02000 Xanthine uracil
PFOHNOAK_02286 2.21e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PFOHNOAK_02287 6.24e-215 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
PFOHNOAK_02288 5.07e-103 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PFOHNOAK_02289 4.75e-80 ylyA - - T - - - COG1734 DnaK suppressor protein
PFOHNOAK_02290 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PFOHNOAK_02291 1.85e-99 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
PFOHNOAK_02292 3.54e-181 ylmH - - S - - - conserved protein, contains S4-like domain
PFOHNOAK_02293 5.12e-56 ylmG - - S ko:K02221 - ko00000,ko02044 membrane
PFOHNOAK_02294 4.61e-85 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
PFOHNOAK_02295 5.23e-161 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
PFOHNOAK_02296 5.53e-205 ylmD - - S ko:K05810 - ko00000,ko01000 Belongs to the multicopper oxidase YfiH RL5 family
PFOHNOAK_02297 7.13e-52 ylmC - - S - - - sporulation protein
PFOHNOAK_02298 0.0 argE - - E ko:K20895 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Acetylornithine deacetylase
PFOHNOAK_02299 5.43e-185 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
PFOHNOAK_02300 9.33e-179 sigG - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PFOHNOAK_02301 7.35e-161 sigE - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PFOHNOAK_02302 2.75e-216 spoIIGA - - M ko:K06383 - ko00000,ko01000,ko01002 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
PFOHNOAK_02303 0.0 bpr - - O ko:K13276 - ko00000,ko01000,ko01002,ko03110 COG1404 Subtilisin-like serine proteases
PFOHNOAK_02304 2.61e-260 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PFOHNOAK_02305 1.57e-298 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
PFOHNOAK_02306 1.04e-176 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
PFOHNOAK_02307 7.87e-213 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
PFOHNOAK_02308 5.69e-259 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PFOHNOAK_02309 2.7e-236 spoVE - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
PFOHNOAK_02310 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PFOHNOAK_02311 2.87e-221 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PFOHNOAK_02312 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PFOHNOAK_02313 0.0 spoVD - - M ko:K08384 ko00550,map00550 ko00000,ko00001,ko01011 stage V sporulation protein D
PFOHNOAK_02314 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
PFOHNOAK_02315 2.4e-68 ftsL - - D - - - Essential cell division protein
PFOHNOAK_02316 6.76e-218 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
PFOHNOAK_02317 3.7e-101 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
PFOHNOAK_02318 0.0 bshC - - S ko:K22136 - ko00000 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
PFOHNOAK_02319 4.83e-210 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PFOHNOAK_02320 4.63e-116 ylbP - - K - - - n-acetyltransferase
PFOHNOAK_02321 3.13e-111 ylbO - - S ko:K06314 - ko00000,ko03000 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
PFOHNOAK_02322 1.71e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
PFOHNOAK_02323 4.69e-115 ylbN - - S ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
PFOHNOAK_02324 5.01e-293 ylbM - - S - - - Belongs to the UPF0348 family
PFOHNOAK_02325 1.52e-240 ylbL - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
PFOHNOAK_02326 2.48e-178 ylbK - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
PFOHNOAK_02327 1.68e-276 ylbJ - - S - - - Sporulation integral membrane protein YlbJ
PFOHNOAK_02328 6.83e-109 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PFOHNOAK_02329 1.01e-124 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
PFOHNOAK_02331 2.78e-57 ylbG - - S - - - UPF0298 protein
PFOHNOAK_02332 3.33e-97 ylbF - - S - - - Belongs to the UPF0342 family
PFOHNOAK_02333 1.73e-48 ylbE - - S - - - YlbE-like protein
PFOHNOAK_02334 1.64e-84 ylbD - - S - - - Putative coat protein
PFOHNOAK_02335 3.26e-254 ylbC - - S - - - protein with SCP PR1 domains
PFOHNOAK_02336 3.35e-96 ylbB - - T - - - COG0517 FOG CBS domain
PFOHNOAK_02337 1.68e-78 ylbA - - S - - - YugN-like family
PFOHNOAK_02338 3.45e-210 ctaG - - S ko:K02862 - ko00000 cytochrome c oxidase
PFOHNOAK_02339 2.04e-68 ctaF 1.9.3.1 - C ko:K02277 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
PFOHNOAK_02340 5.92e-142 ctaE 1.9.3.1 - C ko:K02276 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
PFOHNOAK_02341 0.0 ctaD 1.9.3.1 - C ko:K02274 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PFOHNOAK_02342 3.95e-251 ctaC 1.9.3.1 - C ko:K02275 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
PFOHNOAK_02343 2.07e-209 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
PFOHNOAK_02344 1.41e-213 ctaA - - O ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 ko00000,ko00001,ko00002,ko03029 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
PFOHNOAK_02345 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
PFOHNOAK_02346 2.02e-270 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
PFOHNOAK_02347 1.99e-58 ylaN - - S - - - Belongs to the UPF0358 family
PFOHNOAK_02348 8.95e-222 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
PFOHNOAK_02349 4.13e-109 ylaL - - S - - - Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
PFOHNOAK_02350 1.05e-310 ylaK - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
PFOHNOAK_02351 1.83e-136 ylaJ - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
PFOHNOAK_02352 1.37e-45 ylaI - - S - - - protein conserved in bacteria
PFOHNOAK_02353 4.05e-64 - - - S - - - YlaH-like protein
PFOHNOAK_02354 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
PFOHNOAK_02355 5.62e-33 - - - S - - - Family of unknown function (DUF5325)
PFOHNOAK_02356 8.65e-59 ylaE - - - - - - -
PFOHNOAK_02358 0.0 mpl 3.4.24.28, 3.4.24.29 - E ko:K01400,ko:K01401,ko:K19351 ko01503,ko05150,map01503,map05150 ko00000,ko00001,ko01000,ko01002 Peptidase M4
PFOHNOAK_02359 5.32e-108 ykzC - - S - - - Acetyltransferase (GNAT) family
PFOHNOAK_02360 8.12e-196 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase
PFOHNOAK_02361 7.89e-32 ykzI - - - - - - -
PFOHNOAK_02362 3.32e-154 yktB - - S - - - Belongs to the UPF0637 family
PFOHNOAK_02363 9.4e-57 yktA - - S - - - Belongs to the UPF0223 family
PFOHNOAK_02364 0.0 speA 4.1.1.17, 4.1.1.19 - E ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Arginine
PFOHNOAK_02365 5.41e-187 pdaA_2 3.5.1.104 - G ko:K01567,ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
PFOHNOAK_02366 5.61e-59 slp - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
PFOHNOAK_02367 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
PFOHNOAK_02368 8.47e-301 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
PFOHNOAK_02369 1.01e-226 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
PFOHNOAK_02370 7.79e-261 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
PFOHNOAK_02371 6.45e-265 - - - V - - - Beta-lactamase
PFOHNOAK_02372 0.0 - - - IQ - - - Phosphopantetheine attachment site
PFOHNOAK_02373 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
PFOHNOAK_02374 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
PFOHNOAK_02375 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
PFOHNOAK_02376 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
PFOHNOAK_02377 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 polyketide synthase
PFOHNOAK_02378 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
PFOHNOAK_02379 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
PFOHNOAK_02380 2.45e-132 ykyA - - L - - - Putative cell-wall binding lipoprotein
PFOHNOAK_02381 1.21e-06 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
PFOHNOAK_02382 1.14e-130 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
PFOHNOAK_02383 2.5e-186 ykrA - - S - - - hydrolases of the HAD superfamily
PFOHNOAK_02384 4.45e-42 ykzG - - S - - - Belongs to the UPF0356 family
PFOHNOAK_02385 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PFOHNOAK_02386 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
PFOHNOAK_02387 9.71e-148 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
PFOHNOAK_02388 4.85e-193 ykqA - - P - - - Gamma-glutamyl cyclotransferase, AIG2-like
PFOHNOAK_02389 1.61e-310 kinC 2.7.13.3 - T ko:K07698 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
PFOHNOAK_02390 7.46e-59 abrB - - K ko:K06284 - ko00000,ko03000 of stationary sporulation gene expression
PFOHNOAK_02391 3.72e-235 mreBH - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod-share determining protein MreBH
PFOHNOAK_02392 4.47e-18 - - - S - - - Uncharacterized protein YkpC
PFOHNOAK_02393 3.3e-300 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
PFOHNOAK_02394 9.92e-211 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PFOHNOAK_02395 0.0 ykpA - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
PFOHNOAK_02396 1.5e-49 ykoA - - - - - - -
PFOHNOAK_02397 3.77e-138 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
PFOHNOAK_02398 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
PFOHNOAK_02399 2.75e-213 pfkB 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
PFOHNOAK_02400 1.32e-169 fruR - - K ko:K03436 - ko00000,ko03000 Transcriptional regulator
PFOHNOAK_02401 3.47e-268 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
PFOHNOAK_02402 1.96e-156 yknY - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
PFOHNOAK_02403 7.77e-244 yknX - - M ko:K02005,ko:K13888 - ko00000,ko00002,ko02000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PFOHNOAK_02404 2.99e-136 yknW - - S - - - Yip1 domain
PFOHNOAK_02405 3.43e-45 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
PFOHNOAK_02406 8.37e-108 moaE 2.8.1.12 - H ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 COG0314 Molybdopterin converting factor, large subunit
PFOHNOAK_02407 3.6e-119 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
PFOHNOAK_02408 3.78e-307 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 molybdopterin
PFOHNOAK_02409 9.91e-241 moeB 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
PFOHNOAK_02410 6.72e-140 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
PFOHNOAK_02411 4e-215 yknT - - - ko:K06437 - ko00000 -
PFOHNOAK_02412 3.04e-126 rok - - K - - - Repressor of ComK
PFOHNOAK_02413 2.51e-98 ykuV - - CO - - - thiol-disulfide
PFOHNOAK_02414 1.48e-179 ykuT - - M ko:K22044 - ko00000,ko02000 Mechanosensitive ion channel
PFOHNOAK_02415 1.77e-51 ykuS - - S - - - Belongs to the UPF0180 family
PFOHNOAK_02416 7.99e-276 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
PFOHNOAK_02417 2.89e-129 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
PFOHNOAK_02418 6.2e-103 fld - - C ko:K03839 - ko00000 Flavodoxin
PFOHNOAK_02419 5.76e-212 ykuO - - - - - - -
PFOHNOAK_02420 5.24e-116 ykuN - - C ko:K03839 - ko00000 Flavodoxin
PFOHNOAK_02421 5.36e-215 ccpC - - K - - - Transcriptional regulator
PFOHNOAK_02422 8.55e-99 ykuL - - S - - - CBS domain
PFOHNOAK_02423 3.09e-35 ykzF - - S - - - Antirepressor AbbA
PFOHNOAK_02424 2.52e-119 ykuK - - S ko:K09776 - ko00000 Ribonuclease H-like
PFOHNOAK_02425 3.63e-50 ykuJ - - S - - - protein conserved in bacteria
PFOHNOAK_02426 2.21e-296 ykuI - - T - - - Diguanylate phosphodiesterase
PFOHNOAK_02428 3.03e-181 fadH 1.3.1.34 - IQ ko:K00219 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PFOHNOAK_02429 8.63e-196 ykuE - - S ko:K07098 - ko00000 Metallophosphoesterase
PFOHNOAK_02430 8.88e-117 ykuD - - S - - - protein conserved in bacteria
PFOHNOAK_02431 2.66e-307 ykuC - - EGP - - - COG0477 Permeases of the major facilitator superfamily
PFOHNOAK_02432 5.07e-108 ykyB - - S - - - YkyB-like protein
PFOHNOAK_02433 1.93e-213 cheV - - T ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 Chemotaxis protein CheV
PFOHNOAK_02434 6.38e-15 - - - - - - - -
PFOHNOAK_02435 1.62e-275 patA - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
PFOHNOAK_02436 0.0 kinA 2.7.13.3 - T ko:K02491 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PFOHNOAK_02437 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
PFOHNOAK_02438 1.74e-160 ykwD - - J - - - protein with SCP PR1 domains
PFOHNOAK_02439 3.4e-85 - - - - - - - -
PFOHNOAK_02440 1.4e-203 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
PFOHNOAK_02441 0.0 mcpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
PFOHNOAK_02442 4.12e-255 splB 4.1.99.14 - L ko:K03716 - ko00000,ko01000 Spore photoproduct lyase
PFOHNOAK_02443 3.63e-50 splA - - S ko:K06315 - ko00000,ko03000 Transcriptional regulator
PFOHNOAK_02444 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PFOHNOAK_02445 1.51e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPr
PFOHNOAK_02446 0.0 ptsG 2.7.1.199 - G ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
PFOHNOAK_02447 3.95e-199 glcT - - K ko:K03480,ko:K03488 - ko00000,ko03000 antiterminator
PFOHNOAK_02448 6.8e-223 ykvZ - - K - - - Transcriptional regulator
PFOHNOAK_02450 5.5e-262 ykvY 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
PFOHNOAK_02451 0.0 zosA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
PFOHNOAK_02452 1.22e-113 stoA - - CO - - - thiol-disulfide
PFOHNOAK_02453 2.19e-305 ykvU - - S - - - COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
PFOHNOAK_02454 9.83e-141 ykvT 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell Wall Hydrolase
PFOHNOAK_02455 7.17e-39 - - - - - - - -
PFOHNOAK_02456 5.43e-35 ykvS - - S - - - protein conserved in bacteria
PFOHNOAK_02457 2.54e-60 ykvR - - S - - - Protein of unknown function (DUF3219)
PFOHNOAK_02458 2.56e-124 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
PFOHNOAK_02459 5.06e-179 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
PFOHNOAK_02460 3.62e-102 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
PFOHNOAK_02461 2.72e-162 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
PFOHNOAK_02462 9.14e-245 - - - - - - - -
PFOHNOAK_02463 5.19e-230 ykvI - - S - - - membrane
PFOHNOAK_02464 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
PFOHNOAK_02465 4.74e-176 motA - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
PFOHNOAK_02466 4.04e-169 motB - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
PFOHNOAK_02467 3.91e-100 ykvE - - K ko:K15973 - ko00000,ko03000 transcriptional
PFOHNOAK_02468 0.0 kinD 2.7.13.3 - T ko:K13532 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
PFOHNOAK_02470 6.12e-123 mtnD 1.13.11.53, 1.13.11.54 - S ko:K08967 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
PFOHNOAK_02471 3.05e-145 mtnB 4.2.1.109 - E ko:K08964 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
PFOHNOAK_02472 9.55e-163 mtnX 3.1.3.87 - E ko:K08966 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
PFOHNOAK_02473 7.83e-289 mtnW 5.3.2.5 - G ko:K08965 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
PFOHNOAK_02474 2.1e-290 mtnE - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
PFOHNOAK_02475 1.64e-192 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
