ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
MAPGIKHE_00001 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MAPGIKHE_00002 1.1e-259 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MAPGIKHE_00003 1.4e-40 yyzM - - S - - - Protein conserved in bacteria
MAPGIKHE_00004 1.51e-258 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MAPGIKHE_00005 4.43e-135 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MAPGIKHE_00006 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MAPGIKHE_00007 3.77e-53 yabO - - J - - - Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
MAPGIKHE_00008 1.16e-80 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
MAPGIKHE_00009 1.94e-05 - - - - - - - -
MAPGIKHE_00010 2.66e-307 - 3.5.2.6 - V ko:K01467 ko01501,ko02020,map01501,map02020 ko00000,ko00001,ko00002,ko01000 Beta-lactamase enzyme family
MAPGIKHE_00011 3.77e-307 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MAPGIKHE_00012 2.22e-126 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
MAPGIKHE_00013 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MAPGIKHE_00014 1.44e-176 - - - L ko:K07485 - ko00000 Transposase
MAPGIKHE_00015 7.39e-115 - - - L - - - Transposase
MAPGIKHE_00016 1.87e-74 - - - L ko:K07497 - ko00000 transposition
MAPGIKHE_00017 6.39e-77 - - - L ko:K07497 - ko00000 Integrase core domain protein
MAPGIKHE_00036 6.69e-27 - - - - - - - -
MAPGIKHE_00037 7.19e-83 XK27_01125 - - L ko:K07484 - ko00000 COG3436 Transposase and inactivated derivatives
MAPGIKHE_00038 1.93e-29 - - - S - - - Transposase C of IS166 homeodomain
MAPGIKHE_00039 0.0 - - - L ko:K07484 - ko00000 Transposase IS66 family
MAPGIKHE_00040 6.72e-155 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
MAPGIKHE_00041 1.34e-115 mreD - - M ko:K03571 - ko00000,ko03036 Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
MAPGIKHE_00042 0.0 - - - L ko:K07484 - ko00000 Transposase IS66 family
MAPGIKHE_00043 1.93e-29 - - - S - - - Transposase C of IS166 homeodomain
MAPGIKHE_00044 7.19e-83 XK27_01125 - - L ko:K07484 - ko00000 COG3436 Transposase and inactivated derivatives
MAPGIKHE_00045 6.69e-27 - - - - - - - -
MAPGIKHE_00046 5.49e-179 pcsB - - S ko:K21471 - ko00000,ko01000,ko01002,ko01011 CHAP domain
MAPGIKHE_00047 4.76e-224 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MAPGIKHE_00048 7.56e-36 - - - - - - - -
MAPGIKHE_00049 9.05e-280 araT - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
MAPGIKHE_00050 5.9e-185 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
MAPGIKHE_00051 3.66e-229 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MAPGIKHE_00052 1.93e-46 acpP_1 - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
MAPGIKHE_00053 1.5e-167 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
MAPGIKHE_00054 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MAPGIKHE_00055 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MAPGIKHE_00056 5.98e-242 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
MAPGIKHE_00057 6.85e-132 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MAPGIKHE_00058 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
MAPGIKHE_00059 1.7e-117 - - - L ko:K07483 - ko00000 transposase activity
MAPGIKHE_00060 2.65e-67 - - - L ko:K07497 - ko00000 transposition
MAPGIKHE_00061 4.86e-42 - - - L ko:K07497 - ko00000 Integrase core domain protein
MAPGIKHE_00062 5.12e-206 - - - S - - - CHAP domain
MAPGIKHE_00063 4.06e-306 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
MAPGIKHE_00064 2.66e-99 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MAPGIKHE_00065 1.2e-260 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MAPGIKHE_00066 3.58e-124 - 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Ketopantoate reductase
MAPGIKHE_00067 2.78e-34 - - - - - - - -
MAPGIKHE_00068 3.66e-315 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MAPGIKHE_00069 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
MAPGIKHE_00070 1.36e-90 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
MAPGIKHE_00071 5.42e-75 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
MAPGIKHE_00072 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MAPGIKHE_00073 1.85e-104 - - - S - - - Protein of unknown function (DUF3021)
MAPGIKHE_00074 4.37e-81 - - - KT - - - phosphorelay signal transduction system
MAPGIKHE_00076 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MAPGIKHE_00078 4.38e-134 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MAPGIKHE_00079 2.69e-138 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 3-methyladenine DNA glycosylase
MAPGIKHE_00080 1.39e-294 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
MAPGIKHE_00081 2.51e-261 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MAPGIKHE_00082 5.17e-86 spxA_2 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
MAPGIKHE_00096 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MAPGIKHE_00097 1.98e-298 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
MAPGIKHE_00098 4.88e-49 XK27_02060 - - S - - - Transglycosylase associated protein
MAPGIKHE_00099 1.69e-71 badR - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
MAPGIKHE_00100 1.33e-124 XK27_03570 - - S ko:K19784 - ko00000 reductase
MAPGIKHE_00101 3.01e-43 - - - L ko:K07497 - ko00000 Integrase core domain protein
MAPGIKHE_00103 7.56e-189 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
MAPGIKHE_00105 1.01e-175 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
MAPGIKHE_00106 2.46e-232 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MAPGIKHE_00107 4.15e-108 - - - S - - - Putative small multi-drug export protein
MAPGIKHE_00108 2.83e-99 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
MAPGIKHE_00109 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
MAPGIKHE_00110 1.26e-195 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
MAPGIKHE_00111 3.96e-40 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
MAPGIKHE_00112 3.22e-156 - - - L - - - Transposase
MAPGIKHE_00113 1.26e-211 - - - L ko:K07497 - ko00000 integrase core domain
MAPGIKHE_00114 6.58e-294 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
MAPGIKHE_00115 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
MAPGIKHE_00116 1.83e-183 - - - S - - - SseB protein N-terminal domain
MAPGIKHE_00117 7.75e-145 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 serine acetyltransferase
MAPGIKHE_00118 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
MAPGIKHE_00119 4.24e-90 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MAPGIKHE_00122 7.11e-172 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MAPGIKHE_00123 2.45e-111 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
MAPGIKHE_00124 3.69e-198 yitS - - S - - - DegV family
MAPGIKHE_00125 8.97e-43 - - - K - - - helix-turn-helix
MAPGIKHE_00126 1.15e-233 ykpB 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MAPGIKHE_00127 7.02e-103 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MAPGIKHE_00128 1.49e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
MAPGIKHE_00129 7.86e-285 int - - L - - - Belongs to the 'phage' integrase family
MAPGIKHE_00130 1.43e-52 - - - S - - - Helix-turn-helix domain
MAPGIKHE_00131 2.05e-214 - - - - - - - -
MAPGIKHE_00132 6.53e-118 - - - L ko:K07498 - ko00000 Transposase
MAPGIKHE_00133 1.12e-284 capA - - M ko:K07282 - ko00000 Bacterial capsule synthesis protein
MAPGIKHE_00134 1.7e-50 XK27_08630 - - T ko:K07166 - ko00000 UPF0237 protein
MAPGIKHE_00135 9.68e-309 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
MAPGIKHE_00136 6.4e-173 gpmB - - G ko:K15640 - ko00000 Phosphoglycerate mutase
MAPGIKHE_00137 2.89e-180 yodJ 3.4.16.4, 3.4.17.14 - M ko:K01286,ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
MAPGIKHE_00138 1.47e-131 acmA 3.2.1.17 - NU ko:K01185,ko:K02395 - ko00000,ko01000,ko02035 amidase activity
MAPGIKHE_00139 3.96e-253 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MAPGIKHE_00140 8.45e-107 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MAPGIKHE_00141 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
MAPGIKHE_00142 4.85e-258 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MAPGIKHE_00143 2.49e-177 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MAPGIKHE_00144 7.41e-177 thiD 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 phosphomethylpyrimidine kinase
MAPGIKHE_00145 5.76e-80 hmpT - - S - - - membrane
MAPGIKHE_00159 1.2e-50 amd - - E - - - Peptidase dimerisation domain
MAPGIKHE_00160 1.43e-296 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
MAPGIKHE_00161 1.94e-110 - - - - - - - -
MAPGIKHE_00162 7.24e-102 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 DNA-templated transcription, initiation
MAPGIKHE_00163 9.72e-191 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
MAPGIKHE_00164 7.54e-285 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MAPGIKHE_00165 3.71e-119 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MAPGIKHE_00166 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MAPGIKHE_00167 1.45e-108 XK27_03960 - - S - - - Protein of unknown function (DUF3013)
MAPGIKHE_00168 1.08e-106 - 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
MAPGIKHE_00169 4.09e-222 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
MAPGIKHE_00170 6.09e-173 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MAPGIKHE_00171 7.94e-75 - 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 nucleotide catabolic process
MAPGIKHE_00172 1.04e-176 cpdB 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
MAPGIKHE_00173 5.62e-233 cpdB 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
MAPGIKHE_00174 1.45e-124 nrdI - - F ko:K03647 - ko00000 Belongs to the NrdI family
MAPGIKHE_00175 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MAPGIKHE_00176 7.03e-98 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MAPGIKHE_00177 3.09e-13 dex 3.2.1.11 GH66 G ko:K05988 ko00500,map00500 ko00000,ko00001,ko01000 Glycosyl hydrolase family 66
MAPGIKHE_00178 6.67e-33 dex 3.2.1.11 GH66 G ko:K05988 ko00500,map00500 ko00000,ko00001,ko01000 Glycosyl hydrolase family 66
MAPGIKHE_00179 9.76e-23 dex 3.2.1.11 GH66 G ko:K05988 ko00500,map00500 ko00000,ko00001,ko01000 Glycosyl hydrolase family 66
MAPGIKHE_00180 3.28e-54 dex 3.2.1.11 GH66 G ko:K05988 ko00500,map00500 ko00000,ko00001,ko01000 Glycosyl hydrolase family 66
MAPGIKHE_00181 9.52e-303 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MAPGIKHE_00182 1.71e-144 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MAPGIKHE_00183 2.7e-145 - - - K - - - Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
MAPGIKHE_00184 2.48e-256 XK27_00055 - - P - - - Major Facilitator
MAPGIKHE_00185 1.74e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MAPGIKHE_00186 8.47e-126 - - - V - - - VanZ like family
MAPGIKHE_00187 6.78e-09 - - - D - - - nuclear chromosome segregation
MAPGIKHE_00189 3e-168 glnQ - - E ko:K17076 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
MAPGIKHE_00190 0.0 XK27_05795 - - P ko:K17073,ko:K17074 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MAPGIKHE_00191 1.01e-195 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MAPGIKHE_00192 8.3e-172 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
MAPGIKHE_00193 6.92e-246 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 transferase
MAPGIKHE_00194 1.82e-184 sufC - - O ko:K09013 - ko00000,ko02000 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
MAPGIKHE_00195 3.33e-298 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
MAPGIKHE_00196 4.01e-301 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MAPGIKHE_00197 7.13e-98 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
MAPGIKHE_00198 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
MAPGIKHE_00199 4.23e-23 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
MAPGIKHE_00200 1.64e-179 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
MAPGIKHE_00201 1.6e-36 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MAPGIKHE_00202 4.35e-112 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MAPGIKHE_00203 3.48e-12 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MAPGIKHE_00204 3.42e-50 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MAPGIKHE_00205 9.63e-38 oppD - - P ko:K02031,ko:K02032,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MAPGIKHE_00206 1.15e-43 oppD - - P ko:K02031,ko:K02032,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MAPGIKHE_00207 9.75e-90 - - - P ko:K02031,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MAPGIKHE_00208 4.16e-58 oppD - - P ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MAPGIKHE_00209 3.88e-213 oppF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MAPGIKHE_00210 2.04e-05 - - - - - - - -
MAPGIKHE_00211 3.89e-14 - - - - - - - -
MAPGIKHE_00212 9.47e-202 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MAPGIKHE_00213 2.41e-234 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MAPGIKHE_00214 1.06e-163 - - - K ko:K20374,ko:K21405 ko02024,map02024 ko00000,ko00001,ko03000 sequence-specific DNA binding
MAPGIKHE_00215 0.0 - - - KLT - - - serine threonine protein kinase
MAPGIKHE_00216 1.03e-284 - - - EGP - - - Major facilitator Superfamily
MAPGIKHE_00217 1.28e-94 adcR - - K - - - transcriptional
MAPGIKHE_00218 5.07e-175 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MAPGIKHE_00219 5.29e-167 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
MAPGIKHE_00220 1.45e-208 mleP2 - - S ko:K07088 - ko00000 Transporter, auxin efflux carrier (AEC) family protein
MAPGIKHE_00221 1.83e-88 ptsG 2.7.1.208 - G ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
MAPGIKHE_00222 0.0 ptsG 2.7.1.208 - G ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
MAPGIKHE_00223 7.18e-187 rgfB 3.1.3.90 - L ko:K06896 ko00500,map00500 ko00000,ko00001,ko01000 endonuclease exonuclease phosphatase family protein
MAPGIKHE_00224 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
MAPGIKHE_00225 3.92e-163 yeeN - - K - - - transcriptional regulatory protein
MAPGIKHE_00226 9.27e-66 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 protein transport
MAPGIKHE_00227 1.76e-182 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MAPGIKHE_00228 1.29e-187 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
MAPGIKHE_00229 7.72e-295 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
MAPGIKHE_00230 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MAPGIKHE_00231 0.0 XK27_00665 - - S ko:K01989,ko:K05832 - ko00000,ko00002,ko02000 ABC transporter substrate binding protein
MAPGIKHE_00232 8.63e-183 cmpC - - S ko:K05833 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
MAPGIKHE_00233 1.23e-54 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MAPGIKHE_00234 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MAPGIKHE_00235 1.7e-117 - - - L ko:K07483 - ko00000 transposase activity
MAPGIKHE_00236 2.65e-67 - - - L ko:K07497 - ko00000 transposition
MAPGIKHE_00237 6.19e-40 - - - L ko:K07497 - ko00000 Integrase core domain protein
MAPGIKHE_00240 3.02e-23 - - - - - - - -
MAPGIKHE_00241 1.55e-72 WQ51_06355 - - S - - - TM2 domain
MAPGIKHE_00242 1.94e-211 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
MAPGIKHE_00243 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
MAPGIKHE_00244 4.01e-30 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
MAPGIKHE_00245 3.64e-34 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Belongs to the SecE SEC61-gamma family
MAPGIKHE_00246 2.8e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
MAPGIKHE_00247 1.17e-110 - 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 - I ko:K01096,ko:K19302 ko00550,ko00564,ko01100,map00550,map00564,map01100 ko00000,ko00001,ko01000,ko01011 phosphatidate phosphatase activity
MAPGIKHE_00248 8.94e-63 cof - - Q - - - phosphatase activity
MAPGIKHE_00249 2.69e-47 cof - - Q - - - phosphatase activity
MAPGIKHE_00250 1.04e-126 - - - K ko:K22103 - ko00000,ko03000 transcriptional regulator (DeoR family)
MAPGIKHE_00251 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
MAPGIKHE_00252 7.76e-30 - - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
MAPGIKHE_00253 3.44e-83 - - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
MAPGIKHE_00254 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MAPGIKHE_00255 6.15e-195 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MAPGIKHE_00256 1.37e-99 yhaI - - L - - - Membrane
MAPGIKHE_00257 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
MAPGIKHE_00258 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
MAPGIKHE_00259 1.72e-141 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MAPGIKHE_00260 7.25e-123 ypsA - - S - - - Belongs to the UPF0398 family
MAPGIKHE_00261 1.97e-66 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MAPGIKHE_00262 7.19e-282 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
MAPGIKHE_00263 0.0 mapZ - - D ko:K20073 - ko00000 Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
MAPGIKHE_00264 0.0 snf - - L - - - Superfamily II DNA RNA helicases, SNF2 family'
MAPGIKHE_00265 2.2e-35 snf - - L - - - Superfamily II DNA RNA helicases, SNF2 family'
MAPGIKHE_00266 5.18e-27 XK27_11680 - - - - - - -
MAPGIKHE_00267 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
MAPGIKHE_00268 3.16e-107 XK27_09675 - - K ko:K07105 - ko00000 -acetyltransferase
MAPGIKHE_00269 0.0 mltG - - ADL ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MAPGIKHE_00270 1.17e-100 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MAPGIKHE_00271 1.08e-106 - - - L ko:K07497 - ko00000 Integrase core domain protein
MAPGIKHE_00272 3.59e-210 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MAPGIKHE_00273 3.88e-60 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
MAPGIKHE_00274 6.83e-169 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MAPGIKHE_00275 8.25e-121 XK27_09705 - - S ko:K06950 - ko00000 HD superfamily hydrolase
MAPGIKHE_00276 9.91e-145 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
MAPGIKHE_00278 1.42e-310 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MAPGIKHE_00279 2.12e-119 - - - K - - - transcriptional regulator
MAPGIKHE_00280 5.74e-48 - - - S ko:K09976 - ko00000 UPF0154 protein
MAPGIKHE_00281 1.89e-188 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
MAPGIKHE_00282 1.64e-236 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MAPGIKHE_00283 7.82e-128 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
MAPGIKHE_00284 1.49e-112 ykuL - - S - - - CBS domain
MAPGIKHE_00285 1.02e-175 xerD - - L - - - tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
MAPGIKHE_00286 1.94e-155 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MAPGIKHE_00287 7.56e-129 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MAPGIKHE_00288 3.14e-179 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
MAPGIKHE_00289 1.05e-53 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
MAPGIKHE_00290 0.0 trkH - - P ko:K03498 - ko00000,ko02000 Cation transport protein
MAPGIKHE_00291 1.1e-311 trkA - - P ko:K03499 - ko00000,ko02000 Potassium transporter peripheral membrane component
MAPGIKHE_00292 1.34e-125 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MAPGIKHE_00293 3.96e-117 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MAPGIKHE_00294 1.23e-143 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Membrane-associated phospholipid phosphatase
MAPGIKHE_00295 2.94e-206 - - - K ko:K20342,ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 sequence-specific DNA binding
