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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HILFDMDG_00001	1.3e-211	-	-	-	L	ko:K07448	-	ko00000,ko02048	restriction endonuclease
HILFDMDG_00002	3.06e-87	-	-	-	L	ko:K07448	-	ko00000,ko02048	restriction endonuclease
HILFDMDG_00003	7.81e-59	mrr2	-	-	L	ko:K07448	-	ko00000,ko02048	restriction endonuclease
HILFDMDG_00004	0.0	-	-	-	L	-	-	-	PLD-like domain
HILFDMDG_00006	1.5e-227	rihA	-	-	F	ko:K01250	-	ko00000,ko01000	Inosine-uridine preferring nucleoside hydrolase
HILFDMDG_00007	2.44e-227	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HILFDMDG_00008	3.63e-119	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
HILFDMDG_00009	2.95e-283	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
HILFDMDG_00010	6.42e-101	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HILFDMDG_00011	5.2e-146	-	-	-	T	ko:K10716	-	ko00000,ko02000	Ion transport 2 domain protein
HILFDMDG_00012	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
HILFDMDG_00013	1.49e-272	-	-	-	G	-	-	-	Transporter, major facilitator family protein
HILFDMDG_00014	2.88e-141	yvrI	-	-	K	ko:K03091,ko:K03093	-	ko00000,ko03021	sigma factor activity
HILFDMDG_00015	1.12e-83	yuxO	-	-	Q	-	-	-	Thioesterase superfamily
HILFDMDG_00016	6.96e-201	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HILFDMDG_00017	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HILFDMDG_00018	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
HILFDMDG_00019	9.89e-43	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain
HILFDMDG_00020	5.43e-185	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
HILFDMDG_00021	1.85e-302	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
HILFDMDG_00022	1.11e-299	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HILFDMDG_00023	4.52e-106	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
HILFDMDG_00024	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
HILFDMDG_00025	3.38e-76	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HILFDMDG_00026	1.29e-203	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
HILFDMDG_00027	3.34e-128	nreC	-	-	K	ko:K07696	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	PFAM regulatory protein LuxR
HILFDMDG_00028	1.18e-50	-	-	-	S	-	-	-	Cytochrome B5
HILFDMDG_00029	1.77e-197	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HILFDMDG_00030	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
HILFDMDG_00031	1.8e-190	-	-	-	O	-	-	-	Band 7 protein
HILFDMDG_00032	0.0	lytS	2.7.13.3	-	T	ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	LytS YhcK-type transmembrane receptor domain protein
HILFDMDG_00033	2.9e-169	lytT	-	-	K	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator receiver
HILFDMDG_00034	3.69e-87	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	LrgA family
HILFDMDG_00035	2.53e-160	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	LrgB-like family
HILFDMDG_00036	6.86e-229	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HILFDMDG_00037	3.11e-218	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
HILFDMDG_00038	3.71e-236	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding protein-like domain
HILFDMDG_00039	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HILFDMDG_00040	6.82e-119	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
HILFDMDG_00041	8.91e-248	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HILFDMDG_00042	1.13e-271	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
HILFDMDG_00043	5.83e-225	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
HILFDMDG_00044	1.72e-218	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
HILFDMDG_00045	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
HILFDMDG_00046	6.66e-115	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
HILFDMDG_00047	9.68e-159	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
HILFDMDG_00048	2.32e-206	-	-	-	EG	-	-	-	EamA-like transporter family
HILFDMDG_00049	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
HILFDMDG_00050	2.35e-151	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HILFDMDG_00051	1.87e-132	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
HILFDMDG_00052	6.82e-74	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HILFDMDG_00053	1.01e-109	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
HILFDMDG_00054	1.03e-283	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
HILFDMDG_00055	5.39e-92	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
HILFDMDG_00056	2.58e-85	esbA	-	-	S	-	-	-	Family of unknown function (DUF5322)
HILFDMDG_00057	1.41e-93	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HILFDMDG_00058	6.55e-221	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HILFDMDG_00059	7.52e-263	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
HILFDMDG_00060	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HILFDMDG_00061	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
HILFDMDG_00062	2.95e-207	-	-	-	S	-	-	-	EDD domain protein, DegV family
HILFDMDG_00063	7.18e-126	-	-	-	-	-	-	-	-
HILFDMDG_00064	1.24e-153	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HILFDMDG_00065	8.83e-173	gspA	-	-	M	-	-	-	family 8
HILFDMDG_00066	5.98e-206	-	-	-	S	-	-	-	Alpha beta hydrolase
HILFDMDG_00067	4.52e-123	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HILFDMDG_00068	1.19e-138	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
HILFDMDG_00069	2.76e-63	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
HILFDMDG_00070	1.19e-50	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
HILFDMDG_00071	1.12e-213	yvgN	-	-	C	-	-	-	Aldo keto reductase
HILFDMDG_00072	3.37e-57	-	-	-	K	-	-	-	Transcriptional regulator
HILFDMDG_00073	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HILFDMDG_00074	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HILFDMDG_00075	2.61e-204	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
HILFDMDG_00076	4.93e-123	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
HILFDMDG_00077	6.66e-113	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HILFDMDG_00078	3.04e-154	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
HILFDMDG_00079	9.19e-209	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
HILFDMDG_00080	5.83e-177	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HILFDMDG_00081	2.48e-161	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
HILFDMDG_00082	3.22e-213	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HILFDMDG_00083	2.64e-302	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HILFDMDG_00084	9.43e-56	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
HILFDMDG_00085	2.62e-300	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HILFDMDG_00086	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HILFDMDG_00087	1.04e-85	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HILFDMDG_00088	9.28e-89	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
HILFDMDG_00089	1.13e-186	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	biotin lipoate A B protein ligase
HILFDMDG_00090	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
HILFDMDG_00091	1.1e-188	yidA	-	-	S	-	-	-	hydrolase
HILFDMDG_00092	6.01e-101	-	-	-	-	-	-	-	-
HILFDMDG_00093	9.36e-229	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HILFDMDG_00094	3.17e-314	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HILFDMDG_00095	5.24e-191	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
HILFDMDG_00096	3.54e-165	-	-	-	U	ko:K02075	-	ko00000,ko00002,ko02000	ABC 3 transport family
HILFDMDG_00097	8.05e-157	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HILFDMDG_00098	2.02e-215	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HILFDMDG_00099	2.44e-206	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HILFDMDG_00100	2.74e-50	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
HILFDMDG_00101	6.45e-209	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HILFDMDG_00102	1.42e-126	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HILFDMDG_00103	3.73e-200	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
HILFDMDG_00104	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HILFDMDG_00105	1.52e-204	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
HILFDMDG_00107	1.69e-167	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
HILFDMDG_00108	3.66e-226	-	-	-	-	-	-	-	-
HILFDMDG_00109	3.92e-288	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
HILFDMDG_00110	2.53e-214	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HILFDMDG_00111	2.26e-242	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HILFDMDG_00112	5.96e-241	-	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	Belongs to the N(4) N(6)-methyltransferase family
HILFDMDG_00113	1.17e-105	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
HILFDMDG_00114	0.0	-	-	-	L	-	-	-	DNA helicase
HILFDMDG_00115	4.11e-256	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HILFDMDG_00116	2.47e-250	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HILFDMDG_00117	2.48e-49	-	-	-	L	-	-	-	Transposase, IS116 IS110 IS902 family
HILFDMDG_00119	0.0	gabT	2.6.1.19, 5.1.1.21	-	E	ko:K00823,ko:K20708	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HILFDMDG_00120	0.0	ctrA	-	-	E	ko:K03294	-	ko00000	amino acid
HILFDMDG_00121	1.91e-150	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HILFDMDG_00122	5.98e-55	-	1.3.5.4	-	S	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FMN binding
HILFDMDG_00123	5.93e-281	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	transporter
HILFDMDG_00124	5.14e-217	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HILFDMDG_00125	4.65e-195	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HILFDMDG_00126	2.44e-244	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HILFDMDG_00127	1.06e-139	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HILFDMDG_00128	2.05e-277	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
HILFDMDG_00129	4.59e-36	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HILFDMDG_00130	1.47e-28	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HILFDMDG_00131	5.99e-306	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HILFDMDG_00132	1.94e-227	-	-	-	-	-	-	-	-
HILFDMDG_00133	5.27e-169	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HILFDMDG_00134	5.57e-308	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
HILFDMDG_00135	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
HILFDMDG_00136	4.78e-135	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HILFDMDG_00137	5.52e-241	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
HILFDMDG_00138	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HILFDMDG_00139	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HILFDMDG_00140	1.9e-161	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HILFDMDG_00141	2.94e-46	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HILFDMDG_00142	4.3e-169	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
HILFDMDG_00143	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HILFDMDG_00144	3.15e-278	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HILFDMDG_00145	6.05e-108	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HILFDMDG_00146	4.28e-128	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HILFDMDG_00147	3.61e-219	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
HILFDMDG_00148	1.26e-232	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
HILFDMDG_00149	4.79e-161	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Belongs to the alpha-acetolactate decarboxylase family
HILFDMDG_00150	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
HILFDMDG_00151	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
HILFDMDG_00152	6.76e-227	ydbI	-	-	K	-	-	-	AI-2E family transporter
HILFDMDG_00153	2.33e-291	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
HILFDMDG_00154	8.72e-147	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HILFDMDG_00155	9.09e-149	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HILFDMDG_00156	1.96e-167	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HILFDMDG_00157	2.66e-218	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HILFDMDG_00158	5.01e-312	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HILFDMDG_00159	1.81e-221	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HILFDMDG_00160	5.06e-182	-	-	-	K	-	-	-	LysR substrate binding domain
HILFDMDG_00161	9.94e-71	-	-	-	S	-	-	-	branched-chain amino acid
HILFDMDG_00162	3.97e-185	-	-	-	E	-	-	-	AzlC protein
HILFDMDG_00163	7.53e-264	hpk31	-	-	T	-	-	-	Histidine kinase
HILFDMDG_00164	9.76e-161	vanR	-	-	K	-	-	-	response regulator
HILFDMDG_00165	9.9e-264	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HILFDMDG_00166	8.89e-218	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	sugar-binding domain protein
HILFDMDG_00167	3.27e-167	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
HILFDMDG_00168	2.45e-304	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	pyrimidine-nucleoside phosphorylase
HILFDMDG_00169	2.8e-299	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
HILFDMDG_00170	5.64e-153	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HILFDMDG_00171	6.04e-173	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
HILFDMDG_00172	6.1e-255	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HILFDMDG_00173	5.8e-43	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
HILFDMDG_00174	2.79e-197	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HILFDMDG_00175	2.79e-178	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
HILFDMDG_00176	1.3e-200	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HILFDMDG_00177	9.32e-165	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
HILFDMDG_00178	2.43e-207	-	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase
HILFDMDG_00179	2.03e-219	rihA	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
HILFDMDG_00180	3.98e-277	nupG	-	-	F	ko:K03317,ko:K11535,ko:K16323	-	ko00000,ko02000	Nucleoside transporter
HILFDMDG_00181	2.15e-286	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HILFDMDG_00182	8.05e-178	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HILFDMDG_00183	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HILFDMDG_00184	0.0	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HILFDMDG_00186	5.38e-144	-	-	-	M	-	-	-	Rib/alpha-like repeat
HILFDMDG_00187	7.53e-157	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HILFDMDG_00188	6.36e-277	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HILFDMDG_00189	2.31e-176	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HILFDMDG_00190	2.47e-101	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
HILFDMDG_00192	3.96e-178	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HILFDMDG_00193	0.0	yhaN	-	-	L	-	-	-	AAA domain
HILFDMDG_00194	1e-270	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
HILFDMDG_00195	1.4e-63	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
HILFDMDG_00196	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HILFDMDG_00197	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
HILFDMDG_00198	1.69e-191	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HILFDMDG_00199	7.01e-216	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HILFDMDG_00201	1.22e-53	-	-	-	-	-	-	-	-
HILFDMDG_00202	5.38e-60	-	-	-	-	-	-	-	-
HILFDMDG_00203	1.2e-263	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydropteroate synthase
HILFDMDG_00204	5.53e-132	folQ	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
HILFDMDG_00205	5.27e-281	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HILFDMDG_00206	1.17e-136	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
HILFDMDG_00207	2.63e-120	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
HILFDMDG_00208	1.43e-73	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HILFDMDG_00209	2.57e-90	-	-	-	-	-	-	-	-
HILFDMDG_00211	9.17e-59	-	-	-	-	-	-	-	-
HILFDMDG_00212	1.43e-151	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HILFDMDG_00213	4.38e-43	-	-	-	-	-	-	-	-
HILFDMDG_00214	1.63e-207	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HILFDMDG_00215	2.41e-236	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
HILFDMDG_00216	1.53e-146	-	-	-	-	-	-	-	-
HILFDMDG_00217	3.06e-150	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
HILFDMDG_00218	1.75e-221	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HILFDMDG_00219	4.4e-112	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
HILFDMDG_00220	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
HILFDMDG_00221	1.09e-190	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HILFDMDG_00222	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HILFDMDG_00223	2.07e-55	-	-	-	-	-	-	-	-
HILFDMDG_00224	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
HILFDMDG_00225	6.66e-281	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HILFDMDG_00226	1.62e-123	tag1	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
HILFDMDG_00227	0.0	-	-	-	EGP	-	-	-	Major Facilitator
HILFDMDG_00228	3.59e-111	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
HILFDMDG_00229	1.35e-300	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HILFDMDG_00230	8.28e-135	-	-	-	V	-	-	-	VanZ like family
HILFDMDG_00231	7.03e-33	-	-	-	-	-	-	-	-
HILFDMDG_00232	4.13e-110	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
