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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
APPACOFM_00001	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
APPACOFM_00002	5.67e-177	-	1.5.1.38, 1.5.1.39	-	C	ko:K19285,ko:K19286	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	Nitroreductase family
APPACOFM_00003	0.0	nrd	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen
APPACOFM_00004	0.0	malQ	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 9.26
APPACOFM_00005	6.77e-247	-	-	-	G	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_00006	3.61e-244	-	-	-	M	-	-	-	Glycosyl transferases group 1
APPACOFM_00007	9.61e-84	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
APPACOFM_00008	6.68e-125	mgsA	4.2.3.3	-	G	ko:K01734	ko00640,ko01120,map00640,map01120	ko00000,ko00001,ko01000	methylglyoxal synthase
APPACOFM_00009	3.15e-244	-	-	-	S	ko:K07011	-	ko00000	Glycosyl transferase family group 2
APPACOFM_00010	6.88e-210	waaM	2.3.1.241	-	M	ko:K02517	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Lipid A biosynthesis (KDO)2-(Lauroyl)-lipid IVA acyltransferase
APPACOFM_00011	0.0	yqeV	2.8.4.5	-	J	ko:K18707	-	ko00000,ko01000,ko03016	Psort location Cytoplasmic, score 8.96
APPACOFM_00012	0.0	-	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	Psort location CytoplasmicMembrane, score 9.82
APPACOFM_00013	3.99e-20	-	-	-	S	-	-	-	COG NOG38865 non supervised orthologous group
APPACOFM_00014	2.73e-209	-	-	-	M	-	-	-	COG COG1082 Sugar phosphate isomerases epimerases
APPACOFM_00015	1.46e-141	-	-	-	G	-	-	-	COG NOG16664 non supervised orthologous group
APPACOFM_00016	2.23e-65	-	-	-	G	-	-	-	COG NOG16664 non supervised orthologous group
APPACOFM_00017	0.0	-	-	-	S	-	-	-	Tat pathway signal sequence domain protein
APPACOFM_00018	1.98e-284	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_00019	0.0	-	-	-	G	-	-	-	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
APPACOFM_00020	1.79e-91	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
APPACOFM_00021	3.78e-57	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
APPACOFM_00022	8.84e-74	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
APPACOFM_00023	3.91e-100	ohrR	-	-	K	-	-	-	Transcriptional regulator, MarR family
APPACOFM_00024	3.98e-29	-	-	-	-	-	-	-	-
APPACOFM_00025	2.14e-166	rprY	-	-	K	-	-	-	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
APPACOFM_00026	2.48e-71	rprX	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	two-component regulatory system, sensor kinase protein
APPACOFM_00027	2.24e-251	rprX	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	two-component regulatory system, sensor kinase protein
APPACOFM_00028	0.0	fusA2	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Psort location Cytoplasmic, score 9.26
APPACOFM_00029	1.4e-286	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
APPACOFM_00030	2.28e-120	-	-	-	K	ko:K03088	-	ko00000,ko03021	RNA polymerase sigma-70 factor
APPACOFM_00031	1.09e-95	-	-	-	-	-	-	-	-
APPACOFM_00032	8.12e-204	-	-	-	PT	-	-	-	Domain of unknown function (DUF4974)
APPACOFM_00033	2.4e-220	-	-	-	P	-	-	-	TonB-dependent receptor
APPACOFM_00034	3.92e-162	-	-	-	P	-	-	-	TonB-dependent receptor
APPACOFM_00035	1.02e-161	-	-	-	P	-	-	-	TonB-dependent receptor
APPACOFM_00036	2.68e-253	-	-	-	S	-	-	-	COG NOG27441 non supervised orthologous group
APPACOFM_00037	4.15e-160	-	-	-	P	-	-	-	ATPases associated with a variety of cellular activities
APPACOFM_00038	3.54e-66	-	-	-	-	-	-	-	-
APPACOFM_00039	6.86e-60	-	-	-	S	-	-	-	COG NOG18433 non supervised orthologous group
APPACOFM_00040	1.65e-141	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
APPACOFM_00041	7.15e-75	-	-	-	S	-	-	-	COG NOG30654 non supervised orthologous group
APPACOFM_00042	5.84e-252	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_00043	1.33e-159	-	-	-	S	ko:K07025	-	ko00000	Psort location Cytoplasmic, score 8.96
APPACOFM_00044	2.69e-181	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
APPACOFM_00045	6.04e-156	-	-	-	S	ko:K09702	-	ko00000	Protein of unknown function (DUF1349)
APPACOFM_00046	6.29e-250	-	-	-	S	-	-	-	COG NOG15865 non supervised orthologous group
APPACOFM_00047	2.38e-293	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
APPACOFM_00048	7.65e-136	-	-	-	T	-	-	-	COG COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
APPACOFM_00049	1.33e-167	-	-	-	S	-	-	-	Enoyl-(Acyl carrier protein) reductase
APPACOFM_00050	3.2e-249	-	-	-	M	-	-	-	Peptidase, M28 family
APPACOFM_00051	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
APPACOFM_00052	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
APPACOFM_00053	0.0	-	-	-	K	-	-	-	GxGYxY sequence motif in domain of unknown function N-terminal
APPACOFM_00054	5.45e-231	-	-	-	M	-	-	-	F5/8 type C domain
APPACOFM_00055	0.0	-	-	-	F	ko:K21572	-	ko00000,ko02000	SusD family
APPACOFM_00056	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_00057	9.35e-228	-	-	-	PT	-	-	-	Domain of unknown function (DUF4974)
APPACOFM_00058	1.59e-130	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
APPACOFM_00059	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 92
APPACOFM_00060	0.0	-	-	-	S	-	-	-	GxGYxY sequence motif in domain of unknown function N-terminal
APPACOFM_00061	0.0	-	-	-	E	ko:K21572	-	ko00000,ko02000	SusD family
APPACOFM_00062	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_00063	4.41e-238	-	-	-	S	-	-	-	Concanavalin A-like lectin/glucanases superfamily
APPACOFM_00064	0.0	-	-	-	T	-	-	-	COG NOG26059 non supervised orthologous group
APPACOFM_00065	1.23e-86	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_00066	1.23e-183	znuB	-	-	P	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
APPACOFM_00067	5.09e-93	yjeE	-	-	S	ko:K06925	-	ko00000,ko03016	Psort location Cytoplasmic, score
APPACOFM_00068	5.6e-45	-	-	-	S	-	-	-	COG NOG34862 non supervised orthologous group
APPACOFM_00069	1.04e-64	-	-	-	S	ko:K07075	-	ko00000	Nucleotidyltransferase domain
APPACOFM_00070	2.52e-85	-	-	-	S	-	-	-	Protein of unknown function DUF86
APPACOFM_00071	1.39e-312	-	-	-	S	-	-	-	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
APPACOFM_00072	3.35e-220	-	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
APPACOFM_00073	2.46e-309	-	-	-	S	-	-	-	COG NOG26634 non supervised orthologous group
APPACOFM_00074	4.2e-145	-	-	-	S	-	-	-	Domain of unknown function (DUF4129)
APPACOFM_00075	1.07e-193	-	-	-	-	-	-	-	-
APPACOFM_00076	1.36e-230	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_00078	0.0	-	-	-	S	-	-	-	Peptidase C10 family
APPACOFM_00080	0.0	-	-	-	S	-	-	-	Peptidase C10 family
APPACOFM_00081	6.21e-303	-	-	-	S	-	-	-	Peptidase C10 family
APPACOFM_00083	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
APPACOFM_00084	2.99e-161	-	-	-	S	-	-	-	serine threonine protein kinase
APPACOFM_00085	9.37e-127	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_00086	6.82e-72	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_00087	1.17e-71	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
APPACOFM_00088	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III alpha subunit
APPACOFM_00089	2.41e-117	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
APPACOFM_00090	3.96e-163	pssA	2.7.8.8	-	I	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
APPACOFM_00091	1.47e-56	-	-	-	S	-	-	-	Domain of unknown function (DUF4834)
APPACOFM_00092	7.61e-102	tadA	3.5.4.33	-	FJ	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
APPACOFM_00093	6.13e-48	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_00094	4.42e-84	-	-	-	L	ko:K07460	-	ko00000	Belongs to the UPF0102 family
APPACOFM_00095	2.8e-81	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_00096	3.18e-177	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	biotin acetyl-CoA-carboxylase ligase
APPACOFM_00097	0.0	-	-	-	M	-	-	-	COG0793 Periplasmic protease
APPACOFM_00098	1.95e-150	-	-	-	S	-	-	-	COG NOG28155 non supervised orthologous group
APPACOFM_00099	1.61e-308	dinF	-	-	V	ko:K03327	-	ko00000,ko02000	MATE efflux family protein
APPACOFM_00100	3.79e-08	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
APPACOFM_00101	2.16e-113	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
APPACOFM_00103	2.81e-258	-	-	-	D	-	-	-	Tetratricopeptide repeat
APPACOFM_00105	0.0	-	-	-	P	-	-	-	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
APPACOFM_00106	1.39e-68	-	-	-	P	-	-	-	RyR domain
APPACOFM_00107	1.74e-184	-	-	-	EG	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_00108	1.37e-123	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
APPACOFM_00109	4.65e-229	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
APPACOFM_00110	2.1e-248	-	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
APPACOFM_00111	0.0	bepE_4	-	-	V	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
APPACOFM_00112	0.0	bepE_4	-	-	V	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
APPACOFM_00113	1.06e-313	tolC	-	-	MU	-	-	-	Psort location OuterMembrane, score
APPACOFM_00114	2.88e-273	pelA	3.1.1.11	-	G	ko:K01051	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	pectate lyase
APPACOFM_00115	4.55e-288	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_00116	0.0	fumB	4.2.1.2	-	C	ko:K01676	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible hydration of fumarate to (S)- malate
APPACOFM_00117	2.29e-261	-	-	-	JM	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_00118	2.94e-201	-	-	-	JM	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_00119	2.46e-30	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
APPACOFM_00120	2.02e-232	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
APPACOFM_00121	0.0	-	-	-	H	-	-	-	Susd and RagB outer membrane lipoprotein
APPACOFM_00122	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_00123	1.68e-288	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_00124	1.45e-280	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
APPACOFM_00125	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_00126	4.16e-310	-	-	-	S	ko:K21572	-	ko00000,ko02000	SusD family
APPACOFM_00127	4.82e-147	-	-	-	U	ko:K05595	-	ko00000,ko02000	UPF0056 membrane protein
APPACOFM_00128	1.24e-168	yjjG	-	-	S	ko:K07025	-	ko00000	HAD hydrolase, TIGR02254 family
APPACOFM_00129	1.04e-171	-	-	-	S	-	-	-	Transposase
APPACOFM_00130	1.5e-157	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
APPACOFM_00131	8.44e-93	-	-	-	S	-	-	-	COG NOG23390 non supervised orthologous group
APPACOFM_00132	2.2e-120	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
APPACOFM_00133	2.02e-250	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_00135	2.4e-177	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
APPACOFM_00136	3.62e-65	-	-	-	S	-	-	-	MerR HTH family regulatory protein
APPACOFM_00137	6.02e-64	-	-	-	S	-	-	-	Domain of unknown function, B. Theta Gene description (DUF3876)
APPACOFM_00139	6.47e-205	-	-	-	K	-	-	-	Helix-turn-helix domain
APPACOFM_00140	2.29e-97	-	-	-	S	-	-	-	Variant SH3 domain
APPACOFM_00141	1.13e-58	-	-	-	S	ko:K07343	-	ko00000	TfoX C-terminal domain
APPACOFM_00142	5.83e-223	-	-	-	E	-	-	-	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
APPACOFM_00143	1.45e-189	-	-	-	K	-	-	-	Helix-turn-helix domain
APPACOFM_00144	5.21e-88	-	-	-	-	-	-	-	-
APPACOFM_00145	5.73e-156	-	-	-	S	-	-	-	CAAX protease self-immunity
APPACOFM_00146	1.63e-159	-	-	-	C	-	-	-	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
APPACOFM_00147	6.08e-33	-	-	-	S	-	-	-	DJ-1/PfpI family
APPACOFM_00148	5.17e-83	-	-	-	L	ko:K07497	-	ko00000	transposase activity
APPACOFM_00149	7.67e-79	-	-	-	L	ko:K07484	-	ko00000	IS66 Orf2 like protein
APPACOFM_00150	0.0	-	-	-	L	-	-	-	Transposase C of IS166 homeodomain
APPACOFM_00152	0.0	-	-	-	-	-	-	-	-
APPACOFM_00153	0.0	-	-	-	S	-	-	-	DNA-sulfur modification-associated
APPACOFM_00154	4.12e-21	-	-	-	S	-	-	-	DNA-sulfur modification-associated
APPACOFM_00155	3.25e-281	-	2.1.1.72	-	H	ko:K07318	-	ko00000,ko01000,ko02048	COG3392 Adenine-specific DNA methylase
APPACOFM_00156	2.92e-172	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_00157	5.62e-30	-	-	-	-	-	-	-	-
APPACOFM_00159	7.8e-198	-	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Formamidopyrimidine-DNA glycosylase H2TH domain
APPACOFM_00160	7.25e-88	-	-	-	K	-	-	-	Helix-turn-helix domain
APPACOFM_00161	1.82e-80	-	-	-	K	-	-	-	Helix-turn-helix domain
APPACOFM_00162	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_00163	0.0	-	-	-	K	ko:K21572	-	ko00000,ko02000	SusD family
APPACOFM_00164	4.21e-230	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_00165	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_00166	0.0	-	-	-	E	ko:K21572	-	ko00000,ko02000	Pfam:SusD
APPACOFM_00167	8.61e-132	-	-	-	T	-	-	-	Cyclic nucleotide-binding domain protein
APPACOFM_00168	1.22e-213	-	-	-	I	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_00169	1.42e-47	-	-	-	S	-	-	-	Winged helix-turn-helix domain (DUF2582)
APPACOFM_00170	1.2e-151	-	-	-	O	-	-	-	Heat shock protein
APPACOFM_00171	3.69e-111	-	-	-	K	-	-	-	acetyltransferase
APPACOFM_00172	9.25e-134	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
APPACOFM_00173	1.62e-37	-	-	-	K	ko:K13652	-	ko00000,ko03000	methylphosphotriester-DNA alkyltransferase (AraC XylS family)
APPACOFM_00174	5.15e-57	-	-	-	K	ko:K13652	-	ko00000,ko03000	methylphosphotriester-DNA alkyltransferase (AraC XylS family)
APPACOFM_00175	0.0	-	-	-	E	-	-	-	Domain of Unknown Function with PDB structure (DUF3858)
APPACOFM_00176	0.0	-	-	-	E	-	-	-	Domain of Unknown Function with PDB structure (DUF3857)
APPACOFM_00177	8.68e-127	-	-	-	K	-	-	-	Protein of unknown function (DUF3788)
APPACOFM_00178	3.04e-313	mepA_6	-	-	V	-	-	-	MATE efflux family protein
APPACOFM_00179	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 28 family
APPACOFM_00180	1.06e-176	-	-	-	S	-	-	-	Alpha/beta hydrolase family
APPACOFM_00181	1.81e-166	-	-	-	S	-	-	-	KR domain
APPACOFM_00182	5.28e-127	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
APPACOFM_00183	1.63e-145	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
APPACOFM_00184	1.93e-144	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
APPACOFM_00185	1.36e-116	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
APPACOFM_00186	5.74e-154	vat_2	-	-	S	ko:K18234	-	ko00000,ko01000,ko01504	Bacterial transferase hexapeptide repeat protein
APPACOFM_00187	1.72e-209	-	2.1.1.266	-	S	ko:K07115	-	ko00000,ko01000,ko03009	COG COG2961 Protein involved in catabolism of external DNA
APPACOFM_00188	2.81e-106	lrp	-	-	K	ko:K03719,ko:K05800	-	ko00000,ko03000,ko03036	Transcriptional regulator, AsnC family
APPACOFM_00189	8.28e-310	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
APPACOFM_00190	7.33e-50	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_00191	2.82e-206	mscS	-	-	M	ko:K03442	-	ko00000,ko02000	Small-conductance mechanosensitive channel
APPACOFM_00192	0.0	-	-	-	P	ko:K02014	-	ko00000,ko02000	COG COG1629 Outer membrane receptor proteins, mostly Fe transport
APPACOFM_00193	0.0	-	-	-	T	-	-	-	Y_Y_Y domain
APPACOFM_00194	0.0	-	-	-	S	-	-	-	NHL repeat
APPACOFM_00195	0.0	-	-	-	P	-	-	-	TonB dependent receptor
APPACOFM_00196	0.0	-	-	-	P	ko:K21572	-	ko00000,ko02000	Psort location OuterMembrane, score
APPACOFM_00197	2.96e-210	-	-	-	S	-	-	-	Domain of unknown function (DUF4361)
APPACOFM_00198	9.66e-138	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
APPACOFM_00199	1.92e-147	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Thiamine diphosphokinase
APPACOFM_00200	7.36e-139	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	COG COG2818 3-methyladenine DNA glycosylase
APPACOFM_00201	1.2e-84	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
APPACOFM_00202	1.08e-208	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
APPACOFM_00203	1.65e-172	-	5.4.2.12	-	G	ko:K15635	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	homoserine kinase
APPACOFM_00204	7.63e-104	-	5.4.2.12	-	G	ko:K15635	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	homoserine kinase
APPACOFM_00205	0.0	thrA	1.1.1.3, 2.7.2.4	-	E	ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
APPACOFM_00206	1.92e-241	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase, type I
APPACOFM_00207	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
APPACOFM_00208	0.0	-	-	-	S	ko:K07137	-	ko00000	FAD-dependent
APPACOFM_00209	1.07e-136	-	-	-	K	-	-	-	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
APPACOFM_00210	0.0	-	-	-	P	-	-	-	Outer membrane receptor
APPACOFM_00211	3.21e-178	-	-	-	K	-	-	-	methylphosphotriester-DNA alkyltransferase and transcriptional regulator (AraC XylS family)
APPACOFM_00212	1.77e-177	-	-	-	L	-	-	-	Integrase core domain
APPACOFM_00213	2.41e-84	-	-	-	L	ko:K07483	-	ko00000	COG2963 Transposase and inactivated derivatives
APPACOFM_00214	8.94e-120	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_00215	1.17e-246	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
APPACOFM_00216	0.0	prtQ	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Psort location Cytoplasmic, score 8.96
APPACOFM_00217	1.28e-228	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
APPACOFM_00218	1.87e-35	-	-	-	C	-	-	-	4Fe-4S binding domain
APPACOFM_00219	7.27e-286	aspC	2.6.1.1	-	E	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	COG0436 Aspartate tyrosine aromatic aminotransferase
APPACOFM_00220	1.81e-294	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
APPACOFM_00221	0.0	-	-	-	S	ko:K07091	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Permease, YjgP YjgQ family
APPACOFM_00222	5.89e-90	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_00224	1.53e-309	-	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Psort location Cytoplasmic, score
APPACOFM_00225	4.12e-249	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
APPACOFM_00226	4.38e-63	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
APPACOFM_00227	4.73e-265	kdpD	2.7.13.3	-	T	ko:K07646	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Psort location Cytoplasmic, score 8.96
APPACOFM_00228	1.34e-181	-	-	-	S	-	-	-	COG NOG26951 non supervised orthologous group
APPACOFM_00229	5.81e-131	kdpC	3.6.3.12	-	P	ko:K01548	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
APPACOFM_00230	3.75e-84	kdpB	3.6.3.12	-	P	ko:K01547	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
APPACOFM_00231	0.0	kdpB	3.6.3.12	-	P	ko:K01547	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
APPACOFM_00232	0.0	kdpA	3.6.3.12	-	P	ko:K01546	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
APPACOFM_00236	2.37e-220	-	-	-	L	-	-	-	Integrase core domain
APPACOFM_00237	1.81e-78	-	-	-	-	-	-	-	-
APPACOFM_00239	1.33e-295	-	2.7.1.1	-	G	ko:K00844	ko00010,ko00051,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04910,ko04930,ko04973,ko05230,map00010,map00051,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200,map04066,map04910,map04930,map04973,map05230	ko00000,ko00001,ko00002,ko01000,ko04131	Hexokinase
APPACOFM_00240	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
APPACOFM_00241	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 2 family
APPACOFM_00242	0.0	-	-	-	T	ko:K02481	-	ko00000,ko02022	acetoacetate metabolism regulatory protein AtoC
APPACOFM_00243	0.0	cdr	-	-	P	-	-	-	Belongs to the sulfur carrier protein TusA family
APPACOFM_00244	1.42e-76	-	-	-	K	-	-	-	Transcriptional regulator, MarR
APPACOFM_00245	4.99e-138	-	-	-	S	-	-	-	PS-10 peptidase S37
APPACOFM_00246	8e-165	-	-	-	S	-	-	-	PS-10 peptidase S37
APPACOFM_00247	3.3e-145	-	-	-	S	-	-	-	COG NOG26965 non supervised orthologous group
APPACOFM_00248	3.46e-155	-	-	-	M	-	-	-	COG NOG27406 non supervised orthologous group
APPACOFM_00249	0.0	nagA	-	-	G	-	-	-	b-glycosidase, glycoside hydrolase family 3 protein
APPACOFM_00250	1.13e-217	-	3.1.3.5, 3.6.1.45	-	F	ko:K01081,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Ser Thr phosphatase family protein
APPACOFM_00251	5.97e-188	ushA	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	5'-nucleotidase, C-terminal domain
APPACOFM_00252	3.46e-265	-	-	-	M	-	-	-	COG2885 Outer membrane protein and related peptidoglycan-associated
APPACOFM_00253	0.0	-	-	-	N	-	-	-	bacterial-type flagellum assembly
APPACOFM_00254	1.03e-92	-	-	-	L	-	-	-	Phage integrase family
APPACOFM_00255	4.64e-295	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
APPACOFM_00256	5.38e-291	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
APPACOFM_00257	1.04e-64	-	-	-	L	-	-	-	Helix-turn-helix domain
APPACOFM_00259	1.16e-202	-	-	-	S	-	-	-	Domain of unknown function (DUF4377)
APPACOFM_00260	0.0	-	3.4.22.10	-	S	ko:K01364	ko01503,ko02024,map01503,map02024	ko00000,ko00001,ko01000,ko01002	Peptidase_C39 like family
APPACOFM_00261	4.27e-89	-	-	-	-	-	-	-	-
APPACOFM_00262	6.23e-56	-	-	-	-	-	-	-	-
APPACOFM_00263	2.51e-114	-	-	-	L	-	-	-	COG COG3344 Retron-type reverse transcriptase
APPACOFM_00264	1.43e-111	-	-	-	L	-	-	-	COG COG3344 Retron-type reverse transcriptase
APPACOFM_00265	8.89e-292	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase superfamily domain
APPACOFM_00266	1.03e-259	-	-	-	Q	-	-	-	FAD dependent oxidoreductase
APPACOFM_00267	3.01e-128	-	-	-	Q	-	-	-	FAD dependent oxidoreductase
APPACOFM_00268	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycosyl hydrolase family 20, catalytic domain protein
APPACOFM_00269	0.0	-	-	-	F	ko:K21572	-	ko00000,ko02000	SusD family
APPACOFM_00270	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_00271	3.03e-231	-	-	-	PT	-	-	-	Sigma factor regulatory protein, FecR PupR family
APPACOFM_00272	8.25e-131	-	-	-	K	ko:K03088	-	ko00000,ko03021	RNA polymerase sigma-70 factor
APPACOFM_00274	6.59e-226	-	-	-	S	-	-	-	Putative amidoligase enzyme
APPACOFM_00276	1.03e-87	-	-	-	S	-	-	-	Protein of unknown function (DUF3408)
APPACOFM_00277	3.94e-19	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_00278	1.39e-34	-	-	-	K	-	-	-	Helix-turn-helix domain
APPACOFM_00279	6.02e-64	-	-	-	S	-	-	-	DNA binding domain, excisionase family
APPACOFM_00280	4.47e-39	-	-	-	L	-	-	-	Phage integrase family
APPACOFM_00282	8.58e-28	-	-	-	S	-	-	-	COG NOG16623 non supervised orthologous group
APPACOFM_00283	0.0	-	-	-	-	-	-	-	-
APPACOFM_00284	0.0	ccsA	-	-	O	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_00285	4.54e-287	-	-	-	J	-	-	-	endoribonuclease L-PSP
APPACOFM_00286	7.46e-177	-	-	-	-	-	-	-	-
APPACOFM_00287	9.18e-292	-	-	-	P	-	-	-	Psort location OuterMembrane, score
APPACOFM_00288	0.0	-	-	-	C	-	-	-	Di-haem oxidoreductase, putative peroxidase
APPACOFM_00289	2.19e-272	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
APPACOFM_00290	0.0	-	-	-	S	-	-	-	Psort location OuterMembrane, score
APPACOFM_00291	1.79e-82	-	-	-	-	-	-	-	-
APPACOFM_00292	1.01e-86	-	-	-	K	-	-	-	transcriptional regulator, TetR family
APPACOFM_00293	1.9e-186	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
APPACOFM_00294	4.17e-262	-	-	-	M	-	-	-	COG2885 Outer membrane protein and related peptidoglycan-associated
APPACOFM_00295	0.0	-	-	-	S	-	-	-	Domain of unknown function
APPACOFM_00296	7.16e-231	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
APPACOFM_00297	4e-76	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
APPACOFM_00298	9.98e-134	-	-	-	-	-	-	-	-
APPACOFM_00299	2.05e-109	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70, region 4
APPACOFM_00300	8.85e-131	glk	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 9.26
APPACOFM_00301	9.77e-84	glk	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 9.26
APPACOFM_00302	9.38e-168	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
APPACOFM_00303	1.47e-303	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Efflux ABC transporter, permease protein
APPACOFM_00304	6.62e-297	macB_3	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Efflux ABC transporter, permease protein
APPACOFM_00305	7.55e-245	-	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
APPACOFM_00306	6.05e-307	-	-	-	MU	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	Psort location OuterMembrane, score 10.00
APPACOFM_00307	2.59e-258	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
APPACOFM_00308	4.71e-124	-	-	-	S	-	-	-	COG NOG29882 non supervised orthologous group
APPACOFM_00309	0.0	pbpF	-	-	M	-	-	-	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
APPACOFM_00310	1.46e-153	-	-	-	S	-	-	-	COG NOG36047 non supervised orthologous group
APPACOFM_00311	1.1e-161	-	-	-	J	-	-	-	Domain of unknown function (DUF4476)
APPACOFM_00312	8.23e-65	-	-	-	J	-	-	-	Domain of unknown function (DUF4476)
APPACOFM_00313	2.82e-163	-	-	-	J	-	-	-	Domain of unknown function (DUF4476)
APPACOFM_00314	4.04e-203	yitL	-	-	S	ko:K00243	-	ko00000	Psort location Cytoplasmic, score 8.96
APPACOFM_00315	8.52e-83	-	-	-	L	ko:K07497	-	ko00000	transposase activity
APPACOFM_00316	4.9e-68	-	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 like protein
APPACOFM_00317	0.0	-	-	-	L	-	-	-	Transposase IS66 family
APPACOFM_00319	9.85e-178	-	-	-	-	-	-	-	-
APPACOFM_00320	1.08e-121	-	-	-	KLT	-	-	-	WG containing repeat
APPACOFM_00321	1.14e-224	-	-	-	K	-	-	-	WYL domain
APPACOFM_00322	7.56e-242	mdh	1.1.1.37	-	C	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the LDH MDH superfamily
APPACOFM_00323	2.71e-98	-	-	-	P	ko:K03711	-	ko00000,ko03000	Psort location Cytoplasmic, score 8.96
APPACOFM_00324	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_00325	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 92
APPACOFM_00326	7.33e-152	-	-	-	-	-	-	-	-
APPACOFM_00327	1.81e-78	-	-	-	-	-	-	-	-
APPACOFM_00328	2.37e-220	-	-	-	L	-	-	-	Integrase core domain
APPACOFM_00329	0.0	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
APPACOFM_00330	2.39e-65	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
APPACOFM_00331	1.64e-86	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
APPACOFM_00332	1.68e-149	-	-	-	I	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_00333	0.0	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	COG1508 DNA-directed RNA polymerase specialized sigma subunit sigma54 homolog
APPACOFM_00334	0.0	pepP	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	Psort location Cytoplasmic, score
APPACOFM_00335	0.0	-	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Alpha-L-rhamnosidase N-terminal domain protein
APPACOFM_00336	0.0	-	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	COG NOG04002 non supervised orthologous group
APPACOFM_00337	0.0	-	-	-	Q	-	-	-	COG3458 Acetyl esterase (deacetylase)
APPACOFM_00338	2.27e-98	-	-	-	-	-	-	-	-
APPACOFM_00339	0.0	udk2	2.7.1.48	-	FJ	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Phosphoribulokinase Uridine kinase family
APPACOFM_00340	0.0	-	-	-	P	ko:K03324	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_00341	4.54e-266	-	3.1.3.97	-	S	ko:K07053	-	ko00000,ko01000	Domain of unknown function
APPACOFM_00342	0.0	-	-	-	S	-	-	-	NHL repeat
APPACOFM_00343	0.0	-	-	-	P	-	-	-	TonB dependent receptor
APPACOFM_00344	0.0	-	-	-	M	ko:K21572	-	ko00000,ko02000	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
APPACOFM_00345	9.13e-80	-	-	-	M	ko:K21572	-	ko00000,ko02000	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
APPACOFM_00346	7.91e-216	-	-	-	S	-	-	-	Pfam:DUF5002
APPACOFM_00347	5.51e-142	-	-	-	L	-	-	-	COG NOG29822 non supervised orthologous group
APPACOFM_00349	4.17e-83	-	-	-	-	-	-	-	-
APPACOFM_00350	3.12e-105	-	-	-	L	-	-	-	DNA-binding protein
APPACOFM_00351	8.53e-38	rubR	-	-	C	-	-	-	Psort location Cytoplasmic, score
APPACOFM_00352	4.16e-272	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
APPACOFM_00353	0.0	yoaB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_00354	2.06e-157	yoaB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_00355	2.08e-151	yihX	3.1.3.10, 3.1.3.104	-	S	ko:K07025,ko:K20866,ko:K21063	ko00010,ko00740,ko01100,ko01110,ko01120,map00010,map00740,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.96
APPACOFM_00356	1.36e-226	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	riboflavin biosynthesis protein
APPACOFM_00357	2.65e-177	-	-	-	S	ko:K07052	-	ko00000	CAAX amino terminal protease family
APPACOFM_00358	1.82e-146	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
APPACOFM_00359	2.67e-38	-	-	-	K	ko:K07727	-	ko00000,ko03000	Psort location Cytoplasmic, score 8.96
APPACOFM_00360	1.19e-93	sufE	-	-	S	ko:K02426	-	ko00000	COG2166 SufE protein probably involved in Fe-S center assembly
APPACOFM_00361	2.28e-251	ywaD	-	-	S	-	-	-	glutaminyl-peptide cyclotransferase (glutaminyl cyclase) K00683
APPACOFM_00362	8.61e-221	ykfA	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	proteins, homologs of microcin C7 resistance protein MccF
APPACOFM_00363	5.74e-202	bglA_1	-	-	G	-	-	-	Glycosyl hydrolase family 16
APPACOFM_00364	5.22e-228	-	2.3.1.19, 2.3.1.8	-	C	ko:K00625,ko:K00634	ko00430,ko00620,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00650,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
APPACOFM_00365	4.83e-255	buk	2.7.2.7	-	H	ko:K00929	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	Belongs to the acetokinase family
APPACOFM_00366	0.0	-	-	-	H	-	-	-	COG NOG08812 non supervised orthologous group
APPACOFM_00367	1.59e-94	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
APPACOFM_00368	3.63e-66	-	-	-	-	-	-	-	-
APPACOFM_00369	2.41e-84	-	-	-	L	ko:K07483	-	ko00000	COG2963 Transposase and inactivated derivatives
APPACOFM_00370	1.77e-177	-	-	-	L	-	-	-	Integrase core domain
APPACOFM_00371	0.0	-	-	-	S	-	-	-	COG NOG26858 non supervised orthologous group
APPACOFM_00372	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_00373	4.47e-228	-	-	-	PT	-	-	-	Sigma factor regulatory protein, FecR PupR family
APPACOFM_00374	3.18e-97	-	-	-	K	ko:K03088	-	ko00000,ko03021	RNA polymerase sigma-70 factor
APPACOFM_00375	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
APPACOFM_00376	3.26e-275	-	-	-	O	-	-	-	COG NOG14454 non supervised orthologous group
APPACOFM_00377	5.65e-96	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
APPACOFM_00378	1.33e-87	hinT	-	-	FG	ko:K02503	-	ko00000,ko04147	COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family
APPACOFM_00379	2.73e-210	-	-	-	EG	-	-	-	COG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
APPACOFM_00380	3.19e-282	-	-	-	P	-	-	-	Transporter, major facilitator family protein
APPACOFM_00381	6.74e-117	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
APPACOFM_00383	0.0	gadB	4.1.1.15, 4.1.2.27	-	E	ko:K01580,ko:K01634	ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940	ko00000,ko00001,ko00002,ko01000	Belongs to the group II decarboxylase family
APPACOFM_00384	2.31e-230	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
APPACOFM_00385	2.25e-157	-	-	-	P	ko:K10716	-	ko00000,ko02000	Ion channel
APPACOFM_00386	0.0	gadC	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_00387	7.46e-297	-	-	-	T	-	-	-	Histidine kinase-like ATPases
APPACOFM_00389	8.19e-19	-	-	-	-	-	-	-	-
APPACOFM_00390	8.67e-302	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
APPACOFM_00391	2.21e-42	-	-	-	-	-	-	-	-
APPACOFM_00392	6.51e-35	-	-	-	-	-	-	-	-
APPACOFM_00393	2.55e-268	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_00394	5.59e-218	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_00395	2.48e-52	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_00396	7.04e-118	-	-	-	S	-	-	-	Domain of unknown function (DUF4313)
APPACOFM_00397	2.1e-147	-	-	-	-	-	-	-	-
APPACOFM_00398	1.52e-67	-	-	-	-	-	-	-	-
APPACOFM_00399	6.32e-42	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_00400	1.74e-249	-	-	-	O	-	-	-	DnaJ molecular chaperone homology domain
APPACOFM_00401	9.83e-172	-	-	-	-	-	-	-	-
APPACOFM_00402	1.11e-149	-	-	-	-	-	-	-	-
APPACOFM_00403	1.72e-71	-	-	-	-	-	-	-	-
APPACOFM_00404	2.1e-68	-	-	-	S	-	-	-	Domain of unknown function (DUF4120)
APPACOFM_00405	4.03e-62	-	-	-	-	-	-	-	-
APPACOFM_00406	1.66e-210	-	-	-	S	-	-	-	Domain of unknown function (DUF4121)
APPACOFM_00407	5.5e-192	-	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction enzyme
APPACOFM_00408	1.65e-305	-	-	-	-	-	-	-	-
APPACOFM_00409	4.98e-220	-	-	-	E	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_00410	3.38e-273	-	-	-	-	-	-	-	-
APPACOFM_00411	6.61e-230	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_00412	6.1e-116	-	3.2.1.17	-	S	ko:K01185	-	ko00000,ko01000	lysozyme
APPACOFM_00413	7.52e-109	-	-	-	S	-	-	-	COG NOG28378 non supervised orthologous group
APPACOFM_00414	1.87e-139	-	-	-	S	-	-	-	Conjugative transposon protein TraO
APPACOFM_00415	1.06e-231	-	-	-	U	-	-	-	Conjugative transposon TraN protein
APPACOFM_00416	8.2e-113	traM	-	-	S	-	-	-	Conjugative transposon TraM protein
APPACOFM_00418	3.85e-66	-	-	-	-	-	-	-	-
APPACOFM_00419	5.29e-145	-	-	-	U	-	-	-	Conjugative transposon TraK protein
APPACOFM_00420	6.13e-234	traJ	-	-	S	-	-	-	Conjugative transposon TraJ protein
APPACOFM_00421	9.27e-115	-	-	-	U	-	-	-	COG NOG09946 non supervised orthologous group
APPACOFM_00422	1.37e-83	-	-	-	S	-	-	-	Domain of unknown function, B. Theta Gene description (DUF3876)
APPACOFM_00423	0.0	-	-	-	U	-	-	-	Conjugation system ATPase, TraG family
APPACOFM_00424	1.14e-69	-	-	-	S	-	-	-	Domain of unknown function (DUF4133)
APPACOFM_00425	2.65e-55	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
APPACOFM_00426	0.0	-	-	-	S	-	-	-	Protein of unknown function DUF262
APPACOFM_00427	9.47e-238	-	-	-	S	-	-	-	Protein of unknown function (DUF3696)
APPACOFM_00428	1.21e-215	-	-	-	-	-	-	-	-
APPACOFM_00429	1.39e-156	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_00430	9.93e-99	-	-	-	S	-	-	-	Protein of unknown function (DUF3408)
APPACOFM_00431	3.69e-187	-	-	-	D	-	-	-	COG NOG26689 non supervised orthologous group
APPACOFM_00432	5.6e-67	-	-	-	S	-	-	-	COG NOG37914 non supervised orthologous group
APPACOFM_00433	2.94e-82	-	-	-	U	-	-	-	Relaxase mobilization nuclease domain protein
APPACOFM_00434	8.88e-186	-	-	-	U	-	-	-	Relaxase mobilization nuclease domain protein
APPACOFM_00435	0.0	-	-	-	U	-	-	-	COG COG3505 Type IV secretory pathway, VirD4 components
APPACOFM_00436	2.18e-80	-	-	-	-	-	-	-	-
APPACOFM_00437	2.57e-176	-	-	-	-	-	-	-	-
APPACOFM_00438	2.61e-117	-	-	-	-	-	-	-	-
APPACOFM_00439	1.77e-175	-	-	-	S	-	-	-	Domain of unknown function (DUF1911)
APPACOFM_00440	1.37e-259	-	-	-	-	-	-	-	-
APPACOFM_00441	0.0	-	-	-	S	-	-	-	oxidoreductase activity
APPACOFM_00442	1.49e-219	-	-	-	S	-	-	-	Pkd domain
APPACOFM_00443	7.85e-122	-	-	-	S	-	-	-	Family of unknown function (DUF5469)
APPACOFM_00444	7.74e-67	-	-	-	S	-	-	-	Family of unknown function (DUF5469)
APPACOFM_00445	1.02e-18	-	-	-	S	-	-	-	Family of unknown function (DUF5469)
APPACOFM_00446	4.49e-232	-	-	-	S	-	-	-	Pfam:T6SS_VasB
APPACOFM_00447	7.32e-294	-	-	-	S	-	-	-	type VI secretion protein
APPACOFM_00448	3.13e-201	-	-	-	S	-	-	-	Family of unknown function (DUF5467)
APPACOFM_00449	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_00450	2.06e-107	-	-	-	S	-	-	-	Gene 25-like lysozyme
APPACOFM_00451	4.81e-94	-	-	-	-	-	-	-	-
APPACOFM_00452	4.97e-93	-	-	-	-	-	-	-	-
APPACOFM_00453	2.68e-50	-	-	-	-	-	-	-	-
APPACOFM_00455	1.06e-90	-	-	-	-	-	-	-	-
APPACOFM_00456	5.9e-98	-	-	-	-	-	-	-	-
APPACOFM_00457	0.0	-	-	-	O	-	-	-	Psort location Cytoplasmic, score 9.97
APPACOFM_00458	3.5e-93	-	-	-	-	-	-	-	-
APPACOFM_00459	2.26e-133	-	-	-	S	-	-	-	Rhs element Vgr protein
APPACOFM_00460	7.14e-264	-	-	-	S	-	-	-	Rhs element Vgr protein
APPACOFM_00461	0.0	-	-	-	-	-	-	-	-
APPACOFM_00462	3.97e-102	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_00463	0.0	-	-	-	S	-	-	-	Family of unknown function (DUF5458)
APPACOFM_00464	4.87e-118	-	-	-	M	-	-	-	RHS repeat-associated core domain
APPACOFM_00465	0.0	-	-	-	M	-	-	-	RHS repeat-associated core domain
APPACOFM_00469	3.64e-73	-	-	-	D	-	-	-	AAA ATPase domain
APPACOFM_00470	5.55e-126	-	-	-	S	-	-	-	Protein of unknown function DUF262
APPACOFM_00471	2.98e-95	-	-	-	M	-	-	-	RHS repeat-associated core domain
APPACOFM_00472	3.27e-133	-	-	-	M	-	-	-	RHS repeat-associated core domain
APPACOFM_00473	0.0	-	-	-	M	-	-	-	RHS repeat-associated core domain
APPACOFM_00474	1.98e-91	-	-	-	S	-	-	-	NTF2 fold immunity protein
APPACOFM_00476	3.63e-197	-	-	-	-	-	-	-	-
APPACOFM_00477	0.0	-	-	-	-	-	-	-	-
APPACOFM_00478	1.27e-288	-	-	-	S	-	-	-	AAA domain, putative AbiEii toxin, Type IV TA system
APPACOFM_00479	3.43e-92	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_00481	8.47e-240	-	-	-	-	-	-	-	-
APPACOFM_00482	6.3e-145	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
APPACOFM_00483	9.31e-273	darB	2.3.1.180	-	H	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal
APPACOFM_00484	8.56e-129	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
APPACOFM_00485	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
APPACOFM_00486	8.17e-302	-	-	-	T	ko:K07713	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Sigma-54 interaction domain
APPACOFM_00487	0.0	-	-	-	S	-	-	-	COG NOG09947 non supervised orthologous group
APPACOFM_00488	6e-59	-	-	-	S	-	-	-	Protein of unknown function (DUF4099)
APPACOFM_00489	0.0	-	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	COG0550 Topoisomerase IA
APPACOFM_00490	1.75e-35	-	-	-	-	-	-	-	-
APPACOFM_00491	1.55e-165	-	-	-	S	-	-	-	PRTRC system protein E
APPACOFM_00492	1.55e-46	-	-	-	S	-	-	-	PRTRC system protein C
APPACOFM_00493	3.29e-71	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_00494	2.53e-182	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_00495	2.11e-177	-	-	-	S	-	-	-	PRTRC system protein B
APPACOFM_00496	7.48e-189	-	-	-	H	-	-	-	PRTRC system ThiF family protein
APPACOFM_00497	5.44e-165	-	-	-	S	-	-	-	OST-HTH/LOTUS domain
APPACOFM_00498	5.46e-72	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_00499	1.5e-203	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_00500	1.04e-64	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_00501	1.29e-64	-	-	-	S	-	-	-	COG NOG35747 non supervised orthologous group
APPACOFM_00503	1.77e-121	-	-	-	S	-	-	-	Domain of unknown function (DUF4121)
APPACOFM_00504	1.01e-55	-	-	-	S	-	-	-	Domain of unknown function (DUF4121)
APPACOFM_00505	3.76e-212	-	-	-	L	-	-	-	CHC2 zinc finger
APPACOFM_00507	3.11e-290	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
APPACOFM_00508	2.14e-211	-	-	-	-	-	-	-	-
APPACOFM_00509	0.0	-	-	-	-	-	-	-	-
APPACOFM_00510	3.08e-267	-	-	-	-	-	-	-	-
APPACOFM_00511	1.67e-252	-	-	-	S	-	-	-	COG NOG32009 non supervised orthologous group
APPACOFM_00512	0.0	-	-	-	S	-	-	-	Major fimbrial subunit protein type IV, Fimbrillin, C-terminal
APPACOFM_00513	0.0	-	-	-	U	-	-	-	COG0457 FOG TPR repeat
APPACOFM_00514	2.1e-150	-	-	-	M	-	-	-	Protein of unknown function (DUF3575)
APPACOFM_00517	0.0	-	-	-	G	-	-	-	alpha-galactosidase
APPACOFM_00518	3.61e-315	-	-	-	S	-	-	-	tetratricopeptide repeat
APPACOFM_00519	6.55e-224	-	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	COG0226 ABC-type phosphate transport system, periplasmic component
APPACOFM_00520	2.62e-65	tonB2	-	-	U	ko:K03832	-	ko00000,ko02000	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
APPACOFM_00521	1.2e-104	tonB2	-	-	U	ko:K03832	-	ko00000,ko02000	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
APPACOFM_00522	1.96e-145	exbD2	-	-	U	-	-	-	Biopolymer transport protein ExbD/TolR
APPACOFM_00523	2.42e-85	exbD1	-	-	U	-	-	-	Biopolymer transport protein ExbD/TolR
APPACOFM_00524	1.8e-21	exbD1	-	-	U	-	-	-	Biopolymer transport protein ExbD/TolR
APPACOFM_00525	5.35e-176	exbB	-	-	U	ko:K03561	-	ko00000,ko02000	MotA TolQ ExbB proton channel family
APPACOFM_00526	6.49e-94	-	-	-	-	-	-	-	-
APPACOFM_00530	1.77e-177	-	-	-	L	-	-	-	Integrase core domain
APPACOFM_00531	2.41e-84	-	-	-	L	ko:K07483	-	ko00000	COG2963 Transposase and inactivated derivatives
APPACOFM_00532	3.83e-173	-	-	-	-	-	-	-	-
APPACOFM_00533	1.58e-152	-	-	-	S	-	-	-	Outer membrane protein beta-barrel domain
APPACOFM_00534	3.25e-112	-	-	-	-	-	-	-	-
APPACOFM_00535	2.51e-297	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
APPACOFM_00536	7.02e-289	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
APPACOFM_00537	6.14e-184	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_00538	1.04e-68	-	-	-	L	-	-	-	Helix-turn-helix domain
APPACOFM_00539	1.22e-292	-	-	-	S	-	-	-	COG NOG11635 non supervised orthologous group
APPACOFM_00540	4.64e-198	-	-	-	L	-	-	-	COG NOG08810 non supervised orthologous group
APPACOFM_00541	2.79e-274	-	-	-	L	-	-	-	plasmid recombination enzyme
APPACOFM_00542	5.96e-288	-	-	-	V	-	-	-	AAA domain (dynein-related subfamily)
APPACOFM_00543	2.41e-196	-	-	-	V	ko:K19147	-	ko00000,ko02048	McrBC 5-methylcytosine restriction system component
APPACOFM_00544	1.03e-147	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
APPACOFM_00545	9.73e-87	-	-	-	L	-	-	-	restriction endonuclease
APPACOFM_00546	0.0	-	-	-	L	-	-	-	Eco57I restriction-modification methylase
APPACOFM_00547	1.6e-185	-	-	-	L	-	-	-	restriction
APPACOFM_00548	1.36e-94	-	-	-	K	-	-	-	Nucleotidyl transferase AbiEii toxin, Type IV TA system
APPACOFM_00549	3.94e-47	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
APPACOFM_00551	1.36e-245	gpr	-	-	C	ko:K19265	-	ko00000,ko01000	Oxidoreductase, aldo keto reductase family protein
APPACOFM_00552	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
APPACOFM_00553	3.04e-194	algI	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_00554	6.39e-80	algI	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_00555	3.2e-38	algI	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_00556	1.3e-211	-	-	-	E	-	-	-	COG NOG14456 non supervised orthologous group
APPACOFM_00557	0.0	-	-	-	E	-	-	-	COG COG2755 Lysophospholipase L1 and related esterases
APPACOFM_00558	3.76e-67	-	-	-	E	-	-	-	COG NOG19114 non supervised orthologous group
APPACOFM_00559	0.0	czcA	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
APPACOFM_00560	4.17e-237	-	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
APPACOFM_00561	2.55e-305	-	-	-	MU	-	-	-	Psort location OuterMembrane, score
APPACOFM_00562	2.49e-145	-	-	-	K	-	-	-	transcriptional regulator, TetR family
APPACOFM_00563	0.0	hutH	4.3.1.3	-	E	ko:K01745	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Histidine ammonia-lyase
APPACOFM_00564	1.43e-134	fchA	-	-	E	-	-	-	COG3404 Methenyl tetrahydrofolate cyclohydrolase
APPACOFM_00565	9.87e-301	hutI	3.5.2.7	-	F	ko:K01468	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Imidazolone-5-propionate hydrolase
APPACOFM_00566	1.08e-213	ftcD	2.1.2.5, 4.3.1.4	-	E	ko:K00603,ko:K13990	ko00340,ko00670,ko01100,map00340,map00670,map01100	ko00000,ko00001,ko01000,ko03036,ko04147	Glutamate formiminotransferase
APPACOFM_00567	0.0	hutU	4.2.1.49	-	H	ko:K01712	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
APPACOFM_00568	3.04e-156	-	-	-	S	-	-	-	COG NOG29571 non supervised orthologous group
APPACOFM_00569	0.0	mutS_2	-	-	L	-	-	-	DNA mismatch repair protein MutS
APPACOFM_00570	3.52e-118	-	-	-	S	-	-	-	COG NOG27987 non supervised orthologous group
APPACOFM_00571	3e-89	-	-	-	S	-	-	-	COG NOG31702 non supervised orthologous group
APPACOFM_00572	8.85e-102	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
APPACOFM_00573	6.88e-232	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
APPACOFM_00574	2.53e-140	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
APPACOFM_00575	7.13e-87	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
APPACOFM_00576	1.77e-81	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
APPACOFM_00577	1.06e-18	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
APPACOFM_00578	1.98e-44	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
APPACOFM_00579	1.91e-194	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Psort location Cytoplasmic, score
APPACOFM_00580	2.69e-311	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
APPACOFM_00581	3.46e-94	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
APPACOFM_00582	2.9e-31	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	50S ribosomal protein L30
APPACOFM_00583	1.29e-112	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
APPACOFM_00584	4.05e-70	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
APPACOFM_00585	5.81e-131	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
APPACOFM_00586	5.6e-46	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
APPACOFM_00587	2.73e-61	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
APPACOFM_00588	8.57e-122	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
APPACOFM_00589	2.35e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
APPACOFM_00590	3.37e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
APPACOFM_00591	1.13e-52	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
APPACOFM_00592	1.75e-35	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
APPACOFM_00593	9.31e-97	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
APPACOFM_00594	3.11e-164	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
APPACOFM_00595	2.53e-88	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
APPACOFM_00596	5.19e-59	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
APPACOFM_00597	5.46e-194	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
APPACOFM_00598	1.55e-61	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
APPACOFM_00599	6.14e-140	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
APPACOFM_00600	3.88e-146	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
APPACOFM_00601	6.63e-63	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
APPACOFM_00602	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
APPACOFM_00603	1.89e-105	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
APPACOFM_00604	4.76e-87	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
APPACOFM_00605	6.63e-63	-	-	-	T	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_00606	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
APPACOFM_00607	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
APPACOFM_00608	1.78e-71	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
APPACOFM_00609	2.83e-116	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L10
APPACOFM_00610	8.31e-159	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
APPACOFM_00611	7.31e-100	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
APPACOFM_00612	2.04e-122	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
APPACOFM_00613	1.04e-37	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
APPACOFM_00615	3.77e-291	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
APPACOFM_00620	3.07e-58	raiA	-	-	J	ko:K05808	-	ko00000,ko03009	Ribosomal subunit interface protein
APPACOFM_00621	3.19e-207	xerC	-	-	D	ko:K03733	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
APPACOFM_00622	6.01e-33	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
APPACOFM_00623	0.0	-	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
APPACOFM_00624	4.59e-96	dapH	-	-	S	-	-	-	Bacterial transferase hexapeptide repeat protein
APPACOFM_00626	6.5e-288	-	-	-	CO	-	-	-	COG NOG23392 non supervised orthologous group
APPACOFM_00627	4.87e-296	-	-	-	CO	-	-	-	COG NOG24773 non supervised orthologous group
APPACOFM_00628	5.32e-309	waaA	2.4.99.12, 2.4.99.13, 2.4.99.14, 2.4.99.15	GT30	M	ko:K02527	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	Psort location Cytoplasmic, score 8.96
APPACOFM_00629	0.0	gltX	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
APPACOFM_00630	0.0	-	-	-	S	ko:K07037	-	ko00000	7TM receptor with intracellular HD hydrolase
APPACOFM_00631	1.1e-112	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
APPACOFM_00632	0.0	-	-	-	G	-	-	-	Domain of unknown function (DUF4091)
APPACOFM_00633	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
APPACOFM_00634	1.93e-96	-	-	-	M	-	-	-	COG NOG27749 non supervised orthologous group
APPACOFM_00635	1.48e-249	-	-	-	S	-	-	-	SMI1-KNR4 cell-wall
APPACOFM_00636	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 9.97
APPACOFM_00637	2.51e-283	dcuB	-	-	S	ko:K07791,ko:K07792	ko02020,map02020	ko00000,ko00001,ko02000	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_00638	5.99e-244	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the asparaginase 1 family
APPACOFM_00639	6.14e-15	-	-	-	M	-	-	-	Phosphate-selective porin O and P
APPACOFM_00640	2.25e-259	-	-	-	M	-	-	-	Phosphate-selective porin O and P
APPACOFM_00641	9.33e-48	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_00642	1.05e-132	yvqK	2.5.1.17	-	S	ko:K00798	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Conserved protein
APPACOFM_00643	1.19e-149	-	-	-	S	-	-	-	COG NOG23394 non supervised orthologous group
APPACOFM_00644	3.82e-157	-	-	-	M	ko:K03832	-	ko00000,ko02000	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
APPACOFM_00645	1.61e-293	-	-	-	L	-	-	-	COG3328 Transposase and inactivated derivatives
APPACOFM_00653	2.97e-127	-	-	-	-	-	-	-	-
APPACOFM_00654	0.0	-	2.7.11.1	-	KLMT	ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
APPACOFM_00655	5.04e-49	-	2.7.11.1	-	KLMT	ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
APPACOFM_00656	2.61e-127	-	-	-	T	-	-	-	ATPase activity
APPACOFM_00657	0.0	-	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
APPACOFM_00658	0.0	-	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	Serine/threonine phosphatases, family 2C, catalytic domain
APPACOFM_00659	4.6e-138	-	-	-	T	-	-	-	Inner membrane component of T3SS, cytoplasmic domain
APPACOFM_00660	0.0	-	-	-	OT	-	-	-	Forkhead associated domain
APPACOFM_00662	0.0	-	-	-	S	-	-	-	Domain of unknonw function from B. Theta Gene description (DUF3874)
APPACOFM_00663	3.3e-262	-	-	-	S	-	-	-	UPF0283 membrane protein
APPACOFM_00664	0.0	-	-	-	S	-	-	-	Dynamin family
APPACOFM_00665	1.28e-117	-	-	-	K	ko:K03088	-	ko00000,ko03021	Outer membrane protein beta-barrel domain
APPACOFM_00666	9.17e-243	-	-	-	K	ko:K03088	-	ko00000,ko03021	Outer membrane protein beta-barrel domain
APPACOFM_00667	1.2e-128	-	-	-	H	-	-	-	Methyltransferase domain
APPACOFM_00668	2.17e-286	-	-	-	S	ko:K07148	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_00669	3.89e-226	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
APPACOFM_00670	4.51e-47	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
APPACOFM_00671	3.33e-174	-	-	-	-	-	-	-	-
APPACOFM_00673	7.22e-142	-	-	-	-	-	-	-	-
APPACOFM_00674	1.01e-204	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_00675	6.27e-291	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_00676	2.49e-228	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_00677	0.0	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_00678	8.24e-75	-	-	-	S	-	-	-	repeat protein
APPACOFM_00679	1.17e-105	-	-	-	-	-	-	-	-
APPACOFM_00680	9.45e-181	-	-	-	L	-	-	-	Topoisomerase DNA binding C4 zinc finger
APPACOFM_00681	3.05e-193	-	-	-	K	-	-	-	Fic/DOC family
APPACOFM_00683	3.21e-268	manC	2.7.7.13	-	M	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	ko00000,ko00001,ko00002,ko01000	mannose-1-phosphate guanylyltransferase
APPACOFM_00684	0.0	-	-	-	IQ	ko:K00666	-	ko00000,ko01000,ko01004	Psort location Cytoplasmic, score 9.97
APPACOFM_00685	9.42e-74	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
APPACOFM_00686	3.49e-46	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
APPACOFM_00688	0.0	-	-	-	S	-	-	-	TonB-dependent Receptor Plug Domain
APPACOFM_00689	1.68e-55	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
APPACOFM_00690	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
APPACOFM_00691	1.24e-120	-	-	-	P	ko:K07240	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score
APPACOFM_00692	2.99e-122	-	-	-	P	ko:K07240	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score
APPACOFM_00693	0.0	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
APPACOFM_00694	4.68e-153	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	uracil phosphoribosyltransferase
APPACOFM_00695	4e-174	-	-	-	K	-	-	-	methylphosphotriester-DNA alkyltransferase and transcriptional regulator (AraC XylS family)
APPACOFM_00696	0.0	-	-	-	EGP	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_00697	1.08e-247	-	-	-	V	ko:K03543	-	ko00000,ko00002,ko02000	Auxiliary transport protein, membrane fusion protein (MFP) family protein
APPACOFM_00698	0.0	-	-	-	MU	-	-	-	Psort location OuterMembrane, score
APPACOFM_00699	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_00700	1.14e-75	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_00701	0.0	ahcY	3.3.1.1	-	H	ko:K01251	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
APPACOFM_00702	2.6e-296	-	-	-	T	-	-	-	Psort location CytoplasmicMembrane, score 7.88
APPACOFM_00703	0.0	prc	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
APPACOFM_00704	9.69e-227	-	-	-	G	-	-	-	Kinase, PfkB family
APPACOFM_00707	5.27e-125	-	-	-	K	ko:K02529,ko:K05499	-	ko00000,ko03000	PFAM periplasmic binding protein LacI transcriptional regulator
APPACOFM_00708	8.46e-283	-	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
APPACOFM_00709	3.55e-240	-	-	-	G	-	-	-	alpha-L-rhamnosidase
APPACOFM_00710	1.09e-100	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl-hydrolase 97 N-terminal
APPACOFM_00711	7.13e-55	-	-	-	G	-	-	-	Glycosyl-hydrolase 97 C-terminal, oligomerisation
APPACOFM_00715	1.31e-79	-	-	-	F	ko:K21572	-	ko00000,ko02000	SusD family
APPACOFM_00716	2.58e-195	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_00718	0.0	-	-	-	C	-	-	-	FAD dependent oxidoreductase
APPACOFM_00720	6.4e-285	-	-	-	E	-	-	-	Sodium:solute symporter family
APPACOFM_00721	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 3 family
APPACOFM_00722	2.7e-170	comF	2.4.2.14	-	S	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	ComF family
APPACOFM_00723	9.07e-199	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
APPACOFM_00724	0.0	-	-	-	-	-	-	-	-
APPACOFM_00725	6.24e-219	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
APPACOFM_00726	4.37e-214	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
APPACOFM_00727	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_00728	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	SusD family
APPACOFM_00729	0.0	-	-	-	G	-	-	-	Domain of unknown function (DUF4978)
APPACOFM_00730	2.01e-244	-	-	-	F	-	-	-	Inosine-uridine preferring nucleoside hydrolase
APPACOFM_00731	1.19e-234	-	-	-	G	ko:K05340	-	ko00000,ko02000	COG NOG04879 non supervised orthologous group
APPACOFM_00732	0.0	-	-	-	S	-	-	-	phosphatase family
APPACOFM_00733	0.0	ahpF	-	-	C	ko:K03387	-	ko00000,ko01000	alkyl hydroperoxide reductase subunit F
APPACOFM_00734	7.09e-136	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Psort location Cytoplasmic, score
APPACOFM_00735	0.0	-	-	-	E	ko:K03307	-	ko00000	alkaline phosphatase synthesis sensor protein phoR K07636
APPACOFM_00736	1.09e-222	-	4.3.3.7	-	H	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
APPACOFM_00737	1.46e-128	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
APPACOFM_00739	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat protein
APPACOFM_00740	0.0	-	-	-	H	-	-	-	Psort location OuterMembrane, score
APPACOFM_00741	0.0	-	-	-	H	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_00742	0.0	-	-	-	P	-	-	-	SusD family
APPACOFM_00743	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_00744	0.0	-	-	-	F	ko:K21572	-	ko00000,ko02000	SusD family
APPACOFM_00745	0.0	-	-	-	S	-	-	-	Putative binding domain, N-terminal
APPACOFM_00746	0.0	-	-	-	U	-	-	-	Putative binding domain, N-terminal
APPACOFM_00747	4.67e-283	-	-	-	G	-	-	-	Domain of unknown function (DUF4971)
APPACOFM_00748	8.66e-255	-	3.2.1.14	GH18	G	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Glyco_18
APPACOFM_00749	0.0	-	-	-	T	-	-	-	COG COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
APPACOFM_00750	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
APPACOFM_00751	0.0	-	-	-	S	-	-	-	COG NOG28036 non supervised orthologous group
APPACOFM_00752	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Psort location Cytoplasmic, score
APPACOFM_00753	9.33e-49	hupB	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
APPACOFM_00754	6.51e-206	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_00755	6.62e-257	-	-	-	L	-	-	-	Endonuclease Exonuclease phosphatase family
APPACOFM_00756	0.0	dcp	3.4.15.5	-	E	ko:K01284	-	ko00000,ko01000,ko01002	Peptidase family M3
APPACOFM_00757	0.0	secD	-	-	U	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
APPACOFM_00759	0.0	porA	1.2.7.11, 1.2.7.3	-	C	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	2-oxoacid acceptor oxidoreductase, alpha subunit
APPACOFM_00760	2.28e-249	oorB	1.2.7.11, 1.2.7.3	-	C	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin
APPACOFM_00761	4.04e-284	lolE	-	-	M	ko:K09808,ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4591 ABC-type transport system, involved in lipoprotein release, permease component
APPACOFM_00762	5.86e-68	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
APPACOFM_00763	7.82e-154	mdmC	2.1.1.104	-	S	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
APPACOFM_00764	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Pyruvate kinase
APPACOFM_00765	9.8e-97	aroQ	4.2.1.10	-	E	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a trans-dehydration via an enolate intermediate
APPACOFM_00766	1.67e-222	xerC	-	-	D	ko:K04763	-	ko00000,ko03036	Tyrosine recombinase XerC
APPACOFM_00767	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat protein
APPACOFM_00768	3.7e-259	-	-	-	CO	-	-	-	AhpC TSA family
APPACOFM_00769	0.0	comM	-	-	O	ko:K07391	-	ko00000	Magnesium chelatase, subunit ChlI
APPACOFM_00770	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat protein
APPACOFM_00771	3.04e-301	-	-	-	S	-	-	-	aa) fasta scores E()
APPACOFM_00772	4.82e-256	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Converts alpha-aldose to the beta-anomer
APPACOFM_00773	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
APPACOFM_00774	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
APPACOFM_00775	0.0	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
APPACOFM_00777	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	glycosyl hydrolase, family 3
APPACOFM_00778	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 2 family
APPACOFM_00779	1.58e-304	-	-	-	S	-	-	-	Domain of unknown function
APPACOFM_00780	3.28e-300	-	-	-	S	-	-	-	Domain of unknown function (DUF5126)
APPACOFM_00781	0.0	-	-	-	P	ko:K21572	-	ko00000,ko02000	non supervised orthologous group
APPACOFM_00782	0.0	-	-	-	H	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_00783	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
APPACOFM_00784	3.78e-302	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
APPACOFM_00785	1.04e-289	-	-	-	M	-	-	-	Psort location OuterMembrane, score
APPACOFM_00786	0.0	-	-	-	DM	-	-	-	Chain length determinant protein
APPACOFM_00787	3.51e-181	-	-	-	M	ko:K01991	ko02026,map02026	ko00000,ko00001,ko02000	COG1596 Periplasmic protein involved in polysaccharide export
APPACOFM_00788	1.91e-283	-	2.4.1.348	GT4	M	ko:K12995	-	ko00000,ko01000,ko01003,ko01005	Glycosyl transferase 4-like
APPACOFM_00789	5e-277	-	-	-	H	-	-	-	Glycosyl transferases group 1
APPACOFM_00790	1.03e-285	-	-	-	M	-	-	-	Glycosyltransferase, group 1 family protein
APPACOFM_00791	2.05e-296	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_00792	4.4e-245	-	-	-	M	-	-	-	Glycosyltransferase like family 2
APPACOFM_00793	2.55e-158	-	-	-	I	-	-	-	Acyltransferase family
APPACOFM_00794	1.23e-75	-	-	-	I	-	-	-	Acyltransferase family
APPACOFM_00795	3.78e-217	-	-	-	S	-	-	-	Core-2/I-Branching enzyme
APPACOFM_00796	1.22e-219	-	-	-	S	-	-	-	Core-2/I-Branching enzyme
APPACOFM_00797	1.06e-229	-	-	-	M	-	-	-	Capsular polysaccharide synthesis protein
APPACOFM_00798	1.66e-97	-	-	-	M	-	-	-	Glycosyl transferase family 8
APPACOFM_00799	5.72e-117	-	-	-	M	-	-	-	Glycosyl transferase family 8
APPACOFM_00800	4.94e-155	-	-	-	S	-	-	-	Glycosyltransferase, group 2 family protein
APPACOFM_00801	1.9e-126	-	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Bacterial transferase hexapeptide (six repeats)
APPACOFM_00802	1.36e-241	-	-	-	M	-	-	-	Glycosyltransferase like family 2
APPACOFM_00803	2.63e-142	-	-	-	S	-	-	-	Bacterial transferase hexapeptide (six repeats)
APPACOFM_00804	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_00805	0.0	-	-	-	M	-	-	-	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
APPACOFM_00806	5.87e-256	-	-	-	M	-	-	-	Male sterility protein
APPACOFM_00807	4.15e-171	ispD2	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
APPACOFM_00808	2.44e-242	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family
APPACOFM_00809	3.11e-16	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
APPACOFM_00810	1.51e-112	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
APPACOFM_00811	1.76e-164	-	-	-	S	-	-	-	WbqC-like protein family
APPACOFM_00812	5.8e-271	-	2.6.1.33	-	E	ko:K20429	-	ko00000,ko01000	Belongs to the DegT DnrJ EryC1 family
APPACOFM_00813	1.36e-112	-	-	-	K	-	-	-	KOW (Kyprides, Ouzounis, Woese) motif.
