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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HAPAPPHC_00001	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HAPAPPHC_00002	0.0	nrd	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen
HAPAPPHC_00003	3.21e-270	malQ	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	4-alpha-glucanotransferase
HAPAPPHC_00004	0.0	malQ	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	4-alpha-glucanotransferase
HAPAPPHC_00005	2.48e-57	-	-	-	M	-	-	-	Integral membrane protein CcmA involved in cell shape determination
HAPAPPHC_00006	2.65e-81	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HAPAPPHC_00007	0.0	-	-	-	C	-	-	-	Hydrogenase
HAPAPPHC_00008	4.61e-314	-	-	-	S	-	-	-	Peptide-N-glycosidase F, N terminal
HAPAPPHC_00009	7.12e-142	-	-	-	U	ko:K05595	-	ko00000,ko02000	MarC family integral membrane protein
HAPAPPHC_00010	0.0	-	-	-	T	-	-	-	COG COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
HAPAPPHC_00011	7.16e-298	-	-	-	L	-	-	-	COG NOG11942 non supervised orthologous group
HAPAPPHC_00013	8.37e-126	-	-	-	K	-	-	-	Transcription termination antitermination factor NusG
HAPAPPHC_00014	2.22e-256	mraY2	-	-	M	-	-	-	UDP-N-acetylmuramyl pentapeptide phosphotransferase
HAPAPPHC_00015	2.41e-176	-	-	-	GM	-	-	-	COG4464 Capsular polysaccharide biosynthesis protein
HAPAPPHC_00016	7.54e-125	-	-	-	V	-	-	-	N-acetylmuramoyl-L-alanine amidase
HAPAPPHC_00017	3.19e-06	-	-	-	-	-	-	-	-
HAPAPPHC_00018	5.23e-107	-	-	-	L	-	-	-	regulation of translation
HAPAPPHC_00020	1.08e-13	-	-	-	S	-	-	-	Domain of unknown function (DUF4248)
HAPAPPHC_00023	1.03e-145	-	-	-	M	-	-	-	Glycosyl transferases group 1
HAPAPPHC_00024	3.65e-114	-	2.4.1.187	GT26	M	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Glycosyl transferase WecB/TagA/CpsF family
HAPAPPHC_00025	3.5e-104	-	-	-	M	ko:K01991	ko02026,map02026	ko00000,ko00001,ko02000	COG1596 Periplasmic protein involved in polysaccharide export
HAPAPPHC_00026	6.45e-231	-	-	-	DM	-	-	-	Chain length determinant protein
HAPAPPHC_00027	1.26e-41	-	-	-	DM	-	-	-	Chain length determinant protein
HAPAPPHC_00028	8.01e-41	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HAPAPPHC_00029	1.28e-107	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HAPAPPHC_00032	3.43e-16	-	-	-	M	-	-	-	Acyltransferase family
HAPAPPHC_00033	4.25e-68	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HAPAPPHC_00034	1.75e-107	-	-	-	-	-	-	-	-
HAPAPPHC_00035	3.83e-34	-	-	-	S	-	-	-	maltose O-acetyltransferase activity
HAPAPPHC_00036	1.57e-132	-	-	-	M	-	-	-	Glycosyl transferases group 1
HAPAPPHC_00037	4.37e-106	-	-	-	S	-	-	-	Pfam Glycosyl transferase family 2
HAPAPPHC_00038	1.67e-99	-	-	-	-	-	-	-	-
HAPAPPHC_00039	2.32e-254	-	1.1.1.22	-	C	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HAPAPPHC_00040	9.91e-138	-	-	-	M	-	-	-	Glycosyl transferases group 1
HAPAPPHC_00041	8e-80	-	-	-	S	-	-	-	Bacterial transferase hexapeptide (six repeats)
HAPAPPHC_00042	6.15e-240	gmd	4.2.1.47	-	M	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
HAPAPPHC_00043	3.86e-226	fcl	1.1.1.271	-	GM	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction
HAPAPPHC_00044	4.09e-235	-	-	-	S	ko:K06926	-	ko00000	AAA domain, putative AbiEii toxin, Type IV TA system
HAPAPPHC_00045	5.2e-117	-	-	-	S	-	-	-	RloB-like protein
HAPAPPHC_00046	3.37e-249	-	-	-	S	ko:K07011	-	ko00000	glycosyl transferase family 2
HAPAPPHC_00047	3.64e-219	waaM	2.3.1.241	-	M	ko:K02517	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Lipid A Biosynthesis
HAPAPPHC_00048	0.0	yqeV	2.8.4.5	-	J	ko:K18707	-	ko00000,ko01000,ko03016	Fe-S oxidoreductase
HAPAPPHC_00049	1.25e-267	-	-	-	CO	-	-	-	amine dehydrogenase activity
HAPAPPHC_00050	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycosyl hydrolase family 20, catalytic domain
HAPAPPHC_00051	0.0	-	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	Long-chain fatty acid--CoA ligase
HAPAPPHC_00053	0.0	-	-	-	P	-	-	-	Outer membrane protein beta-barrel family
HAPAPPHC_00054	0.0	ndh	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HAPAPPHC_00056	3.05e-199	-	-	-	K	ko:K20968	ko02025,map02025	ko00000,ko00001,ko03000	helix_turn_helix, arabinose operon control protein
HAPAPPHC_00058	1.27e-210	-	3.1.1.53	-	S	ko:K05970	-	ko00000,ko01000	Pfam:DUF303
HAPAPPHC_00059	9.99e-128	-	3.1.1.53	-	S	ko:K05970	-	ko00000,ko01000	Pfam:DUF303
HAPAPPHC_00060	6.41e-306	bfce	5.1.3.11	-	G	ko:K16213	-	ko00000,ko01000	Catalyzes the reversible epimerization of cellobiose to 4-O-beta-D-glucopyranosyl-D-mannose (Glc-Man)
HAPAPPHC_00061	0.0	yicJ_1	-	-	G	ko:K03292	-	ko00000	MFS/sugar transport protein
HAPAPPHC_00062	1.49e-295	-	2.4.1.281	-	G	ko:K16212	-	ko00000,ko01000	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
HAPAPPHC_00063	1.14e-281	-	3.2.1.78	GH26	G	ko:K01218,ko:K19355	ko00051,ko02024,map00051,map02024	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 26 family
HAPAPPHC_00064	3.31e-14	-	-	-	-	-	-	-	-
HAPAPPHC_00066	0.0	-	-	-	U	-	-	-	WD40-like Beta Propeller Repeat
HAPAPPHC_00067	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HAPAPPHC_00068	0.0	-	-	-	U	-	-	-	WD40-like Beta Propeller Repeat
HAPAPPHC_00069	5.94e-265	-	-	-	-	-	-	-	-
HAPAPPHC_00070	7.53e-137	soxS	-	-	CO	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	cell redox homeostasis
HAPAPPHC_00071	5e-275	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HAPAPPHC_00072	2.42e-237	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HAPAPPHC_00073	4.4e-288	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate synthase
HAPAPPHC_00074	7.58e-140	-	-	-	E	-	-	-	Acetyltransferase (GNAT) domain
HAPAPPHC_00075	1.87e-97	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HAPAPPHC_00076	1.67e-178	-	-	-	O	-	-	-	Peptidase, M48 family
HAPAPPHC_00077	0.0	mutS_2	-	-	L	-	-	-	ATPase domain of DNA mismatch repair MUTS family
HAPAPPHC_00078	8.48e-204	pldA	3.1.1.32, 3.1.1.4	-	M	ko:K01058	ko00564,ko00565,ko00590,ko00591,ko00592,ko01100,ko01110,map00564,map00565,map00590,map00591,map00592,map01100,map01110	ko00000,ko00001,ko01000	Phospholipase A1
HAPAPPHC_00079	0.0	-	2.1.3.15, 6.4.1.3	-	I	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Carboxyl transferase domain
HAPAPPHC_00080	1.03e-127	-	6.3.4.14, 6.4.1.2, 6.4.1.3	-	I	ko:K01961,ko:K01965	ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase C-terminal domain
HAPAPPHC_00081	1.29e-208	-	6.3.4.14, 6.4.1.2, 6.4.1.3	-	I	ko:K01961,ko:K01965	ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase C-terminal domain
HAPAPPHC_00082	3.14e-100	-	6.4.1.1	-	I	ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Biotin carboxyl carrier protein
HAPAPPHC_00083	2.49e-312	nhaD	-	-	P	-	-	-	Citrate transporter
HAPAPPHC_00084	2.06e-178	-	-	-	G	-	-	-	Psort location Cytoplasmic, score 8.96
HAPAPPHC_00085	1.18e-189	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HAPAPPHC_00086	7.08e-145	-	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
HAPAPPHC_00087	3.55e-146	-	-	-	S	-	-	-	COG NOG25304 non supervised orthologous group
HAPAPPHC_00088	6.28e-136	mug	-	-	L	-	-	-	DNA glycosylase
HAPAPPHC_00089	5.37e-52	-	-	-	-	-	-	-	-
HAPAPPHC_00090	6.13e-264	-	-	-	P	-	-	-	Pfam:SusD
HAPAPPHC_00091	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HAPAPPHC_00092	5.11e-208	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HAPAPPHC_00093	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Glycosyl hydrolase family 36 C-terminal domain
HAPAPPHC_00094	0.0	-	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the synthesis of xanthosine monophosphate by the NAD dependent oxidation of inosine monophosphate
HAPAPPHC_00095	1.19e-174	-	-	-	S	ko:K06911	-	ko00000	Belongs to the pirin family
HAPAPPHC_00096	0.0	-	-	-	S	-	-	-	Peptidase M64
HAPAPPHC_00097	1.34e-110	nimB	-	-	S	ko:K07005	-	ko00000	Pyridoxamine 5'-phosphate oxidase
HAPAPPHC_00098	1.16e-154	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	C-terminal domain of 1-Cys peroxiredoxin
HAPAPPHC_00099	0.0	-	-	-	T	-	-	-	Psort location CytoplasmicMembrane, score
HAPAPPHC_00100	2.13e-283	proV	3.6.3.32	-	E	ko:K02000	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Domain in cystathionine beta-synthase and other proteins.
HAPAPPHC_00101	3.14e-190	-	-	-	P	ko:K02001	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HAPAPPHC_00102	1.26e-215	-	-	-	E	ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Substrate binding domain of ABC-type glycine betaine transport system
HAPAPPHC_00103	5.31e-185	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HAPAPPHC_00104	5e-111	ftnA	1.16.3.2	-	P	ko:K02217	-	ko00000,ko01000	Iron-storage protein
HAPAPPHC_00105	2.58e-93	hsp20	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HAPAPPHC_00106	5.3e-150	-	-	-	F	-	-	-	Hydrolase of X-linked nucleoside diphosphate N terminal
HAPAPPHC_00107	2.93e-82	-	5.1.3.32	-	G	ko:K03534	-	ko00000,ko01000	L-rhamnose mutarotase
HAPAPPHC_00108	2.63e-284	-	-	-	G	ko:K02429	-	ko00000,ko02000	Major Facilitator Superfamily
HAPAPPHC_00111	3.01e-188	-	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	OmpA family
HAPAPPHC_00112	1.17e-147	nrfH	-	-	C	ko:K15876	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002	NapC/NirT cytochrome c family, N-terminal region
HAPAPPHC_00113	1.41e-281	nrfA	1.7.2.2	-	C	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
HAPAPPHC_00114	2.58e-38	nrfA	1.7.2.2	-	C	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
HAPAPPHC_00115	1.09e-278	ccs1	-	-	O	-	-	-	ResB-like family
HAPAPPHC_00116	0.0	-	-	-	M	-	-	-	Alginate export
HAPAPPHC_00117	8.06e-156	-	-	-	K	-	-	-	Cyclic nucleotide-monophosphate binding domain
HAPAPPHC_00118	5.25e-313	-	-	-	T	ko:K02481	-	ko00000,ko02022	COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains
HAPAPPHC_00119	0.0	covS	-	-	T	-	-	-	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HAPAPPHC_00120	1.44e-159	-	-	-	-	-	-	-	-
HAPAPPHC_00122	1.19e-88	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HAPAPPHC_00123	4.85e-130	blc	-	-	M	ko:K03098	-	ko00000,ko04147	Lipocalin-like domain
HAPAPPHC_00124	2.77e-221	-	-	-	L	-	-	-	COG NOG11942 non supervised orthologous group
HAPAPPHC_00125	1.99e-261	-	-	-	K	-	-	-	Participates in transcription elongation, termination and antitermination
HAPAPPHC_00126	4.97e-75	-	-	-	-	-	-	-	-
HAPAPPHC_00127	1.41e-286	-	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HAPAPPHC_00128	4.75e-231	-	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HAPAPPHC_00130	1.39e-40	-	-	-	M	-	-	-	glycosyl transferase group 1
HAPAPPHC_00131	8.85e-27	-	-	-	M	-	-	-	Lipopolysaccharide biosynthesis protein
HAPAPPHC_00132	2.87e-30	-	-	-	IQ	-	-	-	Phosphopantetheine attachment site
HAPAPPHC_00133	4.54e-133	-	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal
HAPAPPHC_00134	7.67e-92	-	-	-	IQ	-	-	-	Oxidoreductase, short chain dehydrogenase reductase family protein
HAPAPPHC_00135	2.73e-147	-	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal
HAPAPPHC_00136	4.07e-54	-	-	-	Q	-	-	-	FkbH domain protein
HAPAPPHC_00137	1.46e-155	-	-	-	Q	-	-	-	FkbH domain protein
HAPAPPHC_00138	1.48e-21	-	-	-	IQ	-	-	-	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HAPAPPHC_00140	2.51e-179	-	-	-	G	-	-	-	Domain of unknown function (DUF3473)
HAPAPPHC_00141	2.25e-57	-	-	-	GM	-	-	-	3-beta hydroxysteroid dehydrogenase/isomerase family
HAPAPPHC_00142	4.38e-141	-	-	-	GM	-	-	-	3-beta hydroxysteroid dehydrogenase/isomerase family
HAPAPPHC_00143	1.33e-166	wcgX	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	Glycosyl transferase family 4
HAPAPPHC_00144	0.0	cap5D	-	-	GM	-	-	-	Polysaccharide biosynthesis protein
HAPAPPHC_00147	3.21e-94	-	-	-	L	-	-	-	DNA-binding protein
HAPAPPHC_00148	6.44e-25	-	-	-	-	-	-	-	-
HAPAPPHC_00149	8.58e-91	-	-	-	S	-	-	-	Peptidase M15
HAPAPPHC_00153	9.03e-149	-	-	-	S	-	-	-	Transposase
HAPAPPHC_00154	1.17e-143	-	-	-	T	-	-	-	Cyclic nucleotide-monophosphate binding domain
HAPAPPHC_00155	0.0	-	-	-	MU	-	-	-	Outer membrane efflux protein
HAPAPPHC_00156	1.16e-222	-	-	-	M	ko:K01993	-	ko00000	Hemolysin secretion protein D
HAPAPPHC_00157	1.05e-214	-	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	membrane
HAPAPPHC_00158	6.18e-268	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HAPAPPHC_00159	0.0	-	-	-	E	-	-	-	Domain of Unknown Function (DUF1080)
HAPAPPHC_00160	1.81e-221	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
HAPAPPHC_00161	8.39e-182	yfbT	-	-	S	-	-	-	HAD hydrolase, family IA, variant 3
HAPAPPHC_00162	6.27e-27	-	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	regulation of translation
HAPAPPHC_00163	2.5e-52	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HAPAPPHC_00164	1.62e-255	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HAPAPPHC_00165	9.58e-244	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
HAPAPPHC_00166	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HAPAPPHC_00167	1.09e-165	-	-	-	M	-	-	-	N-terminal domain of galactosyltransferase
HAPAPPHC_00168	8.31e-253	-	-	-	-	-	-	-	-
HAPAPPHC_00169	0.0	-	-	-	O	-	-	-	Thioredoxin
HAPAPPHC_00171	6.86e-137	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HAPAPPHC_00173	7.96e-133	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HAPAPPHC_00174	2.37e-195	-	-	-	S	-	-	-	Domain of unknown function (DUF1732)
HAPAPPHC_00175	4.28e-164	yeaZ	-	-	O	ko:K14742	-	ko00000,ko03016	Universal bacterial protein YeaZ
HAPAPPHC_00177	1.04e-268	oadB	4.1.1.3	-	C	ko:K01572	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	Glutaconyl-CoA decarboxylase subunit beta
HAPAPPHC_00178	3.31e-76	mmdC	-	-	I	-	-	-	Biofilm PGA synthesis protein PgaD
HAPAPPHC_00179	5.21e-198	-	-	-	C	-	-	-	Oxaloacetate decarboxylase, gamma chain
HAPAPPHC_00180	0.0	-	-	-	I	-	-	-	Carboxyl transferase domain
HAPAPPHC_00181	2e-94	mce	5.1.99.1	-	E	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	methylmalonyl-CoA epimerase
HAPAPPHC_00182	0.0	-	-	-	P	-	-	-	CarboxypepD_reg-like domain
HAPAPPHC_00183	3.26e-129	-	-	-	C	-	-	-	nitroreductase
HAPAPPHC_00184	8.64e-177	-	-	-	S	-	-	-	Domain of unknown function (DUF2520)
HAPAPPHC_00185	1.2e-122	kdsC	3.1.3.45	-	S	ko:K03270	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase
HAPAPPHC_00186	3.63e-136	maf	-	-	D	ko:K06287	-	ko00000	Maf-like protein
HAPAPPHC_00188	7.31e-247	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HAPAPPHC_00189	0.0	-	4.2.1.82, 4.2.1.9	-	EG	ko:K01687,ko:K22396	ko00040,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00040,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the IlvD Edd family
HAPAPPHC_00190	1.17e-125	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
HAPAPPHC_00191	9.51e-129	-	-	-	C	-	-	-	Putative TM nitroreductase
HAPAPPHC_00192	4e-233	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HAPAPPHC_00193	3.41e-119	-	-	-	S	-	-	-	Protein of unknown function (DUF4199)
HAPAPPHC_00196	5.97e-242	yhiM	-	-	S	-	-	-	Protein of unknown function (DUF2776)
HAPAPPHC_00197	8.39e-194	coaX	2.7.1.33	-	F	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HAPAPPHC_00198	0.0	-	-	-	I	-	-	-	Psort location OuterMembrane, score
HAPAPPHC_00199	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat protein
HAPAPPHC_00200	6.4e-143	-	-	-	S	-	-	-	Lipopolysaccharide-assembly, LptC-related
HAPAPPHC_00201	5.49e-282	tlyC	-	-	S	ko:K03699	-	ko00000,ko02042	Hemolysin
HAPAPPHC_00202	0.0	ppiD	5.2.1.8	-	O	ko:K01802,ko:K03770	-	ko00000,ko01000,ko03110	peptidylprolyl isomerase
HAPAPPHC_00203	5.59e-249	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HAPAPPHC_00204	5.6e-250	-	-	-	L	-	-	-	Domain of unknown function (DUF4837)
HAPAPPHC_00205	3.22e-254	pdxA	1.1.1.262	-	C	ko:K00097	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the PdxA family
HAPAPPHC_00206	6.39e-107	aepX	2.7.7.15, 2.7.7.39, 5.4.2.9	-	IM	ko:K00968,ko:K00980,ko:K01841	ko00440,ko00564,ko01100,ko01120,ko01130,ko05231,map00440,map00564,map01100,map01120,map01130,map05231	ko00000,ko00001,ko00002,ko01000	Glycerol-3-phosphate cytidylyltransferase
HAPAPPHC_00207	3.41e-172	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Dehydrogenase
HAPAPPHC_00208	2.85e-211	-	-	-	I	-	-	-	CDP-alcohol phosphatidyltransferase
HAPAPPHC_00209	5.11e-204	-	-	-	I	-	-	-	Phosphate acyltransferases
HAPAPPHC_00210	1.3e-283	fhlA	-	-	K	-	-	-	ATPase (AAA
HAPAPPHC_00211	2.05e-121	lptE	-	-	S	-	-	-	Lipopolysaccharide-assembly
HAPAPPHC_00212	2.38e-174	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HAPAPPHC_00213	2.4e-75	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HAPAPPHC_00214	1.02e-70	-	-	-	S	-	-	-	Domain of unknown function (DUF4491)
HAPAPPHC_00215	2.31e-27	-	-	-	-	-	-	-	-
HAPAPPHC_00216	2.68e-73	-	-	-	-	-	-	-	-
HAPAPPHC_00219	6.76e-113	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HAPAPPHC_00220	4.46e-156	-	-	-	S	-	-	-	Tetratricopeptide repeat
HAPAPPHC_00221	6.06e-83	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HAPAPPHC_00222	1.98e-132	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HAPAPPHC_00223	2.45e-63	-	-	-	S	-	-	-	Protein of unknown function (DUF721)
HAPAPPHC_00224	0.0	ctp	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
HAPAPPHC_00225	1.18e-99	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	deaminase
HAPAPPHC_00226	0.0	dcp	3.4.15.5, 3.4.24.70	-	E	ko:K01284,ko:K01414	-	ko00000,ko01000,ko01002	peptidase
HAPAPPHC_00227	0.0	-	-	-	G	-	-	-	Glycogen debranching enzyme
HAPAPPHC_00228	2.16e-120	-	-	-	G	-	-	-	Glycogen debranching enzyme
HAPAPPHC_00229	2.96e-316	gmhA	2.4.1.346	GT4	M	ko:K13668	-	ko00000,ko01000,ko01003	Starch synthase catalytic domain
HAPAPPHC_00231	1.51e-273	amyA	3.2.1.1	GH57	G	ko:K07405	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 57 family
HAPAPPHC_00232	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4270)
HAPAPPHC_00233	2.04e-192	glgA	2.4.1.21	GT5	G	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	synthase
HAPAPPHC_00234	1.71e-204	panC	6.3.2.1	-	H	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HAPAPPHC_00235	1.77e-74	panD	4.1.1.11	-	H	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HAPAPPHC_00236	8.09e-298	-	-	-	V	-	-	-	COG0534 Na -driven multidrug efflux pump
HAPAPPHC_00237	2.31e-99	-	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
HAPAPPHC_00238	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	cadmium-exporting ATPase
HAPAPPHC_00239	6.05e-307	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HAPAPPHC_00240	1.79e-211	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HAPAPPHC_00243	0.0	-	-	-	S	-	-	-	Peptidase family M28
HAPAPPHC_00244	3.77e-47	-	-	-	-	-	-	-	-
HAPAPPHC_00245	4.61e-252	-	-	-	M	ko:K15727	-	ko00000,ko02000	Barrel-sandwich domain of CusB or HlyD membrane-fusion
HAPAPPHC_00246	0.0	-	-	-	P	ko:K15726	-	ko00000,ko02000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HAPAPPHC_00247	5.32e-282	czcC_2	-	-	MU	ko:K15725	-	ko00000,ko02000	Outer membrane efflux protein
HAPAPPHC_00248	2.33e-139	-	-	-	C	-	-	-	4Fe-4S dicluster domain
HAPAPPHC_00249	1.24e-215	-	-	-	CO	-	-	-	Domain of unknown function (DUF4369)
HAPAPPHC_00250	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
HAPAPPHC_00251	1.43e-124	-	-	-	S	-	-	-	Domain of unknown function (DUF3332)
HAPAPPHC_00252	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HAPAPPHC_00253	0.0	-	-	-	F	ko:K21572	-	ko00000,ko02000	SusD family
HAPAPPHC_00254	8.63e-226	-	-	-	S	ko:K06889	-	ko00000	Serine aminopeptidase, S33
HAPAPPHC_00255	0.0	-	-	-	S	ko:K06158	-	ko00000,ko03012	glycosyl transferase family 2
HAPAPPHC_00256	4.59e-281	-	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Amidohydrolase family
HAPAPPHC_00257	4.69e-282	-	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HAPAPPHC_00258	0.0	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	glucosamine-6-phosphate deaminase
HAPAPPHC_00259	3.22e-125	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70, region 4
HAPAPPHC_00260	1.3e-245	-	-	-	PT	-	-	-	Domain of unknown function (DUF4974)
HAPAPPHC_00261	8.55e-41	-	-	-	H	-	-	-	TonB dependent receptor
HAPAPPHC_00262	0.0	-	-	-	H	-	-	-	TonB dependent receptor
HAPAPPHC_00263	0.0	-	-	-	GM	ko:K21572	-	ko00000,ko02000	Pfam:SusD
HAPAPPHC_00264	0.0	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HAPAPPHC_00265	0.0	-	3.2.1.24	GH38	G	ko:K01191	ko00511,map00511	ko00000,ko00001,ko01000,ko04131	Alpha mannosidase middle domain
HAPAPPHC_00266	2.43e-214	-	-	-	S	ko:K03453	-	ko00000	Sodium bile acid symporter family
HAPAPPHC_00267	3.66e-12	-	-	-	L	ko:K07492	-	ko00000	Transposase
HAPAPPHC_00268	1.76e-189	-	-	-	V	-	-	-	site-specific DNA-methyltransferase (adenine-specific) activity
HAPAPPHC_00269	2.74e-287	-	-	-	-	-	-	-	-
HAPAPPHC_00270	0.0	-	-	-	S	ko:K06915	-	ko00000	Domain of unknown function DUF87
HAPAPPHC_00271	3.16e-30	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HAPAPPHC_00272	1.52e-55	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	3'-5' exonuclease activity
HAPAPPHC_00273	2.98e-245	-	-	-	S	-	-	-	Protein of unknown function (DUF1016)
HAPAPPHC_00274	5.25e-205	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HAPAPPHC_00275	0.0	-	-	-	D	-	-	-	Psort location Cytoplasmic, score 8.96
HAPAPPHC_00276	4.81e-127	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HAPAPPHC_00277	1.43e-272	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HAPAPPHC_00278	9.24e-119	ogt	2.1.1.63	-	H	ko:K00567,ko:K10778	-	ko00000,ko01000,ko03000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HAPAPPHC_00279	1.89e-115	ftnA	1.16.3.2	-	P	ko:K02217	-	ko00000,ko01000	Iron-storage protein
HAPAPPHC_00280	1.73e-102	-	-	-	S	-	-	-	Family of unknown function (DUF695)
HAPAPPHC_00281	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase N terminus
HAPAPPHC_00282	6.59e-296	-	5.4.2.12	-	G	ko:K15635	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	2,3-bisphosphoglycerate-independent phosphoglycerate mutase
HAPAPPHC_00283	0.0	thrA	1.1.1.3, 2.7.2.4	-	E	ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
HAPAPPHC_00284	5.12e-218	-	-	-	EG	-	-	-	membrane
HAPAPPHC_00285	3.99e-198	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HAPAPPHC_00286	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HAPAPPHC_00287	7.99e-120	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HAPAPPHC_00288	6.52e-64	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HAPAPPHC_00289	4.08e-29	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HAPAPPHC_00290	3.28e-123	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HAPAPPHC_00291	6.21e-106	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HAPAPPHC_00292	1.78e-89	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HAPAPPHC_00293	2.14e-48	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	ATP synthase
HAPAPPHC_00294	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HAPAPPHC_00295	3.02e-171	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
HAPAPPHC_00297	1.03e-264	-	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Biotin-lipoyl like
HAPAPPHC_00298	6.65e-118	-	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HAPAPPHC_00299	1.67e-29	-	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HAPAPPHC_00300	0.0	-	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HAPAPPHC_00301	7.86e-143	-	-	-	MU	-	-	-	Efflux transporter, outer membrane factor
HAPAPPHC_00302	1.4e-179	-	-	-	MU	-	-	-	Efflux transporter, outer membrane factor
HAPAPPHC_00303	0.0	-	-	-	H	-	-	-	lysine biosynthetic process via aminoadipic acid
HAPAPPHC_00304	0.0	-	-	-	P	-	-	-	TonB dependent receptor
HAPAPPHC_00305	0.0	-	-	-	F	ko:K21572	-	ko00000,ko02000	SusD family
HAPAPPHC_00306	7.16e-202	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
HAPAPPHC_00307	9.49e-35	-	-	-	KT	-	-	-	PspC domain protein
HAPAPPHC_00308	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HAPAPPHC_00309	1.37e-112	-	-	-	I	-	-	-	Protein of unknown function (DUF1460)
HAPAPPHC_00310	0.0	-	-	-	-	-	-	-	-
HAPAPPHC_00311	1.27e-158	-	-	-	K	ko:K21556	-	ko00000,ko03000	Crp Fnr family
HAPAPPHC_00312	2.21e-185	kdsA	2.5.1.55	-	M	ko:K01627	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the KdsA family
HAPAPPHC_00313	2.6e-220	miaA2	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HAPAPPHC_00314	3.46e-120	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HAPAPPHC_00315	2.84e-106	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HAPAPPHC_00316	2.02e-46	-	-	-	-	-	-	-	-
HAPAPPHC_00317	9.88e-63	-	-	-	-	-	-	-	-
HAPAPPHC_00318	1.15e-30	-	-	-	S	-	-	-	YtxH-like protein
HAPAPPHC_00319	8.85e-209	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
HAPAPPHC_00320	1.94e-109	-	3.5.1.28	-	V	ko:K01447	-	ko00000,ko01000	Ami_2
HAPAPPHC_00321	0.000116	-	-	-	-	-	-	-	-
HAPAPPHC_00322	5.53e-106	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
HAPAPPHC_00323	4.25e-31	-	-	-	S	-	-	-	Domain of unknown function (DUF4248)
HAPAPPHC_00324	0.0	-	-	-	L	-	-	-	COG NOG25561 non supervised orthologous group
HAPAPPHC_00325	1.52e-150	-	-	-	L	-	-	-	VirE N-terminal domain protein
HAPAPPHC_00326	5.21e-226	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
HAPAPPHC_00327	3.65e-249	-	-	-	K	-	-	-	Participates in transcription elongation, termination and antitermination
HAPAPPHC_00328	3.61e-74	-	-	-	-	-	-	-	-
HAPAPPHC_00331	5.45e-258	mraY2	-	-	M	-	-	-	UDP-N-acetylmuramyl pentapeptide phosphotransferase
HAPAPPHC_00332	5.45e-253	-	-	-	S	-	-	-	Polysaccharide biosynthesis protein
HAPAPPHC_00333	9.53e-07	-	-	-	S	-	-	-	EpsG family
HAPAPPHC_00334	4.73e-49	-	-	-	S	-	-	-	Glycosyltransferase like family 2
HAPAPPHC_00335	2.15e-147	ispD2	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
HAPAPPHC_00336	4.58e-38	-	-	-	GM	-	-	-	Male sterility protein
HAPAPPHC_00337	2.46e-72	-	4.2.1.46	-	GM	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Male sterility protein
HAPAPPHC_00338	2.37e-49	-	-	-	M	ko:K07271	-	ko00000,ko01000	LicD family
HAPAPPHC_00339	1.07e-21	-	-	-	M	ko:K07271	-	ko00000,ko01000	LicD family
HAPAPPHC_00340	1.83e-27	-	-	-	IQ	-	-	-	Phosphopantetheine attachment site
HAPAPPHC_00341	4.97e-71	-	-	-	IQ	-	-	-	COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase)
HAPAPPHC_00342	4.67e-154	-	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal
HAPAPPHC_00343	5.15e-60	-	5.1.99.1	-	E	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HAPAPPHC_00344	2.09e-221	-	-	-	Q	-	-	-	FkbH domain protein
HAPAPPHC_00345	1.17e-19	-	-	-	IQ	-	-	-	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HAPAPPHC_00347	6.19e-147	-	-	-	G	-	-	-	Domain of unknown function (DUF3473)
HAPAPPHC_00349	9.59e-67	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
HAPAPPHC_00350	3.83e-56	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
HAPAPPHC_00351	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Glutamine phosphoribosylpyrophosphate amidotransferase
HAPAPPHC_00352	3.99e-299	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HAPAPPHC_00353	1.84e-36	gcvT	2.1.2.10	-	E	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	The glycine cleavage system catalyzes the degradation of glycine
HAPAPPHC_00354	1.02e-113	gcvT	2.1.2.10	-	E	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	The glycine cleavage system catalyzes the degradation of glycine
HAPAPPHC_00355	8.04e-85	gcvT	2.1.2.10	-	E	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	The glycine cleavage system catalyzes the degradation of glycine
HAPAPPHC_00356	4.18e-127	-	-	-	S	-	-	-	Domain of unknown function (DUF4251)
HAPAPPHC_00357	1.03e-241	-	-	-	S	ko:K22230	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase NAD-binding domain protein
HAPAPPHC_00358	1.96e-273	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HAPAPPHC_00359	5.39e-136	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HAPAPPHC_00360	0.0	-	-	-	D	-	-	-	Psort location Cytoplasmic, score 8.96
HAPAPPHC_00361	0.0	nadE	6.3.5.1	-	H	ko:K01950	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HAPAPPHC_00362	6.03e-10	-	-	-	S	-	-	-	ParE toxin of type II toxin-antitoxin system, parDE
HAPAPPHC_00364	0.0	glnA	6.3.1.2	-	S	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	Belongs to the glutamine synthetase family
HAPAPPHC_00365	8.85e-309	dapL	2.6.1.83	-	E	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate
HAPAPPHC_00366	1.39e-189	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HAPAPPHC_00368	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Glutamine amidotransferase domain
HAPAPPHC_00369	0.0	gltD	1.4.1.13, 1.4.1.14	-	C	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
HAPAPPHC_00370	0.0	gltB	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	GXGXG motif
HAPAPPHC_00371	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF3843)
HAPAPPHC_00372	0.0	-	-	-	P	-	-	-	Carboxypeptidase regulatory-like domain
HAPAPPHC_00373	0.0	-	-	-	N	-	-	-	COG NOG06100 non supervised orthologous group
HAPAPPHC_00374	4.54e-40	-	-	-	S	-	-	-	MORN repeat variant
HAPAPPHC_00375	1.05e-97	hslR	-	-	J	ko:K04762	-	ko00000,ko03110	S4 domain protein
HAPAPPHC_00376	3.13e-134	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HAPAPPHC_00377	1.72e-130	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HAPAPPHC_00378	1.76e-189	-	-	-	S	ko:K07124	-	ko00000	KR domain
HAPAPPHC_00379	1.04e-256	namA	-	-	C	-	-	-	NADH:flavin oxidoreductase / NADH oxidase family
HAPAPPHC_00380	7.93e-60	-	-	-	E	-	-	-	COG NOG19114 non supervised orthologous group
HAPAPPHC_00381	0.0	czcA	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HAPAPPHC_00382	7.49e-237	-	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HAPAPPHC_00383	0.0	-	-	-	MU	-	-	-	outer membrane efflux protein
HAPAPPHC_00384	1.93e-139	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HAPAPPHC_00385	1.16e-213	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HAPAPPHC_00386	3.27e-118	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
HAPAPPHC_00387	1.36e-270	-	-	-	S	-	-	-	Acyltransferase family
HAPAPPHC_00388	5.57e-247	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
HAPAPPHC_00389	5.19e-169	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
HAPAPPHC_00391	4.12e-29	-	-	-	MU	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	Outer membrane efflux protein
HAPAPPHC_00392	5.15e-220	-	-	-	MU	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	Outer membrane efflux protein
HAPAPPHC_00393	6.37e-253	-	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HAPAPPHC_00394	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HAPAPPHC_00395	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HAPAPPHC_00396	3.29e-260	-	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
HAPAPPHC_00397	4.1e-250	-	-	-	C	ko:K07138	-	ko00000	Domain of unknown function (DUF362)
HAPAPPHC_00398	1.73e-142	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	riboflavin synthase subunit alpha
HAPAPPHC_00399	2.61e-207	dnaJ2	-	-	O	ko:K03686,ko:K05516	-	ko00000,ko03029,ko03036,ko03110	DnaJ molecular chaperone homology domain
HAPAPPHC_00400	4.38e-72	-	-	-	S	-	-	-	MerR HTH family regulatory protein
HAPAPPHC_00402	6.57e-314	-	-	-	V	-	-	-	Polysaccharide biosynthesis C-terminal domain
HAPAPPHC_00403	0.0	yihY	-	-	S	ko:K07058	-	ko00000	ribonuclease BN
HAPAPPHC_00404	0.0	degQ	-	-	O	-	-	-	deoxyribonuclease HsdR
HAPAPPHC_00405	3.25e-192	rpoD	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HAPAPPHC_00406	0.0	-	-	-	S	ko:K09704	-	ko00000	DUF1237
HAPAPPHC_00407	0.0	-	-	-	P	-	-	-	Domain of unknown function (DUF4976)
HAPAPPHC_00410	3.58e-140	-	-	-	I	-	-	-	Carboxylesterase family
HAPAPPHC_00411	7.86e-51	-	-	-	I	-	-	-	Carboxylesterase family
HAPAPPHC_00412	0.0	-	3.2.1.45	GH30	M	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 30 family
HAPAPPHC_00413	0.0	-	-	-	MP	ko:K07798	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HAPAPPHC_00414	2.04e-304	-	-	-	MU	-	-	-	Outer membrane efflux protein
HAPAPPHC_00415	0.0	-	-	-	P	ko:K07787,ko:K15726	ko02020,map02020	ko00000,ko00001,ko02000	AcrB/AcrD/AcrF family
HAPAPPHC_00416	2.34e-88	-	-	-	-	-	-	-	-
HAPAPPHC_00417	4.13e-314	-	-	-	S	-	-	-	Porin subfamily
HAPAPPHC_00418	0.0	-	-	-	P	-	-	-	ATP synthase F0, A subunit
HAPAPPHC_00419	1.29e-240	gldB	-	-	O	-	-	-	Psort location Cytoplasmic, score 8.96
HAPAPPHC_00420	2.05e-54	-	-	-	V	-	-	-	COG0534 Na -driven multidrug efflux pump
HAPAPPHC_00421	3.25e-226	-	-	-	V	-	-	-	COG0534 Na -driven multidrug efflux pump
HAPAPPHC_00422	3.78e-249	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HAPAPPHC_00424	1.76e-232	metF	1.5.1.20	-	C	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Methylenetetrahydrofolate reductase
HAPAPPHC_00425	6.31e-253	ilvE	2.6.1.42	-	EH	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
HAPAPPHC_00426	6.48e-103	-	-	-	S	ko:K07133	-	ko00000	ATPase (AAA
HAPAPPHC_00427	8.48e-165	-	-	-	S	ko:K07133	-	ko00000	ATPase (AAA
HAPAPPHC_00428	0.0	nifJ	1.2.7.1	-	C	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HAPAPPHC_00430	2.85e-288	-	-	-	M	-	-	-	Phosphate-selective porin O and P
HAPAPPHC_00431	3.4e-255	-	-	-	C	-	-	-	Aldo/keto reductase family
HAPAPPHC_00432	5.93e-190	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HAPAPPHC_00433	1.56e-126	cah	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
HAPAPPHC_00435	5.19e-254	-	-	-	S	-	-	-	Peptidase family M28
HAPAPPHC_00436	0.0	-	-	-	P	-	-	-	Carboxypeptidase regulatory-like domain
HAPAPPHC_00437	1.52e-264	-	-	-	S	-	-	-	Susd and RagB outer membrane lipoprotein
HAPAPPHC_00438	0.0	-	-	-	P	-	-	-	Carboxypeptidase regulatory-like domain
HAPAPPHC_00439	0.0	-	-	-	S	-	-	-	Susd and RagB outer membrane lipoprotein
HAPAPPHC_00440	2.52e-196	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HAPAPPHC_00441	1.07e-205	fabD	2.3.1.39	-	I	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	malonyl CoA-acyl carrier protein transacylase
HAPAPPHC_00442	2.33e-35	tatA	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HAPAPPHC_00443	2.31e-191	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HAPAPPHC_00444	3.21e-210	-	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	COG0010 Arginase agmatinase formimionoglutamate hydrolase arginase family
HAPAPPHC_00445	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 92
HAPAPPHC_00447	6.84e-232	iaaA	3.4.19.5	-	E	ko:K13051	-	ko00000,ko01000,ko01002	Asparaginase
HAPAPPHC_00448	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HAPAPPHC_00449	0.0	-	-	-	S	ko:K07137	-	ko00000	FAD-binding protein
HAPAPPHC_00450	1.06e-285	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
HAPAPPHC_00452	8.38e-191	-	5.2.1.8	-	M	ko:K03768	-	ko00000,ko01000,ko03110	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
HAPAPPHC_00453	0.0	-	-	-	P	ko:K07085	-	ko00000	TrkA C-terminal domain protein
HAPAPPHC_00454	3.29e-200	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HAPAPPHC_00455	3.28e-230	-	-	-	S	-	-	-	Trehalose utilisation
HAPAPPHC_00456	0.0	recQ2	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HAPAPPHC_00457	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	single-stranded-DNA-specific exonuclease RecJ
HAPAPPHC_00458	1.62e-119	rimN	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Belongs to the SUA5 family
HAPAPPHC_00459	0.0	-	-	-	M	-	-	-	sugar transferase
HAPAPPHC_00460	0.0	-	-	-	P	ko:K03281	-	ko00000	Chloride channel protein
HAPAPPHC_00461	1.35e-235	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HAPAPPHC_00462	6.46e-83	-	-	-	S	ko:K09790	-	ko00000	Protein of unknown function (DUF454)
HAPAPPHC_00463	0.0	katA	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	Belongs to the catalase family
HAPAPPHC_00466	6.02e-90	mip	5.2.1.8	-	O	ko:K01802	-	ko00000,ko01000	FKBP-type peptidyl-prolyl cis-trans isomerase
HAPAPPHC_00467	0.0	bpeF	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HAPAPPHC_00468	1.11e-244	-	-	-	M	-	-	-	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HAPAPPHC_00469	0.0	-	-	-	M	-	-	-	Outer membrane efflux protein
HAPAPPHC_00470	1.07e-104	-	-	-	S	ko:K09793	-	ko00000	Protein of unknown function (DUF456)
HAPAPPHC_00471	2.74e-210	-	-	-	CH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
HAPAPPHC_00472	0.0	maeB	1.1.1.38, 1.1.1.40	-	C	ko:K00027,ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020	ko00000,ko00001,ko00002,ko01000	Malic enzyme
HAPAPPHC_00473	9.21e-99	-	-	-	L	-	-	-	Bacterial DNA-binding protein
HAPAPPHC_00474	3.73e-277	-	-	-	T	-	-	-	Histidine kinase-like ATPases
HAPAPPHC_00475	2.1e-89	-	-	-	P	-	-	-	transport
HAPAPPHC_00476	5.18e-291	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HAPAPPHC_00477	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
HAPAPPHC_00478	8.86e-133	-	-	-	C	-	-	-	Nitroreductase family
HAPAPPHC_00479	0.0	nhaS3	-	-	P	-	-	-	Transporter, CPA2 family
HAPAPPHC_00480	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	1,4-alpha-glucan branching enzyme
HAPAPPHC_00481	2.01e-242	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HAPAPPHC_00482	2.57e-139	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA-3-methyladenine glycosylase
HAPAPPHC_00483	1.01e-224	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HAPAPPHC_00484	7.82e-204	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
HAPAPPHC_00485	0.0	hcp	1.7.99.1	-	C	ko:K05601	ko00910,map00910	ko00000,ko00001,ko01000	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O
HAPAPPHC_00486	1.34e-146	-	-	-	K	-	-	-	Cyclic nucleotide-monophosphate binding domain
HAPAPPHC_00487	7.08e-224	-	-	-	-	-	-	-	-
HAPAPPHC_00488	1.94e-24	-	-	-	-	-	-	-	-
HAPAPPHC_00489	4.91e-131	-	-	-	T	-	-	-	Cyclic nucleotide-monophosphate binding domain
HAPAPPHC_00490	8.63e-309	-	-	-	V	-	-	-	MatE
HAPAPPHC_00491	1.61e-142	-	-	-	EG	-	-	-	EamA-like transporter family
HAPAPPHC_00494	6.36e-108	-	-	-	O	-	-	-	Thioredoxin
HAPAPPHC_00495	4.99e-78	-	-	-	S	-	-	-	CGGC
HAPAPPHC_00496	7.08e-99	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
HAPAPPHC_00498	0.0	-	-	-	S	ko:K06158	-	ko00000,ko03012	glycosyl transferase family 2
HAPAPPHC_00499	0.0	-	-	-	M	-	-	-	Domain of unknown function (DUF3943)
HAPAPPHC_00500	1.4e-138	yadS	-	-	S	-	-	-	membrane
HAPAPPHC_00501	9.78e-261	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase, type I
HAPAPPHC_00502	6.68e-196	vicX	-	-	S	-	-	-	metallo-beta-lactamase
HAPAPPHC_00506	1.25e-239	-	-	-	C	-	-	-	Nitroreductase
HAPAPPHC_00507	0.0	ybaL_1	-	-	P	-	-	-	Sodium/hydrogen exchanger family
HAPAPPHC_00508	7.09e-115	-	-	-	S	-	-	-	Psort location OuterMembrane, score
HAPAPPHC_00509	0.0	-	-	-	I	-	-	-	Outer membrane protein transport protein, Ompp1 FadL TodX
HAPAPPHC_00510	2.09e-137	rpoE	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HAPAPPHC_00512	4.33e-153	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
HAPAPPHC_00513	6.64e-273	-	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	ComEC Rec2-related protein
HAPAPPHC_00514	8.32e-254	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	domain protein
HAPAPPHC_00515	2.18e-106	-	-	-	S	-	-	-	Domain of unknown function (DUF4827)
HAPAPPHC_00516	0.0	glmM	5.4.2.8	-	G	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucosamine mutase
HAPAPPHC_00517	5.65e-134	-	-	-	G	-	-	-	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
HAPAPPHC_00518	2.24e-140	-	-	-	G	-	-	-	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
HAPAPPHC_00519	0.0	-	-	-	E	-	-	-	Domain of Unknown Function (DUF1080)
HAPAPPHC_00520	1.09e-120	-	-	-	I	-	-	-	NUDIX domain
HAPAPPHC_00521	0.0	topB	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	DNA topoisomerase III
HAPAPPHC_00522	2.43e-128	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70, region 4
HAPAPPHC_00523	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF5107)
HAPAPPHC_00524	0.0	-	-	-	G	-	-	-	Domain of unknown function (DUF4091)
HAPAPPHC_00525	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	SusD family
HAPAPPHC_00526	2.9e-121	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HAPAPPHC_00527	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HAPAPPHC_00528	4.14e-232	-	-	-	PT	-	-	-	Domain of unknown function (DUF4974)
HAPAPPHC_00529	1.44e-122	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70, region 4
HAPAPPHC_00530	4.02e-144	-	-	-	L	-	-	-	DNA-binding protein
HAPAPPHC_00531	1.56e-229	-	-	-	PT	-	-	-	Domain of unknown function (DUF4974)
HAPAPPHC_00532	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HAPAPPHC_00533	0.0	-	-	-	F	ko:K21572	-	ko00000,ko02000	SusD family
HAPAPPHC_00534	0.0	-	3.1.6.1	-	P	ko:K01130	ko00140,ko00600,map00140,map00600	ko00000,ko00001,ko01000	C-terminal region of aryl-sulfatase
HAPAPPHC_00535	0.0	-	-	-	P	-	-	-	Domain of unknown function (DUF4976)
HAPAPPHC_00536	1.43e-273	-	-	-	G	-	-	-	Glycosyl hydrolase
HAPAPPHC_00537	4.35e-239	-	-	-	S	-	-	-	Metalloenzyme superfamily
HAPAPPHC_00538	4.64e-227	-	-	-	S	-	-	-	Endonuclease/Exonuclease/phosphatase family
HAPAPPHC_00539	0.0	-	4.1.1.3, 6.4.1.1	-	C	ko:K01571,ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko02000	Conserved carboxylase domain
HAPAPPHC_00540	7.99e-102	rpiB	5.3.1.6	-	G	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase
HAPAPPHC_00541	0.0	tkt	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the transketolase family
HAPAPPHC_00542	1.34e-163	-	-	-	F	-	-	-	NUDIX domain
HAPAPPHC_00543	9.3e-281	galK	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GHMP kinase family. GalK subfamily
HAPAPPHC_00544	9.45e-298	gluP	-	-	G	ko:K02429	-	ko00000,ko02000	Major Facilitator
HAPAPPHC_00545	2.71e-207	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Converts alpha-aldose to the beta-anomer
HAPAPPHC_00546	3.2e-42	-	-	-	M	-	-	-	metallophosphoesterase
HAPAPPHC_00547	0.0	-	-	-	M	-	-	-	metallophosphoesterase
HAPAPPHC_00550	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Efflux ABC transporter, permease protein
HAPAPPHC_00551	1.06e-122	-	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
