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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HKANDMEF_00001	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HKANDMEF_00002	1.02e-260	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HKANDMEF_00004	4.07e-43	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
HKANDMEF_00005	9.09e-260	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HKANDMEF_00006	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HKANDMEF_00007	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HKANDMEF_00008	5.22e-163	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HKANDMEF_00009	5.2e-98	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HKANDMEF_00010	1.36e-65	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
HKANDMEF_00011	7.5e-111	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HKANDMEF_00012	3.26e-48	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HKANDMEF_00013	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HKANDMEF_00015	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome bd terminal oxidase subunit I
HKANDMEF_00016	8.08e-229	-	-	-	C	-	-	-	Cytochrome bd terminal oxidase subunit II
HKANDMEF_00017	1.21e-48	-	-	-	-	-	-	-	-
HKANDMEF_00018	9.81e-138	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
HKANDMEF_00021	5.26e-183	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HKANDMEF_00025	4.92e-201	p40	-	-	D	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	CHAP domain
HKANDMEF_00026	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HKANDMEF_00027	1.76e-165	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKANDMEF_00028	4.12e-128	-	-	-	K	-	-	-	transcriptional regulator
HKANDMEF_00029	4.35e-197	-	-	-	G	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HKANDMEF_00030	4.92e-65	-	-	-	-	-	-	-	-
HKANDMEF_00033	0.0	ybfG	-	-	M	-	-	-	peptidoglycan-binding domain-containing protein
HKANDMEF_00034	2.08e-188	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HKANDMEF_00035	6.97e-133	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
HKANDMEF_00036	8.19e-212	-	-	-	P	-	-	-	CorA-like Mg2+ transporter protein
HKANDMEF_00037	3.29e-146	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKANDMEF_00039	2.37e-306	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HKANDMEF_00041	0.0	pepD	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HKANDMEF_00042	1.02e-144	-	-	-	S	-	-	-	Membrane
HKANDMEF_00043	4.98e-68	-	-	-	-	-	-	-	-
HKANDMEF_00045	4.32e-133	-	-	-	-	-	-	-	-
HKANDMEF_00046	2.3e-101	-	-	-	-	-	-	-	-
HKANDMEF_00047	4.97e-70	-	-	-	-	-	-	-	-
HKANDMEF_00048	1.95e-159	azlC	-	-	E	-	-	-	branched-chain amino acid
HKANDMEF_00049	1.83e-66	azlD	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
HKANDMEF_00051	2.44e-40	-	-	-	-	-	-	-	-
HKANDMEF_00052	2.25e-185	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HKANDMEF_00053	1.19e-150	eda	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	KDPG and KHG aldolase
HKANDMEF_00054	0.0	-	-	-	L	-	-	-	Transposase DDE domain
HKANDMEF_00055	7.74e-163	kdgR	-	-	K	-	-	-	FCD domain
HKANDMEF_00056	3.45e-74	ps105	-	-	-	-	-	-	-
HKANDMEF_00057	3.38e-210	-	-	-	K	-	-	-	Transcriptional activator, Rgg GadR MutR family
HKANDMEF_00058	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
HKANDMEF_00059	6.85e-310	-	-	-	EGP	-	-	-	Major Facilitator
HKANDMEF_00061	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
HKANDMEF_00062	2.34e-140	-	-	-	K	ko:K22106	-	ko00000,ko03000	Tetracycline repressor, C-terminal all-alpha domain
HKANDMEF_00064	3.93e-142	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKANDMEF_00065	3.55e-222	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HKANDMEF_00066	2.28e-136	opuCB	-	-	E	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HKANDMEF_00067	8.51e-286	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HKANDMEF_00068	0.000666	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HKANDMEF_00070	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
HKANDMEF_00071	3.61e-46	copZ	-	-	P	-	-	-	Heavy-metal-associated domain
HKANDMEF_00072	3.09e-133	dpsB	-	-	P	-	-	-	Belongs to the Dps family
HKANDMEF_00073	2.13e-150	flp	-	-	K	ko:K21562	-	ko00000,ko03000	helix_turn_helix, cAMP Regulatory protein
HKANDMEF_00074	2.39e-183	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HKANDMEF_00075	1.74e-293	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HKANDMEF_00076	6.7e-135	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
HKANDMEF_00077	7.66e-178	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
HKANDMEF_00078	1.84e-237	trpD	2.4.2.18, 4.1.3.27	-	F	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HKANDMEF_00079	1.02e-298	-	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HKANDMEF_00080	1.47e-60	-	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HKANDMEF_00081	8.8e-103	-	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKANDMEF_00082	6.16e-177	-	-	-	S	-	-	-	Domain of unknown function (DUF4918)
HKANDMEF_00083	3.34e-268	-	-	-	-	-	-	-	-
HKANDMEF_00084	0.0	-	-	-	EGP	-	-	-	Major Facilitator
HKANDMEF_00085	1.04e-139	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKANDMEF_00087	1.28e-166	-	-	-	-	-	-	-	-
HKANDMEF_00088	2.19e-289	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-type transport system involved in multi-copper enzyme maturation permease component
HKANDMEF_00089	9.92e-212	-	-	-	-	-	-	-	-
HKANDMEF_00090	1.38e-155	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HKANDMEF_00091	7.63e-85	-	-	-	S	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
HKANDMEF_00093	7.65e-61	-	-	-	M	-	-	-	Peptidoglycan-binding domain 1 protein
HKANDMEF_00094	0.0	ybfG	-	-	M	-	-	-	peptidoglycan-binding domain-containing protein
HKANDMEF_00096	5.43e-180	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HKANDMEF_00097	4.95e-215	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HKANDMEF_00098	6.4e-282	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HKANDMEF_00099	4.4e-116	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HKANDMEF_00100	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HKANDMEF_00101	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HKANDMEF_00102	4.38e-242	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HKANDMEF_00103	1.74e-252	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HKANDMEF_00104	8.46e-84	-	-	-	-	-	-	-	-
HKANDMEF_00105	1.35e-97	-	-	-	L	-	-	-	NUDIX domain
HKANDMEF_00106	4.62e-193	-	-	-	EG	-	-	-	EamA-like transporter family
HKANDMEF_00107	3.35e-125	-	-	-	S	-	-	-	Phospholipase A2
HKANDMEF_00109	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
HKANDMEF_00110	1.35e-97	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HKANDMEF_00111	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HKANDMEF_00112	2.31e-277	-	-	-	-	-	-	-	-
HKANDMEF_00114	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HKANDMEF_00115	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
HKANDMEF_00116	4.34e-75	cadC5	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
HKANDMEF_00117	0.0	-	3.6.3.6	-	P	ko:K01535	ko00190,map00190	ko00000,ko00001,ko01000	Cation transporter/ATPase, N-terminus
HKANDMEF_00118	1.78e-208	lysR5	-	-	K	-	-	-	LysR substrate binding domain
HKANDMEF_00119	3.32e-263	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HKANDMEF_00120	1.91e-46	-	-	-	S	-	-	-	Phospholipase_D-nuclease N-terminal
HKANDMEF_00121	2.26e-215	yxlF	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HKANDMEF_00122	3.78e-170	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HKANDMEF_00123	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
HKANDMEF_00124	1.45e-172	-	-	-	-	-	-	-	-
HKANDMEF_00125	4e-133	-	-	-	K	-	-	-	Bacteriophage CI repressor helix-turn-helix domain
HKANDMEF_00126	0.0	-	-	-	-	-	-	-	-
HKANDMEF_00127	4.68e-185	-	-	-	T	-	-	-	Calcineurin-like phosphoesterase superfamily domain
HKANDMEF_00128	0.0	yvdP	-	-	C	-	-	-	COG0277 FAD FMN-containing dehydrogenases
HKANDMEF_00129	0.0	-	-	-	L	-	-	-	Transposase DDE domain
HKANDMEF_00131	4.68e-53	-	-	-	-	-	-	-	-
HKANDMEF_00132	2.66e-57	-	-	-	S	-	-	-	Protein of unknown function (DUF2089)
HKANDMEF_00133	1.4e-238	yveB	-	-	I	-	-	-	PAP2 superfamily
HKANDMEF_00134	2.35e-269	mccF	-	-	V	-	-	-	LD-carboxypeptidase
HKANDMEF_00135	6.55e-57	-	-	-	-	-	-	-	-
HKANDMEF_00136	2.61e-261	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HKANDMEF_00137	2.47e-117	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Methyltransferase
HKANDMEF_00138	1.17e-245	ldhD3	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HKANDMEF_00139	1.21e-59	-	-	-	-	-	-	-	-
HKANDMEF_00140	2.74e-112	-	-	-	K	-	-	-	Transcriptional regulator
HKANDMEF_00141	1.07e-239	-	1.6.5.5	-	C	ko:K00344	-	ko00000,ko01000	alcohol dehydrogenase
HKANDMEF_00142	1.61e-72	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
HKANDMEF_00143	2.42e-72	-	-	-	S	-	-	-	Protein of unknown function (DUF1516)
HKANDMEF_00144	0.0	XK27_07275	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HKANDMEF_00145	5.52e-61	-	-	-	S	ko:K09004	-	ko00000	DsrE/DsrF-like family
HKANDMEF_00146	6.51e-247	-	-	-	L	ko:K07482	-	ko00000	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HKANDMEF_00147	1.01e-225	mhqA	-	-	E	ko:K15975	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HKANDMEF_00148	6.64e-39	-	-	-	-	-	-	-	-
HKANDMEF_00149	1.8e-135	yoaA	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HKANDMEF_00150	0.0	-	-	-	-	-	-	-	-
HKANDMEF_00152	3.46e-168	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HKANDMEF_00153	5.01e-172	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HKANDMEF_00154	2.17e-245	ynjC	-	-	S	-	-	-	Cell surface protein
HKANDMEF_00156	0.0	-	-	-	L	-	-	-	Mga helix-turn-helix domain
HKANDMEF_00157	1.45e-232	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
HKANDMEF_00158	1.1e-76	-	-	-	-	-	-	-	-
HKANDMEF_00159	0.0	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
HKANDMEF_00160	6.45e-284	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HKANDMEF_00161	2.01e-205	pphA	3.1.3.16	-	T	ko:K07313	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
HKANDMEF_00162	8.09e-180	-	-	-	L	ko:K07457	-	ko00000	Base excision DNA repair protein, HhH-GPD family
HKANDMEF_00163	8.86e-62	-	-	-	S	-	-	-	Thiamine-binding protein
HKANDMEF_00164	0.0	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
HKANDMEF_00165	4.77e-130	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKANDMEF_00166	0.0	bmr3	-	-	EGP	-	-	-	Major Facilitator
HKANDMEF_00168	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
HKANDMEF_00169	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HKANDMEF_00170	1.15e-25	-	-	-	-	-	-	-	-
HKANDMEF_00172	8.72e-105	-	-	-	S	-	-	-	NUDIX domain
HKANDMEF_00173	1.33e-276	-	-	-	S	-	-	-	nuclear-transcribed mRNA catabolic process, no-go decay
HKANDMEF_00174	0.0	fnq20	-	-	S	-	-	-	FAD-NAD(P)-binding
HKANDMEF_00175	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
HKANDMEF_00176	6.18e-150	-	-	-	-	-	-	-	-
HKANDMEF_00177	2.18e-289	-	-	-	S	ko:K06872	-	ko00000	TPM domain
HKANDMEF_00178	8.76e-178	yunE	-	-	S	ko:K07090	-	ko00000	Sulfite exporter TauE/SafE
HKANDMEF_00179	6.45e-74	ywjH	-	-	S	-	-	-	Protein of unknown function (DUF1634)
HKANDMEF_00180	1.47e-07	-	-	-	-	-	-	-	-
HKANDMEF_00181	5.12e-117	-	-	-	-	-	-	-	-
HKANDMEF_00182	4.85e-65	-	-	-	-	-	-	-	-
HKANDMEF_00183	1.63e-109	-	-	-	C	-	-	-	Flavodoxin
HKANDMEF_00184	5.54e-50	-	-	-	-	-	-	-	-
HKANDMEF_00185	2.82e-36	-	-	-	-	-	-	-	-
HKANDMEF_00186	2.86e-219	-	1.1.1.26	-	CH	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HKANDMEF_00187	2.27e-94	-	-	-	S	ko:K07006	-	ko00000	Pyridoxamine 5'-phosphate oxidase
HKANDMEF_00188	1.93e-52	-	-	-	S	-	-	-	Transglycosylase associated protein
HKANDMEF_00189	5.77e-113	-	-	-	S	-	-	-	Protein conserved in bacteria
HKANDMEF_00190	4.15e-34	-	-	-	-	-	-	-	-
HKANDMEF_00191	8.12e-90	asp23	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HKANDMEF_00192	1.97e-92	asp2	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HKANDMEF_00193	9.28e-148	-	-	-	S	-	-	-	Protein of unknown function (DUF969)
HKANDMEF_00194	1.42e-195	-	-	-	S	-	-	-	Protein of unknown function (DUF979)
HKANDMEF_00195	1.2e-154	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HKANDMEF_00196	3.05e-139	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
HKANDMEF_00197	6.67e-165	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
HKANDMEF_00198	4.01e-87	-	-	-	-	-	-	-	-
HKANDMEF_00199	3.36e-169	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
HKANDMEF_00200	6.84e-189	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HKANDMEF_00201	1.49e-177	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
HKANDMEF_00202	1.11e-201	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HKANDMEF_00203	3.26e-40	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
HKANDMEF_00204	9.76e-237	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HKANDMEF_00205	7.77e-173	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
HKANDMEF_00206	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HKANDMEF_00207	1.23e-157	-	-	-	-	-	-	-	-
HKANDMEF_00208	1.68e-156	vanR	-	-	K	-	-	-	response regulator
HKANDMEF_00209	2.81e-278	hpk31	-	-	T	-	-	-	Histidine kinase
HKANDMEF_00210	4.75e-304	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HKANDMEF_00211	1.02e-103	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HKANDMEF_00212	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HKANDMEF_00213	2.71e-182	racD	5.1.1.13	-	G	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
HKANDMEF_00214	3.48e-212	yvgN	-	-	C	-	-	-	Aldo keto reductase
HKANDMEF_00215	3.54e-187	iolR	-	-	K	ko:K06608,ko:K11534	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
HKANDMEF_00216	0.0	iolT	-	-	EGP	ko:K06609	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HKANDMEF_00217	0.0	iolA	1.2.1.18, 1.2.1.27	-	C	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HKANDMEF_00218	8.47e-201	iolB	5.3.1.30	-	G	ko:K03337	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
HKANDMEF_00219	6.58e-228	iolC	2.7.1.92	-	H	ko:K03338	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
HKANDMEF_00220	0.0	iolD	3.7.1.22	-	E	ko:K03336	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
HKANDMEF_00221	9.62e-247	-	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, NAD-binding Rossmann fold
HKANDMEF_00222	3.37e-249	iolG2	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
HKANDMEF_00223	1.27e-223	iolE	4.2.1.44	-	G	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
HKANDMEF_00224	1.4e-204	iolJ	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
HKANDMEF_00225	8.67e-88	yodA	-	-	S	-	-	-	Tautomerase enzyme
HKANDMEF_00226	3.12e-187	gntR	-	-	K	-	-	-	rpiR family
HKANDMEF_00227	1.27e-217	gntZ	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
HKANDMEF_00228	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
HKANDMEF_00229	6.55e-270	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
HKANDMEF_00230	3.01e-315	-	-	-	S	-	-	-	O-antigen ligase like membrane protein
HKANDMEF_00231	6.41e-196	-	-	-	S	-	-	-	Glycosyl transferase family 2
HKANDMEF_00232	7.56e-165	welB	-	-	S	-	-	-	Glycosyltransferase like family 2
HKANDMEF_00233	4.2e-208	-	-	-	S	-	-	-	Glycosyltransferase like family 2
HKANDMEF_00234	1.99e-192	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
HKANDMEF_00235	0.0	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HKANDMEF_00236	0.0	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
HKANDMEF_00237	1.85e-207	-	-	-	S	ko:K07011	-	ko00000	Glycosyltransferase like family 2
HKANDMEF_00238	6.33e-254	-	-	-	S	-	-	-	Protein conserved in bacteria
HKANDMEF_00239	3.74e-75	-	-	-	-	-	-	-	-
HKANDMEF_00240	1.01e-167	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HKANDMEF_00241	5.98e-173	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
HKANDMEF_00242	3.1e-213	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
HKANDMEF_00243	2.25e-207	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
HKANDMEF_00244	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
HKANDMEF_00245	4.84e-256	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HKANDMEF_00246	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HKANDMEF_00247	2.43e-103	-	-	-	T	-	-	-	Sh3 type 3 domain protein
HKANDMEF_00248	7.68e-174	glcR	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
HKANDMEF_00249	2.32e-188	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HKANDMEF_00250	1.32e-175	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
HKANDMEF_00251	2.19e-54	-	-	-	-	-	-	-	-
HKANDMEF_00252	1.26e-139	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HKANDMEF_00253	6.35e-228	draG	-	-	O	-	-	-	ADP-ribosylglycohydrolase
HKANDMEF_00254	0.0	-	-	-	S	-	-	-	ABC transporter
HKANDMEF_00255	3.54e-176	ypaC	-	-	Q	-	-	-	Methyltransferase domain
HKANDMEF_00256	5.19e-90	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
HKANDMEF_00258	3.02e-71	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HKANDMEF_00259	2.2e-176	-	-	-	S	-	-	-	Putative threonine/serine exporter
HKANDMEF_00260	2.51e-98	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HKANDMEF_00261	3.96e-274	livJ	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
HKANDMEF_00262	1.04e-191	livH	-	-	U	ko:K01997	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
HKANDMEF_00263	2.87e-11	livM	-	-	E	ko:K01997,ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
HKANDMEF_00264	2.9e-153	livM	-	-	E	ko:K01997,ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
HKANDMEF_00265	3.01e-180	livG	-	-	E	ko:K01995	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid ATP-binding cassette transporter
HKANDMEF_00266	1.16e-159	livF	-	-	E	ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
HKANDMEF_00267	7.59e-214	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HKANDMEF_00268	6.06e-308	pts14C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKANDMEF_00269	4.1e-152	-	-	-	G	-	-	-	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HKANDMEF_00270	1.01e-149	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HKANDMEF_00271	3.24e-293	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
HKANDMEF_00272	3.82e-167	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
HKANDMEF_00273	2.38e-212	p75	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
HKANDMEF_00276	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
HKANDMEF_00277	4.55e-206	-	-	-	-	-	-	-	-
HKANDMEF_00278	3.03e-158	-	-	-	-	-	-	-	-
HKANDMEF_00279	0.0	uvrB3	3.1.12.1	-	KL	ko:K07464	-	ko00000,ko01000,ko02048	DEAD_2
HKANDMEF_00280	1.73e-307	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HKANDMEF_00281	1.2e-121	-	-	-	-	-	-	-	-
HKANDMEF_00282	0.0	strH	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Gram-positive signal peptide protein, YSIRK family
HKANDMEF_00283	9.12e-249	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HKANDMEF_00284	5.43e-167	-	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
HKANDMEF_00285	9.86e-282	agaS	-	-	G	ko:K02082	-	ko00000,ko01000	SIS domain
HKANDMEF_00286	2.26e-288	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HKANDMEF_00287	0.0	bgaC	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Glycosyl hydrolases family 35
HKANDMEF_00288	5.61e-108	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HKANDMEF_00289	4.68e-206	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
HKANDMEF_00290	3.66e-187	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
HKANDMEF_00291	2.72e-85	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HKANDMEF_00292	1.23e-292	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
HKANDMEF_00293	1.01e-55	-	4.4.1.8	-	E	ko:K00842,ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HKANDMEF_00294	0.0	-	-	-	L	-	-	-	Transposase DDE domain
HKANDMEF_00295	9.35e-225	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
HKANDMEF_00296	1.33e-252	-	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HKANDMEF_00297	0.0	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKANDMEF_00298	2.96e-78	-	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HKANDMEF_00299	2.04e-68	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
HKANDMEF_00300	6.02e-242	-	-	-	E	-	-	-	M42 glutamyl aminopeptidase
HKANDMEF_00301	0.0	-	-	-	GKT	ko:K03491	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKANDMEF_00302	4.24e-310	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HKANDMEF_00303	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HKANDMEF_00304	2.16e-156	-	-	-	S	ko:K03824	-	ko00000,ko01000	Acetyltransferase (GNAT) family
HKANDMEF_00306	4.57e-123	-	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
HKANDMEF_00307	6.91e-314	-	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HKANDMEF_00308	2.8e-144	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
HKANDMEF_00309	1.76e-168	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HKANDMEF_00310	1.07e-108	thiW	-	-	S	-	-	-	Thiamine-precursor transporter protein (ThiW)
HKANDMEF_00311	6.12e-194	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HKANDMEF_00312	5.42e-141	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HKANDMEF_00313	2.31e-191	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HKANDMEF_00314	0.0	-	-	-	E	-	-	-	Amino acid permease
HKANDMEF_00315	7e-47	-	-	-	-	-	-	-	-
HKANDMEF_00316	2.08e-240	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
HKANDMEF_00317	5.41e-87	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HKANDMEF_00318	0.0	rbsA	3.6.3.17	-	G	ko:K10441	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HKANDMEF_00319	4.84e-198	rbsC	-	-	U	ko:K10440	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HKANDMEF_00320	1.71e-215	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein domain
HKANDMEF_00321	3.3e-208	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HKANDMEF_00322	3.09e-56	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
HKANDMEF_00323	0.0	pbpC	-	-	M	ko:K21467	-	ko00000,ko01011	NTF2-like N-terminal transpeptidase domain
HKANDMEF_00324	7.42e-311	-	-	-	EGP	-	-	-	Major Facilitator
HKANDMEF_00325	3.79e-96	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HKANDMEF_00326	4.65e-134	-	-	-	-	-	-	-	-
HKANDMEF_00327	4.22e-41	-	-	-	-	-	-	-	-
HKANDMEF_00328	1.49e-84	-	-	-	-	-	-	-	-
HKANDMEF_00329	4.54e-91	-	-	-	-	-	-	-	-
HKANDMEF_00330	1.28e-89	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
HKANDMEF_00331	1.29e-122	-	-	-	-	-	-	-	-
HKANDMEF_00332	1.38e-49	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HKANDMEF_00333	0.0	-	-	-	L	-	-	-	Transposase DDE domain
HKANDMEF_00334	6.45e-91	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HKANDMEF_00335	9.65e-163	-	-	-	-	-	-	-	-
HKANDMEF_00336	8.53e-139	-	-	-	-	-	-	-	-
HKANDMEF_00337	1.17e-173	-	-	-	-	-	-	-	-
HKANDMEF_00338	0.0	frdC	1.3.5.1, 1.3.5.4	-	C	ko:K00239,ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134	ko00000,ko00001,ko00002,ko01000	HI0933-like protein
HKANDMEF_00339	7.29e-267	-	-	-	GKT	-	-	-	transcriptional antiterminator
HKANDMEF_00340	1.7e-224	-	-	-	GKT	-	-	-	transcriptional antiterminator
HKANDMEF_00341	4.1e-67	-	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HKANDMEF_00342	6.84e-293	-	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HKANDMEF_00343	2.22e-93	-	-	-	-	-	-	-	-
HKANDMEF_00344	6.47e-208	-	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
HKANDMEF_00345	1.4e-152	-	-	-	S	-	-	-	Zeta toxin
HKANDMEF_00346	3.2e-203	-	-	-	K	-	-	-	Sugar-specific transcriptional regulator TrmB
HKANDMEF_00347	9.64e-191	-	-	-	S	-	-	-	Sulfite exporter TauE/SafE
HKANDMEF_00348	5.02e-230	-	4.3.1.12	-	E	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	ko00000,ko00001,ko01000	Ornithine cyclodeaminase/mu-crystallin family
HKANDMEF_00349	1.91e-191	-	3.1.1.24	-	S	ko:K01055	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Alpha/beta hydrolase family
HKANDMEF_00353	1.72e-242	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
HKANDMEF_00355	4.63e-309	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
HKANDMEF_00357	2.37e-91	-	-	-	S	ko:K07006	-	ko00000	Pyridoxamine 5'-phosphate oxidase
HKANDMEF_00358	5.11e-93	yqeB	-	-	S	-	-	-	Pyrimidine dimer DNA glycosylase
HKANDMEF_00359	2.13e-194	bla1	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase
HKANDMEF_00360	6.93e-110	-	-	-	-	-	-	-	-
HKANDMEF_00362	7.42e-230	msmR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HKANDMEF_00363	1.22e-181	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
HKANDMEF_00364	3.24e-167	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
HKANDMEF_00365	6.11e-229	-	-	-	P	-	-	-	Type I phosphodiesterase / nucleotide pyrophosphatase
HKANDMEF_00366	1.72e-242	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
HKANDMEF_00367	9.57e-14	-	-	-	P	-	-	-	Type I phosphodiesterase / nucleotide pyrophosphatase
HKANDMEF_00368	8.68e-211	pkn1	-	-	S	-	-	-	Sulfatase-modifying factor enzyme 1
HKANDMEF_00369	2.97e-170	-	-	-	S	ko:K07090	-	ko00000	Sulfite exporter TauE/SafE
HKANDMEF_00370	1.91e-253	ydeM3	-	-	C	ko:K06871	-	ko00000	Iron-sulfur cluster-binding domain
HKANDMEF_00371	4.26e-221	rihC	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
HKANDMEF_00372	7.79e-301	dcuC	-	-	C	ko:K03326	-	ko00000,ko02000	Tripartite ATP-independent periplasmic transporter, DctM component
HKANDMEF_00373	2.36e-116	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HKANDMEF_00374	2.91e-175	-	-	-	K	-	-	-	helix_turn_helix gluconate operon transcriptional repressor
HKANDMEF_00375	2.85e-205	estA	-	CE1	S	ko:K03930	-	ko00000,ko01000	Putative esterase
HKANDMEF_00376	1.23e-193	-	-	-	G	ko:K02796,ko:K17467	ko00030,ko00051,ko00520,ko01100,ko01120,ko02060,map00030,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
HKANDMEF_00377	3.94e-173	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
HKANDMEF_00378	1.12e-116	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HKANDMEF_00379	8.5e-91	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HKANDMEF_00380	0.0	-	-	-	K	ko:K19505	-	ko00000,ko03000	Sigma-54 interaction domain
HKANDMEF_00381	1.91e-303	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	Sigma-54 factor, core binding domain
HKANDMEF_00382	0.0	-	-	-	K	ko:K02538	-	ko00000,ko03000	PRD domain
HKANDMEF_00383	3.15e-103	ptsN	2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204	-	G	ko:K02768,ko:K02769,ko:K02770,ko:K02773,ko:K02806,ko:K02821,ko:K03491,ko:K11201,ko:K20112	ko00051,ko00052,ko00053,ko01100,ko01120,ko02060,map00051,map00052,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000,ko03000	phosphoenolpyruvate-dependent sugar phosphotransferase system
HKANDMEF_00384	4.44e-224	-	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
HKANDMEF_00385	8.68e-106	-	2.7.1.202	-	G	ko:K02768	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKANDMEF_00386	1.08e-63	-	2.7.1.202	-	G	ko:K02769	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HKANDMEF_00387	4.97e-220	-	-	-	G	ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	Phosphotransferase System
HKANDMEF_00388	1.29e-233	-	-	-	G	-	-	-	Domain of unknown function (DUF4432)
HKANDMEF_00389	1.4e-173	-	5.3.1.15	-	S	ko:K09988	ko00040,map00040	ko00000,ko00001,ko01000	Pfam:DUF1498
HKANDMEF_00390	0.0	xylB	2.7.1.17, 2.7.1.53	-	G	ko:K00854,ko:K00880	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the FGGY kinase family
HKANDMEF_00391	2.27e-247	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
HKANDMEF_00392	1.21e-98	-	-	-	G	ko:K11201	-	ko00000,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKANDMEF_00393	0.0	pts31BC	-	-	G	ko:K11202,ko:K11203	-	ko00000,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HKANDMEF_00394	2.7e-291	malY	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase class I and II
HKANDMEF_00395	0.0	-	-	-	G	-	-	-	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKANDMEF_00396	0.0	-	-	-	K	-	-	-	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKANDMEF_00397	8.51e-204	-	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
HKANDMEF_00398	0.0	-	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HKANDMEF_00399	1.09e-38	-	-	-	-	-	-	-	-
HKANDMEF_00400	6.37e-82	-	-	-	L	ko:K07484	-	ko00000	IS66 Orf2 like protein
HKANDMEF_00401	0.0	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
HKANDMEF_00402	2.6e-188	-	1.1.1.140	-	IQ	ko:K00068	ko00051,map00051	ko00000,ko00001,ko01000	Enoyl-(Acyl carrier protein) reductase