HILFDMDG_00233	4.58e-103	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HILFDMDG_00234	0.0	umuC	-	-	L	ko:K03502	-	ko00000,ko03400	impB/mucB/samB family C-terminal domain
HILFDMDG_00235	4.63e-101	hsp	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HILFDMDG_00236	3.69e-196	yeaE	-	-	S	-	-	-	Aldo keto
HILFDMDG_00237	3.25e-309	-	1.3.1.1	-	C	ko:K17723	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
HILFDMDG_00238	6.91e-299	-	1.3.1.1	-	E	ko:K17722	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
HILFDMDG_00239	2.95e-192	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HILFDMDG_00240	1.1e-131	-	-	-	M	-	-	-	LysM domain protein
HILFDMDG_00241	0.0	-	-	-	EP	-	-	-	Psort location Cytoplasmic, score
HILFDMDG_00242	1.73e-151	-	-	-	M	-	-	-	LysM domain protein
HILFDMDG_00243	1.68e-199	-	-	-	O	-	-	-	Uncharacterized protein family (UPF0051)
HILFDMDG_00244	1.09e-141	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HILFDMDG_00245	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
HILFDMDG_00246	2.87e-306	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
HILFDMDG_00247	6.7e-239	isp	-	-	L	-	-	-	Transposase
HILFDMDG_00248	1.17e-22	isp	-	-	L	-	-	-	Transposase
HILFDMDG_00249	4.91e-241	ampC	-	-	V	-	-	-	Beta-lactamase
HILFDMDG_00250	3.83e-74	-	-	-	-	-	-	-	-
HILFDMDG_00251	0.0	-	-	-	M	-	-	-	domain protein
HILFDMDG_00252	2.27e-138	-	-	-	-	-	-	-	-
HILFDMDG_00254	3.35e-167	int2	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HILFDMDG_00255	9.56e-10	-	-	-	L	ko:K07474	-	ko00000	Terminase small subunit
HILFDMDG_00256	4.09e-30	-	-	-	K	ko:K07727	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
HILFDMDG_00257	9.17e-25	-	-	-	S	-	-	-	Helix-turn-helix domain
HILFDMDG_00258	2.9e-54	-	-	-	S	-	-	-	Phage regulatory protein Rha (Phage_pRha)
HILFDMDG_00263	2.23e-13	-	-	-	L	-	-	-	DnaD domain protein
HILFDMDG_00265	7.32e-91	-	-	-	-	-	-	-	-
HILFDMDG_00270	0.0	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HILFDMDG_00271	1.28e-75	-	-	-	-	-	-	-	-
HILFDMDG_00273	2.69e-114	-	-	-	-	-	-	-	-
HILFDMDG_00274	0.0	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
HILFDMDG_00275	1.27e-64	-	-	-	S	-	-	-	Cupredoxin-like domain
HILFDMDG_00276	1.6e-82	-	-	-	S	-	-	-	Cupredoxin-like domain
HILFDMDG_00277	9.98e-134	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
HILFDMDG_00278	1.69e-201	-	-	-	EG	-	-	-	EamA-like transporter family
HILFDMDG_00279	2.28e-220	arcC	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	Belongs to the carbamate kinase family
HILFDMDG_00280	9.21e-244	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HILFDMDG_00281	4.34e-198	-	-	-	KT	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	YcbB domain
HILFDMDG_00282	0.0	xylB	2.7.1.17, 2.7.1.53	-	G	ko:K00854,ko:K00880	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the FGGY kinase family
HILFDMDG_00283	0.0	xylA	5.3.1.5	-	G	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko01000	Belongs to the xylose isomerase family
HILFDMDG_00284	4.44e-17	yjeA	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	polysaccharide deacetylase
HILFDMDG_00285	8.42e-27	pgdA	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	polysaccharide deacetylase
HILFDMDG_00286	0.0	-	-	-	G	-	-	-	Right handed beta helix region
HILFDMDG_00287	0.0	-	-	-	G	ko:K03292	-	ko00000	MFS/sugar transport protein
HILFDMDG_00288	3.65e-222	rhaS2	-	-	K	-	-	-	Transcriptional regulator, AraC family
HILFDMDG_00289	0.0	xylT	-	-	EGP	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HILFDMDG_00291	8.67e-276	xylR	-	-	GK	-	-	-	ROK family
HILFDMDG_00292	2.49e-39	-	-	-	-	-	-	-	-
HILFDMDG_00293	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HILFDMDG_00294	5.5e-141	maa3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
HILFDMDG_00295	1.34e-200	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
HILFDMDG_00296	0.0	yclK	-	-	T	-	-	-	Histidine kinase
HILFDMDG_00297	2.31e-173	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
HILFDMDG_00299	1.31e-108	lytE	-	-	M	-	-	-	Lysin motif
HILFDMDG_00300	5.24e-189	-	-	-	S	-	-	-	Cof-like hydrolase
HILFDMDG_00301	1.23e-103	-	-	-	K	-	-	-	Transcriptional regulator
HILFDMDG_00302	0.0	oatA	-	-	I	-	-	-	Acyltransferase
HILFDMDG_00303	1.04e-69	-	-	-	-	-	-	-	-
HILFDMDG_00304	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HILFDMDG_00305	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HILFDMDG_00306	3.51e-161	ybbR	-	-	S	-	-	-	YbbR-like protein
HILFDMDG_00307	4.46e-193	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HILFDMDG_00308	0.0	fucP	-	-	G	ko:K02429	-	ko00000,ko02000	Major Facilitator Superfamily
HILFDMDG_00309	1.43e-87	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HILFDMDG_00310	3.08e-212	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HILFDMDG_00311	9.48e-170	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
HILFDMDG_00312	0.0	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HILFDMDG_00313	5.09e-153	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HILFDMDG_00314	2.25e-163	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HILFDMDG_00317	1.45e-10	-	-	-	S	-	-	-	Bacteriocin class II with double-glycine leader peptide
HILFDMDG_00319	7.05e-56	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HILFDMDG_00320	2.13e-158	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
HILFDMDG_00321	1.14e-310	-	-	-	T	-	-	-	GHKL domain
HILFDMDG_00322	1.38e-140	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HILFDMDG_00323	4.97e-174	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HILFDMDG_00324	6.01e-260	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HILFDMDG_00327	2.84e-109	flp	-	-	V	-	-	-	Beta-lactamase
HILFDMDG_00328	2.25e-70	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	decarboxylase
HILFDMDG_00329	1.59e-210	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	Oxidoreductase, aldo keto reductase family protein
HILFDMDG_00330	2.03e-108	-	-	-	C	-	-	-	Flavodoxin
HILFDMDG_00331	1.19e-200	lysR	-	-	K	-	-	-	Transcriptional regulator
HILFDMDG_00332	5.62e-224	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HILFDMDG_00333	2.2e-88	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
HILFDMDG_00334	1.87e-187	-	-	-	S	-	-	-	Alpha beta hydrolase
HILFDMDG_00335	1.63e-193	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
HILFDMDG_00336	1.32e-222	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HILFDMDG_00337	1.94e-290	aadAT	-	-	EK	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000	Aminotransferase, class I
HILFDMDG_00338	3.96e-212	ypuA	-	-	S	-	-	-	Protein of unknown function (DUF1002)
HILFDMDG_00339	9.44e-234	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase, type I
HILFDMDG_00340	2.6e-200	-	-	-	K	-	-	-	Transcriptional regulator
HILFDMDG_00341	7.46e-201	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
HILFDMDG_00342	1.61e-81	-	-	-	-	-	-	-	-
HILFDMDG_00343	4.89e-167	-	-	-	F	-	-	-	glutamine amidotransferase
HILFDMDG_00344	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
HILFDMDG_00345	4.1e-252	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
HILFDMDG_00346	1.79e-119	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
HILFDMDG_00347	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
HILFDMDG_00348	1.97e-143	-	-	-	GM	-	-	-	NAD dependent epimerase dehydratase family protein
HILFDMDG_00349	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
HILFDMDG_00350	3.09e-268	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HILFDMDG_00351	2.18e-289	-	-	-	-	-	-	-	-
HILFDMDG_00352	2.25e-100	-	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HILFDMDG_00353	1.3e-137	XK27_02070	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
HILFDMDG_00354	2.64e-67	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HILFDMDG_00355	2e-14	-	-	-	GM	-	-	-	NmrA-like family
HILFDMDG_00356	6.12e-11	-	-	-	S	ko:K02348	-	ko00000	Gnat family
HILFDMDG_00357	1.99e-50	-	-	-	S	ko:K02348	-	ko00000	Gnat family
HILFDMDG_00358	9.37e-52	-	-	-	S	-	-	-	Cytochrome B5
HILFDMDG_00359	8.47e-08	-	-	-	S	-	-	-	Cytochrome B5
HILFDMDG_00360	1.29e-53	-	-	-	S	-	-	-	Cytochrome B5
HILFDMDG_00361	1.45e-280	-	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
HILFDMDG_00363	4.68e-233	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HILFDMDG_00364	9.89e-315	-	-	-	E	ko:K03294	-	ko00000	amino acid
HILFDMDG_00365	4.74e-312	npp	-	-	S	-	-	-	type I phosphodiesterase nucleotide pyrophosphatase
HILFDMDG_00366	9.84e-132	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
HILFDMDG_00367	3.01e-28	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
HILFDMDG_00368	1.79e-42	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
HILFDMDG_00370	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HILFDMDG_00371	1.03e-72	-	-	-	-	-	-	-	-
HILFDMDG_00372	1.16e-112	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HILFDMDG_00373	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
HILFDMDG_00375	4.06e-287	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
HILFDMDG_00376	9.72e-225	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
HILFDMDG_00377	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HILFDMDG_00378	9.14e-205	-	-	-	EG	-	-	-	EamA-like transporter family
HILFDMDG_00379	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
HILFDMDG_00380	4.66e-312	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
HILFDMDG_00381	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HILFDMDG_00382	1.14e-148	-	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
HILFDMDG_00383	4.71e-162	pgm3	-	-	G	-	-	-	phosphoglycerate mutase
HILFDMDG_00384	5.29e-300	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HILFDMDG_00385	1.34e-47	-	-	-	S	-	-	-	Transglycosylase associated protein
HILFDMDG_00386	6.08e-13	-	-	-	S	-	-	-	CsbD-like
HILFDMDG_00387	7.72e-231	-	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HILFDMDG_00388	0.0	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
HILFDMDG_00389	2.14e-123	-	-	-	K	-	-	-	Transcriptional regulator (TetR family)
HILFDMDG_00390	2.91e-51	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain protein
HILFDMDG_00391	1.56e-191	-	-	-	-	-	-	-	-
HILFDMDG_00392	4.56e-34	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
HILFDMDG_00393	1.27e-108	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
HILFDMDG_00394	9.66e-133	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
HILFDMDG_00395	5.1e-97	-	-	-	F	-	-	-	Nudix hydrolase
HILFDMDG_00396	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
HILFDMDG_00397	1.3e-300	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
HILFDMDG_00398	4.14e-295	-	-	-	-	-	-	-	-
HILFDMDG_00399	2.08e-267	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HILFDMDG_00400	1.04e-181	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HILFDMDG_00401	2.49e-187	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HILFDMDG_00402	5.08e-262	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HILFDMDG_00403	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HILFDMDG_00404	1.5e-226	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HILFDMDG_00405	0.0	atp2C1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HILFDMDG_00406	9.44e-109	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
HILFDMDG_00407	5.28e-316	yagE	-	-	E	-	-	-	amino acid
HILFDMDG_00408	1.24e-147	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant
HILFDMDG_00409	4.85e-233	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
HILFDMDG_00410	1.57e-232	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
HILFDMDG_00411	2.48e-174	-	-	-	IQ	-	-	-	KR domain
HILFDMDG_00412	0.0	-	-	-	D	-	-	-	Domain of Unknown Function (DUF1542)
HILFDMDG_00413	1.21e-212	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
HILFDMDG_00414	0.0	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HILFDMDG_00415	1e-47	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HILFDMDG_00416	1.83e-299	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
HILFDMDG_00417	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HILFDMDG_00418	2.63e-08	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
HILFDMDG_00419	1.61e-81	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HILFDMDG_00420	7.62e-270	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HILFDMDG_00421	1.3e-82	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
HILFDMDG_00422	0.0	-	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
HILFDMDG_00423	1.46e-304	codA	3.5.4.1	-	F	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000	cytosine deaminase
HILFDMDG_00424	1.14e-185	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
HILFDMDG_00425	3.84e-145	-	-	-	S	-	-	-	(CBS) domain
HILFDMDG_00426	5.62e-132	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HILFDMDG_00427	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HILFDMDG_00428	1.01e-52	yabO	-	-	J	-	-	-	S4 domain protein
HILFDMDG_00429	1.23e-75	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
HILFDMDG_00430	5.75e-103	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
HILFDMDG_00431	0.0	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HILFDMDG_00432	3.68e-125	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
HILFDMDG_00433	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HILFDMDG_00434	3.1e-216	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HILFDMDG_00435	2.53e-240	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HILFDMDG_00436	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HILFDMDG_00437	5.01e-68	entB	-	-	Q	-	-	-	Isochorismatase family
HILFDMDG_00438	5.39e-64	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
HILFDMDG_00439	6.78e-81	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
HILFDMDG_00440	2e-70	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HILFDMDG_00441	4.09e-196	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
HILFDMDG_00442	3.16e-313	-	-	-	E	-	-	-	Peptidase family M20/M25/M40
HILFDMDG_00443	2.06e-278	-	-	-	G	-	-	-	Transporter, major facilitator family protein
HILFDMDG_00444	1.3e-262	menC	4.2.1.113	-	H	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
HILFDMDG_00445	2.64e-286	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
HILFDMDG_00446	1.03e-127	-	-	-	S	-	-	-	AmiS/UreI family transporter
HILFDMDG_00447	3.71e-64	ureA	3.5.1.5	-	E	ko:K01430	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Urease, gamma subunit
HILFDMDG_00448	6.94e-92	ureB	3.5.1.5	-	E	ko:K01429	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Urease beta subunit
HILFDMDG_00449	0.0	ureC	3.5.1.5	-	E	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	ko00000,ko00001,ko01000	Amidohydrolase family
HILFDMDG_00450	3.08e-102	ureE	-	-	O	ko:K03187	-	ko00000	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
HILFDMDG_00451	1.45e-170	ureF	-	-	O	ko:K03188	-	ko00000	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
HILFDMDG_00452	1.4e-145	ureG	-	-	KO	ko:K03189	-	ko00000	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HILFDMDG_00453	4.23e-212	ureD	-	-	O	ko:K03190	-	ko00000	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
HILFDMDG_00454	1.35e-237	cbiM	-	-	P	ko:K02007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PDGLE domain
HILFDMDG_00455	2.86e-184	-	-	-	P	ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HILFDMDG_00456	3.28e-174	-	-	-	P	ko:K02006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HILFDMDG_00457	2.14e-172	-	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C-terminal domain protein
HILFDMDG_00458	4.9e-205	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HILFDMDG_00459	9.65e-196	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HILFDMDG_00460	2.58e-197	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
HILFDMDG_00461	3.14e-177	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HILFDMDG_00462	6.09e-162	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
HILFDMDG_00463	1.32e-277	-	-	-	EGP	-	-	-	MFS transporter, metabolite H symporter (MHS) family protein
HILFDMDG_00464	1.37e-152	-	-	-	-	-	-	-	-
HILFDMDG_00466	2.67e-266	-	-	-	M	-	-	-	Glycosyl transferase
HILFDMDG_00467	2.04e-209	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
HILFDMDG_00468	7.72e-179	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
HILFDMDG_00469	0.0	mycA	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
HILFDMDG_00470	1.59e-303	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
HILFDMDG_00471	2.8e-152	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
HILFDMDG_00472	3.1e-113	-	-	-	Q	-	-	-	Methyltransferase
HILFDMDG_00473	2.3e-294	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HILFDMDG_00474	1.14e-229	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
HILFDMDG_00475	3.61e-214	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HILFDMDG_00476	1.95e-110	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HILFDMDG_00477	1.1e-218	-	-	-	S	-	-	-	Conserved hypothetical protein 698
HILFDMDG_00478	1.6e-211	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HILFDMDG_00479	8.91e-141	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HILFDMDG_00480	4.55e-158	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
HILFDMDG_00481	1.05e-146	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
HILFDMDG_00482	2.16e-19	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