APPACOFM_00814	3.6e-241	-	5.1.3.26	-	M	ko:K19997	-	ko00000,ko01000	Male sterility protein
APPACOFM_00815	1.91e-250	mraY2	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_00816	1.61e-221	-	-	-	K	-	-	-	Helix-turn-helix domain
APPACOFM_00817	6.26e-281	-	-	-	L	-	-	-	Phage integrase SAM-like domain
APPACOFM_00818	0.0	-	-	-	G	-	-	-	exo-alpha-(2->6)-sialidase activity
APPACOFM_00819	0.0	-	-	-	P	ko:K21572	-	ko00000,ko02000	non supervised orthologous group
APPACOFM_00820	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_00821	4.98e-213	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 43 family
APPACOFM_00822	4.07e-28	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 43 family
APPACOFM_00823	0.0	-	-	-	CO	-	-	-	amine dehydrogenase activity
APPACOFM_00824	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
APPACOFM_00825	2.4e-104	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 43 family
APPACOFM_00826	8.13e-73	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 43 family
APPACOFM_00827	0.0	-	-	-	Q	-	-	-	4-hydroxyphenylacetate
APPACOFM_00829	5.57e-249	arbA_2	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	hydrolase, family 43
APPACOFM_00830	1.3e-271	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 43 family
APPACOFM_00831	8.02e-129	-	-	-	S	-	-	-	Domain of unknown function
APPACOFM_00832	7.27e-155	-	-	-	S	-	-	-	Domain of unknown function
APPACOFM_00833	8.08e-307	-	-	-	S	-	-	-	Domain of unknown function (DUF5126)
APPACOFM_00834	0.0	-	-	-	P	ko:K21572	-	ko00000,ko02000	non supervised orthologous group
APPACOFM_00835	1.45e-149	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_00836	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_00837	0.0	-	-	-	M	-	-	-	Glycosyltransferase WbsX
APPACOFM_00838	0.0	-	2.8.2.1	-	M	ko:K01014	ko05204,map05204	ko00000,ko00001,ko01000	transferase activity, transferring glycosyl groups
APPACOFM_00839	0.0	-	3.2.1.45	GH116	G	ko:K17108	ko00511,ko00600,ko01100,map00511,map00600,map01100	ko00000,ko00001,ko01000	Pfam:GBA2_N
APPACOFM_00840	0.0	-	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
APPACOFM_00841	3.23e-216	-	-	-	K	-	-	-	Transcriptional regulator, AraC family
APPACOFM_00842	0.0	-	-	-	S	ko:K09955	-	ko00000	Domain of unknown function
APPACOFM_00843	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 43 family
APPACOFM_00844	1.29e-302	-	-	-	G	-	-	-	Glycosyl Hydrolase Family 88
APPACOFM_00845	0.0	-	-	-	P	-	-	-	Protein of unknown function (DUF229)
APPACOFM_00846	3.9e-244	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
APPACOFM_00847	1.78e-307	-	-	-	O	-	-	-	protein conserved in bacteria
APPACOFM_00848	2.14e-157	-	-	-	S	-	-	-	Domain of unknown function
APPACOFM_00849	1.53e-311	-	-	-	S	-	-	-	Domain of unknown function (DUF5126)
APPACOFM_00850	0.0	-	-	-	P	ko:K21572	-	ko00000,ko02000	non supervised orthologous group
APPACOFM_00851	0.0	-	-	-	H	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_00852	1.13e-134	-	-	-	G	-	-	-	unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
APPACOFM_00853	3.05e-113	-	-	-	G	-	-	-	unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
APPACOFM_00854	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 2 family
APPACOFM_00855	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
APPACOFM_00856	1.7e-301	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
APPACOFM_00857	5.64e-206	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
APPACOFM_00858	0.0	-	-	-	C	ko:K09181	-	ko00000	CoA binding domain protein
APPACOFM_00860	2.18e-28	-	-	-	M	-	-	-	COG COG3209 Rhs family protein
APPACOFM_00862	2.64e-281	-	-	-	M	-	-	-	COG COG3209 Rhs family protein
APPACOFM_00864	5.9e-62	-	-	-	M	-	-	-	self proteolysis
APPACOFM_00865	1.41e-10	-	-	-	-	-	-	-	-
APPACOFM_00866	2.23e-113	-	-	-	L	-	-	-	COG NOG31286 non supervised orthologous group
APPACOFM_00867	1.17e-204	-	-	-	L	-	-	-	Domain of unknown function (DUF4373)
APPACOFM_00868	6.26e-20	-	-	-	-	-	-	-	-
APPACOFM_00869	1.9e-173	-	-	-	K	-	-	-	Peptidase S24-like
APPACOFM_00870	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
APPACOFM_00871	1.09e-90	-	-	-	S	-	-	-	ORF6N domain
APPACOFM_00872	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_00873	1.06e-256	-	-	-	-	-	-	-	-
APPACOFM_00874	1.53e-288	-	-	-	M	-	-	-	Glycosyl transferase 4-like domain
APPACOFM_00875	4.05e-266	-	-	-	M	-	-	-	Glycosyl transferases group 1
APPACOFM_00876	7.59e-278	-	-	-	M	-	-	-	Glycosyl transferases group 1
APPACOFM_00877	1.61e-131	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_00878	7.45e-167	-	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
APPACOFM_00879	0.0	bepE_1	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
APPACOFM_00880	5.19e-308	oprM_1	-	-	MU	-	-	-	Efflux transporter, outer membrane factor lipoprotein, NodT family
APPACOFM_00881	6.5e-269	epsC	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	UDP-N-acetylglucosamine 2-epimerase
APPACOFM_00882	3.26e-295	-	1.1.1.336	-	M	ko:K02472	ko00520,ko05111,map00520,map05111	ko00000,ko00001,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
APPACOFM_00883	0.0	-	-	-	M	-	-	-	Glycosyltransferase, group 1 family protein
APPACOFM_00884	1.02e-182	-	-	-	S	-	-	-	Glycosyltransferase, group 2 family protein
APPACOFM_00885	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 115
APPACOFM_00886	0.0	-	-	-	M	-	-	-	Belongs to the glycosyl hydrolase 43 family
APPACOFM_00888	5.17e-218	-	-	-	E	-	-	-	COG NOG17363 non supervised orthologous group
APPACOFM_00889	0.0	-	-	-	G	-	-	-	unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
APPACOFM_00890	3.8e-292	-	-	-	G	-	-	-	unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
APPACOFM_00891	0.0	-	4.2.2.5	PL8	N	ko:K19049	-	ko00000,ko01000	Polysaccharide lyase family 8, super-sandwich domain
APPACOFM_00892	4.18e-24	-	-	-	S	-	-	-	Domain of unknown function
APPACOFM_00893	1.12e-305	-	-	-	S	-	-	-	Domain of unknown function (DUF5126)
APPACOFM_00894	0.0	-	-	-	P	ko:K21572	-	ko00000,ko02000	non supervised orthologous group
APPACOFM_00895	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_00896	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
APPACOFM_00897	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	COG COG3669 Alpha-L-fucosidase
APPACOFM_00898	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
APPACOFM_00899	1.25e-195	-	-	-	Q	-	-	-	COG NOG10855 non supervised orthologous group
APPACOFM_00900	1.15e-78	-	-	-	K	ko:K07506,ko:K13652	-	ko00000,ko03000	Bacterial regulatory helix-turn-helix proteins, AraC family
APPACOFM_00901	1.4e-44	-	-	-	-	-	-	-	-
APPACOFM_00902	7.18e-170	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
APPACOFM_00903	6.64e-136	fklB	5.2.1.8	-	G	ko:K03772,ko:K03773	-	ko00000,ko01000,ko03110	Peptidyl-prolyl cis-trans isomerase
APPACOFM_00904	1.7e-201	-	5.2.1.8	-	M	ko:K03772,ko:K03773	-	ko00000,ko01000,ko03110	Peptidyl-prolyl cis-trans isomerase
APPACOFM_00905	3.43e-106	asnC	-	-	K	ko:K03718	-	ko00000,ko03000	Transcriptional regulator, AsnC family
APPACOFM_00906	1.27e-70	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
APPACOFM_00908	4.23e-65	-	-	-	-	-	-	-	-
APPACOFM_00909	5.79e-12	-	-	-	-	-	-	-	-
APPACOFM_00911	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_00912	0.0	tetP	-	-	J	ko:K18220	-	br01600,ko00000,ko01504	Translation elongation factor
APPACOFM_00913	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
APPACOFM_00914	7.92e-51	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
APPACOFM_00915	0.0	zraR	-	-	T	ko:K07713	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Sigma-54 interaction domain protein
APPACOFM_00916	1.83e-101	-	-	-	H	-	-	-	dihydrofolate reductase family protein K00287
APPACOFM_00917	7.65e-123	rteC	-	-	S	-	-	-	RteC protein
APPACOFM_00918	3.13e-92	-	-	-	K	-	-	-	COG NOG19120 non supervised orthologous group
APPACOFM_00922	3.45e-101	-	-	-	H	-	-	-	ThiF family
APPACOFM_00923	4.56e-99	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydropteroate synthase
APPACOFM_00924	6.78e-81	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
APPACOFM_00925	6.39e-46	-	-	-	K	-	-	-	DNA binding domain, excisionase family
APPACOFM_00927	1.27e-245	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
APPACOFM_00928	2.89e-130	-	-	-	L	-	-	-	DNA binding domain, excisionase family
APPACOFM_00930	3.48e-83	-	-	-	S	ko:K07133	-	ko00000	Psort location Cytoplasmic, score 8.96
APPACOFM_00931	3.38e-277	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_00934	3.22e-41	-	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Serine/threonine phosphatases, family 2C, catalytic domain
APPACOFM_00935	0.0	-	-	-	S	-	-	-	COG0433 Predicted ATPase
APPACOFM_00936	5.89e-152	-	-	-	-	-	-	-	-
APPACOFM_00937	0.0	-	2.7.11.1	-	KLT	ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
APPACOFM_00938	1.58e-227	-	-	-	-	-	-	-	-
APPACOFM_00939	1.31e-87	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
APPACOFM_00940	1.48e-65	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
APPACOFM_00941	2.12e-296	-	2.1.1.72	-	L	ko:K03427	-	ko00000,ko01000,ko02048	N-6 DNA methylase
APPACOFM_00942	4.85e-32	-	-	-	K	-	-	-	sequence-specific DNA binding
APPACOFM_00943	6.13e-308	-	-	-	D	-	-	-	plasmid recombination enzyme
APPACOFM_00944	7.42e-146	-	-	-	L	-	-	-	COG NOG08810 non supervised orthologous group
APPACOFM_00945	8.39e-112	-	-	-	S	-	-	-	COG NOG11635 non supervised orthologous group
APPACOFM_00946	2.35e-30	-	-	-	L	-	-	-	Helix-turn-helix domain
APPACOFM_00947	2.93e-116	-	-	-	-	-	-	-	-
APPACOFM_00948	1.29e-184	-	-	-	S	-	-	-	Domain of unknown function (DUF4143)
APPACOFM_00950	4.62e-199	-	-	-	L	-	-	-	Phage integrase SAM-like domain
APPACOFM_00951	7.52e-209	-	-	-	K	-	-	-	Transcriptional regulator
APPACOFM_00952	2.23e-96	-	-	-	K	-	-	-	Transcriptional regulator
APPACOFM_00953	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_00954	1.98e-104	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_00955	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_00956	1.38e-196	ddpX	3.4.13.22	-	M	ko:K08641	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
APPACOFM_00957	1.83e-278	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_00958	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Glycosyl hydrolase family 3 C-terminal domain protein
APPACOFM_00960	1.63e-132	-	-	-	K	ko:K03088	-	ko00000,ko03021	RNA polymerase sigma-70 factor
APPACOFM_00961	5.57e-217	-	-	-	PT	-	-	-	Domain of unknown function (DUF4974)
APPACOFM_00962	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_00963	0.0	-	-	-	P	ko:K21572	-	ko00000,ko02000	non supervised orthologous group
APPACOFM_00964	1.77e-53	-	-	-	P	ko:K21572	-	ko00000,ko02000	non supervised orthologous group
APPACOFM_00965	1.88e-222	-	-	-	S	-	-	-	Domain of unknown function (DUF4959)
APPACOFM_00966	0.0	-	-	-	E	-	-	-	COG NOG04153 non supervised orthologous group
APPACOFM_00967	0.0	-	-	-	M	-	-	-	Psort location OuterMembrane, score
APPACOFM_00968	1.97e-230	-	3.1.3.2	-	S	ko:K14379	ko00740,ko01100,ko04142,ko04380,ko05323,map00740,map01100,map04142,map04380,map05323	ko00000,ko00001,ko01000	Purple acid phosphatase
APPACOFM_00969	0.0	mscM	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_00970	3.58e-217	yrbG	-	-	P	ko:K07301	-	ko00000,ko02000	K -dependent Na Ca exchanger
APPACOFM_00971	0.0	-	-	-	S	-	-	-	COG NOG30867 non supervised orthologous group
APPACOFM_00972	2.77e-310	-	-	-	O	-	-	-	protein conserved in bacteria
APPACOFM_00973	3.15e-229	-	-	-	S	-	-	-	Metalloenzyme superfamily
APPACOFM_00974	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_00975	0.0	-	-	-	GM	ko:K21572	-	ko00000,ko02000	Pfam:SusD
APPACOFM_00976	0.0	-	-	-	M	-	-	-	Glycosyl hydrolase family 30 TIM-barrel domain
APPACOFM_00977	1.69e-280	-	-	-	N	-	-	-	domain, Protein
APPACOFM_00978	2.81e-303	-	2.4.1.281	-	G	ko:K16212	-	ko00000,ko01000	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
APPACOFM_00979	0.0	-	-	-	E	-	-	-	Sodium:solute symporter family
APPACOFM_00980	5.21e-283	-	-	-	S	-	-	-	PQQ enzyme repeat protein
APPACOFM_00981	7.4e-288	-	-	-	S	-	-	-	PQQ enzyme repeat protein
APPACOFM_00982	2.05e-138	-	-	-	S	-	-	-	PFAM ORF6N domain
APPACOFM_00983	2.8e-278	yghO	-	-	K	-	-	-	COG NOG07967 non supervised orthologous group
APPACOFM_00984	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	COG0187 Type IIA topoisomerase (DNA gyrase topo II topoisomerase IV) B subunit
APPACOFM_00985	2.25e-105	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
APPACOFM_00986	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
APPACOFM_00987	0.0	-	-	-	H	-	-	-	Outer membrane protein beta-barrel family
APPACOFM_00988	1.41e-119	-	-	-	K	ko:K03088	-	ko00000,ko03021	RNA polymerase sigma-70 factor, ECF subfamily
APPACOFM_00989	6.25e-233	-	-	-	PT	-	-	-	Sigma factor regulatory protein, FecR PupR family
APPACOFM_00990	2.94e-90	-	-	-	-	-	-	-	-
APPACOFM_00991	2.5e-205	-	-	-	S	-	-	-	COG3943 Virulence protein
APPACOFM_00992	1.06e-142	-	-	-	L	-	-	-	DNA-binding protein
APPACOFM_00993	2.39e-110	-	-	-	S	-	-	-	Virulence protein RhuM family
APPACOFM_00995	0.0	-	-	-	M	-	-	-	COG NOG07608 non supervised orthologous group
APPACOFM_00996	6.18e-206	-	-	-	S	-	-	-	Domain of unknown function (DUF4361)
APPACOFM_00997	0.0	-	-	-	P	ko:K21572	-	ko00000,ko02000	Psort location OuterMembrane, score
APPACOFM_00998	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_00999	0.0	-	-	-	S	-	-	-	amine dehydrogenase activity
APPACOFM_01000	0.0	-	-	-	P	-	-	-	TonB-dependent Receptor Plug Domain
APPACOFM_01001	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
APPACOFM_01002	2.81e-231	-	3.2.1.14, 3.2.1.4	GH18,GH5,GH9	G	ko:K01179,ko:K01183	ko00500,ko00520,ko01100,map00500,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 18 family
APPACOFM_01003	0.0	-	-	-	P	-	-	-	Domain of unknown function (DUF4976)
APPACOFM_01004	5.29e-184	-	-	-	L	-	-	-	Integrase core domain
APPACOFM_01005	1.81e-78	-	-	-	-	-	-	-	-
APPACOFM_01006	6.43e-239	-	-	-	K	-	-	-	transcriptional regulator (AraC family)
APPACOFM_01007	4.85e-168	sdhC	-	-	C	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002	Succinate dehydrogenase cytochrome B subunit, b558 family
APPACOFM_01008	0.0	sdhA	1.3.5.1, 1.3.5.4	-	C	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	COG1053 Succinate dehydrogenase fumarate reductase flavoprotein subunit
APPACOFM_01009	5.27e-185	frdB	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	COG0479 Succinate dehydrogenase fumarate reductase Fe-S protein subunit
APPACOFM_01010	4.33e-300	-	-	-	S	-	-	-	protein BT3056 SWALL AAO78162 (EMBL AE016938) (409 aa) fasta scores E()
APPACOFM_01011	0.0	-	-	-	P	-	-	-	Sulfatase
APPACOFM_01012	3.51e-209	-	-	-	K	-	-	-	Transcriptional regulator, AraC family
APPACOFM_01013	5.04e-47	-	-	-	S	-	-	-	COG NOG31846 non supervised orthologous group
APPACOFM_01014	5.49e-176	-	-	-	S	-	-	-	COG NOG26135 non supervised orthologous group
APPACOFM_01015	3.79e-309	-	-	-	M	-	-	-	COG NOG24980 non supervised orthologous group
APPACOFM_01016	2.01e-108	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_01018	2.37e-50	-	-	-	S	-	-	-	Domain of unknown function (DUF4248)
APPACOFM_01019	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
APPACOFM_01020	0.0	-	-	-	S	-	-	-	amine dehydrogenase activity
APPACOFM_01021	9.06e-259	-	-	-	S	-	-	-	amine dehydrogenase activity
APPACOFM_01022	7.44e-232	-	-	-	L	-	-	-	COG COG3547 Transposase and inactivated derivatives
APPACOFM_01023	1.27e-291	-	-	-	M	-	-	-	Protein of unknown function, DUF255
APPACOFM_01024	4.08e-258	dprA	-	-	LU	ko:K04096	-	ko00000	Rossmann fold nucleotide-binding protein involved in DNA uptake
APPACOFM_01025	1.66e-92	-	-	-	S	ko:K07107	-	ko00000,ko01000	acyl-CoA thioester hydrolase, YbgC YbaW family
APPACOFM_01026	4.48e-300	prtC	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Psort location Cytoplasmic, score 8.96
APPACOFM_01027	2.84e-240	dus	-	-	H	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
APPACOFM_01028	9.79e-232	-	-	-	I	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_01029	1.73e-248	-	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	NAD dependent epimerase dehydratase family
APPACOFM_01030	0.0	rnr	-	-	J	ko:K12573,ko:K12585	ko03018,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
APPACOFM_01031	1.44e-114	-	-	-	S	ko:K07005	-	ko00000	Pyridoxamine 5'-phosphate oxidase family protein
APPACOFM_01032	0.0	-	-	-	NU	-	-	-	CotH kinase protein
APPACOFM_01033	4.38e-216	cysK	2.5.1.47	-	E	ko:K01738,ko:K12339	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
APPACOFM_01034	6.48e-80	-	-	-	S	-	-	-	Cupin domain protein
APPACOFM_01035	0.0	-	3.2.1.80	-	M	ko:K03332	ko00051,map00051	ko00000,ko00001,ko01000	Glycosyl hydrolases family 32
APPACOFM_01036	0.0	-	-	-	S	ko:K07133	-	ko00000	ATPase (AAA superfamily)
APPACOFM_01037	1.68e-195	-	-	-	I	-	-	-	COG0657 Esterase lipase
APPACOFM_01038	2.58e-57	-	3.2.1.177	GH31	G	ko:K01811	-	ko00000,ko01000	Domain of unknown function (DUF5110)
APPACOFM_01039	0.0	-	3.2.1.177	GH31	G	ko:K01811	-	ko00000,ko01000	Domain of unknown function (DUF5110)
APPACOFM_01040	0.0	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
APPACOFM_01041	0.0	-	3.2.1.11	GH66	G	ko:K05988	ko00500,map00500	ko00000,ko00001,ko01000	COG NOG34737 non supervised orthologous group
APPACOFM_01042	0.0	-	-	-	S	ko:K21571	-	ko00000	Outer membrane protein SusF_SusE
APPACOFM_01043	0.0	-	-	-	GM	ko:K21572	-	ko00000,ko02000	SusD family
APPACOFM_01044	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_01045	0.0	-	-	-	S	ko:K21557	-	ko00000,ko03000	Psort location Cytoplasmic, score 8.96
APPACOFM_01046	0.0	-	-	-	G	-	-	-	Glycosyl hydrolases family 2, TIM barrel domain
APPACOFM_01047	0.0	-	3.1.6.1	-	P	ko:K01130	ko00140,ko00600,map00140,map00600	ko00000,ko00001,ko01000	COG COG3119 Arylsulfatase A and related enzymes
APPACOFM_01048	2.52e-212	-	-	-	G	-	-	-	Glycosyl hydrolase family 43
APPACOFM_01049	2.06e-42	-	-	-	G	-	-	-	Glycosyl hydrolase family 43
APPACOFM_01050	0.0	-	-	-	P	-	-	-	COG COG3119 Arylsulfatase A and related enzymes
APPACOFM_01051	0.0	-	-	-	G	-	-	-	Alpha-L-arabinofuranosidase C-terminal domain
APPACOFM_01052	0.0	-	-	-	T	-	-	-	Y_Y_Y domain
APPACOFM_01053	9.3e-145	-	-	-	T	-	-	-	Y_Y_Y domain
APPACOFM_01054	4.03e-44	-	-	-	T	-	-	-	Y_Y_Y domain
APPACOFM_01055	2.04e-94	-	-	-	-	-	-	-	-
APPACOFM_01056	4.27e-142	-	-	-	-	-	-	-	-
APPACOFM_01057	7.3e-212	-	-	-	I	-	-	-	Carboxylesterase family
APPACOFM_01058	0.0	-	-	-	M	-	-	-	Sulfatase
APPACOFM_01059	0.0	-	-	-	GM	ko:K21572	-	ko00000,ko02000	COG NOG26302 non supervised orthologous group
APPACOFM_01060	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_01061	1.55e-254	-	-	-	-	-	-	-	-
APPACOFM_01062	0.0	-	3.1.6.1	-	P	ko:K01130	ko00140,ko00600,map00140,map00600	ko00000,ko00001,ko01000	COG COG3119 Arylsulfatase A and related enzymes
APPACOFM_01063	0.0	-	3.1.6.1	-	P	ko:K01130	ko00140,ko00600,map00140,map00600	ko00000,ko00001,ko01000	COG COG3119 Arylsulfatase A and related enzymes
APPACOFM_01064	2.02e-229	abnA	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 43 family
APPACOFM_01065	0.0	-	-	-	P	-	-	-	Psort location Cytoplasmic, score
APPACOFM_01066	1.46e-73	-	-	-	-	-	-	-	-
APPACOFM_01067	4.42e-109	-	-	-	-	-	-	-	-
APPACOFM_01068	0.0	-	-	-	-	-	-	-	-
APPACOFM_01069	0.0	-	-	-	O	ko:K06889	-	ko00000	COG COG1073 Hydrolases of the alpha beta superfamily
APPACOFM_01070	5.58e-270	araJ	-	-	EGP	ko:K08156	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_01071	1.91e-259	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
APPACOFM_01072	1.4e-206	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
APPACOFM_01073	8.22e-213	lgt	-	-	M	-	-	-	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
APPACOFM_01074	1.33e-69	-	2.3.1.28	-	V	ko:K19271	-	br01600,ko00000,ko01000,ko01504	COG4845 Chloramphenicol O-acetyltransferase
APPACOFM_01076	0.0	-	-	-	S	-	-	-	MAC/Perforin domain
APPACOFM_01077	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
APPACOFM_01078	9.89e-212	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
APPACOFM_01079	2.07e-207	rhaR_1	-	-	K	-	-	-	transcriptional regulator (AraC family)
APPACOFM_01080	6.91e-201	eamA	-	-	EG	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_01081	0.0	-	3.1.1.53	-	G	ko:K05970	-	ko00000,ko01000	COG NOG04984 non supervised orthologous group
APPACOFM_01083	5.24e-112	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
APPACOFM_01084	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
APPACOFM_01085	4.24e-218	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
APPACOFM_01086	1.48e-135	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
APPACOFM_01087	5.39e-188	-	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	COG COG1360 Flagellar motor protein
APPACOFM_01088	0.0	-	-	-	G	-	-	-	Alpha-1,2-mannosidase
APPACOFM_01089	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
APPACOFM_01090	0.0	-	3.1.1.53	-	G	ko:K05970	-	ko00000,ko01000	Glycosyl hydrolase family 2, sugar binding domain protein
APPACOFM_01091	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
APPACOFM_01092	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
APPACOFM_01093	0.0	-	3.2.1.51	GH95	G	ko:K15923	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65, N-terminal domain
APPACOFM_01095	4.66e-147	-	-	-	H	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_01096	0.0	-	-	-	H	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_01097	0.0	-	-	-	P	ko:K21572	-	ko00000,ko02000	non supervised orthologous group
APPACOFM_01098	1.07e-103	-	-	-	P	ko:K21572	-	ko00000,ko02000	non supervised orthologous group
APPACOFM_01099	5.47e-293	-	-	-	S	-	-	-	Domain of unknown function (DUF5126)
APPACOFM_01100	0.0	-	-	-	S	-	-	-	Domain of unknown function
APPACOFM_01101	0.0	-	-	-	M	-	-	-	Right handed beta helix region
APPACOFM_01102	7.63e-103	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
APPACOFM_01103	1.73e-45	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
APPACOFM_01104	8.55e-216	-	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	COG0584 Glycerophosphoryl diester phosphodiesterase
APPACOFM_01105	0.0	-	3.2.1.20	GH31	E	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl-hydrolase 97 C-terminal, oligomerisation
APPACOFM_01106	4.29e-226	nadA	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
APPACOFM_01108	1.5e-59	spoU	-	-	J	-	-	-	RNA methylase, SpoU family K00599
APPACOFM_01109	3.39e-38	spoU	-	-	J	-	-	-	RNA methylase, SpoU family K00599
APPACOFM_01110	2.84e-126	-	-	-	S	-	-	-	COG NOG14459 non supervised orthologous group
APPACOFM_01111	0.0	-	-	-	L	-	-	-	Psort location OuterMembrane, score
APPACOFM_01112	3.86e-190	-	-	-	C	-	-	-	radical SAM domain protein
APPACOFM_01113	0.0	-	-	-	P	-	-	-	Psort location Cytoplasmic, score
APPACOFM_01114	9.91e-109	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
APPACOFM_01115	0.0	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
APPACOFM_01116	0.0	-	3.1.1.53	-	S	ko:K05970	-	ko00000,ko01000	Carbohydrate esterase, sialic acid-specific acetylesterase
APPACOFM_01117	8.24e-270	-	-	-	S	-	-	-	COGs COG4299 conserved
APPACOFM_01118	0.0	sulP	-	-	P	ko:K03321	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_01119	3.5e-138	rbr	-	-	C	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_01120	2.28e-58	-	-	-	S	-	-	-	Domain of unknown function (DUF4884)
APPACOFM_01121	1.12e-156	nadB	1.4.3.16	-	H	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of L-aspartate to iminoaspartate
APPACOFM_01122	7.65e-182	nadB	1.4.3.16	-	H	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of L-aspartate to iminoaspartate
APPACOFM_01123	4.97e-79	-	-	-	S	-	-	-	COG NOG29403 non supervised orthologous group
APPACOFM_01124	4.86e-314	lpdA	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3)
APPACOFM_01125	0.0	dacB	3.4.16.4	-	M	ko:K07259	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	COG2027 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4)
APPACOFM_01126	2.02e-290	-	-	-	S	-	-	-	PFAM Formylglycine-generating sulfatase enzyme
APPACOFM_01127	0.0	-	-	-	S	-	-	-	PFAM Formylglycine-generating sulfatase enzyme
APPACOFM_01128	9.2e-138	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70, region 4
APPACOFM_01129	3.69e-143	-	-	-	-	-	-	-	-
APPACOFM_01130	3.83e-177	-	-	-	M	ko:K03832	-	ko00000,ko02000	Gram-negative bacterial TonB protein C-terminal
APPACOFM_01131	0.0	scpC	2.8.3.18, 3.1.2.1	-	C	ko:K01067,ko:K18118	ko00020,ko00620,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00650,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	COG0427 Acetyl-CoA hydrolase
APPACOFM_01132	1.03e-85	-	-	-	-	-	-	-	-
APPACOFM_01133	0.0	miaB	2.8.4.3	-	J	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
APPACOFM_01134	3.27e-167	-	-	-	K	-	-	-	Bacteriophage CI repressor helix-turn-helix domain
APPACOFM_01135	3.32e-72	-	-	-	-	-	-	-	-
APPACOFM_01136	1.47e-212	-	-	-	L	-	-	-	Domain of unknown function (DUF4373)
APPACOFM_01137	1.93e-112	-	-	-	L	-	-	-	COG NOG31286 non supervised orthologous group
APPACOFM_01138	6.46e-126	-	3.5.1.28	-	V	ko:K01447	-	ko00000,ko01000	Psort location Cytoplasmic, score 8.96
APPACOFM_01139	2.42e-11	-	-	-	-	-	-	-	-
APPACOFM_01140	0.0	-	-	-	M	-	-	-	COG3209 Rhs family protein
APPACOFM_01141	0.0	-	-	-	M	-	-	-	COG COG3209 Rhs family protein
APPACOFM_01143	1.06e-74	-	-	-	M	-	-	-	COG COG3209 Rhs family protein
APPACOFM_01144	7.46e-177	-	-	-	M	-	-	-	JAB-like toxin 1
APPACOFM_01145	3.41e-257	-	-	-	S	-	-	-	Immunity protein 65
APPACOFM_01146	9.9e-197	-	-	-	M	-	-	-	COG COG3209 Rhs family protein
APPACOFM_01147	5.91e-46	-	-	-	-	-	-	-	-
APPACOFM_01148	4.8e-221	-	-	-	H	-	-	-	Methyltransferase domain protein
APPACOFM_01149	2.03e-194	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Belongs to the ABC-4 integral membrane protein family. FtsX subfamily
APPACOFM_01150	2.06e-46	fjo13	-	-	S	-	-	-	COG NOG19122 non supervised orthologous group
APPACOFM_01151	6.84e-183	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
APPACOFM_01152	3.46e-121	truB	5.4.99.25	-	J	ko:K03177	-	ko00000,ko01000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
APPACOFM_01153	2.31e-257	queA	2.4.99.17	-	H	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
APPACOFM_01154	3.49e-83	-	-	-	-	-	-	-	-
APPACOFM_01155	7.97e-108	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase
APPACOFM_01156	5.32e-36	-	-	-	-	-	-	-	-
APPACOFM_01158	2.28e-308	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
APPACOFM_01159	0.0	-	-	-	S	-	-	-	tetratricopeptide repeat
APPACOFM_01161	1.37e-221	-	-	-	S	-	-	-	Domain of unknown function (DUF4848)
APPACOFM_01163	1.79e-137	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
APPACOFM_01164	3.51e-164	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
APPACOFM_01165	1.97e-174	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
APPACOFM_01166	4.48e-67	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
APPACOFM_01167	1.92e-64	yidD	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
APPACOFM_01168	1.24e-163	-	-	-	L	ko:K03424	-	ko00000,ko01000	Psort location Cytoplasmic, score 8.96
APPACOFM_01169	2.1e-110	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
APPACOFM_01170	4.4e-165	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
APPACOFM_01173	1.04e-210	kduI	5.3.1.17	-	G	ko:K01815	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
APPACOFM_01174	1.06e-192	idnO	1.1.1.69	-	IQ	ko:K00046	-	ko00000,ko01000	Oxidoreductase, short chain dehydrogenase reductase family protein
APPACOFM_01175	4.91e-304	-	3.1.1.11	-	G	ko:K01051	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	COG NOG24911 non supervised orthologous group
APPACOFM_01176	5.44e-293	-	-	-	-	-	-	-	-
APPACOFM_01177	5.56e-245	-	-	-	S	-	-	-	Putative binding domain, N-terminal
APPACOFM_01178	5.97e-316	-	-	-	S	-	-	-	Domain of unknown function (DUF4302)
APPACOFM_01179	4.76e-213	-	-	-	S	-	-	-	Putative zinc-binding metallo-peptidase
APPACOFM_01180	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	COG NOG28139 non supervised orthologous group
APPACOFM_01181	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_01182	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_01183	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	COG NOG28139 non supervised orthologous group
APPACOFM_01184	2.49e-230	-	-	-	S	-	-	-	Putative zinc-binding metallo-peptidase
APPACOFM_01185	1.76e-300	-	-	-	S	-	-	-	Domain of unknown function (DUF4302)
APPACOFM_01186	4.8e-251	-	-	-	S	-	-	-	Putative binding domain, N-terminal
APPACOFM_01187	2.28e-248	queG	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
APPACOFM_01188	1.04e-154	pgdA_1	-	-	G	-	-	-	Psort location Cytoplasmic, score
APPACOFM_01189	2.16e-32	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_01190	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_01192	9.54e-185	znuC	-	-	P	ko:K09817	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
APPACOFM_01193	1.23e-223	mntA	-	-	P	ko:K09815,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0803 ABC-type metal ion transport system, periplasmic component surface adhesin
APPACOFM_01194	2.71e-177	mnmC	-	-	S	-	-	-	Psort location Cytoplasmic, score
APPACOFM_01195	3.38e-104	yqaA	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.46
APPACOFM_01196	7.21e-237	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_01197	2.87e-308	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
APPACOFM_01198	0.0	pepX2	3.4.14.5	-	E	ko:K01278	ko04974,map04974	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	Peptidase, S9A B C family, catalytic domain protein
APPACOFM_01199	2.74e-307	rlmL	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
APPACOFM_01200	6.78e-217	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 9.97
APPACOFM_01201	0.0	-	-	-	T	-	-	-	Histidine kinase
APPACOFM_01202	1.13e-174	-	-	-	T	ko:K02477	-	ko00000,ko02022	COG3279 Response regulator of the LytR AlgR family
APPACOFM_01203	1.74e-88	-	-	-	S	-	-	-	COG NOG29882 non supervised orthologous group
APPACOFM_01204	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
APPACOFM_01205	1.04e-223	ispB	2.5.1.90	-	H	ko:K02523	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
APPACOFM_01206	1.19e-164	-	-	-	S	-	-	-	Protein of unknown function (DUF1266)
APPACOFM_01207	1.21e-210	deoC	4.1.2.4	-	H	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
APPACOFM_01208	7.63e-74	ypjD	-	-	S	-	-	-	MazG nucleotide pyrophosphohydrolase domain
APPACOFM_01209	3.46e-104	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
APPACOFM_01210	1.77e-177	-	-	-	L	-	-	-	Integrase core domain
APPACOFM_01211	2.41e-84	-	-	-	L	ko:K07483	-	ko00000	COG2963 Transposase and inactivated derivatives
APPACOFM_01212	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
APPACOFM_01213	1.14e-121	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
APPACOFM_01214	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
APPACOFM_01216	2.66e-132	-	-	-	K	ko:K03088	-	ko00000,ko03021	RNA polymerase sigma-70 factor, ECF subfamily
APPACOFM_01217	4.52e-288	-	-	-	PT	-	-	-	Domain of unknown function (DUF4974)
APPACOFM_01218	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_01219	0.0	-	-	-	J	ko:K21572	-	ko00000,ko02000	Pfam:SusD
APPACOFM_01220	4.57e-174	-	-	-	S	-	-	-	Domain of unknown function (DUF4843)
APPACOFM_01221	0.0	-	-	-	S	-	-	-	PKD-like family
APPACOFM_01222	0.0	-	-	-	O	-	-	-	COG NOG06109 non supervised orthologous group
APPACOFM_01223	0.0	-	-	-	O	-	-	-	Domain of unknown function (DUF5118)
APPACOFM_01224	8.04e-129	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70, region 4
APPACOFM_01225	3.05e-281	-	-	-	PT	-	-	-	Sigma factor regulatory protein, FecR PupR family
APPACOFM_01226	0.0	-	-	-	P	-	-	-	Secretin and TonB N terminus short domain
APPACOFM_01227	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	SusD family
APPACOFM_01228	1.9e-211	-	-	-	-	-	-	-	-
APPACOFM_01229	0.0	-	-	-	O	-	-	-	non supervised orthologous group
APPACOFM_01230	5.5e-97	ybeY	-	-	S	-	-	-	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
APPACOFM_01231	7.17e-279	spmA	-	-	S	ko:K06373	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_01232	3.32e-242	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
APPACOFM_01233	5.48e-189	-	-	-	S	-	-	-	Phospholipase/Carboxylesterase
APPACOFM_01234	0.0	cap	-	-	S	-	-	-	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
APPACOFM_01235	6.95e-300	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
APPACOFM_01236	0.0	-	-	-	E	-	-	-	COG NOG04781 non supervised orthologous group
APPACOFM_01237	2.76e-62	-	-	-	EG	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_01238	3.78e-73	-	-	-	EG	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_01239	0.0	-	-	-	M	-	-	-	Peptidase family S41
APPACOFM_01240	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 2 family
APPACOFM_01241	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
APPACOFM_01242	0.0	-	3.2.1.20	GH31	M	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG NOG06228 non supervised orthologous group
APPACOFM_01243	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 92
APPACOFM_01244	7.34e-09	-	-	-	G	-	-	-	Glycosyl hydrolase family 92
APPACOFM_01245	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 76
APPACOFM_01246	3.33e-241	-	-	-	S	-	-	-	Domain of unknown function (DUF4361)
APPACOFM_01247	0.0	-	-	-	P	ko:K21572	-	ko00000,ko02000	Pfam:SusD
APPACOFM_01248	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_01249	0.0	-	-	-	G	-	-	-	IPT/TIG domain
APPACOFM_01250	0.0	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG COG1501 Alpha-glucosidases, family 31 of glycosyl hydrolases
APPACOFM_01251	2.97e-252	-	-	-	G	-	-	-	Glycosyl hydrolase
APPACOFM_01252	0.0	-	-	-	T	-	-	-	Response regulator receiver domain protein
APPACOFM_01253	0.0	-	3.6.4.13	-	L	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	Belongs to the DEAD box helicase family
APPACOFM_01255	9.05e-257	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
APPACOFM_01256	7.39e-225	-	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	COG COG0524 Sugar kinases, ribokinase family
APPACOFM_01257	9.89e-138	kdsD	5.3.1.13	-	M	ko:K06041	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	sugar phosphate isomerase involved in capsule formation
APPACOFM_01258	4.92e-109	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
APPACOFM_01259	9.01e-296	-	-	-	S	-	-	-	Belongs to the peptidase M16 family
APPACOFM_01260	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_01261	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_01262	4.73e-114	-	-	-	S	ko:K21572	-	ko00000,ko02000	SusD family
APPACOFM_01263	9.27e-233	-	-	-	S	ko:K21572	-	ko00000,ko02000	SusD family
APPACOFM_01264	0.0	-	3.2.1.45	GH30	G	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 30 family
APPACOFM_01265	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF5121)
APPACOFM_01266	0.0	bglB	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 3 family
APPACOFM_01267	1.71e-104	-	-	-	-	-	-	-	-
APPACOFM_01268	8.82e-154	-	-	-	C	-	-	-	WbqC-like protein
APPACOFM_01269	5.67e-231	lepB_1	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
APPACOFM_01270	0.0	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	signal peptidase i
APPACOFM_01271	3.03e-181	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the DapB family
APPACOFM_01272	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_01273	0.0	-	-	-	CO	-	-	-	COG NOG24773 non supervised orthologous group
APPACOFM_01274	3.95e-122	-	-	-	S	-	-	-	COG NOG28211 non supervised orthologous group
APPACOFM_01275	0.0	chonabc	4.2.2.20, 4.2.2.21	-	N	ko:K08961	-	ko00000,ko01000	Chondroitin sulfate ABC lyase
APPACOFM_01276	3.25e-307	-	-	-	-	-	-	-	-
APPACOFM_01277	9.81e-233	dus	-	-	H	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
APPACOFM_01278	0.0	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Divergent AAA domain protein
APPACOFM_01279	0.0	-	-	-	M	-	-	-	Domain of unknown function (DUF4955)
APPACOFM_01280	0.0	-	-	-	S	-	-	-	COG NOG38840 non supervised orthologous group
APPACOFM_01281	2.7e-258	-	-	-	S	-	-	-	Domain of unknown function (DUF5017)
APPACOFM_01282	0.0	-	-	-	GM	ko:K21572	-	ko00000,ko02000	SusD family
APPACOFM_01283	1.87e-44	-	-	-	M	-	-	-	SusD family
APPACOFM_01284	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_01285	0.0	-	-	-	P	-	-	-	COG COG3119 Arylsulfatase A and related enzymes
APPACOFM_01286	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
APPACOFM_01287	1.71e-162	-	-	-	T	-	-	-	Carbohydrate-binding family 9
APPACOFM_01288	9.03e-115	lpxA2	2.3.1.129	-	M	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	ko00000,ko00001,ko00002,ko01000,ko01005	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
APPACOFM_01289	3.95e-295	-	-	-	MU	-	-	-	Efflux transporter, outer membrane factor lipoprotein, NodT family
APPACOFM_01290	0.0	mexF	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
APPACOFM_01291	6.64e-247	mtrC	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
APPACOFM_01292	0.0	lacZ	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	COG3250 Beta-galactosidase beta-glucuronidase
APPACOFM_01293	0.0	-	-	-	S	-	-	-	COG NOG07965 non supervised orthologous group
APPACOFM_01294	4.88e-196	-	-	-	NU	-	-	-	Protein of unknown function (DUF3108)
APPACOFM_01295	2.54e-87	paaI	-	-	Q	ko:K02614	ko00360,map00360	ko00000,ko00001,ko01000	phenylacetic acid degradation protein
APPACOFM_01296	5.83e-252	-	-	-	S	-	-	-	Domain of unknown function (DUF4361)
APPACOFM_01297	0.0	-	-	-	P	-	-	-	SusD family
APPACOFM_01298	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_01299	0.0	-	-	-	G	-	-	-	IPT/TIG domain
APPACOFM_01300	1.27e-283	-	-	-	O	-	-	-	Glycosyl Hydrolase Family 88
APPACOFM_01301	0.0	aslA	-	-	P	-	-	-	COG COG3119 Arylsulfatase A and related enzymes
APPACOFM_01302	0.0	-	4.2.2.20, 4.2.2.21	-	H	ko:K08961	-	ko00000,ko01000	Chondroitin sulfate ABC lyase
APPACOFM_01303	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
APPACOFM_01304	3.16e-191	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_01305	0.0	-	2.7.11.1	-	L	ko:K08282	-	ko00000,ko01000	SNF2 family N-terminal domain
APPACOFM_01306	2.69e-12	-	2.7.11.1	-	L	ko:K08282	-	ko00000,ko01000	SNF2 family N-terminal domain
APPACOFM_01307	4.55e-266	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
APPACOFM_01308	0.0	-	-	-	H	-	-	-	GH3 auxin-responsive promoter
APPACOFM_01309	1.41e-243	pfkA	2.7.1.11, 2.7.1.90	-	F	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
APPACOFM_01310	1.45e-190	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
APPACOFM_01311	2.35e-305	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
APPACOFM_01312	7.43e-45	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
APPACOFM_01313	8.45e-147	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
APPACOFM_01314	8.61e-251	pdxB	1.1.1.290	-	H	ko:K03473	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate
APPACOFM_01315	1.85e-142	-	-	-	M	-	-	-	Protein of unknown function (DUF4254)
APPACOFM_01316	6.8e-250	-	-	GT9	M	ko:K02843	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	Glycosyltransferase family 9
APPACOFM_01317	2.56e-231	lpsA	-	-	S	-	-	-	Glycosyl transferase family 90
APPACOFM_01318	2.31e-183	-	-	-	T	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_01319	0.0	-	-	-	M	-	-	-	Glycosyltransferase like family 2
APPACOFM_01320	1.32e-248	-	-	-	M	-	-	-	Glycosyltransferase like family 2
APPACOFM_01321	1.44e-280	-	-	-	M	-	-	-	Glycosyl transferases group 1
APPACOFM_01322	8.92e-243	-	-	-	M	-	-	-	Glycosyl transferases group 1
APPACOFM_01323	4.35e-302	-	-	-	M	-	-	-	Glycosyl transferases group 1
APPACOFM_01324	6.14e-236	-	-	-	S	-	-	-	Glycosyltransferase, group 2 family protein
APPACOFM_01325	2.63e-240	-	-	-	S	-	-	-	Glycosyltransferase, group 2 family protein
APPACOFM_01326	3.28e-224	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family
APPACOFM_01327	1.37e-104	-	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	acetyltransferase
APPACOFM_01328	5.75e-286	-	-	-	F	-	-	-	ATP-grasp domain
APPACOFM_01329	3.53e-276	-	-	-	E	ko:K10907	-	ko00000,ko01000,ko01007	Aminotransferase class-V
APPACOFM_01330	2.94e-114	vioA	2.6.1.33	-	E	ko:K20429	-	ko00000,ko01000	Belongs to the DegT DnrJ EryC1 family
APPACOFM_01331	4.97e-144	vioA	2.6.1.33	-	E	ko:K20429	-	ko00000,ko01000	Belongs to the DegT DnrJ EryC1 family
APPACOFM_01332	1.4e-236	-	-	-	S	-	-	-	Core-2/I-Branching enzyme
APPACOFM_01333	4.52e-82	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.46
APPACOFM_01334	5.4e-224	-	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	Glycosyltransferase, group 2 family protein
APPACOFM_01335	2.6e-132	-	-	-	-	-	-	-	-
APPACOFM_01336	6.25e-135	-	-	-	-	-	-	-	-
APPACOFM_01337	0.0	-	-	-	-	-	-	-	-
APPACOFM_01338	0.0	-	-	-	-	-	-	-	-
APPACOFM_01339	2.25e-144	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_01340	0.0	-	-	-	S	-	-	-	P-loop ATPase and inactivated derivatives
APPACOFM_01341	0.0	msbA	-	-	V	ko:K06147,ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
APPACOFM_01342	3.03e-78	-	-	-	G	-	-	-	Domain of unknown function (DUF3473)
APPACOFM_01343	1.38e-86	-	-	-	G	-	-	-	Domain of unknown function (DUF3473)
APPACOFM_01344	0.0	-	-	-	S	-	-	-	Pfam:DUF2029
APPACOFM_01345	1.23e-276	-	-	-	S	-	-	-	Pfam:DUF2029
APPACOFM_01346	8.99e-99	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.46
APPACOFM_01347	2.05e-165	rnhA	3.1.26.4	-	C	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	double-stranded RNA RNA-DNA hybrid binding protein
APPACOFM_01348	1.31e-146	-	-	-	S	ko:K07078	-	ko00000	oxidoreductase related to nitroreductase
APPACOFM_01349	1.4e-122	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
APPACOFM_01350	0.0	speA	4.1.1.19	-	H	ko:K01585	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the biosynthesis of agmatine from arginine
APPACOFM_01351	7.1e-177	argB	2.7.2.8	-	F	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
APPACOFM_01352	5.95e-112	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
APPACOFM_01353	3.66e-103	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_01354	7.21e-133	-	-	-	S	-	-	-	Putative auto-transporter adhesin, head GIN domain
APPACOFM_01355	1.9e-164	-	-	-	S	ko:K07043	-	ko00000	Psort location Cytoplasmic, score 8.96
APPACOFM_01356	1.13e-84	-	-	-	S	-	-	-	COG NOG29451 non supervised orthologous group
APPACOFM_01357	2.55e-208	-	-	-	S	ko:K07126	-	ko00000	beta-lactamase activity
APPACOFM_01358	6.14e-105	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
APPACOFM_01359	1.24e-296	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
APPACOFM_01360	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
APPACOFM_01361	5.04e-230	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
APPACOFM_01362	2.98e-55	cvpA	-	-	S	ko:K03558	-	ko00000	Psort location CytoplasmicMembrane, score
APPACOFM_01363	9.91e-44	sufB	-	-	O	ko:K09014	-	ko00000	COG0719 ABC-type transport system involved in Fe-S cluster assembly permease component
APPACOFM_01364	5.97e-280	sufB	-	-	O	ko:K09014	-	ko00000	COG0719 ABC-type transport system involved in Fe-S cluster assembly permease component
APPACOFM_01365	2.3e-174	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	COG0396 ABC-type transport system involved in Fe-S cluster assembly ATPase component
APPACOFM_01366	0.0	sufD	-	-	O	ko:K09015	-	ko00000	COG0719 ABC-type transport system involved in Fe-S cluster assembly permease component
APPACOFM_01367	2.72e-238	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family
APPACOFM_01368	2.24e-66	-	-	-	S	-	-	-	Belongs to the UPF0145 family
APPACOFM_01369	1.66e-15	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
APPACOFM_01370	0.0	hppA	3.6.1.1	-	C	ko:K15987	ko00190,map00190	ko00000,ko00001,ko01000	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane
APPACOFM_01371	3.61e-144	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
APPACOFM_01373	0.0	-	-	-	P	-	-	-	Psort location OuterMembrane, score
APPACOFM_01374	3.64e-221	corA	-	-	P	ko:K03284	-	ko00000,ko02000	Psort location Cytoplasmic, score 8.96
APPACOFM_01375	4.45e-296	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_01376	0.0	-	-	-	CO	-	-	-	COG NOG39333 non supervised orthologous group
APPACOFM_01377	3.32e-142	gpmI	5.4.2.12	-	G	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
APPACOFM_01378	4.6e-209	gpmI	5.4.2.12	-	G	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
APPACOFM_01379	0.0	-	-	-	E	-	-	-	non supervised orthologous group
APPACOFM_01381	0.0	-	-	-	P	-	-	-	TonB-dependent Receptor Plug Domain
APPACOFM_01383	1.08e-143	-	-	-	P	-	-	-	TonB-dependent Receptor Plug Domain
APPACOFM_01384	3.43e-75	-	-	-	P	-	-	-	TonB-dependent Receptor Plug Domain
APPACOFM_01385	8.09e-283	-	-	-	P	-	-	-	TonB-dependent Receptor Plug Domain
APPACOFM_01386	6.88e-87	-	-	-	P	-	-	-	TonB-dependent Receptor Plug Domain
APPACOFM_01387	0.0	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_01389	1.17e-141	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_01390	3.98e-15	-	-	-	-	-	-	-	-
APPACOFM_01391	1.39e-31	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
APPACOFM_01392	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
APPACOFM_01393	6.07e-49	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
APPACOFM_01395	4.5e-177	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
APPACOFM_01396	0.0	-	-	-	H	-	-	-	COG NOG08812 non supervised orthologous group
APPACOFM_01397	2.83e-237	-	-	-	-	-	-	-	-
APPACOFM_01398	8.99e-310	-	-	-	NU	-	-	-	Lipid A 3-O-deacylase (PagL)
APPACOFM_01399	5.19e-103	-	-	-	-	-	-	-	-
APPACOFM_01400	1.07e-205	-	-	-	S	-	-	-	MAC/Perforin domain
APPACOFM_01401	7.11e-177	-	-	-	S	-	-	-	MAC/Perforin domain
APPACOFM_01404	2.28e-198	-	-	-	L	-	-	-	Transposase IS66 family
APPACOFM_01405	7.39e-101	-	-	-	L	-	-	-	Transposase IS66 family
APPACOFM_01406	5.14e-71	-	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 like protein
APPACOFM_01407	8.52e-83	-	-	-	L	ko:K07497	-	ko00000	transposase activity
APPACOFM_01408	3.77e-80	-	-	-	S	-	-	-	MAC/Perforin domain
APPACOFM_01409	1.11e-186	-	-	-	S	-	-	-	MAC/Perforin domain
APPACOFM_01410	6.54e-226	-	-	-	-	-	-	-	-
APPACOFM_01411	6.21e-52	-	-	-	-	-	-	-	-
APPACOFM_01412	1.45e-71	-	-	-	S	-	-	-	Domain of unknown function (DUF3244)
APPACOFM_01413	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
APPACOFM_01415	1.25e-92	-	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
APPACOFM_01416	1.18e-292	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
APPACOFM_01417	2.2e-310	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
APPACOFM_01418	4.14e-176	ftsQ	-	-	M	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Psort location Cytoplasmic, score 8.96
APPACOFM_01419	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
APPACOFM_01421	6.19e-263	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
APPACOFM_01422	7.23e-300	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
APPACOFM_01423	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
APPACOFM_01425	2.52e-301	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
APPACOFM_01426	0.0	ftsI	3.4.16.4	-	M	ko:K03587	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011,ko03036	Cell division protein FtsI penicillin-binding protein
APPACOFM_01427	1.32e-38	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_01428	1.33e-160	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
APPACOFM_01429	2.5e-109	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
APPACOFM_01430	9.58e-117	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
APPACOFM_01432	5.6e-202	-	-	-	I	-	-	-	Acyl-transferase
APPACOFM_01433	1.17e-247	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_01434	0.0	dgt	3.1.5.1	-	F	ko:K01129	ko00230,map00230	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
APPACOFM_01435	1.4e-92	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
APPACOFM_01436	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat protein
APPACOFM_01437	2.72e-122	-	-	-	S	-	-	-	COG NOG29315 non supervised orthologous group
APPACOFM_01438	1.41e-261	envC	-	-	D	-	-	-	Peptidase, M23
APPACOFM_01439	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
APPACOFM_01440	3.04e-289	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 43 family
APPACOFM_01441	2.34e-206	-	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
APPACOFM_01442	0.0	-	-	-	G	-	-	-	COG NOG29805 non supervised orthologous group
APPACOFM_01443	0.0	-	-	-	S	-	-	-	Tat pathway signal sequence domain protein
APPACOFM_01444	1.04e-45	-	-	-	-	-	-	-	-
APPACOFM_01445	0.0	-	-	-	S	-	-	-	Tat pathway signal sequence domain protein
APPACOFM_01446	1.66e-245	-	-	-	S	-	-	-	Domain of unknown function (DUF4361)
APPACOFM_01447	1.1e-54	-	-	-	P	ko:K21572	-	ko00000,ko02000	Psort location OuterMembrane, score
APPACOFM_01448	0.0	-	-	-	P	ko:K21572	-	ko00000,ko02000	Psort location OuterMembrane, score
APPACOFM_01449	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_01450	0.0	-	-	-	S	-	-	-	IPT TIG domain protein
APPACOFM_01451	0.0	-	-	-	G	-	-	-	COG NOG09951 non supervised orthologous group
APPACOFM_01452	4.51e-141	-	-	-	G	-	-	-	COG NOG09951 non supervised orthologous group
APPACOFM_01453	6.85e-313	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
APPACOFM_01454	2.41e-84	-	-	-	L	ko:K07483	-	ko00000	COG2963 Transposase and inactivated derivatives
APPACOFM_01455	1.77e-177	-	-	-	L	-	-	-	Integrase core domain
APPACOFM_01456	5.59e-135	-	-	-	G	-	-	-	COG NOG09951 non supervised orthologous group
APPACOFM_01457	0.0	-	-	-	S	-	-	-	IPT TIG domain protein
APPACOFM_01458	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_01459	0.0	-	-	-	P	ko:K21572	-	ko00000,ko02000	Psort location OuterMembrane, score
APPACOFM_01460	1.5e-254	-	-	-	S	-	-	-	Domain of unknown function (DUF4361)
APPACOFM_01461	0.0	-	-	-	P	-	-	-	COG COG3119 Arylsulfatase A and related enzymes
APPACOFM_01462	0.0	-	3.1.6.1	-	P	ko:K01130	ko00140,ko00600,map00140,map00600	ko00000,ko00001,ko01000	COG COG3119 Arylsulfatase A and related enzymes
APPACOFM_01463	0.0	-	3.1.6.1	-	P	ko:K01130	ko00140,ko00600,map00140,map00600	ko00000,ko00001,ko01000	COG COG3119 Arylsulfatase A and related enzymes
APPACOFM_01464	0.0	-	-	-	P	-	-	-	Sulfatase
APPACOFM_01465	0.0	-	-	-	S	ko:K06921	-	ko00000	ATPase (AAA superfamily)
APPACOFM_01466	8.81e-129	-	-	-	G	-	-	-	COG NOG09951 non supervised orthologous group
APPACOFM_01467	0.0	-	-	-	S	-	-	-	IPT TIG domain protein
APPACOFM_01468	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_01469	0.0	-	-	-	P	ko:K21572	-	ko00000,ko02000	Psort location OuterMembrane, score
APPACOFM_01470	1.79e-244	-	-	-	S	-	-	-	Domain of unknown function (DUF4361)
APPACOFM_01471	1.62e-179	-	-	-	S	-	-	-	VTC domain
APPACOFM_01472	3.15e-154	-	-	-	S	-	-	-	Domain of unknown function (DUF4956)
APPACOFM_01473	3.57e-184	-	-	-	S	-	-	-	Protein of unknown function (DUF2490)
APPACOFM_01474	0.0	-	-	-	M	-	-	-	CotH kinase protein
APPACOFM_01475	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase
APPACOFM_01477	6.98e-130	-	-	-	G	-	-	-	COG NOG09951 non supervised orthologous group
APPACOFM_01478	0.0	-	-	-	S	-	-	-	IPT/TIG domain
APPACOFM_01479	0.0	-	-	-	P	-	-	-	TonB dependent receptor
APPACOFM_01480	0.0	-	-	-	P	ko:K21572	-	ko00000,ko02000	SusD family
APPACOFM_01481	1.23e-55	-	-	-	P	ko:K21572	-	ko00000,ko02000	SusD family
APPACOFM_01482	1.64e-262	-	-	-	S	-	-	-	Domain of unknown function (DUF4361)
APPACOFM_01483	0.0	-	-	-	S	-	-	-	TonB-dependent Receptor Plug Domain
APPACOFM_01484	1.92e-133	-	-	-	S	-	-	-	Tetratricopeptide repeat
APPACOFM_01485	6.46e-97	-	-	-	-	-	-	-	-
APPACOFM_01486	1.41e-109	-	-	-	S	-	-	-	Protein of unknown function (DUF3828)
APPACOFM_01487	0.0	-	-	-	G	-	-	-	COG NOG09951 non supervised orthologous group
APPACOFM_01488	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 2 family
APPACOFM_01489	0.0	-	-	-	S	-	-	-	COG NOG06097 non supervised orthologous group
APPACOFM_01490	2.58e-275	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 43 family
APPACOFM_01491	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 43 family
APPACOFM_01492	3.48e-128	-	-	-	K	-	-	-	RNA polymerase sigma-70 factor, ECF subfamily
APPACOFM_01493	5.24e-08	-	-	-	PT	-	-	-	Sigma factor regulatory protein, FecR PupR family
APPACOFM_01494	6.03e-265	-	-	-	PT	-	-	-	Sigma factor regulatory protein, FecR PupR family
APPACOFM_01495	0.0	-	-	-	H	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_01496	0.0	-	-	-	P	ko:K21572	-	ko00000,ko02000	SusD family
APPACOFM_01497	4.81e-308	-	-	-	G	-	-	-	Glycosyl hydrolase family 76
APPACOFM_01498	2.85e-292	-	-	-	S	-	-	-	Domain of unknown function (DUF4972)
APPACOFM_01499	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4972)
APPACOFM_01500	0.0	-	-	-	M	-	-	-	Glycosyl hydrolase family 76
APPACOFM_01501	0.0	-	-	-	S	-	-	-	COG NOG26804 non supervised orthologous group
APPACOFM_01502	0.0	-	-	-	G	-	-	-	COG NOG09951 non supervised orthologous group
APPACOFM_01503	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 92
APPACOFM_01504	0.0	-	-	-	S	ko:K09704	-	ko00000	Conserved protein
APPACOFM_01505	5.07e-285	mro_1	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Converts alpha-aldose to the beta-anomer
APPACOFM_01506	3.34e-312	-	-	-	G	-	-	-	Glycosyl hydrolase family 92
APPACOFM_01507	3.22e-155	-	-	-	G	-	-	-	Glycosyl hydrolase family 92
APPACOFM_01508	0.0	-	-	-	S	-	-	-	protein conserved in bacteria
APPACOFM_01509	1.52e-286	mro_1	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Converts alpha-aldose to the beta-anomer
APPACOFM_01510	0.0	-	-	-	M	-	-	-	O-antigen ligase like membrane protein
APPACOFM_01511	4.34e-167	-	-	-	-	-	-	-	-
APPACOFM_01512	1.19e-168	-	-	-	-	-	-	-	-
APPACOFM_01514	1.65e-225	-	-	-	S	ko:K09924	-	ko00000	COG NOG19128 non supervised orthologous group
APPACOFM_01516	5.66e-169	-	-	-	-	-	-	-	-
APPACOFM_01517	1.57e-55	-	-	-	-	-	-	-	-
APPACOFM_01518	1.05e-158	-	-	-	-	-	-	-	-
APPACOFM_01519	0.0	-	-	-	E	-	-	-	non supervised orthologous group
APPACOFM_01520	3.84e-27	-	-	-	-	-	-	-	-
APPACOFM_01522	0.0	-	-	-	M	-	-	-	O-antigen ligase like membrane protein
APPACOFM_01523	0.0	-	-	-	G	-	-	-	Domain of unknown function (DUF5127)
APPACOFM_01524	1.14e-142	-	-	-	-	-	-	-	-
APPACOFM_01526	5.2e-294	-	-	-	S	ko:K07133	-	ko00000	AAA domain
APPACOFM_01527	1.45e-257	argE	3.5.1.16	-	E	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related
APPACOFM_01530	5.65e-99	-	-	-	S	-	-	-	Concanavalin A-like lectin/glucanases superfamily
APPACOFM_01531	2.93e-121	-	-	-	G	-	-	-	Putative glycoside hydrolase Family 18, chitinase_18
APPACOFM_01532	1.07e-202	-	-	-	S	-	-	-	Susd and RagB outer membrane lipoprotein
APPACOFM_01533	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_01534	2.1e-207	-	-	-	PT	-	-	-	Sigma factor regulatory protein, FecR PupR family
APPACOFM_01535	4.61e-122	rpoE3	-	-	K	ko:K03088	-	ko00000,ko03021	RNA polymerase sigma-70 factor
APPACOFM_01536	4.86e-07	-	-	-	L	-	-	-	COG COG3385 FOG Transposase and inactivated derivatives
APPACOFM_01537	0.0	fadD	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
APPACOFM_01538	0.0	-	-	-	S	-	-	-	Peptidase M16 inactive domain
APPACOFM_01539	5.43e-228	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
APPACOFM_01540	2.39e-18	-	-	-	-	-	-	-	-
APPACOFM_01541	3.27e-256	-	-	-	P	-	-	-	phosphate-selective porin
APPACOFM_01542	5.46e-108	cyaA	4.6.1.1	-	S	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.96
APPACOFM_01543	2.79e-293	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_01544	1.98e-65	-	-	-	K	-	-	-	sequence-specific DNA binding
APPACOFM_01545	9.83e-244	-	2.7.11.1	-	S	ko:K07154	-	ko00000,ko01000,ko01001,ko02048	Psort location Cytoplasmic, score 8.96
APPACOFM_01546	2.85e-235	-	-	-	F	ko:K01173	ko04210,map04210	ko00000,ko00001,ko03029	DNA/RNA non-specific endonuclease
APPACOFM_01547	1.33e-256	-	-	-	S	-	-	-	Endonuclease Exonuclease phosphatase family
APPACOFM_01548	0.0	-	-	-	P	-	-	-	Psort location OuterMembrane, score
APPACOFM_01549	5.06e-196	-	-	-	S	-	-	-	PFAM nucleic acid binding, OB-fold, tRNA
APPACOFM_01550	4.04e-138	-	-	-	S	-	-	-	PFAM nucleic acid binding, OB-fold, tRNA
APPACOFM_01551	1.69e-128	-	-	-	F	ko:K01173	ko04210,map04210	ko00000,ko00001,ko03029	COG1864 DNA RNA endonuclease G, NUC1
APPACOFM_01552	1.6e-98	-	-	-	-	-	-	-	-
APPACOFM_01554	0.0	-	-	-	M	-	-	-	TonB-dependent receptor
APPACOFM_01555	0.0	-	-	-	S	-	-	-	protein conserved in bacteria
APPACOFM_01556	1.89e-114	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	glycosyl hydrolase, family 3
APPACOFM_01557	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	glycosyl hydrolase, family 3
APPACOFM_01558	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	COG NOG26302 non supervised orthologous group
APPACOFM_01560	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_01561	4.96e-163	-	-	-	S	-	-	-	Tetratricopeptide repeats
APPACOFM_01562	1.81e-215	-	-	-	S	-	-	-	Tetratricopeptide repeats
APPACOFM_01566	5.93e-155	-	-	-	-	-	-	-	-
APPACOFM_01569	5.17e-219	-	-	-	G	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_01571	3.73e-220	-	-	-	M	-	-	-	peptidase S41
APPACOFM_01572	8.2e-211	-	-	-	S	-	-	-	COG NOG19130 non supervised orthologous group
APPACOFM_01573	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	COG0188 Type IIA topoisomerase (DNA gyrase topo II topoisomerase IV) A subunit
APPACOFM_01574	0.0	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
APPACOFM_01575	1.96e-45	-	-	-	-	-	-	-	-
APPACOFM_01576	0.0	-	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
APPACOFM_01577	3.12e-174	-	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
APPACOFM_01578	0.0	-	-	-	S	-	-	-	Putative oxidoreductase C terminal domain
APPACOFM_01579	3.88e-240	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
APPACOFM_01580	4.7e-193	-	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
APPACOFM_01581	4.2e-284	-	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
APPACOFM_01582	4.65e-312	-	-	-	G	ko:K02429	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_01583	0.0	-	3.2.1.50	-	G	ko:K01205	ko00531,ko01100,ko04142,map00531,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko04147	Alpha-N-acetylglucosaminidase
APPACOFM_01584	3.02e-301	-	-	-	C	-	-	-	Domain of unknown function (DUF4855)
APPACOFM_01585	6.98e-21	-	-	-	E	-	-	-	COG NOG09493 non supervised orthologous group
APPACOFM_01586	0.0	-	-	-	G	-	-	-	Phosphodiester glycosidase
APPACOFM_01587	0.0	-	-	-	G	-	-	-	hydrolase activity, acting on glycosyl bonds
APPACOFM_01588	0.0	-	-	-	-	-	-	-	-
APPACOFM_01589	0.0	-	3.1.1.53	-	G	ko:K05970	-	ko00000,ko01000	COG NOG04984 non supervised orthologous group
APPACOFM_01590	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycosyl hydrolase family 20, catalytic domain
APPACOFM_01591	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 2 family
APPACOFM_01592	9.28e-54	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 2 family
APPACOFM_01593	2.17e-212	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
APPACOFM_01594	2.56e-248	-	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	SIS domain
APPACOFM_01595	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF5018)
APPACOFM_01596	0.0	-	-	-	F	ko:K21572	-	ko00000,ko02000	SusD family
APPACOFM_01597	0.0	-	-	-	H	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_01598	3.04e-312	ce	5.1.3.8	-	G	ko:K01787	ko00520,map00520	ko00000,ko00001,ko01000	COG COG2942 N-acyl-D-glucosamine 2-epimerase
APPACOFM_01599	1.22e-183	araE	-	-	P	ko:K08138,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
APPACOFM_01601	1.43e-278	-	-	-	S	-	-	-	Domain of unknown function (DUF5109)
APPACOFM_01602	1.41e-184	-	-	-	Q	-	-	-	Dienelactone hydrolase
APPACOFM_01603	2.74e-280	-	-	-	K	ko:K02529	-	ko00000,ko03000	transcriptional regulator (AraC family)
APPACOFM_01604	4.47e-103	-	-	-	L	-	-	-	DNA-binding protein
APPACOFM_01605	0.0	glyQS	6.1.1.14	-	J	ko:K01880	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of glycine to tRNA(Gly)
APPACOFM_01606	8.89e-143	-	5.2.1.8	-	M	ko:K01802,ko:K03773	-	ko00000,ko01000,ko03110	FkbP-type peptidyl-prolyl cis-trans
APPACOFM_01607	5.15e-247	-	-	-	K	ko:K02529	-	ko00000,ko03000	Psort location Cytoplasmic, score 9.97
APPACOFM_01608	5.21e-226	fdh	1.1.1.122	-	C	ko:K00064	ko00051,ko00053,ko01100,ko01110,ko01120,map00051,map00053,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Oxidoreductase, aldo keto reductase family protein
APPACOFM_01609	1.88e-222	-	-	-	S	ko:K07045	-	ko00000	Psort location Cytoplasmic, score 8.96
APPACOFM_01610	2.73e-303	fucP	-	-	G	ko:K02429	-	ko00000,ko02000	L-fucose H symporter permease
APPACOFM_01611	1.59e-241	yjmD_1	-	-	E	-	-	-	Psort location Cytoplasmic, score 9.97
APPACOFM_01612	6.43e-202	-	-	-	G	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_01613	1.33e-172	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_01614	5.7e-68	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_01615	3.63e-232	-	-	-	EGP	ko:K08218	ko01501,map01501	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_01616	1.41e-54	-	-	-	EGP	ko:K08218	ko01501,map01501	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_01617	5.68e-215	lytB	-	-	D	ko:K06381	-	ko00000	SpoIID LytB domain protein
APPACOFM_01618	0.0	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
APPACOFM_01619	0.0	-	-	-	E	-	-	-	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
APPACOFM_01620	7.47e-298	-	-	-	S	-	-	-	Lamin Tail Domain
APPACOFM_01621	3.05e-54	-	-	-	S	-	-	-	Domain of unknown function (DUF4857)
APPACOFM_01622	7.71e-174	-	-	-	S	-	-	-	Domain of unknown function (DUF4857)
APPACOFM_01623	6.87e-153	-	-	-	-	-	-	-	-
APPACOFM_01624	3.1e-215	-	-	-	V	ko:K01990,ko:K19340	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1131 ABC-type multidrug transport system ATPase component
APPACOFM_01625	1.61e-132	-	-	-	S	ko:K09939	-	ko00000	Putative PepSY_TM-like
APPACOFM_01626	3.16e-122	-	-	-	-	-	-	-	-
APPACOFM_01627	0.0	-	-	-	S	-	-	-	Fibrobacter succinogenes major domain (Fib_succ_major)
APPACOFM_01628	0.0	-	-	-	-	-	-	-	-
APPACOFM_01629	6.99e-307	-	-	-	S	-	-	-	Protein of unknown function (DUF4876)
APPACOFM_01630	0.0	-	-	-	P	-	-	-	COG NOG11715 non supervised orthologous group
APPACOFM_01631	3.45e-239	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
APPACOFM_01632	0.0	-	-	-	H	-	-	-	COG NOG08812 non supervised orthologous group
APPACOFM_01633	0.0	-	-	-	PT	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_01634	1.1e-166	hypB	-	-	H	ko:K22132	-	ko00000,ko03016	involved in molybdopterin and thiamine biosynthesis family 1
APPACOFM_01635	2.4e-151	lolD	-	-	V	ko:K09810	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner
APPACOFM_01636	7.56e-214	comEA	-	-	L	-	-	-	COG COG1555 DNA uptake protein and related DNA-binding proteins
APPACOFM_01637	2.44e-287	-	-	-	P	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
APPACOFM_01638	1.09e-95	fjo27	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.46
APPACOFM_01639	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
APPACOFM_01640	0.0	-	-	-	T	-	-	-	histidine kinase DNA gyrase B
APPACOFM_01641	3.72e-203	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.96
APPACOFM_01642	5.55e-168	dacA	-	-	S	-	-	-	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
APPACOFM_01643	0.0	tldD1	-	-	S	ko:K03568	-	ko00000,ko01002	and their inactivated homologs
APPACOFM_01644	3.12e-315	tldD3	-	-	S	ko:K03592	-	ko00000,ko01002	Psort location Cytoplasmic, score 9.26
APPACOFM_01645	8.25e-125	-	-	-	S	ko:K03744	-	ko00000	LemA family
APPACOFM_01646	1.19e-217	-	-	-	S	-	-	-	Protein of unknown function (DUF3137)
APPACOFM_01647	4.53e-196	-	-	-	S	-	-	-	Protein of unknown function (DUF1266)
APPACOFM_01648	1.27e-129	-	-	-	-	-	-	-	-
APPACOFM_01649	0.0	-	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 35 family
APPACOFM_01650	8.5e-243	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 43 family
APPACOFM_01651	0.0	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
APPACOFM_01652	0.0	-	-	-	G	-	-	-	Carbohydrate binding domain protein
APPACOFM_01653	0.0	-	3.2.1.177	GH31	G	ko:K01811	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 31 family
APPACOFM_01654	0.0	-	-	-	KT	-	-	-	Y_Y_Y domain
APPACOFM_01655	0.0	-	-	-	G	-	-	-	COG NOG26813 non supervised orthologous group
APPACOFM_01656	1.05e-173	-	-	-	G	-	-	-	F5/8 type C domain
APPACOFM_01657	1.85e-165	-	-	-	G	-	-	-	F5/8 type C domain
APPACOFM_01658	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
APPACOFM_01659	7.71e-82	-	5.1.3.32	-	G	ko:K03534	-	ko00000,ko01000	Psort location Cytoplasmic, score 8.96
APPACOFM_01660	3.43e-156	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
APPACOFM_01661	0.0	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
APPACOFM_01662	0.0	-	-	-	G	-	-	-	Glycosyl-hydrolase 97 C-terminal, oligomerisation
APPACOFM_01663	7.82e-203	-	-	-	M	-	-	-	Domain of unknown function (DUF4488)
APPACOFM_01664	0.0	-	-	-	S	ko:K09955	-	ko00000	protein conserved in bacteria
APPACOFM_01665	1.38e-253	-	-	-	G	-	-	-	hydrolase, family 43
APPACOFM_01667	2.5e-238	-	-	-	S	-	-	-	Domain of unknown function (DUF4419)
APPACOFM_01668	0.0	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2264)
APPACOFM_01669	0.0	-	-	-	N	-	-	-	BNR repeat-containing family member
APPACOFM_01670	0.0	-	-	-	T	-	-	-	adenylate cyclase carring two-component hybrid sensor and regulator domains
APPACOFM_01673	2.22e-117	-	-	-	S	-	-	-	amine dehydrogenase activity
APPACOFM_01674	4.77e-149	-	-	-	S	-	-	-	amine dehydrogenase activity
APPACOFM_01675	0.0	-	-	-	H	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_01676	0.0	-	-	-	P	ko:K21572	-	ko00000,ko02000	Psort location OuterMembrane, score
APPACOFM_01677	7.62e-216	-	-	-	S	-	-	-	Domain of unknown function (DUF4361)
APPACOFM_01678	0.0	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
APPACOFM_01679	2.17e-268	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
APPACOFM_01680	0.0	-	-	-	S	-	-	-	COG NOG19133 non supervised orthologous group
APPACOFM_01681	1.48e-295	-	-	-	E	-	-	-	Glycosyl Hydrolase Family 88
APPACOFM_01682	1e-249	-	-	-	S	-	-	-	acetyltransferase involved in intracellular survival and related
APPACOFM_01683	2.1e-53	-	-	-	S	ko:K01163	-	ko00000	Conserved protein
APPACOFM_01684	3.13e-154	-	-	-	S	ko:K01163	-	ko00000	Conserved protein
APPACOFM_01685	5.97e-147	lrgB	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_01686	1.93e-70	lrgA	-	-	S	ko:K06518	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score
APPACOFM_01687	6.41e-237	pta	2.3.1.8	-	C	ko:K00625,ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
APPACOFM_01688	5.44e-60	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
APPACOFM_01689	6.78e-210	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
APPACOFM_01690	6.26e-150	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 9.46
APPACOFM_01691	4.86e-133	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 9.46
APPACOFM_01692	1.02e-163	radC	-	-	E	ko:K03630	-	ko00000	Belongs to the UPF0758 family
APPACOFM_01693	6.82e-66	yitW	-	-	S	-	-	-	FeS assembly SUF system protein
APPACOFM_01694	5.5e-193	lpxH	3.6.1.54	-	S	ko:K03269	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Psort location Cytoplasmic, score
APPACOFM_01695	0.0	-	3.2.1.1, 3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	M	ko:K01176,ko:K01208	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Alpha-amylase domain
APPACOFM_01696	0.0	-	-	-	S	ko:K21571	-	ko00000	Domain of unknown function (DUF5115)
APPACOFM_01697	4.92e-288	-	-	-	S	ko:K21571	-	ko00000	Outer membrane protein SusF_SusE
APPACOFM_01698	0.0	susD	-	-	M	ko:K21572	-	ko00000,ko02000	SusD family
APPACOFM_01699	0.0	-	-	-	HP	ko:K21573	-	ko00000,ko02000	TonB dependent receptor
APPACOFM_01700	0.0	susB	3.2.1.20, 3.2.1.3	GH31,GH97	G	ko:K01187,ko:K21574	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG NOG06228 non supervised orthologous group
APPACOFM_01701	1.38e-55	susB	3.2.1.20, 3.2.1.3	GH31,GH97	G	ko:K01187,ko:K21574	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG NOG06228 non supervised orthologous group
APPACOFM_01702	0.0	-	3.2.1.135	GH13	G	ko:K21575	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 13 family
APPACOFM_01703	0.0	-	-	-	S	ko:K21557	-	ko00000,ko03000	Psort location Cytoplasmic, score 8.96
APPACOFM_01704	2.41e-84	-	-	-	L	ko:K07483	-	ko00000	COG2963 Transposase and inactivated derivatives
APPACOFM_01705	1.77e-177	-	-	-	L	-	-	-	Integrase core domain
APPACOFM_01706	5.94e-287	-	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Belongs to the alkaline phosphatase family
APPACOFM_01707	1.89e-26	-	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Belongs to the alkaline phosphatase family
APPACOFM_01708	2.28e-132	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
APPACOFM_01709	8.16e-29	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
APPACOFM_01710	8.65e-144	spk1	2.7.11.1, 6.3.2.4	-	S	ko:K01921,ko:K08884,ko:K12132	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01001,ko01011	PASTA domain protein
APPACOFM_01711	1.51e-64	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
APPACOFM_01712	1.08e-179	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
APPACOFM_01713	8.95e-225	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
APPACOFM_01714	2.22e-277	-	-	-	I	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_01715	2.49e-167	-	-	-	S	-	-	-	COG NOG31798 non supervised orthologous group
APPACOFM_01716	8.64e-84	glpE	-	-	P	-	-	-	Rhodanese-like protein
APPACOFM_01717	1.4e-234	argF	2.1.3.11, 2.1.3.9	-	E	ko:K09065,ko:K13043	ko00220,ko01100,ko01230,map00220,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
APPACOFM_01718	4.49e-297	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
APPACOFM_01719	1.76e-99	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
APPACOFM_01720	1.57e-121	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
APPACOFM_01721	1.97e-276	-	-	-	E	-	-	-	DegT/DnrJ/EryC1/StrS aminotransferase family
APPACOFM_01722	1.24e-47	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_01723	4.54e-205	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
APPACOFM_01724	4.45e-89	ompH	-	-	M	ko:K06142	-	ko00000	membrane
APPACOFM_01725	3.54e-105	ompH	-	-	M	ko:K06142	-	ko00000	membrane
APPACOFM_01726	0.0	yaeT	-	-	M	ko:K07277	-	ko00000,ko02000,ko03029	Outer membrane protein assembly complex, YaeT protein
APPACOFM_01727	4.49e-178	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
APPACOFM_01728	0.0	-	-	-	G	-	-	-	COG NOG27066 non supervised orthologous group
APPACOFM_01729	3.38e-245	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
APPACOFM_01730	7.77e-196	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
APPACOFM_01731	2.48e-111	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
APPACOFM_01732	2.15e-151	pyrE	2.4.2.10, 4.1.1.23	-	F	ko:K00762,ko:K13421	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
APPACOFM_01733	1.52e-89	-	-	-	S	-	-	-	Polyketide cyclase / dehydrase and lipid transport
APPACOFM_01734	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Psort location Cytoplasmic, score
APPACOFM_01737	1.83e-300	-	-	-	E	-	-	-	FAD dependent oxidoreductase
APPACOFM_01738	9.13e-37	-	-	-	-	-	-	-	-
APPACOFM_01739	2.84e-18	-	-	-	-	-	-	-	-
APPACOFM_01741	4.22e-60	-	-	-	-	-	-	-	-
APPACOFM_01743	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
APPACOFM_01744	0.0	-	-	-	P	ko:K14445	-	ko00000,ko02000	Citrate transporter
APPACOFM_01745	0.0	-	-	-	S	-	-	-	Fibrobacter succinogenes major domain (Fib_succ_major)
APPACOFM_01746	2.93e-53	-	-	-	S	-	-	-	amine dehydrogenase activity
APPACOFM_01747	0.0	-	-	-	S	-	-	-	amine dehydrogenase activity
APPACOFM_01749	0.0	-	-	-	N	-	-	-	domain, Protein
APPACOFM_01750	1.4e-194	-	-	-	S	-	-	-	COG NOG19137 non supervised orthologous group
APPACOFM_01751	6.2e-264	-	-	-	S	-	-	-	non supervised orthologous group
APPACOFM_01753	9.49e-89	-	-	-	-	-	-	-	-
APPACOFM_01754	5.79e-39	-	-	-	-	-	-	-	-
APPACOFM_01755	7.99e-120	-	-	-	K	ko:K03088	-	ko00000,ko03021	RNA polymerase sigma-70 factor, Bacteroides expansion family 1
APPACOFM_01756	6.57e-226	-	-	-	PT	-	-	-	Sigma factor regulatory protein, FecR PupR family
APPACOFM_01757	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_01758	0.0	-	-	-	S	-	-	-	non supervised orthologous group
APPACOFM_01759	1.39e-286	-	-	-	G	-	-	-	Putative glycoside hydrolase Family 18, chitinase_18
APPACOFM_01760	3.89e-285	-	-	-	NU	-	-	-	bacterial-type flagellum-dependent cell motility
APPACOFM_01761	0.0	acsA	6.2.1.1, 6.2.1.32	-	I	ko:K01895,ko:K08295	ko00010,ko00620,ko00627,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00627,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	Psort location Cytoplasmic, score
APPACOFM_01762	2.57e-127	-	-	-	K	-	-	-	Cupin domain protein
APPACOFM_01763	1.87e-172	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
APPACOFM_01764	4.1e-273	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
APPACOFM_01765	9.86e-237	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
APPACOFM_01766	6.67e-287	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate synthase
APPACOFM_01767	1.04e-139	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
APPACOFM_01768	1.89e-100	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
APPACOFM_01769	3.5e-11	-	-	-	-	-	-	-	-
APPACOFM_01770	0.0	rhaB	2.7.1.5, 2.7.1.51	-	G	ko:K00848,ko:K00879	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
APPACOFM_01771	1.46e-13	rhaA	5.3.1.14	-	G	ko:K01813	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.96
APPACOFM_01772	1.57e-275	rhaA	5.3.1.14	-	G	ko:K01813	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.96
APPACOFM_01773	9.91e-241	rhaT	-	-	EG	ko:K02856	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_01774	3.57e-78	rhaD	4.1.2.19	-	G	ko:K01629	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	COG COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
APPACOFM_01775	3.2e-81	rhaD	4.1.2.19	-	G	ko:K01629	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	COG COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
APPACOFM_01776	2.78e-272	fucO	1.1.1.77	-	C	ko:K00048	ko00630,ko00640,ko01120,map00630,map00640,map01120	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
APPACOFM_01777	6.27e-217	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 9.26
APPACOFM_01778	9.63e-85	-	-	-	S	-	-	-	Domain of unknown function (DUF4890)
APPACOFM_01780	3.21e-136	qacR	-	-	K	-	-	-	transcriptional regulator, TetR family
APPACOFM_01781	3.5e-168	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	with different specificities (related to short-chain alcohol
APPACOFM_01782	2.15e-161	rluC	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	ribosomal pseudouridine synthase C, large subunit
APPACOFM_01783	0.0	-	-	-	G	-	-	-	Alpha-1,2-mannosidase
APPACOFM_01784	0.0	-	3.2.1.24	GH38	G	ko:K01191	ko00511,map00511	ko00000,ko00001,ko01000,ko04131	Glycosyl hydrolase family 38 C-terminal domain protein
APPACOFM_01786	5.5e-169	-	-	-	M	-	-	-	pathogenesis
APPACOFM_01787	3.58e-183	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
APPACOFM_01789	2.4e-192	-	3.1.3.6, 3.1.4.16	-	M	ko:K01119,ko:K02450,ko:K14197	ko00230,ko00240,ko05150,map00230,map00240,map05150	ko00000,ko00001,ko00002,ko01000,ko02044	LysM domain
APPACOFM_01790	0.0	-	-	-	-	-	-	-	-
APPACOFM_01791	2.19e-298	-	3.2.1.197	-	G	ko:K21065	-	ko00000,ko01000	beta-1,4-mannooligosaccharide phosphorylase
APPACOFM_01792	0.0	-	-	-	S	ko:K09704	-	ko00000	Conserved protein
APPACOFM_01793	2.68e-301	-	-	-	G	-	-	-	Glycosyl hydrolase family 76
APPACOFM_01794	1.78e-240	-	-	-	S	-	-	-	Endonuclease Exonuclease phosphatase family
APPACOFM_01795	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 92
APPACOFM_01796	0.0	-	-	-	T	-	-	-	Response regulator receiver domain protein
APPACOFM_01797	0.0	-	-	-	T	-	-	-	Response regulator receiver domain protein
APPACOFM_01798	3.2e-297	-	-	-	S	-	-	-	IPT/TIG domain
APPACOFM_01799	0.0	-	-	-	P	-	-	-	TonB dependent receptor
APPACOFM_01800	0.0	-	-	-	P	ko:K21572	-	ko00000,ko02000	non supervised orthologous group
APPACOFM_01801	7.74e-179	-	-	-	S	-	-	-	Domain of unknown function (DUF4361)
APPACOFM_01802	1.18e-314	-	-	-	S	-	-	-	Concanavalin A-like lectin/glucanases superfamily
APPACOFM_01803	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 76
APPACOFM_01804	4.42e-33	-	-	-	-	-	-	-	-
APPACOFM_01806	0.0	-	-	-	P	-	-	-	COG COG3119 Arylsulfatase A and related enzymes
APPACOFM_01807	0.0	-	-	-	G	-	-	-	Raffinose synthase or seed imbibition protein Sip1
APPACOFM_01808	0.0	-	-	-	G	-	-	-	Alpha-L-fucosidase
APPACOFM_01809	0.0	-	-	-	P	-	-	-	COG COG3119 Arylsulfatase A and related enzymes
APPACOFM_01810	0.0	-	-	-	T	-	-	-	cheY-homologous receiver domain
APPACOFM_01811	0.0	-	-	-	T	ko:K07713	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains
APPACOFM_01812	1.35e-201	-	5.2.1.8	-	M	ko:K01802,ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
APPACOFM_01813	9.08e-299	-	-	-	S	ko:K07263	-	ko00000,ko01000,ko01002	Peptidase M16 inactive domain protein
APPACOFM_01814	0.0	norM	-	-	V	ko:K03327	-	ko00000,ko02000	MATE efflux family protein
APPACOFM_01815	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
APPACOFM_01816	0.0	-	-	-	S	-	-	-	Psort location OuterMembrane, score 9.49
APPACOFM_01817	2.23e-127	-	-	-	M	-	-	-	Outer membrane protein, OMP85 family
APPACOFM_01818	0.0	-	-	-	M	-	-	-	Outer membrane protein, OMP85 family
APPACOFM_01819	8.65e-226	-	-	-	JM	-	-	-	COG NOG09722 non supervised orthologous group
APPACOFM_01820	0.0	-	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
APPACOFM_01821	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
APPACOFM_01822	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	bifunctional purine biosynthesis protein PurH
APPACOFM_01823	5.31e-241	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein, MreB Mrl family
APPACOFM_01824	2.6e-195	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
APPACOFM_01825	9.96e-109	mreD	-	-	S	-	-	-	rod shape-determining protein MreD
APPACOFM_01826	0.0	mrdA	3.4.16.4	-	M	ko:K05515	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011	penicillin-binding protein 2
APPACOFM_01827	3.42e-116	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
APPACOFM_01828	7.56e-205	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
APPACOFM_01829	1.09e-274	yaaT	-	-	S	-	-	-	PSP1 C-terminal domain protein
APPACOFM_01830	2.56e-272	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	COG2812 DNA polymerase III gamma tau subunits
APPACOFM_01831	5.05e-232	metF	1.5.1.20	-	C	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
APPACOFM_01832	1.1e-115	-	-	-	-	-	-	-	-
APPACOFM_01833	4.2e-117	-	1.16.3.1	-	S	ko:K03594	ko00860,map00860	ko00000,ko00001,ko01000	Ferritin-like domain
APPACOFM_01835	1.77e-177	-	-	-	L	-	-	-	Integrase core domain
APPACOFM_01836	2.41e-84	-	-	-	L	ko:K07483	-	ko00000	COG2963 Transposase and inactivated derivatives
APPACOFM_01837	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
APPACOFM_01840	8.45e-140	-	-	-	M	-	-	-	Chaperone of endosialidase
APPACOFM_01841	3.16e-155	-	-	-	H	-	-	-	Methyltransferase domain
APPACOFM_01845	2.85e-128	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_01846	3.5e-40	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
APPACOFM_01847	7.66e-252	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
APPACOFM_01848	1.11e-207	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
APPACOFM_01849	6.37e-314	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
APPACOFM_01850	6.08e-177	lptB	-	-	S	ko:K06861	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Psort location Cytoplasmic, score 9.12
APPACOFM_01851	5.15e-165	mlaE	-	-	Q	ko:K02066	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_01852	8.69e-182	metN	-	-	Q	ko:K02065	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
APPACOFM_01853	1.2e-49	-	-	-	S	-	-	-	COG COG0724 RNA-binding proteins (RRM domain)
APPACOFM_01854	1.5e-310	tig	-	-	O	ko:K03545	-	ko00000	peptidyl-prolyl cis-trans isomerase (trigger factor)
APPACOFM_01855	7.17e-154	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
APPACOFM_01856	2.92e-296	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
APPACOFM_01857	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
APPACOFM_01858	3.79e-194	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
APPACOFM_01859	7.66e-139	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
APPACOFM_01860	3.41e-31	-	5.2.1.8	-	M	ko:K03771	-	ko00000,ko01000,ko03110	COG COG0760 Parvulin-like peptidyl-prolyl isomerase
APPACOFM_01861	0.0	-	5.2.1.8	-	M	ko:K03771	-	ko00000,ko01000,ko03110	COG COG0760 Parvulin-like peptidyl-prolyl isomerase
APPACOFM_01862	9.89e-201	-	-	-	O	-	-	-	COG NOG23400 non supervised orthologous group
APPACOFM_01863	0.0	surA	5.2.1.8	-	M	ko:K03771	-	ko00000,ko01000,ko03110	peptidylprolyl isomerase
APPACOFM_01864	0.0	lptD	-	-	M	-	-	-	COG NOG06415 non supervised orthologous group
APPACOFM_01865	1.34e-66	-	-	-	S	-	-	-	COG NOG23401 non supervised orthologous group
APPACOFM_01866	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
APPACOFM_01867	8.17e-286	-	-	-	M	-	-	-	Psort location OuterMembrane, score
APPACOFM_01868	0.0	-	-	-	T	-	-	-	COG NOG26059 non supervised orthologous group
APPACOFM_01869	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_01870	0.0	-	-	-	P	ko:K21572	-	ko00000,ko02000	SusD family
APPACOFM_01871	5.25e-166	-	-	-	S	-	-	-	Protein of unknown function (DUF3823)
APPACOFM_01872	0.0	-	-	-	K	-	-	-	DNA-templated transcription, initiation
APPACOFM_01873	0.0	-	-	-	G	-	-	-	cog cog3537
APPACOFM_01874	6.68e-172	-	-	-	G	-	-	-	cog cog3537
APPACOFM_01875	0.0	-	-	-	K	-	-	-	GxGYxY sequence motif in domain of unknown function N-terminal
APPACOFM_01876	4.8e-253	-	-	-	S	-	-	-	Domain of unknown function (DUF4972)
APPACOFM_01877	3.71e-284	-	-	-	S	-	-	-	Domain of unknown function (DUF4972)
APPACOFM_01878	7.06e-299	-	3.2.1.130, 3.2.1.198	GH99	S	ko:K21132	-	ko00000,ko01000	Glycosyl hydrolase family 99
APPACOFM_01879	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2339)
APPACOFM_01880	8.87e-269	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
APPACOFM_01882	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ)
APPACOFM_01883	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycosyl hydrolase family 20, catalytic domain protein
APPACOFM_01884	5.43e-181	yaaA	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
APPACOFM_01885	4.44e-123	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
APPACOFM_01888	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
APPACOFM_01889	3.7e-217	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
APPACOFM_01890	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Psort location Cytoplasmic, score
APPACOFM_01891	8.6e-118	-	-	-	S	-	-	-	COG NOG27649 non supervised orthologous group
APPACOFM_01892	2.33e-108	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
APPACOFM_01893	1.02e-81	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
APPACOFM_01894	6.56e-188	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
APPACOFM_01895	4.26e-226	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
APPACOFM_01896	3.86e-78	-	-	-	J	ko:K03113	ko03013,map03013	ko00000,ko00001,ko03012	COG0023 Translation initiation factor 1 (eIF-1 SUI1) and related
APPACOFM_01897	2.01e-133	-	-	-	S	-	-	-	Carboxypeptidase regulatory-like domain
APPACOFM_01898	1.79e-266	-	-	-	S	-	-	-	Carboxypeptidase regulatory-like domain
APPACOFM_01899	3.17e-157	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
APPACOFM_01900	3.74e-148	fahA	-	-	Q	-	-	-	2-hydroxyhepta-2,4-diene-1,7-dioate isomerase, fumarylacetoacetate hydrolase family K01828
APPACOFM_01901	6.59e-111	ispF	4.6.1.12	-	H	ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
APPACOFM_01902	4.43e-251	-	-	-	S	-	-	-	Ser Thr phosphatase family protein
APPACOFM_01903	3.13e-64	-	-	-	S	-	-	-	COG NOG24904 non supervised orthologous group
APPACOFM_01904	3.95e-120	-	-	-	S	-	-	-	COG NOG24904 non supervised orthologous group
APPACOFM_01905	5.15e-261	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
APPACOFM_01906	0.0	aprN	-	-	M	-	-	-	Belongs to the peptidase S8 family
APPACOFM_01907	4.71e-283	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
APPACOFM_01908	1.76e-13	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
APPACOFM_01909	5.64e-256	ilvE	2.6.1.42	-	EH	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	COG0115 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase
APPACOFM_01910	1.63e-139	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
APPACOFM_01911	2.09e-210	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
APPACOFM_01912	5.7e-260	mrp	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
APPACOFM_01913	1.11e-203	-	-	-	M	ko:K03832	-	ko00000,ko02000	Gram-negative bacterial TonB protein C-terminal
APPACOFM_01914	0.0	-	-	-	CO	-	-	-	COG NOG24773 non supervised orthologous group
APPACOFM_01915	1.23e-188	-	-	-	U	-	-	-	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
APPACOFM_01916	1.91e-174	-	-	-	U	-	-	-	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
APPACOFM_01917	1.61e-293	-	-	-	L	-	-	-	COG3328 Transposase and inactivated derivatives
APPACOFM_01918	8.58e-82	-	-	-	K	-	-	-	Transcriptional regulator
APPACOFM_01920	3.09e-132	-	-	-	M	-	-	-	COG NOG19089 non supervised orthologous group
APPACOFM_01921	2e-301	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_01922	4.89e-282	-	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_01923	3.94e-210	-	-	-	M	ko:K01993	-	ko00000	Auxiliary transport protein, membrane fusion protein (MFP) family protein
APPACOFM_01924	0.0	-	-	-	MU	-	-	-	Psort location OuterMembrane, score
APPACOFM_01926	0.0	-	-	-	S	-	-	-	SWIM zinc finger
APPACOFM_01927	0.0	-	-	-	G	-	-	-	TRAP-type C4-dicarboxylate transport system periplasmic component
APPACOFM_01928	2.47e-251	-	-	-	S	-	-	-	AAA domain (dynein-related subfamily)
APPACOFM_01929	0.0	-	-	-	-	-	-	-	-
APPACOFM_01930	1.25e-264	-	-	-	S	-	-	-	VWA domain containing CoxE-like protein
APPACOFM_01931	1.66e-219	mdh	1.1.1.37	-	C	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible oxidation of malate to oxaloacetate
APPACOFM_01932	7.33e-191	-	-	-	S	-	-	-	COG NOG11650 non supervised orthologous group
APPACOFM_01933	5.16e-135	-	-	-	S	-	-	-	Domain of unknown function (DUF5034)
APPACOFM_01934	2.03e-218	-	-	-	-	-	-	-	-
APPACOFM_01935	1.81e-78	-	-	-	-	-	-	-	-
APPACOFM_01936	2.37e-220	-	-	-	L	-	-	-	Integrase core domain
APPACOFM_01937	4.86e-206	nadK	2.7.1.23	-	H	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
APPACOFM_01938	7.24e-169	pdxJ	2.6.99.2	-	H	ko:K03474	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
APPACOFM_01939	1.09e-162	exbB	-	-	U	ko:K03561	-	ko00000,ko02000	MotA TolQ ExbB proton channel family
APPACOFM_01940	2.22e-83	-	-	-	U	ko:K03559	-	ko00000,ko02000	Transport energizing protein, ExbD TolR family
APPACOFM_01941	2.05e-159	-	-	-	M	-	-	-	TonB family domain protein
APPACOFM_01942	6.84e-127	yajL	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	Psort location Cytoplasmic, score
APPACOFM_01943	1.1e-152	ispD	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
APPACOFM_01944	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
APPACOFM_01945	8.41e-107	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Nucleoside diphosphate kinase
APPACOFM_01946	5.55e-211	mepM_1	-	-	M	-	-	-	Peptidase, M23
APPACOFM_01947	5.71e-124	-	-	-	S	-	-	-	COG NOG27206 non supervised orthologous group
APPACOFM_01948	1.56e-294	doxX	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
APPACOFM_01949	3.97e-176	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
APPACOFM_01950	4.38e-102	-	-	-	S	-	-	-	Sporulation and cell division repeat protein
APPACOFM_01951	8.21e-139	folE	3.5.4.16	-	F	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase I
APPACOFM_01952	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
APPACOFM_01953	2.21e-180	tyrA	1.3.1.12	-	E	ko:K00210	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
APPACOFM_01954	1.83e-259	pheB	5.4.99.5	-	E	ko:K04516	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.96
APPACOFM_01955	3.95e-297	dapL	2.6.1.83	-	E	ko:K10206,ko:K14261	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	COG0436 Aspartate tyrosine aromatic aminotransferase
APPACOFM_01956	1.07e-204	pheA	4.2.1.51	-	E	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
APPACOFM_01957	9.64e-172	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_01958	0.0	recQ2	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
APPACOFM_01959	1.93e-260	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	single-stranded-DNA-specific exonuclease recJ
APPACOFM_01960	7.37e-122	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	single-stranded-DNA-specific exonuclease recJ
APPACOFM_01961	2.77e-220	-	-	-	G	-	-	-	COG COG4632 Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
APPACOFM_01962	1.88e-101	-	-	-	S	ko:K07107	-	ko00000,ko01000	acyl-CoA thioester hydrolase, YbgC YbaW family
APPACOFM_01963	1.06e-120	rimN	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Belongs to the SUA5 family
APPACOFM_01964	0.0	clcB	-	-	P	ko:K03281	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_01965	5.97e-224	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
APPACOFM_01966	1.02e-151	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.96
APPACOFM_01967	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_01968	1.05e-254	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHH family
APPACOFM_01969	3.42e-149	-	-	-	S	-	-	-	COG NOG30041 non supervised orthologous group
APPACOFM_01970	0.0	glmM	5.4.2.8	-	G	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.96
APPACOFM_01971	0.0	-	-	-	KT	-	-	-	Y_Y_Y domain
APPACOFM_01972	0.0	-	-	-	P	-	-	-	TonB dependent receptor
APPACOFM_01973	0.0	-	-	-	P	ko:K21572	-	ko00000,ko02000	SusD family
APPACOFM_01974	0.0	-	-	-	S	-	-	-	Peptidase of plants and bacteria
APPACOFM_01975	0.0	-	-	-	-	-	-	-	-
APPACOFM_01976	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
APPACOFM_01977	0.0	-	-	-	KT	-	-	-	Transcriptional regulator, AraC family
APPACOFM_01978	0.0	-	-	-	KT	-	-	-	Transcriptional regulator, AraC family
APPACOFM_01979	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_01980	0.0	-	-	-	P	ko:K21572	-	ko00000,ko02000	SusD family
APPACOFM_01981	0.0	-	-	-	M	-	-	-	Calpain family cysteine protease
APPACOFM_01982	4.4e-310	-	-	-	-	-	-	-	-
APPACOFM_01983	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 92
APPACOFM_01984	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 92
APPACOFM_01985	8.78e-195	-	-	-	S	-	-	-	Peptidase of plants and bacteria
APPACOFM_01986	7.58e-140	-	-	-	G	-	-	-	Glycosyl hydrolase family 92
APPACOFM_01987	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 92
APPACOFM_01989	1.45e-183	-	-	-	K	ko:K02477	-	ko00000,ko02022	LytTr DNA-binding domain protein
APPACOFM_01990	4.14e-235	-	-	-	T	-	-	-	Histidine kinase
APPACOFM_01991	1.71e-210	-	-	-	M	ko:K15727	-	ko00000,ko02000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
APPACOFM_01992	0.0	czcA	-	-	P	ko:K15726	-	ko00000,ko02000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
APPACOFM_01993	1.81e-78	-	-	-	-	-	-	-	-
APPACOFM_01994	2.37e-220	-	-	-	L	-	-	-	Integrase core domain
APPACOFM_01995	5.7e-89	-	-	-	-	-	-	-	-
APPACOFM_01996	1.97e-129	bsaA	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
APPACOFM_01997	7.16e-132	idi	-	-	I	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_01998	3.06e-303	queA	2.4.99.17	-	H	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
APPACOFM_02001	8e-188	thiD	2.7.1.49, 2.7.4.7	-	K	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	transcriptional regulator (AraC family)
APPACOFM_02003	5.25e-259	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
APPACOFM_02004	1.79e-87	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
APPACOFM_02005	0.0	-	-	-	H	-	-	-	Psort location OuterMembrane, score
APPACOFM_02006	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
APPACOFM_02007	2.14e-127	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
APPACOFM_02008	6.12e-182	-	-	-	S	-	-	-	Protein of unknown function (DUF3822)
APPACOFM_02009	3.84e-162	-	-	-	S	-	-	-	COG NOG19144 non supervised orthologous group
APPACOFM_02010	0.0	recD2_2	3.1.11.5	-	L	ko:K01144	-	ko00000,ko01000	COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member
APPACOFM_02011	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_02012	0.0	-	-	-	S	-	-	-	non supervised orthologous group
APPACOFM_02013	3.48e-246	-	-	-	S	-	-	-	Putative glycoside hydrolase Family 18, chitinase_18
APPACOFM_02014	1.77e-284	-	-	-	S	-	-	-	Domain of unknown function (DUF1735)
APPACOFM_02015	0.0	-	-	-	G	-	-	-	Psort location Extracellular, score 9.71
APPACOFM_02016	2.34e-315	-	-	-	S	-	-	-	Domain of unknown function (DUF4989)
APPACOFM_02017	1.55e-104	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_02018	0.0	-	-	-	G	-	-	-	Alpha-1,2-mannosidase
APPACOFM_02019	0.0	-	-	-	G	-	-	-	Alpha-1,2-mannosidase
APPACOFM_02020	1.26e-220	-	-	-	PT	-	-	-	COG3712 Fe2 -dicitrate sensor, membrane component
APPACOFM_02021	2.47e-125	-	-	-	K	ko:K03088	-	ko00000,ko03021	RNA polymerase sigma-70 factor
APPACOFM_02022	0.0	-	-	-	G	-	-	-	Alpha-1,2-mannosidase
APPACOFM_02023	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
APPACOFM_02024	1.26e-232	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
APPACOFM_02025	1.57e-186	-	-	-	M	-	-	-	Peptidase, M23
APPACOFM_02026	8.21e-74	ycgE	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_02027	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
APPACOFM_02028	0.0	mltD	-	-	M	ko:K08307	-	ko00000,ko01000,ko01011	Transglycosylase SLT domain
APPACOFM_02029	5.52e-209	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
APPACOFM_02030	5.04e-201	parB	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
APPACOFM_02031	9.59e-172	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain
APPACOFM_02032	3.21e-46	surE	3.1.3.5	-	S	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
APPACOFM_02033	8.84e-131	surE	3.1.3.5	-	S	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
APPACOFM_02034	2.13e-197	lpxB	2.4.1.182	GT19	M	ko:K00748	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
APPACOFM_02035	1.6e-64	lpxB	2.4.1.182	GT19	M	ko:K00748	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
APPACOFM_02036	3.06e-192	-	-	-	S	-	-	-	COG NOG29298 non supervised orthologous group
APPACOFM_02037	1.91e-197	cdsA	2.7.7.41	-	M	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
APPACOFM_02038	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
APPACOFM_02040	1.34e-253	-	-	-	L	-	-	-	Phage integrase SAM-like domain
APPACOFM_02041	6.46e-54	-	-	-	-	-	-	-	-
APPACOFM_02042	3.61e-61	-	-	-	L	-	-	-	Helix-turn-helix domain
APPACOFM_02043	7.19e-218	-	-	-	L	-	-	-	Domain of unknown function (DUF4373)
APPACOFM_02044	6.23e-47	-	-	-	-	-	-	-	-
APPACOFM_02045	1.05e-54	-	-	-	-	-	-	-	-
APPACOFM_02047	3.24e-53	-	-	-	S	-	-	-	Domain of unknown function (DUF4248)
APPACOFM_02048	6.27e-116	-	3.5.1.28	-	V	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
APPACOFM_02050	2.1e-93	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_02051	2.53e-67	-	-	-	K	-	-	-	Helix-turn-helix domain
APPACOFM_02052	5.21e-126	-	-	-	-	-	-	-	-
APPACOFM_02054	0.0	-	-	-	P	ko:K21572	-	ko00000,ko02000	SusD family
APPACOFM_02055	1.05e-57	-	-	-	H	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_02056	0.0	-	-	-	H	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_02057	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF1735)
APPACOFM_02058	0.0	-	-	-	A	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_02059	3.77e-267	mgtE	-	-	P	ko:K06213	-	ko00000,ko02000	Acts as a magnesium transporter
APPACOFM_02060	1.82e-149	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
APPACOFM_02061	4.99e-28	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
APPACOFM_02062	9.93e-235	-	-	-	S	ko:K07027	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_02063	0.0	pepD_2	-	-	E	ko:K01270	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Xaa-His dipeptidase
APPACOFM_02065	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_02066	0.0	-	-	-	S	-	-	-	COG2373 Large extracellular alpha-helical protein
APPACOFM_02067	5.99e-266	-	-	-	S	-	-	-	COG NOG19146 non supervised orthologous group
APPACOFM_02068	6.15e-259	argK	-	-	E	ko:K07588	-	ko00000,ko01000	Lao Ao transport system ATPase
APPACOFM_02069	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
APPACOFM_02070	1.2e-208	-	-	-	EG	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_02071	8.37e-205	-	-	-	P	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_02072	6.14e-238	-	-	-	P	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_02073	5.4e-309	ybdG_2	-	-	M	ko:K16053	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score
APPACOFM_02074	6.5e-214	-	-	-	K	-	-	-	Transcriptional regulator, AraC family
APPACOFM_02075	0.0	-	-	-	M	-	-	-	TonB-dependent receptor
APPACOFM_02076	5.79e-270	-	-	-	N	-	-	-	COG NOG06100 non supervised orthologous group
APPACOFM_02077	0.0	-	-	-	T	-	-	-	PAS domain S-box protein
APPACOFM_02078	0.0	nuoN	1.6.5.3	-	C	ko:K00343	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
APPACOFM_02079	0.0	nuoM	1.6.5.3	-	C	ko:K00342	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	proton-translocating NADH-quinone oxidoreductase, chain M
APPACOFM_02080	0.0	nuoL	1.6.5.3	-	CP	ko:K00341	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit
APPACOFM_02081	3.53e-63	nuoK	1.6.5.3	-	C	ko:K00340	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
APPACOFM_02082	9.81e-107	nuoJ	1.6.5.3	-	C	ko:K00339	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG0839 NADH ubiquinone oxidoreductase subunit 6 (chain J)
APPACOFM_02083	3.52e-99	nuoI	1.6.5.3	-	C	ko:K00338	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
APPACOFM_02084	2.08e-194	nuoH	1.6.5.3	-	C	ko:K00337	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
APPACOFM_02085	0.0	nuoC	1.6.5.3	-	C	ko:K00333,ko:K13378	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
APPACOFM_02086	1.17e-143	nuoB	1.6.5.3	-	C	ko:K00331	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
APPACOFM_02087	2.61e-76	nuoA	1.6.5.3	-	C	ko:K00330	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
APPACOFM_02088	1.84e-87	-	-	-	-	-	-	-	-
APPACOFM_02089	0.0	-	-	-	S	-	-	-	Psort location
APPACOFM_02090	9.82e-118	-	-	-	K	ko:K03088	-	ko00000,ko03021	Bacterial regulatory proteins, luxR family
APPACOFM_02091	6.45e-45	-	-	-	-	-	-	-	-
APPACOFM_02092	0.0	-	3.2.1.24	GH38	G	ko:K01191	ko00511,map00511	ko00000,ko00001,ko01000,ko04131	Alpha mannosidase middle domain
APPACOFM_02093	1.36e-233	-	3.2.1.24	GH38	G	ko:K01191	ko00511,map00511	ko00000,ko00001,ko01000,ko04131	Alpha mannosidase middle domain
APPACOFM_02094	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 92
APPACOFM_02095	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 2 family
APPACOFM_02096	0.0	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
APPACOFM_02097	0.0	-	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase C-terminal domain
APPACOFM_02098	3.08e-233	-	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase C-terminal domain
APPACOFM_02099	7.03e-213	xynZ	-	-	S	-	-	-	Esterase
APPACOFM_02100	2.23e-171	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
APPACOFM_02101	5.12e-214	-	-	-	-	-	-	-	-
APPACOFM_02102	4.54e-229	-	-	-	-	-	-	-	-
APPACOFM_02103	0.0	-	-	-	S	-	-	-	NHL repeat
APPACOFM_02104	0.0	-	-	-	P	-	-	-	TonB dependent receptor
APPACOFM_02105	0.0	-	-	-	P	-	-	-	SusD family
APPACOFM_02106	7.98e-253	-	-	-	S	-	-	-	Pfam:DUF5002
APPACOFM_02107	1.12e-150	-	-	-	S	-	-	-	Domain of unknown function (DUF5005)
APPACOFM_02108	1.42e-178	-	-	-	S	-	-	-	Domain of unknown function (DUF5005)
APPACOFM_02109	0.0	-	-	-	F	ko:K21572	-	ko00000,ko02000	SusD family
APPACOFM_02110	3.6e-106	-	-	-	S	-	-	-	Domain of unknown function (DUF5004)
APPACOFM_02111	2.62e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF4961)
APPACOFM_02112	4.79e-162	-	-	-	S	-	-	-	Domain of unknown function (DUF4961)
APPACOFM_02113	0.0	-	-	-	P	-	-	-	TonB-dependent Receptor Plug Domain
APPACOFM_02114	0.0	-	-	-	F	ko:K21572	-	ko00000,ko02000	SusD family
APPACOFM_02115	0.0	-	-	-	H	-	-	-	CarboxypepD_reg-like domain
APPACOFM_02116	0.0	-	3.1.1.53	-	G	ko:K05970	-	ko00000,ko01000	Glycosyl hydrolase family 2, sugar binding domain protein
APPACOFM_02117	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 92
APPACOFM_02118	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 92
APPACOFM_02119	9.92e-292	-	3.2.1.197	-	G	ko:K21065	-	ko00000,ko01000	beta-1,4-mannooligosaccharide phosphorylase
APPACOFM_02120	0.0	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
APPACOFM_02121	2.92e-113	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
APPACOFM_02122	2.3e-189	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
APPACOFM_02123	0.0	trkH	-	-	P	ko:K03498	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_02124	0.0	trkA	-	-	C	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems NAD-binding component
APPACOFM_02125	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
APPACOFM_02126	7.02e-245	-	-	-	E	-	-	-	GSCFA family
APPACOFM_02127	0.0	alr	5.1.1.1	-	M	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
APPACOFM_02128	2.62e-27	tatA	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
APPACOFM_02129	2.69e-189	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
APPACOFM_02130	0.0	-	3.6.4.12	-	L	ko:K10742	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	COG COG1112 Superfamily I DNA and RNA helicases and helicase subunits
APPACOFM_02131	0.0	exuT	-	-	G	ko:K08191	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_02132	1.74e-222	kduI	5.3.1.17	-	G	ko:K01815	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
APPACOFM_02133	0.0	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_02134	1.76e-303	-	3.2.1.172	GH105	G	ko:K15532	-	ko00000,ko01000	unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
APPACOFM_02135	1.8e-223	-	3.1.1.11	-	M	ko:K01051	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Pectinesterase
APPACOFM_02136	0.0	rhgT_2	3.1.1.11	-	EG	ko:K01051	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Psort location Extracellular, score
APPACOFM_02137	0.0	-	-	-	T	-	-	-	Psort location CytoplasmicMembrane, score
APPACOFM_02139	1.8e-299	-	-	-	S	-	-	-	Domain of unknown function (DUF5123)
APPACOFM_02140	0.0	-	-	-	GM	ko:K21572	-	ko00000,ko02000	COG NOG31573 non supervised orthologous group
APPACOFM_02141	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_02142	0.0	-	-	-	G	-	-	-	pectate lyase K01728
APPACOFM_02143	0.0	-	-	-	G	-	-	-	pectate lyase K01728
APPACOFM_02144	1.84e-196	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
APPACOFM_02145	3.39e-186	-	-	-	KT	-	-	-	COG COG3279 Response regulator of the LytR AlgR family
APPACOFM_02147	0.0	-	-	-	G	-	-	-	pectinesterase activity
APPACOFM_02148	0.0	-	-	-	S	-	-	-	Fibronectin type 3 domain
APPACOFM_02149	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_02150	0.0	-	-	-	P	ko:K21572	-	ko00000,ko02000	SusD family
APPACOFM_02151	0.0	-	-	-	G	-	-	-	Pectate lyase superfamily protein
APPACOFM_02152	1.77e-127	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
APPACOFM_02153	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
APPACOFM_02154	1.12e-18	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
APPACOFM_02155	1.74e-24	-	-	-	S	ko:K07139	-	ko00000	radical SAM protein, TIGR01212 family
APPACOFM_02156	4.91e-171	-	-	-	S	ko:K07139	-	ko00000	radical SAM protein, TIGR01212 family
APPACOFM_02157	1.06e-299	fprA	1.6.3.4	-	C	ko:K22405	-	ko00000,ko01000	anaerobic nitric oxide reductase flavorubredoxin
APPACOFM_02158	3.58e-197	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
APPACOFM_02159	3.2e-149	yciO	-	-	J	-	-	-	Belongs to the SUA5 family
APPACOFM_02160	0.0	-	-	-	M	ko:K07289	-	ko00000	protein involved in outer membrane biogenesis
APPACOFM_02161	0.0	-	-	-	L	-	-	-	COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member
APPACOFM_02162	1.02e-166	-	-	-	S	-	-	-	of the HAD superfamily
APPACOFM_02163	4.59e-294	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
APPACOFM_02164	4.18e-261	-	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
APPACOFM_02165	6.27e-67	-	-	-	L	-	-	-	Nucleotidyltransferase domain
APPACOFM_02166	1.45e-75	-	-	-	S	-	-	-	HEPN domain
APPACOFM_02167	3.09e-73	-	-	-	-	-	-	-	-
APPACOFM_02168	2.37e-220	-	-	-	L	-	-	-	Integrase core domain
APPACOFM_02169	1.81e-78	-	-	-	-	-	-	-	-
APPACOFM_02170	1.03e-279	-	-	-	K	ko:K13652	-	ko00000,ko03000	Bacterial transcription activator, effector binding domain
APPACOFM_02171	6.91e-164	-	-	-	C	-	-	-	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
APPACOFM_02172	0.0	-	-	-	L	-	-	-	transposase activity
APPACOFM_02173	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 2, sugar binding domain protein
APPACOFM_02174	0.0	-	-	-	M	-	-	-	Right handed beta helix region
APPACOFM_02176	3.34e-138	-	-	-	G	-	-	-	Domain of unknown function (DUF4450)
APPACOFM_02177	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 28 family
APPACOFM_02178	1.27e-308	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
APPACOFM_02179	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 2 family
APPACOFM_02180	4.96e-186	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 2 family
APPACOFM_02181	0.0	-	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Beta-galactosidase trimerisation domain
APPACOFM_02182	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 28 family
APPACOFM_02183	2.07e-238	-	-	-	G	-	-	-	CBM9 module, glycoside hydrolase family 8 protein and carbohydrate esterase family 4 protein K01238
APPACOFM_02184	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 28 family
APPACOFM_02185	3.97e-176	-	4.2.2.23	PL11	S	ko:K18197	-	ko00000,ko01000	candidate rhamnogalacturonan lyase, polysaccharide lyase family 11 protein K01238
APPACOFM_02186	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
APPACOFM_02187	1.8e-295	-	-	-	G	-	-	-	beta-galactosidase
APPACOFM_02188	0.0	-	-	-	G	-	-	-	beta-galactosidase
APPACOFM_02189	0.0	-	-	-	G	-	-	-	alpha-galactosidase
APPACOFM_02190	9.1e-171	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
APPACOFM_02191	0.0	-	-	-	G	-	-	-	beta-fructofuranosidase activity
APPACOFM_02192	0.0	-	-	-	G	-	-	-	Glycosyl hydrolases family 35
APPACOFM_02193	1.93e-139	-	-	-	L	-	-	-	DNA-binding protein
APPACOFM_02194	0.0	-	-	-	S	-	-	-	Domain of unknonw function from B. Theta Gene description (DUF3874)
APPACOFM_02195	0.0	-	-	-	M	-	-	-	Domain of unknown function
APPACOFM_02196	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_02197	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	Starch-binding associating with outer membrane
APPACOFM_02198	0.0	-	-	-	M	ko:K19519	-	ko00000,ko04516	Domain of unknown function (DUF5108)
APPACOFM_02199	0.0	-	-	-	M	-	-	-	COG2335, Secreted and surface protein containing fasciclin-like repeats
APPACOFM_02200	0.0	-	-	-	P	-	-	-	TonB dependent receptor
APPACOFM_02201	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	PFAM SusD family
APPACOFM_02202	0.0	-	-	-	S	-	-	-	Domain of unknown function
APPACOFM_02203	4.83e-146	-	-	-	-	-	-	-	-
APPACOFM_02205	0.0	-	-	-	-	-	-	-	-
APPACOFM_02206	0.0	-	-	-	E	-	-	-	GDSL-like protein
APPACOFM_02207	2.42e-284	yteR_10	-	-	G	-	-	-	unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
APPACOFM_02208	0.0	-	-	-	G	-	-	-	candidate rhamnogalacturonan lyase, polysaccharide lyase family 11 protein K01238
APPACOFM_02209	0.0	yteR_9	-	-	E	-	-	-	Glycosyl Hydrolase Family 88
APPACOFM_02210	4.22e-74	rhaU	5.1.3.32	-	G	ko:K03534	-	ko00000,ko01000	Involved in the anomeric conversion of L-rhamnose
APPACOFM_02211	0.0	-	-	-	T	-	-	-	Response regulator receiver domain
APPACOFM_02212	0.0	-	-	-	T	-	-	-	Response regulator receiver domain
APPACOFM_02213	0.0	-	-	-	G	-	-	-	CBM9 module, glycoside hydrolase family 8 protein and carbohydrate esterase family 4 protein K01238
APPACOFM_02214	1.52e-201	-	-	-	E	-	-	-	Carbohydrate esterase, sialic acid-specific acetylesterase
APPACOFM_02215	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
APPACOFM_02216	0.0	-	-	-	T	-	-	-	Y_Y_Y domain
APPACOFM_02217	7.99e-35	-	-	-	S	-	-	-	Domain of unknown function
APPACOFM_02218	2.11e-280	-	-	-	S	-	-	-	Domain of unknown function
APPACOFM_02219	9.11e-155	-	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD hydrolase, family IA, variant
APPACOFM_02220	0.0	xynB_10	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 43 family
APPACOFM_02221	2.86e-310	-	-	-	S	-	-	-	unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
APPACOFM_02222	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 28 family
APPACOFM_02224	1.58e-203	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
APPACOFM_02225	8.23e-247	gldB	-	-	O	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_02226	1.98e-167	rsmI_1	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Psort location Cytoplasmic, score 8.96
APPACOFM_02227	2.84e-264	-	-	-	I	-	-	-	Psort location CytoplasmicMembrane, score
APPACOFM_02228	2.55e-212	lipA	2.8.1.8	-	H	ko:K03644	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
APPACOFM_02229	1.77e-255	dpp	3.4.14.5	-	EU	ko:K01278	ko04974,map04974	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	Peptidase, S9A B C family, catalytic domain protein
APPACOFM_02230	1.86e-271	dpp	3.4.14.5	-	EU	ko:K01278	ko04974,map04974	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	Peptidase, S9A B C family, catalytic domain protein
APPACOFM_02231	4.02e-212	-	-	-	O	-	-	-	SPFH Band 7 PHB domain protein
APPACOFM_02232	8.97e-38	-	-	-	S	-	-	-	COG NOG17292 non supervised orthologous group
APPACOFM_02233	2.32e-67	-	-	-	-	-	-	-	-
APPACOFM_02234	2.55e-180	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_02235	1.05e-36	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_02236	8.58e-82	-	-	-	K	-	-	-	Transcriptional regulator, BlaI MecI CopY family
APPACOFM_02237	4.32e-146	-	-	-	-	ko:K03646	-	ko00000,ko02000	-
APPACOFM_02238	0.0	-	-	-	KT	-	-	-	COG NOG25147 non supervised orthologous group
APPACOFM_02239	9.33e-76	-	-	-	-	-	-	-	-
APPACOFM_02240	1.02e-209	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
APPACOFM_02241	3.94e-122	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_02242	6.14e-161	lpxA	2.3.1.129	-	M	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	ko00000,ko00001,ko00002,ko01000,ko01005	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
APPACOFM_02243	0.0	fabZ	3.5.1.108, 4.2.1.59	-	IM	ko:K16363	ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis
APPACOFM_02244	7.79e-163	lpxD	2.3.1.191	-	M	ko:K02536	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
APPACOFM_02245	9.77e-297	-	-	-	S	ko:K06885	-	ko00000	Psort location Cytoplasmic, score 8.96
APPACOFM_02246	8.09e-196	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the OMP decarboxylase family. Type 2 subfamily
APPACOFM_02247	1.07e-262	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
APPACOFM_02248	1.6e-180	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
APPACOFM_02249	2.06e-76	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
APPACOFM_02251	1.07e-128	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
APPACOFM_02252	3.52e-193	-	-	-	S	ko:K06872	-	ko00000	COG1512 Beta-propeller domains of methanol dehydrogenase type
APPACOFM_02253	4.85e-232	-	-	-	S	ko:K06889	-	ko00000	of the alpha beta superfamily
APPACOFM_02254	1.15e-182	aroE	1.1.1.25	-	C	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	COG0169 Shikimate 5-dehydrogenase
APPACOFM_02255	7.19e-180	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
APPACOFM_02256	7.23e-152	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
APPACOFM_02257	1.7e-45	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
APPACOFM_02258	1.28e-231	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein
APPACOFM_02259	4.33e-162	-	-	-	S	-	-	-	COG NOG26960 non supervised orthologous group
APPACOFM_02260	7.76e-238	yqiK	-	-	S	ko:K07192	ko04910,map04910	ko00000,ko00001,ko03036,ko04131,ko04147	SPFH Band 7 PHB domain protein
APPACOFM_02261	1.12e-105	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.46
APPACOFM_02262	6.6e-255	-	-	-	DK	-	-	-	Fic/DOC family
APPACOFM_02263	8.8e-14	-	-	-	K	-	-	-	Helix-turn-helix domain
APPACOFM_02265	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4906)
APPACOFM_02266	6.83e-252	-	-	-	-	-	-	-	-
APPACOFM_02267	1.68e-254	-	-	-	S	-	-	-	COG NOG32009 non supervised orthologous group
APPACOFM_02268	2.21e-313	-	-	-	S	-	-	-	Major fimbrial subunit protein type IV, Fimbrillin, C-terminal
APPACOFM_02269	1.35e-60	-	-	-	S	-	-	-	Domain of unknonw function from B. Theta Gene description (DUF3874)
APPACOFM_02270	0.0	-	-	-	K	-	-	-	Putative ATP-dependent DNA helicase recG C-terminal
APPACOFM_02271	1.27e-313	-	-	-	S	-	-	-	P-loop ATPase and inactivated derivatives
APPACOFM_02272	4.34e-151	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_02273	9.61e-23	-	-	-	S	-	-	-	Phage derived protein Gp49-like (DUF891)
APPACOFM_02274	7.13e-36	-	-	-	K	-	-	-	Helix-turn-helix domain
APPACOFM_02275	0.0	-	-	-	M	-	-	-	COG NOG23378 non supervised orthologous group
APPACOFM_02276	3.51e-141	-	-	-	M	-	-	-	Protein of unknown function (DUF3575)
APPACOFM_02277	3.05e-146	-	-	-	S	-	-	-	Domain of unknown function (DUF5033)
APPACOFM_02278	2.91e-179	-	-	-	T	-	-	-	cheY-homologous receiver domain
APPACOFM_02279	0.0	-	-	-	T	-	-	-	cheY-homologous receiver domain
APPACOFM_02280	5.72e-198	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
APPACOFM_02281	3.89e-211	-	-	-	EG	ko:K08978	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_02282	1.24e-152	-	-	-	S	-	-	-	COG NOG19149 non supervised orthologous group
APPACOFM_02283	9.97e-269	mdsC	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_02284	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	COG3250 Beta-galactosidase beta-glucuronidase
APPACOFM_02285	3.88e-211	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
APPACOFM_02286	0.0	-	-	-	S	-	-	-	Oxidoreductase NAD-binding domain protein
APPACOFM_02287	0.0	-	-	-	E	-	-	-	COG NOG04153 non supervised orthologous group
APPACOFM_02288	2.48e-312	-	-	-	S	-	-	-	Domain of unknown function (DUF1735)
APPACOFM_02289	0.0	-	-	-	P	ko:K21572	-	ko00000,ko02000	SusD family
APPACOFM_02290	0.0	-	-	-	H	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_02291	1.7e-155	-	-	-	PT	-	-	-	COG NOG28383 non supervised orthologous group
APPACOFM_02293	1.49e-120	-	-	-	K	ko:K03088	-	ko00000,ko03021	ECF sigma factor
APPACOFM_02294	0.0	-	-	-	M	-	-	-	Alpha-galactosidase. Removes both branched alpha-1,3- linked galactose residues of blood group B antigens and linear alpha-1,3-linked galactose structures
APPACOFM_02295	3.31e-302	-	-	-	S	-	-	-	hydrolase activity, acting on glycosyl bonds
APPACOFM_02298	1.13e-118	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
APPACOFM_02299	3.46e-144	-	-	-	S	-	-	-	Tetratricopeptide repeat protein
APPACOFM_02300	1.03e-264	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
APPACOFM_02301	8.02e-59	-	-	-	S	-	-	-	COG NOG38282 non supervised orthologous group
APPACOFM_02302	3.33e-203	-	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	COG COG1387 Histidinol phosphatase and related hydrolases of the PHP family
APPACOFM_02303	0.0	ctp	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
APPACOFM_02304	1.31e-103	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	Cytidine and deoxycytidylate deaminase zinc-binding region
APPACOFM_02305	3.89e-117	-	-	-	S	-	-	-	COG NOG30732 non supervised orthologous group
APPACOFM_02306	0.0	dcp	3.4.15.5, 3.4.24.70	-	E	ko:K01284,ko:K01414	-	ko00000,ko01000,ko01002	Psort location Cytoplasmic, score
APPACOFM_02307	8.84e-222	gap	1.2.1.12	-	C	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
APPACOFM_02308	3.29e-83	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
APPACOFM_02309	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
APPACOFM_02311	0.0	-	-	-	S	-	-	-	NHL repeat
APPACOFM_02312	0.0	-	-	-	P	-	-	-	TonB dependent receptor
APPACOFM_02313	0.0	-	-	-	P	-	-	-	SusD family
APPACOFM_02314	3.44e-173	-	-	-	P	-	-	-	SusD family
APPACOFM_02315	1.7e-237	-	-	-	S	-	-	-	Domain of unknown function (DUF4361)
APPACOFM_02316	2.87e-23	-	-	-	S	-	-	-	Putative binding domain, N-terminal
APPACOFM_02317	0.0	-	-	-	S	-	-	-	Putative binding domain, N-terminal
APPACOFM_02318	1.67e-159	-	-	-	-	-	-	-	-
APPACOFM_02319	2.24e-142	-	-	-	E	-	-	-	Peptidase M60-like family
APPACOFM_02320	0.0	-	-	-	E	-	-	-	Peptidase M60-like family
APPACOFM_02321	0.0	-	-	-	S	-	-	-	Erythromycin esterase
APPACOFM_02322	2.21e-17	-	-	-	S	-	-	-	Domain of unknown function (DUF5030)
APPACOFM_02323	3.17e-192	-	-	-	-	-	-	-	-
APPACOFM_02324	2.85e-100	-	-	-	-	-	-	-	-
APPACOFM_02325	8.52e-83	-	-	-	L	ko:K07497	-	ko00000	transposase activity
APPACOFM_02326	4.9e-68	-	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 like protein
APPACOFM_02327	8.17e-21	-	-	-	L	-	-	-	Transposase IS66 family
APPACOFM_02328	2.28e-198	-	-	-	L	-	-	-	Transposase IS66 family
APPACOFM_02329	3.48e-212	-	-	-	S	-	-	-	TIGRFAM methyltransferase FkbM family
APPACOFM_02330	0.0	-	-	-	M	-	-	-	Glycosyl transferases group 1
APPACOFM_02331	5.5e-200	-	-	-	M	-	-	-	Glycosyltransferase like family 2
APPACOFM_02332	2.48e-294	-	-	-	M	-	-	-	Glycosyl transferases group 1
APPACOFM_02333	6.64e-234	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
APPACOFM_02334	5.92e-235	-	-	-	S	-	-	-	Domain of unknown function (DUF5030)
APPACOFM_02335	1.06e-129	-	-	-	S	-	-	-	JAB-like toxin 1
APPACOFM_02336	1.24e-114	-	-	-	-	-	-	-	-
APPACOFM_02338	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
APPACOFM_02339	1.27e-292	-	-	-	V	-	-	-	HlyD family secretion protein
APPACOFM_02340	1.77e-177	-	-	-	L	-	-	-	Integrase core domain
APPACOFM_02341	2.41e-84	-	-	-	L	ko:K07483	-	ko00000	COG2963 Transposase and inactivated derivatives
APPACOFM_02342	0.0	-	-	-	S	-	-	-	P-loop ATPase and inactivated derivatives
APPACOFM_02343	0.0	-	-	-	H	-	-	-	COG NOG08812 non supervised orthologous group
APPACOFM_02344	1.89e-160	-	-	-	-	-	-	-	-
APPACOFM_02345	0.0	-	-	-	S	-	-	-	Fibronectin type 3 domain
APPACOFM_02346	9.51e-245	-	-	-	S	-	-	-	Domain of unknown function (DUF4361)
APPACOFM_02347	0.0	-	-	-	P	-	-	-	SusD family
APPACOFM_02348	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_02349	0.0	-	-	-	S	-	-	-	NHL repeat
APPACOFM_02350	9.46e-159	-	-	-	K	-	-	-	- catabolite gene activator and regulatory subunit of cAMP-dependent protein
APPACOFM_02351	3.73e-127	marC	-	-	U	ko:K05595	-	ko00000,ko02000	UPF0056 membrane protein
APPACOFM_02352	7.63e-143	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
APPACOFM_02353	0.0	-	-	-	G	-	-	-	glycogen debranching enzyme, archaeal type
APPACOFM_02354	0.0	gmhA	2.4.1.346	GT4	M	ko:K13668	-	ko00000,ko01000,ko01003	Glycosyltransferase, group 1 family protein
APPACOFM_02355	0.0	amyA	3.2.1.1	GH57	G	ko:K07405	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 57 family
APPACOFM_02356	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4270)
APPACOFM_02357	2.42e-199	glgA	2.4.1.21	GT5	G	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Starch synthase, catalytic domain
APPACOFM_02358	1.08e-144	panC	6.3.2.1	-	H	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
APPACOFM_02359	3.96e-37	panC	6.3.2.1	-	H	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
APPACOFM_02360	5.05e-79	panD	4.1.1.11	-	H	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
APPACOFM_02361	0.0	gltA	1.3.1.1, 1.4.1.13, 1.4.1.14	-	C	ko:K00266,ko:K17722	ko00240,ko00250,ko00410,ko00770,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00240,map00250,map00410,map00770,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 9.97
APPACOFM_02362	4.33e-270	gluP	-	-	G	ko:K02429	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_02363	6.77e-307	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Psort location Cytoplasmic, score
APPACOFM_02364	1.05e-58	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
APPACOFM_02365	1.66e-67	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
APPACOFM_02366	9.86e-153	ppaX	3.1.3.18	-	V	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD hydrolase, family IA, variant 1
APPACOFM_02367	5.82e-65	-	-	-	S	ko:K09973	-	ko00000	GumN protein
APPACOFM_02368	2.27e-111	-	-	-	S	ko:K09973	-	ko00000	GumN protein
APPACOFM_02369	2.53e-118	mepS	3.4.17.13	-	M	ko:K13694	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family
APPACOFM_02370	2.69e-165	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system ATPase component
APPACOFM_02371	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_02372	0.0	-	-	-	S	ko:K07263	-	ko00000,ko01000,ko01002	Belongs to the peptidase M16 family
APPACOFM_02373	2.13e-187	kdsA	2.5.1.55	-	H	ko:K01627	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the KdsA family
APPACOFM_02374	9.77e-230	-	-	-	I	-	-	-	lipid kinase, YegS Rv2252 BmrU family
APPACOFM_02375	2.47e-222	miaA2	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
APPACOFM_02376	0.0	-	-	-	P	-	-	-	COG NOG29071 non supervised orthologous group
APPACOFM_02377	1.06e-280	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_02378	4.68e-153	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	COG1136 ABC-type antimicrobial peptide transport system ATPase component
APPACOFM_02379	0.0	-	-	-	S	-	-	-	COG NOG26882 non supervised orthologous group
APPACOFM_02380	3.05e-170	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
APPACOFM_02381	1.12e-81	-	-	-	S	ko:K08999	-	ko00000	Conserved protein
APPACOFM_02382	1.21e-30	-	-	-	S	ko:K08999	-	ko00000	Conserved protein
APPACOFM_02383	1.58e-59	nupG	-	-	G	ko:K03289,ko:K11537	-	ko00000,ko02000	transport of nucleosides, permease protein K03289
APPACOFM_02384	1.78e-209	nupG	-	-	G	ko:K03289,ko:K11537	-	ko00000,ko02000	transport of nucleosides, permease protein K03289
APPACOFM_02385	5.38e-116	rlmI	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	SAM-dependent
APPACOFM_02386	3.55e-120	rlmI	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	SAM-dependent
APPACOFM_02387	1.69e-150	rnd	-	-	L	-	-	-	3'-5' exonuclease
APPACOFM_02388	2.94e-132	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_02389	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	COG1674 DNA segregation ATPase FtsK SpoIIIE and related
APPACOFM_02390	2.6e-149	lolA	-	-	M	ko:K03634	-	ko00000	COG NOG19151 non supervised orthologous group
APPACOFM_02391	1.28e-229	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
APPACOFM_02392	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycosyl hydrolase family 20, catalytic domain
APPACOFM_02393	2.74e-154	-	-	-	K	ko:K21556	-	ko00000,ko03000	- catabolite gene activator and regulatory subunit of cAMP-dependent protein
APPACOFM_02394	0.0	glnA	6.3.1.2	-	S	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	Glutamate--ammonia ligase, catalytic domain protein
APPACOFM_02395	5.59e-37	-	-	-	-	-	-	-	-
APPACOFM_02396	0.0	-	-	-	S	-	-	-	COG NOG25960 non supervised orthologous group
APPACOFM_02397	6.01e-268	-	-	-	L	-	-	-	Reverse transcriptase (RNA-dependent DNA polymerase)
APPACOFM_02398	0.0	recD2_4	-	-	L	-	-	-	COG COG1112 Superfamily I DNA and RNA helicases and helicase subunits
APPACOFM_02399	0.0	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence
APPACOFM_02400	3.59e-233	rnz	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
APPACOFM_02401	5.62e-126	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
APPACOFM_02402	1.19e-80	-	-	-	S	-	-	-	COG NOG23405 non supervised orthologous group
APPACOFM_02403	2.92e-103	-	-	-	S	-	-	-	COG NOG28735 non supervised orthologous group
APPACOFM_02404	6.64e-189	mazG	3.6.1.66	-	S	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.96
APPACOFM_02405	1.19e-258	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
APPACOFM_02406	1.7e-148	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.46
APPACOFM_02407	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
APPACOFM_02408	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
APPACOFM_02409	2.02e-132	-	-	-	K	ko:K03088	-	ko00000,ko03021	RNA polymerase sigma-70 factor
APPACOFM_02410	1.17e-245	-	-	-	PT	-	-	-	Sigma factor regulatory protein, FecR PupR family
APPACOFM_02411	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_02412	0.0	-	-	-	E	-	-	-	Pfam:SusD
APPACOFM_02413	0.0	-	3.2.1.50	-	G	ko:K01205	ko00531,ko01100,ko04142,map00531,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko04147	Alpha-N-acetylglucosaminidase
APPACOFM_02414	4.56e-99	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_02415	4.38e-266	-	-	-	S	-	-	-	COG NOG26558 non supervised orthologous group
APPACOFM_02416	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
APPACOFM_02417	0.0	pafA	-	-	P	-	-	-	type I phosphodiesterase nucleotide pyrophosphatase
APPACOFM_02418	1.23e-276	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
APPACOFM_02419	4.95e-161	coaX	2.7.1.33	-	F	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
APPACOFM_02420	0.0	-	-	-	I	-	-	-	Psort location OuterMembrane, score
APPACOFM_02421	7.46e-135	-	-	-	S	-	-	-	Tetratricopeptide repeat protein
APPACOFM_02422	2.8e-160	-	-	-	S	-	-	-	Tetratricopeptide repeat protein
APPACOFM_02423	8.57e-139	-	-	-	S	-	-	-	Lipopolysaccharide-assembly, LptC-related
APPACOFM_02424	2.88e-289	tlyC	-	-	S	ko:K03699	-	ko00000,ko02042	Psort location CytoplasmicMembrane, score
APPACOFM_02425	0.0	ppiD	5.2.1.8	-	O	ko:K01802,ko:K03770	-	ko00000,ko01000,ko03110	COG NOG26630 non supervised orthologous group
APPACOFM_02426	3.78e-248	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
APPACOFM_02427	1.95e-250	-	-	-	L	-	-	-	COG NOG11654 non supervised orthologous group
APPACOFM_02428	3.32e-263	pdxA	1.1.1.262	-	C	ko:K00097	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the PdxA family
APPACOFM_02429	3.37e-290	fhlA	-	-	K	-	-	-	Sigma-54 interaction domain protein
APPACOFM_02430	1.57e-119	lptE	-	-	S	-	-	-	COG NOG14471 non supervised orthologous group
APPACOFM_02431	5.92e-168	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_02432	3.04e-64	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase SecG subunit
APPACOFM_02433	0.0	-	-	-	G	-	-	-	Transporter, major facilitator family protein
APPACOFM_02434	1.07e-79	pqqD	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_02435	7.12e-62	-	-	-	-	-	-	-	-
APPACOFM_02436	3.1e-247	-	-	-	S	-	-	-	COG NOG25792 non supervised orthologous group
APPACOFM_02437	0.0	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
APPACOFM_02438	2.87e-47	-	-	-	S	-	-	-	Winged helix-turn-helix domain (DUF2582)
APPACOFM_02439	0.0	-	-	-	P	ko:K03305	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_02440	1.69e-120	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
APPACOFM_02441	2.46e-132	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
APPACOFM_02442	1.73e-268	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
APPACOFM_02443	1.17e-186	-	-	-	S	ko:K05810	-	ko00000,ko01000	Belongs to the multicopper oxidase YfiH RL5 family
APPACOFM_02444	4.86e-157	-	-	-	S	-	-	-	B3 4 domain protein
APPACOFM_02445	4.87e-148	nlpD_2	-	-	M	-	-	-	COG COG0739 Membrane proteins related to metalloendopeptidases
APPACOFM_02446	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycosyl hydrolase family 20, catalytic domain
APPACOFM_02447	0.0	-	3.2.1.35	-	G	ko:K01197	ko00531,ko01100,map00531,map01100	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	beta-N-acetylglucosaminidase
APPACOFM_02448	2.89e-220	-	-	-	K	-	-	-	AraC-like ligand binding domain
APPACOFM_02449	0.0	xylE	-	-	P	ko:K02100,ko:K03444,ko:K08138	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
APPACOFM_02450	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat protein
APPACOFM_02451	3.01e-222	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	COG2706 3-carboxymuconate cyclase
APPACOFM_02452	3.5e-70	-	-	-	S	-	-	-	COG NOG19145 non supervised orthologous group
APPACOFM_02455	7.67e-124	-	-	-	K	ko:K03088	-	ko00000,ko03021	RNA polymerase sigma-70 factor
APPACOFM_02456	2.54e-17	-	-	-	PT	-	-	-	Domain of unknown function (DUF4974)
APPACOFM_02457	5e-156	-	-	-	PT	-	-	-	Domain of unknown function (DUF4974)
APPACOFM_02459	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_02460	0.0	-	-	-	S	-	-	-	COG NOG26858 non supervised orthologous group
APPACOFM_02461	1.92e-287	-	-	-	G	-	-	-	Putative glycoside hydrolase Family 18, chitinase_18
APPACOFM_02462	6.74e-288	-	-	-	Q	-	-	-	Concanavalin A-like lectin/glucanases superfamily
APPACOFM_02463	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
APPACOFM_02464	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
APPACOFM_02465	1.92e-40	-	-	-	S	-	-	-	Domain of unknown function
APPACOFM_02466	1.22e-104	-	-	-	S	-	-	-	Domain of unknown function (DUF5126)
APPACOFM_02467	6.22e-199	-	-	-	P	ko:K21572	-	ko00000,ko02000	non supervised orthologous group
APPACOFM_02468	6.32e-177	-	-	-	H	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_02469	2.18e-230	-	-	-	L	-	-	-	COG COG3385 FOG Transposase and inactivated derivatives
APPACOFM_02470	5.68e-287	-	-	-	H	-	-	-	CarboxypepD_reg-like domain
APPACOFM_02471	4.04e-294	-	-	-	T	-	-	-	COG NOG26059 non supervised orthologous group
APPACOFM_02472	3.88e-251	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
APPACOFM_02473	1.67e-218	-	-	-	L	-	-	-	Arm DNA-binding domain
APPACOFM_02474	1.14e-47	-	-	-	L	-	-	-	Helix-turn-helix domain
APPACOFM_02475	2.26e-35	-	-	-	-	-	-	-	-
APPACOFM_02476	1.02e-241	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
APPACOFM_02477	8.76e-80	-	-	-	-	-	-	-	-
APPACOFM_02478	1.38e-60	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_02479	2.98e-207	-	-	-	U	-	-	-	Relaxase mobilization nuclease domain protein
APPACOFM_02480	8.11e-59	-	-	-	-	-	-	-	-
APPACOFM_02481	4.9e-165	-	-	-	L	-	-	-	Transposase IS4 family
APPACOFM_02482	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 9
APPACOFM_02483	3.09e-179	-	-	-	P	ko:K07214	-	ko00000	Putative esterase
APPACOFM_02484	0.0	-	3.2.1.156	GH8	G	ko:K15531	-	ko00000,ko01000	Glycosyl hydrolases family 8
APPACOFM_02485	3.49e-229	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 43 family
APPACOFM_02487	2.56e-110	-	-	-	S	ko:K07005	-	ko00000	Pyridoxamine 5'-phosphate oxidase
APPACOFM_02488	4.07e-92	-	-	-	S	-	-	-	Protein of unknown function (DUF3788)
APPACOFM_02489	1.4e-42	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
APPACOFM_02490	0.0	-	3.2.1.51	GH95	G	ko:K15923	ko00511,map00511	ko00000,ko00001,ko01000	COG NOG04001 non supervised orthologous group
APPACOFM_02491	6.15e-187	-	-	-	Q	-	-	-	COG NOG10855 non supervised orthologous group
APPACOFM_02492	8.96e-251	-	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
APPACOFM_02493	2.74e-176	opuAC	-	-	E	ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, QAT family
APPACOFM_02494	8.4e-08	opuAC	-	-	E	ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, QAT family
APPACOFM_02495	1.32e-184	opuAB	-	-	P	ko:K02001	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine transport system, permease
APPACOFM_02496	1.84e-280	proV	3.6.3.32	-	P	ko:K02000	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG4175 ABC-type proline glycine betaine transport system, ATPase component
APPACOFM_02497	8.49e-290	-	-	-	P	-	-	-	phosphate-selective porin O and P
APPACOFM_02498	8.03e-112	-	-	-	K	ko:K13652	-	ko00000,ko03000	methylphosphotriester-DNA alkyltransferase (AraC XylS family)
APPACOFM_02499	6.58e-65	-	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
APPACOFM_02500	4.85e-37	XK27_07105	-	-	K	ko:K07729	-	ko00000,ko03000	sequence-specific DNA binding
APPACOFM_02501	2.18e-230	-	-	-	L	-	-	-	COG COG3385 FOG Transposase and inactivated derivatives
APPACOFM_02503	8.71e-13	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
APPACOFM_02504	5.21e-230	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
APPACOFM_02505	0.0	-	-	-	S	-	-	-	COG NOG25375 non supervised orthologous group
APPACOFM_02506	1.19e-163	-	-	-	S	-	-	-	Domain of unknown function (DUF4627)
APPACOFM_02507	6.18e-23	-	-	-	-	-	-	-	-
APPACOFM_02508	0.0	-	-	-	E	-	-	-	Transglutaminase-like protein
APPACOFM_02509	1.61e-102	-	-	-	-	-	-	-	-
APPACOFM_02510	5.44e-88	-	-	-	S	-	-	-	COG NOG30410 non supervised orthologous group
APPACOFM_02511	5.24e-278	madB	4.1.1.3	-	C	ko:K01572	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	COG COG1883 Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
APPACOFM_02512	1.5e-174	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
APPACOFM_02513	0.0	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
APPACOFM_02514	2.47e-58	-	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
APPACOFM_02515	6.13e-59	-	-	-	S	-	-	-	COG NOG23407 non supervised orthologous group
APPACOFM_02516	1.33e-252	-	-	-	G	-	-	-	SMP-30/Gluconolaconase/LRE-like region
APPACOFM_02517	7.25e-93	-	-	-	-	-	-	-	-
APPACOFM_02518	1.75e-115	-	-	-	-	-	-	-	-
APPACOFM_02519	0.0	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Carbohydrate kinase, FGGY family protein
APPACOFM_02520	3.5e-248	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
APPACOFM_02521	2.12e-164	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
APPACOFM_02522	0.0	-	-	-	U	-	-	-	Involved in the tonB-independent uptake of proteins
APPACOFM_02523	2.68e-215	-	-	-	C	-	-	-	cytochrome c peroxidase
APPACOFM_02524	1.63e-210	-	-	-	C	-	-	-	cytochrome c peroxidase
APPACOFM_02525	1.61e-222	-	-	-	S	-	-	-	unsaturated rhamnogalacturonyl hydrolase activity
APPACOFM_02526	1.17e-267	-	-	-	J	-	-	-	endoribonuclease L-PSP
APPACOFM_02527	0.0	ccmC	-	-	O	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_02528	0.0	-	-	-	JKL	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_02529	1.71e-91	-	-	-	L	-	-	-	Bacterial DNA-binding protein
APPACOFM_02531	6.48e-104	-	-	-	-	-	-	-	-
APPACOFM_02532	4.7e-108	-	-	-	-	-	-	-	-
APPACOFM_02533	5.63e-163	-	-	-	-	-	-	-	-
APPACOFM_02534	3.38e-159	-	-	-	N	-	-	-	Bacterial Ig-like domain (group 2)
APPACOFM_02535	2.21e-295	-	-	-	L	-	-	-	COG3328 Transposase and inactivated derivatives
APPACOFM_02536	2.78e-111	-	-	-	S	-	-	-	Domain of unknown function (DUF4468) with TBP-like fold
APPACOFM_02540	1.19e-117	-	-	-	O	-	-	-	tape measure
APPACOFM_02541	1.16e-61	-	-	-	-	-	-	-	-
APPACOFM_02542	1.1e-66	-	-	-	S	-	-	-	Phage minor structural protein
APPACOFM_02543	0.0	-	-	-	S	-	-	-	Phage minor structural protein
APPACOFM_02544	1.67e-123	-	-	-	S	-	-	-	Phage minor structural protein
APPACOFM_02546	0.0	-	-	-	S	-	-	-	regulation of response to stimulus
APPACOFM_02549	1.84e-76	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_02550	2.28e-141	-	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	COG NOG32858 non supervised orthologous group
APPACOFM_02551	1.94e-81	-	-	-	-	-	-	-	-
APPACOFM_02553	9.48e-139	-	-	-	H	-	-	-	COG NOG08812 non supervised orthologous group
APPACOFM_02554	1.6e-259	-	-	-	H	-	-	-	COG NOG08812 non supervised orthologous group
APPACOFM_02555	4.37e-214	-	-	-	M	-	-	-	COG COG1082 Sugar phosphate isomerases epimerases
APPACOFM_02556	2.19e-217	-	-	-	G	-	-	-	COG NOG16664 non supervised orthologous group
APPACOFM_02557	7.82e-98	-	-	-	S	-	-	-	Tat pathway signal sequence domain protein
APPACOFM_02558	2.09e-247	-	-	-	S	-	-	-	Tat pathway signal sequence domain protein
APPACOFM_02559	9.85e-156	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_02560	1.17e-71	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_02561	3.83e-229	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_02562	6.37e-48	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_02563	2.21e-75	mtnN	3.2.2.9	-	F	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.96
APPACOFM_02564	4.82e-78	-	-	-	S	ko:K09790	-	ko00000	Psort location CytoplasmicMembrane, score
APPACOFM_02565	3.33e-85	queD	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	Psort location Cytoplasmic, score
APPACOFM_02566	4.48e-136	queE	4.3.99.3	-	H	ko:K10026	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
APPACOFM_02567	5.69e-182	-	-	-	C	ko:K18928	-	ko00000	Psort location Cytoplasmic, score 8.96
APPACOFM_02568	2.02e-233	-	-	-	C	ko:K18929	-	ko00000	electron transport protein YkgF
APPACOFM_02569	7.52e-85	-	-	-	C	ko:K18929	-	ko00000	electron transport protein YkgF
APPACOFM_02570	4.75e-132	lutC	-	-	S	ko:K00782	-	ko00000	Psort location Cytoplasmic, score 8.96
APPACOFM_02571	3.34e-212	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Pyridoxal kinase
APPACOFM_02572	3.31e-283	-	-	-	S	ko:K07148	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_02573	3.2e-288	-	-	-	M	-	-	-	Carboxypeptidase regulatory-like domain
APPACOFM_02574	6.47e-126	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
APPACOFM_02575	7.08e-37	-	-	-	S	ko:K07114	-	ko00000,ko02000	Von Willebrand factor type A domain protein
APPACOFM_02576	0.0	-	-	-	S	ko:K07114	-	ko00000,ko02000	Von Willebrand factor type A domain protein
APPACOFM_02578	3.69e-81	-	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
APPACOFM_02579	2.32e-118	mug	-	-	L	-	-	-	COG3663 G T U mismatch-specific DNA glycosylase
APPACOFM_02580	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_02581	0.0	-	-	-	S	-	-	-	COG NOG26858 non supervised orthologous group
APPACOFM_02582	8.76e-176	-	-	-	S	-	-	-	COG NOG09956 non supervised orthologous group
APPACOFM_02583	2.94e-298	pbuX	-	-	F	ko:K16345	-	ko00000,ko02000	xanthine permease
APPACOFM_02584	0.0	eam	5.4.3.2	-	E	ko:K01843	ko00310,map00310	ko00000,ko00001,ko01000	KamA family
APPACOFM_02585	1.52e-150	-	-	-	S	-	-	-	COG NOG25304 non supervised orthologous group
APPACOFM_02586	0.0	agcS	-	-	E	ko:K03310	-	ko00000	amino acid carrier protein
APPACOFM_02587	6.93e-154	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_02588	1.62e-28	-	-	-	S	-	-	-	COG NOG16623 non supervised orthologous group
APPACOFM_02589	9.08e-224	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
APPACOFM_02590	0.0	-	-	-	N	-	-	-	bacterial-type flagellum assembly
APPACOFM_02591	8.87e-247	-	-	-	M	-	-	-	COG2885 Outer membrane protein and related peptidoglycan-associated
APPACOFM_02593	7.04e-308	-	-	-	S	-	-	-	DNA-binding protein with the Helix-hairpin-helix motif
APPACOFM_02594	1.84e-70	-	-	-	L	-	-	-	DNA metabolism protein
APPACOFM_02595	1.49e-54	-	-	-	L	-	-	-	DNA metabolism protein
APPACOFM_02596	3.76e-141	mgtC	-	-	S	ko:K07507	-	ko00000,ko02000	Mg2 transporter-C family protein
APPACOFM_02597	2.37e-79	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.46
APPACOFM_02598	1.57e-188	-	-	-	J	ko:K10716	-	ko00000,ko02000	Transporter, cation channel family protein
APPACOFM_02599	4.01e-242	mltD_2	-	-	M	-	-	-	Transglycosylase SLT domain protein
APPACOFM_02600	1.03e-205	-	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Formamidopyrimidine-DNA glycosylase H2TH domain
APPACOFM_02602	0.0	-	-	-	-	-	-	-	-
APPACOFM_02603	8.95e-140	-	-	-	S	-	-	-	Domain of unknown function (DUF5025)
APPACOFM_02604	1.29e-84	-	-	-	-	-	-	-	-
APPACOFM_02605	0.0	-	-	-	NU	-	-	-	Type IV pilus biogenesis stability protein PilW
APPACOFM_02606	3.23e-211	-	-	-	M	ko:K07071	-	ko00000	Domain of unknown function (DUF1731)
APPACOFM_02607	6.83e-96	-	-	-	M	ko:K07071	-	ko00000	Domain of unknown function (DUF1731)
APPACOFM_02608	9.54e-61	-	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
APPACOFM_02609	4.6e-62	-	-	-	S	-	-	-	COG NOG23408 non supervised orthologous group
APPACOFM_02610	5.61e-167	-	-	-	S	-	-	-	Oxidoreductase, short chain dehydrogenase reductase family protein
APPACOFM_02611	6.11e-68	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_02612	6.64e-56	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_02613	2.93e-313	mepA_7	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_02614	1.2e-234	-	-	-	S	-	-	-	Fimbrillin-like
APPACOFM_02615	3.44e-229	rluA	5.4.99.28, 5.4.99.29	-	J	ko:K06177	-	ko00000,ko01000,ko03009,ko03016	Pseudouridine synthase, RluA family
APPACOFM_02616	2.45e-142	rluA	5.4.99.28, 5.4.99.29	-	J	ko:K06177	-	ko00000,ko01000,ko03009,ko03016	Pseudouridine synthase, RluA family
APPACOFM_02617	3.3e-126	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
APPACOFM_02618	6.92e-106	nodN	-	-	I	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_02619	2.11e-148	-	-	-	U	ko:K05595	-	ko00000,ko02000	MarC family integral membrane protein
APPACOFM_02620	3.68e-125	-	-	-	S	-	-	-	COG NOG35345 non supervised orthologous group
APPACOFM_02621	0.0	gloA	4.4.1.5	-	E	ko:K01759,ko:K03827	ko00620,map00620	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
APPACOFM_02622	2.34e-209	per1	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	COG2367 Beta-lactamase class A
APPACOFM_02623	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_02624	9.03e-297	-	-	-	S	-	-	-	SEC-C motif
APPACOFM_02625	3.23e-193	-	-	-	S	-	-	-	HEPN domain
APPACOFM_02626	0.0	-	-	-	L	-	-	-	transposase activity
APPACOFM_02627	0.0	-	-	-	S	-	-	-	P-loop ATPase and inactivated derivatives
APPACOFM_02628	3.25e-106	-	-	-	S	-	-	-	COG NOG19145 non supervised orthologous group
APPACOFM_02629	1.41e-266	yjmD_2	-	-	E	ko:K18369	ko00640,map00640	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
APPACOFM_02630	1.44e-185	spoU	-	-	H	ko:K03437	-	ko00000,ko03016	RNA methyltransferase TrmH family
APPACOFM_02631	3.43e-196	-	-	-	-	-	-	-	-
APPACOFM_02632	1.08e-38	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
APPACOFM_02633	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF1524)
APPACOFM_02634	0.0	-	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	COG COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
APPACOFM_02635	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	HsdM N-terminal domain
APPACOFM_02636	1e-270	-	-	-	S	-	-	-	Protein of unknown function (DUF1016)
APPACOFM_02638	1.83e-236	-	3.1.21.3	-	L	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
APPACOFM_02639	1.15e-121	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
APPACOFM_02640	2.15e-192	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
APPACOFM_02641	9.21e-107	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	type I restriction
APPACOFM_02642	2.67e-62	-	-	-	L	-	-	-	DNA binding domain, excisionase family
APPACOFM_02643	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
APPACOFM_02644	0.0	-	-	-	T	-	-	-	Histidine kinase
APPACOFM_02645	2.66e-33	-	-	-	T	-	-	-	Histidine kinase
APPACOFM_02646	9.82e-156	-	-	-	S	ko:K07118	-	ko00000	NmrA-like family
APPACOFM_02647	1.73e-215	udp	2.4.2.3	-	F	ko:K00757	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
APPACOFM_02648	6.27e-209	-	-	-	S	-	-	-	UPF0365 protein
APPACOFM_02649	4.37e-85	-	-	-	O	-	-	-	Psort location CytoplasmicMembrane, score
APPACOFM_02650	0.0	-	-	-	S	-	-	-	COG NOG11656 non supervised orthologous group
APPACOFM_02651	1.44e-176	ttcA	-	-	H	ko:K14058	-	ko00000,ko03016	Belongs to the TtcA family
APPACOFM_02652	1.72e-82	-	-	-	S	ko:K09922	-	ko00000	Psort location CytoplasmicMembrane, score
APPACOFM_02653	1.03e-24	-	-	-	E	-	-	-	Aminopeptidase I zinc metalloprotease (M18)
APPACOFM_02654	9.64e-293	-	-	-	E	-	-	-	Aminopeptidase I zinc metalloprotease (M18)
APPACOFM_02655	2.2e-248	-	-	-	C	ko:K06871	-	ko00000	radical SAM domain protein
APPACOFM_02658	3.96e-18	-	-	-	-	-	-	-	-
APPACOFM_02659	2.78e-255	-	-	-	S	-	-	-	P-loop ATPase and inactivated derivatives
APPACOFM_02660	9.56e-130	-	-	-	L	-	-	-	Bacterial DNA-binding protein
APPACOFM_02661	4.81e-231	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
APPACOFM_02662	3.32e-128	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
APPACOFM_02663	8.49e-165	-	-	-	S	-	-	-	COG NOG28307 non supervised orthologous group
APPACOFM_02664	2.65e-110	-	-	-	S	-	-	-	COG NOG30522 non supervised orthologous group
APPACOFM_02665	3.29e-232	arnC	-	-	M	-	-	-	involved in cell wall biogenesis
APPACOFM_02666	7.47e-125	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
APPACOFM_02668	4.59e-73	-	-	-	K	-	-	-	LytTr DNA-binding domain
APPACOFM_02669	8.3e-64	-	-	-	K	-	-	-	LytTr DNA-binding domain
APPACOFM_02670	4.38e-243	-	-	-	T	-	-	-	Histidine kinase
APPACOFM_02671	0.0	-	-	-	P	-	-	-	Outer membrane protein beta-barrel family
APPACOFM_02672	2.3e-184	-	-	-	-	-	-	-	-
APPACOFM_02673	1.5e-55	-	-	-	-	-	-	-	-
APPACOFM_02674	8.18e-89	-	-	-	-	-	-	-	-
APPACOFM_02675	4.44e-127	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70, region 4
APPACOFM_02676	6.5e-306	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
APPACOFM_02677	8.42e-69	-	-	-	S	-	-	-	Pentapeptide repeat protein
APPACOFM_02678	7.85e-84	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
APPACOFM_02679	1.2e-189	-	-	-	-	-	-	-	-
APPACOFM_02680	1.4e-198	-	-	-	M	-	-	-	Peptidase family M23
APPACOFM_02681	1.81e-78	-	-	-	-	-	-	-	-
APPACOFM_02682	2.37e-220	-	-	-	L	-	-	-	Integrase core domain
APPACOFM_02683	1.05e-36	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_02684	2.55e-180	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_02686	0.0	susB	3.2.1.20, 3.2.1.3	GH31,GH97	G	ko:K01187,ko:K21574	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG NOG06228 non supervised orthologous group
APPACOFM_02688	6.26e-211	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	glutamine phosphoribosylpyrophosphate amidotransferase
APPACOFM_02689	1.24e-298	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
APPACOFM_02690	3.1e-271	gcvT	2.1.2.10	-	H	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	The glycine cleavage system catalyzes the degradation of glycine
APPACOFM_02691	0.0	nhaA	-	-	P	ko:K03455	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_02692	5.79e-70	nhaA	-	-	P	ko:K03455	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_02693	5.66e-101	-	-	-	FG	-	-	-	Histidine triad domain protein
APPACOFM_02694	3.03e-91	hslR	-	-	J	ko:K04762	-	ko00000,ko03110	COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
APPACOFM_02695	6.55e-137	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
APPACOFM_02696	3.45e-131	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
APPACOFM_02697	9.96e-85	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_02698	8.74e-208	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
APPACOFM_02699	7.89e-57	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	COG1862 Preprotein translocase subunit YajC
APPACOFM_02700	3.31e-238	-	-	-	S	-	-	-	COG NOG14472 non supervised orthologous group
APPACOFM_02701	6.42e-140	coaE	2.7.1.24	-	H	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
APPACOFM_02702	3.12e-95	-	-	-	S	-	-	-	COG NOG14473 non supervised orthologous group
APPACOFM_02703	6.88e-54	-	-	-	-	-	-	-	-
APPACOFM_02704	0.0	clpB	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
APPACOFM_02705	2.26e-135	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_02706	2.43e-209	cysL	-	-	K	-	-	-	LysR substrate binding domain protein
APPACOFM_02707	0.0	-	-	-	H	-	-	-	COG NOG08812 non supervised orthologous group
APPACOFM_02709	2.51e-150	-	-	-	L	-	-	-	COG NOG29822 non supervised orthologous group
APPACOFM_02710	0.0	-	-	-	O	-	-	-	Hsp70 protein
APPACOFM_02711	1.73e-289	-	-	-	L	-	-	-	Viral (Superfamily 1) RNA helicase
APPACOFM_02712	1.96e-253	-	-	-	-	-	-	-	-
APPACOFM_02713	0.0	-	-	-	N	-	-	-	Putative binding domain, N-terminal
APPACOFM_02714	3.56e-280	-	-	-	S	-	-	-	Domain of unknown function
APPACOFM_02715	5.57e-104	-	-	-	S	-	-	-	Protein of unknown function (DUF1810)
APPACOFM_02716	9.18e-83	yccF	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
APPACOFM_02717	7.7e-229	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_02718	1.46e-240	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
APPACOFM_02719	7.84e-106	bcp	1.11.1.15	-	O	ko:K03564	-	ko00000,ko01000	bacterioferritin comigratory protein
APPACOFM_02720	2.71e-306	LYS1	1.5.1.7	-	E	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	COG1748 Saccharopine dehydrogenase and related
APPACOFM_02721	3.89e-316	-	-	-	-	-	-	-	-
APPACOFM_02722	3.23e-94	-	-	-	O	-	-	-	META domain
APPACOFM_02723	9.44e-76	-	-	-	O	-	-	-	META domain
APPACOFM_02724	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
APPACOFM_02726	3.03e-127	-	-	-	L	-	-	-	DNA binding domain, excisionase family
APPACOFM_02727	1.52e-301	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
APPACOFM_02728	2.92e-78	-	-	-	L	-	-	-	Helix-turn-helix domain
APPACOFM_02729	9.41e-83	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_02730	0.0	-	-	-	L	-	-	-	COG NOG25561 non supervised orthologous group
APPACOFM_02731	3.38e-81	-	-	-	S	-	-	-	Bacterial mobilisation protein (MobC)
APPACOFM_02732	2.53e-191	-	-	-	U	-	-	-	Relaxase/Mobilisation nuclease domain
APPACOFM_02733	1.57e-129	-	-	-	-	-	-	-	-
APPACOFM_02734	8.04e-111	vsr	-	-	L	ko:K07458	-	ko00000,ko01000,ko03400	May nick specific sequences that contain T G mispairs resulting from m5C-deamination
APPACOFM_02735	0.0	-	-	-	-	-	-	-	-
APPACOFM_02736	0.0	-	-	-	S	ko:K09124	-	ko00000	PD-(D/E)XK nuclease superfamily
APPACOFM_02737	0.0	-	-	-	V	-	-	-	to Escherichia coli 5-methylcytosine-specific restriction enzyme B McrB or RglB or B4346 SWALL MCRB_ECOLI (SWALL P15005) (459 aa) fasta scores E() 7.3e-21, 29.42 id in 333 aa, and to Bacillus cereus 5-methylcytosine-specific restriction related enzyme McrB SWALL Q9XBI7 (EMBL AJ007510) (343 aa) fasta scores E() 6e-14, 32.38 id in 281 aa
APPACOFM_02738	8.35e-237	dcm	2.1.1.37	-	H	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	C-5 cytosine-specific DNA methylase
APPACOFM_02739	4.77e-42	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
APPACOFM_02740	1.79e-181	-	-	-	L	-	-	-	Restriction endonuclease
APPACOFM_02741	2.12e-141	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
APPACOFM_02742	2e-301	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	domain shared with the mammalian protein Schlafen
APPACOFM_02743	8.56e-59	-	-	-	-	-	-	-	-
APPACOFM_02744	0.0	arsA	-	-	P	-	-	-	COG COG3119 Arylsulfatase A and related enzymes
APPACOFM_02745	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF1735)
APPACOFM_02746	0.0	-	-	-	P	ko:K21572	-	ko00000,ko02000	SusD family
APPACOFM_02747	2.12e-60	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_02748	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_02749	1.47e-119	-	-	-	PT	-	-	-	Sigma factor regulatory protein, FecR PupR family
APPACOFM_02750	1.41e-100	-	-	-	PT	-	-	-	Sigma factor regulatory protein, FecR PupR family
APPACOFM_02751	9.32e-80	-	-	-	K	-	-	-	RNA polymerase sigma-70 factor, ECF subfamily
APPACOFM_02752	7.08e-39	-	-	-	K	-	-	-	RNA polymerase sigma-70 factor, ECF subfamily
APPACOFM_02753	8.72e-235	pitA	-	-	P	ko:K03306	-	ko00000	Phosphate transporter family
APPACOFM_02754	1.83e-149	-	-	-	P	ko:K07220	-	ko00000	COG1392 Phosphate transport regulator (distant homolog of PhoU)
APPACOFM_02755	5.26e-148	-	-	-	S	ko:K03975	-	ko00000	Psort location CytoplasmicMembrane, score
APPACOFM_02756	1.66e-100	-	-	-	-	-	-	-	-
APPACOFM_02757	9.67e-104	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
APPACOFM_02758	1.41e-305	-	-	-	S	-	-	-	CarboxypepD_reg-like domain
APPACOFM_02759	1.49e-121	-	-	-	K	ko:K03088	-	ko00000,ko03021	RNA polymerase sigma-70 factor
APPACOFM_02760	3.58e-202	-	-	-	PT	-	-	-	Sigma factor regulatory protein, FecR PupR family
APPACOFM_02761	0.0	-	-	-	S	-	-	-	CarboxypepD_reg-like domain
APPACOFM_02762	5.36e-36	-	-	-	S	-	-	-	COG NOG17973 non supervised orthologous group
APPACOFM_02763	1.19e-120	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70, region 4
APPACOFM_02764	8.01e-77	-	-	-	-	-	-	-	-
APPACOFM_02765	7.51e-125	-	-	-	-	-	-	-	-
APPACOFM_02766	0.0	-	-	-	P	-	-	-	ATP synthase F0, A subunit
APPACOFM_02767	2.43e-203	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
APPACOFM_02768	0.0	hepB	-	-	S	-	-	-	Heparinase II III-like protein
APPACOFM_02769	8.65e-206	-	-	-	G	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_02770	1.55e-226	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
APPACOFM_02771	0.0	-	-	-	S	-	-	-	PHP domain protein
APPACOFM_02772	0.0	-	-	-	P	-	-	-	COG COG3119 Arylsulfatase A and related enzymes
APPACOFM_02773	0.0	-	4.2.2.8	PL12	M	ko:K19052	-	ko00000,ko01000	Heparinase II III-like protein
APPACOFM_02774	0.0	-	-	-	S	-	-	-	Glycosyl Hydrolase Family 88
APPACOFM_02775	0.0	-	3.2.1.51	GH95	G	ko:K15923	ko00511,map00511	ko00000,ko00001,ko01000	COG NOG04001 non supervised orthologous group
APPACOFM_02776	1.72e-162	-	-	-	G	-	-	-	Lyase, N terminal
APPACOFM_02777	0.0	-	-	-	G	-	-	-	Lyase, N terminal
APPACOFM_02778	0.0	-	-	-	GM	ko:K21572	-	ko00000,ko02000	Pfam:SusD
APPACOFM_02779	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_02780	1.17e-216	-	-	-	S	-	-	-	Domain of unknown function (DUF4958)
APPACOFM_02781	0.0	-	4.2.2.8	PL12	M	ko:K19052	-	ko00000,ko01000	Heparinase II III-like protein
APPACOFM_02782	0.0	-	3.2.1.51	GH95	G	ko:K15923	ko00511,map00511	ko00000,ko00001,ko01000	COG NOG04001 non supervised orthologous group
APPACOFM_02783	1.38e-246	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
APPACOFM_02784	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
APPACOFM_02785	0.0	trpB	4.2.1.20	-	E	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
APPACOFM_02786	2.24e-314	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_02788	1.01e-157	ktrA	-	-	C	ko:K03499	-	ko00000,ko02000	Psort location Cytoplasmic, score 8.96
APPACOFM_02789	2.3e-257	-	-	-	S	-	-	-	Endonuclease Exonuclease phosphatase family
APPACOFM_02790	8e-146	-	-	-	S	-	-	-	cellulose binding
APPACOFM_02792	5e-159	-	-	-	O	-	-	-	Peptidase, S8 S53 family
APPACOFM_02793	1.01e-68	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_02794	4.48e-67	-	-	-	M	-	-	-	Chaperone of endosialidase
APPACOFM_02799	5.87e-76	-	-	-	L	-	-	-	COG NOG14720 non supervised orthologous group
APPACOFM_02802	8.26e-49	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
APPACOFM_02803	9.12e-115	-	2.3.1.29, 2.3.1.47	-	E	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Beta-eliminating lyase
APPACOFM_02804	1.33e-37	-	2.3.1.29, 2.3.1.47	-	E	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Beta-eliminating lyase
APPACOFM_02807	2.37e-220	-	-	-	L	-	-	-	Integrase core domain
APPACOFM_02808	1.81e-78	-	-	-	-	-	-	-	-
APPACOFM_02809	1.68e-143	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
APPACOFM_02810	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
APPACOFM_02811	9.33e-125	-	-	-	S	-	-	-	COG NOG28695 non supervised orthologous group
APPACOFM_02812	5.64e-288	-	4.2.2.7	PL13	M	ko:K19050	-	ko00000,ko01000	Heparin lyase
APPACOFM_02813	4.07e-97	-	-	-	S	-	-	-	COG NOG31508 non supervised orthologous group
APPACOFM_02814	5.15e-125	-	-	-	S	-	-	-	COG NOG31242 non supervised orthologous group
APPACOFM_02815	3.37e-298	sdaA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	COG1760 L-serine deaminase
APPACOFM_02816	1.1e-254	corA	-	-	P	ko:K03284	-	ko00000,ko02000	Mediates influx of magnesium ions
APPACOFM_02818	2.18e-230	-	-	-	L	-	-	-	COG COG3385 FOG Transposase and inactivated derivatives
APPACOFM_02820	1.69e-19	-	-	-	-	-	-	-	-
APPACOFM_02822	5.74e-291	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_02823	1.24e-217	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_02824	3.79e-250	-	-	-	T	-	-	-	AAA domain
APPACOFM_02825	4.15e-56	-	-	-	S	-	-	-	Protein of unknown function (DUF3853)
APPACOFM_02828	1.96e-216	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_02829	3.88e-301	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_02830	2.29e-311	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
APPACOFM_02831	8.02e-45	-	-	-	S	-	-	-	Domain of unknown function (DUF4361)
APPACOFM_02832	3.04e-110	-	-	-	P	ko:K21572	-	ko00000,ko02000	SusD family
APPACOFM_02833	4.84e-65	-	-	-	P	-	-	-	SusD family
APPACOFM_02834	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_02835	1.53e-20	-	-	-	S	-	-	-	NHL repeat
APPACOFM_02836	1.68e-132	-	-	-	S	-	-	-	NHL repeat
APPACOFM_02837	5.18e-229	-	-	-	G	-	-	-	Histidine acid phosphatase
APPACOFM_02838	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycosyl hydrolase family 20, catalytic domain
APPACOFM_02839	0.0	-	3.2.1.51	GH95	G	ko:K15923	ko00511,map00511	ko00000,ko00001,ko01000	COG NOG04001 non supervised orthologous group
APPACOFM_02841	0.0	-	3.1.6.1	-	P	ko:K01130	ko00140,ko00600,map00140,map00600	ko00000,ko00001,ko01000	COG COG3119 Arylsulfatase A and related enzymes
APPACOFM_02842	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
APPACOFM_02843	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	SusD family
APPACOFM_02844	1.75e-101	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_02845	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_02846	1.69e-170	-	-	-	PT	-	-	-	Sigma factor regulatory protein, FecR PupR family
APPACOFM_02847	5.58e-103	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70, region 4
APPACOFM_02849	2.85e-243	-	-	-	M	ko:K16052	-	ko00000,ko02000	Mechanosensitive ion channel
APPACOFM_02850	0.0	-	3.2.1.41	CBM48,GH13	G	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
APPACOFM_02851	2.18e-230	-	-	-	L	-	-	-	COG COG3385 FOG Transposase and inactivated derivatives
APPACOFM_02852	6.59e-287	amyS	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Alpha-amylase domain
APPACOFM_02853	1.15e-232	rlmF	2.1.1.181	-	J	ko:K06970	-	ko00000,ko01000,ko03009	Specifically methylates the adenine in position 1618 of 23S rRNA
APPACOFM_02854	0.0	-	-	-	-	-	-	-	-
APPACOFM_02855	3.15e-254	-	-	-	M	ko:K15727	-	ko00000,ko02000	Barrel-sandwich domain of CusB or HlyD membrane-fusion
APPACOFM_02856	0.0	-	-	-	P	ko:K15726	-	ko00000,ko02000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
APPACOFM_02857	3.9e-286	czcC_2	-	-	MU	ko:K15725	-	ko00000,ko02000	Outer membrane efflux protein
APPACOFM_02858	2.23e-188	-	-	-	M	-	-	-	COG NOG10981 non supervised orthologous group
APPACOFM_02859	0.0	-	-	-	K	-	-	-	COG NOG18216 non supervised orthologous group
APPACOFM_02860	1.27e-87	-	-	-	S	-	-	-	Protein of unknown function, DUF488
APPACOFM_02861	8.32e-294	ydiI	3.1.2.28	-	Q	ko:K19222	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.96
APPACOFM_02862	1.75e-277	entC	5.4.4.2	-	HQ	ko:K02361,ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
APPACOFM_02863	0.0	menD	2.2.1.9	-	H	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
APPACOFM_02864	6.93e-197	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
APPACOFM_02865	2.92e-259	menC	-	-	M	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_02866	8.78e-263	menE	6.2.1.26	-	IQ	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.96
APPACOFM_02867	3e-133	-	-	-	K	ko:K03088	-	ko00000,ko03021	RNA polymerase sigma-70 factor, ECF subfamily
APPACOFM_02868	8.64e-220	-	-	-	PT	-	-	-	Sigma factor regulatory protein, FecR PupR family
APPACOFM_02869	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_02870	1.23e-305	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_02871	0.0	-	-	-	S	-	-	-	Susd and RagB outer membrane lipoprotein
APPACOFM_02872	8.32e-192	-	-	-	G	-	-	-	Putative glycoside hydrolase Family 18, chitinase_18
APPACOFM_02873	7.69e-295	-	-	-	S	-	-	-	Concanavalin A-like lectin/glucanases superfamily
APPACOFM_02874	7.6e-218	-	-	-	S	-	-	-	Domain of unknown function (DUF1735)
APPACOFM_02875	5.2e-178	-	-	-	S	-	-	-	Protein of unknown function (DUF1573)
APPACOFM_02876	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	F5 8 type C domain protein
APPACOFM_02877	1.81e-78	-	-	-	-	-	-	-	-
APPACOFM_02878	2.37e-220	-	-	-	L	-	-	-	Integrase core domain
APPACOFM_02879	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	glycosyl hydrolase, family 3
APPACOFM_02880	1.8e-78	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
APPACOFM_02881	1.95e-220	oxyR	-	-	K	ko:K04761	ko02026,map02026	ko00000,ko00001,ko03000	Psort location Cytoplasmic, score 9.97
APPACOFM_02882	6.53e-220	-	-	-	EG	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_02883	6.59e-151	aqpZ	-	-	G	ko:K06188	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
APPACOFM_02884	8.37e-172	-	-	-	S	-	-	-	COG NOG31568 non supervised orthologous group
APPACOFM_02885	6.34e-127	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
APPACOFM_02886	2.31e-295	-	-	-	K	-	-	-	Outer membrane protein beta-barrel domain
APPACOFM_02887	6.73e-133	-	-	-	K	ko:K03088	-	ko00000,ko03021	ECF sigma factor
APPACOFM_02888	3.19e-239	-	-	-	PT	-	-	-	COG3712 Fe2 -dicitrate sensor, membrane component
APPACOFM_02889	0.0	-	-	-	P	-	-	-	Secretin and TonB N terminus short domain
APPACOFM_02890	0.0	-	-	-	J	ko:K21572	-	ko00000,ko02000	Pfam:SusD
APPACOFM_02891	0.0	-	-	-	C	-	-	-	PKD domain
APPACOFM_02892	6.86e-221	-	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	COG0584 Glycerophosphoryl diester phosphodiesterase
APPACOFM_02893	0.0	-	-	-	G	ko:K07783	ko02020,map02020	ko00000,ko00001,ko02000	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_02894	3.14e-18	-	-	-	-	-	-	-	-
APPACOFM_02895	6.54e-53	-	-	-	-	-	-	-	-
APPACOFM_02897	1.33e-73	-	-	-	S	-	-	-	Phage derived protein Gp49-like (DUF891)
APPACOFM_02898	1.9e-62	-	-	-	K	-	-	-	Helix-turn-helix
APPACOFM_02899	0.0	-	-	-	S	-	-	-	Virulence-associated protein E
APPACOFM_02900	5.12e-42	-	-	-	S	-	-	-	Domain of unknown function (DUF4248)
APPACOFM_02901	9.64e-92	-	-	-	L	-	-	-	DNA-binding protein
APPACOFM_02902	1.76e-24	-	-	-	-	-	-	-	-
APPACOFM_02903	4.55e-113	-	3.5.1.28	-	V	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
APPACOFM_02904	2.32e-179	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
APPACOFM_02905	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 9.97
APPACOFM_02908	1.04e-249	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
APPACOFM_02909	4.47e-113	hndA	1.12.1.3	-	C	ko:K18330	-	ko00000,ko01000	COG COG1905 NADH ubiquinone oxidoreductase 24 kD subunit
APPACOFM_02910	0.0	hndD	1.12.1.3, 1.17.1.9	-	C	ko:K00123,ko:K18332	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	COG COG4624 Iron only hydrogenase large subunit, C-terminal domain
APPACOFM_02911	1.22e-181	nuoF	1.12.1.3, 1.6.5.3	-	C	ko:K00335,ko:K18331	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region
APPACOFM_02913	0.0	-	-	-	S	-	-	-	Heparinase II/III-like protein
APPACOFM_02914	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 28 family
APPACOFM_02915	6.4e-80	-	-	-	-	-	-	-	-
APPACOFM_02916	1.61e-297	uxuA	4.2.1.8	-	H	ko:K01686	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of D-mannonate
APPACOFM_02917	3.98e-190	uxuB_1	-	-	IQ	-	-	-	Oxidoreductase, short chain dehydrogenase reductase family protein
APPACOFM_02918	0.0	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl-hydrolase 97 C-terminal, oligomerisation
APPACOFM_02919	4.31e-145	murQ	4.2.1.126	-	H	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
APPACOFM_02920	2.6e-88	-	-	-	S	-	-	-	Protein of unknown function (DUF3037)
APPACOFM_02921	2.07e-191	-	-	-	DT	-	-	-	aminotransferase class I and II
APPACOFM_02922	0.0	-	-	-	S	-	-	-	Serine hydrolase involved in the detoxification of formaldehyde
APPACOFM_02923	2.74e-66	-	-	-	S	-	-	-	Serine hydrolase involved in the detoxification of formaldehyde
APPACOFM_02924	0.0	-	-	-	D	ko:K09955	-	ko00000	protein conserved in bacteria
APPACOFM_02925	0.0	-	-	-	KT	-	-	-	Two component regulator propeller
APPACOFM_02926	1.35e-118	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
APPACOFM_02928	0.0	-	-	-	H	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_02929	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	COG NOG28394 non supervised orthologous group
APPACOFM_02930	0.0	-	-	-	N	-	-	-	Bacterial group 2 Ig-like protein
APPACOFM_02931	0.0	-	-	-	S	-	-	-	COG NOG07966 non supervised orthologous group
APPACOFM_02932	0.0	xynBA	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 43 family
APPACOFM_02933	3.82e-149	-	3.2.1.180	GH88	S	ko:K18581	-	ko00000,ko01000	Glycosyl Hydrolase Family 88
APPACOFM_02934	2.14e-135	-	3.2.1.180	GH88	S	ko:K18581	-	ko00000,ko01000	Glycosyl Hydrolase Family 88
APPACOFM_02935	8.15e-99	-	-	-	MP	ko:K06079	ko01503,map01503	ko00000,ko00001	COG NOG29769 non supervised orthologous group
APPACOFM_02936	5.58e-290	corC_1	-	-	P	ko:K03699	-	ko00000,ko02042	Psort location CytoplasmicMembrane, score
APPACOFM_02938	2.39e-179	loiP	-	-	M	ko:K07387	-	ko00000,ko01000,ko01002	COG0501 Zn-dependent protease with chaperone function
APPACOFM_02939	0.0	-	-	-	P	-	-	-	Psort location OuterMembrane, score
APPACOFM_02940	7.37e-103	-	-	-	S	-	-	-	COG NOG29214 non supervised orthologous group
APPACOFM_02941	1.46e-197	-	3.1.2.12	CE1	S	ko:K01070	ko00680,ko01120,ko01200,map00680,map01120,map01200	ko00000,ko00001,ko01000	esterase
APPACOFM_02942	1.58e-206	-	-	-	S	-	-	-	COG NOG30864 non supervised orthologous group
APPACOFM_02943	0.0	-	-	-	M	-	-	-	peptidase S41
APPACOFM_02944	1.78e-265	trmU	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
APPACOFM_02945	2.69e-149	narL	-	-	K	-	-	-	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
APPACOFM_02946	2.57e-102	-	-	-	S	-	-	-	COG NOG27363 non supervised orthologous group
APPACOFM_02947	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_02948	1.21e-189	-	-	-	S	-	-	-	VIT family
APPACOFM_02949	4.11e-100	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.46
APPACOFM_02950	2.59e-276	ynfM	-	-	EGP	ko:K08224	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_02951	0.0	pbpC	2.4.1.129	GT51	M	ko:K05367	ko00550,map00550	ko00000,ko00001,ko01000,ko01003,ko01011	COG4953 Membrane carboxypeptidase penicillin-binding protein PbpC
APPACOFM_02952	4.92e-76	pbpC	2.4.1.129	GT51	M	ko:K05367	ko00550,map00550	ko00000,ko00001,ko01000,ko01003,ko01011	COG4953 Membrane carboxypeptidase penicillin-binding protein PbpC
APPACOFM_02953	0.0	-	-	-	S	ko:K06894	-	ko00000	COG2373 Large extracellular alpha-helical protein
APPACOFM_02954	1.6e-94	mip	5.2.1.8	-	O	ko:K01802	-	ko00000,ko01000	COG COG0545 FKBP-type peptidyl-prolyl cis-trans isomerases 1
APPACOFM_02955	2.02e-27	-	-	-	CO	-	-	-	Redoxin
APPACOFM_02956	1.69e-92	-	-	-	CO	-	-	-	Redoxin
APPACOFM_02957	1.32e-74	-	-	-	S	-	-	-	Protein of unknown function DUF86
APPACOFM_02958	3.23e-66	-	-	-	S	ko:K07075	-	ko00000	Nucleotidyltransferase domain
APPACOFM_02959	4.73e-270	-	-	-	L	-	-	-	COG NOG19081 non supervised orthologous group
APPACOFM_02960	3.42e-68	-	-	-	S	-	-	-	Protein of unknown function (DUF1622)
APPACOFM_02961	0.0	-	-	-	G	-	-	-	COG NOG27433 non supervised orthologous group
APPACOFM_02962	3e-80	-	-	-	-	-	-	-	-
APPACOFM_02963	5.76e-243	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_02964	8.08e-171	-	-	-	C	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_02965	1.79e-96	-	-	-	-	-	-	-	-
APPACOFM_02966	1.44e-113	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_02967	5.84e-183	-	-	-	S	-	-	-	COG NOG34011 non supervised orthologous group
APPACOFM_02968	9.36e-124	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
APPACOFM_02969	7.84e-101	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
APPACOFM_02970	0.0	metH	2.1.1.13	-	E	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
APPACOFM_02971	7.57e-141	-	-	-	C	-	-	-	COG0778 Nitroreductase
APPACOFM_02972	2.44e-25	-	-	-	-	-	-	-	-
APPACOFM_02973	7.25e-239	-	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
APPACOFM_02974	2.31e-147	mltF	-	-	M	ko:K18691	-	ko00000,ko01000,ko01011	soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein
APPACOFM_02975	1.8e-177	mltF	-	-	M	ko:K18691	-	ko00000,ko01000,ko01011	soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein
APPACOFM_02976	3.19e-145	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
APPACOFM_02977	2.43e-64	-	-	-	S	-	-	-	Stress responsive A B barrel domain protein
APPACOFM_02978	0.0	dsbD	1.8.1.8	-	CO	ko:K04084	-	ko00000,ko01000,ko03110	cytochrome c biogenesis protein transmembrane region
APPACOFM_02979	1.4e-176	-	-	-	S	ko:K06911	-	ko00000	Belongs to the pirin family
APPACOFM_02980	2.52e-135	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70, region 4
APPACOFM_02981	1.01e-225	-	-	-	PT	-	-	-	Domain of unknown function (DUF4974)
APPACOFM_02982	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_02983	0.0	-	-	-	GM	ko:K21572	-	ko00000,ko02000	Pfam:SusD
APPACOFM_02984	0.0	-	-	-	S	-	-	-	Fibronectin type III domain
APPACOFM_02985	4.59e-216	-	-	-	M	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_02986	4.91e-268	-	-	-	S	-	-	-	Beta-lactamase superfamily domain
APPACOFM_02987	3.31e-204	glpQ1_1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.96
APPACOFM_02988	0.0	-	-	-	G	ko:K07783	ko02020,map02020	ko00000,ko00001,ko02000	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_02989	2.08e-145	-	-	-	S	-	-	-	Protein of unknown function (DUF2490)
APPACOFM_02990	0.0	-	-	-	S	-	-	-	Fibrobacter succinogenes major domain (Fib_succ_major)
APPACOFM_02991	5.38e-121	-	-	-	Q	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_02992	1.62e-195	hisG	2.4.2.17	-	F	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	ATP phosphoribosyltransferase
APPACOFM_02993	2.92e-296	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
APPACOFM_02994	5.64e-255	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
APPACOFM_02995	5.24e-281	hisB	3.1.3.15, 4.2.1.19	-	E	ko:K01089,ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidine biosynthesis bifunctional protein HisB
APPACOFM_02996	3.85e-117	-	-	-	T	-	-	-	Tyrosine phosphatase family
APPACOFM_02997	8.27e-279	nadE	6.3.5.1	-	H	ko:K01950	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
APPACOFM_02998	2.3e-153	nadE	6.3.5.1	-	H	ko:K01950	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
APPACOFM_02999	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_03000	0.0	-	-	-	K	-	-	-	Pfam:SusD
APPACOFM_03001	8.54e-215	-	-	-	S	-	-	-	Domain of unknown function (DUF4984)
APPACOFM_03002	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF5003)
APPACOFM_03003	0.0	-	-	-	S	-	-	-	leucine rich repeat protein
APPACOFM_03004	0.0	-	-	-	S	-	-	-	Putative binding domain, N-terminal
APPACOFM_03005	0.0	-	-	-	O	-	-	-	Psort location Extracellular, score
APPACOFM_03006	1.57e-196	-	-	-	S	-	-	-	Protein of unknown function (DUF1573)
APPACOFM_03007	6.6e-115	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_03008	3.67e-102	fur	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
APPACOFM_03009	2.58e-137	rbr3A	-	-	C	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_03010	1.95e-135	-	-	-	C	-	-	-	Nitroreductase family
APPACOFM_03011	3.57e-108	-	-	-	O	-	-	-	Thioredoxin
APPACOFM_03012	5.28e-68	-	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Psort location Cytoplasmic, score
APPACOFM_03013	3.02e-276	-	-	-	M	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_03014	3.69e-37	-	-	-	-	-	-	-	-
APPACOFM_03016	0.0	-	-	-	S	-	-	-	COG NOG06390 non supervised orthologous group
APPACOFM_03017	0.0	dpp11	-	-	E	-	-	-	COG NOG04781 non supervised orthologous group
APPACOFM_03018	0.0	atsB	-	-	C	ko:K06871	-	ko00000	COG0641 Arylsulfatase regulator (Fe-S oxidoreductase)
APPACOFM_03019	1.55e-169	-	-	-	S	-	-	-	COG NOG27017 non supervised orthologous group
APPACOFM_03020	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat protein
APPACOFM_03021	2.6e-79	-	-	-	S	-	-	-	Domain of unknown function (DUF3244)
APPACOFM_03022	3.02e-111	-	-	-	CG	-	-	-	glycosyl
APPACOFM_03023	9.9e-202	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
APPACOFM_03024	1.76e-298	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
APPACOFM_03025	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	COG0419 ATPase involved in DNA repair
APPACOFM_03026	1.4e-115	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	COG0419 ATPase involved in DNA repair
APPACOFM_03027	7.56e-288	-	-	-	S	ko:K07098	-	ko00000	Ser Thr phosphatase family protein
APPACOFM_03028	7.85e-126	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
APPACOFM_03029	2.74e-117	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
APPACOFM_03030	1.09e-222	metH_2	-	-	E	-	-	-	Vitamin B12 dependent methionine synthase, activation domain
APPACOFM_03031	0.0	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
APPACOFM_03032	3.6e-72	dpm1	2.4.1.83	GT2	S	ko:K00721	ko00510,ko01100,map00510,map01100	ko00000,ko00001,ko01000,ko01003	b-glycosyltransferase, glycosyltransferase family 2 protein
APPACOFM_03033	3e-85	dpm1	2.4.1.83	GT2	S	ko:K00721	ko00510,ko01100,map00510,map01100	ko00000,ko00001,ko01000,ko01003	b-glycosyltransferase, glycosyltransferase family 2 protein
APPACOFM_03034	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
APPACOFM_03035	2.34e-203	-	-	-	-	-	-	-	-
APPACOFM_03036	0.0	-	-	-	C	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_03037	4.08e-47	-	-	-	O	-	-	-	Belongs to the sulfur carrier protein TusA family
APPACOFM_03038	5.77e-68	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_03039	0.0	xly	-	-	M	-	-	-	fibronectin type III domain protein
APPACOFM_03040	0.0	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.96
APPACOFM_03041	1.2e-195	ramA_1	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	hydrolase, carbon-nitrogen family
APPACOFM_03042	1.05e-135	-	-	-	I	-	-	-	Acyltransferase
APPACOFM_03043	8.63e-58	-	-	-	S	-	-	-	COG NOG23371 non supervised orthologous group
APPACOFM_03044	0.0	-	-	-	-	-	-	-	-
APPACOFM_03045	0.0	-	-	-	M	-	-	-	Glycosyl hydrolases family 43
APPACOFM_03046	0.0	-	-	-	G	-	-	-	Ricin-type beta-trefoil lectin domain-like
APPACOFM_03047	0.0	-	-	-	-	-	-	-	-
APPACOFM_03048	0.0	-	-	-	T	-	-	-	cheY-homologous receiver domain
APPACOFM_03049	0.0	-	-	-	P	-	-	-	TonB-dependent Receptor Plug Domain
APPACOFM_03050	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	Pfam:SusD
APPACOFM_03051	1.98e-191	-	-	-	M	-	-	-	COG2335, Secreted and surface protein containing fasciclin-like repeats
APPACOFM_03052	5.47e-243	-	-	-	S	-	-	-	Domain of unknown function (DUF5007)
APPACOFM_03053	8.51e-293	-	-	-	P	-	-	-	Carboxypeptidase regulatory-like domain
APPACOFM_03054	0.0	-	-	-	P	-	-	-	Carboxypeptidase regulatory-like domain
APPACOFM_03055	0.0	-	-	-	GM	ko:K21572	-	ko00000,ko02000	SusD family
APPACOFM_03056	4.01e-179	-	-	-	S	-	-	-	Fasciclin domain
APPACOFM_03057	0.0	-	-	-	G	-	-	-	Domain of unknown function (DUF5124)
APPACOFM_03058	0.0	-	-	-	S	-	-	-	Concanavalin A-like lectin/glucanases superfamily
APPACOFM_03059	0.0	-	-	-	S	-	-	-	N-terminal domain of M60-like peptidases
APPACOFM_03060	0.0	-	-	-	S	-	-	-	Type I phosphodiesterase / nucleotide pyrophosphatase
APPACOFM_03061	3.69e-180	-	-	-	-	-	-	-	-
APPACOFM_03062	5.71e-152	-	-	-	L	-	-	-	regulation of translation
APPACOFM_03063	2.41e-315	-	-	-	S	-	-	-	P-loop ATPase and inactivated derivatives
APPACOFM_03064	1.42e-262	-	-	-	S	-	-	-	Leucine rich repeat protein
APPACOFM_03065	0.0	-	-	-	U	ko:K03561	-	ko00000,ko02000	MotA/TolQ/ExbB proton channel family
APPACOFM_03066	1.94e-100	-	-	-	U	ko:K03559	-	ko00000,ko02000	Biopolymer transport protein ExbD/TolR
APPACOFM_03067	1.33e-99	-	-	-	U	ko:K03559	-	ko00000,ko02000	Biopolymer transport protein ExbD/TolR
APPACOFM_03068	0.0	-	-	-	-	-	-	-	-
APPACOFM_03069	0.0	-	-	-	H	-	-	-	Psort location OuterMembrane, score
APPACOFM_03070	2.74e-200	-	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 35 family
APPACOFM_03071	0.0	-	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 35 family
APPACOFM_03072	1.92e-71	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
APPACOFM_03073	5.16e-89	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
APPACOFM_03074	1.91e-186	-	-	-	S	-	-	-	Exopolysaccharide biosynthesis protein YbjH
APPACOFM_03075	7.44e-297	-	-	-	-	-	-	-	-
APPACOFM_03076	1.14e-315	-	-	-	S	-	-	-	COG NOG33609 non supervised orthologous group
APPACOFM_03077	5.37e-217	-	-	-	V	-	-	-	AAA domain, putative AbiEii toxin, Type IV TA system
APPACOFM_03078	0.0	-	-	-	S	-	-	-	ABC-type transport system involved in multi-copper enzyme maturation permease component
APPACOFM_03079	0.0	-	-	-	MU	-	-	-	Outer membrane efflux protein
APPACOFM_03080	1.42e-247	-	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Barrel-sandwich domain of CusB or HlyD membrane-fusion
APPACOFM_03081	0.0	-	-	-	V	ko:K03296	-	ko00000	AcrB/AcrD/AcrF family
APPACOFM_03082	1.13e-50	-	-	-	V	-	-	-	AcrB/AcrD/AcrF family
APPACOFM_03083	0.0	-	-	-	V	-	-	-	AcrB/AcrD/AcrF family
APPACOFM_03084	1.27e-158	-	-	-	-	-	-	-	-
APPACOFM_03085	0.0	-	-	-	M	ko:K07001	-	ko00000	Phospholipase, patatin family
APPACOFM_03086	5.11e-284	-	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
APPACOFM_03087	0.0	-	-	-	V	-	-	-	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
APPACOFM_03088	0.0	-	-	-	M	ko:K18139,ko:K18300	ko01501,ko02024,map01501,map02024	ko00000,ko00001,ko00002,ko01504,ko02000	Efflux transporter, outer membrane factor lipoprotein, NodT family
APPACOFM_03089	0.0	pfp	2.7.1.11, 2.7.1.90	-	H	ko:K00895,ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions
APPACOFM_03090	7.53e-208	acm	-	-	M	ko:K07273	-	ko00000	phage tail component domain protein
APPACOFM_03091	0.0	lpdA	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dihydrolipoyl dehydrogenase
APPACOFM_03092	4.86e-175	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
APPACOFM_03093	4e-313	bfmBB	2.3.1.61	-	C	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 9.26
APPACOFM_03094	0.0	bfmBAB	1.2.4.4	-	C	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	dehydrogenase E1 component
APPACOFM_03095	3.07e-124	isiB	-	-	C	ko:K03839	-	ko00000	Low-potential electron donor to a number of redox enzymes
APPACOFM_03096	7.01e-209	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Methylates ribosomal protein L11
APPACOFM_03097	2.25e-117	-	-	-	S	-	-	-	Psort location OuterMembrane, score
APPACOFM_03098	0.0	-	-	-	I	-	-	-	Psort location OuterMembrane, score
APPACOFM_03099	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_03100	0.0	-	-	-	H	-	-	-	Susd and RagB outer membrane lipoprotein
APPACOFM_03101	4.66e-135	-	-	-	-	-	-	-	-
APPACOFM_03102	4.25e-104	guaD	3.5.4.3	-	FJ	ko:K01487	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Cytidine and deoxycytidylate deaminase zinc-binding region
APPACOFM_03103	3.35e-247	-	-	-	S	-	-	-	Oxidoreductase, NAD-binding domain protein
APPACOFM_03104	4.63e-224	-	-	-	-	-	-	-	-
APPACOFM_03105	6.72e-97	-	-	-	-	-	-	-	-
APPACOFM_03106	4.17e-102	-	-	-	C	-	-	-	lyase activity
APPACOFM_03107	7.19e-115	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
APPACOFM_03108	1.77e-197	-	-	-	ET	-	-	-	COG0834 ABC-type amino acid transport signal transduction systems periplasmic component domain
APPACOFM_03109	0.0	-	-	-	H	-	-	-	COG NOG07963 non supervised orthologous group
APPACOFM_03110	1.82e-125	porG	1.2.7.3	-	C	ko:K00177	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	br01601,ko00000,ko00001,ko00002,ko01000	2-oxoacid ferredoxin flavodoxin oxidoreductase, gamma subunit
APPACOFM_03111	3.43e-187	vorA	1.2.7.11, 1.2.7.3	-	C	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain
APPACOFM_03112	1.44e-31	-	-	-	-	-	-	-	-
APPACOFM_03113	1.09e-250	vorB	1.2.7.11, 1.2.7.3	-	C	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	COG0674 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin
APPACOFM_03114	3.12e-38	oorD	1.2.7.3	-	C	ko:K00176	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	br01601,ko00000,ko00001,ko00002,ko01000	4Fe-4S binding domain protein
APPACOFM_03115	1.77e-61	-	-	-	S	-	-	-	TPR repeat
APPACOFM_03116	0.0	ravA_1	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
APPACOFM_03117	3.36e-90	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_03118	2.92e-217	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_03119	2.96e-94	-	-	-	S	ko:K09793	-	ko00000	Psort location CytoplasmicMembrane, score 9.46
APPACOFM_03120	0.0	-	-	-	P	-	-	-	Right handed beta helix region
APPACOFM_03121	0.0	-	3.2.1.177	GH31	G	ko:K01811	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 31 family
APPACOFM_03122	8.91e-262	-	-	-	E	-	-	-	B12 binding domain
APPACOFM_03123	7.73e-172	-	-	-	E	-	-	-	B12 binding domain
APPACOFM_03124	0.0	-	-	-	S	ko:K03307	-	ko00000	Sodium:solute symporter family
APPACOFM_03125	1.39e-183	-	-	-	E	-	-	-	Vitamin B12 dependent methionine synthase, activation domain protein
APPACOFM_03126	6.73e-243	-	4.1.1.37	-	H	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen decarboxylase (URO-D)
APPACOFM_03127	1.64e-203	-	-	-	-	-	-	-	-
APPACOFM_03128	7.17e-171	-	-	-	-	-	-	-	-
APPACOFM_03129	9.32e-106	rpiB	5.3.1.6	-	G	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase
APPACOFM_03130	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the transketolase family
APPACOFM_03131	0.0	abf2	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	Alpha-L-arabinofuranosidase domain protein
APPACOFM_03132	0.0	-	-	-	D	ko:K09955	-	ko00000	protein conserved in bacteria
APPACOFM_03133	0.0	araB	-	-	G	-	-	-	Carbohydrate kinase, FGGY family protein
APPACOFM_03134	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
APPACOFM_03135	1.99e-168	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
APPACOFM_03136	3.04e-162	-	-	-	F	-	-	-	Hydrolase, NUDIX family
APPACOFM_03137	0.0	-	-	-	S	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
APPACOFM_03138	2.28e-147	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Converts alpha-aldose to the beta-anomer
APPACOFM_03139	2.01e-92	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Converts alpha-aldose to the beta-anomer
APPACOFM_03140	2.41e-84	-	-	-	L	ko:K07483	-	ko00000	COG2963 Transposase and inactivated derivatives
APPACOFM_03141	1.77e-177	-	-	-	L	-	-	-	Integrase core domain
APPACOFM_03142	0.0	-	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Glycosyl hydrolases family 43
APPACOFM_03143	0.0	-	-	-	F	ko:K21572	-	ko00000,ko02000	Pfam:SusD
APPACOFM_03144	0.0	-	-	-	P	-	-	-	TonB-dependent Receptor Plug Domain
APPACOFM_03145	0.0	-	-	-	F	ko:K21572	-	ko00000,ko02000	Pfam:SusD
APPACOFM_03146	0.0	-	-	-	H	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_03147	0.0	-	-	-	-	-	-	-	-
APPACOFM_03148	0.0	-	-	-	T	-	-	-	adenylate cyclase carring two-component hybrid sensor and regulator domains
APPACOFM_03149	0.0	-	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
APPACOFM_03150	0.0	-	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	Carbohydrate binding domain protein
APPACOFM_03151	2.81e-223	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 43 family
APPACOFM_03152	1.52e-285	galK	2.7.1.6	-	H	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GHMP kinase family. GalK subfamily
APPACOFM_03153	3.49e-306	gluP	-	-	G	ko:K02429	-	ko00000,ko02000	Transporter, major facilitator family protein
APPACOFM_03154	3.79e-274	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Converts alpha-aldose to the beta-anomer
APPACOFM_03155	1.84e-237	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.96
APPACOFM_03156	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_03157	1.83e-152	-	-	-	L	-	-	-	Phage integrase family
APPACOFM_03158	1.17e-136	-	-	-	K	-	-	-	KOW (Kyprides, Ouzounis, Woese) motif.
APPACOFM_03159	1.13e-59	-	-	-	S	-	-	-	UpxZ family of transcription anti-terminator antagonists
APPACOFM_03160	0.0	wbpM	-	-	GM	-	-	-	Polysaccharide biosynthesis protein
APPACOFM_03161	1.8e-289	ugd	1.1.1.22	-	C	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
APPACOFM_03164	7.04e-223	-	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	UDP-N-acetylglucosamine 2-epimerase
APPACOFM_03165	6.86e-43	-	-	-	M	-	-	-	Polysaccharide pyruvyl transferase
APPACOFM_03166	9.2e-57	-	-	-	C	-	-	-	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term
APPACOFM_03167	3.57e-137	-	-	-	S	-	-	-	polysaccharide biosynthetic process
APPACOFM_03168	2.31e-92	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
APPACOFM_03170	1.81e-128	-	-	-	M	-	-	-	Glycosyl transferases group 1
APPACOFM_03171	7.06e-37	wcfG	-	-	M	-	-	-	PFAM Glycosyl transferases group 1
APPACOFM_03172	7.4e-44	wcfG	-	-	M	-	-	-	PFAM Glycosyl transferase, group 1
APPACOFM_03173	2.78e-53	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
APPACOFM_03174	3.89e-134	-	-	-	M	-	-	-	Glycosyltransferase like family 2
APPACOFM_03175	1.93e-159	-	-	-	S	-	-	-	Polysaccharide pyruvyl transferase
APPACOFM_03176	2.36e-144	-	-	-	C	-	-	-	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term
APPACOFM_03177	1.28e-125	-	-	-	M	-	-	-	Bacterial sugar transferase
APPACOFM_03178	1.97e-277	pglE	-	-	E	-	-	-	Belongs to the DegT DnrJ EryC1 family
APPACOFM_03179	2.37e-253	gmd	4.2.1.47	-	M	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
APPACOFM_03180	1.01e-254	fcl	1.1.1.271	-	GM	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction
APPACOFM_03181	2.99e-176	-	-	-	M	ko:K01991	ko02026,map02026	ko00000,ko00001,ko02000	COG1596 Periplasmic protein involved in polysaccharide export
APPACOFM_03182	0.0	-	-	-	DM	-	-	-	Chain length determinant protein
APPACOFM_03183	2.06e-46	-	-	-	S	-	-	-	Domain of unknown function (DUF4248)
APPACOFM_03184	5.15e-100	-	3.5.1.28	-	V	ko:K01447	-	ko00000,ko01000	Psort location Cytoplasmic, score 8.96
APPACOFM_03186	6.25e-112	-	-	-	L	-	-	-	regulation of translation
APPACOFM_03187	0.0	-	-	-	L	-	-	-	Protein of unknown function (DUF3987)
APPACOFM_03188	2.2e-83	-	-	-	-	-	-	-	-
APPACOFM_03189	2.27e-49	-	-	-	S	-	-	-	COG NOG35393 non supervised orthologous group
APPACOFM_03190	5.68e-52	-	-	-	S	-	-	-	COG NOG30994 non supervised orthologous group
APPACOFM_03191	8.36e-38	-	-	-	S	-	-	-	COG NOG35214 non supervised orthologous group
APPACOFM_03192	2.39e-179	ydfG	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
APPACOFM_03193	2.12e-89	-	-	-	D	-	-	-	Sporulation and cell division repeat protein
APPACOFM_03194	3.84e-191	cysQ	3.1.3.7	-	P	ko:K01082	ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130	ko00000,ko00001,ko01000,ko03016	3'(2'),5'-bisphosphate nucleotidase
APPACOFM_03195	0.0	-	-	-	P	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_03196	4.9e-138	cysC	2.7.1.25	-	F	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
APPACOFM_03197	5.86e-222	cysD	2.7.7.4	-	H	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase) FAD synthetase
APPACOFM_03198	0.0	cysN	2.7.1.25, 2.7.7.4	-	H	ko:K00955,ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily
APPACOFM_03199	9e-279	-	-	-	S	-	-	-	Sulfotransferase family
APPACOFM_03200	1.58e-216	-	-	-	S	-	-	-	COG NOG26583 non supervised orthologous group
APPACOFM_03201	2.22e-272	-	-	-	M	-	-	-	Psort location OuterMembrane, score
APPACOFM_03202	1.29e-91	ruvX	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
APPACOFM_03203	3.81e-129	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
APPACOFM_03204	1.17e-200	-	-	-	S	-	-	-	COG COG0457 FOG TPR repeat
APPACOFM_03205	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
APPACOFM_03206	7.48e-133	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
APPACOFM_03208	6.17e-75	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
APPACOFM_03209	1.16e-195	-	-	-	C	-	-	-	4Fe-4S binding domain protein
APPACOFM_03210	1.17e-107	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
APPACOFM_03211	4.79e-143	paaK	6.2.1.30	-	H	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	ko00000,ko00001,ko01000	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
APPACOFM_03212	1.33e-145	paaK	6.2.1.30	-	H	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	ko00000,ko00001,ko01000	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
APPACOFM_03213	8.86e-133	iorB	1.2.7.8	-	C	ko:K00180	-	br01601,ko00000,ko01000	COG1014 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin
APPACOFM_03214	0.0	iorA	1.2.7.8	-	C	ko:K00179	-	br01601,ko00000,ko01000	Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates
APPACOFM_03215	7.72e-257	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
APPACOFM_03216	1.22e-215	nucA_1	-	-	F	ko:K01173	ko04210,map04210	ko00000,ko00001,ko03029	Psort location Extracellular, score
APPACOFM_03218	2.46e-291	nagC	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
APPACOFM_03219	0.0	-	-	-	O	-	-	-	FAD dependent oxidoreductase
APPACOFM_03220	5.41e-279	-	-	-	S	-	-	-	Domain of unknown function (DUF5109)
APPACOFM_03221	0.0	araE	-	-	P	ko:K08138,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
APPACOFM_03222	8.66e-89	ce	5.1.3.8	-	G	ko:K01787	ko00520,map00520	ko00000,ko00001,ko01000	COG COG2942 N-acyl-D-glucosamine 2-epimerase
APPACOFM_03223	3.98e-213	ce	5.1.3.8	-	G	ko:K01787	ko00520,map00520	ko00000,ko00001,ko01000	COG COG2942 N-acyl-D-glucosamine 2-epimerase
APPACOFM_03224	0.0	-	3.2.1.50	-	G	ko:K01205	ko00531,ko01100,ko04142,map00531,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko04147	Alpha-N-acetylglucosaminidase
APPACOFM_03225	0.0	-	-	-	H	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_03226	0.0	-	-	-	P	ko:K21572	-	ko00000,ko02000	SusD family
APPACOFM_03227	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF1735)
APPACOFM_03228	7.11e-68	-	-	-	C	-	-	-	Domain of unknown function (DUF4855)
APPACOFM_03229	0.0	-	-	-	C	-	-	-	Domain of unknown function (DUF4855)
APPACOFM_03231	2.35e-67	bglB	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 3 family
APPACOFM_03232	1.6e-311	-	-	-	-	-	-	-	-
APPACOFM_03233	7.38e-277	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
APPACOFM_03234	5.06e-314	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_03235	0.0	-	3.1.1.53	-	G	ko:K05970	-	ko00000,ko01000	COG NOG04984 non supervised orthologous group
APPACOFM_03236	0.0	-	-	-	S	-	-	-	C terminal of Calcineurin-like phosphoesterase
APPACOFM_03237	0.0	-	-	-	S	-	-	-	Domain of unknown function
APPACOFM_03238	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF5018)
APPACOFM_03239	0.0	-	-	-	F	ko:K21572	-	ko00000,ko02000	SusD family
APPACOFM_03240	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_03241	1.1e-92	ce	5.1.3.8	-	G	ko:K01787	ko00520,map00520	ko00000,ko00001,ko01000	COG COG2942 N-acyl-D-glucosamine 2-epimerase
APPACOFM_03242	2.67e-30	ce	5.1.3.8	-	G	ko:K01787	ko00520,map00520	ko00000,ko00001,ko01000	COG COG2942 N-acyl-D-glucosamine 2-epimerase
APPACOFM_03243	2.18e-161	ce	5.1.3.8	-	G	ko:K01787	ko00520,map00520	ko00000,ko00001,ko01000	COG COG2942 N-acyl-D-glucosamine 2-epimerase
APPACOFM_03244	1.58e-93	araE	-	-	P	ko:K08138,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
APPACOFM_03245	1.43e-103	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
APPACOFM_03247	2.42e-228	-	-	-	E	-	-	-	COG NOG09493 non supervised orthologous group
APPACOFM_03248	1.64e-227	-	-	-	G	-	-	-	Phosphodiester glycosidase
APPACOFM_03249	1.65e-304	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_03250	8.18e-275	-	3.1.1.53	-	G	ko:K05970	-	ko00000,ko01000	COG NOG04984 non supervised orthologous group
APPACOFM_03251	0.0	-	-	-	S	-	-	-	C terminal of Calcineurin-like phosphoesterase
APPACOFM_03252	4.23e-305	-	3.1.1.53	-	G	ko:K05970	-	ko00000,ko01000	COG NOG04984 non supervised orthologous group
APPACOFM_03253	2.33e-312	-	-	-	S	-	-	-	Domain of unknown function
APPACOFM_03254	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF5018)
APPACOFM_03255	0.0	-	-	-	F	ko:K21572	-	ko00000,ko02000	SusD family
APPACOFM_03256	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_03257	4.55e-198	-	-	-	S	-	-	-	Domain of unknown function (DUF5109)
APPACOFM_03258	3.19e-49	-	-	-	S	-	-	-	Domain of unknown function (DUF5109)
APPACOFM_03259	3e-298	ce	5.1.3.8	-	G	ko:K01787	ko00520,map00520	ko00000,ko00001,ko01000	COG COG2942 N-acyl-D-glucosamine 2-epimerase
APPACOFM_03260	1.27e-92	araE	-	-	P	ko:K08138,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
APPACOFM_03261	0.0	nanH	3.2.1.18	GH33	G	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	ko00000,ko00001,ko01000,ko02042	BNR Asp-box repeat protein
APPACOFM_03262	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 20, catalytic domain
APPACOFM_03263	0.0	estS	3.1.1.53	-	E	ko:K05970	-	ko00000,ko01000	Carbohydrate esterase, sialic acid-specific acetylesterase
APPACOFM_03264	0.0	-	3.2.1.25	-	G	ko:K01192	ko00511,ko04142,map00511,map04142	ko00000,ko00001,ko01000	Glycosyl hydrolase family 2, sugar binding domain protein
APPACOFM_03265	1.31e-223	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycosyl hydrolase family 20, catalytic domain protein
APPACOFM_03266	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycosyl hydrolase family 20, catalytic domain protein
APPACOFM_03267	0.0	nagZ3	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycosyl hydrolase family 20, catalytic domain
APPACOFM_03268	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
APPACOFM_03269	1.28e-136	-	-	-	K	-	-	-	Transcription termination antitermination factor NusG
APPACOFM_03270	2.85e-211	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
APPACOFM_03271	3.25e-137	rfbC	5.1.3.13	-	G	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
APPACOFM_03272	6.52e-212	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
APPACOFM_03273	2.69e-281	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
APPACOFM_03274	0.0	-	-	-	V	-	-	-	COG NOG25117 non supervised orthologous group
APPACOFM_03275	2.99e-294	-	-	-	C	-	-	-	coenzyme F420-reducing hydrogenase beta subunit
APPACOFM_03276	3.02e-247	-	-	-	-	-	-	-	-
APPACOFM_03277	8.85e-309	-	-	-	S	-	-	-	Polysaccharide pyruvyl transferase
APPACOFM_03278	2.23e-76	-	-	-	M	-	-	-	Glycosyl transferases group 1
APPACOFM_03279	6.6e-196	-	-	-	M	-	-	-	Glycosyl transferases group 1
APPACOFM_03280	1.29e-181	-	-	-	M	-	-	-	Bacterial transferase hexapeptide (six repeats)
APPACOFM_03281	1.57e-233	-	-	-	M	-	-	-	Glycosyl transferase family 2
APPACOFM_03282	2.03e-249	-	2.7.1.168	-	S	ko:K07031	ko00540,map00540	ko00000,ko00001,ko01000	GHMP kinases C terminal
APPACOFM_03283	4.05e-135	gmhA	5.3.1.28	-	G	ko:K03271	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate
APPACOFM_03284	3.05e-176	gmhB	2.7.7.71	-	JM	ko:K15669	ko00540,map00540	ko00000,ko00001,ko01000	Nucleotidyl transferase
APPACOFM_03285	1.56e-112	gmhB	3.1.3.82, 3.1.3.83	-	E	ko:K03273	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Polynucleotide kinase 3 phosphatase
APPACOFM_03286	5.83e-275	-	-	-	M	-	-	-	Glycosyl transferases group 1
APPACOFM_03287	7.53e-201	-	-	-	M	ko:K07011	-	ko00000	Glycosyltransferase like family 2
APPACOFM_03288	0.0	-	2.7.8.6	-	M	ko:K00996,ko:K03606	ko05111,map05111	ko00000,ko00001,ko01000,ko01005	Psort location CytoplasmicMembrane, score
APPACOFM_03289	6.56e-182	-	-	-	M	ko:K01991	ko02026,map02026	ko00000,ko00001,ko02000	COG1596 Periplasmic protein involved in polysaccharide export
APPACOFM_03290	0.0	-	-	-	DM	-	-	-	Chain length determinant protein
APPACOFM_03291	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_03292	0.0	-	-	-	M	ko:K21572	-	ko00000,ko02000	SusD family
APPACOFM_03293	3e-35	-	-	-	N	-	-	-	HicA toxin of bacterial toxin-antitoxin,
APPACOFM_03294	1.01e-82	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_03295	7.51e-221	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
APPACOFM_03296	2.33e-123	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
APPACOFM_03297	0.0	-	-	-	S	-	-	-	COG COG0488 ATPase components of ABC transporters with duplicated ATPase domains
APPACOFM_03299	3.25e-251	-	-	-	S	-	-	-	COG NOG26673 non supervised orthologous group
APPACOFM_03300	2.54e-211	-	-	-	S	ko:K07052	-	ko00000	CAAX amino terminal protease family protein
APPACOFM_03301	0.0	yhgF	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain
APPACOFM_03302	4.8e-291	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
APPACOFM_03303	1.52e-159	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
APPACOFM_03304	0.0	cpdB	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
APPACOFM_03305	8.49e-211	-	-	-	K	-	-	-	methylphosphotriester-DNA alkyltransferase and transcriptional regulator (AraC XylS family)
APPACOFM_03306	4.57e-135	-	-	-	T	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_03307	1.5e-176	-	-	-	S	-	-	-	Domain of Unknown Function with PDB structure
APPACOFM_03308	1.44e-42	-	-	-	-	-	-	-	-
APPACOFM_03312	7.04e-107	-	-	-	-	-	-	-	-
APPACOFM_03313	0.0	-	-	-	P	ko:K07085	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_03314	0.0	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3
APPACOFM_03315	3.03e-154	-	-	-	S	-	-	-	Peptidase C14 caspase catalytic subunit p20
APPACOFM_03316	0.0	-	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	Psort location CytoplasmicMembrane, score
APPACOFM_03317	1.41e-269	fcl	1.1.1.271	-	GM	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction
APPACOFM_03318	1.4e-260	gmd	4.2.1.47	-	M	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
APPACOFM_03319	2.89e-256	sstT	-	-	U	-	-	-	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
APPACOFM_03320	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
APPACOFM_03321	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
APPACOFM_03322	2.64e-165	pgl	3.1.1.31	-	G	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	COG0363 6-phosphogluconolactonase Glucosamine-6-phosphate isomerase deaminase
APPACOFM_03323	2.41e-234	yfeX	-	-	P	ko:K07223	-	ko00000	Dyp-type peroxidase family
APPACOFM_03324	2.14e-170	yoqW	-	-	E	-	-	-	SOS response associated peptidase (SRAP)
APPACOFM_03325	5.22e-162	-	-	-	K	-	-	-	COG3279 Response regulator of the LytR AlgR family
APPACOFM_03326	2.06e-258	cheA	-	-	T	-	-	-	two-component sensor histidine kinase
APPACOFM_03327	6.4e-280	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Efflux ABC transporter, permease protein
APPACOFM_03328	6.82e-170	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
APPACOFM_03329	5.57e-271	-	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
APPACOFM_03330	2.02e-308	-	-	-	MU	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	type I secretion outer membrane protein, TolC family
APPACOFM_03332	8.29e-51	-	-	-	S	-	-	-	COG NOG17489 non supervised orthologous group
APPACOFM_03333	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG1271 Cytochrome bd-type quinol oxidase, subunit 1
APPACOFM_03334	9.27e-130	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG1294 Cytochrome bd-type quinol oxidase subunit 2
APPACOFM_03335	2.78e-127	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG1294 Cytochrome bd-type quinol oxidase subunit 2
APPACOFM_03337	2.7e-232	hprA	1.1.1.29	-	C	ko:K00018	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
APPACOFM_03338	6.2e-302	rarA	-	-	L	ko:K07478	-	ko00000	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
APPACOFM_03339	0.0	-	-	-	M	-	-	-	COG NOG06397 non supervised orthologous group
APPACOFM_03341	2.37e-220	-	-	-	L	-	-	-	Integrase core domain
APPACOFM_03342	1.81e-78	-	-	-	-	-	-	-	-
APPACOFM_03343	1.3e-69	wecB	5.1.3.14	-	M	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
APPACOFM_03344	2.03e-152	wecB	5.1.3.14	-	M	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
APPACOFM_03345	1.6e-124	yadS	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_03346	2.27e-109	-	-	-	S	-	-	-	COG NOG30135 non supervised orthologous group
APPACOFM_03347	2.02e-219	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Peptidase family M48
APPACOFM_03348	7.6e-121	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
APPACOFM_03349	3.64e-45	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
APPACOFM_03350	0.0	-	6.4.1.1	-	C	ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	COG5016 Pyruvate oxaloacetate carboxyltransferase
APPACOFM_03351	3.23e-133	mtgA	2.4.1.129	GT51	M	ko:K03814	ko00550,map00550	ko00000,ko00001,ko01000,ko01003,ko01011	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
APPACOFM_03352	9.48e-131	-	-	-	M	-	-	-	COG2885 Outer membrane protein and related peptidoglycan-associated
APPACOFM_03353	0.0	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_03354	0.0	xynB	-	-	I	-	-	-	pectin acetylesterase
APPACOFM_03355	2.49e-181	-	-	-	-	-	-	-	-
APPACOFM_03356	3.41e-256	-	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
APPACOFM_03357	3.41e-107	-	-	-	KT	-	-	-	Bacterial transcription activator, effector binding domain
APPACOFM_03358	2.27e-241	-	-	-	K	ko:K13652	-	ko00000,ko03000	Bacterial transcription activator, effector binding domain
APPACOFM_03360	2.4e-164	-	-	-	S	ko:K15738	-	ko00000,ko02000	ATP-binding cassette protein, ChvD family
APPACOFM_03361	2.41e-207	-	-	-	S	-	-	-	ATP-binding cassette protein, ChvD family
APPACOFM_03362	0.0	-	-	-	P	-	-	-	Psort location OuterMembrane, score
APPACOFM_03364	1.17e-172	-	-	-	S	-	-	-	Endonuclease Exonuclease phosphatase family protein
APPACOFM_03365	0.0	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score
APPACOFM_03366	8.37e-278	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score
APPACOFM_03367	0.0	-	-	-	S	-	-	-	Putative polysaccharide deacetylase
APPACOFM_03368	9.22e-211	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
APPACOFM_03369	2.52e-284	-	-	-	M	-	-	-	Glycosyltransferase, group 1 family protein
APPACOFM_03370	5.44e-229	-	-	-	M	-	-	-	Pfam:DUF1792
APPACOFM_03371	2.12e-189	-	-	-	M	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_03372	9.43e-72	-	-	-	M	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_03373	0.0	-	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
APPACOFM_03374	4.86e-210	-	-	-	M	-	-	-	Glycosyltransferase like family 2
APPACOFM_03375	2.14e-254	-	-	-	M	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_03376	3.04e-64	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
APPACOFM_03377	2.31e-213	-	-	-	S	-	-	-	Domain of unknown function (DUF4373)
APPACOFM_03378	0.0	-	3.6.4.12	-	L	ko:K17680	-	ko00000,ko01000,ko03029	Psort location Cytoplasmic, score 8.96
APPACOFM_03379	1.12e-103	-	-	-	E	-	-	-	Glyoxalase-like domain
APPACOFM_03380	4.23e-54	-	-	-	S	-	-	-	Domain of unknown function (DUF4248)
APPACOFM_03381	3.73e-98	-	-	-	L	-	-	-	COG NOG31453 non supervised orthologous group
APPACOFM_03382	2.47e-13	-	-	-	-	-	-	-	-
APPACOFM_03383	3.91e-113	-	3.5.1.28	-	V	ko:K01447	-	ko00000,ko01000	Psort location Cytoplasmic, score 8.96
APPACOFM_03384	1.15e-281	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score
APPACOFM_03385	1.13e-219	-	-	-	S	ko:K07011	-	ko00000	Glycosyltransferase, group 2 family protein
APPACOFM_03386	0.0	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_03387	0.0	-	-	-	M	-	-	-	COG NOG36677 non supervised orthologous group
APPACOFM_03388	2.55e-166	-	-	-	MU	-	-	-	COG NOG27134 non supervised orthologous group
APPACOFM_03389	8.37e-307	-	-	-	M	-	-	-	COG NOG26016 non supervised orthologous group
APPACOFM_03390	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
APPACOFM_03391	0.0	nqrA	1.6.5.8	-	C	ko:K00346	-	ko00000,ko01000	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
APPACOFM_03392	4.32e-279	nqrB	1.6.5.8	-	C	ko:K00347	-	ko00000,ko01000	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
APPACOFM_03393	1.38e-158	nqrC	1.6.5.8	-	C	ko:K00348	-	ko00000,ko01000	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
APPACOFM_03394	2.3e-142	nqrD	1.6.5.8	-	C	ko:K00349	-	ko00000,ko01000	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
APPACOFM_03395	3.08e-124	nqrE	1.6.5.8	-	C	ko:K00350	-	ko00000,ko01000	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
APPACOFM_03396	1.05e-310	nqrF	1.6.5.8	-	C	ko:K00351	-	ko00000,ko01000	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway
APPACOFM_03397	1.54e-87	dbpA	3.6.4.13	-	L	ko:K05591	-	ko00000,ko01000,ko03009	ATP-independent RNA helicase DbpA
APPACOFM_03398	3.16e-31	dbpA	3.6.4.13	-	L	ko:K05591	-	ko00000,ko01000,ko03009	ATP-independent RNA helicase DbpA
APPACOFM_03399	7.82e-163	dbpA	3.6.4.13	-	L	ko:K05591	-	ko00000,ko01000,ko03009	ATP-independent RNA helicase DbpA
APPACOFM_03400	5.26e-260	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
APPACOFM_03401	2.97e-214	serA	1.1.1.399, 1.1.1.95	-	C	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
APPACOFM_03402	8.2e-308	-	-	-	S	-	-	-	Conserved protein
APPACOFM_03403	3.06e-137	yigZ	-	-	S	-	-	-	YigZ family
APPACOFM_03404	7.21e-261	hpaIIR	3.1.21.4	-	L	ko:K01155	-	ko00000,ko01000,ko02048	COG NOG26934 non supervised orthologous group
APPACOFM_03405	2.28e-137	-	-	-	C	-	-	-	Nitroreductase family
APPACOFM_03406	0.0	gcvP	1.4.4.2	-	E	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
APPACOFM_03407	6.58e-159	-	-	-	P	-	-	-	Psort location Cytoplasmic, score
APPACOFM_03408	5.96e-146	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
APPACOFM_03409	3.61e-208	-	-	-	S	-	-	-	Protein of unknown function (DUF3298)
APPACOFM_03410	8.72e-48	-	-	-	S	-	-	-	COG NOG14112 non supervised orthologous group
APPACOFM_03411	2.67e-97	-	-	-	J	-	-	-	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
APPACOFM_03412	2.71e-206	-	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
APPACOFM_03413	8.16e-36	-	-	-	-	-	-	-	-
APPACOFM_03414	0.0	-	-	-	P	-	-	-	COG COG4771 Outer membrane receptor for ferrienterochelin and colicins
APPACOFM_03415	4.76e-136	-	-	-	P	-	-	-	COG COG4771 Outer membrane receptor for ferrienterochelin and colicins
APPACOFM_03416	7.06e-62	-	-	-	P	ko:K08364	-	ko00000,ko02000	Heavy metal-associated domain protein
APPACOFM_03417	9.67e-30	copA	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_03418	0.0	copA	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_03419	9.85e-199	-	-	-	K	-	-	-	methylphosphotriester-DNA alkyltransferase and transcriptional regulator (AraC XylS family)
APPACOFM_03420	1.83e-164	lipB	2.3.1.181	-	H	ko:K03801	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate
APPACOFM_03421	1.28e-226	-	-	-	M	-	-	-	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
APPACOFM_03422	0.0	-	-	-	I	-	-	-	pectin acetylesterase
APPACOFM_03423	0.0	-	-	-	S	-	-	-	oligopeptide transporter, OPT family
APPACOFM_03424	8.95e-91	-	-	-	S	-	-	-	Protein of unknown function (DUF1573)
APPACOFM_03426	6.16e-131	-	-	-	S	-	-	-	COG NOG28221 non supervised orthologous group
APPACOFM_03427	4.21e-144	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
APPACOFM_03428	0.0	-	-	-	E	-	-	-	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
APPACOFM_03429	1.25e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
APPACOFM_03430	9.54e-97	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
APPACOFM_03431	1.34e-131	speG	2.3.1.57	-	J	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	ko00000,ko00001,ko00002,ko01000	Acetyltransferase, gnat family
APPACOFM_03432	1.04e-141	-	-	-	K	ko:K07735	-	ko00000,ko03000	Belongs to the UPF0301 (AlgH) family
APPACOFM_03433	0.0	alaC	-	-	E	-	-	-	Aminotransferase, class I II
APPACOFM_03435	4.15e-186	-	-	-	K	ko:K02477	-	ko00000,ko02022	LytTr DNA-binding domain protein
APPACOFM_03436	2.06e-236	-	-	-	T	-	-	-	Histidine kinase
APPACOFM_03437	9.54e-159	-	-	-	M	-	-	-	Outer membrane protein beta-barrel domain
APPACOFM_03438	2.43e-33	-	-	-	S	-	-	-	Domain of unknown function (DUF4136)
APPACOFM_03439	1.67e-79	-	-	-	S	-	-	-	Domain of unknown function (DUF4136)
APPACOFM_03440	9.25e-92	-	-	-	S	-	-	-	Domain of unknown function (DUF4251)
APPACOFM_03441	2.86e-10	-	-	-	S	-	-	-	Domain of unknown function (DUF4251)
APPACOFM_03442	4.38e-93	-	-	-	S	-	-	-	COG NOG32529 non supervised orthologous group
APPACOFM_03443	0.0	-	-	-	S	-	-	-	Phosphoadenosine phosphosulfate reductase family
APPACOFM_03444	1.9e-127	ibrB	-	-	K	-	-	-	Psort location Cytoplasmic, score
APPACOFM_03446	0.0	-	-	-	-	-	-	-	-
APPACOFM_03447	3.01e-142	-	-	-	M	-	-	-	Protein of unknown function (DUF3575)
APPACOFM_03448	0.0	-	-	-	M	-	-	-	COG NOG23378 non supervised orthologous group
APPACOFM_03449	0.0	-	-	-	S	-	-	-	COG NOG34047 non supervised orthologous group
APPACOFM_03450	1.76e-232	-	-	-	S	-	-	-	COG NOG32009 non supervised orthologous group
APPACOFM_03451	1.28e-226	-	-	-	-	-	-	-	-
APPACOFM_03452	7.15e-228	-	-	-	-	-	-	-	-
APPACOFM_03453	1.83e-230	-	4.1.1.35	-	GM	ko:K08678	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko00002,ko01000	NAD dependent epimerase dehydratase family
APPACOFM_03454	2.93e-259	pleD	2.7.13.3	-	T	ko:K11527	-	ko00000,ko01000,ko01001,ko02022	Response regulator receiver domain protein
APPACOFM_03455	0.0	-	-	-	L	-	-	-	DNA-dependent ATPase I and helicase II
APPACOFM_03456	3.09e-177	-	-	-	M	ko:K03832	-	ko00000,ko02000	Gram-negative bacterial TonB protein C-terminal
APPACOFM_03457	3.44e-146	pflA_1	1.97.1.4	-	O	ko:K04069	-	ko00000,ko01000	4Fe-4S single cluster domain
APPACOFM_03458	0.0	addA	-	-	L	-	-	-	Belongs to the helicase family. UvrD subfamily
APPACOFM_03459	1.35e-140	-	-	-	K	ko:K03088	-	ko00000,ko03021	RNA polymerase sigma-70 factor, Bacteroides expansion family 1
APPACOFM_03460	7.49e-236	-	-	-	PT	-	-	-	Domain of unknown function (DUF4974)
APPACOFM_03461	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycosyl hydrolase family 20, catalytic domain protein
APPACOFM_03462	4.93e-173	-	-	-	S	-	-	-	Domain of unknown function
APPACOFM_03463	1.86e-286	-	-	-	N	-	-	-	Concanavalin A-like lectin/glucanases superfamily
APPACOFM_03464	9.5e-289	-	-	-	G	-	-	-	Glycosyl hydrolases family 18
APPACOFM_03465	0.0	-	-	-	S	-	-	-	non supervised orthologous group
APPACOFM_03466	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_03467	1.59e-290	-	-	-	S	-	-	-	Concanavalin A-like lectin/glucanases superfamily
APPACOFM_03468	2.91e-282	-	-	-	G	-	-	-	Putative glycoside hydrolase Family 18, chitinase_18
APPACOFM_03469	0.0	-	-	-	S	-	-	-	Susd and RagB outer membrane lipoprotein
APPACOFM_03470	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_03471	1.7e-299	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
APPACOFM_03473	0.0	-	-	-	P	-	-	-	TonB dependent receptor
APPACOFM_03474	0.0	-	-	-	S	-	-	-	non supervised orthologous group
APPACOFM_03475	2.06e-263	-	-	-	G	-	-	-	Glycosyl hydrolases family 18
APPACOFM_03476	1.14e-288	-	-	-	S	-	-	-	Concanavalin A-like lectin/glucanases superfamily
APPACOFM_03477	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF1735)
APPACOFM_03478	0.0	-	-	-	G	-	-	-	Domain of unknown function (DUF4838)
APPACOFM_03479	1.09e-308	ampG	-	-	EGP	ko:K08218	ko01501,map01501	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_03480	2.03e-254	-	2.4.1.319, 2.4.1.320	-	G	ko:K18785	-	ko00000,ko01000	glycosylase
APPACOFM_03481	0.0	-	-	-	G	-	-	-	Alpha-1,2-mannosidase
APPACOFM_03482	8.71e-75	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
APPACOFM_03483	4.16e-128	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
APPACOFM_03484	0.0	-	-	-	S	-	-	-	Domain of unknown function
APPACOFM_03485	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_03486	0.0	-	-	-	F	ko:K21572	-	ko00000,ko02000	SusD family
APPACOFM_03487	1.55e-24	-	-	-	S	-	-	-	Domain of unknown function
APPACOFM_03488	0.0	-	-	-	S	-	-	-	Domain of unknown function
APPACOFM_03489	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_03490	5.83e-240	-	-	-	F	ko:K21572	-	ko00000,ko02000	SusD family
APPACOFM_03491	0.0	-	-	-	F	ko:K21572	-	ko00000,ko02000	SusD family
APPACOFM_03492	0.0	-	-	-	G	-	-	-	pectate lyase K01728
APPACOFM_03493	2.4e-153	-	-	-	S	-	-	-	Protein of unknown function (DUF3826)
APPACOFM_03494	5.38e-218	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 43 family
APPACOFM_03495	0.0	hypBA2	-	-	G	-	-	-	BNR repeat-like domain
APPACOFM_03496	0.0	-	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Alpha-L-rhamnosidase N-terminal domain protein
APPACOFM_03497	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 28 family
APPACOFM_03498	0.0	-	-	-	Q	-	-	-	cephalosporin-C deacetylase activity
APPACOFM_03499	7.76e-187	-	-	-	M	ko:K07001	-	ko00000	Patatin-like phospholipase
APPACOFM_03500	4.42e-70	-	-	-	IQ	-	-	-	Oxidoreductase, short chain dehydrogenase reductase family protein
APPACOFM_03501	6.21e-95	-	-	-	IQ	-	-	-	Oxidoreductase, short chain dehydrogenase reductase family protein
APPACOFM_03502	0.0	-	-	-	S	-	-	-	Psort location Extracellular, score
APPACOFM_03503	0.0	-	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Alpha-L-rhamnosidase N-terminal domain protein
APPACOFM_03504	0.0	-	-	-	G	-	-	-	Putative collagen-binding domain of a collagenase
APPACOFM_03505	1.4e-305	-	3.2.1.172	GH105	E	ko:K15532	-	ko00000,ko01000	unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
APPACOFM_03506	0.0	-	3.2.1.51	GH95	G	ko:K15923	ko00511,map00511	ko00000,ko00001,ko01000	COG NOG04001 non supervised orthologous group
APPACOFM_03507	1.05e-229	-	1.3.5.2	-	F	ko:K00254	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
APPACOFM_03508	2.62e-195	-	-	-	I	-	-	-	alpha/beta hydrolase fold
APPACOFM_03509	6.2e-128	-	-	-	S	-	-	-	Putative auto-transporter adhesin, head GIN domain
APPACOFM_03510	4.14e-173	yfkO	-	-	C	-	-	-	Nitroreductase family
APPACOFM_03511	1.41e-201	-	-	-	S	-	-	-	COG4422 Bacteriophage protein gp37
APPACOFM_03512	0.0	-	-	-	S	ko:K09955	-	ko00000	protein conserved in bacteria
APPACOFM_03513	0.0	-	-	-	S	-	-	-	Parallel beta-helix repeats
APPACOFM_03514	0.0	-	-	-	G	-	-	-	Alpha-L-rhamnosidase
APPACOFM_03515	1.8e-192	-	-	-	G	-	-	-	Alpha-L-rhamnosidase
APPACOFM_03516	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_03517	2.4e-135	-	-	-	J	-	-	-	COG COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
APPACOFM_03518	0.0	-	-	-	T	-	-	-	PAS domain S-box protein
APPACOFM_03520	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase, family 20, catalytic domain
APPACOFM_03521	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 2 family
APPACOFM_03522	4.44e-160	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
APPACOFM_03523	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
APPACOFM_03526	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
APPACOFM_03527	9.73e-88	-	-	-	G	-	-	-	beta-galactosidase
APPACOFM_03528	4.42e-267	-	-	-	G	-	-	-	beta-galactosidase
APPACOFM_03529	6.17e-315	-	-	-	G	-	-	-	beta-galactosidase
APPACOFM_03530	4.42e-84	-	-	-	S	ko:K09964	-	ko00000	ACT domain
APPACOFM_03531	3.84e-162	-	-	-	K	ko:K07665	ko02020,map02020	ko00000,ko00001,ko00002,ko01504,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
APPACOFM_03532	4.6e-307	arlS_1	-	-	T	-	-	-	histidine kinase DNA gyrase B
APPACOFM_03533	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	Psort location CytoplasmicMembrane, score
APPACOFM_03534	0.0	-	-	-	CO	-	-	-	Thioredoxin-like
APPACOFM_03535	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 2, sugar binding domain protein
APPACOFM_03536	0.0	-	3.1.1.53	-	G	ko:K05970	-	ko00000,ko01000	COG NOG04984 non supervised orthologous group
APPACOFM_03537	0.0	-	-	-	G	-	-	-	hydrolase, family 65, central catalytic
APPACOFM_03538	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
APPACOFM_03540	0.0	-	-	-	T	-	-	-	cheY-homologous receiver domain
APPACOFM_03541	0.0	-	-	-	G	-	-	-	pectate lyase K01728
APPACOFM_03542	0.0	-	-	-	M	-	-	-	Belongs to the glycosyl hydrolase 28 family
APPACOFM_03543	1.47e-276	-	-	-	M	-	-	-	Belongs to the glycosyl hydrolase 28 family
APPACOFM_03544	6.05e-121	-	-	-	K	-	-	-	Sigma-70, region 4
APPACOFM_03545	1.75e-52	-	-	-	-	-	-	-	-
APPACOFM_03546	1.54e-288	-	-	-	G	-	-	-	Major Facilitator Superfamily
APPACOFM_03547	6.26e-170	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.46
APPACOFM_03548	4.96e-113	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
APPACOFM_03549	1.69e-172	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_03550	1.97e-189	vdlC	-	-	S	-	-	-	COG COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
APPACOFM_03551	5.27e-192	-	-	-	S	-	-	-	Domain of unknown function (4846)
APPACOFM_03552	4.9e-145	-	3.1.3.10, 3.1.3.104	-	S	ko:K07025,ko:K20866,ko:K21063	ko00010,ko00740,ko01100,ko01110,ko01120,map00010,map00740,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	HAD hydrolase, family IA, variant 3
APPACOFM_03553	1.17e-246	-	-	-	S	-	-	-	Tetratricopeptide repeat
APPACOFM_03554	0.0	-	-	-	EG	-	-	-	Protein of unknown function (DUF2723)
APPACOFM_03555	1.23e-179	-	-	-	EG	-	-	-	Protein of unknown function (DUF2723)
APPACOFM_03556	4.3e-44	fjo13	-	-	S	-	-	-	COG NOG19122 non supervised orthologous group
APPACOFM_03557	2.33e-120	-	-	-	K	ko:K03088	-	ko00000,ko03021	RNA polymerase sigma-70 factor, ECF subfamily K00960
APPACOFM_03558	7.35e-224	-	-	-	PT	-	-	-	Sigma factor regulatory protein, FecR PupR family
APPACOFM_03559	0.0	-	-	-	P	-	-	-	Carboxypeptidase regulatory-like domain
APPACOFM_03560	0.0	yccM	-	-	C	-	-	-	Psort location CytoplasmicMembrane, score
APPACOFM_03561	3.17e-196	-	-	-	S	ko:K07079	-	ko00000	of the aldo keto reductase family
APPACOFM_03562	5.28e-140	-	-	-	S	ko:K07079	-	ko00000	of the aldo keto reductase family
APPACOFM_03563	1.67e-99	-	-	-	S	-	-	-	COG COG4771 Outer membrane receptor for ferrienterochelin and colicins
APPACOFM_03564	0.0	-	-	-	H	ko:K02014	-	ko00000,ko02000	COG COG4771 Outer membrane receptor for ferrienterochelin and colicins
APPACOFM_03565	1.07e-114	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.46
APPACOFM_03566	0.0	-	-	-	T	-	-	-	Psort location CytoplasmicMembrane, score
APPACOFM_03567	2.31e-278	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_03568	9.37e-276	-	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
APPACOFM_03569	1.87e-224	-	-	-	M	ko:K01993	-	ko00000	Auxiliary transport protein, membrane fusion protein
APPACOFM_03570	0.0	-	-	-	MU	-	-	-	Psort location OuterMembrane, score
APPACOFM_03572	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)
APPACOFM_03573	3.99e-158	-	-	-	K	-	-	-	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
APPACOFM_03574	3.33e-271	qseC	-	-	T	-	-	-	Psort location CytoplasmicMembrane, score
APPACOFM_03575	7.33e-216	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
APPACOFM_03576	4.47e-175	yxlF_1	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	Psort location Cytoplasmic, score 9.12
APPACOFM_03577	2.17e-220	-	-	-	S	-	-	-	NPCBM-associated, NEW3 domain of alpha-galactosidase
APPACOFM_03579	7.07e-97	-	-	-	S	-	-	-	COG NOG14442 non supervised orthologous group
APPACOFM_03580	1.67e-218	-	-	-	S	-	-	-	COG NOG14441 non supervised orthologous group
APPACOFM_03581	0.0	-	-	-	S	-	-	-	Psort location OuterMembrane, score 9.49
APPACOFM_03582	6.5e-246	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
APPACOFM_03583	6.87e-277	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
APPACOFM_03584	2.83e-57	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
APPACOFM_03585	1e-35	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
APPACOFM_03586	1.54e-28	-	-	-	S	-	-	-	Domain of unknown function (DUF4295)
APPACOFM_03587	5.58e-221	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
APPACOFM_03588	0.0	rimO	2.8.4.4	-	J	ko:K14441	-	ko00000,ko01000,ko03009	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12
APPACOFM_03589	2.56e-55	himA	-	-	L	ko:K03530,ko:K04764	-	ko00000,ko03032,ko03036,ko03400	COG0776 Bacterial nucleoid DNA-binding protein
APPACOFM_03590	1.42e-278	-	-	-	L	-	-	-	Belongs to the bacterial histone-like protein family
APPACOFM_03591	4.12e-229	moxR	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
APPACOFM_03592	1.18e-179	-	-	-	S	-	-	-	protein (some members contain a von Willebrand factor type A (vWA) domain)
APPACOFM_03593	5.14e-249	-	-	-	O	-	-	-	Psort location CytoplasmicMembrane, score
APPACOFM_03594	2.48e-228	batA	-	-	S	ko:K07114	-	ko00000,ko02000	Von Willebrand factor type A domain
APPACOFM_03595	2.32e-236	batB	-	-	S	ko:K07114	-	ko00000,ko02000	Von Willebrand factor type A domain
APPACOFM_03596	1.06e-127	batC	-	-	S	-	-	-	Tetratricopeptide repeat protein
APPACOFM_03597	0.0	batD	-	-	S	-	-	-	COG NOG06393 non supervised orthologous group
APPACOFM_03598	4.44e-122	batE	-	-	T	-	-	-	COG NOG22299 non supervised orthologous group
APPACOFM_03599	9.92e-32	batE	-	-	T	-	-	-	COG NOG22299 non supervised orthologous group
APPACOFM_03600	6.54e-63	-	-	-	S	-	-	-	COG NOG19094 non supervised orthologous group
APPACOFM_03601	6.25e-268	uspA	-	-	T	-	-	-	COG0589 Universal stress protein UspA and related nucleotide-binding
APPACOFM_03602	1.22e-284	-	-	-	S	-	-	-	Tetratricopeptide repeat protein
APPACOFM_03603	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
APPACOFM_03604	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Belongs to the ClpA ClpB family
APPACOFM_03605	3.14e-11	htpG	-	-	O	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	ATPase histidine kinase DNA gyrase B HSP90 domain protein
APPACOFM_03606	0.0	htpG	-	-	T	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	ATPase histidine kinase DNA gyrase B HSP90 domain protein
APPACOFM_03607	0.0	-	-	-	M	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
APPACOFM_03611	1.93e-210	dapA	4.3.3.7	-	EM	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
APPACOFM_03612	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
APPACOFM_03613	1.24e-161	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
APPACOFM_03615	5.54e-213	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
APPACOFM_03616	3.84e-186	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
APPACOFM_03617	5.14e-100	-	-	-	K	-	-	-	COG NOG19093 non supervised orthologous group
APPACOFM_03618	1.64e-239	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	COG1466 DNA polymerase III, delta subunit
APPACOFM_03619	7.21e-191	amn	3.2.2.4	-	F	ko:K01241	ko00230,map00230	ko00000,ko00001,ko01000	COG COG0775 Nucleoside phosphorylase
APPACOFM_03620	1.65e-106	-	-	-	V	-	-	-	COG NOG14438 non supervised orthologous group
APPACOFM_03621	0.0	bpeF	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
APPACOFM_03622	1.19e-253	-	-	-	M	-	-	-	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
APPACOFM_03623	0.0	-	-	-	M	-	-	-	Efflux transporter, outer membrane factor lipoprotein, NodT family
APPACOFM_03624	1.08e-153	-	-	-	S	ko:K07164	-	ko00000	Zinc ribbon domain protein
APPACOFM_03625	5.5e-262	yqfO	-	-	C	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
APPACOFM_03626	3.57e-89	-	-	-	S	-	-	-	Domain of unknown function (DUF4891)
APPACOFM_03627	4.37e-57	-	-	-	-	-	-	-	-
APPACOFM_03628	5.54e-173	-	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_03629	6.41e-141	-	3.6.3.21	-	V	ko:K02028,ko:K02068	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
APPACOFM_03630	5.02e-123	-	-	-	S	-	-	-	protein containing a ferredoxin domain
APPACOFM_03631	6.59e-278	aguA	3.5.3.12	-	E	ko:K10536	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.96
APPACOFM_03632	2.67e-220	-	3.5.1.53	-	S	ko:K12251	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	hydrolase, carbon-nitrogen family
APPACOFM_03633	1.44e-86	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.46
APPACOFM_03634	0.0	-	-	-	M	-	-	-	Sulfatase
APPACOFM_03635	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
APPACOFM_03636	2.86e-240	-	-	-	I	-	-	-	lipid kinase, YegS Rv2252 BmrU family
APPACOFM_03637	7e-287	bioF	2.3.1.29, 2.3.1.47	-	E	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Beta-eliminating lyase
APPACOFM_03638	2.33e-74	-	-	-	S	-	-	-	Lipocalin-like
APPACOFM_03639	3.02e-75	-	-	-	-	-	-	-	-
APPACOFM_03640	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
APPACOFM_03641	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_03642	2.78e-277	-	-	-	V	-	-	-	MacB-like periplasmic core domain
APPACOFM_03643	0.0	-	-	-	V	-	-	-	COG NOG11095 non supervised orthologous group
APPACOFM_03644	0.0	-	-	-	V	-	-	-	MacB-like periplasmic core domain
APPACOFM_03645	4.83e-154	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	bacteriocin export ABC transporter, lactococcin 972 group
APPACOFM_03646	0.0	-	-	-	V	-	-	-	Efflux ABC transporter, permease protein
APPACOFM_03647	1.77e-282	-	-	-	M	ko:K02005	-	ko00000	Efflux transporter, RND family, MFP subunit
APPACOFM_03648	0.0	-	-	-	MU	-	-	-	Psort location OuterMembrane, score
APPACOFM_03649	6.21e-243	-	-	-	T	-	-	-	Sigma-54 interaction domain protein
APPACOFM_03650	5.58e-62	-	-	-	T	-	-	-	Sigma-54 interaction domain protein
APPACOFM_03651	1.27e-291	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
APPACOFM_03652	8.1e-36	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_03653	5.27e-185	-	-	-	Q	-	-	-	Protein of unknown function (DUF1698)
APPACOFM_03656	7.98e-166	smtA	2.1.1.223	-	J	ko:K15460	-	ko00000,ko01000,ko03016	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
APPACOFM_03657	0.0	lon	3.4.21.53	-	O	ko:K01338	ko04112,map04112	ko00000,ko00001,ko01000,ko01002	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
APPACOFM_03658	1.51e-281	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
APPACOFM_03659	8.88e-248	lptG	-	-	S	ko:K11720	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Permease, YjgP YjgQ family
APPACOFM_03660	5.56e-93	-	-	-	O	-	-	-	COG NOG28456 non supervised orthologous group
APPACOFM_03661	4.76e-288	serB	3.1.3.3	-	ET	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01009	Psort location Cytoplasmic, score 8.96
APPACOFM_03662	1.47e-284	deaD	-	-	L	-	-	-	Belongs to the DEAD box helicase family
APPACOFM_03663	1.62e-186	-	-	-	S	-	-	-	COG NOG26711 non supervised orthologous group
APPACOFM_03664	2.23e-314	ugd	1.1.1.22	-	C	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
APPACOFM_03665	4.64e-129	rfbC	5.1.3.13	-	G	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
APPACOFM_03666	5.02e-238	-	-	-	D	-	-	-	sporulation
APPACOFM_03668	6.76e-68	-	-	-	T	-	-	-	FHA domain protein
APPACOFM_03669	0.0	uxaB	1.1.1.17, 1.1.1.58	-	C	ko:K00009,ko:K00041	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the mannitol dehydrogenase family. UxaB subfamily
APPACOFM_03670	2.68e-253	-	-	-	K	ko:K02529	-	ko00000,ko03000	Psort location Cytoplasmic, score
APPACOFM_03671	0.0	uxaC	5.3.1.12	-	G	ko:K01812	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	glucuronate isomerase
APPACOFM_03674	2.72e-195	vicX	-	-	S	-	-	-	Metallo-beta-lactamase domain protein
APPACOFM_03675	0.0	dtpD	-	-	E	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_03676	2.97e-93	-	-	-	G	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_03677	1.19e-54	-	-	-	-	-	-	-	-
APPACOFM_03678	0.0	-	-	-	T	-	-	-	COG0642 Signal transduction histidine kinase
APPACOFM_03679	1.61e-93	nlpE	-	-	MP	-	-	-	lipoprotein NlpE involved in copper resistance
APPACOFM_03680	1.87e-92	-	-	-	S	ko:K15977	-	ko00000	Psort location CytoplasmicMembrane, score 9.46
APPACOFM_03681	1.61e-125	-	-	-	S	-	-	-	COG NOG23374 non supervised orthologous group
APPACOFM_03682	0.0	-	-	-	M	-	-	-	Outer membrane protein, OMP85 family
APPACOFM_03683	2.71e-299	-	-	-	U	-	-	-	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
APPACOFM_03684	3.12e-79	-	-	-	K	-	-	-	Penicillinase repressor
APPACOFM_03685	7.15e-179	aviRb	-	-	J	ko:K03437	-	ko00000,ko03016	RNA methyltransferase, TrmH
APPACOFM_03686	1.58e-79	-	-	-	-	-	-	-	-
APPACOFM_03687	5.27e-226	-	-	-	S	-	-	-	COG NOG25370 non supervised orthologous group
APPACOFM_03688	1.84e-155	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
APPACOFM_03689	2.94e-80	yocK	-	-	T	-	-	-	RNA polymerase-binding protein DksA
APPACOFM_03690	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
APPACOFM_03691	4.53e-240	yhiM	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_03693	0.0	ramA_2	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_03694	2.05e-235	-	-	-	P	ko:K03325	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_03695	5.1e-316	-	3.6.3.16	-	D	ko:K01551	-	ko00000,ko01000,ko02000	Anion-transporting ATPase
APPACOFM_03696	1.6e-58	-	3.6.3.16	-	D	ko:K01551	-	ko00000,ko01000,ko02000	Anion-transporting ATPase
APPACOFM_03697	8.06e-74	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_03698	3.21e-153	-	-	-	CO	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_03699	2.55e-100	-	-	-	-	-	-	-	-
APPACOFM_03700	1.64e-43	-	-	-	CO	-	-	-	Thioredoxin domain
APPACOFM_03701	8.74e-69	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_03702	0.0	-	-	-	S	-	-	-	Domain of unknonw function from B. Theta Gene description (DUF3874)
APPACOFM_03703	3.44e-73	-	-	-	L	-	-	-	Bacterial DNA-binding protein
APPACOFM_03704	0.0	-	-	-	P	ko:K08138	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
APPACOFM_03705	0.0	xylA	5.3.1.5	-	G	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
APPACOFM_03706	0.0	xylB_2	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Carbohydrate kinase, FGGY family protein
APPACOFM_03707	1.03e-171	-	-	-	F	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_03708	2.82e-198	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	COG0351 Hydroxymethylpyrimidine phosphomethylpyrimidine kinase
APPACOFM_03709	1.93e-209	fabD	2.3.1.39	-	I	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	malonyl CoA-acyl carrier protein transacylase
APPACOFM_03710	3.08e-265	sucC	6.2.1.5	-	F	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
APPACOFM_03711	3.17e-199	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
APPACOFM_03712	6.13e-174	-	-	-	S	-	-	-	Domain of unknown function (DUF4396)
APPACOFM_03713	3.72e-29	-	-	-	-	-	-	-	-
APPACOFM_03714	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	Glutamate--ammonia ligase, catalytic domain protein
APPACOFM_03715	7.23e-51	-	-	-	S	-	-	-	COG COG0724 RNA-binding proteins (RRM domain)
APPACOFM_03716	7.35e-22	-	-	-	-	-	-	-	-
APPACOFM_03717	1.1e-176	-	-	-	J	-	-	-	Psort location Cytoplasmic, score
APPACOFM_03718	7.01e-124	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
APPACOFM_03719	3.44e-61	-	-	-	-	-	-	-	-
APPACOFM_03720	3.48e-193	-	2.7.4.1	-	S	ko:K22468	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Polyphosphate kinase 2 (PPK2)
APPACOFM_03721	4.68e-110	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.46
APPACOFM_03722	8.96e-140	-	-	-	S	-	-	-	Tat pathway signal sequence domain protein
APPACOFM_03723	8.8e-49	-	-	-	S	-	-	-	Tat pathway signal sequence domain protein
APPACOFM_03724	1.12e-50	yccM_2	-	-	C	-	-	-	Psort location CytoplasmicMembrane, score
APPACOFM_03725	6.28e-312	yccM_2	-	-	C	-	-	-	Psort location CytoplasmicMembrane, score
APPACOFM_03726	2.16e-197	-	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
APPACOFM_03727	0.0	amyA2	-	-	G	-	-	-	Alpha amylase, catalytic domain
APPACOFM_03728	1.82e-112	-	-	-	S	-	-	-	COG NOG29454 non supervised orthologous group
APPACOFM_03729	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	1,4-alpha-glucan branching enzyme
APPACOFM_03730	2.75e-100	tabA_2	-	-	G	-	-	-	YhcH YjgK YiaL family protein
APPACOFM_03731	1.02e-166	-	-	-	S	-	-	-	TIGR02453 family
APPACOFM_03732	8.88e-144	-	4.1.3.38	-	EH	ko:K02619	ko00790,map00790	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.96
APPACOFM_03733	1.64e-239	pabB	2.6.1.85	-	EH	ko:K01665	ko00790,map00790	ko00000,ko00001,ko01000	COG COG0147 Anthranilate para-aminobenzoate synthases component I
APPACOFM_03734	1.49e-185	-	-	-	S	ko:K02651	ko04112,map04112	ko00000,ko00001,ko02035,ko02044	COG NOG28004 non supervised orthologous group
APPACOFM_03735	1.07e-266	-	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	Trypsin
APPACOFM_03736	2.18e-304	-	-	-	-	-	-	-	-
APPACOFM_03737	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat protein
APPACOFM_03740	0.0	-	-	-	S	-	-	-	COG NOG22466 non supervised orthologous group
APPACOFM_03742	0.0	-	-	-	T	-	-	-	helix_turn_helix, arabinose operon control protein
APPACOFM_03743	2.34e-35	-	-	-	-	-	-	-	-
APPACOFM_03744	5.82e-136	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
APPACOFM_03746	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
APPACOFM_03747	0.0	-	-	-	P	-	-	-	Protein of unknown function (DUF229)
APPACOFM_03748	0.0	-	-	-	E	ko:K21572	-	ko00000,ko02000	Pfam:SusD
APPACOFM_03749	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_03750	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_03751	6.15e-236	-	-	-	PT	-	-	-	Domain of unknown function (DUF4974)
APPACOFM_03752	8.19e-134	-	-	-	K	ko:K03088	-	ko00000,ko03021	RNA polymerase sigma-70 factor
APPACOFM_03753	0.0	ydaH	-	-	H	ko:K12942	-	ko00000	Psort location CytoplasmicMembrane, score
APPACOFM_03754	4.03e-105	-	-	-	T	-	-	-	Response regulator receiver domain
APPACOFM_03755	7.22e-50	-	-	-	T	-	-	-	Response regulator receiver domain
APPACOFM_03756	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
APPACOFM_03757	8.9e-219	prs	2.7.6.1	-	EF	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	COG0462 Phosphoribosylpyrophosphate synthetase
APPACOFM_03758	4.21e-38	-	2.7.11.1	-	S	ko:K12132	-	ko00000,ko01000,ko01001	phosphatidylinositol-4-phosphate 5-kinase family protein K00889
APPACOFM_03759	1.32e-310	-	-	-	S	-	-	-	Peptidase M16 inactive domain
APPACOFM_03760	4.51e-160	kdsB	2.7.7.38	-	H	ko:K00979	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
APPACOFM_03761	2.44e-80	folK2	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	COG NOG22185 non supervised orthologous group
APPACOFM_03762	0.0	mrcA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	COG5009 Membrane carboxypeptidase penicillin-binding protein
APPACOFM_03763	6.88e-186	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
APPACOFM_03764	4.02e-109	pyrI	-	-	F	ko:K00610	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002	Involved in allosteric regulation of aspartate carbamoyltransferase
APPACOFM_03765	3.37e-141	-	-	-	S	-	-	-	COG COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
APPACOFM_03766	1.19e-178	-	-	-	S	-	-	-	COG NOG27381 non supervised orthologous group
APPACOFM_03767	2.12e-311	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
APPACOFM_03768	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Formyltetrahydrofolate synthetase
APPACOFM_03769	0.0	aspT	-	-	S	ko:K07085	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_03770	0.0	aspD	4.1.1.12	-	E	ko:K09758	ko00250,ko00270,ko01100,ko01230,map00250,map00270,map01100,map01230	ko00000,ko00001,ko01000	COG COG0436 Aspartate tyrosine aromatic aminotransferase
APPACOFM_03771	0.0	-	-	-	P	-	-	-	Psort location OuterMembrane, score
APPACOFM_03772	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
APPACOFM_03773	3.4e-162	-	-	-	K	-	-	-	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
APPACOFM_03775	4.83e-120	-	-	-	S	-	-	-	COG NOG28927 non supervised orthologous group
APPACOFM_03776	3.24e-250	-	-	-	GM	-	-	-	NAD(P)H-binding
APPACOFM_03777	8.6e-220	-	-	-	K	-	-	-	transcriptional regulator (AraC family)
APPACOFM_03778	1.6e-210	-	-	-	K	-	-	-	transcriptional regulator (AraC family)
APPACOFM_03779	1.29e-292	-	-	-	S	-	-	-	Clostripain family
APPACOFM_03780	9.35e-225	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
APPACOFM_03782	1.72e-54	-	-	-	S	-	-	-	COG NOG18433 non supervised orthologous group
APPACOFM_03783	6.15e-139	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_03784	0.0	uvrD2	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_03785	0.0	-	-	-	S	-	-	-	COG NOG28036 non supervised orthologous group
APPACOFM_03786	1.69e-200	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
APPACOFM_03787	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
APPACOFM_03788	1.05e-127	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
APPACOFM_03789	4.1e-93	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
APPACOFM_03790	1.13e-40	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
APPACOFM_03791	1.16e-265	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
APPACOFM_03792	5.76e-82	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
APPACOFM_03793	5.3e-51	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	ATP synthase, delta epsilon subunit, beta-sandwich domain protein
APPACOFM_03794	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
APPACOFM_03795	1.26e-88	-	-	-	-	-	-	-	-
APPACOFM_03796	2.71e-237	-	-	-	L	-	-	-	Primase C terminal 1 (PriCT-1)
APPACOFM_03797	0.0	-	-	-	L	-	-	-	Primase C terminal 1 (PriCT-1)
APPACOFM_03798	6.4e-54	-	-	-	S	-	-	-	Domain of unknown function (DUF4248)
APPACOFM_03799	2.38e-93	-	-	-	L	-	-	-	Bacterial DNA-binding protein
APPACOFM_03800	4.54e-104	-	-	-	V	-	-	-	N-acetylmuramoyl-L-alanine amidase
APPACOFM_03801	4.58e-07	-	-	-	-	-	-	-	-
APPACOFM_03802	5.27e-184	-	-	-	M	-	-	-	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
APPACOFM_03803	4.69e-282	purT	2.1.2.2	-	F	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
APPACOFM_03804	6.48e-310	-	-	-	NU	-	-	-	Lipid A 3-O-deacylase (PagL)
APPACOFM_03805	8.83e-153	cat	2.3.1.28	-	V	ko:K19271	-	br01600,ko00000,ko01000,ko01504	Chloramphenicol acetyltransferase
APPACOFM_03806	0.0	-	-	-	H	-	-	-	COG NOG06391 non supervised orthologous group
APPACOFM_03807	0.0	relA	2.7.6.5, 3.1.7.2	-	KT	ko:K00951,ko:K01139	ko00230,map00230	ko00000,ko00001,ko01000,ko03009	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
APPACOFM_03808	2.37e-52	relA	2.7.6.5, 3.1.7.2	-	KT	ko:K00951,ko:K01139	ko00230,map00230	ko00000,ko00001,ko01000,ko03009	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
APPACOFM_03809	1.34e-259	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
APPACOFM_03810	2.4e-192	panB	2.1.2.11	-	H	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
APPACOFM_03811	1.99e-153	pgmB	-	-	S	-	-	-	HAD hydrolase, family IA, variant 3
APPACOFM_03812	5.79e-185	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_03813	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_03814	3.84e-154	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	bacteriocin export ABC transporter, lactococcin 972 group
APPACOFM_03815	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_03816	4.37e-201	-	-	-	S	-	-	-	Ser Thr phosphatase family protein
APPACOFM_03817	5.58e-179	-	-	-	S	-	-	-	COG NOG27188 non supervised orthologous group
APPACOFM_03818	2.05e-315	zraR_2	-	-	T	-	-	-	COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains
APPACOFM_03819	1.69e-314	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
APPACOFM_03820	1.62e-151	-	-	-	K	-	-	-	Crp-like helix-turn-helix domain
APPACOFM_03821	0.0	hcp	1.7.99.1	-	C	ko:K05601	ko00910,map00910	ko00000,ko00001,ko01000	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O
APPACOFM_03822	1.05e-272	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease family
APPACOFM_03823	0.0	cvrA	-	-	P	ko:K11105	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_03824	0.0	-	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	COG COG1022 Long-chain acyl-CoA synthetases (AMP-forming)
APPACOFM_03825	0.0	-	3.2.1.20	GH31	S	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG NOG06228 non supervised orthologous group
APPACOFM_03826	8.58e-162	cusR	-	-	T	ko:K07665	ko02020,map02020	ko00000,ko00001,ko00002,ko01504,ko02022	Transcriptional regulatory protein, C terminal
APPACOFM_03827	4.34e-299	arlS_2	-	-	T	-	-	-	histidine kinase DNA gyrase B
APPACOFM_03828	0.0	czcA_1	-	-	P	ko:K15726	-	ko00000,ko02000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
APPACOFM_03829	7.32e-259	czcB	-	-	M	ko:K15727	-	ko00000,ko02000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
APPACOFM_03830	1.17e-289	czcC	-	-	MU	ko:K15725	-	ko00000,ko02000	Outer membrane efflux protein
APPACOFM_03831	1.61e-85	-	-	-	O	-	-	-	Glutaredoxin
APPACOFM_03832	5.72e-284	-	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
APPACOFM_03833	4.21e-198	-	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
APPACOFM_03834	1.41e-67	-	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
APPACOFM_03841	4.18e-285	nspC	4.1.1.96	-	E	ko:K13747	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.96
APPACOFM_03842	4.63e-130	-	-	-	S	-	-	-	Flavodoxin-like fold
APPACOFM_03843	0.0	-	-	-	V	-	-	-	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
APPACOFM_03844	0.0	-	-	-	MU	-	-	-	Psort location OuterMembrane, score
APPACOFM_03845	0.0	-	-	-	V	-	-	-	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
APPACOFM_03846	1.11e-240	-	-	-	M	-	-	-	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
APPACOFM_03847	7.15e-34	-	-	-	E	-	-	-	Transglutaminase-like
APPACOFM_03848	9.96e-124	-	-	-	E	-	-	-	Transglutaminase-like
APPACOFM_03849	2.37e-186	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_03850	1.14e-99	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_03851	6.24e-141	-	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
APPACOFM_03852	3.18e-196	-	3.2.1.3	GH15	G	ko:K01178	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Domain of unknown function (DUF5127)
APPACOFM_03853	2.83e-13	-	-	-	E	-	-	-	non supervised orthologous group
APPACOFM_03854	7.95e-99	-	-	-	E	-	-	-	non supervised orthologous group
APPACOFM_03855	1.65e-176	-	-	-	E	-	-	-	non supervised orthologous group
APPACOFM_03856	6.82e-44	-	-	-	S	-	-	-	protein BT4048 SWALL AAO79153 (EMBL AE016943) (373 aa) fasta scores E()
APPACOFM_03857	5.36e-06	-	-	-	S	-	-	-	protein BT4048 SWALL AAO79153 (EMBL AE016943) (373 aa) fasta scores E()
APPACOFM_03859	3.94e-08	-	-	-	S	-	-	-	NVEALA protein
APPACOFM_03860	1.35e-203	-	-	-	S	-	-	-	TolB-like 6-blade propeller-like
APPACOFM_03861	1.63e-13	-	-	-	S	-	-	-	NVEALA protein
APPACOFM_03864	2.11e-271	-	-	-	S	-	-	-	ATPase (AAA superfamily)
APPACOFM_03866	6.35e-256	-	-	-	S	-	-	-	TolB-like 6-blade propeller-like
APPACOFM_03867	2.86e-122	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 9.46
APPACOFM_03868	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
APPACOFM_03869	0.0	-	-	-	M	-	-	-	COG3209 Rhs family protein
APPACOFM_03870	8.49e-150	sodB	1.15.1.1	-	C	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
APPACOFM_03871	0.0	-	-	-	T	-	-	-	histidine kinase DNA gyrase B
APPACOFM_03872	7.03e-40	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	thiamine biosynthesis protein ThiS
APPACOFM_03873	1.19e-142	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
APPACOFM_03874	3.52e-177	thiG	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
APPACOFM_03875	0.0	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
APPACOFM_03876	9.33e-279	thiH	4.1.99.19	-	C	ko:K03150	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Thiazole biosynthesis protein ThiH
APPACOFM_03877	1.92e-122	moeZ	2.7.7.80, 2.8.1.11	-	H	ko:K21029,ko:K21147	ko04122,map04122	ko00000,ko00001,ko01000	involved in molybdopterin and thiamine biosynthesis family 2
APPACOFM_03878	6.22e-146	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Thiamine monophosphate synthase TENI
APPACOFM_03879	2.59e-101	-	-	-	M	-	-	-	COG NOG19089 non supervised orthologous group
APPACOFM_03880	1.64e-119	-	-	-	M	-	-	-	Outer membrane protein beta-barrel domain
APPACOFM_03881	0.0	ppdK	2.7.9.1	-	G	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the PEP-utilizing enzyme family
APPACOFM_03882	0.0	rumA	2.1.1.190	-	H	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
APPACOFM_03883	5.82e-221	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
APPACOFM_03884	2.1e-99	-	-	-	-	-	-	-	-
APPACOFM_03885	2.99e-60	-	-	-	C	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_03886	0.0	-	-	-	C	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_03887	1.85e-150	-	-	-	S	-	-	-	Domain of unknown function (DUF4858)
APPACOFM_03888	1.23e-227	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Psort location Cytoplasmic, score
APPACOFM_03889	3.34e-256	rmuC	-	-	S	ko:K09760	-	ko00000	RmuC family
APPACOFM_03890	0.0	-	-	-	KT	-	-	-	Peptidase, M56 family
APPACOFM_03891	9.89e-83	-	-	-	K	-	-	-	Transcriptional regulator, BlaI MecI CopY family
APPACOFM_03892	1.84e-298	nhaA	-	-	P	ko:K03313	-	ko00000,ko02000	) H( ) antiporter that extrudes sodium in exchange for external protons
APPACOFM_03893	9.39e-270	-	-	-	P	-	-	-	Psort location CytoplasmicMembrane, score
APPACOFM_03894	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
APPACOFM_03895	4.95e-40	-	-	-	S	-	-	-	COG NOG33517 non supervised orthologous group
APPACOFM_03897	1.35e-102	-	-	-	S	-	-	-	COG NOG16874 non supervised orthologous group
APPACOFM_03898	5.95e-192	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Psort location Cytoplasmic, score 9.97
APPACOFM_03899	9.2e-286	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	Metal ion transporter, metal ion (Mn2 Fe2 ) transporter (Nramp) family
APPACOFM_03900	1.63e-56	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_03901	1.98e-178	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
APPACOFM_03902	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Psort location Cytoplasmic, score
APPACOFM_03903	0.0	otsB	2.4.1.15, 3.1.3.12	GT20	G	ko:K16055	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000,ko01003	Trehalose-phosphatase
APPACOFM_03904	2.77e-297	-	3.2.1.3	GH15	G	ko:K01178	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolases family 15
APPACOFM_03905	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
APPACOFM_03906	2.71e-194	ispE	2.7.1.148	-	F	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
APPACOFM_03907	7.43e-59	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
APPACOFM_03908	1.71e-177	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
APPACOFM_03909	1.99e-118	rnfA	-	-	C	ko:K03617	-	ko00000	Part of a membrane complex involved in electron transport
APPACOFM_03910	1.92e-127	rnfE	-	-	C	ko:K03613	-	ko00000	Part of a membrane complex involved in electron transport
APPACOFM_03911	4.28e-154	rnfG	-	-	C	ko:K03612	-	ko00000	Part of a membrane complex involved in electron transport
APPACOFM_03912	5.9e-233	rnfD	-	-	C	ko:K03614	-	ko00000	Part of a membrane complex involved in electron transport
APPACOFM_03913	0.0	rnfC	-	-	C	ko:K03615	-	ko00000	Part of a membrane complex involved in electron transport
APPACOFM_03914	4.61e-153	rnfB	-	-	C	ko:K03616	-	ko00000	electron transport complex, RnfABCDGE type, B subunit
APPACOFM_03915	1.33e-90	-	-	-	T	ko:K03803	-	ko00000,ko03021	Positive regulator of sigma(E), RseC MucC
APPACOFM_03916	1.93e-09	-	-	-	-	-	-	-	-
APPACOFM_03917	8.72e-109	-	-	-	L	-	-	-	COG NOG29624 non supervised orthologous group
APPACOFM_03918	0.0	-	-	-	DM	-	-	-	Chain length determinant protein
APPACOFM_03919	1.5e-167	-	-	-	M	ko:K01991	ko02026,map02026	ko00000,ko00001,ko02000	COG1596 Periplasmic protein involved in polysaccharide export
APPACOFM_03920	6.29e-114	-	-	-	M	-	-	-	Glycosyl transferase 4-like
APPACOFM_03921	5.96e-89	-	-	-	EH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
APPACOFM_03922	5.21e-101	-	-	-	G	-	-	-	HpcH/HpaI aldolase/citrate lyase family
APPACOFM_03923	6.91e-87	epsL	-	-	M	ko:K13012	-	ko00000,ko01005	Bacterial sugar transferase
APPACOFM_03924	2.92e-61	-	-	GT2	S	ko:K19425	-	ko00000,ko01000,ko01003	COG0463 Glycosyltransferases involved in cell wall biogenesis
APPACOFM_03926	9.17e-41	-	-	-	S	-	-	-	EpsG family
APPACOFM_03927	1.86e-38	-	-	-	M	-	-	-	Glycosyl transferases group 1
APPACOFM_03928	1.63e-171	gmhB	2.7.7.71	-	M	ko:K15669	ko00540,map00540	ko00000,ko00001,ko01000	Nucleotidyl transferase
APPACOFM_03930	2.13e-260	-	-	-	GM	-	-	-	Polysaccharide biosynthesis protein
APPACOFM_03931	1.39e-141	-	-	-	S	-	-	-	Polysaccharide biosynthesis protein
APPACOFM_03932	1.24e-243	-	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	UDP-N-acetylglucosamine 2-epimerase
APPACOFM_03933	3.86e-165	-	1.1.1.133	-	C	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
APPACOFM_03934	1.98e-236	fnlA	5.1.3.2	-	GM	ko:K17716	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Polysaccharide biosynthesis protein C-terminal
APPACOFM_03935	5.75e-246	-	5.1.3.6	-	M	ko:K08679	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	NAD dependent epimerase dehydratase family
APPACOFM_03936	6.89e-314	ugd	1.1.1.22	-	C	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
APPACOFM_03937	0.0	wbpM	-	-	GM	-	-	-	Polysaccharide biosynthesis protein
APPACOFM_03938	2.59e-78	-	-	-	S	-	-	-	UpxZ family of transcription anti-terminator antagonists
APPACOFM_03939	1.73e-138	-	-	-	K	-	-	-	KOW (Kyprides, Ouzounis, Woese) motif.
APPACOFM_03940	9.43e-233	-	-	-	L	-	-	-	COG NOG21178 non supervised orthologous group
APPACOFM_03941	6.53e-89	-	-	-	S	-	-	-	Domain of unknown function, B. Theta Gene description (DUF4119)
APPACOFM_03942	1.04e-82	-	-	-	S	-	-	-	WYL_2, Sm-like SH3 beta-barrel fold
APPACOFM_03943	2.3e-184	-	-	-	L	-	-	-	COG NOG19076 non supervised orthologous group
APPACOFM_03944	0.0	-	-	-	M	-	-	-	Protein of unknown function (DUF3078)
APPACOFM_03945	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
APPACOFM_03946	0.0	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins
APPACOFM_03947	7.51e-316	-	-	-	V	-	-	-	MATE efflux family protein
APPACOFM_03948	0.0	pop	-	-	EU	-	-	-	Peptidase, S9A B C family, catalytic domain protein
APPACOFM_03949	6.15e-161	-	-	-	-	-	-	-	-
APPACOFM_03950	6.48e-125	-	-	-	S	-	-	-	COG COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
APPACOFM_03951	2.68e-255	-	-	-	S	-	-	-	of the beta-lactamase fold
APPACOFM_03952	8.05e-239	-	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_03953	6.67e-86	-	-	-	K	ko:K10947	-	ko00000,ko03000	transcriptional regulator PadR family
APPACOFM_03954	3.23e-123	paiA	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_03955	0.0	-	-	-	P	ko:K03305	-	ko00000	amino acid peptide transporter
APPACOFM_03956	4.82e-113	ybaK	-	-	H	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
APPACOFM_03957	0.0	uvrA2	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
APPACOFM_03958	0.0	lysM	-	-	M	-	-	-	LysM domain
APPACOFM_03959	1.39e-170	-	-	-	S	-	-	-	Outer membrane protein beta-barrel domain
APPACOFM_03960	2.75e-95	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
APPACOFM_03961	4.8e-72	rpoZ	-	-	S	-	-	-	COG NOG14434 non supervised orthologous group
APPACOFM_03962	1.97e-188	yfiO	-	-	S	ko:K05807	-	ko00000,ko02000	outer membrane assembly lipoprotein YfiO
APPACOFM_03963	1.02e-94	-	-	-	S	-	-	-	ACT domain protein
APPACOFM_03964	0.0	-	6.2.1.30	-	H	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	ko00000,ko00001,ko01000	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
APPACOFM_03965	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
APPACOFM_03967	4.47e-169	-	-	-	E	-	-	-	COG2755 Lysophospholipase L1 and related
APPACOFM_03968	4.31e-156	-	-	-	S	-	-	-	Domain of unknown function (DUF4919)
APPACOFM_03969	9.81e-149	sanA	-	-	S	ko:K03748	-	ko00000	Psort location CytoplasmicMembrane, score 9.82
APPACOFM_03970	1.45e-110	-	-	-	J	-	-	-	Threonine alanine tRNA ligase second additional domain protein
APPACOFM_03971	2.2e-85	hsp20	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
APPACOFM_03972	3.96e-254	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_03973	5.86e-238	ybhS	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_03974	0.0	-	-	-	G	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
APPACOFM_03975	2.5e-205	-	-	-	M	ko:K01993	-	ko00000	COG COG0845 Membrane-fusion protein
APPACOFM_03976	2.8e-288	-	-	-	MU	-	-	-	COG NOG26656 non supervised orthologous group
APPACOFM_03977	1.93e-210	-	-	-	K	-	-	-	transcriptional regulator (AraC family)
APPACOFM_03978	8.1e-171	manC	2.7.7.13	-	M	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	ko00000,ko00001,ko00002,ko01000	mannose-1-phosphate guanylyltransferase
APPACOFM_03979	5.22e-74	manC	2.7.7.13	-	M	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	ko00000,ko00001,ko00002,ko01000	mannose-1-phosphate guanylyltransferase
APPACOFM_03980	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ)
APPACOFM_03981	1.17e-291	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
APPACOFM_03982	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Psort location Cytoplasmic, score 8.96
APPACOFM_03983	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
APPACOFM_03984	0.0	gltB	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Class II glutamine amidotransferase
APPACOFM_03985	0.0	gltD	1.4.1.13, 1.4.1.14	-	E	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	COG0493 NADPH-dependent glutamate synthase beta chain and related
APPACOFM_03986	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase, glutamine-hydrolyzing
APPACOFM_03987	3.68e-173	-	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
APPACOFM_03988	4.04e-67	-	-	-	CO	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Thioredoxin
APPACOFM_03989	5.49e-195	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
APPACOFM_03990	2.98e-312	dapL	2.6.1.83	-	H	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate
APPACOFM_03991	1.34e-173	-	-	-	S	-	-	-	Psort location OuterMembrane, score
APPACOFM_03992	8.69e-76	glnB	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Belongs to the P(II) protein family
APPACOFM_03993	0.0	amt	-	-	P	ko:K03320	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_03994	4.12e-61	glnA	6.3.1.2	-	S	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	Glutamate--ammonia ligase, catalytic domain protein
APPACOFM_03995	0.0	glnA	6.3.1.2	-	S	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	Glutamate--ammonia ligase, catalytic domain protein
APPACOFM_03996	2.44e-129	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_03997	0.0	ppk	2.7.4.1	-	H	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
APPACOFM_03998	3.44e-208	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	Ppx GppA phosphatase family
APPACOFM_03999	1.64e-166	cypM_2	-	-	Q	-	-	-	Nodulation protein S (NodS)
APPACOFM_04000	0.0	-	-	-	P	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_04001	2.04e-276	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
APPACOFM_04002	1.02e-277	yqhD	-	-	C	ko:K08325	ko00640,map00640	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
APPACOFM_04003	2.22e-21	-	-	-	-	-	-	-	-
APPACOFM_04004	4.93e-287	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
APPACOFM_04005	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Anthranilate synthase component I
APPACOFM_04006	9.68e-134	trpG	2.6.1.85, 4.1.3.27	-	EH	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Glutamine amidotransferase, class I
APPACOFM_04007	4.34e-236	trpD	2.4.2.18, 4.1.3.27	-	F	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
APPACOFM_04008	6.17e-175	trpC	4.1.1.48	-	E	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
APPACOFM_04009	8.15e-149	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
APPACOFM_04010	1.83e-183	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
APPACOFM_04011	4.14e-257	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase, type I
APPACOFM_04012	0.0	-	-	-	S	-	-	-	COG NOG06028 non supervised orthologous group
APPACOFM_04014	3.5e-81	-	-	-	T	-	-	-	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
APPACOFM_04015	4.26e-213	-	-	-	M	-	-	-	COG COG2148 Sugar transferases involved in lipopolysaccharide synthesis
APPACOFM_04016	2.18e-208	-	-	-	M	-	-	-	probably involved in cell wall biogenesis
APPACOFM_04017	1.92e-147	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 9.26
APPACOFM_04018	4.5e-135	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_04019	8.38e-169	-	-	-	D	ko:K07322	-	ko00000	Hemerythrin HHE cation binding domain protein
APPACOFM_04020	1.39e-202	purH2	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	COG0138 AICAR transformylase IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful)
APPACOFM_04021	5.07e-75	purH2	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	COG0138 AICAR transformylase IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful)
APPACOFM_04022	1.36e-121	fldA	-	-	C	ko:K03839	-	ko00000	Low-potential electron donor to a number of redox enzymes
APPACOFM_04023	4.1e-84	-	-	-	S	-	-	-	Protein of unknown function (DUF2023)
APPACOFM_04024	4.59e-247	-	1.8.5.2	-	S	ko:K16936,ko:K16937	ko00920,ko01120,map00920,map01120	ko00000,ko00001,ko01000	TQO small subunit DoxD
APPACOFM_04025	1.25e-212	-	-	-	-	-	-	-	-
APPACOFM_04026	2.48e-96	-	-	-	-	-	-	-	-
APPACOFM_04027	1e-131	-	-	-	-	-	-	-	-
APPACOFM_04028	5.98e-105	-	-	-	-	-	-	-	-
APPACOFM_04029	1.39e-281	-	-	-	C	-	-	-	radical SAM domain protein
APPACOFM_04030	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
APPACOFM_04031	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
APPACOFM_04032	2.34e-141	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
APPACOFM_04033	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycosyl hydrolase family 20, catalytic domain
APPACOFM_04034	9.31e-137	-	-	-	S	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
APPACOFM_04035	0.0	-	-	-	P	ko:K16089	-	ko00000,ko02000	COG4771 Outer membrane receptor for ferrienterochelin and colicins
APPACOFM_04036	4.67e-71	-	-	-	-	-	-	-	-
APPACOFM_04037	0.0	-	-	-	P	ko:K16089	-	ko00000,ko02000	COG4771 Outer membrane receptor for ferrienterochelin and colicins
APPACOFM_04038	0.0	-	-	-	P	ko:K07085	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_04039	1.25e-207	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
APPACOFM_04040	1.59e-192	-	-	-	S	-	-	-	Calycin-like beta-barrel domain
APPACOFM_04041	1.15e-159	-	-	-	S	-	-	-	HmuY protein
APPACOFM_04042	0.0	hmuR	-	-	P	ko:K16089	-	ko00000,ko02000	COG4771 Outer membrane receptor for ferrienterochelin and colicins
APPACOFM_04043	0.0	cobN	6.6.1.2	-	H	ko:K02230	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	COG1429 Cobalamin biosynthesis protein CobN and related
APPACOFM_04044	0.0	cobN	6.6.1.2	-	H	ko:K02230	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	COG1429 Cobalamin biosynthesis protein CobN and related
APPACOFM_04045	6.31e-159	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_04046	2.6e-135	-	-	-	U	-	-	-	Psort location CytoplasmicMembrane, score 9.46
APPACOFM_04047	1.76e-68	-	-	-	S	-	-	-	Conserved protein
APPACOFM_04048	8.4e-51	-	-	-	-	-	-	-	-
APPACOFM_04050	7.79e-164	eda	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	KDPG and KHG aldolase
APPACOFM_04051	1.95e-248	-	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Kinase, PfkB family
APPACOFM_04052	5.17e-54	-	-	-	K	ko:K02529	-	ko00000,ko03000	Psort location Cytoplasmic, score
APPACOFM_04053	4.29e-160	-	-	-	K	ko:K02529	-	ko00000,ko03000	Psort location Cytoplasmic, score
APPACOFM_04054	0.0	uxaA	4.2.1.42, 4.2.1.7	-	G	ko:K01685,ko:K01708	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.96
APPACOFM_04055	7.44e-232	-	-	-	L	-	-	-	COG COG3547 Transposase and inactivated derivatives
APPACOFM_04056	0.0	-	-	-	P	-	-	-	TonB-dependent Receptor Plug Domain
APPACOFM_04057	8.11e-118	-	-	-	P	-	-	-	TonB-dependent Receptor Plug Domain
APPACOFM_04058	0.0	-	-	-	EGP	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_04059	3.96e-185	-	-	-	V	ko:K03543	-	ko00000,ko00002,ko02000	Auxiliary transport protein, membrane fusion protein (MFP) family protein
APPACOFM_04060	1.19e-294	-	-	-	MU	-	-	-	Psort location OuterMembrane, score
APPACOFM_04061	2.26e-94	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
APPACOFM_04062	3.31e-120	-	-	-	Q	-	-	-	membrane
APPACOFM_04063	5.33e-63	-	-	-	K	-	-	-	Winged helix DNA-binding domain
APPACOFM_04064	3.69e-251	creD	-	-	V	ko:K06143	-	ko00000	COG COG4452 Inner membrane protein involved in colicin E2 resistance
APPACOFM_04065	9.99e-21	creD	-	-	V	ko:K06143	-	ko00000	COG COG4452 Inner membrane protein involved in colicin E2 resistance
APPACOFM_04066	9.22e-135	-	-	-	-	-	-	-	-
APPACOFM_04067	2.05e-62	-	-	-	S	-	-	-	Protein of unknown function (DUF2089)
APPACOFM_04068	1.57e-107	-	-	-	E	-	-	-	Appr-1-p processing protein
APPACOFM_04069	3.22e-103	yvbK	2.3.1.82	-	K	ko:K03827,ko:K18815	-	br01600,ko00000,ko01000,ko01504	Psort location Cytoplasmic, score 8.96
APPACOFM_04070	2.08e-240	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
APPACOFM_04071	0.0	-	-	-	E	-	-	-	Peptidase, S9A B C family, catalytic domain protein
APPACOFM_04072	1.82e-183	-	-	-	E	-	-	-	Peptidase, S9A B C family, catalytic domain protein
APPACOFM_04073	3.72e-80	-	-	-	K	-	-	-	Transcriptional regulator, HxlR family
APPACOFM_04074	1.45e-124	-	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	DJ-1 PfpI family protein
APPACOFM_04075	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
APPACOFM_04076	2.16e-49	-	-	-	K	-	-	-	LytTr DNA-binding domain protein
APPACOFM_04077	3.02e-98	-	-	-	K	ko:K02477	-	ko00000,ko02022	LytTr DNA-binding domain protein
APPACOFM_04078	1.73e-247	-	-	-	T	-	-	-	Histidine kinase
APPACOFM_04079	2.25e-301	-	-	-	MU	-	-	-	Psort location OuterMembrane, score
APPACOFM_04080	0.0	-	-	-	V	-	-	-	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
APPACOFM_04081	7.83e-242	-	-	-	M	-	-	-	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
APPACOFM_04082	2.77e-290	mleN	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
APPACOFM_04084	1.87e-88	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
APPACOFM_04085	3.44e-237	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_04086	0.0	fucI	5.3.1.25, 5.3.1.3	-	G	ko:K01818	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Converts the aldose L-fucose into the corresponding ketose L-fuculose
APPACOFM_04087	1.44e-16	fucA	4.1.1.104	-	G	ko:K22130	-	ko00000,ko01000	L-fuculose-phosphate aldolase, aldolase class II family
APPACOFM_04088	1.71e-97	fucA	4.1.1.104	-	G	ko:K22130	-	ko00000,ko01000	L-fuculose-phosphate aldolase, aldolase class II family
APPACOFM_04089	0.0	fucK	2.7.1.5, 2.7.1.51	-	G	ko:K00848,ko:K00879	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
APPACOFM_04090	1.38e-89	-	5.1.3.32	-	G	ko:K03534	-	ko00000,ko01000	Psort location Cytoplasmic, score 8.96
APPACOFM_04091	8.04e-313	fucP	-	-	G	ko:K02429	-	ko00000,ko02000	L-fucose H symporter permease
APPACOFM_04092	9.58e-105	rpoE3	-	-	K	ko:K03088	-	ko00000,ko03021	RNA polymerase sigma-70 factor
APPACOFM_04093	1.39e-230	-	-	-	PT	-	-	-	Sigma factor regulatory protein, FecR PupR family
APPACOFM_04094	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_04095	1.82e-303	-	-	-	S	-	-	-	Susd and RagB outer membrane lipoprotein
APPACOFM_04096	2.16e-142	-	-	-	S	-	-	-	Putative glycoside hydrolase Family 18, chitinase_18
APPACOFM_04097	1.01e-256	-	-	-	G	-	-	-	Glycosyl hydrolases family 18
APPACOFM_04098	2.7e-133	-	-	-	G	-	-	-	Glycosyl hydrolases family 18
APPACOFM_04099	1.14e-231	-	-	-	S	-	-	-	Domain of unknown function (DUF4973)
APPACOFM_04101	0.0	-	-	-	T	-	-	-	helix_turn_helix, arabinose operon control protein
APPACOFM_04102	7.79e-142	-	-	-	S	-	-	-	Domain of unknown function (DUF4840)
APPACOFM_04103	0.0	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Psort location Periplasmic, score 9.44
APPACOFM_04104	7.28e-174	ydcV	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, permease protein
APPACOFM_04105	2.14e-176	-	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_04106	3.96e-247	potA	3.6.3.31	-	P	ko:K10112,ko:K11072,ko:K17324	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
APPACOFM_04107	2.51e-259	-	-	-	O	-	-	-	Antioxidant, AhpC TSA family
APPACOFM_04108	0.0	glgP	2.4.1.1, 2.4.1.11, 2.4.1.8	GH65,GT3,GT35	G	ko:K00688,ko:K00691,ko:K16153	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000,ko01003	COG0058 Glucan phosphorylase
APPACOFM_04109	1.49e-26	glgP	2.4.1.1, 2.4.1.11, 2.4.1.8	GH65,GT3,GT35	G	ko:K00688,ko:K00691,ko:K16153	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000,ko01003	COG0058 Glucan phosphorylase
APPACOFM_04110	0.0	-	2.4.1.11	GT3	G	ko:K00693	ko00500,ko01100,ko04151,ko04152,ko04910,ko04922,ko04931,map00500,map01100,map04151,map04152,map04910,map04922,map04931	ko00000,ko00001,ko01000,ko01003	Starch synthase
APPACOFM_04111	8.7e-95	ntpK	-	-	C	ko:K02124	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	COG COG0636 F0F1-type ATP synthase, subunit c Archaeal vacuolar-type H -ATPase, subunit K
APPACOFM_04112	0.0	-	-	-	C	ko:K02123	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	Belongs to the V-ATPase 116 kDa subunit family
APPACOFM_04113	5.05e-131	-	-	-	C	ko:K02120	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	Psort location Cytoplasmic, score 8.96
APPACOFM_04114	0.0	ntpB	-	-	C	ko:K02118	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	ATP synthase alpha beta family, nucleotide-binding domain protein
APPACOFM_04115	0.0	atpA	3.6.3.14, 3.6.3.15	-	C	ko:K02117	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
APPACOFM_04116	3.54e-193	-	-	-	C	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_04117	4.84e-106	-	-	-	C	ko:K02121	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	COG NOG11642 non supervised orthologous group
APPACOFM_04118	5.08e-87	-	-	-	-	-	-	-	-
APPACOFM_04119	1.87e-25	-	-	-	-	-	-	-	-
APPACOFM_04120	4.56e-78	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_04121	1.57e-171	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_04122	1.54e-184	cbiO	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score
APPACOFM_04126	1.31e-252	-	-	-	S	-	-	-	Clostripain family
APPACOFM_04127	1.94e-86	-	-	-	S	-	-	-	COG NOG31446 non supervised orthologous group
APPACOFM_04128	4.26e-119	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
APPACOFM_04129	5.16e-189	rpoD	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
APPACOFM_04130	0.0	htrA	-	-	O	-	-	-	Psort location Periplasmic, score
APPACOFM_04131	3.21e-266	ykfB	5.1.1.20, 5.1.1.3	-	M	ko:K01776,ko:K19802	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the mandelate racemase muconate lactonizing enzyme family
APPACOFM_04132	1.64e-238	ykfC	-	-	M	-	-	-	NlpC P60 family protein
APPACOFM_04133	1.8e-10	yihY	-	-	S	ko:K07058	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_04134	7.31e-267	yihY	-	-	S	ko:K07058	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_04135	4.99e-113	-	-	-	C	-	-	-	Nitroreductase family
APPACOFM_04136	1.65e-140	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	COG0307 Riboflavin synthase alpha chain
APPACOFM_04138	3.08e-19	-	-	-	T	-	-	-	GHKL domain
APPACOFM_04139	7.25e-153	-	-	-	T	-	-	-	GHKL domain
APPACOFM_04140	3.25e-154	-	-	-	K	-	-	-	Response regulator receiver domain protein
APPACOFM_04142	2.12e-155	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
APPACOFM_04143	5.87e-178	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
APPACOFM_04144	1.23e-115	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_04145	2.03e-272	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
APPACOFM_04146	9.72e-186	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	COG0226 ABC-type phosphate transport system, periplasmic component
APPACOFM_04147	0.0	glnS	6.1.1.18	-	J	ko:K01886	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glutamine--tRNA ligase
APPACOFM_04148	5.29e-274	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_04149	9.13e-151	dedA	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
APPACOFM_04150	2.46e-216	-	-	-	M	-	-	-	COG NOG19097 non supervised orthologous group
APPACOFM_04151	1.08e-113	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
APPACOFM_04152	1.08e-125	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_04153	3.26e-111	-	-	-	S	-	-	-	COG NOG14445 non supervised orthologous group
APPACOFM_04154	2.05e-159	yggS	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
APPACOFM_04155	8.37e-193	preA	1.3.98.1	-	F	ko:K00226	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dihydroorotate to orotate
APPACOFM_04156	1.82e-290	ybeZ_1	-	-	T	ko:K07175	-	ko00000	ATPase related to phosphate starvation-inducible protein PhoH
APPACOFM_04157	0.0	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Folylpolyglutamate synthase
APPACOFM_04158	3.88e-56	ridA	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	endoribonuclease L-PSP
APPACOFM_04159	1.53e-74	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.46
APPACOFM_04161	2.05e-132	rfbC	5.1.3.13	-	G	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
APPACOFM_04162	1.35e-219	tagO	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_04163	4.47e-145	-	-	-	S	ko:K07011	-	ko00000	Glycosyl transferase family 2
APPACOFM_04164	8.38e-65	-	-	-	S	ko:K08280	-	ko00000,ko01000,ko01005	Hexapeptide repeat of succinyl-transferase
APPACOFM_04165	6.94e-90	-	-	-	S	-	-	-	Glycosyltransferase like family 2
APPACOFM_04167	5.96e-150	-	-	-	M	-	-	-	Glycosyltransferase like family 2
APPACOFM_04168	1.02e-112	-	-	GT25	M	ko:K07270	-	ko00000	Glycosyltransferase family 25 (LPS biosynthesis protein)
APPACOFM_04169	4.73e-91	-	-	-	GM	ko:K19431	-	ko00000,ko01000	Polysaccharide pyruvyl transferase
APPACOFM_04170	3.93e-51	-	-	-	M	ko:K07282	-	ko00000	Bacterial capsule synthesis protein PGA_cap
APPACOFM_04172	2.03e-91	-	-	-	-	-	-	-	-
APPACOFM_04173	3.2e-162	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_04174	4.58e-180	-	-	-	M	-	-	-	Chain length determinant protein
APPACOFM_04175	0.0	kpsD	-	-	M	-	-	-	COG1596 Periplasmic protein involved in polysaccharide export
APPACOFM_04176	1.17e-84	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_04177	2.66e-132	-	-	-	K	-	-	-	KOW (Kyprides, Ouzounis, Woese) motif.
APPACOFM_04178	0.0	-	-	-	O	-	-	-	COG COG0457 FOG TPR repeat
APPACOFM_04179	1.82e-174	trmH	2.1.1.185	-	J	ko:K03218,ko:K03437	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
APPACOFM_04180	5.6e-190	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
APPACOFM_04181	1.14e-150	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
APPACOFM_04182	1.49e-230	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
APPACOFM_04183	4.6e-39	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
APPACOFM_04184	3.42e-187	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	COG0847 DNA polymerase III epsilon subunit and related 3'-5'
APPACOFM_04185	9.85e-261	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
APPACOFM_04186	4.55e-83	-	-	-	L	-	-	-	COG NOG19098 non supervised orthologous group
APPACOFM_04187	0.0	-	-	-	S	-	-	-	COG NOG25407 non supervised orthologous group
APPACOFM_04188	2.94e-187	lipB	3.1.4.55	-	S	ko:K06167	ko00440,map00440	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.96
APPACOFM_04189	2.63e-241	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
APPACOFM_04190	4.74e-208	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_04191	1.34e-232	ltd	-	-	M	-	-	-	NAD dependent epimerase dehydratase family
APPACOFM_04192	1.71e-283	kbl	2.3.1.29	-	H	ko:K00639	ko00260,map00260	ko00000,ko00001,ko01000,ko01007	Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA
APPACOFM_04193	2.07e-80	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
APPACOFM_04194	1.38e-112	ftnA	1.16.3.2	-	P	ko:K02217	-	ko00000,ko01000	Iron-storage protein
APPACOFM_04195	1.4e-282	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
APPACOFM_04196	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
APPACOFM_04197	2.59e-171	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Psort location CytoplasmicMembrane, score 7.88
APPACOFM_04198	8.17e-147	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	belongs to the PRA-CH family
APPACOFM_04199	1.33e-178	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
APPACOFM_04200	2.31e-173	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
APPACOFM_04201	3.1e-143	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
APPACOFM_04202	3.74e-206	purU	3.5.1.10	-	F	ko:K01433	ko00630,ko00670,map00630,map00670	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
APPACOFM_04205	5.56e-142	-	-	-	S	-	-	-	DJ-1/PfpI family
APPACOFM_04206	7.53e-203	-	-	-	S	-	-	-	aldo keto reductase family
APPACOFM_04208	4.68e-99	-	-	-	S	-	-	-	Pyridoxamine 5'-phosphate oxidase like
APPACOFM_04209	1.07e-209	-	-	-	K	-	-	-	methylphosphotriester-DNA alkyltransferase and transcriptional regulator (AraC XylS family)
APPACOFM_04210	1.23e-124	-	-	-	T	-	-	-	Cyclic nucleotide-monophosphate binding domain
APPACOFM_04211	3.99e-312	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_04212	9.08e-71	sugE	-	-	P	ko:K11741	-	ko00000,ko02000	Multidrug resistance protein, SMR family
APPACOFM_04213	3e-132	-	-	-	T	-	-	-	COG COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
APPACOFM_04214	4.02e-109	-	-	-	S	-	-	-	COG NOG17277 non supervised orthologous group
APPACOFM_04215	5.68e-254	-	-	-	M	-	-	-	ompA family
APPACOFM_04216	1.06e-80	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_04217	1.77e-279	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Cupin domain
APPACOFM_04218	2.28e-84	-	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
APPACOFM_04219	2.67e-219	-	-	-	C	-	-	-	Flavodoxin
APPACOFM_04220	1.75e-226	-	-	-	K	-	-	-	transcriptional regulator (AraC family)
APPACOFM_04221	2.76e-219	-	-	-	EG	-	-	-	EamA-like transporter family
APPACOFM_04222	2.17e-290	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	COG COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
APPACOFM_04223	6.72e-137	-	-	-	M	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_04224	4.59e-248	-	-	-	S	ko:K06889	-	ko00000	COG COG1073 Hydrolases of the alpha beta superfamily
APPACOFM_04225	1.88e-258	-	-	-	EGP	-	-	-	COG COG2814 Arabinose efflux permease
APPACOFM_04226	5.93e-172	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
APPACOFM_04227	0.0	dxs2	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
APPACOFM_04228	1.61e-197	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
APPACOFM_04229	1.38e-148	-	-	-	S	-	-	-	Membrane
APPACOFM_04230	5.29e-145	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
APPACOFM_04231	0.0	-	-	-	I	-	-	-	BadF/BadG/BcrA/BcrD ATPase family
APPACOFM_04232	1.91e-158	-	-	-	I	-	-	-	BadF/BadG/BcrA/BcrD ATPase family
APPACOFM_04233	0.0	-	-	-	M	ko:K08676	-	ko00000,ko01000,ko01002	Tricorn protease homolog
APPACOFM_04234	1.33e-227	-	-	-	H	-	-	-	Homocysteine S-methyltransferase
APPACOFM_04235	1.25e-203	-	2.5.1.105	-	S	ko:K06897	ko00790,map00790	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.96
APPACOFM_04236	1.97e-125	ogt	2.1.1.63	-	H	ko:K00567,ko:K10778	-	ko00000,ko01000,ko03000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
APPACOFM_04237	4.67e-132	ywqN	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_04238	2.3e-159	-	-	-	K	-	-	-	COG COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
APPACOFM_04239	0.0	-	-	-	M	-	-	-	COG NOG37029 non supervised orthologous group
APPACOFM_04240	6.07e-140	ycf	-	-	O	-	-	-	COG COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component
APPACOFM_04241	1.43e-290	ccs1	-	-	O	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_04242	2.3e-123	nrfA	1.7.2.2	-	C	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
APPACOFM_04243	6.5e-235	nrfA	1.7.2.2	-	C	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
APPACOFM_04244	7.04e-150	nrfH	-	-	C	ko:K15876	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002	COG COG3005 Nitrate TMAO reductases, membrane-bound tetraheme cytochrome c subunit
APPACOFM_04245	1.27e-115	-	-	-	S	-	-	-	Domain of unknown function (DUF4625)
APPACOFM_04246	4.31e-54	-	-	-	P	ko:K02014	-	ko00000,ko02000	COG COG1629 Outer membrane receptor proteins, mostly Fe transport
APPACOFM_04247	0.0	-	-	-	P	ko:K02014	-	ko00000,ko02000	COG COG1629 Outer membrane receptor proteins, mostly Fe transport
APPACOFM_04248	6.77e-71	-	-	-	-	-	-	-	-
APPACOFM_04249	5.9e-79	-	-	-	-	-	-	-	-
APPACOFM_04250	3.36e-20	-	-	-	H	-	-	-	COG NOG08812 non supervised orthologous group
APPACOFM_04251	3.23e-112	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_04252	1.88e-155	-	-	-	S	ko:K09807	-	ko00000	Protein of unknown function (DUF541)
APPACOFM_04253	1.85e-121	-	-	-	S	-	-	-	Protein of unknown function (DUF1062)
APPACOFM_04254	4.16e-196	-	-	-	S	-	-	-	RteC protein
APPACOFM_04255	4.22e-59	ycnE	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
APPACOFM_04256	1.02e-97	-	-	-	S	-	-	-	Pyridoxamine 5'-phosphate oxidase like
APPACOFM_04257	2.94e-197	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_04258	5.46e-136	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	COG0847 DNA polymerase III epsilon subunit and related 3'-5'
APPACOFM_04259	9.55e-287	uxuA	4.2.1.8	-	H	ko:K01686	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of D-mannonate
APPACOFM_04260	3.54e-188	uxuB	-	-	IQ	-	-	-	Oxidoreductase, short chain dehydrogenase reductase family protein
APPACOFM_04261	2.31e-244	-	-	-	K	ko:K02529	-	ko00000,ko03000	Psort location Cytoplasmic, score
APPACOFM_04262	5.01e-44	-	-	-	-	-	-	-	-
APPACOFM_04263	1.3e-26	-	-	-	S	-	-	-	Transglycosylase associated protein
APPACOFM_04264	9.54e-265	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
APPACOFM_04265	4.43e-270	fsr	-	-	G	ko:K08223	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_04266	0.0	-	-	-	E	ko:K21572	-	ko00000,ko02000	COG NOG25454 non supervised orthologous group
APPACOFM_04267	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_04268	7.85e-265	-	-	-	N	-	-	-	Psort location OuterMembrane, score
APPACOFM_04269	0.0	bioA	2.6.1.62	-	H	ko:K00833	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a
APPACOFM_04270	5.85e-274	bioF	2.3.1.29, 2.3.1.47	-	H	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	COG COG0156 7-keto-8-aminopelargonate synthetase and related enzymes
APPACOFM_04271	5.45e-153	-	3.1.1.85	-	S	ko:K09789	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Protein of unknown function (DUF452)
APPACOFM_04272	4.15e-187	bioC	2.1.1.197, 3.1.1.85	-	H	ko:K02169,ko:K09789	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway
APPACOFM_04273	6.65e-152	bioD	6.3.3.3	-	H	ko:K01935	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
APPACOFM_04274	0.0	-	-	-	T	-	-	-	Psort location CytoplasmicMembrane, score 7.88
APPACOFM_04275	2.93e-119	-	6.4.1.1	-	I	ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Biotin carboxyl carrier protein
APPACOFM_04276	0.0	-	6.3.4.14, 6.4.1.2, 6.4.1.3	-	I	ko:K01961,ko:K01965	ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase
APPACOFM_04277	0.0	-	2.1.3.15, 6.4.1.3	-	I	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	COG COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
APPACOFM_04278	7.05e-144	-	-	-	M	-	-	-	non supervised orthologous group
APPACOFM_04279	0.0	-	-	-	M	-	-	-	COG NOG23378 non supervised orthologous group
APPACOFM_04280	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
APPACOFM_04281	3.01e-65	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
APPACOFM_04282	1.2e-145	prfH	-	-	J	ko:K02839	-	ko00000,ko03012	RF-1 domain
APPACOFM_04283	0.0	rtcB_2	6.5.1.3	-	S	ko:K14415	-	ko00000,ko01000,ko03016	tRNA-splicing ligase RtcB
APPACOFM_04284	5.1e-109	trxA2	-	-	O	-	-	-	Psort location Cytoplasmic, score 9.26
APPACOFM_04285	9.1e-240	-	-	-	S	-	-	-	Radical SAM superfamily
APPACOFM_04286	4.41e-187	-	-	-	CG	-	-	-	glycosyl
APPACOFM_04287	8.87e-54	-	-	-	S	ko:K00389	-	ko00000	Domain of unknown function (DUF202)
APPACOFM_04288	1.31e-164	-	-	-	K	-	-	-	COG3279 Response regulator of the LytR AlgR family
APPACOFM_04289	1.77e-260	ypdA_4	-	-	T	-	-	-	Histidine kinase
APPACOFM_04290	1.78e-220	-	-	-	T	-	-	-	Histidine kinase
APPACOFM_04291	0.0	-	-	-	P	-	-	-	Carboxypeptidase regulatory-like domain
APPACOFM_04292	8.86e-55	-	-	-	-	-	-	-	-
APPACOFM_04293	5.41e-11	-	-	-	-	-	-	-	-
APPACOFM_04294	1.07e-61	-	-	-	-	-	-	-	-
APPACOFM_04295	1.16e-106	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.46
APPACOFM_04296	8.4e-130	-	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Psort location Cytoplasmic, score
APPACOFM_04297	5e-112	-	-	-	E	-	-	-	Acetyltransferase (GNAT) domain
APPACOFM_04298	4.47e-165	-	-	-	-	-	-	-	-
APPACOFM_04299	9.91e-07	-	-	-	-	-	-	-	-
APPACOFM_04300	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, permease protein
APPACOFM_04301	8.69e-163	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
APPACOFM_04302	1.34e-265	-	-	-	M	ko:K02005	-	ko00000	Efflux transporter, RND family, MFP subunit
APPACOFM_04303	8.36e-285	-	-	-	MU	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	outer membrane efflux protein
APPACOFM_04304	0.0	-	-	-	T	-	-	-	COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains
APPACOFM_04305	2.16e-283	-	-	-	T	-	-	-	COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation
APPACOFM_04306	4.63e-231	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_04307	4.33e-281	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
APPACOFM_04308	2.25e-105	-	-	-	K	-	-	-	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
APPACOFM_04309	0.0	-	-	-	F	-	-	-	Belongs to the D-alanine--D-alanine ligase family
APPACOFM_04310	8.88e-234	lolE_1	-	-	M	ko:K09808	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4591 ABC-type transport system, involved in lipoprotein release, permease component
APPACOFM_04311	7.09e-294	aspC	2.6.1.1, 2.6.1.2, 2.6.1.66	-	E	ko:K00812,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I II
APPACOFM_04312	2.93e-299	-	-	-	G	-	-	-	COG2407 L-fucose isomerase and related
APPACOFM_04313	1.87e-213	-	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.96
APPACOFM_04314	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
APPACOFM_04315	2.62e-198	-	-	-	S	-	-	-	COG NOG25193 non supervised orthologous group
APPACOFM_04316	3.9e-284	-	-	-	T	-	-	-	COG NOG06399 non supervised orthologous group
APPACOFM_04317	2.21e-157	srrA	-	-	K	ko:K07657,ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
APPACOFM_04318	0.0	-	2.7.13.3	-	T	ko:K02484,ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
APPACOFM_04319	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_04320	5.18e-222	-	-	-	CO	-	-	-	COG NOG24939 non supervised orthologous group
APPACOFM_04321	0.0	-	-	-	T	-	-	-	Domain of unknown function (DUF5074)
APPACOFM_04322	9.16e-276	-	-	-	T	-	-	-	Domain of unknown function (DUF5074)
APPACOFM_04323	1.03e-202	-	-	-	S	-	-	-	Cell surface protein
APPACOFM_04324	0.0	-	-	-	H	-	-	-	COG4206 Outer membrane cobalamin receptor protein
APPACOFM_04325	0.0	-	-	-	S	-	-	-	COG NOG23380 non supervised orthologous group
APPACOFM_04326	5.73e-142	-	-	-	S	-	-	-	Domain of unknown function (DUF4465)
APPACOFM_04327	0.0	tnaA	4.1.99.1	-	E	ko:K01667	ko00380,map00380	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.96
APPACOFM_04328	2.32e-67	-	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
APPACOFM_04329	5.14e-50	-	-	-	S	-	-	-	Divergent 4Fe-4S mono-cluster
APPACOFM_04330	1.38e-142	sfp	-	-	H	-	-	-	Belongs to the P-Pant transferase superfamily
APPACOFM_04331	1.8e-306	gldE	-	-	S	-	-	-	Gliding motility-associated protein GldE
APPACOFM_04332	5.6e-98	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
APPACOFM_04333	9.65e-257	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	COG1194 A G-specific DNA glycosylase
APPACOFM_04334	1.66e-56	hupA	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Belongs to the bacterial histone-like protein family
APPACOFM_04335	2.28e-53	rng	-	-	J	ko:K08301	-	ko00000,ko01000,ko03009,ko03019	S1 RNA binding domain
APPACOFM_04336	1.13e-285	rng	-	-	J	ko:K08301	-	ko00000,ko01000,ko03009,ko03019	S1 RNA binding domain
APPACOFM_04337	6.78e-193	-	-	-	M	-	-	-	COG2885 Outer membrane protein and related peptidoglycan-associated
APPACOFM_04338	1.06e-51	-	-	-	M	-	-	-	COG2885 Outer membrane protein and related peptidoglycan-associated
APPACOFM_04339	0.0	-	-	-	N	-	-	-	nuclear chromosome segregation
APPACOFM_04340	1.15e-151	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
APPACOFM_04341	8.05e-17	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
APPACOFM_04342	4.9e-264	-	-	-	M	-	-	-	COG2885 Outer membrane protein and related peptidoglycan-associated
APPACOFM_04343	9.66e-115	-	-	-	-	-	-	-	-
APPACOFM_04344	0.0	-	-	-	N	-	-	-	bacterial-type flagellum assembly
APPACOFM_04346	1.96e-223	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
APPACOFM_04347	1.08e-177	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_04348	1e-248	-	-	-	M	-	-	-	COG2885 Outer membrane protein and related peptidoglycan-associated
APPACOFM_04349	0.0	-	-	-	N	-	-	-	bacterial-type flagellum assembly
APPACOFM_04350	9.08e-224	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
APPACOFM_04351	9.11e-69	-	-	-	S	-	-	-	Domain of unknown function (DUF4248)
APPACOFM_04352	2.33e-155	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_04353	0.0	-	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
APPACOFM_04354	2.55e-105	-	-	-	L	-	-	-	DNA-binding protein
APPACOFM_04355	7.9e-55	-	-	-	-	-	-	-	-
APPACOFM_04356	2.09e-113	-	3.5.1.28	-	V	ko:K01447	-	ko00000,ko01000	Psort location Cytoplasmic, score 8.96
APPACOFM_04357	2.94e-48	-	-	-	K	-	-	-	Fic/DOC family
APPACOFM_04358	1.45e-216	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_04359	6.83e-224	-	-	-	I	-	-	-	Inositolphosphotransferase 1, involved in synthesis of mannose-(inositol-P)2-ceramide (M(IP)2C), which is the most abundant sphingolipid in cells, mutation confers resistance to the antifungals syringomycin E and DmAMP1 in some growth media
APPACOFM_04360	1.19e-153	pgsA1	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
APPACOFM_04361	1.7e-106	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
APPACOFM_04362	2.79e-112	pgpA	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_04363	0.0	ino1	5.5.1.4	-	I	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	ko00000,ko00001,ko01000	Inositol-3-phosphate synthase
APPACOFM_04364	0.0	-	-	-	M	-	-	-	COG NOG06397 non supervised orthologous group
APPACOFM_04365	1.65e-301	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
APPACOFM_04366	4.63e-316	-	-	-	T	ko:K02481	-	ko00000,ko02022	acetoacetate metabolism regulatory protein AtoC K07714
APPACOFM_04367	0.0	-	-	-	MU	-	-	-	Psort location OuterMembrane, score
APPACOFM_04368	0.0	-	-	-	T	-	-	-	Psort location CytoplasmicMembrane, score
APPACOFM_04369	2.87e-309	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score
APPACOFM_04370	4.36e-301	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_04371	4.66e-119	-	-	-	S	-	-	-	COG NOG30399 non supervised orthologous group
APPACOFM_04372	3.15e-153	ytrE_3	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 7.88
APPACOFM_04373	5.73e-283	-	-	-	M	ko:K02005	-	ko00000	Efflux transporter, RND family, MFP subunit
APPACOFM_04374	0.0	ndh	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase, FAD-containing subunit
APPACOFM_04375	1.33e-16	lytG	-	-	MNU	-	-	-	COG1705 Muramidase (flagellum-specific)
APPACOFM_04376	6.18e-182	lytG	-	-	MNU	-	-	-	COG1705 Muramidase (flagellum-specific)
APPACOFM_04377	7.97e-108	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
APPACOFM_04378	1.24e-197	-	-	-	K	-	-	-	COG COG2207 AraC-type DNA-binding domain-containing proteins
APPACOFM_04379	1.17e-132	ykgB	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.46
APPACOFM_04380	0.0	merA	-	-	C	ko:K21739	-	ko00000	COG COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
APPACOFM_04381	2.59e-221	-	-	-	S	-	-	-	COG COG0488 ATPase components of ABC transporters with duplicated ATPase domains
APPACOFM_04382	9.51e-37	-	-	-	S	-	-	-	COG COG0488 ATPase components of ABC transporters with duplicated ATPase domains
APPACOFM_04383	9.52e-198	nudC	3.6.1.22	-	L	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	ko00000,ko00001,ko01000	COG COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding
APPACOFM_04384	1.18e-138	-	-	-	T	-	-	-	COG COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
APPACOFM_04385	6.33e-241	oatA	-	-	I	-	-	-	Acyltransferase family
APPACOFM_04386	2.94e-282	-	-	-	S	ko:K07148	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_04387	0.0	pgcA	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II
APPACOFM_04388	0.0	-	-	-	M	-	-	-	Dipeptidase
APPACOFM_04389	0.0	-	-	-	M	-	-	-	Peptidase, M23 family
APPACOFM_04390	0.0	-	-	-	O	-	-	-	non supervised orthologous group
APPACOFM_04391	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_04392	1.61e-312	-	-	-	S	ko:K21572	-	ko00000,ko02000	COG NOG26865 non supervised orthologous group
APPACOFM_04393	3.19e-263	ald	1.4.1.1	-	C	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
APPACOFM_04394	2.46e-220	fabK	1.3.1.9	-	C	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	related to 2-nitropropane dioxygenase
APPACOFM_04395	1.69e-172	-	-	-	S	-	-	-	COG NOG28261 non supervised orthologous group
APPACOFM_04397	9.57e-127	-	-	-	S	-	-	-	COG NOG28799 non supervised orthologous group
APPACOFM_04398	3.7e-221	-	-	-	K	-	-	-	COG NOG25837 non supervised orthologous group
APPACOFM_04399	2.2e-123	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
APPACOFM_04400	1.91e-198	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NadC ModD family
APPACOFM_04401	1.43e-82	-	-	-	S	-	-	-	COG NOG32209 non supervised orthologous group
APPACOFM_04402	7.87e-111	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
APPACOFM_04403	5.07e-150	-	-	-	S	ko:K06950	-	ko00000	Psort location Cytoplasmic, score 8.96
APPACOFM_04404	1.46e-110	queF	1.7.1.13	-	H	ko:K09457	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
APPACOFM_04405	1.5e-138	queC	6.3.4.20	-	F	ko:K06920	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
APPACOFM_04406	2.68e-152	yhhQ	-	-	S	ko:K09125	-	ko00000	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
APPACOFM_04407	5.64e-59	marR	-	-	K	-	-	-	Winged helix DNA-binding domain
APPACOFM_04408	1.71e-131	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
APPACOFM_04409	0.0	-	-	-	P	-	-	-	Outer membrane protein beta-barrel family
APPACOFM_04410	6.46e-83	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2141)
APPACOFM_04411	6.55e-39	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
APPACOFM_04412	2.13e-66	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
APPACOFM_04413	0.0	-	-	-	S	-	-	-	COG NOG10142 non supervised orthologous group
APPACOFM_04414	0.0	-	-	-	I	ko:K06076	-	ko00000,ko02000	COG COG2067 Long-chain fatty acid transport protein
APPACOFM_04415	6.95e-238	ldhA	1.1.1.28	-	C	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
APPACOFM_04416	1.16e-30	-	-	-	S	ko:K06911	-	ko00000	Belongs to the pirin family
APPACOFM_04417	1.63e-120	-	-	-	S	ko:K06911	-	ko00000	Belongs to the pirin family
APPACOFM_04418	9.11e-182	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_04419	6.72e-265	-	-	-	S	ko:K03646	-	ko00000,ko02000	Domain of unknown function (DUF4468) with TBP-like fold
APPACOFM_04420	3.7e-92	gloA	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.96
APPACOFM_04421	1.41e-103	-	-	-	-	-	-	-	-
APPACOFM_04422	7.45e-33	-	-	-	-	-	-	-	-
APPACOFM_04423	3.1e-172	cypM_1	-	-	H	-	-	-	Methyltransferase domain protein
APPACOFM_04424	1.14e-135	-	-	-	CO	-	-	-	Redoxin family
APPACOFM_04426	3.74e-75	-	-	-	-	-	-	-	-
APPACOFM_04427	1.17e-164	-	-	-	-	-	-	-	-
APPACOFM_04428	4.71e-129	-	-	-	-	-	-	-	-
APPACOFM_04429	4.34e-188	-	-	-	K	-	-	-	YoaP-like
APPACOFM_04430	9.4e-105	-	-	-	-	-	-	-	-
APPACOFM_04432	3.79e-20	-	-	-	S	-	-	-	Fic/DOC family
APPACOFM_04433	4.8e-251	-	-	-	-	-	-	-	-
APPACOFM_04434	0.0	-	-	-	S	-	-	-	TonB-dependent Receptor Plug Domain
APPACOFM_04435	1.28e-191	-	-	-	S	-	-	-	TonB-dependent Receptor Plug Domain
APPACOFM_04438	5.7e-48	-	-	-	-	-	-	-	-
APPACOFM_04439	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
APPACOFM_04440	1.38e-259	tilS	6.3.4.19	-	D	ko:K04075	-	ko00000,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
APPACOFM_04441	8.74e-234	-	-	-	C	-	-	-	4Fe-4S binding domain
APPACOFM_04442	0.0	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
APPACOFM_04443	0.0	-	3.1.6.6	-	P	ko:K01133	-	ko00000,ko01000	COG COG3119 Arylsulfatase A and related enzymes
APPACOFM_04444	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
APPACOFM_04445	0.0	-	-	-	T	-	-	-	COG0642 Signal transduction histidine kinase
APPACOFM_04446	3.29e-297	-	-	-	V	-	-	-	MATE efflux family protein
APPACOFM_04447	6.22e-302	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
APPACOFM_04448	0.0	-	-	-	L	-	-	-	transposase activity
APPACOFM_04449	2.13e-231	-	-	-	L	-	-	-	COG COG3547 Transposase and inactivated derivatives
APPACOFM_04450	5.55e-212	-	-	-	O	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_04451	4.7e-193	ycf	-	-	O	-	-	-	COG COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component
APPACOFM_04452	0.0	ccp	1.11.1.5	-	C	ko:K00428	-	ko00000,ko01000	Psort location Periplasmic, score
APPACOFM_04453	1.11e-207	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
APPACOFM_04454	1.39e-113	-	-	-	M	ko:K07282	-	ko00000	Bacterial capsule synthesis protein
APPACOFM_04455	1.89e-110	-	-	-	M	ko:K07282	-	ko00000	Bacterial capsule synthesis protein
APPACOFM_04457	5.83e-51	-	-	-	KT	-	-	-	PspC domain protein
APPACOFM_04458	0.0	dnaX	2.7.7.7	-	H	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
APPACOFM_04459	3.57e-62	-	-	-	D	-	-	-	Septum formation initiator
APPACOFM_04460	1.66e-73	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
APPACOFM_04461	2.76e-126	-	-	-	M	ko:K06142	-	ko00000	membrane
APPACOFM_04462	0.0	pepD_1	-	-	E	ko:K01270	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Psort location Cytoplasmic, score 8.96
APPACOFM_04463	1.06e-259	-	-	-	S	-	-	-	Endonuclease Exonuclease phosphatase family
APPACOFM_04464	2.19e-125	-	-	-	K	ko:K03088	-	ko00000,ko03021	ECF sigma factor
APPACOFM_04465	5.72e-238	-	-	-	PT	-	-	-	Domain of unknown function (DUF4974)
APPACOFM_04466	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_04467	0.0	-	-	-	E	ko:K21572	-	ko00000,ko02000	Pfam:SusD
APPACOFM_04468	1.36e-93	-	-	-	E	ko:K21572	-	ko00000,ko02000	Pfam:SusD
APPACOFM_04469	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 20, catalytic domain
APPACOFM_04470	0.0	-	3.1.6.1	-	P	ko:K01130	ko00140,ko00600,map00140,map00600	ko00000,ko00001,ko01000	Arylsulfatase
APPACOFM_04471	2.82e-280	ybdG_1	-	-	M	ko:K16053	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_04472	0.0	-	-	-	P	-	-	-	COG COG3119 Arylsulfatase A and related enzymes
APPACOFM_04473	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	F5 8 type C domain protein
APPACOFM_04474	0.0	lacZ	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	COG3250 Beta-galactosidase beta-glucuronidase
APPACOFM_04475	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycosyl hydrolase family 20, catalytic domain
APPACOFM_04476	0.0	betC_2	-	-	P	-	-	-	COG COG3119 Arylsulfatase A and related enzymes
APPACOFM_04477	0.0	-	-	-	G	-	-	-	Domain of unknown function (DUF5014)
APPACOFM_04478	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	SusD family
APPACOFM_04479	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_04480	0.0	-	-	-	G	-	-	-	Glycosyl hydrolases family 18
APPACOFM_04481	3.9e-96	hddC	-	-	JM	-	-	-	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon)
APPACOFM_04482	2.88e-51	hddC	-	-	JM	-	-	-	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon)
APPACOFM_04483	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_04484	0.0	-	-	-	T	-	-	-	COG COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
APPACOFM_04485	3.56e-29	-	3.1.6.1	-	P	ko:K01130	ko00140,ko00600,map00140,map00600	ko00000,ko00001,ko01000	Arylsulfatase
APPACOFM_04486	0.0	-	3.1.6.1	-	P	ko:K01130	ko00140,ko00600,map00140,map00600	ko00000,ko00001,ko01000	Arylsulfatase
APPACOFM_04488	7.53e-150	-	-	-	L	-	-	-	VirE N-terminal domain protein
APPACOFM_04489	0.0	-	-	-	L	-	-	-	COG NOG25561 non supervised orthologous group
APPACOFM_04490	5.04e-47	-	-	-	S	-	-	-	Domain of unknown function (DUF4248)
APPACOFM_04491	2.14e-99	-	-	-	L	-	-	-	regulation of translation
APPACOFM_04493	8.32e-67	-	3.5.1.28	-	V	ko:K01447	-	ko00000,ko01000	Psort location Cytoplasmic, score 8.96
APPACOFM_04494	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_04495	3.38e-135	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score
APPACOFM_04496	5.05e-192	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
APPACOFM_04497	1.61e-107	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
APPACOFM_04498	2.39e-94	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
APPACOFM_04500	7.59e-245	-	-	-	M	-	-	-	Glycosyltransferase like family 2
APPACOFM_04501	4.84e-168	-	-	GT25	M	ko:K07270	-	ko00000	Glycosyltransferase family 25 (LPS biosynthesis protein)
APPACOFM_04502	9.91e-287	-	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
APPACOFM_04503	9.1e-62	ispD	1.1.1.405, 2.7.7.40, 2.7.7.60	-	M	ko:K00991,ko:K21681	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
APPACOFM_04504	1.52e-182	ispD	1.1.1.405, 2.7.7.40, 2.7.7.60	-	M	ko:K00991,ko:K21681	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
APPACOFM_04505	4.22e-42	ispD	1.1.1.405, 2.7.7.40, 2.7.7.60	-	M	ko:K00991,ko:K21681	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
APPACOFM_04506	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_04507	2.44e-245	-	-	-	M	-	-	-	Chain length determinant protein
APPACOFM_04508	0.0	kpsD	-	-	M	-	-	-	COG1596 Periplasmic protein involved in polysaccharide export
APPACOFM_04509	2.27e-134	-	-	-	K	-	-	-	COG NOG19120 non supervised orthologous group
APPACOFM_04510	2.73e-146	-	-	-	L	-	-	-	COG NOG21178 non supervised orthologous group
APPACOFM_04511	6.04e-71	-	-	-	L	-	-	-	COG NOG21178 non supervised orthologous group
APPACOFM_04512	1.84e-155	tal	2.2.1.2	-	F	ko:K00616,ko:K08314	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
APPACOFM_04513	1.97e-257	fbaB	4.1.2.13	-	G	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	COG COG1830 DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes
APPACOFM_04514	8.42e-185	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
APPACOFM_04515	0.0	-	-	-	T	-	-	-	Psort location CytoplasmicMembrane, score 7.88
APPACOFM_04516	0.0	modF	-	-	P	ko:K05776	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC molybdenum transporter, ATP-binding subunit modF
APPACOFM_04517	0.0	pulA	3.2.1.41	CBM48,GH13	G	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
APPACOFM_04518	2.19e-130	ruvC	3.1.22.4	-	L	ko:K01159	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
APPACOFM_04519	2.92e-70	-	-	-	S	-	-	-	COG NOG30624 non supervised orthologous group
APPACOFM_04521	1.44e-12	-	-	-	-	-	-	-	-
APPACOFM_04522	8.23e-123	-	-	-	FT	-	-	-	Response regulator, receiver
APPACOFM_04523	2.46e-64	-	-	-	KT	-	-	-	RESPONSE REGULATOR receiver
APPACOFM_04524	4.48e-267	-	-	-	T	-	-	-	Histidine kinase
APPACOFM_04527	8.41e-157	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_04530	1.37e-46	-	-	-	-	-	-	-	-
APPACOFM_04531	2.02e-121	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_04533	4.22e-47	-	-	-	-	-	-	-	-
APPACOFM_04535	6.83e-27	-	-	-	-	-	-	-	-
APPACOFM_04536	3.25e-39	-	-	-	G	ko:K21571	-	ko00000	Fibronectin type 3 domain
APPACOFM_04539	3.63e-124	-	-	-	-	-	-	-	-
APPACOFM_04540	5.68e-56	-	-	-	-	-	-	-	-
APPACOFM_04541	1.15e-59	-	-	-	S	-	-	-	KAP family P-loop domain
APPACOFM_04543	4.22e-58	-	-	-	-	-	-	-	-
APPACOFM_04544	1.53e-43	-	-	-	V	ko:K07451	-	ko00000,ko01000,ko02048	HNH endonuclease
APPACOFM_04545	3e-72	-	-	-	S	-	-	-	FRG
APPACOFM_04546	9.99e-154	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
APPACOFM_04547	2.95e-51	-	-	-	M	-	-	-	self proteolysis
APPACOFM_04548	1.2e-105	-	-	-	L	-	-	-	DNA photolyase activity
APPACOFM_04551	2.92e-138	-	-	-	-	-	-	-	-
APPACOFM_04553	1.65e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF3853)
APPACOFM_04555	8.5e-303	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_04556	1.61e-178	-	-	-	S	-	-	-	hydrolases of the HAD superfamily
APPACOFM_04557	5.79e-43	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_04558	1.67e-249	-	-	-	M	-	-	-	Gram-negative bacterial TonB protein C-terminal
APPACOFM_04559	2.76e-247	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
APPACOFM_04560	2.5e-297	-	-	-	EGP	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_04561	7.78e-165	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
APPACOFM_04562	3.7e-297	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Psort location Cytoplasmic, score
APPACOFM_04563	5.22e-130	-	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	NMT1/THI5 like
APPACOFM_04564	3.42e-43	-	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	NMT1/THI5 like
APPACOFM_04565	1.96e-251	-	-	-	P	-	-	-	phosphate-selective porin O and P
APPACOFM_04566	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat protein
APPACOFM_04567	5.15e-136	maf	-	-	D	ko:K06287	-	ko00000	COG0424 Nucleotide-binding protein implicated in inhibition of septum formation
APPACOFM_04568	1.46e-123	kdsC	3.1.3.45	-	S	ko:K03270	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family
APPACOFM_04569	1.18e-183	-	-	-	S	-	-	-	NADP oxidoreductase coenzyme F420-dependent
APPACOFM_04570	3.12e-68	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
APPACOFM_04571	3.22e-120	-	-	-	C	-	-	-	Nitroreductase family
APPACOFM_04572	1.39e-129	cah	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
APPACOFM_04573	0.0	-	-	-	E	ko:K21572	-	ko00000,ko02000	SusD family
APPACOFM_04574	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_04575	4.4e-245	-	-	-	V	-	-	-	COG NOG22551 non supervised orthologous group
APPACOFM_04576	2.75e-91	mce	5.1.99.1	-	E	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.96
APPACOFM_04577	0.0	mmdA	-	-	I	-	-	-	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
APPACOFM_04578	4.4e-216	-	-	-	C	-	-	-	Lamin Tail Domain
APPACOFM_04579	1.3e-78	mmdC	-	-	I	-	-	-	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
APPACOFM_04580	1.27e-269	oadB	4.1.1.3	-	C	ko:K01572	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	sodium ion-translocating decarboxylase, beta subunit
APPACOFM_04581	1.06e-311	-	-	-	S	-	-	-	Tetratricopeptide repeat protein
APPACOFM_04582	6.71e-241	fba	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
APPACOFM_04583	4.78e-55	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
APPACOFM_04584	4.21e-197	-	-	-	M	-	-	-	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
APPACOFM_04585	0.0	-	-	-	V	-	-	-	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
APPACOFM_04586	1.4e-300	-	-	-	MU	-	-	-	Psort location OuterMembrane, score
APPACOFM_04587	3.28e-194	-	4.1.1.3	-	C	ko:K01572	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	sodium ion-translocating decarboxylase, beta subunit
APPACOFM_04588	3.21e-72	-	4.1.1.3	-	C	ko:K01572	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	sodium ion-translocating decarboxylase, beta subunit
APPACOFM_04589	0.0	cfiA	6.4.1.1	-	C	ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	COG5016 Pyruvate oxaloacetate carboxyltransferase
APPACOFM_04590	1.36e-46	-	4.1.1.3	-	C	ko:K01573	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	Sodium pump decarboxylase gamma subunit
APPACOFM_04591	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_04593	8.8e-149	-	-	-	L	-	-	-	VirE N-terminal domain protein
APPACOFM_04594	0.0	-	-	-	L	-	-	-	COG NOG25561 non supervised orthologous group
APPACOFM_04595	3.54e-47	-	-	-	S	-	-	-	Domain of unknown function (DUF4248)
APPACOFM_04596	2.14e-99	-	-	-	L	-	-	-	regulation of translation
APPACOFM_04598	2.94e-101	-	3.5.1.28	-	V	ko:K01447	-	ko00000,ko01000	Psort location Cytoplasmic, score 8.96
APPACOFM_04599	7.31e-65	-	-	-	S	ko:K07075	-	ko00000	Nucleotidyltransferase domain
APPACOFM_04600	9.93e-155	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score
APPACOFM_04601	2.51e-194	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
APPACOFM_04603	1.17e-249	-	-	-	-	-	-	-	-
APPACOFM_04604	1.41e-285	-	-	-	M	-	-	-	Glycosyl transferases group 1
APPACOFM_04605	5.16e-115	kdsC	2.7.7.43, 2.7.7.92, 3.1.3.103	-	M	ko:K21055,ko:K21749	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family
APPACOFM_04606	1.89e-253	neuB	2.5.1.132	-	M	ko:K21279	-	ko00000,ko01000	Psort location Cytoplasmic, score 8.96
APPACOFM_04607	1.9e-177	-	2.7.7.92	-	M	ko:K07257,ko:K21750	-	ko00000,ko01000	Psort location Cytoplasmic, score 8.96
APPACOFM_04608	2.85e-64	-	-	-	M	-	-	-	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
APPACOFM_04609	2.36e-214	-	-	-	M	-	-	-	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
APPACOFM_04610	5.59e-292	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_04612	1.62e-279	phnW	2.6.1.37	-	E	ko:K03430,ko:K09469	ko00440,ko01100,ko01120,map00440,map01100,map01120	ko00000,ko00001,ko01000,ko01007	Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily
APPACOFM_04613	4.13e-278	aepY	4.1.1.82	-	C	ko:K09459	ko00440,ko01100,ko01120,ko01130,map00440,map01100,map01120,map01130	ko00000,ko00001,ko01000	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
APPACOFM_04614	3.84e-316	aepX	2.7.7.15, 2.7.7.39, 5.4.2.9	-	GIM	ko:K00968,ko:K00980,ko:K01841	ko00440,ko00564,ko01100,ko01120,ko01130,ko05231,map00440,map00564,map01100,map01120,map01130,map05231	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate phosphomutase
APPACOFM_04615	4.86e-175	-	-	-	M	-	-	-	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
APPACOFM_04616	4.82e-256	-	-	-	M	-	-	-	Chain length determinant protein
APPACOFM_04617	0.0	kpsD	-	-	M	-	-	-	COG1596 Periplasmic protein involved in polysaccharide export
APPACOFM_04618	3.92e-135	-	-	-	K	-	-	-	COG NOG19120 non supervised orthologous group
APPACOFM_04619	1.56e-230	-	-	-	L	-	-	-	COG NOG21178 non supervised orthologous group
APPACOFM_04620	2.43e-181	-	-	-	PT	-	-	-	FecR protein
APPACOFM_04621	5.11e-133	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70, region 4
APPACOFM_04622	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
APPACOFM_04623	2.09e-211	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
APPACOFM_04624	5.87e-127	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_04625	2.05e-147	-	-	-	E	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_04626	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate
APPACOFM_04627	0.0	-	-	-	T	-	-	-	Psort location CytoplasmicMembrane, score
APPACOFM_04628	2.67e-125	chrA	-	-	P	ko:K07240	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score
APPACOFM_04629	1.68e-122	-	-	-	P	ko:K07240	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_04630	0.0	yngK	-	-	S	-	-	-	lipoprotein YddW precursor
APPACOFM_04631	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
APPACOFM_04632	0.0	uvrA1	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
APPACOFM_04634	6.82e-114	-	-	-	MU	-	-	-	COG NOG29365 non supervised orthologous group
APPACOFM_04635	2.87e-30	-	-	-	S	-	-	-	COG NOG34202 non supervised orthologous group
APPACOFM_04636	0.0	cstA	-	-	T	ko:K06200	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_04637	0.0	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
APPACOFM_04638	0.0	yngK	-	-	S	-	-	-	lipoprotein YddW precursor K01189
APPACOFM_04639	2.41e-84	-	-	-	L	ko:K07483	-	ko00000	COG2963 Transposase and inactivated derivatives
APPACOFM_04640	1.77e-177	-	-	-	L	-	-	-	Integrase core domain
APPACOFM_04641	1.25e-225	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_04642	5.11e-275	-	-	-	S	ko:K07133	-	ko00000	ATPase (AAA superfamily)
APPACOFM_04643	0.0	nifJ	1.2.7.1	-	C	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
APPACOFM_04644	1e-35	-	-	-	-	-	-	-	-
APPACOFM_04645	4.71e-201	opuAC	-	-	E	ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, QAT family
APPACOFM_04646	7.14e-191	opuAB	-	-	P	ko:K02001	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine transport system, permease
APPACOFM_04647	5.27e-280	proV	3.6.3.32	-	S	ko:K02000	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	IMP dehydrogenase activity
APPACOFM_04648	1.22e-282	-	-	-	S	-	-	-	Pfam:DUF2029
APPACOFM_04649	3.96e-75	ogt	2.1.1.63	-	L	ko:K00567,ko:K07443	-	ko00000,ko01000,ko03400	6-O-methylguanine DNA methyltransferase, DNA binding domain
APPACOFM_04650	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
APPACOFM_04651	5.05e-197	-	-	-	S	-	-	-	protein conserved in bacteria
APPACOFM_04652	7.44e-232	-	-	-	L	-	-	-	COG COG3547 Transposase and inactivated derivatives
APPACOFM_04653	1.54e-215	ydjH_1	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family
APPACOFM_04654	1.01e-272	-	-	-	G	-	-	-	Transporter, major facilitator family protein
APPACOFM_04655	0.0	sacC	3.2.1.80	-	G	ko:K03332	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
APPACOFM_04656	0.0	-	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	hydrolase family 32
APPACOFM_04657	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4960)
APPACOFM_04658	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	Pfam:SusD
APPACOFM_04659	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_04660	1.09e-226	lacX	-	-	G	-	-	-	COG COG2017 Galactose mutarotase and related enzymes
APPACOFM_04661	0.0	sacC	3.2.1.80	-	G	ko:K03332	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
APPACOFM_04662	0.0	-	-	-	S	-	-	-	TROVE domain
APPACOFM_04663	7.03e-246	-	-	-	K	-	-	-	WYL domain
APPACOFM_04664	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 2 family
APPACOFM_04665	0.0	-	-	-	G	-	-	-	cog cog3537
APPACOFM_04666	0.0	-	-	-	T	-	-	-	COG NOG26059 non supervised orthologous group
APPACOFM_04667	0.0	-	-	-	N	-	-	-	Leucine rich repeats (6 copies)
APPACOFM_04668	0.0	-	-	-	-	-	-	-	-
APPACOFM_04669	0.0	-	-	-	S	-	-	-	Susd and RagB outer membrane lipoprotein
APPACOFM_04670	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_04671	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF5010)
APPACOFM_04672	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 2 family
APPACOFM_04673	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 2 family
APPACOFM_04674	0.0	-	3.2.1.51	GH95	G	ko:K15923	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65, N-terminal domain
APPACOFM_04675	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Psort location Periplasmic, score
APPACOFM_04676	0.0	-	3.1.1.53	-	G	ko:K05970	-	ko00000,ko01000	Glycosyl hydrolase family 2, sugar binding domain protein
APPACOFM_04677	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Psort location Periplasmic, score 9.44
APPACOFM_04678	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 43 family
APPACOFM_04679	2e-204	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_04680	0.0	nhaS3	-	-	P	-	-	-	Sodium/hydrogen exchanger family
APPACOFM_04681	6.67e-120	-	-	-	S	-	-	-	COG NOG28134 non supervised orthologous group
APPACOFM_04682	2.43e-273	-	-	-	I	-	-	-	COG NOG24984 non supervised orthologous group
APPACOFM_04683	0.0	-	-	-	S	-	-	-	COG NOG26034 non supervised orthologous group
APPACOFM_04684	6.49e-272	nanM	-	-	S	-	-	-	COG NOG23382 non supervised orthologous group
APPACOFM_04685	1.08e-69	-	-	-	S	-	-	-	Domain of unknown function (DUF4907)
APPACOFM_04687	1.18e-294	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
APPACOFM_04688	5.2e-167	-	-	-	K	-	-	-	Response regulator receiver domain protein
APPACOFM_04689	1.21e-286	-	-	-	T	-	-	-	Sensor histidine kinase
APPACOFM_04690	6.54e-205	-	-	-	K	-	-	-	transcriptional regulator (AraC family)
APPACOFM_04691	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4925)
APPACOFM_04692	0.0	-	-	-	M	ko:K02014	-	ko00000,ko02000	Psort location OuterMembrane, score 10.00
APPACOFM_04693	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
APPACOFM_04694	0.0	-	-	-	T	-	-	-	COG0642 Signal transduction histidine kinase
APPACOFM_04695	0.0	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
APPACOFM_04696	2.93e-165	-	-	-	S	-	-	-	Psort location OuterMembrane, score 9.52
APPACOFM_04697	4.9e-205	etfB	-	-	C	ko:K03521	-	ko00000	COG2086 Electron transfer flavoprotein beta subunit
APPACOFM_04698	1.08e-244	etfA	-	-	C	ko:K03522	-	ko00000,ko04147	Psort location Cytoplasmic, score 8.96
APPACOFM_04699	0.0	acd	-	-	C	-	-	-	Acyl-CoA dehydrogenase, C-terminal domain
APPACOFM_04700	4.65e-265	-	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Psort location CytoplasmicMembrane, score
APPACOFM_04701	8.62e-31	-	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Psort location CytoplasmicMembrane, score
APPACOFM_04702	3.86e-41	-	-	-	-	-	-	-	-
APPACOFM_04703	0.0	-	-	-	C	-	-	-	Domain of unknown function (DUF4132)
APPACOFM_04704	1.83e-111	msrC	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.96
APPACOFM_04705	3.55e-69	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_04706	6.86e-184	dnaJ2	-	-	O	ko:K03686,ko:K05516	-	ko00000,ko03029,ko03036,ko03110	Psort location Cytoplasmic, score
APPACOFM_04707	9.75e-60	eptA	-	-	S	-	-	-	lipid A phosphoethanolamine transferase, associated with polymyxin resistance
APPACOFM_04708	0.0	eptA	-	-	S	-	-	-	lipid A phosphoethanolamine transferase, associated with polymyxin resistance
APPACOFM_04709	6.37e-301	-	-	-	M	-	-	-	COG NOG06295 non supervised orthologous group
APPACOFM_04710	1.49e-250	ltaE	4.1.2.48	-	E	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.96
APPACOFM_04711	1.71e-78	-	-	-	-	-	-	-	-
APPACOFM_04712	4.11e-123	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
APPACOFM_04713	1.06e-90	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.46
APPACOFM_04714	2.13e-48	-	-	-	S	-	-	-	COG NOG33517 non supervised orthologous group
APPACOFM_04716	0.0	poxB	1.2.5.1, 2.2.1.6	-	C	ko:K00156,ko:K01652	ko00290,ko00620,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
APPACOFM_04717	1.87e-210	-	-	-	S	-	-	-	Predicted membrane protein (DUF2157)
APPACOFM_04718	5.19e-205	-	-	-	S	-	-	-	Domain of unknown function (DUF4401)
APPACOFM_04719	1.11e-113	-	-	-	S	-	-	-	GDYXXLXY protein
APPACOFM_04720	5.63e-222	-	-	-	M	-	-	-	COG2885 Outer membrane protein and related peptidoglycan-associated
APPACOFM_04721	1.08e-129	-	-	-	S	-	-	-	PFAM NLP P60 protein
APPACOFM_04722	3.78e-220	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
APPACOFM_04723	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_04724	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
APPACOFM_04725	3.78e-57	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
APPACOFM_04726	1.01e-250	-	-	-	S	-	-	-	COG NOG25022 non supervised orthologous group
APPACOFM_04727	4.97e-144	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
APPACOFM_04728	0.0	-	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.96
APPACOFM_04729	3.89e-22	-	-	-	-	-	-	-	-
APPACOFM_04730	0.0	-	-	-	C	-	-	-	4Fe-4S binding domain protein
APPACOFM_04731	7.11e-253	hydE	2.8.1.6	-	C	ko:K01012	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Iron-only hydrogenase maturation rSAM protein HydE
APPACOFM_04732	0.0	hydG	4.1.99.19	-	C	ko:K03150	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Iron-only hydrogenase maturation rSAM protein HydG
APPACOFM_04733	2.19e-291	hydF	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_04734	0.0	-	-	-	EU	-	-	-	Peptidase, S9A B C family, catalytic domain protein
APPACOFM_04735	0.0	-	-	-	S	-	-	-	phospholipase Carboxylesterase
APPACOFM_04736	0.0	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Psort location Cytoplasmic, score
APPACOFM_04737	5.87e-156	-	-	-	S	ko:K06973	-	ko00000	neutral zinc metallopeptidase
APPACOFM_04738	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
APPACOFM_04739	5.9e-316	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
APPACOFM_04740	7.33e-112	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
APPACOFM_04741	1.19e-157	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_04742	0.0	-	3.4.14.4	-	S	ko:K01277	-	ko00000,ko01000,ko01002	Peptidase family M49
APPACOFM_04743	3.16e-102	-	-	-	K	-	-	-	transcriptional regulator (AraC
APPACOFM_04744	0.0	recQ3	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
APPACOFM_04745	9.09e-260	-	-	-	M	-	-	-	Acyltransferase family
APPACOFM_04746	3.32e-60	-	-	-	S	-	-	-	COG COG0457 FOG TPR repeat
APPACOFM_04747	5.35e-220	cysK	2.5.1.47	-	E	ko:K01738,ko:K12339	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
APPACOFM_04748	0.0	ltaS2	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score
APPACOFM_04749	7.78e-165	ybjG	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_04750	1.36e-157	-	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
APPACOFM_04751	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4784)
APPACOFM_04752	1.83e-259	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
APPACOFM_04753	0.0	leuA_1	2.3.1.182	-	E	ko:K09011	ko00290,ko00660,ko01100,ko01210,ko01230,map00290,map00660,map01100,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the alpha-IPM synthase homocitrate synthase family
APPACOFM_04754	4.22e-143	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
APPACOFM_04755	0.0	leuC	4.2.1.33, 4.2.1.35	-	H	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
APPACOFM_04756	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
APPACOFM_04757	4.22e-27	-	-	-	-	-	-	-	-
APPACOFM_04760	0.0	-	3.2.1.20	GH31	M	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG NOG06228 non supervised orthologous group
APPACOFM_04761	0.0	bglX	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	glycosyl hydrolase, family 3
APPACOFM_04762	1.41e-243	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
APPACOFM_04763	2.69e-140	-	-	-	M	ko:K21572	-	ko00000,ko02000	SusD family
APPACOFM_04764	0.0	-	-	-	M	ko:K21572	-	ko00000,ko02000	SusD family
APPACOFM_04765	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_04766	8.22e-25	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_04767	2.84e-239	-	-	-	PT	-	-	-	Sigma factor regulatory protein, FecR PupR family
APPACOFM_04768	4.38e-134	-	-	-	K	ko:K03088	-	ko00000,ko03021	RNA polymerase sigma-70 factor
APPACOFM_04769	3.49e-244	-	-	-	G	-	-	-	Glycosyl hydrolase family 92
APPACOFM_04770	2.4e-300	-	-	-	G	-	-	-	Glycosyl hydrolase family 92
APPACOFM_04771	0.0	sppA	-	-	OU	ko:K04773	-	ko00000,ko01000,ko01002	signal peptide peptidase SppA, 67K type
APPACOFM_04772	4.33e-283	lpxK	2.7.1.130	-	F	ko:K00912	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)
APPACOFM_04773	1.24e-192	deoD	2.4.2.1	-	F	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
APPACOFM_04774	6.3e-251	thiL	2.7.4.16	-	H	ko:K00946	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
APPACOFM_04776	1.67e-106	-	-	-	G	-	-	-	Glycosyl hydrolase
APPACOFM_04777	5.49e-191	-	-	-	G	-	-	-	Glycosyl hydrolase
APPACOFM_04779	1.72e-74	cspG	-	-	K	-	-	-	Cold-shock DNA-binding domain protein
APPACOFM_04781	4.48e-257	rhlE	3.6.4.13	-	JKL	ko:K11927	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Belongs to the DEAD box helicase family
APPACOFM_04782	2.28e-257	-	-	-	S	-	-	-	Nitronate monooxygenase
APPACOFM_04783	2.23e-65	-	-	-	S	-	-	-	COG COG0724 RNA-binding proteins (RRM domain)
APPACOFM_04784	8.69e-183	-	-	-	K	-	-	-	COG NOG38984 non supervised orthologous group
APPACOFM_04785	7.33e-141	-	-	-	S	-	-	-	COG NOG23385 non supervised orthologous group
APPACOFM_04786	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	COG COG3973 Superfamily I DNA and RNA helicases
APPACOFM_04787	2.37e-220	-	-	-	L	-	-	-	Integrase core domain
APPACOFM_04788	1.81e-78	-	-	-	-	-	-	-	-
APPACOFM_04789	0.0	-	-	-	S	-	-	-	response regulator aspartate phosphatase
APPACOFM_04790	3.89e-90	-	-	-	-	-	-	-	-
APPACOFM_04791	5.64e-286	-	-	-	MO	-	-	-	Bacterial group 3 Ig-like protein
APPACOFM_04792	8.76e-52	-	-	-	S	ko:K03744	-	ko00000	LemA family
APPACOFM_04793	5.36e-219	-	-	-	S	-	-	-	Protein of unknown function (DUF3137)
APPACOFM_04794	1.31e-163	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_04795	5.66e-174	-	-	-	V	-	-	-	COG0534 Na -driven multidrug efflux pump
APPACOFM_04796	1.38e-99	-	-	-	V	-	-	-	COG0534 Na -driven multidrug efflux pump
APPACOFM_04797	3.53e-315	-	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Aspartate kinase
APPACOFM_04798	3.64e-179	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
APPACOFM_04799	4.78e-46	-	-	-	S	-	-	-	Winged helix-turn-helix domain (DUF2582)
APPACOFM_04800	7.28e-209	-	-	-	K	ko:K13652	-	ko00000,ko03000	methylphosphotriester-DNA alkyltransferase (AraC XylS family)
APPACOFM_04801	3.78e-85	-	-	-	S	ko:K06996	-	ko00000	Glyoxalase-like domain
APPACOFM_04802	1.13e-162	-	-	-	K	-	-	-	Helix-turn-helix domain
APPACOFM_04803	8.97e-204	-	-	-	K	-	-	-	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
APPACOFM_04804	1.82e-195	-	-	-	S	-	-	-	COG NOG27239 non supervised orthologous group
APPACOFM_04806	6.41e-237	-	-	-	L	-	-	-	Domain of unknown function (DUF1848)
APPACOFM_04807	2.69e-182	-	1.1.1.159, 1.3.1.25	-	IQ	ko:K00076,ko:K05783	ko00121,ko00362,ko00364,ko00622,ko01100,ko01120,ko01220,map00121,map00362,map00364,map00622,map01100,map01120,map01220	br01602,ko00000,ko00001,ko00002,ko01000	Oxidoreductase, short chain dehydrogenase reductase family protein
APPACOFM_04809	2.71e-114	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
APPACOFM_04810	1.28e-148	-	-	-	-	-	-	-	-
APPACOFM_04811	1.27e-88	-	-	-	-	-	-	-	-
APPACOFM_04812	2.01e-288	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
APPACOFM_04813	1.25e-72	-	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
APPACOFM_04814	0.0	accC	6.3.4.14, 6.4.1.2, 6.4.1.3	-	I	ko:K01961,ko:K01965	ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase
APPACOFM_04815	4.55e-91	-	6.4.1.1	-	I	ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Biotin-requiring enzyme
APPACOFM_04816	0.0	-	2.1.3.15, 6.4.1.3	-	I	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Carboxyl transferase domain
APPACOFM_04817	1.71e-26	-	-	-	P	-	-	-	Type I phosphodiesterase / nucleotide pyrophosphatase
APPACOFM_04818	0.0	-	-	-	P	-	-	-	Type I phosphodiesterase / nucleotide pyrophosphatase
APPACOFM_04819	5.85e-231	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_04820	2.4e-194	-	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	N-acetylmuramoyl-L-alanine amidase
APPACOFM_04821	2.61e-14	-	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	N-acetylmuramoyl-L-alanine amidase
APPACOFM_04822	0.0	metZ	2.5.1.49	-	E	ko:K01740,ko:K10764	ko00270,ko00920,ko01100,map00270,map00920,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
APPACOFM_04823	3.05e-186	-	-	-	S	-	-	-	Beta-lactamase superfamily domain
APPACOFM_04824	5.42e-91	-	-	-	S	-	-	-	Domain of unknown function (DUF4369)
APPACOFM_04825	3.9e-210	-	-	-	M	-	-	-	Putative OmpA-OmpF-like porin family
APPACOFM_04826	0.0	-	-	-	-	-	-	-	-
APPACOFM_04827	6e-24	-	-	-	-	-	-	-	-
APPACOFM_04828	6.88e-297	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
APPACOFM_04829	4.79e-103	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
APPACOFM_04830	5.65e-121	-	-	-	L	-	-	-	Arm DNA-binding domain
APPACOFM_04831	2.1e-64	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_04832	6.79e-20	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_04833	0.0	-	-	-	LV	-	-	-	COG COG1002 Type II restriction enzyme, methylase subunits
APPACOFM_04834	2.32e-171	-	-	-	L	-	-	-	Transposase domain (DUF772)
APPACOFM_04835	5.58e-59	-	-	-	L	-	-	-	Transposase, Mutator family
APPACOFM_04836	0.0	-	-	-	C	-	-	-	lyase activity
APPACOFM_04837	0.0	-	-	-	C	-	-	-	HEAT repeats
APPACOFM_04838	0.0	-	-	-	C	-	-	-	lyase activity
APPACOFM_04839	0.0	-	-	-	S	-	-	-	Psort location OuterMembrane, score
APPACOFM_04840	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF4876)
APPACOFM_04841	0.0	-	-	-	P	-	-	-	COG NOG11715 non supervised orthologous group
APPACOFM_04843	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_04844	1.56e-198	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_04846	6.45e-08	-	-	-	L	-	-	-	Helicase conserved C-terminal domain
APPACOFM_04847	2.18e-88	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_04848	2.22e-186	-	-	-	D	-	-	-	ATPase involved in chromosome partitioning K01529
APPACOFM_04849	5.66e-88	-	-	-	S	-	-	-	COG NOG29850 non supervised orthologous group
APPACOFM_04850	4.88e-96	-	-	-	S	-	-	-	COG NOG28168 non supervised orthologous group
APPACOFM_04852	2.38e-143	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_04853	1.3e-179	-	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
APPACOFM_04854	2.58e-209	btuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
APPACOFM_04855	1.01e-276	-	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
APPACOFM_04856	0.0	-	-	-	H	ko:K02014	-	ko00000,ko02000	PFAM TonB-dependent receptor, beta-barrel
APPACOFM_04857	3.4e-282	-	-	-	S	-	-	-	COG NOG25284 non supervised orthologous group
APPACOFM_04858	0.0	-	-	-	S	-	-	-	COG NOG23386 non supervised orthologous group
APPACOFM_04859	0.0	-	-	-	S	-	-	-	non supervised orthologous group
APPACOFM_04860	3.99e-232	-	-	-	S	-	-	-	COG NOG26801 non supervised orthologous group
APPACOFM_04861	2.64e-153	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
APPACOFM_04862	1.52e-32	-	-	-	L	-	-	-	DNA integration
APPACOFM_04863	1.1e-185	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
APPACOFM_04864	4.64e-170	-	-	-	K	-	-	-	transcriptional regulator
APPACOFM_04865	3.08e-146	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
APPACOFM_04866	1.5e-310	-	-	-	MU	-	-	-	Efflux transporter, outer membrane factor lipoprotein, NodT family
APPACOFM_04867	0.0	-	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
APPACOFM_04868	4.94e-253	-	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
APPACOFM_04869	5.53e-207	thiD	2.7.1.49, 2.7.4.7	-	K	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	transcriptional regulator (AraC family)
APPACOFM_04870	0.0	maeB	1.1.1.38, 1.1.1.40	-	C	ko:K00027,ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
APPACOFM_04871	4.83e-30	-	-	-	-	-	-	-	-
APPACOFM_04872	0.0	gdhA	1.4.1.4	-	C	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
APPACOFM_04873	0.0	katA	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	Belongs to the catalase family
APPACOFM_04874	0.0	ppsA	-	-	GKT	-	-	-	Pyruvate phosphate dikinase, PEP pyruvate binding domain
APPACOFM_04875	0.0	gdh	1.4.1.4	-	C	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
APPACOFM_04876	8.76e-282	pepQ	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	xaa-pro dipeptidase K01271
APPACOFM_04877	0.0	cca	2.7.7.19, 2.7.7.72	-	J	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	tRNA nucleotidyltransferase poly(A) polymerase
APPACOFM_04878	1.18e-191	-	-	-	-	-	-	-	-
APPACOFM_04879	3.8e-15	-	-	-	-	-	-	-	-
APPACOFM_04880	7.68e-91	-	-	-	S	-	-	-	COG NOG26961 non supervised orthologous group
APPACOFM_04881	7.83e-129	-	-	-	S	-	-	-	COG NOG26961 non supervised orthologous group
APPACOFM_04882	3.41e-129	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
APPACOFM_04883	1.48e-215	ddh	1.4.1.16	-	E	ko:K03340	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
APPACOFM_04884	1.29e-13	-	-	-	E	-	-	-	Domain of Unknown Function with PDB structure (DUF3857)
APPACOFM_04885	1.02e-72	-	-	-	-	-	-	-	-
APPACOFM_04886	2.07e-171	hly-III	-	-	S	ko:K11068	-	ko00000,ko02042	membrane protein, hemolysin III homolog
APPACOFM_04887	1.02e-42	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix domain
APPACOFM_04888	2.62e-100	-	-	-	-	-	-	-	-
APPACOFM_04889	7.45e-167	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	COG COG0120 Ribose 5-phosphate isomerase
APPACOFM_04890	1.75e-252	-	-	-	L	-	-	-	Protein of unknown function (DUF3987)
APPACOFM_04891	3.05e-263	-	-	-	L	-	-	-	Protein of unknown function (DUF3987)
APPACOFM_04893	3.38e-50	-	-	-	S	-	-	-	Domain of unknown function (DUF4248)
APPACOFM_04894	1.53e-266	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_04895	3.62e-100	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_04896	3.36e-109	-	3.5.1.28	-	V	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
APPACOFM_04897	3.04e-09	-	-	-	-	-	-	-	-
APPACOFM_04898	0.0	-	-	-	M	-	-	-	COG3209 Rhs family protein
APPACOFM_04899	0.0	-	-	-	M	-	-	-	COG COG3209 Rhs family protein
APPACOFM_04900	9.25e-71	-	-	-	-	-	-	-	-
APPACOFM_04902	1.41e-84	-	-	-	-	-	-	-	-
APPACOFM_04903	0.0	nrdD	1.1.98.6	-	FK	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.96
APPACOFM_04904	1.37e-119	nrdG	1.97.1.4	-	C	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
APPACOFM_04905	0.0	-	-	-	EGP	ko:K08169	-	ko00000,ko02000	the major facilitator superfamily
APPACOFM_04906	0.0	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
APPACOFM_04907	8.35e-277	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
APPACOFM_04908	4.34e-201	nlpD_1	-	-	M	-	-	-	Peptidase, M23 family
APPACOFM_04909	2.8e-124	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
APPACOFM_04910	6e-217	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
APPACOFM_04911	1.12e-149	-	-	-	S	-	-	-	COG NOG11645 non supervised orthologous group
APPACOFM_04912	6.13e-165	yeaZ	-	-	O	ko:K14742	-	ko00000,ko03016	Universal bacterial protein YeaZ
APPACOFM_04913	1.59e-185	-	-	-	S	-	-	-	stress-induced protein
APPACOFM_04914	2.84e-143	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
APPACOFM_04915	2.12e-49	-	-	-	-	-	-	-	-
APPACOFM_04916	1.42e-151	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
APPACOFM_04917	2.96e-266	-	-	-	S	ko:K07133	-	ko00000	ATPase (AAA superfamily)
APPACOFM_04918	1.62e-11	-	-	-	S	ko:K07133	-	ko00000	ATPase (AAA superfamily)
APPACOFM_04919	3.8e-251	-	-	-	S	ko:K07098	-	ko00000	Ser Thr phosphatase family protein
APPACOFM_04920	1.19e-202	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the MenA family. Type 1 subfamily
APPACOFM_04921	1.4e-287	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
APPACOFM_04922	9.94e-210	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
APPACOFM_04923	1.48e-118	-	-	-	S	ko:K07095	-	ko00000	Psort location Cytoplasmic, score 8.96
APPACOFM_04924	0.0	ppk	2.7.4.1	-	H	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
APPACOFM_04925	0.0	-	-	-	U	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_04927	8.11e-97	-	-	-	L	-	-	-	DNA-binding protein
APPACOFM_04928	8.18e-36	-	-	-	S	-	-	-	Domain of unknown function (DUF4248)
APPACOFM_04929	0.0	-	-	-	T	-	-	-	Psort location CytoplasmicMembrane, score
APPACOFM_04930	2.21e-126	-	-	-	-	-	-	-	-
APPACOFM_04931	1.44e-57	-	-	-	S	-	-	-	WYL_2, Sm-like SH3 beta-barrel fold
APPACOFM_04932	8.3e-21	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_04933	3.35e-78	-	-	-	L	-	-	-	HNH endonuclease domain protein
APPACOFM_04934	7.16e-82	-	-	-	L	-	-	-	HNH endonuclease domain protein
APPACOFM_04935	2.19e-109	-	-	-	V	-	-	-	N-acetylmuramoyl-L-alanine amidase
APPACOFM_04936	1.45e-27	-	-	-	L	-	-	-	DnaD domain protein
APPACOFM_04937	1.68e-106	-	-	-	L	-	-	-	DnaD domain protein
APPACOFM_04938	1.14e-192	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_04939	2.23e-37	-	-	-	P	-	-	-	Carboxypeptidase regulatory-like domain
APPACOFM_04940	0.0	-	-	-	P	-	-	-	TonB dependent receptor
APPACOFM_04941	8.5e-94	-	-	-	P	-	-	-	TonB dependent receptor
APPACOFM_04942	0.0	-	-	-	H	-	-	-	COG NOG26372 non supervised orthologous group
APPACOFM_04943	5.59e-90	divK	-	-	T	-	-	-	Response regulator receiver domain protein
APPACOFM_04944	0.0	-	-	-	S	ko:K06158	-	ko00000,ko03012	Psort location CytoplasmicMembrane, score
APPACOFM_04945	4.23e-135	-	-	-	S	-	-	-	Zeta toxin
APPACOFM_04946	2.8e-32	-	-	-	-	-	-	-	-
APPACOFM_04947	1.67e-68	-	-	-	S	-	-	-	COG NOG32090 non supervised orthologous group
APPACOFM_04948	1.39e-278	-	-	-	M	-	-	-	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
APPACOFM_04949	0.0	czcA	-	-	P	-	-	-	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
APPACOFM_04950	1.55e-307	czcA	-	-	P	-	-	-	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
APPACOFM_04951	3.01e-269	-	-	-	MU	-	-	-	outer membrane efflux protein
APPACOFM_04952	7.53e-201	-	-	-	-	-	-	-	-
APPACOFM_04953	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family
APPACOFM_04954	2.95e-161	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
APPACOFM_04955	3.67e-126	rpoE	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
APPACOFM_04956	3.55e-64	-	-	-	S	-	-	-	Domain of unknown function (DUF5056)
APPACOFM_04958	1.54e-302	cls	-	-	M	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the phospholipase D family. Cardiolipin synthase subfamily
APPACOFM_04959	8.15e-200	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
APPACOFM_04960	7.63e-117	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
APPACOFM_04961	1.62e-111	asnC	-	-	K	ko:K03718	-	ko00000,ko03000	transcriptional regulator, AsnC family
APPACOFM_04962	0.0	-	-	-	S	-	-	-	IgA Peptidase M64
APPACOFM_04963	3.17e-134	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_04964	4.13e-99	-	-	-	U	ko:K03559	-	ko00000,ko02000	COG NOG14448 non supervised orthologous group
APPACOFM_04965	6.99e-136	-	-	-	U	-	-	-	COG NOG14449 non supervised orthologous group
APPACOFM_04966	2.77e-104	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
APPACOFM_04967	3.94e-163	exbB	-	-	U	ko:K03561	-	ko00000,ko02000	MotA TolQ ExbB proton channel family
APPACOFM_04969	4.09e-171	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
APPACOFM_04970	1.33e-167	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_04971	1.68e-229	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
APPACOFM_04972	3.14e-156	-	-	-	U	ko:K03832	-	ko00000,ko02000	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
APPACOFM_04973	1.89e-158	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
APPACOFM_04974	6.97e-196	ispH	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
APPACOFM_04975	2.92e-231	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
APPACOFM_04976	9.96e-312	piuB	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
APPACOFM_04977	0.0	-	-	-	E	-	-	-	Domain of unknown function (DUF4374)
APPACOFM_04978	0.0	-	-	-	H	-	-	-	Psort location OuterMembrane, score
APPACOFM_04979	3.32e-204	-	-	-	IQ	-	-	-	Oxidoreductase, short chain dehydrogenase reductase family protein
APPACOFM_04980	7.47e-300	-	-	-	C	-	-	-	Oxidoreductase, FAD FMN-binding protein
APPACOFM_04981	2.23e-187	-	1.3.1.22	-	S	ko:K12343	ko00140,map00140	ko00000,ko00001,ko01000	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_04982	1.49e-26	-	-	-	-	-	-	-	-
APPACOFM_04983	6.45e-157	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
APPACOFM_04984	0.0	prpC	2.3.3.1, 2.3.3.5	-	C	ko:K01647,ko:K01659	ko00020,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
APPACOFM_04985	3.78e-292	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
APPACOFM_04986	0.0	acnA	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
APPACOFM_04987	0.0	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_04988	4.55e-253	ilvC	1.1.1.86	-	E	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	ketol-acid reductoisomerase
APPACOFM_04989	8.74e-182	-	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
APPACOFM_04990	1.87e-126	ilvN	2.2.1.6	-	E	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	COG0440 Acetolactate synthase, small (regulatory) subunit
APPACOFM_04991	0.0	ilvB	2.2.1.6	-	H	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Acetolactate synthase, large subunit
APPACOFM_04992	0.0	ilvD	4.2.1.9	-	H	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the IlvD Edd family
APPACOFM_04993	4.57e-129	slyD	5.2.1.8	-	G	ko:K03775	-	ko00000,ko01000,ko03110	Psort location Cytoplasmic, score
APPACOFM_04994	1.7e-298	-	-	-	S	-	-	-	Belongs to the UPF0597 family
APPACOFM_04995	1.41e-267	-	-	-	S	-	-	-	non supervised orthologous group
APPACOFM_04996	1.64e-193	-	-	-	S	-	-	-	COG NOG19137 non supervised orthologous group
APPACOFM_04997	1.9e-110	-	-	-	S	-	-	-	Calycin-like beta-barrel domain
APPACOFM_04998	3.3e-260	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
APPACOFM_04999	1.94e-221	dapE	-	-	E	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_05000	2.34e-100	dapE	-	-	E	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_05001	1.39e-258	-	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
APPACOFM_05002	1.16e-208	-	-	-	S	-	-	-	COG NOG34575 non supervised orthologous group
APPACOFM_05003	1.81e-78	-	-	-	-	-	-	-	-
APPACOFM_05004	2.37e-220	-	-	-	L	-	-	-	Integrase core domain
APPACOFM_05005	0.0	topB	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	COG0550 Topoisomerase IA
APPACOFM_05006	0.0	mutB	5.4.99.2	-	I	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.96
APPACOFM_05007	0.0	mutA	5.4.99.2	-	I	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	methylmalonyl-CoA mutase small subunit
APPACOFM_05008	0.0	-	-	-	P	ko:K07085	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_05009	6.68e-150	-	-	-	F	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_05010	0.0	-	-	-	H	ko:K02014	-	ko00000,ko02000	COG COG4206 Outer membrane cobalamin receptor protein
APPACOFM_05011	1.17e-272	-	-	-	S	-	-	-	COG NOG25284 non supervised orthologous group
APPACOFM_05012	3.57e-236	-	-	-	K	-	-	-	Periplasmic binding protein-like domain
APPACOFM_05013	0.0	-	-	-	S	-	-	-	Beta-L-arabinofuranosidase, GH127
APPACOFM_05014	3.05e-202	-	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
APPACOFM_05015	7.09e-213	btuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
APPACOFM_05017	1.6e-144	-	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
APPACOFM_05018	0.0	-	-	-	V	-	-	-	COG0534 Na -driven multidrug efflux pump
APPACOFM_05019	4.44e-134	-	-	-	T	-	-	-	Cyclic nucleotide-monophosphate binding domain
APPACOFM_05020	1.07e-142	yvoA	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
APPACOFM_05021	0.0	-	-	-	G	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_05022	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 92
APPACOFM_05023	2.67e-271	-	-	-	G	-	-	-	Transporter, major facilitator family protein
APPACOFM_05024	0.0	-	-	-	H	-	-	-	TonB-linked outer membrane protein, SusC RagA family
APPACOFM_05025	0.0	-	-	-	P	ko:K21572	-	ko00000,ko02000	non supervised orthologous group
APPACOFM_05026	4.15e-302	-	-	-	S	-	-	-	Domain of unknown function (DUF5126)
APPACOFM_05027	1.25e-293	-	-	-	S	-	-	-	Domain of unknown function
APPACOFM_05028	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 92
APPACOFM_05029	2e-268	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
APPACOFM_05030	0.0	-	-	-	G	-	-	-	COG COG0383 Alpha-mannosidase
APPACOFM_05031	2.05e-181	-	-	-	-	-	-	-	-
APPACOFM_05032	3.96e-126	-	-	-	K	-	-	-	-acetyltransferase
APPACOFM_05033	7.46e-15	-	-	-	-	-	-	-	-
APPACOFM_05034	1.83e-316	-	-	-	MU	-	-	-	Psort location OuterMembrane, score
APPACOFM_05035	0.0	-	-	-	V	-	-	-	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
APPACOFM_05036	5.85e-253	-	-	-	M	-	-	-	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
APPACOFM_05037	1.19e-205	-	-	-	K	-	-	-	transcriptional regulator (AraC family)
APPACOFM_05038	2.77e-315	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_05039	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
APPACOFM_05040	6.36e-249	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
APPACOFM_05041	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
APPACOFM_05042	9.87e-112	-	-	-	S	-	-	-	Domain of unknown function (DUF5035)
APPACOFM_05043	1.38e-184	-	-	-	-	-	-	-	-
APPACOFM_05044	2.71e-160	yfbT	-	-	S	-	-	-	HAD hydrolase, family IA, variant 3
APPACOFM_05045	0.0	fkp	-	-	S	-	-	-	GHMP kinase, N-terminal domain protein
APPACOFM_05047	5.22e-255	asnA	6.3.1.1	-	E	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 10.00
APPACOFM_05048	7.52e-165	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
APPACOFM_05051	8.55e-135	-	-	-	T	-	-	-	cyclic nucleotide binding
APPACOFM_05052	0.0	-	-	-	M	-	-	-	Psort location OuterMembrane, score 9.49
APPACOFM_05053	5.6e-75	-	-	-	H	ko:K06950	-	ko00000	Psort location Cytoplasmic, score 8.96
APPACOFM_05054	2e-287	-	-	-	S	-	-	-	protein conserved in bacteria
APPACOFM_05055	0.0	-	-	-	S	-	-	-	Purple acid Phosphatase, N-terminal domain
APPACOFM_05056	1.77e-177	-	-	-	L	-	-	-	Integrase core domain
APPACOFM_05057	2.41e-84	-	-	-	L	ko:K07483	-	ko00000	COG2963 Transposase and inactivated derivatives
APPACOFM_05058	9.01e-263	-	-	-	S	-	-	-	Protein of unknown function (DUF1016)
APPACOFM_05059	3.43e-147	-	-	-	S	ko:K03453	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_05060	2.46e-40	-	-	-	S	ko:K03453	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
APPACOFM_05061	1.39e-297	amiA	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	N-acetylmuramoyl-L-alanine amidase
APPACOFM_05062	1.18e-195	-	-	-	Q	ko:K02067	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1463 ABC-type transport system involved in resistance to organic solvents, periplasmic component
APPACOFM_05063	3.4e-50	-	-	-	-	-	-	-	-
APPACOFM_05064	2.63e-62	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_05065	6.28e-40	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
APPACOFM_05066	2.34e-62	-	-	-	-	-	-	-	-
APPACOFM_05067	4.33e-176	-	-	-	U	-	-	-	Relaxase mobilization nuclease domain protein
APPACOFM_05068	6.45e-100	-	-	-	-	-	-	-	-
APPACOFM_05069	1.64e-47	-	-	-	-	-	-	-	-
APPACOFM_05070	5.42e-255	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96