HKANDMEF_00403	5.33e-98	-	2.7.1.191, 2.7.1.203	-	G	ko:K02793,ko:K17464	ko00030,ko00051,ko00520,ko01100,ko01120,ko02060,map00030,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HKANDMEF_00404	5.98e-111	-	2.7.1.203	-	G	ko:K17465	ko00030,ko01120,ko02060,map00030,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HKANDMEF_00405	5.6e-170	-	-	-	G	ko:K17466	ko00030,ko01120,ko02060,map00030,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
HKANDMEF_00406	2.58e-196	-	-	-	G	ko:K02796,ko:K17467	ko00030,ko00051,ko00520,ko01100,ko01120,ko02060,map00030,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
HKANDMEF_00407	1.83e-279	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
HKANDMEF_00408	1.05e-146	dhaL	2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15	-	S	ko:K00863,ko:K05879	ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622	ko00000,ko00001,ko00002,ko01000	Dak2
HKANDMEF_00409	1.77e-237	-	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
HKANDMEF_00410	5.39e-152	hxlA	4.1.2.43	-	G	ko:K08093	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Orotidine 5'-phosphate decarboxylase / HUMPS family
HKANDMEF_00411	5.82e-130	hxlB	5.3.1.27	-	M	ko:K08094	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	sugar phosphate isomerase involved in capsule formation
HKANDMEF_00412	5.41e-171	-	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
HKANDMEF_00413	7.05e-312	-	-	-	E	ko:K19956	ko00051,map00051	ko00000,ko00001,ko01000	Alcohol dehydrogenase GroES-like domain
HKANDMEF_00414	1.13e-224	-	-	-	K	-	-	-	sugar-binding domain protein
HKANDMEF_00415	5.02e-186	srlD2	1.1.1.140	-	IQ	ko:K00068	ko00051,map00051	ko00000,ko00001,ko01000	NAD dependent epimerase/dehydratase family
HKANDMEF_00416	1.24e-89	-	2.7.1.206	-	G	ko:K02812	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HKANDMEF_00417	4.08e-112	-	2.7.1.206	-	G	ko:K02813	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HKANDMEF_00418	3.93e-184	-	-	-	U	ko:K02746,ko:K02795,ko:K02814	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
HKANDMEF_00419	4.49e-197	manZ	-	-	G	ko:K02796,ko:K02815	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
HKANDMEF_00420	2.01e-212	kbaY	4.1.2.13, 4.1.2.40	-	G	ko:K01624,ko:K08302	ko00010,ko00030,ko00051,ko00052,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
HKANDMEF_00421	0.0	sdcS	-	-	P	ko:K14445	-	ko00000,ko02000	transporter
HKANDMEF_00422	1.16e-303	-	-	-	C	-	-	-	FAD dependent oxidoreductase
HKANDMEF_00423	2.07e-204	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
HKANDMEF_00424	1.12e-205	XK27_10120	-	-	K	-	-	-	S-adenosyl-l-methionine hydroxide adenosyltransferase
HKANDMEF_00425	1.05e-127	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
HKANDMEF_00426	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HKANDMEF_00427	3.99e-192	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
HKANDMEF_00428	2.39e-28	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HKANDMEF_00429	4.98e-68	-	-	-	-	-	-	-	-
HKANDMEF_00431	0.0	-	-	-	K	-	-	-	Sigma-54 interaction domain
HKANDMEF_00432	1.17e-95	-	-	-	G	ko:K02744	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HKANDMEF_00433	2.66e-117	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HKANDMEF_00434	6.62e-197	levC	-	-	M	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
HKANDMEF_00435	7.5e-200	levD	-	-	G	ko:K02771	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
HKANDMEF_00436	4.22e-70	-	-	-	-	-	-	-	-
HKANDMEF_00438	2.94e-162	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HKANDMEF_00439	8.29e-174	-	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
HKANDMEF_00440	5.04e-147	-	4.1.2.43	-	G	ko:K08093	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Orotidine 5'-phosphate decarboxylase / HUMPS family
HKANDMEF_00441	2.35e-125	-	5.3.1.27	-	M	ko:K08094	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	SIS domain
HKANDMEF_00442	0.0	-	2.7.1.197	-	G	ko:K02798,ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKANDMEF_00443	5.75e-286	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
HKANDMEF_00444	1.27e-248	-	1.5.1.28	-	C	ko:K04940	-	ko00000,ko01000	NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain
HKANDMEF_00445	2.48e-173	yxeO	-	-	E	ko:K16960,ko:K16963	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HKANDMEF_00446	5.72e-205	-	-	-	ET	ko:K16957	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
HKANDMEF_00447	6.06e-147	ytmL	-	-	P	ko:K16958,ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKANDMEF_00448	1.32e-153	-	-	-	P	ko:K16958	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKANDMEF_00449	1.12e-304	proP	-	-	EGP	ko:K03761,ko:K03762	-	ko00000,ko02000	Sugar (and other) transporter
HKANDMEF_00451	1.33e-17	-	-	-	S	-	-	-	YvrJ protein family
HKANDMEF_00452	2e-185	-	-	-	M	-	-	-	hydrolase, family 25
HKANDMEF_00453	2.9e-171	ypiA	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HKANDMEF_00454	1.25e-148	-	-	-	C	-	-	-	Flavodoxin
HKANDMEF_00455	6.23e-113	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKANDMEF_00456	5.69e-238	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HKANDMEF_00457	6.07e-155	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKANDMEF_00458	3.74e-53	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HKANDMEF_00459	9.99e-86	-	-	-	S	-	-	-	Phage derived protein Gp49-like (DUF891)
HKANDMEF_00460	0.0	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
HKANDMEF_00461	2.62e-194	-	-	-	S	-	-	-	hydrolase
HKANDMEF_00462	6.3e-60	-	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	Bacterial toxin of type II toxin-antitoxin system, YafQ
HKANDMEF_00463	1.15e-237	-	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
HKANDMEF_00464	1.48e-109	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HKANDMEF_00465	2.18e-177	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
HKANDMEF_00466	7.9e-196	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
HKANDMEF_00467	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
HKANDMEF_00468	1.51e-90	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HKANDMEF_00469	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HKANDMEF_00470	1.18e-157	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HKANDMEF_00471	1.94e-248	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HKANDMEF_00472	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
HKANDMEF_00474	0.0	pip	-	-	V	ko:K01421	-	ko00000	domain protein
HKANDMEF_00475	1.91e-201	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HKANDMEF_00476	3.38e-252	-	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
HKANDMEF_00477	4.99e-105	-	-	-	-	-	-	-	-
HKANDMEF_00478	0.0	l1n	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
HKANDMEF_00479	7.24e-23	-	-	-	-	-	-	-	-
HKANDMEF_00480	2.11e-132	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKANDMEF_00481	2.1e-78	dhaM	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	PTS system fructose IIA component
HKANDMEF_00482	4.95e-134	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
HKANDMEF_00483	1.03e-242	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
HKANDMEF_00484	1.05e-101	-	-	-	O	-	-	-	OsmC-like protein
HKANDMEF_00485	0.0	-	-	-	L	-	-	-	Exonuclease
HKANDMEF_00486	5.14e-65	yczG	-	-	K	-	-	-	Helix-turn-helix domain
HKANDMEF_00487	4.02e-262	yceJ	-	-	EGP	ko:K08221	-	ko00000,ko02000	transporter
HKANDMEF_00488	2.07e-140	ydfF	-	-	K	-	-	-	Transcriptional
HKANDMEF_00489	6.8e-140	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
HKANDMEF_00490	2.65e-215	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
HKANDMEF_00491	0.0	cidC	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HKANDMEF_00493	1.22e-249	pbpE	-	-	V	-	-	-	Beta-lactamase
HKANDMEF_00494	1.35e-186	-	-	-	H	-	-	-	Protein of unknown function (DUF1698)
HKANDMEF_00495	1.15e-183	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
HKANDMEF_00496	0.0	-	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	Glutamine synthetase, catalytic domain
HKANDMEF_00497	6.16e-285	-	-	-	S	ko:K07045	-	ko00000	Amidohydrolase
HKANDMEF_00498	0.0	-	-	-	E	-	-	-	Amino acid permease
HKANDMEF_00499	1.68e-98	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HKANDMEF_00500	9.58e-211	-	-	-	S	-	-	-	reductase
HKANDMEF_00501	1.5e-256	qor	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HKANDMEF_00502	4.55e-76	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HKANDMEF_00503	1.68e-124	-	-	-	-	-	-	-	-
HKANDMEF_00504	0.0	-	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HKANDMEF_00505	1.54e-75	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
HKANDMEF_00506	3.96e-293	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKANDMEF_00507	4.8e-66	licB2	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HKANDMEF_00508	0.0	-	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
HKANDMEF_00509	7.9e-136	tnpR1	-	-	L	-	-	-	Resolvase, N terminal domain
HKANDMEF_00510	0.0	yvcC	-	-	M	-	-	-	Cna protein B-type domain
HKANDMEF_00511	8.54e-213	yvcC	-	-	M	-	-	-	Cna protein B-type domain
HKANDMEF_00512	8.63e-164	-	-	-	M	-	-	-	domain protein
HKANDMEF_00513	1.25e-236	-	-	-	M	-	-	-	LPXTG cell wall anchor motif
HKANDMEF_00514	3.16e-258	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
HKANDMEF_00515	1.05e-167	XK27_12140	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HKANDMEF_00516	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HKANDMEF_00517	9.4e-165	-	-	-	K	ko:K20488	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
HKANDMEF_00518	3.6e-253	-	2.7.13.3	-	T	ko:K20487	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HKANDMEF_00520	9.72e-182	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
HKANDMEF_00521	2.77e-271	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
HKANDMEF_00522	2.15e-122	-	-	-	-	-	-	-	-
HKANDMEF_00523	0.0	prtP	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HKANDMEF_00524	0.0	prtP	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HKANDMEF_00525	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
HKANDMEF_00526	0.0	ycaM	-	-	E	-	-	-	amino acid
HKANDMEF_00527	5.77e-118	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
HKANDMEF_00528	8.19e-212	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
HKANDMEF_00529	8.24e-143	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
HKANDMEF_00530	2.09e-115	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
HKANDMEF_00531	2.15e-44	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
HKANDMEF_00532	1.53e-211	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HKANDMEF_00533	2.21e-275	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HKANDMEF_00534	3.63e-216	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HKANDMEF_00535	1.65e-207	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
HKANDMEF_00536	2.2e-222	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HKANDMEF_00537	2.14e-24	-	-	-	-	-	-	-	-
HKANDMEF_00539	5.52e-286	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HKANDMEF_00544	4.87e-173	-	-	-	-	-	-	-	-
HKANDMEF_00545	2.33e-25	-	-	-	E	-	-	-	Zn peptidase
HKANDMEF_00546	1.51e-80	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HKANDMEF_00549	4.03e-202	ps305	-	-	S	-	-	-	Protein of unknown function (Hypoth_ymh)
HKANDMEF_00550	2.23e-179	-	-	-	S	-	-	-	ORF6N domain
HKANDMEF_00552	1.66e-59	-	-	-	S	-	-	-	Domain of unknown function (DUF1883)
HKANDMEF_00558	7.76e-181	-	-	-	L	-	-	-	Helix-turn-helix domain
HKANDMEF_00559	5.09e-199	pi346	-	-	L	ko:K02315	-	ko00000,ko03032	IstB-like ATP binding protein
HKANDMEF_00561	3.84e-94	-	-	-	-	-	-	-	-
HKANDMEF_00562	6.1e-172	-	-	-	-	-	-	-	-
HKANDMEF_00565	4.76e-105	-	-	-	-	-	-	-	-
HKANDMEF_00567	1.21e-242	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
HKANDMEF_00568	0.000324	-	-	-	S	-	-	-	CsbD-like
HKANDMEF_00570	4.05e-206	-	-	-	-	-	-	-	-
HKANDMEF_00571	3.44e-64	-	-	-	-	-	-	-	-
HKANDMEF_00572	8.29e-74	-	-	-	-	-	-	-	-
HKANDMEF_00573	2.11e-69	-	-	-	L	ko:K07483	-	ko00000	4.5 Transposon and IS
HKANDMEF_00574	2.5e-174	-	-	-	L	-	-	-	Helix-turn-helix domain
HKANDMEF_00575	2.46e-215	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HKANDMEF_00576	1.25e-200	-	-	-	L	ko:K07497	-	ko00000	4.5 Transposon and IS
HKANDMEF_00581	6.78e-42	-	-	-	-	-	-	-	-
HKANDMEF_00582	1.71e-283	-	-	-	-	-	-	-	-
HKANDMEF_00583	5.11e-312	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
HKANDMEF_00586	0.0	-	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	TraM recognition site of TraD and TraG
HKANDMEF_00587	0.0	-	-	-	S	-	-	-	domain, Protein
HKANDMEF_00589	1.77e-137	-	-	-	-	-	-	-	-
HKANDMEF_00590	0.0	-	-	-	S	-	-	-	COG0433 Predicted ATPase
HKANDMEF_00591	2.45e-244	-	-	-	M	ko:K21471,ko:K21472	-	ko00000,ko01000,ko01002,ko01011	cysteine-type peptidase activity
HKANDMEF_00596	0.000934	-	-	-	S	-	-	-	Ribbon-helix-helix protein, copG family
HKANDMEF_00598	4.83e-295	-	-	-	S	-	-	-	COG0790 FOG TPR repeat, SEL1 subfamily
HKANDMEF_00600	0.0	-	-	-	L	-	-	-	Protein of unknown function (DUF3991)
HKANDMEF_00602	1.05e-88	-	-	-	-	-	-	-	-
HKANDMEF_00603	4.79e-21	-	-	-	-	-	-	-	-
HKANDMEF_00604	3.24e-64	-	-	-	-	-	-	-	-
HKANDMEF_00605	3.16e-23	-	-	-	-	-	-	-	-
HKANDMEF_00607	1.72e-103	-	-	-	-	-	-	-	-
HKANDMEF_00608	1.15e-200	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
HKANDMEF_00610	1.56e-154	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
HKANDMEF_00612	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HKANDMEF_00613	1.69e-107	-	-	-	L	-	-	-	Transposase DDE domain
HKANDMEF_00614	1.51e-77	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
HKANDMEF_00615	7.52e-87	repA	-	-	S	-	-	-	Replication initiator protein A
HKANDMEF_00616	4.59e-58	-	-	-	-	-	-	-	-
HKANDMEF_00617	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HKANDMEF_00618	5.26e-164	tnp1216	-	-	L	ko:K07498	-	ko00000	DDE domain
HKANDMEF_00619	1.16e-248	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HKANDMEF_00620	1.19e-107	-	-	-	L	-	-	-	Transposase DDE domain
HKANDMEF_00621	1.51e-77	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
HKANDMEF_00622	1.12e-150	tnp1216	-	-	L	ko:K07498	-	ko00000	DDE domain
HKANDMEF_00623	3.25e-224	-	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HKANDMEF_00624	5.86e-190	-	-	-	G	-	-	-	PTS system mannose/fructose/sorbose family IID component
HKANDMEF_00625	1.65e-184	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
HKANDMEF_00626	2.1e-114	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HKANDMEF_00627	5.68e-91	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HKANDMEF_00628	2.3e-169	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HKANDMEF_00629	9.41e-176	frlR1	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
HKANDMEF_00631	3.33e-133	tnpR	-	-	L	-	-	-	Resolvase, N terminal domain
HKANDMEF_00632	3.3e-315	xylP	-	-	G	-	-	-	MFS/sugar transport protein
HKANDMEF_00633	7.69e-134	-	-	-	-	-	-	-	-
HKANDMEF_00634	8.93e-47	-	-	-	-	-	-	-	-
HKANDMEF_00635	8.37e-108	-	-	-	L	-	-	-	Transposase DDE domain
HKANDMEF_00636	1.51e-77	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
HKANDMEF_00637	5.96e-28	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
HKANDMEF_00638	1.04e-187	is18	-	-	L	-	-	-	Integrase core domain
HKANDMEF_00639	2.78e-25	-	-	-	L	ko:K07483	-	ko00000	transposase activity
HKANDMEF_00640	5.16e-210	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HKANDMEF_00641	2.73e-140	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HKANDMEF_00642	2.99e-309	XK27_09615	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
HKANDMEF_00643	2.78e-25	-	-	-	L	ko:K07483	-	ko00000	transposase activity
HKANDMEF_00644	1.04e-187	is18	-	-	L	-	-	-	Integrase core domain
HKANDMEF_00645	0.0	dld	1.1.5.12	-	C	ko:K03777	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	D-lactate dehydrogenase, membrane binding
HKANDMEF_00646	3.8e-39	-	-	-	-	-	-	-	-
HKANDMEF_00647	6.37e-82	-	-	-	L	ko:K07484	-	ko00000	IS66 Orf2 like protein
HKANDMEF_00648	0.0	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
HKANDMEF_00649	7.23e-244	ysdE	-	-	P	-	-	-	Citrate transporter
HKANDMEF_00650	3.35e-84	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
HKANDMEF_00651	8.39e-21	-	-	-	L	ko:K07483	-	ko00000	Transposase and inactivated derivatives
HKANDMEF_00652	7.48e-197	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HKANDMEF_00653	4.68e-189	-	-	-	-	-	-	-	-
HKANDMEF_00654	1.38e-274	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HKANDMEF_00655	6.84e-186	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
HKANDMEF_00656	8.58e-159	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HKANDMEF_00657	6.3e-42	-	-	-	-	-	-	-	-
HKANDMEF_00658	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HKANDMEF_00659	1.14e-151	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HKANDMEF_00660	2.1e-226	-	-	-	S	-	-	-	Cell surface protein
HKANDMEF_00661	1.78e-58	-	-	-	-	-	-	-	-
HKANDMEF_00662	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
HKANDMEF_00663	1.66e-154	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HKANDMEF_00664	4.82e-78	-	-	-	-	-	-	-	-
HKANDMEF_00665	3.82e-142	-	-	-	N	-	-	-	WxL domain surface cell wall-binding
HKANDMEF_00666	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
HKANDMEF_00667	4.19e-226	yicL	-	-	EG	-	-	-	EamA-like transporter family
HKANDMEF_00668	0.0	-	-	-	-	-	-	-	-
HKANDMEF_00669	3.03e-186	CcmA5	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HKANDMEF_00670	4.07e-114	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
HKANDMEF_00671	1.83e-192	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
HKANDMEF_00672	7.88e-211	metF	1.5.1.20	-	C	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Methylenetetrahydrofolate reductase
HKANDMEF_00673	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HKANDMEF_00674	0.0	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HKANDMEF_00675	0.0	-	-	-	V	ko:K06147,ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HKANDMEF_00676	3.34e-286	oxlT	-	-	P	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
HKANDMEF_00677	5.43e-167	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
HKANDMEF_00678	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HKANDMEF_00679	0.0	treB	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HKANDMEF_00680	2.25e-285	sstT	-	-	U	ko:K07862	-	ko00000,ko02000	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
HKANDMEF_00681	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
HKANDMEF_00682	3.94e-222	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	lactate/malate dehydrogenase, alpha/beta C-terminal domain
HKANDMEF_00683	0.0	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HKANDMEF_00684	3.08e-43	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
HKANDMEF_00685	1.54e-91	-	-	-	-	-	-	-	-
HKANDMEF_00686	1.37e-99	-	-	-	O	-	-	-	OsmC-like protein
HKANDMEF_00687	0.0	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
HKANDMEF_00688	2.73e-147	ylbE	-	-	GM	-	-	-	NAD(P)H-binding
HKANDMEF_00690	4.04e-204	-	-	-	S	-	-	-	Aldo/keto reductase family
HKANDMEF_00691	9.04e-317	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
HKANDMEF_00692	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF3800)
HKANDMEF_00693	0.0	nhaK	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HKANDMEF_00694	2.72e-78	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
HKANDMEF_00695	2.95e-96	-	-	-	K	-	-	-	LytTr DNA-binding domain
HKANDMEF_00696	3.79e-192	-	-	-	V	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
HKANDMEF_00697	6.73e-211	-	-	-	V	ko:K01990,ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HKANDMEF_00698	6.41e-190	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HKANDMEF_00699	3.43e-162	cah	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	Eukaryotic-type carbonic anhydrase
HKANDMEF_00700	1.06e-69	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
HKANDMEF_00701	1.35e-208	-	-	-	C	-	-	-	nadph quinone reductase
HKANDMEF_00702	3.8e-316	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
HKANDMEF_00703	2.05e-229	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
HKANDMEF_00704	2.22e-154	yqgG	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
HKANDMEF_00705	4.52e-160	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
HKANDMEF_00706	0.000673	-	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Psort location CytoplasmicMembrane, score
HKANDMEF_00707	1.62e-159	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	proteolysis
HKANDMEF_00708	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
HKANDMEF_00709	0.0	-	-	-	L	-	-	-	ATPase domain of DNA mismatch repair MUTS family
HKANDMEF_00710	3.79e-147	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
HKANDMEF_00711	1.9e-170	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HKANDMEF_00712	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	C-terminal domain of alpha-glycerophosphate oxidase
HKANDMEF_00713	3.83e-86	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	C-terminal domain of alpha-glycerophosphate oxidase
HKANDMEF_00714	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HKANDMEF_00715	3.06e-182	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HKANDMEF_00716	7.26e-208	lacT	-	-	K	ko:K02531	-	ko00000,ko03000	PRD domain
HKANDMEF_00717	0.0	lacE	2.7.1.207	-	G	ko:K02787,ko:K02788	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase system, EIIC
HKANDMEF_00718	0.0	lacG	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HKANDMEF_00719	2.65e-67	lacF	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
HKANDMEF_00720	2.83e-283	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HKANDMEF_00721	4.24e-247	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HKANDMEF_00722	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
HKANDMEF_00723	1.02e-219	msmR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HKANDMEF_00724	8.63e-254	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HKANDMEF_00727	2.36e-111	-	2.7.1.204	-	G	ko:K20112	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKANDMEF_00728	2.68e-67	-	2.7.1.204	-	G	ko:K20113	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HKANDMEF_00729	0.0	gatC	-	-	G	ko:K20114	ko02060,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HKANDMEF_00730	9.83e-37	-	-	-	-	-	-	-	-
HKANDMEF_00731	1.98e-163	-	-	-	S	-	-	-	Domain of unknown function (DUF4867)
HKANDMEF_00732	4.29e-226	lacC	2.7.1.144	-	H	ko:K00917	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
HKANDMEF_00733	1.78e-240	lacD	4.1.2.40	-	G	ko:K01635	ko00052,ko01100,ko02024,map00052,map01100,map02024	ko00000,ko00001,ko01000	Belongs to the aldolase LacD family
HKANDMEF_00734	4.53e-122	lacB	5.3.1.26	-	G	ko:K01819	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	Ribose/Galactose Isomerase
HKANDMEF_00735	7.23e-96	lacA	5.3.1.26	-	G	ko:K01819	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	Ribose/Galactose Isomerase
HKANDMEF_00736	4.13e-181	-	-	-	K	ko:K02530	-	ko00000,ko03000	DeoR C terminal sensor domain
HKANDMEF_00737	3.73e-150	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant
HKANDMEF_00738	3.37e-272	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HKANDMEF_00739	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
HKANDMEF_00740	6.8e-21	-	-	-	-	-	-	-	-
HKANDMEF_00741	7.42e-112	hsp1	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HKANDMEF_00743	4.59e-272	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific adenine glycosylase
HKANDMEF_00744	1.91e-192	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HKANDMEF_00745	1.06e-156	yrkL	-	-	S	-	-	-	Flavodoxin-like fold
HKANDMEF_00747	1.83e-113	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
HKANDMEF_00748	1.92e-153	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HKANDMEF_00749	9.5e-199	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HKANDMEF_00750	3.35e-252	-	-	-	-	-	-	-	-
HKANDMEF_00752	1.39e-149	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
HKANDMEF_00753	0.0	bglB	3.2.1.21, 3.2.1.52	GH3	G	ko:K01207,ko:K05349	ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501	ko00000,ko00001,ko00002,ko01000	hydrolase, family 3
HKANDMEF_00754	6.45e-215	XK27_00670	-	-	S	ko:K01989,ko:K05832	-	ko00000,ko00002,ko02000	ABC transporter substrate binding protein
HKANDMEF_00755	1.77e-214	XK27_00670	-	-	S	ko:K01989,ko:K05832	-	ko00000,ko00002,ko02000	ABC transporter
HKANDMEF_00756	6.83e-208	WQ51_06230	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HKANDMEF_00757	2.89e-181	-	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKANDMEF_00758	3.01e-225	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
HKANDMEF_00759	0.0	pacL3	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
HKANDMEF_00760	8.07e-233	ykcC	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	Glycosyl transferase family 2
HKANDMEF_00761	0.0	ykcB	-	-	M	-	-	-	Dolichyl-phosphate-mannose-protein mannosyltransferase
HKANDMEF_00762	1.53e-93	-	-	-	S	-	-	-	GtrA-like protein
HKANDMEF_00763	3.91e-159	ciaR	-	-	K	ko:K14983	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	cheY-homologous receiver domain
HKANDMEF_00764	3.66e-310	ciaH	2.7.13.3	-	T	ko:K14982	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
HKANDMEF_00765	2.42e-88	-	-	-	S	-	-	-	Belongs to the HesB IscA family
HKANDMEF_00766	0.0	-	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
HKANDMEF_00767	1.12e-208	-	-	-	S	-	-	-	KR domain
HKANDMEF_00768	1.71e-205	adc	4.1.1.4	-	Q	ko:K01574	ko00072,ko00640,ko01100,map00072,map00640,map01100	ko00000,ko00001,ko00002,ko01000	Acetoacetate decarboxylase (ADC)
HKANDMEF_00769	1.77e-158	ydgI	-	-	C	-	-	-	Nitroreductase family
HKANDMEF_00770	3.19e-263	lldD	1.13.12.4	-	C	ko:K00467	ko00620,map00620	ko00000,ko00001,ko01000	IMP dehydrogenase / GMP reductase domain
HKANDMEF_00773	5.8e-248	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
HKANDMEF_00774	1.17e-77	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
HKANDMEF_00775	1.14e-63	ygbF	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
HKANDMEF_00776	4.91e-55	-	-	-	-	-	-	-	-
HKANDMEF_00777	2.1e-247	-	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HKANDMEF_00778	2.78e-73	-	-	-	-	-	-	-	-
HKANDMEF_00779	1.79e-104	-	-	-	-	-	-	-	-
HKANDMEF_00780	5.77e-267	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
HKANDMEF_00781	1.58e-33	-	-	-	-	-	-	-	-
HKANDMEF_00782	9.86e-146	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HKANDMEF_00783	4.2e-65	-	-	-	-	-	-	-	-
HKANDMEF_00784	5.96e-214	mleP2	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
HKANDMEF_00785	8.76e-82	ywrF	-	-	S	-	-	-	Flavin reductase like domain
HKANDMEF_00786	9.67e-91	-	-	-	-	-	-	-	-
HKANDMEF_00787	6.56e-131	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HKANDMEF_00788	1.7e-81	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
HKANDMEF_00789	2.2e-223	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HKANDMEF_00790	3.19e-206	mleR	-	-	K	-	-	-	LysR family
HKANDMEF_00791	0.0	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
HKANDMEF_00792	3.58e-217	mleP	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
HKANDMEF_00793	8.23e-117	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HKANDMEF_00794	2.28e-113	-	-	-	C	-	-	-	FMN binding
HKANDMEF_00795	1.32e-223	-	-	-	K	ko:K20373,ko:K20374	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix XRE-family like proteins
HKANDMEF_00796	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
HKANDMEF_00797	0.0	pepF	-	-	E	-	-	-	Oligopeptidase F
HKANDMEF_00798	9.47e-79	-	-	-	-	-	-	-	-
HKANDMEF_00799	3.81e-170	-	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HKANDMEF_00800	4.06e-107	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
HKANDMEF_00801	0.0	yfgQ	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
HKANDMEF_00802	6.63e-232	-	3.4.11.5	-	I	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	carboxylic ester hydrolase activity
HKANDMEF_00803	1.69e-58	-	-	-	-	-	-	-	-
HKANDMEF_00804	4.89e-122	-	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HKANDMEF_00805	1.38e-256	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HKANDMEF_00806	9.07e-158	XK27_05175	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	haloacid dehalogenase-like hydrolase
HKANDMEF_00807	2.24e-101	-	-	-	K	-	-	-	Transcriptional regulator
HKANDMEF_00808	2.4e-231	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
HKANDMEF_00809	3.28e-110	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
HKANDMEF_00810	4.36e-200	dkgB	-	-	S	-	-	-	reductase
HKANDMEF_00811	4.98e-203	-	-	-	-	-	-	-	-
HKANDMEF_00812	6.16e-199	-	-	-	S	-	-	-	Alpha beta hydrolase