HILFDMDG_00483	0.0	arcD	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
HILFDMDG_00484	0.0	arcT	-	-	E	-	-	-	Dipeptidase
HILFDMDG_00485	4.44e-272	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
HILFDMDG_00486	0.0	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Sucrose glucosyltransferase
HILFDMDG_00487	1.87e-176	-	-	-	V	-	-	-	Beta-lactamase enzyme family
HILFDMDG_00488	3.34e-286	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HILFDMDG_00489	6.26e-96	-	-	-	-	-	-	-	-
HILFDMDG_00490	5.94e-303	arcA	3.5.3.6	-	E	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	ko00000,ko00001,ko01000	Arginine
HILFDMDG_00491	6.17e-104	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HILFDMDG_00492	0.0	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
HILFDMDG_00493	4.84e-298	potE	-	-	U	ko:K03756,ko:K03758	-	ko00000,ko02000	Amino acid permease
HILFDMDG_00495	8.08e-172	-	-	-	S	ko:K07009	-	ko00000	CobB/CobQ-like glutamine amidotransferase domain
HILFDMDG_00496	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Mur ligase, middle domain
HILFDMDG_00497	6.8e-140	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
HILFDMDG_00498	1.73e-248	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HILFDMDG_00499	1.59e-209	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HILFDMDG_00500	7.66e-251	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HILFDMDG_00501	2.58e-293	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HILFDMDG_00502	6.68e-150	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HILFDMDG_00503	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HILFDMDG_00504	4.52e-244	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
HILFDMDG_00505	1.35e-165	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
HILFDMDG_00506	1.62e-293	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
HILFDMDG_00507	3.8e-161	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HILFDMDG_00508	1.26e-29	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HILFDMDG_00509	1.07e-95	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HILFDMDG_00510	6.84e-121	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HILFDMDG_00511	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HILFDMDG_00512	1.3e-212	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HILFDMDG_00513	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HILFDMDG_00514	8.95e-90	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HILFDMDG_00515	5.05e-45	ywzB	-	-	S	-	-	-	Protein of unknown function (DUF1146)
HILFDMDG_00516	1.81e-309	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HILFDMDG_00517	2.57e-227	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
HILFDMDG_00518	4.61e-44	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
HILFDMDG_00519	9.49e-282	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
HILFDMDG_00520	1.21e-63	gcsH2	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	glycine cleavage
HILFDMDG_00521	2.21e-275	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HILFDMDG_00522	1.23e-189	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HILFDMDG_00523	0.0	araP	-	-	U	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HILFDMDG_00524	0.0	araB	2.7.1.16	-	G	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	carbohydrate kinase FGGY
HILFDMDG_00525	5.47e-178	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
HILFDMDG_00526	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
HILFDMDG_00527	3.33e-121	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
HILFDMDG_00528	2.32e-198	yvgN	-	-	S	-	-	-	Aldo keto reductase
HILFDMDG_00529	3.44e-261	araR	-	-	K	ko:K02103	-	ko00000,ko03000	Transcriptional regulator
HILFDMDG_00530	1.95e-109	uspA	-	-	T	-	-	-	universal stress protein
HILFDMDG_00531	4.53e-66	isp	-	-	L	-	-	-	Transposase
HILFDMDG_00532	6.33e-96	-	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Asp/Glu/Hydantoin racemase
HILFDMDG_00533	4.43e-43	-	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Asp/Glu/Hydantoin racemase
HILFDMDG_00534	1.22e-144	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
HILFDMDG_00535	3.96e-145	fnr	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
HILFDMDG_00536	1.09e-122	dpsB	-	-	P	-	-	-	Belongs to the Dps family
HILFDMDG_00537	2.25e-45	-	-	-	C	-	-	-	Heavy-metal-associated domain
HILFDMDG_00538	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	E1-E2 ATPase
HILFDMDG_00539	7.15e-133	-	-	-	-	-	-	-	-
HILFDMDG_00540	8.28e-78	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain protein
HILFDMDG_00541	3.84e-247	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	cog cog0286
HILFDMDG_00542	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
HILFDMDG_00543	1.46e-35	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HILFDMDG_00544	5.74e-94	-	-	-	L	-	-	-	ATPase involved in DNA repair
HILFDMDG_00546	2.7e-37	-	-	-	-	-	-	-	-
HILFDMDG_00548	1.22e-29	-	-	-	-	-	-	-	-
HILFDMDG_00549	2.17e-54	-	-	-	-	-	-	-	-
HILFDMDG_00550	5.38e-272	-	-	-	L	-	-	-	Protein of unknown function (DUF2800)
HILFDMDG_00551	5.47e-128	-	-	-	S	-	-	-	Protein of unknown function (DUF2815)
HILFDMDG_00552	0.0	-	2.7.7.7	-	L	ko:K02334	-	ko00000,ko01000	DNA polymerase
HILFDMDG_00553	1.02e-89	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HILFDMDG_00554	0.0	-	-	-	S	ko:K06919	-	ko00000	Phage plasmid primase, P4
HILFDMDG_00555	1.77e-61	-	-	-	S	-	-	-	VRR_NUC
HILFDMDG_00556	0.0	-	-	-	L	-	-	-	SNF2 family N-terminal domain
HILFDMDG_00557	4.85e-102	-	-	-	-	-	-	-	-
HILFDMDG_00558	2.31e-128	-	-	-	-	-	-	-	-
HILFDMDG_00559	4.17e-302	-	-	-	KL	-	-	-	DNA methylase
HILFDMDG_00560	7.24e-147	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HILFDMDG_00561	9.81e-41	-	-	-	S	-	-	-	Domain of unknown function (DUF5049)
HILFDMDG_00562	0.0	-	-	-	S	-	-	-	overlaps another CDS with the same product name
HILFDMDG_00563	4.04e-302	-	-	-	S	-	-	-	Phage portal protein
HILFDMDG_00564	8.37e-134	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
HILFDMDG_00565	8.21e-253	-	-	-	S	-	-	-	Phage capsid family
HILFDMDG_00566	2.85e-53	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HILFDMDG_00567	1.44e-73	-	-	-	S	-	-	-	Phage head-tail joining protein
HILFDMDG_00568	3.71e-72	-	-	-	S	-	-	-	Bacteriophage holin family
HILFDMDG_00569	6.53e-26	-	-	-	-	-	-	-	-
HILFDMDG_00570	1.59e-280	-	-	-	L	-	-	-	Recombinase zinc beta ribbon domain
HILFDMDG_00571	0.0	-	-	-	L	-	-	-	Recombinase
HILFDMDG_00572	1.4e-136	pncA	-	-	Q	-	-	-	Isochorismatase family
HILFDMDG_00573	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HILFDMDG_00574	1.74e-170	-	-	-	F	-	-	-	NUDIX domain
HILFDMDG_00575	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HILFDMDG_00576	1.64e-237	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
HILFDMDG_00577	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HILFDMDG_00578	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HILFDMDG_00579	1.36e-66	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HILFDMDG_00580	1.11e-260	camS	-	-	S	-	-	-	sex pheromone
HILFDMDG_00581	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HILFDMDG_00582	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
HILFDMDG_00583	8.91e-270	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HILFDMDG_00584	2.36e-131	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HILFDMDG_00585	3.07e-149	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
HILFDMDG_00586	4.46e-180	budC	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	reductase
HILFDMDG_00587	3.94e-85	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
HILFDMDG_00588	9.25e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HILFDMDG_00589	4.31e-182	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HILFDMDG_00590	1.67e-180	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HILFDMDG_00591	4.31e-198	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HILFDMDG_00592	2.47e-186	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HILFDMDG_00593	8.08e-83	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HILFDMDG_00594	2.19e-220	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HILFDMDG_00595	1.62e-83	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HILFDMDG_00596	5.37e-76	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HILFDMDG_00597	5.79e-21	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
HILFDMDG_00598	2.41e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HILFDMDG_00599	4.52e-161	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HILFDMDG_00600	1.66e-305	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HILFDMDG_00601	6.05e-93	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HILFDMDG_00602	5.94e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
HILFDMDG_00603	5.95e-112	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HILFDMDG_00604	5.03e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HILFDMDG_00605	2.6e-124	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HILFDMDG_00606	1.54e-87	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HILFDMDG_00607	7.42e-125	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HILFDMDG_00608	5.22e-65	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HILFDMDG_00609	3.62e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HILFDMDG_00610	1.1e-55	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HILFDMDG_00611	5.49e-38	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
HILFDMDG_00612	1.96e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HILFDMDG_00613	9.81e-157	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HILFDMDG_00614	4.36e-70	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HILFDMDG_00615	5.72e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HILFDMDG_00616	1.64e-203	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HILFDMDG_00617	3.61e-61	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HILFDMDG_00618	6.64e-139	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
HILFDMDG_00619	5.45e-153	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HILFDMDG_00620	1.28e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
HILFDMDG_00621	1.07e-40	-	-	-	L	-	-	-	Transposase
HILFDMDG_00622	5.98e-208	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HILFDMDG_00623	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HILFDMDG_00624	2.06e-108	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HILFDMDG_00625	2.51e-94	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HILFDMDG_00626	2.29e-152	comC	3.4.23.43	-	NOU	ko:K02236,ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	Type II secretory pathway prepilin signal peptidase PulO and related peptidases
HILFDMDG_00627	3.69e-260	-	-	-	-	-	-	-	-
HILFDMDG_00628	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HILFDMDG_00629	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HILFDMDG_00630	2.09e-143	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HILFDMDG_00631	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HILFDMDG_00632	2.81e-101	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
HILFDMDG_00633	1.8e-249	adhP	1.1.1.1	-	C	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HILFDMDG_00634	1.62e-229	-	-	-	S	ko:K06889	-	ko00000	Hydrolases of the alpha beta superfamily
HILFDMDG_00640	6.4e-149	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
HILFDMDG_00641	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
HILFDMDG_00643	2.79e-153	-	-	-	I	-	-	-	phosphatase
HILFDMDG_00644	3.68e-107	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HILFDMDG_00645	5.6e-171	-	-	-	S	-	-	-	Putative threonine/serine exporter
HILFDMDG_00646	2.17e-43	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
HILFDMDG_00647	7.76e-160	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
HILFDMDG_00648	8.16e-212	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
HILFDMDG_00649	7.33e-152	-	-	-	S	-	-	-	membrane
HILFDMDG_00650	2.34e-142	-	-	-	S	-	-	-	VIT family
HILFDMDG_00651	4.83e-108	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
HILFDMDG_00652	1.97e-173	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HILFDMDG_00653	5.46e-195	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HILFDMDG_00654	2.49e-141	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HILFDMDG_00655	1.04e-140	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HILFDMDG_00656	3.54e-276	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HILFDMDG_00657	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HILFDMDG_00658	9.52e-74	-	-	-	-	-	-	-	-
HILFDMDG_00659	3.21e-99	-	-	-	K	-	-	-	MerR HTH family regulatory protein
HILFDMDG_00660	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HILFDMDG_00661	2.43e-156	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
HILFDMDG_00662	7.56e-209	yjbO	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HILFDMDG_00664	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HILFDMDG_00665	4.41e-131	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
HILFDMDG_00666	4.54e-240	-	-	-	I	-	-	-	Alpha beta
HILFDMDG_00667	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
HILFDMDG_00668	5.46e-152	-	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
HILFDMDG_00669	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
HILFDMDG_00670	4.66e-201	-	-	-	K	-	-	-	LysR family
HILFDMDG_00671	7.24e-143	-	-	-	I	-	-	-	Alpha/beta hydrolase family
HILFDMDG_00672	5.47e-194	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HILFDMDG_00673	0.0	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
HILFDMDG_00674	1.56e-202	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
HILFDMDG_00675	4.97e-54	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
HILFDMDG_00676	1.14e-188	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HILFDMDG_00677	9.44e-223	mae	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme, NAD binding domain
HILFDMDG_00678	8.74e-158	citR	-	-	K	-	-	-	sugar-binding domain protein
HILFDMDG_00679	6.12e-216	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HILFDMDG_00680	6.01e-166	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HILFDMDG_00681	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HILFDMDG_00682	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HILFDMDG_00683	0.0	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
HILFDMDG_00684	5.46e-207	mleR	-	-	K	-	-	-	LysR family
HILFDMDG_00685	4.76e-143	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HILFDMDG_00686	3.86e-263	adh	1.1.1.1	-	C	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding alcohol dehydrogenase family protein
HILFDMDG_00687	0.0	-	-	-	L	-	-	-	PFAM plasmid pRiA4b ORF-3 family protein
HILFDMDG_00688	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
HILFDMDG_00691	6.02e-31	-	-	-	-	-	-	-	-
HILFDMDG_00692	4.47e-256	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HILFDMDG_00693	2.19e-124	-	-	-	L	-	-	-	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HILFDMDG_00694	5.03e-67	-	-	-	-	-	-	-	-
HILFDMDG_00695	0.0	-	-	-	S	-	-	-	SEC-C Motif Domain Protein
HILFDMDG_00696	1.09e-144	-	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
HILFDMDG_00697	3.79e-101	-	-	-	-	-	-	-	-
HILFDMDG_00698	9.38e-229	-	-	-	-	-	-	-	-
HILFDMDG_00699	4.14e-233	fecB	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
HILFDMDG_00700	1.14e-178	fecE	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HILFDMDG_00701	2.63e-168	fecD	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HILFDMDG_00702	1.72e-99	-	-	-	S	-	-	-	Flavodoxin
HILFDMDG_00703	2.29e-84	moaE	2.8.1.12	-	H	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	MoaE protein
HILFDMDG_00704	9.9e-49	moaD	-	-	H	ko:K03636	ko04122,map04122	ko00000,ko00001	ThiS family
HILFDMDG_00705	1.29e-279	narK	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	Transporter, major facilitator family protein
HILFDMDG_00706	4.74e-213	-	-	-	H	-	-	-	geranyltranstransferase activity
HILFDMDG_00707	7.77e-234	-	-	-	-	-	-	-	-
HILFDMDG_00708	1.79e-25	-	-	-	-	-	-	-	-
HILFDMDG_00709	2.22e-151	nreC	-	-	K	ko:K07696	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	PFAM regulatory protein LuxR
HILFDMDG_00710	5.31e-242	nreB	2.7.13.3	-	F	ko:K07683	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Sensor histidine kinase
HILFDMDG_00711	1.56e-60	-	-	-	-	-	-	-	-
HILFDMDG_00712	2.88e-136	mobA	2.7.7.77	-	H	ko:K03752	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HILFDMDG_00713	7.94e-109	mobB	-	-	H	ko:K03753	-	ko00000	molybdopterin-guanine dinucleotide biosynthesis protein
HILFDMDG_00714	2.1e-289	moeA	2.10.1.1	-	H	ko:K03750	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	MoeA N-terminal region (domain I and II)
HILFDMDG_00715	6.2e-103	moaB	2.7.7.75	-	H	ko:K03638	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	May be involved in the biosynthesis of molybdopterin
HILFDMDG_00716	1.47e-242	moeB	2.7.7.80	-	H	ko:K21029	ko04122,map04122	ko00000,ko00001,ko01000	ThiF family
HILFDMDG_00717	0.0	narZ	1.7.5.1	-	C	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HILFDMDG_00718	0.0	narH	1.7.5.1	-	C	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
HILFDMDG_00719	5.76e-128	narJ	-	-	C	ko:K00373	ko02020,map02020	ko00000,ko00001	nitrate reductase molybdenum cofactor assembly chaperone
HILFDMDG_00720	6.65e-168	narI	1.7.5.1	-	C	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase
HILFDMDG_00721	7.34e-194	-	-	-	EG	-	-	-	EamA-like transporter family
HILFDMDG_00722	1.63e-152	-	-	-	L	-	-	-	Integrase
HILFDMDG_00723	1.03e-203	rssA	-	-	S	-	-	-	Phospholipase, patatin family
HILFDMDG_00724	4.26e-128	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	Levansucrase/Invertase
HILFDMDG_00725	3.2e-242	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HILFDMDG_00726	2.69e-181	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	Levansucrase/Invertase
HILFDMDG_00727	1.39e-257	xerS	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HILFDMDG_00729	1.97e-74	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HILFDMDG_00730	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
HILFDMDG_00731	5.91e-184	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HILFDMDG_00732	3.73e-121	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
HILFDMDG_00733	1.62e-169	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
HILFDMDG_00737	3.49e-270	int2	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HILFDMDG_00738	4.85e-25	-	-	-	-	-	-	-	-
HILFDMDG_00739	3.24e-35	-	-	-	S	-	-	-	Bacterial PH domain
HILFDMDG_00740	1.34e-80	-	-	-	K	-	-	-	Peptidase S24-like
HILFDMDG_00741	6.25e-19	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HILFDMDG_00742	5e-50	-	-	-	-	-	-	-	-
HILFDMDG_00745	2.97e-41	-	-	-	-	-	-	-	-
HILFDMDG_00747	5.84e-105	-	-	-	S	-	-	-	Siphovirus Gp157
HILFDMDG_00748	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
HILFDMDG_00749	1.5e-181	-	-	-	L	-	-	-	AAA domain
HILFDMDG_00750	4.71e-119	-	-	-	-	-	-	-	-
HILFDMDG_00751	5.66e-186	-	-	-	S	-	-	-	Bifunctional DNA primase/polymerase, N-terminal
HILFDMDG_00752	1.9e-295	-	-	-	S	ko:K06919	-	ko00000	Virulence-associated protein E
HILFDMDG_00754	1.5e-77	-	-	-	S	-	-	-	VRR_NUC
HILFDMDG_00759	1.18e-50	-	-	-	-	-	-	-	-
HILFDMDG_00762	5.95e-106	-	-	-	S	-	-	-	Phage transcriptional regulator, ArpU family
HILFDMDG_00763	5.08e-19	-	-	-	S	-	-	-	Super-infection exclusion protein B
HILFDMDG_00764	8.89e-86	-	-	-	L	ko:K07474	-	ko00000	Terminase small subunit
HILFDMDG_00765	1.75e-276	yqaT	-	-	S	ko:K06909	-	ko00000	Phage terminase, large subunit
HILFDMDG_00766	4.27e-259	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
HILFDMDG_00767	2.42e-175	-	-	-	S	-	-	-	Phage Mu protein F like protein
HILFDMDG_00769	3.11e-83	-	-	-	S	-	-	-	aminoacyl-tRNA ligase activity
HILFDMDG_00770	6.99e-148	-	-	-	-	-	-	-	-
HILFDMDG_00771	6.67e-61	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HILFDMDG_00773	2.09e-57	-	-	-	S	-	-	-	exonuclease activity
HILFDMDG_00774	5.12e-56	-	-	-	-	-	-	-	-
HILFDMDG_00775	1.1e-109	-	-	-	S	-	-	-	Phage major tail protein 2
HILFDMDG_00776	2.04e-59	-	-	-	S	-	-	-	Pfam:Phage_TAC_12
HILFDMDG_00778	1.67e-222	-	-	-	S	-	-	-	peptidoglycan catabolic process
HILFDMDG_00780	6.48e-249	-	-	-	S	-	-	-	peptidoglycan catabolic process
HILFDMDG_00783	2.78e-98	-	-	-	S	-	-	-	Bacteriophage holin family
HILFDMDG_00784	8.33e-119	-	-	-	S	-	-	-	N-acetylmuramoyl-L-alanine amidase activity
HILFDMDG_00791	0.0	-	-	-	L	-	-	-	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HILFDMDG_00792	6.39e-73	-	-	-	-	-	-	-	-
HILFDMDG_00793	1.76e-147	frnE	5.3.4.1	-	Q	ko:K01829	-	ko00000,ko01000	DSBA-like thioredoxin domain
HILFDMDG_00794	4.23e-213	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HILFDMDG_00795	1.98e-09	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HILFDMDG_00796	1.54e-05	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HILFDMDG_00797	8.29e-14	-	-	-	S	-	-	-	Phage derived protein Gp49-like (DUF891)
HILFDMDG_00798	6.96e-57	int2	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HILFDMDG_00800	4.77e-65	yrvD	-	-	S	-	-	-	Pfam:DUF1049
HILFDMDG_00801	2.32e-194	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HILFDMDG_00802	1.38e-117	ntd	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside
HILFDMDG_00803	1.63e-25	-	-	-	-	-	-	-	-
HILFDMDG_00804	2.27e-213	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HILFDMDG_00805	3.43e-148	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
HILFDMDG_00806	1.26e-91	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
HILFDMDG_00807	2.02e-55	-	-	-	S	ko:K09790	-	ko00000	Protein of unknown function (DUF454)
HILFDMDG_00808	0.0	-	-	-	I	-	-	-	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HILFDMDG_00809	1.01e-194	endA	-	-	V	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
HILFDMDG_00810	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
HILFDMDG_00812	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HILFDMDG_00813	8.97e-292	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
HILFDMDG_00814	6.83e-157	-	-	-	S	-	-	-	SNARE associated Golgi protein
HILFDMDG_00815	0.0	uvrA2	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC, A subunit
HILFDMDG_00816	5.16e-72	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HILFDMDG_00817	2.94e-75	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HILFDMDG_00818	4.81e-90	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HILFDMDG_00819	2.72e-174	-	-	-	S	-	-	-	DUF218 domain
HILFDMDG_00820	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	ABC1 family
HILFDMDG_00821	2.75e-316	yhdP	-	-	S	-	-	-	Transporter associated domain
HILFDMDG_00822	2.39e-98	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
HILFDMDG_00823	5.59e-307	-	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HILFDMDG_00824	6.68e-98	-	-	-	S	-	-	-	UPF0756 membrane protein
HILFDMDG_00825	1.06e-104	-	-	-	S	-	-	-	Cupin domain
HILFDMDG_00826	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
HILFDMDG_00827	4.67e-147	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HILFDMDG_00828	1.83e-59	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HILFDMDG_00829	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HILFDMDG_00830	2.98e-104	-	-	-	S	ko:K19055	-	ko00000,ko01000,ko03016	YbaK proline--tRNA ligase associated domain protein
HILFDMDG_00831	0.0	-	-	-	E	-	-	-	amino acid
HILFDMDG_00832	0.0	ydaO	-	-	E	-	-	-	amino acid
HILFDMDG_00833	1.78e-51	-	-	-	-	-	-	-	-
HILFDMDG_00834	9.89e-86	-	-	-	K	-	-	-	Transcriptional regulator
HILFDMDG_00835	5.74e-31	-	-	-	EGP	-	-	-	Major Facilitator
HILFDMDG_00836	1.33e-110	-	-	-	EGP	-	-	-	Major Facilitator
HILFDMDG_00837	3.26e-95	-	-	-	EGP	-	-	-	Major Facilitator
HILFDMDG_00838	9.45e-145	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
HILFDMDG_00839	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
HILFDMDG_00840	1.98e-163	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
HILFDMDG_00841	5e-124	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HILFDMDG_00842	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HILFDMDG_00843	1.11e-238	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HILFDMDG_00844	2.47e-65	-	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain protein
HILFDMDG_00845	1.88e-68	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
HILFDMDG_00846	2.29e-225	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HILFDMDG_00847	3.18e-198	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HILFDMDG_00848	2.31e-234	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
HILFDMDG_00849	1.08e-215	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HILFDMDG_00850	2.5e-175	lutC	-	-	S	ko:K00782	-	ko00000	LUD domain
HILFDMDG_00851	0.0	lutB	-	-	C	ko:K18929	-	ko00000	4Fe-4S dicluster domain
HILFDMDG_00852	1.2e-200	lutA	-	-	C	ko:K18928	-	ko00000	Cysteine-rich domain
HILFDMDG_00853	3.37e-222	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HILFDMDG_00854	2.65e-268	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
HILFDMDG_00855	2.53e-209	-	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	PFAM extracellular solute-binding protein, family 3
HILFDMDG_00856	1.36e-112	ykhA	3.1.2.20	-	I	ko:K01073	-	ko00000,ko01000	Thioesterase superfamily
HILFDMDG_00857	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HILFDMDG_00858	3.7e-133	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HILFDMDG_00859	1.02e-98	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
HILFDMDG_00860	1.46e-112	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HILFDMDG_00861	1.71e-105	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
HILFDMDG_00862	1.97e-228	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
HILFDMDG_00863	7.51e-174	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HILFDMDG_00864	3.91e-136	-	-	-	-	-	-	-	-
HILFDMDG_00865	7.73e-109	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HILFDMDG_00866	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HILFDMDG_00867	1.1e-185	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Serine aminopeptidase, S33
HILFDMDG_00868	1.43e-47	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HILFDMDG_00869	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HILFDMDG_00870	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
HILFDMDG_00871	0.0	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HILFDMDG_00872	1.02e-181	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HILFDMDG_00873	7.62e-290	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
HILFDMDG_00874	5.33e-243	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HILFDMDG_00876	4.72e-134	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HILFDMDG_00877	4.11e-308	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	Major Facilitator Superfamily
HILFDMDG_00878	1.83e-21	-	-	-	-	-	-	-	-
HILFDMDG_00880	1.37e-218	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
HILFDMDG_00881	1.41e-239	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
HILFDMDG_00882	3.83e-206	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
HILFDMDG_00883	0.0	steT	-	-	E	ko:K03294	-	ko00000	amino acid
HILFDMDG_00884	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HILFDMDG_00885	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HILFDMDG_00886	1.03e-19	-	-	-	-	-	-	-	-
HILFDMDG_00887	3.57e-150	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
HILFDMDG_00889	3.45e-88	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HILFDMDG_00890	9.67e-49	-	-	-	S	-	-	-	Domain of unknown function (DUF4440)
HILFDMDG_00891	4.45e-185	qacA	-	-	EGP	-	-	-	Fungal trichothecene efflux pump (TRI12)
HILFDMDG_00892	1.94e-46	qacA	-	-	EGP	-	-	-	Fungal trichothecene efflux pump (TRI12)
HILFDMDG_00893	5.16e-53	-	-	-	S	-	-	-	Hexapeptide repeat of succinyl-transferase
HILFDMDG_00894	3.8e-160	-	-	-	C	-	-	-	Aldo keto reductase
HILFDMDG_00895	4.64e-112	-	-	-	GM	-	-	-	NAD(P)H-binding
HILFDMDG_00896	1.43e-174	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
HILFDMDG_00897	2.84e-239	-	-	-	L	ko:K07482	-	ko00000	Helix-turn-helix domain
HILFDMDG_00898	3.15e-146	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
HILFDMDG_00899	2.3e-52	-	-	-	S	-	-	-	Cytochrome b5-like Heme/Steroid binding domain
HILFDMDG_00900	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
HILFDMDG_00901	1.69e-233	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HILFDMDG_00903	1.45e-131	-	-	-	S	ko:K07002	-	ko00000	Serine hydrolase
HILFDMDG_00904	1.26e-82	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
HILFDMDG_00905	1.68e-179	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HILFDMDG_00907	3.98e-229	ydhF	-	-	S	-	-	-	Aldo keto reductase
HILFDMDG_00908	1.53e-108	-	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	PAP2 superfamily
HILFDMDG_00909	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
HILFDMDG_00911	0.0	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
HILFDMDG_00912	2.84e-73	-	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
HILFDMDG_00913	1.01e-160	-	-	-	-	-	-	-	-
HILFDMDG_00914	1.31e-161	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
HILFDMDG_00915	0.0	cadA	-	-	P	-	-	-	P-type ATPase
HILFDMDG_00916	1.17e-270	-	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
HILFDMDG_00917	1.84e-95	ywnA	-	-	K	-	-	-	Transcriptional regulator
HILFDMDG_00918	5.08e-207	proWY	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, QAT family
HILFDMDG_00919	5.77e-140	proWZ	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HILFDMDG_00920	1.68e-179	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HILFDMDG_00921	1.13e-137	-	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, permease protein
HILFDMDG_00922	3.14e-103	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
HILFDMDG_00923	5.17e-32	-	-	-	S	-	-	-	Acyltransferase family
HILFDMDG_00925	4.77e-57	-	-	-	S	-	-	-	Glycosyltransferase like family 2
HILFDMDG_00926	1.56e-32	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
HILFDMDG_00927	4.77e-36	-	-	-	M	-	-	-	PFAM Glycosyl transferase family 2
HILFDMDG_00928	1.11e-32	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
HILFDMDG_00929	7.81e-85	cps2I	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HILFDMDG_00931	8.02e-50	-	-	-	M	-	-	-	Glycosyltransferase GT-D fold
HILFDMDG_00932	5.88e-82	wefC	-	-	M	-	-	-	Stealth protein CR2, conserved region 2
HILFDMDG_00933	2.14e-104	-	-	GT4	G	ko:K19422	-	ko00000,ko01000	Glycosyl transferase 4-like domain
HILFDMDG_00934	2.35e-62	-	-	-	M	ko:K13012	-	ko00000,ko01005	Bacterial sugar transferase
HILFDMDG_00935	4.28e-140	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
HILFDMDG_00936	5.31e-127	epsB	-	-	M	-	-	-	biosynthesis protein
HILFDMDG_00937	4.48e-56	-	-	-	L	ko:K07482	-	ko00000	Helix-turn-helix domain
HILFDMDG_00938	6.56e-97	-	-	-	S	-	-	-	polysaccharide biosynthetic process
HILFDMDG_00939	6.01e-54	-	-	-	M	-	-	-	Capsular polysaccharide synthesis protein
HILFDMDG_00940	2.34e-44	-	-	-	M	-	-	-	Glycosyl transferase, family 2
HILFDMDG_00942	4.28e-94	-	-	-	M	-	-	-	Glycosyl transferase family 2
HILFDMDG_00943	1.79e-66	capM	-	-	M	ko:K13012	-	ko00000,ko01005	Bacterial sugar transferase
HILFDMDG_00944	1.75e-153	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
HILFDMDG_00945	1.2e-185	epsB	-	-	M	-	-	-	biosynthesis protein
HILFDMDG_00946	1.56e-213	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HILFDMDG_00947	3.78e-88	-	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HILFDMDG_00948	5.82e-163	-	-	-	-	-	-	-	-
HILFDMDG_00949	1.14e-53	-	-	-	K	-	-	-	DNA-templated transcription, initiation
HILFDMDG_00950	8.42e-49	-	-	-	K	-	-	-	DNA-templated transcription, initiation
HILFDMDG_00951	1.61e-48	-	-	-	-	-	-	-	-
HILFDMDG_00952	1.28e-124	-	-	-	K	-	-	-	Transcriptional regulator, TetR family
HILFDMDG_00953	6.23e-94	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HILFDMDG_00954	9.99e-31	-	-	-	S	-	-	-	ABC-type transport system involved in multi-copper enzyme maturation permease component
HILFDMDG_00955	3.91e-91	-	-	-	-	-	-	-	-
HILFDMDG_00956	0.0	tagE6	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HILFDMDG_00957	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Poly(Glycerol-phosphate) alpha-glucosyltransferase
HILFDMDG_00958	0.0	sdrF	-	-	M	ko:K14194	ko05150,map05150	ko00000,ko00001	protein which possibly mediates interactions of S.aureus with components of the extracellular matrix of higher eukaryotes
HILFDMDG_00959	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HILFDMDG_00960	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HILFDMDG_00961	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HILFDMDG_00962	3.42e-235	cytR	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	Transcriptional regulator, LacI family
HILFDMDG_00963	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HILFDMDG_00965	1.54e-131	-	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
HILFDMDG_00966	2.15e-267	-	1.5.1.36	-	S	ko:K19784,ko:K22393,ko:K22394	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
HILFDMDG_00967	7.71e-227	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HILFDMDG_00968	9.5e-162	pgm3	-	-	G	-	-	-	phosphoglycerate mutase family
HILFDMDG_00969	1.77e-56	-	-	-	-	-	-	-	-
HILFDMDG_00970	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HILFDMDG_00971	3.46e-265	gldA	1.1.1.6	-	C	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	dehydrogenase
HILFDMDG_00972	1.24e-160	-	-	-	S	-	-	-	Alpha beta hydrolase
HILFDMDG_00973	3.27e-276	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HILFDMDG_00974	1.07e-128	-	-	-	-	-	-	-	-
HILFDMDG_00976	6.67e-158	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
HILFDMDG_00977	7.85e-21	-	-	-	-	-	-	-	-
HILFDMDG_00978	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
HILFDMDG_00979	1.75e-141	nnrE	5.1.99.6	-	H	ko:K17759	-	ko00000,ko01000	Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
HILFDMDG_00980	8.57e-114	-	-	-	-	-	-	-	-
HILFDMDG_00981	2.28e-310	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
HILFDMDG_00982	9.44e-209	yttB	-	-	EGP	-	-	-	Major Facilitator
HILFDMDG_00983	8.12e-144	-	-	-	-	-	-	-	-
HILFDMDG_00984	2.6e-33	-	-	-	-	-	-	-	-
HILFDMDG_00985	3.11e-220	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
HILFDMDG_00986	0.0	-	3.2.1.17	CBM50	NU	ko:K01185,ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HILFDMDG_00987	1.36e-66	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
HILFDMDG_00988	3.96e-49	-	-	-	-	-	-	-	-
HILFDMDG_00989	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HILFDMDG_00990	8.51e-148	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HILFDMDG_00991	1.96e-233	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HILFDMDG_00992	1.07e-112	-	-	-	K	-	-	-	transcriptional regulator (TetR family)
HILFDMDG_00993	7.01e-244	-	-	-	E	-	-	-	Zinc-binding dehydrogenase