MAPGIKHE_00296 1.13e-44 - - - V ko:K06147,ko:K06148,ko:K20344 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko02000 protein secretion by the type I secretion system
MAPGIKHE_00297 2.45e-141 comA - - V ko:K06147,ko:K06148,ko:K20344 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
MAPGIKHE_00298 3.37e-68 comA - - V ko:K06147,ko:K06148,ko:K20344 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
MAPGIKHE_00299 4.55e-286 B4168_4126 - - L ko:K07493 - ko00000 Transposase
MAPGIKHE_00300 2.9e-107 comA - - V ko:K06147,ko:K06148,ko:K20344 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
MAPGIKHE_00301 3.67e-62 yhaI - - L - - - Membrane
MAPGIKHE_00302 8.86e-69 - - - S - - - Domain of unknown function (DUF4173)
MAPGIKHE_00303 6.21e-124 ureI - - S ko:K03191 ko05120,map05120 ko00000,ko00001,ko02000 AmiS/UreI family transporter
MAPGIKHE_00304 1.02e-61 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
MAPGIKHE_00305 3.78e-72 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
MAPGIKHE_00306 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
MAPGIKHE_00307 2.74e-101 ureE - - O ko:K03187 - ko00000 enzyme active site formation
MAPGIKHE_00308 5.24e-169 ureF - - O ko:K03188 - ko00000 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
MAPGIKHE_00309 4.71e-142 ureG - - KO ko:K03189 - ko00000 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
MAPGIKHE_00310 6.97e-204 ureD - - O ko:K03190 - ko00000 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
MAPGIKHE_00311 2.77e-224 cbiM - - P ko:K02007 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PDGLE domain
MAPGIKHE_00312 3.37e-176 nikQ - - P ko:K02008 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport protein
MAPGIKHE_00313 3.03e-168 - - - P ko:K02006 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MAPGIKHE_00314 8.93e-188 - - - ET ko:K02030 - ko00000,ko00002,ko02000 amino acid transport
MAPGIKHE_00315 9.14e-302 - - - L ko:K07485 - ko00000 Transposase
MAPGIKHE_00316 1.16e-208 metQ - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
MAPGIKHE_00317 3.18e-204 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
MAPGIKHE_00318 1.09e-79 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase activity
MAPGIKHE_00319 2.53e-242 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MAPGIKHE_00320 7.21e-143 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
MAPGIKHE_00321 1.03e-267 sstT - - E ko:K07862 - ko00000,ko02000 Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
MAPGIKHE_00322 7.59e-204 ilvH - - S - - - S-adenosyl-l-methionine hydroxide adenosyltransferase
MAPGIKHE_00323 8.01e-125 - - - S ko:K16924 - ko00000,ko00002,ko02000 UPF0397 protein
MAPGIKHE_00324 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
MAPGIKHE_00325 5.03e-191 cbiQ - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
MAPGIKHE_00326 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MAPGIKHE_00327 2.52e-16 ulaG - - S ko:K03476 ko00053,ko01100,ko01120,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 L-ascorbate 6-phosphate lactonase
MAPGIKHE_00328 1.98e-157 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
MAPGIKHE_00329 4.26e-307 ktrB - - P ko:K03498 - ko00000,ko02000 COG0168 Trk-type K transport systems, membrane components
MAPGIKHE_00330 1.5e-168 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Ribosomal RNA small subunit methyltransferase G
MAPGIKHE_00331 6.87e-120 ylbN - - K ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
MAPGIKHE_00332 2.69e-158 csrR - - T - - - Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MAPGIKHE_00333 0.0 covS - - T - - - Histidine kinase
MAPGIKHE_00334 1.46e-106 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MAPGIKHE_00335 1.28e-276 dnaB - - L ko:K03346 - ko00000,ko03032 Replication initiation and membrane attachment
MAPGIKHE_00336 1.53e-213 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
MAPGIKHE_00337 4.84e-313 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
MAPGIKHE_00338 1.97e-116 yrdC - - Q - - - isochorismatase
MAPGIKHE_00339 7.76e-135 B4168_4126 - - L ko:K07493 - ko00000 Transposase
MAPGIKHE_00340 2.31e-306 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MAPGIKHE_00341 1.52e-81 manO - - S - - - protein conserved in bacteria
MAPGIKHE_00342 8.56e-217 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose fructose sorbose family IID component
MAPGIKHE_00343 3.59e-163 manM - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 pts system
MAPGIKHE_00344 1.39e-231 manL 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
MAPGIKHE_00345 1.84e-181 XK27_00940 3.5.1.9 - S ko:K07130 ko00380,ko00630,ko01100,map00380,map00630,map01100 ko00000,ko00001,ko00002,ko01000 Metal-dependent hydrolase
MAPGIKHE_00346 1.46e-196 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
MAPGIKHE_00347 3.87e-315 XK27_07275 - - S ko:K06901 - ko00000,ko02000 permease
MAPGIKHE_00348 1.54e-101 ydiB - - M ko:K06925 - ko00000,ko03016 ATPase or kinase
MAPGIKHE_00349 1.91e-119 - - - M - - - Acetyltransferase GNAT Family
MAPGIKHE_00350 1.76e-278 brpA - - K - - - Transcriptional
MAPGIKHE_00351 3.06e-105 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
MAPGIKHE_00352 2.28e-270 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
MAPGIKHE_00353 6.68e-64 ylxR - - K ko:K07742 - ko00000 Nucleic-acid-binding protein implicated in transcription termination
MAPGIKHE_00354 2.19e-56 ylxQ - - J - - - ribosomal protein
MAPGIKHE_00355 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MAPGIKHE_00356 9.81e-77 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MAPGIKHE_00357 1.95e-13 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 cytokinin biosynthetic process
MAPGIKHE_00358 1.52e-28 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 cytokinin biosynthetic process
MAPGIKHE_00359 3.22e-33 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 cytokinin biosynthetic process
MAPGIKHE_00360 3.86e-299 femA 2.3.2.17 - V ko:K11694 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01011 protein involved in methicillin resistance
MAPGIKHE_00361 0.0 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MAPGIKHE_00362 0.0 ytgP - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
MAPGIKHE_00363 3.07e-114 pacL - - P - - - cation transport ATPase
MAPGIKHE_00364 1.76e-258 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
MAPGIKHE_00365 3.13e-283 malY 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
MAPGIKHE_00366 9.67e-12 sacB 2.4.1.10, 2.4.1.9 GH68 G ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 Belongs to the glycosyl hydrolase 68 family
MAPGIKHE_00367 1.06e-145 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MAPGIKHE_00368 2.64e-135 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MAPGIKHE_00369 2.34e-97 ylbF - - S - - - Belongs to the UPF0342 family
MAPGIKHE_00370 1.77e-61 ylbG - - S - - - UPF0298 protein
MAPGIKHE_00371 3.94e-271 livJ - - E ko:K01999 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
MAPGIKHE_00372 8.19e-190 livH - - E ko:K01997 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
MAPGIKHE_00373 7.76e-183 livM - - E ko:K01998 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
MAPGIKHE_00374 6.57e-176 livG - - E ko:K01995 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
MAPGIKHE_00375 1.32e-157 livF - - E ko:K01996 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
MAPGIKHE_00376 6.12e-90 acuB - - S ko:K04767 - ko00000 IMP dehydrogenase activity
MAPGIKHE_00377 3.6e-56 acuB - - S ko:K04767 - ko00000 IMP dehydrogenase activity
MAPGIKHE_00378 1.3e-214 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
MAPGIKHE_00379 3.86e-143 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
MAPGIKHE_00380 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
MAPGIKHE_00381 1.02e-158 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
MAPGIKHE_00382 4.11e-123 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MAPGIKHE_00390 9.95e-215 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
MAPGIKHE_00391 9.03e-141 - - - S - - - Domain of unknown function (DUF1803)
MAPGIKHE_00392 9.83e-133 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
MAPGIKHE_00393 3.96e-179 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
MAPGIKHE_00394 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MAPGIKHE_00395 7.59e-245 asnA 6.3.1.1 - E ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
MAPGIKHE_00396 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
MAPGIKHE_00397 8.42e-149 - - - S - - - Haloacid dehalogenase-like hydrolase
MAPGIKHE_00398 4.99e-180 phaB 5.3.3.14, 5.3.3.18 - I ko:K15866,ko:K18474 ko00061,ko00360,ko01120,map00061,map00360,map01120 ko00000,ko00001,ko01000,ko01004 Belongs to the enoyl-CoA hydratase isomerase family
MAPGIKHE_00399 4.43e-95 XK27_02735 - - K - - - Transcriptional regulator, MarR family
MAPGIKHE_00400 1.88e-224 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MAPGIKHE_00401 2.12e-40 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
MAPGIKHE_00402 4.59e-221 fabK 1.3.1.9 - S ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 2-Nitropropane dioxygenase
MAPGIKHE_00403 3.32e-211 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
MAPGIKHE_00404 8.26e-165 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
MAPGIKHE_00405 1.83e-297 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MAPGIKHE_00406 2.48e-87 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MAPGIKHE_00407 1.19e-93 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MAPGIKHE_00408 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
MAPGIKHE_00409 1.2e-204 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MAPGIKHE_00410 9.33e-177 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
MAPGIKHE_00411 6.58e-116 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MAPGIKHE_00412 1.45e-83 - - - L ko:K07498 - ko00000 Transposase
MAPGIKHE_00413 1.04e-309 rny - - D ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
MAPGIKHE_00414 2.06e-93 - - - L ko:K07485 - ko00000 Transposase
MAPGIKHE_00415 4.57e-164 fruR - - K ko:K03436 - ko00000,ko03000 transcriptional
MAPGIKHE_00416 7.54e-211 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
MAPGIKHE_00417 1.35e-25 - 2.7.1.202 - GT ko:K02768,ko:K02769 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
MAPGIKHE_00418 1.15e-70 fruA 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MAPGIKHE_00419 2.08e-205 fruA 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MAPGIKHE_00420 1.06e-56 fruA 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MAPGIKHE_00421 0.0 gor 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MAPGIKHE_00422 0.0 - - - L ko:K07484 - ko00000 Transposase IS66 family
MAPGIKHE_00423 1.93e-29 - - - S - - - Transposase C of IS166 homeodomain
MAPGIKHE_00424 7.19e-83 XK27_01125 - - L ko:K07484 - ko00000 COG3436 Transposase and inactivated derivatives
MAPGIKHE_00425 6.69e-27 - - - - - - - -
MAPGIKHE_00426 1.08e-309 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
MAPGIKHE_00428 1.8e-271 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
MAPGIKHE_00429 5.18e-291 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MAPGIKHE_00430 0.0 gtf1 - - M - - - An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
MAPGIKHE_00431 0.0 gtf2 - - M - - - A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
MAPGIKHE_00432 1.6e-38 - 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 acetyltransferase
MAPGIKHE_00433 1.13e-37 - 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 acetyltransferase
MAPGIKHE_00434 1.99e-64 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
MAPGIKHE_00435 1.55e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
MAPGIKHE_00436 1.28e-157 ydaF_2 - - J - - - COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MAPGIKHE_00437 1.11e-78 WQ51_03320 - - S - - - cog cog4835
MAPGIKHE_00438 2.56e-76 - - - S - - - EDD domain protein, DegV family
MAPGIKHE_00439 2.77e-95 - - - S - - - EDD domain protein, DegV family
MAPGIKHE_00440 6.34e-179 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MAPGIKHE_00441 5.33e-286 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MAPGIKHE_00442 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 abc transporter atp-binding protein
MAPGIKHE_00443 6.69e-27 - - - - - - - -
MAPGIKHE_00444 7.19e-83 XK27_01125 - - L ko:K07484 - ko00000 COG3436 Transposase and inactivated derivatives
MAPGIKHE_00445 1.93e-29 - - - S - - - Transposase C of IS166 homeodomain
MAPGIKHE_00446 0.0 - - - L ko:K07484 - ko00000 Transposase IS66 family
MAPGIKHE_00447 1.12e-27 - - - S - - - Short repeat of unknown function (DUF308)
MAPGIKHE_00448 1.68e-176 - - - F - - - AdP-ribose pyrophosphatase
MAPGIKHE_00449 1.01e-275 nadR - - H - - - adenylyltransferase
MAPGIKHE_00450 0.0 gdhA 1.4.1.4 - E ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
MAPGIKHE_00451 2.73e-92 def_1 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
MAPGIKHE_00453 4.4e-101 - - - K - - - DNA-binding transcription factor activity
MAPGIKHE_00454 0.0 lmrA1 - - V ko:K02021,ko:K06147 - ko00000,ko02000 abc transporter atp-binding protein
MAPGIKHE_00455 0.0 lmrA2 - - V ko:K06147 - ko00000,ko02000 abc transporter atp-binding protein
MAPGIKHE_00456 6.54e-58 - - - K - - - Acetyltransferase (GNAT) family
MAPGIKHE_00457 8.72e-99 sptS - - T - - - Histidine kinase
MAPGIKHE_00458 1.38e-168 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
MAPGIKHE_00459 9.6e-119 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MAPGIKHE_00460 1.67e-206 yitL - - S ko:K00243 - ko00000 Protein conserved in bacteria
MAPGIKHE_00461 3.3e-47 yozE - - S - - - Belongs to the UPF0346 family
MAPGIKHE_00462 6.29e-180 sip - - M - - - LysM domain protein
MAPGIKHE_00463 6.47e-244 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
MAPGIKHE_00467 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MAPGIKHE_00468 1.26e-211 - - - K - - - transcriptional regulator (lysR family)
MAPGIKHE_00469 3.31e-238 coiA - - S ko:K06198 - ko00000 Competence protein
MAPGIKHE_00470 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
MAPGIKHE_00471 2.39e-164 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-Methyltransferase
MAPGIKHE_00472 9.95e-225 prsA 3.1.3.16, 5.2.1.8 - O ko:K01802,ko:K03769,ko:K07533,ko:K20074 - ko00000,ko01000,ko01009,ko03110 peptidyl-prolyl cis-trans isomerase activity
MAPGIKHE_00473 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MAPGIKHE_00474 9.01e-121 - - - M - - - GBS Bsp-like repeat
MAPGIKHE_00475 4.48e-62 - - - M - - - GBS Bsp-like repeat
MAPGIKHE_00476 8.72e-90 - 3.4.17.14, 3.5.1.28 - NU ko:K01448,ko:K02395,ko:K07260 ko00550,ko01100,ko01502,ko01503,ko02020,map00550,map01100,map01502,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko02035,ko03036 amidase activity
MAPGIKHE_00477 3.78e-38 - 3.4.17.14, 3.5.1.28 - NU ko:K01448,ko:K02395,ko:K07260 ko00550,ko01100,ko01502,ko01503,ko02020,map00550,map01100,map01502,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko02035,ko03036 amidase activity
MAPGIKHE_00478 1.29e-186 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MAPGIKHE_00479 2.02e-290 mtnE - - E ko:K08969 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 mutations do not affect methionine salvage in vivo however
MAPGIKHE_00480 1.07e-240 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MAPGIKHE_00481 1.41e-283 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MAPGIKHE_00482 2.98e-163 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
MAPGIKHE_00483 2.64e-266 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
MAPGIKHE_00484 1.7e-32 icaB - - G - - - deacetylase
MAPGIKHE_00485 1.3e-285 B4168_4126 - - L ko:K07493 - ko00000 Transposase
MAPGIKHE_00486 3.75e-18 - - - M - - - Acetyltransferase GNAT Family
MAPGIKHE_00487 9.25e-158 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MAPGIKHE_00488 1.25e-174 - - - HJ - - - the current gene model (or a revised gene model) may contain a frame shift
MAPGIKHE_00489 5.09e-09 B4168_4126 - - L ko:K07493 - ko00000 Transposase
MAPGIKHE_00490 1.14e-139 icaB - - G - - - deacetylase
MAPGIKHE_00491 8.5e-303 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
MAPGIKHE_00492 1.5e-197 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MAPGIKHE_00493 1.04e-192 rarD - - S ko:K05786 - ko00000,ko02000 Transporter
MAPGIKHE_00495 3.61e-17 coiA - - S ko:K06198 - ko00000 Competence protein
MAPGIKHE_00496 1.48e-136 - - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MAPGIKHE_00497 7.34e-63 - 2.3.1.128, 5.2.1.8 - J ko:K03768,ko:K03790 - ko00000,ko01000,ko03009,ko03110 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MAPGIKHE_00498 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MAPGIKHE_00499 5.88e-23 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MAPGIKHE_00500 4.44e-160 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
MAPGIKHE_00501 1.78e-102 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 ATP synthase F(0) sector subunit b
MAPGIKHE_00502 6.07e-114 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MAPGIKHE_00503 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MAPGIKHE_00504 9.48e-204 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MAPGIKHE_00505 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MAPGIKHE_00506 1.72e-94 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
MAPGIKHE_00507 2.88e-292 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
MAPGIKHE_00508 7.86e-286 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MAPGIKHE_00509 6.58e-175 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MAPGIKHE_00510 5.91e-143 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MAPGIKHE_00511 6.71e-208 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 dna polymerase iii
MAPGIKHE_00512 3.48e-178 yaaT - - S - - - stage 0 sporulation protein
MAPGIKHE_00513 2.84e-73 yabA - - L - - - Involved in initiation control of chromosome replication
MAPGIKHE_00514 7.25e-206 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MAPGIKHE_00515 6.27e-298 amt - - P ko:K03320 - ko00000,ko02000 Ammonium Transporter
MAPGIKHE_00516 3.27e-71 glnB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
MAPGIKHE_00517 2.28e-140 mur1 - CBM50 NU ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 mannosyl-glycoprotein
MAPGIKHE_00518 9.79e-192 XK27_04800 - - S - - - Sucrose-6F-phosphate phosphohydrolase
MAPGIKHE_00519 4.96e-116 yjbB - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
MAPGIKHE_00520 1.7e-281 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
MAPGIKHE_00521 4.02e-69 - - - - - - - -
MAPGIKHE_00522 1.37e-34 - - - - - - - -
MAPGIKHE_00523 2.45e-77 - - - - - - - -
MAPGIKHE_00524 2.48e-226 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
MAPGIKHE_00525 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
MAPGIKHE_00526 1.42e-52 ynzC - - S - - - UPF0291 protein
MAPGIKHE_00527 0.0 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 permease
MAPGIKHE_00529 3.37e-28 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
MAPGIKHE_00530 1.43e-91 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
MAPGIKHE_00531 5.74e-153 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
MAPGIKHE_00532 6.53e-94 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