HKANDMEF_00813	1.29e-150	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
HKANDMEF_00814	4.49e-97	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
HKANDMEF_00815	4.17e-284	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
HKANDMEF_00816	1.69e-112	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HKANDMEF_00817	1.3e-136	yjbF	-	-	S	-	-	-	SNARE associated Golgi protein
HKANDMEF_00818	2.95e-133	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HKANDMEF_00819	1.59e-241	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HKANDMEF_00820	1.11e-264	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HKANDMEF_00821	1.71e-289	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HKANDMEF_00822	4.49e-88	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HKANDMEF_00823	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
HKANDMEF_00824	2.06e-150	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	Helix-turn-helix diphteria tox regulatory element
HKANDMEF_00825	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HKANDMEF_00826	1.25e-264	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HKANDMEF_00827	1.13e-307	ytoI	-	-	K	-	-	-	DRTGG domain
HKANDMEF_00828	3.03e-229	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
HKANDMEF_00829	0.0	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HKANDMEF_00830	2.29e-225	-	-	-	-	-	-	-	-
HKANDMEF_00831	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HKANDMEF_00833	4.89e-58	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
HKANDMEF_00834	2.67e-96	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HKANDMEF_00835	1.3e-69	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
HKANDMEF_00836	2.84e-48	-	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HKANDMEF_00837	1.89e-119	cvpA	-	-	S	-	-	-	Colicin V production protein
HKANDMEF_00838	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HKANDMEF_00839	3.64e-70	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HKANDMEF_00840	1.04e-27	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
HKANDMEF_00841	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKANDMEF_00842	9.86e-304	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
HKANDMEF_00843	6.97e-49	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKANDMEF_00844	2.04e-312	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HKANDMEF_00845	2.02e-112	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
HKANDMEF_00846	0.0	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HKANDMEF_00847	1.15e-125	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
HKANDMEF_00848	1.9e-175	gla	-	-	U	ko:K02440	-	ko00000,ko02000	Major intrinsic protein
HKANDMEF_00849	6.56e-112	ykuL	-	-	S	-	-	-	CBS domain
HKANDMEF_00850	3.55e-203	-	-	-	S	ko:K08974	-	ko00000	Domain of unknown function (DUF368)
HKANDMEF_00851	6.86e-198	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
HKANDMEF_00852	1.49e-46	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HKANDMEF_00853	1.69e-114	ytxH	-	-	S	-	-	-	YtxH-like protein
HKANDMEF_00854	7.49e-117	yrxA	-	-	S	ko:K07105	-	ko00000	3H domain
HKANDMEF_00855	3.25e-276	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HKANDMEF_00856	3.03e-232	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
HKANDMEF_00857	3.35e-247	-	-	-	L	ko:K07482	-	ko00000	Helix-turn-helix domain
HKANDMEF_00858	0.0	pbp1B	2.4.1.129	GT51	M	ko:K03693,ko:K12551	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Penicillin binding protein transpeptidase domain
HKANDMEF_00859	1.78e-240	pbp1B	2.4.1.129	GT51	M	ko:K03693,ko:K12551	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Transglycosylase
HKANDMEF_00860	1.06e-163	yfnB	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	HAD-hyrolase-like
HKANDMEF_00861	5.87e-177	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HKANDMEF_00862	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
HKANDMEF_00863	0.0	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
HKANDMEF_00864	5.84e-51	-	-	-	-	-	-	-	-
HKANDMEF_00865	1.46e-241	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
HKANDMEF_00866	5.42e-150	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
HKANDMEF_00867	2.58e-148	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HKANDMEF_00868	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HKANDMEF_00869	6.42e-154	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
HKANDMEF_00870	1.34e-186	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HKANDMEF_00871	6.43e-146	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
HKANDMEF_00872	1.83e-150	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
HKANDMEF_00873	2.26e-115	pgpA	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Phosphatidylglycerophosphatase A
HKANDMEF_00874	2.84e-239	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
HKANDMEF_00875	4.42e-142	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HKANDMEF_00876	1.17e-82	yugI	-	-	J	ko:K07570	-	ko00000	general stress protein
HKANDMEF_00877	5.19e-90	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
HKANDMEF_00904	1.09e-38	-	-	-	-	-	-	-	-
HKANDMEF_00905	6.37e-82	-	-	-	L	ko:K07484	-	ko00000	IS66 Orf2 like protein
HKANDMEF_00906	0.0	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
HKANDMEF_00907	8.3e-123	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	DNA-templated transcription, initiation
HKANDMEF_00908	0.0	ybeC	-	-	E	-	-	-	amino acid
HKANDMEF_00910	1.09e-294	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HKANDMEF_00911	1.13e-252	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HKANDMEF_00912	1.58e-220	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HKANDMEF_00914	1.63e-279	araT	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HKANDMEF_00915	1.52e-57	ykuJ	-	-	S	-	-	-	Protein of unknown function (DUF1797)
HKANDMEF_00916	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HKANDMEF_00917	8.92e-105	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
HKANDMEF_00918	5.19e-90	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
HKANDMEF_00923	3.98e-91	-	-	-	-	-	-	-	-
HKANDMEF_00924	7.89e-268	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HKANDMEF_00925	0.0	mdr	-	-	EGP	-	-	-	Major Facilitator
HKANDMEF_00926	2.92e-108	-	-	-	K	-	-	-	MerR HTH family regulatory protein
HKANDMEF_00927	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HKANDMEF_00928	6.46e-156	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
HKANDMEF_00929	1.89e-157	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
HKANDMEF_00930	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
HKANDMEF_00931	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HKANDMEF_00932	2.3e-167	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HKANDMEF_00933	9.15e-45	yhcC	-	-	S	ko:K07069	-	ko00000	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
HKANDMEF_00934	3.37e-183	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HKANDMEF_00935	4.57e-124	-	-	-	F	-	-	-	NUDIX domain
HKANDMEF_00937	6.11e-278	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HKANDMEF_00938	1.64e-263	-	-	-	V	-	-	-	Abi-like protein
HKANDMEF_00939	1.68e-94	-	-	-	-	-	-	-	-
HKANDMEF_00940	4.14e-15	-	-	-	-	-	-	-	-
HKANDMEF_00941	1.09e-23	-	-	-	-	-	-	-	-
HKANDMEF_00943	0.000185	-	-	-	K	-	-	-	sequence-specific DNA binding
HKANDMEF_00945	1.01e-163	-	-	-	K	-	-	-	Transcriptional regulator
HKANDMEF_00947	3.74e-52	-	-	-	S	-	-	-	Domain of unknown function (DUF771)
HKANDMEF_00950	4.78e-217	yqaJ	-	-	L	-	-	-	YqaJ-like viral recombinase domain
HKANDMEF_00952	1.65e-210	recT	-	-	L	ko:K07455	-	ko00000,ko03400	RecT family
HKANDMEF_00953	2.43e-49	-	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
HKANDMEF_00954	1.64e-178	-	-	-	L	-	-	-	Transcriptional regulator
HKANDMEF_00955	1.57e-197	pi346	-	-	L	ko:K02315	-	ko00000,ko03032	IstB-like ATP binding protein
HKANDMEF_00957	2.14e-58	-	-	-	-	-	-	-	-
HKANDMEF_00959	7.92e-135	-	-	-	S	-	-	-	HNH endonuclease
HKANDMEF_00960	2.31e-97	rusA	-	-	L	-	-	-	Endodeoxyribonuclease RusA
HKANDMEF_00961	2.83e-53	-	-	-	-	-	-	-	-
HKANDMEF_00963	1.93e-105	-	-	-	-	-	-	-	-
HKANDMEF_00964	1.57e-91	-	-	-	V	-	-	-	HNH endonuclease
HKANDMEF_00965	1.23e-81	-	-	-	-	-	-	-	-
HKANDMEF_00966	0.0	-	-	-	S	-	-	-	overlaps another CDS with the same product name
HKANDMEF_00967	1.45e-299	-	-	-	S	-	-	-	Phage portal protein
HKANDMEF_00968	2.39e-164	clpP	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
HKANDMEF_00969	1.66e-288	-	-	-	S	-	-	-	Phage capsid family
HKANDMEF_00971	9.08e-71	-	-	-	-	-	-	-	-
HKANDMEF_00972	3.92e-76	-	-	-	S	-	-	-	Phage head-tail joining protein
HKANDMEF_00973	1.28e-75	-	-	-	-	-	-	-	-
HKANDMEF_00974	9.07e-89	-	-	-	-	-	-	-	-
HKANDMEF_00975	5.7e-153	-	-	-	-	-	-	-	-
HKANDMEF_00976	1.73e-81	-	-	-	-	-	-	-	-
HKANDMEF_00977	0.0	-	-	-	D	-	-	-	Phage tail tape measure protein
HKANDMEF_00978	1.5e-165	-	-	-	S	-	-	-	phage tail
HKANDMEF_00979	0.0	-	-	-	LM	-	-	-	gp58-like protein
HKANDMEF_00980	2.91e-94	-	-	-	-	-	-	-	-
HKANDMEF_00981	2.21e-51	-	-	-	-	-	-	-	-
HKANDMEF_00982	4.88e-59	-	-	-	-	-	-	-	-
HKANDMEF_00983	2.93e-75	hol	-	-	S	-	-	-	Bacteriophage holin
HKANDMEF_00985	3.23e-252	-	-	-	M	-	-	-	Bacteriophage peptidoglycan hydrolase
HKANDMEF_00986	0.0	tagE2	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HKANDMEF_00987	0.0	tagE3	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HKANDMEF_00988	9.78e-112	gpo	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
HKANDMEF_00991	7.73e-299	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
HKANDMEF_00992	2.27e-247	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
HKANDMEF_00993	0.0	cpdA	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HKANDMEF_00994	5.05e-52	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
HKANDMEF_00995	1.12e-311	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
HKANDMEF_00996	4.22e-273	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
HKANDMEF_00997	1.15e-150	yjbH	-	-	Q	-	-	-	Thioredoxin
HKANDMEF_00998	1.79e-138	-	-	-	S	-	-	-	CYTH
HKANDMEF_00999	1.19e-158	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
HKANDMEF_01000	1.05e-193	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HKANDMEF_01001	1.22e-219	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HKANDMEF_01002	4.86e-259	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HKANDMEF_01003	2.24e-148	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
HKANDMEF_01004	2.39e-187	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HKANDMEF_01005	2.39e-256	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
HKANDMEF_01006	3.87e-80	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
HKANDMEF_01007	4.12e-56	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HKANDMEF_01008	2.45e-245	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HKANDMEF_01009	1.94e-219	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HKANDMEF_01010	1.46e-201	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
HKANDMEF_01011	3.21e-125	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HKANDMEF_01012	4.04e-94	-	-	-	S	-	-	-	Protein of unknown function (DUF1149)
HKANDMEF_01013	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HKANDMEF_01014	3.28e-296	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
HKANDMEF_01015	4.8e-310	ymfH	-	-	S	-	-	-	Peptidase M16
HKANDMEF_01016	3.01e-166	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
HKANDMEF_01017	1.15e-169	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
HKANDMEF_01018	3.46e-136	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HKANDMEF_01019	3.67e-294	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
HKANDMEF_01020	5.55e-245	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HKANDMEF_01021	7.95e-317	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
HKANDMEF_01022	5.06e-152	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
HKANDMEF_01023	1.47e-304	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
HKANDMEF_01024	4.32e-104	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
HKANDMEF_01025	3.24e-126	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HKANDMEF_01026	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HKANDMEF_01027	8.69e-239	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HKANDMEF_01028	1.56e-161	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	ABC transporter
HKANDMEF_01029	1.34e-200	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HKANDMEF_01030	7.77e-259	minJ	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
HKANDMEF_01031	1.83e-168	phoP	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HKANDMEF_01032	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HKANDMEF_01033	4.5e-199	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HKANDMEF_01034	4.48e-205	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HKANDMEF_01035	5.26e-202	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
HKANDMEF_01036	1.57e-192	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HKANDMEF_01037	2.49e-180	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HKANDMEF_01038	3.82e-156	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
HKANDMEF_01039	0.0	yvlB	-	-	S	-	-	-	Putative adhesin
HKANDMEF_01040	5.23e-50	-	-	-	-	-	-	-	-
HKANDMEF_01041	3.07e-50	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
HKANDMEF_01042	8.27e-223	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HKANDMEF_01043	7.94e-202	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HKANDMEF_01044	6.29e-250	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
HKANDMEF_01045	3.41e-230	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HKANDMEF_01046	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HKANDMEF_01047	1.51e-148	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
HKANDMEF_01048	4.14e-225	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
HKANDMEF_01049	8.85e-47	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
HKANDMEF_01050	2.03e-96	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HKANDMEF_01051	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HKANDMEF_01052	1.99e-153	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
HKANDMEF_01053	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HKANDMEF_01054	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HKANDMEF_01055	2.56e-111	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
HKANDMEF_01056	8.53e-213	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
HKANDMEF_01057	2.99e-248	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
HKANDMEF_01058	2.88e-221	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
HKANDMEF_01059	7.84e-106	ohrR	-	-	K	ko:K18906	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
HKANDMEF_01060	5.97e-132	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HKANDMEF_01062	8.72e-280	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HKANDMEF_01063	2.5e-184	-	-	-	-	-	-	-	-
HKANDMEF_01064	9.85e-49	-	-	-	-	-	-	-	-
HKANDMEF_01065	5.99e-154	-	-	-	P	ko:K10716	-	ko00000,ko02000	Ion transport protein
HKANDMEF_01066	3.75e-98	-	-	-	E	-	-	-	Zn peptidase
HKANDMEF_01067	1.9e-72	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HKANDMEF_01069	1.39e-183	-	-	-	K	-	-	-	ORF6N domain
HKANDMEF_01070	4.68e-77	-	-	-	S	-	-	-	Domain of unknown function (DUF771)
HKANDMEF_01076	6.5e-109	-	-	-	S	-	-	-	Siphovirus Gp157
HKANDMEF_01078	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
HKANDMEF_01079	1.89e-171	-	-	-	L	-	-	-	AAA domain
HKANDMEF_01080	4.92e-120	-	-	-	-	-	-	-	-
HKANDMEF_01081	6.41e-193	-	-	-	L	-	-	-	Bifunctional DNA primase/polymerase, N-terminal
HKANDMEF_01082	1.59e-302	-	-	-	S	ko:K06919	-	ko00000	Virulence-associated protein E
HKANDMEF_01083	1.66e-71	-	-	-	S	-	-	-	VRR_NUC
HKANDMEF_01084	5.25e-59	-	-	-	-	-	-	-	-
HKANDMEF_01086	7.3e-137	-	-	-	S	-	-	-	HNH endonuclease
HKANDMEF_01088	2.86e-93	-	-	-	S	-	-	-	Transcriptional regulator, RinA family
HKANDMEF_01089	2.61e-92	-	-	-	V	-	-	-	HNH endonuclease
HKANDMEF_01090	1.73e-83	-	-	-	-	-	-	-	-
HKANDMEF_01091	0.0	-	-	-	S	-	-	-	overlaps another CDS with the same product name
HKANDMEF_01092	3.57e-300	-	-	-	S	-	-	-	Phage portal protein
HKANDMEF_01093	1.68e-164	clpP	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
HKANDMEF_01094	4.08e-289	-	-	-	S	-	-	-	Phage capsid family
HKANDMEF_01096	9.08e-71	-	-	-	-	-	-	-	-
HKANDMEF_01097	3.92e-76	-	-	-	S	-	-	-	Phage head-tail joining protein
HKANDMEF_01098	1.28e-75	-	-	-	-	-	-	-	-
HKANDMEF_01099	9.07e-89	-	-	-	-	-	-	-	-
HKANDMEF_01100	2.82e-153	-	-	-	-	-	-	-	-
HKANDMEF_01101	1.73e-81	-	-	-	-	-	-	-	-
HKANDMEF_01102	0.0	-	-	-	D	-	-	-	Phage tail tape measure protein
HKANDMEF_01103	4.31e-165	-	-	-	S	-	-	-	phage tail
HKANDMEF_01104	0.0	-	-	-	LM	-	-	-	gp58-like protein
HKANDMEF_01105	2.91e-94	-	-	-	-	-	-	-	-
HKANDMEF_01106	1.62e-53	-	-	-	-	-	-	-	-
HKANDMEF_01107	5.45e-86	-	-	-	-	-	-	-	-
HKANDMEF_01109	6.86e-92	-	-	-	S	-	-	-	Bacteriophage holin of superfamily 6 (Holin_LLH)
HKANDMEF_01110	1.51e-261	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
HKANDMEF_01112	5.52e-241	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
HKANDMEF_01113	2.1e-247	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HKANDMEF_01114	2.16e-282	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
HKANDMEF_01115	2.81e-180	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HKANDMEF_01116	2.11e-315	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HKANDMEF_01117	6.34e-294	mdt(A)	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
HKANDMEF_01118	1.33e-63	-	-	-	-	-	-	-	-
HKANDMEF_01119	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HKANDMEF_01120	5.04e-43	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HKANDMEF_01121	2.82e-181	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Serine aminopeptidase, S33
HKANDMEF_01122	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HKANDMEF_01123	4.47e-108	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HKANDMEF_01124	2.3e-228	yvdE	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HKANDMEF_01125	0.0	malA1	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
HKANDMEF_01126	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HKANDMEF_01127	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
HKANDMEF_01128	1.8e-157	-	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HKANDMEF_01129	2.35e-270	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HKANDMEF_01130	0.0	dexB	3.2.1.70	-	G	ko:K01215	-	ko00000,ko01000	Alpha amylase, catalytic domain protein
HKANDMEF_01131	1.96e-292	mdxE	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HKANDMEF_01132	0.0	malF	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKANDMEF_01133	4.66e-196	malG	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HKANDMEF_01134	1.34e-22	-	-	-	-	-	-	-	-
HKANDMEF_01135	2.46e-36	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
HKANDMEF_01136	2.99e-310	YSH1	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Metallo-beta-lactamase superfamily
HKANDMEF_01137	4.3e-312	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HKANDMEF_01138	3.82e-189	malF	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKANDMEF_01139	1.42e-212	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	ABC-type sugar transport systems, permease components
HKANDMEF_01140	3.08e-248	malK	-	-	P	ko:K10112,ko:K17240	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
HKANDMEF_01141	3.63e-136	-	-	-	K	ko:K06977	-	ko00000	Acetyltransferase (GNAT) domain
HKANDMEF_01142	7.57e-119	-	-	-	-	-	-	-	-
HKANDMEF_01143	4e-203	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HKANDMEF_01144	1.45e-166	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HKANDMEF_01145	5.22e-229	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
HKANDMEF_01146	1.35e-107	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
HKANDMEF_01148	1.6e-214	ysdB	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKANDMEF_01149	2.2e-276	ysdA	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HKANDMEF_01150	1.97e-129	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HKANDMEF_01151	8.14e-194	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HKANDMEF_01152	4.74e-213	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
HKANDMEF_01153	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HKANDMEF_01154	1.97e-124	-	-	-	K	-	-	-	Cupin domain
HKANDMEF_01155	9.1e-263	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HKANDMEF_01156	2.49e-190	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HKANDMEF_01157	7.08e-188	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HKANDMEF_01158	8.49e-267	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HKANDMEF_01160	0.0	pacL	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
HKANDMEF_01161	2.42e-144	-	-	-	K	-	-	-	Transcriptional regulator
HKANDMEF_01162	1.69e-243	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HKANDMEF_01163	1.09e-169	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HKANDMEF_01164	3.82e-195	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HKANDMEF_01165	1.36e-217	ybbR	-	-	S	-	-	-	YbbR-like protein
HKANDMEF_01166	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HKANDMEF_01167	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HKANDMEF_01169	0.0	pepF2	-	-	E	-	-	-	Oligopeptidase F
HKANDMEF_01170	3.35e-106	-	-	-	S	-	-	-	VanZ like family
HKANDMEF_01171	5.85e-169	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
HKANDMEF_01172	1.02e-196	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
HKANDMEF_01173	7.91e-219	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
HKANDMEF_01174	1e-35	-	-	-	-	ko:K02245	-	ko00000,ko00002,ko02044	-
HKANDMEF_01176	8.98e-30	-	-	-	-	-	-	-	-
HKANDMEF_01177	2.01e-24	-	-	-	-	ko:K02248	-	ko00000,ko00002,ko02044	-
HKANDMEF_01179	3.73e-239	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
HKANDMEF_01180	2.1e-81	-	-	-	-	-	-	-	-
HKANDMEF_01181	0.0	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HKANDMEF_01182	7.51e-191	arbV	-	-	I	-	-	-	Phosphate acyltransferases
HKANDMEF_01183	2.02e-212	arbx	-	-	M	-	-	-	Glycosyl transferase family 8
HKANDMEF_01184	2.41e-235	arbY	-	-	M	-	-	-	family 8
HKANDMEF_01185	9.24e-214	arbZ	-	-	I	-	-	-	Phosphate acyltransferases
HKANDMEF_01186	0.0	rafA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HKANDMEF_01189	6.55e-93	-	-	-	S	-	-	-	SdpI/YhfL protein family
HKANDMEF_01190	3.55e-174	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
HKANDMEF_01191	0.0	yclK	-	-	T	-	-	-	Histidine kinase
HKANDMEF_01192	5.76e-22	-	-	-	S	-	-	-	acetyltransferase
HKANDMEF_01193	2.45e-75	-	-	-	S	-	-	-	acetyltransferase
HKANDMEF_01194	1.16e-19	-	-	-	-	-	-	-	-
HKANDMEF_01195	1.27e-94	pheB	5.4.99.5	-	S	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the UPF0735 family
HKANDMEF_01196	1.53e-88	-	-	-	-	-	-	-	-
HKANDMEF_01197	8.56e-74	-	-	-	-	-	-	-	-
HKANDMEF_01198	0.0	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
HKANDMEF_01200	3.92e-270	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
HKANDMEF_01201	1.28e-182	-	3.1.1.5	-	E	ko:K10804	ko01040,map01040	ko00000,ko00001,ko01000,ko01004	GDSL-like Lipase/Acylhydrolase
HKANDMEF_01202	5.65e-46	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF898)
HKANDMEF_01203	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
HKANDMEF_01204	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HKANDMEF_01205	3e-271	camS	-	-	S	-	-	-	sex pheromone
HKANDMEF_01206	3.61e-61	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HKANDMEF_01207	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HKANDMEF_01208	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HKANDMEF_01209	4.97e-248	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
HKANDMEF_01210	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HKANDMEF_01211	7.92e-282	yttB	-	-	EGP	-	-	-	Major Facilitator
HKANDMEF_01212	6.2e-191	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HKANDMEF_01213	8.52e-211	-	-	-	S	-	-	-	Polyphosphate nucleotide phosphotransferase, PPK2 family
HKANDMEF_01214	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
HKANDMEF_01215	0.0	-	-	-	EGP	-	-	-	Major Facilitator
HKANDMEF_01216	4.37e-107	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HKANDMEF_01217	2.87e-213	yitS	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
HKANDMEF_01218	3.38e-166	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
HKANDMEF_01219	4.3e-40	-	-	-	-	-	-	-	-
HKANDMEF_01220	6.15e-181	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HKANDMEF_01221	9.39e-80	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
HKANDMEF_01222	1.9e-79	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
HKANDMEF_01223	2.69e-227	mocA	-	-	S	-	-	-	Oxidoreductase
HKANDMEF_01224	1.79e-304	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
HKANDMEF_01225	2.76e-74	chbA	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system
HKANDMEF_01226	4.49e-93	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
HKANDMEF_01228	6.45e-06	-	-	-	-	-	-	-	-
HKANDMEF_01229	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HKANDMEF_01230	3.61e-309	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	Thermophilic metalloprotease (M29)
HKANDMEF_01231	2.96e-144	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKANDMEF_01232	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
HKANDMEF_01233	9.73e-230	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
HKANDMEF_01234	1.24e-103	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
HKANDMEF_01235	4.05e-205	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
HKANDMEF_01236	3.86e-261	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HKANDMEF_01238	5.92e-20	-	-	-	-	-	-	-	-
HKANDMEF_01239	1.09e-253	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
HKANDMEF_01240	4.58e-217	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HKANDMEF_01241	2.46e-215	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HKANDMEF_01242	2.5e-174	-	-	-	L	-	-	-	Helix-turn-helix domain
HKANDMEF_01245	2.44e-210	-	4.2.1.46	-	GM	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Male sterility protein
HKANDMEF_01246	1.72e-242	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
HKANDMEF_01247	4.89e-186	-	-	-	S	-	-	-	Cell surface protein
HKANDMEF_01249	0.0	-	-	-	N	-	-	-	domain, Protein
HKANDMEF_01250	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HKANDMEF_01251	0.0	bglH	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HKANDMEF_01252	7.44e-193	licT2	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HKANDMEF_01253	0.0	-	-	-	S	-	-	-	Bacterial membrane protein YfhO
HKANDMEF_01254	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HKANDMEF_01255	1.48e-220	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
HKANDMEF_01256	3.64e-134	-	-	-	-	-	-	-	-
HKANDMEF_01257	3.61e-218	yqjA	-	-	S	-	-	-	Putative aromatic acid exporter C-terminal domain
HKANDMEF_01258	6.22e-43	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
HKANDMEF_01259	4.8e-109	yvbK	-	-	K	-	-	-	GNAT family
HKANDMEF_01260	1.45e-149	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
HKANDMEF_01261	2.27e-132	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HKANDMEF_01262	6.23e-303	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
HKANDMEF_01263	1.15e-261	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HKANDMEF_01264	1.16e-315	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HKANDMEF_01265	3.79e-136	-	-	-	-	-	-	-	-
HKANDMEF_01266	6.04e-137	-	-	-	-	-	-	-	-
HKANDMEF_01267	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HKANDMEF_01268	7.87e-144	vanZ	-	-	V	-	-	-	VanZ like family
HKANDMEF_01269	4.66e-196	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
HKANDMEF_01270	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HKANDMEF_01271	8.89e-290	-	-	-	L	-	-	-	Pfam:Integrase_AP2
HKANDMEF_01274	4.15e-46	-	-	-	-	-	-	-	-
HKANDMEF_01275	2.49e-95	-	-	-	S	-	-	-	Pyridoxamine 5'-phosphate oxidase
HKANDMEF_01277	1.38e-282	-	-	-	J	-	-	-	Domain of unknown function (DUF4041)
HKANDMEF_01278	1.77e-74	-	-	-	-	-	-	-	-
HKANDMEF_01279	5.17e-140	-	-	-	-	-	-	-	-
HKANDMEF_01280	4e-100	-	-	-	E	-	-	-	Zn peptidase
HKANDMEF_01281	2.66e-74	-	-	-	K	-	-	-	Helix-turn-helix domain
HKANDMEF_01282	7.53e-10	-	-	-	K	-	-	-	sequence-specific DNA binding
HKANDMEF_01286	6.6e-129	-	-	-	-	-	-	-	-
HKANDMEF_01288	5.09e-23	-	-	-	-	-	-	-	-
HKANDMEF_01290	5.51e-205	recT	-	-	L	ko:K07455	-	ko00000,ko03400	RecT family