HAPAPPHC_00552	4.32e-80	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HAPAPPHC_00553	0.0	-	-	-	-	-	-	-	-
HAPAPPHC_00554	7.69e-32	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HAPAPPHC_00555	2.47e-124	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HAPAPPHC_00556	0.0	-	-	-	O	-	-	-	ADP-ribosylglycohydrolase
HAPAPPHC_00557	5.79e-243	-	-	-	F	-	-	-	Inosine-uridine preferring nucleoside hydrolase
HAPAPPHC_00558	3.03e-232	glcU	-	-	G	ko:K05340	-	ko00000,ko02000	Sugar transport protein
HAPAPPHC_00559	3.02e-174	-	-	-	-	-	-	-	-
HAPAPPHC_00560	4.01e-87	-	-	-	S	-	-	-	GtrA-like protein
HAPAPPHC_00561	1.18e-222	-	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	Glycosyltransferase
HAPAPPHC_00562	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HAPAPPHC_00563	0.0	-	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase C-terminal domain
HAPAPPHC_00564	0.0	potA	3.6.3.29, 3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K02017,ko:K10112,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HAPAPPHC_00565	4.28e-182	-	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HAPAPPHC_00566	2.25e-171	ydcV	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HAPAPPHC_00567	0.0	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HAPAPPHC_00568	8.48e-145	yihX	3.1.3.10, 3.1.3.104	-	S	ko:K07025,ko:K20866,ko:K21063	ko00010,ko00740,ko01100,ko01110,ko01120,map00010,map00740,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Haloacid dehalogenase-like hydrolase
HAPAPPHC_00569	6.47e-59	yhhQ	-	-	U	ko:K09125	-	ko00000	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HAPAPPHC_00570	1.21e-138	-	-	-	S	-	-	-	Protein of unknown function (DUF2490)
HAPAPPHC_00571	2.1e-245	-	5.3.1.22	-	G	ko:K01816	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Xylose isomerase-like TIM barrel
HAPAPPHC_00572	1.71e-112	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70, region 4
HAPAPPHC_00573	8.81e-83	-	-	-	-	-	-	-	-
HAPAPPHC_00575	1.38e-167	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HAPAPPHC_00576	3.54e-157	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	bacteriocin export ABC transporter, lactococcin 972 group
HAPAPPHC_00577	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HAPAPPHC_00578	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HAPAPPHC_00579	7.73e-08	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	bacteriocin export ABC transporter, lactococcin 972 group
HAPAPPHC_00580	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Efflux ABC transporter, permease protein
HAPAPPHC_00581	1.41e-102	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HAPAPPHC_00582	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HAPAPPHC_00583	5.79e-176	-	-	-	E	ko:K03312	-	ko00000,ko02000	Sodium/glutamate symporter
HAPAPPHC_00584	2.21e-60	-	-	-	E	ko:K03312	-	ko00000,ko02000	Sodium/glutamate symporter
HAPAPPHC_00585	4.43e-220	-	-	-	K	-	-	-	AraC-like ligand binding domain
HAPAPPHC_00586	0.0	-	-	-	G	-	-	-	lipolytic protein G-D-S-L family
HAPAPPHC_00587	0.0	-	-	-	G	-	-	-	mannose-6-phosphate isomerase, class I
HAPAPPHC_00588	3.01e-235	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HAPAPPHC_00589	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 92
HAPAPPHC_00590	3.65e-239	-	-	-	G	-	-	-	Major Facilitator
HAPAPPHC_00591	0.0	-	-	-	G	-	-	-	COG COG0383 Alpha-mannosidase
HAPAPPHC_00592	0.0	-	-	-	P	-	-	-	TonB dependent receptor
HAPAPPHC_00593	0.0	-	-	-	GM	ko:K21572	-	ko00000,ko02000	SusD family
HAPAPPHC_00594	3.05e-07	-	-	-	S	ko:K07133	-	ko00000	AAA domain
HAPAPPHC_00596	1.08e-06	-	-	-	S	ko:K07133	-	ko00000	AAA domain
HAPAPPHC_00598	2.67e-271	-	-	-	GM	ko:K21572	-	ko00000,ko02000	SusD family
HAPAPPHC_00599	0.0	-	-	-	P	-	-	-	TonB dependent receptor
HAPAPPHC_00600	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 92
HAPAPPHC_00601	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 92
HAPAPPHC_00602	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 92
HAPAPPHC_00603	0.0	-	-	-	T	-	-	-	Histidine kinase
HAPAPPHC_00604	6.65e-152	-	-	-	F	-	-	-	Cytidylate kinase-like family
HAPAPPHC_00605	6.43e-36	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Glycosyl hydrolase family 3 C-terminal domain
HAPAPPHC_00606	8.2e-93	-	-	-	S	-	-	-	COG NOG32529 non supervised orthologous group
HAPAPPHC_00607	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF3440)
HAPAPPHC_00608	6.68e-125	ibrB	-	-	K	-	-	-	ParB-like nuclease domain
HAPAPPHC_00609	1.01e-180	thi4	-	-	H	ko:K03146	ko00730,ko01100,map00730,map01100	ko00000,ko00001	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
HAPAPPHC_00610	2.23e-97	-	-	-	-	-	-	-	-
HAPAPPHC_00611	3.09e-97	-	-	-	S	-	-	-	COG NOG32090 non supervised orthologous group
HAPAPPHC_00612	8.12e-265	-	-	-	M	-	-	-	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HAPAPPHC_00613	0.0	czcA	-	-	P	ko:K07787	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HAPAPPHC_00614	4.76e-269	-	-	-	MU	-	-	-	Outer membrane efflux protein
HAPAPPHC_00615	2.36e-220	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	2-nitropropane dioxygenase
HAPAPPHC_00617	0.0	-	3.4.15.5	-	E	ko:K01284	-	ko00000,ko01000,ko01002	Peptidase family M3
HAPAPPHC_00618	0.0	-	3.4.15.5	-	E	ko:K01284	-	ko00000,ko01000,ko01002	Peptidase family M3
HAPAPPHC_00619	4.46e-227	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
HAPAPPHC_00620	7.32e-270	-	-	-	K	-	-	-	Participates in transcription elongation, termination and antitermination
HAPAPPHC_00621	2.97e-95	-	-	-	-	-	-	-	-
HAPAPPHC_00622	1.03e-100	-	-	-	G	-	-	-	Psort location Cytoplasmic, score 8.96
HAPAPPHC_00623	7.79e-169	-	-	-	M	ko:K01991	ko02026,map02026	ko00000,ko00001,ko02000	Polysaccharide biosynthesis/export protein
HAPAPPHC_00624	3.44e-88	ptk_3	-	-	DM	-	-	-	Chain length determinant protein
HAPAPPHC_00625	0.0	ptk_3	-	-	DM	-	-	-	Chain length determinant protein
HAPAPPHC_00626	1.52e-262	mraY2	-	-	M	-	-	-	UDP-N-acetylmuramyl pentapeptide phosphotransferase
HAPAPPHC_00627	6.75e-110	-	3.5.1.28	-	V	ko:K01447	-	ko00000,ko01000	Ami_2
HAPAPPHC_00628	0.000452	-	-	-	-	-	-	-	-
HAPAPPHC_00630	1.98e-105	-	-	-	L	-	-	-	regulation of translation
HAPAPPHC_00631	1.44e-29	-	-	-	S	-	-	-	Domain of unknown function (DUF4248)
HAPAPPHC_00632	0.0	-	-	-	L	-	-	-	Primase C terminal 2 (PriCT-2)
HAPAPPHC_00633	3.33e-125	-	-	-	S	-	-	-	VirE N-terminal domain
HAPAPPHC_00634	1.41e-112	-	-	-	-	-	-	-	-
HAPAPPHC_00635	4.9e-290	-	-	-	S	-	-	-	Polysaccharide biosynthesis protein
HAPAPPHC_00636	1.03e-164	-	-	-	C	-	-	-	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus
HAPAPPHC_00637	1.96e-116	-	2.2.1.9	-	S	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	slime layer polysaccharide biosynthetic process
HAPAPPHC_00638	1.28e-97	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HAPAPPHC_00640	5e-61	-	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	glycosyltransferase K00754
HAPAPPHC_00642	8.4e-128	-	-	GT4	M	ko:K13004	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 1 family protein
HAPAPPHC_00643	1.42e-139	pgaA	-	-	S	-	-	-	AAA domain
HAPAPPHC_00644	1.37e-56	-	-	-	V	-	-	-	TIGR02646 family
HAPAPPHC_00645	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	amidophosphoribosyltransferase
HAPAPPHC_00646	9.32e-296	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
HAPAPPHC_00647	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase (glutamine-hydrolyzing)
HAPAPPHC_00648	1.86e-129	-	-	-	T	-	-	-	COGs COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase
HAPAPPHC_00649	3.43e-183	-	-	-	C	ko:K18928	-	ko00000	Fe-S oxidoreductase
HAPAPPHC_00650	0.0	-	-	-	C	ko:K18929	-	ko00000	4Fe-4S ferredoxin
HAPAPPHC_00651	1.26e-131	lutC	-	-	S	ko:K00782	-	ko00000	LUD domain
HAPAPPHC_00652	3.99e-279	yqhD	-	-	C	ko:K08325	ko00640,map00640	ko00000,ko00001,ko01000	alcohol dehydrogenase
HAPAPPHC_00653	2.48e-177	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HAPAPPHC_00654	2.15e-160	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
HAPAPPHC_00655	6.29e-179	trpC	4.1.1.48	-	E	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
HAPAPPHC_00656	1.51e-236	trpD	2.4.2.18, 4.1.3.27	-	E	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HAPAPPHC_00657	1.01e-135	trpG	2.6.1.85, 4.1.3.27	-	EH	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Glutamine amidotransferase class-I
HAPAPPHC_00658	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Anthranilate synthase component I, N terminal region
HAPAPPHC_00659	1.94e-287	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HAPAPPHC_00660	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Catalyzes the formation of fumarate from aspartate
HAPAPPHC_00661	2.49e-229	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
HAPAPPHC_00662	1.8e-130	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70, region 4
HAPAPPHC_00663	2.71e-181	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HAPAPPHC_00664	2.04e-86	-	-	-	S	-	-	-	Protein of unknown function, DUF488
HAPAPPHC_00665	1.51e-235	-	-	-	PT	-	-	-	Domain of unknown function (DUF4974)
HAPAPPHC_00666	0.0	-	-	-	P	-	-	-	CarboxypepD_reg-like domain
HAPAPPHC_00667	1.99e-143	-	-	-	S	-	-	-	Susd and RagB outer membrane lipoprotein
HAPAPPHC_00668	2.33e-194	-	-	-	S	-	-	-	Susd and RagB outer membrane lipoprotein
HAPAPPHC_00669	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HAPAPPHC_00670	0.0	-	-	-	S	-	-	-	Susd and RagB outer membrane lipoprotein
HAPAPPHC_00671	2.98e-90	-	-	-	K	ko:K07722	-	ko00000,ko03000	transcriptional regulator
HAPAPPHC_00672	0.0	-	-	-	P	ko:K02014	-	ko00000,ko02000	TonB dependent receptor
HAPAPPHC_00673	5.83e-87	divK	-	-	T	-	-	-	Response regulator receiver domain
HAPAPPHC_00674	0.0	eam	5.4.3.2	-	E	ko:K01843	ko00310,map00310	ko00000,ko00001,ko01000	KamA family
HAPAPPHC_00675	1.38e-120	-	-	-	S	-	-	-	Uncharacterized protein containing a ferredoxin domain (DUF2148)
HAPAPPHC_00676	1.5e-207	-	-	-	-	-	-	-	-
HAPAPPHC_00678	7.1e-292	mleN	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
HAPAPPHC_00679	0.0	-	-	-	M	-	-	-	CarboxypepD_reg-like domain
HAPAPPHC_00680	3.37e-46	-	-	-	M	-	-	-	CarboxypepD_reg-like domain
HAPAPPHC_00681	1.49e-152	-	-	-	-	-	-	-	-
HAPAPPHC_00685	0.0	-	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
HAPAPPHC_00686	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HAPAPPHC_00687	1.43e-111	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
HAPAPPHC_00688	4.32e-163	-	-	-	S	-	-	-	Outer membrane protein beta-barrel domain
HAPAPPHC_00689	1.37e-109	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
HAPAPPHC_00690	5.24e-184	-	-	-	K	ko:K13641,ko:K19333	-	ko00000,ko03000	helix_turn_helix isocitrate lyase regulation
HAPAPPHC_00691	0.0	-	-	-	C	-	-	-	cytochrome c peroxidase
HAPAPPHC_00692	3.55e-258	-	-	-	J	-	-	-	endoribonuclease L-PSP
HAPAPPHC_00693	9.63e-133	-	5.3.1.15	-	S	ko:K09988	ko00040,map00040	ko00000,ko00001,ko01000	ABC-type sugar transport system, auxiliary component
HAPAPPHC_00694	0.0	-	-	-	S	-	-	-	Sulfatase-modifying factor enzyme 1
HAPAPPHC_00695	5.58e-164	ccmC	-	-	O	-	-	-	cytochrome c-type biogenesis protein CcsB
HAPAPPHC_00696	0.0	ccmC	-	-	O	-	-	-	cytochrome c-type biogenesis protein CcsB
HAPAPPHC_00697	1.94e-70	-	-	-	-	-	-	-	-
HAPAPPHC_00698	3.07e-239	-	2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15	-	G	ko:K00863,ko:K05878	ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.96
HAPAPPHC_00699	5.67e-134	-	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	DAK2 domain protein
HAPAPPHC_00700	3.21e-210	-	2.3.1.245	-	G	ko:K08321	ko02024,map02024	ko00000,ko00001,ko01000	DeoC/LacD family aldolase
HAPAPPHC_00701	1e-215	-	-	-	S	-	-	-	COG NOG38781 non supervised orthologous group
HAPAPPHC_00702	5.05e-314	ampG	-	-	EGP	ko:K08218	ko01501,map01501	ko00000,ko00001,ko00002,ko02000	Major Facilitator Superfamily
HAPAPPHC_00703	2.59e-262	-	2.4.1.319, 2.4.1.320	-	G	ko:K18785	-	ko00000,ko01000	beta-1,4-mannooligosaccharide phosphorylase
HAPAPPHC_00704	2.36e-73	-	-	-	-	-	-	-	-
HAPAPPHC_00705	9.97e-258	-	-	-	U	ko:K03310	-	ko00000	Sodium:alanine symporter family
HAPAPPHC_00706	0.0	eptA	-	-	S	-	-	-	Domain of unknown function (DUF1705)
HAPAPPHC_00707	0.0	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
HAPAPPHC_00708	5.45e-41	-	-	-	S	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
HAPAPPHC_00709	4.01e-212	-	-	-	S	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
HAPAPPHC_00710	3.79e-307	-	-	-	T	ko:K07713	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains
HAPAPPHC_00711	8.5e-97	-	3.5.1.28	-	V	ko:K01447	-	ko00000,ko01000	Ami_2
HAPAPPHC_00712	2.02e-66	-	-	-	L	-	-	-	regulation of translation
HAPAPPHC_00714	5.42e-41	-	-	-	S	-	-	-	P-loop ATPase and inactivated derivatives
HAPAPPHC_00716	2.98e-67	-	-	-	S	-	-	-	Domain of unknown function (DUF4842)
HAPAPPHC_00717	2.53e-52	-	-	-	S	-	-	-	COG NOG06028 non supervised orthologous group
HAPAPPHC_00718	5.03e-229	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HAPAPPHC_00719	1.68e-224	-	-	-	S	ko:K01163	-	ko00000	Uncharacterised conserved protein (DUF2156)
HAPAPPHC_00720	0.0	merA	-	-	C	ko:K21739	-	ko00000	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HAPAPPHC_00721	0.0	gnd	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HAPAPPHC_00722	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HAPAPPHC_00723	5.03e-165	pgl	3.1.1.31	-	G	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	6-phosphogluconolactonase
HAPAPPHC_00724	6.65e-107	-	-	-	M	-	-	-	Nucleoside 2-deoxyribosyltransferase like
HAPAPPHC_00725	2.01e-209	rmlA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HAPAPPHC_00726	1.03e-263	fcl	1.1.1.271	-	GM	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction
HAPAPPHC_00727	3.52e-278	gmd	4.2.1.47	-	M	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
HAPAPPHC_00728	1.57e-281	-	-	-	M	-	-	-	membrane
HAPAPPHC_00729	0.0	wcaJ_2	2.7.8.6	-	M	ko:K00996,ko:K03606	ko05111,map05111	ko00000,ko00001,ko01000,ko01005	CoA-binding domain
HAPAPPHC_00730	9.52e-92	ruvX	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HAPAPPHC_00731	4.28e-131	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HAPAPPHC_00732	0.0	-	-	-	I	-	-	-	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HAPAPPHC_00733	6.09e-70	-	-	-	I	-	-	-	Biotin-requiring enzyme
HAPAPPHC_00734	1.49e-208	-	-	-	S	-	-	-	Tetratricopeptide repeat
HAPAPPHC_00735	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HAPAPPHC_00736	8.72e-140	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HAPAPPHC_00737	2.58e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
HAPAPPHC_00738	4.38e-74	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HAPAPPHC_00739	9.9e-49	-	-	-	S	-	-	-	Pfam:RRM_6
HAPAPPHC_00740	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycosyl hydrolase family 20, catalytic domain
HAPAPPHC_00741	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 92
HAPAPPHC_00742	3.23e-219	corA	-	-	P	ko:K03284	-	ko00000,ko02000	Transporter
HAPAPPHC_00744	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HAPAPPHC_00745	5.9e-314	-	3.2.1.41	CBM48,GH13	G	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko01000	Carbohydrate-binding module 48 (Isoamylase N-terminal domain)
HAPAPPHC_00746	9.76e-295	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
HAPAPPHC_00747	4.52e-106	-	-	-	J	-	-	-	Threonyl and Alanyl tRNA synthetase second additional domain
HAPAPPHC_00748	0.0	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
HAPAPPHC_00749	5.04e-33	nrfA	1.7.2.2	-	C	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
HAPAPPHC_00750	8.53e-295	nrfA	1.7.2.2	-	C	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
HAPAPPHC_00754	0.0	-	-	-	M	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
HAPAPPHC_00755	6.94e-70	-	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HAPAPPHC_00756	0.0	htpG	-	-	O	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	Molecular chaperone HSP90
HAPAPPHC_00757	0.0	-	-	-	EGP	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HAPAPPHC_00758	1.88e-249	-	-	-	V	ko:K03543	-	ko00000,ko00002,ko02000	Barrel-sandwich domain of CusB or HlyD membrane-fusion
HAPAPPHC_00759	1.06e-297	-	-	-	MU	-	-	-	Outer membrane efflux protein
HAPAPPHC_00760	6.52e-98	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HAPAPPHC_00761	2.09e-120	isiB	-	-	C	ko:K03839	-	ko00000	Low-potential electron donor to a number of redox enzymes
HAPAPPHC_00762	0.0	bfmBAB	1.2.4.4	-	C	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	dehydrogenase E1 component
HAPAPPHC_00763	2.9e-309	bfmBB	2.3.1.61	-	C	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	2-oxoacid dehydrogenases acyltransferase (catalytic domain)
HAPAPPHC_00764	8.05e-178	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
HAPAPPHC_00765	0.0	lpdA	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dihydrolipoyl dehydrogenase
HAPAPPHC_00766	1.19e-143	-	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
HAPAPPHC_00767	1.8e-50	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
HAPAPPHC_00768	4.97e-36	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HAPAPPHC_00769	1.58e-27	-	-	-	S	-	-	-	Domain of unknown function (DUF4295)
HAPAPPHC_00770	2.42e-261	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HAPAPPHC_00771	6.92e-188	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III subunit epsilon
HAPAPPHC_00772	2.58e-276	yqhD	-	-	C	ko:K08325	ko00640,map00640	ko00000,ko00001,ko01000	alcohol dehydrogenase
HAPAPPHC_00773	3.21e-126	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HAPAPPHC_00774	7.03e-124	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HAPAPPHC_00775	3.63e-218	-	-	-	S	-	-	-	Domain of unknown function (DUF4835)
HAPAPPHC_00776	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
HAPAPPHC_00778	3.28e-23	-	-	-	K	-	-	-	LytTr DNA-binding domain protein
HAPAPPHC_00779	1.88e-120	-	-	-	KT	ko:K02477	-	ko00000,ko02022	COG3279 Response regulator of the LytR AlgR family
HAPAPPHC_00780	3.75e-244	-	-	-	T	-	-	-	Histidine kinase
HAPAPPHC_00781	4.61e-270	-	-	-	MU	-	-	-	Psort location OuterMembrane, score
HAPAPPHC_00782	1.59e-20	-	-	-	MU	-	-	-	Psort location OuterMembrane, score
HAPAPPHC_00783	0.0	-	-	-	V	-	-	-	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HAPAPPHC_00784	2.64e-244	-	-	-	M	-	-	-	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HAPAPPHC_00786	3.34e-138	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
HAPAPPHC_00787	1.59e-165	trmH	2.1.1.185	-	J	ko:K03218,ko:K03437	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HAPAPPHC_00788	7.21e-81	-	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	Has endoribonuclease activity on mRNA
HAPAPPHC_00789	0.0	-	-	-	C	-	-	-	UPF0313 protein
HAPAPPHC_00790	4.64e-70	mdh	1.1.1.37	-	C	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the LDH MDH superfamily
HAPAPPHC_00791	1.7e-149	mdh	1.1.1.37	-	C	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the LDH MDH superfamily
HAPAPPHC_00792	2.34e-275	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
HAPAPPHC_00793	0.0	-	-	-	EU	-	-	-	Peptidase, S9A B C family, catalytic domain protein
HAPAPPHC_00794	1.95e-140	-	-	-	Q	-	-	-	Mycolic acid cyclopropane synthetase
HAPAPPHC_00795	6.96e-200	ispE	2.7.1.148	-	F	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HAPAPPHC_00796	5.91e-51	-	-	-	K	-	-	-	Helix-turn-helix domain
HAPAPPHC_00799	0.0	-	-	-	G	-	-	-	Major Facilitator Superfamily
HAPAPPHC_00800	0.0	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HAPAPPHC_00801	2.17e-56	-	-	-	S	-	-	-	TSCPD domain
HAPAPPHC_00802	1.62e-158	-	-	-	T	-	-	-	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HAPAPPHC_00803	0.0	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
HAPAPPHC_00804	0.0	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
HAPAPPHC_00805	1.41e-210	-	-	-	K	-	-	-	transcriptional regulator (AraC family)
HAPAPPHC_00806	4.57e-245	-	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
HAPAPPHC_00807	1.32e-06	-	-	-	Q	-	-	-	Isochorismatase family
HAPAPPHC_00808	0.0	-	-	-	P	-	-	-	Outer membrane protein beta-barrel family
HAPAPPHC_00809	3.81e-127	marC	-	-	U	ko:K05595	-	ko00000,ko02000	UPF0056 membrane protein
HAPAPPHC_00810	0.0	ybeZ_1	-	-	T	ko:K07175	-	ko00000	Phosphate starvation protein PhoH
HAPAPPHC_00811	3.27e-92	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	Antibiotic biosynthesis monooxygenase
HAPAPPHC_00812	7.11e-13	-	-	-	S	-	-	-	Domain of unknown function (DUF4925)
HAPAPPHC_00813	9.47e-241	lptG	-	-	S	ko:K11720	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Permease, YjgP YjgQ family
HAPAPPHC_00814	1.64e-285	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HAPAPPHC_00815	0.0	-	-	-	C	-	-	-	4Fe-4S binding domain
HAPAPPHC_00816	8.64e-225	-	-	-	S	-	-	-	Domain of unknown function (DUF362)
HAPAPPHC_00818	2.47e-220	lacX	-	-	G	-	-	-	Aldose 1-epimerase
HAPAPPHC_00819	7.66e-153	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems NAD-binding component
HAPAPPHC_00820	0.0	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	COG0168 Trk-type K transport systems, membrane components
HAPAPPHC_00821	7.76e-180	-	-	-	F	-	-	-	NUDIX domain
HAPAPPHC_00822	0.0	xylB_2	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	FGGY family of carbohydrate kinases, N-terminal domain
HAPAPPHC_00823	0.0	xylA	5.3.1.5	-	G	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko01000	Xylose isomerase
HAPAPPHC_00824	0.0	-	-	-	EGP	ko:K08138	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HAPAPPHC_00825	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Efflux ABC transporter, permease protein
HAPAPPHC_00826	0.0	-	2.3.1.54, 4.1.1.83	-	C	ko:K00656,ko:K18427	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
HAPAPPHC_00827	9.84e-206	-	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	4Fe-4S single cluster domain
HAPAPPHC_00828	1.12e-211	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HAPAPPHC_00829	1.3e-238	-	-	-	M	-	-	-	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HAPAPPHC_00830	0.0	-	-	-	V	-	-	-	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HAPAPPHC_00831	5.92e-301	-	-	-	MU	-	-	-	Outer membrane efflux protein
HAPAPPHC_00832	1.57e-195	cysQ	3.1.3.7	-	P	ko:K01082	ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130	ko00000,ko00001,ko01000,ko03016	Inositol monophosphatase family
HAPAPPHC_00833	0.0	-	-	-	P	-	-	-	Citrate transporter
HAPAPPHC_00834	9.87e-139	cysC	2.7.1.25	-	F	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
HAPAPPHC_00835	7.07e-220	cysD	2.7.7.4	-	H	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase) FAD synthetase
HAPAPPHC_00836	0.0	cysN	2.7.1.25, 2.7.7.4	-	P	ko:K00955,ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily
HAPAPPHC_00837	9.71e-278	-	-	-	M	-	-	-	Sulfotransferase domain
HAPAPPHC_00838	4.54e-240	-	-	-	S	-	-	-	Putative carbohydrate metabolism domain
HAPAPPHC_00839	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HAPAPPHC_00840	1.46e-123	-	-	-	-	-	-	-	-
HAPAPPHC_00841	2.58e-125	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HAPAPPHC_00842	8.35e-74	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HAPAPPHC_00843	0.0	czcA	-	-	P	ko:K15726	-	ko00000,ko02000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HAPAPPHC_00844	4.33e-208	-	-	-	M	ko:K15727	-	ko00000,ko02000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HAPAPPHC_00845	6.29e-245	-	-	-	T	-	-	-	Histidine kinase
HAPAPPHC_00846	2.91e-179	-	-	-	T	ko:K02477	-	ko00000,ko02022	LytTr DNA-binding domain
HAPAPPHC_00847	0.0	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
HAPAPPHC_00848	0.0	-	2.7.13.3	-	T	ko:K02484,ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HAPAPPHC_00849	4.62e-154	srrA	-	-	T	ko:K07657,ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HAPAPPHC_00850	3.89e-242	-	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	N-acetylmuramoyl-L-alanine amidase
HAPAPPHC_00851	2.99e-139	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Exonuclease
HAPAPPHC_00852	5.12e-96	cspG	-	-	K	-	-	-	'Cold-shock' DNA-binding domain
HAPAPPHC_00853	3.14e-188	panB	2.1.2.11	-	H	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
HAPAPPHC_00854	1.88e-238	cbiA	6.3.5.11, 6.3.5.9	-	H	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source
HAPAPPHC_00855	6.04e-85	cbiA	6.3.5.11, 6.3.5.9	-	H	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source
HAPAPPHC_00856	6.69e-149	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	uridine kinase
HAPAPPHC_00857	4.87e-163	-	-	-	M	-	-	-	Outer membrane protein beta-barrel domain
HAPAPPHC_00858	0.0	lysM	-	-	M	-	-	-	Lysin motif
HAPAPPHC_00859	0.0	-	-	-	S	-	-	-	C-terminal domain of CHU protein family
HAPAPPHC_00860	3.73e-239	mltD_2	-	-	M	-	-	-	Transglycosylase SLT domain
HAPAPPHC_00861	1.62e-230	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
HAPAPPHC_00862	0.0	gadB	4.1.1.15, 4.1.2.27	-	E	ko:K01580,ko:K01634	ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940	ko00000,ko00001,ko00002,ko01000	Belongs to the group II decarboxylase family
HAPAPPHC_00863	6.14e-279	-	-	-	P	-	-	-	Major Facilitator Superfamily
HAPAPPHC_00864	6.7e-210	-	-	-	EG	-	-	-	EamA-like transporter family
HAPAPPHC_00866	2.86e-123	paiA	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HAPAPPHC_00867	5.3e-110	-	-	-	C	ko:K02121	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	subunit E
HAPAPPHC_00868	7.04e-215	-	-	-	C	-	-	-	Protein of unknown function (DUF2764)
HAPAPPHC_00869	0.0	atpA	3.6.3.14, 3.6.3.15	-	C	ko:K02117	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
HAPAPPHC_00870	1.39e-313	ntpB	-	-	C	ko:K02118	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	the B subunit is part of the catalytic core of the ATP synthase complex
HAPAPPHC_00871	1.96e-131	-	-	-	C	ko:K02120	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	ATP synthase subunit D
HAPAPPHC_00872	0.0	-	-	-	U	ko:K02123	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	Belongs to the V-ATPase 116 kDa subunit family
HAPAPPHC_00873	1.29e-95	-	-	-	C	ko:K02124	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	ATPase, subunit K
HAPAPPHC_00874	2.11e-82	-	-	-	K	-	-	-	Penicillinase repressor
HAPAPPHC_00875	3.66e-282	-	-	-	KT	-	-	-	BlaR1 peptidase M56
HAPAPPHC_00876	1.43e-39	-	-	-	S	-	-	-	6-bladed beta-propeller
HAPAPPHC_00878	2.76e-247	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HAPAPPHC_00879	1.06e-294	corC_1	-	-	P	ko:K03699	-	ko00000,ko02042	Transporter associated domain
HAPAPPHC_00880	5.65e-170	-	-	-	S	-	-	-	COG NOG27381 non supervised orthologous group
HAPAPPHC_00881	7.99e-142	-	-	-	S	-	-	-	flavin reductase
HAPAPPHC_00882	1.45e-107	pyrI	-	-	F	ko:K00610	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002	Involved in allosteric regulation of aspartate carbamoyltransferase
HAPAPPHC_00883	2.77e-219	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HAPAPPHC_00884	0.0	-	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Belongs to the alkaline phosphatase family
HAPAPPHC_00885	2.09e-287	pepQ	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	peptidase M24
HAPAPPHC_00886	1.36e-105	-	-	-	G	-	-	-	YhcH YjgK YiaL family protein
HAPAPPHC_00887	0.0	copA	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	Copper-exporting ATPase
HAPAPPHC_00888	1.45e-31	copA	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	Copper-exporting ATPase
HAPAPPHC_00889	1.15e-39	-	-	-	P	-	-	-	mercury ion transmembrane transporter activity
HAPAPPHC_00890	2.95e-160	hly-III	-	-	S	ko:K11068	-	ko00000,ko02042	Haemolysin-III related
HAPAPPHC_00891	2.27e-315	tldD3	-	-	S	ko:K03592	-	ko00000,ko01002	Putative modulator of DNA gyrase
HAPAPPHC_00892	0.0	tldD1	-	-	S	ko:K03568	-	ko00000,ko01002	Putative modulator of DNA gyrase
HAPAPPHC_00893	0.0	atsB	-	-	C	ko:K06871	-	ko00000	oxidizes both cysteine and serine residues to C-alpha-formylglycine in sulfatase enzyme protein substrates
HAPAPPHC_00894	0.0	arnT	-	-	M	-	-	-	Dolichyl-phosphate-mannose-protein mannosyltransferase
HAPAPPHC_00895	0.0	-	-	-	P	-	-	-	Protein of unknown function (DUF4435)
HAPAPPHC_00897	0.0	gadC	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	glutamate gamma-aminobutyrate antiporter
HAPAPPHC_00898	1.13e-167	-	-	-	P	-	-	-	Ion channel
HAPAPPHC_00899	0.0	uvrA2	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HAPAPPHC_00900	7.81e-157	uvrA2	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HAPAPPHC_00901	1.07e-37	-	-	-	-	-	-	-	-
HAPAPPHC_00902	1.41e-136	yigZ	-	-	S	-	-	-	YigZ family
HAPAPPHC_00903	7.12e-275	-	-	-	P	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HAPAPPHC_00904	0.0	nhaA	-	-	P	ko:K03313	-	ko00000,ko02000	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HAPAPPHC_00905	2.32e-39	-	-	-	S	-	-	-	Transglycosylase associated protein
HAPAPPHC_00906	0.0	malL	3.2.1.1, 3.2.1.10, 5.4.99.16	GH13	G	ko:K01182,ko:K05343	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
HAPAPPHC_00907	0.0	amyS	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Alpha-amylase domain
HAPAPPHC_00908	0.0	pbpC	2.4.1.129	GT51	M	ko:K05367	ko00550,map00550	ko00000,ko00001,ko01000,ko01003,ko01011	Penicillin-Binding Protein C-terminus Family
HAPAPPHC_00909	2.77e-103	-	-	-	-	-	-	-	-
HAPAPPHC_00910	5.37e-215	-	-	-	S	-	-	-	Toxin-antitoxin system, toxin component, Fic
HAPAPPHC_00911	0.0	-	-	-	S	ko:K06894	-	ko00000	Alpha-2-Macroglobulin
HAPAPPHC_00912	1.43e-56	ykfA	-	-	S	-	-	-	Pfam:RRM_6
HAPAPPHC_00913	4.4e-217	-	-	-	KT	-	-	-	Transcriptional regulatory protein, C terminal
HAPAPPHC_00914	0.0	-	-	-	P	-	-	-	Outer membrane protein beta-barrel family
HAPAPPHC_00916	9.51e-47	-	-	-	-	-	-	-	-
HAPAPPHC_00917	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HAPAPPHC_00918	1.16e-291	nspC	4.1.1.96	-	E	ko:K13747	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	carboxynorspermidine decarboxylase
HAPAPPHC_00920	7.77e-33	-	-	-	DJ	-	-	-	Psort location Cytoplasmic, score
HAPAPPHC_00921	6.5e-219	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HAPAPPHC_00922	1.74e-168	rimO	2.8.4.4	-	J	ko:K14441	-	ko00000,ko01000,ko03009	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12
HAPAPPHC_00923	5.06e-123	rimO	2.8.4.4	-	J	ko:K14441	-	ko00000,ko01000,ko03009	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12
HAPAPPHC_00924	4.8e-61	himA	-	-	L	ko:K03530,ko:K04764	-	ko00000,ko03032,ko03036,ko03400	Belongs to the bacterial histone-like protein family
HAPAPPHC_00925	8.86e-231	-	-	-	L	-	-	-	Belongs to the bacterial histone-like protein family
HAPAPPHC_00926	1.32e-225	moxR	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
HAPAPPHC_00927	2.62e-204	-	-	-	S	-	-	-	protein (some members contain a von Willebrand factor type A (vWA) domain)
HAPAPPHC_00928	1.89e-221	-	-	-	O	-	-	-	Psort location CytoplasmicMembrane, score
HAPAPPHC_00929	9.66e-14	batA	-	-	S	ko:K07114	-	ko00000,ko02000	Von Willebrand factor type A domain
HAPAPPHC_00930	1.91e-173	batA	-	-	S	ko:K07114	-	ko00000,ko02000	Von Willebrand factor type A domain
HAPAPPHC_00931	1.24e-234	batB	-	-	S	ko:K07114	-	ko00000,ko02000	Von Willebrand factor type A domain
HAPAPPHC_00932	6.79e-126	batC	-	-	S	-	-	-	Tetratricopeptide repeat
HAPAPPHC_00933	0.0	batD	-	-	S	-	-	-	Oxygen tolerance
HAPAPPHC_00934	1.14e-181	batE	-	-	T	-	-	-	Tetratricopeptide repeat
HAPAPPHC_00935	8.39e-167	-	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
HAPAPPHC_00936	1.94e-59	-	-	-	S	-	-	-	DNA-binding protein
HAPAPPHC_00937	2.02e-268	uspA	-	-	T	-	-	-	Belongs to the universal stress protein A family
HAPAPPHC_00939	3.74e-142	-	-	-	S	-	-	-	Rhomboid family
HAPAPPHC_00940	0.0	-	-	-	E	-	-	-	COG COG2755 Lysophospholipase L1 and related esterases
HAPAPPHC_00941	0.0	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HAPAPPHC_00942	0.0	algI	-	-	M	-	-	-	alginate O-acetyltransferase
HAPAPPHC_00943	6.49e-304	ybdG_2	-	-	M	ko:K16053	-	ko00000,ko02000	Mechanosensitive ion channel
HAPAPPHC_00944	1.05e-274	ybdG_1	-	-	M	ko:K16053	-	ko00000,ko02000	Mechanosensitive ion channel
HAPAPPHC_00945	0.0	-	-	-	S	-	-	-	Insulinase (Peptidase family M16)
HAPAPPHC_00946	1.2e-109	-	-	-	S	-	-	-	Domain of unknown function (DUF4268)
HAPAPPHC_00947	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Peptidase family M1 domain
HAPAPPHC_00948	5.43e-194	hisG	2.4.2.17	-	F	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	ATP phosphoribosyltransferase
HAPAPPHC_00949	2.66e-289	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HAPAPPHC_00950	1.01e-252	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HAPAPPHC_00951	2.61e-283	hisB	3.1.3.15, 4.2.1.19	-	E	ko:K01089,ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidine biosynthesis bifunctional protein HisB
HAPAPPHC_00952	4.57e-218	cysK	2.5.1.47	-	E	ko:K01738,ko:K12339	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HAPAPPHC_00953	1.89e-282	-	-	-	MU	-	-	-	Efflux transporter, outer membrane factor
HAPAPPHC_00954	0.0	-	-	-	V	ko:K03296	-	ko00000	AcrB/AcrD/AcrF family
HAPAPPHC_00955	1.94e-266	-	-	-	V	ko:K03296	-	ko00000	AcrB/AcrD/AcrF family
HAPAPPHC_00956	5.52e-249	-	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HAPAPPHC_00957	8.48e-204	thiD	2.7.1.49, 2.7.4.7	-	K	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	helix_turn_helix, arabinose operon control protein
HAPAPPHC_00958	4.41e-242	-	-	-	U	-	-	-	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HAPAPPHC_00959	5.47e-166	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HAPAPPHC_00960	0.0	-	-	-	G	-	-	-	Domain of unknown function (DUF5127)
HAPAPPHC_00961	3.66e-223	-	-	-	K	-	-	-	Helix-turn-helix domain
HAPAPPHC_00962	1.32e-221	-	-	-	K	-	-	-	Transcriptional regulator
HAPAPPHC_00963	8.14e-265	-	-	-	S	ko:K06889	-	ko00000	COG COG1073 Hydrolases of the alpha beta superfamily
HAPAPPHC_00964	6.56e-147	-	-	-	M	-	-	-	Psort location Cytoplasmic, score 8.96
HAPAPPHC_00965	3.25e-298	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
HAPAPPHC_00966	0.0	lacZ	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
HAPAPPHC_00967	4.08e-270	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HAPAPPHC_00968	7.58e-98	-	-	-	-	-	-	-	-
HAPAPPHC_00969	6.07e-142	-	1.11.1.5	-	C	ko:K00428	-	ko00000,ko01000	cytochrome C peroxidase
HAPAPPHC_00970	0.0	poxB	1.2.5.1, 2.2.1.6	-	EH	ko:K00156,ko:K01652	ko00290,ko00620,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Thiamine pyrophosphate enzyme, central domain
HAPAPPHC_00971	1.13e-276	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HAPAPPHC_00972	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)
HAPAPPHC_00973	2.18e-269	-	-	-	K	-	-	-	Helix-turn-helix domain
HAPAPPHC_00974	0.0	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
HAPAPPHC_00975	8.7e-83	-	-	-	-	-	-	-	-
HAPAPPHC_00976	2.93e-298	-	-	-	M	ko:K03286	-	ko00000,ko02000	OmpA family
HAPAPPHC_00982	8.2e-128	-	-	-	-	-	-	-	-
HAPAPPHC_00983	5.26e-226	-	-	-	-	-	-	-	-
HAPAPPHC_00984	1.15e-113	-	-	-	-	-	-	-	-
HAPAPPHC_00986	1.05e-108	-	-	-	L	-	-	-	regulation of translation
HAPAPPHC_00987	1.85e-118	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
HAPAPPHC_00992	2.29e-52	-	-	-	S	-	-	-	zinc-ribbon domain
HAPAPPHC_00993	6.2e-129	-	-	-	S	-	-	-	response to antibiotic
HAPAPPHC_00994	1.12e-129	-	-	-	-	-	-	-	-
HAPAPPHC_00996	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
HAPAPPHC_00997	4.37e-119	glnA	6.3.1.2	-	S	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HAPAPPHC_00998	1.39e-167	-	2.1.1.130, 2.1.1.151	-	H	ko:K03394	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Precorrin-2 C20-methyltransferase
HAPAPPHC_00999	9.52e-286	-	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
HAPAPPHC_01000	1.46e-229	-	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HAPAPPHC_01001	2.84e-239	fhuC	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HAPAPPHC_01002	1.96e-225	-	-	-	K	-	-	-	transcriptional regulator (AraC family)
HAPAPPHC_01004	1.09e-248	-	-	-	L	-	-	-	Phage integrase SAM-like domain
HAPAPPHC_01005	3.47e-164	-	1.2.5.3, 1.3.99.16	-	C	ko:K03518,ko:K07302,ko:K18930	-	ko00000,ko01000	2 iron, 2 sulfur cluster binding
HAPAPPHC_01006	7.37e-84	-	1.2.5.3, 1.3.99.16	-	C	ko:K03518,ko:K07302,ko:K18930	-	ko00000,ko01000	2 iron, 2 sulfur cluster binding
HAPAPPHC_01007	3.56e-109	-	1.2.5.3, 1.3.99.16	-	C	ko:K03518,ko:K07302,ko:K18930	-	ko00000,ko01000	2 iron, 2 sulfur cluster binding
HAPAPPHC_01008	0.0	-	1.2.5.3, 1.3.99.16	-	C	ko:K03518,ko:K07302,ko:K18930	-	ko00000,ko01000	2 iron, 2 sulfur cluster binding
HAPAPPHC_01010	6.6e-59	-	-	-	-	-	-	-	-
HAPAPPHC_01011	2.41e-100	-	-	-	S	-	-	-	Protein of unknown function (DUF2975)
HAPAPPHC_01012	3.68e-34	-	-	-	K	ko:K07727	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
HAPAPPHC_01013	1.06e-66	-	-	-	S	-	-	-	Protein of unknown function (DUF1622)
HAPAPPHC_01015	1.83e-49	-	-	-	S	-	-	-	Protein of unknown function (DUF2492)
HAPAPPHC_01016	7.61e-215	-	-	-	M	-	-	-	Protein of unknown function (DUF3078)
HAPAPPHC_01017	0.0	mltF	-	-	M	ko:K18691	-	ko00000,ko01000,ko01011	Transglycosylase SLT domain
HAPAPPHC_01018	0.0	rumA	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HAPAPPHC_01019	2.58e-147	-	-	-	L	-	-	-	COG COG2801 Transposase and inactivated derivatives
HAPAPPHC_01020	7.14e-51	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
HAPAPPHC_01021	0.0	ppdK	2.7.9.1	-	G	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the PEP-utilizing enzyme family
HAPAPPHC_01022	4.71e-263	-	-	-	T	-	-	-	Psort location CytoplasmicMembrane, score 7.88
HAPAPPHC_01023	1.89e-82	-	-	-	K	-	-	-	LytTr DNA-binding domain
HAPAPPHC_01024	8.77e-158	-	-	-	T	-	-	-	Inner membrane component of T3SS, cytoplasmic domain
HAPAPPHC_01026	1.2e-121	-	-	-	T	-	-	-	FHA domain
HAPAPPHC_01027	1.29e-193	-	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	Serine/threonine phosphatases, family 2C, catalytic domain
HAPAPPHC_01028	0.0	-	2.7.11.1	-	KLT	ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
HAPAPPHC_01029	1.18e-92	-	-	-	S	-	-	-	COG0790 FOG TPR repeat, SEL1 subfamily
HAPAPPHC_01030	2.03e-121	-	-	-	S	-	-	-	COG0790 FOG TPR repeat, SEL1 subfamily
HAPAPPHC_01031	9.23e-124	-	-	-	S	-	-	-	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
HAPAPPHC_01032	0.0	-	-	-	S	-	-	-	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
HAPAPPHC_01033	1.94e-215	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Serine acetyltransferase
HAPAPPHC_01034	1.41e-88	-	1.12.1.3	-	C	ko:K17992	-	ko00000,ko01000	Ferredoxin
HAPAPPHC_01035	0.0	nuoF	1.12.1.3, 1.6.5.3	-	C	ko:K00335,ko:K18331	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region
HAPAPPHC_01036	0.0	hndD	1.12.1.3, 1.17.1.9	-	C	ko:K00123,ko:K18332	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	Iron hydrogenase small subunit
HAPAPPHC_01037	1.32e-116	hndA	1.12.1.3	-	C	ko:K18330	-	ko00000,ko01000	Thioredoxin-like [2Fe-2S] ferredoxin
HAPAPPHC_01038	3.37e-191	-	-	-	S	ko:K06872	-	ko00000	TPM domain
HAPAPPHC_01039	8.19e-134	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
HAPAPPHC_01040	0.0	ccp	1.11.1.5	-	C	ko:K00428	-	ko00000,ko01000	Psort location Periplasmic, score
HAPAPPHC_01041	2.45e-109	rlpA	-	-	M	ko:K03642	-	ko00000	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HAPAPPHC_01042	6.61e-229	-	4.1.1.35	-	M	ko:K08678	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko00002,ko01000	GDP-mannose 4,6 dehydratase
HAPAPPHC_01043	6.01e-287	czcC	-	-	MU	ko:K15725	-	ko00000,ko02000	Outer membrane efflux protein
HAPAPPHC_01044	6.08e-253	czcB	-	-	M	ko:K15727	-	ko00000,ko02000	Barrel-sandwich domain of CusB or HlyD membrane-fusion
HAPAPPHC_01045	3.04e-66	czcA_1	-	-	P	ko:K15726	-	ko00000,ko02000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HAPAPPHC_01046	0.0	czcA_1	-	-	P	ko:K15726	-	ko00000,ko02000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HAPAPPHC_01047	3.04e-162	cusR	-	-	T	ko:K07665	ko02020,map02020	ko00000,ko00001,ko00002,ko01504,ko02022	Transcriptional regulatory protein, C terminal
HAPAPPHC_01048	4.59e-270	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
HAPAPPHC_01049	0.0	pbpF	-	-	M	-	-	-	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HAPAPPHC_01050	6.16e-236	ldhA	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HAPAPPHC_01051	5.53e-205	-	-	-	S	-	-	-	Patatin-like phospholipase
HAPAPPHC_01052	6.57e-282	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HAPAPPHC_01053	9.44e-119	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HAPAPPHC_01054	1.19e-172	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HAPAPPHC_01055	4.93e-141	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Thiamine monophosphate synthase
HAPAPPHC_01056	2.39e-177	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HAPAPPHC_01057	4.32e-307	-	-	-	M	-	-	-	Surface antigen
HAPAPPHC_01058	0.0	cbiD	2.1.1.195	-	H	ko:K02188	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
HAPAPPHC_01059	0.0	cobM	2.1.1.133, 2.1.1.271	-	H	ko:K05936	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Cobalamin biosynthesis protein CbiG
HAPAPPHC_01060	9.26e-290	cbiE	2.1.1.132	-	H	ko:K00595	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Precorrin-6y C5,15-methyltransferase (Decarboxylating), CbiE subunit
HAPAPPHC_01061	0.0	cobJ	5.4.99.60, 5.4.99.61	-	H	ko:K06042	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Precorrin-3B C(17)-methyltransferase
HAPAPPHC_01062	0.0	-	-	-	S	-	-	-	PepSY domain protein
HAPAPPHC_01063	0.0	-	-	-	P	ko:K02014	-	ko00000,ko02000	TonB dependent receptor
HAPAPPHC_01064	1.72e-215	cbiK	4.99.1.3	-	H	ko:K02190	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	CbiX
HAPAPPHC_01065	0.0	aspT	-	-	S	ko:K07085	-	ko00000	Predicted Permease Membrane Region
HAPAPPHC_01066	0.0	aspD	4.1.1.12	-	E	ko:K09758	ko00250,ko00270,ko01100,ko01230,map00250,map00270,map01100,map01230	ko00000,ko00001,ko01000	Aminotransferase class I and II