MAPGIKHE_00533 6.12e-180 ppiA 5.2.1.8 - O ko:K01802,ko:K03767,ko:K03768 ko01503,ko04217,map01503,map04217 ko00000,ko00001,ko01000,ko03110,ko04147 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MAPGIKHE_00538 1.36e-215 lysR - - K - - - transcriptional regulator (lysR family)
MAPGIKHE_00539 5.69e-100 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MAPGIKHE_00540 1.2e-208 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
MAPGIKHE_00541 6.68e-115 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MAPGIKHE_00542 8.22e-288 pyrP - - F ko:K02824 - ko00000,ko02000 uracil Permease
MAPGIKHE_00543 4.79e-221 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
MAPGIKHE_00544 9.61e-271 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 carbamoyl-phosphate synthetase glutamine chain
MAPGIKHE_00545 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 carbamoyl-phosphate synthetase ammonia chain
MAPGIKHE_00546 2.11e-171 - - - S - - - Putative SAM-dependent methyltransferase
MAPGIKHE_00547 1.92e-26 yknX - - M ko:K02005 - ko00000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MAPGIKHE_00548 4.46e-48 yknX - - M ko:K02005 - ko00000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MAPGIKHE_00549 2.28e-23 - - - V ko:K02004 - ko00000,ko00002,ko02000 permease protein
MAPGIKHE_00550 1.94e-23 - - - V ko:K02004 - ko00000,ko00002,ko02000 permease protein
MAPGIKHE_00551 6.93e-26 - - - V ko:K02004 - ko00000,ko00002,ko02000 permease protein
MAPGIKHE_00552 1.8e-11 - - - V ko:K02004 - ko00000,ko00002,ko02000 efflux transmembrane transporter activity
MAPGIKHE_00553 3.74e-34 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 efflux transmembrane transporter activity
MAPGIKHE_00554 3.14e-101 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MAPGIKHE_00555 2.46e-69 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MAPGIKHE_00557 0.0 msbA_1 - - V ko:K18887 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
MAPGIKHE_00558 0.0 lmrA - - V ko:K06147,ko:K18888 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
MAPGIKHE_00559 1.96e-251 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MAPGIKHE_00560 2.11e-157 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MAPGIKHE_00561 8.65e-293 hk02 - - T - - - signal transduction protein with a C-terminal ATPase domain
MAPGIKHE_00562 4.85e-169 rr02 - - KT - - - response regulator
MAPGIKHE_00563 1.96e-280 thiF 2.7.7.73 - H ko:K03148 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
MAPGIKHE_00564 8.21e-215 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
MAPGIKHE_00565 1.79e-157 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
MAPGIKHE_00566 3.93e-250 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
MAPGIKHE_00567 3.13e-38 XK27_00085 - - K ko:K07729 - ko00000,ko03000 Transcriptional
MAPGIKHE_00569 1.5e-182 - - - F - - - Phosphorylase superfamily
MAPGIKHE_00570 8.88e-147 - - - S - - - VIT family
MAPGIKHE_00571 5.02e-168 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
MAPGIKHE_00572 2.79e-275 hipO2 - - E ko:K01436,ko:K21613 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
MAPGIKHE_00573 1.29e-24 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 alanine dehydrogenase activity
MAPGIKHE_00574 1.36e-58 ald 1.4.1.1 - C ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
MAPGIKHE_00575 5.88e-315 merA - - C - - - Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MAPGIKHE_00576 1.33e-135 - - - J ko:K09962 - ko00000 protein conserved in bacteria
MAPGIKHE_00577 3.8e-194 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 mevalonate kinase
MAPGIKHE_00578 3.24e-222 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
MAPGIKHE_00579 6.83e-228 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 GHMP kinases N terminal domain
MAPGIKHE_00580 5.33e-243 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MAPGIKHE_00581 0.0 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MAPGIKHE_00582 2.12e-125 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 AdP-ribose pyrophosphatase
MAPGIKHE_00583 1.47e-41 - - - - - - - -
MAPGIKHE_00584 8.56e-151 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MAPGIKHE_00585 2.35e-60 - - - M ko:K02460 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02044 domain protein
MAPGIKHE_00586 1.48e-21 - - - M ko:K02460 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02044 domain protein
MAPGIKHE_00587 8.17e-242 dgs 2.4.1.208 GT4 M ko:K13677 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
MAPGIKHE_00588 0.0 pimB 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
MAPGIKHE_00589 2.58e-27 - - - - - - - -
MAPGIKHE_00590 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MAPGIKHE_00591 2.71e-60 - - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MAPGIKHE_00592 1.83e-90 - - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MAPGIKHE_00593 1.93e-210 - - - S - - - Protein of unknown function (DUF3114)
MAPGIKHE_00594 9.03e-29 - - - S - - - Protein of unknown function (DUF3114)
MAPGIKHE_00595 1.01e-151 hly-III - - K ko:K11068 - ko00000,ko02042 protein, Hemolysin III
MAPGIKHE_00596 3.81e-35 - - - K - - - hmm pf08876
MAPGIKHE_00597 1.76e-297 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
MAPGIKHE_00598 1.28e-278 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 synthase
MAPGIKHE_00599 5.15e-214 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MAPGIKHE_00600 5.77e-118 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MAPGIKHE_00601 2.97e-30 - - - - - - - -
MAPGIKHE_00602 8.89e-288 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MAPGIKHE_00603 6.75e-144 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
MAPGIKHE_00604 6.68e-80 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
MAPGIKHE_00605 2.51e-211 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
MAPGIKHE_00606 1.54e-227 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 Homocysteine
MAPGIKHE_00607 6.1e-40 - - - S - - - Domain of unknown function (DUF1912)
MAPGIKHE_00608 7.76e-21 - - - L - - - Helix-hairpin-helix DNA-binding motif class 1
MAPGIKHE_00609 1.49e-138 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MAPGIKHE_00610 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MAPGIKHE_00611 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MAPGIKHE_00612 2.38e-253 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
MAPGIKHE_00613 1.4e-21 - - - S - - - Protein of unknown function (DUF2969)
MAPGIKHE_00616 1.44e-268 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 ribosomal protein S1
MAPGIKHE_00619 5.2e-131 - - - S - - - Domain of Unknown Function with PDB structure (DUF3862)
MAPGIKHE_00620 1.97e-92 - - - M - - - Pfam SNARE associated Golgi protein
MAPGIKHE_00621 5.43e-295 murN - - V ko:K12554 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01011 FemAB family
MAPGIKHE_00622 1.27e-64 - - - S - - - oxidoreductase
MAPGIKHE_00623 3.89e-84 - - - S - - - oxidoreductase
MAPGIKHE_00624 5.47e-66 XK27_09445 - - S - - - Domain of unknown function (DUF1827)
MAPGIKHE_00625 7.82e-111 XK27_09440 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
MAPGIKHE_00626 0.0 clpE - - O ko:K03697 - ko00000,ko03110 Belongs to the ClpA ClpB family
MAPGIKHE_00627 9.09e-235 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MAPGIKHE_00628 1.15e-47 ykuJ - - S - - - protein conserved in bacteria
MAPGIKHE_00629 3.24e-151 - - - P ko:K02029 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MAPGIKHE_00630 4.45e-169 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 abc transporter atp-binding protein
MAPGIKHE_00631 3.01e-102 feoA - - P ko:K04758 - ko00000,ko02000 FeoA domain protein
MAPGIKHE_00632 0.0 feoB - - P ko:K04759 - ko00000,ko02000 transporter of a GTP-driven Fe(2 ) uptake system
MAPGIKHE_00633 9.87e-12 - - - - - - - -
MAPGIKHE_00634 1.95e-45 yugF - - I - - - carboxylic ester hydrolase activity
MAPGIKHE_00635 4.53e-30 - - - I - - - Alpha/beta hydrolase family
MAPGIKHE_00636 9.86e-202 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MAPGIKHE_00637 8.33e-191 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MAPGIKHE_00638 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 penicillin-binding protein
MAPGIKHE_00639 7.55e-136 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MAPGIKHE_00640 2.09e-83 licT - - K ko:K02538,ko:K03488 - ko00000,ko03000 transcriptional antiterminator
MAPGIKHE_00641 2.18e-112 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MAPGIKHE_00642 8.19e-84 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
MAPGIKHE_00643 1.16e-212 era - - M ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MAPGIKHE_00644 9.5e-199 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MAPGIKHE_00645 2.68e-137 coaE 2.7.1.24 - H ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MAPGIKHE_00646 1.46e-281 pmrA - - EGP ko:K08161 - ko00000,ko02000 Major Facilitator
MAPGIKHE_00647 1.06e-44 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
MAPGIKHE_00648 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MAPGIKHE_00649 5.69e-105 smpB - - O ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MAPGIKHE_00650 0.0 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MAPGIKHE_00651 1.08e-84 yugI - - J ko:K07570 - ko00000 RNA binding protein, contains ribosomal protein S1 domain
MAPGIKHE_00652 6.69e-27 - - - - - - - -
MAPGIKHE_00653 7.19e-83 XK27_01125 - - L ko:K07484 - ko00000 COG3436 Transposase and inactivated derivatives
MAPGIKHE_00654 1.93e-29 - - - S - - - Transposase C of IS166 homeodomain
MAPGIKHE_00655 1.46e-306 - - - L ko:K07484 - ko00000 Transposase IS66 family
MAPGIKHE_00656 1.41e-267 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Belongs to the peptidase M24B family
MAPGIKHE_00657 8.25e-235 ccpA - - K ko:K02529 - ko00000,ko03000 Catabolite control protein A
MAPGIKHE_00658 1.11e-34 XK27_07735 - - S - - - YjbR
MAPGIKHE_00659 1.5e-181 XK27_07735 - - S - - - YjbR
MAPGIKHE_00660 2.43e-264 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
MAPGIKHE_00661 1.64e-98 XK27_05190 - - S - - - Protein of unknown function (DUF1694)
MAPGIKHE_00662 1.75e-314 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MAPGIKHE_00664 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
MAPGIKHE_00665 8.39e-280 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
MAPGIKHE_00666 8.04e-158 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
MAPGIKHE_00667 1.72e-207 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MAPGIKHE_00668 1.39e-255 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MAPGIKHE_00669 1.29e-279 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MAPGIKHE_00670 5.52e-264 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
MAPGIKHE_00671 1.48e-71 XK26_04240 - - S - - - Belongs to the UPF0342 family
MAPGIKHE_00672 1.88e-222 hicD2 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
MAPGIKHE_00673 2.41e-297 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MAPGIKHE_00674 2.28e-113 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MAPGIKHE_00675 3.43e-197 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
MAPGIKHE_00676 0.0 msrR - - K - - - Transcriptional regulator
MAPGIKHE_00677 4.07e-199 ydiA - - P ko:K03304,ko:K11041 ko05150,map05150 ko00000,ko00001,ko02000,ko02042 C4-dicarboxylate transporter malic acid transport protein
MAPGIKHE_00678 1.56e-256 - - - I - - - acyl-CoA dehydrogenase
MAPGIKHE_00679 5.21e-126 mip - - S - - - hydroperoxide reductase activity
MAPGIKHE_00680 0.0 rumA 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MAPGIKHE_00681 9.08e-72 - - - J - - - Acetyltransferase (GNAT) domain
MAPGIKHE_00682 2.13e-31 - - - - - - - -
MAPGIKHE_00683 1.48e-29 - - - E - - - IrrE N-terminal-like domain
MAPGIKHE_00684 1.02e-73 - - - S - - - CD20-like family
MAPGIKHE_00685 8.75e-86 - - - - - - - -
MAPGIKHE_00686 7.54e-285 B4168_4126 - - L ko:K07493 - ko00000 Transposase
MAPGIKHE_00687 3.95e-92 - - - L ko:K07497 - ko00000 Integrase core domain
MAPGIKHE_00688 4.19e-92 - - - L ko:K07497 - ko00000 COG2801 Transposase and inactivated derivatives
MAPGIKHE_00690 3.12e-77 - - - S - - - Protein of unknown function (DUF1722)
MAPGIKHE_00691 4.98e-85 yqeB - - S - - - Pyrimidine dimer DNA glycosylase
MAPGIKHE_00693 3.71e-46 - - - - - - - -
MAPGIKHE_00694 7.8e-35 - - - S - - - CAAX protease self-immunity
MAPGIKHE_00695 1.31e-39 - - - S - - - CAAX protease self-immunity
MAPGIKHE_00696 7.87e-36 - - - E - - - GDSL-like Lipase/Acylhydrolase
MAPGIKHE_00697 2.55e-123 - - - - - - - -
MAPGIKHE_00698 0.0 cas9 - - L ko:K09952 - ko00000,ko01000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
MAPGIKHE_00699 9.3e-221 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MAPGIKHE_00700 8.44e-71 - - - L ko:K09951 - ko00000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MAPGIKHE_00701 7.93e-248 - - - S - - - CRISPR-associated protein Csn2 subfamily St
MAPGIKHE_00702 0.0 - - - L ko:K07484 - ko00000 Transposase IS66 family
MAPGIKHE_00703 1.93e-29 - - - S - - - Transposase C of IS166 homeodomain
MAPGIKHE_00704 7.19e-83 XK27_01125 - - L ko:K07484 - ko00000 COG3436 Transposase and inactivated derivatives
MAPGIKHE_00705 6.69e-27 - - - - - - - -
MAPGIKHE_00706 8.38e-192 XK27_03010 - - S ko:K08986 - ko00000 TIGR03943 family
MAPGIKHE_00707 1.05e-197 XK27_03015 - - S ko:K07089 - ko00000 permease
MAPGIKHE_00709 0.0 tex - - K ko:K06959 - ko00000 Transcriptional accessory protein
MAPGIKHE_00710 1.2e-54 WQ51_05770 - - KT - - - PspC domain
MAPGIKHE_00711 3.49e-219 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MAPGIKHE_00712 1.51e-190 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MAPGIKHE_00713 1.14e-26 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MAPGIKHE_00714 1.66e-91 ytxH - - S - - - General stress protein
MAPGIKHE_00716 1.23e-228 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
MAPGIKHE_00717 0.0 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
MAPGIKHE_00718 6.28e-112 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 biotin synthase
MAPGIKHE_00720 2.97e-45 XK27_12190 - - S - - - protein conserved in bacteria
MAPGIKHE_00721 4.49e-297 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
MAPGIKHE_00723 8.79e-131 - - - L ko:K07485 - ko00000 Transposase
MAPGIKHE_00724 1.57e-136 - - - E - - - LysE type translocator
MAPGIKHE_00725 1.95e-85 - - - IQ - - - PFAM AMP-dependent synthetase and ligase
MAPGIKHE_00726 5.31e-140 B4168_4126 - - L ko:K07493 - ko00000 Transposase
MAPGIKHE_00727 1.09e-133 B4168_4126 - - L ko:K07493 - ko00000 Transposase
MAPGIKHE_00728 2.44e-144 - - - L - - - Transposase
MAPGIKHE_00729 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
MAPGIKHE_00730 5.37e-20 - - - M - - - LysM domain
MAPGIKHE_00731 1.44e-75 - - - M - - - LysM domain
MAPGIKHE_00732 7.92e-29 - - - - - - - -
MAPGIKHE_00733 6.05e-220 - - - S ko:K07025 - ko00000 hydrolase
MAPGIKHE_00734 1.45e-149 pgm - - G - - - Phosphoglycerate mutase
MAPGIKHE_00735 2.49e-105 - - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MAPGIKHE_00736 1.99e-196 - 3.5.1.28 - M ko:K01447,ko:K07273 - ko00000,ko01000 Glycosyl hydrolase, family 25
MAPGIKHE_00737 1.14e-35 - - - P - - - Hemerythrin HHE cation binding domain protein
MAPGIKHE_00738 6.94e-146 - - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MAPGIKHE_00739 4.51e-14 - - - S - - - Protein of unknown function (DUF2974)
MAPGIKHE_00740 1.3e-45 - - - S - - - Protein of unknown function (DUF2974)
MAPGIKHE_00741 6.03e-22 - - - S - - - Protein of unknown function (DUF2974)
MAPGIKHE_00742 1.26e-61 sdh - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
MAPGIKHE_00743 1.79e-90 sdh - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
MAPGIKHE_00744 0.0 hsdR 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
MAPGIKHE_00745 4.1e-91 - - - S - - - Protein of unknown function (DUF1524)
MAPGIKHE_00746 2.86e-159 - - - V - - - Type I restriction modification DNA specificity domain
MAPGIKHE_00747 8.92e-57 - - - K - - - Helix-turn-helix domain
MAPGIKHE_00748 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
MAPGIKHE_00749 1.77e-60 - - - S - - - double-stranded DNA endodeoxyribonuclease activity
MAPGIKHE_00750 1.47e-116 - - - S - - - double-stranded DNA endodeoxyribonuclease activity
MAPGIKHE_00751 7.04e-223 spd - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
MAPGIKHE_00752 3.61e-119 lemA - - S ko:K03744 - ko00000 LemA family
MAPGIKHE_00753 1.63e-187 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
MAPGIKHE_00754 8.61e-97 - - - S ko:K16927 - ko00000,ko00002,ko02000 Psort location CytoplasmicMembrane, score
MAPGIKHE_00755 2.18e-73 - - - S - - - Domain of unknown function (DUF4430)
MAPGIKHE_00756 0.0 ppc 4.1.1.31 - H ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MAPGIKHE_00757 3.3e-237 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
MAPGIKHE_00758 6.73e-145 sodA 1.15.1.1 - C ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
MAPGIKHE_00759 3.03e-280 - - - V - - - D-alanyl-D-alanine carboxypeptidase
MAPGIKHE_00760 1.1e-150 pppA 3.4.23.43 - NOU ko:K02236 - ko00000,ko00002,ko01000,ko02044 Bacterial Peptidase A24 N-terminal domain
MAPGIKHE_00761 1.11e-118 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
MAPGIKHE_00762 5.6e-103 perR - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
MAPGIKHE_00763 1.58e-37 yqgQ - - S - - - protein conserved in bacteria
MAPGIKHE_00764 2.49e-230 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
MAPGIKHE_00765 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
MAPGIKHE_00766 2.68e-12 - - - S - - - Protein of unknown function (DUF3165)
MAPGIKHE_00767 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MAPGIKHE_00768 1.9e-258 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MAPGIKHE_00769 3.68e-240 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MAPGIKHE_00770 0.0 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MAPGIKHE_00771 3.08e-302 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MAPGIKHE_00772 3.98e-159 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MAPGIKHE_00773 2.09e-124 sepF - - D ko:K09772 - ko00000,ko03036 cell septum assembly
MAPGIKHE_00774 1.27e-46 yggT - - D ko:K02221 - ko00000,ko02044 integral membrane protein
MAPGIKHE_00775 1.68e-184 ylmH - - T ko:K02487,ko:K06596 ko02020,ko02025,map02020,map02025 ko00000,ko00001,ko00002,ko01001,ko02022,ko02035 S4 RNA-binding domain
MAPGIKHE_00776 5.11e-187 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division protein DivIVA
MAPGIKHE_00777 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MAPGIKHE_00778 7.94e-23 - - - - - - - -
MAPGIKHE_00779 1.18e-08 - - - - - - - -
MAPGIKHE_00780 1.43e-290 mntH_2 - - P - - - Mn2 and Fe2 transporters of the NRAMP family
MAPGIKHE_00781 1.39e-61 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 50S ribosomal protein L31
MAPGIKHE_00782 9.71e-227 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MAPGIKHE_00783 1.01e-225 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 domain protein
MAPGIKHE_00784 6.55e-196 gst - - O ko:K11209 - ko00000,ko01000 Glutathione S-transferase
MAPGIKHE_00785 1.3e-239 add 3.5.4.2, 3.5.4.4 - F ko:K01488,ko:K02029,ko:K21053 ko00230,ko01100,ko05340,map00230,map01100,map05340 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MAPGIKHE_00786 2.65e-145 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