HKANDMEF_01291	2.86e-194	pi112	-	-	L	-	-	-	PDDEXK-like domain of unknown function (DUF3799)
HKANDMEF_01292	1.96e-206	-	-	-	L	-	-	-	Replication initiation and membrane attachment
HKANDMEF_01294	1.15e-86	-	-	-	S	-	-	-	Hypothetical protein (DUF2513)
HKANDMEF_01296	5.92e-09	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HKANDMEF_01297	6.44e-63	-	-	-	-	-	-	-	-
HKANDMEF_01298	4.6e-53	-	-	-	-	-	-	-	-
HKANDMEF_01299	7.92e-87	-	-	-	L	-	-	-	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
HKANDMEF_01300	1.74e-33	-	-	-	-	-	-	-	-
HKANDMEF_01302	1.94e-104	-	-	-	-	-	-	-	-
HKANDMEF_01305	9.14e-286	-	-	-	S	-	-	-	GcrA cell cycle regulator
HKANDMEF_01306	1.82e-71	-	-	-	-	-	-	-	-
HKANDMEF_01307	2.75e-125	-	-	-	L	ko:K07474	-	ko00000	Terminase small subunit
HKANDMEF_01308	5.98e-316	-	-	-	S	-	-	-	Terminase-like family
HKANDMEF_01309	0.0	-	-	-	S	-	-	-	Phage portal protein
HKANDMEF_01310	3.32e-239	-	-	-	S	-	-	-	head morphogenesis protein, SPP1 gp7 family
HKANDMEF_01311	8.55e-117	-	-	-	S	-	-	-	Domain of unknown function (DUF4355)
HKANDMEF_01312	6.27e-67	-	-	-	-	-	-	-	-
HKANDMEF_01313	8.25e-248	-	-	-	S	-	-	-	Phage major capsid protein E
HKANDMEF_01314	2.16e-45	-	-	-	-	-	-	-	-
HKANDMEF_01315	8.02e-230	-	-	-	-	-	-	-	-
HKANDMEF_01316	3.33e-85	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HKANDMEF_01317	5.68e-68	-	-	-	-	-	-	-	-
HKANDMEF_01318	2.28e-77	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
HKANDMEF_01319	4.75e-92	-	-	-	S	-	-	-	Protein of unknown function (DUF3168)
HKANDMEF_01320	5.97e-138	-	-	-	S	-	-	-	Phage tail tube protein
HKANDMEF_01321	9.32e-70	-	-	-	S	-	-	-	Phage tail assembly chaperone protein, TAC
HKANDMEF_01322	6.72e-88	-	-	-	-	-	-	-	-
HKANDMEF_01323	0.0	-	-	-	D	-	-	-	Phage tail tape measure protein
HKANDMEF_01324	0.0	-	-	-	S	-	-	-	Phage tail protein
HKANDMEF_01325	0.0	-	-	-	S	-	-	-	cellulase activity
HKANDMEF_01326	1.2e-70	-	-	-	-	-	-	-	-
HKANDMEF_01328	3.86e-70	-	-	-	-	-	-	-	-
HKANDMEF_01329	5.61e-84	hol	-	-	S	-	-	-	Bacteriophage holin
HKANDMEF_01330	7e-287	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HKANDMEF_01332	8.38e-186	-	-	-	S	-	-	-	Domain of unknown function DUF1829
HKANDMEF_01333	2.12e-63	ycnE	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
HKANDMEF_01335	1.69e-197	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
HKANDMEF_01336	2.7e-103	-	-	-	S	-	-	-	Pfam Transposase IS66
HKANDMEF_01337	1.72e-242	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
HKANDMEF_01338	6.79e-295	-	-	GT2,GT4	M	ko:K20444	-	ko00000,ko01000,ko01005,ko02000	Glycosyl transferases group 1
HKANDMEF_01339	1.09e-220	ysjB	-	-	S	ko:K03810	-	ko00000	Oxidoreductase family, NAD-binding Rossmann fold
HKANDMEF_01340	9.82e-111	guaD	-	-	FJ	-	-	-	MafB19-like deaminase
HKANDMEF_01342	5.18e-104	tspO	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	TspO/MBR family
HKANDMEF_01343	1.53e-19	-	-	-	-	-	-	-	-
HKANDMEF_01344	9.73e-275	yttB	-	-	EGP	-	-	-	Major Facilitator
HKANDMEF_01345	4.36e-136	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
HKANDMEF_01346	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HKANDMEF_01349	2.58e-166	pgm7	-	-	G	-	-	-	Phosphoglycerate mutase family
HKANDMEF_01350	6.41e-155	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKANDMEF_01351	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HKANDMEF_01352	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HKANDMEF_01353	1.29e-181	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HKANDMEF_01354	8.21e-212	catE	1.13.11.2	-	S	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	glyoxalase
HKANDMEF_01355	9.13e-252	ampC	-	-	V	-	-	-	Beta-lactamase
HKANDMEF_01356	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
HKANDMEF_01357	7.61e-144	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
HKANDMEF_01358	8.62e-252	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HKANDMEF_01359	2.32e-196	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HKANDMEF_01360	1.2e-238	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HKANDMEF_01361	1.57e-298	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HKANDMEF_01362	3.05e-145	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HKANDMEF_01363	1.23e-162	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HKANDMEF_01364	2.57e-37	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HKANDMEF_01365	1.13e-83	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HKANDMEF_01366	3.37e-117	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HKANDMEF_01367	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HKANDMEF_01368	1.92e-211	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HKANDMEF_01369	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HKANDMEF_01370	1.88e-91	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HKANDMEF_01371	8.38e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF1146)
HKANDMEF_01372	4.12e-228	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
HKANDMEF_01373	1.37e-26	-	-	-	S	-	-	-	DNA-directed RNA polymerase subunit beta
HKANDMEF_01374	1.14e-72	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
HKANDMEF_01375	8.37e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
HKANDMEF_01376	1.41e-285	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
HKANDMEF_01377	4.19e-65	gcsH2	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	glycine cleavage
HKANDMEF_01378	3.19e-284	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
HKANDMEF_01379	1.88e-186	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HKANDMEF_01380	8.04e-192	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HKANDMEF_01381	2.09e-243	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HKANDMEF_01382	9.25e-150	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HKANDMEF_01383	4.15e-184	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
HKANDMEF_01384	4.72e-244	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
HKANDMEF_01385	6.46e-285	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HKANDMEF_01386	1.72e-103	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
HKANDMEF_01387	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
HKANDMEF_01388	4.73e-31	-	-	-	-	-	-	-	-
HKANDMEF_01389	9.85e-88	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HKANDMEF_01390	3.03e-231	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
HKANDMEF_01391	1.29e-150	yhfA	-	-	S	-	-	-	HAD hydrolase, family IA, variant 3
HKANDMEF_01392	2.7e-200	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HKANDMEF_01393	2.86e-108	uspA	-	-	T	-	-	-	universal stress protein
HKANDMEF_01394	9.94e-54	-	-	-	-	-	-	-	-
HKANDMEF_01396	1.66e-306	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
HKANDMEF_01397	0.0	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
HKANDMEF_01398	1.17e-100	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HKANDMEF_01399	5.99e-143	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
HKANDMEF_01400	1.02e-158	sdaAB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
HKANDMEF_01401	1.61e-193	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HKANDMEF_01402	4.65e-158	-	-	-	G	-	-	-	alpha-ribazole phosphatase activity
HKANDMEF_01403	7.23e-200	mrsA1	1.8.4.11	-	O	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HKANDMEF_01404	1.81e-222	-	-	-	IQ	-	-	-	NAD dependent epimerase/dehydratase family
HKANDMEF_01405	2.93e-178	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
HKANDMEF_01406	2.05e-173	-	-	-	F	-	-	-	deoxynucleoside kinase
HKANDMEF_01407	4.04e-203	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidinol phosphatase and related hydrolases of the PHP family
HKANDMEF_01408	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HKANDMEF_01409	1.24e-202	-	-	-	T	-	-	-	GHKL domain
HKANDMEF_01410	2.69e-156	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
HKANDMEF_01411	1.17e-217	bcrA	-	-	V	ko:K01990,ko:K19309	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HKANDMEF_01412	4.43e-143	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HKANDMEF_01413	1.46e-207	-	-	-	K	-	-	-	Transcriptional regulator
HKANDMEF_01414	9.46e-103	yphH	-	-	S	-	-	-	Cupin domain
HKANDMEF_01415	1.07e-72	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	decarboxylase
HKANDMEF_01416	2.72e-149	-	-	-	GM	-	-	-	NAD(P)H-binding
HKANDMEF_01417	1.94e-54	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HKANDMEF_01418	4.73e-158	gst	2.5.1.18	-	O	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	ko00000,ko00001,ko01000,ko02000	Glutathione S-transferase, C-terminal domain
HKANDMEF_01419	2.07e-149	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HKANDMEF_01420	7.95e-219	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HKANDMEF_01421	3.03e-115	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HKANDMEF_01422	5.91e-199	degV	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
HKANDMEF_01423	2.07e-135	desR	-	-	K	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
HKANDMEF_01424	2.43e-264	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HKANDMEF_01425	1.17e-169	XK27_09830	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
HKANDMEF_01426	2.41e-203	yvfR	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HKANDMEF_01427	1.07e-281	-	-	-	-	-	-	-	-
HKANDMEF_01428	6.49e-90	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HKANDMEF_01429	4.87e-66	-	-	-	S	-	-	-	Protein of unknown function (DUF2568)
HKANDMEF_01430	4.9e-151	-	-	-	S	-	-	-	Protein of unknown function C-terminus (DUF2399)
HKANDMEF_01431	5.07e-157	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HKANDMEF_01432	1.23e-57	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
HKANDMEF_01433	8.76e-63	-	-	-	S	-	-	-	ParE toxin of type II toxin-antitoxin system, parDE
HKANDMEF_01435	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
HKANDMEF_01436	4.82e-226	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HKANDMEF_01438	3.6e-42	-	-	-	L	ko:K07481	-	ko00000	Transposase
HKANDMEF_01439	1.29e-151	-	-	-	L	-	-	-	Transposase
HKANDMEF_01440	2.47e-125	-	-	-	L	-	-	-	Transposase
HKANDMEF_01441	4.95e-134	-	-	-	S	ko:K06915	-	ko00000	AAA-like domain
HKANDMEF_01442	2.47e-251	-	-	-	S	ko:K06915	-	ko00000	helicase activity
HKANDMEF_01443	1.1e-227	-	-	-	S	-	-	-	SIR2-like domain
HKANDMEF_01445	0.0	-	-	-	-	-	-	-	-
HKANDMEF_01446	7.29e-06	-	-	-	-	-	-	-	-
HKANDMEF_01447	1.55e-10	-	-	-	L	-	-	-	Transposase IS66 family
HKANDMEF_01448	1.6e-10	-	-	-	L	ko:K07484	-	ko00000	PFAM transposase IS66
HKANDMEF_01449	5.31e-143	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HKANDMEF_01450	1.23e-111	yebR	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
HKANDMEF_01451	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HKANDMEF_01452	6.1e-272	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HKANDMEF_01453	6.03e-289	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HKANDMEF_01454	1.24e-148	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HKANDMEF_01455	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HKANDMEF_01456	3.79e-309	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HKANDMEF_01457	1.98e-148	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HKANDMEF_01458	1.97e-152	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
HKANDMEF_01459	4.82e-229	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
HKANDMEF_01460	3.25e-192	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
HKANDMEF_01461	1.23e-112	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
HKANDMEF_01462	2.31e-149	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HKANDMEF_01463	8.63e-182	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
HKANDMEF_01464	4.79e-142	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HKANDMEF_01465	3.29e-146	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
HKANDMEF_01466	2.32e-193	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
HKANDMEF_01467	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HKANDMEF_01468	7.11e-60	-	-	-	-	-	-	-	-
HKANDMEF_01469	1.61e-101	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HKANDMEF_01470	1.66e-219	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HKANDMEF_01471	1.6e-68	ftsL	-	-	D	-	-	-	cell division protein FtsL
HKANDMEF_01472	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HKANDMEF_01473	1.33e-230	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HKANDMEF_01474	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HKANDMEF_01475	4e-259	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HKANDMEF_01476	3.57e-201	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HKANDMEF_01477	1.44e-311	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HKANDMEF_01478	3.25e-291	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HKANDMEF_01479	7.24e-102	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HKANDMEF_01480	5.58e-60	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	integral membrane protein
HKANDMEF_01481	2.14e-188	ylmH	-	-	S	-	-	-	S4 domain protein
HKANDMEF_01482	2.12e-122	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA protein
HKANDMEF_01483	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HKANDMEF_01484	4.62e-48	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
HKANDMEF_01485	5.93e-207	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HKANDMEF_01486	0.0	ydiC1	-	-	EGP	-	-	-	Major Facilitator
HKANDMEF_01487	7.29e-270	yaaN	-	-	P	-	-	-	Toxic anion resistance protein (TelA)
HKANDMEF_01488	2.8e-151	-	-	-	S	-	-	-	5-bromo-4-chloroindolyl phosphate hydrolysis protein
HKANDMEF_01489	1.83e-124	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
HKANDMEF_01490	1.42e-39	-	-	-	-	-	-	-	-
HKANDMEF_01491	1.95e-159	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HKANDMEF_01492	1.39e-278	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HKANDMEF_01493	1.21e-75	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
HKANDMEF_01494	0.0	uvrA2	-	-	L	-	-	-	ABC transporter
HKANDMEF_01495	0.0	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HKANDMEF_01497	8.1e-160	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
HKANDMEF_01498	1.62e-151	-	-	-	S	-	-	-	repeat protein
HKANDMEF_01499	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HKANDMEF_01500	2.86e-312	-	-	-	S	-	-	-	Sterol carrier protein domain
HKANDMEF_01501	2.55e-46	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HKANDMEF_01502	3.58e-145	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HKANDMEF_01503	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HKANDMEF_01504	2.02e-43	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
HKANDMEF_01505	1.11e-95	-	-	-	-	-	-	-	-
HKANDMEF_01506	4.23e-64	-	-	-	-	-	-	-	-
HKANDMEF_01507	4.82e-132	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HKANDMEF_01508	5.13e-112	-	-	-	S	-	-	-	E1-E2 ATPase
HKANDMEF_01509	1.42e-267	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
HKANDMEF_01510	1.15e-232	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
HKANDMEF_01511	0.0	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HKANDMEF_01512	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
HKANDMEF_01513	4.32e-202	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	L-malate dehydrogenase activity
HKANDMEF_01514	6.15e-62	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
HKANDMEF_01515	3.56e-189	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
HKANDMEF_01516	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
HKANDMEF_01517	1.66e-269	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HKANDMEF_01518	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HKANDMEF_01519	8.46e-84	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
HKANDMEF_01520	9.93e-130	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
HKANDMEF_01521	1.08e-113	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HKANDMEF_01522	9.02e-234	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
HKANDMEF_01523	1.09e-151	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
HKANDMEF_01524	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
HKANDMEF_01525	5.08e-222	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
HKANDMEF_01526	1.44e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
HKANDMEF_01528	5e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HKANDMEF_01529	3.82e-62	-	-	-	-	-	-	-	-
HKANDMEF_01530	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HKANDMEF_01531	1.93e-213	-	-	-	S	-	-	-	Tetratricopeptide repeat
HKANDMEF_01532	4.73e-286	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HKANDMEF_01533	0.0	yknV	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter
HKANDMEF_01534	9.55e-288	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HKANDMEF_01535	1.19e-296	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HKANDMEF_01536	2.74e-138	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
HKANDMEF_01537	2.28e-63	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
HKANDMEF_01538	3.33e-28	-	-	-	-	-	-	-	-
HKANDMEF_01539	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HKANDMEF_01540	6.58e-173	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HKANDMEF_01541	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HKANDMEF_01542	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
HKANDMEF_01543	2.76e-218	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HKANDMEF_01544	1.61e-169	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
HKANDMEF_01545	5.83e-310	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HKANDMEF_01546	0.0	oatA	-	-	I	-	-	-	Acyltransferase
HKANDMEF_01547	2.71e-233	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HKANDMEF_01548	1.83e-183	yqjQ	-	-	S	ko:K07124	-	ko00000	Enoyl-(Acyl carrier protein) reductase
HKANDMEF_01549	2.47e-65	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
HKANDMEF_01550	0.0	clpB	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HKANDMEF_01551	1.35e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
HKANDMEF_01552	6.3e-123	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
HKANDMEF_01553	0.0	ycjM	3.1.3.5, 3.1.3.6, 3.1.4.16	-	F	ko:K01119,ko:K08693	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	5'-nucleotidase, C-terminal domain
HKANDMEF_01554	1.49e-185	-	-	-	-	-	-	-	-
HKANDMEF_01555	3.31e-35	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
HKANDMEF_01556	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
HKANDMEF_01557	2.21e-227	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HKANDMEF_01558	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
HKANDMEF_01559	2.6e-96	ytwI	-	-	S	-	-	-	Protein of unknown function (DUF441)
HKANDMEF_01560	1.03e-207	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
HKANDMEF_01561	9.95e-211	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
HKANDMEF_01563	1.59e-88	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HKANDMEF_01564	5.33e-160	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HKANDMEF_01565	8.74e-139	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HKANDMEF_01566	1.1e-175	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HKANDMEF_01567	1.52e-123	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HKANDMEF_01568	1.16e-60	fer	-	-	C	ko:K05337	-	ko00000	4Fe-4S single cluster domain of Ferredoxin I
HKANDMEF_01569	2.72e-236	-	-	-	S	-	-	-	Helix-turn-helix domain
HKANDMEF_01570	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HKANDMEF_01571	6.76e-111	-	-	-	M	-	-	-	Lysin motif
HKANDMEF_01572	2.04e-149	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
HKANDMEF_01573	1.72e-303	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
HKANDMEF_01574	7.41e-312	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HKANDMEF_01575	1.2e-54	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HKANDMEF_01576	1.52e-302	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
HKANDMEF_01577	8.71e-200	ypjC	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HKANDMEF_01578	5.31e-284	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HKANDMEF_01579	2.95e-110	-	-	-	-	-	-	-	-
HKANDMEF_01580	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HKANDMEF_01581	2.96e-244	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HKANDMEF_01582	3.64e-119	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HKANDMEF_01583	1.83e-148	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
HKANDMEF_01584	4.9e-190	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
HKANDMEF_01585	2.93e-197	XK27_03630	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HKANDMEF_01586	3.18e-147	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
HKANDMEF_01587	4.47e-113	msrA	1.8.4.11	-	C	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HKANDMEF_01588	1.03e-54	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
HKANDMEF_01589	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
HKANDMEF_01590	1.3e-52	XK27_02555	-	-	-	-	-	-	-
HKANDMEF_01592	7.6e-246	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
HKANDMEF_01593	2.52e-195	-	-	-	K	-	-	-	Helix-turn-helix domain
HKANDMEF_01595	2.53e-205	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HKANDMEF_01596	2.49e-179	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HKANDMEF_01597	3.27e-189	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
HKANDMEF_01598	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HKANDMEF_01599	0.0	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HKANDMEF_01600	1.66e-216	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
HKANDMEF_01601	2.06e-119	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HKANDMEF_01602	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HKANDMEF_01603	1.32e-219	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
HKANDMEF_01604	6.92e-141	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HKANDMEF_01605	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HKANDMEF_01606	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HKANDMEF_01607	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
HKANDMEF_01608	1.27e-217	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HKANDMEF_01609	2.6e-232	-	-	-	K	-	-	-	LysR substrate binding domain
HKANDMEF_01610	5.59e-221	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
HKANDMEF_01611	3.63e-270	xerS	-	-	L	ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
HKANDMEF_01612	7.18e-79	-	-	-	-	-	-	-	-
HKANDMEF_01613	0.0	XK27_05700	-	-	V	ko:K02004,ko:K19084	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	FtsX-like permease family
HKANDMEF_01614	2.68e-176	XK27_05695	-	-	V	ko:K02003,ko:K19083	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HKANDMEF_01615	1.09e-222	kinG	-	-	T	-	-	-	Histidine kinase-like ATPases
HKANDMEF_01616	1.75e-159	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
HKANDMEF_01617	5.52e-243	-	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
HKANDMEF_01618	1.07e-43	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HKANDMEF_01619	6.04e-94	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HKANDMEF_01620	2.92e-144	-	-	-	C	-	-	-	Nitroreductase family
HKANDMEF_01621	2.07e-261	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HKANDMEF_01622	6.09e-70	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	phosphoribosyl-ATP diphosphatase activity
HKANDMEF_01623	1.01e-77	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HKANDMEF_01624	7.36e-172	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HKANDMEF_01625	1.37e-160	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HKANDMEF_01626	4.89e-146	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HKANDMEF_01627	3.22e-135	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
HKANDMEF_01628	4.33e-297	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HKANDMEF_01629	2.06e-144	hisG	2.4.2.17	-	F	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HKANDMEF_01630	3.83e-278	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HKANDMEF_01631	6.2e-264	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HKANDMEF_01632	9.68e-134	-	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
HKANDMEF_01633	6.21e-207	-	-	-	S	-	-	-	EDD domain protein, DegV family
HKANDMEF_01634	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
HKANDMEF_01635	6.51e-69	-	-	-	S	-	-	-	MazG-like family
HKANDMEF_01636	1.42e-250	pfoS/R	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
HKANDMEF_01637	2.13e-227	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HKANDMEF_01638	9.61e-289	bfmBB	2.3.1.12, 2.3.1.168	-	C	ko:K00627,ko:K09699	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	2-oxoacid dehydrogenases acyltransferase (catalytic domain)
HKANDMEF_01639	2.14e-234	bfmBAB	1.2.4.4	-	C	ko:K00167,ko:K21417	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, pyrimidine binding domain
HKANDMEF_01640	9.14e-239	bfmBAA	1.2.4.4	-	C	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
HKANDMEF_01641	0.0	bfmBC	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain
HKANDMEF_01642	6.69e-263	buk	2.7.2.7	-	C	ko:K00929	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	Acetokinase family
HKANDMEF_01643	1.74e-190	ptb	2.3.1.19	-	C	ko:K00634	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	Phosphate acetyl/butaryl transferase
HKANDMEF_01644	1.02e-145	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HKANDMEF_01645	4.62e-164	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HKANDMEF_01646	5.67e-200	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HKANDMEF_01647	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HKANDMEF_01648	5.32e-267	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HKANDMEF_01649	5.35e-307	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HKANDMEF_01650	9.29e-230	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HKANDMEF_01651	1.64e-299	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
HKANDMEF_01652	1.05e-125	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HKANDMEF_01653	6.3e-223	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HKANDMEF_01654	2.41e-106	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HKANDMEF_01655	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
HKANDMEF_01656	8.5e-61	-	-	-	S	-	-	-	Family of unknown function (DUF5322)
HKANDMEF_01657	2.37e-91	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
HKANDMEF_01658	5.13e-144	XK27_02070	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
HKANDMEF_01659	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HKANDMEF_01660	3.85e-63	-	-	-	-	-	-	-	-
HKANDMEF_01661	0.0	-	-	-	S	-	-	-	Mga helix-turn-helix domain
HKANDMEF_01662	8.72e-52	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
HKANDMEF_01663	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HKANDMEF_01664	8.83e-242	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HKANDMEF_01665	2.26e-212	lysR	-	-	K	-	-	-	Transcriptional regulator
HKANDMEF_01666	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
HKANDMEF_01667	3.5e-249	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
HKANDMEF_01668	8.85e-47	-	-	-	-	-	-	-	-
HKANDMEF_01669	2.2e-223	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HKANDMEF_01670	2.31e-278	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
HKANDMEF_01671	7.09e-88	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HKANDMEF_01672	6.54e-138	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
HKANDMEF_01673	5.12e-157	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HKANDMEF_01674	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
HKANDMEF_01675	5.94e-111	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
HKANDMEF_01676	7.61e-148	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HKANDMEF_01677	3.19e-146	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
HKANDMEF_01678	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
HKANDMEF_01679	9.84e-281	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
HKANDMEF_01680	3.5e-112	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
HKANDMEF_01682	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
HKANDMEF_01683	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
HKANDMEF_01684	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HKANDMEF_01685	7.89e-217	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
HKANDMEF_01686	1.62e-232	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
HKANDMEF_01687	5.56e-245	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HKANDMEF_01688	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