HAPAPPHC_01068	0.0	acnA	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	aconitate hydratase
HAPAPPHC_01069	5.15e-307	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Isocitrate/isopropylmalate dehydrogenase
HAPAPPHC_01070	0.0	prpC	2.3.3.1, 2.3.3.5	-	C	ko:K01647,ko:K01659	ko00020,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Citrate synthase, C-terminal domain
HAPAPPHC_01071	3.04e-57	ycnE	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
HAPAPPHC_01072	1.11e-84	-	-	-	S	-	-	-	GtrA-like protein
HAPAPPHC_01073	0.0	-	-	-	E	ko:K03294	-	ko00000	C-terminus of AA_permease
HAPAPPHC_01074	2.89e-77	-	-	-	S	-	-	-	Protein of unknown function (DUF3795)
HAPAPPHC_01075	6.55e-166	-	-	-	S	-	-	-	Enoyl-(Acyl carrier protein) reductase
HAPAPPHC_01076	1.29e-280	-	-	-	S	-	-	-	Acyltransferase family
HAPAPPHC_01077	0.0	dapE	-	-	E	-	-	-	peptidase
HAPAPPHC_01078	2.85e-305	mtaD	3.5.4.28, 3.5.4.31	-	F	ko:K12960	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine
HAPAPPHC_01079	2.32e-195	xapA	2.4.2.1	-	F	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HAPAPPHC_01083	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Belongs to the ClpA ClpB family
HAPAPPHC_01084	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HAPAPPHC_01085	2.45e-288	-	-	-	S	-	-	-	Tetratricopeptide repeat protein
HAPAPPHC_01086	1.15e-122	-	-	-	T	-	-	-	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HAPAPPHC_01087	2.71e-181	-	-	-	S	-	-	-	DNA polymerase alpha chain like domain
HAPAPPHC_01088	2.87e-32	-	-	-	K	-	-	-	DRTGG domain
HAPAPPHC_01089	3.53e-12	-	-	-	K	-	-	-	DRTGG domain
HAPAPPHC_01090	0.0	-	-	-	C	-	-	-	Iron only hydrogenase large subunit, C-terminal domain
HAPAPPHC_01091	1.02e-94	-	-	-	T	-	-	-	Histidine kinase-like ATPase domain
HAPAPPHC_01092	2.64e-75	-	-	-	K	-	-	-	DRTGG domain
HAPAPPHC_01093	0.0	pepP	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	Aminopeptidase P, N-terminal domain
HAPAPPHC_01094	3.71e-168	-	-	-	-	-	-	-	-
HAPAPPHC_01095	6.74e-112	-	-	-	O	-	-	-	Thioredoxin-like
HAPAPPHC_01096	6.61e-191	cbiO	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HAPAPPHC_01098	3.62e-79	-	-	-	K	-	-	-	Transcriptional regulator
HAPAPPHC_01100	0.0	-	-	-	P	-	-	-	Psort location OuterMembrane, score 9.52
HAPAPPHC_01101	1.47e-135	-	-	-	S	-	-	-	COG NOG28134 non supervised orthologous group
HAPAPPHC_01102	2.66e-289	serB	3.1.3.3	-	ET	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01009	phosphoserine phosphatase
HAPAPPHC_01103	1.44e-66	-	-	-	S	-	-	-	Stress responsive A/B Barrel Domain
HAPAPPHC_01104	4.32e-110	-	-	-	S	-	-	-	Putative redox-active protein (C_GCAxxG_C_C)
HAPAPPHC_01105	1.95e-158	-	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
HAPAPPHC_01106	1.13e-216	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HAPAPPHC_01107	2.19e-220	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HAPAPPHC_01108	5.71e-194	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(
HAPAPPHC_01109	4.26e-96	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HAPAPPHC_01111	7.23e-239	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HAPAPPHC_01112	1.29e-184	amn	3.2.2.4	-	F	ko:K01241	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile
HAPAPPHC_01113	1.4e-109	-	-	-	V	-	-	-	Type I restriction enzyme R protein N terminus (HSDR_N)
HAPAPPHC_01116	0.0	nqrF	1.6.5.8	-	C	ko:K00351	-	ko00000,ko01000	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway
HAPAPPHC_01117	4.31e-134	nqrE	1.6.5.8	-	C	ko:K00350	-	ko00000,ko01000	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HAPAPPHC_01118	1.05e-136	nqrD	1.6.5.8	-	C	ko:K00349	-	ko00000,ko01000	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HAPAPPHC_01119	1.83e-190	nqrC	1.6.5.8	-	C	ko:K00348	-	ko00000,ko01000	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HAPAPPHC_01120	1.15e-279	nqrB	1.6.5.8	-	C	ko:K00347	-	ko00000,ko01000	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HAPAPPHC_01121	0.0	nqrA	1.6.5.8	-	C	ko:K00346	-	ko00000,ko01000	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HAPAPPHC_01122	9.85e-317	-	-	-	S	-	-	-	Domain of unknown function (DUF5103)
HAPAPPHC_01123	1.04e-222	-	-	-	C	-	-	-	4Fe-4S binding domain
HAPAPPHC_01124	0.0	guaD	3.5.4.3	-	F	ko:K01487	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Amidohydrolase family
HAPAPPHC_01125	1e-200	fieF	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HAPAPPHC_01126	1.24e-296	-	-	-	S	-	-	-	Belongs to the UPF0597 family
HAPAPPHC_01127	1.72e-82	-	-	-	T	-	-	-	Histidine kinase
HAPAPPHC_01128	0.0	-	-	-	L	-	-	-	AAA domain
HAPAPPHC_01129	8.69e-188	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HAPAPPHC_01130	2.49e-295	ydiI	3.1.2.28	-	Q	ko:K19222	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Thioesterase superfamily
HAPAPPHC_01131	1.13e-275	entC	5.4.4.2	-	HQ	ko:K02361,ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
HAPAPPHC_01132	0.0	menD	2.2.1.9	-	H	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HAPAPPHC_01133	7.22e-199	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HAPAPPHC_01134	6.23e-174	menC	-	-	M	-	-	-	Mandelate racemase muconate lactonizing enzyme
HAPAPPHC_01135	2.46e-206	menE	6.2.1.26	-	IQ	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	O-succinylbenzoic acid--CoA ligase
HAPAPPHC_01136	1.3e-303	-	-	-	E	-	-	-	Domain of Unknown Function with PDB structure (DUF3857)
HAPAPPHC_01137	8.72e-113	-	-	-	E	-	-	-	Domain of Unknown Function with PDB structure (DUF3857)
HAPAPPHC_01138	0.0	-	-	-	E	-	-	-	Domain of Unknown Function with PDB structure (DUF3858)
HAPAPPHC_01139	0.0	-	3.2.1.35	-	G	ko:K01197	ko00531,ko01100,map00531,map01100	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	beta-N-acetylglucosaminidase
HAPAPPHC_01140	2.61e-161	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HAPAPPHC_01142	2.88e-250	-	-	-	M	-	-	-	Chain length determinant protein
HAPAPPHC_01143	0.0	kpsD	-	-	M	-	-	-	Polysaccharide biosynthesis/export protein
HAPAPPHC_01144	2.72e-187	lipB	3.1.4.55	-	S	ko:K06167	ko00440,map00440	ko00000,ko00001,ko01000	Metallo-beta-lactamase superfamily
HAPAPPHC_01145	9.62e-247	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
HAPAPPHC_01146	2.07e-200	-	-	-	S	-	-	-	COG NOG24904 non supervised orthologous group
HAPAPPHC_01147	8.72e-58	-	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	regulation of translation
HAPAPPHC_01148	2.6e-150	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	uracil phosphoribosyltransferase
HAPAPPHC_01149	0.0	-	-	-	T	-	-	-	PAS domain
HAPAPPHC_01150	0.0	-	-	-	C	-	-	-	Domain of Unknown Function (DUF1080)
HAPAPPHC_01151	0.0	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HAPAPPHC_01152	0.0	nagA	-	-	S	-	-	-	hydrolase activity, acting on glycosyl bonds
HAPAPPHC_01153	0.0	-	-	-	P	-	-	-	Domain of unknown function
HAPAPPHC_01154	0.0	-	-	-	K	ko:K21572	-	ko00000,ko02000	Pfam:SusD
HAPAPPHC_01155	0.0	-	-	-	P	-	-	-	TonB dependent receptor
HAPAPPHC_01156	1.06e-242	-	-	-	PT	-	-	-	Domain of unknown function (DUF4974)
HAPAPPHC_01157	5.48e-136	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70, region 4
HAPAPPHC_01158	9.1e-299	rhlE	3.6.4.13	-	L	ko:K11927	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Belongs to the DEAD box helicase family
HAPAPPHC_01159	4.49e-231	recQ3	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	RQC
HAPAPPHC_01160	5.08e-166	recQ3	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	RQC
HAPAPPHC_01161	1.67e-293	-	-	-	S	-	-	-	Protein of unknown function (DUF4876)
HAPAPPHC_01163	7.77e-168	-	-	-	P	-	-	-	TonB-dependent receptor plug domain
HAPAPPHC_01164	0.0	-	-	-	P	-	-	-	TonB-dependent receptor plug domain
HAPAPPHC_01165	0.0	-	-	-	K	-	-	-	Transcriptional regulator
HAPAPPHC_01166	5.37e-82	-	-	-	K	-	-	-	Transcriptional regulator
HAPAPPHC_01169	0.0	-	1.3.1.1, 1.3.98.1	-	C	ko:K00226,ko:K17723	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
HAPAPPHC_01170	0.0	-	-	-	S	-	-	-	COG NOG25960 non supervised orthologous group
HAPAPPHC_01171	1.03e-05	-	-	-	-	-	-	-	-
HAPAPPHC_01172	4.74e-151	-	4.1.3.38	-	EH	ko:K02619	ko00790,map00790	ko00000,ko00001,ko01000	Amino-transferase class IV
HAPAPPHC_01173	1.12e-244	pabB	2.6.1.85	-	EH	ko:K01665	ko00790,map00790	ko00000,ko00001,ko01000	component I
HAPAPPHC_01174	2.37e-217	pabB	3.5.1.53	-	S	ko:K12251	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	Hydrolase, carbon-nitrogen family
HAPAPPHC_01175	1.5e-257	aguA	3.5.3.12	-	E	ko:K10536	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the agmatine deiminase family
HAPAPPHC_01176	3.29e-313	-	-	-	V	-	-	-	Multidrug transporter MatE
HAPAPPHC_01177	1.62e-106	msrC	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain
HAPAPPHC_01178	0.0	-	-	-	L	-	-	-	PD-(D/E)XK nuclease superfamily
HAPAPPHC_01179	2.84e-240	gpr	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo/keto reductase family
HAPAPPHC_01180	0.0	-	-	-	P	-	-	-	Sulfatase
HAPAPPHC_01181	4.14e-93	-	-	-	S	-	-	-	Domain of unknown function (DUF4293)
HAPAPPHC_01182	5.01e-69	rpoZ	-	-	S	-	-	-	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HAPAPPHC_01183	6.61e-188	yfiO	-	-	S	ko:K05807	-	ko00000,ko02000	outer membrane assembly lipoprotein YfiO
HAPAPPHC_01184	3.4e-93	-	-	-	S	-	-	-	ACT domain protein
HAPAPPHC_01185	0.0	-	6.2.1.30	-	H	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	ko00000,ko00001,ko01000	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
HAPAPPHC_01186	1.2e-199	-	-	-	G	-	-	-	Domain of Unknown Function (DUF1080)
HAPAPPHC_01187	3.83e-155	pgmB	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HAPAPPHC_01188	9.61e-110	-	-	-	M	-	-	-	Outer membrane protein beta-barrel domain
HAPAPPHC_01189	0.0	-	-	-	M	-	-	-	Dipeptidase
HAPAPPHC_01190	0.0	-	-	-	P	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HAPAPPHC_01191	9.22e-210	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HAPAPPHC_01192	4.59e-123	-	-	-	Q	-	-	-	Thioesterase superfamily
HAPAPPHC_01193	1.5e-128	-	4.1.1.19	-	S	ko:K02626	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	arginine decarboxylase
HAPAPPHC_01194	2.29e-142	sodB	1.15.1.1	-	C	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HAPAPPHC_01197	3.05e-184	-	-	-	S	-	-	-	NigD-like N-terminal OB domain
HAPAPPHC_01199	0.0	xyl3A_3	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Glycosyl hydrolase family 3
HAPAPPHC_01200	2.88e-257	-	-	-	-	-	-	-	-
HAPAPPHC_01201	6.97e-49	-	-	-	S	-	-	-	Pfam:RRM_6
HAPAPPHC_01202	1.1e-163	-	-	-	JM	-	-	-	Nucleotidyl transferase
HAPAPPHC_01203	5.8e-216	-	-	-	HJ	-	-	-	Psort location Cytoplasmic, score 8.96
HAPAPPHC_01204	1.54e-218	-	-	-	I	-	-	-	CDP-alcohol phosphatidyltransferase
HAPAPPHC_01205	7.46e-175	-	3.1.3.102, 3.1.3.104	-	S	ko:K07025,ko:K20862	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Haloacid dehalogenase-like hydrolase
HAPAPPHC_01206	9.92e-203	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HAPAPPHC_01207	2.45e-136	-	-	-	S	-	-	-	COG NOG27188 non supervised orthologous group
HAPAPPHC_01208	4e-147	-	-	-	M	-	-	-	Outer membrane protein beta-barrel domain
HAPAPPHC_01209	5.79e-134	-	-	-	S	-	-	-	Domain of unknown function (DUF4136)
HAPAPPHC_01210	5.48e-261	-	-	-	S	-	-	-	Endonuclease/Exonuclease/phosphatase family
HAPAPPHC_01211	4.16e-115	-	-	-	M	-	-	-	Belongs to the ompA family
HAPAPPHC_01212	4.18e-71	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HAPAPPHC_01213	1.15e-90	-	-	-	T	-	-	-	Histidine kinase-like ATPases
HAPAPPHC_01214	0.0	clpB	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HAPAPPHC_01216	1.29e-182	yaaA	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
HAPAPPHC_01218	0.0	-	-	-	M	ko:K08676	-	ko00000,ko01000,ko01002	Tricorn protease homolog
HAPAPPHC_01219	1.47e-288	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HAPAPPHC_01220	0.0	-	-	-	P	-	-	-	Psort location OuterMembrane, score
HAPAPPHC_01221	6.52e-248	-	-	-	S	-	-	-	Protein of unknown function (DUF4621)
HAPAPPHC_01222	2.49e-180	-	-	-	-	-	-	-	-
HAPAPPHC_01223	2.19e-164	-	-	-	K	-	-	-	transcriptional regulatory protein
HAPAPPHC_01224	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HAPAPPHC_01225	1.5e-171	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
HAPAPPHC_01226	6.14e-233	ltd	-	-	GM	-	-	-	NAD dependent epimerase dehydratase family
HAPAPPHC_01227	1.76e-157	kbl	2.3.1.29	-	H	ko:K00639	ko00260,map00260	ko00000,ko00001,ko01000,ko01007	Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA
HAPAPPHC_01228	9.2e-98	kbl	2.3.1.29	-	H	ko:K00639	ko00260,map00260	ko00000,ko00001,ko01000,ko01007	Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA
HAPAPPHC_01229	5.33e-162	-	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidinol phosphatase
HAPAPPHC_01230	3.79e-27	-	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidinol phosphatase
HAPAPPHC_01231	5.82e-136	-	-	-	S	-	-	-	ATP cob(I)alamin adenosyltransferase
HAPAPPHC_01232	3.7e-245	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HAPAPPHC_01233	3.51e-114	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HAPAPPHC_01234	0.0	-	-	-	M	-	-	-	PDZ DHR GLGF domain protein
HAPAPPHC_01235	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HAPAPPHC_01236	3.39e-253	corA	-	-	P	ko:K03284	-	ko00000,ko02000	Mediates influx of magnesium ions
HAPAPPHC_01237	2.96e-138	-	-	-	L	-	-	-	Resolvase, N terminal domain
HAPAPPHC_01238	4.83e-264	-	-	-	S	-	-	-	Winged helix DNA-binding domain
HAPAPPHC_01239	3.44e-67	-	-	-	S	-	-	-	Putative zinc ribbon domain
HAPAPPHC_01240	1.77e-142	-	-	-	K	-	-	-	Integron-associated effector binding protein
HAPAPPHC_01241	8.47e-127	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Cupin 2, conserved barrel domain protein
HAPAPPHC_01243	7.37e-293	-	2.7.1.1	-	G	ko:K00844	ko00010,ko00051,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04910,ko04930,ko04973,ko05230,map00010,map00051,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200,map04066,map04910,map04930,map04973,map05230	ko00000,ko00001,ko00002,ko01000,ko04131	Hexokinase
HAPAPPHC_01245	1.74e-294	-	-	-	EK	ko:K00375,ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000,ko03000	Alanine-glyoxylate amino-transferase
HAPAPPHC_01246	0.0	-	-	-	K	-	-	-	helix_turn_helix gluconate operon transcriptional repressor
HAPAPPHC_01252	5.87e-229	-	-	-	-	-	-	-	-
HAPAPPHC_01253	4.04e-129	-	-	-	-	-	-	-	-
HAPAPPHC_01254	7.4e-62	-	-	-	S	-	-	-	Helix-turn-helix domain
HAPAPPHC_01255	5.59e-78	-	-	-	-	-	-	-	-
HAPAPPHC_01256	5.08e-33	-	-	-	-	-	-	-	-
HAPAPPHC_01257	7.02e-40	-	-	-	-	ko:K16905	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	-
HAPAPPHC_01258	4.06e-38	-	-	-	CP	ko:K16906	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transmembrane transport
HAPAPPHC_01259	6.24e-123	-	-	-	V	ko:K16907	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC-type multidrug transport system ATPase component
HAPAPPHC_01260	2.51e-44	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HAPAPPHC_01261	2.92e-76	-	-	-	K	-	-	-	Helix-turn-helix domain
HAPAPPHC_01262	2.02e-62	-	-	-	S	-	-	-	Domain of unknown function, B. Theta Gene description (DUF3876)
HAPAPPHC_01263	7.04e-63	-	-	-	S	-	-	-	Helix-turn-helix domain
HAPAPPHC_01265	9.26e-289	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HAPAPPHC_01267	0.0	-	-	-	S	ko:K15738	-	ko00000,ko02000	ATP-binding cassette protein, ChvD family
HAPAPPHC_01268	2.84e-163	-	-	-	C	-	-	-	Domain of Unknown Function (DUF1080)
HAPAPPHC_01269	1.09e-313	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HAPAPPHC_01270	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycosyl hydrolase family 20, catalytic domain
HAPAPPHC_01271	1.74e-210	ramA_2	-	-	S	-	-	-	Carbon-nitrogen hydrolase
HAPAPPHC_01272	2.24e-136	ramA_2	-	-	S	-	-	-	Carbon-nitrogen hydrolase
HAPAPPHC_01273	1.53e-311	-	-	-	G	-	-	-	Alpha-L-arabinofuranosidase C-terminal domain
HAPAPPHC_01274	1.55e-274	-	-	-	G	-	-	-	Alpha-L-arabinofuranosidase C-terminal domain
HAPAPPHC_01275	1.95e-78	-	-	-	T	-	-	-	cheY-homologous receiver domain
HAPAPPHC_01276	2.59e-276	-	-	-	M	-	-	-	Bacterial sugar transferase
HAPAPPHC_01277	3.01e-158	-	-	-	MU	-	-	-	Outer membrane efflux protein
HAPAPPHC_01278	0.0	-	-	-	M	-	-	-	COG NOG36677 non supervised orthologous group
HAPAPPHC_01279	9.59e-252	-	-	-	M	-	-	-	O-antigen ligase like membrane protein
HAPAPPHC_01280	4.83e-231	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score
HAPAPPHC_01281	2.61e-221	-	-	-	M	-	-	-	Psort location Cytoplasmic, score
HAPAPPHC_01282	1.57e-119	-	-	-	S	-	-	-	Hexapeptide repeat of succinyl-transferase
HAPAPPHC_01283	6.99e-137	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HAPAPPHC_01284	1.01e-61	-	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HAPAPPHC_01286	5.1e-119	-	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HAPAPPHC_01287	5.9e-202	-	-	-	M	-	-	-	Psort location Cytoplasmic, score 8.96
HAPAPPHC_01289	7.56e-96	-	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	DnaB-like helicase N terminal domain
HAPAPPHC_01290	8.97e-225	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HAPAPPHC_01293	1.87e-97	-	-	-	L	-	-	-	Bacterial DNA-binding protein
HAPAPPHC_01295	9.07e-107	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HAPAPPHC_01297	3.74e-266	-	-	-	M	-	-	-	Glycosyl transferase family group 2
HAPAPPHC_01298	9.25e-118	-	-	-	S	ko:K07011	-	ko00000	Glycosyl transferase family 2
HAPAPPHC_01299	9.28e-104	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HAPAPPHC_01300	6.15e-22	-	-	-	M	-	-	-	Glycosyl transferase family 21
HAPAPPHC_01301	2.87e-229	-	-	-	M	-	-	-	Glycosyl transferase family 21
HAPAPPHC_01302	3.45e-164	-	2.7.13.3	-	T	ko:K11527	-	ko00000,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
HAPAPPHC_01303	5.22e-82	-	2.7.13.3	-	T	ko:K11527	-	ko00000,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
HAPAPPHC_01304	4.11e-77	queD	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	6-pyruvoyl tetrahydropterin synthase
HAPAPPHC_01305	3.28e-133	queE	4.3.99.3	-	H	ko:K10026	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HAPAPPHC_01306	0.0	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides
HAPAPPHC_01307	7.48e-184	dpm1	2.4.1.83	GT2	S	ko:K00721	ko00510,ko01100,map00510,map01100	ko00000,ko00001,ko01000,ko01003	Dolichyl-phosphate beta-D-mannosyltransferase
HAPAPPHC_01308	2.28e-219	oxyR	-	-	K	ko:K04761	ko02026,map02026	ko00000,ko00001,ko03000	Transcriptional regulator
HAPAPPHC_01309	1.71e-303	-	-	-	S	-	-	-	CarboxypepD_reg-like domain
HAPAPPHC_01310	9.01e-121	-	-	-	K	ko:K03088	-	ko00000,ko03021	RNA polymerase sigma-70 factor, Bacteroides expansion family 1
HAPAPPHC_01311	2.41e-197	-	-	-	PT	-	-	-	FecR protein
HAPAPPHC_01312	0.0	-	-	-	S	-	-	-	CarboxypepD_reg-like domain
HAPAPPHC_01313	9.75e-314	-	1.1.1.136	-	M	ko:K02474,ko:K13015	ko00520,map00520	ko00000,ko00001,ko01000,ko01005	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HAPAPPHC_01314	2.66e-307	-	-	-	MU	-	-	-	Outer membrane efflux protein
HAPAPPHC_01315	0.0	-	-	-	V	-	-	-	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HAPAPPHC_01316	2.04e-230	-	-	-	M	-	-	-	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HAPAPPHC_01317	1.15e-238	nucA_1	-	-	F	ko:K01173	ko04210,map04210	ko00000,ko00001,ko03029	DNA/RNA non-specific endonuclease
HAPAPPHC_01318	7.9e-77	-	-	-	S	-	-	-	RloB-like protein
HAPAPPHC_01319	2.61e-226	-	-	-	S	ko:K06926	-	ko00000	AAA ATPase domain
HAPAPPHC_01320	1.22e-57	-	-	-	L	-	-	-	Domain of unknown function (DUF1848)
HAPAPPHC_01322	0.0	-	-	-	L	-	-	-	ATP-dependent DNA helicase RecQ
HAPAPPHC_01323	3.44e-182	-	-	-	L	-	-	-	Domain of unknown function (DUF1848)
HAPAPPHC_01325	1.12e-39	-	-	-	S	ko:K07133	-	ko00000	ATPase (AAA superfamily)
HAPAPPHC_01326	3.76e-213	-	-	-	S	ko:K07133	-	ko00000	ATPase (AAA superfamily)
HAPAPPHC_01328	1.6e-146	-	-	-	L	-	-	-	DNA-binding protein
HAPAPPHC_01329	1.16e-60	-	-	-	-	-	-	-	-
HAPAPPHC_01331	0.0	-	-	-	G	-	-	-	Bacterial alpha-L-rhamnosidase C-terminal domain
HAPAPPHC_01332	0.0	-	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HAPAPPHC_01333	0.0	-	-	-	G	-	-	-	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HAPAPPHC_01334	8.42e-194	rhaD	4.1.2.19	-	G	ko:K01629	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Class II Aldolase and Adducin N-terminal domain
HAPAPPHC_01335	6.75e-245	rhaT	-	-	EG	ko:K02856	-	ko00000,ko02000	L-rhamnose-proton symport protein (RhaT)
HAPAPPHC_01336	1.81e-313	rhaA	5.3.1.14	-	G	ko:K01813	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	L-rhamnose isomerase (RhaA)
HAPAPPHC_01337	1.88e-287	rhaB	2.7.1.5, 2.7.1.51	-	G	ko:K00848,ko:K00879	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	FGGY family of carbohydrate kinases, N-terminal domain
HAPAPPHC_01338	2.03e-220	-	-	-	K	-	-	-	AraC-like ligand binding domain
HAPAPPHC_01339	0.0	-	-	-	S	ko:K09955	-	ko00000	Beta-L-arabinofuranosidase, GH127
HAPAPPHC_01340	0.0	-	-	-	T	-	-	-	Histidine kinase-like ATPases
HAPAPPHC_01341	1.54e-275	-	3.4.13.19	-	E	ko:K01273	-	ko00000,ko00537,ko01000,ko01002,ko04147	Membrane dipeptidase (Peptidase family M19)
HAPAPPHC_01342	3.12e-274	-	-	-	E	-	-	-	Putative serine dehydratase domain
HAPAPPHC_01343	7.91e-112	-	-	-	J	-	-	-	YjgF/chorismate_mutase-like, putative endoribonuclease
HAPAPPHC_01344	2.52e-124	-	-	-	I	-	-	-	Domain of unknown function (DUF4833)
HAPAPPHC_01345	2.23e-283	gntT	-	-	EG	ko:K06155	-	ko00000,ko02000	GntP family permease
HAPAPPHC_01346	2.18e-247	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
HAPAPPHC_01347	7.94e-233	ybhS	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
HAPAPPHC_01348	1.44e-149	-	-	-	G	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HAPAPPHC_01349	5.32e-218	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HAPAPPHC_01350	1.35e-205	-	-	-	M	ko:K01993	-	ko00000	HlyD family secretion protein
HAPAPPHC_01351	1.18e-293	-	-	-	MU	-	-	-	Outer membrane efflux protein
HAPAPPHC_01352	1.9e-139	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HAPAPPHC_01353	1.01e-260	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
HAPAPPHC_01354	4.36e-290	sdaA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase
HAPAPPHC_01355	1.97e-278	-	-	-	S	-	-	-	COGs COG4299 conserved
HAPAPPHC_01356	7.65e-273	-	-	-	S	-	-	-	Domain of unknown function (DUF5009)
HAPAPPHC_01357	3.51e-62	-	-	-	S	-	-	-	Predicted AAA-ATPase
HAPAPPHC_01358	9.06e-181	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
HAPAPPHC_01359	0.0	-	-	-	C	-	-	-	B12 binding domain
HAPAPPHC_01360	2.61e-39	-	-	-	I	-	-	-	acyltransferase
HAPAPPHC_01361	3.15e-63	-	-	-	M	-	-	-	Glycosyl transferases group 1
HAPAPPHC_01362	8.78e-219	-	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	UDP-N-acetylglucosamine 2-epimerase
HAPAPPHC_01363	5.22e-40	wbcM	-	-	M	-	-	-	Glycosyl transferases group 1
HAPAPPHC_01365	6.51e-57	wbcM	-	-	M	-	-	-	Glycosyl transferases group 1
HAPAPPHC_01367	3.45e-248	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HAPAPPHC_01368	3.54e-50	-	-	-	S	-	-	-	Nucleotidyltransferase domain
HAPAPPHC_01369	3.05e-152	-	-	-	M	-	-	-	sugar transferase
HAPAPPHC_01372	7.18e-86	-	-	-	-	-	-	-	-
HAPAPPHC_01373	1.67e-236	-	-	-	K	-	-	-	Participates in transcription elongation, termination and antitermination
HAPAPPHC_01374	2.46e-220	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
HAPAPPHC_01375	0.0	cobQ	6.3.5.10	-	H	ko:K02232	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
HAPAPPHC_01376	0.0	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HAPAPPHC_01377	1.12e-116	-	1.16.3.1	-	S	ko:K03594	ko00860,map00860	ko00000,ko00001,ko01000	Ferritin-like domain
HAPAPPHC_01378	9.65e-135	thiJ	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	biosynthesis protein ThiJ
HAPAPPHC_01379	6.61e-210	-	-	-	T	-	-	-	Histidine kinase-like ATPases
HAPAPPHC_01380	0.0	paaK	6.2.1.30	-	H	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	ko00000,ko00001,ko01000	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
HAPAPPHC_01381	5.43e-90	-	-	-	S	-	-	-	ACT domain protein
HAPAPPHC_01382	2.24e-19	-	-	-	-	-	-	-	-
HAPAPPHC_01383	0.0	-	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HAPAPPHC_01384	5.03e-137	-	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HAPAPPHC_01385	0.0	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HAPAPPHC_01386	0.0	-	-	-	T	-	-	-	His Kinase A (phospho-acceptor) domain
HAPAPPHC_01387	0.0	yhgF	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain
HAPAPPHC_01388	1.68e-109	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HAPAPPHC_01389	7.02e-94	-	-	-	S	-	-	-	Lipocalin-like domain
HAPAPPHC_01390	7.88e-131	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
HAPAPPHC_01392	3.44e-199	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HAPAPPHC_01393	2.15e-199	pheA	4.2.1.51	-	E	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
HAPAPPHC_01394	8.26e-294	dapL	2.6.1.83	-	E	ko:K10206,ko:K14261	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
HAPAPPHC_01395	2.32e-259	pheB	5.4.99.5	-	E	ko:K04516	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cytochrome C4
HAPAPPHC_01396	1.97e-183	tyrA	1.3.1.12	-	E	ko:K00210	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydrogenase
HAPAPPHC_01397	1.2e-262	-	-	-	V	-	-	-	MatE
HAPAPPHC_01398	1.91e-28	-	-	-	V	-	-	-	MatE
HAPAPPHC_01399	4.8e-128	-	-	-	T	-	-	-	Cyclic nucleotide-binding domain
HAPAPPHC_01400	0.0	norM	-	-	V	ko:K03327	-	ko00000,ko02000	Mate efflux family protein
HAPAPPHC_01401	0.0	-	-	-	EGP	ko:K08169	-	ko00000,ko02000	Major Facilitator Superfamily
HAPAPPHC_01402	0.0	zraR_2	-	-	T	-	-	-	COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains
HAPAPPHC_01403	1e-33	-	-	-	T	-	-	-	Histidine kinase
HAPAPPHC_01404	5.91e-267	-	-	-	T	-	-	-	Histidine kinase
HAPAPPHC_01405	1.16e-283	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	Natural resistance-associated macrophage protein
HAPAPPHC_01406	0.0	glnS	6.1.1.18	-	J	ko:K01886	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
HAPAPPHC_01407	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
HAPAPPHC_01408	2.26e-213	-	-	-	S	ko:K08974	-	ko00000	Domain of unknown function (DUF368)
HAPAPPHC_01410	6.06e-36	-	1.2.7.3	-	C	ko:K00176	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	br01601,ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
HAPAPPHC_01411	2.41e-258	vorB	1.2.7.11, 1.2.7.3	-	C	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the coenzyme A-dependent oxidation of 3-methyl-2-oxobutanoate coupled to the reduction of ferredoxin producing S-(2-methylpropanoyl)-CoA
HAPAPPHC_01412	1.19e-18	-	-	-	-	-	-	-	-
HAPAPPHC_01413	2.82e-186	vorA	1.2.7.11, 1.2.7.3	-	C	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Oxidoreductase
HAPAPPHC_01414	1.68e-121	porG	1.2.7.3	-	C	ko:K00177	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	br01601,ko00000,ko00001,ko00002,ko01000	2-oxoglutarate ferredoxin oxidoreductase subunit gamma
HAPAPPHC_01415	0.0	-	-	-	H	-	-	-	Putative porin
HAPAPPHC_01416	3.54e-190	-	-	-	M	-	-	-	Bacterial extracellular solute-binding proteins, family 3
HAPAPPHC_01417	0.0	-	-	-	T	-	-	-	PAS fold
HAPAPPHC_01418	7.28e-302	-	-	-	L	-	-	-	Belongs to the DEAD box helicase family
HAPAPPHC_01419	0.0	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HAPAPPHC_01420	0.0	tilS	6.3.4.19	-	D	ko:K04075	-	ko00000,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HAPAPPHC_01421	1.84e-120	-	-	-	S	ko:K07164	-	ko00000	Zinc ribbon domain protein
HAPAPPHC_01422	5.78e-269	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HAPAPPHC_01423	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HAPAPPHC_01424	3.89e-09	-	-	-	-	-	-	-	-
HAPAPPHC_01425	1.16e-127	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
HAPAPPHC_01427	5.75e-122	-	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HAPAPPHC_01428	3.88e-166	-	-	-	GM	-	-	-	NAD dependent epimerase/dehydratase family
HAPAPPHC_01429	9.85e-240	rfbG	4.2.1.45	-	M	ko:K01709	ko00520,map00520	ko00000,ko00001,ko01000	Polysaccharide biosynthesis protein
HAPAPPHC_01430	2.73e-174	rfbF	2.7.7.33	-	JM	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	ko00000,ko00001,ko01000	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon)
HAPAPPHC_01431	7.54e-100	licD	-	-	M	ko:K07271	-	ko00000,ko01000	LicD family
HAPAPPHC_01432	4.31e-63	-	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Cytidylyltransferase
HAPAPPHC_01433	3.54e-36	-	-	-	M	-	-	-	Glycosyltransferase, group 1 family protein
HAPAPPHC_01434	1.5e-29	-	-	-	-	-	-	-	-
HAPAPPHC_01436	1.06e-100	-	-	-	M	-	-	-	Glycosyl transferases group 1
HAPAPPHC_01437	2.89e-57	-	-	-	S	-	-	-	PFAM polysaccharide biosynthesis protein
HAPAPPHC_01438	1.72e-54	-	-	-	S	-	-	-	Polysaccharide biosynthesis protein
HAPAPPHC_01442	2.87e-167	-	-	-	S	-	-	-	Domain of unknown function (DUF4469) with IG-like fold
HAPAPPHC_01443	1.2e-142	-	-	-	M	-	-	-	sugar transferase
HAPAPPHC_01444	4.29e-88	-	-	-	-	-	-	-	-
HAPAPPHC_01445	2.98e-269	-	-	-	K	-	-	-	Participates in transcription elongation, termination and antitermination
HAPAPPHC_01446	4.63e-225	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
HAPAPPHC_01447	0.0	-	-	-	G	-	-	-	Glycosyl hydrolases family 2
HAPAPPHC_01448	6.46e-66	-	-	-	L	-	-	-	ABC transporter
HAPAPPHC_01449	3.7e-236	-	-	-	S	-	-	-	Trehalose utilisation
HAPAPPHC_01450	6.99e-115	-	-	-	-	-	-	-	-
HAPAPPHC_01452	1.94e-278	-	-	-	G	-	-	-	Glycosyl hydrolase family 20, catalytic domain
HAPAPPHC_01453	1.09e-134	-	-	-	S	-	-	-	Hexapeptide repeat of succinyl-transferase
HAPAPPHC_01454	3.13e-222	-	-	-	K	-	-	-	Transcriptional regulator
HAPAPPHC_01456	0.0	alaC	-	-	E	-	-	-	Aminotransferase
HAPAPPHC_01457	7.04e-150	-	-	-	K	ko:K07735	-	ko00000,ko03000	Uncharacterized ACR, COG1678
HAPAPPHC_01458	8.82e-124	speG	2.3.1.57	-	J	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	ko00000,ko00001,ko00002,ko01000	Acetyltransferase (GNAT) domain
HAPAPPHC_01459	3.59e-286	wbbL	-	-	S	ko:K07011	-	ko00000	Glycosyl transferase family group 2
HAPAPPHC_01460	2.78e-121	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HAPAPPHC_01461	0.0	-	-	-	S	-	-	-	Peptide transporter
HAPAPPHC_01462	0.0	lytB	-	-	D	ko:K06381	-	ko00000	Stage II sporulation protein
HAPAPPHC_01463	7.16e-100	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HAPAPPHC_01464	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HAPAPPHC_01465	0.0	-	3.1.3.5, 3.6.1.45	-	F	ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HAPAPPHC_01466	0.0	-	-	-	E	-	-	-	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HAPAPPHC_01467	7e-142	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
HAPAPPHC_01468	0.0	-	-	-	C	-	-	-	Elongator protein 3, MiaB family, Radical SAM
HAPAPPHC_01469	0.0	-	-	-	P	ko:K16089	-	ko00000,ko02000	TonB-dependent receptor
HAPAPPHC_01470	6.59e-48	-	-	-	-	-	-	-	-
HAPAPPHC_01471	0.0	-	-	-	P	ko:K07085	-	ko00000	TrkA C-terminal domain protein
HAPAPPHC_01472	0.0	-	-	-	V	-	-	-	ABC-2 type transporter
HAPAPPHC_01474	3.87e-264	-	-	-	J	-	-	-	(SAM)-dependent
HAPAPPHC_01475	0.0	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
HAPAPPHC_01476	3.04e-303	LYS1	1.5.1.7	-	E	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Saccharopine dehydrogenase
HAPAPPHC_01477	1.25e-107	bcp	1.11.1.15	-	O	ko:K03564	-	ko00000,ko01000	Thiol peroxidase
HAPAPPHC_01478	4.39e-245	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HAPAPPHC_01479	1.74e-191	-	-	-	V	-	-	-	Acetyltransferase (GNAT) domain
HAPAPPHC_01480	3.12e-176	-	-	-	G	-	-	-	polysaccharide deacetylase
HAPAPPHC_01481	2.94e-122	-	-	-	G	-	-	-	polysaccharide deacetylase
HAPAPPHC_01482	4.7e-150	-	-	-	S	-	-	-	GlcNAc-PI de-N-acetylase
HAPAPPHC_01483	9.93e-307	-	-	-	M	-	-	-	Glycosyltransferase Family 4
HAPAPPHC_01484	1.33e-283	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HAPAPPHC_01485	5.18e-251	prmA	2.1.1.222, 2.1.1.64	-	J	ko:K00568,ko:K02687	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko03009	protein methyltransferase activity
HAPAPPHC_01486	1.03e-96	folK2	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HAPAPPHC_01487	1.85e-112	-	-	-	-	-	-	-	-
HAPAPPHC_01488	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
HAPAPPHC_01489	3e-314	-	-	-	S	-	-	-	acid phosphatase activity
HAPAPPHC_01490	0.0	ugd	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HAPAPPHC_01491	2.05e-230	-	4.3.1.12	-	E	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	ko00000,ko00001,ko01000	Ornithine cyclodeaminase/mu-crystallin family
HAPAPPHC_01492	3.37e-250	-	-	-	M	-	-	-	Nucleotidyl transferase
HAPAPPHC_01493	1.84e-165	-	-	-	M	-	-	-	Nucleotidyl transferase
HAPAPPHC_01494	2.05e-282	-	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HAPAPPHC_01495	6.27e-99	-	-	-	S	-	-	-	regulation of response to stimulus
HAPAPPHC_01496	4.44e-167	-	-	-	S	-	-	-	regulation of response to stimulus
HAPAPPHC_01498	6.9e-297	-	-	-	M	-	-	-	-O-antigen
HAPAPPHC_01499	2.25e-297	-	-	-	M	-	-	-	Glycosyltransferase Family 4
HAPAPPHC_01500	8.5e-268	-	-	-	M	-	-	-	Glycosyltransferase
HAPAPPHC_01501	1.09e-220	-	-	-	M	ko:K07271	-	ko00000,ko01000	LICD family
HAPAPPHC_01502	2.46e-186	-	-	-	M	-	-	-	Chain length determinant protein
HAPAPPHC_01503	4e-130	-	-	-	M	-	-	-	Chain length determinant protein
HAPAPPHC_01504	1.53e-180	-	-	-	M	ko:K01991	ko02026,map02026	ko00000,ko00001,ko02000	Polysaccharide biosynthesis/export protein
HAPAPPHC_01505	8.49e-205	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
HAPAPPHC_01506	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HAPAPPHC_01507	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeats
HAPAPPHC_01508	1.3e-126	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HAPAPPHC_01510	2.8e-135	rbr3A	-	-	C	-	-	-	Rubrerythrin
HAPAPPHC_01511	1.19e-259	fbaB	4.1.2.13	-	G	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	DeoC/LacD family aldolase
HAPAPPHC_01512	0.0	pop	-	-	EU	-	-	-	peptidase
HAPAPPHC_01513	5.37e-107	-	-	-	D	-	-	-	cell division
HAPAPPHC_01514	2.88e-186	-	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family
HAPAPPHC_01515	0.0	-	-	-	T	-	-	-	Periplasmic binding proteins and sugar binding domain of LacI family
HAPAPPHC_01516	1.43e-219	-	-	-	-	-	-	-	-
HAPAPPHC_01517	0.0	-	-	-	M	-	-	-	MBOAT, membrane-bound O-acyltransferase family
HAPAPPHC_01518	9.44e-109	-	-	-	G	-	-	-	Cupin 2, conserved barrel domain protein
HAPAPPHC_01519	4.18e-197	-	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HAPAPPHC_01520	8.73e-253	prtQ	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Collagenase
HAPAPPHC_01521	1.34e-143	prtQ	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Collagenase
HAPAPPHC_01522	7.31e-18	prtQ	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Collagenase
HAPAPPHC_01523	6.39e-49	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HAPAPPHC_01524	4.73e-115	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HAPAPPHC_01525	2.47e-106	-	-	-	S	-	-	-	6-bladed beta-propeller
HAPAPPHC_01526	2.83e-312	-	-	-	MU	ko:K18139,ko:K18300	ko01501,ko02024,map01501,map02024	ko00000,ko00001,ko00002,ko01504,ko02000	Outer membrane efflux protein
HAPAPPHC_01527	1.43e-105	-	-	-	V	-	-	-	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HAPAPPHC_01528	0.0	-	-	-	V	-	-	-	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HAPAPPHC_01529	3.26e-257	-	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HAPAPPHC_01530	1.77e-165	rluC	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Pseudouridine synthase
HAPAPPHC_01531	1e-167	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
HAPAPPHC_01532	7.42e-228	-	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal
HAPAPPHC_01533	2.85e-135	qacR	-	-	K	-	-	-	tetR family
HAPAPPHC_01535	0.0	-	-	-	V	-	-	-	Beta-lactamase
HAPAPPHC_01536	2.24e-96	-	-	-	Q	-	-	-	Domain of unknown function (DUF4442)
HAPAPPHC_01537	5.38e-131	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HAPAPPHC_01538	1.42e-263	pbuX	-	-	F	ko:K16345	-	ko00000,ko02000	Permease family
HAPAPPHC_01539	0.0	-	-	-	S	-	-	-	Endonuclease/Exonuclease/phosphatase family
HAPAPPHC_01540	7.65e-250	ltaE	4.1.2.48	-	E	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Threonine aldolase
HAPAPPHC_01542	4.36e-05	-	-	-	-	-	-	-	-
HAPAPPHC_01543	2.66e-253	-	-	-	S	-	-	-	Large extracellular alpha-helical protein
HAPAPPHC_01544	2.32e-111	-	-	-	S	-	-	-	Large extracellular alpha-helical protein
HAPAPPHC_01545	1.21e-292	-	-	-	S	-	-	-	Domain of unknown function (DUF4249)
HAPAPPHC_01546	0.0	-	-	-	P	-	-	-	TonB-dependent receptor plug domain
HAPAPPHC_01547	3.02e-160	-	-	-	-	-	-	-	-
HAPAPPHC_01549	0.0	-	-	-	S	-	-	-	VirE N-terminal domain
HAPAPPHC_01550	2.66e-65	-	-	-	L	-	-	-	regulation of translation
HAPAPPHC_01551	1.28e-192	-	-	-	S	-	-	-	Toxin-antitoxin system, toxin component, Fic
HAPAPPHC_01552	1.83e-99	-	-	-	L	-	-	-	regulation of translation
HAPAPPHC_01553	5.79e-117	-	-	-	NU	ko:K02395	-	ko00000,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HAPAPPHC_01554	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	Pfam:SusD
HAPAPPHC_01555	5.43e-49	-	-	-	S	ko:K21572	-	ko00000,ko02000	Pfam:SusD
HAPAPPHC_01556	0.0	-	-	-	P	-	-	-	TonB dependent receptor
HAPAPPHC_01557	0.0	bga	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Glycosyl hydrolases family 35
HAPAPPHC_01558	5.01e-177	bga	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Glycosyl hydrolases family 35
HAPAPPHC_01559	1.42e-58	pfp	2.7.1.11, 2.7.1.90	-	H	ko:K00895,ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions
HAPAPPHC_01560	5.82e-289	pfp	2.7.1.11, 2.7.1.90	-	H	ko:K00895,ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions
HAPAPPHC_01562	5.07e-50	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HAPAPPHC_01563	1.22e-09	-	-	-	NU	-	-	-	CotH kinase protein
HAPAPPHC_01569	5.2e-204	-	-	-	CO	-	-	-	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HAPAPPHC_01570	2.31e-83	-	-	-	O	ko:K07397	-	ko00000	OsmC-like protein
HAPAPPHC_01571	5.63e-179	-	-	-	Q	-	-	-	Alkyl sulfatase dimerisation
HAPAPPHC_01572	2.22e-71	-	-	-	Q	-	-	-	Alkyl sulfatase dimerisation
HAPAPPHC_01573	2.93e-167	-	-	-	C	-	-	-	COG0822 NifU homolog involved in Fe-S cluster formation
HAPAPPHC_01574	1.42e-31	-	-	-	-	-	-	-	-
HAPAPPHC_01575	1.78e-240	-	-	-	S	-	-	-	GGGtGRT protein
HAPAPPHC_01576	2.1e-188	-	-	-	C	-	-	-	4Fe-4S dicluster domain
HAPAPPHC_01577	9.24e-37	-	-	-	S	-	-	-	COG NOG17973 non supervised orthologous group
HAPAPPHC_01579	4.73e-102	nlpE	-	-	MP	-	-	-	NlpE N-terminal domain
HAPAPPHC_01580	0.0	-	-	-	S	-	-	-	ATPases associated with a variety of cellular activities
HAPAPPHC_01581	8.38e-170	-	-	-	E	ko:K04477	-	ko00000	DNA polymerase alpha chain like domain
HAPAPPHC_01582	1.06e-204	-	-	-	O	-	-	-	Tetratricopeptide repeat protein
HAPAPPHC_01583	1.49e-121	-	-	-	O	-	-	-	Tetratricopeptide repeat protein
HAPAPPHC_01584	7.13e-169	-	-	-	S	-	-	-	Beta-lactamase superfamily domain
HAPAPPHC_01585	0.0	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
HAPAPPHC_01586	3.74e-219	-	-	-	M	ko:K01993	-	ko00000	Biotin-lipoyl like
HAPAPPHC_01587	3.22e-50	-	-	-	MU	-	-	-	Outer membrane efflux protein
HAPAPPHC_01588	1.02e-250	-	-	-	MU	-	-	-	Outer membrane efflux protein
HAPAPPHC_01589	8.45e-222	fsr	-	-	G	ko:K08223	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HAPAPPHC_01590	5.25e-129	-	-	-	T	-	-	-	FHA domain protein
HAPAPPHC_01591	0.0	-	-	-	T	-	-	-	PAS domain
HAPAPPHC_01592	1.6e-216	thiD	2.7.1.49, 2.7.4.7	-	K	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	transcriptional regulator (AraC family)
HAPAPPHC_01595	1.98e-09	-	-	-	S	-	-	-	Tetratricopeptide repeat protein
HAPAPPHC_01596	1.28e-233	-	-	-	M	-	-	-	glycosyl transferase family 2
HAPAPPHC_01597	3.72e-205	nadK	2.7.1.23	-	H	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HAPAPPHC_01598	4.3e-150	-	-	-	S	-	-	-	CBS domain
HAPAPPHC_01599	1.83e-174	pdxJ	2.6.99.2	-	H	ko:K03474	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HAPAPPHC_01600	1.32e-157	exbB	-	-	U	ko:K03561	-	ko00000,ko02000	Transporter, MotA TolQ ExbB proton channel family protein
HAPAPPHC_01601	2.43e-86	-	-	-	U	ko:K03559	-	ko00000,ko02000	Biopolymer transporter ExbD
HAPAPPHC_01602	2.42e-140	-	-	-	M	-	-	-	TonB family domain protein
HAPAPPHC_01603	1.55e-122	yajL	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	Thiamine biosynthesis protein ThiJ
HAPAPPHC_01604	1.27e-261	-	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
HAPAPPHC_01605	5.06e-208	-	-	-	EG	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HAPAPPHC_01606	1.8e-191	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the MenA family. Type 1 subfamily
HAPAPPHC_01610	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	MFS/sugar transport protein
HAPAPPHC_01611	1.03e-241	cytR	-	-	K	ko:K02529,ko:K05499	-	ko00000,ko03000	PFAM periplasmic binding protein LacI transcriptional regulator
HAPAPPHC_01612	0.0	susC	-	-	P	ko:K21573	-	ko00000,ko02000	CarboxypepD_reg-like domain
HAPAPPHC_01613	0.0	susD	-	-	M	ko:K21572	-	ko00000,ko02000	SusD family
HAPAPPHC_01614	9.34e-277	-	-	-	S	ko:K21571	-	ko00000	Outer membrane protein SusF_SusE
HAPAPPHC_01615	1.82e-45	-	-	-	S	-	-	-	Winged helix-turn-helix domain (DUF2582)
HAPAPPHC_01616	3.69e-203	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HAPAPPHC_01617	1.86e-192	-	-	-	G	-	-	-	alpha-galactosidase
HAPAPPHC_01618	0.0	pepO	3.4.24.71	-	O	ko:K01415,ko:K07386	-	ko00000,ko01000,ko01002,ko04147	Peptidase family M13
HAPAPPHC_01619	0.0	abf2	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	Alpha-L-arabinofuranosidase C-terminus
HAPAPPHC_01620	1.27e-221	-	-	-	M	-	-	-	nucleotidyltransferase
HAPAPPHC_01621	2.92e-259	-	-	-	S	-	-	-	Alpha/beta hydrolase family
HAPAPPHC_01622	6.43e-284	-	-	-	C	-	-	-	related to aryl-alcohol
HAPAPPHC_01623	0.0	-	-	-	S	-	-	-	ARD/ARD' family