HILFDMDG_00994	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HILFDMDG_00996	1.84e-203	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HILFDMDG_00997	9.38e-115	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HILFDMDG_00998	3.53e-158	-	-	-	O	-	-	-	Zinc-dependent metalloprotease
HILFDMDG_00999	7.26e-146	-	-	-	S	-	-	-	Membrane
HILFDMDG_01000	3.12e-250	-	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HILFDMDG_01001	4.44e-117	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
HILFDMDG_01002	3.7e-19	-	-	-	-	-	-	-	-
HILFDMDG_01003	3.17e-249	thiP	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
HILFDMDG_01004	8.11e-121	-	-	-	K	-	-	-	PFAM GCN5-related N-acetyltransferase
HILFDMDG_01005	7.05e-77	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HILFDMDG_01006	1.07e-111	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HILFDMDG_01007	2.32e-104	-	-	-	-	-	-	-	-
HILFDMDG_01008	4.74e-164	-	-	-	M	-	-	-	Lysin motif
HILFDMDG_01009	1.55e-254	-	-	-	EGP	-	-	-	Major Facilitator
HILFDMDG_01010	3.62e-131	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
HILFDMDG_01011	1.71e-252	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
HILFDMDG_01012	7.66e-103	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
HILFDMDG_01013	3.4e-196	-	-	-	J	-	-	-	Methyltransferase
HILFDMDG_01014	1.87e-43	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HILFDMDG_01015	2.38e-85	-	-	-	L	-	-	-	Transposase
HILFDMDG_01016	1.74e-190	-	-	-	L	-	-	-	Transposase
HILFDMDG_01017	4.7e-282	-	-	-	L	-	-	-	transposase IS116 IS110 IS902 family protein
HILFDMDG_01019	6.36e-64	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HILFDMDG_01020	1.77e-198	metF	1.5.1.20	-	C	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Methylenetetrahydrofolate reductase
HILFDMDG_01021	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HILFDMDG_01022	9.37e-152	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HILFDMDG_01023	2.6e-215	cpsY	-	-	K	-	-	-	Transcriptional regulator, LysR family
HILFDMDG_01024	7.98e-253	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
HILFDMDG_01025	1.21e-207	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
HILFDMDG_01026	3.75e-124	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HILFDMDG_01027	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HILFDMDG_01028	4.47e-16	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
HILFDMDG_01029	8.07e-76	-	-	-	-	-	-	-	-
HILFDMDG_01030	8.67e-101	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HILFDMDG_01031	2.29e-224	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HILFDMDG_01032	5.99e-74	ftsL	-	-	D	-	-	-	Cell division protein FtsL
HILFDMDG_01033	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HILFDMDG_01034	1.1e-229	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HILFDMDG_01035	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HILFDMDG_01036	1.7e-259	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HILFDMDG_01037	1.73e-185	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HILFDMDG_01038	0.0	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HILFDMDG_01039	6.52e-289	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HILFDMDG_01040	1.29e-91	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HILFDMDG_01041	1.11e-54	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
HILFDMDG_01042	3.71e-190	ylmH	-	-	S	-	-	-	S4 domain protein
HILFDMDG_01043	3.3e-76	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
HILFDMDG_01044	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HILFDMDG_01045	5.69e-44	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
HILFDMDG_01046	1.01e-128	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
HILFDMDG_01047	1.54e-33	-	-	-	-	-	-	-	-
HILFDMDG_01048	9.75e-162	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HILFDMDG_01049	7.42e-277	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HILFDMDG_01050	2.27e-75	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
HILFDMDG_01051	8.77e-286	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HILFDMDG_01052	1.15e-158	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
HILFDMDG_01053	3.82e-157	-	-	-	S	-	-	-	repeat protein
HILFDMDG_01054	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HILFDMDG_01055	1.48e-223	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HILFDMDG_01056	3.08e-241	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HILFDMDG_01057	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HILFDMDG_01058	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HILFDMDG_01059	2.66e-111	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HILFDMDG_01060	6.66e-283	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HILFDMDG_01061	3.25e-223	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HILFDMDG_01062	3.82e-182	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HILFDMDG_01063	3.27e-276	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HILFDMDG_01064	1.82e-254	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HILFDMDG_01065	8.8e-264	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
HILFDMDG_01066	1.25e-74	-	-	-	-	-	-	-	-
HILFDMDG_01068	1.84e-234	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
HILFDMDG_01069	7.27e-38	-	-	-	-	-	-	-	-
HILFDMDG_01070	1.45e-230	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic
HILFDMDG_01071	9.99e-44	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
HILFDMDG_01072	8.99e-104	-	-	-	-	-	-	-	-
HILFDMDG_01073	2.38e-133	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HILFDMDG_01074	9.95e-267	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
HILFDMDG_01075	3.28e-232	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
HILFDMDG_01076	1.06e-311	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HILFDMDG_01077	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
HILFDMDG_01078	5.79e-62	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
HILFDMDG_01079	4.1e-176	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
HILFDMDG_01080	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
HILFDMDG_01081	1.85e-284	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HILFDMDG_01082	5.25e-59	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
HILFDMDG_01083	9.66e-129	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
HILFDMDG_01084	3.05e-116	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HILFDMDG_01085	6.33e-254	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
HILFDMDG_01086	1.97e-137	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
HILFDMDG_01087	2.47e-116	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
HILFDMDG_01088	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
HILFDMDG_01089	5.37e-192	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
HILFDMDG_01090	1.44e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
HILFDMDG_01091	1.74e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HILFDMDG_01092	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HILFDMDG_01093	2.32e-204	-	-	-	S	-	-	-	Tetratricopeptide repeat
HILFDMDG_01094	4.94e-288	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HILFDMDG_01095	5.54e-303	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HILFDMDG_01096	1.19e-296	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HILFDMDG_01097	2.01e-139	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
HILFDMDG_01098	1.11e-78	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
HILFDMDG_01099	2.44e-20	-	-	-	-	-	-	-	-
HILFDMDG_01100	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HILFDMDG_01101	0.0	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HILFDMDG_01102	2.39e-226	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HILFDMDG_01103	1.35e-200	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
HILFDMDG_01104	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
HILFDMDG_01105	2.94e-118	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HILFDMDG_01106	3.77e-123	-	-	-	-	-	-	-	-
HILFDMDG_01108	5.93e-163	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HILFDMDG_01109	1.66e-269	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
HILFDMDG_01110	2.52e-148	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HILFDMDG_01111	2.22e-46	ynzC	-	-	S	-	-	-	UPF0291 protein
HILFDMDG_01112	1.6e-40	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
HILFDMDG_01113	1.84e-152	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
HILFDMDG_01114	1.69e-181	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
HILFDMDG_01115	1.32e-62	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
HILFDMDG_01116	4.85e-232	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HILFDMDG_01117	3.54e-184	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
HILFDMDG_01118	3.14e-197	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HILFDMDG_01119	1.81e-166	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HILFDMDG_01120	1.72e-122	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HILFDMDG_01121	1.29e-182	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HILFDMDG_01122	2.37e-177	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
HILFDMDG_01123	1.15e-298	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
HILFDMDG_01124	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HILFDMDG_01125	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HILFDMDG_01126	1.56e-108	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
HILFDMDG_01127	1.38e-273	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HILFDMDG_01128	5.93e-60	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
HILFDMDG_01129	1.96e-65	ylxQ	-	-	J	-	-	-	ribosomal protein
HILFDMDG_01130	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HILFDMDG_01131	1.38e-77	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HILFDMDG_01132	4.95e-215	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HILFDMDG_01133	7.37e-224	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HILFDMDG_01134	1.26e-84	-	-	-	-	-	-	-	-
HILFDMDG_01135	4.58e-247	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HILFDMDG_01136	8.1e-118	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HILFDMDG_01137	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HILFDMDG_01138	1.55e-273	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HILFDMDG_01139	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HILFDMDG_01140	0.0	pepD3	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HILFDMDG_01141	4.3e-256	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
HILFDMDG_01142	3.37e-222	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HILFDMDG_01143	6.77e-77	-	-	-	-	-	-	-	-
HILFDMDG_01144	8.04e-230	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
HILFDMDG_01145	5.13e-162	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HILFDMDG_01146	5.61e-71	-	-	-	-	-	-	-	-
HILFDMDG_01147	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HILFDMDG_01148	1.88e-101	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HILFDMDG_01149	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HILFDMDG_01150	5.58e-249	tnp2	-	-	L	-	-	-	PFAM Transposase, IS204 IS1001 IS1096 IS1165
HILFDMDG_01151	3.47e-233	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
HILFDMDG_01152	4.8e-128	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HILFDMDG_01153	4.25e-80	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
HILFDMDG_01154	5.65e-143	-	-	-	I	-	-	-	Acid phosphatase homologues
HILFDMDG_01155	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
HILFDMDG_01156	3.39e-293	-	-	-	P	-	-	-	Chloride transporter, ClC family
HILFDMDG_01157	5.25e-149	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HILFDMDG_01158	1.61e-185	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HILFDMDG_01159	1.56e-113	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HILFDMDG_01160	6.49e-65	-	-	-	-	-	-	-	-
HILFDMDG_01165	9.03e-33	-	-	-	K	-	-	-	Peptidase S24-like
HILFDMDG_01166	0.0002	cro	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
HILFDMDG_01169	4.8e-114	-	-	-	K	ko:K07741	-	ko00000	BRO family, N-terminal domain
HILFDMDG_01174	3.71e-66	-	-	-	S	-	-	-	ERF superfamily
HILFDMDG_01175	9.95e-14	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-strand binding protein family
HILFDMDG_01176	1.45e-30	-	-	-	L	-	-	-	DnaD domain protein
HILFDMDG_01177	4.16e-81	-	-	-	L	ko:K02315	-	ko00000,ko03032	IstB-like ATP binding protein
HILFDMDG_01180	2.4e-32	-	-	-	S	-	-	-	Protein of unknown function (DUF1064)
HILFDMDG_01181	3.26e-64	-	-	-	S	-	-	-	ORF6C domain
HILFDMDG_01183	1.24e-22	-	-	-	-	-	-	-	-
HILFDMDG_01188	2.03e-242	gtf2	-	-	M	-	-	-	A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
HILFDMDG_01189	2.86e-286	gtf1	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
HILFDMDG_01190	0.0	secA2	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HILFDMDG_01191	3.67e-198	asp3	-	-	S	ko:K12270	-	ko00000,ko02044	Accessory Sec secretory system ASP3
HILFDMDG_01192	3.53e-269	asp2	-	-	S	ko:K12269	-	ko00000,ko02044	Accessory Sec system GspB-transporter
HILFDMDG_01193	4.23e-247	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HILFDMDG_01194	1.77e-205	secY2	-	-	U	-	-	-	Part of the accessory SecA2 SecY2 system specifically required for export of
HILFDMDG_01195	5.31e-139	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HILFDMDG_01196	6.6e-55	-	-	-	M	-	-	-	family 8
HILFDMDG_01198	4.86e-167	-	-	-	L	-	-	-	Transposase
HILFDMDG_01200	1.72e-101	-	-	-	S	-	-	-	Phage tail tube protein
HILFDMDG_01204	2.61e-64	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HILFDMDG_01205	4.83e-219	-	-	-	S	-	-	-	Phage capsid family
HILFDMDG_01206	2.77e-83	-	-	-	S	-	-	-	Clp protease
HILFDMDG_01207	7.4e-245	-	-	-	S	-	-	-	Phage portal protein
HILFDMDG_01208	0.0	terL	-	-	S	-	-	-	overlaps another CDS with the same product name
HILFDMDG_01209	1.49e-85	-	-	-	L	-	-	-	Phage terminase, small subunit
HILFDMDG_01210	2.44e-104	-	-	-	L	-	-	-	HNH nucleases
HILFDMDG_01214	3.15e-108	-	-	-	S	-	-	-	Phage transcriptional regulator, ArpU family
HILFDMDG_01215	3.45e-174	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HILFDMDG_01216	2.06e-185	lysA2	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HILFDMDG_01217	1.79e-43	-	-	-	S	-	-	-	Bacteriophage holin of superfamily 6 (Holin_LLH)
HILFDMDG_01224	5.82e-96	-	-	-	LM	-	-	-	gp58-like protein
HILFDMDG_01225	5.72e-175	-	-	-	M	-	-	-	Prophage endopeptidase tail
HILFDMDG_01226	3.21e-103	-	-	-	S	-	-	-	Phage tail protein
HILFDMDG_01227	3.36e-35	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
HILFDMDG_01228	6.09e-86	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
HILFDMDG_01229	6.69e-98	-	-	-	L	-	-	-	nuclease
HILFDMDG_01230	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
HILFDMDG_01231	1.93e-266	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HILFDMDG_01232	2.05e-185	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
HILFDMDG_01233	0.0	snf	-	-	KL	-	-	-	domain protein
HILFDMDG_01235	1.95e-51	-	-	-	-	ko:K18829	-	ko00000,ko02048	-
HILFDMDG_01236	4.2e-88	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	Toxin-antitoxin system, toxin component, MazF family
HILFDMDG_01238	1.41e-102	-	-	-	O	-	-	-	Bacterial dnaA protein
HILFDMDG_01239	5.46e-74	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HILFDMDG_01240	1.82e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
HILFDMDG_01241	1.07e-110	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HILFDMDG_01242	4.08e-220	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
HILFDMDG_01243	5.97e-302	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
HILFDMDG_01244	2.82e-105	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HILFDMDG_01245	3.99e-127	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HILFDMDG_01246	9.85e-198	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HILFDMDG_01247	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HILFDMDG_01248	2.05e-155	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
HILFDMDG_01249	1.03e-150	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HILFDMDG_01250	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
HILFDMDG_01251	1.34e-151	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HILFDMDG_01252	2.84e-73	ytpP	-	-	CO	-	-	-	Thioredoxin
HILFDMDG_01253	3.23e-75	-	-	-	S	-	-	-	Small secreted protein
HILFDMDG_01254	1.72e-213	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
HILFDMDG_01255	2.96e-207	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HILFDMDG_01256	0.0	-	2.4.1.5	GH13	G	ko:K00689	ko00500,ko02020,map00500,map02020	ko00000,ko00001,ko01000	Glycosyl hydrolase family 70
HILFDMDG_01257	0.0	-	2.4.1.5	GH13	G	ko:K00689	ko00500,ko02020,map00500,map02020	ko00000,ko00001,ko01000	Glycosyl hydrolase family 70
HILFDMDG_01258	3.38e-274	-	-	-	L	-	-	-	Integrase core domain
HILFDMDG_01279	3.75e-103	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
HILFDMDG_01280	2.02e-88	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HILFDMDG_01281	9.02e-154	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HILFDMDG_01282	3.84e-147	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
HILFDMDG_01283	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HILFDMDG_01284	8.42e-149	yjbH	-	-	Q	-	-	-	Thioredoxin
HILFDMDG_01285	1.29e-150	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