MAPGIKHE_00787 5.57e-248 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MAPGIKHE_00788 2.61e-198 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MAPGIKHE_00789 1.46e-141 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MAPGIKHE_00790 3.56e-298 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MAPGIKHE_00791 1.82e-229 - - - S - - - 37-kD nucleoid-associated bacterial protein
MAPGIKHE_00792 3.79e-138 pvaA - - M ko:K02395 - ko00000,ko02035 lytic transglycosylase activity
MAPGIKHE_00793 0.0 yfiB1 - - V ko:K06147,ko:K06148 - ko00000,ko02000 abc transporter atp-binding protein
MAPGIKHE_00794 0.0 XK27_10035 - - V ko:K06147 - ko00000,ko02000 abc transporter atp-binding protein
MAPGIKHE_00795 4.55e-286 B4168_4126 - - L ko:K07493 - ko00000 Transposase
MAPGIKHE_00796 1.88e-14 - - - S - - - D-Ala-teichoic acid biosynthesis protein
MAPGIKHE_00797 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MAPGIKHE_00798 2.52e-302 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Membrane protein involved in D-alanine export
MAPGIKHE_00799 4.98e-48 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MAPGIKHE_00800 3.12e-311 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MAPGIKHE_00801 2.82e-44 - - - L ko:K07497 - ko00000 Integrase core domain protein
MAPGIKHE_00802 5.03e-43 - - - L ko:K07497 - ko00000 transposition
MAPGIKHE_00803 9.88e-24 - - - L ko:K07483 - ko00000 transposase activity
MAPGIKHE_00804 3.39e-50 - - - L - - - Transposase
MAPGIKHE_00805 0.0 - 3.6.3.2, 3.6.3.6, 3.6.3.8 - P ko:K01531,ko:K01535,ko:K01537 ko00190,map00190 ko00000,ko00001,ko01000 cation transport ATPase
MAPGIKHE_00806 0.0 pabB 2.6.1.85, 4.1.3.38 - EH ko:K01665,ko:K03342,ko:K13950 ko00790,map00790 ko00000,ko00001,ko01000,ko01007 component I
MAPGIKHE_00807 4.55e-286 B4168_4126 - - L ko:K07493 - ko00000 Transposase
MAPGIKHE_00809 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MAPGIKHE_00810 2.65e-212 metF 1.5.1.20 - C ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 reductase
MAPGIKHE_00811 6.69e-27 - - - - - - - -
MAPGIKHE_00812 7.19e-83 XK27_01125 - - L ko:K07484 - ko00000 COG3436 Transposase and inactivated derivatives
MAPGIKHE_00813 1.93e-29 - - - S - - - Transposase C of IS166 homeodomain
MAPGIKHE_00814 0.0 - - - L ko:K07484 - ko00000 Transposase IS66 family
MAPGIKHE_00815 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
MAPGIKHE_00816 3.72e-121 - - - S - - - ECF transporter, substrate-specific component
MAPGIKHE_00817 5.7e-124 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MAPGIKHE_00818 6.6e-158 coaB 6.3.2.5 - H ko:K21977 ko00770,map00770 ko00000,ko00001,ko00002,ko01000 Phosphopantothenate-cysteine ligase
MAPGIKHE_00819 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
MAPGIKHE_00820 5.39e-22 ciaR - - T ko:K14983 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MAPGIKHE_00821 4.29e-50 ciaH 2.7.13.3 - T ko:K14982 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MAPGIKHE_00822 2.14e-51 ciaH 2.7.13.3 - T ko:K14982 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MAPGIKHE_00823 9.25e-102 ciaH 2.7.13.3 - T ko:K14982 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MAPGIKHE_00824 1.98e-40 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 rRNA binding
MAPGIKHE_00825 1.22e-222 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
MAPGIKHE_00826 2.91e-64 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase small domain protein
MAPGIKHE_00827 6.15e-36 pdp 2.4.2.2, 2.4.2.4 - F ko:K00756,ko:K00758 ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219 ko00000,ko00001,ko01000 phosphorylase activity
MAPGIKHE_00828 5.3e-33 pdp 2.4.2.2, 2.4.2.4 - F ko:K00756,ko:K00758 ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219 ko00000,ko00001,ko01000 phosphorylase activity
MAPGIKHE_00829 1.74e-78 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
MAPGIKHE_00830 1.64e-59 pdp 2.4.2.2, 2.4.2.4 - F ko:K00756,ko:K00758 ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219 ko00000,ko00001,ko01000 phosphorylase activity
MAPGIKHE_00831 9.02e-28 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MAPGIKHE_00832 7.53e-20 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MAPGIKHE_00833 2.48e-87 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
MAPGIKHE_00834 2.73e-242 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
MAPGIKHE_00835 0.0 mglA 3.6.3.17 - S ko:K02056,ko:K06400 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MAPGIKHE_00836 9.61e-247 mglC - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
MAPGIKHE_00837 3.63e-221 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
MAPGIKHE_00838 1.3e-156 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
MAPGIKHE_00839 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
MAPGIKHE_00840 1.32e-106 ypmB - - S - - - Protein conserved in bacteria
MAPGIKHE_00841 3.85e-279 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
MAPGIKHE_00842 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
MAPGIKHE_00844 2.05e-42 - - - - - - - -
MAPGIKHE_00845 1.82e-17 - - - - - - - -
MAPGIKHE_00846 1.07e-82 aldR 3.5.99.10 - J ko:K09022 - ko00000,ko01000 endoribonuclease L-PSP
MAPGIKHE_00847 3.72e-159 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MAPGIKHE_00848 1.17e-105 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
MAPGIKHE_00849 7.17e-172 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
MAPGIKHE_00850 2.72e-122 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
MAPGIKHE_00851 1.1e-22 - - - D - - - nuclear chromosome segregation
MAPGIKHE_00852 1.48e-173 yejC - - S - - - cyclic nucleotide-binding protein
MAPGIKHE_00853 5.97e-209 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
MAPGIKHE_00854 3.04e-232 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
MAPGIKHE_00855 1.2e-207 whiA - - K ko:K09762 - ko00000 May be required for sporulation
MAPGIKHE_00856 1.29e-173 pepD - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
MAPGIKHE_00857 4.15e-52 pepD - - E ko:K08659 - ko00000,ko01000,ko01002 dipeptidase activity
MAPGIKHE_00858 2.63e-44 - - - K - - - Cold shock protein domain
MAPGIKHE_00859 3.71e-57 cspA - - K ko:K03704 - ko00000,ko03000 Cold-Shock Protein
MAPGIKHE_00860 3.06e-139 B4168_4126 - - L ko:K07493 - ko00000 Transposase
MAPGIKHE_00861 3.11e-133 B4168_4126 - - L ko:K07493 - ko00000 Transposase
MAPGIKHE_00862 0.0 copB 3.6.3.4 - P ko:K01533 - ko00000,ko01000 haloacid dehalogenase-like hydrolase
MAPGIKHE_00863 3.11e-133 B4168_4126 - - L ko:K07493 - ko00000 Transposase
MAPGIKHE_00864 5.31e-140 B4168_4126 - - L ko:K07493 - ko00000 Transposase
MAPGIKHE_00865 1.73e-106 - 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
MAPGIKHE_00866 2.72e-106 - 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
MAPGIKHE_00867 1.8e-218 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
MAPGIKHE_00868 8.39e-279 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
MAPGIKHE_00869 1.02e-107 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Bacterial transferase hexapeptide (six repeats)
MAPGIKHE_00870 5.31e-140 B4168_4126 - - L ko:K07493 - ko00000 Transposase
MAPGIKHE_00871 1.09e-133 B4168_4126 - - L ko:K07493 - ko00000 Transposase
MAPGIKHE_00872 1.45e-76 hsdS 2.1.1.72, 3.1.21.3 - V ko:K01154,ko:K07317 - ko00000,ko01000,ko02048 type I restriction modification DNA specificity domain
MAPGIKHE_00873 7.77e-144 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
MAPGIKHE_00874 1.01e-195 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
MAPGIKHE_00875 3.36e-109 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 HsdM N-terminal domain
MAPGIKHE_00876 9.44e-113 XK27_10720 - - D - - - peptidase activity
MAPGIKHE_00877 0.0 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
MAPGIKHE_00880 6.43e-219 yeiH - - S - - - Membrane
MAPGIKHE_00881 2.26e-154 - - CBM50 NU ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 muramidase
MAPGIKHE_00882 4.7e-107 - - - L ko:K07497 - ko00000 transposition
MAPGIKHE_00883 2.18e-214 cpsY - - K - - - Transcriptional regulator
MAPGIKHE_00884 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MAPGIKHE_00885 4.47e-76 phnA - - P ko:K06193 ko01120,map01120 ko00000 Alkylphosphonate utilization operon protein PhnA
MAPGIKHE_00886 3.92e-134 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter (Permease
MAPGIKHE_00887 5.28e-146 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 abc transporter atp-binding protein
MAPGIKHE_00888 1.35e-203 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
MAPGIKHE_00889 1.04e-48 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MAPGIKHE_00890 1.53e-179 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MAPGIKHE_00891 8.34e-75 adhP 1.1.1.1 - C ko:K00001,ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
MAPGIKHE_00892 2.27e-135 adhP 1.1.1.1 - C ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
MAPGIKHE_00893 1.32e-24 - 2.1.1.72 - L ko:K07316 - ko00000,ko01000,ko02048 Adenine specific DNA methylase Mod
MAPGIKHE_00894 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
MAPGIKHE_00895 3.02e-161 yvoA_2 - - K ko:K03710 - ko00000,ko03000 transcriptional
MAPGIKHE_00896 9e-72 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MAPGIKHE_00897 0.0 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MAPGIKHE_00898 8e-113 niaX - - - ko:K16788 - ko00000,ko02000 -
MAPGIKHE_00899 7.82e-118 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
MAPGIKHE_00900 1.57e-166 - - - K - - - DNA-binding helix-turn-helix protein
MAPGIKHE_00901 7.24e-204 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MAPGIKHE_00902 5.83e-175 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MAPGIKHE_00903 1.79e-215 - - - GK - - - ROK family
MAPGIKHE_00904 1.58e-200 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
MAPGIKHE_00905 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MAPGIKHE_00906 1.3e-285 B4168_4126 - - L ko:K07493 - ko00000 Transposase
MAPGIKHE_00907 1.03e-198 - - - S - - - TraX protein
MAPGIKHE_00908 2.93e-157 spaR - - KT ko:K20488 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MAPGIKHE_00909 0.0 - 2.7.13.3 - T ko:K20487 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
MAPGIKHE_00910 0.0 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MAPGIKHE_00911 2.28e-106 XK27_05470 - - E - - - Methionine synthase
MAPGIKHE_00912 7.34e-45 XK27_05470 - - E - - - Methionine synthase
MAPGIKHE_00913 1.01e-99 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
MAPGIKHE_00914 4.95e-63 pspE - - P ko:K03972 - ko00000 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MAPGIKHE_00915 3.01e-69 butA 1.1.1.304, 1.1.1.76 - IQ ko:K03366 ko00650,map00650 ko00000,ko00001,ko01000 Acetoin reductase
MAPGIKHE_00916 1.01e-24 butA 1.1.1.304, 1.1.1.76 - IQ ko:K03366 ko00650,map00650 ko00000,ko00001,ko01000 Acetoin reductase
MAPGIKHE_00917 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MAPGIKHE_00920 3.73e-54 - - - K ko:K15773 - ko00000,ko02048,ko03000 peptidyl-tyrosine sulfation
MAPGIKHE_00921 5.91e-199 - - - K - - - Transcriptional activator, Rgg GadR MutR family
MAPGIKHE_00924 3.26e-271 nirJ - - C ko:K06139,ko:K22227 - ko00000 radical SAM domain protein
MAPGIKHE_00925 3.15e-175 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
MAPGIKHE_00926 9.01e-75 - - - EGP ko:K08218 ko01501,map01501 ko00000,ko00001,ko00002,ko02000 Major facilitator Superfamily
MAPGIKHE_00927 6.69e-27 - - - - - - - -
MAPGIKHE_00928 7.19e-83 XK27_01125 - - L ko:K07484 - ko00000 COG3436 Transposase and inactivated derivatives
MAPGIKHE_00929 1.93e-29 - - - S - - - Transposase C of IS166 homeodomain
MAPGIKHE_00930 0.0 - - - L ko:K07484 - ko00000 Transposase IS66 family
MAPGIKHE_00931 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
MAPGIKHE_00932 1.34e-172 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Belongs to the alpha-acetolactate decarboxylase family
MAPGIKHE_00933 2.38e-292 - - - L ko:K07485 - ko00000 Transposase
MAPGIKHE_00934 1.95e-126 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (Permease
MAPGIKHE_00935 3.51e-146 - - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
MAPGIKHE_00936 9.28e-15 - - - - - - - -
MAPGIKHE_00937 4.42e-136 - - - K - - - Transcriptional regulator, TetR family
MAPGIKHE_00938 1.06e-203 czcD - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
MAPGIKHE_00939 2.63e-252 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
MAPGIKHE_00940 1.08e-247 adhB 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Dehydrogenase
MAPGIKHE_00941 2.92e-11 - - - S ko:K06889 - ko00000 Hydrolases of the alpha beta superfamily
MAPGIKHE_00942 4.55e-286 B4168_4126 - - L ko:K07493 - ko00000 Transposase
MAPGIKHE_00943 3.95e-24 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
MAPGIKHE_00944 2.84e-102 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
MAPGIKHE_00947 9.83e-187 - - - F - - - Phosphorylase superfamily
MAPGIKHE_00948 1.71e-152 - 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 HAD hydrolase, family IA, variant 1
MAPGIKHE_00949 2.48e-09 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
MAPGIKHE_00950 3.53e-24 - - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type enterochelin transport system, periplasmic component
MAPGIKHE_00951 8.97e-70 dinF - - V - - - Mate efflux family protein
MAPGIKHE_00952 1.84e-15 dinF - - V - - - Mate efflux family protein
MAPGIKHE_00954 4.55e-286 B4168_4126 - - L ko:K07493 - ko00000 Transposase
MAPGIKHE_00955 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
MAPGIKHE_00956 0.000353 - - - S - - - TraX protein
MAPGIKHE_00957 9.01e-133 - - - S - - - TraX protein
MAPGIKHE_00958 1.18e-122 thiJ 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 DJ-1 family
MAPGIKHE_00959 6.01e-189 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
MAPGIKHE_00960 2.47e-222 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MAPGIKHE_00961 6.9e-234 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MAPGIKHE_00962 2.91e-72 cas2 - - L ko:K09951 - ko00000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MAPGIKHE_00963 3.15e-173 cas6 - - S ko:K19091 - ko00000,ko01000,ko02048 CRISPR-associated endoribonuclease Cas6
MAPGIKHE_00964 0.0 csm1 - - S ko:K07016 - ko00000,ko02048 CRISPR-associated protein Csm1 family
MAPGIKHE_00965 2.57e-50 csm2 - - L ko:K19138 - ko00000,ko02048 Csm2 Type III-A
MAPGIKHE_00966 6.07e-146 csm3 - - L ko:K09002 - ko00000,ko02048 RAMP superfamily
MAPGIKHE_00967 2.1e-215 csm4 - - L ko:K19139 - ko00000,ko02048 CRISPR-associated RAMP protein, Csm4 family
MAPGIKHE_00968 6.19e-245 csm5 - - L ko:K19140 - ko00000,ko02048 CRISPR-associated RAMP protein, Csm5 family
MAPGIKHE_00969 2.48e-167 - - - S - - - Psort location Cytoplasmic, score
MAPGIKHE_00970 3.1e-182 - - - S - - - Psort location Cytoplasmic, score
MAPGIKHE_00971 1.19e-162 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MAPGIKHE_00972 6.16e-145 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MAPGIKHE_00973 2.62e-82 nylA 3.5.1.4 - J ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 ko00000,ko00001,ko01000 Belongs to the amidase family
MAPGIKHE_00975 0.0 dtpT - - E ko:K03305 - ko00000 transporter
MAPGIKHE_00976 1.27e-106 nylA 3.5.1.4 - J ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 ko00000,ko00001,ko01000 Belongs to the amidase family
MAPGIKHE_00977 5.97e-99 yckB - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
MAPGIKHE_00978 4.34e-37 yckB - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
MAPGIKHE_00979 1.11e-87 yckA - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
MAPGIKHE_00980 1.24e-29 yecS - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 amino acid transport
MAPGIKHE_00981 0.000114 sasH 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
MAPGIKHE_00982 5.67e-19 sasH 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
MAPGIKHE_00983 5.2e-77 sasH 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
MAPGIKHE_00984 1.01e-48 - 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 nucleotide catabolic process
MAPGIKHE_00985 1.2e-82 yfiF3 - - K - - - sequence-specific DNA binding
MAPGIKHE_00986 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MAPGIKHE_00987 1e-306 agcS - - E ko:K03310 - ko00000 (Alanine) symporter
MAPGIKHE_00988 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
MAPGIKHE_00989 2.08e-307 metY 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 o-acetylhomoserine
MAPGIKHE_00990 6.4e-67 - - - Q - - - phosphatase activity
MAPGIKHE_00991 3.65e-77 - - - S - - - haloacid dehalogenase-like hydrolase
MAPGIKHE_00992 2.46e-113 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MAPGIKHE_00993 3.31e-143 hsdS2 - - V - - - Type I restriction modification DNA specificity domain
MAPGIKHE_00994 4.87e-45 M1-755 - - P ko:K09155 - ko00000 Hemerythrin HHE cation binding domain protein
MAPGIKHE_00995 2.39e-123 XK27_04775 - - S ko:K09155 - ko00000 hemerythrin HHE cation binding domain
MAPGIKHE_00996 3.59e-86 XK27_04775 - - S ko:K09155 - ko00000 hemerythrin HHE cation binding domain
MAPGIKHE_00997 2.43e-194 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MAPGIKHE_00998 4.8e-223 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
MAPGIKHE_00999 7.52e-95 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MAPGIKHE_01000 1.7e-59 yktA - - S - - - Belongs to the UPF0223 family
MAPGIKHE_01001 5.9e-184 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the inositol monophosphatase superfamily
MAPGIKHE_01002 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
MAPGIKHE_01003 3.94e-202 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 phosphate
MAPGIKHE_01004 4.63e-201 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
MAPGIKHE_01005 7.15e-200 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 phosphate transport system permease
MAPGIKHE_01006 4.33e-192 pstB2 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MAPGIKHE_01007 1.24e-179 pstB1 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MAPGIKHE_01008 1.1e-147 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
MAPGIKHE_01009 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
MAPGIKHE_01010 1.32e-249 xerS - - D ko:K04763 - ko00000,ko03036 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
MAPGIKHE_01012 2.63e-240 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
MAPGIKHE_01015 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
MAPGIKHE_01016 0.0 malQ 2.4.1.25 GH77 G ko:K00705 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 4-alpha-glucanotransferase
MAPGIKHE_01017 9.49e-195 malR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
MAPGIKHE_01018 1.94e-18 malX - - G ko:K02027,ko:K15770 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 maltose binding
MAPGIKHE_01019 1.49e-82 malX - - G ko:K02027,ko:K15770 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 maltose binding
MAPGIKHE_01020 2.7e-161 malF - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
MAPGIKHE_01021 4.79e-34 tatA - - U ko:K03116,ko:K03117 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 protein secretion
MAPGIKHE_01022 3.17e-157 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MAPGIKHE_01023 0.0 ywbL - - P ko:K07243 - ko00000,ko02000 COG0672 High-affinity Fe2 Pb2 permease
MAPGIKHE_01024 2.59e-297 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 peroxidase
MAPGIKHE_01025 2.5e-199 ycdO - - P ko:K07224 - ko00000,ko02000 periplasmic lipoprotein involved in iron transport
MAPGIKHE_01026 3.24e-230 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type enterochelin transport system, periplasmic component