HAPAPPHC_01624	1.02e-159	ppiA	5.2.1.8	-	M	ko:K01802,ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HAPAPPHC_01625	1.55e-174	ppiA	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HAPAPPHC_01626	3.94e-256	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HAPAPPHC_01627	0.0	-	-	-	M	-	-	-	CarboxypepD_reg-like domain
HAPAPPHC_01628	3.2e-208	-	-	-	M	-	-	-	CarboxypepD_reg-like domain
HAPAPPHC_01629	0.0	fkp	-	-	S	-	-	-	L-fucokinase
HAPAPPHC_01630	4.66e-140	-	-	-	L	-	-	-	Resolvase, N terminal domain
HAPAPPHC_01631	1.84e-105	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
HAPAPPHC_01632	2.86e-287	-	-	-	M	-	-	-	glycosyl transferase group 1
HAPAPPHC_01633	6e-42	-	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	UDP-N-acetylglucosamine 2-epimerase
HAPAPPHC_01634	3.88e-223	-	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	UDP-N-acetylglucosamine 2-epimerase
HAPAPPHC_01635	4.47e-298	-	1.1.1.336	-	M	ko:K02472	ko00520,ko05111,map00520,map05111	ko00000,ko00001,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HAPAPPHC_01636	1.8e-297	-	-	-	S	-	-	-	Heparinase II/III N-terminus
HAPAPPHC_01637	0.0	-	-	-	E	ko:K02030,ko:K03810	-	ko00000,ko00002,ko02000	Oxidoreductase NAD-binding domain protein
HAPAPPHC_01638	1.17e-94	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HAPAPPHC_01640	3.12e-250	-	2.4.1.348	GT4	M	ko:K12995	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 1 family protein
HAPAPPHC_01641	4.42e-21	-	-	-	-	-	-	-	-
HAPAPPHC_01642	2.16e-114	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HAPAPPHC_01643	1.68e-105	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HAPAPPHC_01644	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HAPAPPHC_01645	1.12e-83	-	-	-	S	-	-	-	Protein of unknown function DUF86
HAPAPPHC_01646	1.02e-59	-	-	-	S	ko:K07075	-	ko00000	Nucleotidyltransferase domain
HAPAPPHC_01647	1.75e-100	-	-	-	-	-	-	-	-
HAPAPPHC_01648	1.55e-134	-	-	-	S	-	-	-	VirE N-terminal domain
HAPAPPHC_01649	0.0	-	-	-	L	-	-	-	Primase C terminal 2 (PriCT-2)
HAPAPPHC_01650	6.14e-10	-	-	-	S	-	-	-	Domain of unknown function (DUF4248)
HAPAPPHC_01651	3.34e-107	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
HAPAPPHC_01653	0.000452	-	-	-	-	-	-	-	-
HAPAPPHC_01654	2.35e-110	-	3.5.1.28	-	V	ko:K01447	-	ko00000,ko01000	Ami_2
HAPAPPHC_01655	5.92e-164	-	-	-	M	-	-	-	sugar transferase
HAPAPPHC_01656	1.1e-90	-	-	-	-	-	-	-	-
HAPAPPHC_01657	2.87e-270	-	-	-	K	-	-	-	Participates in transcription elongation, termination and antitermination
HAPAPPHC_01658	1.01e-223	-	-	-	L	-	-	-	COG NOG11942 non supervised orthologous group
HAPAPPHC_01659	1.26e-112	-	-	-	S	-	-	-	Phage tail protein
HAPAPPHC_01660	2.14e-156	yggS	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HAPAPPHC_01661	8.07e-233	-	1.3.98.1	-	F	ko:K00226	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dihydroorotate to orotate
HAPAPPHC_01662	1e-80	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HAPAPPHC_01663	0.0	cdr	-	-	P	-	-	-	Belongs to the sulfur carrier protein TusA family
HAPAPPHC_01664	1.01e-37	-	-	-	K	-	-	-	-acetyltransferase
HAPAPPHC_01665	1.2e-07	-	-	-	-	-	-	-	-
HAPAPPHC_01666	2.89e-60	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	seryl-tRNA synthetase
HAPAPPHC_01667	2.07e-230	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	seryl-tRNA synthetase
HAPAPPHC_01668	1.45e-126	mepS	3.4.17.13	-	M	ko:K13694	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
HAPAPPHC_01669	3.67e-164	-	-	-	KT	-	-	-	LytTr DNA-binding domain
HAPAPPHC_01670	1.61e-251	-	-	-	T	-	-	-	Histidine kinase
HAPAPPHC_01671	0.0	-	3.2.1.20	GH31	M	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl-hydrolase 97 C-terminal, oligomerisation
HAPAPPHC_01672	0.0	-	-	-	E	-	-	-	N-terminus of Esterase_SGNH_hydro-type
HAPAPPHC_01673	7.15e-122	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
HAPAPPHC_01674	8.86e-244	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HAPAPPHC_01675	3.07e-91	-	-	-	S	-	-	-	TamB, inner membrane protein subunit of TAM complex
HAPAPPHC_01676	0.0	-	-	-	S	-	-	-	TamB, inner membrane protein subunit of TAM complex
HAPAPPHC_01677	0.0	-	-	-	S	-	-	-	TamB, inner membrane protein subunit of TAM complex
HAPAPPHC_01678	1.13e-220	dus	-	-	H	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HAPAPPHC_01679	1.24e-159	lipB	2.3.1.181	-	H	ko:K03801	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate
HAPAPPHC_01680	9.06e-189	mtgA	2.4.1.129	GT51	M	ko:K03814	ko00550,map00550	ko00000,ko00001,ko01000,ko01003,ko01011	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HAPAPPHC_01681	0.0	-	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
HAPAPPHC_01682	5.31e-115	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HAPAPPHC_01683	0.0	-	-	-	O	ko:K07403	-	ko00000	serine protease
HAPAPPHC_01684	4.7e-150	-	-	-	K	-	-	-	Putative DNA-binding domain
HAPAPPHC_01685	0.0	-	-	-	P	ko:K03455	-	ko00000	COG0475 Kef-type K transport systems, membrane components
HAPAPPHC_01686	3.28e-181	kdsB	2.7.7.38	-	M	ko:K00979	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
HAPAPPHC_01687	0.0	-	-	-	-	-	-	-	-
HAPAPPHC_01688	0.0	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins
HAPAPPHC_01689	4.41e-306	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HAPAPPHC_01690	2.04e-68	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HAPAPPHC_01691	0.0	-	-	-	M	-	-	-	Protein of unknown function (DUF3078)
HAPAPPHC_01692	1.57e-92	-	-	-	T	ko:K03803	-	ko00000,ko03021	Positive regulator of sigma(E), RseC MucC
HAPAPPHC_01693	9.77e-206	rnfB	-	-	C	ko:K03616	-	ko00000	Ferredoxin
HAPAPPHC_01694	1.55e-277	rnfC	-	-	C	ko:K03615	-	ko00000	Part of a membrane complex involved in electron transport
HAPAPPHC_01695	1.88e-225	rnfD	-	-	C	ko:K03614	-	ko00000	Part of a membrane complex involved in electron transport
HAPAPPHC_01696	2.86e-129	rnfG	-	-	C	ko:K03612	-	ko00000	Part of a membrane complex involved in electron transport
HAPAPPHC_01697	6.43e-126	rnfE	-	-	C	ko:K03613	-	ko00000	Part of a membrane complex involved in electron transport
HAPAPPHC_01698	4.19e-120	rnfA	-	-	C	ko:K03617	-	ko00000	Part of a membrane complex involved in electron transport
HAPAPPHC_01699	7.68e-253	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HAPAPPHC_01700	0.0	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
HAPAPPHC_01701	1.63e-88	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
HAPAPPHC_01702	8.43e-126	-	3.1.3.10, 3.1.3.104	-	S	ko:K07025,ko:K20866,ko:K21063	ko00010,ko00740,ko01100,ko01110,ko01120,map00010,map00740,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	HAD hydrolase, family IA, variant 3
HAPAPPHC_01703	2.99e-310	-	-	-	S	-	-	-	Protein of unknown function (DUF1015)
HAPAPPHC_01704	1.01e-185	serA	1.1.1.399, 1.1.1.95	-	CH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HAPAPPHC_01705	2.5e-258	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HAPAPPHC_01706	2.63e-301	rarA	-	-	L	ko:K07478	-	ko00000	ATPase (AAA
HAPAPPHC_01707	4.33e-197	-	-	-	H	-	-	-	COG NOG26372 non supervised orthologous group
HAPAPPHC_01708	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HAPAPPHC_01709	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HAPAPPHC_01710	1.65e-299	-	-	-	H	-	-	-	Susd and RagB outer membrane lipoprotein
HAPAPPHC_01711	1.29e-231	-	-	-	L	-	-	-	Arm DNA-binding domain
HAPAPPHC_01712	0.0	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
HAPAPPHC_01713	2.03e-14	-	-	-	L	-	-	-	Arm DNA-binding domain
HAPAPPHC_01714	1.69e-119	-	-	-	S	-	-	-	Lipid-binding putative hydrolase
HAPAPPHC_01715	0.0	-	-	-	S	-	-	-	Susd and RagB outer membrane lipoprotein
HAPAPPHC_01716	0.0	-	-	-	P	-	-	-	TonB dependent receptor
HAPAPPHC_01717	0.0	-	-	-	P	-	-	-	TonB-dependent Receptor Plug Domain
HAPAPPHC_01718	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	Pfam:SusD
HAPAPPHC_01719	0.0	modF	-	-	P	ko:K05776	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
HAPAPPHC_01720	0.0	-	-	-	S	-	-	-	Susd and RagB outer membrane lipoprotein
HAPAPPHC_01721	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HAPAPPHC_01722	4.03e-170	-	-	-	C	-	-	-	Domain of Unknown Function (DUF1080)
HAPAPPHC_01723	1.05e-177	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
HAPAPPHC_01725	5.87e-300	-	-	-	S	-	-	-	Domain of unknown function (DUF4105)
HAPAPPHC_01726	0.0	pafA	-	-	P	-	-	-	Type I phosphodiesterase / nucleotide pyrophosphatase
HAPAPPHC_01727	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HAPAPPHC_01728	5.27e-260	ald	1.4.1.1	-	C	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Alanine dehydrogenase/PNT, N-terminal domain
HAPAPPHC_01729	3.53e-172	-	-	-	S	ko:K02651	ko04112,map04112	ko00000,ko00001,ko02035,ko02044	COG NOG28004 non supervised orthologous group
HAPAPPHC_01730	2.3e-176	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
HAPAPPHC_01731	1.96e-132	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
HAPAPPHC_01732	3e-271	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HAPAPPHC_01733	5.51e-205	nlpD_1	-	-	M	-	-	-	Peptidase family M23
HAPAPPHC_01734	3.41e-64	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HAPAPPHC_01735	3.96e-311	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HAPAPPHC_01736	2.26e-143	-	-	-	S	-	-	-	Domain of unknown function (DUF4290)
HAPAPPHC_01737	8.15e-113	yncA	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
HAPAPPHC_01738	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 2 family
HAPAPPHC_01739	1.11e-31	-	-	-	-	-	-	-	-
HAPAPPHC_01741	3.32e-204	-	-	-	S	-	-	-	Protein of unknown function (DUF3298)
HAPAPPHC_01742	4.74e-159	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
HAPAPPHC_01743	3.87e-154	-	-	-	P	-	-	-	metallo-beta-lactamase
HAPAPPHC_01744	0.0	gcvP	1.4.4.2	-	E	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the GcvP family
HAPAPPHC_01745	5.73e-286	-	-	-	S	-	-	-	PFAM Uncharacterised BCR, COG1649
HAPAPPHC_01746	0.0	dtpD	-	-	E	-	-	-	POT family
HAPAPPHC_01747	8.22e-102	-	-	-	K	-	-	-	Transcriptional regulator
HAPAPPHC_01748	5.77e-214	etfB	-	-	C	ko:K03521	-	ko00000	Electron transfer flavoprotein
HAPAPPHC_01749	1.86e-245	etfA	-	-	C	ko:K03522	-	ko00000,ko04147	Electron transfer flavoprotein
HAPAPPHC_01750	0.0	acd	-	-	C	-	-	-	acyl-CoA dehydrogenase
HAPAPPHC_01751	1.36e-303	dinF	-	-	V	ko:K03327	-	ko00000,ko02000	Mate efflux family protein
HAPAPPHC_01752	5.59e-273	-	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
HAPAPPHC_01753	8.84e-140	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HAPAPPHC_01754	2.74e-285	rmuC	-	-	S	ko:K09760	-	ko00000	RmuC family
HAPAPPHC_01755	0.0	-	-	-	S	-	-	-	AbgT putative transporter family
HAPAPPHC_01756	7.23e-66	-	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Thioredoxin
HAPAPPHC_01758	6.58e-74	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HAPAPPHC_01759	3.6e-196	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HAPAPPHC_01760	0.0	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
HAPAPPHC_01761	1.5e-29	-	-	-	L	-	-	-	Integrase core domain protein
HAPAPPHC_01762	4.21e-66	-	-	-	L	-	-	-	Integrase core domain protein
HAPAPPHC_01763	1.17e-33	-	-	-	L	-	-	-	transposase activity
HAPAPPHC_01765	0.0	-	-	-	M	-	-	-	Outer membrane protein, OMP85 family
HAPAPPHC_01766	9.79e-183	aviRb	-	-	J	ko:K03437	-	ko00000,ko03016	RNA methyltransferase
HAPAPPHC_01768	7e-179	-	-	-	S	-	-	-	Domain of unknown function (DUF4296)
HAPAPPHC_01769	9.31e-138	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HAPAPPHC_01770	4.17e-80	yocK	-	-	T	-	-	-	Molecular chaperone DnaK
HAPAPPHC_01771	2.77e-72	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HAPAPPHC_01772	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HAPAPPHC_01773	0.0	aglC	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Melibiase
HAPAPPHC_01774	2.61e-254	-	-	-	S	-	-	-	Protein of unknown function (DUF3810)
HAPAPPHC_01775	2.15e-95	-	-	-	S	-	-	-	Peptidase M15
HAPAPPHC_01776	5.22e-37	-	-	-	-	-	-	-	-
HAPAPPHC_01777	8.5e-100	-	-	-	L	-	-	-	DNA-binding protein
HAPAPPHC_01779	1.79e-18	-	-	-	L	-	-	-	Transposase IS66 family
HAPAPPHC_01781	3.19e-302	ugd	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HAPAPPHC_01782	0.0	-	-	-	S	-	-	-	Polysaccharide biosynthesis protein
HAPAPPHC_01783	5.87e-191	-	-	-	M	-	-	-	TupA-like ATPgrasp
HAPAPPHC_01784	1.83e-22	-	-	-	M	-	-	-	TupA-like ATPgrasp
HAPAPPHC_01785	4.83e-294	-	-	-	M	-	-	-	-O-antigen
HAPAPPHC_01786	3.23e-270	-	-	-	M	-	-	-	Glycosyl transferases group 1
HAPAPPHC_01787	7.28e-294	-	-	-	M	ko:K07282	-	ko00000	Bacterial capsule synthesis protein PGA_cap
HAPAPPHC_01788	4.11e-293	-	-	-	M	ko:K07282	-	ko00000	Bacterial capsule synthesis protein PGA_cap
HAPAPPHC_01789	4.75e-245	-	-	-	S	-	-	-	Sugar-transfer associated ATP-grasp
HAPAPPHC_01790	1.57e-258	-	1.1.1.169, 1.5.1.28	-	H	ko:K00077,ko:K04940	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	2-dehydropantoate 2-reductase activity
HAPAPPHC_01791	3.78e-273	-	-	-	S	-	-	-	Sugar-transfer associated ATP-grasp
HAPAPPHC_01792	7.5e-107	-	6.3.5.5	-	S	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	ATP-grasp domain
HAPAPPHC_01793	8.46e-95	-	6.3.5.5	-	S	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	ATP-grasp domain
HAPAPPHC_01794	2.49e-229	-	4.4.1.15	-	E	ko:K05396	ko00270,map00270	ko00000,ko00001,ko01000	Pyridoxal-phosphate dependent enzyme
HAPAPPHC_01795	9.48e-125	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HAPAPPHC_01796	9.05e-145	-	-	-	M	-	-	-	Bacterial sugar transferase
HAPAPPHC_01797	0.0	-	-	-	E	-	-	-	Belongs to the DegT DnrJ EryC1 family
HAPAPPHC_01798	0.0	ptk_3	-	-	DM	-	-	-	Chain length determinant protein
HAPAPPHC_01799	5.48e-169	-	-	-	M	ko:K01991	ko02026,map02026	ko00000,ko00001,ko02000	Polysaccharide biosynthesis/export protein
HAPAPPHC_01800	2.49e-100	-	-	-	S	-	-	-	phosphatase activity
HAPAPPHC_01801	0.0	wbpM	-	-	GM	-	-	-	Polysaccharide biosynthesis protein
HAPAPPHC_01802	8.59e-107	-	-	-	-	-	-	-	-
HAPAPPHC_01803	6.14e-155	-	-	-	K	-	-	-	Participates in transcription elongation, termination and antitermination
HAPAPPHC_01804	4.6e-220	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HAPAPPHC_01806	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HAPAPPHC_01807	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	Pfam:SusD
HAPAPPHC_01808	0.0	-	-	-	S	-	-	-	MlrC C-terminus
HAPAPPHC_01809	0.0	metH	2.1.1.13	-	E	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	B12 binding domain
HAPAPPHC_01810	8.27e-223	-	-	-	P	-	-	-	Nucleoside recognition
HAPAPPHC_01811	1.7e-101	smpB	-	-	O	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HAPAPPHC_01812	3.49e-96	-	-	-	S	-	-	-	Protein of unknown function (DUF1282)
HAPAPPHC_01813	1.77e-09	-	-	-	S	-	-	-	Protein of unknown function (DUF1282)
HAPAPPHC_01817	1.82e-294	-	-	-	S	-	-	-	Outer membrane protein beta-barrel domain
HAPAPPHC_01818	1.24e-97	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HAPAPPHC_01819	3.18e-77	-	-	-	P	ko:K08364	-	ko00000,ko02000	Heavy-metal-associated domain
HAPAPPHC_01820	0.0	-	-	-	P	-	-	-	CarboxypepD_reg-like domain
HAPAPPHC_01821	3.27e-96	-	-	-	-	-	-	-	-
HAPAPPHC_01822	0.0	yngK	-	-	S	-	-	-	Glycosyl hydrolase-like 10
HAPAPPHC_01823	1.55e-176	-	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
HAPAPPHC_01824	1.97e-229	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HAPAPPHC_01825	2.49e-156	lolA	-	-	M	ko:K03634	-	ko00000	Outer membrane lipoprotein carrier protein LolA
HAPAPPHC_01826	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	cell division protein FtsK
HAPAPPHC_01827	2.14e-32	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	cell division protein FtsK
HAPAPPHC_01828	0.0	yccM	-	-	C	-	-	-	4Fe-4S binding domain
HAPAPPHC_01829	8.32e-215	-	-	-	S	ko:K07079	-	ko00000	Aldo/keto reductase family
HAPAPPHC_01830	4.27e-107	-	-	-	S	ko:K07079	-	ko00000	Aldo/keto reductase family
HAPAPPHC_01831	2.04e-123	-	-	-	S	-	-	-	Domain of unknown function (DUF5063)
HAPAPPHC_01832	3.48e-134	rnd	-	-	L	-	-	-	3'-5' exonuclease
HAPAPPHC_01833	2.28e-292	rlmI	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	SAM-dependent methyltransferase
HAPAPPHC_01834	0.0	-	-	-	M	ko:K21572	-	ko00000,ko02000	SusD family
HAPAPPHC_01835	0.0	-	-	-	P	-	-	-	TonB dependent receptor
HAPAPPHC_01836	3.22e-217	mdh	1.1.1.37	-	C	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible oxidation of malate to oxaloacetate
HAPAPPHC_01838	2.5e-160	lpxA2	2.3.1.129	-	M	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	ko00000,ko00001,ko00002,ko01000,ko01005	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HAPAPPHC_01839	1.18e-308	-	-	-	MU	-	-	-	Efflux transporter, outer membrane factor
HAPAPPHC_01840	0.0	mexF	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HAPAPPHC_01841	1.49e-272	mtrC	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HAPAPPHC_01842	3.97e-136	-	-	-	-	-	-	-	-
HAPAPPHC_01843	1.62e-253	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HAPAPPHC_01844	7.44e-190	uxuB	-	-	IQ	-	-	-	KR domain
HAPAPPHC_01845	4.58e-291	uxuA	4.2.1.8	-	G	ko:K01686	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of D-mannonate
HAPAPPHC_01846	1.79e-274	-	-	-	G	-	-	-	Tripartite ATP-independent periplasmic transporter, DctM component
HAPAPPHC_01847	9.72e-98	-	-	-	G	-	-	-	Tripartite ATP-independent periplasmic transporters, DctQ component
HAPAPPHC_01848	3.09e-104	-	-	-	G	-	-	-	Bacterial extracellular solute-binding protein, family 7
HAPAPPHC_01849	2.9e-119	-	-	-	G	-	-	-	Bacterial extracellular solute-binding protein, family 7
HAPAPPHC_01850	7.21e-62	-	-	-	K	-	-	-	addiction module antidote protein HigA
HAPAPPHC_01851	6.96e-201	nlpD_2	-	-	M	-	-	-	Peptidase family M23
HAPAPPHC_01855	0.0	-	-	-	O	-	-	-	ADP-ribosylglycohydrolase
HAPAPPHC_01858	0.0	-	3.1.21.5	-	KL	ko:K01156	-	ko00000,ko01000,ko02048	Type III restriction enzyme, res subunit
HAPAPPHC_01859	0.0	-	2.1.1.72	-	L	ko:K00571,ko:K07316	-	ko00000,ko01000,ko02048	COG2189 Adenine specific DNA methylase Mod
HAPAPPHC_01861	2.54e-77	-	-	-	S	-	-	-	Protein of unknown function DUF86
HAPAPPHC_01862	1.86e-63	-	-	-	S	ko:K07075	-	ko00000	Nucleotidyltransferase domain
HAPAPPHC_01863	2.03e-212	-	-	-	-	-	-	-	-
HAPAPPHC_01864	7.78e-45	-	-	-	K	-	-	-	Helix-turn-helix domain
HAPAPPHC_01866	4.67e-246	-	-	-	L	-	-	-	Arm DNA-binding domain
HAPAPPHC_01868	0.0	bglX	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Fibronectin type III-like domain
HAPAPPHC_01869	3.4e-229	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HAPAPPHC_01873	2.8e-224	cpdB	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01119,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HAPAPPHC_01874	5.49e-177	cpdB	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01119,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HAPAPPHC_01875	0.0	-	-	-	G	-	-	-	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HAPAPPHC_01876	6.03e-176	-	-	-	C	-	-	-	4Fe-4S binding domain
HAPAPPHC_01877	1.21e-119	-	-	-	CO	-	-	-	SCO1/SenC
HAPAPPHC_01878	1.66e-132	iorB	1.2.7.8	-	C	ko:K00180	-	br01601,ko00000,ko01000	Indolepyruvate
HAPAPPHC_01879	0.0	iorA	1.2.7.8	-	C	ko:K00179	-	br01601,ko00000,ko01000	Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates
HAPAPPHC_01880	2.24e-254	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HAPAPPHC_01882	2.91e-132	-	-	-	L	-	-	-	Resolvase, N terminal domain
HAPAPPHC_01883	0.0	-	-	-	C	ko:K09181	-	ko00000	CoA ligase
HAPAPPHC_01884	2.95e-161	hypB	-	-	KO	ko:K04652	-	ko00000,ko03110	CobW/HypB/UreG, nucleotide-binding domain
HAPAPPHC_01885	4.71e-74	hypA	-	-	S	ko:K04651	-	ko00000,ko03110	Probably plays a role in a hydrogenase nickel cofactor insertion step
HAPAPPHC_01886	0.0	-	-	-	O	ko:K04656	-	ko00000	Acylphosphatase
HAPAPPHC_01887	6.13e-48	-	-	-	O	ko:K04653	-	ko00000	HupF/HypC family
HAPAPPHC_01888	9.52e-265	-	-	-	O	ko:K04654	-	ko00000	Hydrogenase formation hypA family
HAPAPPHC_01889	1.18e-228	-	-	-	O	ko:K04655	-	ko00000	AIR synthase related protein, N-terminal domain
HAPAPPHC_01890	7.64e-274	-	1.12.99.6	-	C	ko:K06282	ko00633,ko01120,map00633,map01120	ko00000,ko00001,ko01000	NiFe/NiFeSe hydrogenase small subunit C-terminal
HAPAPPHC_01891	0.0	-	1.12.99.6	-	C	ko:K06281	ko00633,ko01120,map00633,map01120	ko00000,ko00001,ko01000	Nickel-dependent hydrogenase
HAPAPPHC_01892	1.57e-42	-	1.12.99.6	-	C	ko:K06281	ko00633,ko01120,map00633,map01120	ko00000,ko00001,ko01000	Nickel-dependent hydrogenase
HAPAPPHC_01893	4.66e-176	-	-	-	C	ko:K03620	ko02020,map02020	ko00000,ko00001	Domain of unknown function (DUF4405)
HAPAPPHC_01894	4.45e-109	-	-	-	C	ko:K03605	-	ko00000,ko01000,ko01002	Hydrogenase maturation protease
HAPAPPHC_01895	1.02e-179	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Major intrinsic protein
HAPAPPHC_01896	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HAPAPPHC_01897	0.0	glpA	1.1.5.3	-	C	ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	C-terminal domain of alpha-glycerophosphate oxidase
HAPAPPHC_01898	8.71e-52	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
HAPAPPHC_01899	2.58e-147	-	-	-	L	-	-	-	COG COG2801 Transposase and inactivated derivatives
HAPAPPHC_01900	0.0	mrcA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Penicillin-binding Protein
HAPAPPHC_01901	1.7e-238	-	-	-	S	-	-	-	Belongs to the UPF0324 family
HAPAPPHC_01902	2.16e-206	cysL	-	-	K	-	-	-	LysR substrate binding domain
HAPAPPHC_01903	6.29e-221	-	-	-	CO	-	-	-	Domain of unknown function (DUF5106)
HAPAPPHC_01904	1.95e-178	loiP	-	-	O	ko:K07387	-	ko00000,ko01000,ko01002	Peptidase family M48
HAPAPPHC_01905	3.93e-138	-	-	-	T	-	-	-	Histidine kinase-like ATPases
HAPAPPHC_01906	2.69e-141	-	-	-	S	ko:K08999	-	ko00000	Bifunctional nuclease
HAPAPPHC_01907	1.66e-305	nupC	-	-	F	ko:K03317	-	ko00000	Na+ dependent nucleoside transporter C-terminus
HAPAPPHC_01908	3.17e-172	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HAPAPPHC_01909	3.44e-187	-	-	-	G	-	-	-	Domain of Unknown Function (DUF1080)
HAPAPPHC_01910	0.0	-	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	GMP synthase C terminal domain
HAPAPPHC_01911	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
HAPAPPHC_01912	1.74e-155	-	-	-	S	-	-	-	Fic/DOC family
HAPAPPHC_01913	3.2e-145	-	-	-	S	-	-	-	Fic/DOC family
HAPAPPHC_01916	7.28e-147	-	-	-	S	-	-	-	Protein of unknown function (DUF3987)
HAPAPPHC_01917	2.75e-177	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
HAPAPPHC_01918	6.14e-78	-	-	-	S	-	-	-	Bacterial mobilisation protein (MobC)
HAPAPPHC_01919	3.98e-187	-	-	-	U	-	-	-	Mobilization protein
HAPAPPHC_01920	8.98e-124	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HAPAPPHC_01921	7.11e-60	-	-	-	S	-	-	-	Helix-turn-helix domain
HAPAPPHC_01922	3.29e-90	-	-	-	-	-	-	-	-
HAPAPPHC_01923	6.48e-50	XK26_02160	-	-	K	-	-	-	Pyridoxamine 5'-phosphate oxidase
HAPAPPHC_01924	8.06e-161	-	-	-	-	-	-	-	-
HAPAPPHC_01925	1.13e-139	-	-	-	S	ko:K07118	-	ko00000	NmrA-like family
HAPAPPHC_01926	4.16e-43	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HAPAPPHC_01927	2.04e-20	-	-	-	L	-	-	-	Arm DNA-binding domain
HAPAPPHC_01930	1.02e-84	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HAPAPPHC_01931	2.63e-288	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HAPAPPHC_01932	0.0	-	-	-	M	-	-	-	AsmA-like C-terminal region
HAPAPPHC_01933	0.0	cap5D	-	-	GM	-	-	-	Polysaccharide biosynthesis protein
HAPAPPHC_01934	4.59e-284	pglE	-	-	E	-	-	-	DegT/DnrJ/EryC1/StrS aminotransferase family
HAPAPPHC_01935	4.22e-140	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	KR domain
HAPAPPHC_01936	1.99e-197	-	-	-	IQ	-	-	-	AMP-binding enzyme C-terminal domain
HAPAPPHC_01937	6.68e-30	-	-	-	IQ	ko:K02078	-	ko00000,ko00001	Phosphopantetheine attachment site
HAPAPPHC_01938	2.64e-38	-	-	-	M	-	-	-	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HAPAPPHC_01939	8.89e-121	pglC	2.7.8.36	-	M	ko:K15915	-	ko00000,ko01000	Bacterial sugar transferase
HAPAPPHC_01940	0.000427	-	-	-	-	-	-	-	-
HAPAPPHC_01941	2.35e-184	wbuB	-	-	M	-	-	-	Glycosyl transferases group 1
HAPAPPHC_01942	4.19e-255	-	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HAPAPPHC_01943	1.5e-152	-	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HAPAPPHC_01944	1.32e-13	-	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HAPAPPHC_01945	3.94e-250	-	5.1.3.2	-	M	ko:K17716	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Polysaccharide biosynthesis protein C-terminal
HAPAPPHC_01946	2.77e-158	-	-	-	-	-	-	-	-
HAPAPPHC_01947	3.43e-156	fadD	-	-	IQ	-	-	-	AMP-binding enzyme
HAPAPPHC_01948	1.15e-19	-	-	-	IQ	-	-	-	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HAPAPPHC_01950	1.64e-57	-	-	-	S	-	-	-	Glycosyltransferase like family 2
HAPAPPHC_01952	9.4e-93	-	-	-	M	-	-	-	Domain of unknown function (DUF4422)
HAPAPPHC_01953	4.13e-216	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
HAPAPPHC_01954	2.77e-64	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HAPAPPHC_01955	2.16e-195	-	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 9.97
HAPAPPHC_01956	2.22e-160	-	-	-	S	-	-	-	Polysaccharide biosynthesis protein
HAPAPPHC_01957	1.36e-42	-	-	-	S	-	-	-	Transposase IS66 family
HAPAPPHC_01959	1.47e-103	-	-	-	L	-	-	-	Integrase core domain protein
HAPAPPHC_01961	1.04e-108	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.96
HAPAPPHC_01962	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HAPAPPHC_01963	1.78e-207	natA	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HAPAPPHC_01964	4.97e-307	natB	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter permease
HAPAPPHC_01967	2.58e-82	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HAPAPPHC_01968	8.74e-46	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HAPAPPHC_01969	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HAPAPPHC_01970	5.73e-202	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
HAPAPPHC_01971	1.07e-162	porT	-	-	S	-	-	-	PorT protein
HAPAPPHC_01972	2.13e-21	-	-	-	C	-	-	-	4Fe-4S binding domain
HAPAPPHC_01973	6.6e-83	-	-	-	S	-	-	-	Protein of unknown function (DUF3276)
HAPAPPHC_01974	1.26e-216	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HAPAPPHC_01975	3.22e-51	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit YajC
HAPAPPHC_01976	9.49e-238	-	-	-	S	-	-	-	YbbR-like protein
HAPAPPHC_01977	7.88e-131	coaE	2.7.1.24	-	H	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HAPAPPHC_01978	5.81e-96	-	-	-	S	-	-	-	COG NOG14473 non supervised orthologous group
HAPAPPHC_01979	9.53e-191	-	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	glucokinase
HAPAPPHC_01980	1.15e-181	-	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HAPAPPHC_01981	0.0	-	2.3.1.54, 4.1.1.83	-	C	ko:K00656,ko:K18427	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
HAPAPPHC_01982	1.42e-218	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	4Fe-4S single cluster domain
HAPAPPHC_01983	2.1e-141	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HAPAPPHC_01984	1.23e-222	-	-	-	K	-	-	-	AraC-like ligand binding domain
HAPAPPHC_01985	8.77e-192	-	-	-	G	-	-	-	Domain of Unknown Function (DUF1080)
HAPAPPHC_01986	8.87e-291	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HAPAPPHC_01987	3e-75	-	-	-	-	-	-	-	-
HAPAPPHC_01988	1.17e-38	-	-	-	-	-	-	-	-
HAPAPPHC_01989	4.62e-48	-	-	-	S	-	-	-	COG NOG33922 non supervised orthologous group
HAPAPPHC_01990	1.29e-96	-	-	-	S	-	-	-	PcfK-like protein
HAPAPPHC_01991	7.9e-316	-	-	-	S	-	-	-	PcfJ-like protein
HAPAPPHC_01992	5.13e-55	-	-	-	-	-	-	-	-
HAPAPPHC_01993	1.4e-48	-	-	-	S	-	-	-	Domain of unknown function, B. Theta Gene description (DUF3873)
HAPAPPHC_01994	7.13e-56	-	-	-	-	-	-	-	-
HAPAPPHC_01995	2.91e-62	-	-	-	-	-	-	-	-
HAPAPPHC_01996	3.81e-126	-	-	-	-	-	-	-	-
HAPAPPHC_01997	5.93e-124	-	3.2.1.17	-	S	ko:K01185	-	ko00000,ko01000	lysozyme
HAPAPPHC_01998	5.33e-119	-	-	-	S	-	-	-	Domain of unknown function, B. Theta Gene description (DUF3872)
HAPAPPHC_01999	8.92e-217	-	-	-	L	-	-	-	CHC2 zinc finger
HAPAPPHC_02000	1.95e-139	-	-	-	S	-	-	-	Conjugal transfer protein TraO
HAPAPPHC_02001	3.31e-238	-	-	-	U	-	-	-	Domain of unknown function (DUF4138)
HAPAPPHC_02002	7.2e-215	traM	-	-	S	-	-	-	Conjugative transposon TraM protein
HAPAPPHC_02003	2.01e-72	traM	-	-	S	-	-	-	Conjugative transposon TraM protein
HAPAPPHC_02004	2.79e-69	-	-	-	S	-	-	-	Protein of unknown function (DUF3989)
HAPAPPHC_02005	4.4e-87	traK	-	-	U	-	-	-	Conjugative transposon TraK protein
HAPAPPHC_02006	5.16e-41	traK	-	-	U	-	-	-	Conjugative transposon TraK protein
HAPAPPHC_02007	5.81e-226	traJ	-	-	S	-	-	-	Conjugative transposon TraJ protein
HAPAPPHC_02008	3.94e-116	-	-	-	U	-	-	-	Domain of unknown function (DUF4141)
HAPAPPHC_02009	6.14e-87	-	-	-	S	-	-	-	COG NOG30362 non supervised orthologous group
HAPAPPHC_02010	0.0	-	-	-	U	-	-	-	conjugation system ATPase
HAPAPPHC_02011	8.08e-103	-	-	-	U	-	-	-	conjugation system ATPase
HAPAPPHC_02012	6.33e-72	-	-	-	S	-	-	-	COG NOG30259 non supervised orthologous group
HAPAPPHC_02013	0.000348	traG	-	-	U	-	-	-	Conjugation system ATPase, TraG family
HAPAPPHC_02014	0.0	-	2.7.7.49	-	H	ko:K00986	-	ko00000,ko01000	Group II intron, maturase-specific domain
HAPAPPHC_02015	2.21e-39	-	-	-	S	-	-	-	Domain of unknown function (DUF4134)
HAPAPPHC_02016	8.94e-128	-	-	-	S	-	-	-	Conjugal transfer protein traD
HAPAPPHC_02017	1.65e-117	-	-	-	S	-	-	-	Conjugal transfer protein traD
HAPAPPHC_02018	4.45e-39	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HAPAPPHC_02019	0.0	-	2.7.7.49	-	H	ko:K00986	-	ko00000,ko01000	Group II intron, maturase-specific domain
HAPAPPHC_02020	1.97e-13	-	-	-	S	-	-	-	Conjugative transposon protein TraE
HAPAPPHC_02021	5.21e-71	-	-	-	S	-	-	-	COG NOG30259 non supervised orthologous group
HAPAPPHC_02022	0.0	-	-	-	U	-	-	-	Conjugation system ATPase, TraG family
HAPAPPHC_02023	3.56e-86	-	-	-	S	-	-	-	COG NOG30362 non supervised orthologous group
HAPAPPHC_02024	2.65e-114	-	-	-	U	-	-	-	Domain of unknown function (DUF4141)
HAPAPPHC_02025	1.01e-226	traJ	-	-	S	-	-	-	Conjugative transposon TraJ protein
HAPAPPHC_02026	4.35e-144	traK	-	-	U	-	-	-	Conjugative transposon TraK protein
HAPAPPHC_02027	4.46e-66	-	-	-	S	-	-	-	Protein of unknown function (DUF3989)
HAPAPPHC_02028	5.41e-310	traM	-	-	S	-	-	-	Conjugative transposon TraM protein
HAPAPPHC_02029	3.1e-52	-	-	-	U	-	-	-	Conjugative transposon TraN protein
HAPAPPHC_02030	7.13e-146	-	-	-	U	-	-	-	Conjugative transposon TraN protein
HAPAPPHC_02031	1.01e-118	-	-	-	S	-	-	-	COG NOG19079 non supervised orthologous group
HAPAPPHC_02032	4.32e-196	-	-	-	L	-	-	-	CHC2 zinc finger domain protein
HAPAPPHC_02033	1.79e-117	-	-	-	S	-	-	-	Domain of unknown function, B. Theta Gene description (DUF3872)
HAPAPPHC_02034	3.43e-123	-	3.2.1.17	-	S	ko:K01185	-	ko00000,ko01000	lysozyme
HAPAPPHC_02036	1.47e-150	-	-	-	H	-	-	-	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HAPAPPHC_02037	1e-63	-	-	-	-	-	-	-	-
HAPAPPHC_02038	1.97e-53	-	-	-	-	-	-	-	-
HAPAPPHC_02039	2.33e-47	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HAPAPPHC_02040	8.86e-56	-	-	-	-	-	-	-	-
HAPAPPHC_02041	7.34e-308	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HAPAPPHC_02042	1.55e-94	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HAPAPPHC_02043	3.11e-34	-	-	-	-	-	-	-	-
HAPAPPHC_02044	1.05e-75	-	-	-	-	-	-	-	-
HAPAPPHC_02045	1.53e-31	-	-	-	-	-	-	-	-
HAPAPPHC_02046	2.21e-228	phoH	-	-	T	ko:K06217	-	ko00000	Phosphate starvation protein PhoH
HAPAPPHC_02047	4.48e-230	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis
HAPAPPHC_02048	1.9e-176	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HAPAPPHC_02049	3.42e-179	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Shikimate
HAPAPPHC_02050	1.58e-145	sfp	-	-	H	-	-	-	Belongs to the P-Pant transferase superfamily
HAPAPPHC_02051	1.8e-136	gldD	-	-	S	-	-	-	Gliding motility-associated lipoprotein GldD
HAPAPPHC_02052	1.62e-309	gldE	-	-	S	-	-	-	gliding motility-associated protein GldE
HAPAPPHC_02053	7.85e-117	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
HAPAPPHC_02054	1.2e-90	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HAPAPPHC_02055	5.24e-44	-	-	-	L	-	-	-	Phage integrase SAM-like domain
HAPAPPHC_02056	4.68e-59	-	-	-	-	-	-	-	-
HAPAPPHC_02060	8.08e-100	-	-	-	JKL	-	-	-	Belongs to the DEAD box helicase family
HAPAPPHC_02063	1.89e-55	-	-	-	S	-	-	-	phosphatase homologous to the C-terminal domain of histone macroH2A1
HAPAPPHC_02064	5.7e-09	-	-	-	S	-	-	-	HNH endonuclease
HAPAPPHC_02067	8.85e-50	-	-	-	L	-	-	-	Phage terminase, small subunit
HAPAPPHC_02068	0.0	-	-	-	S	-	-	-	Phage Terminase
HAPAPPHC_02069	2.74e-168	-	-	-	S	-	-	-	Phage portal protein
HAPAPPHC_02071	3.1e-10	-	-	-	-	-	-	-	-
HAPAPPHC_02072	2.34e-69	-	-	-	S	ko:K06904	-	ko00000	Caudovirus prohead serine protease
HAPAPPHC_02073	2.08e-204	-	-	-	S	-	-	-	Phage capsid family
HAPAPPHC_02074	1.24e-44	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HAPAPPHC_02075	5.39e-32	-	-	-	S	-	-	-	Phage head-tail joining protein
HAPAPPHC_02076	6.32e-51	-	-	-	-	-	-	-	-
HAPAPPHC_02077	1.47e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF3168)
HAPAPPHC_02078	1.32e-45	-	-	-	S	-	-	-	Phage tail tube protein
HAPAPPHC_02080	2.17e-28	-	-	-	-	-	-	-	-
HAPAPPHC_02082	2.93e-102	-	-	-	D	-	-	-	domain protein
HAPAPPHC_02083	5.77e-116	-	-	-	-	-	-	-	-
HAPAPPHC_02084	3.3e-62	-	-	-	U	-	-	-	Chaperone of endosialidase
HAPAPPHC_02091	2.62e-15	-	-	-	N	-	-	-	HicA toxin of bacterial toxin-antitoxin,
HAPAPPHC_02092	3.88e-38	-	-	-	S	-	-	-	PFAM Uncharacterised protein family UPF0150
HAPAPPHC_02093	1.42e-265	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific adenine glycosylase
HAPAPPHC_02094	8.94e-56	hupA	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Belongs to the bacterial histone-like protein family
HAPAPPHC_02096	0.0	rng	-	-	J	ko:K08301	-	ko00000,ko01000,ko03009,ko03019	ribonuclease G
HAPAPPHC_02097	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HAPAPPHC_02098	0.0	-	-	-	T	-	-	-	Histidine kinase-like ATPases
HAPAPPHC_02099	0.0	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
HAPAPPHC_02100	9.93e-305	-	-	-	EGP	ko:K08218	ko01501,map01501	ko00000,ko00001,ko00002,ko02000	BT1 family
HAPAPPHC_02101	6.2e-147	ramA_1	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Hydrolase, carbon-nitrogen family
HAPAPPHC_02102	2.96e-129	-	-	-	I	-	-	-	Acyltransferase
HAPAPPHC_02103	5.36e-62	-	-	-	S	-	-	-	COG NOG23371 non supervised orthologous group
HAPAPPHC_02104	0.0	-	2.4.1.11	GT3	G	ko:K00693	ko00500,ko01100,ko04151,ko04152,ko04910,ko04922,ko04931,map00500,map01100,map04151,map04152,map04910,map04922,map04931	ko00000,ko00001,ko01000,ko01003	starch synthase
HAPAPPHC_02105	0.0	glgP	2.4.1.1, 2.4.1.11, 2.4.1.8	GH65,GT3,GT35	G	ko:K00688,ko:K00691,ko:K16153	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000,ko01003	alpha-glucan phosphorylase
HAPAPPHC_02106	0.0	-	-	-	I	ko:K06076	-	ko00000,ko02000	Psort location OuterMembrane, score 9.52
HAPAPPHC_02107	7.62e-293	-	-	-	P	ko:K07214	-	ko00000	Putative esterase
HAPAPPHC_02108	1.07e-209	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HAPAPPHC_02109	3.05e-109	-	-	-	S	-	-	-	Calcium/calmodulin dependent protein kinase II association domain
HAPAPPHC_02110	6.1e-230	-	-	-	S	-	-	-	Fimbrillin-like
HAPAPPHC_02111	6.91e-198	-	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Formamidopyrimidine-DNA glycosylase H2TH domain
HAPAPPHC_02114	6.26e-143	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HAPAPPHC_02115	2.13e-169	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidine biosynthesis protein
HAPAPPHC_02116	3.83e-178	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HAPAPPHC_02117	1.65e-139	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidine biosynthesis bifunctional protein hisIE
HAPAPPHC_02118	1.38e-159	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	ABC transporter, ATP-binding protein
HAPAPPHC_02119	3.98e-313	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HAPAPPHC_02120	2.61e-280	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HAPAPPHC_02121	4.98e-272	-	-	-	M	-	-	-	Glycosyltransferase family 2
HAPAPPHC_02122	7.85e-122	vsr	-	-	L	ko:K07458	-	ko00000,ko01000,ko03400	May nick specific sequences that contain T G mispairs resulting from m5C-deamination
HAPAPPHC_02123	1.73e-288	lolE_1	-	-	M	ko:K09808	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HAPAPPHC_02124	6.8e-292	aspC	2.6.1.1, 2.6.1.2, 2.6.1.66	-	E	ko:K00812,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aspartate aminotransferase
HAPAPPHC_02125	0.0	-	-	-	S	-	-	-	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HAPAPPHC_02126	3.07e-208	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HAPAPPHC_02127	1.23e-83	-	-	-	S	-	-	-	COG NOG30654 non supervised orthologous group
HAPAPPHC_02128	1.41e-20	-	-	-	S	-	-	-	COG NOG30654 non supervised orthologous group
HAPAPPHC_02130	3.16e-80	-	-	-	S	-	-	-	COG NOG30654 non supervised orthologous group
HAPAPPHC_02133	6.18e-105	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HAPAPPHC_02134	5.08e-108	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HAPAPPHC_02135	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter
HAPAPPHC_02136	3.88e-167	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HAPAPPHC_02137	2.14e-172	-	-	-	S	-	-	-	Uncharacterised ArCR, COG2043
HAPAPPHC_02138	1.87e-72	ogt	2.1.1.63	-	L	ko:K00567,ko:K07443	-	ko00000,ko01000,ko03400	6-O-methylguanine DNA methyltransferase, DNA binding domain
HAPAPPHC_02139	1.12e-78	-	-	-	-	-	-	-	-
HAPAPPHC_02140	7.16e-10	-	-	-	S	-	-	-	Protein of unknown function, DUF417
HAPAPPHC_02141	1.31e-267	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HAPAPPHC_02142	2.69e-191	-	-	-	K	-	-	-	Helix-turn-helix domain
HAPAPPHC_02143	2.51e-73	-	-	-	K	-	-	-	Peptidase S24-like
HAPAPPHC_02145	1.24e-39	-	3.2.1.17	-	G	ko:K01185	-	ko00000,ko01000	lysozyme
HAPAPPHC_02147	0.0	-	-	-	S	-	-	-	Phage minor structural protein
HAPAPPHC_02150	6.4e-15	-	-	-	-	-	-	-	-
HAPAPPHC_02156	4.94e-16	-	-	-	-	-	-	-	-
HAPAPPHC_02158	1.56e-20	-	-	-	D	-	-	-	nuclear chromosome segregation
HAPAPPHC_02159	0.0	-	-	-	S	-	-	-	regulation of response to stimulus
HAPAPPHC_02160	1.5e-166	-	-	-	K	-	-	-	stress protein (general stress protein 26)
HAPAPPHC_02161	3.98e-132	-	-	-	EGP	ko:K08224	-	ko00000,ko02000	Major Facilitator
HAPAPPHC_02162	6.02e-110	-	-	-	K	ko:K11921	-	ko00000,ko03000	LysR substrate binding domain
HAPAPPHC_02163	1.91e-128	-	-	-	K	ko:K13652	-	ko00000,ko03000	methylphosphotriester-DNA alkyltransferase (AraC XylS family)
HAPAPPHC_02164	5.82e-103	-	-	-	S	-	-	-	Pentapeptide repeats (8 copies)
HAPAPPHC_02165	4.03e-57	-	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
HAPAPPHC_02166	2.49e-182	-	-	-	-	-	-	-	-
HAPAPPHC_02167	0.0	-	-	-	-	-	-	-	-
HAPAPPHC_02168	4.73e-241	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
HAPAPPHC_02169	0.0	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HAPAPPHC_02170	7.21e-192	-	-	-	S	-	-	-	Outer membrane protein beta-barrel domain
HAPAPPHC_02171	7.28e-267	-	-	-	S	-	-	-	Putative carbohydrate metabolism domain
HAPAPPHC_02172	2.38e-260	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HAPAPPHC_02173	0.0	-	-	-	H	-	-	-	NAD metabolism ATPase kinase
HAPAPPHC_02174	0.0	relA	2.7.6.5, 3.1.7.2	-	KT	ko:K00951,ko:K01139	ko00230,map00230	ko00000,ko00001,ko01000,ko03009	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HAPAPPHC_02175	0.0	cca	2.7.7.19, 2.7.7.72	-	J	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	tRNA nucleotidyltransferase
HAPAPPHC_02176	1.45e-194	-	-	-	-	-	-	-	-
HAPAPPHC_02177	1.56e-06	-	-	-	-	-	-	-	-
HAPAPPHC_02179	1.37e-186	-	-	-	M	ko:K03442	-	ko00000,ko02000	mechanosensitive ion channel
HAPAPPHC_02180	2.27e-109	-	-	-	S	-	-	-	Tetratricopeptide repeat
HAPAPPHC_02181	4.69e-262	leuB	1.1.1.85	-	C	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HAPAPPHC_02182	2.87e-106	mgsA	4.2.3.3	-	G	ko:K01734	ko00640,ko01120,map00640,map01120	ko00000,ko00001,ko01000	methylglyoxal synthase
HAPAPPHC_02183	0.0	leuA_1	2.3.1.182	-	E	ko:K09011	ko00290,ko00660,ko01100,ko01210,ko01230,map00290,map00660,map01100,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the alpha-IPM synthase homocitrate synthase family
HAPAPPHC_02184	7.6e-139	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HAPAPPHC_02185	0.0	leuC	4.2.1.33, 4.2.1.35	-	H	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HAPAPPHC_02186	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HAPAPPHC_02188	5.51e-288	-	-	-	N	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	domain, Protein
HAPAPPHC_02189	5.61e-102	-	-	-	N	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	domain, Protein
HAPAPPHC_02190	0.0	-	-	-	S	-	-	-	regulation of response to stimulus
HAPAPPHC_02191	6.83e-61	-	-	-	L	-	-	-	DNA-binding protein
HAPAPPHC_02194	2.66e-45	-	-	-	S	-	-	-	ParE toxin of type II toxin-antitoxin system, parDE
HAPAPPHC_02195	8.31e-253	ilvC	1.1.1.86	-	E	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Ketol-acid reductoisomerase
HAPAPPHC_02196	1.51e-179	-	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
HAPAPPHC_02197	2.66e-120	ilvN	2.2.1.6	-	E	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	synthase small subunit
HAPAPPHC_02198	0.0	ilvB	2.2.1.6	-	H	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Acetolactate synthase, large subunit
HAPAPPHC_02199	3.87e-74	ilvD	4.2.1.9	-	EG	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the IlvD Edd family
HAPAPPHC_02200	0.0	ilvD	4.2.1.9	-	EG	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the IlvD Edd family
HAPAPPHC_02202	6.63e-109	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70, region 4
HAPAPPHC_02203	2.28e-248	-	-	-	PT	-	-	-	Domain of unknown function (DUF4974)
HAPAPPHC_02204	0.0	-	-	-	P	-	-	-	TonB dependent receptor
HAPAPPHC_02205	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	SusD family
HAPAPPHC_02206	0.0	-	-	-	P	-	-	-	Domain of unknown function (DUF4976)
HAPAPPHC_02207	0.0	-	3.1.6.1	-	P	ko:K01130	ko00140,ko00600,map00140,map00600	ko00000,ko00001,ko01000	Arylsulfatase