HILFDMDG_01286	1.46e-196	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HILFDMDG_01287	4.11e-223	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HILFDMDG_01290	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HILFDMDG_01291	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
HILFDMDG_01292	1.89e-35	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
HILFDMDG_01293	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HILFDMDG_01294	1.11e-106	-	-	-	-	-	-	-	-
HILFDMDG_01295	5.13e-172	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HILFDMDG_01296	7.36e-128	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
HILFDMDG_01297	0.0	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HILFDMDG_01298	5.03e-148	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HILFDMDG_01299	6.5e-71	-	-	-	-	-	-	-	-
HILFDMDG_01300	0.0	nhaK	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HILFDMDG_01301	1.28e-68	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
HILFDMDG_01302	3.6e-241	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
HILFDMDG_01303	1.3e-95	-	-	-	K	-	-	-	Transcriptional regulator
HILFDMDG_01304	3.32e-205	-	-	-	-	-	-	-	-
HILFDMDG_01305	7.31e-43	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
HILFDMDG_01306	1.56e-81	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
HILFDMDG_01307	5.3e-30	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
HILFDMDG_01308	0.0	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system Galactitol-specific IIC component
HILFDMDG_01309	1.37e-270	-	-	-	EGP	-	-	-	Major Facilitator
HILFDMDG_01310	5.96e-149	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HILFDMDG_01311	8.17e-152	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
HILFDMDG_01312	2.98e-10	-	-	-	-	-	-	-	-
HILFDMDG_01313	1.78e-83	-	-	-	-	-	-	-	-
HILFDMDG_01314	4.08e-248	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
HILFDMDG_01315	7.46e-106	uspA3	-	-	T	-	-	-	universal stress protein
HILFDMDG_01316	0.0	fusA1	-	-	J	-	-	-	elongation factor G
HILFDMDG_01317	1.79e-212	-	-	-	GK	-	-	-	ROK family
HILFDMDG_01318	8.36e-312	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HILFDMDG_01319	4.46e-154	yfhR3	-	-	S	ko:K06889	-	ko00000	Serine hydrolase (FSH1)
HILFDMDG_01320	7.11e-309	-	-	-	E	-	-	-	amino acid
HILFDMDG_01321	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
HILFDMDG_01322	1.05e-171	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
HILFDMDG_01323	2.85e-114	ebsC	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HILFDMDG_01324	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HILFDMDG_01325	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HILFDMDG_01326	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HILFDMDG_01327	3.33e-241	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HILFDMDG_01328	1.7e-173	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HILFDMDG_01329	2.34e-187	-	-	-	-	-	-	-	-
HILFDMDG_01330	2.34e-203	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
HILFDMDG_01331	5.61e-238	XK27_12525	-	-	S	-	-	-	AI-2E family transporter
HILFDMDG_01332	9.04e-172	XK27_07210	-	-	S	-	-	-	B3 4 domain
HILFDMDG_01333	1.93e-101	yybA	-	-	K	-	-	-	Transcriptional regulator
HILFDMDG_01334	5.25e-118	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
HILFDMDG_01335	1.63e-116	-	-	-	GM	-	-	-	epimerase
HILFDMDG_01336	1.98e-198	-	-	-	V	-	-	-	(ABC) transporter
HILFDMDG_01337	8.65e-310	yhdP	-	-	S	-	-	-	Transporter associated domain
HILFDMDG_01338	4e-110	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
HILFDMDG_01339	4.3e-96	-	-	-	S	ko:K04750	-	ko00000	3-demethylubiquinone-9 3-methyltransferase
HILFDMDG_01340	5.09e-244	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
HILFDMDG_01341	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HILFDMDG_01342	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HILFDMDG_01343	4.85e-52	-	-	-	-	-	-	-	-
HILFDMDG_01344	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
HILFDMDG_01345	8.43e-301	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HILFDMDG_01346	2.32e-104	usp5	-	-	T	-	-	-	universal stress protein
HILFDMDG_01347	9.78e-107	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	AsnC family
HILFDMDG_01348	2.14e-296	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HILFDMDG_01349	6.28e-134	apl	3.1.3.1	-	S	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	SNARE associated Golgi protein
HILFDMDG_01350	3.13e-228	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HILFDMDG_01351	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
HILFDMDG_01352	1.47e-287	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HILFDMDG_01353	3.14e-226	celE3	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HILFDMDG_01354	7.76e-187	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HILFDMDG_01355	5.55e-121	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
HILFDMDG_01356	1.21e-48	-	-	-	-	-	-	-	-
HILFDMDG_01357	1.76e-68	-	-	-	-	-	-	-	-
HILFDMDG_01358	4.14e-257	-	-	-	-	-	-	-	-
HILFDMDG_01359	5.53e-106	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HILFDMDG_01360	1.38e-175	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
HILFDMDG_01361	4.18e-201	yvgN	-	-	S	-	-	-	Aldo keto reductase
HILFDMDG_01362	1.06e-161	XK27_10500	-	-	K	-	-	-	response regulator
HILFDMDG_01363	1.19e-230	kinG	-	-	T	-	-	-	Histidine kinase-like ATPases
HILFDMDG_01364	2.48e-174	XK27_05695	-	-	V	ko:K02003,ko:K19083	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HILFDMDG_01365	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HILFDMDG_01366	1.24e-195	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
HILFDMDG_01367	2.95e-210	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HILFDMDG_01368	1.38e-67	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HILFDMDG_01369	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HILFDMDG_01370	2.85e-250	-	-	-	EGP	-	-	-	Major Facilitator
HILFDMDG_01371	1.42e-111	ymdB	-	-	S	-	-	-	Macro domain protein
HILFDMDG_01372	6.11e-142	-	-	-	K	-	-	-	Helix-turn-helix domain
HILFDMDG_01373	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
HILFDMDG_01374	1.21e-63	-	-	-	-	-	-	-	-
HILFDMDG_01375	1.19e-294	-	-	-	S	-	-	-	Putative metallopeptidase domain
HILFDMDG_01376	6.33e-256	-	-	-	S	-	-	-	associated with various cellular activities
HILFDMDG_01377	2.34e-154	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
HILFDMDG_01378	8.5e-86	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
HILFDMDG_01380	6.52e-149	yrkL	-	-	S	-	-	-	Flavodoxin-like fold
HILFDMDG_01381	3.32e-72	-	-	-	-	-	-	-	-
HILFDMDG_01383	2.62e-175	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
HILFDMDG_01384	2.04e-65	-	-	-	-	-	-	-	-
HILFDMDG_01385	1.62e-256	yngD	-	-	S	ko:K07097	-	ko00000	DHHA1 domain
HILFDMDG_01386	1.81e-293	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
HILFDMDG_01387	1.24e-314	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HILFDMDG_01388	5.99e-137	-	-	-	NU	-	-	-	mannosyl-glycoprotein
HILFDMDG_01389	7.4e-180	-	-	-	S	-	-	-	Putative ABC-transporter type IV
HILFDMDG_01390	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
HILFDMDG_01391	1.36e-118	-	-	-	K	-	-	-	Helix-turn-helix domain
HILFDMDG_01392	4.75e-64	-	-	-	-	-	-	-	-
HILFDMDG_01394	2.21e-27	nrdI	-	-	F	ko:K03647	-	ko00000	NrdI Flavodoxin like
HILFDMDG_01395	6.21e-51	-	-	-	M	-	-	-	Sortase family
HILFDMDG_01396	6.85e-95	-	-	-	K	-	-	-	Transcriptional regulator, TetR family
HILFDMDG_01397	2.55e-169	-	-	-	M	-	-	-	PFAM NLP P60 protein
HILFDMDG_01398	3.69e-232	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
HILFDMDG_01399	1.18e-196	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HILFDMDG_01400	1.33e-175	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HILFDMDG_01401	1.93e-119	-	-	-	P	-	-	-	Cadmium resistance transporter
HILFDMDG_01402	1.09e-72	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
HILFDMDG_01403	2.54e-71	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HILFDMDG_01404	3.78e-169	yceF	-	-	P	ko:K05794	-	ko00000	membrane
HILFDMDG_01405	2.27e-218	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
HILFDMDG_01406	8.21e-216	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HILFDMDG_01407	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HILFDMDG_01408	4.79e-307	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
HILFDMDG_01409	3.99e-315	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
HILFDMDG_01410	0.0	-	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
HILFDMDG_01411	1.88e-260	-	-	-	L	-	-	-	Integrase core domain
HILFDMDG_01412	1.75e-179	-	-	-	L	-	-	-	Bacterial dnaA protein
HILFDMDG_01413	9.04e-56	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HILFDMDG_01414	3.3e-91	M1-798	-	-	K	-	-	-	Rhodanese Homology Domain
HILFDMDG_01415	2.9e-33	-	-	-	CO	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	cell redox homeostasis
HILFDMDG_01416	8.86e-177	trxB	1.8.1.9	-	O	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Glucose inhibited division protein A
HILFDMDG_01417	1.01e-122	frnE	5.3.4.1	-	Q	ko:K01829	-	ko00000,ko01000	dithiol-disulfide isomerase involved in polyketide biosynthesis
HILFDMDG_01419	3.92e-52	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HILFDMDG_01420	7.72e-49	ytpP	-	-	CO	-	-	-	Thioredoxin
HILFDMDG_01421	4.13e-147	-	-	-	S	-	-	-	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
HILFDMDG_01423	8.19e-70	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
HILFDMDG_01424	2.61e-21	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
HILFDMDG_01425	2.21e-155	-	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
HILFDMDG_01426	8.35e-119	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
HILFDMDG_01427	7.88e-245	flp	-	-	V	-	-	-	Beta-lactamase
HILFDMDG_01428	1.03e-96	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HILFDMDG_01429	6.28e-116	-	-	-	J	ko:K19055	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
HILFDMDG_01430	5.25e-27	-	-	-	L	-	-	-	Addiction module antitoxin, RelB DinJ family
HILFDMDG_01431	9.98e-24	-	-	-	-	-	-	-	-
HILFDMDG_01433	9.13e-124	-	-	-	-	-	-	-	-
HILFDMDG_01434	1.2e-76	-	-	-	-	-	-	-	-
HILFDMDG_01435	9.95e-36	-	-	-	-	-	-	-	-
HILFDMDG_01436	1.01e-191	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
HILFDMDG_01437	7.63e-156	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HILFDMDG_01438	1.18e-134	-	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
HILFDMDG_01439	3.03e-91	-	-	-	-	-	-	-	-
HILFDMDG_01440	1.5e-102	XK27_00340	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HILFDMDG_01442	1.57e-236	-	-	-	-	-	-	-	-
HILFDMDG_01443	2.71e-125	-	-	-	K	-	-	-	acetyltransferase
HILFDMDG_01444	4.68e-90	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HILFDMDG_01446	1.18e-221	-	-	-	-	-	-	-	-
HILFDMDG_01448	3.81e-59	ysdA	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	transmembrane transport
HILFDMDG_01449	7.79e-89	ysdB	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	Domain of unknown function (DUF4162)
HILFDMDG_01450	7.3e-125	-	-	-	L	-	-	-	Transposase
HILFDMDG_01451	1.58e-28	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix domain
HILFDMDG_01452	5.37e-74	-	-	-	S	-	-	-	Pfam:DUF59
HILFDMDG_01453	1.94e-248	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HILFDMDG_01454	3e-113	moaC	4.6.1.17	-	H	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HILFDMDG_01455	2.42e-116	-	-	-	L	-	-	-	Integrase
HILFDMDG_01456	6.01e-17	XK27_09155	-	-	K	-	-	-	Transcriptional
HILFDMDG_01457	1.02e-70	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	type I restriction modification DNA specificity domain
HILFDMDG_01458	6.85e-227	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HILFDMDG_01459	4.41e-113	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain protein
HILFDMDG_01460	7.94e-51	axe	-	-	K	ko:K21498	-	ko00000,ko02048	Helix-turn-helix XRE-family like proteins
HILFDMDG_01461	1.29e-59	-	-	-	S	ko:K07334	-	ko00000,ko02048	RelE-like toxin of type II toxin-antitoxin system HigB
HILFDMDG_01462	1.5e-40	-	2.1.1.72, 3.1.21.3	AA10,CBM73	L	ko:K01154,ko:K03933,ko:K07316	-	ko00000,ko01000,ko02048	Belongs to the N(4) N(6)-methyltransferase family
HILFDMDG_01463	1.41e-295	-	-	-	S	-	-	-	amidohydrolase
HILFDMDG_01464	1.26e-24	-	-	-	S	-	-	-	amidohydrolase
HILFDMDG_01465	8.44e-70	-	-	-	K	-	-	-	LysR substrate binding domain
HILFDMDG_01467	1.57e-10	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
HILFDMDG_01468	4.8e-140	-	-	-	L	-	-	-	Transposase
HILFDMDG_01469	0.0	-	-	-	O	-	-	-	Arylsulfotransferase (ASST)
HILFDMDG_01470	1.58e-314	-	-	-	E	-	-	-	amino acid
HILFDMDG_01471	8.02e-174	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
HILFDMDG_01473	1.82e-122	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HILFDMDG_01474	1.47e-120	-	-	-	-	-	-	-	-
HILFDMDG_01475	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HILFDMDG_01476	4.32e-232	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HILFDMDG_01477	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
HILFDMDG_01478	6.51e-114	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
HILFDMDG_01479	0.0	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
HILFDMDG_01480	1.86e-63	-	-	-	S	-	-	-	Cupin 2, conserved barrel domain protein
HILFDMDG_01481	1.8e-215	-	-	-	C	-	-	-	Aldo keto reductase
HILFDMDG_01482	3.7e-176	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
HILFDMDG_01483	0.0	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
HILFDMDG_01484	8.72e-155	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
HILFDMDG_01485	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
HILFDMDG_01486	0.0	malT	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HILFDMDG_01487	2.87e-269	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
HILFDMDG_01488	3e-221	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
HILFDMDG_01489	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
HILFDMDG_01490	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HILFDMDG_01491	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HILFDMDG_01492	4.76e-137	-	-	-	K	-	-	-	PFAM GCN5-related N-acetyltransferase
HILFDMDG_01494	2.53e-209	menC	4.2.1.113	-	H	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
HILFDMDG_01495	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	associated with various cellular activities
HILFDMDG_01496	8.68e-44	-	-	-	-	-	-	-	-
HILFDMDG_01497	9.3e-272	-	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HILFDMDG_01498	2.78e-227	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HILFDMDG_01499	9.74e-98	-	-	-	O	-	-	-	OsmC-like protein
HILFDMDG_01501	2.3e-308	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HILFDMDG_01504	1.43e-175	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HILFDMDG_01505	1.19e-249	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HILFDMDG_01508	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
HILFDMDG_01509	1.75e-65	-	-	-	-	-	-	-	-
HILFDMDG_01511	8.65e-276	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HILFDMDG_01512	4.85e-167	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HILFDMDG_01513	2.03e-200	hlyD3	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HILFDMDG_01514	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HILFDMDG_01515	2.05e-187	-	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HILFDMDG_01516	5.08e-191	-	-	-	E	-	-	-	Glyoxalase-like domain
HILFDMDG_01517	8.4e-200	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
HILFDMDG_01518	1.03e-286	dhaT	1.1.1.202	-	C	ko:K00086	ko00561,ko00640,map00561,map00640	ko00000,ko00001,ko01000	Dehydrogenase
HILFDMDG_01519	1.1e-125	-	-	-	S	-	-	-	reductase
HILFDMDG_01520	2.63e-115	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HILFDMDG_01521	4.29e-25	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
HILFDMDG_01522	5.79e-117	pgpA	-	-	I	-	-	-	Phosphatidylglycerophosphatase A
HILFDMDG_01523	4.53e-283	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
HILFDMDG_01524	2.94e-195	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
HILFDMDG_01525	5.03e-193	yycI	-	-	S	-	-	-	YycH protein
HILFDMDG_01526	3.38e-315	yycH	-	-	S	-	-	-	YycH protein
HILFDMDG_01527	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HILFDMDG_01528	2.6e-168	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HILFDMDG_01530	3.97e-206	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
HILFDMDG_01531	9.72e-58	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
HILFDMDG_01532	7.66e-96	-	-	-	K	ko:K18909	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
HILFDMDG_01534	7.88e-158	-	-	-	S	-	-	-	Fic/DOC family
HILFDMDG_01535	2.17e-209	-	-	-	S	-	-	-	Polyphosphate nucleotide phosphotransferase, PPK2 family
HILFDMDG_01536	3.81e-311	aldA	1.2.1.21, 1.2.1.22	-	C	ko:K07248	ko00620,ko00630,ko01120,map00620,map00630,map01120	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family
HILFDMDG_01537	3.79e-251	adhC	1.1.1.90	-	C	ko:K00055	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Zn-dependent alcohol dehydrogenases, class III
HILFDMDG_01538	9.43e-73	-	-	-	-	-	-	-	-
HILFDMDG_01539	6.51e-270	yttB	-	-	EGP	-	-	-	Major Facilitator
HILFDMDG_01540	3.65e-308	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HILFDMDG_01541	1.25e-97	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HILFDMDG_01542	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