PFOHNOAK_02476 1.92e-284 mtnK 2.7.1.100 - F ko:K00899 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
PFOHNOAK_02477 1.09e-251 mtnA 5.3.1.23 - E ko:K08963 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
PFOHNOAK_02479 6.51e-114 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PFOHNOAK_02480 0.0 kinE 2.7.13.3 - T ko:K13533 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PFOHNOAK_02481 4.36e-240 ykrP - - G - - - COG3594 Fucose 4-O-acetylase and related acetyltransferases
PFOHNOAK_02482 1.78e-31 ykzE - - - - - - -
PFOHNOAK_02483 4.08e-146 - - - S - - - Protein of unknown function (DUF421)
PFOHNOAK_02484 3.8e-308 ktrD - - P - - - COG0168 Trk-type K transport systems, membrane components
PFOHNOAK_02485 2.12e-198 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
PFOHNOAK_02486 1.14e-161 ykrK - - S - - - Domain of unknown function (DUF1836)
PFOHNOAK_02487 5.7e-36 sspD - - S ko:K06421 - ko00000 small acid-soluble spore protein
PFOHNOAK_02488 7.25e-237 ykrI - - S - - - Anti-sigma factor N-terminus
PFOHNOAK_02489 6.02e-163 sigI - - K ko:K03093 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PFOHNOAK_02490 4.61e-170 ykoY - - P - - - COG0861 Membrane protein TerC, possibly involved in tellurium resistance
PFOHNOAK_02491 7.92e-129 ykoX - - S - - - membrane-associated protein
PFOHNOAK_02492 3.83e-199 ku - - L ko:K10979 ko03450,map03450 ko00000,ko00001,ko03400 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
PFOHNOAK_02493 0.0 ligD 6.5.1.1 - L ko:K01971 ko03450,map03450 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA ligase
PFOHNOAK_02494 7.68e-129 ykoP - - G - - - polysaccharide deacetylase
PFOHNOAK_02495 5.46e-105 ykoM - - K ko:K15973 - ko00000,ko03000 transcriptional
PFOHNOAK_02496 5.25e-37 ykoL - - - - - - -
PFOHNOAK_02497 1.11e-23 - - - - - - - -
PFOHNOAK_02498 1.23e-69 tnrA - - K - - - transcriptional
PFOHNOAK_02499 2.89e-308 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
PFOHNOAK_02501 3.63e-309 ydhD - - M - - - Glycosyl hydrolase
PFOHNOAK_02502 2.31e-126 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
PFOHNOAK_02503 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
PFOHNOAK_02504 2.66e-170 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
PFOHNOAK_02505 2.12e-188 yojH - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
PFOHNOAK_02506 7.39e-226 isp - - O ko:K13275 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
PFOHNOAK_02507 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
PFOHNOAK_02508 8.51e-157 nsr - - T - - - COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
PFOHNOAK_02509 1.81e-273 - - - EGP ko:K05820 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
PFOHNOAK_02510 1.3e-172 - - - M - - - PFAM Collagen triple helix repeat (20 copies)
PFOHNOAK_02511 5.84e-274 - - - M - - - Glycosyl transferase family 2
PFOHNOAK_02513 9.92e-77 - - - D - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
PFOHNOAK_02514 1.92e-92 ohrB - - O - - - Organic hydroperoxide resistance protein
PFOHNOAK_02515 3.83e-98 ohrR - - K - - - COG1846 Transcriptional regulators
PFOHNOAK_02516 2.69e-90 ohrA - - O - - - Organic hydroperoxide resistance protein
PFOHNOAK_02517 3.1e-287 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PFOHNOAK_02518 1.02e-260 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PFOHNOAK_02519 1.66e-217 purU 3.5.1.10 - F ko:K01433 ko00630,ko00670,map00630,map00670 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
PFOHNOAK_02520 1.22e-64 ykkD - - P ko:K18925 - ko00000,ko00002,ko02000 Multidrug resistance protein
PFOHNOAK_02521 3.36e-68 ykkC - - P ko:K18924 - ko00000,ko00002,ko02000 Multidrug resistance protein
PFOHNOAK_02522 8.68e-129 ykkB - - J - - - COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
PFOHNOAK_02523 2.16e-120 ykhA - - I - - - Acyl-CoA hydrolase
PFOHNOAK_02524 2.42e-203 ykgA - - E - - - Amidinotransferase
PFOHNOAK_02525 5.69e-261 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconolactonase
PFOHNOAK_02526 6.62e-231 ykfD - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
PFOHNOAK_02527 1.72e-214 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
PFOHNOAK_02528 1.68e-252 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
PFOHNOAK_02529 1.61e-225 ykfA 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
PFOHNOAK_02530 0.0 dppE - - E ko:K16199 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
PFOHNOAK_02531 9.2e-243 dppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
PFOHNOAK_02532 2.68e-226 dppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PFOHNOAK_02533 8.02e-204 dppB - - P ko:K16200 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PFOHNOAK_02534 4.36e-200 dppA - - E ko:K16203 - ko00000,ko01000,ko01002 D-aminopeptidase
PFOHNOAK_02535 0.0 yubD - - P - - - Major Facilitator Superfamily
PFOHNOAK_02536 3.06e-275 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PFOHNOAK_02538 5.21e-228 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
PFOHNOAK_02539 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
PFOHNOAK_02540 6.1e-228 ykcA - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
PFOHNOAK_02541 9.38e-312 steT - - E ko:K03294 - ko00000 amino acid
PFOHNOAK_02542 1.85e-144 ykaA - - P ko:K07220 - ko00000 COG1392 Phosphate transport regulator (distant homolog of PhoU)
PFOHNOAK_02543 7.07e-226 pit - - P ko:K03306 - ko00000 phosphate transporter
PFOHNOAK_02544 2.11e-169 spoIISA - - S ko:K06388 - ko00000 Toxin SpoIISA, type II toxin-antitoxin system
PFOHNOAK_02545 2.53e-31 spoIISB - - S ko:K06389 - ko00000 Stage II sporulation protein SB
PFOHNOAK_02546 6.03e-216 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
PFOHNOAK_02547 4.7e-52 xhlB - - S - - - SPP1 phage holin
PFOHNOAK_02548 3.87e-51 xhlA - - S - - - Haemolysin XhlA
PFOHNOAK_02549 2.12e-176 xepA - - - - - - -
PFOHNOAK_02550 1.55e-38 xkdX - - - - - - -
PFOHNOAK_02552 1.58e-85 - - - - - - - -
PFOHNOAK_02553 7.33e-37 - - - - - - - -
PFOHNOAK_02554 2.03e-112 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
PFOHNOAK_02555 1.08e-212 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
PFOHNOAK_02556 4.95e-77 xkdS - - S - - - Protein of unknown function (DUF2634)
PFOHNOAK_02557 2.51e-43 xkdR - - S - - - Protein of unknown function (DUF2577)
PFOHNOAK_02558 2.66e-206 xkdQ - - G - - - NLP P60 protein
PFOHNOAK_02559 6.56e-145 xkdP - - S - - - Lysin motif
PFOHNOAK_02560 4.59e-286 xkdO - - L - - - Transglycosylase SLT domain
PFOHNOAK_02561 4.33e-27 - - - - - - - -
PFOHNOAK_02562 7.28e-96 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
PFOHNOAK_02563 8.21e-97 xkdM - - S - - - Phage tail tube protein
PFOHNOAK_02564 2.82e-288 xkdK - - S - - - Phage tail sheath C-terminal domain
PFOHNOAK_02565 7.8e-21 - - - - - - - -
PFOHNOAK_02566 4.99e-73 xkdJ - - - - - - -
PFOHNOAK_02567 4.86e-77 xkdI - - S - - - Bacteriophage HK97-gp10, putative tail-component
PFOHNOAK_02568 2.02e-56 - - - S - - - Domain of unknown function (DUF3599)
PFOHNOAK_02569 4.38e-61 yqbG - - S - - - Protein of unknown function (DUF3199)
PFOHNOAK_02570 2.9e-203 xkdG - - S - - - Phage capsid family
PFOHNOAK_02571 5.26e-118 xkdF3 - - L - - - Putative phage serine protease XkdF
PFOHNOAK_02572 7.29e-303 xkdE3 - - S - - - portal protein
PFOHNOAK_02573 3.51e-265 xtmB - - S ko:K06909 - ko00000 phage terminase, large subunit
PFOHNOAK_02574 2.38e-140 xtmA - - L ko:K07474 - ko00000 phage terminase small subunit
PFOHNOAK_02575 2.15e-110 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
PFOHNOAK_02579 5.69e-192 xkdC - - L - - - Bacterial dnaA protein
PFOHNOAK_02581 6.52e-75 xre - - K - - - Helix-turn-helix XRE-family like proteins
PFOHNOAK_02582 7.61e-144 xkdA - - E - - - IrrE N-terminal-like domain
PFOHNOAK_02584 4.37e-141 yjqB - - S - - - phage-related replication protein
PFOHNOAK_02585 3.87e-80 yjqA - - S - - - Bacterial PH domain
PFOHNOAK_02586 8.26e-222 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
PFOHNOAK_02588 2.68e-275 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
PFOHNOAK_02589 1.19e-102 yjoA - - S - - - DinB family
PFOHNOAK_02590 1.86e-166 yjnA - - S ko:K07090 - ko00000 membrane transporter protein
PFOHNOAK_02591 6.49e-243 lcnDR2 - - V - - - Domain of unknown function (DUF4135)
PFOHNOAK_02594 3.9e-281 lanT - - V ko:K06148,ko:K13409,ko:K20344,ko:K20386 ko02010,ko02024,ko04626,map02010,map02024,map04626 ko00000,ko00001,ko00002,ko02000,ko02044 Peptidase C39 family
PFOHNOAK_02595 0.0 lcnDR2 - - V - - - Lanthionine synthetase C-like protein
PFOHNOAK_02597 4.43e-76 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PFOHNOAK_02598 1.85e-51 - 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PFOHNOAK_02600 1.03e-83 - - - S - - - ABC-2 family transporter protein
PFOHNOAK_02601 1.28e-131 - - - V ko:K01990,ko:K20459 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
PFOHNOAK_02602 1.05e-168 - - - T - - - HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
PFOHNOAK_02603 2.6e-112 - - - T - - - Transcriptional regulatory protein, C terminal
PFOHNOAK_02604 0.0 uxaA 4.2.1.7 - G ko:K01685 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
PFOHNOAK_02605 9.79e-233 exuR - - K ko:K02529 - ko00000,ko03000 transcriptional
PFOHNOAK_02606 0.0 - - - G ko:K03292 - ko00000 symporter YjmB
PFOHNOAK_02607 0.0 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
PFOHNOAK_02608 1.76e-279 yjlD 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
PFOHNOAK_02609 1.7e-87 yjlC - - S - - - Protein of unknown function (DUF1641)
PFOHNOAK_02610 3.49e-118 yjlB - - S - - - Cupin domain
PFOHNOAK_02611 1.32e-223 yjlA - - EG - - - Putative multidrug resistance efflux transporter
PFOHNOAK_02612 5.11e-165 yjkB - - P ko:K02068 - ko00000,ko00002,ko02000 Belongs to the ABC transporter superfamily
PFOHNOAK_02613 1.45e-158 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
PFOHNOAK_02614 5.13e-181 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
PFOHNOAK_02615 1.73e-40 - - - - - - - -
PFOHNOAK_02616 1.11e-281 yjiC - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
PFOHNOAK_02617 1.48e-287 yjiB 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
PFOHNOAK_02618 2.2e-117 yjgD - - S - - - Protein of unknown function (DUF1641)
PFOHNOAK_02619 0.0 - 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase, alpha subunit
PFOHNOAK_02620 1.6e-128 yjgB - - S - - - Domain of unknown function (DUF4309)
PFOHNOAK_02621 8.23e-88 yjgA - - T - - - Protein of unknown function (DUF2809)
PFOHNOAK_02622 7.78e-31 yjfB - - S - - - Putative motility protein
PFOHNOAK_02623 1.23e-136 - - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
PFOHNOAK_02625 2.21e-156 - - - S - - - Haloacid dehalogenase-like hydrolase
PFOHNOAK_02626 1.19e-178 yulB - - K ko:K02530 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
PFOHNOAK_02627 0.0 lacG 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
PFOHNOAK_02628 8.91e-67 celC 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
PFOHNOAK_02629 0.0 lacE 2.7.1.207 - G ko:K02761,ko:K02787,ko:K02788 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PFOHNOAK_02630 8.27e-272 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
PFOHNOAK_02631 9.12e-237 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
PFOHNOAK_02632 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
PFOHNOAK_02633 1.82e-279 yvfO 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
PFOHNOAK_02634 4.3e-106 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
PFOHNOAK_02635 8.76e-315 yfjF - - EGP - - - Belongs to the major facilitator superfamily
PFOHNOAK_02636 1.81e-60 yjcS - - S - - - Antibiotic biosynthesis monooxygenase
PFOHNOAK_02637 1.06e-206 penP 3.5.2.6 - V ko:K17836,ko:K18766 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 beta-lactamase
PFOHNOAK_02638 4.47e-76 - - - E - - - Glyoxalase-like domain
PFOHNOAK_02640 1.27e-93 - - - E - - - phosphoribosylanthranilate isomerase activity
PFOHNOAK_02641 8.36e-63 - - - FG ko:K02503 - ko00000,ko04147 Scavenger mRNA decapping enzyme C-term binding
PFOHNOAK_02643 2.61e-30 - - - - - - - -
PFOHNOAK_02644 0.000136 - - - T - - - Response regulator, receiver
PFOHNOAK_02646 2.06e-179 - - - I - - - Fatty acid desaturase
PFOHNOAK_02647 2.73e-91 argO - - S ko:K06895 - ko00000,ko02000 LysE type translocator
PFOHNOAK_02648 0.000336 - - - S - - - HIRAN domain
PFOHNOAK_02649 6.01e-89 yoaW - - - - - - -
PFOHNOAK_02650 1.33e-208 - - - S - - - Bacterial EndoU nuclease
PFOHNOAK_02651 7.58e-70 - - - - - - - -
PFOHNOAK_02653 5.42e-58 - - - S - - - Psort location Cytoplasmic, score
PFOHNOAK_02654 3.66e-25 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
PFOHNOAK_02656 3.29e-279 metC 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
PFOHNOAK_02657 2.18e-268 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
PFOHNOAK_02658 1.43e-163 yjcH - - P ko:K07214 - ko00000 COG2382 Enterochelin esterase and related enzymes
PFOHNOAK_02659 2.43e-121 yjcG - - J - - - Belongs to the 2H phosphoesterase superfamily. YjcG family
PFOHNOAK_02660 1.18e-94 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PFOHNOAK_02661 1.76e-47 - - - K - - - SpoVT / AbrB like domain
PFOHNOAK_02662 2.28e-167 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
PFOHNOAK_02663 1.26e-157 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
PFOHNOAK_02664 2.81e-179 blm 3.5.2.6 - S ko:K17837 ko01501,map01501 ko00000,ko00001,ko01000 Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
PFOHNOAK_02665 5e-48 - - - - - - - -
PFOHNOAK_02666 0.0 yjcD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
PFOHNOAK_02667 2.57e-51 spoVIF - - S - - - Stage VI sporulation protein F
PFOHNOAK_02671 2.05e-73 yjcA - - S - - - Protein of unknown function (DUF1360)
PFOHNOAK_02672 2.67e-68 cotV - - S ko:K06340 - ko00000 Spore Coat Protein X and V domain
PFOHNOAK_02673 8.38e-36 cotW - - - ko:K06341 - ko00000 -
PFOHNOAK_02674 2.61e-100 cotX - - S ko:K06342 - ko00000 Spore Coat Protein X and V domain
PFOHNOAK_02675 4.28e-121 cotY - - S ko:K06343 - ko00000 Spore coat protein Z
PFOHNOAK_02676 2.1e-108 cotZ - - S ko:K06344 - ko00000 Spore coat protein
PFOHNOAK_02677 3.38e-125 yjbX - - S - - - Spore coat protein
PFOHNOAK_02678 6.85e-180 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
PFOHNOAK_02679 3.03e-189 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
PFOHNOAK_02680 6.18e-238 thiF 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
PFOHNOAK_02681 7.36e-173 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
PFOHNOAK_02682 4.53e-41 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 Thiamine biosynthesis
PFOHNOAK_02683 3.08e-266 thiO 1.4.3.19, 1.4.5.1 - E ko:K00285,ko:K03153 ko00360,ko00730,ko01100,map00360,map00730,map01100 ko00000,ko00001,ko01000 Glycine oxidase
PFOHNOAK_02684 4.68e-138 tenI 5.3.99.10 - H ko:K10810 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Transcriptional regulator TenI