HAPAPPHC_02208	1.32e-294	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase class I and II
HAPAPPHC_02209	1.32e-137	slyD	5.2.1.8	-	O	ko:K03775	-	ko00000,ko01000,ko03110	Peptidyl-prolyl cis-trans isomerase
HAPAPPHC_02210	3.44e-262	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HAPAPPHC_02211	2.08e-66	sugE	-	-	P	ko:K11741	-	ko00000,ko02000	Small Multidrug Resistance protein
HAPAPPHC_02212	1.82e-107	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HAPAPPHC_02213	2.17e-76	-	-	-	S	-	-	-	Domain of unknown function (DUF4783)
HAPAPPHC_02214	7.19e-197	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NadC ModD family
HAPAPPHC_02215	0.0	-	1.2.1.21, 1.2.1.22	-	C	ko:K07248	ko00620,ko00630,ko01120,map00620,map00630,map01120	ko00000,ko00001,ko01000	Aldehyde dehydrogenase family
HAPAPPHC_02216	0.0	dnaX	2.7.7.7	-	H	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HAPAPPHC_02217	4.85e-65	-	-	-	D	-	-	-	Septum formation initiator
HAPAPPHC_02218	6.94e-70	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HAPAPPHC_02219	8.03e-128	-	-	-	M	ko:K06142	-	ko00000	Outer membrane protein (OmpH-like)
HAPAPPHC_02220	5.31e-22	-	-	-	S	-	-	-	COG NOG35566 non supervised orthologous group
HAPAPPHC_02221	0.0	-	-	-	E	ko:K01270	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Catalyzes the hydrolysis of Xaa-His dipeptides
HAPAPPHC_02222	0.0	-	-	-	-	-	-	-	-
HAPAPPHC_02223	2.3e-159	-	-	-	S	-	-	-	Endonuclease exonuclease phosphatase family
HAPAPPHC_02225	2e-157	pdxH	1.4.3.5	-	H	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)
HAPAPPHC_02226	0.0	-	-	-	M	-	-	-	Peptidase family M23
HAPAPPHC_02227	0.0	pgcA	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase
HAPAPPHC_02228	1.18e-108	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HAPAPPHC_02229	1.3e-190	-	-	-	S	-	-	-	ATPase domain predominantly from Archaea
HAPAPPHC_02230	7.87e-105	cypM_1	-	-	H	-	-	-	Methyltransferase domain
HAPAPPHC_02231	8.72e-188	-	-	-	-	-	-	-	-
HAPAPPHC_02232	1.08e-214	lytG	-	-	MNU	-	-	-	N-acetylmuramoyl-L-alanine amidase
HAPAPPHC_02233	1.71e-284	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
HAPAPPHC_02234	4.9e-263	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HAPAPPHC_02235	2.52e-202	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the OMP decarboxylase family. Type 2 subfamily
HAPAPPHC_02236	6.24e-165	lpxD	2.3.1.191	-	M	ko:K02536	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HAPAPPHC_02237	0.0	fabZ	3.5.1.108, 4.2.1.59	-	IM	ko:K16363	ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis
HAPAPPHC_02238	4.16e-125	lpxA	2.3.1.129	-	M	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	ko00000,ko00001,ko00002,ko01000,ko01005	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HAPAPPHC_02239	1.66e-84	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HAPAPPHC_02240	3.64e-36	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HAPAPPHC_02242	7.36e-128	-	-	-	S	-	-	-	Plasmid pRiA4b ORF-3-like protein
HAPAPPHC_02243	3.11e-217	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HAPAPPHC_02244	2.32e-46	-	-	-	S	ko:K09922	-	ko00000	Putative member of DMT superfamily (DUF486)
HAPAPPHC_02245	4.87e-184	ttcA	-	-	H	ko:K14058	-	ko00000,ko03016	Belongs to the TtcA family
HAPAPPHC_02246	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat protein
HAPAPPHC_02247	5.54e-100	-	-	-	O	-	-	-	NfeD-like C-terminal, partner-binding
HAPAPPHC_02248	7.88e-206	-	-	-	S	-	-	-	UPF0365 protein
HAPAPPHC_02249	4.05e-208	udp	2.4.2.3	-	F	ko:K00757	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	phosphorylase
HAPAPPHC_02250	3.02e-162	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
HAPAPPHC_02251	3.81e-172	-	1.5.1.38, 1.5.1.39	-	C	ko:K19285,ko:K19286	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	Nitroreductase family
HAPAPPHC_02252	6.83e-292	-	-	-	S	ko:K07133	-	ko00000	Psort location Cytoplasmic, score 8.96
HAPAPPHC_02253	1.7e-260	-	-	-	C	ko:K07138	-	ko00000	Domain of unknown function (DUF362)
HAPAPPHC_02254	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HAPAPPHC_02255	6.46e-174	-	-	-	L	-	-	-	DNA binding domain, excisionase family
HAPAPPHC_02256	3.46e-264	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HAPAPPHC_02257	7.94e-174	-	-	-	S	-	-	-	COG NOG31621 non supervised orthologous group
HAPAPPHC_02258	1.85e-82	-	-	-	K	-	-	-	COG NOG37763 non supervised orthologous group
HAPAPPHC_02259	9.13e-241	-	-	-	T	-	-	-	COG NOG25714 non supervised orthologous group
HAPAPPHC_02260	1.54e-91	-	-	-	-	-	-	-	-
HAPAPPHC_02261	7.41e-92	-	-	-	-	-	-	-	-
HAPAPPHC_02262	5.58e-136	-	-	-	-	-	-	-	-
HAPAPPHC_02263	2.98e-110	-	-	-	-	-	-	-	-
HAPAPPHC_02264	0.0	-	-	-	K	-	-	-	COG NOG06131 non supervised orthologous group
HAPAPPHC_02265	0.0	-	-	-	K	-	-	-	COG NOG06131 non supervised orthologous group
HAPAPPHC_02266	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HAPAPPHC_02267	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
HAPAPPHC_02268	8.08e-177	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	COG COG0732 Restriction endonuclease S subunits
HAPAPPHC_02269	2.13e-229	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HAPAPPHC_02270	4.99e-150	-	-	-	P	-	-	-	Protein of unknown function (DUF4435)
HAPAPPHC_02271	3.71e-77	-	-	-	L	-	-	-	Type I restriction modification DNA specificity domain protein
HAPAPPHC_02272	1.45e-308	-	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	Psort location Cytoplasmic, score 8.96
HAPAPPHC_02273	0.0	-	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	COG0286 Type I restriction-modification system methyltransferase subunit
HAPAPPHC_02274	0.0	-	-	-	S	ko:K06921	-	ko00000	Archaea bacterial proteins of unknown function
HAPAPPHC_02275	7.47e-61	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
HAPAPPHC_02276	5.9e-97	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HAPAPPHC_02277	1.61e-143	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase superfamily domain
HAPAPPHC_02279	2.25e-26	-	-	-	S	-	-	-	RloB-like protein
HAPAPPHC_02280	7.96e-16	-	-	-	-	-	-	-	-
HAPAPPHC_02281	2.15e-137	-	-	-	S	-	-	-	DJ-1/PfpI family
HAPAPPHC_02282	0.0	-	-	-	S	-	-	-	Domain of unknonw function from B. Theta Gene description (DUF3874)
HAPAPPHC_02283	1.93e-49	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
HAPAPPHC_02284	2.51e-148	-	-	-	L	-	-	-	COG COG2801 Transposase and inactivated derivatives
HAPAPPHC_02285	1.35e-97	-	-	-	-	-	-	-	-
HAPAPPHC_02286	1.24e-202	-	-	-	S	-	-	-	HEPN domain
HAPAPPHC_02287	1.16e-264	yjmD_2	-	-	E	ko:K18369	ko00640,map00640	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent
HAPAPPHC_02288	3.96e-120	-	-	-	C	-	-	-	Flavodoxin
HAPAPPHC_02289	6.83e-133	-	-	-	S	-	-	-	Flavin reductase like domain
HAPAPPHC_02290	2.54e-301	-	-	-	M	ko:K07071	-	ko00000	Domain of unknown function (DUF1731)
HAPAPPHC_02291	2.72e-199	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HAPAPPHC_02292	5.79e-120	-	-	-	J	ko:K03827	-	ko00000,ko01000	Acetyltransferase, gnat family
HAPAPPHC_02293	1.41e-109	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HAPAPPHC_02294	1.49e-80	-	-	-	K	-	-	-	Acetyltransferase, gnat family
HAPAPPHC_02295	1.21e-105	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HAPAPPHC_02296	0.0	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
HAPAPPHC_02297	0.0	rluA	5.4.99.28, 5.4.99.29	-	J	ko:K06177	-	ko00000,ko01000,ko03009,ko03016	RNA pseudouridylate synthase
HAPAPPHC_02298	1.02e-46	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HAPAPPHC_02299	0.0	mepA_7	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HAPAPPHC_02300	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 92
HAPAPPHC_02301	1.03e-59	-	2.3.1.201	-	S	ko:K13018	ko00520,map00520	ko00000,ko00001,ko01000,ko01005	Bacterial transferase hexapeptide repeat
HAPAPPHC_02302	2.01e-40	-	2.3.1.201	-	S	ko:K13018	ko00520,map00520	ko00000,ko00001,ko01000,ko01005	Bacterial transferase hexapeptide repeat
HAPAPPHC_02303	3.41e-168	rsmI_1	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Methyltransferase
HAPAPPHC_02304	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family
HAPAPPHC_02305	8.52e-244	-	-	-	L	-	-	-	Domain of unknown function (DUF4837)
HAPAPPHC_02306	6.05e-53	-	-	-	S	-	-	-	Tetratricopeptide repeat
HAPAPPHC_02307	0.0	ppk	2.7.4.1	-	H	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HAPAPPHC_02308	2.87e-122	-	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
HAPAPPHC_02309	8.07e-259	-	-	-	I	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HAPAPPHC_02310	1.47e-206	lipA	2.8.1.8	-	H	ko:K03644	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HAPAPPHC_02311	0.0	dpp	3.4.14.5	-	EU	ko:K01278	ko04974,map04974	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	Peptidase, S9A B C family, catalytic domain protein
HAPAPPHC_02312	1.82e-158	-	-	-	S	ko:K07139	-	ko00000	radical SAM protein
HAPAPPHC_02313	2.65e-108	-	-	-	S	-	-	-	Domain of unknown function (DUF4251)
HAPAPPHC_02314	2.83e-237	-	-	-	E	-	-	-	Carboxylesterase family
HAPAPPHC_02315	8.96e-68	-	-	-	-	-	-	-	-
HAPAPPHC_02316	0.0	-	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Calcium-translocating P-type ATPase, PMCA-type
HAPAPPHC_02317	1e-143	-	-	-	S	-	-	-	COG NOG23385 non supervised orthologous group
HAPAPPHC_02318	0.0	-	-	-	P	-	-	-	Outer membrane protein beta-barrel family
HAPAPPHC_02319	1.58e-117	-	5.2.1.8	-	O	ko:K01802	-	ko00000,ko01000	Peptidyl-prolyl cis-trans isomerase
HAPAPPHC_02320	0.0	-	3.4.14.5	-	EU	ko:K01278	ko04974,map04974	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	Dipeptidyl peptidase IV (DPP IV) N-terminal region
HAPAPPHC_02321	0.0	-	-	-	M	-	-	-	Mechanosensitive ion channel
HAPAPPHC_02322	7.74e-136	-	-	-	MP	-	-	-	NlpE N-terminal domain
HAPAPPHC_02323	1.44e-296	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
HAPAPPHC_02324	6.59e-124	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HAPAPPHC_02325	1.98e-38	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HAPAPPHC_02326	1.07e-160	-	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
HAPAPPHC_02327	2.64e-107	-	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
HAPAPPHC_02328	0.0	pruA	1.2.1.88, 1.5.5.2	-	C	ko:K00294,ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko03000	1-pyrroline-5-carboxylate dehydrogenase
HAPAPPHC_02329	8.27e-35	-	-	-	C	-	-	-	4Fe-4S single cluster domain of Ferredoxin I
HAPAPPHC_02330	7.82e-161	-	-	-	S	ko:K09702	-	ko00000	Protein of unknown function (DUF1349)
HAPAPPHC_02331	8.98e-128	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HAPAPPHC_02332	0.0	acsA	6.2.1.1, 6.2.1.32	-	I	ko:K01895,ko:K08295	ko00010,ko00620,ko00627,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00627,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	AMP-binding enzyme C-terminal domain
HAPAPPHC_02333	1.39e-256	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HAPAPPHC_02334	7.42e-295	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HAPAPPHC_02335	0.0	-	-	-	T	-	-	-	PAS domain
HAPAPPHC_02336	2.32e-234	argF	2.1.3.11, 2.1.3.9	-	E	ko:K09065,ko:K13043	ko00220,ko01100,ko01230,map00220,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HAPAPPHC_02337	3.63e-66	-	-	-	T	-	-	-	Protein of unknown function (DUF3467)
HAPAPPHC_02338	2.26e-212	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HAPAPPHC_02339	4.97e-217	-	-	-	S	-	-	-	Endonuclease/Exonuclease/phosphatase family
HAPAPPHC_02340	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HAPAPPHC_02341	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HAPAPPHC_02342	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HAPAPPHC_02343	2.57e-60	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HAPAPPHC_02344	2.21e-115	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HAPAPPHC_02345	3.53e-160	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HAPAPPHC_02346	1.79e-100	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HAPAPPHC_02347	1.01e-122	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HAPAPPHC_02348	8.1e-36	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HAPAPPHC_02350	1.29e-131	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HAPAPPHC_02351	9.8e-39	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HAPAPPHC_02352	3.79e-75	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HAPAPPHC_02357	1.1e-61	raiA	-	-	J	ko:K05808	-	ko00000,ko03009	Ribosomal subunit interface protein
HAPAPPHC_02358	1.26e-213	xerC	-	-	L	ko:K03733	-	ko00000,ko03036	Belongs to the 'phage' integrase family
HAPAPPHC_02359	5.14e-34	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
HAPAPPHC_02360	6.82e-251	mtnA	5.3.1.23	-	E	ko:K08963	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
HAPAPPHC_02361	9.13e-203	-	-	-	-	-	-	-	-
HAPAPPHC_02362	1.15e-150	-	-	-	L	-	-	-	DNA-binding protein
HAPAPPHC_02363	0.0	-	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	peptidase M24
HAPAPPHC_02364	2.29e-101	dapH	-	-	S	-	-	-	acetyltransferase
HAPAPPHC_02365	1.02e-301	nylB	-	-	V	-	-	-	Beta-lactamase
HAPAPPHC_02366	2.67e-128	-	-	-	Q	-	-	-	Carbohydrate family 9 binding domain-like
HAPAPPHC_02367	3.22e-146	-	-	-	Q	-	-	-	Carbohydrate family 9 binding domain-like
HAPAPPHC_02368	0.0	pepC	3.4.22.40	-	M	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
HAPAPPHC_02369	3.36e-287	waaA	2.4.99.12, 2.4.99.13, 2.4.99.14, 2.4.99.15	GT30	M	ko:K02527	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	transferase
HAPAPPHC_02370	0.0	gltX	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HAPAPPHC_02371	0.0	-	-	-	S	ko:K07037	-	ko00000	7TM receptor with intracellular HD hydrolase
HAPAPPHC_02372	3.17e-280	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HAPAPPHC_02373	1.43e-174	-	-	-	S	-	-	-	Domain of unknown function (DUF4469) with IG-like fold
HAPAPPHC_02374	0.00054	-	-	-	-	ko:K12516	-	ko00000,ko02000,ko02044	-
HAPAPPHC_02375	0.0	-	-	-	L	-	-	-	endonuclease I
HAPAPPHC_02376	7.12e-25	-	-	-	-	-	-	-	-
HAPAPPHC_02377	6.28e-73	-	-	-	DJ	-	-	-	Psort location Cytoplasmic, score 8.96
HAPAPPHC_02378	7.02e-119	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HAPAPPHC_02379	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HAPAPPHC_02380	1.7e-139	-	-	-	M	-	-	-	Outer membrane protein beta-barrel domain
HAPAPPHC_02381	5.24e-201	-	2.7.1.33	-	H	ko:K09680	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenate kinase
HAPAPPHC_02382	0.0	mutB	5.4.99.2	-	I	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Methylmalonyl-CoA mutase
HAPAPPHC_02383	0.0	mutA	5.4.99.2	-	I	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Methylmalonyl-CoA mutase
HAPAPPHC_02385	0.0	-	-	-	GM	-	-	-	NAD(P)H-binding
HAPAPPHC_02386	4.01e-48	-	-	-	S	-	-	-	Winged helix-turn-helix domain (DUF2582)
HAPAPPHC_02387	1.3e-205	-	5.1.3.30, 5.1.3.31	-	G	ko:K18910	-	ko00000,ko01000	Xylose isomerase-like TIM barrel
HAPAPPHC_02388	5.51e-308	-	3.1.3.1	-	S	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko01000	phosphodiesterase
HAPAPPHC_02389	0.0	-	-	-	P	-	-	-	Carboxypeptidase regulatory-like domain
HAPAPPHC_02390	0.0	-	-	-	P	-	-	-	Carboxypeptidase regulatory-like domain
HAPAPPHC_02391	0.0	-	-	-	L	-	-	-	COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member
HAPAPPHC_02392	1.19e-209	-	-	-	O	-	-	-	prohibitin homologues
HAPAPPHC_02393	8.48e-28	-	-	-	S	-	-	-	Arc-like DNA binding domain
HAPAPPHC_02394	8.98e-232	-	-	-	S	-	-	-	Sporulation and cell division repeat protein
HAPAPPHC_02395	0.0	-	3.1.6.1	-	P	ko:K01130	ko00140,ko00600,map00140,map00600	ko00000,ko00001,ko01000	Arylsulfatase
HAPAPPHC_02396	2e-106	-	-	-	F	ko:K21572	-	ko00000,ko02000	SusD family
HAPAPPHC_02397	1.48e-259	-	-	-	F	ko:K21572	-	ko00000,ko02000	SusD family
HAPAPPHC_02398	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HAPAPPHC_02399	8.07e-69	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HAPAPPHC_02400	3.66e-253	-	-	-	PT	-	-	-	Sigma factor regulatory protein, FecR PupR family
HAPAPPHC_02401	2.58e-147	-	-	-	L	-	-	-	COG COG2801 Transposase and inactivated derivatives
HAPAPPHC_02402	8.71e-52	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
HAPAPPHC_02403	1.85e-155	-	-	-	K	ko:K03088	-	ko00000,ko03021	RNA polymerase sigma-70 factor, ECF subfamily
HAPAPPHC_02404	0.0	-	-	-	P	-	-	-	COG COG3119 Arylsulfatase A and related enzymes
HAPAPPHC_02405	0.0	-	3.1.6.1	-	P	ko:K01130	ko00140,ko00600,map00140,map00600	ko00000,ko00001,ko01000	Arylsulfatase
HAPAPPHC_02406	0.0	-	3.1.6.1	-	P	ko:K01130	ko00140,ko00600,map00140,map00600	ko00000,ko00001,ko01000	Arylsulfatase
HAPAPPHC_02407	0.0	-	-	-	F	ko:K21572	-	ko00000,ko02000	SusD family
HAPAPPHC_02408	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HAPAPPHC_02409	4.68e-234	-	-	-	PT	-	-	-	Domain of unknown function (DUF4974)
HAPAPPHC_02410	1.92e-133	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70, region 4
HAPAPPHC_02411	3.05e-152	-	-	-	KT	-	-	-	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HAPAPPHC_02412	4.15e-171	-	-	-	S	-	-	-	ATPase domain predominantly from Archaea
HAPAPPHC_02413	2.12e-68	-	-	-	S	-	-	-	ATPase domain predominantly from Archaea
HAPAPPHC_02414	4.96e-176	-	-	-	T	ko:K02477	-	ko00000,ko02022	COG3279 Response regulator of the LytR AlgR family
HAPAPPHC_02415	5.38e-251	-	-	-	I	-	-	-	Alpha/beta hydrolase family
HAPAPPHC_02416	0.0	-	-	-	S	-	-	-	Capsule assembly protein Wzi
HAPAPPHC_02417	1.1e-174	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HAPAPPHC_02418	1.02e-06	-	-	-	-	-	-	-	-
HAPAPPHC_02419	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 92
HAPAPPHC_02420	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	SusD family
HAPAPPHC_02421	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HAPAPPHC_02422	2.61e-157	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HAPAPPHC_02423	1.86e-217	-	-	-	PT	-	-	-	Domain of unknown function (DUF4974)
HAPAPPHC_02424	7.56e-129	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70, region 4
HAPAPPHC_02425	3.12e-250	-	4.1.1.81	-	E	ko:K04720	ko00860,map00860	ko00000,ko00001,ko01000	Aminotransferase
HAPAPPHC_02426	0.0	nagA	-	-	G	-	-	-	hydrolase, family 3
HAPAPPHC_02427	0.0	-	-	-	P	-	-	-	TonB-dependent receptor plug domain
HAPAPPHC_02428	1.87e-249	-	-	-	S	-	-	-	Domain of unknown function (DUF4249)
HAPAPPHC_02429	7.83e-73	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HAPAPPHC_02430	2.52e-21	-	-	-	DN	-	-	-	SMART transglutaminase domain-containing protein
HAPAPPHC_02431	7.45e-24	-	-	-	N	-	-	-	Leucine rich repeats (6 copies)
HAPAPPHC_02433	1.66e-122	-	-	-	S	-	-	-	Protein of unknown function (DUF3990)
HAPAPPHC_02434	1.3e-47	-	-	-	S	-	-	-	Protein of unknown function (DUF3791)
HAPAPPHC_02435	0.0	-	-	-	P	-	-	-	Psort location OuterMembrane, score
HAPAPPHC_02436	0.0	-	-	-	KT	-	-	-	response regulator
HAPAPPHC_02437	4.16e-94	-	-	-	T	-	-	-	Histidine kinase
HAPAPPHC_02438	4.35e-154	-	-	-	T	-	-	-	Histidine kinase
HAPAPPHC_02439	1.08e-169	-	-	-	KT	ko:K02477	-	ko00000,ko02022	COG3279 Response regulator of the LytR AlgR family
HAPAPPHC_02440	3e-98	-	-	-	K	-	-	-	LytTr DNA-binding domain
HAPAPPHC_02441	5.04e-134	-	-	-	L	-	-	-	COG COG2801 Transposase and inactivated derivatives
HAPAPPHC_02442	8.71e-52	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
HAPAPPHC_02443	3.88e-283	-	-	-	I	-	-	-	COG NOG24984 non supervised orthologous group
HAPAPPHC_02444	2.95e-177	-	-	-	S	-	-	-	Domain of unknown function (DUF4270)
HAPAPPHC_02445	3.24e-110	-	-	-	S	-	-	-	Domain of unknown function (DUF4270)
HAPAPPHC_02446	3.16e-117	nanM	-	-	S	-	-	-	Kelch repeat type 1-containing protein
HAPAPPHC_02447	4.88e-73	-	-	-	S	-	-	-	Domain of unknown function (DUF4907)
HAPAPPHC_02448	6.03e-307	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HAPAPPHC_02450	1.6e-103	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	50S ribosomal protein L17
HAPAPPHC_02451	1.19e-232	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HAPAPPHC_02452	1.92e-135	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HAPAPPHC_02453	1.01e-86	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HAPAPPHC_02454	5.07e-81	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HAPAPPHC_02455	3.05e-18	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
HAPAPPHC_02456	1.4e-44	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HAPAPPHC_02457	1.64e-193	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
HAPAPPHC_02458	8.77e-296	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HAPAPPHC_02459	2.44e-94	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
HAPAPPHC_02460	1.01e-31	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	50S ribosomal protein L30
HAPAPPHC_02461	6.42e-112	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HAPAPPHC_02462	1.72e-71	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HAPAPPHC_02463	4.81e-127	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HAPAPPHC_02464	3.51e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HAPAPPHC_02465	1.96e-54	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HAPAPPHC_02466	2.56e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HAPAPPHC_02467	7.55e-69	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HAPAPPHC_02468	1.13e-77	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HAPAPPHC_02469	8.54e-54	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HAPAPPHC_02470	1.02e-34	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
HAPAPPHC_02471	2.78e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HAPAPPHC_02472	2.57e-168	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HAPAPPHC_02473	1.07e-89	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HAPAPPHC_02474	2.12e-58	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HAPAPPHC_02475	3.16e-193	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HAPAPPHC_02476	5.79e-62	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HAPAPPHC_02477	1.28e-137	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
HAPAPPHC_02478	2.73e-146	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HAPAPPHC_02479	2.7e-62	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
HAPAPPHC_02480	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HAPAPPHC_02481	9.74e-108	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HAPAPPHC_02482	1.52e-89	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HAPAPPHC_02483	1.07e-135	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
HAPAPPHC_02484	2.02e-216	-	-	-	-	-	-	-	-
HAPAPPHC_02485	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HAPAPPHC_02486	2.81e-68	-	-	-	S	-	-	-	COG NOG23401 non supervised orthologous group
HAPAPPHC_02487	0.0	-	-	-	S	-	-	-	OstA-like protein
HAPAPPHC_02488	0.0	surA	5.2.1.8	-	M	ko:K03771	-	ko00000,ko01000,ko03110	peptidylprolyl isomerase
HAPAPPHC_02489	8.11e-201	-	-	-	O	-	-	-	COG NOG23400 non supervised orthologous group
HAPAPPHC_02490	0.0	-	5.2.1.8	-	M	ko:K03771	-	ko00000,ko01000,ko03110	peptidylprolyl isomerase
HAPAPPHC_02491	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HAPAPPHC_02492	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HAPAPPHC_02493	1.38e-292	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HAPAPPHC_02494	5.04e-154	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HAPAPPHC_02495	1.29e-315	tig	-	-	O	ko:K03545	-	ko00000	Trigger factor
HAPAPPHC_02496	1.63e-201	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HAPAPPHC_02497	9.35e-174	lptB	-	-	S	ko:K06861	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HAPAPPHC_02498	9.46e-287	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
HAPAPPHC_02499	1.38e-154	mlaE	-	-	Q	ko:K02066	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0767 ABC-type transport system involved in resistance to organic solvents, permease component
HAPAPPHC_02500	2.49e-181	metN	-	-	Q	ko:K02065	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HAPAPPHC_02501	1.67e-309	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HAPAPPHC_02503	2.72e-102	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HAPAPPHC_02504	3.64e-203	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HAPAPPHC_02505	1.23e-38	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HAPAPPHC_02506	3.96e-163	truB	5.4.99.25	-	J	ko:K03177	-	ko00000,ko01000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HAPAPPHC_02507	3.96e-183	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HAPAPPHC_02508	2.99e-49	fjo13	-	-	S	-	-	-	Protein of unknown function (DUF3098)
HAPAPPHC_02509	1.3e-185	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Belongs to the ABC-4 integral membrane protein family. FtsX subfamily
HAPAPPHC_02510	7.73e-36	-	-	-	S	-	-	-	PIN domain
HAPAPPHC_02512	0.0	-	-	-	N	-	-	-	Bacterial Ig-like domain 2
HAPAPPHC_02515	5.04e-119	-	-	-	S	-	-	-	Nucleotidyl transferase AbiEii toxin, Type IV TA system
HAPAPPHC_02516	4.81e-76	-	-	-	-	-	-	-	-
HAPAPPHC_02517	0.0	miaB	2.8.4.3	-	J	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HAPAPPHC_02519	0.0	scpC	2.8.3.18, 3.1.2.1	-	C	ko:K01067,ko:K18118	ko00020,ko00620,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00650,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	acetyl-CoA hydrolase
HAPAPPHC_02520	5.15e-269	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HAPAPPHC_02521	7.73e-200	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	phosphate transport system permease
HAPAPPHC_02522	4.49e-181	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HAPAPPHC_02523	9.74e-154	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
HAPAPPHC_02524	9.38e-297	-	-	-	M	-	-	-	Phosphate-selective porin O and P
HAPAPPHC_02525	0.0	-	3.2.1.51	GH95	G	ko:K15923	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65, N-terminal domain
HAPAPPHC_02526	0.0	msbA	-	-	V	ko:K06147,ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter, ATP-binding protein
HAPAPPHC_02527	7.1e-119	-	-	-	-	-	-	-	-
HAPAPPHC_02528	4.07e-17	-	-	-	-	-	-	-	-
HAPAPPHC_02529	7.02e-271	-	-	-	C	-	-	-	Radical SAM domain protein
HAPAPPHC_02530	0.0	-	-	-	G	-	-	-	Domain of unknown function (DUF4091)
HAPAPPHC_02531	0.0	bglB	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Fibronectin type III-like domain
HAPAPPHC_02532	2.63e-29	-	-	-	-	-	-	-	-
HAPAPPHC_02533	8.29e-76	-	-	-	-	-	-	-	-
HAPAPPHC_02534	5.02e-52	-	-	-	S	-	-	-	Protein of unknown function (DUF2442)
HAPAPPHC_02536	1.19e-141	-	-	-	-	-	-	-	-
HAPAPPHC_02537	2.9e-06	-	-	-	-	-	-	-	-
HAPAPPHC_02539	2.85e-316	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HAPAPPHC_02540	4.38e-209	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HAPAPPHC_02541	1.67e-250	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HAPAPPHC_02542	1.73e-40	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
HAPAPPHC_02543	1.36e-137	-	-	-	S	-	-	-	Uncharacterized ACR, COG1399
HAPAPPHC_02544	3.35e-269	vicK	-	-	T	-	-	-	Histidine kinase
HAPAPPHC_02545	1.46e-52	-	-	-	-	-	-	-	-
HAPAPPHC_02548	9.37e-118	-	-	-	S	-	-	-	Protein of unknown function (DUF4255)
HAPAPPHC_02550	4.85e-97	-	-	-	S	ko:K06907	-	ko00000	Phage tail sheath C-terminal domain
HAPAPPHC_02551	2.44e-104	-	-	-	S	-	-	-	T4-like virus tail tube protein gp19
HAPAPPHC_02552	1.93e-116	-	-	-	S	-	-	-	PFAM T4-like virus tail tube protein gp19
HAPAPPHC_02554	8.73e-154	-	-	-	S	-	-	-	LysM domain
HAPAPPHC_02555	2.12e-65	-	-	-	S	-	-	-	Phage late control gene D protein (GPD)
HAPAPPHC_02557	5.49e-203	-	-	-	S	-	-	-	Phage late control gene D protein (GPD)
HAPAPPHC_02558	1.17e-92	-	-	-	S	ko:K06903	-	ko00000	Gene 25-like lysozyme
HAPAPPHC_02559	0.0	-	-	-	S	-	-	-	homolog of phage Mu protein gp47
HAPAPPHC_02560	1.84e-187	-	-	-	-	-	-	-	-
HAPAPPHC_02561	0.0	-	-	-	H	-	-	-	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
HAPAPPHC_02563	0.0	-	-	-	O	-	-	-	ATPase family associated with various cellular activities (AAA)
HAPAPPHC_02564	6.3e-62	-	-	-	S	-	-	-	positive regulation of growth rate
HAPAPPHC_02565	1.99e-220	-	-	-	D	-	-	-	peptidase
HAPAPPHC_02566	4.28e-91	-	-	-	D	-	-	-	peptidase
HAPAPPHC_02567	0.0	-	-	-	G	-	-	-	Domain of Unknown Function (DUF1080)
HAPAPPHC_02568	0.0	-	-	-	S	-	-	-	NPCBM/NEW2 domain
HAPAPPHC_02569	2.3e-273	-	-	-	S	-	-	-	NPCBM/NEW2 domain
HAPAPPHC_02570	1.6e-64	-	-	-	-	-	-	-	-
HAPAPPHC_02571	5.25e-306	-	-	-	S	-	-	-	Protein of unknown function (DUF2961)
HAPAPPHC_02572	0.0	-	-	-	G	-	-	-	Putative collagen-binding domain of a collagenase
HAPAPPHC_02573	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 28 family
HAPAPPHC_02574	0.0	-	-	-	Q	ko:K21572	-	ko00000,ko02000	pyridine nucleotide-disulphide oxidoreductase
HAPAPPHC_02575	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HAPAPPHC_02576	6.72e-233	-	-	-	PT	-	-	-	Domain of unknown function (DUF4974)
HAPAPPHC_02577	1.36e-125	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70, region 4
HAPAPPHC_02578	0.0	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HAPAPPHC_02579	4.18e-168	-	-	-	C	-	-	-	Domain of Unknown Function (DUF1080)
HAPAPPHC_02580	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	Pfam:SusD
HAPAPPHC_02581	0.0	-	-	-	P	-	-	-	TonB dependent receptor
HAPAPPHC_02582	6.81e-250	-	-	-	PT	-	-	-	Domain of unknown function (DUF4974)
HAPAPPHC_02583	9.29e-123	-	-	-	K	-	-	-	Sigma-70, region 4
HAPAPPHC_02584	0.0	-	-	-	H	-	-	-	Outer membrane protein beta-barrel family
HAPAPPHC_02585	0.0	-	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HAPAPPHC_02586	5.67e-176	rprY	-	-	K	-	-	-	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HAPAPPHC_02587	1.95e-315	cstA	-	-	T	ko:K06200	-	ko00000	Carbon starvation protein
HAPAPPHC_02588	1.62e-67	-	-	-	S	ko:K09117	-	ko00000	Glutamyl-tRNA amidotransferase
HAPAPPHC_02589	2.31e-311	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HAPAPPHC_02590	6e-290	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HAPAPPHC_02591	2.58e-167	ftsQ	-	-	M	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein FtsQ
HAPAPPHC_02592	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
HAPAPPHC_02593	7.84e-264	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HAPAPPHC_02594	5.48e-298	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HAPAPPHC_02595	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HAPAPPHC_02596	6.12e-296	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HAPAPPHC_02597	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HAPAPPHC_02598	0.0	ftsI	3.4.16.4	-	M	ko:K03587	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011,ko03036	Penicillin-binding protein, transpeptidase domain protein
HAPAPPHC_02599	1.15e-75	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HAPAPPHC_02600	6.65e-109	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HAPAPPHC_02601	1.47e-93	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HAPAPPHC_02602	2.45e-198	-	-	-	I	-	-	-	Acyltransferase
HAPAPPHC_02603	1.99e-237	-	-	-	S	-	-	-	Hemolysin
HAPAPPHC_02604	7.19e-179	-	-	-	S	-	-	-	Exopolysaccharide biosynthesis protein YbjH
HAPAPPHC_02605	3.41e-120	-	-	-	-	-	-	-	-
HAPAPPHC_02606	1.08e-265	-	-	-	-	-	-	-	-
HAPAPPHC_02607	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HAPAPPHC_02608	8.29e-129	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
HAPAPPHC_02609	1.42e-125	-	-	-	S	-	-	-	Protein of unknown function (DUF3822)
HAPAPPHC_02610	9.66e-60	-	-	-	S	-	-	-	Protein of unknown function (DUF3822)
HAPAPPHC_02611	1.29e-147	-	-	-	S	-	-	-	COG NOG19144 non supervised orthologous group
HAPAPPHC_02612	0.0	recD2_2	3.1.11.5	-	L	ko:K01144	-	ko00000,ko01000	COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member
HAPAPPHC_02613	2.42e-130	-	-	-	S	-	-	-	COG NOG23390 non supervised orthologous group
HAPAPPHC_02614	7.41e-163	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HAPAPPHC_02615	7.53e-161	-	-	-	S	-	-	-	Transposase
HAPAPPHC_02616	1.45e-167	yjjG	-	-	S	ko:K07025	-	ko00000	Hydrolase
HAPAPPHC_02617	8.23e-247	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HAPAPPHC_02618	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HAPAPPHC_02619	2.09e-209	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HAPAPPHC_02620	8.64e-125	-	-	-	S	-	-	-	Domain of unknown function (DUF4924)
HAPAPPHC_02621	1.74e-223	mpl	6.3.2.45, 6.3.2.8	-	M	ko:K01924,ko:K02558	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Mur ligase middle domain
HAPAPPHC_02622	0.0	-	-	-	U	-	-	-	WD40-like Beta Propeller Repeat
HAPAPPHC_02623	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HAPAPPHC_02624	0.0	-	-	-	S	-	-	-	Predicted AAA-ATPase
HAPAPPHC_02625	1.24e-12	-	-	-	S	-	-	-	Domain of unknown function (DUF4934)
HAPAPPHC_02626	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	Pfam:SusD
HAPAPPHC_02627	0.0	-	-	-	P	-	-	-	TonB dependent receptor
HAPAPPHC_02628	3.35e-213	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
HAPAPPHC_02629	2.19e-205	nagZ2	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycosyl hydrolase family 20, catalytic domain
HAPAPPHC_02630	0.0	nagZ2	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycosyl hydrolase family 20, catalytic domain
HAPAPPHC_02631	0.0	-	-	-	EU	-	-	-	Peptidase, S9A B C family, catalytic domain protein
HAPAPPHC_02632	0.0	-	-	-	P	-	-	-	TonB dependent receptor
HAPAPPHC_02633	0.0	-	-	-	J	ko:K21572	-	ko00000,ko02000	SusD family
HAPAPPHC_02634	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate
HAPAPPHC_02635	2.41e-150	-	-	-	-	-	-	-	-
HAPAPPHC_02636	0.0	-	-	-	P	-	-	-	Carboxypeptidase regulatory-like domain
HAPAPPHC_02637	0.0	-	-	-	S	-	-	-	C terminal of Calcineurin-like phosphoesterase
HAPAPPHC_02638	1.6e-309	-	-	-	S	ko:K07133	-	ko00000	AAA domain
HAPAPPHC_02639	5.32e-12	-	-	-	-	-	-	-	-
HAPAPPHC_02641	1.19e-255	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HAPAPPHC_02642	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HAPAPPHC_02643	2.07e-236	-	-	-	M	-	-	-	Peptidase, M23
HAPAPPHC_02644	1.23e-75	ycgE	-	-	K	-	-	-	Transcriptional regulator
HAPAPPHC_02645	5.15e-91	-	-	-	L	-	-	-	Domain of unknown function (DUF3127)
HAPAPPHC_02646	1.02e-210	yrbG	-	-	P	ko:K07301	-	ko00000,ko02000	K -dependent Na Ca exchanger
HAPAPPHC_02647	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HAPAPPHC_02648	9.78e-107	lrp	-	-	K	ko:K03719,ko:K05800	-	ko00000,ko03000,ko03036	helix_turn_helix ASNC type
HAPAPPHC_02649	5.18e-309	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	O-acetylhomoserine aminocarboxypropyltransferase
HAPAPPHC_02650	1.48e-85	-	-	-	S	-	-	-	COG NOG30654 non supervised orthologous group
HAPAPPHC_02651	3.14e-177	-	-	-	T	ko:K02477	-	ko00000,ko02022	LytTr DNA-binding domain
HAPAPPHC_02652	1.93e-242	-	-	-	T	-	-	-	Histidine kinase
HAPAPPHC_02653	0.0	mltD	-	-	M	ko:K08307	-	ko00000,ko01000,ko01011	transglycosylase
HAPAPPHC_02654	1.69e-169	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HAPAPPHC_02655	6.63e-201	parB	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HAPAPPHC_02656	2.48e-178	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Chromosome partitioning protein ParA
HAPAPPHC_02657	0.0	-	-	-	-	-	-	-	-
HAPAPPHC_02658	1.56e-79	-	-	-	-	-	-	-	-
HAPAPPHC_02659	1.83e-180	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Biotin/lipoate A/B protein ligase family
HAPAPPHC_02660	2.29e-85	-	-	-	S	-	-	-	YjbR
HAPAPPHC_02661	1.18e-90	-	-	-	L	ko:K07460	-	ko00000	Belongs to the UPF0102 family
HAPAPPHC_02662	3.12e-47	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HAPAPPHC_02663	4.77e-100	tadA	3.5.4.33	-	FJ	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HAPAPPHC_02664	2.7e-33	-	-	-	S	-	-	-	Domain of unknown function (DUF4834)
HAPAPPHC_02665	3.81e-160	pssA	2.7.8.8	-	I	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HAPAPPHC_02666	1.02e-153	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
HAPAPPHC_02667	1.05e-107	addA	-	-	L	-	-	-	Belongs to the helicase family. UvrD subfamily
HAPAPPHC_02668	1.56e-218	addA	-	-	L	-	-	-	Belongs to the helicase family. UvrD subfamily
HAPAPPHC_02669	0.0	addA	-	-	L	-	-	-	Belongs to the helicase family. UvrD subfamily
HAPAPPHC_02670	2.64e-75	-	-	-	J	ko:K03113	ko03013,map03013	ko00000,ko00001,ko03012	Translation initiation factor
HAPAPPHC_02671	7.8e-176	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
HAPAPPHC_02672	0.0	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
HAPAPPHC_02673	4.62e-112	ispF	4.6.1.12	-	I	ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HAPAPPHC_02674	1.04e-291	porV	-	-	I	-	-	-	Psort location OuterMembrane, score
HAPAPPHC_02675	0.0	porU	-	-	S	-	-	-	Peptidase family C25
HAPAPPHC_02676	1.78e-146	fahA	-	-	Q	-	-	-	2-hydroxyhepta-2,4-diene-1,7-dioate isomerase
HAPAPPHC_02677	1.24e-152	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HAPAPPHC_02678	3.17e-191	-	-	-	K	-	-	-	BRO family, N-terminal domain
HAPAPPHC_02679	2.97e-27	-	-	-	-	-	-	-	-
HAPAPPHC_02680	4.71e-199	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
HAPAPPHC_02681	0.0	-	-	-	E	ko:K01270	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Catalyzes the hydrolysis of Xaa-His dipeptides
HAPAPPHC_02682	5.26e-235	-	-	-	S	ko:K07027	-	ko00000,ko02000	Lysylphosphatidylglycerol synthase TM region
HAPAPPHC_02683	4.68e-191	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HAPAPPHC_02684	7.28e-289	mgtE	-	-	P	ko:K06213	-	ko00000,ko02000	Acts as a magnesium transporter
HAPAPPHC_02685	1.36e-58	-	-	-	S	ko:K06518	-	ko00000,ko02000	Murein hydrolase
HAPAPPHC_02686	1.07e-146	lrgB	-	-	M	-	-	-	TIGR00659 family
HAPAPPHC_02687	9.29e-132	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HAPAPPHC_02688	2.68e-161	radC	-	-	E	ko:K03630	-	ko00000	Belongs to the UPF0758 family
HAPAPPHC_02689	1.16e-30	yitW	-	-	S	-	-	-	FeS assembly SUF system protein
HAPAPPHC_02690	6.84e-19	yitW	-	-	S	-	-	-	FeS assembly SUF system protein
HAPAPPHC_02691	3.07e-197	lpxH	3.6.1.54	-	S	ko:K03269	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	UDP-2,3-diacylglucosamine hydrolase
HAPAPPHC_02692	1.44e-188	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HAPAPPHC_02693	2.25e-307	-	-	-	P	-	-	-	phosphate-selective porin O and P
HAPAPPHC_02694	1.01e-253	-	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	2-nitropropane dioxygenase
HAPAPPHC_02695	0.0	-	-	-	M	-	-	-	Domain of unknown function, B. Theta Gene description (DUF3868)
HAPAPPHC_02696	1.61e-141	-	-	-	M	-	-	-	Protein of unknown function (DUF3575)
HAPAPPHC_02697	1.71e-139	-	-	-	K	-	-	-	Transcriptional regulator, LuxR family
HAPAPPHC_02698	8.39e-181	-	-	-	D	ko:K07322	-	ko00000	Di-iron-containing protein involved in the repair of iron-sulfur clusters
HAPAPPHC_02699	6.65e-282	-	-	-	J	-	-	-	translation initiation inhibitor, yjgF family
HAPAPPHC_02700	8e-163	-	-	-	-	-	-	-	-
HAPAPPHC_02701	1.41e-306	-	-	-	P	-	-	-	phosphate-selective porin O and P
HAPAPPHC_02702	0.0	-	-	-	C	-	-	-	Di-haem oxidoreductase, putative peroxidase
HAPAPPHC_02703	5.85e-295	-	-	-	P	ko:K07231	-	ko00000	Imelysin
HAPAPPHC_02704	0.0	-	-	-	S	-	-	-	Psort location OuterMembrane, score
HAPAPPHC_02705	8.2e-214	-	-	-	-	-	-	-	-
HAPAPPHC_02707	8.28e-120	arsA	-	-	P	-	-	-	Domain of unknown function
HAPAPPHC_02708	2.48e-205	arsA	-	-	P	-	-	-	Domain of unknown function
HAPAPPHC_02709	0.0	-	-	-	P	-	-	-	Type I phosphodiesterase / nucleotide pyrophosphatase
HAPAPPHC_02710	9.05e-152	-	-	-	E	-	-	-	Translocator protein, LysE family
HAPAPPHC_02711	5.71e-152	-	-	-	T	-	-	-	Carbohydrate-binding family 9
HAPAPPHC_02712	1.03e-91	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.46
HAPAPPHC_02713	1.77e-136	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HAPAPPHC_02714	9.39e-71	-	-	-	-	-	-	-	-
HAPAPPHC_02715	0.0	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
HAPAPPHC_02716	3.92e-275	-	-	-	T	-	-	-	Histidine kinase-like ATPases
HAPAPPHC_02717	0.0	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence
HAPAPPHC_02718	4.04e-52	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HAPAPPHC_02719	1.1e-150	-	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HAPAPPHC_02720	2.54e-215	thiD	2.7.1.49, 2.7.4.7	-	K	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	transcriptional regulator (AraC family)
HAPAPPHC_02721	6.18e-28	-	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	regulation of translation
HAPAPPHC_02722	1.76e-258	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
HAPAPPHC_02723	0.0	-	-	-	S	-	-	-	Pfam Oxidoreductase family, NAD-binding Rossmann fold
HAPAPPHC_02724	0.0	-	-	-	T	-	-	-	COG NOG26059 non supervised orthologous group
HAPAPPHC_02725	2.99e-125	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HAPAPPHC_02727	9.44e-169	-	-	-	G	-	-	-	Phosphoglycerate mutase family
HAPAPPHC_02728	3.57e-159	-	-	-	S	-	-	-	Zeta toxin
HAPAPPHC_02729	4.51e-197	kdsB	2.7.7.38	-	M	ko:K00979	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
HAPAPPHC_02730	0.0	-	-	-	-	-	-	-	-
HAPAPPHC_02731	0.0	-	-	-	-	-	-	-	-
HAPAPPHC_02732	1.13e-197	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
HAPAPPHC_02733	3.17e-188	surE	3.1.3.5	-	S	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
HAPAPPHC_02734	1.68e-274	lpxB	2.4.1.182	GT19	M	ko:K00748	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HAPAPPHC_02735	8.73e-185	-	-	-	S	-	-	-	NigD-like N-terminal OB domain
HAPAPPHC_02736	3.41e-119	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70, region 4
HAPAPPHC_02737	1.14e-118	-	-	-	-	-	-	-	-
HAPAPPHC_02738	7.29e-199	-	-	-	-	-	-	-	-
HAPAPPHC_02740	2.66e-126	rpoE	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70, region 4
HAPAPPHC_02741	1.93e-87	-	-	-	-	-	-	-	-
HAPAPPHC_02742	0.0	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HAPAPPHC_02743	3.21e-120	-	1.8.5.2	-	S	ko:K16937	ko00920,ko01120,map00920,map01120	ko00000,ko00001,ko01000	DoxX
HAPAPPHC_02744	2.19e-131	-	-	-	G	-	-	-	Domain of Unknown Function (DUF1080)
HAPAPPHC_02745	6.31e-46	-	-	-	G	-	-	-	Domain of Unknown Function (DUF1080)