HILFDMDG_01543	9.36e-48	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HILFDMDG_01544	2.82e-112	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HILFDMDG_01545	4.55e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
HILFDMDG_01546	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HILFDMDG_01547	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HILFDMDG_01548	1.7e-261	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HILFDMDG_01549	5.41e-47	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
HILFDMDG_01550	8.13e-263	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HILFDMDG_01551	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HILFDMDG_01552	7.96e-21	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
HILFDMDG_01553	1.39e-76	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HILFDMDG_01554	2.96e-172	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HILFDMDG_01555	3.89e-156	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HILFDMDG_01556	6.57e-163	-	-	-	L	-	-	-	Helix-turn-helix domain
HILFDMDG_01557	2.18e-170	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
HILFDMDG_01558	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HILFDMDG_01559	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HILFDMDG_01560	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HILFDMDG_01561	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HILFDMDG_01562	4.26e-314	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
HILFDMDG_01563	2.44e-147	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HILFDMDG_01564	9.23e-116	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase, GNAT family
HILFDMDG_01565	9.53e-206	-	-	-	S	-	-	-	reductase
HILFDMDG_01568	0.0	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
HILFDMDG_01569	3.02e-85	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
HILFDMDG_01571	1.79e-212	-	-	-	G	-	-	-	Phosphotransferase enzyme family
HILFDMDG_01572	1.44e-102	int2	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HILFDMDG_01573	7.78e-125	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
HILFDMDG_01574	5.44e-279	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
HILFDMDG_01575	5.4e-63	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
HILFDMDG_01576	8.13e-157	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HILFDMDG_01577	8.83e-147	yqeK	-	-	H	-	-	-	Hydrolase, HD family
HILFDMDG_01578	2.69e-79	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HILFDMDG_01579	2.91e-175	yqeM	-	-	Q	-	-	-	Methyltransferase
HILFDMDG_01580	3.95e-273	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
HILFDMDG_01581	1.01e-129	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
HILFDMDG_01582	7.21e-39	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
HILFDMDG_01583	9.72e-156	csrR	-	-	K	-	-	-	response regulator
HILFDMDG_01584	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HILFDMDG_01585	0.0	potE	-	-	E	-	-	-	Amino Acid
HILFDMDG_01586	1.74e-291	-	-	-	V	-	-	-	MatE
HILFDMDG_01587	3.32e-93	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
HILFDMDG_01588	1.11e-214	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HILFDMDG_01589	2.45e-58	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
HILFDMDG_01590	2.71e-186	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HILFDMDG_01591	3.75e-119	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HILFDMDG_01592	9.63e-77	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HILFDMDG_01593	3.66e-252	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HILFDMDG_01594	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HILFDMDG_01595	2.41e-148	-	-	-	M	-	-	-	PFAM NLP P60 protein
HILFDMDG_01596	2.06e-152	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
HILFDMDG_01597	6.08e-102	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HILFDMDG_01598	9.37e-92	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
HILFDMDG_01599	0.0	-	-	-	S	-	-	-	membrane
HILFDMDG_01600	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HILFDMDG_01601	1.53e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HILFDMDG_01602	6.32e-128	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HILFDMDG_01603	1.13e-145	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
HILFDMDG_01604	7.07e-48	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
HILFDMDG_01605	2.51e-235	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
HILFDMDG_01606	7.66e-88	yqhL	-	-	P	-	-	-	Rhodanese-like protein
HILFDMDG_01607	1.18e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF3042)
HILFDMDG_01608	4.12e-226	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HILFDMDG_01609	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HILFDMDG_01610	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HILFDMDG_01611	1.7e-282	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HILFDMDG_01612	1.28e-18	-	-	-	-	-	-	-	-
HILFDMDG_01613	1.39e-196	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HILFDMDG_01614	9.48e-130	msrA	1.8.4.11	-	C	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HILFDMDG_01615	4.41e-67	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HILFDMDG_01616	4e-202	-	-	-	-	-	-	-	-
HILFDMDG_01617	1.26e-224	-	-	-	-	-	-	-	-
HILFDMDG_01618	1.93e-112	-	-	-	S	-	-	-	Protein conserved in bacteria
HILFDMDG_01621	5.7e-146	-	-	-	K	-	-	-	Transcriptional regulator
HILFDMDG_01622	2.68e-67	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
HILFDMDG_01623	5.08e-72	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
HILFDMDG_01624	7.2e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
HILFDMDG_01625	4.82e-164	-	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HILFDMDG_01626	4.13e-254	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HILFDMDG_01627	1.86e-142	-	-	-	J	-	-	-	2'-5' RNA ligase superfamily
HILFDMDG_01628	1.32e-92	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
HILFDMDG_01629	2.24e-92	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HILFDMDG_01630	6.56e-192	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HILFDMDG_01631	1.09e-309	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HILFDMDG_01632	2.83e-58	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HILFDMDG_01633	3.54e-198	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HILFDMDG_01634	1.97e-191	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
HILFDMDG_01635	2.25e-100	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HILFDMDG_01636	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
HILFDMDG_01637	7.4e-71	-	-	-	-	-	-	-	-
HILFDMDG_01638	4.37e-148	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HILFDMDG_01639	6.66e-43	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HILFDMDG_01640	1.17e-268	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HILFDMDG_01641	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HILFDMDG_01642	2.12e-224	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HILFDMDG_01643	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HILFDMDG_01644	3.5e-167	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
HILFDMDG_01645	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HILFDMDG_01646	1.03e-209	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HILFDMDG_01647	1.5e-149	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
HILFDMDG_01648	8.12e-158	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
HILFDMDG_01649	1.1e-34	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
HILFDMDG_01650	1.05e-77	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HILFDMDG_01651	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
HILFDMDG_01652	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HILFDMDG_01653	1.51e-237	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HILFDMDG_01654	1.81e-50	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HILFDMDG_01655	1.57e-168	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HILFDMDG_01656	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
HILFDMDG_01657	9.45e-282	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HILFDMDG_01658	4.23e-76	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HILFDMDG_01659	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HILFDMDG_01660	1.21e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
HILFDMDG_01661	4.38e-52	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
HILFDMDG_01662	3.46e-115	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HILFDMDG_01663	1.1e-182	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
HILFDMDG_01664	0.0	-	-	-	E	ko:K03294	-	ko00000	amino acid
HILFDMDG_01665	3.03e-83	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HILFDMDG_01666	5.37e-24	-	-	-	-	-	-	-	-
HILFDMDG_01667	9e-72	-	-	-	S	-	-	-	Mazg nucleotide pyrophosphohydrolase
HILFDMDG_01668	9.2e-207	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HILFDMDG_01669	5.42e-110	-	-	-	-	-	-	-	-
HILFDMDG_01670	1.16e-239	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HILFDMDG_01671	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
HILFDMDG_01672	0.0	lacZ	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
HILFDMDG_01673	3.5e-223	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HILFDMDG_01674	8.07e-204	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
HILFDMDG_01676	2.14e-166	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HILFDMDG_01677	1.81e-291	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
HILFDMDG_01678	2.76e-212	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
HILFDMDG_01679	2.48e-57	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HILFDMDG_01681	5.04e-154	sdhB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
HILFDMDG_01682	2.65e-190	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HILFDMDG_01683	6.57e-136	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Peroxiredoxin
HILFDMDG_01684	0.0	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Thioredoxin domain
HILFDMDG_01685	2.07e-164	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HILFDMDG_01686	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HILFDMDG_01687	4.16e-53	-	-	-	S	-	-	-	glycosyl transferase family 2
HILFDMDG_01688	1.27e-61	-	-	-	S	-	-	-	glycosyl transferase family 2
HILFDMDG_01689	0.0	-	-	-	M	-	-	-	family 8
HILFDMDG_01690	5e-178	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HILFDMDG_01691	2.6e-134	-	-	-	L	-	-	-	Transposase
HILFDMDG_01692	4.88e-67	yjdF3	-	-	S	-	-	-	Protein of unknown function (DUF2992)
HILFDMDG_01693	1.42e-31	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HILFDMDG_01694	8.93e-38	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HILFDMDG_01695	1.57e-94	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
HILFDMDG_01696	1.13e-75	-	-	-	-	-	-	-	-
HILFDMDG_01697	2.53e-12	-	-	-	K	-	-	-	LytTr DNA-binding domain
HILFDMDG_01698	6.13e-27	-	-	-	-	-	-	-	-
HILFDMDG_01699	3.78e-23	-	-	-	-	-	-	-	-
HILFDMDG_01700	5.67e-70	-	-	-	S	-	-	-	Belongs to the HesB IscA family
HILFDMDG_01701	8.38e-37	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HILFDMDG_01702	1.67e-58	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HILFDMDG_01703	4.46e-67	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HILFDMDG_01704	4.07e-138	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HILFDMDG_01705	3.85e-311	-	-	-	EGP	-	-	-	Major Facilitator
HILFDMDG_01706	2.92e-107	padR	-	-	K	-	-	-	Transcriptional regulator PadR-like family
HILFDMDG_01708	2.98e-222	-	-	-	L	-	-	-	Plasmid pRiA4b ORF-3-like protein
HILFDMDG_01710	4.65e-78	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
HILFDMDG_01711	8.81e-98	-	-	-	K	-	-	-	LytTr DNA-binding domain
HILFDMDG_01712	9.64e-188	cylB	-	-	V	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
HILFDMDG_01713	4.16e-198	-	-	-	V	ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HILFDMDG_01714	2.2e-61	-	-	-	-	-	-	-	-
HILFDMDG_01716	1.35e-117	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
HILFDMDG_01717	1.75e-311	-	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	pyridine nucleotide-disulfide oxidoreductase
HILFDMDG_01718	1.13e-114	-	-	-	-	-	-	-	-
HILFDMDG_01719	1.4e-154	pnb	-	-	C	-	-	-	nitroreductase
HILFDMDG_01720	7.09e-39	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
HILFDMDG_01721	4.87e-191	-	3.2.1.96, 3.5.1.28	GH73	M	ko:K01227,ko:K01447,ko:K13714,ko:K13731	ko00511,ko05100,map00511,map05100	ko00000,ko00001,ko01000	N-acetylmuramoyl-L-alanine amidase
HILFDMDG_01722	5.12e-96	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
HILFDMDG_01723	9.31e-97	-	-	-	K	-	-	-	LytTr DNA-binding domain
HILFDMDG_01724	3.38e-26	-	-	-	-	-	-	-	-
HILFDMDG_01725	2.17e-151	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HILFDMDG_01726	9.88e-100	yjcF	3.5.4.33, 4.4.1.8	-	K	ko:K02348,ko:K07000,ko:K11991,ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007,ko03016	protein acetylation
HILFDMDG_01727	6.96e-244	-	-	-	S	-	-	-	Protein of unknown function (DUF3114)
HILFDMDG_01728	0.0	gshA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
HILFDMDG_01729	1.31e-213	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HILFDMDG_01730	2.83e-133	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
HILFDMDG_01731	4.62e-81	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
HILFDMDG_01732	2.54e-243	mocA	-	-	S	-	-	-	Oxidoreductase
HILFDMDG_01733	2.11e-293	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
HILFDMDG_01735	1.92e-262	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HILFDMDG_01736	1.42e-72	-	-	-	-	-	-	-	-
HILFDMDG_01737	8.59e-98	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
HILFDMDG_01738	4.7e-103	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
HILFDMDG_01739	1e-215	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
HILFDMDG_01740	2.8e-280	arcT	-	-	E	-	-	-	Aminotransferase
HILFDMDG_01741	0.0	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
HILFDMDG_01742	0.0	potE	-	-	E	-	-	-	Amino Acid
HILFDMDG_01743	1.5e-198	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
HILFDMDG_01744	4.23e-45	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
HILFDMDG_01745	2.53e-42	-	-	-	-	-	-	-	-
HILFDMDG_01746	3.73e-171	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
HILFDMDG_01747	3.17e-188	cps1D	-	-	M	-	-	-	Domain of unknown function (DUF4422)
HILFDMDG_01748	8.95e-222	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
HILFDMDG_01749	3.3e-152	-	-	-	M	-	-	-	Bacterial sugar transferase
HILFDMDG_01750	0.0	spoIIQ	-	-	M	ko:K06386	-	ko00000	Peptidase family M23
HILFDMDG_01751	0.0	-	-	-	G	-	-	-	Peptidase_C39 like family
HILFDMDG_01752	1.57e-46	-	-	-	-	-	-	-	-
HILFDMDG_01753	5.85e-277	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
HILFDMDG_01754	1.62e-263	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
HILFDMDG_01755	8.59e-95	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HILFDMDG_01756	1.23e-107	-	-	-	-	-	-	-	-
HILFDMDG_01757	9.63e-38	-	-	-	M	-	-	-	biosynthesis protein
HILFDMDG_01758	1.56e-95	-	-	GT2	M	ko:K12997	-	ko00000,ko01000,ko01003,ko01005	Glycosyl transferase family 2
HILFDMDG_01759	7.27e-83	-	-	-	S	-	-	-	Glycosyltransferase like family
HILFDMDG_01760	4.99e-98	-	-	-	S	ko:K07011	-	ko00000	Glycosyltransferase, group 2 family protein
HILFDMDG_01761	5.07e-94	-	-	-	-	-	-	-	-
HILFDMDG_01762	3.29e-183	-	-	-	M	-	-	-	Glycosyl transferase family 2
HILFDMDG_01763	0.0	-	-	CBM50	NU	ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HILFDMDG_01765	1.3e-204	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HILFDMDG_01766	9.26e-139	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HILFDMDG_01767	1.99e-264	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HILFDMDG_01768	1.28e-195	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HILFDMDG_01769	0.0	-	-	-	G	-	-	-	Peptidase_C39 like family
HILFDMDG_01770	2.63e-232	yueF	-	-	S	-	-	-	AI-2E family transporter
HILFDMDG_01771	2.18e-297	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HILFDMDG_01772	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HILFDMDG_01773	0.0	-	-	-	M	-	-	-	NlpC/P60 family
HILFDMDG_01774	2.76e-90	-	-	-	S	-	-	-	Peptidase, M23
HILFDMDG_01775	0.0	-	-	-	S	-	-	-	Peptidase, M23
HILFDMDG_01776	7.18e-86	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
HILFDMDG_01777	1.3e-201	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HILFDMDG_01778	5.54e-146	-	-	-	-	-	-	-	-
HILFDMDG_01779	9.48e-183	-	-	-	G	-	-	-	MucBP domain
HILFDMDG_01780	1.75e-127	-	-	-	S	-	-	-	Pfam:DUF3816
HILFDMDG_01781	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
HILFDMDG_01782	1.61e-36	-	-	-	-	-	-	-	-
HILFDMDG_01783	3.69e-54	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
HILFDMDG_01784	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HILFDMDG_01785	3.48e-288	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HILFDMDG_01786	2.67e-251	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HILFDMDG_01787	6.57e-229	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HILFDMDG_01788	1.97e-53	-	-	-	S	-	-	-	Protein of unknown function (DUF1797)
HILFDMDG_01789	1.06e-148	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
HILFDMDG_01790	6.57e-144	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
HILFDMDG_01791	2.05e-180	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HILFDMDG_01792	8.68e-129	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