PFOHNOAK_02685 1.91e-175 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
PFOHNOAK_02686 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
PFOHNOAK_02687 5.9e-181 prpE 3.1.3.16, 3.6.1.41 - T ko:K01090,ko:K01525 ko00230,map00230 ko00000,ko00001,ko01000 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
PFOHNOAK_02688 5.76e-212 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
PFOHNOAK_02689 2.07e-194 nadK 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PFOHNOAK_02690 9.01e-139 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 GTP pyrophosphokinase
PFOHNOAK_02691 2.03e-80 yjbL - - S - - - Belongs to the UPF0738 family
PFOHNOAK_02692 3.34e-124 yjbK - - S - - - protein conserved in bacteria
PFOHNOAK_02693 3.49e-149 yjbJ - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
PFOHNOAK_02694 1.22e-93 yjbI - - S ko:K06886 - ko00000 Bacterial-like globin
PFOHNOAK_02695 1.73e-219 yjbH - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
PFOHNOAK_02696 3.14e-27 - - - - - - - -
PFOHNOAK_02697 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
PFOHNOAK_02698 2.49e-276 coiA - - S ko:K06198 - ko00000 Competence protein
PFOHNOAK_02699 9.78e-150 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
PFOHNOAK_02700 3.23e-140 yjbE - - P - - - Integral membrane protein TerC family
PFOHNOAK_02701 2.47e-88 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
PFOHNOAK_02702 7.3e-131 yjbC - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PFOHNOAK_02703 4.77e-293 - - - S - - - Putative glycosyl hydrolase domain
PFOHNOAK_02704 1.22e-217 oppF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
PFOHNOAK_02705 1.5e-256 oppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
PFOHNOAK_02706 5.09e-210 oppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PFOHNOAK_02707 2.53e-213 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PFOHNOAK_02708 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
PFOHNOAK_02709 1.45e-233 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
PFOHNOAK_02710 1.52e-188 yjbA - - S - - - Belongs to the UPF0736 family
PFOHNOAK_02711 7.81e-209 appC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PFOHNOAK_02712 4.24e-219 appB - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PFOHNOAK_02713 0.0 appA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
PFOHNOAK_02714 8.8e-239 appF - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
PFOHNOAK_02715 6.88e-231 appD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
PFOHNOAK_02716 1.84e-190 yjaZ - - O - - - Zn-dependent protease
PFOHNOAK_02717 3.86e-300 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
PFOHNOAK_02718 7.63e-220 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PFOHNOAK_02719 8.09e-44 yjzB - - - - - - -
PFOHNOAK_02720 6.46e-37 comZ - - S ko:K02254 - ko00000,ko02044 ComZ
PFOHNOAK_02721 2.22e-211 med - - S ko:K05519,ko:K07335 - ko00000,ko03000 Transcriptional activator protein med
PFOHNOAK_02722 6.81e-134 yjaV - - - - - - -
PFOHNOAK_02723 5.25e-177 yjaU - - I - - - carboxylic ester hydrolase activity
PFOHNOAK_02724 1.06e-32 yjzD - - S - - - Protein of unknown function (DUF2929)
PFOHNOAK_02725 7.21e-39 yjzC - - S - - - YjzC-like protein
PFOHNOAK_02726 1.43e-225 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
PFOHNOAK_02727 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase ammonia chain
PFOHNOAK_02728 3.83e-256 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
PFOHNOAK_02729 1.55e-274 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
PFOHNOAK_02730 5.17e-175 argB 2.7.2.8 - F ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
PFOHNOAK_02731 2.56e-290 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
PFOHNOAK_02732 5.84e-252 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
PFOHNOAK_02733 1.18e-121 yitZ - - G - - - Major Facilitator Superfamily
PFOHNOAK_02734 0.0 yitY - - C - - - D-arabinono-1,4-lactone oxidase
PFOHNOAK_02735 1.02e-95 fosB - - H ko:K11210,ko:K21252 - ko00000,ko01000,ko01504 Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
PFOHNOAK_02736 3.26e-68 yitW - - S - - - metal-sulfur cluster biosynthetic enzyme
PFOHNOAK_02737 1.24e-185 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
PFOHNOAK_02738 5.08e-197 - 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
PFOHNOAK_02739 1.49e-11 - - - - - - - -
PFOHNOAK_02740 1.5e-36 - - - S - - - Protein of unknown function (DUF3813)
PFOHNOAK_02741 1.51e-104 ipi - - S - - - Intracellular proteinase inhibitor
PFOHNOAK_02742 6.56e-189 yitT - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
PFOHNOAK_02743 5.06e-199 yitS - - S - - - protein conserved in bacteria
PFOHNOAK_02745 0.0 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
PFOHNOAK_02746 2.84e-217 - - - S ko:K07335 - ko00000 ABC transporter substrate-binding protein PnrA-like
PFOHNOAK_02747 4.36e-204 yitL - - S ko:K00243 - ko00000 protein conserved in bacteria
PFOHNOAK_02748 3.69e-78 yitK - - S ko:K09767 - ko00000 Belongs to the UPF0234 family
PFOHNOAK_02749 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
PFOHNOAK_02750 3.78e-106 - - - S - - - Acetyltransferase (GNAT) domain
PFOHNOAK_02751 2.62e-109 yisX - - S - - - Pentapeptide repeats (9 copies)
PFOHNOAK_02752 3.76e-108 yisT - - S - - - DinB family
PFOHNOAK_02753 9.41e-195 yisS 1.1.1.18, 1.1.1.369, 1.1.1.370 - S ko:K00010,ko:K16043 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
PFOHNOAK_02754 2.46e-182 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
PFOHNOAK_02755 6.43e-204 yisR - - K - - - Transcriptional regulator
PFOHNOAK_02756 2.14e-312 yisQ - - V - - - Mate efflux family protein
PFOHNOAK_02757 4.09e-166 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 phytoene
PFOHNOAK_02758 0.0 asnO 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
PFOHNOAK_02759 1.07e-123 yisN - - S - - - Protein of unknown function (DUF2777)
PFOHNOAK_02760 6.36e-78 yisL - - S - - - UPF0344 protein
PFOHNOAK_02761 1.04e-216 yisK - - Q - - - COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
PFOHNOAK_02762 1.03e-11 yisI - - S - - - Spo0E like sporulation regulatory protein
PFOHNOAK_02763 1.28e-45 gerPA - - S ko:K06299 - ko00000 Spore germination protein
PFOHNOAK_02764 3.82e-47 gerPB - - S ko:K06300 - ko00000 cell differentiation
PFOHNOAK_02765 8.51e-109 gerPC - - S ko:K06301 - ko00000 Spore germination protein
PFOHNOAK_02766 3e-33 gerPD - - S ko:K06302 - ko00000 Spore germination protein
PFOHNOAK_02767 1.61e-84 gerPE - - S ko:K06303 - ko00000 Spore germination protein GerPE
PFOHNOAK_02768 6.66e-43 gerPF - - S ko:K06299,ko:K06304 - ko00000 Spore germination protein gerPA/gerPF
PFOHNOAK_02769 2.64e-67 yisB - - V - - - COG1403 Restriction endonuclease
PFOHNOAK_02770 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 COG0419 ATPase involved in DNA repair
PFOHNOAK_02771 3.31e-283 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
PFOHNOAK_02772 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
PFOHNOAK_02773 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 ATP-dependent helicase deoxyribonuclease subunit B
PFOHNOAK_02774 1.52e-152 ydfS - - S - - - Protein of unknown function (DUF421)
PFOHNOAK_02775 1.47e-121 yhjR - - S - - - Rubrerythrin
PFOHNOAK_02776 3.71e-140 - - - K - - - QacR-like protein, C-terminal region
PFOHNOAK_02777 1.78e-266 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
PFOHNOAK_02778 5.69e-261 yhjN - - S ko:K07120 - ko00000 membrane
PFOHNOAK_02779 4.89e-122 yhjH - - K - - - helix_turn_helix multiple antibiotic resistance protein
PFOHNOAK_02780 0.0 yhjG - - CH - - - FAD binding domain
PFOHNOAK_02782 3.32e-119 spsB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
PFOHNOAK_02783 3.17e-142 yhjE - - S - - - SNARE associated Golgi protein
PFOHNOAK_02784 4.12e-79 yhjD - - - - - - -
PFOHNOAK_02785 5.59e-37 yhjC - - S - - - Protein of unknown function (DUF3311)
PFOHNOAK_02786 0.0 yhjB - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PFOHNOAK_02787 2.64e-63 - - - S - - - Belongs to the UPF0145 family
PFOHNOAK_02788 1.23e-57 yhjA - - S - - - Excalibur calcium-binding domain
PFOHNOAK_02789 1.49e-161 yrpD - - S - - - Domain of unknown function, YrpD
PFOHNOAK_02790 9.96e-82 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
PFOHNOAK_02791 3.48e-86 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
PFOHNOAK_02792 1.09e-141 comK - - K ko:K02250 ko02024,map02024 ko00000,ko00001,ko02044,ko03000 Competence transcription factor
PFOHNOAK_02793 3.87e-42 yhzC - - S - - - IDEAL
PFOHNOAK_02794 3.88e-204 yhxC - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PFOHNOAK_02795 0.0 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
PFOHNOAK_02796 3.24e-276 hemAT - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
PFOHNOAK_02797 7.56e-116 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
PFOHNOAK_02798 0.0 vraA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
PFOHNOAK_02799 2.48e-253 yhfS 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
PFOHNOAK_02800 4.96e-133 yhfR 5.4.2.12 - G ko:K15634,ko:K15640 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
PFOHNOAK_02801 1.73e-190 - - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
PFOHNOAK_02802 1.84e-260 aprE 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
PFOHNOAK_02803 1.24e-298 yhfN - - O - - - Peptidase M48
PFOHNOAK_02804 3.24e-84 yhfM - - - - - - -
PFOHNOAK_02805 0.0 yhfL 6.2.1.3 - IQ ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
PFOHNOAK_02806 5.81e-139 yhfK - - GM - - - NmrA-like family
PFOHNOAK_02807 1.85e-241 lplJ 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
PFOHNOAK_02808 5.69e-181 yhfI - - S - - - COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
PFOHNOAK_02810 3.43e-282 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
PFOHNOAK_02811 1.27e-251 yhfE - - G - - - peptidase M42
PFOHNOAK_02813 5.92e-235 fabHB 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PFOHNOAK_02814 0.0 yhgE - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
PFOHNOAK_02815 3.1e-131 yhgD - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
PFOHNOAK_02817 0.0 hemY 1.3.3.15, 1.3.3.4 - H ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
PFOHNOAK_02818 4.49e-232 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
PFOHNOAK_02819 1.73e-257 hemE 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
PFOHNOAK_02820 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
PFOHNOAK_02821 3.1e-117 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
PFOHNOAK_02822 1.39e-311 yhfA - - C - - - membrane
PFOHNOAK_02823 9.88e-283 yhaA - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
PFOHNOAK_02824 3.38e-159 ecsC - - S - - - EcsC protein family
PFOHNOAK_02825 1.29e-280 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
PFOHNOAK_02826 1.82e-174 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 transporter (ATP-binding protein)
PFOHNOAK_02827 8.27e-105 hit - - FG ko:K02503 - ko00000,ko04147 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
PFOHNOAK_02828 6.9e-258 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
PFOHNOAK_02829 8.25e-100 trpP - - S - - - Tryptophan transporter TrpP
PFOHNOAK_02830 2.55e-24 - - - - - - - -
PFOHNOAK_02831 1.36e-54 yhaH - - S - - - YtxH-like protein
PFOHNOAK_02832 8.17e-147 hpr - - K ko:K09682 - ko00000,ko03000 Negative regulator of protease production and sporulation
PFOHNOAK_02833 1.2e-72 yhaI - - S - - - Protein of unknown function (DUF1878)
PFOHNOAK_02834 1.29e-123 yhaK - - S - - - Putative zincin peptidase
PFOHNOAK_02835 1.53e-184 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
PFOHNOAK_02836 5.79e-43 yhaL - - S - - - Sporulation protein YhaL
PFOHNOAK_02837 2.48e-226 yhaM - - L ko:K03698 - ko00000,ko01000,ko03019 Shows a 3'-5' exoribonuclease activity
PFOHNOAK_02838 0.0 yhaN - - L - - - AAA domain
PFOHNOAK_02839 1.44e-297 yhaO - - L ko:K03547 - ko00000,ko03400 DNA repair exonuclease
PFOHNOAK_02840 8.35e-278 yhaP - - CP ko:K01992 - ko00000,ko00002,ko02000 COG1668 ABC-type Na efflux pump, permease component
PFOHNOAK_02841 5.34e-213 yhaQ - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
PFOHNOAK_02842 7.01e-20 - - - S - - - YhzD-like protein
PFOHNOAK_02843 6.81e-174 yhaR - - I - - - enoyl-CoA hydratase
PFOHNOAK_02845 8.88e-112 - - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
PFOHNOAK_02846 1.41e-266 yhaU - - P ko:K03455 - ko00000 COG0475 Kef-type K transport systems, membrane components
PFOHNOAK_02847 2.89e-316 - 1.14.13.59 - Q ko:K03897 ko00310,ko01120,map00310,map01120 ko00000,ko00001,ko01000 L-lysine 6-monooxygenase (NADPH-requiring)
PFOHNOAK_02848 0.0 hemZ - - H - - - coproporphyrinogen III oxidase
PFOHNOAK_02849 3.44e-204 yhaX - - S - - - haloacid dehalogenase-like hydrolase
PFOHNOAK_02850 5.35e-253 yhaZ - - L - - - DNA alkylation repair enzyme
PFOHNOAK_02851 3.3e-70 yheA - - S - - - Belongs to the UPF0342 family
PFOHNOAK_02852 3.19e-263 yheB - - S - - - Belongs to the UPF0754 family
PFOHNOAK_02853 2.55e-271 yheC - - HJ - - - YheC/D like ATP-grasp
PFOHNOAK_02854 0.0 yheD - - HJ - - - YheC/D like ATP-grasp
PFOHNOAK_02855 4.28e-49 yheE - - S - - - Family of unknown function (DUF5342)
PFOHNOAK_02856 3.3e-39 sspB - - S ko:K06418,ko:K06419 - ko00000 spore protein
PFOHNOAK_02858 6.68e-143 yheG - - GM - - - NAD(P)H-binding
PFOHNOAK_02859 0.0 yheH - - V ko:K18217,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
PFOHNOAK_02860 0.0 yheI - - V ko:K18216,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
PFOHNOAK_02862 7.15e-110 - - - T - - - universal stress protein
PFOHNOAK_02863 1.55e-123 ymcC - - S - - - Membrane
PFOHNOAK_02864 1e-113 pksA - - K - - - Transcriptional regulator
PFOHNOAK_02865 1.39e-196 dat 2.6.1.21 - E ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
PFOHNOAK_02866 4.69e-199 nodB1 - - G - - - deacetylase
PFOHNOAK_02867 1.19e-179 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
PFOHNOAK_02868 1.91e-261 yhdY - - M ko:K16052 - ko00000,ko02000 Mechanosensitive ion channel
PFOHNOAK_02869 1.45e-08 yhdX - - S - - - Uncharacterized protein YhdX
PFOHNOAK_02870 2.03e-162 yhdW 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
PFOHNOAK_02871 8.25e-78 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PFOHNOAK_02872 7.11e-71 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PFOHNOAK_02873 0.0 yhdT - - P - - - COG1253 Hemolysins and related proteins containing CBS domains
PFOHNOAK_02874 4.51e-300 - 2.3.1.179 - I ko:K00646,ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
PFOHNOAK_02875 2.01e-286 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
PFOHNOAK_02876 1.97e-92 cueR - - K ko:K11923 - ko00000,ko03000 transcriptional
PFOHNOAK_02877 3.94e-307 yhdP - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
PFOHNOAK_02878 8.84e-140 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
PFOHNOAK_02879 4.6e-113 sigM - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
PFOHNOAK_02880 1.69e-257 yhdL - - S - - - Sigma factor regulator N-terminal
PFOHNOAK_02881 8.62e-59 yhdK - - S - - - Sigma-M inhibitor protein
PFOHNOAK_02882 2.8e-265 yhdH - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
PFOHNOAK_02883 1.78e-316 yhdG - - E ko:K03294 - ko00000 amino acid
PFOHNOAK_02884 1.84e-204 yhdF - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PFOHNOAK_02885 9.08e-259 citA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
PFOHNOAK_02886 1.16e-208 citR - - K ko:K19242 - ko00000,ko03000 Transcriptional regulator
PFOHNOAK_02887 2.8e-171 lytE - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
PFOHNOAK_02888 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
PFOHNOAK_02889 0.0 spoVR - - S ko:K06415 - ko00000 Stage V sporulation protein R
PFOHNOAK_02890 0.0 ygxB - - M - - - Conserved TM helix
PFOHNOAK_02891 7.66e-96 nsrR - - K ko:K13771 ko05132,map05132 ko00000,ko00001,ko03000 Transcriptional regulator
PFOHNOAK_02892 1.91e-293 lytF - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
PFOHNOAK_02893 1.46e-71 yhdC - - S - - - Protein of unknown function (DUF3889)
PFOHNOAK_02894 6.98e-53 yhdB - - S - - - YhdB-like protein
PFOHNOAK_02895 4.84e-116 yhdA 1.7.1.6 - S ko:K03206 - ko00000,ko01000 NADPH-dependent FMN reductase
PFOHNOAK_02896 5.44e-144 yhcZ - - K ko:K02479 - ko00000,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PFOHNOAK_02897 3.98e-258 yhcY 2.7.13.3 - T ko:K02480 - ko00000,ko01000,ko01001,ko02022 Histidine kinase
PFOHNOAK_02898 0.0 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
PFOHNOAK_02899 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
PFOHNOAK_02900 0.0 glpK 2.7.1.30 - C ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PFOHNOAK_02901 2.32e-198 glpF - - G ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
PFOHNOAK_02902 8.57e-134 glpP - - K ko:K02443 - ko00000,ko03000 Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
PFOHNOAK_02903 0.0 yhxA - - E - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PFOHNOAK_02904 0.0 yhcX - - K - - - Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
PFOHNOAK_02905 1.39e-160 yhcW - - S ko:K07025 - ko00000 hydrolase
PFOHNOAK_02906 3.54e-90 yhcV - - S - - - COG0517 FOG CBS domain
PFOHNOAK_02907 1.88e-92 yhcU - - S - - - Family of unknown function (DUF5365)
PFOHNOAK_02908 3.09e-214 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
PFOHNOAK_02909 7.55e-136 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
PFOHNOAK_02910 0.0 yhcR 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01081,ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
PFOHNOAK_02911 7.38e-150 yhcQ - - M - - - Spore coat protein
PFOHNOAK_02912 1.68e-206 yhcP - - - - - - -
PFOHNOAK_02913 1.56e-121 yhcN - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
PFOHNOAK_02914 5.55e-76 yhcM - - - - - - -
PFOHNOAK_02915 7.04e-306 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
PFOHNOAK_02916 1.43e-234 yhcK 2.7.7.65 - T ko:K18967 - ko00000,ko01000,ko02000 COG2199 FOG GGDEF domain
PFOHNOAK_02917 4.43e-185 metQ_3 - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
PFOHNOAK_02918 7.28e-42 cspB - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
PFOHNOAK_02919 1.29e-208 yhcI - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
PFOHNOAK_02920 9.59e-215 yhcH - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
PFOHNOAK_02921 2.32e-158 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
PFOHNOAK_02922 1.35e-80 yhcF - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator
PFOHNOAK_02923 9.36e-66 - - - - - - - -
PFOHNOAK_02924 1.41e-72 yhcC - - - - - - -
PFOHNOAK_02925 9.09e-129 wrbA 1.6.5.2 - S ko:K03809 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
PFOHNOAK_02926 0.0 yhcA - - EGP ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
PFOHNOAK_02927 1.54e-132 yhbJ - - V - - - COG1566 Multidrug resistance efflux pump
PFOHNOAK_02928 4.15e-98 yhbI - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
PFOHNOAK_02929 5.45e-279 yhbH - - S ko:K09786 - ko00000 Belongs to the UPF0229 family
PFOHNOAK_02930 0.0 prkA - - T ko:K07180 - ko00000 Ser protein kinase
PFOHNOAK_02931 1.23e-07 - - - - - - - -
PFOHNOAK_02932 3.84e-92 yhbF - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
PFOHNOAK_02933 1.87e-83 yhbE - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
PFOHNOAK_02934 1.62e-139 yhbD - - K - - - Protein of unknown function (DUF4004)
PFOHNOAK_02935 4.84e-112 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
PFOHNOAK_02936 1.11e-220 yhbB - - S - - - Putative amidase domain
PFOHNOAK_02937 6.66e-284 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
PFOHNOAK_02938 3.29e-139 yhzB - - S - - - B3/4 domain
PFOHNOAK_02940 9.41e-32 - - - K ko:K07729 - ko00000,ko03000 Transcriptional regulator
PFOHNOAK_02941 1.83e-106 ygaO - - - - - - -
PFOHNOAK_02942 1.83e-53 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PFOHNOAK_02943 1.22e-272 ssuD 1.14.14.28, 1.14.14.5 - C ko:K04091,ko:K20938 ko00920,map00920 ko00000,ko00001,ko01000 Catalyzes the desulfonation of aliphatic sulfonates
PFOHNOAK_02944 1.95e-184 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
PFOHNOAK_02945 1.01e-228 ssuA - - M ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Sulfonate ABC transporter
PFOHNOAK_02946 2.6e-179 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
PFOHNOAK_02947 8.69e-230 - - - S ko:K07045 - ko00000 Amidohydrolase
PFOHNOAK_02948 0.0 katA 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
PFOHNOAK_02949 1.9e-167 oppF9 - - E ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
PFOHNOAK_02950 1.34e-170 oppD3 - - P ko:K02031 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
PFOHNOAK_02951 8.8e-162 - - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PFOHNOAK_02952 5.79e-179 - - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PFOHNOAK_02953 2.86e-294 oppA5 - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 PFAM extracellular solute-binding protein family 5
PFOHNOAK_02955 0.0 ygaK - - C - - - Berberine and berberine like
PFOHNOAK_02956 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
PFOHNOAK_02957 2.06e-168 ygaJ 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
PFOHNOAK_02958 1.49e-25 - - - C - - - Na+/H+ antiporter family
PFOHNOAK_02975 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
PFOHNOAK_02976 1.59e-212 ygxA - - S - - - Nucleotidyltransferase-like
PFOHNOAK_02977 4.67e-75 ygzB - - S - - - UPF0295 protein
PFOHNOAK_02978 2.37e-104 perR - - P ko:K09825 - ko00000,ko03000 Belongs to the Fur family
PFOHNOAK_02979 1.39e-111 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Peroxiredoxin
PFOHNOAK_02980 6.86e-314 gsaB 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
PFOHNOAK_02981 5.27e-239 ygaE - - S - - - Membrane
PFOHNOAK_02982 0.0 ygaD - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
PFOHNOAK_02983 2.32e-135 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
PFOHNOAK_02984 1.4e-49 ygaB - - S - - - YgaB-like protein
PFOHNOAK_02985 4.77e-06 sspE - - S ko:K06422 - ko00000 Small, acid-soluble spore protein, gamma-type
PFOHNOAK_02986 3.81e-173 fabL 1.3.1.104 - IQ ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PFOHNOAK_02987 1.47e-49 yfhS - - - - - - -
PFOHNOAK_02988 1.64e-261 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific
PFOHNOAK_02989 2.94e-236 yfhP - - S ko:K07038 - ko00000 membrane-bound metal-dependent
PFOHNOAK_02990 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
PFOHNOAK_02991 1.35e-236 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
PFOHNOAK_02992 9.27e-217 - - - S - - - Alpha/beta hydrolase family
PFOHNOAK_02993 6.03e-57 yfhL - - S - - - SdpI/YhfL protein family
PFOHNOAK_02994 3.29e-121 yfhK - - T - - - Bacterial SH3 domain homologues
PFOHNOAK_02995 2.57e-59 yfhJ - - S - - - WVELL protein
PFOHNOAK_02996 2.02e-215 mpr - - M - - - Belongs to the peptidase S1B family
PFOHNOAK_02998 2.25e-265 yfhI - - EGP - - - -transporter
PFOHNOAK_02999 3.1e-69 yfhH - - S - - - Protein of unknown function (DUF1811)
PFOHNOAK_03000 5.21e-182 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
PFOHNOAK_03001 1.42e-213 yfhF - - S ko:K07071 - ko00000 nucleoside-diphosphate sugar epimerase
PFOHNOAK_03003 3.61e-34 yfhD - - S - - - YfhD-like protein
PFOHNOAK_03004 4.76e-137 yfhC - - C - - - nitroreductase
PFOHNOAK_03005 1.91e-204 yfhB - - S - - - PhzF family
PFOHNOAK_03006 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PFOHNOAK_03007 2.29e-107 yfiV - - K - - - transcriptional
PFOHNOAK_03008 0.0 yfiU - - EGP - - - the major facilitator superfamily
PFOHNOAK_03009 1.05e-124 yfiT - - S - - - Belongs to the metal hydrolase YfiT family
PFOHNOAK_03010 1.66e-60 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
PFOHNOAK_03011 0.0 - 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
PFOHNOAK_03012 1.48e-233 yfiQ - - G ko:K21462 - ko00000 COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
PFOHNOAK_03013 3.47e-142 - 1.6.5.2 - S ko:K00355 ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
PFOHNOAK_03014 1.88e-124 padR - - K - - - transcriptional
PFOHNOAK_03015 4.69e-211 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
PFOHNOAK_03016 1.58e-203 yfiE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
PFOHNOAK_03017 7.86e-82 yfiD3 - - S - - - DoxX
PFOHNOAK_03018 0.0 yfiC3 - - V ko:K06147 - ko00000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
PFOHNOAK_03019 0.0 yfiB3 - - V ko:K06147 - ko00000,ko02000 ABC transporter
PFOHNOAK_03020 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
PFOHNOAK_03021 4.47e-178 glvR - - F ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
PFOHNOAK_03022 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
PFOHNOAK_03023 6.64e-22 sspH - - S ko:K06425 - ko00000 Belongs to the SspH family
PFOHNOAK_03024 0.0 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
PFOHNOAK_03025 0.0 acoL 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
PFOHNOAK_03026 5.38e-272 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
PFOHNOAK_03027 1.78e-240 acoB - - C ko:K21417 - ko00000,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
PFOHNOAK_03028 5.55e-244 acoA - - C ko:K21416 - ko00000,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
PFOHNOAK_03029 5.06e-112 yfjM - - S - - - Psort location Cytoplasmic, score
PFOHNOAK_03030 4.22e-245 yfjN - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PFOHNOAK_03031 4.14e-59 - - - S - - - YfzA-like protein
PFOHNOAK_03032 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PFOHNOAK_03033 9.93e-208 yfjP 3.2.2.21 - L ko:K01247 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
PFOHNOAK_03034 2.61e-235 corA - - P ko:K03284 - ko00000,ko02000 Mediates influx of magnesium ions
PFOHNOAK_03036 1.27e-189 yfjR - - I - - - NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
PFOHNOAK_03037 4.36e-199 pdaA - - G ko:K01567 - ko00000,ko01000 deacetylase
PFOHNOAK_03038 7.99e-37 yfjT - - - - - - -
PFOHNOAK_03039 1.14e-279 yfkA - - S - - - YfkB-like domain
PFOHNOAK_03040 4.1e-186 yfkC - - M - - - Mechanosensitive ion channel
PFOHNOAK_03041 1.33e-184 yfkD - - S - - - YfkD-like protein
PFOHNOAK_03042 1.7e-238 cax - - P ko:K07300 - ko00000,ko02000 COG0387 Ca2 H antiporter
PFOHNOAK_03043 5.89e-278 yfkF - - EGP - - - COG0477 Permeases of the major facilitator superfamily
PFOHNOAK_03044 6.71e-12 - - - - - - - -
PFOHNOAK_03045 1.6e-184 yihY - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
PFOHNOAK_03046 2.14e-69 yfkI - - S - - - gas vesicle protein
PFOHNOAK_03047 6.88e-112 yfkJ 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PFOHNOAK_03048 1.47e-41 yfkK - - S - - - Belongs to the UPF0435 family
PFOHNOAK_03049 3.85e-249 - - - EGP - - - COG0477 Permeases of the major facilitator superfamily
PFOHNOAK_03050 2.04e-174 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
PFOHNOAK_03051 1.01e-208 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PFOHNOAK_03052 1.51e-237 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
PFOHNOAK_03053 7.82e-118 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
PFOHNOAK_03054 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
PFOHNOAK_03055 1.42e-251 yibE - - S - - - YibE/F-like protein
PFOHNOAK_03056 2.01e-165 yibF - - S - - - YibE/F-like protein
PFOHNOAK_03057 1.45e-158 frp - - C - - - nitroreductase
PFOHNOAK_03058 3.14e-166 treR - - K ko:K03486 - ko00000,ko03000 transcriptional
PFOHNOAK_03059 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
PFOHNOAK_03060 4.49e-313 treP 2.7.1.201 - G ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
PFOHNOAK_03061 1.85e-53 ydgB - - S - - - Spore germination protein gerPA/gerPF
PFOHNOAK_03062 8.17e-52 ydgA - - S - - - Spore germination protein gerPA/gerPF
PFOHNOAK_03063 7.11e-105 cotP - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
PFOHNOAK_03064 4.9e-83 ydhN1 - - S - - - Domain of unknown function (DUF1992)
PFOHNOAK_03065 0.0 yflE 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
PFOHNOAK_03066 1.17e-96 yfmQ - - S - - - Uncharacterised protein from bacillus cereus group
PFOHNOAK_03067 0.0 nagE 2.7.1.193, 2.7.1.199 - G ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
PFOHNOAK_03068 1.9e-177 yflG 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
PFOHNOAK_03069 1.67e-66 yflH - - S - - - Protein of unknown function (DUF3243)
PFOHNOAK_03070 1.98e-26 yflI - - - - - - -
PFOHNOAK_03071 5.84e-21 yflJ - - S - - - Protein of unknown function (DUF2639)
PFOHNOAK_03072 2.51e-158 yflK - - S - - - protein conserved in bacteria
PFOHNOAK_03073 3.93e-59 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
PFOHNOAK_03074 3.37e-276 nos 1.14.14.47 - C ko:K00491 ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the NOS family. Bacterial NOS oxygenase subfamily
PFOHNOAK_03075 8.08e-191 yflN - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
PFOHNOAK_03076 2.35e-286 citM - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
PFOHNOAK_03077 7.99e-226 yflP - - S - - - Tripartite tricarboxylate transporter family receptor
PFOHNOAK_03078 9.33e-153 citT - - T ko:K11638 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
PFOHNOAK_03079 0.0 citS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
PFOHNOAK_03081 7.54e-07 - - - S - - - domain, Protein
PFOHNOAK_03087 0.0 yflS - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
PFOHNOAK_03088 1.6e-308 pel 4.2.2.2 - G ko:K01728 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
PFOHNOAK_03089 4.9e-76 yflT - - S - - - Heat induced stress protein YflT
PFOHNOAK_03090 1.04e-31 - - - S - - - Protein of unknown function (DUF3212)
PFOHNOAK_03091 1.35e-238 yfmJ - - S ko:K07119 - ko00000 N-terminal domain of oxidoreductase
PFOHNOAK_03092 2.31e-83 yfmK 2.3.1.128 - K ko:K03790 - ko00000,ko01000,ko03009 acetyltransferase
PFOHNOAK_03093 2.42e-262 yfmL - - L - - - COG0513 Superfamily II DNA and RNA helicases