HAPAPPHC_02746	0.0	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HAPAPPHC_02747	1.27e-37	-	-	-	S	-	-	-	Domain of unknown function (DUF4492)
HAPAPPHC_02748	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
HAPAPPHC_02749	2.3e-275	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome C oxidase assembly protein
HAPAPPHC_02750	0.0	-	-	-	S	-	-	-	Peptidase family M28
HAPAPPHC_02751	3.13e-224	rnz	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HAPAPPHC_02752	1.1e-29	-	-	-	-	-	-	-	-
HAPAPPHC_02753	0.0	-	-	-	-	-	-	-	-
HAPAPPHC_02755	4.55e-196	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
HAPAPPHC_02756	1.67e-141	-	-	-	S	-	-	-	Protein of unknown function (DUF3109)
HAPAPPHC_02757	0.0	gpmI	5.4.2.12	-	G	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HAPAPPHC_02758	1.13e-131	-	-	-	S	ko:K07043	-	ko00000	Protein of unknown function DUF45
HAPAPPHC_02759	0.0	-	-	-	P	-	-	-	TonB dependent receptor
HAPAPPHC_02760	0.0	sprA	-	-	S	-	-	-	Motility related/secretion protein
HAPAPPHC_02761	5.9e-123	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HAPAPPHC_02762	3.51e-180	-	3.1.1.17	-	G	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	ko00000,ko00001,ko00002,ko01000,ko04147	SMP-30/Gluconolaconase/LRE-like region
HAPAPPHC_02763	1.37e-315	trkH	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium transporter
HAPAPPHC_02764	2.04e-11	trkH	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium transporter
HAPAPPHC_02765	0.0	trkA	-	-	P	ko:K03499	-	ko00000,ko02000	Potassium transporter
HAPAPPHC_02766	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HAPAPPHC_02769	0.0	-	-	-	T	-	-	-	Tetratricopeptide repeat protein
HAPAPPHC_02770	9e-182	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase family
HAPAPPHC_02771	1.55e-150	-	-	-	P	-	-	-	TonB-dependent Receptor Plug Domain
HAPAPPHC_02772	0.0	-	-	-	M	-	-	-	TamB, inner membrane protein subunit of TAM complex
HAPAPPHC_02773	0.0	-	-	-	M	-	-	-	Outer membrane protein, OMP85 family
HAPAPPHC_02774	0.0	-	-	-	-	-	-	-	-
HAPAPPHC_02775	6.05e-219	rocF	3.5.3.1, 3.5.3.11	-	E	ko:K01476,ko:K01480	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
HAPAPPHC_02776	1.24e-99	rocD	2.6.1.13	-	E	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HAPAPPHC_02777	4.69e-181	rocD	2.6.1.13	-	E	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HAPAPPHC_02778	7.19e-281	-	-	-	I	-	-	-	Acyltransferase
HAPAPPHC_02779	8.74e-235	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HAPAPPHC_02780	1.35e-264	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HAPAPPHC_02781	1.29e-141	pknB	2.7.11.1, 6.3.2.4	-	S	ko:K01921,ko:K08884,ko:K12132	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01001,ko01011	PASTA domain protein
HAPAPPHC_02782	1.85e-26	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L34
HAPAPPHC_02783	0.0	-	-	-	-	-	-	-	-
HAPAPPHC_02787	1.48e-27	-	-	-	S	-	-	-	Tetratricopeptide repeat protein
HAPAPPHC_02788	4.72e-108	-	-	-	S	-	-	-	Tetratricopeptide repeat protein
HAPAPPHC_02789	1.42e-43	-	4.1.1.3	-	C	ko:K01573	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	Oxaloacetate decarboxylase, gamma chain
HAPAPPHC_02790	0.0	-	6.4.1.1	-	C	ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Oxaloacetate decarboxylase
HAPAPPHC_02791	2.1e-53	-	6.4.1.1	-	C	ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Oxaloacetate decarboxylase
HAPAPPHC_02792	3.3e-280	-	4.1.1.3	-	C	ko:K01572	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	Na+-transporting oxaloacetate decarboxylase beta subunit
HAPAPPHC_02793	0.0	-	-	-	A	-	-	-	Domain of Unknown Function (DUF349)
HAPAPPHC_02794	1.27e-272	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HAPAPPHC_02795	1.06e-197	-	-	-	P	ko:K07214	-	ko00000	Carbohydrate-binding module 48 (Isoamylase N-terminal domain)
HAPAPPHC_02796	8.65e-66	-	-	-	P	ko:K07214	-	ko00000	Carbohydrate-binding module 48 (Isoamylase N-terminal domain)
HAPAPPHC_02797	5.64e-161	-	-	-	T	-	-	-	LytTr DNA-binding domain
HAPAPPHC_02798	2.47e-245	-	-	-	T	-	-	-	Histidine kinase
HAPAPPHC_02799	0.0	-	-	-	H	-	-	-	Outer membrane protein beta-barrel family
HAPAPPHC_02800	2.71e-30	-	-	-	-	-	-	-	-
HAPAPPHC_02801	1.04e-63	yafQ2	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	TIGRFAM addiction module toxin component, YafQ family
HAPAPPHC_02802	1.36e-137	folE	3.5.4.16	-	F	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
HAPAPPHC_02803	8.5e-116	-	-	-	S	-	-	-	Sporulation related domain
HAPAPPHC_02804	6.35e-177	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HAPAPPHC_02805	0.0	-	-	-	S	-	-	-	DoxX family
HAPAPPHC_02806	1.68e-126	-	-	-	S	-	-	-	Domain of Unknown Function (DUF1599)
HAPAPPHC_02807	8.42e-281	mepM_1	-	-	M	-	-	-	peptidase
HAPAPPHC_02808	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HAPAPPHC_02809	1.76e-169	ispD	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HAPAPPHC_02810	1.02e-34	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HAPAPPHC_02811	2.09e-302	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HAPAPPHC_02812	0.0	aprN	-	-	O	-	-	-	Subtilase family
HAPAPPHC_02813	2.32e-109	asnC	-	-	K	ko:K03718	-	ko00000,ko03000	Transcriptional regulator
HAPAPPHC_02814	3.52e-162	fkpB	5.2.1.8	-	M	ko:K03772,ko:K03773	-	ko00000,ko01000,ko03110	peptidyl-prolyl cis-trans isomerase
HAPAPPHC_02815	1.04e-136	-	5.2.1.8	-	O	ko:K03772,ko:K03773	-	ko00000,ko01000,ko03110	Peptidyl-prolyl cis-trans isomerase
HAPAPPHC_02816	0.0	-	-	-	S	-	-	-	Major fimbrial subunit protein (FimA)
HAPAPPHC_02817	0.0	-	-	-	S	-	-	-	Major fimbrial subunit protein type IV, Fimbrillin, C-terminal
HAPAPPHC_02818	9.73e-226	-	-	-	S	-	-	-	Fimbrillin-A associated anchor proteins Mfa1 and Mfa2
HAPAPPHC_02819	1.34e-167	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HAPAPPHC_02820	0.0	-	-	-	-	-	-	-	-
HAPAPPHC_02821	5.32e-208	-	2.1.1.113	-	L	ko:K00590	-	ko00000,ko01000,ko02048	Belongs to the N(4) N(6)-methyltransferase family
HAPAPPHC_02822	1.17e-61	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
HAPAPPHC_02823	3.85e-181	-	-	-	S	-	-	-	MvaI/BcnI restriction endonuclease family
HAPAPPHC_02824	2.72e-237	-	-	-	S	-	-	-	Putative carbohydrate metabolism domain
HAPAPPHC_02825	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na+/H+ antiporter family
HAPAPPHC_02826	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na+/H+ antiporter family
HAPAPPHC_02827	5.62e-243	sstT	-	-	U	-	-	-	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HAPAPPHC_02828	4.66e-133	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HAPAPPHC_02829	0.0	-	-	-	M	ko:K08676	-	ko00000,ko01000,ko01002	Tricorn protease homolog
HAPAPPHC_02831	5.8e-59	-	-	-	S	-	-	-	Lysine exporter LysO
HAPAPPHC_02832	3.16e-137	-	-	-	S	-	-	-	Lysine exporter LysO
HAPAPPHC_02833	0.0	-	-	-	-	-	-	-	-
HAPAPPHC_02834	2.14e-188	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
HAPAPPHC_02835	3.4e-65	-	-	-	T	-	-	-	Histidine kinase
HAPAPPHC_02836	0.0	-	-	-	T	-	-	-	Histidine kinase
HAPAPPHC_02837	0.0	-	-	-	M	-	-	-	Tricorn protease homolog
HAPAPPHC_02839	8.72e-140	-	-	-	S	-	-	-	Lysine exporter LysO
HAPAPPHC_02840	7.27e-56	-	-	-	S	-	-	-	Lysine exporter LysO
HAPAPPHC_02841	4.15e-153	-	-	-	-	-	-	-	-
HAPAPPHC_02842	1.26e-55	-	-	-	K	ko:K03088	-	ko00000,ko03021	DNA-templated transcription, initiation
HAPAPPHC_02843	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 92
HAPAPPHC_02844	7.26e-67	-	-	-	S	-	-	-	Belongs to the UPF0145 family
HAPAPPHC_02845	4.32e-163	-	-	-	S	-	-	-	DinB superfamily
HAPAPPHC_02846	1.46e-52	-	-	-	-	-	-	-	-
HAPAPPHC_02849	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	F5 8 type C domain protein
HAPAPPHC_02850	0.0	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
HAPAPPHC_02851	6.67e-236	-	-	-	G	-	-	-	PFAM Xylose isomerase, TIM barrel domain
HAPAPPHC_02852	0.0	-	-	CE10	I	ko:K03929	-	ko00000,ko01000	Carboxylesterase family
HAPAPPHC_02853	2.02e-105	-	-	-	M	ko:K21572	-	ko00000,ko02000	COG NOG26547 non supervised orthologous group
HAPAPPHC_02854	1.36e-249	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HAPAPPHC_02855	4.47e-312	-	-	-	S	-	-	-	Oxidoreductase
HAPAPPHC_02856	5.83e-175	-	-	-	G	-	-	-	Domain of Unknown Function (DUF1080)
HAPAPPHC_02857	2.86e-231	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HAPAPPHC_02858	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HAPAPPHC_02859	3.57e-166	-	-	-	KT	-	-	-	LytTr DNA-binding domain
HAPAPPHC_02860	4.69e-283	-	-	-	-	-	-	-	-
HAPAPPHC_02862	9.73e-228	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HAPAPPHC_02863	0.0	fadD	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	Long-chain fatty acid--CoA ligase
HAPAPPHC_02864	1.9e-72	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator
HAPAPPHC_02865	6.91e-259	-	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
HAPAPPHC_02866	3.51e-88	hinT	-	-	FG	ko:K02503	-	ko00000,ko04147	HIT family hydrolase
HAPAPPHC_02867	4.13e-99	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HAPAPPHC_02868	4.26e-272	-	-	-	CO	-	-	-	Domain of unknown function (DUF4369)
HAPAPPHC_02869	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HAPAPPHC_02871	5.63e-103	-	-	-	M	ko:K11934	-	ko00000,ko02000	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HAPAPPHC_02872	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
HAPAPPHC_02873	0.0	-	-	-	S	ko:K07133	-	ko00000	Psort location Cytoplasmic, score 8.96
HAPAPPHC_02874	0.0	fumB	4.2.1.2	-	C	ko:K01676	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible hydration of fumarate to (S)- malate
HAPAPPHC_02875	0.0	-	3.4.21.50	-	O	ko:K01337	-	ko00000,ko01000,ko01002	Trypsin-like peptidase domain
HAPAPPHC_02876	4.45e-181	-	3.4.21.50	-	O	ko:K01337	-	ko00000,ko01000,ko01002	Trypsin-like peptidase domain
HAPAPPHC_02877	0.0	-	-	-	NU	-	-	-	Tetratricopeptide repeat protein
HAPAPPHC_02878	0.0	-	-	-	S	-	-	-	COG NOG28036 non supervised orthologous group
HAPAPPHC_02879	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
HAPAPPHC_02880	1.96e-54	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HAPAPPHC_02881	2.45e-134	-	-	-	K	-	-	-	Helix-turn-helix domain
HAPAPPHC_02882	0.0	-	-	-	IQ	ko:K00666	-	ko00000,ko01000,ko01004	AMP-binding enzyme C-terminal domain
HAPAPPHC_02883	7.52e-200	-	-	-	K	-	-	-	AraC family transcriptional regulator
HAPAPPHC_02884	5.68e-157	-	-	-	IQ	-	-	-	KR domain
HAPAPPHC_02885	0.0	ahcY	3.3.1.1	-	H	ko:K01251	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
HAPAPPHC_02886	6.35e-278	-	-	-	M	-	-	-	Glycosyltransferase Family 4
HAPAPPHC_02887	0.0	-	-	-	S	-	-	-	membrane
HAPAPPHC_02888	1.05e-176	-	-	-	M	-	-	-	Glycosyl transferase family 2
HAPAPPHC_02889	8.14e-38	-	-	-	K	-	-	-	Divergent AAA domain
HAPAPPHC_02890	5.12e-150	-	-	-	M	-	-	-	group 1 family protein
HAPAPPHC_02891	4.4e-97	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
HAPAPPHC_02892	7.03e-69	-	-	-	H	-	-	-	COG NOG04119 non supervised orthologous group
HAPAPPHC_02893	1.06e-130	-	-	-	M	-	-	-	Glycosyl transferases group 1
HAPAPPHC_02894	1.16e-123	-	-	-	M	-	-	-	PFAM Glycosyl transferase, group 1
HAPAPPHC_02895	7.41e-68	-	-	-	M	ko:K07011	-	ko00000	Glycosyltransferase like family 2
HAPAPPHC_02896	1.64e-87	-	-	-	M	-	-	-	Glycosyl transferases group 1
HAPAPPHC_02897	2.86e-46	-	-	-	S	-	-	-	Polysaccharide biosynthesis protein
HAPAPPHC_02898	3.33e-129	-	-	-	S	-	-	-	Polysaccharide biosynthesis protein
HAPAPPHC_02899	1.53e-51	-	-	-	L	-	-	-	DNA-binding protein
HAPAPPHC_02900	5.59e-252	-	1.1.1.335	-	S	ko:K13016	ko00520,map00520	ko00000,ko00001,ko01000,ko01005	Oxidoreductase, NAD-binding domain protein
HAPAPPHC_02902	8.75e-60	-	-	-	G	-	-	-	Cupin 2, conserved barrel domain protein
HAPAPPHC_02906	6.66e-161	degT	-	-	E	-	-	-	Belongs to the DegT DnrJ EryC1 family
HAPAPPHC_02907	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HAPAPPHC_02913	2.05e-98	-	-	-	S	-	-	-	Putative carbohydrate metabolism domain
HAPAPPHC_02914	1.79e-106	-	-	-	S	-	-	-	Putative carbohydrate metabolism domain
HAPAPPHC_02915	3.04e-143	-	-	-	NU	-	-	-	Tfp pilus assembly protein FimV
HAPAPPHC_02916	6.38e-169	-	-	-	S	-	-	-	Domain of unknown function (DUF4493)
HAPAPPHC_02917	1.59e-31	-	-	-	S	-	-	-	Domain of unknown function (DUF4493)
HAPAPPHC_02918	1.75e-70	-	-	-	S	-	-	-	Domain of unknown function (DUF4493)
HAPAPPHC_02920	2.03e-168	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HAPAPPHC_02921	0.0	comM	-	-	O	ko:K07391	-	ko00000	magnesium chelatase
HAPAPPHC_02922	3.72e-261	-	-	-	CO	-	-	-	Domain of unknown function (DUF4369)
HAPAPPHC_02923	0.0	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HAPAPPHC_02924	5.84e-253	oorB	1.2.7.11, 1.2.7.3	-	C	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	ferredoxin oxidoreductase subunit beta
HAPAPPHC_02925	0.0	porA	1.2.7.11, 1.2.7.3	-	C	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	2-oxoacid acceptor oxidoreductase, alpha subunit
HAPAPPHC_02926	7.03e-265	ald	1.4.1.1	-	E	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Alanine dehydrogenase/PNT, N-terminal domain
HAPAPPHC_02927	3.18e-118	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HAPAPPHC_02928	0.0	-	-	-	S	-	-	-	amine dehydrogenase activity
HAPAPPHC_02929	2.82e-281	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HAPAPPHC_02930	4.15e-171	-	-	-	M	-	-	-	Glycosyl transferase family 2
HAPAPPHC_02931	2.08e-198	-	-	-	G	-	-	-	Polysaccharide deacetylase
HAPAPPHC_02932	3.44e-152	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease H
HAPAPPHC_02933	1.8e-269	-	-	-	M	-	-	-	Mannosyltransferase
HAPAPPHC_02934	3.38e-251	-	-	-	M	-	-	-	Group 1 family
HAPAPPHC_02935	5.57e-214	-	-	-	-	-	-	-	-
HAPAPPHC_02936	5.94e-111	-	-	-	T	-	-	-	Lipopolysaccharide kinase (Kdo/WaaP) family
HAPAPPHC_02937	8.37e-52	-	-	-	T	-	-	-	Lipopolysaccharide kinase (Kdo/WaaP) family
HAPAPPHC_02938	7.99e-253	-	-	GT9	M	ko:K02843	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	glycosyl transferase family
HAPAPPHC_02939	1.78e-140	-	-	-	M	-	-	-	Protein of unknown function (DUF4254)
HAPAPPHC_02940	2.3e-158	-	-	-	KT	-	-	-	Transcriptional regulatory protein, C terminal
HAPAPPHC_02941	4.88e-184	-	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
HAPAPPHC_02942	2.93e-115	-	-	-	S	-	-	-	Protein of unknown function (Porph_ging)
HAPAPPHC_02943	0.0	-	-	-	P	-	-	-	Psort location OuterMembrane, score
HAPAPPHC_02944	3.32e-283	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HAPAPPHC_02946	5.33e-267	pdxB	1.1.1.290	-	H	ko:K03473	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate
HAPAPPHC_02947	2.07e-110	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HAPAPPHC_02948	4.31e-44	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HAPAPPHC_02949	1.47e-304	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HAPAPPHC_02950	2.23e-196	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HAPAPPHC_02951	0.0	-	3.4.21.50	-	E	ko:K01337	-	ko00000,ko01000,ko01002	Leucine-rich repeat (LRR) protein
HAPAPPHC_02952	2.76e-246	pfkA	2.7.1.11, 2.7.1.90	-	G	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HAPAPPHC_02953	0.0	-	-	-	H	-	-	-	GH3 auxin-responsive promoter
HAPAPPHC_02954	7.35e-62	-	-	-	I	-	-	-	Acid phosphatase homologues
HAPAPPHC_02955	1.8e-99	-	-	-	I	-	-	-	Acid phosphatase homologues
HAPAPPHC_02956	0.0	glaB	-	-	M	-	-	-	Parallel beta-helix repeats
HAPAPPHC_02957	1e-307	-	-	-	T	-	-	-	Histidine kinase-like ATPases
HAPAPPHC_02958	0.0	-	-	-	T	-	-	-	Sigma-54 interaction domain
HAPAPPHC_02959	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HAPAPPHC_02960	2.12e-16	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HAPAPPHC_02961	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HAPAPPHC_02962	1.47e-91	paaI	-	-	Q	ko:K02614	ko00360,map00360	ko00000,ko00001,ko01000	Thioesterase superfamily
HAPAPPHC_02963	1.21e-213	-	-	-	S	-	-	-	Protein of unknown function (DUF3108)
HAPAPPHC_02964	0.0	-	-	-	S	-	-	-	Bacterial Ig-like domain
HAPAPPHC_02965	4.39e-43	-	-	-	O	-	-	-	Belongs to the peptidase S8 family
HAPAPPHC_02966	6.49e-126	-	-	-	O	-	-	-	Belongs to the peptidase S8 family
HAPAPPHC_02971	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF2851)
HAPAPPHC_02972	3.98e-169	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the DapB family
HAPAPPHC_02973	0.0	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HAPAPPHC_02974	9.19e-208	lepB_1	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HAPAPPHC_02975	2.08e-152	-	-	-	C	-	-	-	WbqC-like protein
HAPAPPHC_02976	4.73e-266	phnW	2.6.1.37	-	E	ko:K03430	ko00440,ko01100,ko01120,map00440,map01100,map01120	ko00000,ko00001,ko01000,ko01007	Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily
HAPAPPHC_02977	1.9e-189	phnX	3.11.1.1	-	S	ko:K05306	ko00440,ko01100,ko01120,map00440,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the HAD-like hydrolase superfamily. PhnX family
HAPAPPHC_02978	5.17e-210	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HAPAPPHC_02979	2.58e-78	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HAPAPPHC_02980	8.83e-208	-	-	-	-	-	-	-	-
HAPAPPHC_02981	0.0	-	-	-	U	-	-	-	Phosphate transporter
HAPAPPHC_02982	1.24e-122	-	-	-	K	ko:K03088	-	ko00000,ko03021	RNA polymerase sigma-70 factor
HAPAPPHC_02986	4.63e-120	-	-	-	S	-	-	-	ATPase domain predominantly from Archaea
HAPAPPHC_02987	1.74e-92	-	-	-	L	-	-	-	DNA-binding protein
HAPAPPHC_02988	1.19e-116	-	3.5.1.28	-	V	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
HAPAPPHC_02989	2.79e-228	-	-	-	PT	-	-	-	Domain of unknown function (DUF4974)
HAPAPPHC_02990	0.0	-	-	-	P	-	-	-	TonB dependent receptor
HAPAPPHC_02991	0.0	-	-	-	M	ko:K21572	-	ko00000,ko02000	SusD family
HAPAPPHC_02992	0.0	-	-	-	S	-	-	-	Pfam Oxidoreductase family, NAD-binding Rossmann fold
HAPAPPHC_02993	6.65e-197	-	-	-	G	-	-	-	Domain of Unknown Function (DUF1080)
HAPAPPHC_02994	2.5e-173	-	3.5.99.6	-	G	ko:K02080,ko:K02564	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko01000	COG0363 6-phosphogluconolactonase Glucosamine-6-phosphate isomerase deaminase
HAPAPPHC_02995	1.79e-216	-	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	glucokinase
HAPAPPHC_02996	1.41e-281	-	-	-	G	-	-	-	Transporter, major facilitator family protein
HAPAPPHC_02997	0.0	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl-hydrolase 97 N-terminal
HAPAPPHC_02998	1.49e-164	hypB	-	-	H	ko:K22132	-	ko00000,ko03016	COGs COG1179 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 1
HAPAPPHC_02999	1.1e-147	lolD	-	-	V	ko:K09810	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner
HAPAPPHC_03000	0.0	-	-	-	-	-	-	-	-
HAPAPPHC_03002	5.05e-243	-	-	-	S	-	-	-	COG NOG32009 non supervised orthologous group
HAPAPPHC_03003	1.62e-260	-	-	-	S	-	-	-	Major fimbrial subunit protein type IV, Fimbrillin, C-terminal
HAPAPPHC_03004	4.77e-88	-	-	-	M	-	-	-	Domain of unknown function, B. Theta Gene description (DUF3868)
HAPAPPHC_03005	3.04e-222	-	-	-	M	-	-	-	Domain of unknown function, B. Theta Gene description (DUF3868)
HAPAPPHC_03006	2.02e-148	-	-	-	M	-	-	-	Protein of unknown function (DUF3575)
HAPAPPHC_03007	4.1e-223	-	-	-	L	-	-	-	COG NOG11942 non supervised orthologous group
HAPAPPHC_03008	0.0	-	-	-	P	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HAPAPPHC_03009	1.94e-114	-	-	-	L	-	-	-	Helix-hairpin-helix motif
HAPAPPHC_03010	0.000426	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HAPAPPHC_03013	6.01e-139	-	-	-	-	-	-	-	-
HAPAPPHC_03014	1.62e-40	-	-	-	-	-	-	-	-
HAPAPPHC_03015	2.21e-225	-	2.7.11.1	-	S	ko:K12132	-	ko00000,ko01000,ko01001	amino acid activation for nonribosomal peptide biosynthetic process
HAPAPPHC_03016	1.23e-180	-	-	-	S	-	-	-	AAA ATPase domain
HAPAPPHC_03017	7.88e-121	-	-	-	S	-	-	-	Conserved protein domain typically associated with flavoprotein
HAPAPPHC_03018	0.0	-	-	-	P	-	-	-	TonB-dependent receptor
HAPAPPHC_03019	1.29e-199	-	-	-	P	-	-	-	TonB-dependent receptor
HAPAPPHC_03020	0.0	agcS	-	-	E	ko:K03310	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
HAPAPPHC_03021	8.31e-300	-	-	-	NU	-	-	-	Lipid A 3-O-deacylase (PagL)
HAPAPPHC_03022	8.64e-294	-	-	-	S	-	-	-	Belongs to the peptidase M16 family
HAPAPPHC_03023	0.0	-	-	-	S	-	-	-	Predicted AAA-ATPase
HAPAPPHC_03024	0.0	-	-	-	S	-	-	-	Peptidase family M28
HAPAPPHC_03025	7.78e-136	kdsD	5.3.1.13	-	M	ko:K06041	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Iron dicitrate transport regulator FecR
HAPAPPHC_03026	1.23e-228	-	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
HAPAPPHC_03027	4.43e-250	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HAPAPPHC_03028	7.56e-307	-	3.6.4.13	-	L	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	Belongs to the DEAD box helicase family
HAPAPPHC_03029	2.7e-19	-	3.6.4.13	-	L	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	Belongs to the DEAD box helicase family
HAPAPPHC_03030	1.72e-214	-	-	-	K	ko:K18954	-	ko00000,ko03000	methylphosphotriester-DNA alkyltransferase and transcriptional regulator (AraC XylS family) K00567
HAPAPPHC_03031	5.19e-252	-	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HAPAPPHC_03032	0.0	bepE_1	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HAPAPPHC_03033	7.36e-311	oprM_1	-	-	MU	-	-	-	Efflux transporter, outer membrane factor
HAPAPPHC_03034	0.0	-	-	-	M	-	-	-	Peptidase family C69
HAPAPPHC_03035	6e-290	-	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Papain family cysteine protease
HAPAPPHC_03036	0.0	dpp7	-	-	E	-	-	-	peptidase
HAPAPPHC_03037	2.8e-311	-	-	-	S	-	-	-	membrane
HAPAPPHC_03038	0.0	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
HAPAPPHC_03039	3.35e-244	cap	-	-	S	-	-	-	Polysaccharide biosynthesis protein
HAPAPPHC_03040	7.75e-100	cap	-	-	S	-	-	-	Polysaccharide biosynthesis protein
HAPAPPHC_03041	3.1e-233	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HAPAPPHC_03042	5.77e-289	-	-	-	S	-	-	-	6-bladed beta-propeller
HAPAPPHC_03043	7.23e-81	-	-	-	S	-	-	-	Predicted AAA-ATPase
HAPAPPHC_03044	2.96e-253	-	-	-	S	-	-	-	Predicted AAA-ATPase
HAPAPPHC_03045	8.09e-188	-	-	-	T	-	-	-	Tetratricopeptide repeat protein
HAPAPPHC_03047	0.0	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
HAPAPPHC_03048	3.21e-160	-	-	-	K	-	-	-	response regulator
HAPAPPHC_03050	0.0	-	-	-	C	ko:K06871	-	ko00000	4Fe-4S single cluster domain
HAPAPPHC_03051	1.09e-246	-	-	-	S	-	-	-	radical SAM domain protein
HAPAPPHC_03052	6.92e-281	-	-	-	CO	-	-	-	amine dehydrogenase activity
HAPAPPHC_03053	1.03e-15	-	-	-	KT	-	-	-	Lanthionine synthetase C-like protein
HAPAPPHC_03054	2.32e-261	-	-	-	M	-	-	-	Glycosyl transferases group 1
HAPAPPHC_03055	0.0	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HAPAPPHC_03056	2.74e-286	-	-	-	CO	-	-	-	amine dehydrogenase activity
HAPAPPHC_03057	3.31e-64	-	-	-	M	-	-	-	Glycosyl transferase, family 2
HAPAPPHC_03058	3.51e-293	-	-	-	CO	-	-	-	amine dehydrogenase activity
HAPAPPHC_03059	1.74e-156	-	-	-	CO	-	-	-	amine dehydrogenase activity
HAPAPPHC_03060	2.25e-54	-	-	-	CO	-	-	-	amine dehydrogenase activity
HAPAPPHC_03061	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	hmm pf03412
HAPAPPHC_03062	7.15e-65	-	-	-	V	ko:K06147	-	ko00000,ko02000	hmm pf03412
HAPAPPHC_03063	0.0	-	-	-	C	ko:K06871	-	ko00000	4Fe-4S single cluster domain
HAPAPPHC_03065	3.78e-217	-	-	-	P	-	-	-	transport
HAPAPPHC_03066	1.11e-299	-	-	-	V	ko:K02022	-	ko00000	HlyD family secretion protein
HAPAPPHC_03067	1.74e-291	nagC	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HAPAPPHC_03068	6.62e-231	nanA	4.1.3.3, 4.2.1.41, 4.3.3.7	-	EM	ko:K01639,ko:K01707,ko:K01714	ko00053,ko00261,ko00300,ko00520,ko01100,ko01110,ko01120,ko01130,ko01230,map00053,map00261,map00300,map00520,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the DapA family
HAPAPPHC_03069	4.73e-313	nanE	5.1.3.8	-	G	ko:K01787	ko00520,map00520	ko00000,ko00001,ko01000	N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
HAPAPPHC_03070	7.29e-307	-	-	-	G	ko:K08191	-	ko00000,ko02000	Major Facilitator Superfamily
HAPAPPHC_03071	6.46e-85	-	-	-	P	-	-	-	TonB dependent receptor
HAPAPPHC_03072	0.0	-	-	-	P	-	-	-	TonB dependent receptor
HAPAPPHC_03073	0.0	-	-	-	GM	ko:K21572	-	ko00000,ko02000	Pfam:SusD
HAPAPPHC_03074	0.0	nanH	3.2.1.18	GH33	G	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	ko00000,ko00001,ko01000,ko02042	N-terminal domain of BNR-repeat neuraminidase
HAPAPPHC_03075	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 20, catalytic domain protein
HAPAPPHC_03076	0.0	estS	3.1.1.53	-	E	ko:K05970	-	ko00000,ko01000	Carbohydrate esterase, sialic acid-specific acetylesterase
HAPAPPHC_03077	1.67e-295	-	-	-	S	-	-	-	Cyclically-permuted mutarotase family protein
HAPAPPHC_03079	1.46e-140	-	-	-	T	-	-	-	Cyclic nucleotide-binding domain
HAPAPPHC_03080	2.64e-305	-	2.3.1.29	-	E	ko:K00639	ko00260,map00260	ko00000,ko00001,ko01000,ko01007	2-amino-3-ketobutyrate CoA ligase
HAPAPPHC_03081	9.06e-184	-	-	-	-	-	-	-	-
HAPAPPHC_03082	2.35e-267	-	-	-	M	ko:K11031	ko02024,map02024	ko00000,ko00001,ko02042	Thiol-activated cytolysin
HAPAPPHC_03083	0.0	fmo	-	-	S	ko:K11031	ko02024,map02024	ko00000,ko00001,ko02042	Thiol-activated cytolysin
HAPAPPHC_03084	2.06e-200	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
HAPAPPHC_03085	2.01e-141	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
HAPAPPHC_03086	1.25e-186	-	-	-	L	-	-	-	Protein of unknown function (DUF2400)
HAPAPPHC_03087	1.96e-170	-	-	-	L	-	-	-	DNA alkylation repair
HAPAPPHC_03088	1.33e-228	-	1.1.1.26	-	CH	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HAPAPPHC_03089	2.17e-36	spmA	-	-	S	ko:K06373	-	ko00000	membrane
HAPAPPHC_03090	2.76e-232	spmA	-	-	S	ko:K06373	-	ko00000	membrane
HAPAPPHC_03091	3.02e-101	ybeY	-	-	S	-	-	-	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HAPAPPHC_03092	3.16e-190	-	-	-	S	-	-	-	KilA-N domain
HAPAPPHC_03094	5.28e-152	-	-	-	M	-	-	-	Outer membrane protein beta-barrel domain
HAPAPPHC_03095	3.88e-287	-	-	-	T	-	-	-	Calcineurin-like phosphoesterase
HAPAPPHC_03096	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HAPAPPHC_03097	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Adenine deaminase C-terminal domain
HAPAPPHC_03098	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HAPAPPHC_03099	2.85e-103	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HAPAPPHC_03100	3.81e-73	ypjD	-	-	S	-	-	-	MazG nucleotide pyrophosphohydrolase domain
HAPAPPHC_03101	3.33e-214	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HAPAPPHC_03102	2.43e-223	ispB	2.5.1.90	-	H	ko:K02523	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HAPAPPHC_03103	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HAPAPPHC_03104	1.05e-209	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HAPAPPHC_03105	4.79e-272	araJ	-	-	EGP	ko:K08156	-	ko00000,ko02000	Major Facilitator Superfamily
HAPAPPHC_03106	1.71e-262	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HAPAPPHC_03107	1.15e-235	tolB3	-	-	U	-	-	-	WD40-like Beta Propeller Repeat
HAPAPPHC_03108	2.02e-268	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HAPAPPHC_03109	1.57e-233	-	-	-	S	-	-	-	Fimbrillin-like
HAPAPPHC_03110	1.49e-223	-	-	-	S	-	-	-	Fimbrillin-like
HAPAPPHC_03111	1.89e-97	-	-	-	S	-	-	-	Domain of unknown function (DUF4252)
HAPAPPHC_03112	1.58e-112	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70, region 4
HAPAPPHC_03113	1.23e-83	-	-	-	-	-	-	-	-
HAPAPPHC_03114	1.04e-101	-	-	-	S	-	-	-	Domain of unknown function (DUF4252)
HAPAPPHC_03115	2.17e-287	-	-	-	S	-	-	-	6-bladed beta-propeller
HAPAPPHC_03116	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HAPAPPHC_03117	1.24e-153	tal	2.2.1.2	-	F	ko:K00616,ko:K08314	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HAPAPPHC_03118	1.64e-284	-	-	-	-	-	-	-	-
HAPAPPHC_03119	3.95e-311	-	2.1.1.37	-	H	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	C-5 cytosine-specific DNA methylase
HAPAPPHC_03120	5.23e-06	-	-	-	-	-	-	-	-
HAPAPPHC_03123	3.91e-253	-	-	-	-	-	-	-	-
HAPAPPHC_03125	1.36e-46	-	-	-	S	-	-	-	Tetratricopeptide repeat
HAPAPPHC_03126	4.62e-38	-	-	-	S	-	-	-	Tetratricopeptide repeat
HAPAPPHC_03127	1.39e-162	-	-	-	S	-	-	-	Tetratricopeptide repeat
HAPAPPHC_03128	2.1e-123	-	-	-	S	-	-	-	ORF6N domain
HAPAPPHC_03129	4.25e-122	-	-	-	S	-	-	-	ORF6N domain
HAPAPPHC_03130	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
HAPAPPHC_03131	4.14e-198	-	-	-	S	-	-	-	membrane
HAPAPPHC_03132	3.77e-138	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HAPAPPHC_03133	0.0	-	-	-	T	-	-	-	Two component regulator propeller
HAPAPPHC_03134	6.49e-251	-	-	-	I	-	-	-	Acyltransferase family
HAPAPPHC_03135	0.0	-	-	-	P	-	-	-	TonB-dependent receptor
HAPAPPHC_03136	5.73e-239	nadA	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HAPAPPHC_03138	1.1e-124	spoU	-	-	J	-	-	-	RNA methyltransferase
HAPAPPHC_03139	7.07e-131	-	-	-	S	-	-	-	Domain of unknown function (DUF4294)
HAPAPPHC_03140	3.75e-138	dinD	-	-	S	ko:K14623	-	ko00000,ko03400	DNA-damage-inducible protein D
HAPAPPHC_03141	1.33e-187	-	-	-	-	-	-	-	-
HAPAPPHC_03142	0.0	-	-	-	L	-	-	-	Psort location OuterMembrane, score
HAPAPPHC_03143	2.81e-184	-	-	-	C	-	-	-	radical SAM domain protein
HAPAPPHC_03144	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 2 family
HAPAPPHC_03145	2.89e-151	-	-	-	S	-	-	-	ORF6N domain
HAPAPPHC_03146	6.05e-177	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HAPAPPHC_03147	6.79e-59	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HAPAPPHC_03149	4.5e-185	-	-	-	S	-	-	-	Tetratricopeptide repeat
HAPAPPHC_03151	0.0	-	-	-	-	-	-	-	-
HAPAPPHC_03152	6.99e-51	-	-	-	S	-	-	-	Domain of unknown function (DUF5025)
HAPAPPHC_03155	0.0	-	-	-	S	-	-	-	PA14
HAPAPPHC_03156	0.0	sulP	-	-	P	ko:K03321	-	ko00000,ko02000	Sulfate permease
HAPAPPHC_03157	3.19e-126	rbr	-	-	C	-	-	-	Rubrerythrin
HAPAPPHC_03158	0.0	nadB	1.4.3.16	-	H	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of L-aspartate to iminoaspartate
HAPAPPHC_03159	2.78e-268	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HAPAPPHC_03160	9.52e-117	-	-	-	GM	ko:K21572	-	ko00000,ko02000	SusD family
HAPAPPHC_03161	7.04e-26	-	-	-	PT	-	-	-	Domain of unknown function (DUF4974)
HAPAPPHC_03162	1.99e-49	-	-	-	K	ko:K03088	-	ko00000,ko03021	RNA polymerase sigma-70 factor
HAPAPPHC_03163	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HAPAPPHC_03164	0.0	-	-	-	P	ko:K21572	-	ko00000,ko02000	SusD family
HAPAPPHC_03165	2.32e-313	-	-	-	V	-	-	-	Multidrug transporter MatE
HAPAPPHC_03166	3.44e-14	-	-	-	S	-	-	-	Tetratricopeptide repeat
HAPAPPHC_03168	1.07e-46	-	-	-	M	-	-	-	glycosyl transferase family 2
HAPAPPHC_03169	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
HAPAPPHC_03170	3.96e-219	-	-	-	M	-	-	-	glycosyl transferase family 2
HAPAPPHC_03171	8.14e-265	-	-	-	M	-	-	-	Chaperone of endosialidase
HAPAPPHC_03173	0.0	-	-	-	M	-	-	-	RHS repeat-associated core domain protein
HAPAPPHC_03176	2.04e-121	-	-	-	M	-	-	-	RHS repeat-associated core domain protein
HAPAPPHC_03177	3.18e-17	-	-	-	-	-	-	-	-
HAPAPPHC_03179	4.31e-122	-	-	-	S	-	-	-	PQQ-like domain
HAPAPPHC_03180	1.17e-120	-	-	-	-	-	-	-	-
HAPAPPHC_03181	3.91e-91	-	-	-	S	-	-	-	Bacterial PH domain
HAPAPPHC_03182	2.15e-152	lpdA	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dihydrolipoyl dehydrogenase
HAPAPPHC_03183	2.4e-154	lpdA	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dihydrolipoyl dehydrogenase
HAPAPPHC_03184	6.1e-170	-	-	-	S	-	-	-	Domain of unknown function (DUF4271)
HAPAPPHC_03185	6.61e-180	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
HAPAPPHC_03186	1.06e-83	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HAPAPPHC_03187	1.13e-48	yidD	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
HAPAPPHC_03188	1.05e-158	-	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
HAPAPPHC_03189	9.87e-307	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HAPAPPHC_03192	7.05e-216	bglA	-	-	G	-	-	-	Glycoside Hydrolase
HAPAPPHC_03193	0.0	-	-	-	S	-	-	-	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HAPAPPHC_03194	6.9e-216	-	-	-	S	-	-	-	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HAPAPPHC_03195	0.0	-	-	-	P	-	-	-	Carboxypeptidase regulatory-like domain
HAPAPPHC_03196	2.02e-300	-	-	-	S	ko:K21572	-	ko00000,ko02000	Pfam:SusD
HAPAPPHC_03197	0.0	-	-	-	S	-	-	-	Putative glucoamylase
HAPAPPHC_03198	0.0	-	-	-	G	-	-	-	F5 8 type C domain
HAPAPPHC_03199	0.0	-	-	-	S	-	-	-	Putative glucoamylase
HAPAPPHC_03200	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Fibronectin type III-like domain
HAPAPPHC_03201	5.91e-40	bglX	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	PFAM Glycosyl hydrolase family 3 C terminal domain
HAPAPPHC_03202	0.0	bglX	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	PFAM Glycosyl hydrolase family 3 C terminal domain
HAPAPPHC_03203	0.0	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
HAPAPPHC_03204	6.23e-61	-	-	-	S	-	-	-	Protein of unknown function (DUF2442)
HAPAPPHC_03205	6.15e-195	-	-	-	S	-	-	-	Phospholipase/Carboxylesterase
HAPAPPHC_03207	1.35e-207	-	-	-	S	-	-	-	membrane
HAPAPPHC_03208	2.27e-54	-	-	-	S	ko:K07263	-	ko00000,ko01000,ko01002	Belongs to the peptidase M16 family
HAPAPPHC_03209	0.0	-	-	-	S	ko:K07263	-	ko00000,ko01000,ko01002	Belongs to the peptidase M16 family
HAPAPPHC_03210	6.23e-51	-	-	-	S	-	-	-	Divergent 4Fe-4S mono-cluster
HAPAPPHC_03211	1.77e-66	-	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
HAPAPPHC_03212	0.0	-	-	-	EG	-	-	-	Protein of unknown function (DUF2723)
HAPAPPHC_03213	4.51e-143	pgdA_1	-	-	G	-	-	-	polysaccharide deacetylase
HAPAPPHC_03214	4.53e-224	queG	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HAPAPPHC_03215	0.0	-	-	-	S	-	-	-	PS-10 peptidase S37
HAPAPPHC_03216	3.7e-202	mntA	-	-	P	ko:K09815,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Zinc-uptake complex component A periplasmic
HAPAPPHC_03217	4.85e-182	znuC	-	-	P	ko:K09817	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HAPAPPHC_03218	2.78e-22	znuC	-	-	P	ko:K09817	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HAPAPPHC_03219	2.11e-249	-	5.1.3.2	-	GM	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	NAD dependent epimerase dehydratase family protein
HAPAPPHC_03220	3.34e-175	-	-	-	S	-	-	-	Putative auto-transporter adhesin, head GIN domain
HAPAPPHC_03221	3.11e-26	-	-	-	S	-	-	-	Putative auto-transporter adhesin, head GIN domain
HAPAPPHC_03222	5.02e-184	-	-	-	S	-	-	-	Putative auto-transporter adhesin, head GIN domain
HAPAPPHC_03224	5.39e-146	-	-	-	S	-	-	-	Putative auto-transporter adhesin, head GIN domain
HAPAPPHC_03225	3.13e-112	-	-	-	S	-	-	-	Putative auto-transporter adhesin, head GIN domain
HAPAPPHC_03226	2.39e-113	-	-	-	S	ko:K07005	-	ko00000	Pfam:Pyridox_oxidase
HAPAPPHC_03227	3.17e-303	-	-	-	M	-	-	-	Linear amide C-N hydrolases, choloylglycine hydrolase family
HAPAPPHC_03228	1.25e-290	-	-	-	S	-	-	-	6-bladed beta-propeller
HAPAPPHC_03229	9.18e-242	-	-	-	S	-	-	-	TolB-like 6-blade propeller-like
HAPAPPHC_03230	5.26e-216	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Serine acetyltransferase
HAPAPPHC_03231	0.0	rlmL	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
HAPAPPHC_03232	0.0	pepX2	3.4.14.12, 3.4.14.5	-	E	ko:K01278,ko:K18574	ko04974,map04974	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	Peptidase, S9A B C family, catalytic domain protein
HAPAPPHC_03233	8.16e-303	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
HAPAPPHC_03234	8.55e-246	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HAPAPPHC_03235	4.38e-102	-	-	-	S	-	-	-	SNARE associated Golgi protein
HAPAPPHC_03236	8.67e-294	-	-	-	S	-	-	-	Polysaccharide biosynthesis protein
HAPAPPHC_03237	2.6e-258	argE	3.5.1.16	-	E	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related
HAPAPPHC_03238	1.74e-222	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HAPAPPHC_03239	0.0	-	-	-	T	-	-	-	Y_Y_Y domain
HAPAPPHC_03240	0.0	-	3.2.1.177	GH31	G	ko:K01811	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 31 family
HAPAPPHC_03241	0.0	bga	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
HAPAPPHC_03242	0.0	bglB_4	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	hydrolase, family 3
HAPAPPHC_03243	1.98e-233	yfeX	-	-	P	ko:K07223	-	ko00000	Dyp-type peroxidase family
HAPAPPHC_03244	5.31e-210	-	-	-	-	-	-	-	-
HAPAPPHC_03245	5.97e-119	-	-	-	K	ko:K03088	-	ko00000,ko03021	RNA polymerase
HAPAPPHC_03246	3.76e-41	-	-	-	S	-	-	-	Protein of unknown function (DUF1573)
HAPAPPHC_03247	6.82e-54	-	-	-	S	-	-	-	Protein of unknown function (DUF1573)
HAPAPPHC_03249	4.66e-99	-	-	-	S	-	-	-	Domain of unknown function (DUF4221)
HAPAPPHC_03251	1.14e-283	-	-	-	E	-	-	-	non supervised orthologous group
HAPAPPHC_03252	6.28e-227	-	-	-	PT	-	-	-	Domain of unknown function (DUF4974)
HAPAPPHC_03253	0.0	-	-	-	P	-	-	-	TonB dependent receptor
HAPAPPHC_03254	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	SusD family
HAPAPPHC_03255	3.89e-206	-	-	-	S	-	-	-	Endonuclease exonuclease phosphatase family
HAPAPPHC_03256	5.19e-223	-	-	-	S	-	-	-	Endonuclease/Exonuclease/phosphatase family
HAPAPPHC_03257	4.36e-123	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70, region 4
HAPAPPHC_03258	4.22e-220	-	-	-	PT	-	-	-	Domain of unknown function (DUF4974)
HAPAPPHC_03259	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HAPAPPHC_03260	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	SusD family
HAPAPPHC_03261	0.0	-	-	-	-	-	-	-	-
HAPAPPHC_03262	0.0	-	-	-	S	-	-	-	Domain of Unknown Function with PDB structure (DUF3863)
HAPAPPHC_03263	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 2 family
HAPAPPHC_03264	0.0	-	-	-	G	-	-	-	Glycosyl hydrolases family 2, TIM barrel domain
HAPAPPHC_03266	1.52e-263	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
HAPAPPHC_03267	2.86e-286	-	-	-	S	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
HAPAPPHC_03268	5.88e-128	-	-	-	K	ko:K03088	-	ko00000,ko03021	RNA polymerase sigma-70 factor
HAPAPPHC_03269	8.57e-219	-	-	-	PT	-	-	-	Sigma factor regulatory protein, FecR PupR family
HAPAPPHC_03270	0.0	-	-	-	H	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HAPAPPHC_03271	0.0	-	-	-	F	ko:K21572	-	ko00000,ko02000	SusD family
HAPAPPHC_03272	0.0	-	-	-	G	-	-	-	alpha-L-rhamnosidase
HAPAPPHC_03273	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 2, sugar binding domain protein
HAPAPPHC_03274	0.0	-	-	-	S	-	-	-	protein conserved in bacteria
HAPAPPHC_03275	2.82e-187	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HAPAPPHC_03276	4.37e-128	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70, region 4
HAPAPPHC_03277	4.73e-229	-	-	-	PT	-	-	-	Domain of unknown function (DUF4974)
HAPAPPHC_03278	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HAPAPPHC_03279	0.0	-	-	-	F	ko:K21572	-	ko00000,ko02000	SusD family
HAPAPPHC_03281	6.59e-227	-	-	-	L	-	-	-	COG NOG11942 non supervised orthologous group
HAPAPPHC_03282	1.15e-24	-	-	-	S	-	-	-	Domain of unknown function (DUF4469) with IG-like fold
HAPAPPHC_03283	0.0	-	-	-	S	-	-	-	regulation of response to stimulus
HAPAPPHC_03284	1.85e-71	-	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase C-terminal domain
HAPAPPHC_03285	0.0	-	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase C-terminal domain
HAPAPPHC_03286	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 92
HAPAPPHC_03287	3.87e-288	-	3.2.1.197	-	G	ko:K21065	-	ko00000,ko01000	Pfam:DUF377
HAPAPPHC_03288	0.0	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HAPAPPHC_03289	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 92
HAPAPPHC_03290	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 92
HAPAPPHC_03291	1.12e-206	-	3.1.2.12	CE1	S	ko:K01070	ko00680,ko01120,ko01200,map00680,map01120,map01200	ko00000,ko00001,ko01000	Putative esterase
HAPAPPHC_03292	8.73e-79	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HAPAPPHC_03293	1.32e-186	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HAPAPPHC_03294	1.7e-92	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HAPAPPHC_03295	9.25e-178	znuB	-	-	P	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family protein
HAPAPPHC_03296	0.0	-	-	-	M	-	-	-	Membrane
HAPAPPHC_03297	1.53e-210	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Metallopeptidase family M24
HAPAPPHC_03298	8e-230	-	-	-	S	-	-	-	AI-2E family transporter
HAPAPPHC_03299	4.55e-286	-	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HAPAPPHC_03300	0.0	-	-	-	M	-	-	-	Peptidase family S41
HAPAPPHC_03301	0.0	-	-	-	P	ko:K03324	-	ko00000,ko02000	Na Pi-cotransporter II-like protein
HAPAPPHC_03302	0.0	udk2	2.7.1.48	-	FJ	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	ATPase (AAA
HAPAPPHC_03303	0.0	-	-	-	S	-	-	-	Predicted AAA-ATPase
HAPAPPHC_03304	0.0	-	-	-	T	-	-	-	Tetratricopeptide repeat protein
HAPAPPHC_03307	1.64e-180	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
HAPAPPHC_03308	1.47e-121	-	-	-	KT	ko:K02477	-	ko00000,ko02022	phosphorelay signal transduction system
HAPAPPHC_03309	1.35e-78	-	-	-	-	-	-	-	-
HAPAPPHC_03310	1.8e-24	-	-	-	-	-	-	-	-
HAPAPPHC_03311	1.15e-156	-	-	-	KT	-	-	-	Lanthionine synthetase C-like protein
HAPAPPHC_03313	0.0	-	-	-	C	ko:K06871	-	ko00000	Radical SAM domain protein
HAPAPPHC_03314	8.9e-311	-	-	-	S	-	-	-	radical SAM domain protein
HAPAPPHC_03315	2.92e-300	-	-	-	S	-	-	-	6-bladed beta-propeller
HAPAPPHC_03316	1.22e-310	-	-	-	M	-	-	-	Glycosyltransferase Family 4
HAPAPPHC_03317	2.39e-108	-	-	-	V	ko:K06147	-	ko00000,ko02000	hmm pf03412
HAPAPPHC_03318	4.34e-138	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HAPAPPHC_03319	6.14e-279	-	-	-	L	ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
HAPAPPHC_03320	1.66e-138	-	-	-	S	-	-	-	GAD-like domain
HAPAPPHC_03321	3.24e-63	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HAPAPPHC_03322	6.32e-86	-	-	-	-	-	-	-	-
HAPAPPHC_03323	1.81e-78	-	-	-	-	-	-	-	-
HAPAPPHC_03324	1.35e-102	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.46
HAPAPPHC_03325	2.52e-202	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HAPAPPHC_03326	3.92e-216	-	-	-	S	-	-	-	RteC protein