HKANDMEF_01689	4.61e-224	-	-	-	-	-	-	-	-
HKANDMEF_01690	5.49e-185	-	-	-	-	-	-	-	-
HKANDMEF_01691	2.32e-79	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HKANDMEF_01692	1.48e-37	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
HKANDMEF_01693	1.4e-191	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HKANDMEF_01694	1.61e-162	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
HKANDMEF_01695	9.19e-249	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HKANDMEF_01696	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HKANDMEF_01697	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
HKANDMEF_01698	1.48e-219	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
HKANDMEF_01699	4.99e-72	-	-	-	-	-	-	-	-
HKANDMEF_01700	7.92e-74	-	-	-	-	-	-	-	-
HKANDMEF_01701	2.11e-183	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
HKANDMEF_01702	1.17e-217	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HKANDMEF_01703	1.38e-84	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HKANDMEF_01704	6.78e-82	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
HKANDMEF_01705	5.09e-107	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HKANDMEF_01706	8.02e-230	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
HKANDMEF_01708	1.81e-88	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
HKANDMEF_01709	3.98e-29	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
HKANDMEF_01710	8.44e-199	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HKANDMEF_01711	1.05e-211	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HKANDMEF_01712	3.1e-216	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HKANDMEF_01713	7.56e-108	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
HKANDMEF_01714	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HKANDMEF_01715	3.25e-311	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
HKANDMEF_01717	7.04e-217	-	-	-	C	-	-	-	nadph quinone reductase
HKANDMEF_01718	2.55e-100	-	-	-	-	-	-	-	-
HKANDMEF_01719	5.67e-191	-	-	-	K	-	-	-	Helix-turn-helix
HKANDMEF_01720	0.0	-	-	-	-	-	-	-	-
HKANDMEF_01721	2.41e-201	-	-	-	V	-	-	-	ABC transporter
HKANDMEF_01722	2.36e-109	-	-	-	FG	-	-	-	adenosine 5'-monophosphoramidase activity
HKANDMEF_01723	1.98e-314	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	N-acetylmuramoyl-L-alanine amidase
HKANDMEF_01724	1.35e-150	-	-	-	J	-	-	-	HAD-hyrolase-like
HKANDMEF_01725	5.55e-100	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HKANDMEF_01726	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HKANDMEF_01727	5.49e-58	-	-	-	-	-	-	-	-
HKANDMEF_01728	3.13e-170	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HKANDMEF_01729	1.74e-222	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
HKANDMEF_01730	3.49e-113	XK27_03960	-	-	S	-	-	-	Protein of unknown function (DUF3013)
HKANDMEF_01731	1.54e-144	-	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
HKANDMEF_01732	2.23e-50	-	-	-	-	-	-	-	-
HKANDMEF_01733	8.05e-88	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
HKANDMEF_01734	6.1e-27	-	-	-	-	-	-	-	-
HKANDMEF_01735	1.72e-64	-	-	-	-	-	-	-	-
HKANDMEF_01736	9.31e-117	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HKANDMEF_01738	3.1e-143	-	-	-	S	-	-	-	Flavodoxin-like fold
HKANDMEF_01739	1.54e-130	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKANDMEF_01740	7.25e-200	hutG	3.5.3.8	-	E	ko:K01479	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	N-formylglutamate amidohydrolase
HKANDMEF_01741	1.66e-71	XK27_08430	-	-	S	-	-	-	Staphylococcal protein of unknown function (DUF960)
HKANDMEF_01742	2.01e-118	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HKANDMEF_01743	1.7e-123	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HKANDMEF_01744	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
HKANDMEF_01745	8.85e-76	-	-	-	-	-	-	-	-
HKANDMEF_01746	2.05e-109	-	-	-	S	-	-	-	ASCH
HKANDMEF_01747	1.32e-33	-	-	-	-	-	-	-	-
HKANDMEF_01748	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HKANDMEF_01749	9.45e-261	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HKANDMEF_01750	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HKANDMEF_01751	3.18e-127	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HKANDMEF_01752	5.57e-247	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HKANDMEF_01753	1.01e-229	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
HKANDMEF_01754	1.22e-39	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
HKANDMEF_01755	2.3e-227	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HKANDMEF_01756	2.83e-213	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HKANDMEF_01757	4.46e-183	terC	-	-	P	-	-	-	Integral membrane protein TerC family
HKANDMEF_01758	1.27e-76	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HKANDMEF_01759	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HKANDMEF_01760	1.29e-60	ylxQ	-	-	J	-	-	-	ribosomal protein
HKANDMEF_01761	9.63e-61	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
HKANDMEF_01762	4.13e-277	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HKANDMEF_01763	1.33e-110	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
HKANDMEF_01764	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HKANDMEF_01765	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HKANDMEF_01766	3.52e-292	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
HKANDMEF_01767	7.66e-179	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
HKANDMEF_01768	6.38e-181	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HKANDMEF_01769	1.73e-121	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HKANDMEF_01770	5.86e-167	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HKANDMEF_01771	1.63e-200	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HKANDMEF_01772	1.18e-182	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
HKANDMEF_01773	1.88e-61	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
HKANDMEF_01774	2.05e-168	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
HKANDMEF_01775	8.45e-160	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
HKANDMEF_01776	1.17e-293	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
HKANDMEF_01777	4.28e-181	yejC	-	-	S	-	-	-	Protein of unknown function (DUF1003)
HKANDMEF_01778	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HKANDMEF_01779	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HKANDMEF_01780	1.39e-40	yneF	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
HKANDMEF_01781	2.96e-48	ynzC	-	-	S	-	-	-	UPF0291 protein
HKANDMEF_01782	9.42e-28	-	-	-	-	-	-	-	-
HKANDMEF_01783	2e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HKANDMEF_01784	6.15e-186	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
HKANDMEF_01785	2.16e-120	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HKANDMEF_01786	1.55e-51	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
HKANDMEF_01787	2.97e-59	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
HKANDMEF_01788	2.16e-303	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HKANDMEF_01789	1.26e-75	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HKANDMEF_01790	7.91e-70	-	-	-	-	-	-	-	-
HKANDMEF_01791	1.57e-233	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HKANDMEF_01792	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
HKANDMEF_01793	6.59e-160	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HKANDMEF_01794	0.0	oppA1	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HKANDMEF_01795	1.8e-197	oppC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKANDMEF_01796	3.2e-216	oppB	-	-	P	ko:K02033,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HKANDMEF_01797	5.65e-229	oppF	-	-	P	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HKANDMEF_01798	4.24e-247	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HKANDMEF_01799	3.21e-49	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HKANDMEF_01800	1.41e-241	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HKANDMEF_01801	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HKANDMEF_01802	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
HKANDMEF_01803	5.83e-75	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HKANDMEF_01804	2.29e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
HKANDMEF_01805	2.62e-166	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
HKANDMEF_01806	4.16e-151	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
HKANDMEF_01807	1.38e-221	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HKANDMEF_01808	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HKANDMEF_01809	7.73e-176	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
HKANDMEF_01810	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HKANDMEF_01811	9.71e-226	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HKANDMEF_01812	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HKANDMEF_01813	3.4e-276	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HKANDMEF_01814	1.77e-47	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HKANDMEF_01815	2.52e-148	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HKANDMEF_01816	6.35e-46	-	-	-	S	ko:K07001	-	ko00000	Patatin-like phospholipase
HKANDMEF_01817	3.99e-56	-	-	-	S	ko:K07001	-	ko00000	Patatin-like phospholipase
HKANDMEF_01818	2.32e-67	-	-	-	-	-	-	-	-
HKANDMEF_01820	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
HKANDMEF_01821	7.24e-97	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HKANDMEF_01822	8.09e-197	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
HKANDMEF_01823	1.56e-190	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HKANDMEF_01824	1.42e-43	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HKANDMEF_01825	1.56e-295	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HKANDMEF_01826	4.46e-193	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HKANDMEF_01827	2.34e-88	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HKANDMEF_01828	9.44e-99	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
HKANDMEF_01829	6.06e-132	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HKANDMEF_01831	2.14e-259	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HKANDMEF_01832	1.6e-63	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
HKANDMEF_01833	1.77e-74	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
HKANDMEF_01834	5.83e-67	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
HKANDMEF_01835	4.92e-18	-	-	-	-	-	-	-	-
HKANDMEF_01838	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HKANDMEF_01839	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HKANDMEF_01840	1.32e-80	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	Transcriptional regulator
HKANDMEF_01841	0.0	speA	4.1.1.17, 4.1.1.18, 4.1.1.19	-	E	ko:K01581,ko:K01582,ko:K01585	ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Orn/Lys/Arg decarboxylase, C-terminal domain
HKANDMEF_01842	1.41e-305	ynbB	-	-	P	-	-	-	aluminum resistance
HKANDMEF_01843	3.25e-224	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HKANDMEF_01844	3.33e-35	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
HKANDMEF_01845	1.93e-96	yqhL	-	-	P	-	-	-	Rhodanese-like protein
HKANDMEF_01846	1.13e-228	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
HKANDMEF_01847	6.79e-55	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
HKANDMEF_01848	2.3e-158	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
HKANDMEF_01849	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HKANDMEF_01850	2.14e-80	-	-	-	M	-	-	-	Bacterial membrane protein, YfhO
HKANDMEF_01851	1.72e-242	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
HKANDMEF_01852	0.0	-	-	-	S	-	-	-	Bacterial membrane protein YfhO
HKANDMEF_01853	8.3e-70	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
HKANDMEF_01854	2.04e-149	vraR	-	-	K	ko:K07694,ko:K11618	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
HKANDMEF_01855	1.39e-233	vraS	2.7.13.3	-	T	ko:K07681,ko:K11617	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HKANDMEF_01856	1.9e-165	yvqF	-	-	S	ko:K11622	ko02020,map02020	ko00000,ko00001	Cell wall-active antibiotics response 4TMS YvqF
HKANDMEF_01857	1.05e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HKANDMEF_01858	3.43e-148	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
HKANDMEF_01859	1.82e-265	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HKANDMEF_01860	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HKANDMEF_01861	1.24e-259	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HKANDMEF_01862	1.2e-87	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HKANDMEF_01863	3.09e-122	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HKANDMEF_01864	4.47e-178	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HKANDMEF_01865	4.17e-60	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
HKANDMEF_01866	8.99e-229	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HKANDMEF_01867	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HKANDMEF_01868	1.01e-157	csrR	-	-	K	-	-	-	response regulator
HKANDMEF_01869	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HKANDMEF_01870	1.9e-53	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HKANDMEF_01871	3.82e-128	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
HKANDMEF_01872	1.67e-270	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
HKANDMEF_01873	8.74e-181	yccK	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
HKANDMEF_01874	1.18e-78	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HKANDMEF_01875	1.31e-141	yqeK	-	-	H	-	-	-	Hydrolase, HD family
HKANDMEF_01876	5.06e-168	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HKANDMEF_01877	3.95e-65	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
HKANDMEF_01878	3.02e-262	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
HKANDMEF_01879	6.63e-127	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
HKANDMEF_01880	4.11e-222	ykcA	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HKANDMEF_01881	1.93e-243	mhqA_2	-	-	E	ko:K15975	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HKANDMEF_01882	2.14e-157	mhqD	-	-	S	ko:K06999	-	ko00000	Dienelactone hydrolase family
HKANDMEF_01883	4.5e-233	-	-	-	C	-	-	-	Alcohol dehydrogenase GroES-like domain
HKANDMEF_01884	1.01e-130	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
HKANDMEF_01885	1.02e-74	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HKANDMEF_01886	1.13e-36	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
HKANDMEF_01887	7.46e-101	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HKANDMEF_01888	2.31e-167	-	-	-	S	-	-	-	SseB protein N-terminal domain
HKANDMEF_01889	5.3e-70	-	-	-	-	-	-	-	-
HKANDMEF_01890	4.61e-137	yrgI	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Histidine phosphatase superfamily (branch 1)
HKANDMEF_01891	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HKANDMEF_01893	2.02e-219	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
HKANDMEF_01894	0.0	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
HKANDMEF_01895	2.06e-103	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HKANDMEF_01896	2.82e-132	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HKANDMEF_01897	7.86e-207	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HKANDMEF_01898	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HKANDMEF_01899	4.41e-156	ybhL	-	-	S	ko:K06890	-	ko00000	Inhibitor of apoptosis-promoting Bax1
HKANDMEF_01900	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
HKANDMEF_01901	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HKANDMEF_01902	5.48e-150	XK27_10290	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HKANDMEF_01903	5.32e-73	ytpP	-	-	CO	-	-	-	Thioredoxin
HKANDMEF_01905	8.13e-157	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HKANDMEF_01906	4.51e-189	ytmP	-	-	M	-	-	-	Choline/ethanolamine kinase
HKANDMEF_01907	6.39e-279	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HKANDMEF_01908	2.4e-172	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKANDMEF_01909	1.67e-99	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
HKANDMEF_01910	2.44e-82	-	-	-	S	-	-	-	YtxH-like protein
HKANDMEF_01911	5.26e-205	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HKANDMEF_01912	8.42e-232	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
HKANDMEF_01913	1.03e-72	-	-	-	S	-	-	-	Control of competence regulator ComK, YlbF/YmcA
HKANDMEF_01914	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HKANDMEF_01915	1.3e-198	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
HKANDMEF_01916	3.31e-98	argR1	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HKANDMEF_01917	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
HKANDMEF_01919	1.97e-88	-	-	-	-	-	-	-	-
HKANDMEF_01920	4.04e-32	-	-	-	-	-	-	-	-
HKANDMEF_01921	3.67e-227	pyrD	1.3.5.2, 1.3.98.1	-	F	ko:K00226,ko:K00254	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dihydroorotate to orotate
HKANDMEF_01922	0.0	glpQ4	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
HKANDMEF_01923	3.53e-158	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HKANDMEF_01924	1.13e-89	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HKANDMEF_01925	3.42e-178	yhfI	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
HKANDMEF_01926	7.88e-121	traP	1.14.99.57, 6.2.1.3	-	S	ko:K01897,ko:K21481	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	heme oxygenase (decyclizing) activity
HKANDMEF_01927	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease)
HKANDMEF_01928	1.14e-177	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HKANDMEF_01929	1.57e-159	rrp1	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
HKANDMEF_01930	1.21e-266	-	-	-	T	ko:K19168	-	ko00000,ko02048	His Kinase A (phosphoacceptor) domain
HKANDMEF_01931	1.54e-141	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HKANDMEF_01932	0.0	copB	3.6.3.3, 3.6.3.4, 3.6.3.5	-	P	ko:K01533,ko:K01534	-	ko00000,ko01000	P-type ATPase
HKANDMEF_01933	2.87e-101	copR	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
HKANDMEF_01934	4.69e-301	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
HKANDMEF_01935	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
HKANDMEF_01936	2.36e-130	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HKANDMEF_01937	7.52e-239	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
HKANDMEF_01938	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HKANDMEF_01939	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HKANDMEF_01940	3.05e-168	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HKANDMEF_01941	7.25e-56	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HKANDMEF_01942	1.63e-172	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
HKANDMEF_01943	8.98e-276	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HKANDMEF_01944	2.66e-102	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HKANDMEF_01945	6.68e-136	thiT	-	-	S	ko:K16789	-	ko00000,ko02000	Thiamine transporter protein (Thia_YuaJ)
HKANDMEF_01946	0.0	iolT	-	-	EGP	ko:K06609	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HKANDMEF_01947	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HKANDMEF_01948	1.02e-51	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
HKANDMEF_01949	9.5e-39	-	-	-	-	-	-	-	-
HKANDMEF_01950	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
HKANDMEF_01951	1.17e-61	XK27_09445	-	-	S	-	-	-	Domain of unknown function (DUF1827)
HKANDMEF_01953	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HKANDMEF_01954	1.44e-311	hlyX	-	-	S	ko:K03699	-	ko00000,ko02042	Transporter associated domain
HKANDMEF_01955	4.17e-262	yueF	-	-	S	-	-	-	AI-2E family transporter
HKANDMEF_01956	1.13e-97	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HKANDMEF_01957	1.92e-123	-	-	-	-	-	-	-	-
HKANDMEF_01958	1.1e-134	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
HKANDMEF_01959	3.39e-183	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
HKANDMEF_01960	0.0	frvR	-	-	K	ko:K02538,ko:K03483,ko:K09685,ko:K18531	-	ko00000,ko03000	transcriptional antiterminator
HKANDMEF_01961	6.46e-83	-	-	-	-	-	-	-	-
HKANDMEF_01962	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HKANDMEF_01963	4.13e-104	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
HKANDMEF_01964	2.13e-172	-	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
HKANDMEF_01965	0.0	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HKANDMEF_01966	0.0	celD	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKANDMEF_01967	2.36e-111	-	-	-	-	-	-	-	-
HKANDMEF_01968	1.94e-66	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
HKANDMEF_01969	6.27e-67	ptcB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HKANDMEF_01970	0.0	poxL	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HKANDMEF_01971	2.6e-279	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
HKANDMEF_01972	1.63e-267	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
HKANDMEF_01973	1.41e-265	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
HKANDMEF_01974	7.23e-66	-	-	-	-	-	-	-	-
HKANDMEF_01975	3.47e-207	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
HKANDMEF_01976	4.44e-134	-	-	-	V	ko:K07448	-	ko00000,ko02048	Restriction endonuclease
HKANDMEF_01977	2.25e-201	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	converts alpha-aldose to the beta-anomer
HKANDMEF_01978	1.88e-272	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
HKANDMEF_01979	4.33e-132	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
HKANDMEF_01981	1.4e-105	-	-	-	K	-	-	-	Acetyltransferase GNAT Family
HKANDMEF_01982	1.65e-111	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
HKANDMEF_01983	2.36e-167	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKANDMEF_01984	2.83e-188	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HKANDMEF_01985	2.53e-48	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
HKANDMEF_01986	7.4e-165	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
HKANDMEF_01988	2.88e-96	-	-	-	-	-	-	-	-
HKANDMEF_01989	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HKANDMEF_01990	4.84e-278	-	-	-	V	-	-	-	Beta-lactamase
HKANDMEF_01991	2.51e-195	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HKANDMEF_01992	3.31e-282	-	-	-	V	-	-	-	Beta-lactamase
HKANDMEF_01993	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HKANDMEF_01994	1.62e-161	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
HKANDMEF_01995	7.45e-280	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HKANDMEF_01996	1.13e-177	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HKANDMEF_01997	0.0	yuxL	3.4.19.1	-	E	ko:K01303	-	ko00000,ko01000,ko01002	Prolyl oligopeptidase family
HKANDMEF_02000	2.17e-205	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HKANDMEF_02001	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
HKANDMEF_02002	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKANDMEF_02003	1.71e-87	-	-	-	-	-	-	-	-
HKANDMEF_02004	6.13e-100	-	-	-	S	-	-	-	function, without similarity to other proteins
HKANDMEF_02005	0.0	-	-	-	G	-	-	-	MFS/sugar transport protein
HKANDMEF_02006	4.07e-296	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
HKANDMEF_02007	8.15e-77	-	-	-	-	-	-	-	-
HKANDMEF_02008	0.0	pckA	4.1.1.49	-	C	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
HKANDMEF_02009	6.28e-25	-	-	-	S	-	-	-	Virus attachment protein p12 family
HKANDMEF_02010	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
HKANDMEF_02011	8.65e-56	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA
HKANDMEF_02012	2.02e-168	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
HKANDMEF_02015	3.72e-152	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
HKANDMEF_02016	8.14e-79	-	-	-	S	-	-	-	MucBP domain
HKANDMEF_02017	9.73e-109	-	-	-	-	-	-	-	-
HKANDMEF_02021	5.19e-90	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
HKANDMEF_02024	1.33e-294	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HKANDMEF_02025	0.0	-	-	-	K	-	-	-	Mga helix-turn-helix domain
HKANDMEF_02026	0.0	-	-	-	K	-	-	-	Mga helix-turn-helix domain
HKANDMEF_02027	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
HKANDMEF_02029	4.15e-170	budA	4.1.1.5	-	Q	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
HKANDMEF_02030	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
HKANDMEF_02031	8.32e-128	-	-	-	-	-	-	-	-
HKANDMEF_02032	2.94e-128	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HKANDMEF_02033	3e-249	-	-	-	S	-	-	-	Protein of unknown function C-terminal (DUF3324)
HKANDMEF_02034	8.02e-114	-	-	-	-	-	-	-	-
HKANDMEF_02035	1.43e-25	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HKANDMEF_02036	3.08e-152	sodA	1.15.1.1	-	C	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HKANDMEF_02037	2.44e-208	yjbO	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HKANDMEF_02038	1.25e-201	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HKANDMEF_02039	1.61e-41	-	-	-	-	-	-	-	-
HKANDMEF_02040	7.43e-97	-	-	-	-	-	-	-	-
HKANDMEF_02041	1.99e-199	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HKANDMEF_02042	4.14e-163	citR	-	-	K	-	-	-	FCD
HKANDMEF_02043	0.0	oadA	4.1.1.3	-	C	ko:K01571	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	Conserved carboxylase domain
HKANDMEF_02044	1.18e-122	citX	2.7.7.61	-	HI	ko:K05964	ko02020,map02020	ko00000,ko00001,ko01000	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
HKANDMEF_02045	0.0	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
HKANDMEF_02046	7.46e-201	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
HKANDMEF_02047	3.41e-65	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
HKANDMEF_02048	4.66e-232	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HKANDMEF_02049	3.26e-07	-	-	-	-	-	-	-	-
HKANDMEF_02050	5.58e-251	oadB	4.1.1.3	-	C	ko:K01572	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	Na+-transporting oxaloacetate decarboxylase beta subunit
HKANDMEF_02051	1.71e-62	oadG	-	-	I	-	-	-	Biotin-requiring enzyme
HKANDMEF_02052	3.17e-71	-	-	-	-	-	-	-	-
HKANDMEF_02053	1.43e-307	citM	-	-	C	ko:K03300	-	ko00000	Citrate transporter
HKANDMEF_02054	1.72e-53	-	-	-	-	-	-	-	-
HKANDMEF_02055	2.68e-135	kptA	-	-	J	ko:K07559	-	ko00000,ko01000,ko03016	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
HKANDMEF_02056	2.1e-114	-	-	-	K	-	-	-	GNAT family
HKANDMEF_02057	6.93e-140	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
HKANDMEF_02058	1.13e-75	padR	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
HKANDMEF_02059	7.71e-192	ORF00048	-	-	-	-	-	-	-
HKANDMEF_02060	6.35e-177	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
HKANDMEF_02061	1.42e-216	ybhF_1	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HKANDMEF_02062	0.0	-	-	-	M	ko:K01992	-	ko00000,ko00002,ko02000	Exporter of polyketide antibiotics
HKANDMEF_02063	1.7e-148	-	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
HKANDMEF_02064	0.0	-	-	-	EGP	-	-	-	Major Facilitator
HKANDMEF_02065	2.86e-161	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HKANDMEF_02066	6.95e-239	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HKANDMEF_02067	4.73e-209	-	-	-	S	-	-	-	Alpha beta hydrolase
HKANDMEF_02068	8.13e-82	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
HKANDMEF_02069	1.23e-163	yhcG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HKANDMEF_02070	4.41e-20	-	-	-	-	-	-	-	-
HKANDMEF_02071	6.6e-134	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HKANDMEF_02072	1.71e-206	-	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
HKANDMEF_02073	3.16e-262	-	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
HKANDMEF_02075	7.11e-228	-	-	-	EP	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HKANDMEF_02076	2.54e-216	-	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKANDMEF_02077	0.0	-	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HKANDMEF_02078	1.19e-164	-	-	-	S	-	-	-	DJ-1/PfpI family
HKANDMEF_02079	2.12e-70	-	-	-	K	-	-	-	Transcriptional
HKANDMEF_02080	6.68e-52	-	-	-	-	-	-	-	-
HKANDMEF_02081	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
HKANDMEF_02082	0.0	-	-	-	V	ko:K06147,ko:K06148,ko:K11085,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter transmembrane region
HKANDMEF_02084	3.24e-89	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
HKANDMEF_02085	7.96e-20	-	2.7.1.39	-	S	ko:K02204	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Phosphotransferase enzyme family
HKANDMEF_02086	0.0	-	-	-	M	-	-	-	LysM domain
HKANDMEF_02087	3.38e-173	zmp3	-	-	O	-	-	-	Zinc-dependent metalloprotease
HKANDMEF_02088	4.82e-226	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HKANDMEF_02089	1.23e-176	-	-	-	K	-	-	-	DeoR C terminal sensor domain
HKANDMEF_02091	7.74e-68	lciIC	-	-	K	-	-	-	Helix-turn-helix domain
HKANDMEF_02092	9.14e-129	yjdB	-	-	S	-	-	-	Domain of unknown function (DUF4767)
HKANDMEF_02093	1.35e-192	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HKANDMEF_02094	2.09e-98	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HKANDMEF_02095	8.4e-150	-	-	-	-	-	-	-	-
HKANDMEF_02097	1.51e-77	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
HKANDMEF_02098	8.37e-108	-	-	-	L	-	-	-	Transposase DDE domain
HKANDMEF_02099	2.44e-143	-	-	-	L	ko:K07482	-	ko00000	Transposase and inactivated derivatives, IS30 family
HKANDMEF_02100	1.5e-107	-	-	-	-	-	-	-	-
HKANDMEF_02101	1.4e-58	-	-	-	L	ko:K07483	-	ko00000	Homeodomain-like domain
HKANDMEF_02102	4.17e-189	-	-	-	L	-	-	-	COG2801 Transposase and inactivated derivatives
HKANDMEF_02103	4.68e-71	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
HKANDMEF_02104	2.96e-212	-	-	-	P	-	-	-	CorA-like Mg2+ transporter protein
HKANDMEF_02105	4.82e-226	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HKANDMEF_02106	3.96e-224	-	-	-	I	-	-	-	Alpha/beta hydrolase family
HKANDMEF_02107	3.74e-204	dppA	-	-	E	ko:K16203	-	ko00000,ko01000,ko01002	D-aminopeptidase
HKANDMEF_02108	6e-269	pepA	-	-	E	-	-	-	M42 glutamyl aminopeptidase
HKANDMEF_02109	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HKANDMEF_02110	2.14e-163	tnp1216	-	-	L	ko:K07498	-	ko00000	DDE domain
HKANDMEF_02111	1.4e-09	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	type I restriction modification DNA specificity domain
HKANDMEF_02112	5.78e-32	-	-	-	-	-	-	-	-
HKANDMEF_02113	2.56e-86	-	-	-	-	-	-	-	-
HKANDMEF_02115	1.35e-33	-	-	-	S	-	-	-	Domain of unknown function (DUF3173)
HKANDMEF_02116	3e-294	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HKANDMEF_02117	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
HKANDMEF_02118	8.03e-229	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
HKANDMEF_02120	3.38e-56	-	-	-	-	-	-	-	-
HKANDMEF_02121	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HKANDMEF_02122	1.5e-111	ykhA	3.1.2.20	-	I	ko:K01073	-	ko00000,ko01000	Thioesterase superfamily
HKANDMEF_02123	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HKANDMEF_02124	2.51e-28	-	-	-	-	-	-	-	-
HKANDMEF_02125	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
HKANDMEF_02126	1.97e-230	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HKANDMEF_02127	1.11e-106	yjhE	-	-	S	-	-	-	Phage tail protein
HKANDMEF_02128	1.09e-307	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HKANDMEF_02129	4.91e-241	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
HKANDMEF_02130	4.03e-164	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
HKANDMEF_02131	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HKANDMEF_02132	2.68e-174	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKANDMEF_02133	0.0	-	-	-	E	-	-	-	Amino Acid
HKANDMEF_02134	8.52e-212	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HKANDMEF_02135	4.57e-304	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HKANDMEF_02136	4.67e-215	nodB3	-	-	G	-	-	-	Polysaccharide deacetylase
HKANDMEF_02137	0.0	-	-	-	S	-	-	-	Glucosyl transferase GtrII
HKANDMEF_02138	4.68e-300	-	-	-	-	-	-	-	-
HKANDMEF_02139	3.07e-124	-	-	-	-	-	-	-	-
HKANDMEF_02140	1.19e-234	-	-	-	M	-	-	-	Peptidase_C39 like family
HKANDMEF_02141	1.12e-205	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HKANDMEF_02142	8.36e-259	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HKANDMEF_02143	1.55e-140	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HKANDMEF_02144	7.88e-211	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HKANDMEF_02146	9.51e-168	-	-	-	-	-	-	-	-
HKANDMEF_02147	0.0	cps2E	-	-	M	-	-	-	Bacterial sugar transferase
HKANDMEF_02148	8e-226	cps2D	5.1.3.2, 5.1.3.25	-	M	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
HKANDMEF_02149	2.27e-141	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HKANDMEF_02150	1.44e-141	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HKANDMEF_02151	1.23e-190	glnH	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HKANDMEF_02152	6.35e-174	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HKANDMEF_02153	8.02e-230	-	-	-	-	-	-	-	-
HKANDMEF_02155	3.91e-109	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
HKANDMEF_02156	9.35e-15	-	-	-	-	-	-	-	-
HKANDMEF_02157	7.28e-144	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
HKANDMEF_02158	7.28e-92	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HKANDMEF_02159	1.99e-197	spl	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
HKANDMEF_02160	1.55e-312	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HKANDMEF_02161	1.32e-221	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HKANDMEF_02162	5.83e-73	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HKANDMEF_02163	3.12e-222	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HKANDMEF_02164	0.0	malZ	3.2.1.20, 3.2.1.41	CBM48,GH13,GH31	G	ko:K01187,ko:K01200	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HKANDMEF_02165	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HKANDMEF_02166	0.0	glgA	2.4.1.21	GT5	F	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
HKANDMEF_02167	1.45e-281	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
HKANDMEF_02168	1.18e-255	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HKANDMEF_02169	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HKANDMEF_02170	1.06e-262	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
HKANDMEF_02171	5.01e-136	-	-	-	M	-	-	-	Sortase family
HKANDMEF_02172	2.29e-187	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HKANDMEF_02173	0.0	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	phosphatase activity
HKANDMEF_02174	1.94e-86	spx2	-	-	P	ko:K16509	-	ko00000	ArsC family
HKANDMEF_02175	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	associated with various cellular activities
HKANDMEF_02176	4.87e-187	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
HKANDMEF_02177	1.11e-205	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HKANDMEF_02178	3.21e-243	-	-	-	-	-	-	-	-
HKANDMEF_02179	6.93e-169	-	-	-	L	-	-	-	Transposase and inactivated derivatives
HKANDMEF_02180	0.0	-	-	-	L	-	-	-	Transposase DDE domain
HKANDMEF_02181	1.65e-241	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HKANDMEF_02182	4.21e-206	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HKANDMEF_02183	7.16e-260	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HKANDMEF_02184	1.55e-140	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HKANDMEF_02185	3.21e-210	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HKANDMEF_02186	4.13e-94	rfbP	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
HKANDMEF_02187	7.56e-208	-	-	-	S	ko:K07011	-	ko00000	Glycosyltransferase like family 2
HKANDMEF_02188	0.0	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
HKANDMEF_02189	2.93e-133	-	-	-	S	-	-	-	Hexapeptide repeat of succinyl-transferase
HKANDMEF_02190	7.01e-286	-	-	-	S	-	-	-	O-antigen ligase like membrane protein
HKANDMEF_02191	8.31e-234	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HKANDMEF_02192	1.14e-276	-	-	-	M	-	-	-	Glycosyl transferases group 1
HKANDMEF_02193	3.79e-295	rgpAc	-	GT4	M	ko:K12996	-	ko00000,ko01000,ko01003,ko01005	Domain of unknown function (DUF1972)
HKANDMEF_02194	3.75e-165	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
HKANDMEF_02195	1.43e-186	epsB	-	-	M	-	-	-	biosynthesis protein
HKANDMEF_02196	3.68e-170	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
HKANDMEF_02197	4.2e-106	ccl	-	-	S	-	-	-	QueT transporter
HKANDMEF_02198	4.62e-163	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
HKANDMEF_02199	2.1e-49	XK27_01315	-	-	S	-	-	-	Protein of unknown function (DUF2829)
HKANDMEF_02200	6.56e-64	-	-	-	K	-	-	-	sequence-specific DNA binding
HKANDMEF_02201	1.07e-151	gpm5	-	-	G	-	-	-	Phosphoglycerate mutase family
HKANDMEF_02202	3.15e-230	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HKANDMEF_02203	4.99e-251	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HKANDMEF_02204	3.01e-227	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HKANDMEF_02205	1.4e-208	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HKANDMEF_02206	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HKANDMEF_02207	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HKANDMEF_02208	1.72e-242	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
HKANDMEF_02209	4.1e-130	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HKANDMEF_02210	1.98e-172	lutC	-	-	S	ko:K00782	-	ko00000	LUD domain
HKANDMEF_02211	0.0	lutB	-	-	C	ko:K18929	-	ko00000	4Fe-4S dicluster domain
HKANDMEF_02212	1.7e-190	lutA	-	-	C	ko:K18928	-	ko00000	Cysteine-rich domain
HKANDMEF_02213	2.39e-109	-	-	-	-	-	-	-	-
HKANDMEF_02214	1.09e-68	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase system cellobiose-specific component IIA
HKANDMEF_02215	3.77e-270	ybhE	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
HKANDMEF_02216	1.62e-90	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
HKANDMEF_02217	7.79e-11	-	-	-	-	-	-	-	-
HKANDMEF_02218	0.0	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKANDMEF_02219	0.0	galA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HKANDMEF_02220	1.34e-176	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
HKANDMEF_02221	3.16e-180	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2087)
HKANDMEF_02222	0.0	-	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Helix-hairpin-helix containing domain
HKANDMEF_02223	5.16e-17	-	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Helix-hairpin-helix containing domain
HKANDMEF_02224	1.25e-102	-	-	-	-	-	-	-	-
HKANDMEF_02225	5.33e-76	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HKANDMEF_02226	4.13e-187	frlD1	2.7.1.218	-	G	ko:K10710	-	ko00000,ko01000	pfkB family carbohydrate kinase
HKANDMEF_02227	0.0	hyuA	-	-	EQ	-	-	-	Hydantoinase/oxoprolinase N-terminal region
HKANDMEF_02228	9.15e-264	-	-	-	S	ko:K09703	-	ko00000	Protein of unknown function (DUF917)
HKANDMEF_02229	8.79e-283	-	-	-	F	ko:K10974	-	ko00000,ko02000	Permease for cytosine/purines, uracil, thiamine, allantoin
HKANDMEF_02230	1.44e-186	-	-	-	-	-	-	-	-
HKANDMEF_02231	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF1524)
HKANDMEF_02232	1.17e-261	hsdS	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	type I restriction modification DNA specificity domain
HKANDMEF_02233	4.28e-224	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HKANDMEF_02234	7.59e-122	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
HKANDMEF_02235	4.23e-219	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
HKANDMEF_02236	1.01e-165	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
HKANDMEF_02237	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
HKANDMEF_02238	2.47e-136	-	-	-	-	-	-	-	-
HKANDMEF_02239	0.0	-	-	-	-	-	-	-	-
HKANDMEF_02240	3.5e-271	-	-	-	-	-	-	-	-
HKANDMEF_02241	6.8e-95	pts26BCA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HKANDMEF_02242	0.0	pts26BCA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HKANDMEF_02243	0.0	malL	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HKANDMEF_02244	3.69e-233	purR2	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
HKANDMEF_02245	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
HKANDMEF_02246	5.14e-212	-	-	-	GM	-	-	-	NmrA-like family
HKANDMEF_02247	4.81e-298	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
HKANDMEF_02248	1.19e-184	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
HKANDMEF_02249	3.05e-194	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HKANDMEF_02250	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
HKANDMEF_02251	2.76e-99	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HKANDMEF_02252	8.8e-93	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HKANDMEF_02253	6.98e-284	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HKANDMEF_02254	2.03e-164	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
HKANDMEF_02255	1.52e-212	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
HKANDMEF_02256	5.55e-221	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
HKANDMEF_02257	1.38e-45	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HKANDMEF_02258	1.96e-226	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HKANDMEF_02259	2.44e-99	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HKANDMEF_02260	6.79e-95	-	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
HKANDMEF_02261	7.3e-246	-	-	-	E	-	-	-	Alpha/beta hydrolase family
HKANDMEF_02262	5.57e-290	-	-	-	C	-	-	-	Iron-containing alcohol dehydrogenase
HKANDMEF_02263	1.72e-242	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
HKANDMEF_02264	4.19e-65	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2316)
HKANDMEF_02265	1.35e-88	-	-	-	K	ko:K18909	-	ko00000,ko00002,ko01504,ko03000	MarR family
HKANDMEF_02266	1.24e-14	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
HKANDMEF_02267	3.72e-218	-	-	-	S	-	-	-	Putative esterase
HKANDMEF_02268	1.83e-256	-	-	-	-	-	-	-	-
HKANDMEF_02269	1.47e-136	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
HKANDMEF_02270	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
HKANDMEF_02271	4.68e-109	-	-	-	F	-	-	-	NUDIX domain
HKANDMEF_02272	4.68e-168	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HKANDMEF_02273	9.57e-30	-	-	-	-	-	-	-	-
HKANDMEF_02274	1.09e-209	-	-	-	S	-	-	-	zinc-ribbon domain
HKANDMEF_02275	5.93e-262	pbpX	-	-	V	-	-	-	Beta-lactamase
HKANDMEF_02276	4.01e-240	ydbI	-	-	K	-	-	-	AI-2E family transporter
HKANDMEF_02277	4.31e-166	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
HKANDMEF_02278	1.41e-85	gtcA2	-	-	S	-	-	-	Teichoic acid glycosylation protein
HKANDMEF_02279	2.58e-226	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HKANDMEF_02280	0.0	-	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HKANDMEF_02281	3.51e-216	gbuC	-	-	E	ko:K02001,ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
HKANDMEF_02282	2.03e-189	gbuB	-	-	E	ko:K02001	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
HKANDMEF_02283	9.19e-285	gbuA	3.6.3.32	-	E	ko:K02000	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	glycine betaine
HKANDMEF_02284	1.39e-176	sfsA	-	-	S	ko:K06206	-	ko00000	Belongs to the SfsA family
HKANDMEF_02285	2.6e-96	usp1	-	-	T	-	-	-	Universal stress protein family
HKANDMEF_02286	0.0	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
HKANDMEF_02287	7.73e-196	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HKANDMEF_02288	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
HKANDMEF_02289	7.09e-294	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
HKANDMEF_02290	0.0	-	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HKANDMEF_02291	2.16e-275	floL	-	-	S	ko:K07192	ko04910,map04910	ko00000,ko00001,ko03036,ko04131,ko04147	SPFH domain / Band 7 family
HKANDMEF_02292	7.64e-51	-	-	-	-	-	-	-	-
HKANDMEF_02293	2.23e-224	pfoSR	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
HKANDMEF_02294	3.03e-227	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HKANDMEF_02295	3.99e-278	aspC	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HKANDMEF_02296	3.74e-69	-	-	-	-	-	-	-	-
HKANDMEF_02297	9.39e-166	WQ51_05710	-	-	S	-	-	-	Mitochondrial biogenesis AIM24
HKANDMEF_02298	2.8e-94	-	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
HKANDMEF_02299	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HKANDMEF_02301	8.65e-182	mprF	2.3.2.3	-	M	ko:K07027,ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	lysyltransferase activity
HKANDMEF_02303	6.9e-262	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HKANDMEF_02304	6.42e-208	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
HKANDMEF_02305	3.26e-226	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HKANDMEF_02306	1.92e-283	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HKANDMEF_02307	9.96e-212	ysdB	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
HKANDMEF_02308	2.61e-280	ysdA	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HKANDMEF_02309	6.81e-86	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
HKANDMEF_02310	9.19e-209	CcmA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HKANDMEF_02311	1.28e-144	-	-	-	I	-	-	-	ABC-2 family transporter protein
HKANDMEF_02312	2.06e-187	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	reductase
HKANDMEF_02313	1.84e-260	ald1	1.4.1.1	-	C	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
HKANDMEF_02314	3.18e-240	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HKANDMEF_02315	2.56e-162	-	-	-	S	-	-	-	OPT oligopeptide transporter protein
HKANDMEF_02316	1.06e-262	-	-	-	S	-	-	-	OPT oligopeptide transporter protein
HKANDMEF_02317	8.34e-83	-	-	-	S	-	-	-	Coenzyme PQQ synthesis protein D (PqqD)
HKANDMEF_02318	0.0	pepD3	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HKANDMEF_02319	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
HKANDMEF_02320	0.0	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
HKANDMEF_02321	4.96e-127	-	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Bacterial regulatory proteins, tetR family
HKANDMEF_02322	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HKANDMEF_02323	0.0	bglP	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HKANDMEF_02324	2.51e-200	bglG4	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HKANDMEF_02325	0.0	msbA9	-	-	V	ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
HKANDMEF_02326	0.0	cydD1	-	-	CO	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
HKANDMEF_02327	3.15e-98	-	-	-	S	-	-	-	NusG domain II
HKANDMEF_02328	2.48e-52	-	-	-	L	ko:K07483	-	ko00000	Transposase and inactivated derivatives
HKANDMEF_02329	1.07e-203	-	-	-	L	-	-	-	Integrase core domain
HKANDMEF_02330	1.1e-155	-	-	-	S	-	-	-	CRISPR-associated protein (Cas_Csn2)
HKANDMEF_02331	2.84e-62	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HKANDMEF_02332	2.98e-216	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HKANDMEF_02333	0.0	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
HKANDMEF_02334	1.68e-183	-	-	-	-	-	-	-	-
HKANDMEF_02335	3.78e-275	-	-	-	S	-	-	-	Membrane
HKANDMEF_02336	6.76e-84	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
HKANDMEF_02337	6.43e-66	-	-	-	-	-	-	-	-
HKANDMEF_02338	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HKANDMEF_02339	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HKANDMEF_02340	2.5e-233	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
HKANDMEF_02341	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
HKANDMEF_02343	1.73e-305	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	pyrimidine-nucleoside phosphorylase
HKANDMEF_02344	1.86e-245	add	3.5.4.2, 3.5.4.4	-	F	ko:K01488,ko:K02029,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HKANDMEF_02345	6.98e-53	-	-	-	-	-	-	-	-
HKANDMEF_02346	1.22e-112	-	-	-	-	-	-	-	-
HKANDMEF_02347	6.71e-34	-	-	-	-	-	-	-	-
HKANDMEF_02348	1.72e-213	-	-	-	EG	-	-	-	EamA-like transporter family
HKANDMEF_02349	2.96e-145	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
HKANDMEF_02350	9.59e-101	usp5	-	-	T	-	-	-	universal stress protein
HKANDMEF_02351	3.25e-74	-	-	-	K	-	-	-	Helix-turn-helix domain
HKANDMEF_02352	6.37e-187	ptp3	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HKANDMEF_02353	6.69e-287	queG	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Domain of unknown function (DUF1730)
HKANDMEF_02354	1.54e-84	-	-	-	-	-	-	-	-
HKANDMEF_02355	2.27e-247	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
HKANDMEF_02356	7.09e-113	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
HKANDMEF_02357	5.77e-93	adhR	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HKANDMEF_02358	2.31e-110	-	-	-	C	-	-	-	Flavodoxin
HKANDMEF_02359	1.33e-253	adh2	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HKANDMEF_02360	2.75e-148	-	-	-	GM	-	-	-	NmrA-like family
HKANDMEF_02362	5.62e-132	-	-	-	Q	-	-	-	methyltransferase
HKANDMEF_02363	7.76e-143	-	-	-	T	-	-	-	Sh3 type 3 domain protein
HKANDMEF_02364	8.17e-153	-	-	-	F	-	-	-	glutamine amidotransferase
HKANDMEF_02365	6.35e-175	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2263)
HKANDMEF_02366	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
HKANDMEF_02367	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HKANDMEF_02368	8.38e-80	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
HKANDMEF_02369	2.04e-129	maf	-	-	D	ko:K06287	-	ko00000	nucleoside-triphosphate diphosphatase activity
HKANDMEF_02370	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HKANDMEF_02371	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HKANDMEF_02372	0.0	ydaO	-	-	E	-	-	-	amino acid
HKANDMEF_02373	1.31e-75	-	-	-	S	-	-	-	Domain of unknown function (DUF1827)
HKANDMEF_02374	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HKANDMEF_02375	1.7e-59	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HKANDMEF_02376	2.13e-143	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HKANDMEF_02377	1.01e-251	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HKANDMEF_02378	1.2e-238	-	-	-	-	-	-	-	-
HKANDMEF_02379	5.93e-204	-	-	-	V	ko:K01990,ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HKANDMEF_02380	4.97e-81	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
HKANDMEF_02381	1.1e-151	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HKANDMEF_02382	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
HKANDMEF_02383	3.12e-68	ptcB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HKANDMEF_02384	5.99e-243	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HKANDMEF_02385	8.44e-130	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
HKANDMEF_02386	3.82e-168	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
HKANDMEF_02387	8.43e-96	-	-	-	-	-	-	-	-
HKANDMEF_02388	2.42e-117	-	-	-	T	-	-	-	ECF transporter, substrate-specific component
HKANDMEF_02389	4.68e-232	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
HKANDMEF_02390	3.86e-185	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
HKANDMEF_02391	1.49e-192	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HKANDMEF_02392	7.92e-76	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
HKANDMEF_02393	2.28e-223	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HKANDMEF_02394	1.14e-69	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
HKANDMEF_02395	7.2e-151	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HKANDMEF_02396	2.95e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
HKANDMEF_02397	1.26e-139	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HKANDMEF_02398	7e-49	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HKANDMEF_02399	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HKANDMEF_02400	4.38e-118	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HKANDMEF_02401	9.05e-67	-	-	-	-	-	-	-	-
HKANDMEF_02402	8.53e-142	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
HKANDMEF_02403	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HKANDMEF_02404	3.3e-59	-	-	-	-	-	-	-	-
HKANDMEF_02405	1.49e-225	ccpB	-	-	K	-	-	-	lacI family
HKANDMEF_02406	0.0	prtB	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HKANDMEF_02407	7.22e-207	-	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HKANDMEF_02408	1.37e-74	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HKANDMEF_02409	7.23e-108	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HKANDMEF_02410	8.17e-285	mdtG	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
HKANDMEF_02411	3.64e-201	-	-	-	K	-	-	-	acetyltransferase
HKANDMEF_02412	3.45e-87	-	-	-	-	-	-	-	-
HKANDMEF_02413	4.33e-280	yceI	-	-	G	ko:K08369	-	ko00000,ko02000	Sugar (and other) transporter
HKANDMEF_02414	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HKANDMEF_02415	1.89e-158	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HKANDMEF_02416	6.87e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HKANDMEF_02417	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
HKANDMEF_02418	0.0	nylA	3.5.1.4	-	J	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	Belongs to the amidase family
HKANDMEF_02419	4.39e-89	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
HKANDMEF_02420	7.84e-123	yvqK	2.5.1.17	-	S	ko:K00798	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Cobalamin adenosyltransferase
HKANDMEF_02421	9.98e-128	-	-	-	S	ko:K16927	-	ko00000,ko00002,ko02000	ECF transporter, substrate-specific component
HKANDMEF_02422	4.31e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF4430)
HKANDMEF_02423	0.0	rtpR	1.17.4.2	-	F	ko:K00527	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	ribonucleoside-triphosphate reductase activity
HKANDMEF_02424	3.77e-102	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
HKANDMEF_02425	1.71e-205	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HKANDMEF_02426	2.29e-130	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HKANDMEF_02427	2.09e-30	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HKANDMEF_02428	4.4e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HKANDMEF_02429	1.13e-220	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
HKANDMEF_02430	2.44e-216	menA	2.5.1.74	-	M	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
HKANDMEF_02431	2.2e-252	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HKANDMEF_02432	4.15e-188	cad	-	-	S	ko:K20379	ko02024,map02024	ko00000,ko00001	FMN_bind
HKANDMEF_02433	0.0	ndh	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HKANDMEF_02434	4.76e-105	-	-	-	S	-	-	-	NusG domain II
HKANDMEF_02435	1.03e-127	hepA	2.5.1.30	-	S	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase component I
HKANDMEF_02436	3.28e-232	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HKANDMEF_02438	2.3e-158	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	Rossmann-like domain
HKANDMEF_02439	2.2e-250	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
HKANDMEF_02441	5.04e-127	yacP	-	-	S	ko:K06962	-	ko00000	YacP-like NYN domain
HKANDMEF_02442	9.39e-183	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HKANDMEF_02443	2.39e-98	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HKANDMEF_02444	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HKANDMEF_02445	0.0	loxD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
HKANDMEF_02446	2.65e-139	-	-	-	-	-	-	-	-
HKANDMEF_02448	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HKANDMEF_02449	3.45e-239	XK27_10475	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HKANDMEF_02450	3.15e-154	rpiA1	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
HKANDMEF_02451	1.73e-182	-	-	-	K	-	-	-	SIS domain
HKANDMEF_02452	8.77e-147	yhfC	-	-	S	-	-	-	Putative membrane peptidase family (DUF2324)
HKANDMEF_02453	2.27e-225	-	-	-	S	-	-	-	Membrane
HKANDMEF_02454	9.18e-83	-	-	-	K	-	-	-	helix_turn_helix gluconate operon transcriptional repressor
HKANDMEF_02455	3.39e-227	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HKANDMEF_02456	6.11e-186	natA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HKANDMEF_02457	1.72e-169	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
HKANDMEF_02458	5.59e-174	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
HKANDMEF_02459	5.17e-290	inlJ	-	-	M	-	-	-	MucBP domain
HKANDMEF_02460	5.79e-172	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HKANDMEF_02461	6.18e-206	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKANDMEF_02462	2.54e-211	-	-	-	K	-	-	-	sequence-specific DNA binding
HKANDMEF_02463	5.49e-261	yacL	-	-	S	-	-	-	domain protein
HKANDMEF_02464	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HKANDMEF_02465	4.85e-130	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTPase
HKANDMEF_02466	1.22e-67	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
HKANDMEF_02467	5.93e-93	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
HKANDMEF_02468	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
HKANDMEF_02469	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HKANDMEF_02470	1.97e-256	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
HKANDMEF_02471	3.84e-279	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HKANDMEF_02472	5.79e-214	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HKANDMEF_02473	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HKANDMEF_02474	0.0	ppdK	2.7.9.1	-	G	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the PEP-utilizing enzyme family
HKANDMEF_02475	3.68e-136	ccpN	-	-	K	-	-	-	Domain in cystathionine beta-synthase and other proteins.
HKANDMEF_02476	1.19e-158	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HKANDMEF_02477	4.71e-263	-	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
HKANDMEF_02478	5.25e-61	-	-	-	-	-	-	-	-
HKANDMEF_02479	2.08e-265	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HKANDMEF_02480	1.59e-28	yhjA	-	-	K	-	-	-	CsbD-like
HKANDMEF_02481	2.28e-293	-	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
HKANDMEF_02482	3.02e-275	-	-	-	EGP	ko:K08196	-	ko00000,ko02000	Major Facilitator
HKANDMEF_02483	1.45e-180	udp	2.4.2.3	-	F	ko:K00757	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Phosphorylase superfamily
HKANDMEF_02484	6.53e-272	-	-	-	EGP	ko:K08196	-	ko00000,ko02000	Major Facilitator
HKANDMEF_02485	9.8e-247	-	-	-	KT	ko:K02647	-	ko00000,ko03000	Purine catabolism regulatory protein-like family
HKANDMEF_02487	1.5e-44	-	-	-	-	-	-	-	-
HKANDMEF_02488	6.09e-53	-	-	-	-	-	-	-	-
HKANDMEF_02489	4.23e-287	-	-	-	EGP	-	-	-	Transmembrane secretion effector
HKANDMEF_02490	5.68e-280	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HKANDMEF_02491	4.65e-192	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HKANDMEF_02493	2.57e-55	-	-	-	-	-	-	-	-
HKANDMEF_02494	1.38e-295	-	-	-	S	-	-	-	Membrane
HKANDMEF_02495	2.81e-192	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
HKANDMEF_02496	0.0	-	-	-	M	-	-	-	Cna protein B-type domain
HKANDMEF_02497	5.21e-310	-	-	-	-	-	-	-	-
HKANDMEF_02498	0.0	-	-	-	M	-	-	-	domain protein
HKANDMEF_02499	8.99e-133	-	-	-	-	-	-	-	-
HKANDMEF_02500	9.31e-294	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
HKANDMEF_02501	1.2e-263	-	-	-	S	-	-	-	Protein of unknown function (DUF2974)
HKANDMEF_02502	3.71e-146	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HKANDMEF_02503	8.68e-74	padR	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
HKANDMEF_02504	1.93e-80	-	-	-	-	-	-	-	-
HKANDMEF_02505	2.2e-178	-	-	-	-	-	-	-	-
HKANDMEF_02506	6.69e-61	-	-	-	S	-	-	-	Enterocin A Immunity
HKANDMEF_02507	2.22e-60	-	-	-	S	-	-	-	Enterocin A Immunity
HKANDMEF_02508	3.61e-61	spiA	-	-	K	-	-	-	TRANSCRIPTIONal
HKANDMEF_02509	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
HKANDMEF_02511	5.75e-72	-	-	-	-	-	-	-	-
HKANDMEF_02512	5.05e-313	mesE	-	-	M	ko:K12293,ko:K20345	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	Transport protein ComB
HKANDMEF_02513	0.0	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HKANDMEF_02514	2.95e-50	-	-	-	V	ko:K06147,ko:K06148,ko:K20344	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko02000	protein secretion by the type I secretion system
HKANDMEF_02517	1.35e-174	-	2.7.13.3	-	T	ko:K02476,ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	protein histidine kinase activity
HKANDMEF_02518	7.99e-184	plnD	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HKANDMEF_02521	1.27e-15	-	-	-	-	-	-	-	-
HKANDMEF_02525	1.66e-188	-	-	-	S	-	-	-	CAAX protease self-immunity
HKANDMEF_02527	5.62e-75	-	-	-	-	-	-	-	-
HKANDMEF_02528	1.66e-05	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
HKANDMEF_02529	1.18e-72	-	-	-	S	-	-	-	Enterocin A Immunity
HKANDMEF_02530	7.86e-138	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HKANDMEF_02534	8.37e-231	ydhF	-	-	S	-	-	-	Aldo keto reductase
HKANDMEF_02535	3.51e-166	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HKANDMEF_02536	1.98e-278	yqiG	-	-	C	-	-	-	Oxidoreductase
HKANDMEF_02537	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HKANDMEF_02538	1.88e-174	-	-	-	-	-	-	-	-
HKANDMEF_02539	6.42e-28	-	-	-	-	-	-	-	-
HKANDMEF_02540	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HKANDMEF_02541	0.0	atp2C1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HKANDMEF_02542	1.14e-72	-	-	-	-	-	-	-	-
HKANDMEF_02543	4.42e-306	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HKANDMEF_02544	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
HKANDMEF_02545	1.53e-35	-	-	-	-	-	-	-	-
HKANDMEF_02546	2.22e-144	-	-	-	P	-	-	-	Cation efflux family
HKANDMEF_02547	1.23e-69	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
HKANDMEF_02548	6.58e-226	mntA	-	-	P	ko:K19975,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HKANDMEF_02549	1.07e-187	mtsB	-	-	U	ko:K19972,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
HKANDMEF_02550	3.38e-170	-	3.6.3.35	-	P	ko:K19973	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HKANDMEF_02551	0.0	aldA	1.2.1.21, 1.2.1.22	-	C	ko:K07248	ko00620,ko00630,ko01120,map00620,map00630,map01120	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family
HKANDMEF_02552	2.9e-56	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HKANDMEF_02553	4.82e-226	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HKANDMEF_02554	6.75e-215	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HKANDMEF_02555	2.83e-152	-	-	-	GM	-	-	-	NmrA-like family
HKANDMEF_02556	5.94e-148	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
HKANDMEF_02557	7.04e-102	-	-	-	-	-	-	-	-
HKANDMEF_02558	0.0	-	-	-	M	-	-	-	domain protein
HKANDMEF_02559	1.26e-212	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HKANDMEF_02560	2.1e-27	-	-	-	-	-	-	-	-
HKANDMEF_02561	8.26e-104	-	-	-	-	-	-	-	-
HKANDMEF_02563	0.0	-	-	-	L	-	-	-	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HKANDMEF_02564	6.39e-73	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HKANDMEF_02565	1.58e-91	crcB1	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HKANDMEF_02567	1.72e-49	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	phosphopyruvate hydratase activity
HKANDMEF_02568	1.99e-212	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
HKANDMEF_02569	1.49e-178	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HKANDMEF_02570	2.46e-174	phnB	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKANDMEF_02571	1.97e-188	ptxC	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKANDMEF_02572	4.82e-226	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HKANDMEF_02573	6.58e-227	ssuA	-	-	P	ko:K02051,ko:K15553	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	NMT1-like family
HKANDMEF_02574	0.0	-	6.2.1.48	-	IQ	ko:K02182	-	ko00000,ko01000	AMP-binding enzyme C-terminal domain
HKANDMEF_02575	1.2e-302	-	-	-	I	-	-	-	Acyltransferase family
HKANDMEF_02576	1.17e-154	ssuB	-	-	P	ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HKANDMEF_02577	1.02e-192	ssuC	-	-	U	ko:K15554	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKANDMEF_02578	7.94e-175	XK27_06950	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HKANDMEF_02579	2.2e-175	XK27_06945	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HKANDMEF_02580	2.04e-175	-	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HKANDMEF_02581	1.17e-123	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
HKANDMEF_02582	1.28e-12	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
HKANDMEF_02583	9.26e-146	-	-	-	-	-	-	-	-
HKANDMEF_02584	1.29e-74	-	-	-	-	-	-	-	-
HKANDMEF_02585	8.98e-86	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
HKANDMEF_02586	2.98e-104	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HKANDMEF_02587	1.46e-140	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKANDMEF_02588	2.61e-238	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HKANDMEF_02589	3.14e-165	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HKANDMEF_02590	1.5e-44	-	-	-	-	-	-	-	-
HKANDMEF_02591	3.24e-171	tipA	-	-	K	-	-	-	TipAS antibiotic-recognition domain
HKANDMEF_02592	1.39e-178	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HKANDMEF_02593	1.13e-181	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HKANDMEF_02594	4.71e-203	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HKANDMEF_02595	1.15e-197	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HKANDMEF_02596	9.02e-154	-	-	-	-	-	-	-	-
HKANDMEF_02597	5.46e-81	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HKANDMEF_02598	1.26e-218	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKANDMEF_02599	3.82e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HKANDMEF_02600	5.37e-76	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HKANDMEF_02601	6.38e-20	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
HKANDMEF_02602	4.15e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HKANDMEF_02603	1.11e-156	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HKANDMEF_02604	4.24e-305	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HKANDMEF_02605	4.07e-92	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HKANDMEF_02606	2.6e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
HKANDMEF_02607	5.74e-109	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HKANDMEF_02608	1.62e-76	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HKANDMEF_02609	2.61e-123	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HKANDMEF_02610	1.32e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HKANDMEF_02611	8.67e-124	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HKANDMEF_02612	4.1e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HKANDMEF_02613	1.73e-77	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HKANDMEF_02614	5.93e-55	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HKANDMEF_02615	3.55e-33	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
HKANDMEF_02616	1.38e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HKANDMEF_02617	2.8e-151	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HKANDMEF_02618	4.5e-73	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HKANDMEF_02619	5.26e-63	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HKANDMEF_02620	7.23e-201	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HKANDMEF_02621	1.02e-61	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HKANDMEF_02622	1.98e-140	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
HKANDMEF_02623	4.01e-146	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HKANDMEF_02624	4.46e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
HKANDMEF_02625	3.63e-90	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
HKANDMEF_02626	2.38e-138	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	C-terminal domain of 1-Cys peroxiredoxin
HKANDMEF_02627	3.54e-257	-	-	-	K	-	-	-	WYL domain
HKANDMEF_02628	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HKANDMEF_02629	2.4e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HKANDMEF_02630	1.11e-92	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HKANDMEF_02631	0.0	-	-	-	M	-	-	-	domain protein
HKANDMEF_02632	1.47e-46	-	3.4.23.43	-	-	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	-
HKANDMEF_02633	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKANDMEF_02634	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKANDMEF_02635	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HKANDMEF_02636	4.32e-105	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
HKANDMEF_02647	5.19e-90	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
HKANDMEF_02650	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HKANDMEF_02651	5.32e-242	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HKANDMEF_02652	5.11e-209	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HKANDMEF_02653	1.59e-210	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HKANDMEF_02655	4.22e-244	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
HKANDMEF_02656	1.18e-250	-	-	-	S	-	-	-	Protein of unknown function C-terminal (DUF3324)
HKANDMEF_02657	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
HKANDMEF_02658	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HKANDMEF_02659	1.38e-125	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
HKANDMEF_02660	2.68e-310	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HKANDMEF_02661	1.17e-105	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
HKANDMEF_02662	7.17e-87	divIC	-	-	D	ko:K05589,ko:K13052	-	ko00000,ko03036	cell cycle
HKANDMEF_02663	1.99e-53	yabO	-	-	J	-	-	-	S4 domain protein
HKANDMEF_02664	0.0	yabM	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HKANDMEF_02665	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HKANDMEF_02666	4.28e-131	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HKANDMEF_02667	5.04e-232	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HKANDMEF_02668	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
HKANDMEF_02669	4.14e-126	padR	-	-	K	-	-	-	Transcriptional regulator PadR-like family
HKANDMEF_02670	0.0	-	-	-	S	ko:K01421	-	ko00000	ABC-2 family transporter protein
HKANDMEF_02671	2.45e-150	-	-	-	S	-	-	-	Flavodoxin-like fold
HKANDMEF_02672	3.08e-124	-	-	-	S	-	-	-	(CBS) domain
HKANDMEF_02673	1.02e-169	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
HKANDMEF_02674	0.0	gltD	1.4.1.13, 1.4.1.14	-	E	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
HKANDMEF_02675	0.0	gltA	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	GXGXG motif
HKANDMEF_02676	1.39e-112	queT	-	-	S	-	-	-	QueT transporter
HKANDMEF_02677	5.68e-83	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
HKANDMEF_02678	1.9e-43	-	-	-	-	-	-	-	-
HKANDMEF_02679	2.8e-278	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HKANDMEF_02680	2.63e-82	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HKANDMEF_02681	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HKANDMEF_02682	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HKANDMEF_02683	2.07e-188	-	-	-	-	-	-	-	-
HKANDMEF_02684	3.18e-161	-	-	-	S	-	-	-	Tetratricopeptide repeat
HKANDMEF_02685	2.61e-163	-	-	-	-	-	-	-	-
HKANDMEF_02686	2.29e-87	-	-	-	-	-	-	-	-
HKANDMEF_02687	2.28e-57	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
HKANDMEF_02688	1.64e-300	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HKANDMEF_02689	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HKANDMEF_02690	3.42e-202	ybbB	-	-	S	-	-	-	Protein of unknown function (DUF1211)
HKANDMEF_02691	1.15e-111	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HKANDMEF_02692	4.23e-104	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
HKANDMEF_02693	2.07e-202	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	biotin lipoate A B protein ligase
HKANDMEF_02694	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
HKANDMEF_02695	3.75e-40	mutT	3.5.4.33, 3.6.1.13, 3.6.1.55	-	L	ko:K01515,ko:K03574,ko:K11991	ko00230,map00230	ko00000,ko00001,ko01000,ko03016,ko03400	nUDIX hydrolase
HKANDMEF_02696	2.14e-237	-	-	-	S	-	-	-	DUF218 domain
HKANDMEF_02697	1.31e-77	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HKANDMEF_02698	1.68e-104	-	-	-	E	-	-	-	glutamate:sodium symporter activity
HKANDMEF_02699	1.32e-74	nudA	-	-	S	-	-	-	ASCH
HKANDMEF_02700	1.81e-35	-	-	-	-	-	-	-	-
HKANDMEF_02701	2.2e-225	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HKANDMEF_02702	3.29e-299	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HKANDMEF_02703	1.79e-286	ysaA	-	-	V	-	-	-	RDD family
HKANDMEF_02704	1.01e-193	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
HKANDMEF_02705	2.24e-155	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKANDMEF_02706	8.36e-158	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
HKANDMEF_02707	1.4e-205	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
HKANDMEF_02708	6.63e-232	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HKANDMEF_02709	4.13e-51	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
HKANDMEF_02710	1.75e-203	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HKANDMEF_02711	6.78e-130	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HKANDMEF_02712	9.1e-190	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
HKANDMEF_02713	2.57e-104	manR	2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204	-	G	ko:K02538,ko:K02768,ko:K02769,ko:K02770,ko:K02773,ko:K02806,ko:K02821,ko:K03491,ko:K11201,ko:K20112	ko00051,ko00052,ko00053,ko01100,ko01120,ko02060,map00051,map00052,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000,ko03000	phosphoenolpyruvate-dependent sugar phosphotransferase system
HKANDMEF_02714	1.35e-239	lacD	4.1.2.40	-	G	ko:K01635	ko00052,ko01100,ko02024,map00052,map01100,map02024	ko00000,ko00001,ko01000	Belongs to the aldolase LacD family
HKANDMEF_02715	1.49e-221	yqhA	-	-	G	-	-	-	Aldose 1-epimerase
HKANDMEF_02716	8.65e-162	-	-	-	T	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HKANDMEF_02717	5.31e-211	-	-	-	T	-	-	-	GHKL domain
HKANDMEF_02718	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HKANDMEF_02719	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HKANDMEF_02720	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HKANDMEF_02721	4.11e-223	pepI	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HKANDMEF_02722	1.25e-197	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
HKANDMEF_02723	1.09e-118	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
HKANDMEF_02724	3.11e-218	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HKANDMEF_02725	9.14e-139	yiiE	-	-	S	-	-	-	Protein of unknown function (DUF1211)
HKANDMEF_02726	5.67e-165	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	Sir2 family
HKANDMEF_02727	6.41e-24	-	-	-	-	-	-	-	-
HKANDMEF_02728	5.59e-220	-	-	-	-	-	-	-	-
HKANDMEF_02730	3.21e-125	yxkA	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
HKANDMEF_02731	4.7e-50	-	-	-	-	-	-	-	-
HKANDMEF_02732	4.34e-196	ypuA	-	-	S	-	-	-	Protein of unknown function (DUF1002)
HKANDMEF_02733	2.57e-223	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HKANDMEF_02734	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HKANDMEF_02735	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HKANDMEF_02736	1.74e-224	ydhF	-	-	S	-	-	-	Aldo keto reductase
HKANDMEF_02738	2.82e-196	-	-	-	Q	-	-	-	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
HKANDMEF_02739	2.76e-120	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
HKANDMEF_02740	9.66e-307	dinF	-	-	V	-	-	-	MatE
HKANDMEF_02741	8.78e-158	-	-	-	S	ko:K06872	-	ko00000	TPM domain
HKANDMEF_02742	8.42e-135	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
HKANDMEF_02743	1.48e-246	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HKANDMEF_02744	5.94e-262	-	-	-	V	-	-	-	efflux transmembrane transporter activity
HKANDMEF_02745	1.95e-225	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
HKANDMEF_02747	0.0	gshR	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
HKANDMEF_02748	6.07e-225	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HKANDMEF_02749	0.0	choS	-	-	EM	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HKANDMEF_02751	0.0	-	-	-	L	-	-	-	DNA helicase
HKANDMEF_02752	2.93e-195	rlrG	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
HKANDMEF_02753	1.6e-222	ydiA	-	-	P	ko:K11041	ko05150,map05150	ko00000,ko00001,ko02042	Voltage-dependent anion channel
HKANDMEF_02754	5.68e-148	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HKANDMEF_02756	3.62e-149	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HKANDMEF_02757	1.91e-93	-	-	-	K	-	-	-	MarR family
HKANDMEF_02758	0.0	uvrA3	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC
HKANDMEF_02759	7.61e-247	yghZ	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
HKANDMEF_02760	5.86e-187	-	-	-	S	-	-	-	hydrolase
HKANDMEF_02761	4.04e-79	-	-	-	-	-	-	-	-
HKANDMEF_02762	4.9e-17	-	-	-	-	-	-	-	-
HKANDMEF_02763	3.55e-146	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
HKANDMEF_02764	1.63e-163	gpmB	-	-	G	ko:K15640	-	ko00000	Phosphoglycerate mutase family
HKANDMEF_02765	5.08e-197	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HKANDMEF_02766	1.38e-117	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HKANDMEF_02767	1.08e-213	-	-	-	K	-	-	-	LysR substrate binding domain
HKANDMEF_02768	6.04e-291	-	-	-	EK	-	-	-	Aminotransferase, class I
HKANDMEF_02769	0.0	-	-	-	EGP	-	-	-	Major Facilitator
HKANDMEF_02770	8.61e-143	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKANDMEF_02771	2.13e-246	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HKANDMEF_02772	4.42e-154	ydfK	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
HKANDMEF_02773	5.24e-116	-	-	-	-	-	-	-	-
HKANDMEF_02774	0.0	fruC	2.7.1.202	-	GT	ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKANDMEF_02775	1.88e-223	fruK-1	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
HKANDMEF_02776	2.36e-167	rpl	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HKANDMEF_02777	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HKANDMEF_02778	5.44e-175	-	-	-	K	-	-	-	UTRA domain
HKANDMEF_02779	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
HKANDMEF_02780	1.72e-216	-	2.7.1.191	-	G	ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HKANDMEF_02781	9.8e-169	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
HKANDMEF_02782	2.84e-192	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
HKANDMEF_02783	5.34e-64	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
HKANDMEF_02784	5.16e-66	ptcB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HKANDMEF_02785	0.0	bgl	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HKANDMEF_02786	1.77e-203	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HKANDMEF_02787	0.0	-	-	-	S	ko:K09704	-	ko00000	Metal-independent alpha-mannosidase (GH125)
HKANDMEF_02788	0.0	mngB	3.2.1.170	GH38	G	ko:K15524	-	ko00000,ko01000	Glycosyl hydrolases family 38 N-terminal domain
HKANDMEF_02789	1.54e-307	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKANDMEF_02790	1.9e-173	-	-	-	K	ko:K03492	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
HKANDMEF_02792	3.7e-176	-	4.1.2.17	-	G	ko:K01628	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Class II Aldolase and Adducin N-terminal domain
HKANDMEF_02794	0.0	pts36C	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HKANDMEF_02795	4.54e-70	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HKANDMEF_02796	1.89e-110	pts36A	2.7.1.200	-	G	ko:K02773	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKANDMEF_02797	1.62e-186	rdrB	-	-	K	ko:K02444,ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
HKANDMEF_02798	4.06e-209	-	-	-	J	-	-	-	Methyltransferase domain
HKANDMEF_02799	0.0	-	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HKANDMEF_02802	3.65e-46	-	-	-	M	-	-	-	Right handed beta helix region
HKANDMEF_02803	0.0	-	-	-	M	-	-	-	Right handed beta helix region
HKANDMEF_02804	3.76e-96	-	-	-	-	-	-	-	-
HKANDMEF_02805	0.0	-	-	-	M	-	-	-	Heparinase II/III N-terminus
HKANDMEF_02807	5.89e-108	-	-	-	G	ko:K02744	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HKANDMEF_02808	8.63e-185	agaD	-	-	G	ko:K02747	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
HKANDMEF_02809	6.84e-186	-	-	-	G	ko:K02746	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
HKANDMEF_02810	1.72e-114	-	-	-	G	ko:K02745	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HKANDMEF_02811	8.01e-301	ugl	3.2.1.180	GH88	S	ko:K18581	-	ko00000,ko01000	Glycosyl Hydrolase Family 88
HKANDMEF_02812	1.65e-205	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HKANDMEF_02813	1.1e-179	-	-	-	K	-	-	-	Bacterial transcriptional regulator
HKANDMEF_02814	4.76e-212	kduI	5.3.1.17	-	G	ko:K01815	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
HKANDMEF_02815	6.38e-193	kduD	1.1.1.127	-	IQ	ko:K00065	ko00040,map00040	ko00000,ko00001,ko01000	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HKANDMEF_02816	2.32e-153	eda	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	KDPG and KHG aldolase
HKANDMEF_02817	3.36e-248	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	pfkB family carbohydrate kinase
HKANDMEF_02818	4.7e-156	alkD	-	-	L	-	-	-	DNA alkylation repair enzyme
HKANDMEF_02819	8.71e-164	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HKANDMEF_02820	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HKANDMEF_02821	2.46e-221	ykoT	-	-	M	-	-	-	Glycosyl transferase family 2
HKANDMEF_02822	1.56e-154	-	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	phosphatase
HKANDMEF_02823	8.38e-152	-	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
HKANDMEF_02824	1.8e-316	kinE	-	-	T	-	-	-	Histidine kinase
HKANDMEF_02825	1.97e-162	llrE	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
HKANDMEF_02826	0.0	-	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase C-terminal domain
HKANDMEF_02827	0.0	-	2.7.1.199, 2.7.1.208	-	G	ko:K02790,ko:K02791	ko00010,ko00500,ko00520,ko02060,map00010,map00500,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HKANDMEF_02828	0.0	hylB	4.2.2.1	PL8	N	ko:K01727	-	ko00000,ko01000	Polysaccharide lyase family 8, N terminal alpha-helical domain
HKANDMEF_02829	0.0	-	-	-	-	-	-	-	-
HKANDMEF_02830	1.72e-242	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
HKANDMEF_02831	4.77e-89	-	-	-	-	-	-	-	-
HKANDMEF_02833	3.3e-144	-	-	-	-	-	-	-	-
HKANDMEF_02834	6.42e-112	-	-	-	-	-	-	-	-
HKANDMEF_02835	2.49e-182	-	-	-	K	-	-	-	M protein trans-acting positive regulator
HKANDMEF_02836	2.5e-174	-	-	-	L	-	-	-	Helix-turn-helix domain
HKANDMEF_02837	2.46e-215	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HKANDMEF_02838	2.49e-167	mga	-	-	K	ko:K02538	-	ko00000,ko03000	transcriptional antiterminator
HKANDMEF_02839	3.39e-156	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HKANDMEF_02840	2.57e-109	ptbA	2.7.1.208	-	G	ko:K02755,ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HKANDMEF_02841	3.33e-265	-	-	-	S	-	-	-	DUF218 domain
HKANDMEF_02842	5.63e-177	-	4.1.2.14	-	S	ko:K17463	ko00030,ko01100,ko01120,map00030,map01100,map01120	ko00000,ko00001,ko00002,ko01000	KDGP aldolase
HKANDMEF_02843	2.62e-261	selA	2.9.1.1	-	H	ko:K01042	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko01000	L-seryl-tRNA selenium transferase
HKANDMEF_02844	3.82e-278	dho	3.5.2.3	-	S	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Amidohydrolase family
HKANDMEF_02845	3.79e-155	-	-	-	S	-	-	-	Domain of unknown function (DUF4310)
HKANDMEF_02846	4.1e-177	-	-	-	S	-	-	-	Domain of unknown function (DUF4311)
HKANDMEF_02847	1.1e-76	-	-	-	S	-	-	-	Domain of unknown function (DUF4312)
HKANDMEF_02848	2.66e-53	-	-	-	S	-	-	-	Glycine-rich SFCGS
HKANDMEF_02849	1.82e-74	-	-	-	S	-	-	-	PRD domain
HKANDMEF_02850	0.0	-	-	-	K	-	-	-	Mga helix-turn-helix domain
HKANDMEF_02851	8.74e-161	-	-	-	H	-	-	-	Pfam:Transaldolase
HKANDMEF_02852	2.24e-84	-	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
HKANDMEF_02853	3.58e-262	srlE	2.7.1.198	-	G	ko:K02782,ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Sorbitol phosphotransferase enzyme II N-terminus
HKANDMEF_02854	5.81e-131	srlA	-	-	G	ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko02000	PTS system enzyme II sorbitol-specific factor
HKANDMEF_02855	2.63e-115	srlM1	-	-	K	-	-	-	Glucitol operon activator protein (GutM)
HKANDMEF_02856	0.0	srlM	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
HKANDMEF_02857	4.13e-185	srlD2	1.1.1.140	-	IQ	ko:K00068	ko00051,map00051	ko00000,ko00001,ko01000	NAD dependent epimerase/dehydratase family
HKANDMEF_02858	1.57e-177	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
HKANDMEF_02859	2.51e-194	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HKANDMEF_02860	1.53e-212	sga	5.1.3.22	-	G	ko:K03079	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Xylose isomerase-like TIM barrel
HKANDMEF_02861	8.64e-178	-	-	-	K	-	-	-	DeoR C terminal sensor domain
HKANDMEF_02862	3.17e-149	ulaD	4.1.1.85, 4.1.2.43	-	G	ko:K03078,ko:K08093	ko00030,ko00040,ko00053,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00040,map00053,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Orotidine 5'-phosphate decarboxylase / HUMPS family
HKANDMEF_02863	3.36e-61	sgaB	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HKANDMEF_02864	0.0	sgaT	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HKANDMEF_02865	4.89e-105	-	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKANDMEF_02866	4.59e-275	ulaG	-	-	S	ko:K03476	ko00053,ko01100,ko01120,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Beta-lactamase superfamily domain
HKANDMEF_02867	2.92e-162	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HKANDMEF_02868	1.1e-254	-	1.1.1.14	-	C	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
HKANDMEF_02869	4.26e-91	-	-	-	G	-	-	-	DeoC/LacD family aldolase
HKANDMEF_02870	3.93e-58	-	4.1.2.13	-	G	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	lyase activity
HKANDMEF_02871	1.15e-154	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
HKANDMEF_02872	1.29e-201	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
HKANDMEF_02873	1.95e-172	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
HKANDMEF_02874	2.79e-107	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HKANDMEF_02875	1.23e-95	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HKANDMEF_02876	3.07e-263	-	1.1.1.405	-	E	ko:K05352	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
HKANDMEF_02877	1.67e-173	-	-	-	K	-	-	-	DeoR C terminal sensor domain
HKANDMEF_02878	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
HKANDMEF_02879	5.08e-207	-	-	-	GK	-	-	-	ROK family
HKANDMEF_02880	6.65e-234	asnA2	3.5.1.1	-	E	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
HKANDMEF_02881	0.0	-	-	-	E	-	-	-	Peptidase family M20/M25/M40
HKANDMEF_02882	2.59e-170	-	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
HKANDMEF_02883	0.0	-	4.1.1.12	-	E	ko:K09758	ko00250,ko00270,ko01100,ko01230,map00250,map00270,map01100,map01230	ko00000,ko00001,ko01000	Aminotransferase
HKANDMEF_02884	1.67e-272	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
HKANDMEF_02885	2.07e-265	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
HKANDMEF_02886	1.07e-93	-	-	-	S	-	-	-	Domain of unknown function (DUF4428)
HKANDMEF_02887	0.0	-	2.7.1.17, 2.7.1.53	-	G	ko:K00854,ko:K00880	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the FGGY kinase family
HKANDMEF_02888	6.91e-261	-	1.1.1.14	-	C	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
HKANDMEF_02889	1.34e-199	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
HKANDMEF_02890	3.52e-176	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
HKANDMEF_02891	5.64e-107	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HKANDMEF_02892	1.03e-92	ahaA	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HKANDMEF_02893	0.0	-	-	-	K	ko:K03491	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKANDMEF_02894	1.72e-242	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
HKANDMEF_02895	2.4e-20	licR	-	-	G	ko:K03491	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKANDMEF_02896	3.46e-207	-	-	-	G	-	-	-	Fructose-bisphosphate aldolase class-II
HKANDMEF_02897	0.0	-	-	-	G	-	-	-	FGGY family of carbohydrate kinases, C-terminal domain
HKANDMEF_02898	0.0	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HKANDMEF_02899	9.89e-64	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HKANDMEF_02900	6.52e-103	-	2.7.1.200	-	GT	ko:K02773	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKANDMEF_02901	2.63e-206	-	-	-	G	-	-	-	Fructose-bisphosphate aldolase class-II
HKANDMEF_02902	1.97e-173	farR	-	-	K	-	-	-	Helix-turn-helix domain
HKANDMEF_02903	1.66e-116	-	-	-	M	ko:K03828	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HKANDMEF_02904	2.16e-132	laaE	-	-	K	-	-	-	Transcriptional regulator PadR-like family
HKANDMEF_02905	0.0	chaT1	-	-	U	ko:K03446	-	ko00000,ko00002,ko02000	the major facilitator superfamily
HKANDMEF_02906	2.75e-116	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HKANDMEF_02907	3.62e-121	yveA	-	-	Q	-	-	-	Isochorismatase family
HKANDMEF_02908	9.53e-76	ps105	-	-	-	-	-	-	-
HKANDMEF_02910	5.38e-125	-	-	-	K	-	-	-	Helix-turn-helix domain
HKANDMEF_02911	3.37e-140	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
HKANDMEF_02912	3.87e-97	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HKANDMEF_02913	0.0	ugpB	-	-	G	ko:K05813	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HKANDMEF_02914	2.92e-192	ugpE	-	-	G	ko:K05815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HKANDMEF_02915	3.19e-211	-	-	-	P	ko:K05814	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type sugar transport systems, permease components
HKANDMEF_02916	7.33e-271	ugpC	3.6.3.20	-	E	ko:K05816,ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the ABC transporter superfamily
HKANDMEF_02917	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HKANDMEF_02918	1.89e-139	pncA	-	-	Q	-	-	-	Isochorismatase family
HKANDMEF_02919	3.28e-175	-	-	-	F	-	-	-	NUDIX domain
HKANDMEF_02920	1.45e-187	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
HKANDMEF_02921	9.61e-247	ykfB	5.1.1.20	-	M	ko:K19802	-	ko00000,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
HKANDMEF_02922	1.13e-251	-	-	-	V	-	-	-	Beta-lactamase
HKANDMEF_02923	1.43e-197	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HKANDMEF_02924	1.58e-211	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HKANDMEF_02925	1.67e-105	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HKANDMEF_02926	1.56e-192	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
HKANDMEF_02927	8.76e-177	XK27_08455	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
HKANDMEF_02928	1.06e-259	-	-	-	S	-	-	-	endonuclease exonuclease phosphatase family protein
HKANDMEF_02929	2.28e-220	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
HKANDMEF_02930	1.18e-134	-	-	-	Q	-	-	-	Methyltransferase
HKANDMEF_02931	2.16e-68	sugE	-	-	U	ko:K11741	-	ko00000,ko02000	Multidrug resistance protein
HKANDMEF_02932	2.69e-22	-	-	-	-	-	-	-	-
HKANDMEF_02933	2.45e-59	-	-	-	I	-	-	-	carboxylic ester hydrolase activity
HKANDMEF_02934	3.22e-65	-	-	-	S	-	-	-	alpha beta
HKANDMEF_02935	3.81e-84	-	-	-	S	-	-	-	Protein of unknown function (DUF1648)
HKANDMEF_02936	5.44e-174	-	-	-	S	-	-	-	-acetyltransferase
HKANDMEF_02937	1.17e-121	yfbM	-	-	K	-	-	-	FR47-like protein
HKANDMEF_02938	2.42e-122	-	-	-	E	-	-	-	HAD-hyrolase-like
HKANDMEF_02939	4.93e-244	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
HKANDMEF_02940	8.05e-180	ptp1	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HKANDMEF_02941	1.7e-122	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HKANDMEF_02942	5.73e-110	yiaC	-	-	K	ko:K03826	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HKANDMEF_02943	2.61e-105	-	-	-	K	ko:K03830	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HKANDMEF_02944	8.99e-300	-	-	-	K	-	-	-	Putative DNA-binding domain
HKANDMEF_02945	1.06e-163	tnp1216	-	-	L	ko:K07498	-	ko00000	DDE domain
HKANDMEF_02946	1.74e-106	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HKANDMEF_02947	9.37e-255	ysdE	-	-	P	-	-	-	Citrate transporter
HKANDMEF_02948	8.69e-91	-	-	-	-	-	-	-	-
HKANDMEF_02949	0.0	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Peptidase dimerisation domain
HKANDMEF_02950	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HKANDMEF_02952	2.96e-134	-	-	-	-	-	-	-	-
HKANDMEF_02953	0.0	cadA	-	-	P	-	-	-	P-type ATPase
HKANDMEF_02954	2.19e-100	hsp3	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HKANDMEF_02955	2.35e-92	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
HKANDMEF_02956	1.7e-284	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
HKANDMEF_02958	4.32e-196	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
HKANDMEF_02959	1.05e-182	yycI	-	-	S	-	-	-	YycH protein
HKANDMEF_02960	0.0	yycH	-	-	S	-	-	-	YycH protein
HKANDMEF_02961	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HKANDMEF_02962	3.03e-168	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HKANDMEF_02963	1.06e-157	-	1.11.1.10	-	S	ko:K00433	-	ko00000,ko01000	Alpha/beta hydrolase family
HKANDMEF_02964	0.0	arpJ	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HKANDMEF_02965	1.39e-299	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
HKANDMEF_02966	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
HKANDMEF_02967	4.78e-273	ybhE	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
HKANDMEF_02968	9.09e-97	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
HKANDMEF_02969	0.0	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKANDMEF_02970	1.97e-168	gntR	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
HKANDMEF_02971	5.01e-69	pts20B	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HKANDMEF_02972	8.36e-72	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose Cellobiose specific IIA subunit
HKANDMEF_02973	1.82e-140	yokL3	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HKANDMEF_02974	1.84e-110	-	-	-	F	-	-	-	NUDIX domain
HKANDMEF_02975	1.35e-119	-	-	-	S	-	-	-	AAA domain
HKANDMEF_02976	3.32e-148	ycaC	-	-	Q	-	-	-	Isochorismatase family
HKANDMEF_02977	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HKANDMEF_02978	1.38e-274	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
HKANDMEF_02979	2.11e-220	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
HKANDMEF_02980	1.08e-84	manO	-	-	S	-	-	-	Domain of unknown function (DUF956)
HKANDMEF_02981	1.73e-216	manN	-	-	G	ko:K02796,ko:K02815	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
HKANDMEF_02982	1.57e-171	manM	-	-	G	ko:K02746,ko:K02795,ko:K02814	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
HKANDMEF_02983	1.44e-230	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HKANDMEF_02984	9.77e-279	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HKANDMEF_02985	1.31e-245	-	-	-	K	ko:K20373	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix XRE-family like proteins
HKANDMEF_02986	8.33e-193	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HKANDMEF_02987	6.17e-204	ywdE	-	-	K	ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix XRE-family like proteins
HKANDMEF_02989	0.0	XK27_05795	-	-	P	ko:K17073,ko:K17074	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HKANDMEF_02990	6.58e-173	glnQ	-	-	E	ko:K17076	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HKANDMEF_02991	4.51e-41	-	-	-	-	-	-	-	-
HKANDMEF_02992	2.97e-305	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HKANDMEF_02993	1.33e-166	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
HKANDMEF_02994	2.15e-21	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
HKANDMEF_02995	1.4e-69	-	-	-	-	-	-	-	-
HKANDMEF_02996	6.11e-106	ydbS	-	-	S	ko:K09167	-	ko00000	Bacterial PH domain
HKANDMEF_02997	0.0	ydbT	-	-	S	ko:K08981	-	ko00000	Bacterial PH domain
HKANDMEF_02998	7.76e-186	-	-	-	S	-	-	-	AAA ATPase domain
HKANDMEF_02999	5.81e-217	-	-	-	G	-	-	-	Phosphotransferase enzyme family
HKANDMEF_03000	1.09e-170	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HKANDMEF_03001	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HKANDMEF_03002	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HKANDMEF_03003	9.37e-129	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HKANDMEF_03004	7.75e-138	-	-	-	S	ko:K06384	-	ko00000	Stage II sporulation protein M
HKANDMEF_03005	1.51e-90	moxR	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
HKANDMEF_03006	6.74e-112	moxR	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
HKANDMEF_03007	5.5e-238	-	-	-	S	-	-	-	Protein of unknown function DUF58
HKANDMEF_03008	1.77e-51	yebA	-	-	E	-	-	-	Transglutaminase/protease-like homologues
HKANDMEF_03009	0.0	yebA	-	-	E	-	-	-	Transglutaminase/protease-like homologues
HKANDMEF_03010	2.11e-273	-	-	-	M	-	-	-	Glycosyl transferases group 1
HKANDMEF_03011	1.34e-126	thgA3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HKANDMEF_03012	9.44e-190	-	3.1.3.102, 3.1.3.104, 3.1.3.23	-	G	ko:K07757,ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
HKANDMEF_03013	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Fumarase C C-terminus
HKANDMEF_03014	8.59e-149	-	-	-	S	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
HKANDMEF_03015	2.11e-61	yjdF3	-	-	S	-	-	-	Protein of unknown function (DUF2992)
HKANDMEF_03016	1.09e-273	mae	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme, NAD binding domain
HKANDMEF_03017	5.39e-292	malP	-	-	C	ko:K11616	ko02020,map02020	ko00000,ko00001	2-hydroxycarboxylate transporter family
HKANDMEF_03018	0.0	dpiB	2.7.13.3	-	T	ko:K02476,ko:K11614	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Single cache domain 3
HKANDMEF_03019	1.62e-159	malR	-	-	KT	ko:K02475,ko:K11615	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	cheY-homologous receiver domain
HKANDMEF_03020	6.61e-196	-	-	-	I	-	-	-	NAD binding domain of 6-phosphogluconate dehydrogenase
HKANDMEF_03021	5.33e-124	M1-431	-	-	S	-	-	-	Protein of unknown function (DUF1706)
HKANDMEF_03022	1.58e-86	-	-	-	-	-	-	-	-
HKANDMEF_03023	2.35e-286	yagE	-	-	E	-	-	-	Amino acid permease
HKANDMEF_03024	7.05e-219	-	-	-	O	-	-	-	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HKANDMEF_03025	3.09e-212	sip	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HKANDMEF_03026	2.54e-55	-	-	-	L	-	-	-	DNA integration
HKANDMEF_03027	6.37e-144	-	-	-	K	ko:K07729	-	ko00000,ko03000	sequence-specific DNA binding
HKANDMEF_03029	7.41e-45	-	-	-	-	-	-	-	-
HKANDMEF_03030	5.45e-26	-	-	-	-	-	-	-	-
HKANDMEF_03031	3.31e-39	-	-	-	-	-	-	-	-
HKANDMEF_03033	7.72e-35	-	-	-	-	-	-	-	-
HKANDMEF_03034	1.64e-205	-	-	-	L	-	-	-	Bifunctional DNA primase/polymerase, N-terminal
HKANDMEF_03035	0.0	-	-	-	S	ko:K06919	-	ko00000	Phage plasmid primase, P4
HKANDMEF_03036	9.69e-72	-	-	-	S	-	-	-	Phage head-tail joining protein
HKANDMEF_03038	1.06e-28	-	-	-	L	-	-	-	HNH endonuclease
HKANDMEF_03039	9.78e-107	terS	-	-	L	-	-	-	Phage terminase, small subunit
HKANDMEF_03040	0.0	terL	-	-	S	-	-	-	overlaps another CDS with the same product name
HKANDMEF_03041	3e-29	-	-	-	-	-	-	-	-
HKANDMEF_03042	5.1e-284	-	-	-	S	-	-	-	Phage portal protein
HKANDMEF_03043	0.0	-	-	-	S	ko:K06904	-	ko00000	Phage capsid family
HKANDMEF_03044	8.23e-62	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HKANDMEF_03045	2.3e-23	-	-	-	-	-	-	-	-
HKANDMEF_03046	1.4e-35	ytgB	-	-	S	-	-	-	Transglycosylase associated protein
HKANDMEF_03048	3.23e-218	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HKANDMEF_03049	2.32e-233	-	-	-	D	ko:K06889	-	ko00000	Alpha beta
HKANDMEF_03050	5.29e-239	lipA	-	-	I	-	-	-	Carboxylesterase family
HKANDMEF_03051	1.68e-275	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
HKANDMEF_03052	9.2e-101	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKANDMEF_03053	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	Mga helix-turn-helix domain
HKANDMEF_03054	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HKANDMEF_03055	2.05e-168	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HKANDMEF_03056	3.86e-192	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HKANDMEF_03057	8.43e-59	-	-	-	-	-	-	-	-
HKANDMEF_03058	6.72e-19	-	-	-	-	-	-	-	-
HKANDMEF_03059	3.71e-239	hlyD3	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HKANDMEF_03060	7.13e-161	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HKANDMEF_03061	2.53e-265	yknZ	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HKANDMEF_03062	1.77e-220	-	-	-	M	-	-	-	Leucine rich repeats (6 copies)
HKANDMEF_03063	0.0	-	-	-	M	-	-	-	Leucine rich repeats (6 copies)
HKANDMEF_03064	3.28e-257	ypjH	-	-	C	ko:K08317	-	ko00000,ko01000	dehydrogenase
HKANDMEF_03065	5.35e-289	amd	-	-	E	-	-	-	Peptidase family M20/M25/M40
HKANDMEF_03066	1.48e-104	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HKANDMEF_03067	3.8e-175	labL	-	-	S	-	-	-	Putative threonine/serine exporter
HKANDMEF_03069	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HKANDMEF_03070	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HKANDMEF_03072	1.73e-171	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
HKANDMEF_03073	4.53e-179	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HKANDMEF_03074	2.99e-77	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HKANDMEF_03075	3.26e-23	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
HKANDMEF_03076	2.09e-101	repA	-	-	S	-	-	-	Replication initiator protein A
HKANDMEF_03085	2.14e-163	tnp1216	-	-	L	ko:K07498	-	ko00000	DDE domain
HKANDMEF_03086	2.74e-81	-	-	-	L	-	-	-	Protein of unknown function (DUF3991)
HKANDMEF_03087	4e-112	-	-	-	U	-	-	-	Relaxase/Mobilisation nuclease domain
HKANDMEF_03088	1.03e-08	-	-	-	S	-	-	-	Bacterial mobilisation protein (MobC)
HKANDMEF_03091	1.21e-74	-	-	-	L	-	-	-	IrrE N-terminal-like domain
HKANDMEF_03095	8.57e-43	p40	-	-	D	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	CHAP domain
HKANDMEF_03096	6.91e-314	-	-	-	U	-	-	-	AAA-like domain
HKANDMEF_03097	2.54e-21	-	-	-	U	-	-	-	PrgI family protein
HKANDMEF_03098	1.47e-33	-	-	-	-	-	-	-	-
HKANDMEF_03099	1.74e-21	-	-	-	-	-	-	-	-
HKANDMEF_03100	1.3e-154	-	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	TraM recognition site of TraD and TraG
HKANDMEF_03101	6.87e-11	-	-	-	S	-	-	-	Protein of unknown function (DUF3801)
HKANDMEF_03102	1.44e-61	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
HKANDMEF_03107	2.14e-163	tnp1216	-	-	L	ko:K07498	-	ko00000	DDE domain
HKANDMEF_03108	5.34e-162	larB	-	-	S	ko:K06898	-	ko00000	AIR carboxylase
HKANDMEF_03109	6.2e-175	larC	4.99.1.12	-	S	ko:K09121	-	ko00000,ko01000	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
HKANDMEF_03110	1.19e-170	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HKANDMEF_03111	3.03e-192	larE	-	-	S	ko:K06864	-	ko00000	NAD synthase
HKANDMEF_03112	2.14e-163	tnp1216	-	-	L	ko:K07498	-	ko00000	DDE domain
HKANDMEF_03113	2.33e-200	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
HKANDMEF_03115	1.56e-103	-	-	-	L	-	-	-	Transposase DDE domain
HKANDMEF_03116	2.15e-77	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
HKANDMEF_03117	6.22e-102	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
HKANDMEF_03118	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
HKANDMEF_03119	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
HKANDMEF_03120	6.02e-217	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HKANDMEF_03121	2.93e-279	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HKANDMEF_03122	2.99e-122	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Bacterial transferase hexapeptide (six repeats)
HKANDMEF_03123	3.06e-77	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
HKANDMEF_03124	8.05e-106	-	-	-	L	-	-	-	Transposase DDE domain
HKANDMEF_03125	2.65e-67	lacF	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
HKANDMEF_03126	0.0	lacG	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HKANDMEF_03127	0.0	lacE	2.7.1.207	-	G	ko:K02787,ko:K02788	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase system, EIIC
HKANDMEF_03128	2.08e-207	lacT	-	-	K	ko:K02531	-	ko00000,ko03000	PRD domain
HKANDMEF_03129	3.82e-65	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HKANDMEF_03130	3.15e-103	-	-	-	L	-	-	-	Transposase DDE domain
HKANDMEF_03131	1.51e-77	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
HKANDMEF_03132	3.83e-61	-	-	-	L	-	-	-	BRCA1 C Terminus (BRCT) domain
HKANDMEF_03133	1.14e-148	pinR1	-	-	L	-	-	-	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
HKANDMEF_03135	2.62e-49	-	-	-	L	-	-	-	Transposase DDE domain
HKANDMEF_03136	8.52e-84	is18	-	-	L	-	-	-	Integrase core domain
HKANDMEF_03137	4.83e-50	-	-	-	L	ko:K07483	-	ko00000	Transposase and inactivated derivatives
HKANDMEF_03138	0.0	-	-	-	M	-	-	-	Cna protein B-type domain
HKANDMEF_03140	5.71e-58	-	-	-	L	ko:K07483	-	ko00000	Homeodomain-like domain
HKANDMEF_03141	2.08e-177	-	-	-	L	-	-	-	COG2801 Transposase and inactivated derivatives
HKANDMEF_03143	2.63e-27	-	-	-	-	-	-	-	-
HKANDMEF_03145	2.08e-214	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
HKANDMEF_03146	9.99e-25	-	-	-	-	-	-	-	-
HKANDMEF_03148	5.81e-130	-	-	-	D	-	-	-	AAA domain