MAPGIKHE_01027 1.75e-174 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
MAPGIKHE_01028 5.21e-213 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MAPGIKHE_01029 1.67e-209 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MAPGIKHE_01030 8.37e-166 pulA2 3.2.1.1, 3.2.1.41 CBM48,GH13 G ko:K01176,ko:K01200 ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973 ko00000,ko00001,ko01000 belongs to the glycosyl hydrolase 13 family
MAPGIKHE_01031 1.03e-36 pulA2 3.2.1.1, 3.2.1.41 CBM48,GH13 G ko:K01176,ko:K01200 ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973 ko00000,ko00001,ko01000 belongs to the glycosyl hydrolase 13 family
MAPGIKHE_01032 5.44e-160 pulA2 3.2.1.1, 3.2.1.41 CBM48,GH13 G ko:K01176,ko:K01200 ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973 ko00000,ko00001,ko01000 belongs to the glycosyl hydrolase 13 family
MAPGIKHE_01033 4.67e-64 pulA2 3.2.1.1, 3.2.1.41 CBM48,GH13 G ko:K01176,ko:K01200 ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973 ko00000,ko00001,ko01000 belongs to the glycosyl hydrolase 13 family
MAPGIKHE_01034 0.0 - 3.5.1.28 - S ko:K01448,ko:K02395,ko:K21471 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko02035,ko03036 dextransucrase activity
MAPGIKHE_01035 0.0 lpdA 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
MAPGIKHE_01036 4.28e-275 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MAPGIKHE_01037 3.38e-232 acoB 1.2.4.1 - C ko:K00162,ko:K21417 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MAPGIKHE_01038 6.17e-236 acoA 1.2.4.1 - C ko:K00161,ko:K21416 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
MAPGIKHE_01039 0.0 - - - S - - - the current gene model (or a revised gene model) may contain a frame shift
MAPGIKHE_01040 1.4e-298 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MAPGIKHE_01041 8.14e-163 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MAPGIKHE_01042 5.21e-275 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MAPGIKHE_01043 5.27e-32 dacA1 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
MAPGIKHE_01044 1.12e-31 dacA1 3.4.16.4 - M ko:K01286 - ko00000,ko01000 Belongs to the peptidase S11 family
MAPGIKHE_01045 4.49e-162 dacA1 3.4.16.4 - M ko:K01286 - ko00000,ko01000 Belongs to the peptidase S11 family
MAPGIKHE_01046 4.34e-200 - - - S - - - Phospholipase, patatin family
MAPGIKHE_01047 4.38e-89 - - - E - - - GDSL-like protein
MAPGIKHE_01048 1.1e-38 - - - E - - - Lysophospholipase L1 and related esterases
MAPGIKHE_01049 0.0 ubiB - - S ko:K03688 - ko00000 unusual protein kinase
MAPGIKHE_01050 3.34e-52 - - - S - - - granule-associated protein
MAPGIKHE_01051 9.85e-49 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MAPGIKHE_01052 7.35e-145 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MAPGIKHE_01053 1.74e-22 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MAPGIKHE_01054 1.68e-254 XK27_12525 - - S - - - hmm pf01594
MAPGIKHE_01055 3.09e-73 - - - G - - - Belongs to the phosphoglycerate mutase family
MAPGIKHE_01056 8.95e-91 supH 3.1.3.102, 3.1.3.104 - Q ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 phosphatase activity
MAPGIKHE_01057 6.7e-54 supH - - S - - - Sucrose-6F-phosphate phosphohydrolase
MAPGIKHE_01058 3.03e-09 supH - - S - - - Sucrose-6F-phosphate phosphohydrolase
MAPGIKHE_01059 1e-40 - - - M - - - transferase activity, transferring glycosyl groups
MAPGIKHE_01060 5.99e-50 - - - L ko:K07483 - ko00000 transposase helper protein for IS981
MAPGIKHE_01061 6.9e-91 - - - L ko:K07497 - ko00000 COG2801 Transposase and inactivated derivatives
MAPGIKHE_01062 1.02e-43 - - - S - - - Glycosyltransferase like family 2
MAPGIKHE_01063 6.5e-306 cps1C - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
MAPGIKHE_01064 9.38e-235 - - - L ko:K07485 - ko00000 Transposase
MAPGIKHE_01065 3.67e-215 - - - L ko:K07481 - ko00000 transposase, IS4 family
MAPGIKHE_01066 3.42e-119 - - - V - - - VanZ like family
MAPGIKHE_01067 3.49e-71 - - - L ko:K07498 - ko00000 DDE domain
MAPGIKHE_01068 3.19e-88 - - - L ko:K07497 - ko00000 transposition
MAPGIKHE_01069 1.18e-77 - - - L ko:K07497 - ko00000 COG2801 Transposase and inactivated derivatives
MAPGIKHE_01070 1.19e-185 - - - K - - - Cell envelope-related transcriptional attenuator domain
MAPGIKHE_01071 4.32e-204 - - - G - - - Phosphodiester glycosidase
MAPGIKHE_01072 1.95e-44 - - - L - - - Transposase DDE domain
MAPGIKHE_01074 7.7e-102 - - - M - - - Glycosyl transferase, family 2
MAPGIKHE_01075 8.49e-29 - - - M - - - Glycosyltransferase WbsX
MAPGIKHE_01076 1.21e-25 - - - - - - - -
MAPGIKHE_01077 4.52e-76 - - GT2 S ko:K12990 ko02024,ko02025,map02024,map02025 ko00000,ko00001,ko01000,ko01003,ko01005 Glycosyl transferase family 2
MAPGIKHE_01078 2.18e-23 rfbF - GT2 S ko:K12990 ko02024,ko02025,map02024,map02025 ko00000,ko00001,ko01000,ko01003,ko01005 Glycosyl transferase family 2
MAPGIKHE_01079 1.59e-148 rfbC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
MAPGIKHE_01080 8.82e-152 rfbD 1.1.1.133, 5.1.3.13 - M ko:K00067,ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MAPGIKHE_01081 4.85e-23 - - - M - - - Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MAPGIKHE_01082 1.4e-76 - - - M - - - Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MAPGIKHE_01083 4.94e-37 - - - M - - - Psort location Cytoplasmic, score 8.87
MAPGIKHE_01084 1.74e-85 - - - M - - - PFAM Glycosyl transferase, group 1
MAPGIKHE_01085 2.39e-119 - - - M - - - Glycosyl transferase 4-like
MAPGIKHE_01086 5.41e-74 - - - M - - - Bacterial sugar transferase
MAPGIKHE_01087 4.64e-150 cpsD - - D - - - COG0489 ATPases involved in chromosome partitioning
MAPGIKHE_01088 1.02e-142 capA - - M - - - biosynthesis protein
MAPGIKHE_01089 4.66e-175 cpsB 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 Capsular polysaccharide biosynthesis protein
MAPGIKHE_01090 4.29e-316 cps4A - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
MAPGIKHE_01091 4.55e-286 B4168_4126 - - L ko:K07493 - ko00000 Transposase
MAPGIKHE_01092 7.19e-83 XK27_01125 - - L ko:K07484 - ko00000 COG3436 Transposase and inactivated derivatives
MAPGIKHE_01093 6.69e-27 - - - - - - - -
MAPGIKHE_01094 3.14e-165 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 purine nucleoside phosphorylase
MAPGIKHE_01095 5.19e-71 gat 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 glutamine amidotransferase
MAPGIKHE_01096 1.4e-16 gat 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 glutamine amidotransferase
MAPGIKHE_01097 5.11e-142 clcA2 - - P - - - chloride
MAPGIKHE_01098 3.56e-192 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MAPGIKHE_01099 5.38e-54 - - - S - - - Protein of unknown function (DUF1697)
MAPGIKHE_01100 2.7e-300 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
MAPGIKHE_01101 2.91e-156 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MAPGIKHE_01103 6.71e-12 - - - V - - - Glucan-binding protein C
MAPGIKHE_01104 1.53e-44 - - - V - - - Glucan-binding protein C
MAPGIKHE_01105 5.59e-145 ung2 - - L - - - Uracil-DNA glycosylase
MAPGIKHE_01106 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Dipeptidase
MAPGIKHE_01107 2.78e-37 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
MAPGIKHE_01108 5.66e-111 XK27_03610 - - K - - - Gnat family
MAPGIKHE_01109 1.15e-32 - - - L ko:K07491 - ko00000 Transposase
MAPGIKHE_01110 1.82e-73 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MAPGIKHE_01111 5.79e-39 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
MAPGIKHE_01112 3.15e-115 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MAPGIKHE_01113 8.33e-156 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
MAPGIKHE_01114 1.51e-98 XK27_09115 - - M - - - LysM domain
MAPGIKHE_01115 1.12e-119 ebsA - - S - - - Family of unknown function (DUF5322)
MAPGIKHE_01116 4.32e-299 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
MAPGIKHE_01117 1.95e-127 sipC 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
MAPGIKHE_01118 5.47e-285 XK27_05225 - - G - - - COG0457 FOG TPR repeat
MAPGIKHE_01119 1.22e-231 XK27_05220 - - S - - - permease
MAPGIKHE_01120 2.48e-120 mutX 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NTP pyrophosphohydrolases including oxidative damage repair enzymes
MAPGIKHE_01121 1.99e-209 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
MAPGIKHE_01122 7.31e-160 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
MAPGIKHE_01123 5.35e-232 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MAPGIKHE_01124 2.13e-263 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MAPGIKHE_01125 2.13e-231 - - - S - - - Calcineurin-like phosphoesterase
MAPGIKHE_01126 1.38e-174 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
MAPGIKHE_01127 0.0 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 cation transport ATPase
MAPGIKHE_01128 1.19e-89 ywiB - - S - - - Domain of unknown function (DUF1934)
MAPGIKHE_01129 9.96e-69 XK27_00115 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 acetyltransferase
MAPGIKHE_01130 5.66e-189 XK27_00835 - - S - - - hydrolases of the HAD superfamily
MAPGIKHE_01131 2.58e-294 femX 2.3.2.10, 2.3.2.16 - V ko:K05363,ko:K11693 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01011 protein involved in methicillin resistance
MAPGIKHE_01132 1.46e-196 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Metal-dependent hydrolases of the beta-lactamase superfamily I
MAPGIKHE_01133 1.57e-314 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MAPGIKHE_01134 2.49e-166 yycF - - KT ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MAPGIKHE_01135 5.43e-180 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
MAPGIKHE_01136 9.39e-192 peb1A - - ET ko:K02030,ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type amino acid transport signal transduction systems, periplasmic component domain
MAPGIKHE_01137 7.97e-157 XK27_07620 - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
MAPGIKHE_01138 4.11e-142 - - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
MAPGIKHE_01139 5.22e-181 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
MAPGIKHE_01140 4.09e-35 - - - S - - - DNA-directed RNA polymerase subunit beta
MAPGIKHE_01141 4.12e-295 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MAPGIKHE_01143 5.18e-251 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
MAPGIKHE_01144 7.13e-11 - - - G - - - Domain of unknown function (DUF4832)
MAPGIKHE_01145 5.75e-267 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MAPGIKHE_01146 2.38e-223 birA 6.3.4.15 - HK ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MAPGIKHE_01147 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MAPGIKHE_01148 1.12e-116 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
MAPGIKHE_01149 4.93e-210 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MAPGIKHE_01150 1.9e-27 WQ51_02665 - - S - - - Protein of unknown function (DUF3042)
MAPGIKHE_01153 5.73e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MAPGIKHE_01154 4.32e-279 - - - P - - - chloride
MAPGIKHE_01155 1.27e-55 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 - E ko:K00661,ko:K04092,ko:K04093,ko:K04516,ko:K14170,ko:K14187 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Chorismate mutase
MAPGIKHE_01156 0.0 eriC - - P ko:K03281 - ko00000 Chloride transporter, ClC family
MAPGIKHE_01157 1.42e-97 ykuP - - C ko:K03839 - ko00000 Flavodoxin
MAPGIKHE_01159 3.12e-162 XK27_08875 - - O - - - Zinc-dependent metalloprotease
MAPGIKHE_01160 7.51e-194 estA - CE1 S ko:K03930 - ko00000,ko01000 Putative esterase
MAPGIKHE_01161 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MAPGIKHE_01162 2.68e-174 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
MAPGIKHE_01163 6.79e-191 XK27_08840 - - S ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
MAPGIKHE_01164 2.91e-230 - - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter substrate binding protein
MAPGIKHE_01165 5.6e-17 - - - S - - - Domain of unknown function (DUF4649)
MAPGIKHE_01167 7.77e-52 crpB - - Q - - - the current gene model (or a revised gene model) may contain a frame shift
MAPGIKHE_01168 7.21e-33 crpB - - Q - - - the current gene model (or a revised gene model) may contain a frame shift
MAPGIKHE_01170 6.86e-11 crpB - - Q - - - the current gene model (or a revised gene model) may contain a frame shift
MAPGIKHE_01172 4.38e-128 - - - L ko:K07485 - ko00000 Transposase
MAPGIKHE_01173 1.77e-113 - - - L - - - Transposase
MAPGIKHE_01174 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
MAPGIKHE_01175 1.04e-239 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MAPGIKHE_01176 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
MAPGIKHE_01177 1.99e-194 XK27_00020 - - J - - - Belongs to the SUA5 family
MAPGIKHE_01178 2.76e-146 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MAPGIKHE_01179 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MAPGIKHE_01180 1.64e-57 ysdA - - L - - - Membrane
MAPGIKHE_01181 7.51e-242 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
MAPGIKHE_01182 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MAPGIKHE_01183 3.05e-169 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MAPGIKHE_01184 3.83e-229 pyrD 1.3.5.2, 1.3.98.1 - F ko:K00226,ko:K00254 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dihydroorotate to orotate
MAPGIKHE_01186 1.54e-52 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MAPGIKHE_01187 2.09e-124 ypmS - - S - - - Protein conserved in bacteria
MAPGIKHE_01188 4.24e-185 ypmR - - E - - - lipolytic protein G-D-S-L family
MAPGIKHE_01189 1.18e-190 WQ51_01275 - - S - - - DegV family
MAPGIKHE_01190 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
MAPGIKHE_01191 1.72e-94 argR2 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
MAPGIKHE_01192 9.47e-202 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
MAPGIKHE_01193 1.64e-203 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
MAPGIKHE_01194 1.72e-40 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease VII activity
MAPGIKHE_01195 9.08e-314 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MAPGIKHE_01197 3.81e-154 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MAPGIKHE_01198 9.02e-163 dnaD - - - ko:K02086 - ko00000 -
MAPGIKHE_01199 5.91e-234 metA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MAPGIKHE_01200 6.44e-122 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MAPGIKHE_01201 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease recj
MAPGIKHE_01202 1.28e-178 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
MAPGIKHE_01203 4.43e-222 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MAPGIKHE_01204 4.69e-151 XK27_05445 - - G - - - UDPglucose--hexose-1-phosphate uridylyltransferase
MAPGIKHE_01205 2.35e-285 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MAPGIKHE_01206 0.0 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
MAPGIKHE_01207 5.16e-66 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 - E ko:K01523,ko:K01814,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 phosphoribosyl-ATP diphosphatase activity
MAPGIKHE_01208 6.01e-80 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MAPGIKHE_01209 3.8e-174 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MAPGIKHE_01210 7.66e-163 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MAPGIKHE_01211 3.88e-140 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MAPGIKHE_01212 3.35e-137 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
MAPGIKHE_01213 2.07e-298 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MAPGIKHE_01214 5.67e-149 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
MAPGIKHE_01215 5.26e-234 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MAPGIKHE_01216 1.74e-251 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MAPGIKHE_01218 2.11e-113 - - - L ko:K07497 - ko00000 Integrase core domain protein
MAPGIKHE_01219 3.12e-71 - - - L ko:K07497 - ko00000 transposition
MAPGIKHE_01220 1.14e-28 - - - L - - - Transposase
MAPGIKHE_01221 8.74e-49 - - - L ko:K07483 - ko00000 transposase activity
MAPGIKHE_01222 1.5e-30 XK27_08085 - - - - - - -
MAPGIKHE_01223 1.5e-119 XK27_08080 - - G - - - Exopolysaccharide biosynthesis protein
MAPGIKHE_01224 2.04e-17 XK27_08080 - - G - - - Exopolysaccharide biosynthesis protein
MAPGIKHE_01225 2.41e-181 hisJ 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Histidinol phosphatase and related hydrolases of the PHP family
MAPGIKHE_01226 5.25e-133 - - - S - - - tigr01906
MAPGIKHE_01227 6.89e-184 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MAPGIKHE_01228 7.79e-185 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
MAPGIKHE_01229 3.81e-276 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
MAPGIKHE_01230 1.85e-285 B4168_4126 - - L ko:K07493 - ko00000 Transposase
MAPGIKHE_01233 3.31e-264 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MAPGIKHE_01234 9.6e-143 rmlC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
MAPGIKHE_01235 1.58e-205 rfbA 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MAPGIKHE_01236 3.58e-262 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 oxidoreductase
MAPGIKHE_01237 3.79e-39 zupT - - P ko:K07238 - ko00000,ko02000 transporter
MAPGIKHE_01238 2.26e-19 zupT - - P ko:K07238 - ko00000,ko02000 Mediates zinc uptake. May also transport other divalent cations
MAPGIKHE_01239 1.15e-189 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MAPGIKHE_01240 9.04e-161 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
MAPGIKHE_01241 2.86e-92 mesH - - S - - - GtrA-like protein
MAPGIKHE_01242 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MAPGIKHE_01243 1.47e-217 ybbR - - S - - - Protein conserved in bacteria
MAPGIKHE_01244 1.15e-160 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MAPGIKHE_01245 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Mur ligase, middle domain protein
MAPGIKHE_01246 1.02e-192 cobQ - - S ko:K07009 - ko00000 glutamine amidotransferase
MAPGIKHE_01247 0.0 mprF 2.3.2.3 - J ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MAPGIKHE_01248 4.3e-169 - 1.11.1.10 - S ko:K00433 - ko00000,ko01000 Alpha beta hydrolase
MAPGIKHE_01249 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 abc transporter atp-binding protein
MAPGIKHE_01250 2.24e-148 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
MAPGIKHE_01251 1.73e-231 yfmL - - L - - - DEAD DEAH box helicase
MAPGIKHE_01252 0.0 - - - L ko:K07484 - ko00000 Transposase IS66 family
MAPGIKHE_01253 1.93e-29 - - - S - - - Transposase C of IS166 homeodomain
MAPGIKHE_01254 7.19e-83 XK27_01125 - - L ko:K07484 - ko00000 COG3436 Transposase and inactivated derivatives
MAPGIKHE_01255 6.69e-27 - - - - - - - -
MAPGIKHE_01256 1.71e-21 - 6.3.2.2, 6.3.2.4 - F ko:K01919,ko:K01921 ko00270,ko00473,ko00480,ko00550,ko01100,ko01502,map00270,map00473,map00480,map00550,map01100,map01502 ko00000,ko00001,ko00002,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
MAPGIKHE_01257 0.0 gapN 1.2.1.9 - C ko:K00131 ko00010,ko00030,ko01100,ko01120,ko01200,map00010,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
MAPGIKHE_01258 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MAPGIKHE_01259 3.31e-52 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein Hpr
MAPGIKHE_01260 5.09e-283 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 Isocitrate dehydrogenase
MAPGIKHE_01261 1.22e-270 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
MAPGIKHE_01262 0.0 acnA 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MAPGIKHE_01263 3.36e-46 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
MAPGIKHE_01264 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MAPGIKHE_01265 1.99e-235 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MAPGIKHE_01267 2.28e-90 - - - L - - - Transposase (IS116 IS110 IS902 family)
MAPGIKHE_01268 1.96e-78 - - - L - - - Transposase (IS116 IS110 IS902 family)
MAPGIKHE_01269 5.92e-213 ypuA - - S - - - secreted protein
MAPGIKHE_01270 1.01e-71 ywkD - - E ko:K08234 - ko00000 COG0346 LactoylglutaTHIone lyase and related lyases
MAPGIKHE_01271 1.79e-168 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase (surface protein transpeptidase)
MAPGIKHE_01272 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MAPGIKHE_01273 2.4e-231 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
MAPGIKHE_01274 0.0 noxE - - P - - - NADH oxidase
MAPGIKHE_01275 0.0 yheS_1 - - S - - - abc transporter atp-binding protein
MAPGIKHE_01276 2.04e-77 - - - S - - - ECF-type riboflavin transporter, S component
MAPGIKHE_01277 4.85e-56 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Belongs to the pyridoxine kinase family
MAPGIKHE_01278 1.46e-112 - - - S - - - ECF-type riboflavin transporter, S component
MAPGIKHE_01280 1.79e-305 ycxD - - K - - - Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MAPGIKHE_01281 2.66e-74 nrdD_1 1.1.98.6, 1.17.4.1 - F ko:K00525,ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Ribonucleoside-triphosphate reductase
MAPGIKHE_01283 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MAPGIKHE_01284 6.18e-120 XK27_03150 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MAPGIKHE_01285 7.97e-251 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MAPGIKHE_01286 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
MAPGIKHE_01287 4.84e-161 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MAPGIKHE_01288 2.2e-223 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MAPGIKHE_01289 8.69e-256 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MAPGIKHE_01290 1.26e-107 alkD - - L - - - Dna alkylation repair
MAPGIKHE_01291 5.31e-120 pat 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 acetyltransferase
MAPGIKHE_01292 2.14e-14 - - - - - - - -
MAPGIKHE_01293 4.86e-41 - - - - - - - -
MAPGIKHE_01294 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MAPGIKHE_01295 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MAPGIKHE_01296 1.34e-168 yfnB 3.8.1.2 - E ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 hydrolase
MAPGIKHE_01297 8.89e-86 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 biotin transmembrane transporter activity
MAPGIKHE_01298 5.29e-123 - - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MAPGIKHE_01299 9.02e-177 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
MAPGIKHE_01300 1e-216 proWY - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, QAT family
MAPGIKHE_01301 8.94e-143 proWZ - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
MAPGIKHE_01302 0.0 - 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Histidine ammonia-lyase
MAPGIKHE_01303 1.2e-262 - - - S ko:K09703 - ko00000 Protein of unknown function (DUF917)
MAPGIKHE_01304 3.25e-27 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
MAPGIKHE_01305 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
MAPGIKHE_01306 4.55e-286 B4168_4126 - - L ko:K07493 - ko00000 Transposase
MAPGIKHE_01307 6.35e-155 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
MAPGIKHE_01308 1.95e-29 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
MAPGIKHE_01309 1.14e-130 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
MAPGIKHE_01311 1e-182 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
MAPGIKHE_01312 1.72e-128 - - - S ko:K01992 - ko00000,ko00002,ko02000 transport system, permease component
MAPGIKHE_01313 3.3e-131 desR - - K ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MAPGIKHE_01314 3.45e-245 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MAPGIKHE_01315 8.66e-172 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
MAPGIKHE_01316 9.82e-202 XK27_09825 - - V ko:K01990 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
MAPGIKHE_01319 3.05e-210 yocS - - S ko:K03453 - ko00000 Transporter
MAPGIKHE_01320 8.19e-107 - - - F - - - cytidine deaminase activity
MAPGIKHE_01321 3.95e-147 - - - V ko:K01992 - ko00000,ko00002,ko02000 Transporter
MAPGIKHE_01322 1.86e-61 XK27_09825 - - V ko:K01990 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
MAPGIKHE_01323 7.94e-91 XK27_09825 - - V ko:K01990 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
MAPGIKHE_01324 3.19e-17 XK27_09825 - - V ko:K01990 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
MAPGIKHE_01327 1.61e-120 - - - S ko:K06940 - ko00000 Fe-S-cluster oxidoreductase
MAPGIKHE_01328 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
MAPGIKHE_01329 3.5e-170 yxdL - - V ko:K02003,ko:K19083 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MAPGIKHE_01330 1.2e-215 - - - T - - - Histidine kinase
MAPGIKHE_01331 3.54e-157 graR - - KT ko:K19082 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MAPGIKHE_01332 1.22e-100 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MAPGIKHE_01333 2.62e-07 pbuX - - F ko:K16169 - ko00000,ko02000 xanthine permease
MAPGIKHE_01334 1.3e-191 pbuX - - F ko:K16169 - ko00000,ko02000 xanthine permease
MAPGIKHE_01335 3.14e-46 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
MAPGIKHE_01336 9.26e-317 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
MAPGIKHE_01337 5.51e-239 msrA 1.8.4.11, 1.8.4.12 - O ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MAPGIKHE_01338 1.91e-297 brnQ - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
MAPGIKHE_01339 1.01e-61 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
MAPGIKHE_01340 5.58e-76 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
MAPGIKHE_01341 3.31e-35 csbD - - K - - - CsbD-like
MAPGIKHE_01342 4.6e-294 yfnA - - E ko:K03294 - ko00000 amino acid
MAPGIKHE_01343 8.72e-95 - - - S - - - dextransucrase activity
MAPGIKHE_01344 7.05e-150 - - - S - - - dextransucrase activity
MAPGIKHE_01345 1.32e-176 - - - S - - - dextransucrase activity
MAPGIKHE_01346 4.38e-40 - - - L ko:K07497 - ko00000 Integrase core domain protein
MAPGIKHE_01349 1.81e-173 tcyC2 - - E ko:K10010,ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
MAPGIKHE_01350 2.02e-148 - - - P ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, permease protein
MAPGIKHE_01351 6.18e-144 - - - P ko:K16958 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
MAPGIKHE_01352 8.82e-207 - - - ET ko:K16957 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
MAPGIKHE_01353 9.85e-217 - 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen decarboxylase (URO-D)
MAPGIKHE_01354 4.55e-286 B4168_4126 - - L ko:K07493 - ko00000 Transposase
MAPGIKHE_01355 7.97e-108 gpo 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
MAPGIKHE_01356 3.84e-54 - - - S - - - Sugar efflux transporter for intercellular exchange
MAPGIKHE_01357 3.87e-28 - - - P ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
MAPGIKHE_01358 1.16e-120 - - - V ko:K02003 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
MAPGIKHE_01359 4.35e-108 - - - K - - - WHG domain
MAPGIKHE_01360 1.31e-85 ydhF - - S - - - Aldo keto reductase
MAPGIKHE_01361 8.66e-91 ydhF - - S - - - Aldo keto reductase
MAPGIKHE_01362 2.43e-09 ydhF - - S - - - Aldo keto reductase
MAPGIKHE_01363 8.51e-143 XK27_02070 - - S ko:K07078 - ko00000 nitroreductase
MAPGIKHE_01364 9.62e-193 catE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
MAPGIKHE_01365 2.96e-100 ywnA_2 - - K - - - Transcriptional regulator
MAPGIKHE_01366 4.34e-202 - - - E - - - Alpha/beta hydrolase of unknown function (DUF915)
MAPGIKHE_01367 1.56e-266 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MAPGIKHE_01368 2.02e-143 ydgI - - C - - - Nitroreductase
MAPGIKHE_01369 5.82e-130 - - - S - - - Protein of unknown function (DUF1275)
MAPGIKHE_01370 2.42e-07 - - - S - - - Protein of unknown function (DUF1275)
MAPGIKHE_01371 3.88e-204 yvgN - - C - - - reductase
MAPGIKHE_01372 8.78e-228 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
MAPGIKHE_01373 0.0 XK27_07020 - - S - - - Belongs to the UPF0371 family
MAPGIKHE_01375 2.62e-49 BP1961 - - P - - - nitric oxide dioxygenase activity
MAPGIKHE_01376 2.55e-70 saeR - - K ko:K10682 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
MAPGIKHE_01377 1.27e-84 - - - S - - - Signal peptide protein, YSIRK family
MAPGIKHE_01379 5.86e-79 - - - - - - - -
MAPGIKHE_01380 0.0 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MAPGIKHE_01381 6.72e-102 - - - - - - - -
MAPGIKHE_01382 1.08e-14 - - - IQ - - - PFAM AMP-dependent synthetase and ligase
MAPGIKHE_01383 1.32e-09 - - - IQ - - - PFAM AMP-dependent synthetase and ligase
MAPGIKHE_01384 4.28e-87 - - - E - - - LysE type translocator
MAPGIKHE_01385 6.23e-11 - - - - - - - -
MAPGIKHE_01386 3.06e-12 - - - - - - - -
MAPGIKHE_01387 0.0 - - - M - - - family 8
MAPGIKHE_01388 3.86e-222 hrtB - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
MAPGIKHE_01389 1.33e-151 - - - V ko:K02003 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
MAPGIKHE_01390 2.97e-23 - - - - - - - -
MAPGIKHE_01391 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 ATPase involved in DNA repair
MAPGIKHE_01392 2.18e-291 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
MAPGIKHE_01393 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 -beta-galactosidase
MAPGIKHE_01394 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 transporter
MAPGIKHE_01395 3.66e-252 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
MAPGIKHE_01396 1.73e-247 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
MAPGIKHE_01397 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDPglucose--hexose-1-phosphate uridylyltransferase
MAPGIKHE_01398 1.91e-281 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MAPGIKHE_01399 4.55e-286 B4168_4126 - - L ko:K07493 - ko00000 Transposase
MAPGIKHE_01400 3.3e-235 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
MAPGIKHE_01401 1.7e-13 - - - L ko:K07497 - ko00000 Integrase core domain protein
MAPGIKHE_01402 4.87e-246 - - - M ko:K08643 - ko00000,ko01000,ko01002 translation initiation factor activity
MAPGIKHE_01403 1.6e-51 zmpB - - M ko:K08643 - ko00000,ko01000,ko01002 M26 IgA1-specific Metallo-endopeptidase C-terminal region
MAPGIKHE_01404 4.48e-24 zmpB - - M ko:K08643 - ko00000,ko01000,ko01002 M26 IgA1-specific Metallo-endopeptidase C-terminal region
MAPGIKHE_01405 3.04e-121 ndvA - - V ko:K06147 - ko00000,ko02000 abc transporter atp-binding protein
MAPGIKHE_01406 7.03e-48 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 abc transporter atp-binding protein
MAPGIKHE_01407 0.0 gshF 6.3.2.2 - H ko:K01919,ko:K16786,ko:K16787 ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the glutamate--cysteine ligase type 1 family
MAPGIKHE_01408 1.69e-93 - - - L - - - Transposase
MAPGIKHE_01409 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
MAPGIKHE_01410 6.7e-240 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
MAPGIKHE_01411 2.7e-172 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
MAPGIKHE_01412 6.44e-122 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MAPGIKHE_01415 8.07e-148 vraR - - K ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MAPGIKHE_01416 4.58e-224 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MAPGIKHE_01417 5.15e-23 yvqF - - KT ko:K11622 ko02020,map02020 ko00000,ko00001 membrane
MAPGIKHE_01418 1.56e-119 yvqF - - KT ko:K11622 ko02020,map02020 ko00000,ko00001 membrane
MAPGIKHE_01419 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
MAPGIKHE_01420 6.37e-169 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
MAPGIKHE_01421 1.1e-314 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MAPGIKHE_01422 1.55e-223 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MAPGIKHE_01423 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MAPGIKHE_01424 2.77e-61 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-directed 5'-3' RNA polymerase activity
MAPGIKHE_01425 8.75e-145 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
MAPGIKHE_01426 3.27e-311 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MAPGIKHE_01427 2.49e-191 XK27_02985 - - S - - - overlaps another CDS with the same product name
MAPGIKHE_01428 7.44e-187 - - - S - - - overlaps another CDS with the same product name
MAPGIKHE_01429 5.73e-82 ytrA - - K ko:K07979 - ko00000,ko03000 Transcriptional
MAPGIKHE_01430 2.78e-157 skfE - - V ko:K01990 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
MAPGIKHE_01431 2.73e-172 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPase activity
MAPGIKHE_01432 2.87e-218 amiF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MAPGIKHE_01433 8.41e-260 amiE - - P ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MAPGIKHE_01434 8.16e-213 amiD - - P ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
MAPGIKHE_01435 0.0 amiC - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
MAPGIKHE_01436 0.0 amiA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, family 5
MAPGIKHE_01437 8.82e-31 - - - - - - - -
MAPGIKHE_01438 1.41e-223 - - - L - - - the current gene model (or a revised gene model) may contain a frame shift
MAPGIKHE_01439 0.0 amiA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, family 5
MAPGIKHE_01440 1.72e-30 amiF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MAPGIKHE_01441 1.18e-60 amiF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MAPGIKHE_01442 1.55e-29 tatD - - L ko:K03424 - ko00000,ko01000 Hydrolase, tatd
MAPGIKHE_01443 3.41e-277 oxlT - - P ko:K08177 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
MAPGIKHE_01444 1.16e-110 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
MAPGIKHE_01445 3.49e-30 - - - L - - - Transposase
MAPGIKHE_01446 2.04e-52 - - - L ko:K07483 - ko00000 transposase activity
MAPGIKHE_01447 4.67e-233 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
MAPGIKHE_01448 7.67e-222 yjbO 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
MAPGIKHE_01449 1.1e-193 nadK 2.7.1.23 - H ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MAPGIKHE_01450 5.42e-155 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 Gtp pyrophosphokinase
MAPGIKHE_01451 5.5e-134 yjbK - - S - - - Adenylate cyclase
MAPGIKHE_01452 2.07e-226 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MAPGIKHE_01453 1.12e-264 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
MAPGIKHE_01454 1.77e-78 XK27_04120 - - S - - - Putative amino acid metabolism
MAPGIKHE_01455 5.23e-151 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MAPGIKHE_01456 2.71e-168 - - - T ko:K07010 - ko00000,ko01002 peptidase C26
MAPGIKHE_01457 2.79e-155 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
MAPGIKHE_01458 0.0 rgpF - - M ko:K07272 - ko00000,ko01000,ko01003,ko01005 Rhamnan synthesis protein F
MAPGIKHE_01459 9.33e-252 rgpE - GT2 M ko:K12998 - ko00000,ko01000,ko01003,ko01005 COG0463 Glycosyltransferases involved in cell wall biogenesis
MAPGIKHE_01460 4.93e-286 rgpD 3.6.3.40 - P ko:K01990,ko:K09691,ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
MAPGIKHE_01461 3.89e-184 rgpC - - GM ko:K01992 - ko00000,ko00002,ko02000 Transport permease protein
MAPGIKHE_01462 7.75e-232 rgpB - GT2 M ko:K12997 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
MAPGIKHE_01463 1.03e-288 rgpA - GT4 M ko:K12996 - ko00000,ko01000,ko01003,ko01005 Domain of unknown function (DUF1972)
MAPGIKHE_01464 4.6e-171 - - - S - - - Predicted membrane protein (DUF2142)
MAPGIKHE_01465 4.01e-238 tagF 2.7.8.12 - M ko:K09809,ko:K19046 - ko00000,ko01000,ko02048 Glycosyl transferase, family 2
MAPGIKHE_01466 1.91e-281 rgpX3 - - S - - - polysaccharide biosynthetic process
MAPGIKHE_01467 3.81e-64 - - - S ko:K09153 - ko00000 Uncharacterized conserved protein (DUF2304)
MAPGIKHE_01468 1.69e-161 - - - S - - - Glycosyl transferase family 2
MAPGIKHE_01469 1.71e-206 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MAPGIKHE_01470 8.65e-193 - - - S - - - Glucosyl transferase GtrII
MAPGIKHE_01471 4.24e-42 - - - S - - - Glucosyl transferase GtrII
MAPGIKHE_01472 9.94e-214 yfdH - GT2 M ko:K12999,ko:K20534 - ko00000,ko01000,ko01003,ko01005,ko02000 COG0463, glycosyltransferases involved in cell wall biogenesis
MAPGIKHE_01473 4.86e-74 yitW - - K - - - metal-sulfur cluster biosynthetic enzyme
MAPGIKHE_01474 3.03e-257 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MAPGIKHE_01475 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MAPGIKHE_01476 1.9e-27 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
MAPGIKHE_01477 4.07e-175 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
MAPGIKHE_01478 9.57e-268 arcT - - E - - - Aminotransferase
MAPGIKHE_01479 1.53e-175 XK27_04395 - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter
MAPGIKHE_01480 3.75e-182 XK27_04395 - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
MAPGIKHE_01481 1.24e-108 XK27_04400 3.6.1.55 - F ko:K03574,ko:K12944 - ko00000,ko01000,ko03400 Nudix family
MAPGIKHE_01482 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MAPGIKHE_01483 9.09e-88 - - - S ko:K07052 - ko00000 CAAX amino terminal protease family protein
MAPGIKHE_01484 1.27e-39 - - - S ko:K07052 - ko00000 CAAX amino terminal protease family protein
MAPGIKHE_01485 0.0 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type amino acid transport signal transduction systems periplasmic component domain
MAPGIKHE_01486 7.15e-176 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 abc transporter atp-binding protein
MAPGIKHE_01487 1.84e-24 XK27_00735 - - - - - - -
MAPGIKHE_01488 1.9e-316 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MAPGIKHE_01489 8.41e-11 - - - S - - - Protein of unknown function (DUF4044)
MAPGIKHE_01490 3.68e-172 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
MAPGIKHE_01492 1.25e-85 - - - Q ko:K02614 ko00360,map00360 ko00000,ko00001,ko01000 protein possibly involved in aromatic compounds catabolism
MAPGIKHE_01493 2.59e-69 ycaO - - O ko:K06889,ko:K07397,ko:K09136 - ko00000,ko03009 OsmC-like protein
MAPGIKHE_01495 3.12e-195 - - - EG - - - Permeases of the drug metabolite transporter (DMT) superfamily
MAPGIKHE_01497 0.0 - - - L ko:K07484 - ko00000 Transposase IS66 family
MAPGIKHE_01498 1.93e-29 - - - S - - - Transposase C of IS166 homeodomain
MAPGIKHE_01499 7.19e-83 XK27_01125 - - L ko:K07484 - ko00000 COG3436 Transposase and inactivated derivatives
MAPGIKHE_01500 6.69e-27 - - - - - - - -
MAPGIKHE_01501 6.13e-148 serB 3.1.3.3 - E ko:K01079 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01009 phosphoserine phosphatase
MAPGIKHE_01502 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MAPGIKHE_01503 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MAPGIKHE_01504 1.07e-141 - - - S - - - IA, variant 1
MAPGIKHE_01505 4.46e-151 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 effector of murein hydrolase
MAPGIKHE_01506 2.14e-76 lrgA - - S ko:K06518 - ko00000,ko02000 Effector of murein hydrolase LrgA
MAPGIKHE_01508 1.02e-78 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
MAPGIKHE_01509 2.85e-71 ogt 2.1.1.63, 3.2.2.20 - L ko:K00567,ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 methylated-DNA-[protein]-cysteine S-methyltransferase activity
MAPGIKHE_01510 2.15e-280 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MAPGIKHE_01511 2.3e-135 - - - M - - - Acetyltransferase (GNAT) domain