PFOHNOAK_03094 0.0 yheS_1 - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
PFOHNOAK_03095 1.39e-261 yfmO - - EGP ko:K08221 - ko00000,ko02000 Major facilitator superfamily
PFOHNOAK_03096 8.7e-91 yfmP - - K ko:K21902 - ko00000,ko03000 transcriptional
PFOHNOAK_03097 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 COG0488 ATPase components of ABC transporters with duplicated ATPase domains
PFOHNOAK_03098 1.64e-263 - - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
PFOHNOAK_03099 8.54e-215 yhxD - - IQ - - - Enoyl-(Acyl carrier protein) reductase
PFOHNOAK_03100 5.49e-167 yfmS - - NT - - - chemotaxis protein
PFOHNOAK_03101 0.0 yfmT 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
PFOHNOAK_03102 3.41e-312 yfnA - - E ko:K03294 - ko00000 amino acid
PFOHNOAK_03103 6.35e-277 fsr - - P ko:K08223 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
PFOHNOAK_03104 8.13e-238 yfnD - - M - - - Nucleotide-diphospho-sugar transferase
PFOHNOAK_03105 4.01e-282 yfnE - - S - - - Glycosyltransferase like family 2
PFOHNOAK_03106 6.61e-230 yfnF - - M - - - Nucleotide-diphospho-sugar transferase
PFOHNOAK_03107 6.8e-220 yfnG 4.2.1.45, 4.2.1.46 - M ko:K01709,ko:K01710 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 dehydratase
PFOHNOAK_03108 1.02e-188 yfnH 2.7.7.33 - JM ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 ko00000,ko00001,ko01000 Nucleotidyl transferase
PFOHNOAK_03109 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
PFOHNOAK_03110 0.0 cypD 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
PFOHNOAK_03111 2.38e-252 yetN - - S - - - Protein of unknown function (DUF3900)
PFOHNOAK_03112 5.52e-261 yetM - - CH - - - FAD binding domain
PFOHNOAK_03113 1.92e-113 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
PFOHNOAK_03114 7.32e-135 yetJ - - S ko:K06890 - ko00000 Belongs to the BI1 family
PFOHNOAK_03115 3.68e-73 - - - H - - - riboflavin kinase activity
PFOHNOAK_03116 5.48e-31 - - - S - - - Uncharacterized small protein (DUF2292)
PFOHNOAK_03117 3.63e-196 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
PFOHNOAK_03118 2.66e-85 yetH - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PFOHNOAK_03119 1.11e-72 yetG 1.14.99.48 - S ko:K07145 ko00860,ko01110,map00860,map01110 ko00000,ko00001,ko01000 Antibiotic biosynthesis monooxygenase
PFOHNOAK_03120 8.62e-155 yetF - - S - - - membrane
PFOHNOAK_03121 5.92e-05 - - - - - - - -
PFOHNOAK_03122 1.15e-122 yesJ - - K - - - Acetyltransferase (GNAT) family
PFOHNOAK_03123 1.48e-133 cotJC - - P ko:K06334 - ko00000 Spore Coat
PFOHNOAK_03124 9.4e-61 cotJB - - S ko:K06333 - ko00000 CotJB protein
PFOHNOAK_03125 2.67e-60 cotJA - - S ko:K06332 - ko00000 Spore coat associated protein JA (CotJA)
PFOHNOAK_03126 1.02e-133 aadK - - G ko:K05593 - ko00000,ko01000,ko01504 Streptomycin adenylyltransferase
PFOHNOAK_03128 3.12e-162 yeeN - - K - - - transcriptional regulatory protein
PFOHNOAK_03129 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 nucleic acid phosphodiester bond hydrolysis
PFOHNOAK_03130 2.48e-66 - - - S - - - Protein of unknown function, DUF600
PFOHNOAK_03131 9.65e-67 - - - S - - - Protein of unknown function, DUF600
PFOHNOAK_03132 9.7e-26 - - - S - - - Protein of unknown function, DUF600
PFOHNOAK_03133 3.88e-23 - - - S - - - Protein of unknown function, DUF600
PFOHNOAK_03135 0.0 sthIR 3.1.21.5 - S ko:K01156 - ko00000,ko01000,ko02048 Type III restriction
PFOHNOAK_03136 4.74e-228 mod 2.1.1.72 - L ko:K00571,ko:K07316 - ko00000,ko01000,ko02048 Adenine specific DNA methylase Mod
PFOHNOAK_03137 0.0 rlmCD 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PFOHNOAK_03138 4.24e-217 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
PFOHNOAK_03139 0.0 swrC - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PFOHNOAK_03140 4.13e-193 yerO - - K - - - Transcriptional regulator
PFOHNOAK_03141 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PFOHNOAK_03142 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
PFOHNOAK_03143 1.81e-60 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PFOHNOAK_03144 0.0 putP - - E ko:K03307,ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PFOHNOAK_03145 1.68e-157 sapB - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
PFOHNOAK_03146 3.9e-243 yerI - - S - - - homoserine kinase type II (protein kinase fold)
PFOHNOAK_03147 6.46e-285 camS - - S - - - COG4851 Protein involved in sex pheromone biosynthesis
PFOHNOAK_03148 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PFOHNOAK_03149 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
PFOHNOAK_03150 8.71e-164 pcrB - - I ko:K07094 - ko00000,ko01000 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
PFOHNOAK_03151 0.0 yerD 1.4.7.1 - E ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 ko00000,ko00001,ko01000 Belongs to the glutamate synthase family
PFOHNOAK_03152 2.03e-67 yerC - - S - - - protein conserved in bacteria
PFOHNOAK_03153 6.02e-247 yerB - - S - - - Protein of unknown function (DUF3048) C-terminal domain
PFOHNOAK_03154 0.0 yerA 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 adenine deaminase
PFOHNOAK_03155 1.2e-33 - - - S - - - Protein of unknown function (DUF2892)
PFOHNOAK_03156 2.32e-297 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
PFOHNOAK_03157 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
PFOHNOAK_03158 9.96e-135 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PFOHNOAK_03159 1.46e-241 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
PFOHNOAK_03160 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PFOHNOAK_03161 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PFOHNOAK_03162 1.34e-166 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PFOHNOAK_03163 3.79e-52 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PFOHNOAK_03164 3.96e-165 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
PFOHNOAK_03165 6.38e-315 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PFOHNOAK_03166 4.56e-287 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PFOHNOAK_03167 3.78e-107 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PFOHNOAK_03168 6.56e-40 yebG - - S - - - NETI protein
PFOHNOAK_03169 1.21e-118 yebE - - S - - - UPF0316 protein
PFOHNOAK_03171 6.19e-168 yebC - - M - - - Membrane
PFOHNOAK_03172 1.75e-269 pbuG - - S ko:K06901 - ko00000,ko02000 permease
PFOHNOAK_03173 4.51e-315 - - - S - - - Domain of unknown function (DUF4179)
PFOHNOAK_03174 4.67e-122 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
PFOHNOAK_03175 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
PFOHNOAK_03176 0.0 yebA - - E - - - COG1305 Transglutaminase-like enzymes
PFOHNOAK_03177 1.25e-265 yeaD - - S - - - conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
PFOHNOAK_03178 2.29e-225 yeaC - - S ko:K03924 - ko00000,ko01000 COG0714 MoxR-like ATPases
PFOHNOAK_03179 4.33e-315 gabP - - E ko:K11735 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
PFOHNOAK_03180 0.0 cotA 1.16.3.3 - Q ko:K06324 - ko00000,ko01000 multicopper oxidases
PFOHNOAK_03181 2.02e-47 ydjO - - S - - - Cold-inducible protein YdjO
PFOHNOAK_03183 2.74e-192 ydjN - - U - - - Involved in the tonB-independent uptake of proteins
PFOHNOAK_03184 6.51e-82 ydjM - - M - - - Lytic transglycolase
PFOHNOAK_03185 8.25e-248 ydjL 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
PFOHNOAK_03186 1.87e-113 sigV - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
PFOHNOAK_03187 3.25e-192 rsiV - - S - - - Protein of unknown function (DUF3298)
PFOHNOAK_03188 0.0 oatA - - I - - - Acyltransferase family
PFOHNOAK_03189 4.85e-202 ydjI - - S - - - virion core protein (lumpy skin disease virus)
PFOHNOAK_03190 8.73e-160 ydjH - - S ko:K06872 - ko00000 COG1512 Beta-propeller domains of methanol dehydrogenase type
PFOHNOAK_03191 6.3e-229 ydjG - - L - - - Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PFOHNOAK_03192 3.2e-145 pspA - - KT ko:K03969 - ko00000 Phage shock protein A
PFOHNOAK_03193 1.47e-40 yjdJ - - S - - - Domain of unknown function (DUF4306)
PFOHNOAK_03194 1.42e-219 ydjE 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
PFOHNOAK_03195 1.18e-315 gutP - - G ko:K03292,ko:K16248 - ko00000,ko02000 MFS/sugar transport protein
PFOHNOAK_03196 2.05e-256 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
PFOHNOAK_03197 0.0 gutR - - K ko:K16247 - ko00000,ko03000 NB-ARC domain
PFOHNOAK_03198 5.42e-82 - - - - - - - -
PFOHNOAK_03201 0.0 ykuG - - M - - - Putative peptidoglycan binding domain
PFOHNOAK_03202 2.38e-23 - - - - - - - -
PFOHNOAK_03203 3.45e-118 - - - - - - - -
PFOHNOAK_03204 1.5e-76 - - - S - - - guanosine tetraphosphate metabolic process
PFOHNOAK_03205 3.48e-156 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
PFOHNOAK_03206 3.33e-78 - - - S - - - Pfam:Phage_holin_4_1
PFOHNOAK_03210 2.44e-243 - - - L - - - Phage minor structural protein
PFOHNOAK_03212 2.41e-171 - - - - - - - -
PFOHNOAK_03215 1.31e-38 - - - S - - - Phage tail tube protein
PFOHNOAK_03216 1.99e-38 - - - S - - - Protein of unknown function (DUF3168)
PFOHNOAK_03217 1.11e-50 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
PFOHNOAK_03218 8.56e-37 - - - S - - - Phage head-tail joining protein
PFOHNOAK_03219 1.06e-36 - - - S - - - Phage gp6-like head-tail connector protein
PFOHNOAK_03221 2.5e-05 - - - - - - - -
PFOHNOAK_03222 3.34e-179 - - - S - - - Phage capsid family
PFOHNOAK_03223 1.19e-79 - - - S - - - Domain of unknown function (DUF4355)
PFOHNOAK_03225 2.17e-116 - - - S - - - Phage Mu protein F like protein
PFOHNOAK_03226 3.01e-253 - - - S - - - Phage portal protein, SPP1 Gp6-like
PFOHNOAK_03227 1.18e-234 - - - S - - - Terminase-like family
PFOHNOAK_03228 2.1e-105 yqaS - - L - - - DNA packaging
PFOHNOAK_03230 1.74e-17 - - - K - - - Transcriptional regulator
PFOHNOAK_03232 2.39e-87 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
PFOHNOAK_03234 8.93e-61 - - - - - - - -
PFOHNOAK_03238 0.000217 - - - S - - - YopX protein
PFOHNOAK_03240 7.91e-58 - - - S - - - dUTPase
PFOHNOAK_03243 6.55e-89 - - - - - - - -
PFOHNOAK_03245 1.74e-10 - - - - - - - -
PFOHNOAK_03247 8.19e-24 yqaO - - S - - - Phage-like element PBSX protein XtrA
PFOHNOAK_03249 2.59e-70 - - - S - - - Protein of unknown function (DUF1064)
PFOHNOAK_03250 1.66e-42 - - - S - - - YopX protein
PFOHNOAK_03252 3.67e-155 yqaM - - L - - - IstB-like ATP binding protein
PFOHNOAK_03253 5.04e-35 yqaL - - L - - - DnaD domain protein
PFOHNOAK_03255 4.45e-88 pi112 - - L - - - PDDEXK-like domain of unknown function (DUF3799)
PFOHNOAK_03256 1.19e-124 - - - - - - - -
PFOHNOAK_03260 3.27e-110 - - - - - - - -
PFOHNOAK_03261 5.42e-50 - - - S - - - DNA binding
PFOHNOAK_03262 3.99e-32 - - - - - - - -
PFOHNOAK_03263 5.22e-18 - - - K - - - Helix-turn-helix XRE-family like proteins
PFOHNOAK_03264 3.22e-21 - - - K - - - Helix-turn-helix XRE-family like proteins
PFOHNOAK_03265 1.63e-45 - - - S - - - Domain of unknown function (DUF4352)
PFOHNOAK_03266 1.84e-35 xkdA - - E - - - IrrE N-terminal-like domain
PFOHNOAK_03267 7.01e-51 - - - L - - - Belongs to the 'phage' integrase family
PFOHNOAK_03268 2.38e-23 - - - - - - - -
PFOHNOAK_03269 3.45e-118 - - - - - - - -
PFOHNOAK_03270 1.5e-76 - - - S - - - guanosine tetraphosphate metabolic process
PFOHNOAK_03271 3.48e-156 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
PFOHNOAK_03272 3.33e-78 - - - S - - - Pfam:Phage_holin_4_1
PFOHNOAK_03276 2.44e-243 - - - L - - - Phage minor structural protein
PFOHNOAK_03278 2.41e-171 - - - - - - - -
PFOHNOAK_03281 1.31e-38 - - - S - - - Phage tail tube protein
PFOHNOAK_03282 1.99e-38 - - - S - - - Protein of unknown function (DUF3168)
PFOHNOAK_03283 1.11e-50 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
PFOHNOAK_03284 8.56e-37 - - - S - - - Phage head-tail joining protein
PFOHNOAK_03285 1.06e-36 - - - S - - - Phage gp6-like head-tail connector protein
PFOHNOAK_03287 2.5e-05 - - - - - - - -
PFOHNOAK_03288 3.34e-179 - - - S - - - Phage capsid family
PFOHNOAK_03289 1.19e-79 - - - S - - - Domain of unknown function (DUF4355)
PFOHNOAK_03291 2.17e-116 - - - S - - - Phage Mu protein F like protein
PFOHNOAK_03292 3.01e-253 - - - S - - - Phage portal protein, SPP1 Gp6-like
PFOHNOAK_03293 1.18e-234 - - - S - - - Terminase-like family
PFOHNOAK_03294 2.1e-105 yqaS - - L - - - DNA packaging
PFOHNOAK_03296 1.74e-17 - - - K - - - Transcriptional regulator
PFOHNOAK_03298 2.39e-87 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
PFOHNOAK_03300 8.93e-61 - - - - - - - -
PFOHNOAK_03304 0.000217 - - - S - - - YopX protein
PFOHNOAK_03306 7.91e-58 - - - S - - - dUTPase
PFOHNOAK_03309 7.71e-85 - - - - - - - -
PFOHNOAK_03311 8.19e-24 yqaO - - S - - - Phage-like element PBSX protein XtrA
PFOHNOAK_03313 2.59e-70 - - - S - - - Protein of unknown function (DUF1064)
PFOHNOAK_03314 1.66e-42 - - - S - - - YopX protein
PFOHNOAK_03316 3.67e-155 yqaM - - L - - - IstB-like ATP binding protein
PFOHNOAK_03317 5.04e-35 yqaL - - L - - - DnaD domain protein
PFOHNOAK_03319 4.45e-88 pi112 - - L - - - PDDEXK-like domain of unknown function (DUF3799)
PFOHNOAK_03320 1.19e-124 - - - - - - - -
PFOHNOAK_03324 3.27e-110 - - - - - - - -
PFOHNOAK_03325 5.42e-50 - - - S - - - DNA binding
PFOHNOAK_03326 3.99e-32 - - - - - - - -
PFOHNOAK_03327 5.22e-18 - - - K - - - Helix-turn-helix XRE-family like proteins
PFOHNOAK_03328 3.22e-21 - - - K - - - Helix-turn-helix XRE-family like proteins
PFOHNOAK_03329 1.63e-45 - - - S - - - Domain of unknown function (DUF4352)
PFOHNOAK_03330 1.84e-35 xkdA - - E - - - IrrE N-terminal-like domain
PFOHNOAK_03331 7.01e-51 - - - L - - - Belongs to the 'phage' integrase family
PFOHNOAK_03332 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
PFOHNOAK_03333 2.14e-58 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PFOHNOAK_03334 8.26e-165 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
PFOHNOAK_03335 1.11e-37 ydiK - - S - - - Domain of unknown function (DUF4305)
PFOHNOAK_03336 3.33e-162 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PFOHNOAK_03337 1.72e-29 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
PFOHNOAK_03338 5.25e-149 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
PFOHNOAK_03339 2.95e-117 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
PFOHNOAK_03340 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter
PFOHNOAK_03341 5.11e-242 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PFOHNOAK_03342 1.65e-107 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
PFOHNOAK_03343 2.8e-160 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214 Inactive homolog of metal-dependent proteases
PFOHNOAK_03344 7.42e-112 ydiB - - S ko:K06925 - ko00000,ko03016 ATPase or kinase
PFOHNOAK_03345 8.41e-235 thiL 2.7.4.16 - H ko:K00946 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
PFOHNOAK_03348 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
PFOHNOAK_03351 0.0 iolT - - U ko:K02100,ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
PFOHNOAK_03352 3.16e-234 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Quinone oxidoreductase
PFOHNOAK_03353 2.7e-110 yndB - - S - - - Activator of Hsp90 ATPase homolog 1-like protein
PFOHNOAK_03354 9.97e-211 ydhU - - P ko:K07217 - ko00000 Catalase
PFOHNOAK_03355 0.0 ybeC - - E - - - amino acid
PFOHNOAK_03356 4.95e-134 yvdT_1 - - K - - - Transcriptional regulator
PFOHNOAK_03357 4.48e-67 yvdS - - P ko:K18924 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
PFOHNOAK_03358 1.48e-65 yvdR - - P ko:K11741 - ko00000,ko02000 Small Multidrug Resistance protein
PFOHNOAK_03359 2.04e-275 yycB1 - - P ko:K03449 - ko00000,ko02000 COG2807 Cyanate permease
PFOHNOAK_03360 1.09e-152 - - - K ko:K05799 - ko00000,ko03000 FCD
PFOHNOAK_03361 3.41e-170 ydhQ - - K ko:K03492 - ko00000,ko03000 UTRA
PFOHNOAK_03362 2.24e-247 ydhL - - EGP ko:K18567 - ko00000,ko02000 COG2814 Arabinose efflux permease
PFOHNOAK_03363 6.11e-128 ydhK - - M - - - Protein of unknown function (DUF1541)
PFOHNOAK_03365 0.0 pbpE - - V - - - Beta-lactamase
PFOHNOAK_03368 4.58e-289 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
PFOHNOAK_03369 7.66e-153 ydhC - - K - - - FCD
PFOHNOAK_03370 1.02e-210 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Isocitrate/isopropylmalate dehydrogenase
PFOHNOAK_03371 1.1e-186 - - - Q - - - ubiE/COQ5 methyltransferase family
PFOHNOAK_03372 6.18e-143 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
PFOHNOAK_03373 5.16e-191 gmT1 - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
PFOHNOAK_03374 1.39e-191 bltR - - K - - - helix_turn_helix, mercury resistance
PFOHNOAK_03375 7.23e-107 bltD 2.3.1.57 - K ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 FR47-like protein
PFOHNOAK_03376 2.47e-155 ydhB - - S ko:K07090 - ko00000 membrane transporter protein
PFOHNOAK_03377 6.16e-198 - - - K - - - Helix-turn-helix XRE-family like proteins
PFOHNOAK_03378 1.31e-286 fabF_1 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
PFOHNOAK_03379 4.55e-267 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
PFOHNOAK_03380 6.59e-249 gldA 1.1.1.6 - C ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 ko00000,ko00001,ko01000 COG0371 Glycerol dehydrogenase and related enzymes
PFOHNOAK_03381 6.07e-192 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
PFOHNOAK_03382 5.28e-127 ynaD - - J - - - Acetyltransferase (GNAT) domain
PFOHNOAK_03383 0.0 expZ - - S ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ABC transporter
PFOHNOAK_03384 6.88e-171 puuD - - S ko:K07010 - ko00000,ko01002 Peptidase C26
PFOHNOAK_03385 0.0 ydfJ - - S ko:K06994,ko:K11625 ko02020,map02020 ko00000,ko00001 drug exporters of the RND superfamily
PFOHNOAK_03386 3.82e-140 ydfI - - K ko:K11624 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PFOHNOAK_03387 5.73e-274 ydfH 2.7.13.3 - T ko:K11623 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PFOHNOAK_03388 9.9e-49 yraG - - - ko:K06440 - ko00000 -
PFOHNOAK_03389 2.76e-83 yraF - - M - - - Spore coat protein
PFOHNOAK_03390 3.41e-279 adhB 1.1.1.1, 1.1.1.284 - E ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
PFOHNOAK_03391 4.86e-33 yraE - - - ko:K06440 - ko00000 -
PFOHNOAK_03392 3.45e-64 yraD - - M ko:K06439 - ko00000 Spore coat protein
PFOHNOAK_03393 4.7e-130 ydeS - - K - - - Transcriptional regulator
PFOHNOAK_03394 2.29e-245 ydeR - - EGP - - - Uncharacterised MFS-type transporter YbfB
PFOHNOAK_03396 3.45e-145 paiB - - K ko:K07734 - ko00000,ko03000 Transcriptional regulator
PFOHNOAK_03397 0.0 - - - K ko:K00375 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
PFOHNOAK_03398 4.37e-285 nhaC_1 - - C - - - antiporter
PFOHNOAK_03399 1.21e-85 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
PFOHNOAK_03400 3.03e-256 adhA - - C ko:K13979 - ko00000,ko01000 alcohol dehydrogenase
PFOHNOAK_03401 8.41e-212 - - - S - - - Sodium Bile acid symporter family
PFOHNOAK_03402 9.77e-68 ydeH - - - - - - -
PFOHNOAK_03403 1.09e-249 cfr 2.1.1.224 - J ko:K15632 - ko00000,ko01000,ko01504,ko03009 Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
PFOHNOAK_03405 5.69e-191 dapA7 4.3.3.7 - EM ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Dihydrodipicolinate synthetase family
PFOHNOAK_03406 1.3e-08 ykkA - - S - - - Protein of unknown function (DUF664)
PFOHNOAK_03409 2.66e-248 trkA - - P ko:K07222 - ko00000 Oxidoreductase
PFOHNOAK_03410 2.64e-216 czcD - - P ko:K16264 - ko00000,ko02000 COG1230 Co Zn Cd efflux system component
PFOHNOAK_03411 0.0 yvdP - - C - - - COG0277 FAD FMN-containing dehydrogenases
PFOHNOAK_03414 1.51e-36 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
PFOHNOAK_03415 9.24e-244 ydeG - - EGP - - - Major facilitator superfamily
PFOHNOAK_03416 7.12e-296 - - - K - - - COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
PFOHNOAK_03417 9.44e-220 - 3.5.1.6, 3.5.1.87 - E ko:K06016 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
PFOHNOAK_03418 5.7e-161 - - - K - - - helix_turn_helix, arabinose operon control protein
PFOHNOAK_03419 3.52e-205 - - - E - - - Peptidase dimerisation domain
PFOHNOAK_03420 3.45e-178 - - - E ko:K03837 - ko00000,ko02000 Serine transporter
PFOHNOAK_03421 4.46e-52 - - - J - - - Endoribonuclease L-PSP
PFOHNOAK_03422 6.58e-86 - - - K - - - COG1802 Transcriptional regulators
PFOHNOAK_03423 4.5e-144 dpaL 4.3.1.15 - E ko:K01751 - ko00000,ko01000 Pyridoxal-phosphate dependent enzyme
PFOHNOAK_03424 1.18e-108 - - - S - - - DinB superfamily
PFOHNOAK_03425 6.15e-233 - - - S - - - Patatin-like phospholipase
PFOHNOAK_03426 7.89e-66 - - - K - - - Transcriptional regulator PadR-like family
PFOHNOAK_03427 8.25e-131 - - - S - - - Protein of unknown function (DUF2812)
PFOHNOAK_03428 1.27e-150 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
PFOHNOAK_03429 2.42e-164 yrkJ - - S ko:K07090 - ko00000 membrane transporter protein
PFOHNOAK_03430 6.46e-49 yrkI - - O - - - Belongs to the sulfur carrier protein TusA family
PFOHNOAK_03431 3.52e-255 yrkH - - P - - - Rhodanese Homology Domain
PFOHNOAK_03432 5.17e-129 yrkF - - OP - - - Belongs to the sulfur carrier protein TusA family
PFOHNOAK_03433 7.97e-108 yrkE - - O - - - DsrE/DsrF/DrsH-like family
PFOHNOAK_03434 2.63e-53 yrkD - - S - - - protein conserved in bacteria
PFOHNOAK_03435 3.87e-42 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock
PFOHNOAK_03436 3.69e-143 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
PFOHNOAK_03437 7.58e-93 ywnA - - K - - - Transcriptional regulator
PFOHNOAK_03438 3.16e-64 ohrR - - K - - - Transcriptional regulator
PFOHNOAK_03439 3.38e-60 ohrB - - O - - - OsmC-like protein
PFOHNOAK_03440 1.5e-173 - - - I ko:K01066 - ko00000,ko01000 esterase
PFOHNOAK_03441 0.0 - - - EGP ko:K03761,ko:K03762 - ko00000,ko02000 Transporter
PFOHNOAK_03442 1.14e-190 - - - S - - - Serine aminopeptidase, S33
PFOHNOAK_03443 3.18e-123 yrkL - - S ko:K11748 - ko00000,ko02000 Flavodoxin-like fold
PFOHNOAK_03451 1.74e-75 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
PFOHNOAK_03452 1.78e-21 - - - - - - - -
PFOHNOAK_03453 0.0 tex - - K ko:K06959 - ko00000 COG2183 Transcriptional accessory protein
PFOHNOAK_03454 2.74e-139 rsbX 3.1.3.3 - KT ko:K05518 - ko00000,ko01000,ko03021 Sigma factor PP2C-like phosphatases
PFOHNOAK_03455 1.14e-180 sigB - - K ko:K03090 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PFOHNOAK_03456 5.84e-110 rsbW 2.7.11.1 - F ko:K04757 - ko00000,ko01000,ko01001,ko03021 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
PFOHNOAK_03457 9.77e-71 rsbV - - T ko:K04749 - ko00000,ko03021 Belongs to the anti-sigma-factor antagonist family
PFOHNOAK_03458 8.83e-242 rsbU 3.1.3.3 - KT ko:K07315 - ko00000,ko01000,ko03021 phosphatase
PFOHNOAK_03459 1.73e-89 rsbT 2.7.11.1 - T ko:K17752 - ko00000,ko01000,ko01001,ko03021 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
PFOHNOAK_03460 1.09e-75 rsbS - - T ko:K17762 - ko00000,ko03021 antagonist
PFOHNOAK_03461 1.05e-186 rsbR - - T ko:K17763 - ko00000,ko03021 Positive regulator of sigma-B
PFOHNOAK_03462 4.34e-75 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
PFOHNOAK_03463 6.68e-57 ndoAI - - K ko:K07723 - ko00000,ko02048,ko03000 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
PFOHNOAK_03464 5.68e-279 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PFOHNOAK_03465 6.39e-235 ydcC - - M - - - COG2834 Outer membrane lipoprotein-sorting protein
PFOHNOAK_03466 1.54e-75 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
PFOHNOAK_03467 2.08e-138 ydcA - - S - - - membrane protein (homolog of Drosophila rhomboid)
PFOHNOAK_03468 0.0 ydbT - - S ko:K08981 - ko00000 Membrane
PFOHNOAK_03469 5.73e-92 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
PFOHNOAK_03470 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
PFOHNOAK_03471 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
PFOHNOAK_03472 2.52e-257 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
PFOHNOAK_03473 2.25e-74 ydbP - - CO - - - Thioredoxin
PFOHNOAK_03474 1.15e-159 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PFOHNOAK_03475 6.58e-14 - - - S - - - Fur-regulated basic protein A
PFOHNOAK_03476 1.13e-15 - - - S - - - Fur-regulated basic protein B
PFOHNOAK_03477 3.63e-261 ydbM - - I - - - acyl-CoA dehydrogenase
PFOHNOAK_03478 1.32e-69 ydbL - - - - - - -
PFOHNOAK_03479 9.93e-167 ydbK - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
PFOHNOAK_03480 7.61e-218 ydbJ - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
PFOHNOAK_03481 1.22e-230 ydbI - - S - - - AI-2E family transporter
PFOHNOAK_03482 3.91e-287 dctA - - U ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
PFOHNOAK_03483 3.67e-153 dctR - - T ko:K02475,ko:K11692 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
PFOHNOAK_03484 0.0 dctS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
PFOHNOAK_03485 3.82e-255 dctB - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
PFOHNOAK_03486 2.24e-197 ydbD - - P ko:K07217 - ko00000 Catalase
PFOHNOAK_03487 9.36e-76 ydbC - - S - - - Domain of unknown function (DUF4937
PFOHNOAK_03488 2.65e-78 ydbB - - G - - - Cupin domain
PFOHNOAK_03489 2.34e-10 gsiB - - S ko:K06884 - ko00000 general stress protein
PFOHNOAK_03490 8.93e-181 ydbA - - P - - - EcsC protein family
PFOHNOAK_03491 1.66e-70 yvaE - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
PFOHNOAK_03492 5.53e-96 yvaD - - S - - - Family of unknown function (DUF5360)
PFOHNOAK_03493 1.95e-45 ydaT - - - - - - -
PFOHNOAK_03495 5.35e-288 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
PFOHNOAK_03496 7.18e-52 - - - - - - - -
PFOHNOAK_03497 2.27e-125 - - - - - - - -
PFOHNOAK_03498 4.69e-110 - - - - - - - -
PFOHNOAK_03500 2.99e-16 - - - - - - - -
PFOHNOAK_03502 1.42e-268 - - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Histidine kinase
PFOHNOAK_03503 2.07e-83 - - - - - - - -
PFOHNOAK_03504 6.19e-110 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
PFOHNOAK_03505 4.75e-33 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
PFOHNOAK_03506 7.02e-34 - - - - - - - -
PFOHNOAK_03507 1.03e-31 - - - - - - - -
PFOHNOAK_03508 6.22e-71 - - - S - - - Domain of unknown function (DUF4145)
PFOHNOAK_03510 3.85e-84 - - - K - - - acetyltransferase
PFOHNOAK_03511 0.0 ydaP 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
PFOHNOAK_03512 4.21e-95 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
PFOHNOAK_03513 0.0 ydaO - - E - - - amino acid
PFOHNOAK_03514 0.0 ydaN - - S - - - Bacterial cellulose synthase subunit
PFOHNOAK_03515 2.63e-302 ydaM - - M - - - Glycosyl transferase family group 2
PFOHNOAK_03516 0.0 ydaL - - S - - - Uncharacterized protein conserved in bacteria (DUF2334)
PFOHNOAK_03517 3.12e-188 ydaK - - T - - - Diguanylate cyclase, GGDEF domain
PFOHNOAK_03518 3.83e-256 ydaJ - - M - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
PFOHNOAK_03519 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PFOHNOAK_03520 3.25e-97 lrpC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
PFOHNOAK_03521 6.54e-63 ydzA - - EGP - - - Domain of unknown function (DUF3817)
PFOHNOAK_03522 7.59e-178 amj - - U - - - Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
PFOHNOAK_03523 1.83e-101 ydaG - - S - - - general stress protein
PFOHNOAK_03524 4.04e-149 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
PFOHNOAK_03525 3.91e-125 ydaE 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
PFOHNOAK_03526 3.01e-204 ydaD - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PFOHNOAK_03527 0.0 ydaB - - IQ - - - acyl-CoA ligase
PFOHNOAK_03528 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 transcriptional regulator, MtlR
PFOHNOAK_03529 6.05e-220 ycsN - - S - - - Oxidoreductase
PFOHNOAK_03530 0.0 pbpC 3.4.16.4 - M ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 Penicillin-binding Protein
PFOHNOAK_03531 5.95e-75 yczJ - - S - - - biosynthesis
PFOHNOAK_03533 1.51e-147 ycsK - - E - - - anatomical structure formation involved in morphogenesis
PFOHNOAK_03534 1.89e-166 kipR - - K - - - Transcriptional regulator
PFOHNOAK_03535 4.91e-240 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
PFOHNOAK_03536 1.05e-171 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
PFOHNOAK_03537 8.08e-191 ycsI - - S - - - Belongs to the D-glutamate cyclase family
PFOHNOAK_03538 7.29e-269 ycsG - - P - - - COG1914 Mn2 and Fe2 transporters of the NRAMP family
PFOHNOAK_03539 7.14e-180 ycsF - - S ko:K07160 - ko00000 Belongs to the UPF0271 (lamB) family
PFOHNOAK_03540 2.69e-177 ycsE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
PFOHNOAK_03542 2.89e-87 ycsD 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
PFOHNOAK_03543 2.72e-262 mtlD 1.1.1.17 - G ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 COG0246 Mannitol-1-phosphate altronate dehydrogenases
PFOHNOAK_03544 4.81e-94 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
PFOHNOAK_03545 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG2213 Phosphotransferase system, mannitol-specific IIBC component
PFOHNOAK_03546 9.6e-73 - - - - - - - -
PFOHNOAK_03547 4.98e-137 ycnK - - K ko:K21601 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
PFOHNOAK_03548 0.0 ycnJ - - P ko:K14166 - ko00000,ko02000 protein, homolog of Cu resistance protein CopC
PFOHNOAK_03549 3.4e-130 ycnI - - S - - - protein conserved in bacteria
PFOHNOAK_03550 2.4e-186 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PFOHNOAK_03551 8.27e-191 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
PFOHNOAK_03552 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
PFOHNOAK_03553 8.47e-285 gabT 2.6.1.19, 2.6.1.22 - E ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PFOHNOAK_03554 0.0 gabR - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
PFOHNOAK_03555 6.51e-69 yczG - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
PFOHNOAK_03556 1.97e-59 ycnE - - S - - - Monooxygenase
PFOHNOAK_03557 3.97e-174 - 1.5.1.39 - C ko:K10678,ko:K19286 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 ko00000,ko00001,ko01000 Nitroreductase family
PFOHNOAK_03558 1.23e-194 ycnC - - K - - - Transcriptional regulator
PFOHNOAK_03559 1.98e-313 ycnB - - EGP - - - the major facilitator superfamily
PFOHNOAK_03560 3.24e-222 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
PFOHNOAK_03561 1.61e-175 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
PFOHNOAK_03562 1.4e-212 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PFOHNOAK_03563 1.1e-210 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PFOHNOAK_03564 4.58e-316 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
PFOHNOAK_03566 6.79e-99 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
PFOHNOAK_03567 0.0 yclK - - T - - - COG0642 Signal transduction histidine kinase
PFOHNOAK_03568 3.04e-163 yclJ - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PFOHNOAK_03569 4.09e-308 yclI - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease) YclI
PFOHNOAK_03570 6.08e-154 yclH - - P ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
PFOHNOAK_03571 2.14e-313 yxeQ - - S - - - MmgE/PrpD family
PFOHNOAK_03572 4.63e-275 yxeP - - E ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
PFOHNOAK_03573 3.24e-169 yxeO - - P ko:K16960,ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
PFOHNOAK_03574 2.11e-148 yxeN - - P ko:K10009,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
PFOHNOAK_03575 7.09e-180 yxeM - - M ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
PFOHNOAK_03576 4.43e-120 yxeL - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PFOHNOAK_03577 0.0 yxeK - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PFOHNOAK_03578 6.5e-249 gerKB - - F ko:K06296 - ko00000,ko02000 Spore germination protein
PFOHNOAK_03579 2.31e-299 gerKC - - S ko:K06297 - ko00000 spore germination
PFOHNOAK_03580 0.0 gerKA - - EG ko:K06295 - ko00000 Spore germination protein
PFOHNOAK_03582 0.0 yclG - - M - - - Pectate lyase superfamily protein
PFOHNOAK_03583 0.0 dtpT - - E ko:K03305 - ko00000 amino acid peptide transporter
PFOHNOAK_03584 9.68e-100 yclD - - - - - - -
PFOHNOAK_03585 4.71e-51 - 4.1.1.61 - S ko:K21759 ko00627,ko01120,ko01220,map00627,map01120,map01220 ko00000,ko00001,ko01000 response to toxic substance
PFOHNOAK_03586 0.0 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
PFOHNOAK_03587 3.44e-130 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
PFOHNOAK_03588 5.96e-206 yclA - - K ko:K21755 - ko00000,ko03000 LysR substrate binding domain
PFOHNOAK_03589 1.14e-186 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
PFOHNOAK_03590 4.99e-154 tcyB - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
PFOHNOAK_03591 3.95e-169 tcyC - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
PFOHNOAK_03592 9.99e-141 yczE - - S ko:K07149 - ko00000 membrane
PFOHNOAK_03593 3.72e-167 sfp - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
PFOHNOAK_03594 8.58e-316 - - - E - - - Aminotransferase class I and II
PFOHNOAK_03595 6.15e-180 srfAD - - Q ko:K15657 ko02024,map02024 ko00000,ko00001,ko01008 thioesterase
PFOHNOAK_03596 0.0 srfAC - - Q ko:K15656,ko:K16121 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 COG1020 Non-ribosomal peptide synthetase modules and related proteins
PFOHNOAK_03597 0.0 srfAB - - Q ko:K15654,ko:K15655,ko:K16120 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PFOHNOAK_03598 0.0 srfAA - - Q ko:K15654,ko:K15655,ko:K16119 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PFOHNOAK_03599 1.95e-82 hxlR - - K - - - transcriptional
PFOHNOAK_03600 6.08e-137 hxlA 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 3-hexulose-6-phosphate synthase
PFOHNOAK_03601 3.11e-124 hxlB 5.3.1.27 - G ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
PFOHNOAK_03602 1.88e-101 nucA - - M - - - Deoxyribonuclease NucA/NucB
PFOHNOAK_03603 1.27e-86 nin - - S - - - Competence protein J (ComJ)
PFOHNOAK_03604 2.42e-63 - - - S - - - Protein of unknown function (DUF2680)
PFOHNOAK_03605 4.62e-95 yckC - - S - - - membrane
PFOHNOAK_03606 2.14e-282 fdh 1.1.1.1, 1.1.1.284 - E ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
PFOHNOAK_03607 7.88e-287 yciC - - S - - - GTPases (G3E family)
PFOHNOAK_03608 0.0 nasD 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PFOHNOAK_03609 3.45e-74 nasE 1.7.1.15 - P ko:K00363 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Nitrite reductase
PFOHNOAK_03610 0.0 nasF 2.1.1.107, 4.2.1.75 - H ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
PFOHNOAK_03611 2.35e-242 ycgT 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
PFOHNOAK_03612 1.67e-289 ycgP - - QT - - - COG2508 Regulator of polyketide synthase expression
PFOHNOAK_03613 6.63e-313 putP - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PFOHNOAK_03614 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
PFOHNOAK_03615 3.91e-216 ycgM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
PFOHNOAK_03616 5.05e-188 ycgL - - S ko:K07074 - ko00000 Predicted nucleotidyltransferase
PFOHNOAK_03617 9.43e-233 cah 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 Acetyl xylan esterase (AXE1)
PFOHNOAK_03618 8.64e-136 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
PFOHNOAK_03619 2.36e-288 - - - G ko:K08191,ko:K08194 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
PFOHNOAK_03620 2.22e-187 - 4.2.1.118 - G ko:K15652 ko00400,ko01110,ko01130,map00400,map01110,map01130 ko00000,ko00001,ko01000 Xylose isomerase-like TIM barrel
PFOHNOAK_03621 1.12e-139 tmrB - - S - - - AAA domain
PFOHNOAK_03622 6.96e-07 - - - S - - - Bacillus cereus group antimicrobial protein
PFOHNOAK_03623 1.29e-191 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
PFOHNOAK_03624 3.22e-146 ycgI - - S ko:K09967 - ko00000 Domain of unknown function (DUF1989)
PFOHNOAK_03625 2.31e-314 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
PFOHNOAK_03626 1.2e-191 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
PFOHNOAK_03627 2.61e-146 ycgF - - E - - - Lysine exporter protein LysE YggA
PFOHNOAK_03628 1.98e-100 ycgE - - K - - - helix_turn_helix multiple antibiotic resistance protein
PFOHNOAK_03629 0.0 mdr - - EGP - - - the major facilitator superfamily
PFOHNOAK_03630 3.66e-225 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
PFOHNOAK_03631 0.0 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
PFOHNOAK_03632 2.55e-105 ycgB - - - - - - -
PFOHNOAK_03633 1.48e-289 ycgA - - S - - - Membrane
PFOHNOAK_03634 7.29e-267 amhX - - S ko:K14665 - ko00000,ko01000,ko01002 amidohydrolase
PFOHNOAK_03635 1.16e-209 opuAC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
PFOHNOAK_03636 2.86e-184 opuAB - - P ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
PFOHNOAK_03637 7.71e-294 opuAA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
PFOHNOAK_03638 6.09e-275 yceI - - P ko:K08369 - ko00000,ko02000 Uncharacterised MFS-type transporter YbfB
PFOHNOAK_03639 1.36e-245 yceH - - P - - - Belongs to the TelA family
PFOHNOAK_03640 0.0 yceG - - S - - - Putative component of 'biosynthetic module'
PFOHNOAK_03641 2.12e-178 yceF - - P ko:K05794 - ko00000 Protein of unknown function (DUF475)
PFOHNOAK_03642 2.87e-137 yceE - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
PFOHNOAK_03643 7.32e-136 yceD - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
PFOHNOAK_03644 4.06e-140 yceC 3.5.4.33 - T ko:K11991 - ko00000,ko01000,ko03016 proteins involved in stress response, homologs of TerZ and
PFOHNOAK_03645 2.23e-233 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PFOHNOAK_03646 6.86e-174 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
PFOHNOAK_03647 1.4e-170 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
PFOHNOAK_03648 7.35e-214 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
PFOHNOAK_03649 1e-59 - - - K - - - Virulence activator alpha C-term
PFOHNOAK_03650 4.71e-62 - - - S - - - Domain of unknown function (DUF4188)
PFOHNOAK_03651 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
PFOHNOAK_03652 1.18e-176 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
PFOHNOAK_03653 2.86e-248 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
PFOHNOAK_03654 4.94e-119 - - - M ko:K17733 - ko00000,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
PFOHNOAK_03655 0.0 ycdC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
PFOHNOAK_03656 0.0 ycdB - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
PFOHNOAK_03657 2.66e-225 ycdA - - S - - - Domain of unknown function (DUF5105)
PFOHNOAK_03658 1.26e-217 yccK - - C - - - Aldo keto reductase
PFOHNOAK_03659 4.61e-250 yccF - - K ko:K07039 - ko00000 SEC-C motif
PFOHNOAK_03660 8.07e-148 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
PFOHNOAK_03661 1.04e-249 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
PFOHNOAK_03662 7.34e-129 lmrA - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
PFOHNOAK_03663 3.55e-313 lmrB - - EGP ko:K18926 - ko00000,ko00002,ko02000 the major facilitator superfamily
PFOHNOAK_03664 1.65e-264 ycbU - - E - - - Selenocysteine lyase
PFOHNOAK_03665 1.63e-152 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
PFOHNOAK_03666 6.74e-158 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PFOHNOAK_03667 8.68e-36 tatAD - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
PFOHNOAK_03668 0.0 phoD 3.1.3.1 - P ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG3540 Phosphodiesterase alkaline phosphatase D
PFOHNOAK_03669 1.75e-100 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
PFOHNOAK_03670 1.63e-82 ycbP - - S - - - Protein of unknown function (DUF2512)
PFOHNOAK_03671 1.27e-72 ydfQ - - CO - - - Thioredoxin
PFOHNOAK_03672 1.14e-83 ydfP - - S ko:K15977 - ko00000 DoxX
PFOHNOAK_03673 2.41e-232 ydfO - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
PFOHNOAK_03674 9.1e-141 ydfN - - C ko:K15976 - ko00000,ko01000 nitroreductase
PFOHNOAK_03675 1.23e-197 ydfM - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PFOHNOAK_03676 2.81e-34 rtpA - - K - - - Tryptophan RNA-binding attenuator protein inhibitory protein
PFOHNOAK_03677 1.96e-157 ycbJ - - S ko:K06979 - br01600,ko00000,ko00002,ko01504 Macrolide 2'-phosphotransferase
PFOHNOAK_03678 1.37e-219 glnL - - T ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Regulator
PFOHNOAK_03679 6.36e-272 glnJ 2.7.13.3 - T ko:K07717 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PFOHNOAK_03680 3.06e-238 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
PFOHNOAK_03681 0.0 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
PFOHNOAK_03682 1.69e-229 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine
PFOHNOAK_03683 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
PFOHNOAK_03684 5.86e-255 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
PFOHNOAK_03685 4.75e-271 gltP - - C ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
PFOHNOAK_03686 9.56e-244 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
PFOHNOAK_03687 1.5e-55 ybfN - - - - - - -
PFOHNOAK_03688 1.45e-192 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
PFOHNOAK_03689 4.26e-113 ybfM - - S - - - SNARE associated Golgi protein
PFOHNOAK_03690 3.15e-120 pssA 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PFOHNOAK_03691 6.53e-271 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
PFOHNOAK_03692 2.19e-248 ypjH - - C ko:K08317 - ko00000,ko01000 COG0371 Glycerol dehydrogenase and related enzymes
PFOHNOAK_03693 1.69e-107 - - - K - - - Helix-turn-helix XRE-family like proteins
PFOHNOAK_03694 1.05e-46 - - - - - - - -
PFOHNOAK_03695 0.0 ybfG - - M - - - Domain of unknown function (DUF1906)
PFOHNOAK_03697 2.35e-266 yoaI 1.14.14.9 - Q ko:K00483 ko00350,ko01120,ko01220,map00350,map01120,map01220 ko00000,ko00001,ko01000 COG2368 Aromatic ring hydroxylase
PFOHNOAK_03698 4.08e-23 - - - S - - - Protein of unknown function (DUF2651)
PFOHNOAK_03699 0.0 glpT - - G ko:K02445 - ko00000,ko02000 -transporter
PFOHNOAK_03700 4.93e-212 glpQ 3.1.3.1, 3.1.4.46 - C ko:K01113,ko:K01126 ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 glycerophosphoryl diester phosphodiesterase
PFOHNOAK_03701 0.0 ybeC - - E - - - amino acid
PFOHNOAK_03702 7.84e-55 ybyB - - - - - - -
PFOHNOAK_03703 5.07e-144 yqeB - - - - - - -
PFOHNOAK_03704 2.48e-52 csgA - - S - - - Sigma-G-dependent sporulation-specific SASP protein
PFOHNOAK_03705 6.33e-104 - - - S - - - Domain of unknown function (DUF4879)
PFOHNOAK_03706 1.87e-32 - - - - - - - -
PFOHNOAK_03707 1.64e-246 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
PFOHNOAK_03708 4.13e-259 - - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
PFOHNOAK_03709 4.19e-212 yfiL - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
PFOHNOAK_03710 7.12e-142 yfiK - - KT ko:K02479 - ko00000,ko02022 LuxR family transcriptional regulator
PFOHNOAK_03711 9.67e-253 - - - T - - - COG4585 Signal transduction histidine kinase
PFOHNOAK_03712 7.56e-119 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
PFOHNOAK_03713 0.0 ybxG - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
PFOHNOAK_03714 5.62e-93 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
PFOHNOAK_03715 9.9e-68 - - - S ko:K06518 - ko00000,ko02000 LrgA family
PFOHNOAK_03716 6.05e-135 yxaC - - M - - - effector of murein hydrolase
PFOHNOAK_03717 4.91e-205 dkgB - - S - - - Aldo/keto reductase family
PFOHNOAK_03718 8.23e-138 - - - S - - - ABC-2 family transporter protein
PFOHNOAK_03719 1.96e-195 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
PFOHNOAK_03720 5.36e-67 - - - - - - - -
PFOHNOAK_03722 5.44e-78 - - - S - - - Bacteriophage abortive infection AbiH
PFOHNOAK_03723 9.02e-193 - - - - - - - -
PFOHNOAK_03724 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
PFOHNOAK_03725 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PFOHNOAK_03726 1.05e-299 ybbR - - S - - - protein conserved in bacteria
PFOHNOAK_03727 9e-188 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
PFOHNOAK_03728 2.63e-150 rsiW - - K - - - Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
PFOHNOAK_03729 4.59e-127 sigW - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
PFOHNOAK_03735 3.89e-101 ybbK - - S - - - Protein of unknown function (DUF523)
PFOHNOAK_03736 1.01e-109 ybbJ - - J - - - acetyltransferase
PFOHNOAK_03737 6.37e-206 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
PFOHNOAK_03738 7.46e-313 ybbF 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
PFOHNOAK_03739 7.66e-310 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the UPF0214 family
PFOHNOAK_03740 0.0 ybbD 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
PFOHNOAK_03741 2.92e-296 ybbC - - S - - - protein conserved in bacteria
PFOHNOAK_03742 0.0 ybbB - - K ko:K21701 - ko00000,ko03000 COG2207 AraC-type DNA-binding domain-containing proteins
PFOHNOAK_03743 2.45e-219 feuA - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Iron-uptake system-binding protein
PFOHNOAK_03744 4.42e-226 feuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PFOHNOAK_03745 1.43e-229 feuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PFOHNOAK_03746 1.19e-137 ybbA - - S ko:K07017 - ko00000 Putative esterase
PFOHNOAK_03747 2.09e-220 ybaS - - S - - - Na -dependent transporter
PFOHNOAK_03748 1.11e-287 ybaR - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
PFOHNOAK_03749 6.88e-257 - 1.1.1.14, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00008 ko00040,ko00051,ko00650,ko01100,map00040,map00051,map00650,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
PFOHNOAK_03750 8.31e-226 suhB 3.1.3.25, 3.1.3.7 - G ko:K01082,ko:K01092 ko00521,ko00562,ko00920,ko01100,ko01120,ko01130,ko04070,map00521,map00562,map00920,map01100,map01120,map01130,map04070 ko00000,ko00001,ko00002,ko01000,ko03016 inositol monophosphate 1-phosphatase activity
PFOHNOAK_03751 5.18e-313 gabT 2.6.1.19 - E ko:K00823 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PFOHNOAK_03752 5.48e-280 glcP1 - - G ko:K08174 - ko00000,ko02000 Major Facilitator Superfamily
PFOHNOAK_03753 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
PFOHNOAK_03759 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
PFOHNOAK_03765 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
PFOHNOAK_03766 1.23e-180 pdaB - - G - - - Polysaccharide deacetylase
PFOHNOAK_03767 1.78e-134 kbaA - - S ko:K06349 - ko00000 Involved in the activation of the KinB signaling pathway of sporulation
PFOHNOAK_03768 3.93e-102 gerD - - - ko:K06294 - ko00000 -
PFOHNOAK_03769 2.58e-253 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
PFOHNOAK_03770 1.98e-173 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
PFOHNOAK_03771 3.1e-101 ybaK - - S - - - Protein of unknown function (DUF2521)
PFOHNOAK_03772 3.15e-108 yizA - - S - - - Damage-inducible protein DinB
PFOHNOAK_03773 5.9e-184 ybaJ - - Q - - - Methyltransferase domain
PFOHNOAK_03774 8.64e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
PFOHNOAK_03775 6.54e-102 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PFOHNOAK_03776 1.69e-179 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
PFOHNOAK_03777 2.77e-178 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PFOHNOAK_03778 4.91e-190 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PFOHNOAK_03779 3.05e-199 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PFOHNOAK_03780 4.27e-77 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
PFOHNOAK_03781 4.94e-217 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PFOHNOAK_03782 4.61e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PFOHNOAK_03783 1.54e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PFOHNOAK_03784 2.45e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
PFOHNOAK_03785 2.92e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PFOHNOAK_03786 2.71e-181 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
PFOHNOAK_03787 4.34e-158 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
PFOHNOAK_03788 3.15e-295 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
PFOHNOAK_03789 2.1e-94 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
PFOHNOAK_03790 1.59e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
PFOHNOAK_03791 4.54e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PFOHNOAK_03792 8.29e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PFOHNOAK_03793 3.14e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PFOHNOAK_03794 1.08e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PFOHNOAK_03795 1.43e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PFOHNOAK_03796 5.43e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PFOHNOAK_03797 1.43e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PFOHNOAK_03798 1.04e-78 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PFOHNOAK_03799 1.64e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PFOHNOAK_03800 1.88e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
PFOHNOAK_03801 1.38e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PFOHNOAK_03802 1.69e-151 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PFOHNOAK_03803 9.23e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PFOHNOAK_03804 2.83e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PFOHNOAK_03805 9.5e-201 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PFOHNOAK_03806 3.27e-58 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
PFOHNOAK_03807 2.59e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
PFOHNOAK_03808 1.02e-143 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PFOHNOAK_03809 2.58e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
PFOHNOAK_03810 5.06e-234 ybaC - - S - - - Alpha/beta hydrolase family
PFOHNOAK_03811 9.55e-286 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PFOHNOAK_03812 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PFOHNOAK_03813 4.85e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
PFOHNOAK_03814 9.47e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PFOHNOAK_03815 5.94e-46 rplGB - - J ko:K07590 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the eukaryotic ribosomal protein eL8 family
PFOHNOAK_03816 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PFOHNOAK_03817 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PFOHNOAK_03818 2.95e-139 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
PFOHNOAK_03819 2.84e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
PFOHNOAK_03820 8.13e-104 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PFOHNOAK_03821 8.66e-161 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
PFOHNOAK_03822 3.4e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PFOHNOAK_03823 1.28e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
PFOHNOAK_03824 3.77e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
PFOHNOAK_03825 1.39e-150 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
PFOHNOAK_03826 4.03e-115 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
PFOHNOAK_03827 2.9e-172 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PFOHNOAK_03828 4.11e-95 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
PFOHNOAK_03829 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
PFOHNOAK_03830 1.91e-152 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Serine acetyltransferase
PFOHNOAK_03831 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PFOHNOAK_03832 3.02e-111 ispF 2.7.7.60, 4.6.1.12 - I ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
PFOHNOAK_03833 1.01e-159 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
PFOHNOAK_03834 8.6e-251 yacL - - S - - - COG4956 Integral membrane protein (PIN domain superfamily)
PFOHNOAK_03835 8.93e-250 disA 2.7.7.85 - L ko:K07067 - ko00000,ko01000 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
PFOHNOAK_03836 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PFOHNOAK_03837 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
PFOHNOAK_03838 1.63e-258 mcsB 2.7.14.1 - E ko:K19405 - ko00000,ko01000 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
PFOHNOAK_03839 1.89e-82 mcsA - - S ko:K19411 - ko00000 protein with conserved CXXC pairs
PFOHNOAK_03840 2.14e-100 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
PFOHNOAK_03841 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
PFOHNOAK_03851 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
PFOHNOAK_03852 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
PFOHNOAK_03853 4.19e-239 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PFOHNOAK_03854 6.1e-40 yazB - - K - - - transcriptional
PFOHNOAK_03855 7.88e-116 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
PFOHNOAK_03856 1.13e-81 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PFOHNOAK_03857 9.13e-203 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
PFOHNOAK_03858 4.9e-207 pabC 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 4-amino-4-deoxychorismate lyase
PFOHNOAK_03859 1.79e-137 pabA 2.6.1.85 - EH ko:K01664 ko00790,map00790 ko00000,ko00001,ko01000 Anthranilate synthase
PFOHNOAK_03860 0.0 pabB 2.6.1.85 - EH ko:K01665 ko00790,map00790 ko00000,ko00001,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PFOHNOAK_03861 3.62e-216 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
PFOHNOAK_03862 1.16e-193 yacD 5.2.1.8 - O ko:K07533 - ko00000,ko01000,ko03110 peptidyl-prolyl isomerase
PFOHNOAK_03863 1.3e-205 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
PFOHNOAK_03864 9.51e-177 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
PFOHNOAK_03865 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PFOHNOAK_03866 1.05e-119 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
PFOHNOAK_03867 0.0 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
PFOHNOAK_03868 1.34e-235 yabT 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 serine threonine protein kinase
PFOHNOAK_03869 3.79e-166 yabS - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
PFOHNOAK_03870 0.0 spoIIE 3.1.3.16 - KT ko:K06382 - ko00000,ko01000 stage II sporulation protein E
PFOHNOAK_03873 3.54e-82 yabR - - J ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
PFOHNOAK_03874 1.2e-74 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
PFOHNOAK_03875 7.93e-133 yabQ - - S - - - spore cortex biosynthesis protein
PFOHNOAK_03876 5.47e-66 yabP - - S - - - Sporulation protein YabP
PFOHNOAK_03877 1.42e-48 yabO - - J - - - COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
PFOHNOAK_03878 0.0 yabN 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
PFOHNOAK_03879 0.0 yabM - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
PFOHNOAK_03880 8.02e-119 spoVT - - K ko:K04769 - ko00000,ko03000 stage V sporulation protein
PFOHNOAK_03881 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PFOHNOAK_03882 1.1e-54 yabK - - S - - - Peptide ABC transporter permease
PFOHNOAK_03883 1.01e-135 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
PFOHNOAK_03884 2.41e-134 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
PFOHNOAK_03885 2.47e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PFOHNOAK_03886 0.0 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PFOHNOAK_03887 4.23e-64 spoVG - - D ko:K06412 - ko00000 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
PFOHNOAK_03888 7.5e-83 yabJ 3.5.99.10 - J ko:K09022 - ko00000,ko01000 translation initiation inhibitor, yjgF family
PFOHNOAK_03889 5.67e-197 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
PFOHNOAK_03890 2.73e-206 ispE 2.7.1.148 - I ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
PFOHNOAK_03891 7.31e-38 sspF - - S ko:K06423 - ko00000 DNA topological change
PFOHNOAK_03892 5.32e-53 veg - - S - - - protein conserved in bacteria
PFOHNOAK_03893 1.41e-209 yabG - - S ko:K06436 - ko00000 peptidase
PFOHNOAK_03894 2.07e-203 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
PFOHNOAK_03895 7.62e-126 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
PFOHNOAK_03896 2.38e-308 yabE - - T - - - protein conserved in bacteria
PFOHNOAK_03897 2.49e-183 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD
PFOHNOAK_03898 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PFOHNOAK_03899 6.14e-58 abrB - - K ko:K06284 - ko00000,ko03000 COG2002 Regulators of stationary sporulation gene expression
PFOHNOAK_03900 9.15e-207 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PFOHNOAK_03901 6.96e-64 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
PFOHNOAK_03902 3.99e-178 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Conserved hypothetical protein 95
PFOHNOAK_03903 3.08e-56 yabA - - L - - - Involved in initiation control of chromosome replication
PFOHNOAK_03904 9e-189 yaaT - - S - - - stage 0 sporulation protein
PFOHNOAK_03905 2.82e-235 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
PFOHNOAK_03906 2.98e-94 yaaR - - S ko:K09770 - ko00000 protein conserved in bacteria
PFOHNOAK_03907 5.03e-73 yaaQ - - S - - - protein conserved in bacteria
PFOHNOAK_03908 9.05e-144 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PFOHNOAK_03909 0.0 yaaO - - E - - - Orn Lys Arg decarboxylase
PFOHNOAK_03910 4.68e-242 yaaN - - P - - - Belongs to the TelA family
PFOHNOAK_03911 1.19e-135 xpaC - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
PFOHNOAK_03912 1.82e-41 csfB - - S - - - Inhibitor of sigma-G Gin
PFOHNOAK_03915 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
PFOHNOAK_03916 6.44e-50 bofA - - S ko:K06317 - ko00000 Sigma-K factor-processing regulatory protein BofA
PFOHNOAK_03917 5.4e-43 yaaL - - S - - - Protein of unknown function (DUF2508)
PFOHNOAK_03918 6e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PFOHNOAK_03919 6.9e-52 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PFOHNOAK_03920 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PFOHNOAK_03921 1.18e-109 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
PFOHNOAK_03922 2.9e-128 yaaI - - Q - - - COG1335 Amidases related to nicotinamidase
PFOHNOAK_03923 2.9e-277 yaaH - - M ko:K06306 - ko00000 Glycoside Hydrolase Family
PFOHNOAK_03924 2.34e-148 dgk 2.7.1.113 - F ko:K15518 ko00230,map00230 ko00000,ko00001,ko01000 Deoxyguanosine kinase
PFOHNOAK_03925 4.17e-156 dck 2.7.1.74, 2.7.1.76 - F ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko01000 Deoxycytidine kinase
PFOHNOAK_03927 1.49e-254 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
PFOHNOAK_03928 1.85e-284 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PFOHNOAK_03929 1.17e-138 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
PFOHNOAK_03930 1.29e-202 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
PFOHNOAK_03931 0.0 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
PFOHNOAK_03932 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
PFOHNOAK_03933 6.49e-231 yaaC - - S - - - YaaC-like Protein
PFOHNOAK_03936 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
PFOHNOAK_03937 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PFOHNOAK_03938 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PFOHNOAK_03939 6.18e-52 yaaB - - S - - - Domain of unknown function (DUF370)
PFOHNOAK_03940 7.52e-263 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PFOHNOAK_03941 3.19e-45 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
PFOHNOAK_03942 8.12e-262 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
PFOHNOAK_03944 2.7e-40 sarR - - K - - - DNA-binding transcription factor activity
PFOHNOAK_03945 1.09e-100 - - - K - - - Transcriptional regulator
PFOHNOAK_03946 5.89e-212 pre - - D - - - plasmid recombination enzyme
PFOHNOAK_03947 1.18e-92 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase, peptidase S26
PFOHNOAK_03950 4.86e-237 - - - L - - - Replication protein
PFOHNOAK_03951 5.22e-183 - - - S - - - COG0457 FOG TPR repeat
PFOHNOAK_03954 2.7e-40 sarR - - K - - - DNA-binding transcription factor activity
PFOHNOAK_03955 1.09e-100 - - - K - - - Transcriptional regulator
PFOHNOAK_03956 5.89e-212 pre - - D - - - plasmid recombination enzyme
PFOHNOAK_03957 1.18e-92 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase, peptidase S26
PFOHNOAK_03960 4.86e-237 - - - L - - - Replication protein

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)