HAPAPPHC_03327	1.05e-92	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HAPAPPHC_03328	0.0	-	-	-	L	-	-	-	AAA domain
HAPAPPHC_03329	2.52e-119	-	-	-	H	-	-	-	RibD C-terminal domain
HAPAPPHC_03330	4.64e-288	-	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	COG0550 Topoisomerase IA
HAPAPPHC_03331	1.57e-179	-	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	COG0550 Topoisomerase IA
HAPAPPHC_03332	5.45e-189	-	-	-	S	-	-	-	COG NOG09947 non supervised orthologous group
HAPAPPHC_03333	1.66e-91	-	-	-	S	-	-	-	COG NOG09947 non supervised orthologous group
HAPAPPHC_03335	1.58e-45	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HAPAPPHC_03336	2.52e-148	-	-	-	T	-	-	-	COG COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
HAPAPPHC_03337	2.16e-98	-	-	-	-	-	-	-	-
HAPAPPHC_03338	1.47e-41	-	-	-	-	-	-	-	-
HAPAPPHC_03340	4.14e-164	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HAPAPPHC_03341	1.16e-243	-	-	-	S	-	-	-	Nucleotidyl transferase AbiEii toxin, Type IV TA system
HAPAPPHC_03342	0.0	-	-	-	U	-	-	-	COG COG3505 Type IV secretory pathway, VirD4 components
HAPAPPHC_03343	3.99e-284	-	-	-	U	-	-	-	Relaxase mobilization nuclease domain protein
HAPAPPHC_03344	1.63e-95	-	-	-	-	-	-	-	-
HAPAPPHC_03345	6.12e-184	-	-	-	D	-	-	-	COG NOG26689 non supervised orthologous group
HAPAPPHC_03346	5.79e-88	-	-	-	S	-	-	-	Protein of unknown function (DUF3408)
HAPAPPHC_03347	1.17e-143	-	-	-	S	-	-	-	COG NOG24967 non supervised orthologous group
HAPAPPHC_03348	2.97e-41	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HAPAPPHC_03349	0.0	-	2.7.7.49	-	H	ko:K00986	-	ko00000,ko01000	Group II intron, maturase-specific domain
HAPAPPHC_03350	8.31e-06	traG	-	-	U	-	-	-	Conjugation system ATPase, TraG family
HAPAPPHC_03351	2.38e-72	-	-	-	S	-	-	-	Domain of unknown function (DUF4133)
HAPAPPHC_03352	0.0	-	-	-	U	-	-	-	Conjugation system ATPase, TraG family
HAPAPPHC_03353	1.7e-81	-	-	-	S	-	-	-	Domain of unknown function, B. Theta Gene description (DUF3876)
HAPAPPHC_03354	2.33e-136	-	-	-	U	-	-	-	COG NOG09946 non supervised orthologous group
HAPAPPHC_03355	2.01e-220	-	-	-	S	-	-	-	Conjugative transposon TraJ protein
HAPAPPHC_03356	5.29e-145	traK	-	-	U	-	-	-	Conjugative transposon TraK protein
HAPAPPHC_03357	4.73e-66	-	-	-	S	-	-	-	COG NOG30268 non supervised orthologous group
HAPAPPHC_03358	1.21e-302	traM	-	-	S	-	-	-	Conjugative transposon TraM protein
HAPAPPHC_03359	2.57e-222	-	-	-	U	-	-	-	Conjugative transposon TraN protein
HAPAPPHC_03360	1.08e-137	-	-	-	S	-	-	-	COG NOG19079 non supervised orthologous group
HAPAPPHC_03361	2.23e-105	-	-	-	S	-	-	-	Domain of unknown function, B. Theta Gene description (DUF3872)
HAPAPPHC_03362	1.71e-74	-	-	-	-	-	-	-	-
HAPAPPHC_03363	1.03e-118	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HAPAPPHC_03364	3.37e-50	-	-	-	S	-	-	-	Domain of unknown function, B. Theta Gene description (DUF3873)
HAPAPPHC_03365	9.12e-35	-	-	-	-	-	-	-	-
HAPAPPHC_03366	1.91e-130	-	-	-	S	-	-	-	Antirestriction protein (ArdA)
HAPAPPHC_03367	3.67e-114	-	-	-	S	-	-	-	ORF6N domain
HAPAPPHC_03368	2.3e-295	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HAPAPPHC_03369	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	hmm pf03412
HAPAPPHC_03370	8.65e-293	-	-	-	V	ko:K02022	-	ko00000	HlyD family secretion protein
HAPAPPHC_03371	0.0	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	RNA polymerase sigma54 factor
HAPAPPHC_03372	4.63e-113	-	-	-	I	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HAPAPPHC_03373	4.51e-84	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
HAPAPPHC_03374	2.94e-107	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HAPAPPHC_03375	0.0	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HAPAPPHC_03376	8.62e-102	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
HAPAPPHC_03377	0.0	-	-	-	NU	-	-	-	Tetratricopeptide repeat
HAPAPPHC_03378	2.34e-203	-	-	-	S	-	-	-	Domain of unknown function (DUF4292)
HAPAPPHC_03379	1.01e-279	yibP	-	-	D	-	-	-	peptidase
HAPAPPHC_03380	1.87e-215	-	-	-	S	-	-	-	PHP domain protein
HAPAPPHC_03381	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 63 C-terminal domain
HAPAPPHC_03382	6.17e-284	phoA	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Alkaline phosphatase homologues
HAPAPPHC_03383	0.0	-	-	-	G	-	-	-	Fn3 associated
HAPAPPHC_03384	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	Pfam:SusD
HAPAPPHC_03385	0.0	-	-	-	P	-	-	-	TonB dependent receptor
HAPAPPHC_03387	0.0	uxaC	5.3.1.12	-	G	ko:K01812	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Glucuronate isomerase
HAPAPPHC_03388	1.02e-164	eda	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	KDPG and KHG aldolase
HAPAPPHC_03389	1.05e-255	-	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	pfkB family carbohydrate kinase
HAPAPPHC_03390	4.01e-235	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HAPAPPHC_03391	9.48e-300	prtC	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	collagenase
HAPAPPHC_03392	5.29e-95	-	-	-	S	ko:K07107	-	ko00000,ko01000	acyl-CoA thioester hydrolase, YbgC YbaW family
HAPAPPHC_03393	6.46e-265	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
HAPAPPHC_03396	9.01e-257	-	-	-	M	-	-	-	peptidase S41
HAPAPPHC_03397	2.73e-206	-	-	-	S	-	-	-	Protein of unknown function (DUF3316)
HAPAPPHC_03398	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Belongs to the type II topoisomerase GyrA ParC subunit family
HAPAPPHC_03399	1.18e-22	-	-	-	S	-	-	-	Outer membrane protein beta-barrel domain
HAPAPPHC_03400	4.1e-154	-	-	-	S	-	-	-	Outer membrane protein beta-barrel domain
HAPAPPHC_03402	0.0	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HAPAPPHC_03403	0.0	glyQS	6.1.1.14	-	J	ko:K01880	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of glycine to tRNA(Gly)
HAPAPPHC_03404	7.83e-123	-	5.2.1.8	-	M	ko:K01802,ko:K03773	-	ko00000,ko01000,ko03110	Peptidyl-prolyl cis-trans isomerase
HAPAPPHC_03405	1.61e-181	-	-	-	KT	-	-	-	LytTr DNA-binding domain
HAPAPPHC_03406	2.23e-182	-	-	-	S	-	-	-	Cell wall-active antibiotics response 4TMS YvqF
HAPAPPHC_03407	0.0	-	-	-	T	-	-	-	Psort location CytoplasmicMembrane, score
HAPAPPHC_03408	0.0	-	-	-	T	-	-	-	Psort location CytoplasmicMembrane, score
HAPAPPHC_03409	7.03e-311	-	-	-	CG	-	-	-	glycosyl
HAPAPPHC_03410	5.69e-302	-	-	-	S	-	-	-	Radical SAM superfamily
HAPAPPHC_03411	5.27e-185	frdB	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
HAPAPPHC_03412	4.87e-187	sdhA	1.3.5.1, 1.3.5.4	-	C	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	SdhA B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC D which are the membrane components and form cytochrome b556
HAPAPPHC_03413	1.36e-259	sdhA	1.3.5.1, 1.3.5.4	-	C	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	SdhA B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC D which are the membrane components and form cytochrome b556
HAPAPPHC_03414	1.28e-161	sdhC	-	-	S	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002	fumarate reductase
HAPAPPHC_03415	6.1e-36	-	-	-	T	-	-	-	Tetratricopeptide repeat protein
HAPAPPHC_03416	3.84e-201	-	-	-	S	-	-	-	Domain of unknown function (DUF4934)
HAPAPPHC_03417	2.46e-76	-	-	-	S	-	-	-	Domain of unknown function (DUF4934)
HAPAPPHC_03418	1.22e-108	-	-	-	M	-	-	-	Gram-negative bacterial TonB protein C-terminal
HAPAPPHC_03419	3.95e-82	-	-	-	K	-	-	-	Transcriptional regulator
HAPAPPHC_03420	0.0	-	-	-	KMT	-	-	-	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HAPAPPHC_03421	8.94e-239	-	-	-	S	-	-	-	Tetratricopeptide repeats
HAPAPPHC_03422	5.68e-282	-	-	-	S	-	-	-	6-bladed beta-propeller
HAPAPPHC_03423	0.0	-	-	-	M	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
HAPAPPHC_03424	4.18e-168	-	-	-	S	-	-	-	Conserved hypothetical protein (DUF2461)
HAPAPPHC_03425	1.7e-281	-	-	-	S	-	-	-	Biotin-protein ligase, N terminal
HAPAPPHC_03426	6.34e-297	-	-	-	S	-	-	-	Domain of unknown function (DUF4842)
HAPAPPHC_03427	5.97e-96	-	-	-	S	-	-	-	Family of unknown function (DUF3836)
HAPAPPHC_03428	0.0	trpB	4.2.1.20	-	E	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HAPAPPHC_03429	7.27e-308	-	-	-	-	-	-	-	-
HAPAPPHC_03430	5.5e-192	-	-	-	-	-	-	-	-
HAPAPPHC_03431	1.13e-98	-	-	-	-	-	-	-	-
HAPAPPHC_03432	4.73e-242	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HAPAPPHC_03433	0.0	-	-	-	S	-	-	-	Lamin Tail Domain
HAPAPPHC_03434	2.01e-194	-	-	-	S	-	-	-	Lamin Tail Domain
HAPAPPHC_03436	6.75e-224	-	-	-	Q	-	-	-	Clostripain family
HAPAPPHC_03437	9.77e-26	-	-	-	Q	-	-	-	Clostripain family
HAPAPPHC_03438	8.64e-136	-	-	-	M	-	-	-	non supervised orthologous group
HAPAPPHC_03439	3.83e-113	-	-	-	M	-	-	-	Domain of unknown function, B. Theta Gene description (DUF3868)
HAPAPPHC_03440	2.51e-109	-	-	-	S	-	-	-	AAA ATPase domain
HAPAPPHC_03441	1.24e-163	-	-	-	S	-	-	-	DJ-1/PfpI family
HAPAPPHC_03442	5.11e-163	yfkO	-	-	C	-	-	-	nitroreductase
HAPAPPHC_03444	7.52e-63	-	-	-	S	-	-	-	COG NOG31846 non supervised orthologous group
HAPAPPHC_03445	7.09e-240	-	-	-	S	-	-	-	Domain of unknown function (DUF5119)
HAPAPPHC_03447	1.87e-215	-	-	-	K	-	-	-	transcriptional regulator (AraC family)
HAPAPPHC_03448	0.0	-	-	-	S	-	-	-	Glycosyl hydrolase-like 10
HAPAPPHC_03449	0.0	uvrA1	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HAPAPPHC_03450	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	SusD family
HAPAPPHC_03451	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HAPAPPHC_03452	2.57e-44	-	-	-	-	-	-	-	-
HAPAPPHC_03453	7.37e-132	-	-	-	M	-	-	-	sodium ion export across plasma membrane
HAPAPPHC_03454	6.17e-281	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HAPAPPHC_03455	1.41e-201	-	-	-	G	-	-	-	Domain of unknown function (DUF4954)
HAPAPPHC_03456	1.33e-271	-	-	-	G	-	-	-	Domain of unknown function (DUF4954)
HAPAPPHC_03457	8.89e-214	-	-	-	K	-	-	-	transcriptional regulator (AraC family)
HAPAPPHC_03458	1.18e-137	-	5.3.1.9	-	G	ko:K06859	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucose-6-phosphate isomerase (GPI)
HAPAPPHC_03459	2.17e-189	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HAPAPPHC_03460	5.97e-201	-	5.3.1.9	-	G	ko:K06859	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucose-6-phosphate isomerase (GPI)
HAPAPPHC_03461	0.0	araE	-	-	P	ko:K02100	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HAPAPPHC_03462	8.01e-20	-	-	-	S	-	-	-	Sugar-binding cellulase-like
HAPAPPHC_03463	8.3e-184	-	-	-	S	-	-	-	Sugar-binding cellulase-like
HAPAPPHC_03464	0.0	lacZ_17	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
HAPAPPHC_03465	7.7e-85	lacZ_17	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
HAPAPPHC_03466	0.0	-	-	-	P	-	-	-	TonB-dependent receptor plug domain
HAPAPPHC_03467	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	SusD family
HAPAPPHC_03468	6.41e-205	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HAPAPPHC_03469	5.54e-212	xerC	-	-	D	ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
HAPAPPHC_03470	6.93e-96	aroQ	4.2.1.10	-	E	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a trans-dehydration via an enolate intermediate
HAPAPPHC_03471	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
HAPAPPHC_03472	4.02e-151	-	2.1.1.104	-	S	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	ko00000,ko00001,ko00002,ko01000	O-Methyltransferase
HAPAPPHC_03473	2.67e-69	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HAPAPPHC_03474	2.96e-264	lolE	-	-	M	ko:K09808,ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Efflux ABC transporter, permease protein
HAPAPPHC_03475	1.02e-255	manC	2.7.7.13	-	M	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	ko00000,ko00001,ko00002,ko01000	mannose-1-phosphate guanylyltransferase
HAPAPPHC_03478	8.71e-91	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HAPAPPHC_03479	6.68e-195	cypM_2	-	-	Q	-	-	-	Nodulation protein S (NodS)
HAPAPPHC_03480	1.15e-195	yafP	-	-	K	ko:K03830	-	ko00000,ko01000	Protein of unknown function (DUF3795)
HAPAPPHC_03481	2.92e-195	-	-	-	S	-	-	-	Protein of unknown function (DUF1016)
HAPAPPHC_03482	1.15e-150	-	-	-	L	-	-	-	Phage integrase SAM-like domain
HAPAPPHC_03484	7.59e-12	-	-	-	-	-	-	-	-
HAPAPPHC_03485	8.51e-272	-	-	-	I	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HAPAPPHC_03486	1.16e-148	cat	2.3.1.28	-	V	ko:K19271	-	br01600,ko00000,ko01000,ko01504	Chloramphenicol acetyltransferase
HAPAPPHC_03487	6.23e-123	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.96
HAPAPPHC_03488	6.88e-41	-	-	-	S	-	-	-	Carbon-nitrogen hydrolase
HAPAPPHC_03489	6.18e-158	-	-	-	S	-	-	-	Carbon-nitrogen hydrolase
HAPAPPHC_03490	1.5e-277	-	-	-	S	ko:K07148	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
HAPAPPHC_03491	3.74e-87	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HAPAPPHC_03492	3.02e-236	gldN	-	-	S	-	-	-	Gliding motility-associated protein GldN
HAPAPPHC_03493	0.0	gldM	-	-	S	-	-	-	Gliding motility-associated protein GldM
HAPAPPHC_03494	1.04e-178	gldL	-	-	S	-	-	-	Gliding motility-associated protein, GldL
HAPAPPHC_03495	0.0	gldK	-	-	M	-	-	-	gliding motility-associated lipoprotein GldK
HAPAPPHC_03496	1.18e-205	-	-	-	P	-	-	-	membrane
HAPAPPHC_03497	1.61e-48	-	-	-	S	-	-	-	Protein of unknown function (DUF2795)
HAPAPPHC_03498	3.65e-133	yvqK	2.5.1.17	-	S	ko:K00798	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	adenosyltransferase
HAPAPPHC_03499	4.15e-188	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HAPAPPHC_03500	5.67e-313	tolC	-	-	MU	-	-	-	Outer membrane efflux protein
HAPAPPHC_03501	0.0	bepE_4	-	-	V	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HAPAPPHC_03502	7.13e-150	bepE_4	-	-	V	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HAPAPPHC_03503	1.54e-249	-	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HAPAPPHC_03504	0.0	-	-	-	E	-	-	-	Transglutaminase-like superfamily
HAPAPPHC_03505	0.0	cvrA	-	-	P	ko:K11105	-	ko00000,ko02000	Potassium
HAPAPPHC_03506	0.0	-	-	-	S	-	-	-	Beta-L-arabinofuranosidase, GH127
HAPAPPHC_03507	0.0	-	-	-	S	ko:K09955	-	ko00000	Beta-L-arabinofuranosidase, GH127
HAPAPPHC_03508	3.09e-194	-	-	-	M	ko:K21572	-	ko00000,ko02000	RagB SusD domain protein
HAPAPPHC_03509	5.99e-49	-	-	-	H	-	-	-	TonB dependent receptor
HAPAPPHC_03510	0.0	-	-	-	H	-	-	-	TonB dependent receptor
HAPAPPHC_03511	4.23e-165	-	-	-	PT	-	-	-	Domain of unknown function (DUF4974)
HAPAPPHC_03512	6.87e-101	-	-	-	K	ko:K03088	-	ko00000,ko03021	RNA polymerase sigma-70 factor
HAPAPPHC_03513	1.38e-183	-	-	-	G	-	-	-	Glycogen debranching enzyme
HAPAPPHC_03514	4.11e-161	-	-	-	F	ko:K21572	-	ko00000,ko02000	RagB SusD domain protein
HAPAPPHC_03515	1.9e-276	-	-	-	P	-	-	-	TonB dependent receptor
HAPAPPHC_03517	1.09e-167	-	-	-	PT	-	-	-	Domain of unknown function (DUF4974)
HAPAPPHC_03518	2.44e-94	-	-	-	K	ko:K03088	-	ko00000,ko03021	RNA polymerase sigma-70 factor
HAPAPPHC_03519	0.0	-	-	-	T	-	-	-	PglZ domain
HAPAPPHC_03520	2.95e-42	-	-	-	S	ko:K07075	-	ko00000	Nucleotidyltransferase domain
HAPAPPHC_03521	6.03e-36	-	-	-	S	-	-	-	Protein of unknown function DUF86
HAPAPPHC_03522	6.4e-97	yjeE	-	-	S	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
HAPAPPHC_03523	8.56e-34	-	-	-	S	-	-	-	Immunity protein 17
HAPAPPHC_03524	0.0	rnr	-	-	J	ko:K12573,ko:K12585	ko03018,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HAPAPPHC_03525	2.65e-234	-	-	-	G	ko:K14274	ko00040,map00040	ko00000,ko00001,ko01000	SMP-30/Gluconolaconase/LRE-like region
HAPAPPHC_03526	1.1e-278	yghO	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.96
HAPAPPHC_03527	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	DNA topoisomerase (ATP-hydrolyzing)
HAPAPPHC_03528	7.73e-109	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HAPAPPHC_03529	6.49e-216	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
HAPAPPHC_03530	2.12e-119	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
HAPAPPHC_03531	1.1e-119	-	-	-	P	ko:K07240	-	ko00000,ko02000	Chromate transporter
HAPAPPHC_03532	1.33e-124	-	-	-	P	ko:K07240	-	ko00000,ko02000	Chromate transporter
HAPAPPHC_03533	1.25e-300	-	-	-	MU	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	Outer membrane efflux protein
HAPAPPHC_03534	3.11e-272	-	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HAPAPPHC_03535	2.11e-168	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HAPAPPHC_03536	5.03e-277	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HAPAPPHC_03537	6.14e-259	cheA	-	-	T	-	-	-	Histidine kinase
HAPAPPHC_03538	5.84e-173	yehT_1	-	-	KT	-	-	-	LytTr DNA-binding domain
HAPAPPHC_03539	0.0	dacB	3.4.16.4	-	M	ko:K07259	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
HAPAPPHC_03540	2.38e-258	-	-	-	S	-	-	-	Permease
HAPAPPHC_03542	1.76e-273	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HAPAPPHC_03543	8.42e-124	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HAPAPPHC_03544	3.49e-63	-	-	-	S	-	-	-	MerR HTH family regulatory protein
HAPAPPHC_03545	2.76e-60	-	-	-	S	-	-	-	Domain of unknown function, B. Theta Gene description (DUF3876)
HAPAPPHC_03546	1.27e-66	-	-	-	K	-	-	-	Helix-turn-helix domain
HAPAPPHC_03547	1.42e-170	-	-	-	K	-	-	-	COG NOG38984 non supervised orthologous group
HAPAPPHC_03548	1.15e-131	-	-	-	S	-	-	-	COG NOG23385 non supervised orthologous group
HAPAPPHC_03549	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	COG COG3973 Superfamily I DNA and RNA helicases
HAPAPPHC_03551	2.12e-89	-	-	-	K	-	-	-	acetyltransferase
HAPAPPHC_03552	3.42e-161	-	-	-	V	-	-	-	COG0534 Na -driven multidrug efflux pump
HAPAPPHC_03553	7.01e-137	-	-	-	S	ko:K18234	-	ko00000,ko01000,ko01504	Bacterial transferase hexapeptide repeat protein
HAPAPPHC_03554	6.41e-101	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
HAPAPPHC_03555	4.69e-75	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
HAPAPPHC_03556	8.67e-279	int	-	-	L	-	-	-	Phage integrase SAM-like domain
HAPAPPHC_03557	6.43e-203	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HAPAPPHC_03558	1.58e-83	-	-	-	K	-	-	-	COG NOG37763 non supervised orthologous group
HAPAPPHC_03559	7.54e-265	-	-	-	KT	-	-	-	Homeodomain-like domain
HAPAPPHC_03560	2.8e-279	-	-	-	L	-	-	-	COG NOG08810 non supervised orthologous group
HAPAPPHC_03561	0.0	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
HAPAPPHC_03562	1.05e-226	per1	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	COG2367 Beta-lactamase class A
HAPAPPHC_03563	0.0	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
HAPAPPHC_03564	1.29e-44	-	-	-	-	-	-	-	-
HAPAPPHC_03565	8.7e-91	-	-	-	-	-	-	-	-
HAPAPPHC_03566	7.4e-71	-	-	-	S	-	-	-	Helix-turn-helix domain
HAPAPPHC_03567	1.84e-125	-	-	-	-	-	-	-	-
HAPAPPHC_03568	2.09e-181	-	-	-	-	-	-	-	-
HAPAPPHC_03569	7.17e-61	-	-	-	-	-	-	-	-
HAPAPPHC_03570	7.51e-05	-	-	-	S	-	-	-	Putative phage abortive infection protein
HAPAPPHC_03573	0.0	-	-	-	P	ko:K03455	-	ko00000	COG0475 Kef-type K transport systems, membrane components
HAPAPPHC_03574	1.07e-281	-	-	-	G	-	-	-	Major Facilitator Superfamily
HAPAPPHC_03575	2.46e-218	-	-	-	G	-	-	-	pfkB family carbohydrate kinase
HAPAPPHC_03576	1.39e-18	-	-	-	-	-	-	-	-
HAPAPPHC_03577	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2339)
HAPAPPHC_03578	7.99e-312	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HAPAPPHC_03579	2.61e-199	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydropteroate synthase
HAPAPPHC_03580	9.29e-179	dacA	-	-	S	-	-	-	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HAPAPPHC_03581	6.47e-227	pta	2.3.1.8	-	C	ko:K00625,ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Phosphotransacetylase
HAPAPPHC_03582	2.99e-291	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HAPAPPHC_03583	4.28e-163	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HAPAPPHC_03584	0.0	-	-	-	T	-	-	-	Periplasmic binding proteins and sugar binding domain of LacI family
HAPAPPHC_03585	0.0	sacC	3.2.1.80	-	G	ko:K03332	ko00051,map00051	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
HAPAPPHC_03586	1.59e-210	-	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family
HAPAPPHC_03587	1.3e-263	-	-	-	G	-	-	-	Major Facilitator
HAPAPPHC_03588	2.98e-123	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HAPAPPHC_03589	1.18e-222	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HAPAPPHC_03590	0.0	dgt	3.1.5.1	-	F	ko:K01129	ko00230,map00230	ko00000,ko00001,ko01000	Dehydrogenase
HAPAPPHC_03591	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HAPAPPHC_03592	0.0	-	-	-	H	-	-	-	Susd and RagB outer membrane lipoprotein
HAPAPPHC_03593	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 2 family
HAPAPPHC_03594	2.01e-141	yciO	-	-	J	-	-	-	Belongs to the SUA5 family
HAPAPPHC_03595	9.13e-203	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
HAPAPPHC_03596	0.0	alr	5.1.1.1, 6.3.2.10	-	M	ko:K01775,ko:K01929	ko00300,ko00473,ko00550,ko01100,ko01502,map00300,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HAPAPPHC_03597	6.15e-234	-	-	-	E	-	-	-	GSCFA family
HAPAPPHC_03598	4.19e-198	-	-	-	S	-	-	-	Peptidase of plants and bacteria
HAPAPPHC_03599	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 92
HAPAPPHC_03600	2.11e-209	-	-	-	G	-	-	-	Glycosyl hydrolase family 92
HAPAPPHC_03601	0.0	-	-	-	M	ko:K21572	-	ko00000,ko02000	SusD family
HAPAPPHC_03602	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HAPAPPHC_03603	0.0	-	-	-	T	-	-	-	Response regulator receiver domain protein
HAPAPPHC_03604	1.84e-232	-	-	-	T	-	-	-	COG0642 Signal transduction histidine kinase
HAPAPPHC_03605	3.05e-93	-	-	-	T	-	-	-	COG0642 Signal transduction histidine kinase
HAPAPPHC_03606	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 9.97
HAPAPPHC_03607	6.36e-59	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 9.97
HAPAPPHC_03608	6.52e-130	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 9.97
HAPAPPHC_03609	1.7e-182	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HAPAPPHC_03610	1.2e-130	-	-	-	T	-	-	-	Cyclic nucleotide-binding domain protein
HAPAPPHC_03611	6.78e-308	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HAPAPPHC_03612	2.47e-136	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	alkyl hydroperoxide reductase
HAPAPPHC_03613	0.0	ahpF	-	-	C	ko:K03387	-	ko00000,ko01000	NADH dehydrogenase
HAPAPPHC_03614	3.18e-77	-	-	-	-	-	-	-	-
HAPAPPHC_03615	0.0	-	-	-	P	ko:K16089	-	ko00000,ko02000	TonB-dependent receptor
HAPAPPHC_03616	9.62e-248	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
HAPAPPHC_03617	0.0	-	-	-	H	-	-	-	TonB-dependent Receptor Plug Domain
HAPAPPHC_03618	0.0	-	-	-	E	-	-	-	Domain of unknown function (DUF4374)
HAPAPPHC_03619	2.07e-199	-	-	-	S	ko:K07017	-	ko00000	Putative esterase
HAPAPPHC_03620	5.79e-270	piuB	-	-	S	-	-	-	PepSY-associated TM region
HAPAPPHC_03621	1.05e-82	-	-	-	C	ko:K03839	-	ko00000	Low-potential electron donor to a number of redox enzymes
HAPAPPHC_03622	2.5e-52	-	-	-	T	-	-	-	Domain of unknown function (DUF5074)
HAPAPPHC_03623	3.61e-99	-	-	-	T	-	-	-	Domain of unknown function (DUF5074)
HAPAPPHC_03624	2.46e-118	-	3.1.3.97	-	S	ko:K07053	-	ko00000,ko01000	Domain of unknown function
HAPAPPHC_03625	5.08e-50	-	-	-	T	-	-	-	Domain of unknown function (DUF5074)
HAPAPPHC_03626	1.43e-150	-	-	-	T	-	-	-	Domain of unknown function (DUF5074)
HAPAPPHC_03627	4.06e-43	-	-	-	T	-	-	-	Domain of unknown function (DUF5074)
HAPAPPHC_03628	7.1e-63	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HAPAPPHC_03629	0.0	-	-	-	H	-	-	-	COG NOG08812 non supervised orthologous group
HAPAPPHC_03630	1.38e-37	-	-	-	S	-	-	-	Peptidase M4, propeptide, PepSY
HAPAPPHC_03631	3.07e-130	-	-	-	P	ko:K02014	-	ko00000,ko02000	COGs COG4773 Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid
HAPAPPHC_03632	3.27e-295	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HAPAPPHC_03633	1.99e-203	-	-	-	T	-	-	-	Domain of unknown function (DUF5074)
HAPAPPHC_03634	2.74e-186	-	-	-	S	-	-	-	COG NOG23387 non supervised orthologous group
HAPAPPHC_03635	5.03e-202	-	-	-	S	-	-	-	amine dehydrogenase activity
HAPAPPHC_03636	9.44e-304	-	-	-	H	-	-	-	TonB-dependent receptor
HAPAPPHC_03637	3.22e-119	nrdG	1.97.1.4	-	C	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HAPAPPHC_03638	0.0	nrdD	1.1.98.6	-	FK	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
HAPAPPHC_03639	0.0	-	-	-	P	ko:K16089	-	ko00000,ko02000	TonB dependent receptor
HAPAPPHC_03640	2.67e-223	-	4.99.1.3	-	H	ko:K02190	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	CbiX
HAPAPPHC_03641	2.56e-272	-	4.99.1.3	-	H	ko:K02190	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Cobalt chelatase (CbiK)
HAPAPPHC_03642	0.0	-	-	-	P	ko:K16089	-	ko00000,ko02000	TonB-dependent receptor
HAPAPPHC_03643	1.23e-181	-	-	-	O	ko:K05801	-	ko00000,ko03110	Tellurite resistance protein TerB
HAPAPPHC_03645	1.11e-145	-	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HAPAPPHC_03646	2.92e-135	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HAPAPPHC_03647	0.0	accC	6.3.4.14, 6.4.1.2, 6.4.1.3	-	I	ko:K01961,ko:K01965	ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase
HAPAPPHC_03648	8.57e-84	-	6.4.1.1	-	I	ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Biotin-requiring enzyme
HAPAPPHC_03649	1.93e-101	-	2.1.3.15, 6.4.1.3	-	I	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Carboxyl transferase domain
HAPAPPHC_03650	4.31e-206	-	2.1.3.15, 6.4.1.3	-	I	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Carboxyl transferase domain
HAPAPPHC_03652	4.19e-09	-	-	-	-	-	-	-	-
HAPAPPHC_03653	0.0	-	-	-	P	ko:K07085	-	ko00000	TrkA C-terminal domain protein
HAPAPPHC_03654	0.0	-	-	-	H	-	-	-	TonB-dependent receptor
HAPAPPHC_03655	0.0	-	-	-	S	-	-	-	amine dehydrogenase activity
HAPAPPHC_03656	4.55e-265	-	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
HAPAPPHC_03657	3.24e-28	-	-	-	C	ko:K18930	-	ko00000	FAD linked oxidases, C-terminal domain
HAPAPPHC_03658	0.0	-	-	-	C	ko:K18930	-	ko00000	FAD linked oxidases, C-terminal domain
HAPAPPHC_03659	0.0	-	1.8.5.4	-	S	ko:K17218	ko00920,map00920	ko00000,ko00001,ko01000	Pyridine nucleotide-disulphide oxidoreductase
HAPAPPHC_03661	2.59e-278	-	-	-	S	-	-	-	6-bladed beta-propeller
HAPAPPHC_03663	0.0	-	-	-	M	-	-	-	helix_turn_helix, Lux Regulon
HAPAPPHC_03664	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase large chain, oligomerisation domain
HAPAPPHC_03665	0.0	-	-	-	O	-	-	-	Subtilase family
HAPAPPHC_03666	4.74e-148	-	-	-	O	-	-	-	Subtilase family
HAPAPPHC_03668	1.98e-77	-	-	-	H	-	-	-	COG NOG08812 non supervised orthologous group
HAPAPPHC_03669	5.75e-270	-	-	-	H	-	-	-	COG NOG08812 non supervised orthologous group
HAPAPPHC_03670	2.05e-83	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HAPAPPHC_03671	0.0	-	-	-	S	-	-	-	PFAM Uncharacterised BCR, COG1649
HAPAPPHC_03672	0.0	-	-	-	V	-	-	-	AcrB/AcrD/AcrF family
HAPAPPHC_03673	0.0	-	-	-	MU	-	-	-	Outer membrane efflux protein
HAPAPPHC_03674	4.07e-317	-	-	-	V	-	-	-	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HAPAPPHC_03675	0.0	-	-	-	V	-	-	-	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HAPAPPHC_03676	3.35e-247	-	-	-	M	-	-	-	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HAPAPPHC_03677	0.0	-	-	-	M	-	-	-	O-Antigen ligase
HAPAPPHC_03678	1.67e-251	-	-	-	E	-	-	-	non supervised orthologous group
HAPAPPHC_03679	1.25e-84	-	-	-	E	-	-	-	non supervised orthologous group
HAPAPPHC_03680	2.7e-217	-	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HAPAPPHC_03681	4.51e-263	-	-	-	S	-	-	-	TolB-like 6-blade propeller-like
HAPAPPHC_03682	1.23e-11	-	-	-	S	-	-	-	NVEALA protein
HAPAPPHC_03683	1.87e-160	-	-	-	S	-	-	-	Protein of unknown function (DUF1573)
HAPAPPHC_03684	1.15e-260	-	-	-	S	-	-	-	TolB-like 6-blade propeller-like
HAPAPPHC_03686	7.22e-191	-	-	-	K	-	-	-	Transcriptional regulator
HAPAPPHC_03687	5.46e-280	-	-	-	S	-	-	-	Domain of unknown function (DUF4221)
HAPAPPHC_03688	1.96e-78	-	-	-	-	-	-	-	-
HAPAPPHC_03689	1.15e-210	-	-	-	EG	-	-	-	EamA-like transporter family
HAPAPPHC_03690	2.15e-54	-	-	-	S	-	-	-	PAAR motif
HAPAPPHC_03691	1.14e-256	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Tryptophanyl-tRNA synthetase
HAPAPPHC_03692	1.68e-97	-	-	-	K	ko:K03088	-	ko00000,ko03021	RNA polymerase sigma-70 factor
HAPAPPHC_03693	8.13e-198	-	-	-	S	-	-	-	Outer membrane protein beta-barrel domain
HAPAPPHC_03695	1.62e-194	-	-	-	PT	-	-	-	Domain of unknown function (DUF4974)
HAPAPPHC_03696	0.0	-	-	-	P	-	-	-	TonB-dependent receptor plug domain
HAPAPPHC_03697	1.68e-253	-	-	-	S	-	-	-	Domain of unknown function (DUF4249)
HAPAPPHC_03698	0.0	-	-	-	P	-	-	-	TonB-dependent receptor plug domain
HAPAPPHC_03699	1.74e-273	-	-	-	S	-	-	-	Domain of unknown function (DUF4249)
HAPAPPHC_03700	1.24e-104	-	-	-	-	-	-	-	-
HAPAPPHC_03701	8.79e-118	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70, region 4
HAPAPPHC_03702	0.0	-	-	-	S	-	-	-	Outer membrane protein beta-barrel domain
HAPAPPHC_03703	0.0	-	-	-	S	-	-	-	LVIVD repeat
HAPAPPHC_03704	0.0	-	-	-	P	-	-	-	TonB-dependent Receptor Plug Domain
HAPAPPHC_03705	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	Pfam:SusD
HAPAPPHC_03706	0.0	-	-	-	E	-	-	-	Zinc carboxypeptidase
HAPAPPHC_03707	5.41e-135	-	-	-	M	-	-	-	Linear amide C-N hydrolases, choloylglycine hydrolase family
HAPAPPHC_03708	2.49e-81	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HAPAPPHC_03709	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HAPAPPHC_03710	4.11e-106	-	-	-	T	-	-	-	COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains
HAPAPPHC_03711	1.08e-205	-	-	-	T	-	-	-	Histidine kinase-like ATPases
HAPAPPHC_03714	0.0	-	-	-	E	-	-	-	Prolyl oligopeptidase family
HAPAPPHC_03716	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA-directed DNA polymerase
HAPAPPHC_03717	2.54e-71	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HAPAPPHC_03718	1.76e-156	mnmC	-	-	S	-	-	-	S-adenosyl-L-methionine-dependent methyltransferase
HAPAPPHC_03719	0.0	-	-	-	P	-	-	-	Carboxypeptidase regulatory-like domain
HAPAPPHC_03720	0.0	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
HAPAPPHC_03721	1.88e-227	zraS_1	-	-	T	-	-	-	GHKL domain
HAPAPPHC_03722	0.0	-	-	-	T	-	-	-	Sigma-54 interaction domain
HAPAPPHC_03724	5.95e-194	nudC	3.6.1.22	-	L	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	ko00000,ko00001,ko01000	NADH pyrophosphatase zinc ribbon domain
HAPAPPHC_03725	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Efflux ABC transporter, permease protein
HAPAPPHC_03726	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HAPAPPHC_03727	6.58e-103	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HAPAPPHC_03728	2.3e-134	-	-	-	P	-	-	-	TonB-dependent receptor
HAPAPPHC_03729	0.0	-	-	-	P	-	-	-	TonB-dependent receptor
HAPAPPHC_03730	5.19e-230	-	-	-	S	-	-	-	AAA domain
HAPAPPHC_03731	1.26e-113	-	-	-	-	-	-	-	-
HAPAPPHC_03732	2e-17	-	-	-	-	-	-	-	-
HAPAPPHC_03733	7.84e-19	-	-	-	-	-	-	-	-
HAPAPPHC_03734	1.53e-151	-	-	-	M	-	-	-	Outer membrane protein beta-barrel domain
HAPAPPHC_03735	6.97e-109	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HAPAPPHC_03736	7.16e-82	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
HAPAPPHC_03737	4.62e-188	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
HAPAPPHC_03738	6.54e-225	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HAPAPPHC_03739	2.96e-285	aspC	2.6.1.1	-	E	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
HAPAPPHC_03740	6.52e-82	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HAPAPPHC_03741	1.83e-176	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HAPAPPHC_03742	0.0	-	-	-	S	ko:K07091	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Permease, YjgP YjgQ family
HAPAPPHC_03743	7.47e-88	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HAPAPPHC_03745	2.24e-211	-	-	-	S	-	-	-	Fimbrillin-A associated anchor proteins Mfa1 and Mfa2
HAPAPPHC_03746	0.0	-	-	-	T	-	-	-	cheY-homologous receiver domain
HAPAPPHC_03747	7.85e-298	-	-	-	S	-	-	-	Major fimbrial subunit protein (FimA)
HAPAPPHC_03749	5.99e-282	-	-	-	S	-	-	-	Major fimbrial subunit protein (FimA)
HAPAPPHC_03750	1.74e-58	-	-	-	S	-	-	-	double-stranded DNA endodeoxyribonuclease activity
HAPAPPHC_03751	6.21e-28	-	-	-	L	-	-	-	Arm DNA-binding domain
HAPAPPHC_03752	1.52e-26	-	-	-	-	-	-	-	-
HAPAPPHC_03753	2.96e-208	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HAPAPPHC_03754	1.62e-37	-	-	-	L	-	-	-	Arm DNA-binding domain
HAPAPPHC_03755	2.1e-64	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
HAPAPPHC_03756	3.36e-19	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HAPAPPHC_03757	3.73e-48	-	-	-	-	-	-	-	-
HAPAPPHC_03758	1.39e-128	mgsA	4.2.3.3	-	G	ko:K01734	ko00640,ko01120,map00640,map01120	ko00000,ko00001,ko01000	methylglyoxal synthase
HAPAPPHC_03759	1.7e-200	-	-	-	E	-	-	-	Belongs to the arginase family
HAPAPPHC_03760	5.92e-103	glgP	2.4.1.1, 2.4.1.11, 2.4.1.8	GH65,GT3,GT35	G	ko:K00688,ko:K00691,ko:K16153	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000,ko01003	Protein of unknown function (DUF3417)
HAPAPPHC_03761	0.0	glgP	2.4.1.1, 2.4.1.11, 2.4.1.8	GH65,GT3,GT35	G	ko:K00688,ko:K00691,ko:K16153	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000,ko01003	Protein of unknown function (DUF3417)
HAPAPPHC_03762	0.0	-	-	-	P	ko:K03455	-	ko00000	PTS system, fructose-specific IIABC component K02768 K02769
HAPAPPHC_03763	4.15e-232	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HAPAPPHC_03764	2.27e-114	-	-	-	K	ko:K03088	-	ko00000,ko03021	DNA-directed RNA polymerase sigma subunit PrtI (ECF sigma factor) K00960
HAPAPPHC_03765	2.78e-88	hsp20	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HAPAPPHC_03766	5.48e-186	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HAPAPPHC_03767	3.84e-259	fbaB	4.1.2.13	-	G	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	COG COG1830 DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes
HAPAPPHC_03768	9.33e-109	ftnA	1.16.3.2	-	P	ko:K02217	-	ko00000,ko01000	Iron-storage protein
HAPAPPHC_03769	6.2e-146	-	-	-	U	ko:K05595	-	ko00000,ko02000	UPF0056 membrane protein
HAPAPPHC_03770	2.28e-101	-	1.16.3.2	-	P	ko:K02217	-	ko00000,ko01000	Iron-storage protein
HAPAPPHC_03771	1.93e-34	-	-	-	-	-	-	-	-
HAPAPPHC_03772	1.56e-74	-	-	-	-	-	-	-	-
HAPAPPHC_03775	1.41e-59	-	-	-	S	-	-	-	COG NOG30576 non supervised orthologous group
HAPAPPHC_03776	1.47e-91	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.96
HAPAPPHC_03777	7.27e-151	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HAPAPPHC_03778	3.08e-08	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HAPAPPHC_03779	9.84e-30	-	-	-	-	-	-	-	-
HAPAPPHC_03781	1.04e-228	-	-	-	L	-	-	-	Arm DNA-binding domain
HAPAPPHC_03782	3.46e-303	-	-	-	S	-	-	-	Major fimbrial subunit protein (FimA)
HAPAPPHC_03783	6.82e-08	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HAPAPPHC_03784	5.53e-97	-	-	-	S	-	-	-	Major fimbrial subunit protein (FimA)
HAPAPPHC_03788	9.73e-111	-	-	-	-	-	-	-	-
HAPAPPHC_03789	1.89e-57	-	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	regulation of translation
HAPAPPHC_03790	6.85e-137	-	-	-	M	-	-	-	Protein of unknown function (DUF3575)
HAPAPPHC_03791	0.0	-	-	-	M	-	-	-	Domain of unknown function, B. Theta Gene description (DUF3868)
HAPAPPHC_03793	4.34e-159	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Thiamin pyrophosphokinase, catalytic domain
HAPAPPHC_03794	1.82e-119	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
HAPAPPHC_03795	0.0	-	-	-	P	ko:K02014	-	ko00000,ko02000	TonB-dependent Receptor Plug Domain
HAPAPPHC_03797	7.72e-99	rimP	-	-	S	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
HAPAPPHC_03798	5.21e-189	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HAPAPPHC_03799	2.46e-88	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HAPAPPHC_03800	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HAPAPPHC_03801	4.07e-107	-	-	-	S	ko:K03558	-	ko00000	Colicin V production protein
HAPAPPHC_03802	0.0	sufB	-	-	O	ko:K09014	-	ko00000	Cysteine desulfurase
HAPAPPHC_03803	3.59e-18	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	Part of SUF system involved in inserting iron-sulfur clusters into proteins
HAPAPPHC_03804	1.72e-146	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	Part of SUF system involved in inserting iron-sulfur clusters into proteins
HAPAPPHC_03805	3.96e-291	sufD	-	-	O	ko:K09015	-	ko00000	FeS assembly protein SufD
HAPAPPHC_03806	5.7e-198	gloA	4.4.1.5	-	E	ko:K01759,ko:K03827	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HAPAPPHC_03807	0.0	-	3.2.1.135	GH13	G	ko:K21575	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 13 family
HAPAPPHC_03808	0.0	-	-	-	G	-	-	-	Domain of unknown function (DUF5110)
HAPAPPHC_03809	0.0	-	3.1.6.1	-	P	ko:K01130	ko00140,ko00600,map00140,map00600	ko00000,ko00001,ko01000	Sulfatase
HAPAPPHC_03810	1.81e-294	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HAPAPPHC_03811	2.8e-76	fjo27	-	-	S	-	-	-	VanZ like family
HAPAPPHC_03812	2.35e-144	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HAPAPPHC_03813	2.91e-94	sufE	-	-	S	ko:K02426	-	ko00000	Fe-S metabolism
HAPAPPHC_03814	8.19e-244	-	-	-	S	-	-	-	Glutamine cyclotransferase
HAPAPPHC_03815	0.0	-	3.4.13.19	-	E	ko:K01273,ko:K01274	-	ko00000,ko00537,ko01000,ko01002,ko04147	Membrane dipeptidase (Peptidase family M19)
HAPAPPHC_03816	2.03e-35	-	3.4.13.19	-	E	ko:K01273,ko:K01274	-	ko00000,ko00537,ko01000,ko01002,ko04147	Membrane dipeptidase (Peptidase family M19)
HAPAPPHC_03817	0.0	-	3.4.13.19	-	E	ko:K01273,ko:K01274	-	ko00000,ko00537,ko01000,ko01002,ko04147	Membrane dipeptidase (Peptidase family M19)
HAPAPPHC_03818	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HAPAPPHC_03820	8.63e-49	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
HAPAPPHC_03822	7.86e-82	-	-	-	S	-	-	-	Protein of unknown function (DUF2721)
HAPAPPHC_03823	7.56e-157	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
HAPAPPHC_03825	9.3e-104	-	-	-	-	-	-	-	-
HAPAPPHC_03826	1.15e-89	-	2.7.11.1	-	T	ko:K04757	-	ko00000,ko01000,ko01001,ko03021	sigma factor antagonist activity
HAPAPPHC_03827	2.03e-67	-	-	-	T	ko:K04749	-	ko00000,ko03021	STAS domain
HAPAPPHC_03828	2.16e-67	-	-	-	S	-	-	-	Fimbrillin-A associated anchor proteins Mfa1 and Mfa2
HAPAPPHC_03829	5.53e-288	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HAPAPPHC_03830	1.09e-253	-	-	-	G	-	-	-	AP endonuclease family 2 C terminus
HAPAPPHC_03831	1.32e-249	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HAPAPPHC_03832	5.12e-211	ddh	1.4.1.16	-	E	ko:K03340	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
HAPAPPHC_03833	1.32e-216	lgt	-	-	M	-	-	-	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HAPAPPHC_03834	4.81e-296	fprA	1.6.3.4	-	C	ko:K22405	-	ko00000,ko01000	Metallo-beta-lactamase domain protein
HAPAPPHC_03835	2.52e-197	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HAPAPPHC_03836	0.0	-	-	-	E	-	-	-	Prolyl oligopeptidase family
HAPAPPHC_03837	0.0	-	-	-	E	ko:K21572	-	ko00000,ko02000	SusD family
HAPAPPHC_03838	0.0	-	-	-	P	-	-	-	TonB-dependent Receptor Plug Domain
HAPAPPHC_03840	2.06e-297	-	-	-	MU	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	Outer membrane efflux protein
HAPAPPHC_03841	2.56e-251	-	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HAPAPPHC_03842	3.11e-224	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, permease protein
HAPAPPHC_03843	1.8e-307	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HAPAPPHC_03844	6.3e-154	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HAPAPPHC_03845	2.82e-281	purT	2.1.2.2	-	F	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HAPAPPHC_03846	0.0	-	-	-	U	-	-	-	WD40-like Beta Propeller Repeat
HAPAPPHC_03847	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HAPAPPHC_03848	0.0	-	-	-	U	-	-	-	WD40-like Beta Propeller Repeat
HAPAPPHC_03849	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HAPAPPHC_03850	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	Pfam:SusD
HAPAPPHC_03851	0.0	-	-	-	P	-	-	-	TonB dependent receptor
HAPAPPHC_03852	0.0	-	-	-	P	-	-	-	TonB dependent receptor
HAPAPPHC_03853	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	Pfam:SusD
HAPAPPHC_03854	5.25e-175	-	-	-	S	-	-	-	Beta-lactamase superfamily domain
HAPAPPHC_03855	6.94e-92	gloA	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Lactoylglutathione lyase
HAPAPPHC_03856	1.02e-232	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	glucokinase
HAPAPPHC_03857	5.96e-127	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
HAPAPPHC_03858	0.0	-	-	-	G	-	-	-	Tetratricopeptide repeat protein
HAPAPPHC_03859	0.0	-	-	-	H	-	-	-	Psort location OuterMembrane, score
HAPAPPHC_03860	8.52e-238	-	-	-	T	-	-	-	Histidine kinase-like ATPases
HAPAPPHC_03861	1.2e-262	-	-	-	T	-	-	-	Histidine kinase-like ATPases
HAPAPPHC_03862	5.06e-199	-	-	-	T	-	-	-	GHKL domain
HAPAPPHC_03863	2.23e-278	-	3.1.3.3	-	T	ko:K07315	-	ko00000,ko01000,ko03021	Sigma factor PP2C-like phosphatases
HAPAPPHC_03866	2.65e-86	-	-	-	-	-	-	-	-
HAPAPPHC_03868	1.02e-55	-	-	-	O	-	-	-	Tetratricopeptide repeat
HAPAPPHC_03869	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HAPAPPHC_03870	3.64e-192	-	-	-	S	-	-	-	VIT family
HAPAPPHC_03871	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
HAPAPPHC_03872	4.8e-51	hupB	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HAPAPPHC_03873	3.98e-170	-	3.4.21.105	-	S	ko:K09650	-	ko00000,ko01000,ko01002,ko03029	membrane
HAPAPPHC_03874	1.2e-200	-	-	-	S	-	-	-	Rhomboid family
HAPAPPHC_03875	2.16e-264	-	-	-	S	-	-	-	Endonuclease Exonuclease phosphatase family protein
HAPAPPHC_03876	1.55e-128	-	-	-	S	-	-	-	Domain of unknown function (DUF4468) with TBP-like fold
HAPAPPHC_03877	1.33e-226	-	-	-	S	ko:K03646	-	ko00000,ko02000	Domain of unknown function (DUF4468) with TBP-like fold
HAPAPPHC_03878	0.0	secD	-	-	U	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HAPAPPHC_03879	2.38e-222	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
HAPAPPHC_03880	6.74e-268	-	-	-	K	-	-	-	Participates in transcription elongation, termination and antitermination
HAPAPPHC_03881	6.34e-90	-	-	-	-	-	-	-	-
HAPAPPHC_03882	1.3e-99	-	-	-	V	-	-	-	N-acetylmuramoyl-L-alanine amidase
HAPAPPHC_03884	5.82e-111	-	-	-	L	-	-	-	TIGRFAM DNA-binding protein, histone-like
HAPAPPHC_03885	9.24e-23	-	-	-	-	-	-	-	-
HAPAPPHC_03886	3.34e-09	-	-	-	-	-	-	-	-
HAPAPPHC_03888	0.0	wbpM	-	-	GM	-	-	-	Polysaccharide biosynthesis protein
HAPAPPHC_03889	6.43e-26	-	-	-	-	-	-	-	-
HAPAPPHC_03890	3.98e-20	-	-	-	S	-	-	-	Toxin-antitoxin system, toxin component, PIN family
HAPAPPHC_03891	9.48e-193	-	-	-	C	-	-	-	coenzyme F420-reducing hydrogenase beta subunit
HAPAPPHC_03893	1.54e-16	-	-	-	IQ	-	-	-	Phosphopantetheine attachment site
HAPAPPHC_03894	1.15e-98	-	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal
HAPAPPHC_03895	1.58e-179	-	-	-	Q	ko:K16126	ko01054,map01054	ko00000,ko00001	Non-ribosomal peptide synthetase modules and related proteins
HAPAPPHC_03896	9.25e-28	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HAPAPPHC_03897	7.74e-26	-	-	-	IQ	-	-	-	Phosphopantetheine attachment site
HAPAPPHC_03898	2.87e-128	-	-	-	S	-	-	-	Polysaccharide biosynthesis protein
HAPAPPHC_03900	3.21e-29	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HAPAPPHC_03903	0.000969	pslL	-	-	G	ko:K21005	ko02025,map02025	ko00000,ko00001	nodulation
HAPAPPHC_03904	2.39e-115	-	2.2.1.9	-	S	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	slime layer polysaccharide biosynthetic process
HAPAPPHC_03906	4.78e-29	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HAPAPPHC_03907	9e-73	-	-	-	S	-	-	-	Bacterial transferase hexapeptide (six repeats)
HAPAPPHC_03908	5.37e-29	-	-	-	IQ	-	-	-	Phosphopantetheine attachment site
HAPAPPHC_03909	1.42e-141	-	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	synthase III
HAPAPPHC_03910	1.87e-100	-	-	-	IQ	-	-	-	COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase)
HAPAPPHC_03911	1.86e-149	fabG_2	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
HAPAPPHC_03912	3.11e-294	-	-	-	IQ	-	-	-	AMP-binding enzyme
HAPAPPHC_03913	6.09e-40	-	-	-	IQ	-	-	-	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HAPAPPHC_03914	8.8e-240	-	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal
HAPAPPHC_03915	1.41e-37	-	-	-	S	-	-	-	Hexapeptide repeat of succinyl-transferase
HAPAPPHC_03916	1.27e-55	-	-	-	M	-	-	-	Bacterial sugar transferase
HAPAPPHC_03917	1.93e-80	-	-	-	C	-	-	-	WbqC-like protein family
HAPAPPHC_03918	5.87e-127	-	-	-	M	-	-	-	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HAPAPPHC_03919	1.2e-95	-	-	-	S	-	-	-	GlcNAc-PI de-N-acetylase
HAPAPPHC_03920	1.31e-308	pglE	-	-	E	-	-	-	DegT/DnrJ/EryC1/StrS aminotransferase family
HAPAPPHC_03921	2.55e-46	-	-	-	-	-	-	-	-
HAPAPPHC_03922	4.72e-93	vapC	-	-	S	ko:K18828	-	ko00000,ko01000,ko02048,ko03016	PIN domain
HAPAPPHC_03923	0.0	hutU	4.2.1.49	-	E	ko:K01712	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HAPAPPHC_03924	4.24e-216	ftcD	2.1.2.5, 4.3.1.4	-	E	ko:K00603,ko:K13990	ko00340,ko00670,ko01100,map00340,map00670,map01100	ko00000,ko00001,ko01000,ko03036,ko04147	Glutamate formiminotransferase
HAPAPPHC_03925	4.72e-303	hutI	3.5.2.7	-	Q	ko:K01468	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Imidazolone-5-propionate hydrolase
HAPAPPHC_03926	1.23e-134	fchA	-	-	E	-	-	-	Methenyltetrahydrofolate cyclohydrolase
HAPAPPHC_03927	0.0	hutH	4.3.1.3	-	E	ko:K01745	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Histidine ammonia-lyase
HAPAPPHC_03928	1.65e-289	-	-	-	S	-	-	-	Acyltransferase family
HAPAPPHC_03929	8.47e-264	mrp	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HAPAPPHC_03930	5.07e-188	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HAPAPPHC_03931	0.0	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HAPAPPHC_03935	1.05e-228	-	-	-	G	-	-	-	pfkB family carbohydrate kinase
HAPAPPHC_03936	0.0	prc	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
HAPAPPHC_03937	4.8e-285	-	-	-	S	ko:K07098	-	ko00000	Ser Thr phosphatase family protein
HAPAPPHC_03938	2.61e-260	-	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
HAPAPPHC_03939	4.8e-155	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
HAPAPPHC_03940	0.0	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
HAPAPPHC_03943	0.0	-	-	-	C	ko:K06871	-	ko00000	radical SAM domain protein
HAPAPPHC_03944	0.0	-	-	-	P	-	-	-	Outer membrane protein beta-barrel family
HAPAPPHC_03945	0.0	lktB	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HAPAPPHC_03946	0.000122	-	-	-	V	ko:K03543	-	ko00000,ko00002,ko02000	PFAM secretion protein HlyD family protein
HAPAPPHC_03947	3.98e-143	-	-	-	C	-	-	-	Nitroreductase family
HAPAPPHC_03948	1.19e-115	-	-	-	P	-	-	-	Outer membrane protein beta-barrel family
HAPAPPHC_03949	1.1e-273	-	-	-	P	-	-	-	Outer membrane protein beta-barrel family
HAPAPPHC_03950	0.0	-	-	-	P	-	-	-	Outer membrane protein beta-barrel family
HAPAPPHC_03951	9.01e-314	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HAPAPPHC_03952	4.7e-49	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HAPAPPHC_03953	0.0	-	-	-	U	-	-	-	WD40-like Beta Propeller Repeat
HAPAPPHC_03954	0.0	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	catalyzes the formation of fructose 6-phosphate from fructose-1,6-bisphosphate
HAPAPPHC_03956	4.06e-257	-	-	-	M	ko:K21572	-	ko00000,ko02000	SusD family
HAPAPPHC_03957	0.0	-	-	-	P	-	-	-	TonB dependent receptor
HAPAPPHC_03958	0.0	-	-	-	P	-	-	-	TonB dependent receptor
HAPAPPHC_03959	3.01e-235	-	-	-	M	ko:K21572	-	ko00000,ko02000	SusD family
HAPAPPHC_03960	7.09e-265	-	-	-	H	-	-	-	COG NOG08812 non supervised orthologous group
HAPAPPHC_03961	1.75e-232	-	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HAPAPPHC_03962	6.18e-238	-	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding protein
HAPAPPHC_03963	5.87e-311	-	-	-	V	-	-	-	Multidrug transporter MatE
HAPAPPHC_03964	1.53e-114	-	-	-	S	-	-	-	Domain of unknown function (DUF4251)
HAPAPPHC_03965	0.0	-	-	-	F	ko:K21572	-	ko00000,ko02000	Pfam:SusD
HAPAPPHC_03966	0.0	-	-	-	P	-	-	-	TonB dependent receptor
HAPAPPHC_03967	8.05e-88	-	-	-	O	-	-	-	Chaperonin 10 Kd subunit
HAPAPPHC_03968	3.27e-186	gltD	1.18.1.2, 1.19.1.1	-	C	ko:K00528	-	ko00000,ko01000	Ferredoxin-NADP reductase
HAPAPPHC_03969	0.0	gltA	1.3.1.1, 1.4.1.13, 1.4.1.14	-	E	ko:K00266,ko:K17722	ko00240,ko00250,ko00410,ko00770,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00240,map00250,map00410,map00770,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	catalyzes the conversion of pyrimidines to 5,6-dihydro compounds in pyrimidine degradation
HAPAPPHC_03970	6.39e-89	-	-	-	S	-	-	-	Protein of unknown function (DUF3037)
HAPAPPHC_03971	4.68e-188	-	-	-	DT	-	-	-	aminotransferase class I and II
HAPAPPHC_03975	6.85e-103	-	-	-	P	-	-	-	nitrite reductase [NAD(P)H] activity
HAPAPPHC_03976	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
HAPAPPHC_03977	1.03e-92	-	-	-	E	-	-	-	oxidoreductase activity, acting on CH-OH group of donors
HAPAPPHC_03978	1.51e-146	pyrE	2.4.2.10, 4.1.1.23	-	F	ko:K00762,ko:K13421	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HAPAPPHC_03979	3.17e-166	comF	2.4.2.14	-	S	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Phosphoribosyl transferase domain
HAPAPPHC_03980	7.17e-83	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
HAPAPPHC_03981	2.39e-226	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HAPAPPHC_03982	2.58e-253	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HAPAPPHC_03983	0.0	-	-	-	G	-	-	-	COG NOG27066 non supervised orthologous group
HAPAPPHC_03984	6.66e-175	-	-	-	M	-	-	-	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HAPAPPHC_03985	1.28e-174	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HAPAPPHC_03986	0.0	yaeT	-	-	M	ko:K07277	-	ko00000,ko02000,ko03029	membrane
HAPAPPHC_03987	4.01e-111	ompH	-	-	M	ko:K06142	-	ko00000	membrane
HAPAPPHC_03988	4.35e-98	ompH	-	-	M	ko:K06142	-	ko00000	Outer membrane protein (OmpH-like)
HAPAPPHC_03989	5.52e-204	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HAPAPPHC_03990	4.58e-82	yccF	-	-	S	-	-	-	Inner membrane component domain
HAPAPPHC_03991	0.0	-	-	-	M	-	-	-	Peptidase family M23
HAPAPPHC_03992	0.0	-	-	-	V	ko:K03327	-	ko00000,ko02000	MatE
HAPAPPHC_03993	9.25e-94	-	-	-	O	-	-	-	META domain
HAPAPPHC_03994	4.56e-104	-	-	-	O	-	-	-	META domain
HAPAPPHC_03995	0.0	-	-	-	H	ko:K02014	-	ko00000,ko02000	TonB-dependent receptor
HAPAPPHC_03996	3.13e-296	-	-	-	S	-	-	-	Protein of unknown function (DUF1343)
HAPAPPHC_03997	0.0	-	-	-	E	-	-	-	Dipeptidyl peptidase IV (DPP IV) N-terminal region
HAPAPPHC_03998	1.75e-129	-	-	-	T	ko:K06950	-	ko00000	HDIG domain protein
HAPAPPHC_03999	0.0	-	-	-	M	-	-	-	Psort location OuterMembrane, score
HAPAPPHC_04000	1.03e-165	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HAPAPPHC_04001	7.87e-238	asnA	6.3.1.1	-	E	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
HAPAPPHC_04008	1.21e-55	-	-	-	S	-	-	-	Pfam:DUF2693
HAPAPPHC_04010	1.31e-22	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.96
HAPAPPHC_04011	1.87e-117	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
HAPAPPHC_04017	1.52e-84	-	-	-	-	-	-	-	-
HAPAPPHC_04018	4.09e-204	-	-	-	T	-	-	-	AAA domain
HAPAPPHC_04020	1.68e-20	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
HAPAPPHC_04022	2.04e-207	-	-	-	L	-	-	-	viral genome integration into host DNA
HAPAPPHC_04023	3.55e-99	yjaB	-	-	K	ko:K03827	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HAPAPPHC_04024	2.27e-134	-	-	-	T	-	-	-	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HAPAPPHC_04025	4.09e-96	-	-	-	S	ko:K15977	-	ko00000	DoxX
HAPAPPHC_04029	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HAPAPPHC_04030	1.93e-259	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HAPAPPHC_04031	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
HAPAPPHC_04032	5.04e-109	asnC	-	-	K	ko:K03718	-	ko00000,ko03000	Transcriptional regulator
HAPAPPHC_04033	6.6e-129	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HAPAPPHC_04034	6.1e-101	-	-	-	U	ko:K03559	-	ko00000,ko02000	Biopolymer transporter ExbD
HAPAPPHC_04035	2.26e-136	-	-	-	U	-	-	-	Biopolymer transporter ExbD
HAPAPPHC_04036	2.3e-101	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HAPAPPHC_04037	5.76e-162	exbB	-	-	U	ko:K03561	-	ko00000,ko02000	MotA TolQ ExbB proton channel family protein
HAPAPPHC_04039	3.17e-191	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD
HAPAPPHC_04040	2.05e-230	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HAPAPPHC_04041	2.2e-107	tonB2	-	-	M	ko:K03832	-	ko00000,ko02000	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HAPAPPHC_04042	2.45e-244	porQ	-	-	I	-	-	-	penicillin-binding protein
HAPAPPHC_04043	6.6e-159	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
HAPAPPHC_04044	2.26e-210	ispH	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HAPAPPHC_04045	2.92e-231	pfkA	2.7.1.11	-	G	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HAPAPPHC_04046	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HAPAPPHC_04047	0.0	-	-	-	U	-	-	-	WD40-like Beta Propeller Repeat
HAPAPPHC_04048	3.51e-115	argK	-	-	E	ko:K07588	-	ko00000,ko01000	LAO AO transport system ATPase
HAPAPPHC_04049	1.42e-107	argK	-	-	E	ko:K07588	-	ko00000,ko01000	LAO AO transport system ATPase
HAPAPPHC_04050	4.9e-263	-	-	-	S	-	-	-	Protein of unknown function (DUF1573)
HAPAPPHC_04051	4.9e-83	-	-	-	S	-	-	-	Protein of unknown function (DUF1573)
HAPAPPHC_04052	3.38e-110	-	-	-	S	-	-	-	Alpha-2-macroglobulin family
HAPAPPHC_04053	0.0	-	-	-	S	-	-	-	Alpha-2-macroglobulin family
HAPAPPHC_04054	2.99e-119	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HAPAPPHC_04055	0.0	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
HAPAPPHC_04056	7.83e-198	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HAPAPPHC_04058	1.07e-284	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Converts alpha-aldose to the beta-anomer
HAPAPPHC_04061	1.05e-189	-	-	-	MU	ko:K03640	-	ko00000,ko02000	Belongs to the ompA family
HAPAPPHC_04062	4.59e-255	-	-	-	MU	ko:K03640	-	ko00000,ko02000	Belongs to the ompA family
HAPAPPHC_04063	3.19e-07	-	-	-	-	-	-	-	-
HAPAPPHC_04064	1.8e-34	-	-	-	S	-	-	-	ParE toxin of type II toxin-antitoxin system, parDE
HAPAPPHC_04065	7.41e-294	queA	2.4.99.17	-	H	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HAPAPPHC_04066	6.39e-259	-	-	-	L	-	-	-	Domain of unknown function (DUF2027)
HAPAPPHC_04067	1.14e-110	cyaA	4.6.1.1	-	S	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	ko00000,ko00001,ko00002,ko01000	Adenylate cyclase
HAPAPPHC_04068	8.86e-139	dpp11	-	-	E	-	-	-	peptidase S46
HAPAPPHC_04069	0.0	dpp11	-	-	E	-	-	-	peptidase S46
HAPAPPHC_04070	1.87e-26	-	-	-	-	-	-	-	-
HAPAPPHC_04071	9.21e-142	-	-	-	S	-	-	-	Zeta toxin
HAPAPPHC_04072	2.18e-276	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
HAPAPPHC_04073	0.0	fusA2	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	elongation factor G
HAPAPPHC_04074	1.02e-189	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase superfamily domain
HAPAPPHC_04075	5.01e-275	-	-	-	M	-	-	-	Glycosyl transferase family 1
HAPAPPHC_04076	0.0	metZ	2.5.1.49	-	E	ko:K01740,ko:K10764	ko00270,ko00920,ko01100,map00270,map00920,map01100	ko00000,ko00001,ko01000	O-acetylhomoserine aminocarboxypropyltransferase cysteine synthase
HAPAPPHC_04077	1.1e-312	-	-	-	V	-	-	-	Mate efflux family protein
HAPAPPHC_04078	8.93e-219	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
HAPAPPHC_04079	0.0	glnA	6.3.1.2	-	S	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	Belongs to the glutamine synthetase family
HAPAPPHC_04080	0.0	hppA	3.6.1.1	-	C	ko:K15987	ko00190,map00190	ko00000,ko00001,ko01000	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane
HAPAPPHC_04082	4.68e-197	-	-	-	S	ko:K07001	-	ko00000	Phospholipase
HAPAPPHC_04083	0.0	amyA2	-	-	G	-	-	-	Alpha amylase, catalytic domain protein
HAPAPPHC_04084	1.78e-220	pitA	-	-	P	ko:K03306	-	ko00000	Phosphate transporter family
HAPAPPHC_04085	8.45e-130	-	-	-	P	ko:K07220	-	ko00000	COG1392 Phosphate transport regulator (distant homolog of PhoU)
HAPAPPHC_04086	1.15e-145	-	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
HAPAPPHC_04088	1.34e-84	-	-	-	-	-	-	-	-
HAPAPPHC_04089	5.8e-220	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HAPAPPHC_04090	3.63e-273	trmU	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HAPAPPHC_04091	2.04e-79	-	3.4.14.4	-	S	ko:K01277	-	ko00000,ko01000,ko01002	Peptidase family M49
HAPAPPHC_04092	0.0	-	3.4.14.4	-	S	ko:K01277	-	ko00000,ko01000,ko01002	Peptidase family M49
HAPAPPHC_04093	1.69e-162	-	-	-	L	-	-	-	DNA alkylation repair enzyme
HAPAPPHC_04094	1.57e-106	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
HAPAPPHC_04095	1.01e-312	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HAPAPPHC_04096	3.96e-155	-	-	-	S	ko:K06973	-	ko00000	Putative neutral zinc metallopeptidase
HAPAPPHC_04097	0.0	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
HAPAPPHC_04098	0.0	-	3.2.1.45	GH30	G	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 30 family
HAPAPPHC_04099	2.39e-55	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HAPAPPHC_04100	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HAPAPPHC_04102	1e-73	-	-	-	S	-	-	-	COG NOG23405 non supervised orthologous group
HAPAPPHC_04103	3.97e-102	-	-	-	S	-	-	-	COG NOG28735 non supervised orthologous group
HAPAPPHC_04104	2.4e-186	mazG	3.6.1.66	-	S	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
HAPAPPHC_04105	0.0	-	1.8.1.8	-	CO	ko:K04084	-	ko00000,ko01000,ko03110	Thiol disulfide interchange protein
HAPAPPHC_04106	1.13e-217	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RluA family
HAPAPPHC_04107	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HAPAPPHC_04108	0.0	-	-	-	T	-	-	-	Psort location CytoplasmicMembrane, score
HAPAPPHC_04109	3.22e-211	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
HAPAPPHC_04110	1.38e-254	-	-	-	S	-	-	-	COG NOG26558 non supervised orthologous group
HAPAPPHC_04111	5.46e-98	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HAPAPPHC_04114	1.12e-69	-	-	-	S	-	-	-	Domain of unknown function (DUF4286)
HAPAPPHC_04115	7.39e-132	ruvC	3.1.22.4	-	L	ko:K01159	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
HAPAPPHC_04116	0.0	gdh	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HAPAPPHC_04117	0.0	ppsA	-	-	GKT	-	-	-	Pyruvate phosphate dikinase, PEP pyruvate binding domain
HAPAPPHC_04118	2.5e-261	-	-	-	S	-	-	-	endonuclease exonuclease phosphatase family protein
HAPAPPHC_04119	6.12e-88	hddC	-	-	JM	-	-	-	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon)
HAPAPPHC_04120	0.0	-	-	-	S	-	-	-	Phosphotransferase enzyme family
HAPAPPHC_04121	0.0	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HAPAPPHC_04122	7.59e-28	-	-	-	-	-	-	-	-
HAPAPPHC_04123	2.69e-82	-	-	-	S	-	-	-	Putative prokaryotic signal transducing protein
HAPAPPHC_04124	4.34e-209	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
HAPAPPHC_04125	1.05e-251	-	-	-	K	-	-	-	Participates in transcription elongation, termination and antitermination
HAPAPPHC_04126	4.01e-78	-	-	-	-	-	-	-	-
HAPAPPHC_04127	0.0	cap5D	-	-	GM	-	-	-	Polysaccharide biosynthesis protein
HAPAPPHC_04128	7.12e-292	-	-	-	S	-	-	-	InterPro IPR018631 IPR012547
HAPAPPHC_04129	6.81e-282	-	-	-	M	-	-	-	Cytidylyltransferase
HAPAPPHC_04130	2.57e-201	-	2.5.1.56	-	M	ko:K01654	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	SAF
HAPAPPHC_04132	1.87e-59	-	-	-	S	ko:K19431	-	ko00000,ko01000	polysaccharide biosynthetic process
HAPAPPHC_04135	1.68e-124	waaE	-	-	M	-	-	-	Glycosyltransferase group 2 family protein
HAPAPPHC_04137	1.07e-26	-	-	-	IQ	ko:K02078	-	ko00000,ko00001	Phosphopantetheine attachment site
HAPAPPHC_04138	2.68e-195	-	-	-	IQ	-	-	-	AMP-binding enzyme C-terminal domain
HAPAPPHC_04139	3.14e-98	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	KR domain
HAPAPPHC_04140	1e-110	-	-	-	S	-	-	-	GlcNAc-PI de-N-acetylase
HAPAPPHC_04141	4.23e-69	-	-	-	M	-	-	-	Bacterial sugar transferase
HAPAPPHC_04142	6.93e-129	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	UDP-glucose 4-epimerase activity
HAPAPPHC_04143	5.99e-48	-	-	-	G	-	-	-	Cupin 2, conserved barrel domain protein
HAPAPPHC_04145	6.57e-127	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HAPAPPHC_04146	0.0	-	-	-	P	ko:K02014	-	ko00000,ko02000	Psort location OuterMembrane, score 10.00
HAPAPPHC_04147	1.53e-128	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
HAPAPPHC_04148	3.59e-162	-	-	-	K	ko:K07322	-	ko00000	Di-iron-containing protein involved in the repair of iron-sulfur clusters
HAPAPPHC_04149	4.29e-226	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
HAPAPPHC_04150	0.0	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HAPAPPHC_04151	0.0	-	-	-	C	-	-	-	NapC/NirT cytochrome c family, N-terminal region
HAPAPPHC_04153	7.09e-132	-	-	-	K	ko:K03088	-	ko00000,ko03021	RNA polymerase sigma-70 factor
HAPAPPHC_04154	6.12e-157	-	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD-hyrolase-like
HAPAPPHC_04157	6.56e-194	eamA	-	-	EG	-	-	-	EamA-like transporter family
HAPAPPHC_04158	2.64e-94	-	-	-	K	-	-	-	helix_turn_helix ASNC type
HAPAPPHC_04159	5.46e-191	-	-	-	K	-	-	-	Helix-turn-helix domain
HAPAPPHC_04160	1.38e-82	-	-	-	S	ko:K06996	-	ko00000	Glyoxalase-like domain
HAPAPPHC_04161	1.63e-180	-	-	-	Q	-	-	-	Protein of unknown function (DUF1698)
HAPAPPHC_04162	1.2e-163	queC	6.3.4.20	-	F	ko:K06920	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HAPAPPHC_04163	1.89e-115	queF	1.7.1.13	-	H	ko:K09457	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HAPAPPHC_04164	2.16e-200	-	-	-	S	-	-	-	Domain of Unknown Function (DUF1080)
HAPAPPHC_04165	2.58e-147	-	-	-	L	-	-	-	COG COG2801 Transposase and inactivated derivatives
HAPAPPHC_04166	8.71e-52	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
HAPAPPHC_04167	1.1e-183	-	-	-	L	-	-	-	DNA metabolism protein
HAPAPPHC_04168	1.26e-304	-	-	-	S	-	-	-	Radical SAM
HAPAPPHC_04169	1.06e-105	-	-	-	PT	-	-	-	COGs COG3712 Fe2 -dicitrate sensor membrane component
HAPAPPHC_04170	0.0	-	-	-	P	-	-	-	TonB-dependent Receptor Plug
HAPAPPHC_04171	0.0	-	-	-	GM	ko:K21572	-	ko00000,ko02000	SusD family
HAPAPPHC_04172	8.31e-254	-	3.1.6.1	-	P	ko:K01130	ko00140,ko00600,map00140,map00600	ko00000,ko00001,ko01000	Arylsulfatase
HAPAPPHC_04173	0.0	-	-	-	P	-	-	-	Domain of unknown function (DUF4976)
HAPAPPHC_04174	1.23e-227	-	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
HAPAPPHC_04175	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	Psort location Cytoplasmic, score
HAPAPPHC_04176	2.31e-149	-	-	-	V	-	-	-	COG0534 Na -driven multidrug efflux pump
HAPAPPHC_04177	3.48e-07	-	-	-	S	ko:K18234	-	ko00000,ko01000,ko01504	Bacterial transferase hexapeptide (six repeats)
HAPAPPHC_04178	0.0	-	-	-	P	ko:K03316	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
HAPAPPHC_04179	0.0	-	3.2.1.3	GH15	G	ko:K01178	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolases family 15
HAPAPPHC_04180	1.35e-26	-	3.2.1.3	GH15	G	ko:K01178	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolases family 15
HAPAPPHC_04181	0.0	otsB	2.4.1.15, 3.1.3.12	GT20	G	ko:K16055	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000,ko01003	Trehalose-phosphatase
HAPAPPHC_04184	3.48e-27	-	3.4.21.53	-	T	ko:K01338	ko04112,map04112	ko00000,ko00001,ko01000,ko01002	phosphorelay signal transduction system
HAPAPPHC_04186	0.0	kdpA	3.6.3.12	-	P	ko:K01546	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
HAPAPPHC_04187	0.0	kdpB	3.6.3.12	-	P	ko:K01547	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
HAPAPPHC_04188	8.21e-133	kdpC	3.6.3.12	-	P	ko:K01548	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
HAPAPPHC_04189	7.44e-183	-	-	-	S	-	-	-	non supervised orthologous group
HAPAPPHC_04190	3.82e-153	kdpD	2.7.13.3	-	T	ko:K07646	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Osmosensitive K+ channel His kinase sensor domain
HAPAPPHC_04191	0.0	covS	-	-	T	-	-	-	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HAPAPPHC_04192	3.15e-315	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HAPAPPHC_04193	6.69e-32	-	-	-	L	-	-	-	SMART ATPase, AAA type, core
HAPAPPHC_04194	1.44e-56	-	-	-	L	-	-	-	DNA integration
HAPAPPHC_04196	2.65e-268	-	-	-	-	-	-	-	-
HAPAPPHC_04197	1.48e-248	thiL	2.7.4.16	-	H	ko:K00946	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HAPAPPHC_04198	7.9e-269	lpxK	2.7.1.130	-	F	ko:K00912	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)
HAPAPPHC_04199	0.0	sppA	-	-	OU	ko:K04773	-	ko00000,ko01000,ko01002	signal peptide peptidase SppA, 67K type
HAPAPPHC_04200	8.77e-237	-	-	-	F	-	-	-	Domain of unknown function (DUF4922)
HAPAPPHC_04201	0.0	-	-	-	M	-	-	-	Glycosyl transferase family 2
HAPAPPHC_04202	0.0	-	-	-	M	-	-	-	Fibronectin type 3 domain
HAPAPPHC_04205	1.63e-131	cobC	3.1.3.73	-	G	ko:K02226	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	phosphoglycerate mutase
HAPAPPHC_04206	2.21e-176	cobS	2.7.8.26	-	H	ko:K02233	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
HAPAPPHC_04207	1.14e-254	cobT	2.4.2.21	-	F	ko:K00768	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)
HAPAPPHC_04208	6.32e-118	cobU	2.7.1.156, 2.7.7.62	-	H	ko:K02231	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	cobinamide kinase
HAPAPPHC_04209	4.73e-121	-	5.4.99.21	-	J	ko:K06182	-	ko00000,ko01000,ko03009	S4 domain protein
HAPAPPHC_04210	5.43e-228	cobD	6.3.1.10	-	H	ko:K02227	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
HAPAPPHC_04211	7.53e-113	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70, region 4
HAPAPPHC_04212	5.79e-222	-	-	-	PT	-	-	-	Domain of unknown function (DUF4974)
HAPAPPHC_04213	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HAPAPPHC_04214	1.05e-36	-	-	-	F	ko:K21572	-	ko00000,ko02000	Pfam:SusD
HAPAPPHC_04215	1.18e-145	-	-	-	F	ko:K21572	-	ko00000,ko02000	Pfam:SusD
HAPAPPHC_04216	1.31e-269	-	-	-	C	-	-	-	FAD dependent oxidoreductase
HAPAPPHC_04217	4.5e-76	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
HAPAPPHC_04218	1.44e-56	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HAPAPPHC_04219	4.72e-92	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
HAPAPPHC_04220	1.34e-258	amiA	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	N-acetylmuramoyl-L-alanine amidase
HAPAPPHC_04221	7.5e-186	-	-	-	Q	ko:K02067	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Virulence factor Mce family protein
HAPAPPHC_04222	1.01e-156	-	-	-	T	-	-	-	Transcriptional regulator
HAPAPPHC_04223	4.93e-304	qseC	-	-	T	-	-	-	Histidine kinase
HAPAPPHC_04224	5.15e-100	-	-	-	S	-	-	-	Putative beta-lactamase-inhibitor-like, PepSY-like
HAPAPPHC_04225	1.93e-206	-	-	-	S	-	-	-	Putative beta-lactamase-inhibitor-like, PepSY-like
HAPAPPHC_04226	3.71e-146	-	-	-	S	-	-	-	Protein of unknown function (DUF3256)
HAPAPPHC_04227	5.61e-194	-	-	-	EG	ko:K08978	-	ko00000,ko02000	EamA-like transporter family
HAPAPPHC_04228	4.01e-185	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HAPAPPHC_04229	0.0	-	-	-	P	ko:K07085	-	ko00000	Predicted Permease Membrane Region
HAPAPPHC_04230	0.0	-	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	PFAM alpha-L-arabinofuranosidase domain protein
HAPAPPHC_04231	3.23e-90	-	-	-	S	-	-	-	YjbR
HAPAPPHC_04232	0.0	uvrD2	-	-	L	-	-	-	COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member
HAPAPPHC_04233	2.91e-310	-	-	-	EGP	ko:K08169	-	ko00000,ko02000	Sugar (and other) transporter
HAPAPPHC_04234	4.67e-139	-	-	-	S	-	-	-	Domain of unknown function (DUF4923)
HAPAPPHC_04235	0.0	-	-	-	E	-	-	-	Oligoendopeptidase f
HAPAPPHC_04236	2e-241	fba	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate
HAPAPPHC_04237	4.78e-55	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	50S ribosomal protein L31 type B
HAPAPPHC_04238	3.9e-267	mdsC	-	-	S	-	-	-	Phosphotransferase enzyme family
HAPAPPHC_04239	8.31e-91	-	-	-	E	-	-	-	Stress responsive alpha-beta barrel domain protein
HAPAPPHC_04240	1.94e-306	-	-	-	T	-	-	-	PAS domain
HAPAPPHC_04241	6.64e-167	-	-	-	T	ko:K02481	-	ko00000,ko02022	Sigma-54 interaction domain
HAPAPPHC_04242	2.28e-127	-	-	-	T	ko:K02481	-	ko00000,ko02022	Sigma-54 interaction domain
HAPAPPHC_04243	0.0	-	-	-	MU	-	-	-	Outer membrane efflux protein
HAPAPPHC_04244	1.23e-161	-	-	-	T	-	-	-	LytTr DNA-binding domain
HAPAPPHC_04245	4.4e-233	-	-	-	T	-	-	-	Histidine kinase
HAPAPPHC_04246	7.22e-76	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Prokaryotic diacylglycerol kinase
HAPAPPHC_04247	8.99e-133	-	-	-	I	-	-	-	Acid phosphatase homologues
HAPAPPHC_04248	3.83e-296	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score
HAPAPPHC_04249	4.9e-44	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HAPAPPHC_04250	3.87e-225	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HAPAPPHC_04251	5.77e-306	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HAPAPPHC_04252	2.82e-297	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HAPAPPHC_04253	2.94e-305	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score
HAPAPPHC_04254	1.19e-314	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system permease component
HAPAPPHC_04255	2.14e-296	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HAPAPPHC_04256	7.84e-113	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system permease component
HAPAPPHC_04257	8.39e-172	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system permease component
HAPAPPHC_04259	2.59e-152	ytrE_3	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HAPAPPHC_04260	1.05e-314	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HAPAPPHC_04261	6.91e-298	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
HAPAPPHC_04262	2.15e-75	-	-	-	DJ	-	-	-	Psort location Cytoplasmic, score 8.96
HAPAPPHC_04264	7.33e-150	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HAPAPPHC_04265	2.53e-130	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HAPAPPHC_04266	5.89e-296	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HAPAPPHC_04267	8.28e-257	-	-	-	M	ko:K02005	-	ko00000	HlyD family secretion protein
HAPAPPHC_04268	2.12e-166	-	-	-	-	-	-	-	-
HAPAPPHC_04269	5.94e-152	-	-	-	-	-	-	-	-
HAPAPPHC_04271	2.33e-201	-	-	-	S	-	-	-	COG NOG14441 non supervised orthologous group
HAPAPPHC_04272	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
HAPAPPHC_04273	4.68e-289	dcuB	-	-	S	ko:K07791,ko:K07792	ko02020,map02020	ko00000,ko00001,ko02000	Anaerobic c4-dicarboxylate membrane transporter
HAPAPPHC_04274	3.25e-85	-	-	-	O	-	-	-	F plasmid transfer operon protein
HAPAPPHC_04275	3.87e-282	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
HAPAPPHC_04276	6.37e-60	marR	-	-	K	-	-	-	Winged helix DNA-binding domain
HAPAPPHC_04277	2.15e-145	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HAPAPPHC_04278	0.0	-	-	-	H	-	-	-	Outer membrane protein beta-barrel family
HAPAPPHC_04279	1.21e-82	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2141)
HAPAPPHC_04280	2.37e-126	-	-	-	S	-	-	-	Appr-1'-p processing enzyme
HAPAPPHC_04281	9.83e-151	-	-	-	-	-	-	-	-
HAPAPPHC_04282	4.74e-281	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HAPAPPHC_04283	0.0	-	-	-	L	-	-	-	Reverse transcriptase (RNA-dependent DNA polymerase)
HAPAPPHC_04284	7.66e-71	-	-	-	S	-	-	-	COG3943, virulence protein
HAPAPPHC_04285	6.36e-41	-	-	-	S	-	-	-	Protein of unknown function (DUF2971)
HAPAPPHC_04286	1.14e-65	-	-	-	S	-	-	-	DNA binding domain, excisionase family
HAPAPPHC_04287	4.95e-63	-	-	-	-	-	-	-	-
HAPAPPHC_04288	4.28e-72	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HAPAPPHC_04289	6.66e-79	-	-	-	S	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
HAPAPPHC_04290	0.0	-	-	-	S	-	-	-	COG NOG09947 non supervised orthologous group
HAPAPPHC_04291	0.0	-	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	DNA topoisomerase
HAPAPPHC_04292	8.12e-94	-	-	-	S	-	-	-	COG NOG19108 non supervised orthologous group
HAPAPPHC_04293	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
HAPAPPHC_04295	0.0	-	-	-	L	-	-	-	Reverse transcriptase (RNA-dependent DNA polymerase)
HAPAPPHC_04296	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
HAPAPPHC_04297	0.0	tetP	-	-	J	ko:K18220	-	br01600,ko00000,ko01504	Elongation Factor G, domain II
HAPAPPHC_04298	6.14e-259	-	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HAPAPPHC_04299	0.0	-	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HAPAPPHC_04300	2.46e-305	-	-	-	MU	-	-	-	Efflux transporter, outer membrane factor lipoprotein, NodT family
HAPAPPHC_04301	8.61e-39	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HAPAPPHC_04302	1.2e-234	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Efflux ABC transporter, permease protein
HAPAPPHC_04303	7.43e-45	-	-	-	M	ko:K02005	-	ko00000	Barrel-sandwich domain of CusB or HlyD membrane-fusion
HAPAPPHC_04304	1.83e-101	-	-	-	H	-	-	-	dihydrofolate reductase family protein K00287
HAPAPPHC_04305	5.86e-136	rteC	-	-	S	-	-	-	RteC protein
HAPAPPHC_04306	0.0	-	-	-	U	-	-	-	COG COG3505 Type IV secretory pathway, VirD4 components
HAPAPPHC_04307	3.74e-284	-	-	-	U	-	-	-	Relaxase mobilization nuclease domain protein
HAPAPPHC_04308	4.28e-92	-	-	-	-	-	-	-	-
HAPAPPHC_04309	5.05e-112	-	-	-	D	-	-	-	COG NOG26689 non supervised orthologous group
HAPAPPHC_04310	1.59e-46	-	-	-	D	-	-	-	COG NOG26689 non supervised orthologous group
HAPAPPHC_04311	6.53e-94	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HAPAPPHC_04312	9.11e-11	-	-	-	L	-	-	-	PFAM Transposase IS116 IS110 IS902 family
HAPAPPHC_04313	5.9e-78	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HAPAPPHC_04314	4.4e-47	-	-	-	S	-	-	-	Protein of unknown function (DUF3408)
HAPAPPHC_04315	9.3e-148	-	-	-	S	-	-	-	Conjugal transfer protein traD
HAPAPPHC_04316	4.45e-39	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HAPAPPHC_04317	0.0	-	2.7.7.49	-	H	ko:K00986	-	ko00000,ko01000	Group II intron, maturase-specific domain
HAPAPPHC_04318	1.97e-13	-	-	-	S	-	-	-	Conjugative transposon protein TraE
HAPAPPHC_04319	5.21e-71	-	-	-	S	-	-	-	COG NOG30259 non supervised orthologous group
HAPAPPHC_04320	7.54e-99	-	-	-	U	-	-	-	Conjugation system ATPase, TraG family
HAPAPPHC_04321	0.0	-	-	-	U	-	-	-	Conjugation system ATPase, TraG family
HAPAPPHC_04322	3.56e-86	-	-	-	S	-	-	-	COG NOG30362 non supervised orthologous group
HAPAPPHC_04323	2.65e-114	-	-	-	U	-	-	-	Domain of unknown function (DUF4141)
HAPAPPHC_04324	1.01e-226	traJ	-	-	S	-	-	-	Conjugative transposon TraJ protein
HAPAPPHC_04325	4.35e-144	traK	-	-	U	-	-	-	Conjugative transposon TraK protein
HAPAPPHC_04326	4.46e-66	-	-	-	S	-	-	-	Protein of unknown function (DUF3989)
HAPAPPHC_04327	5.41e-310	traM	-	-	S	-	-	-	Conjugative transposon TraM protein
HAPAPPHC_04328	4.11e-251	-	-	-	U	-	-	-	Conjugative transposon TraN protein
HAPAPPHC_04329	2.28e-138	-	-	-	S	-	-	-	COG NOG19079 non supervised orthologous group
HAPAPPHC_04330	5.67e-196	-	-	-	L	-	-	-	CHC2 zinc finger domain protein
HAPAPPHC_04331	1.79e-117	-	-	-	S	-	-	-	Domain of unknown function, B. Theta Gene description (DUF3872)
HAPAPPHC_04332	1.52e-116	-	3.2.1.17	-	S	ko:K01185	-	ko00000,ko01000	lysozyme
HAPAPPHC_04333	5.93e-124	-	3.2.1.17	-	S	ko:K01185	-	ko00000,ko01000	lysozyme
HAPAPPHC_04334	5.33e-119	-	-	-	S	-	-	-	Domain of unknown function, B. Theta Gene description (DUF3872)
HAPAPPHC_04335	8.92e-217	-	-	-	L	-	-	-	CHC2 zinc finger
HAPAPPHC_04336	1.95e-139	-	-	-	S	-	-	-	Conjugal transfer protein TraO
HAPAPPHC_04337	3.31e-238	-	-	-	U	-	-	-	Domain of unknown function (DUF4138)
HAPAPPHC_04338	5.67e-313	traM	-	-	S	-	-	-	Conjugative transposon TraM protein
HAPAPPHC_04339	2.79e-69	-	-	-	S	-	-	-	Protein of unknown function (DUF3989)
HAPAPPHC_04340	4.35e-144	traK	-	-	U	-	-	-	Conjugative transposon TraK protein
HAPAPPHC_04341	5.81e-226	traJ	-	-	S	-	-	-	Conjugative transposon TraJ protein
HAPAPPHC_04342	3.94e-116	-	-	-	U	-	-	-	Domain of unknown function (DUF4141)
HAPAPPHC_04343	6.14e-87	-	-	-	S	-	-	-	COG NOG30362 non supervised orthologous group
HAPAPPHC_04344	0.0	-	-	-	U	-	-	-	conjugation system ATPase
HAPAPPHC_04345	8.08e-103	-	-	-	U	-	-	-	conjugation system ATPase
HAPAPPHC_04346	6.33e-72	-	-	-	S	-	-	-	COG NOG30259 non supervised orthologous group
HAPAPPHC_04347	0.000348	traG	-	-	U	-	-	-	Conjugation system ATPase, TraG family
HAPAPPHC_04348	0.0	-	2.7.7.49	-	H	ko:K00986	-	ko00000,ko01000	Group II intron, maturase-specific domain
HAPAPPHC_04349	2.21e-39	-	-	-	S	-	-	-	Domain of unknown function (DUF4134)
HAPAPPHC_04350	7.91e-164	-	-	-	S	-	-	-	Conjugal transfer protein traD
HAPAPPHC_04351	1.81e-78	-	-	-	S	-	-	-	Protein of unknown function (DUF3408)
HAPAPPHC_04352	6.99e-99	-	-	-	S	-	-	-	Protein of unknown function (DUF3408)
HAPAPPHC_04353	5.22e-176	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ/CobB/MinD/ParA nucleotide binding domain
HAPAPPHC_04354	1.81e-54	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HAPAPPHC_04355	1.97e-92	-	-	-	S	-	-	-	COG NOG29380 non supervised orthologous group
HAPAPPHC_04356	3.05e-299	-	-	-	U	-	-	-	Relaxase mobilization nuclease domain protein
HAPAPPHC_04357	0.0	-	-	-	U	-	-	-	Type IV secretory system Conjugative DNA transfer
HAPAPPHC_04358	0.0	-	-	-	L	-	-	-	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HAPAPPHC_04359	0.0	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
HAPAPPHC_04360	1.52e-143	rteC	-	-	S	-	-	-	RteC protein
HAPAPPHC_04361	9.48e-97	-	-	-	H	-	-	-	RibD C-terminal domain
HAPAPPHC_04362	0.0	zraR	-	-	T	ko:K07713	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Bacterial regulatory protein, Fis family
HAPAPPHC_04363	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HAPAPPHC_04364	0.0	tetP	-	-	J	ko:K18220	-	br01600,ko00000,ko01504	Elongation Factor G, domain II
HAPAPPHC_04365	1.72e-207	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HAPAPPHC_04366	3.44e-92	-	-	-	S	-	-	-	SnoaL-like polyketide cyclase
HAPAPPHC_04367	9.71e-70	-	-	-	S	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
HAPAPPHC_04368	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
HAPAPPHC_04369	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
HAPAPPHC_04370	4.73e-102	-	-	-	S	-	-	-	Domain of unknown function (DUF1896)
HAPAPPHC_04371	0.0	-	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	DNA topoisomerase
HAPAPPHC_04372	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF4099)
HAPAPPHC_04373	9.47e-79	-	-	-	S	-	-	-	Helix-turn-helix domain
HAPAPPHC_04374	1.69e-73	-	-	-	L	-	-	-	Helix-turn-helix domain
HAPAPPHC_04375	7.04e-63	-	-	-	-	-	-	-	-
HAPAPPHC_04376	8.37e-66	-	-	-	L	-	-	-	Helix-turn-helix domain
HAPAPPHC_04377	9.68e-83	-	-	-	S	-	-	-	COG3943, virulence protein
HAPAPPHC_04378	9.53e-305	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HAPAPPHC_04379	1.44e-229	-	-	-	L	-	-	-	Endonuclease/Exonuclease/phosphatase family
HAPAPPHC_04380	0.0	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HAPAPPHC_04381	3.48e-190	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
HAPAPPHC_04382	0.0	lon	3.4.21.53	-	O	ko:K01338	ko04112,map04112	ko00000,ko00001,ko01000,ko01002	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HAPAPPHC_04383	7.51e-109	lon	3.4.21.53	-	O	ko:K01338	ko04112,map04112	ko00000,ko00001,ko01000,ko01002	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HAPAPPHC_04384	8.94e-150	smtA	2.1.1.223	-	J	ko:K15460	-	ko00000,ko01000,ko03016	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
HAPAPPHC_04385	8.4e-234	-	-	-	I	-	-	-	Lipid kinase
HAPAPPHC_04386	1.31e-287	bioF	2.3.1.29, 2.3.1.47	-	E	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	2-amino-3-ketobutyrate CoA ligase
HAPAPPHC_04387	2.23e-267	yaaT	-	-	S	-	-	-	PSP1 C-terminal domain protein
HAPAPPHC_04388	0.0	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
HAPAPPHC_04389	0.0	mrdA	3.4.16.4	-	M	ko:K05515	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HAPAPPHC_04390	6.4e-113	mreD	-	-	S	-	-	-	rod shape-determining protein MreD
HAPAPPHC_04391	6.39e-198	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	shape-determining protein MreC
HAPAPPHC_04392	1.35e-238	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein MreB
HAPAPPHC_04393	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
HAPAPPHC_04394	2.85e-60	-	-	-	I	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HAPAPPHC_04395	6.95e-18	-	-	-	I	-	-	-	Acyltransferase family
HAPAPPHC_04396	4.29e-50	-	-	-	S	-	-	-	Protein of unknown function DUF86
HAPAPPHC_04397	7.29e-61	-	-	-	S	ko:K07075	-	ko00000	Nucleotidyltransferase domain
HAPAPPHC_04398	1.39e-195	-	-	-	K	-	-	-	BRO family, N-terminal domain
HAPAPPHC_04399	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
HAPAPPHC_04400	0.0	ltaS2	-	-	M	-	-	-	Sulfatase
HAPAPPHC_04401	0.0	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
HAPAPPHC_04402	7.65e-62	zapA	-	-	D	ko:K09888	-	ko00000,ko03036	Cell division protein ZapA
HAPAPPHC_04403	1.32e-58	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HAPAPPHC_04404	7.03e-40	-	-	-	S	-	-	-	Winged helix-turn-helix domain (DUF2582)
HAPAPPHC_04405	3.98e-160	-	-	-	S	-	-	-	B3/4 domain
HAPAPPHC_04406	1.01e-111	-	-	-	S	ko:K05810	-	ko00000,ko01000	Belongs to the multicopper oxidase YfiH RL5 family
HAPAPPHC_04407	3.93e-57	-	-	-	S	ko:K05810	-	ko00000,ko01000	Belongs to the multicopper oxidase YfiH RL5 family
HAPAPPHC_04408	1.25e-264	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HAPAPPHC_04409	1.8e-130	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HAPAPPHC_04410	1.46e-139	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Hypoxanthine phosphoribosyltransferase
HAPAPPHC_04411	0.0	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HAPAPPHC_04412	0.0	-	-	-	G	-	-	-	Domain of Unknown Function (DUF1080)
HAPAPPHC_04413	0.0	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HAPAPPHC_04414	6.26e-214	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
HAPAPPHC_04415	8.25e-66	-	-	-	K	ko:K03088	-	ko00000,ko03021	DNA-templated transcription, initiation
HAPAPPHC_04416	1.77e-202	-	-	-	PT	-	-	-	Sigma factor regulatory protein, FecR PupR family
HAPAPPHC_04417	2.87e-52	-	-	-	K	ko:K03088	-	ko00000,ko03021	DNA-templated transcription, initiation
HAPAPPHC_04418	0.0	-	-	-	P	-	-	-	TonB dependent receptor
HAPAPPHC_04419	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	SusD family
HAPAPPHC_04420	3.92e-164	-	-	-	S	-	-	-	Endonuclease/Exonuclease/phosphatase family
HAPAPPHC_04421	9.61e-247	-	-	-	S	-	-	-	Domain of unknown function (DUF4831)
HAPAPPHC_04422	0.0	-	-	-	E	ko:K03305	-	ko00000	amino acid peptide transporter
HAPAPPHC_04423	4.43e-94	-	-	-	-	-	-	-	-
HAPAPPHC_04424	4e-234	bioB	2.8.1.6	-	H	ko:K01012	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HAPAPPHC_04425	7.71e-314	bioA	2.6.1.62	-	H	ko:K00833	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
HAPAPPHC_04426	2.54e-286	bioF	2.3.1.29, 2.3.1.47	-	E	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	8-amino-7-oxononanoate synthase
HAPAPPHC_04427	1.35e-163	-	3.1.1.85	-	S	ko:K09789	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Protein of unknown function (DUF452)
HAPAPPHC_04428	3.05e-185	bioC	2.1.1.197	-	H	ko:K02169	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway
HAPAPPHC_04429	5.46e-161	bioD	6.3.3.3	-	H	ko:K01935	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HAPAPPHC_04430	6.58e-88	-	-	-	S	-	-	-	Protein of unknown function (DUF1232)
HAPAPPHC_04431	0.0	-	-	-	P	-	-	-	Psort location OuterMembrane, score
HAPAPPHC_04432	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	Pfam:SusD
HAPAPPHC_04433	4.07e-133	ykgB	-	-	S	-	-	-	membrane
HAPAPPHC_04434	2.06e-185	-	-	-	K	-	-	-	Helix-turn-helix domain
HAPAPPHC_04435	3.64e-93	trxA2	-	-	O	-	-	-	Thioredoxin
HAPAPPHC_04436	8.91e-218	-	-	-	-	-	-	-	-
HAPAPPHC_04437	1.7e-32	-	-	-	-	-	-	-	-
HAPAPPHC_04438	8.24e-46	-	-	-	-	-	-	-	-
HAPAPPHC_04439	3.51e-119	-	-	-	C	-	-	-	lyase activity
HAPAPPHC_04440	3.36e-118	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70, region 4