MAPGIKHE_01512 3.61e-267 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MAPGIKHE_01513 7.31e-125 - - - GK - - - ROK family
MAPGIKHE_01514 9.31e-93 gloA 4.4.1.5 - E ko:K01759,ko:K15772 ko00620,ko02010,map00620,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Lactoylglutathione lyase
MAPGIKHE_01515 1.88e-86 XK27_08050 - - O - - - stress-induced mitochondrial fusion
MAPGIKHE_01516 1.99e-61 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 HflC and HflK could regulate a protease
MAPGIKHE_01517 1.85e-05 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 HflC and HflK could regulate a protease
MAPGIKHE_01518 3.44e-263 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 spermidine putrescine ABC transporter
MAPGIKHE_01519 1.79e-171 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type spermidine putrescine transport system, permease component II
MAPGIKHE_01520 2e-179 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type spermidine putrescine transport system, permease component I
MAPGIKHE_01521 1.38e-272 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MAPGIKHE_01522 4.06e-219 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
MAPGIKHE_01523 9.28e-113 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MAPGIKHE_01524 1.05e-81 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MAPGIKHE_01525 0.0 amy 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
MAPGIKHE_01526 1.29e-188 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MAPGIKHE_01527 1.17e-129 folE 3.5.4.16 - F ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 gtp cyclohydrolase
MAPGIKHE_01528 0.0 ydaO - - E - - - amino acid
MAPGIKHE_01529 1.93e-304 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
MAPGIKHE_01530 9.09e-50 ylqC - - L ko:K06960 - ko00000 Belongs to the UPF0109 family
MAPGIKHE_01531 2.19e-56 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
MAPGIKHE_01532 4.17e-217 tehB 2.1.1.265 - PQ ko:K16868 - ko00000,ko01000 tellurite resistance protein tehb
MAPGIKHE_01533 9.9e-202 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
MAPGIKHE_01534 1.22e-97 - - - S - - - QueT transporter
MAPGIKHE_01535 4.27e-11 - - - L - - - Transposase DDE domain
MAPGIKHE_01536 1.43e-115 - - - L - - - Transposase DDE domain
MAPGIKHE_01537 7.79e-237 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MAPGIKHE_01538 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MAPGIKHE_01539 4.63e-110 ccl - - S - - - cog cog4708
MAPGIKHE_01540 9.7e-210 rbn - - E ko:K07058 - ko00000 Belongs to the UPF0761 family
MAPGIKHE_01541 2.86e-211 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
MAPGIKHE_01542 1.09e-294 ytoI - - K - - - transcriptional regulator containing CBS domains
MAPGIKHE_01543 5.58e-126 XK27_07830 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase GNAT Family
MAPGIKHE_01544 4.48e-297 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MAPGIKHE_01545 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
MAPGIKHE_01546 3.38e-137 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
MAPGIKHE_01547 4.16e-182 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
MAPGIKHE_01548 1.25e-97 nodB3 - - G - - - polysaccharide deacetylase
MAPGIKHE_01549 6.08e-63 nodB3 - - G - - - polysaccharide deacetylase
MAPGIKHE_01550 1.75e-180 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase
MAPGIKHE_01551 1.68e-55 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
MAPGIKHE_01552 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MAPGIKHE_01553 2.92e-203 corA - - P - - - CorA-like protein
MAPGIKHE_01554 1.07e-82 yjqA - - S - - - Bacterial PH domain
MAPGIKHE_01555 8.85e-127 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter
MAPGIKHE_01556 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MAPGIKHE_01557 8.85e-136 ywaF - - S - - - Integral membrane protein (intg_mem_TP0381)
MAPGIKHE_01558 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MAPGIKHE_01562 2.23e-198 cjaA - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
MAPGIKHE_01563 8.19e-174 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 abc transporter atp-binding protein
MAPGIKHE_01564 4.02e-148 glnP7 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter (Permease
MAPGIKHE_01565 1e-147 glnP9 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter (Permease
MAPGIKHE_01566 3.92e-247 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
MAPGIKHE_01567 9.48e-43 copZ - - P - - - Heavy metal-associated domain protein
MAPGIKHE_01568 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
MAPGIKHE_01569 4.28e-97 copY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor, CopY TcrY family
MAPGIKHE_01570 5.63e-180 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
MAPGIKHE_01571 2.02e-290 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MAPGIKHE_01572 1.46e-128 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the TrpF family
MAPGIKHE_01573 1.6e-172 trpC 4.1.1.48 - E ko:K01609 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
MAPGIKHE_01574 2.69e-231 trpD 2.4.2.18, 4.1.3.27 - F ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MAPGIKHE_01575 4.79e-134 trpG 4.1.3.27 - EH ko:K01658 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 anthranilate
MAPGIKHE_01576 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MAPGIKHE_01577 2.24e-55 MA20_20425 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 - E ko:K00800,ko:K03785,ko:K04092,ko:K04782 ko00400,ko01053,ko01100,ko01110,ko01130,ko01230,map00400,map01053,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Chorismate mutase
MAPGIKHE_01578 1.23e-68 - - - - - - - -
MAPGIKHE_01579 0.0 ctpE - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
MAPGIKHE_01580 3.34e-36 - - - - - - - -
MAPGIKHE_01582 0.0 - 2.4.1.5 GH13 G ko:K00689 ko00500,ko02020,map00500,map02020 ko00000,ko00001,ko01000 Glycosyl hydrolase family 70
MAPGIKHE_01583 2.36e-36 - - - - - - - -
MAPGIKHE_01584 5.31e-59 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MAPGIKHE_01585 2.2e-61 - - - L - - - transposase activity
MAPGIKHE_01586 5e-131 - - - K - - - transcriptional regulator, MerR family
MAPGIKHE_01587 4.96e-11 - - - K - - - transcriptional regulator, MerR family
MAPGIKHE_01588 3.45e-131 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
MAPGIKHE_01589 1.41e-80 WQ51_02910 - - S - - - Protein of unknown function, DUF536
MAPGIKHE_01590 5.02e-82 XK27_02560 - - S - - - cog cog2151
MAPGIKHE_01591 0.0 ilvD 4.2.1.9 - E ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the IlvD Edd family
MAPGIKHE_01592 3.35e-289 ytfP - - S ko:K07007 - ko00000 Flavoprotein
MAPGIKHE_01594 1.46e-154 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MAPGIKHE_01595 8.46e-197 ytmP - - M - - - Phosphotransferase
MAPGIKHE_01596 4.26e-229 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
MAPGIKHE_01597 1.68e-168 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
MAPGIKHE_01598 1.02e-93 hit - - FG ko:K02503 - ko00000,ko04147 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
MAPGIKHE_01599 5.24e-11 - - - - - - - -
MAPGIKHE_01600 1.87e-66 - - - S - - - CD20-like family
MAPGIKHE_01601 1.09e-124 - - - - - - - -
MAPGIKHE_01603 0.0 clpL - - O ko:K04086 - ko00000,ko03110 ATP-dependent Clp protease ATP-binding subunit
MAPGIKHE_01604 1.28e-255 ylbM - - S - - - Belongs to the UPF0348 family
MAPGIKHE_01605 4.61e-178 XK27_06665 - - Q - - - Methyltransferase domain protein
MAPGIKHE_01606 9.81e-77 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MAPGIKHE_01607 2.01e-139 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
MAPGIKHE_01608 5.51e-153 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MAPGIKHE_01609 1.59e-65 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein
MAPGIKHE_01610 2.78e-275 yqeH - - S ko:K06948 - ko00000,ko03009 in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
MAPGIKHE_01611 1.84e-127 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
MAPGIKHE_01612 2.86e-195 - - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MAPGIKHE_01613 5.45e-74 - - - - - - - -
MAPGIKHE_01614 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MAPGIKHE_01615 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MAPGIKHE_01616 7.49e-64 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MAPGIKHE_01617 4.51e-35 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 transferase activity, transferring glycosyl groups
MAPGIKHE_01618 3.8e-43 - - - M - - - lipopolysaccharide 3-alpha-galactosyltransferase activity
MAPGIKHE_01619 2.05e-76 ascB 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MAPGIKHE_01620 1.63e-232 ascB 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MAPGIKHE_01621 4.82e-126 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MAPGIKHE_01622 8.09e-120 metQ - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
MAPGIKHE_01623 4.12e-27 metQ - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
MAPGIKHE_01624 1.05e-130 pncA - - Q ko:K16788 - ko00000,ko02000 isochorismatase
MAPGIKHE_01625 6.34e-182 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
MAPGIKHE_01626 3.71e-303 aspC 2.6.1.2, 2.6.1.66 - E ko:K14260 ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
MAPGIKHE_01627 7.54e-99 XK27_03180 - - T - - - universal stress protein
MAPGIKHE_01630 6.98e-202 pflA 1.97.1.4 - C ko:K04069 - ko00000,ko01000 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MAPGIKHE_01631 4.55e-286 B4168_4126 - - L ko:K07493 - ko00000 Transposase
MAPGIKHE_01632 4.55e-286 B4168_4126 - - L ko:K07493 - ko00000 Transposase
MAPGIKHE_01633 2.02e-304 hlyX - - S ko:K03699 - ko00000,ko02042 COG1253 Hemolysins and related proteins containing CBS domains
MAPGIKHE_01634 1.29e-185 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
MAPGIKHE_01635 0.0 nhaP1 - - P ko:K03316 - ko00000 NhaP-type Na H and K H antiporters
MAPGIKHE_01637 9e-127 mraW1 - - J - - - (SAM)-dependent
MAPGIKHE_01638 1.51e-236 ytqA - - S ko:K07139 - ko00000 radical SAM protein
MAPGIKHE_01639 9.31e-251 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
MAPGIKHE_01640 4.58e-114 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MAPGIKHE_01641 9.01e-121 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
MAPGIKHE_01642 4.78e-220 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MAPGIKHE_01643 3.45e-12 - - - S - - - Protein of unknown function (DUF4059)
MAPGIKHE_01644 1.61e-168 tcyN 3.6.3.21 - E ko:K02028,ko:K10010,ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
MAPGIKHE_01645 1.95e-223 yxeN - - P ko:K02029,ko:K16959,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
MAPGIKHE_01646 7.04e-193 - - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC-type amino acid transport signal transduction systems, periplasmic component domain
MAPGIKHE_01648 8.1e-261 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MAPGIKHE_01649 0.0 pflB 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 formate acetyltransferase'
MAPGIKHE_01650 1.98e-83 cah 4.2.1.1 - P ko:K01674 ko00910,map00910 ko00000,ko00001,ko01000 carbonic anhydrase
MAPGIKHE_01651 4.39e-59 cah 4.2.1.1 - P ko:K01674 ko00910,map00910 ko00000,ko00001,ko01000 carbonic anhydrase
MAPGIKHE_01652 8.95e-110 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MAPGIKHE_01653 1.11e-67 hsdS_1 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 type I restriction modification DNA specificity domain
MAPGIKHE_01654 5.36e-102 - - - D - - - nuclear chromosome segregation
MAPGIKHE_01655 4.05e-164 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
MAPGIKHE_01656 8.05e-149 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
MAPGIKHE_01657 2.76e-42 - - - - - - - -
MAPGIKHE_01658 6.86e-234 - - - V - - - COG1680 Beta-lactamase class C and other penicillin binding proteins
MAPGIKHE_01659 1.05e-175 cppA - - E - - - CppA N-terminal
MAPGIKHE_01660 7.59e-212 gla - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
MAPGIKHE_01661 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
MAPGIKHE_01664 1.31e-63 spiA - - K ko:K18831 - ko00000,ko02048,ko03000 sequence-specific DNA binding
MAPGIKHE_01665 1.11e-210 blpT - - - - - - -
MAPGIKHE_01666 3.22e-156 - - - L - - - Transposase
MAPGIKHE_01667 5.13e-211 - - - L ko:K07497 - ko00000 integrase core domain
MAPGIKHE_01671 0.000313 - - - - - - - -
MAPGIKHE_01672 1.08e-34 - - - S - - - Bacteriocin class II with double-glycine leader peptide
MAPGIKHE_01675 2.22e-174 agrA - - KT ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 phosphorelay signal transduction system
MAPGIKHE_01676 5.99e-303 blpH 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 protein histidine kinase activity
MAPGIKHE_01678 5.03e-311 mesE - - M ko:K20345 ko02024,map02024 ko00000,ko00001,ko02000 Transport protein ComB
MAPGIKHE_01679 0.0 comA - - V ko:K06148,ko:K20344 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
MAPGIKHE_01681 3.34e-178 mdlB - - V ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
MAPGIKHE_01682 8.21e-199 mdlB - - V ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
MAPGIKHE_01683 0.0 mdlA - - V ko:K06148,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
MAPGIKHE_01685 2.82e-122 XK27_09885 - - V - - - Glycopeptide antibiotics resistance protein
MAPGIKHE_01686 4.54e-285 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
MAPGIKHE_01687 3.68e-134 yutD - - J - - - protein conserved in bacteria
MAPGIKHE_01688 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
MAPGIKHE_01690 2.75e-304 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MAPGIKHE_01691 8.08e-236 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MAPGIKHE_01692 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 penicillin-binding protein
MAPGIKHE_01693 3.89e-62 ftsL - - D - - - cell division protein FtsL
MAPGIKHE_01694 4.73e-244 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MAPGIKHE_01695 3.08e-118 - - - - - - - -
MAPGIKHE_01696 5.38e-55 - - - - - - - -
MAPGIKHE_01698 1.58e-42 - - - J - - - Protein of unknown function (DUF805)
MAPGIKHE_01699 1.3e-34 - - - D - - - nuclear chromosome segregation
MAPGIKHE_01700 2.87e-288 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MAPGIKHE_01701 2.47e-182 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MAPGIKHE_01702 0.0 XK27_00765 - - - ko:K01992 - ko00000,ko00002,ko02000 -
MAPGIKHE_01703 4.4e-117 ecsA_2 - - V ko:K01990 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
MAPGIKHE_01704 1.92e-60 ecsA_2 - - V ko:K01990 - ko00000,ko00002,ko02000 ATPase activity
MAPGIKHE_01705 1.75e-135 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
MAPGIKHE_01706 6.65e-15 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
MAPGIKHE_01707 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
MAPGIKHE_01708 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
MAPGIKHE_01709 1.15e-79 - - - S - - - membrane
MAPGIKHE_01710 1.34e-32 - - - KT - - - response to antibiotic
MAPGIKHE_01711 5.16e-20 - - - KT - - - response to antibiotic
MAPGIKHE_01712 1.98e-125 yebC - - M - - - Membrane
MAPGIKHE_01713 1.77e-24 yebC - - M - - - Membrane
MAPGIKHE_01714 0.0 - - - S - - - hydrolases of the HAD superfamily
MAPGIKHE_01715 8.08e-223 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
MAPGIKHE_01716 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MAPGIKHE_01717 1.72e-246 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MAPGIKHE_01718 1.23e-80 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MAPGIKHE_01719 2.89e-251 aroG 2.5.1.54 - E ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 ko00000,ko00001,ko00002,ko01000 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MAPGIKHE_01720 2.03e-251 aroH 2.5.1.54 - E ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 ko00000,ko00001,ko00002,ko01000 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MAPGIKHE_01721 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MAPGIKHE_01723 2.07e-239 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
MAPGIKHE_01724 2.77e-219 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 Fructokinase
MAPGIKHE_01725 0.0 scrA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
MAPGIKHE_01726 0.0 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
MAPGIKHE_01727 7.4e-227 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional
MAPGIKHE_01728 2.67e-96 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MAPGIKHE_01729 9.01e-81 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 protein conserved in bacteria
MAPGIKHE_01730 1.22e-126 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MAPGIKHE_01731 1.43e-109 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
MAPGIKHE_01732 2.05e-256 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Belongs to the peptidase M24B family
MAPGIKHE_01736 7.37e-25 - - - V ko:K01990,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 'abc transporter, ATP-binding protein
MAPGIKHE_01739 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MAPGIKHE_01740 4.94e-217 corA - - P ko:K03284 - ko00000,ko02000 COG0598 Mg2 and Co2 transporters
MAPGIKHE_01741 5.06e-160 - - - S - - - Pfam PF06570
MAPGIKHE_01743 2.03e-47 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MAPGIKHE_01744 2.07e-118 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MAPGIKHE_01745 3.11e-62 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
MAPGIKHE_01746 1.77e-51 XK27_05745 - - - - - - -
MAPGIKHE_01747 5.55e-292 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific adenine glycosylase
MAPGIKHE_01751 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MAPGIKHE_01752 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MAPGIKHE_01753 3.39e-121 cvpA - - S ko:K03558 - ko00000 toxin biosynthetic process
MAPGIKHE_01754 5.78e-19 - - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MAPGIKHE_01755 4.7e-206 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MAPGIKHE_01756 3.19e-146 spi 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
MAPGIKHE_01757 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MAPGIKHE_01758 1.99e-63 azlD - - E - - - branched-chain amino acid
MAPGIKHE_01759 2.44e-148 XK27_12120 - - E - - - AzlC protein
MAPGIKHE_01760 1.15e-238 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MAPGIKHE_01761 1.54e-96 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
MAPGIKHE_01762 2.39e-156 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214, inactive homolog of metal-dependent proteases
MAPGIKHE_01763 6.45e-45 ykzG - - S - - - Belongs to the UPF0356 family
MAPGIKHE_01764 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MAPGIKHE_01765 9.78e-55 sle1 3.5.1.28 CBM50 M ko:K22409 - ko00000,ko01000 CHAP domain protein
MAPGIKHE_01766 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
MAPGIKHE_01767 1.12e-83 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 Transcriptional regulator
MAPGIKHE_01768 2.17e-113 - - - S - - - Fusaric acid resistance protein-like
MAPGIKHE_01769 1.82e-17 - - - - - - - -
MAPGIKHE_01770 2.05e-42 - - - - - - - -
MAPGIKHE_01771 1.11e-281 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
MAPGIKHE_01772 8.75e-54 - - - L ko:K07491 - ko00000 COG1943 Transposase and inactivated derivatives
MAPGIKHE_01773 1.68e-55 - - - L - - - Transposase
MAPGIKHE_01774 5.99e-55 - - - L ko:K07497 - ko00000 Integrase core domain protein
MAPGIKHE_01775 1.64e-35 - - - L ko:K07497 - ko00000 Integrase core domain protein
MAPGIKHE_01776 1.11e-240 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MAPGIKHE_01777 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MAPGIKHE_01778 2.7e-104 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MAPGIKHE_01779 4.89e-91 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MAPGIKHE_01780 8.93e-184 purR - - F ko:K09685 - ko00000,ko03000 operon repressor
MAPGIKHE_01781 2.78e-228 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 3'-5' exoribonuclease yhaM
MAPGIKHE_01782 1.33e-235 rmuC - - S ko:K09760 - ko00000 RmuC domain protein
MAPGIKHE_01783 2.73e-153 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
MAPGIKHE_01784 2.76e-153 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
MAPGIKHE_01785 3.08e-208 rsgA 3.1.3.100 - G ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MAPGIKHE_01787 2.6e-200 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MAPGIKHE_01788 1.27e-128 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MAPGIKHE_01789 1.83e-184 tatD - - L ko:K03424 - ko00000,ko01000 Hydrolase, tatd
MAPGIKHE_01790 1.62e-98 yneT - - S ko:K06929 - ko00000 CoA-binding protein
MAPGIKHE_01791 5.36e-68 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
MAPGIKHE_01792 5.24e-185 - - - S - - - Macro domain protein
MAPGIKHE_01793 1.14e-14 yneP - - L ko:K07107 - ko00000,ko01000 thioesterase
MAPGIKHE_01794 1.18e-72 bta 1.8.1.8 - CO ko:K03671,ko:K03672 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko01000,ko03110 cell redox homeostasis
MAPGIKHE_01797 3.46e-289 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MAPGIKHE_01798 1.37e-45 - - - L ko:K07491 - ko00000 Transposase
MAPGIKHE_01799 9.33e-20 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L34
MAPGIKHE_01800 9.39e-235 jag - - S ko:K06346 - ko00000 RNA-binding protein
MAPGIKHE_01801 1.8e-180 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MAPGIKHE_01802 3.95e-71 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MAPGIKHE_01803 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Argininosuccinate lyase
MAPGIKHE_01804 1.3e-293 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
MAPGIKHE_01805 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MAPGIKHE_01806 2.22e-108 amiA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 transmembrane transport
MAPGIKHE_01807 1.83e-26 amiA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 transmembrane transport
MAPGIKHE_01808 1e-180 amiA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, family 5
MAPGIKHE_01809 4.43e-26 amiA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, family 5
MAPGIKHE_01810 2.36e-156 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MAPGIKHE_01811 1.69e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MAPGIKHE_01812 3.28e-66 - - - S - - - Protein of unknown function (DUF3397)
MAPGIKHE_01813 1.6e-114 cah 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
MAPGIKHE_01814 9.51e-47 WQ51_05710 - - S - - - Mitochondrial biogenesis AIM24
MAPGIKHE_01815 1.64e-16 - - - S - - - Mitochondrial biogenesis AIM24
MAPGIKHE_01816 1.08e-287 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MAPGIKHE_01817 8.53e-104 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
MAPGIKHE_01818 2.97e-100 - - - S - - - reductase
MAPGIKHE_01819 1.93e-93 XK27_09615 - - C ko:K19784 - ko00000 reductase
MAPGIKHE_01820 3.56e-178 XK27_09615 - - C ko:K19784 - ko00000 reductase
MAPGIKHE_01821 1.45e-09 nirC_1 - - P - - - Formate nitrite transporter
MAPGIKHE_01822 4.08e-81 nirC_1 - - P - - - Formate nitrite transporter
MAPGIKHE_01823 4.71e-64 XK27_08585 - - S ko:K16926 - ko00000,ko00002,ko02000 Psort location CytoplasmicMembrane, score
MAPGIKHE_01824 6.93e-237 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
MAPGIKHE_01825 1.95e-218 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
MAPGIKHE_01826 9.35e-152 gluP 3.4.21.105 - O ko:K19225 - ko00000,ko01000,ko01002 membrane protein (homolog of Drosophila rhomboid)
MAPGIKHE_01827 4.01e-122 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MAPGIKHE_01828 2.22e-279 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MAPGIKHE_01829 6.92e-105 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MAPGIKHE_01830 2.54e-29 - - - S ko:K07025 - ko00000 glycolate biosynthetic process
MAPGIKHE_01831 5.33e-86 - - - S ko:K07025 - ko00000 phosphatase activity
MAPGIKHE_01832 4.03e-202 rrmA 2.1.1.187 - Q ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 methyltransferase
MAPGIKHE_01835 1.75e-113 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MAPGIKHE_01836 1.28e-85 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MAPGIKHE_01837 2.25e-49 yeeD - - O ko:K07112 - ko00000 sulfur carrier activity
MAPGIKHE_01838 2.09e-244 yeeE - - S ko:K07112 - ko00000 Sulphur transport
MAPGIKHE_01839 1.3e-145 XK27_10290 - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MAPGIKHE_01840 4.07e-72 ytpP - - CO - - - Thioredoxin
MAPGIKHE_01842 2.61e-260 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
MAPGIKHE_01843 4.76e-170 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MAPGIKHE_01844 1.6e-141 - - - S ko:K07052 - ko00000 CAAX amino terminal protease family protein
MAPGIKHE_01846 1.2e-85 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
MAPGIKHE_01847 4.3e-36 lanR - - K ko:K07729 - ko00000,ko03000 sequence-specific DNA binding
MAPGIKHE_01848 8.04e-283 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MAPGIKHE_01849 5.86e-227 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
MAPGIKHE_01850 7.17e-17 - - - U ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
MAPGIKHE_01851 7.93e-94 comGF - - U ko:K02248 - ko00000,ko00002,ko02044 Competence protein ComGF
MAPGIKHE_01852 1.28e-21 - - - NU - - - Type II secretory pathway pseudopilin
MAPGIKHE_01853 1.03e-75 cglD - - NU ko:K02246 - ko00000,ko00002,ko02044 Competence protein
MAPGIKHE_01854 2.23e-62 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
MAPGIKHE_01855 1.16e-183 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
MAPGIKHE_01856 1.57e-142 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MAPGIKHE_01857 0.0 - - - L ko:K07484 - ko00000 Transposase IS66 family
MAPGIKHE_01858 1.93e-29 - - - S - - - Transposase C of IS166 homeodomain
MAPGIKHE_01859 7.19e-83 XK27_01125 - - L ko:K07484 - ko00000 COG3436 Transposase and inactivated derivatives
MAPGIKHE_01860 6.69e-27 - - - - - - - -
MAPGIKHE_01861 2.61e-58 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MAPGIKHE_01862 1.13e-90 - - - S - - - cog cog4699
MAPGIKHE_01863 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MAPGIKHE_01864 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MAPGIKHE_01865 0.0 pbp1B 2.4.1.129 GT51 M ko:K03693,ko:K12551 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
MAPGIKHE_01866 1.43e-303 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MAPGIKHE_01867 2.67e-250 ilvC 1.1.1.86 - H ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MAPGIKHE_01868 2.89e-100 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
MAPGIKHE_01869 0.0 ilvB 2.2.1.6 - EH ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
MAPGIKHE_01870 2.5e-10 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
MAPGIKHE_01871 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
MAPGIKHE_01872 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
MAPGIKHE_01873 7.64e-76 asp - - S - - - cog cog1302
MAPGIKHE_01874 1.78e-284 norN - - V - - - Mate efflux family protein
MAPGIKHE_01875 0.0 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
MAPGIKHE_01876 2.58e-75 adh 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
MAPGIKHE_01877 2.35e-40 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 hydroxyacid-oxoacid transhydrogenase activity
MAPGIKHE_01878 1.65e-85 adh 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
MAPGIKHE_01879 5.93e-135 adh 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
MAPGIKHE_01880 2.28e-84 - 1.1.1.1, 1.2.1.10, 1.2.1.87 - C ko:K04072,ko:K13922 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Dehydrogenase
MAPGIKHE_01881 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
MAPGIKHE_01882 9.09e-147 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
MAPGIKHE_01883 4.11e-46 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
MAPGIKHE_01884 1.04e-14 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
MAPGIKHE_01885 5.8e-71 treB 2.7.1.201 - G ko:K02817,ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS System
MAPGIKHE_01886 1.54e-28 treR - - K ko:K03486,ko:K03710 - ko00000,ko03000 DNA-binding transcription factor activity
MAPGIKHE_01887 4.4e-112 treR - - K ko:K03486 - ko00000,ko03000 trehalose operon
MAPGIKHE_01888 2.27e-122 ywlG - - S - - - Belongs to the UPF0340 family
MAPGIKHE_01890 7.69e-18 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
MAPGIKHE_01891 1.51e-94 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
MAPGIKHE_01892 2.09e-250 - - - L - - - Belongs to the 'phage' integrase family
MAPGIKHE_01893 2.16e-39 - - - S - - - Psort location Cytoplasmic, score 8.87
MAPGIKHE_01894 7.28e-42 - - - S - - - Helix-turn-helix domain
MAPGIKHE_01895 4.17e-55 - - - K - - - Sigma-70, region 4
MAPGIKHE_01896 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 E1-E2 ATPase
MAPGIKHE_01897 6.67e-46 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MAPGIKHE_01898 9.16e-24 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MAPGIKHE_01899 6.69e-27 - - - - - - - -
MAPGIKHE_01900 7.19e-83 XK27_01125 - - L ko:K07484 - ko00000 COG3436 Transposase and inactivated derivatives
MAPGIKHE_01901 1.93e-29 - - - S - - - Transposase C of IS166 homeodomain
MAPGIKHE_01902 0.0 - - - L ko:K07484 - ko00000 Transposase IS66 family
MAPGIKHE_01903 7.96e-62 - - - K ko:K21903 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
MAPGIKHE_01904 7.83e-198 - - - L - - - Integrase core domain protein
MAPGIKHE_01905 2.79e-59 - - - L ko:K07483 - ko00000 Transposase
MAPGIKHE_01906 2.34e-259 - - - EGP - - - Major Facilitator Superfamily
MAPGIKHE_01907 1.75e-41 spaC2 - - V ko:K20484 ko02020,ko02024,map02020,map02024 ko00000,ko00001 Lanthionine synthetase C family protein
MAPGIKHE_01908 1.53e-52 - - - L - - - PFAM transposase IS3 IS911 family protein
MAPGIKHE_01910 1.85e-283 B4168_4126 - - L ko:K07493 - ko00000 Transposase
MAPGIKHE_01911 1.78e-133 - - - L - - - Phage integrase family
MAPGIKHE_01912 3.39e-115 - - - - - - - -
MAPGIKHE_01913 2.84e-27 - - - - - - - -
MAPGIKHE_01915 2.35e-121 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
MAPGIKHE_01916 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 HsdM N-terminal domain
MAPGIKHE_01917 0.0 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
MAPGIKHE_01918 2.84e-46 - - - - - - - -
MAPGIKHE_01919 1.3e-285 B4168_4126 - - L ko:K07493 - ko00000 Transposase
MAPGIKHE_01920 2.62e-179 - - - L - - - DNA integration
MAPGIKHE_01921 1.21e-211 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 aldolase
MAPGIKHE_01923 6.92e-85 - 6.3.2.2 - H ko:K01919,ko:K06048 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 ergothioneine biosynthetic process
MAPGIKHE_01924 4.66e-125 - - - H - - - gamma-glutamylcysteine synthetase
MAPGIKHE_01925 6.93e-15 - - - H - - - gamma-glutamylcysteine synthetase
MAPGIKHE_01926 7.69e-18 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
MAPGIKHE_01927 1.51e-94 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
MAPGIKHE_01928 2.13e-83 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 ribosomal protein l17
MAPGIKHE_01929 5.37e-220 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MAPGIKHE_01930 1.57e-80 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MAPGIKHE_01931 4.42e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MAPGIKHE_01932 3.26e-22 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
MAPGIKHE_01933 6.91e-45 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MAPGIKHE_01934 1.06e-154 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MAPGIKHE_01935 9.03e-295 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MAPGIKHE_01936 4.03e-83 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
MAPGIKHE_01937 1.65e-31 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 ribosomal protein l30
MAPGIKHE_01938 5.75e-103 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MAPGIKHE_01939 5.03e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MAPGIKHE_01940 1.44e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MAPGIKHE_01941 1.54e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MAPGIKHE_01942 2.03e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MAPGIKHE_01943 5.86e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MAPGIKHE_01944 3.99e-64 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MAPGIKHE_01945 1.04e-78 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MAPGIKHE_01946 7.55e-53 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MAPGIKHE_01947 4.36e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
MAPGIKHE_01948 3.58e-93 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MAPGIKHE_01949 4.49e-151 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MAPGIKHE_01950 1.21e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MAPGIKHE_01951 2.83e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MAPGIKHE_01952 7.19e-196 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MAPGIKHE_01953 6e-60 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MAPGIKHE_01954 2.49e-134 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
MAPGIKHE_01955 3.17e-142 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MAPGIKHE_01956 7.41e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
MAPGIKHE_01957 2.95e-239 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MAPGIKHE_01958 0.0 XK27_09800 - - I - - - Acyltransferase
MAPGIKHE_01959 2.43e-47 - - - S - - - MORN repeat protein
MAPGIKHE_01960 3.25e-106 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MAPGIKHE_01961 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MAPGIKHE_01962 2.62e-116 flaR - - F - - - topology modulation protein
MAPGIKHE_01963 2.62e-17 - - - K - - - Transcriptional activator, Rgg GadR MutR family
MAPGIKHE_01964 4.66e-165 Z012_04635 - - K - - - sequence-specific DNA binding
MAPGIKHE_01966 3.75e-278 - - - C ko:K06871 - ko00000 Radical SAM
MAPGIKHE_01967 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC transporter transmembrane region
MAPGIKHE_01968 1.71e-116 - - - K - - - sequence-specific DNA binding
MAPGIKHE_01969 1.8e-206 - - - L - - - Replication initiation factor
MAPGIKHE_01970 1.95e-26 - - - S - - - Domain of unknown function (DUF3173)
MAPGIKHE_01971 1.75e-277 - - - L - - - Belongs to the 'phage' integrase family
MAPGIKHE_01973 3.74e-303 rarA - - L ko:K07478 - ko00000 ATPase related to the helicase subunit of the Holliday junction resolvase
MAPGIKHE_01974 1.73e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
MAPGIKHE_01975 3.4e-59 yrzL - - S - - - Belongs to the UPF0297 family
MAPGIKHE_01976 8.4e-93 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MAPGIKHE_01977 2.7e-62 yrzB - - S - - - Belongs to the UPF0473 family
MAPGIKHE_01978 0.0 - - - S - - - the current gene model (or a revised gene model) may contain a frame shift
MAPGIKHE_01979 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
MAPGIKHE_01980 7.68e-20 - - - - - - - -
MAPGIKHE_01981 1.87e-118 - - - K - - - acetyltransferase
MAPGIKHE_01982 2.18e-150 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MAPGIKHE_01983 1.33e-186 XK27_08125 - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
MAPGIKHE_01984 1.03e-213 XK27_01785 - - S - - - cog cog1284
MAPGIKHE_01985 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
MAPGIKHE_01987 4.78e-308 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
MAPGIKHE_01988 5.56e-170 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
MAPGIKHE_01989 4.12e-43 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
MAPGIKHE_01990 4.33e-36 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
MAPGIKHE_01991 1.22e-26 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
MAPGIKHE_01992 4.55e-286 B4168_4126 - - L ko:K07493 - ko00000 Transposase
MAPGIKHE_01995 1.1e-105 yegS - - I - - - Diacylglycerol kinase
MAPGIKHE_01996 1.25e-125 - - - S - - - Hydrophobic domain protein
MAPGIKHE_01998 7.98e-45 ytgB - - S - - - Membrane
MAPGIKHE_01999 1.88e-131 - - - - - - - -
MAPGIKHE_02000 7.54e-285 B4168_4126 - - L ko:K07493 - ko00000 Transposase
MAPGIKHE_02001 7.53e-33 - - - S - - - Small integral membrane protein
MAPGIKHE_02002 1.44e-104 - - - S - - - Asp23 family, cell envelope-related function
MAPGIKHE_02003 6.77e-34 - - - K - - - CsbD-like
MAPGIKHE_02004 1.88e-124 XK27_06885 - - L - - - hydrolase
MAPGIKHE_02005 2.9e-18 XK27_06885 - - L - - - hydrolase
MAPGIKHE_02006 2.32e-64 XK27_06915 - - K ko:K10947 - ko00000,ko03000 transcriptional regulator, PadR family
MAPGIKHE_02007 1.91e-10 - - - S - - - Protein of unknown function (DUF1700)
MAPGIKHE_02008 3.31e-20 - - - S - - - Protein of unknown function (DUF1700)
MAPGIKHE_02009 3.02e-149 - - - S - - - Putative adhesin
MAPGIKHE_02010 4.15e-269 XK27_06930 - - V ko:K01421 - ko00000 domain protein
MAPGIKHE_02011 3.98e-124 XK27_06935 - - K - - - transcriptional regulator
MAPGIKHE_02012 2.2e-68 ypaA - - S ko:K08987 - ko00000 membrane
MAPGIKHE_02013 5.92e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MAPGIKHE_02014 3.05e-63 WQ51_01655 - - S - - - Biofilm formation stimulator VEG
MAPGIKHE_02015 1.29e-312 dnaC 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
MAPGIKHE_02016 1.24e-98 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
MAPGIKHE_02017 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
MAPGIKHE_02018 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MAPGIKHE_02019 2.21e-277 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MAPGIKHE_02020 0.0 - - - S - - - Bacterial membrane protein, YfhO
MAPGIKHE_02021 1.83e-121 isaA - - M - - - Immunodominant staphylococcal antigen A
MAPGIKHE_02022 5.36e-120 lytE - - M - - - LysM domain protein
MAPGIKHE_02023 4.25e-177 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MAPGIKHE_02024 2.6e-195 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MAPGIKHE_02025 5.46e-195 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MAPGIKHE_02026 7.67e-118 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MAPGIKHE_02027 3.6e-184 ymfM - - S ko:K15539 - ko00000 sequence-specific DNA binding
MAPGIKHE_02028 5.52e-302 ymfH - - S - - - Peptidase M16
MAPGIKHE_02029 6.88e-296 albE - - S - - - Peptidase M16
MAPGIKHE_02030 4.32e-68 yaaA - - S - - - S4 domain protein YaaA
MAPGIKHE_02031 4.52e-262 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MAPGIKHE_02032 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
MAPGIKHE_02033 1.17e-244 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
MAPGIKHE_02034 5.63e-195 XK27_10395 - - S - - - membrane
MAPGIKHE_02035 0.0 ykpA - - S - - - abc transporter atp-binding protein
MAPGIKHE_02036 0.0 XK27_10405 - - S - - - Bacterial membrane protein YfhO
MAPGIKHE_02040 3.66e-155 yveI - - S - - - Psort location CytoplasmicMembrane, score
MAPGIKHE_02041 2.08e-111 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MAPGIKHE_02042 3.83e-263 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
MAPGIKHE_02043 9.27e-172 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)