HILFDMDG_01793	9.97e-152	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HILFDMDG_01794	5.54e-286	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HILFDMDG_01795	9.84e-184	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
HILFDMDG_01796	8.95e-90	-	-	-	-	ko:K02248	-	ko00000,ko00002,ko02044	-
HILFDMDG_01797	4.99e-58	-	-	-	-	-	-	-	-
HILFDMDG_01798	1.01e-100	-	-	-	NU	ko:K02246	-	ko00000,ko00002,ko02044	general secretion pathway protein
HILFDMDG_01799	6.31e-62	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
HILFDMDG_01800	1.95e-229	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
HILFDMDG_01801	2.81e-233	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
HILFDMDG_01802	7.07e-168	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
HILFDMDG_01803	1.91e-177	-	-	-	-	-	-	-	-
HILFDMDG_01804	2.41e-235	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
HILFDMDG_01805	4.22e-267	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HILFDMDG_01806	1.84e-75	-	-	-	-	-	-	-	-
HILFDMDG_01807	1.54e-71	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HILFDMDG_01808	2.65e-189	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
HILFDMDG_01809	3.69e-157	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HILFDMDG_01810	1.24e-20	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HILFDMDG_01811	3.62e-100	ykuL	-	-	S	-	-	-	(CBS) domain
HILFDMDG_01812	3.71e-122	-	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
HILFDMDG_01813	3.47e-135	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HILFDMDG_01814	3.27e-187	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HILFDMDG_01815	2.89e-124	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
HILFDMDG_01816	2.86e-72	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HILFDMDG_01817	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HILFDMDG_01818	8.35e-121	cvpA	-	-	S	-	-	-	Colicin V production protein
HILFDMDG_01819	3.75e-63	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
HILFDMDG_01820	3.62e-100	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HILFDMDG_01821	8.03e-58	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
HILFDMDG_01822	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HILFDMDG_01823	0.0	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HILFDMDG_01824	1.76e-233	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
HILFDMDG_01825	4.77e-58	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HILFDMDG_01826	3.12e-251	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HILFDMDG_01827	2.86e-244	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HILFDMDG_01828	7.5e-132	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HILFDMDG_01829	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HILFDMDG_01830	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HILFDMDG_01831	2.29e-276	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
HILFDMDG_01832	1.27e-250	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HILFDMDG_01833	4.8e-291	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
HILFDMDG_01834	1.16e-133	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HILFDMDG_01835	1.96e-194	-	-	-	S	-	-	-	Helix-turn-helix domain
HILFDMDG_01836	1.83e-315	ymfH	-	-	S	-	-	-	Peptidase M16
HILFDMDG_01837	4.8e-291	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
HILFDMDG_01838	8.15e-205	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
HILFDMDG_01839	1.02e-151	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HILFDMDG_01840	3.13e-141	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HILFDMDG_01841	1.69e-120	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
HILFDMDG_01842	1.1e-194	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
HILFDMDG_01843	8.33e-230	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
HILFDMDG_01844	2.08e-157	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
HILFDMDG_01845	7.43e-313	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HILFDMDG_01846	1.05e-293	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HILFDMDG_01847	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HILFDMDG_01848	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HILFDMDG_01849	6.92e-236	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
HILFDMDG_01850	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
HILFDMDG_01851	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HILFDMDG_01852	9.66e-291	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HILFDMDG_01853	2.48e-274	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HILFDMDG_01854	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HILFDMDG_01855	4.9e-138	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HILFDMDG_01856	0.0	gadC	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	amino acid
HILFDMDG_01857	7.61e-217	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
HILFDMDG_01858	0.0	gadC	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	amino acid
HILFDMDG_01859	0.0	gadB	4.1.1.15, 4.1.2.27	-	E	ko:K01580,ko:K01634	ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940	ko00000,ko00001,ko00002,ko01000	Belongs to the group II decarboxylase family
HILFDMDG_01860	1.12e-300	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HILFDMDG_01861	0.0	frc	2.8.3.16	-	C	ko:K07749	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HILFDMDG_01862	0.0	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
HILFDMDG_01863	3.02e-174	-	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
HILFDMDG_01864	2.41e-179	-	-	-	S	-	-	-	Membrane
HILFDMDG_01865	1.16e-97	-	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase
HILFDMDG_01866	1.97e-28	-	-	-	-	-	-	-	-
HILFDMDG_01867	2.47e-112	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HILFDMDG_01868	7.66e-309	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
HILFDMDG_01869	3.61e-61	-	-	-	-	-	-	-	-
HILFDMDG_01870	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
HILFDMDG_01871	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
HILFDMDG_01872	2.96e-100	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
HILFDMDG_01873	5.13e-60	-	-	-	-	-	-	-	-
HILFDMDG_01874	1.81e-41	-	-	-	-	-	-	-	-
HILFDMDG_01875	3.8e-63	-	-	-	-	-	-	-	-
HILFDMDG_01876	1.39e-123	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HILFDMDG_01877	2.41e-171	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
HILFDMDG_01878	3.04e-114	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
HILFDMDG_01879	1.67e-291	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
HILFDMDG_01880	2.66e-230	-	-	-	K	ko:K02525	-	ko00000,ko03000	Transcriptional regulator, LacI family
HILFDMDG_01881	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
HILFDMDG_01882	5.64e-125	-	-	-	-	-	-	-	-
HILFDMDG_01883	3.09e-35	-	-	-	-	-	-	-	-
HILFDMDG_01884	4.49e-80	asp1	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HILFDMDG_01885	3.93e-119	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
HILFDMDG_01887	5.5e-67	-	-	-	-	-	-	-	-
HILFDMDG_01888	1.5e-88	-	-	-	S	-	-	-	Belongs to the HesB IscA family
HILFDMDG_01889	5.18e-222	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
HILFDMDG_01890	2.71e-108	-	-	-	F	-	-	-	NUDIX domain
HILFDMDG_01891	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HILFDMDG_01892	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HILFDMDG_01893	1.56e-138	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HILFDMDG_01894	1.31e-210	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
HILFDMDG_01895	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HILFDMDG_01896	6.71e-208	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
HILFDMDG_01897	1.44e-180	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HILFDMDG_01898	1.71e-205	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HILFDMDG_01899	1.33e-47	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
HILFDMDG_01900	4.05e-141	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
HILFDMDG_01901	1.6e-219	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
HILFDMDG_01902	9.07e-196	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
HILFDMDG_01903	3.53e-142	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
HILFDMDG_01904	1.22e-112	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HILFDMDG_01905	2.44e-245	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HILFDMDG_01906	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HILFDMDG_01907	2.01e-286	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HILFDMDG_01908	2.61e-298	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
HILFDMDG_01909	1.6e-54	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HILFDMDG_01910	0.0	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HILFDMDG_01911	1.49e-274	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
HILFDMDG_01912	3.64e-151	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
HILFDMDG_01913	5.91e-64	-	-	-	M	-	-	-	Lysin motif
HILFDMDG_01914	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HILFDMDG_01915	4.4e-245	-	-	-	S	-	-	-	Helix-turn-helix domain
HILFDMDG_01916	1.08e-132	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HILFDMDG_01917	1.23e-163	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HILFDMDG_01918	7.8e-135	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HILFDMDG_01919	6.8e-178	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HILFDMDG_01920	2.13e-85	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HILFDMDG_01921	1.42e-212	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
HILFDMDG_01922	2.27e-216	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
HILFDMDG_01923	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
HILFDMDG_01924	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
HILFDMDG_01925	1.11e-41	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
HILFDMDG_01926	5.74e-304	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HILFDMDG_01927	1.4e-196	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HILFDMDG_01928	1.96e-163	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
HILFDMDG_01929	5.91e-279	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HILFDMDG_01930	5.12e-266	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HILFDMDG_01931	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HILFDMDG_01932	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
HILFDMDG_01933	2.14e-234	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
HILFDMDG_01934	4.65e-184	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
HILFDMDG_01935	2.1e-216	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HILFDMDG_01936	7.06e-79	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
HILFDMDG_01937	7.1e-106	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HILFDMDG_01938	6.13e-233	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
HILFDMDG_01939	2e-216	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HILFDMDG_01940	2.57e-96	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
HILFDMDG_01941	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
HILFDMDG_01942	3.59e-304	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
HILFDMDG_01943	8.77e-237	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HILFDMDG_01944	2.34e-92	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
HILFDMDG_01945	1e-31	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
HILFDMDG_01946	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HILFDMDG_01947	3e-168	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HILFDMDG_01948	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HILFDMDG_01951	8.53e-115	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HILFDMDG_01952	1.78e-57	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HILFDMDG_01953	1.81e-78	-	-	-	S	-	-	-	macrophage migration inhibitory factor
HILFDMDG_01954	1.85e-214	-	-	-	C	-	-	-	Oxidoreductase
HILFDMDG_01957	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
HILFDMDG_01958	1.18e-189	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HILFDMDG_01961	2.21e-143	-	-	-	-	-	-	-	-
HILFDMDG_01962	0.0	-	-	-	EGP	-	-	-	Major Facilitator
HILFDMDG_01963	0.0	-	-	-	P	ko:K07085	-	ko00000	Predicted Permease Membrane Region
HILFDMDG_01964	1.1e-171	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
HILFDMDG_01965	3.54e-165	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
HILFDMDG_01966	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HILFDMDG_01967	1.58e-198	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HILFDMDG_01968	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
HILFDMDG_01969	1.16e-111	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
HILFDMDG_01971	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
HILFDMDG_01972	6.15e-234	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
HILFDMDG_01973	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
HILFDMDG_01974	5.05e-171	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HILFDMDG_01975	5.36e-135	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HILFDMDG_01976	4.46e-276	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HILFDMDG_01977	3.36e-154	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HILFDMDG_01978	3.52e-173	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HILFDMDG_01979	4.28e-181	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
HILFDMDG_01980	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HILFDMDG_01981	7.17e-162	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HILFDMDG_01982	1.93e-65	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
HILFDMDG_01983	1.69e-129	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
HILFDMDG_01984	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HILFDMDG_01985	2.84e-264	yacL	-	-	S	-	-	-	domain protein
HILFDMDG_01986	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HILFDMDG_01987	8.79e-94	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HILFDMDG_01988	2.59e-175	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HILFDMDG_01989	2.18e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HILFDMDG_01990	7.11e-32	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HILFDMDG_01991	1.1e-126	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HILFDMDG_01992	1.39e-92	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HILFDMDG_01993	8.31e-158	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HILFDMDG_01994	5.57e-290	aadAT	-	-	EK	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000	Aminotransferase, class I
HILFDMDG_01996	1.2e-298	-	-	-	M	-	-	-	Glycosyl transferase family group 2
HILFDMDG_01997	2e-264	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HILFDMDG_01998	3.6e-107	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HILFDMDG_01999	2.46e-72	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HILFDMDG_02000	3.4e-64	-	-	-	-	-	-	-	-
HILFDMDG_02002	2.94e-65	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HILFDMDG_02003	9.71e-76	XK27_06915	-	-	K	ko:K10947	-	ko00000,ko03000	transcriptional regulator PadR family
HILFDMDG_02004	1.17e-121	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
HILFDMDG_02005	3.67e-176	-	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
HILFDMDG_02006	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
HILFDMDG_02007	3.81e-254	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HILFDMDG_02008	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HILFDMDG_02009	9.33e-48	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
HILFDMDG_02010	1.25e-118	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HILFDMDG_02011	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HILFDMDG_02012	5.87e-62	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HILFDMDG_02013	4.92e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HILFDMDG_02014	4.67e-52	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
HILFDMDG_02015	6.4e-149	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HILFDMDG_02016	2.83e-69	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
HILFDMDG_02017	1.44e-232	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HILFDMDG_02018	3.71e-76	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
HILFDMDG_02019	9.08e-200	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HILFDMDG_02020	1.28e-177	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
HILFDMDG_02021	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HILFDMDG_02022	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HILFDMDG_02023	8.28e-225	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HILFDMDG_02024	1.73e-246	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HILFDMDG_02025	1.13e-165	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
HILFDMDG_02026	7.13e-134	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
HILFDMDG_02027	2.37e-250	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HILFDMDG_02028	2.44e-168	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HILFDMDG_02029	1e-287	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HILFDMDG_02030	2.2e-178	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HILFDMDG_02031	2.3e-184	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
HILFDMDG_02032	4.58e-291	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HILFDMDG_02033	2.41e-232	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid